BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|226246665 keratin 72 isoform 2 [Homo sapiens] (469 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|226246665 keratin 72 isoform 2 [Homo sapiens] 912 0.0 gi|28372503 keratin 72 isoform 1 [Homo sapiens] 891 0.0 gi|226246663 keratin 72 isoform 1 [Homo sapiens] 891 0.0 gi|28173564 keratin 73 [Homo sapiens] 621 e-178 gi|15618995 keratin 71 [Homo sapiens] 618 e-177 gi|148612803 keratin 6 irs4 [Homo sapiens] 602 e-172 gi|5031839 keratin 6A [Homo sapiens] 487 e-137 gi|109255249 keratin 4 [Homo sapiens] 486 e-137 gi|119703753 keratin 6B [Homo sapiens] 486 e-137 gi|155969697 keratin 6C [Homo sapiens] 485 e-137 gi|153791158 keratin 75 [Homo sapiens] 468 e-132 gi|119395754 keratin 5 [Homo sapiens] 468 e-132 gi|109148552 keratin 3 [Homo sapiens] 462 e-130 gi|153791670 keratin 76 [Homo sapiens] 456 e-128 gi|32567786 keratin 6L [Homo sapiens] 451 e-127 gi|47132620 keratin 2 [Homo sapiens] 451 e-127 gi|119395750 keratin 1 [Homo sapiens] 446 e-125 gi|194018511 keratin 77 [Homo sapiens] 427 e-120 gi|89357932 keratin 5b [Homo sapiens] 397 e-111 gi|4504919 keratin 8 [Homo sapiens] 397 e-110 gi|67782365 keratin 7 [Homo sapiens] 396 e-110 gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 367 e-101 gi|4504935 keratin 85 [Homo sapiens] 349 3e-96 gi|27477127 keratin 82 [Homo sapiens] 345 4e-95 gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 336 3e-92 gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 335 5e-92 gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 335 5e-92 gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 335 5e-92 gi|14318422 keratin 86 [Homo sapiens] 335 5e-92 gi|169790841 keratin 83 [Homo sapiens] 331 8e-91 >gi|226246665 keratin 72 isoform 2 [Homo sapiens] Length = 469 Score = 912 bits (2356), Expect = 0.0 Identities = 469/469 (100%), Positives = 469/469 (100%) Query: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL Sbjct: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60 Query: 61 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR Sbjct: 61 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120 Query: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI Sbjct: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180 Query: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY Sbjct: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240 Query: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR Sbjct: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300 Query: 301 AQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEE 360 AQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEE Sbjct: 301 AQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEE 360 Query: 361 LARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAG 420 LARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAG Sbjct: 361 LARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAG 420 Query: 421 FSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 469 FSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR Sbjct: 421 FSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 469 >gi|28372503 keratin 72 isoform 1 [Homo sapiens] Length = 511 Score = 891 bits (2303), Expect = 0.0 Identities = 469/511 (91%), Positives = 469/511 (91%), Gaps = 42/511 (8%) Query: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL Sbjct: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60 Query: 61 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR Sbjct: 61 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120 Query: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI Sbjct: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180 Query: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY Sbjct: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240 Query: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR Sbjct: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300 Query: 301 AQYEEIALKSKAEAETLYQTK--------------------------------------- 321 AQYEEIALKSKAEAETLYQTK Sbjct: 301 AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV 360 Query: 322 ---CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 378 CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL Sbjct: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420 Query: 379 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 438 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA Sbjct: 421 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 480 Query: 439 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 469 DVKTKGSCGSELKDPLAKTSGSSCATKKASR Sbjct: 481 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 511 >gi|226246663 keratin 72 isoform 1 [Homo sapiens] Length = 511 Score = 891 bits (2303), Expect = 0.0 Identities = 469/511 (91%), Positives = 469/511 (91%), Gaps = 42/511 (8%) Query: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL Sbjct: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60 Query: 61 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR Sbjct: 61 SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120 Query: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI Sbjct: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180 Query: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY Sbjct: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240 Query: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR Sbjct: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300 Query: 301 AQYEEIALKSKAEAETLYQTK--------------------------------------- 321 AQYEEIALKSKAEAETLYQTK Sbjct: 301 AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV 360 Query: 322 ---CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 378 CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL Sbjct: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420 Query: 379 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 438 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA Sbjct: 421 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 480 Query: 439 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 469 DVKTKGSCGSELKDPLAKTSGSSCATKKASR Sbjct: 481 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 511 >gi|28173564 keratin 73 [Homo sapiens] Length = 540 Score = 621 bits (1602), Expect = e-178 Identities = 348/543 (64%), Positives = 390/543 (71%), Gaps = 77/543 (14%) Query: 1 MSRQLTHFP-RGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58 MSRQ T+ + GFSGCSAVLSGG SS+S+RA KG S F S+SL LGG+RS+ Sbjct: 1 MSRQFTYKSGAAAKGGFSGCSAVLSGG---SSSSYRAGGKGLSGGFSSRSLYSLGGARSI 57 Query: 59 ALSAAARRGG--------GRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPL 110 + + A+ G GR GF G+ FGS LG CPS+CPPGGI QVT+NKSLLAPL Sbjct: 58 SFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPL 117 Query: 111 NVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRK 170 NVE+DPEIQ+VRAQEREQIK LNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ Sbjct: 118 NVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKN 177 Query: 171 NLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFV 230 NLEPI EGYISNL+KQLE LSGD VRLDSELR+++++VEDYKKRYE EIN+RT AENEFV Sbjct: 178 NLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFV 237 Query: 231 VLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDL 290 VLKKDVDAAY +KVELQAKVD+L EIKFFKCLYEGE QIQSHISDTSI+LSMDNNR+L Sbjct: 238 VLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNL 297 Query: 291 DLDSIIAEVRAQYEEIALKSKAEAETLYQTK----------------------------- 321 DLDSIIAEVRAQYEEIA KSKAEAE LYQTK Sbjct: 298 DLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLI 357 Query: 322 -------------CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREY 368 CA+LETAIADAEQRGDCALKDARAKLDELEGAL QAKEELARMLREY Sbjct: 358 QRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREY 417 Query: 369 QELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGAS 428 QEL+S+KL+LD+EIATYRKLLE EECRMSGEY NSVSISVI+S+ AG G G GF + Sbjct: 418 QELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNA 477 Query: 429 SSYSYKTAA----------------------ADVKTKGSCGSELKDPLAKTSGSSCATKK 466 +Y Y ++ + +T+ SE +D KT S TKK Sbjct: 478 GTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKK 537 Query: 467 ASR 469 R Sbjct: 538 TMR 540 >gi|15618995 keratin 71 [Homo sapiens] Length = 523 Score = 618 bits (1594), Expect = e-177 Identities = 352/528 (66%), Positives = 396/528 (75%), Gaps = 64/528 (12%) Query: 1 MSRQLT-HFPRGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58 MSRQ T + GFSGCSAVLSGG SS+SFRA KG S FGS+SL LGG RSL Sbjct: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGG---SSSSFRAGSKGLSGGFGSRSLYSLGGVRSL 57 Query: 59 ALSAAARRGGG------RLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNV 112 +++ + + GG R GF G+ FGS LGP CP+VCPPGGI QVTVN+SLLAPLNV Sbjct: 58 NVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNV 117 Query: 113 EMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNL 172 E+DPEIQ+VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ NL Sbjct: 118 ELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNL 177 Query: 173 EPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVL 232 EPI EGYISNL+KQLE LSGD VRLDSELRN++D+VEDYKKRYE EIN+RTAAENEFV+L Sbjct: 178 EPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLL 237 Query: 233 KKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDL 292 KKDVDAAY NKVELQAKV+S+ EIKFF+CL+E EITQIQSHISD S++LSMDNNR+LDL Sbjct: 238 KKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDL 297 Query: 293 DSIIAEVRAQYEEIALKSKAEAETLYQTK------------------------------- 321 DSII EVR QYEEIALKSKAEAE LYQTK Sbjct: 298 DSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQR 357 Query: 322 -----------CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQE 370 ++LETAIADAEQRGD ALKDARAKLDELEGALHQAKEELARMLREYQE Sbjct: 358 IRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQE 417 Query: 371 LVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF-----SMGF 425 L+SLKLALDMEIATYRKLLESEECRMSGE+P+ VSIS+ISST+ G+ GF S G+ Sbjct: 418 LMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGS-VYGFRPSMVSGGY 476 Query: 426 GASSSYSY----KTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 469 A+SS + +++GS ++ KD L K S S +KK SR Sbjct: 477 VANSSNCISGVCSVRGGEGRSRGS-ANDYKDTLGKGSSLSAPSKKTSR 523 >gi|148612803 keratin 6 irs4 [Homo sapiens] Length = 529 Score = 602 bits (1551), Expect = e-172 Identities = 341/529 (64%), Positives = 381/529 (72%), Gaps = 60/529 (11%) Query: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGS-ASFGSKSLSCLGGSRSLA 59 MSRQL G++ FS SAV+ S AS+ A +G+ A FGS+SL LGG+R ++ Sbjct: 1 MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS 60 Query: 60 LSAA--------------ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKS 105 + A + GGGR GF G+ FGS LGP C SVCPPGGI QVTVNKS Sbjct: 61 FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS 120 Query: 106 LLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDL 165 LLAPLNVE+DPEIQ+VRAQEREQIK LN+KFASFIDKVRFLEQQNQVLETKW LLQQLDL Sbjct: 121 LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL 180 Query: 166 NNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225 NNC+KNLEPI EGYISNL+KQLE LSGD VRLDSELR+M+DLVEDYKKRYEVEINRRT A Sbjct: 181 NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA 240 Query: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285 ENEFVVLKKD DAAY KVELQAKVDSL EIKF KCLY+ EI QIQ+H S+TS++LSMD Sbjct: 241 ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD 300 Query: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKC----------------------- 322 NNRDLDLDSIIAEVR YEEIALKSKAEAE LYQTK Sbjct: 301 NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE 360 Query: 323 -------------------ADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELAR 363 A LETAIADAEQRGD ALKDA+AKLDELEGALHQAKEELAR Sbjct: 361 LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR 420 Query: 364 MLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAG---AGGAG 420 MLREYQEL+SLKLALDMEIATYRKLLE EECRMSGE P+SVSISVISS++ AG Sbjct: 421 MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG 480 Query: 421 FSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 469 +G A + S T + KT + G +LKD K++ +S +KA+R Sbjct: 481 VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529 >gi|5031839 keratin 6A [Homo sapiens] Length = 564 Score = 487 bits (1253), Expect = e-137 Identities = 284/538 (52%), Positives = 347/538 (64%), Gaps = 80/538 (14%) Query: 2 SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61 S P R GFS S S G G + G A FGS+SL LGGS+ +++ Sbjct: 19 SANSARLPGVSRSGFSSVSVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73 Query: 62 AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94 + R GG G G G+ FG AGL GP P VCPP Sbjct: 74 GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132 Query: 95 GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154 GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLE Sbjct: 133 GGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLE 192 Query: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214 TKW LLQ+ R+NLEP++E YI+NL++QL+ + G+ RLDSELR MQDLVED+K + Sbjct: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNK 252 Query: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274 YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312 Query: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK------------- 321 ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372 Query: 322 -----------------------------CADLETAIADAEQRGDCALKDARAKLDELEG 352 CA+L+ AIADAEQRG+ ALKDA+ KL+ LE Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLED 432 Query: 353 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 412 AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE V+ISV+ ST Sbjct: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQST 492 Query: 413 ----NAGAGGAGFSMGFGASSSYSYKTA-AADVKTKGSCGSELKDPLAKTSGSSCATK 465 GA G G +G G SSYSY + S G + L+ G S K Sbjct: 493 VSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIK 550 >gi|109255249 keratin 4 [Homo sapiens] Length = 594 Score = 486 bits (1250), Expect = e-137 Identities = 280/482 (58%), Positives = 332/482 (68%), Gaps = 62/482 (12%) Query: 10 RGERLGFSGCSAVLSGG----IGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAAR 65 RG GFS SA++ GG S S S A S FGS+SL L G++S+++S A Sbjct: 83 RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142 Query: 66 R-----------GGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEM 114 R G G GG G +F G GP P VCP GGI +VT+N+SLL PL+VE+ Sbjct: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKG-GPGFP-VCPAGGIQEVTINQSLLTPLHVEI 200 Query: 115 DPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEP 174 DPEIQ+VR +EREQIK LNNKFASFIDKV+FLEQQN+VLETKWNLLQQ KNLEP Sbjct: 201 DPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEP 260 Query: 175 IYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKK 234 ++E Y+S L+KQL+ L D RL SEL+ MQD VED+K +YE EIN+RTAAEN+FVVLKK Sbjct: 261 LFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKK 320 Query: 235 DVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDS 294 DVDAAY+NKVEL+AKVDSL DEI F K LY+ E++Q+Q+H+SDTS+VLSMDNNR+LDLDS Sbjct: 321 DVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDS 380 Query: 295 IIAEVRAQYEEIALKSKAEAETLYQTK--------------------------------- 321 IIAEVRAQYEEIA +SKAEAE LYQTK Sbjct: 381 IIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLR 440 Query: 322 ---------CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELV 372 C L+ ++ADAEQRG+ ALKDA +K ELE AL QAKEELARMLREYQEL+ Sbjct: 441 AEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELM 500 Query: 373 SLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS---STNAGAGGAGFSMGFGASS 429 S+KLALD+EIATYRKLLE EE RMSGE ++VSISV+S ST +GG G GFG SS Sbjct: 501 SVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSS 560 Query: 430 SY 431 + Sbjct: 561 GF 562 >gi|119703753 keratin 6B [Homo sapiens] Length = 564 Score = 486 bits (1250), Expect = e-137 Identities = 278/505 (55%), Positives = 338/505 (66%), Gaps = 79/505 (15%) Query: 2 SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61 S P R GFS S S G G + G A FGS+SL LGGS+ +++ Sbjct: 19 SANSARLPGVSRSGFSSISVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73 Query: 62 AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94 + R GG G G G+ FG AGL GP P VCPP Sbjct: 74 GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132 Query: 95 GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154 GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VL+ Sbjct: 133 GGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLD 192 Query: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214 TKW LLQ+ R+NLEP++E YI+NL++QL+ + G+ RLDSELRNMQDLVED K + Sbjct: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNK 252 Query: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274 YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312 Query: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK------------- 321 ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGD 372 Query: 322 -----------------------------CADLETAIADAEQRGDCALKDARAKLDELEG 352 CA+L+ AIADAEQRG+ ALKDA+ KL+ LE Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLED 432 Query: 353 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 412 AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE V+ISV+ ST Sbjct: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQST 492 Query: 413 ----NAGAGGAGFSMGFGASSSYSY 433 GA G G +G G SSYSY Sbjct: 493 VSSGYGGASGVGSGLGLGGGSSYSY 517 >gi|155969697 keratin 6C [Homo sapiens] Length = 564 Score = 485 bits (1249), Expect = e-137 Identities = 277/505 (54%), Positives = 337/505 (66%), Gaps = 79/505 (15%) Query: 2 SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61 S P R GFS S S G G + G A FGS+SL LGGS+ +++ Sbjct: 19 SANSARLPGVSRSGFSSISVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73 Query: 62 AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94 + R GG G G G+ FG AGL GP P VCPP Sbjct: 74 GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132 Query: 95 GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154 GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VL+ Sbjct: 133 GGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLD 192 Query: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214 TKW LLQ+ R+NLEP++E YI+NL++QL+ + G+ RLDSELRNMQDLVED K + Sbjct: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNK 252 Query: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274 YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312 Query: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK------------- 321 ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372 Query: 322 -----------------------------CADLETAIADAEQRGDCALKDARAKLDELEG 352 CA L+ AIADAEQRG+ ALKDA+ KL+ LE Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLED 432 Query: 353 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 412 AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE V++SV+ ST Sbjct: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQST 492 Query: 413 ----NAGAGGAGFSMGFGASSSYSY 433 GA G G +G G SSYSY Sbjct: 493 ISSGYGGASGVGSGLGLGGGSSYSY 517 >gi|153791158 keratin 75 [Homo sapiens] Length = 551 Score = 468 bits (1204), Expect = e-132 Identities = 278/538 (51%), Positives = 357/538 (66%), Gaps = 73/538 (13%) Query: 1 MSRQLT-HFPRGERLGFSGCSAVL--SGGIGSSSASFRARVKGS----------ASFGSK 47 MSRQ + F G R GFS SA+ +G SS S GS ASFGS+ Sbjct: 1 MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60 Query: 48 SLSCLGGSRSLALS---AAARRG-GGRLGGFVG--TAFGSAG------LGPKCPSVCPPG 95 SL LGG++ ++++ ++ R G GGR G + FG G GP P VCPPG Sbjct: 61 SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFP-VCPPG 119 Query: 96 GIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLET 155 GI +VTVN+SLL PL++++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLET Sbjct: 120 GIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLET 179 Query: 156 KWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRY 215 KW LLQ+ R+NLEP+++ Y S L++QLE ++ + RL++ELRNMQD+VED+K RY Sbjct: 180 KWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRY 239 Query: 216 EVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHI 275 E EIN+RTAAENEFV LKKDVDAAYMNKVEL+AKV SL +EI F +++ E++Q+Q+ + Sbjct: 240 EDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQV 299 Query: 276 SDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK-------------- 321 DTS+VLSMDNNR+LDLDSIIAEV+AQYE+IA +S+AEAE+ YQTK Sbjct: 300 GDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDD 359 Query: 322 ----------------------------CADLETAIADAEQRGDCALKDARAKLDELEGA 353 C+ L+TAIADAEQRG+ ALKDARAKL +LE A Sbjct: 360 LRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEA 419 Query: 354 LHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTN 413 L +AK+++AR+LREYQEL+++KLALD+EIATYRKLLE EECR+SGE + V+ISV++ST Sbjct: 420 LQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTL 479 Query: 414 AGAGGAGFS-----MGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKK 466 + G+G S +G G S YS+ T+ G GS + G S ++ K Sbjct: 480 SSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537 >gi|119395754 keratin 5 [Homo sapiens] Length = 590 Score = 468 bits (1203), Expect = e-132 Identities = 265/490 (54%), Positives = 328/490 (66%), Gaps = 73/490 (14%) Query: 9 PRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARR-- 66 P R F+ S GG G A G +GS+SL LGGS+ +++S + Sbjct: 25 PSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFR 84 Query: 67 -----------------------GGGRLGGFV---GTAFGSAGLGPKCPSVCPPGGIPQV 100 GGG GGF G FG GP P VCPPGGI +V Sbjct: 85 NRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFP-VCPPGGIQEV 143 Query: 101 TVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLL 160 TVN+SLL PLN+++DP IQRVR +EREQIK LNNKFASFIDKVRFLEQQN+VL+TKW LL Sbjct: 144 TVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLL 203 Query: 161 QQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEIN 220 Q+ R+NLEP++E YI+NL++QL+ + G+ RLDSELRNMQDLVED+K +YE EIN Sbjct: 204 QEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEIN 263 Query: 221 RRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSI 280 +RT AENEFV+LKKDVDAAYMNKVEL+AKVD+L DEI F K ++ E++Q+Q+H+SDTS+ Sbjct: 264 KRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSV 323 Query: 281 VLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK------------------- 321 VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+ EAE+ YQTK Sbjct: 324 VLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTK 383 Query: 322 -----------------------CADLETAIADAEQRGDCALKDARAKLDELEGALHQAK 358 CA+L+ AIADAEQRG+ ALKDAR KL ELE AL +AK Sbjct: 384 HEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAK 443 Query: 359 EELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI-SSTNAGAG 417 +++AR+LREYQEL++ KLALD+EIATYRKLLE EECR+SGE V+ISV+ SS ++G G Sbjct: 444 QDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYG 503 Query: 418 -GAGFSMGFG 426 G+G+ G G Sbjct: 504 SGSGYGGGLG 513 >gi|109148552 keratin 3 [Homo sapiens] Length = 628 Score = 462 bits (1189), Expect = e-130 Identities = 279/546 (51%), Positives = 342/546 (62%), Gaps = 123/546 (22%) Query: 1 MSRQLTHFPRGERLGFSGCSAVLSG-----------GIGSSSASFRARVKGSASFGSKSL 49 MSRQ + G GFSG SAV+SG G G + FR+ G+ FGS+SL Sbjct: 1 MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRS---GAGGFGSRSL 57 Query: 50 SCLGGSRSLALSAAA---RRGG-------------------------------------- 68 LGG++S+++S AA R GG Sbjct: 58 YNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGG 117 Query: 69 --------GRLGGFVGTAF--------GSAGLGPKCPSVCP--------PGGIPQVTVNK 104 G GGF G GS G G P PGGI +VT+N+ Sbjct: 118 GFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQ 177 Query: 105 SLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLD 164 SLL PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKWNLLQQ Sbjct: 178 SLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQG 237 Query: 165 LNNCR--KNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRR 222 ++ NLEP++E +I+ L+ L+ + G+ RLDSEL+NM+DLVED+KK+YE EIN+R Sbjct: 238 TSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKR 297 Query: 223 TAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVL 282 TAAENEFV LKKDVD+AYMNKVELQAKVD+L DEI F + LY+ E++Q+QSHISDTS+VL Sbjct: 298 TAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVL 357 Query: 283 SMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKC-------------------- 322 SMDNNR LDLDSIIAEVRAQYE+IA +SKAEAE LYQTK Sbjct: 358 SMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSE 417 Query: 323 ----------------------ADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEE 360 A+L+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++ Sbjct: 418 IIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDD 477 Query: 361 LARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAG 420 LAR+LR+YQEL+++KLALD+EIATYRKLLE EE RMSGE P++VSISV+SS+ A G Sbjct: 478 LARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGG 537 Query: 421 FSMGFG 426 + G+G Sbjct: 538 YGGGYG 543 >gi|153791670 keratin 76 [Homo sapiens] Length = 638 Score = 456 bits (1174), Expect = e-128 Identities = 282/540 (52%), Positives = 345/540 (63%), Gaps = 109/540 (20%) Query: 11 GERLGFSGCSAVLSG-----------GIGSSSASFRARVKGSASFGSKSLSCLGGSRSLA 59 G GFSG SAV+SG G G + FR+ G+ SFGS+SL LG ++S++ Sbjct: 12 GRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRS---GAGSFGSRSLYNLGSNKSIS 68 Query: 60 LSAAARR------GGGRL-----------------GGF-----VGTAFGSAGL-----GP 86 +S AA GGGR GGF VG+ FG AG G Sbjct: 69 ISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGF 128 Query: 87 KCPSVCP----------------PGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIK 130 P V PGGI +V VN+SLL PLNVE+DP+I +V+AQEREQIK Sbjct: 129 GGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIK 188 Query: 131 ALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEML 190 LNNKFASFIDKVRFLEQQN+VLETKW LLQQ + +LEP +E YIS L KQL+ L Sbjct: 189 TLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQLDSL 248 Query: 191 SGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKV 250 G+ L+ EL++MQDLVED+KK+YE EIN+RTAAENEFV LKKDVDAA+MNKVELQAKV Sbjct: 249 LGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQAKV 308 Query: 251 DSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKS 310 DSLTDE+ F + LYE E++Q+QSH SDTS+VLSMDNNR LDL SIIAEVRAQYEEIA +S Sbjct: 309 DSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIAQRS 368 Query: 311 KAEAETLYQTKC------------------------------------------ADLETA 328 K+EAE LYQTK A+L+TA Sbjct: 369 KSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANLQTA 428 Query: 329 IADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKL 388 IA+AEQRG+ ALKDA AKL +L+ AL +AK++LAR+LR+YQEL+++KLALD+EIATYRKL Sbjct: 429 IAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKL 488 Query: 389 LESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMG-FG---ASSSYSYKTAAADVKTKG 444 LE EECRMSGE ++V ISV+S+ + +G +G S G FG S S YK ++ + G Sbjct: 489 LEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSG 548 Score = 32.7 bits (73), Expect = 0.73 Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 3/89 (3%) Query: 10 RGERLGFSGC-SAVLSGGIGSSSASFRARVKGSAS-FGSKSLSCLGGSRSLALSAAARRG 67 RG G SG S GG SSS+S GS S +G S GG R + S + Sbjct: 523 RGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGG-RGSSGSYQSSSS 581 Query: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGG 96 G RLGG + +G+G S+ GG Sbjct: 582 GSRLGGAGSISVSHSGMGSSSGSIQTSGG 610 >gi|32567786 keratin 6L [Homo sapiens] Length = 535 Score = 451 bits (1160), Expect = e-127 Identities = 266/494 (53%), Positives = 332/494 (67%), Gaps = 75/494 (15%) Query: 1 MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVK---------------GSASFG 45 +SRQ T+ +G GFS SA SGG GS + + + V G+ FG Sbjct: 5 VSRQ-TYSTKG---GFSSNSA--SGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFG 58 Query: 46 SKSLSCLGGSRSLALSAAARRGGGRLG------GFVGTAFGSAGLGPKC-PSVCPPGGIP 98 S+SL LGG +S+++S A GG LG GF AF G G + CPPGGI Sbjct: 59 SRSLYNLGGHKSISVSVA---GGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQ 115 Query: 99 QVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWN 158 +VTVN+SLL PL+VE+DPEIQRVR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW Sbjct: 116 EVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWA 175 Query: 159 LLQQL--DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216 LLQ+ +L R NLEP++E Y+ +++ L+ L + RLDSELRN+QDLVED+K +YE Sbjct: 176 LLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYE 235 Query: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276 EIN+ TAAENEFVVLKKDVDAAYM +++L KV +LT EI F + LYE E++Q+Q+H+S Sbjct: 236 DEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVS 295 Query: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK--------------- 321 +T++VLSMDNNR+LDLDSIIAEV+AQYE IA +S+AEAE YQTK Sbjct: 296 NTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNL 355 Query: 322 ---------------------------CADLETAIADAEQRGDCALKDARAKLDELEGAL 354 C L+TAIA+AEQRG+ ALKDA+ KL +L+ AL Sbjct: 356 RDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVAL 415 Query: 355 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA 414 HQAKE+L R+LR+YQEL+++KLALD+EIATYRKLLESEE RMSGE P++VSISV ++ Sbjct: 416 HQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTT 475 Query: 415 GAGGAGFSMGFGAS 428 GG S G G S Sbjct: 476 VCGGGAASFGGGIS 489 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 451 bits (1160), Expect = e-127 Identities = 270/537 (50%), Positives = 339/537 (63%), Gaps = 108/537 (20%) Query: 15 GFSGCSAVLSGGIGSSSASFRARVK--------GSASFGSKSLSCLGGSRSLALSAAARR 66 GFS SAV+SGG S++SF + G FGS+SL LGG++S+++S A Sbjct: 21 GFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGG 80 Query: 67 GG--------------------------------------GRLGGF-----VGTAFGSAG 83 GG GR GGF VG G G Sbjct: 81 GGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGG 140 Query: 84 LGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143 GP PGGI +V+VN+SLL PLNV++DPEIQ V+AQEREQIK LNNKFASFIDKV Sbjct: 141 FGPGGY----PGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196 Query: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203 RFLEQQNQVL+TKW LLQQ+++ NLEPI++GYI +L++ L+ L+ + +SEL N Sbjct: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256 Query: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263 MQDLVEDYKK+YE EIN+RTAAEN+FV LKKDVD AYM KVELQ+KVD L EI+F K L Sbjct: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316 Query: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK-- 321 Y+ EI+QI ++DT+++LSMDN+R+LDLDSIIAEV+AQYEEIA +SK EAE LY +K Sbjct: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376 Query: 322 ----------------------------------------CADLETAIADAEQRGDCALK 341 C +++ AIADAEQRG+ ALK Sbjct: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436 Query: 342 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 401 DAR KL++LE AL QAKE+LAR+LR+YQEL+++KLALD+EIATYRKLLE EECRMSG+ Sbjct: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496 Query: 402 NSVSISVISSTNA----------GAGGAGFSMGFGASS-SYSYKTAAADVKTKGSCG 447 ++V++SV SST + G+GG G S G G SS S SY + ++G G Sbjct: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG 553 Score = 32.7 bits (73), Expect = 0.73 Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 3/75 (4%) Query: 11 GERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGR 70 G R G G ++ GG GS S G GSK S GG + GG R Sbjct: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGG---GSKGGSISGGGYGSGGGKHSSGGGSR 603 Query: 71 LGGFVGTAFGSAGLG 85 G G +GS G G Sbjct: 604 GGSSSGGGYGSGGGG 618 Score = 29.3 bits (64), Expect = 8.0 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 5/63 (7%) Query: 24 SGGIGSSSASFRARVKGSASFGS---KSLSCLGGSRSLALSAAARRGGGRLGGFVGTAFG 80 SGG GSSS GS+S+GS +S S G ++S GG GG G+ G Sbjct: 521 SGGRGSSSGG--GYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578 Query: 81 SAG 83 S G Sbjct: 579 SKG 581 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 446 bits (1146), Expect = e-125 Identities = 260/523 (49%), Positives = 331/523 (63%), Gaps = 104/523 (19%) Query: 16 FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRL---- 71 FS C GG GS A FGS+SL LGGS+S+++S A RGGGR Sbjct: 46 FSSCG----GGGGSFGAG--------GGFGSRSLVNLGGSKSISISVA--RGGGRGSGFG 91 Query: 72 -----------------------------------GGFVGTAFGSAGLGPKCPSVCPPGG 96 GGF G FG G G VCPPGG Sbjct: 92 GGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151 Query: 97 IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETK 156 I +VT+N+SLL PLNVE+DPEIQ+V+++EREQIK+LNN+FASFIDKVRFLEQQNQVL+TK Sbjct: 152 IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTK 211 Query: 157 WNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216 W LLQQ+D + NLEP +E +I+NL+++++ L D RLDSEL+NMQD+VEDY+ +YE Sbjct: 212 WELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYE 271 Query: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276 EIN+RT AENEFV +KKDVD AYM KV+LQAK+D+L EI F LY+ E++Q+Q+ IS Sbjct: 272 DEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS 331 Query: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK--------------- 321 +T+++LSMDNNR LDLDSIIAEV+AQYE+IA KSKAEAE+LYQ+K Sbjct: 332 ETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSV 391 Query: 322 ---------------------------CADLETAIADAEQRGDCALKDARAKLDELEGAL 354 ++L+ +I+DAEQRG+ ALKDA+ KL++LE AL Sbjct: 392 RNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDAL 451 Query: 355 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISS--- 411 QAKE+LAR+LR+YQEL++ KLALD+EIATYR LLE EE RMSGE +VS+SV +S Sbjct: 452 QQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTT 511 Query: 412 ----TNAGAGGAGFSMGFGA--SSSYSYKTAAADVKTKGSCGS 448 + G GG G+ G + S SY + +GS GS Sbjct: 512 ISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGS 554 >gi|194018511 keratin 77 [Homo sapiens] Length = 578 Score = 427 bits (1099), Expect = e-120 Identities = 259/551 (47%), Positives = 341/551 (61%), Gaps = 89/551 (16%) Query: 8 FPRGERLGFSGCSAVLSGGIGSSSASF---RARVKGSA------SFGSKSLSCLGGSRSL 58 F R +S S+ SGG + S R R G FGS+SL LGGSRS+ Sbjct: 11 FSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSI 70 Query: 59 ALSAAARR-------------GGGR--------LGGFVGTAFGSAGLGPKCPSV------ 91 +++ R GGGR GGF G FG AG G + Sbjct: 71 SINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPY 130 Query: 92 CPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 151 CPPGGI +VT+N+SLL PL++E+DPEIQR++ QEREQI LNNKFASFIDKVRFLEQQNQ Sbjct: 131 CPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQ 190 Query: 152 VLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDY 211 VL+TKW LLQQ++ + NLEP+ E YI +L++Q+++LS + +R ++E+R+MQD+VEDY Sbjct: 191 VLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDY 250 Query: 212 KKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQI 271 K +YE EIN+RT +EN+FVVLKKDVDAAY++KV+L+++VD+LT E+ F K L+ E++Q+ Sbjct: 251 KSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQV 310 Query: 272 QSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLE----- 326 Q+HISDT+++LSMDNNR LDLDSII VR QYE IA +SK EAE LYQTK +L+ Sbjct: 311 QTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGR 370 Query: 327 -------------------------------------TAIADAEQRGDCALKDARAKLDE 349 + I+DAE+RG+ AL+DA KL + Sbjct: 371 HGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQD 430 Query: 350 LEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI 409 LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LLE EE RMSGE + VSISV Sbjct: 431 LEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQ 490 Query: 410 S---STNAGAGGAGF--SMGFGASS------SYSYKTAAADVKTKGSCGSELKDPLAKTS 458 + S N GAGG G S G+G S SY+ A ++ G GS Sbjct: 491 NSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYG 550 Query: 459 GSSCATKKASR 469 GS + + +SR Sbjct: 551 GSGRSGRGSSR 561 >gi|89357932 keratin 5b [Homo sapiens] Length = 520 Score = 397 bits (1021), Expect = e-111 Identities = 241/509 (47%), Positives = 310/509 (60%), Gaps = 74/509 (14%) Query: 15 GFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLS----CLGGSRSLALSAAARRGGGR 70 GFS SA + G S F +R F S+SL+ CL GSR + GGR Sbjct: 11 GFSARSACSARSRGRSRGGFSSR----GGFSSRSLNSFGGCLEGSRGSTWGS-----GGR 61 Query: 71 LGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIK 130 LG G G GL S+CPPGGI +VT+N++LL PL +E+DP+ Q VR QE ++I+ Sbjct: 62 LGVRFGEWSGGPGL-----SLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIR 116 Query: 131 ALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEML 190 LNN+FASFIDKVRFLEQQN+VLETKW+LLQQ L+ ++ LEP++E + L+KQLE L Sbjct: 117 TLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQL 176 Query: 191 SGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKV 250 G+ LD+EL+ +D E+YK +YE E +RR EN+FVVLKKDVD +++K+EL+ K+ Sbjct: 177 QGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKL 236 Query: 251 DSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKS 310 ++L + + F K L E E+ Q+Q+ SDTS+VLSMDNNR LD SII EVRA+YEEIA S Sbjct: 237 EALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSS 296 Query: 311 KAEAETLYQTKC------------------------------------------ADLETA 328 KAEAE LYQTK A L+ A Sbjct: 297 KAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAA 356 Query: 329 IADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKL 388 I DAEQRG+ ALKDA+AK+DELE AL AK+ LAR+L EYQEL S KL+LD+EIATYR+L Sbjct: 357 ITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRL 416 Query: 389 LESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFG---ASSSYSYKTAAADVKTKGS 445 LE EECRMSGE + V+IS + + +GG G +G S S + + T GS Sbjct: 417 LEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGS 476 Query: 446 ---CGSELKDPL-------AKTSGSSCAT 464 GS KDP+ ++GSSC T Sbjct: 477 NIILGSG-KDPVLDSCSVSGSSAGSSCHT 504 >gi|4504919 keratin 8 [Homo sapiens] Length = 483 Score = 397 bits (1020), Expect = e-110 Identities = 229/456 (50%), Positives = 300/456 (65%), Gaps = 58/456 (12%) Query: 33 SFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRLGGFVGTAFGSAGLGPKCPSVC 92 S++ G +F S+S + GSR ++ S+ +R G G +G +G A Sbjct: 9 SYKVSTSGPRAFSSRSYTSGPGSR-ISSSSFSRVGSSNFRGGLGGGYGGAS--------- 58 Query: 93 PPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQV 152 GGI VTVN+SLL+PL +E+DP IQ VR QE+EQIK LNNKFASFIDKVRFLEQQN++ Sbjct: 59 GMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKM 118 Query: 153 LETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYK 212 LETKW+LLQQ R N++ ++E YI+NL++QLE L + ++L++EL NMQ LVED+K Sbjct: 119 LETKWSLLQQQ--KTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFK 176 Query: 213 KRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQ 272 +YE EIN+RT ENEFV++KKDVD AYMNKVEL+++++ LTDEI F + LYE EI ++Q Sbjct: 177 NKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQ 236 Query: 273 SHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKC---------- 322 S ISDTS+VLSMDN+R LD+DSIIAEV+AQYE+IA +S+AEAE++YQ K Sbjct: 237 SQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKH 296 Query: 323 --------------------------------ADLETAIADAEQRGDCALKDARAKLDEL 350 A LE AIADAEQRG+ A+KDA AKL EL Sbjct: 297 GDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSEL 356 Query: 351 EGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS 410 E AL +AK+++AR LREYQEL+++KLALD+EIATYRKLLE EE R+ N +S+ + Sbjct: 357 EAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQN---MSIHT 413 Query: 411 STNAG-AGGAGFSMGFGASSSYSYKTAAADVKTKGS 445 T +G AGG + G S SY ++ GS Sbjct: 414 KTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGS 449 >gi|67782365 keratin 7 [Homo sapiens] Length = 469 Score = 396 bits (1018), Expect = e-110 Identities = 234/439 (53%), Positives = 293/439 (66%), Gaps = 59/439 (13%) Query: 55 SRSLALS---AAARRGGGRLGGFVGTAFGSAGLGPKCPSVC-------PPG-GIPQVTVN 103 SRS A S A R R GG ++ GLG P V P G GI +VT+N Sbjct: 12 SRSAAFSGRGAQVRLSSARPGGLGSSSL--YGLGASRPRVAVRSAYGGPVGAGIREVTIN 69 Query: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163 +SLLAPL ++ DP +QRVR +E EQIK LNNKFASFIDKVRFLEQQN++LETKW LLQ+ Sbjct: 70 QSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQ 129 Query: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223 + L I+E I+ L+ QLE L DG RL++ELR+MQD+VED+K +YE EIN RT Sbjct: 130 KSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRT 188 Query: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283 AAENEFVVLKKDVDAAYM+KVEL+AKVD+L DEI F + L E E+T++QS ISDTS+VLS Sbjct: 189 AAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLS 248 Query: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKC--------------------- 322 MDN+R LDLD IIAEV+AQYEE+A S+AEAE YQTK Sbjct: 249 MDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEI 308 Query: 323 ---------------------ADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEEL 361 A LE AIA+AE+RG+ ALKDARAK +ELE AL + K+++ Sbjct: 309 SEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDM 368 Query: 362 ARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF 421 AR LREYQEL+S+KLALD+EIATYRKLLE EE R++G+ +V+ISV++ST + G G Sbjct: 369 ARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGI 428 Query: 422 SMGFG---ASSSYSYKTAA 437 + G S++ S+ ++A Sbjct: 429 GLTLGGTMGSNALSFSSSA 447 >gi|15431316 keratin, hair, basic, 4 [Homo sapiens] Length = 600 Score = 367 bits (941), Expect = e-101 Identities = 235/528 (44%), Positives = 302/528 (57%), Gaps = 92/528 (17%) Query: 11 GERLG-FSGCSAVLSGGIG-----SSSASFRARVKGSASFGSKSLSCLGG--SRSLALSA 62 G R+G FS CSA+ + S S +G SFGS+S+ G R A+ + Sbjct: 11 GHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGS 70 Query: 63 AARRGGGRLGGFVGTAFGSA---GLGPKCPSVCPPG-----------------------G 96 G R G G FG GLGP+ S G G Sbjct: 71 RPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVG 130 Query: 97 IPQ------VTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQN 150 +P VTVNKSLL PLN+E+DP QRV+ E+EQIK LNNKFASFIDKVRFLEQQN Sbjct: 131 VPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQN 190 Query: 151 QVLETKWNLLQQLDLNNC-RKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVE 209 ++LETKW+ LQ+ C R NLEP++E YI+NL++QLE+L D RL +E ++QD++E Sbjct: 191 KLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLE 247 Query: 210 DYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEIT 269 +KK+YE E+ R AENEFV LKKDVDAA+MNK +L+A VD+LT EI F K LY EI Sbjct: 248 GFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQ 307 Query: 270 QIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKC------- 322 +QSHIS+TS+++ MDN+RDL+LD IIAEV+AQYEE+A +S+A+AE YQTK Sbjct: 308 LLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTA 367 Query: 323 -----------------------------------ADLETAIADAEQRGDCALKDARAKL 347 A LE A+A+AEQ+G+ L DA+ KL Sbjct: 368 GQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKL 427 Query: 348 DELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSIS 407 +LE AL QAK+++AR L EYQEL++ KL LD+EIATYR+LLE EE R+ E V+IS Sbjct: 428 ADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNIS 486 Query: 408 VISSTNAGAGG-----AGFSMGFGASSSYSYKTAAADVKTKGSCGSEL 450 V SS G AG ++ G + + A SCG L Sbjct: 487 VSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSL 534 >gi|4504935 keratin 85 [Homo sapiens] Length = 507 Score = 349 bits (896), Expect = 3e-96 Identities = 209/461 (45%), Positives = 286/461 (62%), Gaps = 62/461 (13%) Query: 11 GERLGFSGCSAVL---SGGIGSSSASFR--ARVKGSASFGSKSLSCLGGSRSLALSAAAR 65 G FS CSAV S+A +R + +G FGS+SL LG S R Sbjct: 13 GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLG-------SCGPR 65 Query: 66 RG-GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQ 124 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ + Sbjct: 66 IAVGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQE 122 Query: 125 EREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQ 184 E+EQIK+LN++FA+FIDKVRFLEQQN++LETKW Q + C NLEP++ GYI L+ Sbjct: 123 EKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPLFSGYIETLR 180 Query: 185 KQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKV 244 ++ E + D RL SEL ++Q+++E YKK+YE E+ R AENEFVVLKKDVD AY+ K Sbjct: 181 REAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKS 240 Query: 245 ELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYE 304 +L+A V++L +E F + LYE EI +Q+HISDTS+++ MDN+RDL++D IIAE++AQY+ Sbjct: 241 DLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYD 300 Query: 305 EIALKSKAEAETLYQTKC------------------------------------------ 322 ++A +S+AEAE+ Y++KC Sbjct: 301 DVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQR 360 Query: 323 ADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEI 382 A LE A+A+AEQ+G+ AL DAR KL ELEGAL +AK+++A +L+EYQE+++ KL LD+EI Sbjct: 361 AKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEI 420 Query: 383 ATYRKLLESEECRMSGEYPNSVSISVISST-NAGAGGAGFS 422 ATYR+LLE EE R+ E SV++ V SS GG +S Sbjct: 421 ATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYS 460 >gi|27477127 keratin 82 [Homo sapiens] Length = 513 Score = 345 bits (886), Expect = 4e-95 Identities = 226/522 (43%), Positives = 303/522 (58%), Gaps = 78/522 (14%) Query: 8 FPRGERLG---FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLA----- 59 F G R G FS SAV+ + + S + + G ++L CLG SRSL Sbjct: 6 FQPGSRCGSQSFSSYSAVMPRMVTHYAVS-KGPCRPGGGRGLRALGCLG-SRSLCNVGFG 63 Query: 60 LSAAARRGGGRLGGFVGTAFGSAGLGPKC-PSVCPPGGIPQVTVNKSLLAPLNVEMDPEI 118 A R GG L GF LG C PS C I VT+N+SLL PL +E+DP + Sbjct: 64 RPRVASRCGGTLPGF------GYRLGATCGPSAC----ITPVTINESLLVPLALEIDPTV 113 Query: 119 QRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEG 178 QRV+ E+EQIK LNN+FASFI+KVRFLEQ+N++LETKWN +QQ C+ N+EPI+EG Sbjct: 114 QRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPIFEG 171 Query: 179 YISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDA 238 YIS L++QL+ +SGD VRL+SEL ++Q +E YKK+YE E++ R ENEFV LKKDVD Sbjct: 172 YISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDT 231 Query: 239 AYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAE 298 A++ K +L+ ++L EI F K LYE EI +QS IS+TS+++ MDN+R+LD+D IIAE Sbjct: 232 AFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAE 291 Query: 299 VRAQYEEIALKSKAEAETLYQTKCAD---------------------------------- 324 ++AQY++IA +SKAEAE YQ + + Sbjct: 292 IKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETE 351 Query: 325 --------LETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKL 376 LE AIA+AEQ+G+ AL DA+ KL LE AL +AK+++A +L+EYQE+++ KL Sbjct: 352 NVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKL 411 Query: 377 ALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA------GAGGAGFSMGF----G 426 LD+EIATYR+LLE EE R+ E V+ISV SS A G S G G Sbjct: 412 GLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNG 470 Query: 427 ASSSYSYKTAAADVKTKG--SCGSELKDPLAKTSGSSCATKK 466 S + +G SCGS K + +G S + K Sbjct: 471 GCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512 >gi|169790853 keratin, hair, basic, 1 [Homo sapiens] Length = 505 Score = 336 bits (861), Expect = 3e-92 Identities = 196/430 (45%), Positives = 274/430 (63%), Gaps = 63/430 (14%) Query: 42 ASFGSKSLSCLG--GSRS--LALSAAARRG----GGRLGGFV------GTAFGSAG--LG 85 + FG ++ SC+ G R ++AA RG G GGF G GS G G Sbjct: 5 SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFG 64 Query: 86 PKCPSVCPPGG--IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143 + VC P I V+VN+SLL PLN+E+DP Q V+ +E+EQIK+LN++FA+FIDKV Sbjct: 65 YRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 124 Query: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203 RFLEQQN++LETK Q + C+ NLEP++EGYI L+++ E + D RL SEL + Sbjct: 125 RFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREAECVEADSGRLASELNH 182 Query: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263 +Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+A V++L EI F + L Sbjct: 183 VQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 242 Query: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCA 323 YE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I +S+AEAE+ Y++KC Sbjct: 243 YEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCE 302 Query: 324 D------------------------------------------LETAIADAEQRGDCALK 341 + LE A+A +EQ+G+ AL Sbjct: 303 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 362 Query: 342 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 401 DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATYR+LLE EE R+ E Sbjct: 363 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGI 421 Query: 402 NSVSISVISS 411 +V++ V SS Sbjct: 422 GAVNVCVSSS 431 >gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sapiens] Length = 486 Score = 335 bits (859), Expect = 5e-92 Identities = 185/386 (47%), Positives = 256/386 (66%), Gaps = 48/386 (12%) Query: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 52 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108 Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++EGYI L+++ Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166 Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 E + D RL SEL ++Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+ Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226 Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286 Query: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325 +S+AEAE+ Y++KC + L Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346 Query: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406 Query: 386 RKLLESEECRMSGEYPNSVSISVISS 411 R+LLE EE R+ E SV++ V SS Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431 >gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 486 Score = 335 bits (859), Expect = 5e-92 Identities = 185/386 (47%), Positives = 256/386 (66%), Gaps = 48/386 (12%) Query: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 52 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108 Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++EGYI L+++ Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166 Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 E + D RL SEL ++Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+ Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226 Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286 Query: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325 +S+AEAE+ Y++KC + L Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346 Query: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406 Query: 386 RKLLESEECRMSGEYPNSVSISVISS 411 R+LLE EE R+ E SV++ V SS Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431 >gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sapiens] Length = 486 Score = 335 bits (859), Expect = 5e-92 Identities = 185/386 (47%), Positives = 256/386 (66%), Gaps = 48/386 (12%) Query: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 52 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108 Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++EGYI L+++ Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166 Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 E + D RL SEL ++Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+ Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226 Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286 Query: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325 +S+AEAE+ Y++KC + L Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346 Query: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406 Query: 386 RKLLESEECRMSGEYPNSVSISVISS 411 R+LLE EE R+ E SV++ V SS Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431 >gi|14318422 keratin 86 [Homo sapiens] Length = 486 Score = 335 bits (859), Expect = 5e-92 Identities = 185/386 (47%), Positives = 256/386 (66%), Gaps = 48/386 (12%) Query: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 52 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108 Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++EGYI L+++ Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166 Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 E + D RL SEL ++Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+ Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226 Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286 Query: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325 +S+AEAE+ Y++KC + L Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346 Query: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406 Query: 386 RKLLESEECRMSGEYPNSVSISVISS 411 R+LLE EE R+ E SV++ V SS Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431 >gi|169790841 keratin 83 [Homo sapiens] Length = 493 Score = 331 bits (849), Expect = 8e-91 Identities = 183/386 (47%), Positives = 255/386 (66%), Gaps = 48/386 (12%) Query: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 57 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113 Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++ GYI L+++ Sbjct: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171 Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 E + D RL SEL ++Q+++E YKK+YE E+ R AENEFV LKKDVD AY+ K +L+ Sbjct: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231 Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA Sbjct: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291 Query: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325 +S+AEAE+ Y++KC + L Sbjct: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351 Query: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411 Query: 386 RKLLESEECRMSGEYPNSVSISVISS 411 R+LLE EE R+ E +V++ V SS Sbjct: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.357 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,667,194 Number of Sequences: 37866 Number of extensions: 668773 Number of successful extensions: 4588 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 155 Number of HSP's successfully gapped in prelim test: 331 Number of HSP's that attempted gapping in prelim test: 3364 Number of HSP's gapped (non-prelim): 1205 length of query: 469 length of database: 18,247,518 effective HSP length: 106 effective length of query: 363 effective length of database: 14,233,722 effective search space: 5166841086 effective search space used: 5166841086 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.