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Search of human proteins with 226342935
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
(421 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 850 0.0
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 614 e-176
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 602 e-172
gi|45505137 podocan [Homo sapiens] 294 1e-79
gi|188528675 slit homolog 1 [Homo sapiens] 121 1e-27
gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 118 1e-26
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 117 2e-26
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 117 2e-26
gi|71040111 fibromodulin precursor [Homo sapiens] 117 3e-26
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 113 4e-25
gi|4502403 biglycan preproprotein [Homo sapiens] 111 1e-24
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 110 2e-24
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 110 2e-24
gi|225579152 insulin-like growth factor binding protein, acid la... 110 3e-24
gi|4826772 insulin-like growth factor binding protein, acid labi... 110 3e-24
gi|41349454 proline arginine-rich end leucine-rich repeat protei... 110 3e-24
gi|4506041 proline arginine-rich end leucine-rich repeat protein... 110 3e-24
gi|4505047 lumican precursor [Homo sapiens] 107 2e-23
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 107 2e-23
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 107 2e-23
gi|5901992 keratocan [Homo sapiens] 106 3e-23
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 104 2e-22
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 104 2e-22
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 104 2e-22
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 102 9e-22
gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa... 101 1e-21
gi|194440719 chondroadherin-like [Homo sapiens] 101 1e-21
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 101 1e-21
gi|41350214 asporin [Homo sapiens] 100 2e-21
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ... 100 4e-21
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 850 bits (2197), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MGRPTQWPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDG 60
MGRPTQWPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDG
Sbjct: 1 MGRPTQWPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDG 60
Query: 61 LDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFES 120
LDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFES
Sbjct: 61 LDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFES 120
Query: 121 LTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 180
LTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL
Sbjct: 121 LTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 180
Query: 181 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 240
DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG
Sbjct: 181 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 240
Query: 241 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 300
ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY
Sbjct: 241 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 300
Query: 301 NRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAG 360
NRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAG
Sbjct: 301 NRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAG 360
Query: 361 LDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCLPCHVPNILVS 420
LDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCLPCHVPNILVS
Sbjct: 361 LDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCLPCHVPNILVS 420
Query: 421 W 421
W
Sbjct: 421 W 421
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 614 bits (1583), Expect = e-176
Identities = 346/510 (67%), Positives = 365/510 (71%), Gaps = 89/510 (17%)
Query: 1 MGRPTQWPSLLLLLLLPG--------------------PPPVA----------------G 24
MGRPTQWPSLLLLLLLPG P P A G
Sbjct: 1 MGRPTQWPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDG 60
Query: 25 LEDAAFP--------HLG---ESLQPLP-----RACPLRCSCPRVDTVDCDGLD------ 62
L+ FP HL LQ LP R LR + + +GL
Sbjct: 61 LDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFES 120
Query: 63 -------------LRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLIS 109
L V P + R+ + L NQ+ E+ LR++ LHNN +S
Sbjct: 121 LTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLS 180
Query: 110 SEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRGALSRQTQL 151
+ GLP +AF + L +++N+ NNLISKVPRGALSRQTQL
Sbjct: 181 NAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQL 240
Query: 152 RELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQV 211
RELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQV
Sbjct: 241 RELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQV 300
Query: 212 EAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRA 271
EAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRA
Sbjct: 301 EAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRA 360
Query: 272 LVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTR 331
LVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTR
Sbjct: 361 LVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTR 420
Query: 332 LPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 391
LPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ
Sbjct: 421 LPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 480
Query: 392 VRHRLVSHTVPRAPPSPCLPCHVPNILVSW 421
VRHRLVSHTVPRAPPSPCLPCHVPNILVSW
Sbjct: 481 VRHRLVSHTVPRAPPSPCLPCHVPNILVSW 510
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 602 bits (1551), Expect = e-172
Identities = 320/416 (76%), Positives = 335/416 (80%), Gaps = 35/416 (8%)
Query: 24 GLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQ 83
GL D AF ESL L C L V P + R+ + L NQ
Sbjct: 114 GLPDEAF----ESLTQLQHLCVAHNK-------------LSVAPQFLPRSLRVADLAANQ 156
Query: 84 LQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNK---------- 133
+ E+ LR++ LHNN +S+ GLP +AF + L +++N+
Sbjct: 157 VMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPP 216
Query: 134 --------NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHN 185
NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHN
Sbjct: 217 SLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHN 276
Query: 186 QLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPL 245
QLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPL
Sbjct: 277 QLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPL 336
Query: 246 RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS 305
RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS
Sbjct: 337 RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS 396
Query: 306 ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLR 365
ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLR
Sbjct: 397 ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLR 456
Query: 366 ELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCLPCHVPNILVSW 421
ELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCLPCHVPNILVSW
Sbjct: 457 ELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCLPCHVPNILVSW 512
Score = 392 bits (1006), Expect = e-109
Identities = 225/403 (55%), Positives = 257/403 (63%), Gaps = 18/403 (4%)
Query: 7 WPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVF 66
WPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVF
Sbjct: 9 WPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVF 68
Query: 67 PDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQH 126
PDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQH
Sbjct: 69 PDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQH 128
Query: 127 LCVAHNKNNLISK-VPRG-----------------ALSRQTQLRELYLQHNQLTDSGLDA 168
LCVAHNK ++ + +PR + LR +YL +NQL+++GL
Sbjct: 129 LCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPP 188
Query: 169 TTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQ 228
F ++ L LS+NQL+ +P LP +L LHL N I +V L LR L LQ
Sbjct: 189 DAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQ 248
Query: 229 HNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLV 288
HNQL SGL A L L L L N L VP LPR L L L N + + A L
Sbjct: 249 HNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLH 308
Query: 289 ATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRN 348
GL L L +N+L S+ + A R LR L +L L GN L R+P LP LR L L N
Sbjct: 309 GARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHN 368
Query: 349 QLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 391
+ L L L EL+LA+NRL + + L+AL+
Sbjct: 369 HVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALR 411
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 294 bits (752), Expect = 1e-79
Identities = 178/443 (40%), Positives = 232/443 (52%), Gaps = 89/443 (20%)
Query: 39 PLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLS-------------------- 78
P +CP C+C + VDC G+DLR FP ++ HLS
Sbjct: 111 PAAVSCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRL 170
Query: 79 ----LQNNQLQ---------------------------------------ELPYNELSRL 95
LQNN+L + N L+++
Sbjct: 171 ETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKI 230
Query: 96 SGL--------RTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHN--------------- 132
GL R++ LHNN ++ GLPD F + ++ L ++ N
Sbjct: 231 YGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYK 290
Query: 133 ---KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTT 189
KNN + K+P GA S + LRELYLQ+N LTD GLD TF KL SLEYLDLS N L+
Sbjct: 291 LHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSR 350
Query: 190 VPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLH 249
VPAGLPR+L +LHL +N IR V+A L R L YLLL NQL G+ A + L+ LH
Sbjct: 351 VPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLH 410
Query: 250 TLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVH 309
T+HLY N L+RVP LPRR+R L++ HN + +G D T L ELNL+YNR+ S +VH
Sbjct: 411 TVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVH 470
Query: 310 HRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSL 369
AFR+LR LRSLDL+GN+L LP GLP + L+++RN+L L L G+ QLREL L
Sbjct: 471 RDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYL 530
Query: 370 AHNRLRVGDIGPGTWHELQALQV 392
NRLR +GP W +L LQ+
Sbjct: 531 TSNRLRSRALGPRAWVDLAHLQL 553
Score = 175 bits (443), Expect = 8e-44
Identities = 120/348 (34%), Positives = 169/348 (48%), Gaps = 18/348 (5%)
Query: 63 LRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLT 122
LR P ++ A L L+NN+L+++P S LS LR L L NN ++ EGL +E F L+
Sbjct: 277 LRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLS 336
Query: 123 QLQHLCVAHN------------------KNNLISKVPRGALSRQTQLRELYLQHNQLTDS 164
L++L ++ N + N I V L+ L L L NQL +
Sbjct: 337 SLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQ 396
Query: 165 GLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRY 224
G+ F L L + L +N L VP+GLPR + L + N+I + L
Sbjct: 397 GIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEE 456
Query: 225 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 284
L L +N++ S + A R LR L +L L GN L +PP LPR + L + N +AAL
Sbjct: 457 LNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALAR 516
Query: 285 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 344
LV L EL L NRL S + RA+ L L+ LD+AGNQLT +P GLP L L
Sbjct: 517 GALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLY 576
Query: 345 LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQV 392
LQ N++ + L+ + L N+L VG + + L+ LQV
Sbjct: 577 LQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 624
Score = 135 bits (339), Expect = 9e-32
Identities = 99/299 (33%), Positives = 144/299 (48%), Gaps = 30/299 (10%)
Query: 53 VDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEG 112
++ +D +L P + R+ L L+ N ++ + N L+ + L L LH+N + +G
Sbjct: 338 LEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQG 397
Query: 113 LPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLD--ATT 170
+ AF+ L +L H NN + +VP G R +R L + HNQ+T G + ATT
Sbjct: 398 IHPLAFQGLKRLH---TVHLYNNALERVPSGLPRR---VRTLMILHNQITGIGREDFATT 451
Query: 171 ----------------------FSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRI 208
F KL L LDLS N+L T+P GLPR + +L + RN +
Sbjct: 452 YFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNEL 511
Query: 209 RQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRR 268
+ L G LR L L N+L S L A L L L + GN L +P LP
Sbjct: 512 AALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPES 571
Query: 269 LRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGN 327
L L L +N ++A+ A +TP L + L +N+LA V AFRRL+ L+ LD+ GN
Sbjct: 572 LEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 121 bits (303), Expect = 1e-27
Identities = 113/413 (27%), Positives = 175/413 (42%), Gaps = 71/413 (17%)
Query: 43 ACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 102
ACP C+C TVDC G L+ P NI R + L L N + + N+ + L LR L
Sbjct: 33 ACPALCTCTGT-TVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQ 91
Query: 103 LHNNLISSEGLPDEAFESLTQLQHLCVAHNK---------------------NNLISKVP 141
L N I + + AF+ + +L+ L + N+ N I +P
Sbjct: 92 LMENQIGA--VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 142 RGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG----LPRT 197
R A T L+ L L NQ+ S ++ F L LE L L++N +TT+P +P+
Sbjct: 150 RKAFRGATDLKNLQLDKNQI--SCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPK- 206
Query: 198 LAILHLGRNR-------------IRQ-------VEAARLHGARGLRYLLLQHNQLGSSGL 237
L L N +RQ + + RGL +Q ++ SG
Sbjct: 207 LRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQ 266
Query: 238 PAGALRPLRGLHT-------------LHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 284
P L + + G GL +P LP + + L N + ++
Sbjct: 267 GEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPP 326
Query: 285 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 344
L ++L+ N++ A + AF+ LR+L SL L GN++T LP G+ GL TLQ
Sbjct: 327 GAFSPYRKLRRIDLSNNQI--AEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQ 384
Query: 345 ---LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRH 394
L N++ + P+ L L LSL N+++ + GT+ L+A+Q H
Sbjct: 385 LLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ--SLAKGTFTSLRAIQTLH 435
Score = 92.4 bits (228), Expect = 7e-19
Identities = 98/404 (24%), Positives = 170/404 (42%), Gaps = 61/404 (15%)
Query: 43 ACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 102
+CP C+C VDC G L P N+ + L+ N ++ +P S LR ++
Sbjct: 281 SCPAMCTCSN-GIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 339
Query: 103 LHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLT 162
L NN I+ + +AF+ L L L + NK I+ +PRG L+ L L N++
Sbjct: 340 LSNNQIAE--IAPDAFQGLRSLNSLVLYGNK---ITDLPRGVFGGLYTLQLLLLNANKIN 394
Query: 163 DSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL---PRTLAILHLGRN------------- 206
DA F L +L L L N++ ++ G R + LHL +N
Sbjct: 395 CIRPDA--FQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLAD 452
Query: 207 -----------------------RIRQVEAARLHGARGLRYLL--LQHNQLGSSGLPAGA 241
RI Q+++ + + +Y + + QL S +
Sbjct: 453 FLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNSE-CNSDV 511
Query: 242 LRPLR---GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVAT-PGLTELN 297
+ P + + + L ++P +P+ L L +N ++ L A + L ++N
Sbjct: 512 VCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKIN 571
Query: 298 LAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGL---PTGLRTLQLQRNQLRMLE 354
L+ N+++ + AF ++ L L NQL + G+ GLRTL L+ N++ +
Sbjct: 572 LSNNKVSE--IEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIH 629
Query: 355 PEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLVS 398
+ GL +R LSL N++ + PG + LQ+L + L +
Sbjct: 630 NDSFTGLRNVRLLSLYDNQITT--VSPGAFDTLQSLSTLNLLAN 671
Score = 66.2 bits (160), Expect = 5e-11
Identities = 93/365 (25%), Positives = 144/365 (39%), Gaps = 67/365 (18%)
Query: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNEL-SRLSGLRTLN 102
CP +C C + V+C L L P+ I ++ L L NN++ L + +L+ L+ +N
Sbjct: 513 CPHKCRC-EANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKIN 571
Query: 103 LHNNLISSEGLPDEAFESLTQLQHLCVAHN---------------------KNNLISKVP 141
L NN +S + D AFE + L + N +NN IS +
Sbjct: 572 LSNNKVSE--IEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIH 629
Query: 142 RGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHN------QLTTVPAGLP 195
+ + +R L L NQ+T A F L SL L+L N QL + L
Sbjct: 630 NDSFTGLRNVRLLSLYDNQITTVSPGA--FDTLQSLSTLNLLANPFNCNCQLAWLGGWLR 687
Query: 196 RTLAILHLGRNRIRQVEAARLHGARGLRY--LLLQHNQLGSSGLPAGA------------ 241
+ + G R + + R + + + + Q LP
Sbjct: 688 KRKIVT--GNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLPRPQCPQECACLDTVV 745
Query: 242 ------LRPL-----RGLHTLHLYGNGLDRVPPALP--RRLRALVLPHNHVAALGARDLV 288
LR L + + L+L GN VP L + L+ + L +N +++L
Sbjct: 746 RCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFT 805
Query: 289 ATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGL---PTGLRTLQL 345
LT L L+YN L + AF+ LR+LR L L GN ++ L G+ T L L +
Sbjct: 806 NMSQLTTLILSYNALQC--IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 863
Query: 346 QRNQL 350
N L
Sbjct: 864 GANPL 868
Score = 58.5 bits (140), Expect = 1e-08
Identities = 56/170 (32%), Positives = 80/170 (47%), Gaps = 17/170 (10%)
Query: 25 LEDAAFPHLG-----ESLQPLPRA-CPLRCSCPRVDTV-DCDGLDLRVFPDNITRAAQHL 77
L+D AFP E LPR CP C+C +DTV C LR P I + L
Sbjct: 709 LQDVAFPDFRCEEGQEEGGCLPRPQCPQECAC--LDTVVRCSNKHLRALPKGIPKNVTEL 766
Query: 78 SLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLI 137
L NQ +P +LS L+ ++L NN ISS L + +F +++QL L +++ N +
Sbjct: 767 YLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISS--LSNSSFTNMSQLTTLILSY---NAL 820
Query: 138 SKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQL 187
+P A LR L L N + S L F+ + SL +L + N L
Sbjct: 821 QCIPPLAFQGLRSLRLLSLHGNDI--STLQEGIFADVTSLSHLAIGANPL 868
>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
Length = 811
Score = 118 bits (295), Expect = 1e-26
Identities = 118/357 (33%), Positives = 158/357 (44%), Gaps = 43/357 (12%)
Query: 36 SLQPLPR-ACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQH----LSLQNNQLQELPYN 90
+L PL CP RC C + C LRV P + + H SL N + +
Sbjct: 18 ALPPLAEPVCPERCDCQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAF 77
Query: 91 ELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQ 150
+ RL LR L+L N I S L + FE L++L+ L + NNL+ + G L+ +
Sbjct: 78 DFHRLGQLRRLDLQYNQIRS--LHPKTFEKLSRLEELYLG---NNLLQALAPGTLAPLRK 132
Query: 151 LRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLA---ILHLGRNR 207
LR LY N++ S L +F L SL L L N L +P + L LHL NR
Sbjct: 133 LRILYANGNEI--SRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNR 190
Query: 208 IRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPR 267
IR + LR+L L N+L S A PLR L +L L N L + P + +
Sbjct: 191 IRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQ 250
Query: 268 RLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGN 327
L P L L+L N+L + AF L ALR L L GN
Sbjct: 251 HL---------------------PRLGLLSLRGNQLT--HLAPEAFWGLEALRELRLEGN 287
Query: 328 QLTRLPMGLPTGLRTLQ---LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV--GDI 379
+L++LP L L +L+ L N+L L P L +LRELSL +N L GDI
Sbjct: 288 RLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDI 344
Score = 38.5 bits (88), Expect = 0.012
Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 340 LRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQV 392
LR L LQ NQ+R L P+ L +L EL L +N L+ + PGT L+ L++
Sbjct: 85 LRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQA--LAPGTLAPLRKLRI 135
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 117 bits (293), Expect = 2e-26
Identities = 106/357 (29%), Positives = 156/357 (43%), Gaps = 22/357 (6%)
Query: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103
CP C+C R V+C G + P + A L + N + EL + +S L L +
Sbjct: 31 CPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRI 90
Query: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTD 163
N +S + AF +L L++L +A+NK + +P G L L L NQL
Sbjct: 91 EKNELSR--ITPGAFRNLGSLRYLSLANNK---LQVLPIGLFQGLDSLESLLLSSNQLLQ 145
Query: 164 SGLDATTFSKLHSLEYLDLSHNQLTTVPAGL---PRTLAILHLGRNRIRQVEAARLHGAR 220
+ FS+ +L+ L L N L +P G L L+LG+N + +
Sbjct: 146 --IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLG 203
Query: 221 GLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPAL---PRRLRALVLPHN 277
L+ L L N+L + +P G L L L L N + + P L L+ L L +N
Sbjct: 204 NLQVLRLYENRL--TDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNN 261
Query: 278 HVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLP 337
H++ L + P L L L N L + F + LR L L N ++ LP +
Sbjct: 262 HISQLPPSIFMQLPQLNRLTLFGNSLKELSL--GIFGPMPNLRELWLYDNHISSLPDNVF 319
Query: 338 TGLRTLQ---LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 391
+ LR LQ L RNQ+ + P GL +LRELSL N L+ D+ + L LQ
Sbjct: 320 SNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQ--DLDGNVFRMLANLQ 374
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 75 QHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHN 132
Q++SLQNN+L++LP N + ++GL + L NN + E LP F+ L +L L + N
Sbjct: 374 QNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQL--ENLPLGIFDHLGKLCELRLYDN 429
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 117 bits (293), Expect = 2e-26
Identities = 106/357 (29%), Positives = 156/357 (43%), Gaps = 22/357 (6%)
Query: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103
CP C+C R V+C G + P + A L + N + EL + +S L L +
Sbjct: 25 CPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRI 84
Query: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTD 163
N +S + AF +L L++L +A+NK + +P G L L L NQL
Sbjct: 85 EKNELSR--ITPGAFRNLGSLRYLSLANNK---LQVLPIGLFQGLDSLESLLLSSNQLLQ 139
Query: 164 SGLDATTFSKLHSLEYLDLSHNQLTTVPAGL---PRTLAILHLGRNRIRQVEAARLHGAR 220
+ FS+ +L+ L L N L +P G L L+LG+N + +
Sbjct: 140 --IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLG 197
Query: 221 GLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPAL---PRRLRALVLPHN 277
L+ L L N+L + +P G L L L L N + + P L L+ L L +N
Sbjct: 198 NLQVLRLYENRL--TDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNN 255
Query: 278 HVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLP 337
H++ L + P L L L N L + F + LR L L N ++ LP +
Sbjct: 256 HISQLPPSIFMQLPQLNRLTLFGNSLKELSL--GIFGPMPNLRELWLYDNHISSLPDNVF 313
Query: 338 TGLRTLQ---LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 391
+ LR LQ L RNQ+ + P GL +LRELSL N L+ D+ + L LQ
Sbjct: 314 SNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQ--DLDGNVFRMLANLQ 368
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 75 QHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHN 132
Q++SLQNN+L++LP N + ++GL + L NN + E LP F+ L +L L + N
Sbjct: 368 QNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQL--ENLPLGIFDHLGKLCELRLYDN 423
>gi|71040111 fibromodulin precursor [Homo sapiens]
Length = 376
Score = 117 bits (292), Expect = 3e-26
Identities = 86/276 (31%), Positives = 126/276 (45%), Gaps = 26/276 (9%)
Query: 24 GLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQHLSLQN 81
G+++ G P PR CP C CP + CD +L+ P +R +++ QN
Sbjct: 56 GVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRM-KYVYFQN 114
Query: 82 NQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNK-------- 133
NQ+ + +GL + LH N I+S+ + + F L L+ L + HN
Sbjct: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
Query: 134 ----------NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLS 183
+N IS+VP AL L LYLQHN++ + G ++ L SL LDLS
Sbjct: 175 PRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLS 231
Query: 184 HNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALR 243
+N L VP GLP L L++ N + V + GA L Y+ L HN L ++GL +
Sbjct: 232 YNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFN 291
Query: 244 PLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHV 279
L L L N L ++PP + L L L N +
Sbjct: 292 S-SSLLELDLSYNQLQKIPP-VNTNLENLYLQGNRI 325
Score = 115 bits (289), Expect = 6e-26
Identities = 79/218 (36%), Positives = 109/218 (50%), Gaps = 5/218 (2%)
Query: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
+NN I+ + G T L + L NQ+T + FSKL LE L L HN LT +P
Sbjct: 113 QNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPG 172
Query: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
LPR+L LHL N+I +V L G L L LQHN++ G ++R LR L L
Sbjct: 173 PLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLD 229
Query: 253 LYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRA 312
L N L +VP LP L L + HN+V + P L + L++N L + +
Sbjct: 230 LSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNT 289
Query: 313 FRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL 350
F +L LDL+ NQL ++P + T L L LQ N++
Sbjct: 290 FNS-SSLLELDLSYNQLQKIP-PVNTNLENLYLQGNRI 325
Score = 89.4 bits (220), Expect = 6e-18
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Query: 194 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 253
+P + ++ N+I ++ A GL ++ L NQ+ S + LR L L+L
Sbjct: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
Query: 254 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 313
N L R+P LPR LR L L HN ++ + L LT L L +N + +
Sbjct: 163 DHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEV---GSSM 219
Query: 314 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 373
R LR+L LDL+ N L ++P GLP+ L L ++ N + + G +L + L+HN
Sbjct: 220 RGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNS 279
Query: 374 LRVGDIGPGTWHELQALQV 392
L + T++ L++
Sbjct: 280 LTNNGLASNTFNSSSLLEL 298
Score = 63.9 bits (154), Expect = 3e-10
Identities = 37/113 (32%), Positives = 57/113 (50%)
Query: 263 PALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSL 322
P +P R++ + +N + ++ GL + L N++ S +V + F +LR L L
Sbjct: 101 PFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERL 160
Query: 323 DLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLR 375
L N LTR+P LP LR L L NQ+ + L GL+ L L L HN ++
Sbjct: 161 YLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQ 213
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 113 bits (282), Expect = 4e-25
Identities = 98/367 (26%), Positives = 161/367 (43%), Gaps = 32/367 (8%)
Query: 40 LPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLR 99
LP C L T+ C L P L L N + +P + L L
Sbjct: 316 LPSGCSLSYR-----TISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLE 370
Query: 100 TLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVP 141
L+L N I+S G+ +AF+ L +L L + N N + +
Sbjct: 371 RLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAID 430
Query: 142 RGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAIL 201
+LS QL L L+ N L+++ ++ F L SL YL L N+ +P GLP ++ L
Sbjct: 431 EESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEEL 490
Query: 202 HLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRV 261
+L N+I ++ + R + ++L++N++ + + A L ++ L N L V
Sbjct: 491 YLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHV 550
Query: 262 PPALPRRLRALVLPHNHVAAL-GARDLVATPGLTELNLAYNRLASARVHHRAFR-RLRAL 319
P LP+ L LVL N + + G PGL L L++N+LA + +F +L
Sbjct: 551 PSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSL 610
Query: 320 RSLDLAGNQLTRLPMGLPT--GLRTLQLQRNQLRMLEPEPLAGLDQ-----LRELSLAHN 372
R L L N L +P G+ L L+L N++R + PE + ++ L L L +N
Sbjct: 611 RELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENN 670
Query: 373 RLRVGDI 379
+++ +I
Sbjct: 671 YIKIREI 677
Score = 94.4 bits (233), Expect = 2e-19
Identities = 75/267 (28%), Positives = 118/267 (44%), Gaps = 9/267 (3%)
Query: 135 NLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL 194
N I+ +P A + L L L N +T SG+ F L L L++ N L +P+ L
Sbjct: 353 NSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQL 412
Query: 195 PRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLY 254
P TL L + N ++ ++ L L L L+ N L + + A +PL+ L L L
Sbjct: 413 PSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLG 472
Query: 255 GNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFR 314
N +P LP + L L +N + + T + + L YN++ R+ A+
Sbjct: 473 KNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWI 532
Query: 315 RLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQ-LRELSLAHNR 373
L S+DL+ N+L +P LP L L L NQ+ + ++ L L L+ N+
Sbjct: 533 NQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNK 592
Query: 374 LRVGDIGP------GTWHELQALQVRH 394
L D G G +H L+ L + H
Sbjct: 593 L--ADDGMDRVSFYGAYHSLRELFLDH 617
Score = 88.2 bits (217), Expect = 1e-17
Identities = 65/237 (27%), Positives = 106/237 (44%), Gaps = 5/237 (2%)
Query: 176 SLEYLDLS--HNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLG 233
SL Y +S + LT +P + L L N I + +G L L L N +
Sbjct: 321 SLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNIT 380
Query: 234 SSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGL 293
SSG+ A + L+ L L++ GN L ++P LP L L + N++ A+ L L
Sbjct: 381 SSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQL 440
Query: 294 TELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRML 353
L L N L+ A V+ AF+ L++L L L N+ +P GLP + L L+ NQ+ +
Sbjct: 441 VTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEI 500
Query: 354 EPEPLAGLDQLRELSLAHNRLRVGDIGPGTW---HELQALQVRHRLVSHTVPRAPPS 407
++ + L +N++ I P W L+++ + + + H P S
Sbjct: 501 TEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKS 557
Score = 82.8 bits (203), Expect = 5e-16
Identities = 76/299 (25%), Positives = 129/299 (43%), Gaps = 33/299 (11%)
Query: 56 VDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPD 115
++ DG +L P + + L + N LQ + LS L+ L TL L N +S +
Sbjct: 398 LNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNP 457
Query: 116 EAFESLTQLQHLCVAHNK------------------NNLISKVPRGALSRQTQLRELYLQ 157
AF+ L L +L + NK NN I ++ + ++ + L+
Sbjct: 458 LAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLR 517
Query: 158 HNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARL- 216
+N++ ++ + + +LE +DLS+N+L VP+ LP++L L L N+I ++
Sbjct: 518 YNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFG 577
Query: 217 HGARGLRYLLLQHNQLGSSGLPA----GALRPLRGLHTLHLYGNGLDRVPPALP--RRLR 270
H GL YL L N+L G+ GA LR L H N L +PP + + L
Sbjct: 578 HMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDH---NDLKSIPPGIQEMKALH 634
Query: 271 ALVLPHNHVAALGARDLVAT-----PGLTELNLAYNRLASARVHHRAFRRLRALRSLDL 324
L L +N + + ++ L L+L N + + F +R+ S+ L
Sbjct: 635 FLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIKIREIPSYTFSCIRSYSSIVL 693
>gi|4502403 biglycan preproprotein [Homo sapiens]
Length = 368
Score = 111 bits (277), Expect = 1e-24
Identities = 88/263 (33%), Positives = 122/263 (46%), Gaps = 26/263 (9%)
Query: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103
CP C C + V C L L+ P I+ L LQNN + EL ++ L L L L
Sbjct: 63 CPFGCHC-HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVL 121
Query: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHN------------------KNNLISKVPRGAL 145
NN IS + ++AF L +LQ L ++ N +N I KVP+G
Sbjct: 122 VNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVF 179
Query: 146 SRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGR 205
S + + + N L +SG + F L L YL +S +LT +P LP TL LHL
Sbjct: 180 SGLRNMNCIEMGGNPLENSGFEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDH 238
Query: 206 NRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPAL 265
N+I+ +E L L L L HNQ+ + G+L L L LHL N L RVP L
Sbjct: 239 NKIQAIELEDLLRYSKLYRLGLGHNQIRM--IENGSLSFLPTLRELHLDNNKLARVPSGL 296
Query: 266 P--RRLRALVLPHNHVAALGARD 286
P + L+ + L N++ +G D
Sbjct: 297 PDLKLLQVVYLHSNNITKVGVND 319
Score = 55.5 bits (132), Expect = 9e-08
Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Query: 257 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 316
GL VP + L L +N ++ L D L L L N+++ ++H +AF L
Sbjct: 80 GLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKIS--KIHEKAFSPL 137
Query: 317 RALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV 376
R L+ L ++ N L +P LP+ L L++ N++R + +GL + + + N L
Sbjct: 138 RKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLEN 197
Query: 377 GDIGPGTWHELQALQVR 393
PG + L+ +R
Sbjct: 198 SGFEPGAFDGLKLNYLR 214
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 110 bits (276), Expect = 2e-24
Identities = 83/278 (29%), Positives = 129/278 (46%), Gaps = 26/278 (9%)
Query: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103
CP RC C + V C L L P ++ L LQNN++ E+ + L L L L
Sbjct: 54 CPFRCQC-HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALIL 112
Query: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRGAL 145
NN IS + AF L +L+ L ++ N+ N I+KV +
Sbjct: 113 VNNKISK--VSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTF 170
Query: 146 SRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGR 205
+ Q+ + L N L SG++ F + L Y+ ++ +T++P GLP +L LHL
Sbjct: 171 NGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDG 230
Query: 206 NRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPAL 265
N+I +V+AA L G L L L N + S + G+L L LHL N L RVP L
Sbjct: 231 NKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGL 288
Query: 266 P--RRLRALVLPHNHVAALGARDLVATPGLTELNLAYN 301
+ ++ + L +N+++ +G+ D PG +Y+
Sbjct: 289 AEHKYIQVVYLHNNNISVVGSSDF-CPPGHNTKKASYS 325
Score = 84.3 bits (207), Expect = 2e-16
Identities = 56/204 (27%), Positives = 95/204 (46%), Gaps = 2/204 (0%)
Query: 177 LEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSG 236
L + S L VP LP +L L N+I +++ + L L+L +N++ S
Sbjct: 62 LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKI--SK 119
Query: 237 LPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTEL 296
+ GA PL L L+L N L +P +P+ L+ L N + + + +
Sbjct: 120 VSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVI 179
Query: 297 NLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPE 356
L N L S+ + + AF+ ++ L + +A +T +P GLP L L L N++ ++
Sbjct: 180 ELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAA 239
Query: 357 PLAGLDQLRELSLAHNRLRVGDIG 380
L GL+ L +L L+ N + D G
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNG 263
Score = 53.9 bits (128), Expect = 3e-07
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 2/134 (1%)
Query: 257 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 316
GLD+VP LP L L +N + + D L L L N+++ +V AF L
Sbjct: 71 GLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKIS--KVSPGAFTPL 128
Query: 317 RALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV 376
L L L+ NQL LP +P L+ L+ N++ + GL+Q+ + L N L+
Sbjct: 129 VKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS 188
Query: 377 GDIGPGTWHELQAL 390
I G + ++ L
Sbjct: 189 SGIENGAFQGMKKL 202
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 110 bits (276), Expect = 2e-24
Identities = 83/278 (29%), Positives = 129/278 (46%), Gaps = 26/278 (9%)
Query: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103
CP RC C + V C L L P ++ L LQNN++ E+ + L L L L
Sbjct: 54 CPFRCQC-HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALIL 112
Query: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRGAL 145
NN IS + AF L +L+ L ++ N+ N I+KV +
Sbjct: 113 VNNKISK--VSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTF 170
Query: 146 SRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGR 205
+ Q+ + L N L SG++ F + L Y+ ++ +T++P GLP +L LHL
Sbjct: 171 NGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDG 230
Query: 206 NRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPAL 265
N+I +V+AA L G L L L N + S + G+L L LHL N L RVP L
Sbjct: 231 NKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGL 288
Query: 266 P--RRLRALVLPHNHVAALGARDLVATPGLTELNLAYN 301
+ ++ + L +N+++ +G+ D PG +Y+
Sbjct: 289 AEHKYIQVVYLHNNNISVVGSSDF-CPPGHNTKKASYS 325
Score = 84.3 bits (207), Expect = 2e-16
Identities = 56/204 (27%), Positives = 95/204 (46%), Gaps = 2/204 (0%)
Query: 177 LEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSG 236
L + S L VP LP +L L N+I +++ + L L+L +N++ S
Sbjct: 62 LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKI--SK 119
Query: 237 LPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTEL 296
+ GA PL L L+L N L +P +P+ L+ L N + + + +
Sbjct: 120 VSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVI 179
Query: 297 NLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPE 356
L N L S+ + + AF+ ++ L + +A +T +P GLP L L L N++ ++
Sbjct: 180 ELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAA 239
Query: 357 PLAGLDQLRELSLAHNRLRVGDIG 380
L GL+ L +L L+ N + D G
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNG 263
Score = 53.9 bits (128), Expect = 3e-07
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 2/134 (1%)
Query: 257 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 316
GLD+VP LP L L +N + + D L L L N+++ +V AF L
Sbjct: 71 GLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKIS--KVSPGAFTPL 128
Query: 317 RALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV 376
L L L+ NQL LP +P L+ L+ N++ + GL+Q+ + L N L+
Sbjct: 129 VKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKS 188
Query: 377 GDIGPGTWHELQAL 390
I G + ++ L
Sbjct: 189 SGIENGAFQGMKKL 202
>gi|225579152 insulin-like growth factor binding protein, acid
labile subunit isoform 1 precursor [Homo sapiens]
Length = 643
Score = 110 bits (274), Expect = 3e-24
Identities = 113/327 (34%), Positives = 147/327 (44%), Gaps = 29/327 (8%)
Query: 63 LRVFPDNITR---AAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFE 119
L V PD R + + L L N+L L S L+ LR L+L N + + + F
Sbjct: 220 LAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA--IKANVFV 277
Query: 120 SLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEY 179
L +LQ L + NLI+ V GA LR L L HN++ +GL TF L L
Sbjct: 278 QLPRLQKLYL---DRNLIAAVAPGAFLGLKALRWLDLSHNRV--AGLLEDTFPGLLGLRV 332
Query: 180 LDLSHNQLTTVPAGLPRTLAILH------LGRNRIRQVEAARLHGARGLRYLLLQHNQLG 233
L LSHN + ++ PRT LH LG NRIRQ+ G L L L HNQL
Sbjct: 333 LRLSHNAIASLR---PRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQ 389
Query: 234 SSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA---RDLVAT 290
+ AGA L + ++L GN L +P + R L L H + LG
Sbjct: 390 E--VKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL 447
Query: 291 PGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ---LQR 347
GL L L N L + ++ L L LDL NQLT LP L GL L+ L R
Sbjct: 448 SGLRRLFLKDNGLVG--IEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSR 505
Query: 348 NQLRMLEPEPLAGLDQLRELSLAHNRL 374
N+L L + L L + L ++HNRL
Sbjct: 506 NRLAELPADALGPLQRAFWLDVSHNRL 532
Score = 108 bits (271), Expect = 7e-24
Identities = 120/380 (31%), Positives = 160/380 (42%), Gaps = 31/380 (8%)
Query: 10 LLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVD-----CDGLDLR 64
LLL + GP + G D P GE+ P ACP C C D D C +L
Sbjct: 51 LLLSWVALGPRSLEGA-DPGTP--GEAEGP---ACPAACVCSYDDDADELSVFCSSRNLT 104
Query: 65 VFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQL 124
PD + Q L L N L +P LS L LNL + S L +A L L
Sbjct: 105 RLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGS--LEPQA---LLGL 159
Query: 125 QHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSH 184
++LC H + N + + G + L L L +N+L S L+ F L SL L+L
Sbjct: 160 ENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRL--SRLEDGLFEGLGSLWDLNLGW 217
Query: 185 NQLTTVPAGLPRTLAILH---LGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGA 241
N L +P R L L L NR+ ++ A G LR L L N L + A
Sbjct: 218 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNAL--RAIKANV 275
Query: 242 LRPLRGLHTLHLYGNGLDRVPPAL---PRRLRALVLPHNHVAALGARDLVATPGLTELNL 298
L L L+L N + V P + LR L L HN VA L GL L L
Sbjct: 276 FVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRL 335
Query: 299 AYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTG---LRTLQLQRNQLRMLEP 355
++N +AS R R F+ L L L L N++ +L G L L L NQL+ ++
Sbjct: 336 SHNAIASLR--PRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKA 393
Query: 356 EPLAGLDQLRELSLAHNRLR 375
GL + ++L+ N LR
Sbjct: 394 GAFLGLTNVAVMNLSGNCLR 413
Score = 102 bits (255), Expect = 5e-22
Identities = 109/332 (32%), Positives = 144/332 (43%), Gaps = 44/332 (13%)
Query: 76 HLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNN 135
HL L+ NQL+ L + L +L L NN +S L D FE L L L + N
Sbjct: 164 HLHLERNQLRSLALGTFAHTPALASLGLSNNRLSR--LEDGLFEGLGSLWDLNLGWNS-- 219
Query: 136 LISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG-- 193
++ +P A LREL L N+L + L FS L L LDLS N L + A
Sbjct: 220 -LAVLPDAAFRGLGSLRELVLAGNRL--AYLQPALFSGLAELRELDLSRNALRAIKANVF 276
Query: 194 --LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTL 251
LPR L L+L RN I V G + LR+L L HN++ +GL L GL L
Sbjct: 277 VQLPR-LQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRV--AGLLEDTFPGLLGLRVL 333
Query: 252 HLYGNGLDRVPPALPRRLR---ALVLPHNHVAALGARDLVATPGLTELNLAYNRLASAR- 307
L N + + P + L L L HN + L R L L L +N+L +
Sbjct: 334 RLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKA 393
Query: 308 ---------------------VHHRAFRRLRALRSLDLAGNQLTRLP----MGLPTGLRT 342
+ + FR L L SL L G+ L R+ GL +GLR
Sbjct: 394 GAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL-SGLRR 452
Query: 343 LQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 374
L L+ N L +E + L GL +L EL L N+L
Sbjct: 453 LFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 484
Score = 35.8 bits (81), Expect = 0.075
Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 26/94 (27%)
Query: 321 SLDLAGNQLTRLPMGLPTG------------------------LRTLQLQRNQLRMLEPE 356
S+ + LTRLP G+P G L L LQ QL LEP+
Sbjct: 95 SVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQ 154
Query: 357 PLAGLDQLRELSLAHNRLRVGDIGPGTWHELQAL 390
L GL+ L L L N+LR + GT+ AL
Sbjct: 155 ALLGLENLCHLHLERNQLR--SLALGTFAHTPAL 186
>gi|4826772 insulin-like growth factor binding protein, acid labile
subunit isoform 2 precursor [Homo sapiens]
Length = 605
Score = 110 bits (274), Expect = 3e-24
Identities = 113/327 (34%), Positives = 147/327 (44%), Gaps = 29/327 (8%)
Query: 63 LRVFPDNITR---AAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFE 119
L V PD R + + L L N+L L S L+ LR L+L N + + + F
Sbjct: 182 LAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA--IKANVFV 239
Query: 120 SLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEY 179
L +LQ L + NLI+ V GA LR L L HN++ +GL TF L L
Sbjct: 240 QLPRLQKLYL---DRNLIAAVAPGAFLGLKALRWLDLSHNRV--AGLLEDTFPGLLGLRV 294
Query: 180 LDLSHNQLTTVPAGLPRTLAILH------LGRNRIRQVEAARLHGARGLRYLLLQHNQLG 233
L LSHN + ++ PRT LH LG NRIRQ+ G L L L HNQL
Sbjct: 295 LRLSHNAIASLR---PRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQ 351
Query: 234 SSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA---RDLVAT 290
+ AGA L + ++L GN L +P + R L L H + LG
Sbjct: 352 E--VKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL 409
Query: 291 PGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ---LQR 347
GL L L N L + ++ L L LDL NQLT LP L GL L+ L R
Sbjct: 410 SGLRRLFLKDNGLVG--IEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSR 467
Query: 348 NQLRMLEPEPLAGLDQLRELSLAHNRL 374
N+L L + L L + L ++HNRL
Sbjct: 468 NRLAELPADALGPLQRAFWLDVSHNRL 494
Score = 108 bits (271), Expect = 7e-24
Identities = 120/380 (31%), Positives = 160/380 (42%), Gaps = 31/380 (8%)
Query: 10 LLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVD-----CDGLDLR 64
LLL + GP + G D P GE+ P ACP C C D D C +L
Sbjct: 13 LLLSWVALGPRSLEGA-DPGTP--GEAEGP---ACPAACVCSYDDDADELSVFCSSRNLT 66
Query: 65 VFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQL 124
PD + Q L L N L +P LS L LNL + S L +A L L
Sbjct: 67 RLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGS--LEPQA---LLGL 121
Query: 125 QHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSH 184
++LC H + N + + G + L L L +N+L S L+ F L SL L+L
Sbjct: 122 ENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRL--SRLEDGLFEGLGSLWDLNLGW 179
Query: 185 NQLTTVPAGLPRTLAILH---LGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGA 241
N L +P R L L L NR+ ++ A G LR L L N L + A
Sbjct: 180 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNAL--RAIKANV 237
Query: 242 LRPLRGLHTLHLYGNGLDRVPPAL---PRRLRALVLPHNHVAALGARDLVATPGLTELNL 298
L L L+L N + V P + LR L L HN VA L GL L L
Sbjct: 238 FVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRL 297
Query: 299 AYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTG---LRTLQLQRNQLRMLEP 355
++N +AS R R F+ L L L L N++ +L G L L L NQL+ ++
Sbjct: 298 SHNAIASLR--PRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKA 355
Query: 356 EPLAGLDQLRELSLAHNRLR 375
GL + ++L+ N LR
Sbjct: 356 GAFLGLTNVAVMNLSGNCLR 375
Score = 102 bits (255), Expect = 5e-22
Identities = 109/332 (32%), Positives = 144/332 (43%), Gaps = 44/332 (13%)
Query: 76 HLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNN 135
HL L+ NQL+ L + L +L L NN +S L D FE L L L + N
Sbjct: 126 HLHLERNQLRSLALGTFAHTPALASLGLSNNRLSR--LEDGLFEGLGSLWDLNLGWNS-- 181
Query: 136 LISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG-- 193
++ +P A LREL L N+L + L FS L L LDLS N L + A
Sbjct: 182 -LAVLPDAAFRGLGSLRELVLAGNRL--AYLQPALFSGLAELRELDLSRNALRAIKANVF 238
Query: 194 --LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTL 251
LPR L L+L RN I V G + LR+L L HN++ +GL L GL L
Sbjct: 239 VQLPR-LQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRV--AGLLEDTFPGLLGLRVL 295
Query: 252 HLYGNGLDRVPPALPRRLR---ALVLPHNHVAALGARDLVATPGLTELNLAYNRLASAR- 307
L N + + P + L L L HN + L R L L L +N+L +
Sbjct: 296 RLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKA 355
Query: 308 ---------------------VHHRAFRRLRALRSLDLAGNQLTRLP----MGLPTGLRT 342
+ + FR L L SL L G+ L R+ GL +GLR
Sbjct: 356 GAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL-SGLRR 414
Query: 343 LQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 374
L L+ N L +E + L GL +L EL L N+L
Sbjct: 415 LFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 446
Score = 35.8 bits (81), Expect = 0.075
Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 26/94 (27%)
Query: 321 SLDLAGNQLTRLPMGLPTG------------------------LRTLQLQRNQLRMLEPE 356
S+ + LTRLP G+P G L L LQ QL LEP+
Sbjct: 57 SVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQ 116
Query: 357 PLAGLDQLRELSLAHNRLRVGDIGPGTWHELQAL 390
L GL+ L L L N+LR + GT+ AL
Sbjct: 117 ALLGLENLCHLHLERNQLR--SLALGTFAHTPAL 148
>gi|41349454 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 110 bits (274), Expect = 3e-24
Identities = 103/345 (29%), Positives = 145/345 (42%), Gaps = 44/345 (12%)
Query: 19 PPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQH 76
PPP+ + FP CP C CP + CD +LR P I +
Sbjct: 59 PPPLPPGPPSIFPD-----------CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHY 106
Query: 77 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISS------EGLPDEAFESL--TQLQHLC 128
L LQNN + ELP +GLR +NL NN I E LP F + QL+ +
Sbjct: 107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVP 166
Query: 129 VAHNKN--------NLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 180
A +N N IS++P G S+ L L LQHN+L+D TF L +L L
Sbjct: 167 SALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQL 226
Query: 181 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 240
+L+HN L +P +P + L+L N+I + L ++ L +N+L GLP
Sbjct: 227 NLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKN 286
Query: 241 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 300
+ + L LHL N + V PA+ RL L L +N + + +
Sbjct: 287 SFN-ISNLLVLHLSHNRISSV-PAINNRLEHLYLNNNSIEKINGTQICP----------- 333
Query: 301 NRLASARVHHRAFRRLRALRSLDLAGNQL-TRLPMGLPTGLRTLQ 344
N L + + LR L L GN L +P+ L R LQ
Sbjct: 334 NDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQ 378
Score = 86.7 bits (213), Expect = 4e-17
Identities = 62/221 (28%), Positives = 101/221 (45%), Gaps = 4/221 (1%)
Query: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
+NN I+++P + T LR + L +N++ +D KL L +L + NQL VP+
Sbjct: 110 QNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEEVPS 167
Query: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
LPR L L L +N I ++ L L LQHN+L L+ L L+
Sbjct: 168 ALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLN 227
Query: 253 LYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRA 312
L N L ++PP +P + L L N + + + P L + L YN+L + +
Sbjct: 228 LAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNS 287
Query: 313 FRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRML 353
F + L L L+ N+++ +P + L L L N + +
Sbjct: 288 F-NISNLLVLHLSHNRISSVP-AINNRLEHLYLNNNSIEKI 326
Score = 79.0 bits (193), Expect = 8e-15
Identities = 60/214 (28%), Positives = 98/214 (45%), Gaps = 5/214 (2%)
Query: 187 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 246
L VP +P + L+L N I ++ A GLR++ L +N++ + L L
Sbjct: 94 LRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLP 150
Query: 247 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 306
GL L++ N L+ VP ALPR L L L NH++ + L L+L +NRL+
Sbjct: 151 GLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDG 210
Query: 307 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 366
F L+ L L+LA N L ++P +PT + L L N++ + L
Sbjct: 211 VFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAF 270
Query: 367 LSLAHNRLRVGDIGPGTWH--ELQALQVRHRLVS 398
+ L +N+L + +++ L L + H +S
Sbjct: 271 IRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRIS 304
>gi|4506041 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 110 bits (274), Expect = 3e-24
Identities = 103/345 (29%), Positives = 145/345 (42%), Gaps = 44/345 (12%)
Query: 19 PPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQH 76
PPP+ + FP CP C CP + CD +LR P I +
Sbjct: 59 PPPLPPGPPSIFPD-----------CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHY 106
Query: 77 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISS------EGLPDEAFESL--TQLQHLC 128
L LQNN + ELP +GLR +NL NN I E LP F + QL+ +
Sbjct: 107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVP 166
Query: 129 VAHNKN--------NLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 180
A +N N IS++P G S+ L L LQHN+L+D TF L +L L
Sbjct: 167 SALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQL 226
Query: 181 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 240
+L+HN L +P +P + L+L N+I + L ++ L +N+L GLP
Sbjct: 227 NLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKN 286
Query: 241 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 300
+ + L LHL N + V PA+ RL L L +N + + +
Sbjct: 287 SFN-ISNLLVLHLSHNRISSV-PAINNRLEHLYLNNNSIEKINGTQICP----------- 333
Query: 301 NRLASARVHHRAFRRLRALRSLDLAGNQL-TRLPMGLPTGLRTLQ 344
N L + + LR L L GN L +P+ L R LQ
Sbjct: 334 NDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQ 378
Score = 86.7 bits (213), Expect = 4e-17
Identities = 62/221 (28%), Positives = 101/221 (45%), Gaps = 4/221 (1%)
Query: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
+NN I+++P + T LR + L +N++ +D KL L +L + NQL VP+
Sbjct: 110 QNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEEVPS 167
Query: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
LPR L L L +N I ++ L L LQHN+L L+ L L+
Sbjct: 168 ALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLN 227
Query: 253 LYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRA 312
L N L ++PP +P + L L N + + + P L + L YN+L + +
Sbjct: 228 LAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNS 287
Query: 313 FRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRML 353
F + L L L+ N+++ +P + L L L N + +
Sbjct: 288 F-NISNLLVLHLSHNRISSVP-AINNRLEHLYLNNNSIEKI 326
Score = 79.0 bits (193), Expect = 8e-15
Identities = 60/214 (28%), Positives = 98/214 (45%), Gaps = 5/214 (2%)
Query: 187 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 246
L VP +P + L+L N I ++ A GLR++ L +N++ + L L
Sbjct: 94 LRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLP 150
Query: 247 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 306
GL L++ N L+ VP ALPR L L L NH++ + L L+L +NRL+
Sbjct: 151 GLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDG 210
Query: 307 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 366
F L+ L L+LA N L ++P +PT + L L N++ + L
Sbjct: 211 VFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAF 270
Query: 367 LSLAHNRLRVGDIGPGTWH--ELQALQVRHRLVS 398
+ L +N+L + +++ L L + H +S
Sbjct: 271 IRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRIS 304
>gi|4505047 lumican precursor [Homo sapiens]
Length = 338
Score = 107 bits (268), Expect = 2e-23
Identities = 74/239 (30%), Positives = 114/239 (47%), Gaps = 25/239 (10%)
Query: 44 CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101
C C+CP + CD L L+ P + ++L L+NNQ+ + ++ L+ L
Sbjct: 37 CAPECNCPESYPSAMYCDELKLKSVP-MVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
Query: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRG 143
L +NL+ + + F L QL+ L + HN +N I+K+ G
Sbjct: 96 ILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--G 153
Query: 144 ALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHL 203
+ L ++LQHN+L + + A F L SLEYLDLS NQ+ +P+GLP +L L+L
Sbjct: 154 SFEGLVNLTFIHLQHNRLKEDAVSAA-FKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
Query: 204 GRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVP 262
N+I + L+YL L HN+L SG+P + + L L L N L +P
Sbjct: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN-VSSLVELDLSYNKLKNIP 270
Score = 97.8 bits (242), Expect = 2e-20
Identities = 68/205 (33%), Positives = 104/205 (50%), Gaps = 5/205 (2%)
Query: 186 QLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPL 245
+L +VP +P + L+L N+I ++ L++L+L HN L +S + L
Sbjct: 57 KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
Query: 246 RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS 305
+ L LH+ N L LP+ L L L HN + LG+ + + LT ++L +NRL
Sbjct: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVN--LTFIHLQHNRLKE 173
Query: 306 ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLR 365
V AF+ L++L LDL+ NQ+ RLP GLP L TL L N++ + E + L+
Sbjct: 174 DAVS-AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQ 232
Query: 366 ELSLAHNRLRVGDIGPGTWHELQAL 390
L L+HN L I PG + +L
Sbjct: 233 YLRLSHNELADSGI-PGNSFNVSSL 256
Score = 31.6 bits (70), Expect = 1.4
Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 328 QLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTW--- 384
+L +PM +P G++ L L+ NQ+ ++ + + L+ L L HN L I +
Sbjct: 57 KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
Query: 385 HELQALQVRHRLVSHTVPRAPPS 407
+L+ L + H ++ +V P S
Sbjct: 116 KQLKKLHINHNNLTESVGPLPKS 138
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 107 bits (268), Expect = 2e-23
Identities = 117/372 (31%), Positives = 162/372 (43%), Gaps = 46/372 (12%)
Query: 38 QPLPRACPLRCSCPRVDTVDCDGLDL-RVFPDNITRAAQHLSLQNNQLQELPYNELSRLS 96
QP P CP C C D C G D+ R+ + H+ L L S ++
Sbjct: 17 QPFP--CPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQSQSFSGMT 74
Query: 97 GLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYL 156
L+ L + ++ IS+ + F L +L+ L ++ NK I+ +P L + L +L+L
Sbjct: 75 VLQRLMISDSHISA--VAPGTFSDLIKLKTLRLSRNK---ITHLPGALLDKMVLLEQLFL 129
Query: 157 QHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL---PRTLAILHLGRNRIRQVEA 213
HN L G+D F KL +L+ L L+ NQL +PA L L +L L N + +
Sbjct: 130 DHNAL--RGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPK 187
Query: 214 ARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPA----LPRRL 269
L L LLL N+L S L +G L L L L + N + + P LP L
Sbjct: 188 GLLGAQAKLERLLLHSNRLVS--LDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLP-NL 244
Query: 270 RALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA-----------------RVHHR- 311
+L L NH+A L + + + LT L L N LA R R
Sbjct: 245 SSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRT 304
Query: 312 ----AFRRLRALRSLDLA-GNQLTRLPMGLPTGLRTLQ---LQRNQLRMLEPEPLAGLDQ 363
AFR L LR L + +L+ LP G GL LQ L N L L L GL +
Sbjct: 305 LPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGK 364
Query: 364 LRELSLAHNRLR 375
LR++SL NRLR
Sbjct: 365 LRQVSLRRNRLR 376
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 107 bits (267), Expect = 2e-23
Identities = 110/367 (29%), Positives = 160/367 (43%), Gaps = 25/367 (6%)
Query: 40 LPRACPLRCSCP----RVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRL 95
L R CP C C + VDC L L P N++ +L L N + +L N L L
Sbjct: 30 LLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSL 89
Query: 96 SGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELY 155
L L L N ++ +P AF L L+ L + +NN + VP AL L+ L
Sbjct: 90 RFLEELRLAGNALTY--IPKGAFTGLYSLKVLML---QNNQLRHVPTEALQNLRSLQSLR 144
Query: 156 LQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILH---LGRNRIRQVE 212
L N + S + + FS LHSL +L L N LT +P R+L+ L L N+I +
Sbjct: 145 LDANHI--SYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIP 202
Query: 213 AARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP--RRLR 270
L L L +N++ S G L L TL L N LD P A+ L+
Sbjct: 203 DYAFGNLSSLVVLHLHNNRIHSLG--KKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLK 260
Query: 271 ALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAG-NQL 329
L N++ ++ + V P L ++ N + V AF+ L LR+L L G +Q+
Sbjct: 261 ELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQF--VGRSAFQHLPELRTLTLNGASQI 318
Query: 330 TRLP-MGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGP-GTWHEL 387
T P + L +L L Q+ L L L+ L L++N L D+ +L
Sbjct: 319 TEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLE--DLPSFSVCQKL 376
Query: 388 QALQVRH 394
Q + +RH
Sbjct: 377 QKIDLRH 383
Score = 84.0 bits (206), Expect = 2e-16
Identities = 92/327 (28%), Positives = 135/327 (41%), Gaps = 61/327 (18%)
Query: 72 RAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAH 131
R+ Q L L N + +P + S L LR L L +N ++ +P +AF SL+ LQ + +A
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTE--IPVQAFRSLSALQAMTLAL 195
Query: 132 NKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVP 191
NK I +P A + L L+L +N++ G F LHSLE LDL++N L P
Sbjct: 196 NK---IHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKC--FDGLHSLETLDLNYNNLDEFP 250
Query: 192 AGLPRTLAILHLG--RNRIRQV-------------------------------------- 211
+ + LG N IR +
Sbjct: 251 TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTL 310
Query: 212 ---------EAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVP 262
E L G L L L Q+ S LP L L L L N L+ +P
Sbjct: 311 TLNGASQITEFPDLTGTANLESLTLTGAQISS--LPQTVCNQLPNLQVLDLSYNLLEDLP 368
Query: 263 P-ALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRS 321
++ ++L+ + L HN + + L LNLA+N++A +H AF L +L
Sbjct: 369 SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAI--IHPNAFSTLPSLIK 426
Query: 322 LDLAGNQLTRLPMGLPTGLRTLQLQRN 348
LDL+ N L+ P+ GL L+L N
Sbjct: 427 LDLSSNLLSSFPITGLHGLTHLKLTGN 453
Score = 35.0 bits (79), Expect = 0.13
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 317 RALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRV 376
R L +D + L+ LP L L L N + L P PL L L EL LA N L
Sbjct: 45 RMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTY 104
Query: 377 GDIGPGT-WHELQALQVRHRLVSHTVPRA 404
G T + L+ L +++ + H A
Sbjct: 105 IPKGAFTGLYSLKVLMLQNNQLRHVPTEA 133
>gi|5901992 keratocan [Homo sapiens]
Length = 352
Score = 106 bits (265), Expect = 3e-23
Identities = 66/219 (30%), Positives = 110/219 (50%), Gaps = 2/219 (0%)
Query: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
+NNLI +P TQLR + L N++T+ G++ S+L L +L L N+L VP+
Sbjct: 79 QNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPS 138
Query: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
LPR+L L L RN++ ++ L L LQ+N+L + + L+ L L+
Sbjct: 139 PLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLN 198
Query: 253 LYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRA 312
+ N L +PP LP L L +N + + P + L L +N+L+ + R
Sbjct: 199 MAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRG 258
Query: 313 FRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLR 351
F + ++ L L+ NQLT++P + L+ L L N+++
Sbjct: 259 F-DVSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIK 295
Score = 103 bits (256), Expect = 4e-22
Identities = 87/322 (27%), Positives = 137/322 (42%), Gaps = 36/322 (11%)
Query: 44 CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101
CP+ C CP + C+ L+ P I +L LQNN ++ +P + LR +
Sbjct: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
Query: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRG 143
NL+ N I++ G+ A L +L L + N+ N +S++P+G
Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
Query: 144 ALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHL 203
S L L LQ+N+L D+ TF L +L L+++ N L +P LP L L
Sbjct: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
Query: 204 GRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPP 263
N I + + + +L L HN+L GLP+ + + L L N L +V P
Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHNQLTKV-P 278
Query: 264 ALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLD 323
+ L+ L L HN + ++ + +P + +F LR L
Sbjct: 279 RISAHLQHLHLDHNKIKSVNVSVICPSPSMLP------------AERDSFSYGPHLRYLR 326
Query: 324 LAGNQL-TRLPMGLPTGLRTLQ 344
L GN++ +PM L T R LQ
Sbjct: 327 LDGNEIKPPIPMALMTCFRLLQ 348
Score = 79.7 bits (195), Expect = 5e-15
Identities = 57/188 (30%), Positives = 85/188 (45%), Gaps = 1/188 (0%)
Query: 187 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 246
L +PA +P + L+L N I + A LR++ L N++ + G+ GAL L+
Sbjct: 63 LKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLK 121
Query: 247 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 306
L L L N L+ VP LPR L L L N V+ + LT L+L N+L
Sbjct: 122 KLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDN 181
Query: 307 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 366
F+ L+ L L++A N L +P LP L L N + + + ++
Sbjct: 182 AFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAF 241
Query: 367 LSLAHNRL 374
L L HN+L
Sbjct: 242 LRLNHNKL 249
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 104 bits (259), Expect = 2e-22
Identities = 107/387 (27%), Positives = 159/387 (41%), Gaps = 68/387 (17%)
Query: 41 PRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYN---------- 90
P C CSC VDC G L P+ ++ Q L + N + +LP +
Sbjct: 26 PPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEE 85
Query: 91 --------------ELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNL 136
LS L L+ L L NN + + +P EA L+ LQ L + N
Sbjct: 86 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT--VPSEAIRGLSALQSLRLDANH--- 140
Query: 137 ISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL-- 194
I+ VP + QLR L+L N LT+ + S L +L+ L L+ N+++++P
Sbjct: 141 ITSVPEDSFEGLVQLRHLWLDDNSLTE--VPVHPLSNLPTLQALTLALNKISSIPDFAFT 198
Query: 195 -PRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGS------------------- 234
+L +LHL N+IR + G L L L +N LG
Sbjct: 199 NLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSN 258
Query: 235 --SGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGAR------D 286
S +P GA L T+HLY N L V + L L + + GA +
Sbjct: 259 SISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDL----HSLVIRGASMVQQFPN 314
Query: 287 LVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP-MGLPTGLRTLQL 345
L T L L L +++S + + + + LR+LDL+ N + LP L + L
Sbjct: 315 LTGTVHLESLTLTGTKISS--IPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISL 372
Query: 346 QRNQLRMLEPEPLAGLDQLRELSLAHN 372
QRNQ+ ++ GL LR L L+ N
Sbjct: 373 QRNQIYQIKEGTFQGLISLRILDLSRN 399
Score = 81.6 bits (200), Expect = 1e-15
Identities = 98/369 (26%), Positives = 151/369 (40%), Gaps = 86/369 (23%)
Query: 77 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKN-- 134
L+LQNNQL+ +P + LS L++L L N I+S +P+++FE L QL+HL + N
Sbjct: 110 LTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS--VPEDSFEGLVQLRHLWLDDNSLTE 167
Query: 135 -------------------NLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLH 175
N IS +P A + + L L+L +N++ L F L
Sbjct: 168 VPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRS--LSQHCFDGLD 225
Query: 176 SLEYLDLSHNQLTTVPAGLPRTLAILHLG--RNRIRQVEAARLHGARGLRYLLLQHNQLG 233
+LE LDL++N L P + ++ LG N I + G LR + L N L
Sbjct: 226 NLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 285
Query: 234 SSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP--------------------------R 267
G A L LH+L + G + + P L +
Sbjct: 286 FVG--NSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQK 343
Query: 268 RLRALVLPHNHVAALGARDLVATPG---LTELNLAYNRLASAR----------------- 307
LR L L +N++ RDL + G L E++L N++ +
Sbjct: 344 MLRTLDLSYNNI-----RDLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSR 398
Query: 308 -----VHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLD 362
+H RAF L + +LD++ N+LT P GL L+L N ++ E
Sbjct: 399 NLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGN-FKLKEALAAKDFV 457
Query: 363 QLRELSLAH 371
LR LS+ +
Sbjct: 458 NLRSLSVPY 466
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/150 (30%), Positives = 62/150 (41%), Gaps = 31/150 (20%)
Query: 232 LGSSGLPAGALRPL-------RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 284
LGS+G P+GA PL G + G GL VP L +AL + N++ L
Sbjct: 16 LGSAG-PSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPE 74
Query: 285 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 344
P L EL LA N L+ +H +A L+ L+ L
Sbjct: 75 DAFKNFPFLEELQLAGNDLSF--IHPKALSGLKELK---------------------VLT 111
Query: 345 LQRNQLRMLEPEPLAGLDQLRELSLAHNRL 374
LQ NQL+ + E + GL L+ L L N +
Sbjct: 112 LQNNQLKTVPSEAIRGLSALQSLRLDANHI 141
Score = 38.5 bits (88), Expect = 0.012
Identities = 37/124 (29%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
Query: 55 TVDCDGLDLRVFPD-NITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGL 113
T+D ++R P N A + +SLQ NQ+ ++ L LR L+L NLI +
Sbjct: 347 TLDLSYNNIRDLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHE--I 404
Query: 114 PDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSK 173
AF +L + +L V+ N+ ++ P L+ QL+ L N L A F
Sbjct: 405 HSRAFATLGPITNLDVSFNE---LTSFPTEGLNGLNQLK---LVGNFKLKEALAAKDFVN 458
Query: 174 LHSL 177
L SL
Sbjct: 459 LRSL 462
Score = 38.1 bits (87), Expect = 0.015
Identities = 21/59 (35%), Positives = 36/59 (61%), Gaps = 3/59 (5%)
Query: 320 RSLDLAGNQLTRLPMGLPTG---LRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLR 375
++LD++ N +T+LP L LQL N L + P+ L+GL +L+ L+L +N+L+
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLK 118
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 104 bits (259), Expect = 2e-22
Identities = 90/302 (29%), Positives = 129/302 (42%), Gaps = 37/302 (12%)
Query: 37 LQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPY-NELSRL 95
L + ++CP C C + C+ L P I A L LQNNQ+ ++L L
Sbjct: 24 LSVMAKSCPSVCRCD-AGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNL 82
Query: 96 SGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELY 155
+ + L++N S + P + + +L H + N I + +LS+ L EL+
Sbjct: 83 LKVERIYLYHN--SLDEFPTNLPKYVKEL------HLQENNIRTITYDSLSKIPYLEELH 134
Query: 156 LQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAAR 215
L N ++ ++ F + L L LS N L+T+P GLPRT+ L L NRI + +
Sbjct: 135 LDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPS 194
Query: 216 LHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP-RRLRALVL 274
L G L+ L+L N L + GL L L L L N L P LP LR L L
Sbjct: 195 LQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYL 254
Query: 275 PHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPM 334
NH+ RV AF LR L LD++ N L+ LP
Sbjct: 255 QDNHI--------------------------NRVPPNAFSYLRQLYRLDMSNNNLSNLPQ 288
Query: 335 GL 336
G+
Sbjct: 289 GI 290
Score = 103 bits (257), Expect = 3e-22
Identities = 76/242 (31%), Positives = 110/242 (45%), Gaps = 5/242 (2%)
Query: 134 NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG 193
+ ++ +P G T L YLQ+NQ+ ++G+ + L +E + L HN L P
Sbjct: 46 DRFLTSIPTGIPEDATTL---YLQNNQINNAGIPSD-LKNLLKVERIYLYHNSLDEFPTN 101
Query: 194 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 253
LP+ + LHL N IR + L L L L N + + + GA R L L L
Sbjct: 102 LPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFL 161
Query: 254 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 313
N L +P LPR + L L N ++ + + L L L L N L + + + F
Sbjct: 162 SRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVF 221
Query: 314 RRLRALRSLDLAGNQLTRLPMGLP-TGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHN 372
L L L L N LT P+ LP T LR L LQ N + + P + L QL L +++N
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Query: 373 RL 374
L
Sbjct: 282 NL 283
Score = 86.7 bits (213), Expect = 4e-17
Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 2/181 (1%)
Query: 225 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 284
L LQ+NQ+ ++G+P+ L+ L + ++LY N LD P LP+ ++ L L N++ +
Sbjct: 63 LYLQNNQINNAGIPSD-LKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITY 121
Query: 285 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 344
L P L EL+L N +++ + AFR LR L L+ N L+ +P GLP + L+
Sbjct: 122 DSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR 181
Query: 345 LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRA 404
L N++ + L GL L+ L L N L +G + L L LV +++ A
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNL-TELSLVRNSLTAA 240
Query: 405 P 405
P
Sbjct: 241 P 241
Score = 35.4 bits (80), Expect = 0.098
Identities = 29/140 (20%), Positives = 50/140 (35%), Gaps = 43/140 (30%)
Query: 63 LRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLT 122
L P + R + L L +N++ + L L+ L+ L L NL+++ GL D+ F +L
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 123 QLQHLCVAHNK-------------------------------------------NNLISK 139
L L + N NN +S
Sbjct: 226 NLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSN 285
Query: 140 VPRGALSRQTQLRELYLQHN 159
+P+G + +L L++N
Sbjct: 286 LPQGIFDDLDNITQLILRNN 305
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 104 bits (259), Expect = 2e-22
Identities = 90/302 (29%), Positives = 129/302 (42%), Gaps = 37/302 (12%)
Query: 37 LQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPY-NELSRL 95
L + ++CP C C + C+ L P I A L LQNNQ+ ++L L
Sbjct: 24 LSVMAKSCPSVCRCD-AGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNL 82
Query: 96 SGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELY 155
+ + L++N S + P + + +L H + N I + +LS+ L EL+
Sbjct: 83 LKVERIYLYHN--SLDEFPTNLPKYVKEL------HLQENNIRTITYDSLSKIPYLEELH 134
Query: 156 LQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAAR 215
L N ++ ++ F + L L LS N L+T+P GLPRT+ L L NRI + +
Sbjct: 135 LDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPS 194
Query: 216 LHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP-RRLRALVL 274
L G L+ L+L N L + GL L L L L N L P LP LR L L
Sbjct: 195 LQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYL 254
Query: 275 PHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPM 334
NH+ RV AF LR L LD++ N L+ LP
Sbjct: 255 QDNHI--------------------------NRVPPNAFSYLRQLYRLDMSNNNLSNLPQ 288
Query: 335 GL 336
G+
Sbjct: 289 GI 290
Score = 103 bits (257), Expect = 3e-22
Identities = 76/242 (31%), Positives = 110/242 (45%), Gaps = 5/242 (2%)
Query: 134 NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG 193
+ ++ +P G T L YLQ+NQ+ ++G+ + L +E + L HN L P
Sbjct: 46 DRFLTSIPTGIPEDATTL---YLQNNQINNAGIPSD-LKNLLKVERIYLYHNSLDEFPTN 101
Query: 194 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 253
LP+ + LHL N IR + L L L L N + + + GA R L L L
Sbjct: 102 LPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFL 161
Query: 254 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 313
N L +P LPR + L L N ++ + + L L L L N L + + + F
Sbjct: 162 SRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVF 221
Query: 314 RRLRALRSLDLAGNQLTRLPMGLP-TGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHN 372
L L L L N LT P+ LP T LR L LQ N + + P + L QL L +++N
Sbjct: 222 FNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNN 281
Query: 373 RL 374
L
Sbjct: 282 NL 283
Score = 86.7 bits (213), Expect = 4e-17
Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 2/181 (1%)
Query: 225 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 284
L LQ+NQ+ ++G+P+ L+ L + ++LY N LD P LP+ ++ L L N++ +
Sbjct: 63 LYLQNNQINNAGIPSD-LKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITY 121
Query: 285 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ 344
L P L EL+L N +++ + AFR LR L L+ N L+ +P GLP + L+
Sbjct: 122 DSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELR 181
Query: 345 LQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRA 404
L N++ + L GL L+ L L N L +G + L L LV +++ A
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNL-TELSLVRNSLTAA 240
Query: 405 P 405
P
Sbjct: 241 P 241
Score = 35.4 bits (80), Expect = 0.098
Identities = 29/140 (20%), Positives = 50/140 (35%), Gaps = 43/140 (30%)
Query: 63 LRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLT 122
L P + R + L L +N++ + L L+ L+ L L NL+++ GL D+ F +L
Sbjct: 166 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 225
Query: 123 QLQHLCVAHNK-------------------------------------------NNLISK 139
L L + N NN +S
Sbjct: 226 NLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSN 285
Query: 140 VPRGALSRQTQLRELYLQHN 159
+P+G + +L L++N
Sbjct: 286 LPQGIFDDLDNITQLILRNN 305
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 102 bits (253), Expect = 9e-22
Identities = 89/267 (33%), Positives = 126/267 (47%), Gaps = 35/267 (13%)
Query: 73 AAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHN 132
A + L LQ NQLQ LP L+ L+TLNL NL++ LP+E F LT LQ L ++
Sbjct: 146 ALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQ--LPEELFHPLTSLQTLKLS-- 201
Query: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
NN +S +P+G + L+EL+L N +++ L FS+L LE L L N +T +P
Sbjct: 202 -NNALSGLPQGVFGKLGSLQELFLDSNNISE--LPPQVFSQLFCLERLWLQRNAITHLPL 258
Query: 193 GLPRTLA---ILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLH 249
+ +L L L N +R + A L L L HNQL + + G L L
Sbjct: 259 SIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLET--VAEGTFAHLSNLR 316
Query: 250 TLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVH 309
+L L N + +P + R L LV + LG+ +L A +H
Sbjct: 317 SLMLSYNAITHLPAGIFRDLEELVKLY-----LGSNNLTA------------------LH 353
Query: 310 HRAFRRLRALRSLDLAGNQLTRLPMGL 336
F+ L L L L+ NQLT LP G+
Sbjct: 354 PALFQNLSKLELLSLSKNQLTTLPEGI 380
Score = 85.1 bits (209), Expect = 1e-16
Identities = 106/365 (29%), Positives = 147/365 (40%), Gaps = 47/365 (12%)
Query: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103
CP+ C C V V C +L P +I +++ L L +
Sbjct: 22 CPMGCDC-FVQEVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRAFGSNPNLTKVVF 80
Query: 104 HNNLISSEGLPDEAFESLTQLQHLCVAHNKN-NLISKVPRGALSRQTQLRELYLQHNQLT 162
N + +AF L +L+ L V + NL + + S T L +L L N L
Sbjct: 81 LNTQLCQ--FRPDAFGGLPRLEDLEVTGSSFLNLSTNI----FSNLTSLGKLTLNFNML- 133
Query: 163 DSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL--PRT-LAILHLGRNRIRQVEAARLHGA 219
L F L +LE L L NQL +P L P T L L+L +N + Q+ H
Sbjct: 134 -EALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPL 192
Query: 220 RGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALV------ 273
L+ L L +N L SGLP G L L L L N + +PP + +L L
Sbjct: 193 TSLQTLKLSNNAL--SGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQR 250
Query: 274 -----LPHNHVAALGARDLVA----------------TPGLTELNLAYNRLASARVHHRA 312
LP + A+LG ++ TP L L+L +N+L + V
Sbjct: 251 NAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLET--VAEGT 308
Query: 313 FRRLRALRSLDLAGNQLTRLPMGLPTGLR---TLQLQRNQLRMLEPEPLAGLDQLRELSL 369
F L LRSL L+ N +T LP G+ L L L N L L P L +L LSL
Sbjct: 309 FAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSL 368
Query: 370 AHNRL 374
+ N+L
Sbjct: 369 SKNQL 373
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/194 (32%), Positives = 82/194 (42%), Gaps = 19/194 (9%)
Query: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
GLPR L L + + + L L L N L LP G + L L +LH
Sbjct: 95 GLPR-LEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNML--EALPEGLFQHLAALESLH 151
Query: 253 LYGNGLDRVPPALPRR-------LRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS 305
L GN L ALPRR L+ L L N +A L L L L+ N L+
Sbjct: 152 LQGNQLQ----ALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSG 207
Query: 306 ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ---LQRNQLRMLEPEPLAGLD 362
+ F +L +L+ L L N ++ LP + + L L+ LQRN + L A L
Sbjct: 208 --LPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLG 265
Query: 363 QLRELSLAHNRLRV 376
L LSL N LRV
Sbjct: 266 NLTFLSLQWNMLRV 279
>gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo
sapiens]
Length = 516
Score = 101 bits (252), Expect = 1e-21
Identities = 101/333 (30%), Positives = 152/333 (45%), Gaps = 28/333 (8%)
Query: 1 MGRPTQWPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDG 60
MG +WP G P +A + A + + L L ACP +C C ++ CD
Sbjct: 1 MGLHFKWPL--------GAPMLAAIY--AMSMVLKMLPALGMACPPKCRCEKL-LFYCDS 49
Query: 61 LDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFES 120
P+ + + LSL++N + EL ++ + S L L+L +N IS+ + ++AF+
Sbjct: 50 QGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQIST--VKEDAFQG 107
Query: 121 LTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 180
L +L+ L ++ NK I +P ++ L+ L L NQL S L F L L+ L
Sbjct: 108 LYKLKELILSSNK---IFYLPNTTFTQLINLQNLDLSFNQL--SSLHPELFYGLRKLQTL 162
Query: 181 DLSHNQLTTVPAGL---PRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGL 237
L N L T+P L R+L L L NR+R + G LR L L+HNQL
Sbjct: 163 HLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINF 222
Query: 238 PAGALRPLRGLHTLHLYGNGLDRVPPALP---RRLRALVLPHNHVAALGARDLVATPGLT 294
A LR L LHTL L N + + + L L L N + A+ P L
Sbjct: 223 -AHFLR-LSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLK 280
Query: 295 ELNLAYNRLASARVHHRAFRRLRALRSLDLAGN 327
L + N+L S + + LR+L ++ L+GN
Sbjct: 281 ILLMDNNKLNS--LDSKILNSLRSLTTVGLSGN 311
Score = 61.6 bits (148), Expect = 1e-09
Identities = 56/189 (29%), Positives = 85/189 (44%), Gaps = 28/189 (14%)
Query: 189 TVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGL 248
+VP + L L N I ++E + L +L L HNQ+ + A +GL
Sbjct: 54 SVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDA-----FQGL 108
Query: 249 HTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARV 308
+ +L+ L+L N + L L L+L++N+L+S +
Sbjct: 109 Y------------------KLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSS--L 148
Query: 309 HHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQ---LQRNQLRMLEPEPLAGLDQLR 365
H F LR L++L L N L +P+ L R+L+ L N+LR L AGL +LR
Sbjct: 149 HPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLR 208
Query: 366 ELSLAHNRL 374
EL L HN+L
Sbjct: 209 ELHLEHNQL 217
Score = 56.2 bits (134), Expect = 5e-08
Identities = 43/122 (35%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 257 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 316
G VP A + L L HNH+ L + LT L+L +N++++ V AF+ L
Sbjct: 51 GFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQIST--VKEDAFQGL 108
Query: 317 RALRSLDLAGNQLTRLPMGLPT---GLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 373
L+ L L+ N++ LP T L+ L L NQL L PE GL +L+ L L N
Sbjct: 109 YKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNS 168
Query: 374 LR 375
LR
Sbjct: 169 LR 170
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 101 bits (252), Expect = 1e-21
Identities = 115/352 (32%), Positives = 150/352 (42%), Gaps = 55/352 (15%)
Query: 4 PTQWPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDT-VDCDGLD 62
P P L+LLLL P + Q + CP C C V C +
Sbjct: 11 PLVLPLLVLLLLAP------------------ARQAAAQRCPQACICDNSRRHVACRYQN 52
Query: 63 LRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLT 122
L PD I Q L LQ N L+ +P + L L+L + E + + AF L
Sbjct: 53 LTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRH--CEVELVAEGAFRGLG 110
Query: 123 QLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDL 182
+L L +A +N + ++P+ AL LR L L+ N L + L TF L +L L+L
Sbjct: 111 RLLLLNLA---SNHLRELPQEALDGLGSLRRLELEGNALEE--LRPGTFGALGALATLNL 165
Query: 183 SHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGAL 242
+HN L +P A G +R+L L HN L S L AL
Sbjct: 166 AHNALVYLP---------------------AMAFQGLLRVRWLRLSHNAL--SVLAPEAL 202
Query: 243 RPLRGLHTLHLYGNGLDRVP-PAL--PRRLRALVLPHNHVAALGARDLVATPGLTELNLA 299
L L L L+ N L +P P L R L L L HN + G D +A PGL EL L
Sbjct: 203 AGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLD 262
Query: 300 YNRLASARVHHRAFRRLRALRSLDLAGNQLTRL-PMGLPTGLRTLQLQRNQL 350
L + + RAF L +LDL GNQL L P+ P LR L+LQ N L
Sbjct: 263 GGALQA--LGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPL 312
Score = 77.8 bits (190), Expect = 2e-14
Identities = 93/287 (32%), Positives = 117/287 (40%), Gaps = 66/287 (22%)
Query: 118 FESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSL 177
F S TQL L + N VPR A L L+LQH + + L+A + L L
Sbjct: 423 FPSDTQLLDL-----RRNHFPSVPRAAFPGLGHLVSLHLQHCGIAE--LEAGALAGLGRL 475
Query: 178 EYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGL 237
YL LS NQL AGL AA L GA L YL L+ N+ +
Sbjct: 476 IYLYLSDNQL----AGL-----------------SAAALEGAPRLGYLYLERNRFLQ--V 512
Query: 238 PAGALRPLRGLHTLHLYGNGLDRVPP---ALPRRLRALVLPHNHVAALGARDLVATPGLT 294
P ALR L L +LHL N +DR+ P R LR + L N + + L L
Sbjct: 513 PGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELE 572
Query: 295 ELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP--------------------- 333
+L+L N+L V A L AL L L+GN L L
Sbjct: 573 KLHLDRNQL--REVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGL 630
Query: 334 --------MGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHN 372
GL GL++L LQ+NQLR L P L QL + L+ N
Sbjct: 631 EQICPGAFSGLGPGLQSLHLQKNQLRALPALP--SLSQLELIDLSSN 675
Score = 72.8 bits (177), Expect = 6e-13
Identities = 72/195 (36%), Positives = 87/195 (44%), Gaps = 10/195 (5%)
Query: 187 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 246
L VP G P +L L RN V A G L L LQH G + L AGAL L
Sbjct: 416 LQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQH--CGIAELEAGALAGLG 473
Query: 247 GLHTLHLYGNGLDRVPPALPR---RLRALVLPHNHVAALGARDLVATPGLTELNLAYNRL 303
L L+L N L + A RL L L N + L A P L L+L N
Sbjct: 474 RLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDN-- 531
Query: 304 ASARVHHRAFRRLRALRSLDLAGNQLTRLPMGL---PTGLRTLQLQRNQLRMLEPEPLAG 360
A R+ R RALR + L+GN++T + +G L L L RNQLR + L G
Sbjct: 532 AVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEG 591
Query: 361 LDQLRELSLAHNRLR 375
L L EL L+ N LR
Sbjct: 592 LPALLELQLSGNPLR 606
Score = 71.2 bits (173), Expect = 2e-12
Identities = 80/248 (32%), Positives = 111/248 (44%), Gaps = 20/248 (8%)
Query: 137 ISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPR 196
+++VP A+ TQ L LQ N L + A F + L +LDL H ++ V G R
Sbjct: 53 LTEVP-DAIPELTQ--RLDLQGNLL--KVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFR 107
Query: 197 TLA---ILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 253
L +L+L N +R++ L G LR L L+ N L L G L L TL+L
Sbjct: 108 GLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEE--LRPGTFGALGALATLNL 165
Query: 254 YGNGLDRVPPALPR---RLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHH 310
N L +P + R+R L L HN ++ L L P L L+L +N L + +
Sbjct: 166 AHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQA--LPG 223
Query: 311 RAFRRLRALRSLDLAGNQLTRLP----MGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 366
+ R L L+L N LT + LP GLR L L L+ L P A +L
Sbjct: 224 PVLSQARGLARLELGHNPLTYAGEEDGLALP-GLRELLLDGGALQALGPRAFAHCPRLHT 282
Query: 367 LSLAHNRL 374
L L N+L
Sbjct: 283 LDLRGNQL 290
Score = 68.2 bits (165), Expect = 1e-11
Identities = 68/204 (33%), Positives = 89/204 (43%), Gaps = 28/204 (13%)
Query: 175 HSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGS 234
+S ++ + LT VP +P L L N ++ + AA G L +L L+H ++
Sbjct: 41 NSRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVEL 100
Query: 235 SGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLT 294
+ GA R L L L+L N L LP + LG+ L
Sbjct: 101 --VAEGAFRGLGRLLLLNLASNHLRE-------------LPQEALDGLGS--------LR 137
Query: 295 ELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGL---RTLQLQRNQLR 351
L L N L R F L AL +L+LA N L LP GL R L+L N L
Sbjct: 138 RLELEGNALEELRPG--TFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALS 195
Query: 352 MLEPEPLAGLDQLRELSLAHNRLR 375
+L PE LAGL LR LSL HN L+
Sbjct: 196 VLAPEALAGLPALRRLSLHHNELQ 219
Score = 64.7 bits (156), Expect = 2e-10
Identities = 85/330 (25%), Positives = 119/330 (36%), Gaps = 91/330 (27%)
Query: 18 GPPPVAGLEDAAFPHLGESLQPLPRACPLRCSC-PRVDTVDCDGLDLRVFPDNITRAAQH 76
GPP G E A P CP C C P C+G L+ P Q
Sbjct: 382 GPPRGPGEERAVAP------------CPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQL 429
Query: 77 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISS----------------------EGLP 114
L L+ N +P L L +L+L + I+ GL
Sbjct: 430 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLS 489
Query: 115 DEAFESLTQLQHLCVAHNK---------------------NNLISKVPRGALSRQTQLRE 153
A E +L +L + N+ +N + ++ G L R LR
Sbjct: 490 AAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRW 549
Query: 154 LYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEA 213
+YL N++T+ L A G R L LHL RN++R+V
Sbjct: 550 VYLSGNRITEVSLGA-----------------------LGPARELEKLHLDRNQLREVPT 586
Query: 214 ARLHGARGLRYLLLQHNQLGSSGLPAGALRPL-RGLHTLHLYGNGLDRVPP----ALPRR 268
L G L L L N L L GA +P+ R L L L +GL+++ P L
Sbjct: 587 GALEGLPALLELQLSGNPL--RALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPG 644
Query: 269 LRALVLPHNHVAALGARDLVATPGLTELNL 298
L++L L N + R L A P L++L L
Sbjct: 645 LQSLHLQKNQL-----RALPALPSLSQLEL 669
Score = 38.1 bits (87), Expect = 0.015
Identities = 89/318 (27%), Positives = 120/318 (37%), Gaps = 33/318 (10%)
Query: 73 AAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHN 132
A + LSL +N+LQ LP LS+ GL L L +N ++ G +E +L L+ L + +
Sbjct: 207 ALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG--EEDGLALPGLRELLL--D 262
Query: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
L + PR A + +L L L+ NQL T L L Q +
Sbjct: 263 GGALQALGPR-AFAHCPRLHTLDLRGNQL-------DTLPPLQGPGQLRRLRLQGNPLWC 314
Query: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
G + L R R+R A + G R LR L + P A + L
Sbjct: 315 GCQARPLLEWLARARVRSDGACQ--GPRRLRGEALDALRPWDLRCPGDAAQEEEELEERA 372
Query: 253 LYG-NGLDRVPPALPRRLRALV--------LPHNHVAALGARDLVATP-----GLTELNL 298
+ G R PP P RA+ +P + ++ L A P L+L
Sbjct: 373 VAGPRAPPRGPPRGPGEERAVAPCPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDL 432
Query: 299 AYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRT---LQLQRNQLRMLEP 355
N S V AF L L SL L + L G GL L L NQL L
Sbjct: 433 RRNHFPS--VPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSA 490
Query: 356 EPLAGLDQLRELSLAHNR 373
L G +L L L NR
Sbjct: 491 AALEGAPRLGYLYLERNR 508
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 101 bits (251), Expect = 1e-21
Identities = 123/430 (28%), Positives = 180/430 (41%), Gaps = 74/430 (17%)
Query: 1 MGRPTQWPSLLLL-LLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCD 59
+G P + P LLLL LLL PV P C C+C D++DC
Sbjct: 9 LGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAP------------CAAACTCAG-DSLDCG 55
Query: 60 GLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNN---LISSEGLPDE 116
G L P ++ + L+L N+L E+ L L+ + L+NN + S G
Sbjct: 56 GRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASS 115
Query: 117 AFESLTQLQH----------------LCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQ 160
SL LQH L V N I++V ++EL L N+
Sbjct: 116 HVVSLF-LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNR 174
Query: 161 LTDSGLDATTFSKL-HSLEYLDLSHNQLTTVPA---GLPRTLAILHLGRNRIRQVEAARL 216
+ L+ F L SL L LS N++T +P LPR L L L RNRIR +E
Sbjct: 175 I--GTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPR-LTQLDLNRNRIRLIEGLTF 231
Query: 217 HGARGLRYLLLQHNQLGSS------GLP----------------AGALRPLRGLHTLHLY 254
G L L LQ N + GL +G+L L LH LHL
Sbjct: 232 QGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLS 291
Query: 255 GNGLDRVPP---ALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHR 311
N + R+ + ++L LVL N++ L L L+ L L++N + + +
Sbjct: 292 NNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSI--SHIAEG 349
Query: 312 AFRRLRALRSLDLAGNQLTRL---PMGLPTGLRTLQ---LQRNQLRMLEPEPLAGLDQLR 365
AF+ LR+LR LDL N+++ G +GL +L L N+++ + +GL+ L
Sbjct: 350 AFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLE 409
Query: 366 ELSLAHNRLR 375
L+L N +R
Sbjct: 410 HLNLGGNAIR 419
Score = 50.4 bits (119), Expect = 3e-06
Identities = 51/160 (31%), Positives = 71/160 (44%), Gaps = 25/160 (15%)
Query: 77 LSLQNNQLQELPYNELSRLSGLRTLNLHNN-------------------LISSEGLPDEA 117
L L+ N L E+ L L+ L L+L NN ++S L
Sbjct: 264 LHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLD 323
Query: 118 FESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDAT-TFSKLHS 176
ESL +L L V +N IS + GA LR L L HN+++ + D + FS L S
Sbjct: 324 EESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDS 383
Query: 177 LEYLDLSHNQLTTVP----AGLPRTLAILHLGRNRIRQVE 212
L L L N++ +V +GL L L+LG N IR V+
Sbjct: 384 LSKLTLFGNKIKSVAKRAFSGL-EGLEHLNLGGNAIRSVQ 422
Score = 38.9 bits (89), Expect = 0.009
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 321 SLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL-RVGDI 379
SLD G L LP LP+ R+L L N+L ++P L L+E+ L +N L V +
Sbjct: 51 SLDCGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSL 110
Query: 380 GPGTWH 385
G + H
Sbjct: 111 GAASSH 116
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 100 bits (250), Expect = 2e-21
Identities = 76/268 (28%), Positives = 130/268 (48%), Gaps = 28/268 (10%)
Query: 44 CPLRCSC-PRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 102
CP C C RV V C L L P NI + L LQNN+++E+ N+ L+ L L
Sbjct: 75 CPFGCQCYSRV--VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLI 132
Query: 103 LHNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRGA 144
L+NN ++ + +AF + +L+ L ++HN+ N + K+ +
Sbjct: 133 LNNNKLTK--IHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 190
Query: 145 LSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLG 204
L L + N L ++G++ F + ++ ++ ++ +LT+VP GLP TL LHL
Sbjct: 191 FKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVPKGLPPTLLELHLD 249
Query: 205 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPA 264
N+I VE + L+ L L +N++ + + G+L + + +HL N L ++P
Sbjct: 250 YNKISTVELEDFKRYKELQRLGLGNNKI--TDIENGSLANIPRVREIHLENNKLKKIPSG 307
Query: 265 LP--RRLRALVLPHNHVAALGARDLVAT 290
LP + L+ + L N +A +G D T
Sbjct: 308 LPELKYLQIIFLHSNSIARVGVNDFCPT 335
Score = 71.6 bits (174), Expect = 1e-12
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Query: 251 LHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHH 310
+H GL VP +P R L L +N + + D L L L N+L ++H
Sbjct: 86 VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLT--KIHP 143
Query: 311 RAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLA 370
+AF + LR L L+ NQL+ +P+ LP L L++ N+++ ++ + G++ L L ++
Sbjct: 144 KAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMS 203
Query: 371 HNRLRVGDIGPGTWHELQALQVRHRLVSHT-VPRAPPSPCLPCHV 414
N L I PG + + +R T VP+ P L H+
Sbjct: 204 ANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHL 248
>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
sapiens]
Length = 581
Score = 99.8 bits (247), Expect = 4e-21
Identities = 103/337 (30%), Positives = 149/337 (44%), Gaps = 24/337 (7%)
Query: 37 LQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLS 96
L R CP C C V C+ L+ P +I+ LSL+ N LQ+L YN+ L+
Sbjct: 27 LSSAERGCPKGCRCEG-KMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLN 85
Query: 97 GLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYL 156
L L L +N IS+ + + AF + +L+ L ++ N+ IS T LR L L
Sbjct: 86 QLTWLYLDHNHISN--IDENAFNGIRRLKELILSSNR---ISYFLNNTFRPVTNLRNLDL 140
Query: 157 QHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGL---PRTLAILHLGRNRIRQVEA 213
+NQL L + F L L L L N L T+P + R L +L LG NRIR +
Sbjct: 141 SYNQL--HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLAR 198
Query: 214 ARLHGARGLRYLLLQHNQLGSSGLPAGALRP-LRGLHTLHLYGNGLDRVPPALP---RRL 269
G L+ L L+HNQ L AL P L L L+L N + + + L
Sbjct: 199 NVFAGMIRLKELHLEHNQFSKLNL---ALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSL 255
Query: 270 RALVLPHNHVAAL-GARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGN- 327
+ L L N + A G P L LNL N+L + +L + LAGN
Sbjct: 256 QRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTF--IGQEILDSWISLNDISLAGNI 313
Query: 328 -QLTRLPMGLPTGLRTLQ-LQRNQLRMLEPEPLAGLD 362
+ +R L L++ + L+ N + P+ L G++
Sbjct: 314 WECSRNICSLVNWLKSFKGLRENTIICASPKELQGVN 350
Score = 58.9 bits (141), Expect = 8e-09
Identities = 53/191 (27%), Positives = 85/191 (44%), Gaps = 28/191 (14%)
Query: 186 QLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPL 245
+L +P+ + L L N +++++ + G L +L L HN + S + A
Sbjct: 51 KLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHI--SNIDENAF--- 105
Query: 246 RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS 305
NG+ RRL+ L+L N ++ L L+L+YN+L S
Sbjct: 106 ----------NGI--------RRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHS 147
Query: 306 ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQR---NQLRMLEPEPLAGLD 362
+ FR LR L SL L N L +P+ + R L+L N++R L AG+
Sbjct: 148 --LGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 363 QLRELSLAHNR 373
+L+EL L HN+
Sbjct: 206 RLKELHLEHNQ 216
Score = 30.4 bits (67), Expect = 3.1
Identities = 16/47 (34%), Positives = 24/47 (51%)
Query: 328 QLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRL 374
+L +P + G L L+ N L+ L+ GL+QL L L HN +
Sbjct: 51 KLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHI 97
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,399,858
Number of Sequences: 37866
Number of extensions: 831583
Number of successful extensions: 5496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 127
Number of HSP's that attempted gapping in prelim test: 2525
Number of HSP's gapped (non-prelim): 1169
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.