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Search of human proteins with 22748877
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22748877 basic helix-loop-helix domain containing, class B,
5 [Homo sapiens]
(381 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 754 0.0
gi|57529222 basic helix-loop-helix domain containing, class B, 4... 177 1e-44
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 138 9e-33
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] 113 2e-25
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] 88 1e-17
gi|4507741 twist [Homo sapiens] 87 2e-17
gi|109255251 loricrin [Homo sapiens] 80 4e-15
gi|195972866 keratin 10 [Homo sapiens] 74 3e-13
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 72 8e-13
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 72 8e-13
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 71 1e-12
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 71 1e-12
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 71 1e-12
gi|55956899 keratin 9 [Homo sapiens] 70 3e-12
gi|24432032 zinc finger protein 503 [Homo sapiens] 69 9e-12
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 68 1e-11
gi|119395750 keratin 1 [Homo sapiens] 67 3e-11
gi|116805332 musculin [Homo sapiens] 67 3e-11
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 64 2e-10
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 64 3e-10
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 64 3e-10
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 64 3e-10
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 64 3e-10
gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens] 64 3e-10
gi|47132620 keratin 2 [Homo sapiens] 63 4e-10
gi|31077092 neurogenin 2 [Homo sapiens] 63 5e-10
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 62 7e-10
gi|4885075 atonal homolog 1 [Homo sapiens] 62 9e-10
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 61 2e-09
gi|153792190 neurogenic differentiation 4 [Homo sapiens] 60 2e-09
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 754 bits (1946), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 1 MERGMHLGAAAAGEDDLFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPASSSSS 60
MERGMHLGAAAAGEDDLFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPASSSSS
Sbjct: 1 MERGMHLGAAAAGEDDLFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPASSSSS 60
Query: 61 PLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLP 120
PLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLP
Sbjct: 61 PLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLP 120
Query: 121 AGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKA 180
AGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKA
Sbjct: 121 AGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKA 180
Query: 181 AEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ 240
AEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ
Sbjct: 181 AEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ 240
Query: 241 KALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 300
KALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL
Sbjct: 241 KALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 300
Query: 301 EEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCP 360
EEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCP
Sbjct: 301 EEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCP 360
Query: 361 EKCALFNSVSSSLCKQCTEKP 381
EKCALFNSVSSSLCKQCTEKP
Sbjct: 361 EKCALFNSVSSSLCKQCTEKP 381
>gi|57529222 basic helix-loop-helix domain containing, class B, 4
[Homo sapiens]
Length = 225
Score = 177 bits (450), Expect = 1e-44
Identities = 115/226 (50%), Positives = 133/226 (58%), Gaps = 38/226 (16%)
Query: 176 GGAKAAEGCSNAHLHGGASVPPGGLGGG--GGGGSSSGSSG------GGGGSGSGSGGSS 227
G A AA G + +G A P G G G GG + SG SG
Sbjct: 18 GYAAAAAGLA----YGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDED 73
Query: 228 S------------SSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSP 275
S++ ++ +EQ++LRL+INARERRRMHDLNDALD LRAVIPYAHSP
Sbjct: 74 DAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSP 133
Query: 276 SVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALH 335
SVRKLSKIATLLLAKNYILMQAQAL+EMRRLVA+LNQGQ + AA AA L
Sbjct: 134 SVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGL---------AAPVNAAPLT 184
Query: 336 PALGAYEQAAGYPFSAGLPPAASCPEKCALFNSVSSSLCKQCTEKP 381
P + QA PFSAG CP+KCA F+ S+LCK C EKP
Sbjct: 185 P----FGQATVCPFSAG-AALGPCPDKCAAFSGTPSALCKHCHEKP 225
>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
sapiens]
Length = 323
Score = 138 bits (347), Expect = 9e-33
Identities = 91/191 (47%), Positives = 113/191 (59%), Gaps = 22/191 (11%)
Query: 198 GGLGGGGGG-GSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ------KALRLNINAR 250
G +G G G G SG S S S +SS+++SS+KK K+Q + LRL IN+R
Sbjct: 57 GAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSR 116
Query: 251 ERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYL 310
ER+RMHDLN A+D LR V+PYAH PSVRKLSKIATLLLA+NYILM +LEEM+RLV+ +
Sbjct: 117 ERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEI 176
Query: 311 NQGQAIS---------AASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCPE 361
G A S P AA A AAA H A+ A +P LPPAA+
Sbjct: 177 YGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAH---AAHHPAVHHPI---LPPAAAAAA 230
Query: 362 KCALFNSVSSS 372
A +VSS+
Sbjct: 231 AAAAAAAVSSA 241
Score = 33.1 bits (74), Expect = 0.43
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 173 AGGGGAKAAEGCSNAHLHG------GASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSG 224
A A AA S+A L G G+ PP GL +++ GGGGGSG+ G
Sbjct: 227 AAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGG 284
Score = 32.0 bits (71), Expect = 0.95
Identities = 41/144 (28%), Positives = 54/144 (37%), Gaps = 31/144 (21%)
Query: 4 GMHLGAAAAGEDDLFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPA-------- 55
G H G + L L A+T+ AA + P + + PP A
Sbjct: 179 GHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAV 238
Query: 56 SSSSSP------LGCFEPADPEG-----AGLLLPPPGGGGGGSAGSGG-GGGGGVGVPGL 103
SS+S P +G P P G + P GGGGGGS SGG GG+ P
Sbjct: 239 SSASLPGSGLPSVGSIRP--PHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCS 296
Query: 104 L---------VGSAGVGGDPSLSS 118
+ V + G G P L+S
Sbjct: 297 MCQVPPPHHHVSAMGAGSLPRLTS 320
>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
Length = 272
Score = 113 bits (283), Expect = 2e-25
Identities = 74/153 (48%), Positives = 90/153 (58%), Gaps = 14/153 (9%)
Query: 218 GSGSGSGGSSSSSSSSSKKSKEQ------KALRLNINARERRRMHDLNDALDELRAVIPY 271
G G+ ++ SS K K+Q + LRL IN RER+RMHDLN A+D LR V+PY
Sbjct: 53 GESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPY 112
Query: 272 AHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQG--QAISAASLPSSAAAAA 329
AH PSVRKLSKIATLLLA+NYILM +LEEM+RLV + G A ++ SA A
Sbjct: 113 AHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPA 172
Query: 330 AAA----ALHPALGAYEQA--AGYPFSAGLPPA 356
AA +HP LG + A P SA PA
Sbjct: 173 HAANSVHPVHPILGGALSSGNASSPLSAASLPA 205
>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
Length = 271
Score = 88.2 bits (217), Expect = 1e-17
Identities = 61/132 (46%), Positives = 77/132 (58%), Gaps = 13/132 (9%)
Query: 218 GSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVI-PY--AHS 274
G G GSG S+ K ++Q+ LR IN+RER+RM DLN A+D LR VI PY AH
Sbjct: 81 GPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHC 140
Query: 275 PSV--RKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISA-----ASLPSSAAA 327
RKLSKIATLLLA+NYIL+ +L+E+RR L +G +A A LP AAA
Sbjct: 141 QGAPGRKLSKIATLLLARNYILLLGSSLQELRRA---LGEGAGPAAPRLLLAGLPLLAAA 197
Query: 328 AAAAAALHPALG 339
+ A+G
Sbjct: 198 PGSVLLAPGAVG 209
>gi|4507741 twist [Homo sapiens]
Length = 202
Score = 87.0 bits (214), Expect = 2e-17
Identities = 65/170 (38%), Positives = 78/170 (45%), Gaps = 21/170 (12%)
Query: 142 SGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLG 201
S SP DDS E D + P GG K +A GG + P G G
Sbjct: 6 SSSPVSPADDSLSNSE-----EEPDRQQPPSGKRGGRKRRSSRRSA---GGGAGPGGAAG 57
Query: 202 GGGGGGSSSGS----------SGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARE 251
GG GGG GS +G GGG G+G GG SSS S + +E + R+ N RE
Sbjct: 58 GGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRE 117
Query: 252 RRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALE 301
R+R LN+A LR +IP S KLSKI TL LA YI Q L+
Sbjct: 118 RQRTQSLNEAFAALRKIIPTLPSD---KLSKIQTLKLAARYIDFLYQVLQ 164
Score = 32.3 bits (72), Expect = 0.73
Identities = 16/36 (44%), Positives = 16/36 (44%)
Query: 66 EPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVP 101
EP P G GGGG AG GGG G G P
Sbjct: 65 EPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSP 100
Score = 30.0 bits (66), Expect = 3.6
Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 25/84 (29%)
Query: 49 PPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGG------------------SAGS 90
P R++P S G + AG P G GGG SAG
Sbjct: 24 PDRQQPPSGKRG--GRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGC 81
Query: 91 GGGGGGGVGVPGLLVGSAGVGGDP 114
GGGGG G G GS+ GG P
Sbjct: 82 GGGGGAGGG-----GGSSSGGGSP 100
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 79.7 bits (195), Expect = 4e-15
Identities = 64/174 (36%), Positives = 76/174 (43%), Gaps = 18/174 (10%)
Query: 81 GGGGGGSAGSGGG--GGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKY---GESASR 135
GG GGGS+GSG G GGGG G GS+G GG + G+ +KY G S+
Sbjct: 40 GGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGG 99
Query: 136 GSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEG-------CSNAH 188
GS SSGG S S G +G +GGG + G
Sbjct: 100 GSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQ 159
Query: 189 LHGGASVPPGGLGG------GGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKK 236
+GG S GG GGGGGS G SGGG G G GS G S S SS++
Sbjct: 160 SYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQ 213
Score = 75.9 bits (185), Expect = 6e-14
Identities = 65/205 (31%), Positives = 81/205 (39%), Gaps = 24/205 (11%)
Query: 56 SSSSSPLGCFEP----ADPEGAGLLLPPPGGGGGGSAG---SGGGGGGGVGVP-----GL 103
SS GCF + G+G GG GG +G SGGGG G V G+
Sbjct: 105 SSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGV 164
Query: 104 LVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAG 163
G + GG SS G ++C G + G SSGG S S ++ +
Sbjct: 165 SSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGG--GSSGGSGSGYVSSQ---QVTQTSC 219
Query: 164 VADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGG-------GGGGGSSSGSSGGG 216
P G+ GGG GC ++ GG+S GG G GGG G S GG
Sbjct: 220 APQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGG 279
Query: 217 GGSGSGSGGSSSSSSSSSKKSKEQK 241
GG GS GGS S +QK
Sbjct: 280 GGGGSSVGGSGSGKGVPICHQTQQK 304
Score = 75.1 bits (183), Expect = 1e-13
Identities = 66/193 (34%), Positives = 76/193 (39%), Gaps = 34/193 (17%)
Query: 82 GGGGGSAGSGGG----------------------GGGGVGVPGLLVGSAGVGGDPSLSSL 119
GGGGG GSGGG GGGG G GS+G GG +
Sbjct: 21 GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC 80
Query: 120 PAGAALCLKY---GESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGG 176
G+ +KY G S+ GS SSGG S S G +G +GGG
Sbjct: 81 GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGG 140
Query: 177 GAKAAEGCSNAHLHGGASVPPGGL--GGGGGGGSSSGSSGGGGGS-------GSGSGGSS 227
+ G GG+ GG GGGS SSGGGGGS GSG GG S
Sbjct: 141 SGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGS 200
Query: 228 SSSSSSSKKSKEQ 240
S S S S +Q
Sbjct: 201 SGGSGSGYVSSQQ 213
Score = 69.3 bits (168), Expect = 5e-12
Identities = 56/158 (35%), Positives = 61/158 (38%), Gaps = 32/158 (20%)
Query: 81 GGGGGGSAGSG----GGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRG 136
GGGGGGS G G GGGG G G G G +G GG G G
Sbjct: 23 GGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYS---------------GGGCGGG 67
Query: 137 SVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVP 196
S GG G C G + GGG + GC ++ G
Sbjct: 68 SSGGGGGG-------GIGGC-----GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFS 115
Query: 197 PGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSS 234
GG GG GGGS SSGGGG SG GSG SS S
Sbjct: 116 SGG-GGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFS 152
Score = 53.1 bits (126), Expect = 4e-07
Identities = 31/70 (44%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 168 RASPGAGGGGAKAAEGCS---NAHLHGGASVPPGGLGGGGG---GGSSSGSSGGGGGSGS 221
+ S G GGGG GC GG+S G GGGG GG GSSGGGGG G
Sbjct: 18 KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGI 77
Query: 222 GSGGSSSSSS 231
G G S S
Sbjct: 78 GGCGGGSGGS 87
Score = 37.4 bits (85), Expect = 0.023
Identities = 20/38 (52%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 195 VPPGGLGGGGGGGSSSGSS-GGGGGSGSGSGGSSSSSS 231
V G GGGGGG G GGGGSG GS GS S
Sbjct: 17 VKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYS 54
Score = 33.1 bits (74), Expect = 0.43
Identities = 32/93 (34%), Positives = 35/93 (37%), Gaps = 31/93 (33%)
Query: 45 SLAPPPRERPASSS---SSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGG-------- 93
S AP P SS S GCF GGGGGS+G GGG
Sbjct: 218 SCAPQPSYGGGSSGGGGSGGSGCFS--------------SGGGGGSSGCGGGSSGIGSGC 263
Query: 94 ---GGGGV---GVPGLLVGSAGVGGDPSLSSLP 120
GGG V G G G + VGG S +P
Sbjct: 264 IISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVP 296
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 73.6 bits (179), Expect = 3e-13
Identities = 60/162 (37%), Positives = 68/162 (41%), Gaps = 43/162 (26%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
GGGG G GGG GGG G G G G +G S+ G
Sbjct: 460 GGGGRGGGSFGGGYGGGSSGGGSSGGGHGGG-----------------HGGSSGGGYGGG 502
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGL 200
SSGG S G GGG + G S++ +GG S GG
Sbjct: 503 SSGGGSS----------------------GGGYGGGSSSGGHGGSSSGGYGGGS--SGGG 538
Query: 201 GGGGGGGSSSG--SSGGGGGSGSGSGGSSSSSSSSSKKSKEQ 240
GGG GGGSS G SSGGG G GS SGG SSSS S +S +
Sbjct: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580
Score = 60.5 bits (145), Expect = 2e-09
Identities = 59/187 (31%), Positives = 71/187 (37%), Gaps = 33/187 (17%)
Query: 82 GGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAES 141
GGGGG GGG GGG GV L + S S SL G + G S SRGS
Sbjct: 17 GGGGG----GGGCGGGGGVSSLRISS-------SKGSLGGGFSSGGFSGGSFSRGSSGGG 65
Query: 142 SGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSN-----AHLHGGASVP 196
G S G G GGG + + G S+ GG S
Sbjct: 66 CFGGSSGGYGGLG-----------------GFGGGSFRGSYGSSSFGGSYGGSFGGGSFG 108
Query: 197 PGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMH 256
G GGG GG G G GGG G G GG S + K + + RL + R +
Sbjct: 109 GGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALE 168
Query: 257 DLNDALD 263
+ N L+
Sbjct: 169 ESNYELE 175
Score = 60.5 bits (145), Expect = 2e-09
Identities = 63/189 (33%), Positives = 73/189 (38%), Gaps = 39/189 (20%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
GGGGGG GG GGG GV L + S S SL G + G S SRGS
Sbjct: 17 GGGGGG-----GGCGGGGGVSSLRISS-------SKGSLGGGFSSGGFSGGSFSRGSSGG 64
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGL 200
G S G G GGG + + G S+ G S G
Sbjct: 65 GCFGGSSGGYGGLG-----------------GFGGGSFRGSYGSSSFGGSYGGSFGGGSF 107
Query: 201 GGGG-GGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMHDLN 259
GGG GGGS G GGGG G G GG S +K N+N R L
Sbjct: 108 GGGSFGGGSFGGGGFGGGGFGGGFGG--GFGGDGGLLSGNEKVTMQNLNDR-------LA 158
Query: 260 DALDELRAV 268
LD++RA+
Sbjct: 159 SYLDKVRAL 167
Score = 57.0 bits (136), Expect = 3e-08
Identities = 48/144 (33%), Positives = 53/144 (36%), Gaps = 33/144 (22%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
GG GGGS+G G GGG G G GS+G G YG +S G
Sbjct: 471 GGYGGGSSGGGSSGGGHGGGHG---GSSGGG-----------------YGGGSSGGG--- 507
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGL 200
SSGG S G +S G GGG + G GG S GG
Sbjct: 508 SSGGGYGGGSSSGGH----------GGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGY 557
Query: 201 GGGGGGGSSSGSSGGGGGSGSGSG 224
GGG G SS G G S G
Sbjct: 558 GGGSSSGGHKSSSSGSVGESSSKG 581
Score = 49.3 bits (116), Expect = 6e-06
Identities = 32/73 (43%), Positives = 35/73 (47%), Gaps = 15/73 (20%)
Query: 172 GAGGGGAKAAEGCSNAHLHGGASVPPGGLGGG-------------GGGGSSSGSSGGGGG 218
G+ GGG + G S +GG S G GGG GGG S GSSGGG G
Sbjct: 457 GSSGGGGRG--GGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG 514
Query: 219 SGSGSGGSSSSSS 231
GS SGG SSS
Sbjct: 515 GGSSSGGHGGSSS 527
Score = 48.9 bits (115), Expect = 8e-06
Identities = 29/66 (43%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 169 ASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSS 228
+S G G GG G GG+S G G GGG G SSG GGG SG GS G
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSS----GGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513
Query: 229 SSSSSS 234
SSS
Sbjct: 514 GGGSSS 519
Score = 48.5 bits (114), Expect = 1e-05
Identities = 28/54 (51%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 182 EGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGG--GGGSGSGSGGSSSSSSSS 233
EG S GG S G GG GGGSS G GG GG SG G GG SS SS
Sbjct: 456 EGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSS 509
Score = 46.6 bits (109), Expect = 4e-05
Identities = 29/74 (39%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 168 RASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGG--GGGSSSGSSGGG--GGSGSGS 223
R+ G GGGG G S+ + GG GG GG S GSSGGG GGS G
Sbjct: 15 RSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGY 74
Query: 224 GGSSSSSSSSSKKS 237
GG S + S
Sbjct: 75 GGLGGFGGGSFRGS 88
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/43 (51%), Positives = 22/43 (51%)
Query: 189 LHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSS 231
L G S GG GGG GG G S GGG SG G GG SS
Sbjct: 453 LEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSS 495
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/56 (48%), Positives = 28/56 (50%), Gaps = 8/56 (14%)
Query: 185 SNAHLHGGASVPPGGLGGGGGGG--------SSSGSSGGGGGSGSGSGGSSSSSSS 232
S+ H S GG GG GGGG SS GS GGG SG SGGS S SS
Sbjct: 7 SSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSS 62
Score = 35.8 bits (81), Expect = 0.066
Identities = 18/29 (62%), Positives = 18/29 (62%)
Query: 208 SSSGSSGGGGGSGSGSGGSSSSSSSSSKK 236
SSS S GGGGG G G GG SS SS K
Sbjct: 12 SSSRSGGGGGGGGCGGGGGVSSLRISSSK 40
Score = 32.3 bits (72), Expect = 0.73
Identities = 17/30 (56%), Positives = 17/30 (56%)
Query: 208 SSSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
SS GGGGG G GG SS SSSK S
Sbjct: 13 SSRSGGGGGGGGCGGGGGVSSLRISSSKGS 42
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 72.0 bits (175), Expect = 8e-13
Identities = 67/207 (32%), Positives = 83/207 (40%), Gaps = 32/207 (15%)
Query: 39 PPGMDLSLA----PPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGG 94
PPG S A PP E E A+ E LL GGS G GGGG
Sbjct: 21 PPGSPGSAARGRAEPPEEEEEEEEEE-----EEAEAEAVAALLL-----NGGSGGGGGGG 70
Query: 95 GGGVGVPGLLVGSAGVGGDPSLSSLP-AGAALCLKYGESASRGSVAESSGGEQSPDDDSD 153
GGGVG G A +PS S AG + + + S GGE+ +S
Sbjct: 71 GGGVGG-----GEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAES- 124
Query: 154 GRCELVLRAGVADP----RASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSS 209
LV +G + SPGA + +G G P G GGGGGG SS
Sbjct: 125 ----LVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKG---PRGSQGGGGGGSSS 177
Query: 210 SGSSGGGGGSGSGSGGSSSSSSSSSKK 236
S GG G G+GG SS++S ++
Sbjct: 178 SSVVSSGGDEGYGTGGGGSSATSGGRR 204
Score = 32.7 bits (73), Expect = 0.56
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 7/41 (17%)
Query: 200 LGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ 240
L GG GGG GGGGG G G GG + + S S +S Q
Sbjct: 59 LNGGSGGG------GGGGGGGVG-GGEAETMSEPSPESASQ 92
Score = 32.3 bits (72), Expect = 0.73
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 201 GGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQK 241
GG GGGG G GGG + + S S S+S + + E++
Sbjct: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEE 101
Score = 32.0 bits (71), Expect = 0.95
Identities = 31/127 (24%), Positives = 45/127 (35%), Gaps = 31/127 (24%)
Query: 116 LSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGG 175
LS LP G+ SA+RG E+ +++ + E VA + G+GG
Sbjct: 17 LSPLPPGSP------GSAARGRAEPPEEEEEEEEEEEEAEAE-----AVAALLLNGGSGG 65
Query: 176 GGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSK 235
GG GG GGG GGG + S S S +G +
Sbjct: 66 GG--------------------GGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEE 105
Query: 236 KSKEQKA 242
+ E +
Sbjct: 106 EEDESSS 112
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 72.0 bits (175), Expect = 8e-13
Identities = 67/207 (32%), Positives = 83/207 (40%), Gaps = 32/207 (15%)
Query: 39 PPGMDLSLA----PPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGG 94
PPG S A PP E E A+ E LL GGS G GGGG
Sbjct: 21 PPGSPGSAARGRAEPPEEEEEEEEEE-----EEAEAEAVAALLL-----NGGSGGGGGGG 70
Query: 95 GGGVGVPGLLVGSAGVGGDPSLSSLP-AGAALCLKYGESASRGSVAESSGGEQSPDDDSD 153
GGGVG G A +PS S AG + + + S GGE+ +S
Sbjct: 71 GGGVGG-----GEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAES- 124
Query: 154 GRCELVLRAGVADP----RASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSS 209
LV +G + SPGA + +G G P G GGGGGG SS
Sbjct: 125 ----LVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKG---PRGSQGGGGGGSSS 177
Query: 210 SGSSGGGGGSGSGSGGSSSSSSSSSKK 236
S GG G G+GG SS++S ++
Sbjct: 178 SSVVSSGGDEGYGTGGGGSSATSGGRR 204
Score = 32.7 bits (73), Expect = 0.56
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 7/41 (17%)
Query: 200 LGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ 240
L GG GGG GGGGG G G GG + + S S +S Q
Sbjct: 59 LNGGSGGG------GGGGGGGVG-GGEAETMSEPSPESASQ 92
Score = 32.3 bits (72), Expect = 0.73
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 201 GGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQK 241
GG GGGG G GGG + + S S S+S + + E++
Sbjct: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEE 101
Score = 32.0 bits (71), Expect = 0.95
Identities = 31/127 (24%), Positives = 45/127 (35%), Gaps = 31/127 (24%)
Query: 116 LSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGG 175
LS LP G+ SA+RG E+ +++ + E VA + G+GG
Sbjct: 17 LSPLPPGSP------GSAARGRAEPPEEEEEEEEEEEEAEAE-----AVAALLLNGGSGG 65
Query: 176 GGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSK 235
GG GG GGG GGG + S S S +G +
Sbjct: 66 GG--------------------GGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEE 105
Query: 236 KSKEQKA 242
+ E +
Sbjct: 106 EEDESSS 112
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 71.2 bits (173), Expect = 1e-12
Identities = 60/202 (29%), Positives = 83/202 (41%), Gaps = 27/202 (13%)
Query: 49 PPRERPASSSSSPLGCFEPADPEGAGLLLPP------------PGGGGGGSAGSGGGGGG 96
P E+P + ADP G LL P P GG G G G
Sbjct: 94 PDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQ 153
Query: 97 G--VGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDG 154
V VPG G G P ++ G+A G G + GG+QSP
Sbjct: 154 QPPVAVPG---GGGGPAAVPEFNNY-YGSAAPASGGPGGRAGPCFDQHGGQQSPGMG--- 206
Query: 155 RCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHL--HGGASVPPGGLGGGGGGGSSSGS 212
++ + A +PG+ + EG N+ + G S P G GGGGGGG GS
Sbjct: 207 ----MMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262
Query: 213 SGGGGGSGSGSGGSSSSSSSSS 234
GGGGG G+G+GG+ + + +++
Sbjct: 263 GGGGGGGGAGAGGAGAGAVAAA 284
Score = 62.8 bits (151), Expect = 5e-10
Identities = 75/246 (30%), Positives = 94/246 (38%), Gaps = 51/246 (20%)
Query: 28 SKRLEAAFRSTPPGMDLSLAPPPRERPASSSSSPLGCFEPA----DPEGAGLL---LPP- 79
+K A ++ PPG PP +P +P EPA + G G L PP
Sbjct: 104 AKDSAAGGQADPPG------PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPV 157
Query: 80 --PGGGGG-----------GSAGSGGGGGGGVGVPGLLVG----SAGVGGDPSLSSLPAG 122
PGGGGG GSA GG GG P S G+G S S+ AG
Sbjct: 158 AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217
Query: 123 AALCLKYGESASRG---SVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAK 179
A + +++ G S G P G G S G GGGG
Sbjct: 218 APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGG------GGGGGGGGSGGGGGGGGA 271
Query: 180 AAEGCSN---AHLHGGASVPPGGLGGGGGGGSSSG--------SSGGGGGSGSGSGGSSS 228
A G A A+ GG GGGG GGSS+G GGG G G GG++S
Sbjct: 272 GAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAAS 331
Query: 229 SSSSSS 234
S +++
Sbjct: 332 LSKAAA 337
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/158 (30%), Positives = 59/158 (37%), Gaps = 10/158 (6%)
Query: 40 PGMDLSLAPPPRERPASSSSSPLGCFEPADPEGA-----GLLLPPPGGGGGGSAGSGGGG 94
PGM + + A S PL P G P GGGGGG G GGG
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262
Query: 95 GGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDG 154
GGG G G G AG G ++++ A AA G G + G SP G
Sbjct: 263 GGGGGGGGAGAGGAGAG---AVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 155 RCELVLRAGVAD-PRASPGAGGGGAKAAEGCSNAHLHG 191
G A +A+ G+ GG + G N H G
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAG-QNQHPSG 356
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 71.2 bits (173), Expect = 1e-12
Identities = 60/202 (29%), Positives = 83/202 (41%), Gaps = 27/202 (13%)
Query: 49 PPRERPASSSSSPLGCFEPADPEGAGLLLPP------------PGGGGGGSAGSGGGGGG 96
P E+P + ADP G LL P P GG G G G
Sbjct: 94 PDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQ 153
Query: 97 G--VGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDG 154
V VPG G G P ++ G+A G G + GG+QSP
Sbjct: 154 QPPVAVPG---GGGGPAAVPEFNNY-YGSAAPASGGPGGRAGPCFDQHGGQQSPGMG--- 206
Query: 155 RCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHL--HGGASVPPGGLGGGGGGGSSSGS 212
++ + A +PG+ + EG N+ + G S P G GGGGGGG GS
Sbjct: 207 ----MMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262
Query: 213 SGGGGGSGSGSGGSSSSSSSSS 234
GGGGG G+G+GG+ + + +++
Sbjct: 263 GGGGGGGGAGAGGAGAGAVAAA 284
Score = 62.8 bits (151), Expect = 5e-10
Identities = 75/246 (30%), Positives = 94/246 (38%), Gaps = 51/246 (20%)
Query: 28 SKRLEAAFRSTPPGMDLSLAPPPRERPASSSSSPLGCFEPA----DPEGAGLL---LPP- 79
+K A ++ PPG PP +P +P EPA + G G L PP
Sbjct: 104 AKDSAAGGQADPPG------PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPV 157
Query: 80 --PGGGGG-----------GSAGSGGGGGGGVGVPGLLVG----SAGVGGDPSLSSLPAG 122
PGGGGG GSA GG GG P S G+G S S+ AG
Sbjct: 158 AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217
Query: 123 AALCLKYGESASRG---SVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAK 179
A + +++ G S G P G G S G GGGG
Sbjct: 218 APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGG------GGGGGGGGSGGGGGGGGA 271
Query: 180 AAEGCSN---AHLHGGASVPPGGLGGGGGGGSSSG--------SSGGGGGSGSGSGGSSS 228
A G A A+ GG GGGG GGSS+G GGG G G GG++S
Sbjct: 272 GAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAAS 331
Query: 229 SSSSSS 234
S +++
Sbjct: 332 LSKAAA 337
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/158 (30%), Positives = 59/158 (37%), Gaps = 10/158 (6%)
Query: 40 PGMDLSLAPPPRERPASSSSSPLGCFEPADPEGA-----GLLLPPPGGGGGGSAGSGGGG 94
PGM + + A S PL P G P GGGGGG G GGG
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262
Query: 95 GGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDG 154
GGG G G G AG G ++++ A AA G G + G SP G
Sbjct: 263 GGGGGGGGAGAGGAGAG---AVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 155 RCELVLRAGVAD-PRASPGAGGGGAKAAEGCSNAHLHG 191
G A +A+ G+ GG + G N H G
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAG-QNQHPSG 356
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 71.2 bits (173), Expect = 1e-12
Identities = 60/202 (29%), Positives = 83/202 (41%), Gaps = 27/202 (13%)
Query: 49 PPRERPASSSSSPLGCFEPADPEGAGLLLPP------------PGGGGGGSAGSGGGGGG 96
P E+P + ADP G LL P P GG G G G
Sbjct: 94 PDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQ 153
Query: 97 G--VGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDG 154
V VPG G G P ++ G+A G G + GG+QSP
Sbjct: 154 QPPVAVPG---GGGGPAAVPEFNNY-YGSAAPASGGPGGRAGPCFDQHGGQQSPGMG--- 206
Query: 155 RCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHL--HGGASVPPGGLGGGGGGGSSSGS 212
++ + A +PG+ + EG N+ + G S P G GGGGGGG GS
Sbjct: 207 ----MMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262
Query: 213 SGGGGGSGSGSGGSSSSSSSSS 234
GGGGG G+G+GG+ + + +++
Sbjct: 263 GGGGGGGGAGAGGAGAGAVAAA 284
Score = 62.8 bits (151), Expect = 5e-10
Identities = 75/246 (30%), Positives = 94/246 (38%), Gaps = 51/246 (20%)
Query: 28 SKRLEAAFRSTPPGMDLSLAPPPRERPASSSSSPLGCFEPA----DPEGAGLL---LPP- 79
+K A ++ PPG PP +P +P EPA + G G L PP
Sbjct: 104 AKDSAAGGQADPPG------PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPV 157
Query: 80 --PGGGGG-----------GSAGSGGGGGGGVGVPGLLVG----SAGVGGDPSLSSLPAG 122
PGGGGG GSA GG GG P S G+G S S+ AG
Sbjct: 158 AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAG 217
Query: 123 AALCLKYGESASRG---SVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAK 179
A + +++ G S G P G G S G GGGG
Sbjct: 218 APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGG------GGGGGGGGSGGGGGGGGA 271
Query: 180 AAEGCSN---AHLHGGASVPPGGLGGGGGGGSSSG--------SSGGGGGSGSGSGGSSS 228
A G A A+ GG GGGG GGSS+G GGG G G GG++S
Sbjct: 272 GAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAAS 331
Query: 229 SSSSSS 234
S +++
Sbjct: 332 LSKAAA 337
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/158 (30%), Positives = 59/158 (37%), Gaps = 10/158 (6%)
Query: 40 PGMDLSLAPPPRERPASSSSSPLGCFEPADPEGA-----GLLLPPPGGGGGGSAGSGGGG 94
PGM + + A S PL P G P GGGGGG G GGG
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262
Query: 95 GGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDG 154
GGG G G G AG G ++++ A AA G G + G SP G
Sbjct: 263 GGGGGGGGAGAGGAGAG---AVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 155 RCELVLRAGVAD-PRASPGAGGGGAKAAEGCSNAHLHG 191
G A +A+ G+ GG + G N H G
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAG-QNQHPSG 356
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 70.1 bits (170), Expect = 3e-12
Identities = 54/156 (34%), Positives = 60/156 (38%), Gaps = 23/156 (14%)
Query: 82 GGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAES 141
GG GGS G GG GGG G G GS G G S S +G YG + G S
Sbjct: 491 GGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGG----YGGGSGGGHSGGS 546
Query: 142 SGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLG 201
GG + G G S G GGG+ + G +H G
Sbjct: 547 GGGHSGGSGGNYG-------GGSGSGGGSGGGYGGGSGSRGGSGGSH------------G 587
Query: 202 GGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
GG G G SG S GGG SGSGG S S S
Sbjct: 588 GGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623
Score = 68.9 bits (167), Expect = 7e-12
Identities = 60/173 (34%), Positives = 67/173 (38%), Gaps = 30/173 (17%)
Query: 66 EPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAAL 125
E + GAG + GG GGS G G GG G GS G GG
Sbjct: 463 EDFESSGAGKIGLGGRGGSGGSYGRGSRGGSG--------GSYGGGGSGGGYG------- 507
Query: 126 CLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCS 185
G S SRG S GG S G G G GGG G +
Sbjct: 508 ----GGSGSRGGSGGSYGGGSGSGGGSGGGY------GGGSGGGHSGGSGGGHSGGSGGN 557
Query: 186 NAHLHGGASVPPGGLGGGGGGGS-SSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
+GG S GG GGG GGGS S G SGG G GSG GG S S +++
Sbjct: 558 ----YGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEA 606
Score = 66.6 bits (161), Expect = 3e-11
Identities = 59/173 (34%), Positives = 71/173 (41%), Gaps = 40/173 (23%)
Query: 81 GGGGGGSAGSGGG-----------GGGGVGVPGLLVGSAGVGGDPS-LSSLPAGAALCLK 128
GGGGGG GSGG GGGG G G S+G GG S + G +
Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGG--GRFSSSSGYGGGSSRVCGRGGGGSFGYS 72
Query: 129 YGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAH 188
YG + G A S GG R GA GGG ++ G
Sbjct: 73 YGGGSGGGFSASSLGGGFG-----------------GGSRGFGGASGGGYSSSGGFG--- 112
Query: 189 LHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQK 241
GG GG GGG GGG SG GG GG G G+GG ++++KS Q+
Sbjct: 113 --GGFG---GGSGGGFGGGYGSG-FGGFGGFGGGAGGGDGGILTANEKSTMQE 159
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/93 (38%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 143 GGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGG 202
GG++ + G+ L R G GG G G S +GG S GG GG
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGG-YGGGSGSRGGSGG 518
Query: 203 GGGGGSSSGS-SGGGGGSGSGSGGSSSSSSSSS 234
GGGS SG SGGG G GSG G S S S
Sbjct: 519 SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/61 (45%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 170 SPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGS----GSGSGG 225
S GGGG G S + S GGGGGGG S SSG GGGS G G GG
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFS----SSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG 67
Query: 226 S 226
S
Sbjct: 68 S 68
Score = 37.4 bits (85), Expect = 0.023
Identities = 41/147 (27%), Positives = 44/147 (29%), Gaps = 71/147 (48%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
GG GGS G+ GGG G G GS G G G S SRG
Sbjct: 548 GGHSGGSGGNYGGGSGSGG------GSGGGYG-----------------GGSGSRGGSGG 584
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGL 200
S GG G+G GG
Sbjct: 585 SHGG---------------------------GSGFGGES--------------------- 596
Query: 201 GGGGGGGSSSGSSGGGGGSGSGSGGSS 227
GG GGG + SGGG G GSG S
Sbjct: 597 GGSYGGGEEASGSGGGYGGGSGKSSHS 623
Score = 34.7 bits (78), Expect = 0.15
Identities = 24/52 (46%), Positives = 27/52 (51%), Gaps = 8/52 (15%)
Query: 185 SNAHLHGGASVPPGGLGGGGGGGSS----SGSSGGGGG----SGSGSGGSSS 228
S+++L GGLG GG SS S S GGGGG S SG GG SS
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSS 58
Score = 32.3 bits (72), Expect = 0.73
Identities = 16/25 (64%), Positives = 16/25 (64%)
Query: 213 SGGGGGSGSGSGGSSSSSSSSSKKS 237
SGGGGG G GSGGS SS S S
Sbjct: 14 SGGGGGGGLGSGGSIRSSYSRFSSS 38
>gi|24432032 zinc finger protein 503 [Homo sapiens]
Length = 646
Score = 68.6 bits (166), Expect = 9e-12
Identities = 60/177 (33%), Positives = 73/177 (41%), Gaps = 30/177 (16%)
Query: 65 FEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVP--GLLVGSAGVGGDPSLSSLPAG 122
F+P G+ P GGGGG G GGGGGGGV G V SA + P+
Sbjct: 175 FKPYSKPGSDKKEP---GGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSS 231
Query: 123 AALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAE 182
+A + S G + S+GG DD D G G G +AE
Sbjct: 232 SA------SACSPGGMLSSAGGAPEGKDDKK------------DTDVGGGGKGTGGASAE 273
Query: 183 GCSNAHLHG------GASVPPGGLGGGGGGGSSSGSS-GGGGGSGSGSGGSSSSSSS 232
G HG G +V GG GG + GS GG GS SGSG S+ +SSS
Sbjct: 274 GGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSS 330
Score = 39.3 bits (90), Expect = 0.006
Identities = 51/196 (26%), Positives = 60/196 (30%), Gaps = 57/196 (29%)
Query: 87 SAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAA---------------------- 124
S G GGGGGGG P +G P S PAG+
Sbjct: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIK 75
Query: 125 ----LCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRA------GVADPRASP--- 171
L + G + SP + + L L A G DP S
Sbjct: 76 VLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLS 135
Query: 172 -------GAGGGGAKAAEG---------CSNAHLHGGASVPPGGLGG------GGGGGSS 209
GAGG G AA S+ + +S P G GGGGG
Sbjct: 136 SVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGG 195
Query: 210 SGSSGGGGGSGSGSGG 225
G GGGGG S G
Sbjct: 196 GGGGGGGGGVSSEKSG 211
Score = 38.9 bits (89), Expect = 0.008
Identities = 46/138 (33%), Positives = 56/138 (40%), Gaps = 43/138 (31%)
Query: 113 DPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVAD-----P 167
DPS SS K AS G A +GG + D D+ + GV D P
Sbjct: 127 DPSPSS---------KLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKP 177
Query: 168 RASPGA-----GGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGS- 221
+ PG+ GGGG GG GG GGGGGGG SS SG S +
Sbjct: 178 YSKPGSDKKEPGGGG-------------GG-----GGGGGGGGGGVSSEKSGFRVPSATC 219
Query: 222 -----GSGGSSSSSSSSS 234
+G SSS+S+ S
Sbjct: 220 QPFTPRTGSPSSSASACS 237
Score = 34.3 bits (77), Expect = 0.19
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 198 GGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSS 233
GG GGGGGGG+ + G+ SG G SS + S+
Sbjct: 18 GGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
Score = 32.0 bits (71), Expect = 0.95
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 5/37 (13%)
Query: 198 GGLGGGGGGGS-----SSGSSGGGGGSGSGSGGSSSS 229
GG GGGGGGG +S SG G G GS + S+
Sbjct: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
Score = 31.6 bits (70), Expect = 1.2
Identities = 16/38 (42%), Positives = 20/38 (52%)
Query: 199 GLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKK 236
G GGGGGGG + + SG+ SG SS + S K
Sbjct: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTK 54
Score = 29.3 bits (64), Expect = 6.2
Identities = 14/29 (48%), Positives = 17/29 (58%)
Query: 209 SSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
SS SGGGGG G G G + +S+ S S
Sbjct: 12 SSKHSGGGGGGGGGGGADPAWTSALSGNS 40
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 68.2 bits (165), Expect = 1e-11
Identities = 73/254 (28%), Positives = 99/254 (38%), Gaps = 31/254 (12%)
Query: 2 ERGMHLGAAAAGEDD-LFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPASSSSS 60
E+ HL A GED+ LF + ++ S E S + L P R + S
Sbjct: 378 EQFCHLRAIGDGEDEMLFTRRFVTPS-----EPVAHSRRGRLHL----PRGRRSRRAVSV 428
Query: 61 PLGCFEPADPEGAGLLLPPPGGGGGGS-----AGSGGGGGGGVGVPGLLVGSAGVGGD-P 114
P F P A P G +GSG G G G P G GGD
Sbjct: 429 PASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYM 488
Query: 115 SLSSLPAGAALCLKYGESAS-RGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGA 173
+++ +G G+ ++ +GS + SSGG Q + R + S G
Sbjct: 489 PMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSR----------GGQGSNGQ 538
Query: 174 GGGG---AKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSS 230
G GG ++ +G + H GG P GG G GGG G G G GGG SG G S S
Sbjct: 539 GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDG-HGSGGGKNSGGGKGSGSG 597
Query: 231 SSSSKKSKEQKALR 244
S + K+L+
Sbjct: 598 KGSDGDGERGKSLK 611
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 66.6 bits (161), Expect = 3e-11
Identities = 57/158 (36%), Positives = 59/158 (37%), Gaps = 41/158 (25%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
GG GG G G GG G G GS G GG G S GS
Sbjct: 515 GGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGR--------------GSYGSGGSSYG 560
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGL 200
S GG S G GGG G S+ GG+ GG
Sbjct: 561 SGGGSYG----------------------SGGGGGGHGSYGSGSSSGGYRGGSG---GGG 595
Query: 201 GGGGGG-GSSSGSSGGG-GGSGSGSGGSSSSSSSSSKK 236
GG GG GS GSSGG GG GS SGG SS SSS K
Sbjct: 596 GGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVK 633
Score = 55.5 bits (132), Expect = 8e-08
Identities = 45/145 (31%), Positives = 52/145 (35%), Gaps = 46/145 (31%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
GGGGG + GGGGG G+ G G SL +L ++ + RGS
Sbjct: 40 GGGGGRFSSCGGGGGS--------FGAGGGFGSRSLVNLGGSKSISISVARGGGRGS--- 88
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGL 200
G G GGGG GG GG+
Sbjct: 89 ----------------------GFGGGYGGGGFGGGG------------FGGGGFGGGGI 114
Query: 201 GGGGGGGSSSGSSGGGGGSGSGSGG 225
GGGG GG SG GG GG G G GG
Sbjct: 115 GGGGFGGFGSG-GGGFGGGGFGGGG 138
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/69 (47%), Positives = 38/69 (55%), Gaps = 4/69 (5%)
Query: 172 GAGGGGAKAAEGCS-NAHLHGGASVPPGGLGGGGGGGSSSGSSGGG--GGSGSGSGGSSS 228
G GGGG + + G +++ GG S GG GGGG G SGSS GG GGSG G GGSS
Sbjct: 542 GGGGGGGRGSYGSGGSSYGSGGGSYGSGG-GGGGHGSYGSGSSSGGYRGGSGGGGGGSSG 600
Query: 229 SSSSSSKKS 237
S S
Sbjct: 601 GRGSGGGSS 609
Score = 43.5 bits (101), Expect = 3e-04
Identities = 28/54 (51%), Positives = 30/54 (55%), Gaps = 5/54 (9%)
Query: 185 SNAHLHGGASVPPGGLGGGGGG---GSSSGS--SGGGGGSGSGSGGSSSSSSSS 233
S+ + GG S GG G G GG GS GS SGGGGG G GS GS SS S
Sbjct: 508 SHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGS 561
Score = 38.9 bits (89), Expect = 0.008
Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 8/60 (13%)
Query: 175 GGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSS 234
GGG++ G GG G GGG S G GGG GS GSGGSS S S
Sbjct: 514 GGGSRGGGG-------GGYGSGGSSYGSGGGSYGSGGGGGGGRGS-YGSGGSSYGSGGGS 565
Score = 34.3 bits (77), Expect = 0.19
Identities = 17/32 (53%), Positives = 17/32 (53%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGG 112
GGGG G G GG G GG G G G G GG
Sbjct: 110 GGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGG 141
Score = 33.9 bits (76), Expect = 0.25
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 168 RASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGG---GSSSGSSGGGGGSGSGS- 223
R+ +GGG + + G N +S GGGG G GS G GGG GS S
Sbjct: 8 RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSL 67
Query: 224 ---GGSSSSSSSSSK 235
GGS S S S ++
Sbjct: 68 VNLGGSKSISISVAR 82
Score = 33.9 bits (76), Expect = 0.25
Identities = 32/99 (32%), Positives = 34/99 (34%), Gaps = 7/99 (7%)
Query: 56 SSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPS 115
SS S G + G G GG GS G G GGG G G + GG
Sbjct: 530 SSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRG 589
Query: 116 LSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDG 154
S G G S RGS SSGG S G
Sbjct: 590 GSGGGGG-------GSSGGRGSGGGSSGGSIGGRGSSSG 621
Score = 29.3 bits (64), Expect = 6.2
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGV 110
G GGGG G G GGGG G G + G+
Sbjct: 123 GSGGGGFGGGGFGGGGYGGGYGPVCPPGGI 152
>gi|116805332 musculin [Homo sapiens]
Length = 206
Score = 66.6 bits (161), Expect = 3e-11
Identities = 56/182 (30%), Positives = 78/182 (42%), Gaps = 40/182 (21%)
Query: 130 GESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHL 189
G S S +++S E+ D + RC L G A +AEGC
Sbjct: 33 GVERSYASPSDNSSAEEEDPDGEEERCAL-----------------GTAGSAEGCKRKRP 75
Query: 190 HGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINA 249
+ GGGG G GS+GGGG + GS++ S + + NA
Sbjct: 76 R---------VAGGGGAG---GSAGGGGKKPLPAKGSAAECKQSQRNA---------ANA 114
Query: 250 RERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAY 309
RER RM L+ A L+ +P+ P KLSK+ TL LA +YI Q L+E R Y
Sbjct: 115 RERARMRVLSKAFSRLKTSLPWV--PPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGY 172
Query: 310 LN 311
++
Sbjct: 173 VH 174
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 63.9 bits (154), Expect = 2e-10
Identities = 56/158 (35%), Positives = 65/158 (41%), Gaps = 12/158 (7%)
Query: 163 GVADPRASPGAGGGGAKAAEGCSNAHLHGG-------ASVPPGGLGGGGGGGSSSGSSGG 215
G A P P G G A L G A V G GG G
Sbjct: 34 GDAPPPPPPAPGPGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGL 93
Query: 216 GGGSGSGSGGSSSSSSSSSKKSKEQKALRLN-INARERRRMHDLNDALDELRAVIPYAHS 274
G +K E+ LR NARER RMHDLN ALD LR V+P
Sbjct: 94 DEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPC--Y 151
Query: 275 PSVRKLSKIATLLLAKNYILMQAQALEEMRR--LVAYL 310
+KLSKI TL LAKNYI ++ L +R LV+Y+
Sbjct: 152 SKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYV 189
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 63.5 bits (153), Expect = 3e-10
Identities = 53/174 (30%), Positives = 64/174 (36%), Gaps = 29/174 (16%)
Query: 82 GGGGGSAGSGGGGGGGVGVP------------------GLLVGSAGVGGDPSLSSLPAGA 123
G GG G G G GG+G P G G G GG P+ + GA
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
Query: 124 ALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEG 183
YG + + + G +P G G S G+G G
Sbjct: 212 VAQPGYGSVRA----SNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDN---- 263
Query: 184 CSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
+N GG+S G GG GGSS GSSG GGS SG SS SS+ S
Sbjct: 264 -NNGSSSGGSS--SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS 314
Score = 62.8 bits (151), Expect = 5e-10
Identities = 54/166 (32%), Positives = 71/166 (42%), Gaps = 22/166 (13%)
Query: 83 GGGGSAGSGGG-GGGGVGVPGLLVGSAGVGGDP-----SLSSLPAGAALCLKYGESAS-- 134
GG G GS GG GG G G PG L G+ V G P S P GA +G+ +
Sbjct: 146 GGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSFGMNPQGAP----WGQGGNGG 200
Query: 135 --------RGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSN 186
+G+VA+ G + ++G C +G ++ G G G + G +
Sbjct: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEG-CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGS 259
Query: 187 AHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSS 232
+ S G G GGSS GSSGG G+ GS G S S SS
Sbjct: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
Score = 56.6 bits (135), Expect = 4e-08
Identities = 49/165 (29%), Positives = 63/165 (38%), Gaps = 35/165 (21%)
Query: 68 ADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCL 127
A + G PPP G GGGS+ SGGG G G G +G GD + S G++
Sbjct: 222 ASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG-----SGSNGDNNNGSSSGGSS--- 273
Query: 128 KYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNA 187
S+S GS SSGG S G G++++ G S
Sbjct: 274 --SGSSSGGSSGGSSGGSSGNSGGS--------------------RGDSGSESSWGSST- 310
Query: 188 HLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSS 232
G+S G GGG G G GSG G +S +S
Sbjct: 311 ----GSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/131 (25%), Positives = 49/131 (37%), Gaps = 15/131 (11%)
Query: 48 PPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGS 107
PPP SS+S G + G+G G G + SG GG G S
Sbjct: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-----GSS 286
Query: 108 AGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGE------QSPDDDSDGRCELVLR 161
G G+ S +G+ +S G+ S GG + P +++ G E
Sbjct: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE---- 342
Query: 162 AGVADPRASPG 172
+G+ + SPG
Sbjct: 343 SGIQNSETSPG 353
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 63.5 bits (153), Expect = 3e-10
Identities = 53/174 (30%), Positives = 64/174 (36%), Gaps = 29/174 (16%)
Query: 82 GGGGGSAGSGGGGGGGVGVP------------------GLLVGSAGVGGDPSLSSLPAGA 123
G GG G G G GG+G P G G G GG P+ + GA
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
Query: 124 ALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEG 183
YG + + + G +P G G S G+G G
Sbjct: 212 VAQPGYGSVRA----SNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDN---- 263
Query: 184 CSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
+N GG+S G GG GGSS GSSG GGS SG SS SS+ S
Sbjct: 264 -NNGSSSGGSS--SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS 314
Score = 62.8 bits (151), Expect = 5e-10
Identities = 54/166 (32%), Positives = 71/166 (42%), Gaps = 22/166 (13%)
Query: 83 GGGGSAGSGGG-GGGGVGVPGLLVGSAGVGGDP-----SLSSLPAGAALCLKYGESAS-- 134
GG G GS GG GG G G PG L G+ V G P S P GA +G+ +
Sbjct: 146 GGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSFGMNPQGAP----WGQGGNGG 200
Query: 135 --------RGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSN 186
+G+VA+ G + ++G C +G ++ G G G + G +
Sbjct: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEG-CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGS 259
Query: 187 AHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSS 232
+ S G G GGSS GSSGG G+ GS G S S SS
Sbjct: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
Score = 57.0 bits (136), Expect = 3e-08
Identities = 51/174 (29%), Positives = 67/174 (38%), Gaps = 37/174 (21%)
Query: 68 ADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCL 127
A + G PPP G GGGS+ SGGG G G G +G GD + S G++
Sbjct: 222 ASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG-----SGSNGDNNNGSSSGGSS--- 273
Query: 128 KYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNA 187
S+S GS SSGG S G G++++ G S
Sbjct: 274 --SGSSSGGSSGGSSGGSSGNSGGS--------------------RGDSGSESSWGSST- 310
Query: 188 HLHGGASVPPGGLGGGGG---GGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSK 238
G +S GG GGG G G G+ G G G SS+ + S+
Sbjct: 311 ---GSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSE 361
Score = 33.5 bits (75), Expect = 0.33
Identities = 47/186 (25%), Positives = 56/186 (30%), Gaps = 54/186 (29%)
Query: 48 PPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGS 107
PPP SS+S G + G+G G G + SG GG G G GS
Sbjct: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG--GSSGGS 289
Query: 108 AGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADP 167
+G G S G +S GS SS G
Sbjct: 290 SGNSGGSRGDS-----------GSESSWGSSTGSSSGNH--------------------- 317
Query: 168 RASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSS 227
G GGG GC PG G SG SG G G G +
Sbjct: 318 ----GGSGGGNGHKPGCEK----------PGNEARG------SGESGIQGFRGQGVSSNM 357
Query: 228 SSSSSS 233
+S +S
Sbjct: 358 RNSETS 363
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 63.5 bits (153), Expect = 3e-10
Identities = 53/174 (30%), Positives = 64/174 (36%), Gaps = 29/174 (16%)
Query: 82 GGGGGSAGSGGGGGGGVGVP------------------GLLVGSAGVGGDPSLSSLPAGA 123
G GG G G G GG+G P G G G GG P+ + GA
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
Query: 124 ALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEG 183
YG + + + G +P G G S G+G G
Sbjct: 212 VAQPGYGSVRA----SNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDN---- 263
Query: 184 CSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
+N GG+S G GG GGSS GSSG GGS SG SS SS+ S
Sbjct: 264 -NNGSSSGGSS--SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS 314
Score = 62.8 bits (151), Expect = 5e-10
Identities = 54/166 (32%), Positives = 71/166 (42%), Gaps = 22/166 (13%)
Query: 83 GGGGSAGSGGG-GGGGVGVPGLLVGSAGVGGDP-----SLSSLPAGAALCLKYGESAS-- 134
GG G GS GG GG G G PG L G+ V G P S P GA +G+ +
Sbjct: 146 GGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSFGMNPQGAP----WGQGGNGG 200
Query: 135 --------RGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSN 186
+G+VA+ G + ++G C +G ++ G G G + G +
Sbjct: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEG-CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGS 259
Query: 187 AHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSS 232
+ S G G GGSS GSSGG G+ GS G S S SS
Sbjct: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
Score = 57.0 bits (136), Expect = 3e-08
Identities = 54/170 (31%), Positives = 65/170 (38%), Gaps = 18/170 (10%)
Query: 68 ADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCL 127
A + G PPP G GGGS+ SGGG G G G +G GD + S G++
Sbjct: 222 ASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG-----SGSNGDNNNGSSSGGSS--- 273
Query: 128 KYGESASRGSVAESSGGEQSPDDDS--DGRCELVLRAGVADPRASPGAGGGGAKAAEGCS 185
S+S GS SSGG S D E + + G GGG GC
Sbjct: 274 --SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCE 331
Query: 186 NAHLHGGASVPPGGLGGGGGGGSSSG---SSGGG---GGSGSGSGGSSSS 229
S G G G G SS+ S G GGSG S +S
Sbjct: 332 KPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETS 381
Score = 33.9 bits (76), Expect = 0.25
Identities = 43/170 (25%), Positives = 61/170 (35%), Gaps = 20/170 (11%)
Query: 48 PPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGS 107
PPP SS+S G + G+G G G + SG GG G G GS
Sbjct: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG--GSSGGS 289
Query: 108 AGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADP 167
+G G S G +S GS SS G +G + G P
Sbjct: 290 SGNSGGSRGDS-----------GSESSWGSSTGSSSGNHGGSGGGNGH-----KPGCEKP 333
Query: 168 -RASPGAGGGGAKAAEGCS-NAHLHGGASVPPGGLGGGGGGGSSSGSSGG 215
+ G+G G + G ++++ + LGG G +S +S G
Sbjct: 334 GNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 63.5 bits (153), Expect = 3e-10
Identities = 53/174 (30%), Positives = 64/174 (36%), Gaps = 29/174 (16%)
Query: 82 GGGGGSAGSGGGGGGGVGVP------------------GLLVGSAGVGGDPSLSSLPAGA 123
G GG G G G GG+G P G G G GG P+ + GA
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
Query: 124 ALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEG 183
YG + + + G +P G G S G+G G
Sbjct: 212 VAQPGYGSVRA----SNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDN---- 263
Query: 184 CSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKS 237
+N GG+S G GG GGSS GSSG GGS SG SS SS+ S
Sbjct: 264 -NNGSSSGGSS--SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS 314
Score = 62.8 bits (151), Expect = 5e-10
Identities = 54/166 (32%), Positives = 71/166 (42%), Gaps = 22/166 (13%)
Query: 83 GGGGSAGSGGG-GGGGVGVPGLLVGSAGVGGDP-----SLSSLPAGAALCLKYGESAS-- 134
GG G GS GG GG G G PG L G+ V G P S P GA +G+ +
Sbjct: 146 GGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSFGMNPQGAP----WGQGGNGG 200
Query: 135 --------RGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSN 186
+G+VA+ G + ++G C +G ++ G G G + G +
Sbjct: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEG-CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGS 259
Query: 187 AHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSS 232
+ S G G GGSS GSSGG G+ GS G S S SS
Sbjct: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
Score = 56.6 bits (135), Expect = 4e-08
Identities = 49/165 (29%), Positives = 63/165 (38%), Gaps = 35/165 (21%)
Query: 68 ADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCL 127
A + G PPP G GGGS+ SGGG G G G +G GD + S G++
Sbjct: 222 ASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG-----SGSNGDNNNGSSSGGSS--- 273
Query: 128 KYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNA 187
S+S GS SSGG S G G++++ G S
Sbjct: 274 --SGSSSGGSSGGSSGGSSGNSGGS--------------------RGDSGSESSWGSST- 310
Query: 188 HLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSS 232
G+S G GGG G G GSG G +S +S
Sbjct: 311 ----GSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/131 (25%), Positives = 49/131 (37%), Gaps = 15/131 (11%)
Query: 48 PPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGS 107
PPP SS+S G + G+G G G + SG GG G S
Sbjct: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-----GSS 286
Query: 108 AGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGE------QSPDDDSDGRCELVLR 161
G G+ S +G+ +S G+ S GG + P +++ G E
Sbjct: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE---- 342
Query: 162 AGVADPRASPG 172
+G+ + SPG
Sbjct: 343 SGIQNSETSPG 353
>gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens]
Length = 1215
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/169 (32%), Positives = 77/169 (45%), Gaps = 12/169 (7%)
Query: 70 PEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAAL-CLK 128
P A L PGGGGGG SGGGGG G G GG + ++ GAAL L
Sbjct: 8 PPPAKRLCCRPGGGGGGGGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALGLLP 67
Query: 129 YGESASRGS---VAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCS 185
G++ S S +A E+ P + R E + R + + S
Sbjct: 68 PGKTQSPESLLDIAARRVAEKWPFQRVEERFERIPEP--VQRRIVYWSFPRSEREICMYS 125
Query: 186 NAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSS 234
+ + GGA+ PG GGGGG +GGGGG GS S +++S++++S
Sbjct: 126 SFNTGGGAAGGPGDDSGGGGG------AGGGGGGGSSSSPAATSAAATS 168
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
GGG G G GGGGG G G S+ + ++ A AA +A+ G+ A
Sbjct: 130 GGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAAAGAGAP 189
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVA 165
S G + D + R L R G+A
Sbjct: 190 SVGAAGAADGGDETR--LPFRRGIA 212
Score = 38.1 bits (87), Expect = 0.013
Identities = 49/195 (25%), Positives = 77/195 (39%), Gaps = 23/195 (11%)
Query: 171 PGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSS 230
PG GGGG GG+S GG GGG G GG + + GG ++
Sbjct: 18 PGGGGGG-------------GGSSGGGGGAGGGYSSACRPGPRAGGAAAAAACGGGAALG 64
Query: 231 SSSSKKSKEQKALRLNINARE------RRRMHDLNDALDE--LRAVIPYAHSPSVRKLSK 282
K++ ++L L+I AR +R+ + + + E R ++ ++ S R++
Sbjct: 65 LLPPGKTQSPESL-LDIAARRVAEKWPFQRVEERFERIPEPVQRRIVYWSFPRSEREICM 123
Query: 283 IATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYE 342
++ G + S A+ ++A +AAAAAA A A
Sbjct: 124 YSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAAAAAAAAAAA 183
Query: 343 QAAGYPFSAGLPPAA 357
AG P S G AA
Sbjct: 184 AGAGAP-SVGAAGAA 197
Score = 36.2 bits (82), Expect = 0.050
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 64 CFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGA 123
C + G G P GGG GGGGGG P SA + ++ A A
Sbjct: 122 CMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPA--ATSAAATSAAAAAAAAAAA 179
Query: 124 ALCLKYGESASRGSVAESSGGEQS 147
A + S G+ + GG+++
Sbjct: 180 AAAAAGAGAPSVGAAGAADGGDET 203
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 63.2 bits (152), Expect = 4e-10
Identities = 50/143 (34%), Positives = 64/143 (44%), Gaps = 24/143 (16%)
Query: 107 SAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVAD 166
S+ V + S++ + A +G S RGS SSGG S S G +G
Sbjct: 496 SSNVTVSVTSSTISSNVASKAAFGGSGGRGS---SSGGGYSSGSSSYG-------SGGRQ 545
Query: 167 PRASPGAGGGGAKAAEGCSNAHLHGG----------ASVPPGGLGGGGG----GGSSSGS 212
+ G+GGGG+ + G + GG S+ GG G GGG GG S G
Sbjct: 546 SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGG 605
Query: 213 SGGGGGSGSGSGGSSSSSSSSSK 235
S GGG GSG GGSSS SS +
Sbjct: 606 SSSGGGYGSGGGGSSSVKGSSGE 628
Score = 57.0 bits (136), Expect = 3e-08
Identities = 57/196 (29%), Positives = 70/196 (35%), Gaps = 36/196 (18%)
Query: 87 SAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQ 146
S S G GGGG G G GSA V G S+ +S ++ GG
Sbjct: 6 SCKSRGRGGGGGGFRGFSSGSAVVSGGSRRST--------------SSFSCLSRHGGGGG 51
Query: 147 SPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSN--------AHLHGGASVPPG 198
G LV G S GGGG AA G + GG+ G
Sbjct: 52 GFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGG 111
Query: 199 GLGGGGGGGSSSGSSGGGGG----SGSGSGGSSSSSSSSSKKSKEQKALR---------- 244
G GGGG GG G GG GG G G G + S Q L+
Sbjct: 112 GFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEI 171
Query: 245 LNINARERRRMHDLND 260
N+ A+ER ++ LN+
Sbjct: 172 QNVKAQEREQIKTLNN 187
Score = 46.2 bits (108), Expect = 5e-05
Identities = 54/158 (34%), Positives = 58/158 (36%), Gaps = 48/158 (30%)
Query: 81 GGGGGGSAGSGGG---GGGGVGVPGLLVGS-AGVGGDPSLSSLPAGAALCLKYGESASR- 135
GG GG + SGGG G G G GS G GG S+S G+ G S R
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSG-----GGSGGRY 573
Query: 136 GSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASV 195
GS S GG S G G GG K H GG S
Sbjct: 574 GSGGGSKGGSIS----------------------GGGYGSGGGK--------HSSGGGS- 602
Query: 196 PPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSS 233
GG GGG GS GGGGS S G S + SS
Sbjct: 603 -RGGSSSGGGYGS------GGGGSSSVKGSSGEAFGSS 633
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/148 (31%), Positives = 53/148 (35%), Gaps = 29/148 (19%)
Query: 83 GGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESS 142
GG G GS GGG G S G GG S S G S GS+ S
Sbjct: 519 GGSGGRGSSSGGGYSSGS-----SSYGSGGRQSGSR-----------GGSGGGGSI---S 559
Query: 143 GGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGG 202
GG S GR +G S GG G+ + S GG+S G
Sbjct: 560 GGGYGSGGGSGGR----YGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSS------SG 609
Query: 203 GGGGGSSSGSSGGGGGSGSGSGGSSSSS 230
GG G GSS G SG G S + S
Sbjct: 610 GGYGSGGGGSSSVKGSSGEAFGSSVTFS 637
Score = 35.0 bits (79), Expect = 0.11
Identities = 17/31 (54%), Positives = 18/31 (58%)
Query: 82 GGGGGSAGSGGGGGGGVGVPGLLVGSAGVGG 112
GGG G G GGG GG G PG + G G GG
Sbjct: 110 GGGFGGGGFGGGRFGGFGGPGGVGGLGGPGG 140
Score = 34.3 bits (77), Expect = 0.19
Identities = 18/32 (56%), Positives = 18/32 (56%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGG 112
GGG G S G GGGG G G G G GVGG
Sbjct: 103 GGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGG 134
Score = 33.9 bits (76), Expect = 0.25
Identities = 16/32 (50%), Positives = 18/32 (56%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGG 112
GGGG G+AG GG GGG G G +G G
Sbjct: 79 GGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSG 110
Score = 32.7 bits (73), Expect = 0.56
Identities = 17/37 (45%), Positives = 19/37 (51%)
Query: 208 SSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALR 244
+S + GG GG GS SGG SS SSS Q R
Sbjct: 513 ASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSR 549
Score = 31.2 bits (69), Expect = 1.6
Identities = 15/31 (48%), Positives = 15/31 (48%)
Query: 82 GGGGGSAGSGGGGGGGVGVPGLLVGSAGVGG 112
GG GG G G GGG G G G G GG
Sbjct: 90 GGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120
Score = 30.4 bits (67), Expect = 2.8
Identities = 20/49 (40%), Positives = 20/49 (40%)
Query: 63 GCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPGLLVGSAGVG 111
G F G G G GGGG G GG GG G G L G G G
Sbjct: 94 GGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFG 142
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 62.8 bits (151), Expect = 5e-10
Identities = 66/209 (31%), Positives = 83/209 (39%), Gaps = 37/209 (17%)
Query: 197 PGGLGGGGGGGSSSGSSGGGGGSGSGSGG-----------------SSSSSSSSSKKSKE 239
PG GG + G GG +G+ G S + + S K+ E
Sbjct: 45 PGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAE 104
Query: 240 -----QKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYIL 294
+K RL N RER RMH+LN ALD LR V+P P KL+KI TL A NYI
Sbjct: 105 TVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP--TFPEDAKLTKIETLRFAHNYI- 161
Query: 295 MQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLP 354
AL E RL + G LP + + A + A A + P A
Sbjct: 162 ---WALTETLRLADHCGGG----GGGLPGALFSEAVLLSPGGASAALSSSGDSPSPAS-- 212
Query: 355 PAASCPEKCALFNSVSSSLCK--QCTEKP 381
SC A +SVSS+ CT P
Sbjct: 213 -TWSCTNSPAPSSSVSSNSTSPYSCTLSP 240
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 62.4 bits (150), Expect = 7e-10
Identities = 53/140 (37%), Positives = 63/140 (45%), Gaps = 33/140 (23%)
Query: 161 RAGVADPRASPGAG-------GGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSS 213
RA V D A+PG G G + A+G + A P G G G S
Sbjct: 11 RAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAP------GEGRRRRPGPS 64
Query: 214 GGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAH 273
G GG + S Q+ RL N RER+RMH LN+A LR VIP H
Sbjct: 65 GPGG----------------RRDSSIQR--RLESNERERQRMHKLNNAFQALREVIP--H 104
Query: 274 SPSVRKLSKIATLLLAKNYI 293
+ +KLSKI TL LAKNYI
Sbjct: 105 VRADKKLSKIETLTLAKNYI 124
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 62.0 bits (149), Expect = 9e-10
Identities = 60/165 (36%), Positives = 74/165 (44%), Gaps = 27/165 (16%)
Query: 205 GGGSSSGSSGG-----------GGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERR 253
GG SSS S G GG G S + SS + + QK RL NARERR
Sbjct: 111 GGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERR 170
Query: 254 RMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQG 313
RMH LN A D+LR VIP ++ +KLSK TL +A+ YI AL E+
Sbjct: 171 RMHGLNHAFDQLRNVIPSFNND--KKLSKYETLQMAQIYI----NALSELL--------- 215
Query: 314 QAISAASLPSSAAAAAAAAALHPALGA-YEQAAGYPFSAGLPPAA 357
Q S P A+ + H A YE AG +AG A+
Sbjct: 216 QTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQAS 260
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/273 (26%), Positives = 90/273 (32%), Gaps = 61/273 (22%)
Query: 32 EAAFRSTPPGMDLSLAPPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSG 91
EAA +T + PP E P S P EP PP G GGG G G
Sbjct: 125 EAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEP-----------PPLGEGGGGGGEG 173
Query: 92 GGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDD 151
GG GGG G GG P P G A + + G SP
Sbjct: 174 GGAGGGSG--------EREGGAPQ----PPPPRGWRGKGVRAQQRGGSGGEGASPSPSSS 221
Query: 152 SDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHL--------HGGASVPPGGLGGG 203
S G+ A G+GGGG+ EGC + L A+ +
Sbjct: 222 SAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAK 281
Query: 204 GGGGSSSGSSGGGG--------------------------GSGSGSGGSSSSSSSSSKKS 237
GGGSSS SS G GS SGG +++ S +
Sbjct: 282 NGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQP 341
Query: 238 KEQKALRLNINARERRRMHDLNDAL----DELR 266
Q+ E ++ + N+ L DELR
Sbjct: 342 HPQQLQEQEEMQEEMEKLREENETLKNEIDELR 374
Score = 52.0 bits (123), Expect = 9e-07
Identities = 69/273 (25%), Positives = 93/273 (34%), Gaps = 48/273 (17%)
Query: 81 GGGGGGSAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAE 140
G G A GGGGG L A G P AGA E+A ++A
Sbjct: 86 GSRTGPPASIRGGGGGAEKATPL----APKGAAPGAVQPVAGA-------EAAPAATLAA 134
Query: 141 SSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPP--- 197
G P ++ E V P G GGGG G + GGA PP
Sbjct: 135 LGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGSGEREGGAPQPPPPR 194
Query: 198 ------------GGLGGGGGGGSSSGSSGG--------GGGSGSGSGGSSSSSSSSSKKS 237
GG GG G S S SS G GSG GGS S +
Sbjct: 195 GWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGC 254
Query: 238 KEQKALRLNIN------ARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKN 291
+ + ++ ++ A +MH N R+ P + P+V + +A+
Sbjct: 255 LQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRS-SPVSGPPAVCETLAVAS------ 307
Query: 292 YILMQAQALEEMRRLVAYLNQGQAISAASLPSS 324
A A E ++ G + AA+ PSS
Sbjct: 308 -ASPMAAAAEGPQQSAEGSASGGGMQAAAPPSS 339
>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
Length = 331
Score = 60.5 bits (145), Expect = 2e-09
Identities = 34/61 (55%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 241 KALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 300
+A R+ NARER RMH LNDALD LR V+P +KLSKI TL LA+NYI ++ L
Sbjct: 86 RARRVKANARERTRMHGLNDALDNLRRVMPC--YSKTQKLSKIETLRLARNYIWALSEVL 143
Query: 301 E 301
E
Sbjct: 144 E 144
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.129 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,826,645
Number of Sequences: 37866
Number of extensions: 1276253
Number of successful extensions: 50681
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 850
Number of HSP's successfully gapped in prelim test: 806
Number of HSP's that attempted gapping in prelim test: 13064
Number of HSP's gapped (non-prelim): 15498
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.