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Search of human proteins with 223972704
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
(922 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 1865 0.0
gi|23503301 hypothetical protein LOC196472 [Homo sapiens] 97 5e-20
gi|89363024 hypothetical protein LOC161142 [Homo sapiens] 93 1e-18
gi|222418633 family with sequence similarity 71, member B [Homo ... 92 2e-18
gi|76253859 hypothetical protein LOC112703 [Homo sapiens] 92 2e-18
gi|23957696 hypothetical protein LOC149647 [Homo sapiens] 92 2e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni... 82 2e-15
gi|110349719 titin isoform N2-A [Homo sapiens] 78 3e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 3e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 74 5e-13
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 74 5e-13
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 74 5e-13
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 74 5e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 74 8e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 73 1e-12
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 72 2e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 5e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 68 4e-11
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 68 4e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens] 67 6e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 6e-11
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 67 8e-11
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 67 8e-11
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 67 8e-11
gi|19924099 synapsin I isoform Ia [Homo sapiens] 66 1e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 66 1e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 66 1e-10
gi|19924097 synapsin I isoform Ib [Homo sapiens] 66 2e-10
gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapi... 66 2e-10
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 65 2e-10
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 1865 bits (4832), Expect = 0.0
Identities = 922/922 (100%), Positives = 922/922 (100%)
Query: 1 MIWLRNRRCLEPLQGTPKWVPVLGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFV 60
MIWLRNRRCLEPLQGTPKWVPVLGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFV
Sbjct: 1 MIWLRNRRCLEPLQGTPKWVPVLGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFV 60
Query: 61 NHRTNRLAMGVAASLPGLVLPDILLIGQPAEDRDCSGLVLTRMIPLDLVHLCVHDLSAWR 120
NHRTNRLAMGVAASLPGLVLPDILLIGQPAEDRDCSGLVLTRMIPLDLVHLCVHDLSAWR
Sbjct: 61 NHRTNRLAMGVAASLPGLVLPDILLIGQPAEDRDCSGLVLTRMIPLDLVHLCVHDLSAWR 120
Query: 121 LKLRLVSGRQYYLALDAPDNEVGFLFHCWVRLINLLQEPAPTWTPRTTRTAPLDMPLAEA 180
LKLRLVSGRQYYLALDAPDNEVGFLFHCWVRLINLLQEPAPTWTPRTTRTAPLDMPLAEA
Sbjct: 121 LKLRLVSGRQYYLALDAPDNEVGFLFHCWVRLINLLQEPAPTWTPRTTRTAPLDMPLAEA 180
Query: 181 PASTWHLQDQPISRHAVRVAERNFPHKTVAAQRQRKAKALKRSFKSQAVGDSVPLIWSQL 240
PASTWHLQDQPISRHAVRVAERNFPHKTVAAQRQRKAKALKRSFKSQAVGDSVPLIWSQL
Sbjct: 181 PASTWHLQDQPISRHAVRVAERNFPHKTVAAQRQRKAKALKRSFKSQAVGDSVPLIWSQL 240
Query: 241 EHADVRKKPAEKKSHSDPRPDRTHTQIRLPEKTSITTWTIFSIISSTANQTQSSPKACTS 300
EHADVRKKPAEKKSHSDPRPDRTHTQIRLPEKTSITTWTIFSIISSTANQTQSSPKACTS
Sbjct: 241 EHADVRKKPAEKKSHSDPRPDRTHTQIRLPEKTSITTWTIFSIISSTANQTQSSPKACTS 300
Query: 301 ASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTEDLMDSGGSTLSSAAS 360
ASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTEDLMDSGGSTLSSAAS
Sbjct: 301 ASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTEDLMDSGGSTLSSAAS 360
Query: 361 GLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQ 420
GLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQ
Sbjct: 361 GLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQ 420
Query: 421 KLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSR 480
KLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSR
Sbjct: 421 KLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSR 480
Query: 481 KASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKAL 540
KASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKAL
Sbjct: 481 KASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKAL 540
Query: 541 PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVV 600
PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVV
Sbjct: 541 PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVV 600
Query: 601 EMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPG 660
EMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPG
Sbjct: 601 EMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPG 660
Query: 661 VRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLP 720
VRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLP
Sbjct: 661 VRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLP 720
Query: 721 SWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPW 780
SWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPW
Sbjct: 721 SWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPW 780
Query: 781 GEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKM 840
GEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKM
Sbjct: 781 GEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKM 840
Query: 841 EATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLELETVRNTATKAEEIQEES 900
EATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLELETVRNTATKAEEIQEES
Sbjct: 841 EATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLELETVRNTATKAEEIQEES 900
Query: 901 GVLNLLPSLQHSQHSEWPDAGA 922
GVLNLLPSLQHSQHSEWPDAGA
Sbjct: 901 GVLNLLPSLQHSQHSEWPDAGA 922
>gi|23503301 hypothetical protein LOC196472 [Homo sapiens]
Length = 241
Score = 97.4 bits (241), Expect = 5e-20
Identities = 53/157 (33%), Positives = 86/157 (54%), Gaps = 15/157 (9%)
Query: 23 LGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPD 82
+G+LQ+ L KGEY R PMFES+F+Q++ +G + V++R + MG+ + P L LPD
Sbjct: 25 MGKLQRQLYKGEYTIFRYAPMFESDFIQISKRGEVIDVHNRARMVTMGIVRTSPCLTLPD 84
Query: 83 ILLIGQPA---------------EDRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLVS 127
++L+ +PA E L LTR++PL V + +H+ +L L+L +
Sbjct: 85 VMLLARPAAVCDNARCGPATQKRESPPAEILELTRLLPLMFVKITIHNSVKKQLHLKLAT 144
Query: 128 GRQYYLALDAPDNEVGFLFHCWVRLINLLQEPAPTWT 164
GR +YL L P + LF W L+ +L+ P ++
Sbjct: 145 GRSFYLQLCPPSDASEDLFVHWENLVYILRPPVEAYS 181
>gi|89363024 hypothetical protein LOC161142 [Homo sapiens]
Length = 422
Score = 92.8 bits (229), Expect = 1e-18
Identities = 55/149 (36%), Positives = 78/149 (52%), Gaps = 15/149 (10%)
Query: 25 ELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPDIL 84
+LQ L GEY P PM ESNF+QV +G +++++R N + +G+ S +P+++
Sbjct: 28 DLQNMLDGGEYAPFVSPPMLESNFIQVNRRGESIYLHNRANWVTVGICFSSSTHKIPNVM 87
Query: 85 LIGQ--PAEDRD-------------CSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLVSGR 129
L+ P +D LVLTR +PL V L VHD LK++LVSGR
Sbjct: 88 LLAHLTPGAQKDTETLFKSLLTSPPAEKLVLTRFLPLQFVTLSVHDAENMSLKVKLVSGR 147
Query: 130 QYYLALDAPDNEVGFLFHCWVRLINLLQE 158
YYL L + LF WV LI+LL +
Sbjct: 148 AYYLQLCTSAYKQDTLFSQWVALISLLNQ 176
>gi|222418633 family with sequence similarity 71, member B [Homo
sapiens]
Length = 605
Score = 92.0 bits (227), Expect = 2e-18
Identities = 52/163 (31%), Positives = 87/163 (53%), Gaps = 17/163 (10%)
Query: 23 LGELQKTL-QKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLP 81
+G+LQ+ L +GEY + PMFESNF+Q+ +G + V++R + +G+ + P L LP
Sbjct: 25 MGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLP 84
Query: 82 DILLIGQPAE----------------DRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRL 125
D++++ QP + R L LTR++PL V + +HD +L+L+L
Sbjct: 85 DVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKL 144
Query: 126 VSGRQYYLALDAPDNEVGFLFHCWVRLINLLQEPAPTWTPRTT 168
+GR +YL L + LF W +L+ LL+ P ++ T
Sbjct: 145 ATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVESYCSTPT 187
>gi|76253859 hypothetical protein LOC112703 [Homo sapiens]
Length = 231
Score = 92.0 bits (227), Expect = 2e-18
Identities = 60/142 (42%), Positives = 79/142 (55%), Gaps = 8/142 (5%)
Query: 26 LQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPDILL 85
LQ+ LQ GE+ R P+FESNFVQVT G N + MGVAAS P L LPD+LL
Sbjct: 96 LQRYLQSGEFDQFRDFPIFESNFVQVTRLG------EVANEVTMGVAASSPALELPDLLL 149
Query: 86 IGQPAEDRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLVSGRQYYLALDAPDNEVGFL 145
+ PA++ L L + PL V L VHD S +L+++L + R +YL L AP
Sbjct: 150 LAGPAKEN--GHLQLFGLFPLKFVQLFVHDKSRCQLEVKLNTSRTFYLQLRAPLKTRDRE 207
Query: 146 FHCWVRLINLLQEPAPTWTPRT 167
F WVRL+ L+ + + P T
Sbjct: 208 FGQWVRLLYRLRFLSASAVPFT 229
>gi|23957696 hypothetical protein LOC149647 [Homo sapiens]
Length = 594
Score = 92.0 bits (227), Expect = 2e-18
Identities = 56/157 (35%), Positives = 87/157 (55%), Gaps = 24/157 (15%)
Query: 23 LGELQKTLQKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPD 82
+G+LQ+ L KGEY + P+FES+F+Q+T +G + V++R + MG+A + P L LPD
Sbjct: 25 MGKLQRQLYKGEYDIFKYAPIFESDFIQITKRGEVIDVHNRVRMVTMGIARTSPILPLPD 84
Query: 83 ILLIGQPA----------------EDRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLV 126
++L+ +PA + + L LTR++PL V + V D +L+L+
Sbjct: 85 VMLLARPATGCEEYAGHGQATKRKKRKAAKNLELTRLLPLRFVRISVQDHEKQQLRLKFA 144
Query: 127 SGRQYYL----ALDAPDNEVGFLFHCWVRLINLLQEP 159
+GR YL ALD D+ LF W +LI LL+ P
Sbjct: 145 TGRSCYLQLCPALDTRDD----LFAYWEKLIYLLRPP 177
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 82.4 bits (202), Expect = 2e-15
Identities = 147/548 (26%), Positives = 204/548 (37%), Gaps = 119/548 (21%)
Query: 352 GSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCK 411
G +S G AP PPAA TP S P+G P +G PP PS T
Sbjct: 1299 GGPATSPPKG-APTPPAA---TPPS--PKGSPGTPP---PKGAPTPPAVTPPSPKGTP-T 1348
Query: 412 APFLVDQSQKLPAVPASSWKP-PPGLAPPQKAPAASAP--PRKAPAVPAP--SQKAPAV- 465
P S+ P P+S P PP P K A P P++ PA+P+P +PAV
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 466 PAPSQKAPAIPAPSRKASAAS-----------ASPRKASAVPAPPQKTPPPSQKAPSVPT 514
P +KAPA P A+ S S +KA A AP PS K PT
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD--PT 1466
Query: 515 IPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGR 574
+P AV+P +PK+ PAP Q A +SP + A P LP P +P
Sbjct: 1467 LP--AVTPPSPKEP----PAPKQVATSSSPKK-APATPAPMGAPTLPAVIPSSPKEVPAT 1519
Query: 575 AVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSP------------------ESPFTVT 616
R P T+ +++T +A P E+P T +
Sbjct: 1520 PSSRRDPIA----PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575
Query: 617 KKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVKAK 676
KE+ S VT ++G ++ + SP KE
Sbjct: 1576 SKEA-----SSPPAVTPSTYKGAPSPKELLIPPAVTSPSP-------KEAPTPP------ 1617
Query: 677 ELAVEGPSQEHSRPFSVEALTLTKLMITANS-KEQPSKSALVSLPSWLLATPQASATSMM 735
AV PS E T T +T +S K+ P+ A V+ PQAS
Sbjct: 1618 --AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG-ATVPQAS----- 1669
Query: 736 ASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEPPWDP----- 790
+P++ G +L K V+V PES + R + K+ PP P
Sbjct: 1670 KGLPAKKGPTAL---KEVLVAPAPESTPIITAPTRKGPQTKK---SSATSPPICPDPSAK 1723
Query: 791 ---KGP-------PKVPFRSKPTSASLKREGISQAP------------IPLTASPWEDLR 828
KGP P +P + K +S + K + S +P PLTA+ +E +
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQ-KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782
Query: 829 PSPLSETL 836
P P S ++
Sbjct: 1783 PKPESASV 1790
Score = 80.1 bits (196), Expect = 9e-15
Identities = 158/587 (26%), Positives = 225/587 (38%), Gaps = 130/587 (22%)
Query: 351 GGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSC 410
GG T S+ G P PPAA S K GP + P P +P G TS
Sbjct: 1358 GGPTTPSSKEG--PTPPAATPS----------HKGGPAMTPPSPKRGPAIPSPKGDPTS- 1404
Query: 411 KAPFLVDQS-QKLPAVPAS---SWKPPPG-LAPP-------QKAPAASAPPRKAPAVPAP 458
P ++ S +K PA P + + P G L PP +KAPA SAP + PA P+
Sbjct: 1405 --PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP-KGGPATPS- 1460
Query: 459 SQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAP------PQKTPPPSQKAPSV 512
S+ P +PA + +P P P+ K A S+SP+KA A PAP P P ++ P+
Sbjct: 1461 SKGDPTLPAVTPPSPKEP-PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPAT 1519
Query: 513 PTIPQKAVSPTAP-----------KKKSLLLPA---PSQKALPTSPTEYQMALSPPASRG 558
P+ + ++PTA K++L+ PA PS K P PT + +P +
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579
Query: 559 KLPGDFDVLPTGIPGR----------AVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKS 608
P V P+ G AV S P VT + E + +
Sbjct: 1580 SSPPA--VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG-T 1636
Query: 609 PESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQ 668
P SP VT KD S T ++ G A + + S LP
Sbjct: 1637 PTSP-PVTPSSLKD---SPTSPASVTCKMG----------ATVPQASKGLPA-------- 1674
Query: 669 RKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPS--KSALVSLPSWLLAT 726
+K KE+ V P+ E S P +ITA +++ P KS+ S P
Sbjct: 1675 KKGPTALKEVLV-APAPE-STP-----------IITAPTRKGPQTKKSSATSPP----IC 1717
Query: 727 PQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEP 786
P SA + G LS + P++ ++ S T +GK + P G + P
Sbjct: 1718 PDPSAKN------GSKGPLSTVAPAPLLPVQKDSSKT--AKGK----DASHSPKGPLAPP 1765
Query: 787 PWDPKGP-PKVPFRS---KPTSASLKREGISQAPIPLTASPWEDLRPS----PLSETLI- 837
P F KP SAS+ +PL SP L P P S L+
Sbjct: 1766 ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVL 1825
Query: 838 ---SKMEATARASQQPKRVSQEPMR--MPAQHPLATVGSSSEILLPM 879
SK A A + + EP+ +P Q L + + +P+
Sbjct: 1826 ESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPV 1872
Score = 79.3 bits (194), Expect = 1e-14
Identities = 149/603 (24%), Positives = 205/603 (33%), Gaps = 108/603 (17%)
Query: 353 STLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKA 412
+T S GLA PP +TP ++ P P G P P P+ S K
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPP------SPKGGLATPSPKGAPTTPAATPPSPKG 1207
Query: 413 PFLVDQSQKLPAVPASSWKPP---------------PGLAPPQ-KAPAASAPPRKAPAVP 456
+ P PA++ P P PP K A+ PP+ AP P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 457 A---PSQKAPAVPAPSQKAP---AIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAP 510
A PS K P + AP + PS K A++ P+ A P PP TPP + +P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA---PTPPAATPPSPKGSP 1324
Query: 511 SVPTIPQK------AVSPTAPK-KKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGD 563
P P K AV+P +PK +L PS K PT+P+ + +PPA+ G
Sbjct: 1325 GTP--PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE-GPTPPAATPSHKGG 1381
Query: 564 FDVLPTGIPGRAVLERSQSGGKPEP-VVTVRTQETDVVEMT-----TQAKSPESPFTVTK 617
+ P P R S G P V+ + ++ +T T +K +P VT
Sbjct: 1382 PAMTPPS-PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP 1440
Query: 618 KESK-----------DILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKEL 666
K S + TL A E A SP +
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
Query: 667 EQRKRWVKAKELAVEGPSQEHSR--PFSVEALTLTK-----------LMITANSKEQPSK 713
E P+ SR P + A L+K L+ A + P K
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 714 SALVSLPSWLLATPQA-SATSMMASVPS----RPGQLSLLEGKPVVVREQPESHTWVKEG 768
+ + P ATP + A+S A PS P LL P V P
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI-PPAVTSPSP--------- 1610
Query: 769 KRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLR 828
KE P PP KGP + PTS P+T S +D
Sbjct: 1611 -------KEAPTPPAVTPPSPEKGPATPAPKGTPTSP------------PVTPSSLKDSP 1651
Query: 829 PSPLSETLISKMEATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLELETVRN 888
SP S T KM AT + + + P + S+ I P +T ++
Sbjct: 1652 TSPASVT--CKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
Query: 889 TAT 891
+AT
Sbjct: 1710 SAT 1712
Score = 76.6 bits (187), Expect = 1e-13
Identities = 146/588 (24%), Positives = 195/588 (33%), Gaps = 91/588 (15%)
Query: 352 GSTLSSAASGLAPYPPAACLSTPYSS----------IPRGREKAGPMGSHQGPGPPPCQK 401
GS ++ AP PAA L +P P P G P P
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM 1104
Query: 402 APSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPA---P 458
P+ S K + P PA++ P K A+ PP+ AP PA P
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAAT-------PPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 459 SQKAPAVPAPSQKAPAIPA---PSRKASAASASPRKASAVPAPPQKTPP--------PSQ 507
S K P + AP PA PS K A+ SP+ A P P TPP PS
Sbjct: 1158 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA---PTTPAATPPSPKGGLATPSP 1214
Query: 508 KAPSVPTIPQKAVSPTAPK--------KKSLLLPA---PSQKALPTSPTEYQMALSPPAS 556
K PT P A +P +PK K + PA PS K P +P P A+
Sbjct: 1215 K--GAPTTP--AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 557 RGKLPGDFDVLP-TGIPGRAVLERSQSGGKP----------EPVVTVRTQETDVVEMTTQ 605
L G P G P AV+ G P P T + + T
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS--PGTPP 1328
Query: 606 AKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKE 665
K +P VT K + T T + +G +P G +
Sbjct: 1329 PKGAPTPPAVTPPSPKG---TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 666 LEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKE---QPSKSALVS---L 719
KR A+ P + + P +V L+ K T ++E PSK L
Sbjct: 1386 PPSPKRGP-----AIPSPKGDPTSP-AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439
Query: 720 PSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQP 779
P L P SA + PS G +L P +E P P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 780 WGEMKEPPWDPKGPPKVPFRSKPTSASLKREGIS------QAPIPLTASPWEDLRPSPLS 833
G P P P +V P + S +R+ I+ P T +P E L P ++
Sbjct: 1500 MGAPTLPAVIPSSPKEV-----PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT 1554
Query: 834 ETLISKMEATARASQQPKR-VSQEPMRMPAQHPLATVGSSS--EILLP 878
K A + P S+E PA P G+ S E+L+P
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Score = 72.0 bits (175), Expect = 2e-12
Identities = 77/266 (28%), Positives = 96/266 (36%), Gaps = 38/266 (14%)
Query: 363 APYPPAACLSTP----------YSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKA 412
AP PPAA +P ++ P P G P P P+ S K
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998
Query: 413 PFLVDQSQKLPAVPASSWKPPPGLAPPQKAP---AASAPPRKAPAVPAPSQKAPAVPAPS 469
+ P PA + PP P P AS PP P P S A +P +
Sbjct: 999 GPATPSPKGAPTPPAVT--PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
Query: 470 QKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTA--PKK 527
PA PS K A+ S + A P PP TPP + P+ P+ P+ A P A P
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGA---PTPPAATPPSPKGGPATPS-PKGAPMPPAATPPS 1112
Query: 528 KSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGR-AVLERSQSGGKP 586
L P K PT+P A +PP+ +G L P G P A S GG
Sbjct: 1113 PKGGLATPPHKGAPTTP-----AATPPSPKGGLA---TPPPKGAPTTPAATPPSPKGGLA 1164
Query: 587 EPVVTVRTQETDVVEMTTQAKSPESP 612
P TT A +P SP
Sbjct: 1165 TP--------PPKGAPTTPAATPPSP 1182
Score = 71.2 bits (173), Expect = 4e-12
Identities = 82/265 (30%), Positives = 102/265 (38%), Gaps = 56/265 (21%)
Query: 368 AACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPA 427
A LS SS + R P G P P P+ S K PA P+
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG---------PATPS 958
Query: 428 SSWKP-PPGLAPPQK--APA------ASAPPRKAPAVPAPSQKAPAVPAP--SQKAPAIP 476
W P PP PP PA A PP P P + PA P+P + PA+
Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP---KGGPATPSPKGAPTPPAVT 1015
Query: 477 APSRKAS-AASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPA- 534
PS K S AA+ P+ AS PP TPP + +P+ +P+ A PT P + LP+
Sbjct: 1016 PPSPKGSPAATPFPKGAS---TPPAATPPSPKGSPAATPLPKGA--PTTP---AATLPSP 1067
Query: 535 ------PSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIP-GRAVLERSQSGGKPE 587
PS K PT P A +PP+ +G G P G P A S GG
Sbjct: 1068 KGGPATPSLKGAPTPP-----AATPPSPKG---GPATPSPKGAPMPPAATPPSPKGGLAT 1119
Query: 588 PVVTVRTQETDVVEMTTQAKSPESP 612
P TT A +P SP
Sbjct: 1120 P--------PHKGAPTTPAATPPSP 1136
Score = 69.3 bits (168), Expect = 2e-11
Identities = 84/303 (27%), Positives = 117/303 (38%), Gaps = 53/303 (17%)
Query: 293 SSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTEDLMDSGG 352
SSPK C + A+ + ++ + SP G S+ P T+
Sbjct: 765 SSPKECPTEDSGASATASSKGTLTYLADSPSPLGV------SVSPQTKRPPTKKGSAGPD 818
Query: 353 STLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKA 412
+ + + +S P P P +S+ K P +H P PP + AP+ +
Sbjct: 819 TPIGNLSS---PVSPVEASFLPENSLSFQGSKDSPATTHS-PTPPSPKGAPTPSAVT--- 871
Query: 413 PFLVDQSQKLPAVPASSWKPPPGLA-PPQKAPAASAP----PRKAPAVPAPSQKAPAVPA 467
P S P G+ PP++ P S P++ PA PAP Q APA+
Sbjct: 872 -------------PLS----PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ-APALSM 913
Query: 468 PS---QKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTA 524
S +KA A PAP K AS SP+ A P PP TPP + P+ P+ P A
Sbjct: 914 TSSSPKKARATPAP--KGIPASPSPKGA---PTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 525 PKKKSLLLPA-PSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSG 583
PA PS K PT P A +PP+ +G G P G P +
Sbjct: 969 TPPSPKGGPATPSPKGAPTPP-----AATPPSPKG---GPATPSPKGAPTPPAVTPPSPK 1020
Query: 584 GKP 586
G P
Sbjct: 1021 GSP 1023
Score = 68.2 bits (165), Expect = 3e-11
Identities = 82/269 (30%), Positives = 107/269 (39%), Gaps = 67/269 (24%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMG-SHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQK 421
AP PPAA +P K GP S +G PP PS + PF
Sbjct: 985 APTPPAATPPSP---------KGGPATPSPKGAPTPPAVTPPSPKGSPAATPF------- 1028
Query: 422 LPAVPASSWKPPPGLAP-PQKAPAASAPPRKAP-----AVPAPSQKAPAVPA--PSQKAP 473
P + PP P P+ +PAA+ P+ AP +P+P + PA P+ + P
Sbjct: 1029 ----PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP-KGGPATPSLKGAPTPP 1083
Query: 474 AIPAPSRKASAASASPRKASAVPAPPQKTP---------PPSQKAPSVPTIPQKAVSPTA 524
A PS K A+ SP+ A P PP TP PP + AP+ P A +P +
Sbjct: 1084 AATPPSPKGGPATPSPKGA---PMPPAATPPSPKGGLATPPHKGAPTTP-----AATPPS 1135
Query: 525 PKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGR-AVLERSQSG 583
PK L P K PT+P A +PP+ +G L P G P A S G
Sbjct: 1136 PKGG---LATPPPKGAPTTP-----AATPPSPKGGLA---TPPPKGAPTTPAATPPSPKG 1184
Query: 584 GKPEPVVTVRTQETDVVEMTTQAKSPESP 612
G P + TT A +P SP
Sbjct: 1185 GLATP--------SPKGAPTTPAATPPSP 1205
Score = 60.5 bits (145), Expect = 7e-09
Identities = 82/287 (28%), Positives = 105/287 (36%), Gaps = 40/287 (13%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQ---KAPSGLVTSCKAPFLVDQS 419
AP PPA +P +G P G+ P P S +CK V Q+
Sbjct: 1613 APTPPAVTPPSP----EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668
Query: 420 QK-LPAVPASSWKPPPGLAP-PQKAPAASAPPRKAPAV-----------PAPSQKAPAVP 466
K LPA + +AP P+ P +AP RK P P PS K +
Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Query: 467 APSQKAPAIPAPSRKASAASASPRKASAVP----APPQ---KTPPPSQKAPSVPTIPQKA 519
S APA P +K S+ +A + AS P APP+ TP + V P+ A
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 520 VSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPA------SRGKLPGDFDVLPTGIPG 573
AP L APS +PT P + Q S P S+ P D D L IP
Sbjct: 1789 SVSAAPSPPVSLPLAPS--PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPP 1846
Query: 574 RAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKES 620
+ SGG P V V + S + P T K S
Sbjct: 1847 EPI-----SGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGS 1888
Score = 48.1 bits (113), Expect = 4e-05
Identities = 67/288 (23%), Positives = 107/288 (37%), Gaps = 29/288 (10%)
Query: 343 DTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQG----PGPPP 398
+T L S ++++A P P C P +A P S P P
Sbjct: 22 ETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP 81
Query: 399 CQKAPSG----LVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKA-PAASAPPRKAP 453
++ SG L T+ +AP + P PA+ P +AP K P++SAP
Sbjct: 82 FPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVA 141
Query: 454 AVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAP-----PQKTPPPSQK 508
P QK+ A P +P A + S + S A + P P + P +
Sbjct: 142 LAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG 201
Query: 509 APSVP----TIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDF 564
PS P T+P V+P A + + +LP + +A++ P +
Sbjct: 202 TPSPPCIVSTVPYHCVTPMASIQSGV-------ASLPQTTPTTTLAIASPQVKDTTISSV 254
Query: 565 DVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESP 612
+ P PG L+ S P +++ TQ VV + + P +P
Sbjct: 255 LISPQN-PGSLSLKGPVS---PPAALSLSTQSLPVVTSSQKTAGPNTP 298
Score = 44.7 bits (104), Expect = 4e-04
Identities = 111/529 (20%), Positives = 166/529 (31%), Gaps = 92/529 (17%)
Query: 352 GSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCK 411
G SS S L A+ + T + G + AGP+ S L+T
Sbjct: 602 GKPASSMTSPLGVNSSASVIKTDSYA---GPDSAGPL-------------LKSSLITPTV 645
Query: 412 APFLVDQSQKLPAVP--ASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPS 469
A F ++ + P A A P S P+ P P VP S
Sbjct: 646 AAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS 705
Query: 470 QKAPAIPAPSRKASAASA---SPRKASAVPA---PPQKTPPPSQKAPSVPTIPQKAVSPT 523
+ P P+P + + +P +VP+ PP TPP ++K + A +
Sbjct: 706 ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
Query: 524 APKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSG 583
+PK+ PTE A + +S+G L +
Sbjct: 766 SPKE---------------CPTEDSGASATASSKGTL-------------------TYLA 791
Query: 584 GKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLE 643
P P+ + +T + P++P + S E +L +F+G
Sbjct: 792 DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSL-SFQGSKDSP 850
Query: 644 DWAHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMI 703
H SP P + + K + + P +E P V +
Sbjct: 851 ATTH-------SPTPPSPKGAPTPSAVTPLSPKGVTL--PPKETPTPSVVNLPFPKEGPA 901
Query: 704 TANSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHT 763
T K+ P+ S S P +A AT +P+ P +G P P S
Sbjct: 902 TPAPKQAPALSMTSSSPK------KARATPAPKGIPASPSP----KGAPTPPAATPPS-- 949
Query: 764 WVKEGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASP 823
+G K P PP PKG P P P A +P A+P
Sbjct: 950 --PKGGPATPSPKWAPTPPAATPP-SPKGGPATP---SPKGAPTPPAATPPSPKGGPATP 1003
Query: 824 WEDLRPSPLSETLISKMEATAR------ASQQPKRVSQEPMRMPAQHPL 866
P+P + T S + A AS P P PA PL
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Score = 38.5 bits (88), Expect = 0.029
Identities = 77/330 (23%), Positives = 107/330 (32%), Gaps = 41/330 (12%)
Query: 260 PDRTHTQIRLPEKTSITTWTIFSIISSTANQTQSSPKACTS---ASDEATGQGHVVESPS 316
P T T + TI S++ S N S K S A +T VV S
Sbjct: 231 PQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQ 290
Query: 317 HCVSADSPDGFFLGSCSSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYS 376
++P F + S L P HQ + + G T SA S + S+ +
Sbjct: 291 KTAGPNTPPDFPISLGSHLAPL--HQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA 348
Query: 377 SIPRGREKAGPMGSHQGPGP----------PPCQKAPSGLVTSCKAPFLVDQSQKLPAVP 426
S P R P+ S P P K PS + + +P S L
Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSP-----SGSLNVAT 403
Query: 427 ASSWKPPPGLAPPQKAPAASAPPRKAP-----------AVPAPSQKAPAVPAPSQKAPAI 475
+ S P L A P A V P A A + A +
Sbjct: 404 SFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCV 463
Query: 476 PAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKK------- 528
P ++ P +A+ P PS + + IP VSP P +
Sbjct: 464 SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIP---VSPPLPDPEDLKNLPS 520
Query: 529 SLLLPAPSQKALPTSPTEYQMALSPPASRG 558
S+L+ P+QK L T P + A PA G
Sbjct: 521 SVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
Score = 34.7 bits (78), Expect = 0.42
Identities = 56/219 (25%), Positives = 81/219 (36%), Gaps = 37/219 (16%)
Query: 364 PYPPAACLSTPYSSIP---RGREKAGP---------MGSHQGPGPPPC--------QKAP 403
P P A LS S+P ++ AGP +GSH P Q P
Sbjct: 269 PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGP 328
Query: 404 SGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAP-PRKAPAVPAPSQKA 462
S L VD S + P+ PP + + PA A P AP+V K
Sbjct: 329 SALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSV----DKG 384
Query: 463 PAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSP 522
P+ + +P+ A++ S SP + + + P T P V +P +V
Sbjct: 385 PSTISSITCSPS--GSLNVATSFSLSPTTSLILKSSPNAT----YHYPLVAQMPVSSVGT 438
Query: 523 TAPKKKSLLLPAPSQ-KALPTSPTEYQMALSPPASRGKL 560
T L++ P A PT+ E +SPP S G +
Sbjct: 439 TP-----LVVTNPCTIAAAPTTTFEVATCVSPPMSSGPI 472
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 78.2 bits (191), Expect = 3e-14
Identities = 117/508 (23%), Positives = 180/508 (35%), Gaps = 73/508 (14%)
Query: 394 PGPPPCQ----KAPSGLVTSCKAPFLVDQSQKLPAVP------ASSWKPPPGLAPPQKAP 443
P PP + K P V +V++ ++P P PP + P +K P
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP 10511
Query: 444 AA-----SAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRK--ASAVP 496
APP K P P VP P K P +P +A P K A+P
Sbjct: 10512 VPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP 10571
Query: 497 APPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPAS 556
P+ PP +AP +P+K V P AP KK + P +A E ++ + PP
Sbjct: 10572 PKPESPPPEVPEAPK-EVVPEKKV-PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKK 10629
Query: 557 RGKLPGDFDVLP-TGIPGRAVLER-SQSGGKPEPVVTVRTQETDVVE---MTTQAKSPES 611
P +P +P + V E P P V +E + E + P +
Sbjct: 10630 PEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAA 10689
Query: 612 PFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKR 671
P VT K + + V + P+LP V+ E+ K
Sbjct: 10690 PPQVTVPPKKPVPEKKAPAVV--------------------AKKPELPPVKVPEVP--KE 10727
Query: 672 WVKAKELAVEGPSQEHSRPFSV-----EALTLTKLMITANSKEQPSKSALVSLPSWLLAT 726
V K++ + P + + P V E + K+ + + P+K V L
Sbjct: 10728 VVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK 10787
Query: 727 PQASATSMMASVP----------SRPGQLSLLEGKPVVVREQPESHT---WVKEGKRPWG 773
P S P + +++ E KPV V E+ E V E +
Sbjct: 10788 PAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKII 10847
Query: 774 EMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLS 833
K+ P + E P PPK P +P K + + P P A P ED++
Sbjct: 10848 PEKKVPVIKKPEAP-----PPKEP---EPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQ 10899
Query: 834 ETLISKMEATARASQQPKRVSQEPMRMP 861
I K + + Q P++V P+++P
Sbjct: 10900 LKAIPKKKVPEK-PQVPEKVELTPLKVP 10926
Score = 62.0 bits (149), Expect = 2e-09
Identities = 105/401 (26%), Positives = 146/401 (36%), Gaps = 61/401 (15%)
Query: 387 PMGSHQGPGPPPCQK-APSGLVTSC-KAPFLVDQSQKLPAVPASSWKPPPGLAP--PQK- 441
P+ + P P P +K AP V K P +K+P + KPPP P P+K
Sbjct: 9957 PVPEEKKPVPVPKKKEAPPAKVPEVPKKP-----EEKVPVLIPKKEKPPPAKVPEVPKKP 10011
Query: 442 APAASAP---PRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAP 498
P P P+K A PA + P P P +K P +PAP + A P K VP
Sbjct: 10012 VPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVP-VPAPKK----VEAPPAK---VPEV 10063
Query: 499 PQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALP-TSPTEYQMALSP---- 553
P+K P +K VP +A P PKK+ P P ALP ++ + P
Sbjct: 10064 PKKLIPEEKKPTPVPK-KVEAPPPKVPKKRE---PVPVPVALPQEEEVLFEEEIVPEEEV 10119
Query: 554 -PASRGKLPGDFDVLPTG---IPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSP 609
P LP + +VLP +P + + PE +E E P
Sbjct: 10120 LPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKP 10179
Query: 610 ESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSP-DLPGVRSKELEQ 668
+ P E K K+VT E K EE P +P V K E+
Sbjct: 10180 KVPVPAPVPEIK-------KKVT----------EKKVVIPKKEEAPPAKVPEVPKKVEEK 10222
Query: 669 RKRWVKAKE-LAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPS------KSALVSLPS 721
R K +E L VE + P S E + I + P K A+ P+
Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPT 10282
Query: 722 WLLATPQASATSMMASVPSR--PGQLSLLEGKPVVVREQPE 760
+ +A + +P P + E P V E P+
Sbjct: 10283 PVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPK 10323
Score = 60.1 bits (144), Expect = 9e-09
Identities = 112/504 (22%), Positives = 171/504 (33%), Gaps = 77/504 (15%)
Query: 364 PYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLP 423
P PP P + +P + A P PP + P + F + L
Sbjct: 10623 PVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV-------FEEPEEVALE 10675
Query: 424 AVPASSWKPPPGLAPPQKA--PAASAPPRKAPAVPA-----PSQKAPAVP---APSQKAP 473
PA + P APPQ P P +KAPAV A P K P VP P +K P
Sbjct: 10676 EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVP 10735
Query: 474 AIPAPSRKASAASASPRKASAVP----APPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKS 529
+ +A A VP A P+K P K P VP P P P +
Sbjct: 10736 LVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPER 10795
Query: 530 LLLPAPS-----QKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIP--GRAVLERSQS 582
P P ++ P + P + + P +V P +P + ++ +
Sbjct: 10796 AESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEP---EVPPPAVPEEPKKIIPEKKV 10852
Query: 583 G--GKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQG 640
KPE + V+E P P KE I Q K + + +
Sbjct: 10853 PVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKP 10912
Query: 641 KLEDWAHWAKLEERSPDLPGVRSK-------ELEQRKRWVKAKELAVEGPSQEHSRPFSV 693
++ + K+E +PG K + K V K + + P +E + V
Sbjct: 10913 QVPE-----KVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPK---V 10964
Query: 694 EALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPV 753
E L K+ A + P K P + P + P++ ++ KP
Sbjct: 10965 EPKKLEKVKKPAVPEPPPPK------PVEEVEVPTVTKRERKIPEPTKVPEI-----KPA 11013
Query: 754 VVREQPESHTWVKEGKRPWGEMKEQPWGEMKEPPWDPK-----GPPKVPFRSKPTSASLK 808
+ PE +P E+K +K PP +P+ P VP K A
Sbjct: 11014 IPLPAPEPK------PKPEAEVK-----TIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAP 11062
Query: 809 REGISQAPIPLTASPWEDLRPSPL 832
+E ++ P+ P + PSP+
Sbjct: 11063 KEEAAKPKGPIKGVPKK--TPSPI 11084
Score = 57.0 bits (136), Expect = 8e-08
Identities = 104/482 (21%), Positives = 185/482 (38%), Gaps = 86/482 (17%)
Query: 451 KAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAP 510
+ P P P +K P VP P +K AP K P + V P ++ PPP+ K P
Sbjct: 9952 EVPRKPVPEEKKP-VPVPKKK----EAPPAKVPEVPKKPEEKVPVLIPKKEKPPPA-KVP 10005
Query: 511 SVP-----------TIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGK 559
VP +P+K +P A + P P +K +P + + +PPA +
Sbjct: 10006 EVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVE---APPAKVPE 10062
Query: 560 LPGDF---DVLPTGIPGR--AVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
+P + PT +P + A + +P PV QE +V + + PE
Sbjct: 10063 VPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEV--LFEEEIVPEEEVL 10120
Query: 615 VTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVK 674
++E ++ + +EV L E LP +E+ + V
Sbjct: 10121 PEEEE----VLPEEEEV-------------------LPEEEEVLP--EEEEIPPEEEEVP 10155
Query: 675 AKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSM 734
+E V P +E P E L K + + P V+ ++ + + +
Sbjct: 10156 PEEEYV--PEEEEFVP-EEEVLPEVKPKVPVPA-PVPEIKKKVTEKKVVIPKKEEAPPAK 10211
Query: 735 MASVPSRPGQLSLL-----EGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEPPWD 789
+ VP + + ++ E PV V E+PE +E E+ E+P +
Sbjct: 10212 VPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEE------EIPEEPPSIEEVEEVA 10265
Query: 790 PKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKMEATARASQQ 849
P P+V ++ P + + + + P ++ E+ P P+ + K A+ +
Sbjct: 10266 PPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQK----KEAPPAKVPEV 10321
Query: 850 PKRVSQEPMRMPAQHPL------------ATVGSSSEILLPMLLELETVRNTATKAEEIQ 897
PK+V ++ + +P + + +V E+++ LELE V + EEI
Sbjct: 10322 PKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVE---AEVEEIP 10378
Query: 898 EE 899
EE
Sbjct: 10379 EE 10380
Score = 55.5 bits (132), Expect = 2e-07
Identities = 106/491 (21%), Positives = 173/491 (35%), Gaps = 76/491 (15%)
Query: 448 PPRKAPAV---PAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPP 504
PP K P + PAP + AP VP P + P PAP P + VP P ++
Sbjct: 9284 PPPKVPELPEKPAPEEVAP-VPIPKKVEP--PAPKVPEVPKKPVPEEKKPVPVPKKEPAA 9340
Query: 505 PSQKAPSVPTIPQKAVS----PTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKL 560
P P VP +P+K V P KK PA + TE ++ +
Sbjct: 9341 P----PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPP 9396
Query: 561 PGDFDVLPTGIP-GRAVLERSQSGGKPEPVVTVR-----TQETDVVEMTTQAKSPESPFT 614
P ++ +P R + R + P P V +E V + K+P
Sbjct: 9397 PAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAE 9456
Query: 615 VTKK-----------ESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRS 663
V+KK E + Q EVT + E+W++ EE + R
Sbjct: 9457 VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAE---EEWSY--SEEEEGVSISVYRE 9511
Query: 664 KELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWL 723
+E E+ + + +E P E + KL I + E +
Sbjct: 9512 EEREEEEEAEVTEYEVMEEPE---------EYVVEEKLHIISKRVEAEPAEVTERQEKKI 9562
Query: 724 LATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEM 783
+ P+ A P + E +V E+ K+ K P ++ E+P
Sbjct: 9563 VLKPKIPAKI------EEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEP---- 9612
Query: 784 KEPPWDPKGPPKVPFRSKPTSASLKREGI--------------SQAPIPLTASPWEDLRP 829
K+P + K PPKV +P A + + +AP P P E R
Sbjct: 9613 KKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAP-PKARVPEEPKRA 9671
Query: 830 SPLSETLISKMEATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLELETVRNT 889
P + L K + R + P +V++ R+ + ++ E P ++ T+
Sbjct: 9672 VPEEKVLKLKPK---REEEPPAKVTEFRKRVVKEEKVSIEAPKRE---PQPIKEVTIMEE 9725
Query: 890 ATKAEEIQEES 900
+A ++EE+
Sbjct: 9726 KERAYTLEEEA 9736
Score = 51.6 bits (122), Expect = 3e-06
Identities = 102/452 (22%), Positives = 158/452 (34%), Gaps = 63/452 (13%)
Query: 447 APPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPS 506
APP K P VP ++ + ++ P P +P P
Sbjct: 10207 APPAKVPEVPKKVEEKRIILPKEEEV----LPVEVTEEPEEEPISEEEIPEEPPSIEEVE 10262
Query: 507 QKAPS-VPTIPQKAV--SPTAPKKKSLLLPAPSQKALPTS--PTEYQMALSPPASRGKLP 561
+ AP VP + +KAV +PT KK PA K +P P Q +PPA ++P
Sbjct: 10263 EVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVP 10322
Query: 562 GDFDVLPTGIP---------GRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESP 612
+P GR VLE S + VV E +VVE + E
Sbjct: 10323 KKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEE 10382
Query: 613 FTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRW 672
F +E + +G+ + + KLE+ + R +++ +
Sbjct: 10383 FH-----------------EVEEYFEEGEFHEVEEFIKLEQHRVE-EEHRVEKVHRVIEV 10424
Query: 673 VKAKELAV-EGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASA 731
+A+E+ V E P P E + K T K P K +P P+
Sbjct: 10425 FEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPT---KVVPRKEPPAKVPE----VPKKIV 10477
Query: 732 TSMMASVPSRP-----GQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEP 786
VP P +L K VV PE V K+P E P ++ E
Sbjct: 10478 VEEKVRVPEEPRVPPTKVPEVLPPKEVV----PEKKVPVPPAKKP-----EAPPPKVPEA 10528
Query: 787 PWD--PKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKMEATA 844
P + P+ VP KP K + +A +P P E + P P E+ ++
Sbjct: 10529 PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVP-EAIPPKP--ESPPPEVPEAP 10585
Query: 845 RASQQPKRVSQEPMRMPAQHPLATVGSSSEIL 876
+ K+V P + P P+ + E++
Sbjct: 10586 KEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVV 10617
Score = 48.9 bits (115), Expect = 2e-05
Identities = 76/365 (20%), Positives = 138/365 (37%), Gaps = 71/365 (19%)
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPA-------VPAPS-QKAPAVPAPSQKAP- 473
P +PA +PPP P +AP P +K PA VP P + P P P +K P
Sbjct: 9566 PKIPAKIEEPPPAKVP--EAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPP 9623
Query: 474 -----AIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKK 528
P P++ ++ + A +K PP + VP P++AV P++K
Sbjct: 9624 KVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKAR---VPEEPKRAV----PEEK 9676
Query: 529 SLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQS----GG 584
L L ++ P TE++ R V E S
Sbjct: 9677 VLKLKPKREEEPPAKVTEFRK------------------------RVVKEEKVSIEAPKR 9712
Query: 585 KPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLED 644
+P+P+ +E ++E +A + E ++E + + +E + F E+
Sbjct: 9713 EPQPI-----KEVTIMEEKERAYTLEEEAVSVQREEE---YEEYEEYDYKEFEEYEPTEE 9764
Query: 645 WAHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEG-PSQEHSRPFSV--EALTLTKL 701
+ + + EER + + + + ++ + K + E P++ + P V +A+ K+
Sbjct: 9765 YDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKV 9824
Query: 702 MITANSK---------EQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKP 752
+ K E+P K + + + T A VP +P ++ E P
Sbjct: 9825 PVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVP 9884
Query: 753 VVVRE 757
V +E
Sbjct: 9885 VPRKE 9889
Score = 46.2 bits (108), Expect = 1e-04
Identities = 99/496 (19%), Positives = 183/496 (36%), Gaps = 70/496 (14%)
Query: 455 VPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPT 514
+ P + P P P + P P A P + VP P + PPP P VP
Sbjct: 9786 ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP----PKVPE 9841
Query: 515 IPQKA------VSPTAPKKKSLLLPA------PSQKALPTSPTEYQMALSPPASRGKLPG 562
P+K +S T +K+ + PA P + + ++PP ++P
Sbjct: 9842 EPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPK 9901
Query: 563 DF--------DVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
+ + + T + V E + + E +T E +VV + K PE P
Sbjct: 9902 ELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFIT----EEEVVPV-IPVKVPEVPRK 9956
Query: 615 VTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVR-----SKELEQR 669
+E K + + + KE K K EE+ P L + +K E
Sbjct: 9957 PVPEEKKPVPVPKKKEAPPAKVPEVPK--------KPEEKVPVLIPKKEKPPPAKVPEVP 10008
Query: 670 KRWVKAKELAVEGPSQEHSRPFSV-----EALTLTKLMITANSKEQPSKSALVSLPSWLL 724
K+ V +++ V P + + P V + + K+ + A K + + + +P L+
Sbjct: 10009 KKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLI 10068
Query: 725 -------------ATPQASATSMMASVP---SRPGQLSLLEGKPVVVREQ--PESHTWVK 766
P VP + P + +L + +V E+ PE +
Sbjct: 10069 PEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLP 10128
Query: 767 EGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQA--PIPLTASPW 824
E + E +E E + PP + + PP+ + + + E + + +P+ A
Sbjct: 10129 EEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVP 10188
Query: 825 EDLRPSPLSETLISKMEAT--ARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLE 882
E + + +I K E A+ + PK+V ++ + +P + + V + E + E
Sbjct: 10189 EIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISE 10248
Query: 883 LETVRNTATKAEEIQE 898
E + EE++E
Sbjct: 10249 -EEIPEEPPSIEEVEE 10263
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/158 (24%), Positives = 60/158 (37%), Gaps = 8/158 (5%)
Query: 366 PPAACL-STPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPA 424
PPA + P +P +K P+ + PP + P V K P V + ++ P
Sbjct: 9311 PPAPKVPEVPKKPVPE-EKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAP- 9368
Query: 425 VPASSWKPPPGLAPPQKAPAAS----APPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSR 480
PA + G+ +K + +PP P +P P P ++ P P
Sbjct: 9369 -PAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKV 9427
Query: 481 KASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQK 518
A P + AVP P K PP + S T+ ++
Sbjct: 9428 PALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEE 9465
Score = 45.8 bits (107), Expect = 2e-04
Identities = 67/321 (20%), Positives = 104/321 (32%), Gaps = 63/321 (19%)
Query: 374 PYSSIPRGREKAGPMGSHQGPG--PPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSW- 430
P I EK P+ + P PP + P ++ K P + P P
Sbjct: 10812 PEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV 10871
Query: 431 ---------KPPPGLAPPQKA------PAASAPPRKAPAVPAPSQKAPA----VPAPSQK 471
PPP APP++ + P +K P P +K VP +K
Sbjct: 10872 IEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKK 10931
Query: 472 APAI-----PAPSRKASAASA------------SPRKAS-----AVPAPPQKTPPPSQKA 509
+ P P + S P+K AVP PP P +
Sbjct: 10932 VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV 10991
Query: 510 PSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLP--GDFDVL 567
P+V +K PT + +P P+ + P E + PP P V
Sbjct: 10992 PTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVP 11051
Query: 568 PTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSP---------ESPFTVT-- 616
G A + ++ P+ V + +E + P E+PFT
Sbjct: 11052 VVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLK 11111
Query: 617 ------KKESKDILISQTKEV 631
KE KDI++++++ V
Sbjct: 11112 AVPLKFVKEIKDIILTESEFV 11132
Score = 32.0 bits (71), Expect = 2.7
Identities = 87/456 (19%), Positives = 167/456 (36%), Gaps = 75/456 (16%)
Query: 448 PPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQ 507
P + P P + P P AP IP +P P +K PPP +
Sbjct: 8938 PDSRVPIPTMPIRAVPPEEIPPVVAPPIPL----------------LLPTPEEKKPPPKR 8981
Query: 508 KAPSVPTIPQKAVSPTA------PKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLP 561
+ + + A A P+++ + P P +P E + +S A K+
Sbjct: 8982 IEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEI-IDVSSKAEEVKIM 9040
Query: 562 GDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQET-DVVEMTTQAKSPESPFTVTKKES 620
AV E+ Q+ K + V +E D +E+ + E P+ E
Sbjct: 9041 TITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDED 9100
Query: 621 -KDILISQTKEVTLE-----------AFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQ 668
++I + KEV E R +G E W + + + + E
Sbjct: 9101 YEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEES 9160
Query: 669 RKRWVKAKELAVEGPS-------------QEHSRPFSVEALTLTKLMITANS--KEQPSK 713
+R V AK + P ++ SR E + +TK+ + ++PS+
Sbjct: 9161 HERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSR 9220
Query: 714 SAL------VSLPSWLLATPQASATSM-MASVPSRPGQLSLLEGKPVVVREQPESHTWVK 766
+ + V +P+ S M AS +++ E + +V E+ + H +
Sbjct: 9221 TPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEE-KIHVAIS 9279
Query: 767 EGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWED 826
+ P ++ E P ++P + P +P + +P + + + + P+P E+
Sbjct: 9280 KRVEPPPKVPELP----EKPAPEEVAPVPIPKKVEPPAPKVPE--VPKKPVP------EE 9327
Query: 827 LRPSPLSETLISKMEATARASQQPKR-VSQEPMRMP 861
+P P+ + + A + + PK+ V +E + +P
Sbjct: 9328 KKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIPVP 9360
Score = 31.2 bits (69), Expect = 4.6
Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 5/91 (5%)
Query: 458 PSQKAPAVPA-PSQKAPAIPAPSRKASAA---SASPRKASAVPAPPQKTPPPSQKAPSVP 513
P + P +P P ++P P+ + KA A S SP + S P + P PS SV
Sbjct: 250 PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPS-PVRSVS 308
Query: 514 TIPQKAVSPTAPKKKSLLLPAPSQKALPTSP 544
+ + SP + LL+ + T P
Sbjct: 309 PAARISTSPIRSVRSPLLMRKTQASTVATGP 339
Score = 30.8 bits (68), Expect = 6.1
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Query: 494 AVPAPPQ-KTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQ-KALPTSPTEYQMAL 551
AV +PP+ K+P P K+P P++ SP K++ +P++ K PT ++
Sbjct: 32659 AVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAV---SPTETKPTPTEKVQHLPVS 32715
Query: 552 SPP 554
+PP
Sbjct: 32716 APP 32718
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 75.1 bits (183), Expect = 3e-13
Identities = 81/298 (27%), Positives = 111/298 (37%), Gaps = 30/298 (10%)
Query: 337 PCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGP 396
PC L T SS A+ P P A S P +P P+ + P
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATP-PPQAPPALASPPLQGLPS--PPLSPLATPPPQAP 622
Query: 397 P-----PCQKAPSGLVTSCKAPFLVDQSQKLPAVPA----SSWKPPPGLAPPQKAP-AAS 446
P P Q PS + +P Q A+ + + PPP +PP +AP +
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPPVQAPFSPP 680
Query: 447 APPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPS 506
A P +P+ PSQ P++ AP + P P S S ++ P +A PP PP
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA-----PPPLAAPPL 735
Query: 507 QKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMA-------LSPPASRGK 559
Q PS P P + S T P + LL AP + P+ P M+ +PPA
Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
Query: 560 LPGDFDVLPTGIPGRAVLERSQSGGKP-EPVVTVRTQETDVVEMTTQAKSPESPFTVT 616
P PG+A S S P P+ T Q V+ P P + T
Sbjct: 796 PLQALPSPPASFPGQAPF--SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Score = 69.3 bits (168), Expect = 2e-11
Identities = 143/628 (22%), Positives = 211/628 (33%), Gaps = 116/628 (18%)
Query: 287 TANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTED 346
T+ T +P + A G + P+ P G S+ H TE
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE---GPRKSVSSASEHSTTEP 220
Query: 347 LMDSGGSTLSSAASGLAPYPPAACLS---TPYSSIPRGREKAGPMGSHQGPGPPPCQKAP 403
S + +A G P + LS TP SS R A G+ + P P Q P
Sbjct: 221 ---SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA--RGTPRAPAHPS-QPKP 274
Query: 404 SGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPR--KAPAVPAPSQK 461
GL Q+ + P V P L P +P A+ P KA VP P
Sbjct: 275 KGL-----------QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA 323
Query: 462 APAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKA-- 519
A +PA +P + P A + ++P +P+PP PPSQ PS+ T P +A
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP--ATPPSQAPPSMTTPPMQAPP 381
Query: 520 -------------------VSPTAPKKKSLL-----LPAPSQKA----LPTSPTEYQMAL 551
+P +P S L L +P+ +A L SP + Q +L
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
Query: 552 SPPASRGKLPGDFDVL--PTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSP 609
+ P+ P D L P +P L+ S S A SP
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS----------------------PAVSP 479
Query: 610 -ESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQ 668
SP T+ ++ L S + + L + LE + A ++P + + LE
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLI-MPPLETQSSLAPPSLQTPP-ASLTTPPLEN 537
Query: 669 RKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQ 728
P Q S P + L + P+ L + PS L P
Sbjct: 538 LPS-------LAPPPLQTASAPLTTPHL---------ETPPCPAPCPLQAPPSPLTTPPP 581
Query: 729 ASATSMMASVPSRPGQLSL--LEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEP 786
+ +S+ P P L+ L+G P P S + P ++ P
Sbjct: 582 ETPSSIATPPPQAPPALASPPLQGLP----SPPLSPLATPPPQAP----PXLALPPLQAP 633
Query: 787 PWDPKGPPKVPFRSKPTSA------SLKREGISQAPIPLTASPWEDLRPSPLSETLISKM 840
P P PP P + A L + S P P +P+ P+S +
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 841 EATARASQQPKRVSQEPMRMPAQHPLAT 868
+A + P +V P P P AT
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Score = 56.6 bits (135), Expect = 1e-07
Identities = 72/288 (25%), Positives = 103/288 (35%), Gaps = 38/288 (13%)
Query: 356 SSAASGLAPYPPAAC--LSTPYSSIPRGREKAGPMGSHQGPGP--------PPCQKAPSG 405
S S A PP A L+ P +P + PM P P PP Q PS
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 406 LVTSCKAPFLVDQSQKLPAV---PASSWKPPPGLAPPQK----------APAASAPPRKA 452
+ +P Q PA+ P + PP P Q +P A+ PP+
Sbjct: 773 PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
Query: 453 PAVPAPSQKAPAVPAPSQ-----KAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQ 507
P + AP + P P S + P P P S + A P PP ++P +
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
Query: 508 KAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPA--SRGKLPGDFD 565
P + A S P++ P A + P + ++A PA SRG P
Sbjct: 893 SGPDLAGHSSSATS--TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP---P 947
Query: 566 VLPTGIPGRAVLERSQSG-GKPEPVVTVRTQETDVVEMTTQAKSPESP 612
+ G PG + +G G + + T+ ET+ E T A P
Sbjct: 948 LAFRGAPGAPLPWPPATGPGSADGLCTI--YETEGPESATPAPGALDP 993
Score = 47.8 bits (112), Expect = 5e-05
Identities = 60/214 (28%), Positives = 88/214 (41%), Gaps = 24/214 (11%)
Query: 351 GGSTLSSAASGLAPYPPAACLSTPYSSIP--RGREKAGPMGSHQGPGPPPCQKAPSGLVT 408
GG+T+ +A P A S +S P GR + P + PGP SG T
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG--T 123
Query: 409 SCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAP 468
+ P QK + A + A AP R A + A +++ + P P
Sbjct: 124 TRPGPL----GQKGLRISAEE--------TVARGKATEAPKRSA--LSAGARRDTSGPTP 169
Query: 469 SQKAPAIPAPSRKASAASASPRKA-SAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKK 527
+PA+ SR A PR A SA P PP + P S + S + + SP A ++
Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRR 227
Query: 528 KSL--LLPAPSQKALPTSPTEYQM-ALSPPASRG 558
S L P+ ++L +S T A S P++RG
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Score = 41.6 bits (96), Expect = 0.003
Identities = 81/349 (23%), Positives = 121/349 (34%), Gaps = 48/349 (13%)
Query: 426 PASSWKPPPGLAPP--QKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKAS 483
P S +PPP + P + AA A RK A A +P + +A P+R A
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA----GPTRSAG 84
Query: 484 AASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAP---KKKSLLLPAPSQKAL 540
+S +P ++ PP +P + P +A T P +K L + A A
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 541 -PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGK----PEPVVTVR-- 593
+ + ALS A R D G P A+ RS++ G P P + R
Sbjct: 145 GKATEAPKRSALSAGARR-----DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 594 ------------TQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRG--- 638
E E + A+ S ++ + L S ++ A G
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 639 QGKLEDWAHWAK-----LEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSV 693
+G AH ++ L+ P K+ + + LA PS +RP
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
Query: 694 EALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRP 742
T L T PS LP LA P SA + ++PS P
Sbjct: 320 PDNAATPLPATL----PPSPPLATPLP---LAPPSPSAPPSLQTLPSPP 361
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 74.3 bits (181), Expect = 5e-13
Identities = 123/537 (22%), Positives = 176/537 (32%), Gaps = 71/537 (13%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKL 422
AP P T S P ++ P + + P + AP+ T AP +
Sbjct: 240 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTT 297
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVP---APSQKAPAVPAPSQKAPAIPAPS 479
P PA + P P K PA + P P P AP+ K PA P + AP AP
Sbjct: 298 PKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--APK 354
Query: 480 RKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAP-SQK 538
+ A P + P T PS P P +PT K+ PAP + K
Sbjct: 355 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-----PAPTTTK 409
Query: 539 ALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETD 598
+ PT+P E SP ++ P P ++ EP T +
Sbjct: 410 SAPTTPKE----PSPTTTKEPAP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 599 VVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDL 658
+P+ P T KE+ + T E KL +P+
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE---------------KLAPTTPEK 505
Query: 659 PGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKE--------- 709
P + E ELA P + A T K KE
Sbjct: 506 PAPTTPE-----------ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554
Query: 710 ---QPSKSALVSLPSWLLATPQASA-TSMMASVPSRPGQLSLLEGKPVVVREQPESHTWV 765
P + A + TP+ +A T++ P+ P + + E P +E P S T
Sbjct: 555 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCD 613
Query: 766 KEG-KRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPLTAS 822
K P G P KEP P PK P P P + PT+ + P P +
Sbjct: 614 KPAPTTPKGTAPTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 669
Query: 823 PWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMPA-QHPLATVGSSSEILLP 878
P P+ + + A PK + + PA P ++SE+ P
Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 726
Score = 64.7 bits (156), Expect = 4e-10
Identities = 97/451 (21%), Positives = 144/451 (31%), Gaps = 46/451 (10%)
Query: 408 TSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPA 467
T+ K P L + P P K P P + P P PAP+ A
Sbjct: 203 TTTKGPALTTPKEPTPTTP----KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 258
Query: 468 PSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKK 527
P + PAP+ A +P++ PAP P S PT P K +PT PKK
Sbjct: 259 PKE-----PAPTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTP-KEPAPTTPKK 308
Query: 528 KSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPT--GIPGRAVLERSQSGGK 585
+ P ++ PT+P E +P + P + PT P ++
Sbjct: 309 PA---PTTPKEPAPTTPKE----PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 586 PEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDW 645
EP T + +P+ P T K + + TKE +
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTTPKE 417
Query: 646 AHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITA 705
+E +P P + ++ KE A P + A T TK
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------PAPTTTKKPAPT 469
Query: 706 NSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVRE----QPES 761
KE + + P+ + + + P +P + E P E PE
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529
Query: 762 HTWVKEGKRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPL 819
KE KEP P PK P P P + PT+ + P P
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589
Query: 820 TASPWEDLRPSPLSETLISKMEATARASQQP 850
T +P+P + E T+ +P
Sbjct: 590 TPK-----KPAPKELAPTTTKEPTSTTCDKP 615
Score = 63.5 bits (153), Expect = 8e-10
Identities = 121/522 (23%), Positives = 175/522 (33%), Gaps = 78/522 (14%)
Query: 157 QEPAPTWTPRTTRTAPLD----MPLAEAPASTWHLQDQPISRHAVRVAERNFPHKTVAAQ 212
+EPAPT TAP P AP + + + P T +A
Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397
Query: 213 RQRKAKALKRSFKSQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDPRPDRTHTQIRLPEK 272
K A + KS P + E A K + P P K
Sbjct: 398 TTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456
Query: 273 TSITTWTIFSIISSTANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSC 332
T T A T P T T + + ++ +P+ +
Sbjct: 457 EPAPTTT-----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511
Query: 333 SSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQ 392
L P + T + T AA+ P PA +TP P ++ P +
Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPKEPAPTTPKE 569
Query: 393 GPGPPPCQKAPSGLV----TSCKAPFLVDQSQKLPAVPASSW--KPPP----GLAPPQ-K 441
P AP+ L T+ K P + + P S+ KP P G AP K
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629
Query: 442 APAASAPPRKAPAVPA---------PSQKAPAVPAPSQKAPAI-----------PAPSRK 481
PA + P AP P P+ P PAP + AP PAP+
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689
Query: 482 ASAASASPRKASAV----PAPPQ-KTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPS 536
A +P++ + PAP +TPPP+ S PT ++ PT K P S
Sbjct: 690 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKS----PDES 742
Query: 537 QKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQE 596
L PT + SP K PG +PT ++ + KPE T + +
Sbjct: 743 TPELSAEPTPKALENSP-----KEPG----VPT--------TKTPAATKPEMTTTAKDKT 785
Query: 597 TD-----VVEMTTQA-KSPESPFTVTKKESKDILISQTKEVT 632
T+ E TT A K + T T+K ++ + + T +VT
Sbjct: 786 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 827
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 74.3 bits (181), Expect = 5e-13
Identities = 123/537 (22%), Positives = 176/537 (32%), Gaps = 71/537 (13%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKL 422
AP P T S P ++ P + + P + AP+ T AP +
Sbjct: 281 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTT 338
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVP---APSQKAPAVPAPSQKAPAIPAPS 479
P PA + P P K PA + P P P AP+ K PA P + AP AP
Sbjct: 339 PKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--APK 395
Query: 480 RKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAP-SQK 538
+ A P + P T PS P P +PT K+ PAP + K
Sbjct: 396 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-----PAPTTTK 450
Query: 539 ALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETD 598
+ PT+P E SP ++ P P ++ EP T +
Sbjct: 451 SAPTTPKE----PSPTTTKEPAP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 599 VVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDL 658
+P+ P T KE+ + T E KL +P+
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE---------------KLAPTTPEK 546
Query: 659 PGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKE--------- 709
P + E ELA P + A T K KE
Sbjct: 547 PAPTTPE-----------ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595
Query: 710 ---QPSKSALVSLPSWLLATPQASA-TSMMASVPSRPGQLSLLEGKPVVVREQPESHTWV 765
P + A + TP+ +A T++ P+ P + + E P +E P S T
Sbjct: 596 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCD 654
Query: 766 KEG-KRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPLTAS 822
K P G P KEP P PK P P P + PT+ + P P +
Sbjct: 655 KPAPTTPKGTAPTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 710
Query: 823 PWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMPA-QHPLATVGSSSEILLP 878
P P+ + + A PK + + PA P ++SE+ P
Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 767
Score = 64.7 bits (156), Expect = 4e-10
Identities = 97/451 (21%), Positives = 144/451 (31%), Gaps = 46/451 (10%)
Query: 408 TSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPA 467
T+ K P L + P P K P P + P P PAP+ A
Sbjct: 244 TTTKGPALTTPKEPTPTTP----KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 299
Query: 468 PSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKK 527
P + PAP+ A +P++ PAP P S PT P K +PT PKK
Sbjct: 300 PKE-----PAPTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTP-KEPAPTTPKK 349
Query: 528 KSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPT--GIPGRAVLERSQSGGK 585
+ P ++ PT+P E +P + P + PT P ++
Sbjct: 350 PA---PTTPKEPAPTTPKE----PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402
Query: 586 PEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDW 645
EP T + +P+ P T K + + TKE +
Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTTPKE 458
Query: 646 AHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITA 705
+E +P P + ++ KE A P + A T TK
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------PAPTTTKKPAPT 510
Query: 706 NSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVRE----QPES 761
KE + + P+ + + + P +P + E P E PE
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570
Query: 762 HTWVKEGKRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPL 819
KE KEP P PK P P P + PT+ + P P
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630
Query: 820 TASPWEDLRPSPLSETLISKMEATARASQQP 850
T +P+P + E T+ +P
Sbjct: 631 TPK-----KPAPKELAPTTTKEPTSTTCDKP 656
Score = 63.5 bits (153), Expect = 8e-10
Identities = 121/522 (23%), Positives = 175/522 (33%), Gaps = 78/522 (14%)
Query: 157 QEPAPTWTPRTTRTAPLD----MPLAEAPASTWHLQDQPISRHAVRVAERNFPHKTVAAQ 212
+EPAPT TAP P AP + + + P T +A
Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438
Query: 213 RQRKAKALKRSFKSQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDPRPDRTHTQIRLPEK 272
K A + KS P + E A K + P P K
Sbjct: 439 TTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497
Query: 273 TSITTWTIFSIISSTANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSC 332
T T A T P T T + + ++ +P+ +
Sbjct: 498 EPAPTTT-----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 333 SSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQ 392
L P + T + T AA+ P PA +TP P ++ P +
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPKEPAPTTPKE 610
Query: 393 GPGPPPCQKAPSGLV----TSCKAPFLVDQSQKLPAVPASSW--KPPP----GLAPPQ-K 441
P AP+ L T+ K P + + P S+ KP P G AP K
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670
Query: 442 APAASAPPRKAPAVPA---------PSQKAPAVPAPSQKAPAI-----------PAPSRK 481
PA + P AP P P+ P PAP + AP PAP+
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730
Query: 482 ASAASASPRKASAV----PAPPQ-KTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPS 536
A +P++ + PAP +TPPP+ S PT ++ PT K P S
Sbjct: 731 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKS----PDES 783
Query: 537 QKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQE 596
L PT + SP K PG +PT ++ + KPE T + +
Sbjct: 784 TPELSAEPTPKALENSP-----KEPG----VPT--------TKTPAATKPEMTTTAKDKT 826
Query: 597 TD-----VVEMTTQA-KSPESPFTVTKKESKDILISQTKEVT 632
T+ E TT A K + T T+K ++ + + T +VT
Sbjct: 827 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 868
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 74.3 bits (181), Expect = 5e-13
Identities = 123/537 (22%), Positives = 176/537 (32%), Gaps = 71/537 (13%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKL 422
AP P T S P ++ P + + P + AP+ T AP +
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTT 390
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVP---APSQKAPAVPAPSQKAPAIPAPS 479
P PA + P P K PA + P P P AP+ K PA P + AP AP
Sbjct: 391 PKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--APK 447
Query: 480 RKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAP-SQK 538
+ A P + P T PS P P +PT K+ PAP + K
Sbjct: 448 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-----PAPTTTK 502
Query: 539 ALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETD 598
+ PT+P E SP ++ P P ++ EP T +
Sbjct: 503 SAPTTPKE----PSPTTTKEPAP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 599 VVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDL 658
+P+ P T KE+ + T E KL +P+
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE---------------KLAPTTPEK 598
Query: 659 PGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKE--------- 709
P + E ELA P + A T K KE
Sbjct: 599 PAPTTPE-----------ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647
Query: 710 ---QPSKSALVSLPSWLLATPQASA-TSMMASVPSRPGQLSLLEGKPVVVREQPESHTWV 765
P + A + TP+ +A T++ P+ P + + E P +E P S T
Sbjct: 648 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCD 706
Query: 766 KEG-KRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPLTAS 822
K P G P KEP P PK P P P + PT+ + P P +
Sbjct: 707 KPAPTTPKGTAPTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 762
Query: 823 PWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMPA-QHPLATVGSSSEILLP 878
P P+ + + A PK + + PA P ++SE+ P
Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 819
Score = 64.7 bits (156), Expect = 4e-10
Identities = 97/451 (21%), Positives = 144/451 (31%), Gaps = 46/451 (10%)
Query: 408 TSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPA 467
T+ K P L + P P K P P + P P PAP+ A
Sbjct: 296 TTTKGPALTTPKEPTPTTP----KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 351
Query: 468 PSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKK 527
P + PAP+ A +P++ PAP P S PT P K +PT PKK
Sbjct: 352 PKE-----PAPTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTP-KEPAPTTPKK 401
Query: 528 KSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPT--GIPGRAVLERSQSGGK 585
+ P ++ PT+P E +P + P + PT P ++
Sbjct: 402 PA---PTTPKEPAPTTPKE----PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454
Query: 586 PEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDW 645
EP T + +P+ P T K + + TKE +
Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTTPKE 510
Query: 646 AHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITA 705
+E +P P + ++ KE A P + A T TK
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------PAPTTTKKPAPT 562
Query: 706 NSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVRE----QPES 761
KE + + P+ + + + P +P + E P E PE
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 762 HTWVKEGKRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPL 819
KE KEP P PK P P P + PT+ + P P
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 820 TASPWEDLRPSPLSETLISKMEATARASQQP 850
T +P+P + E T+ +P
Sbjct: 683 TPK-----KPAPKELAPTTTKEPTSTTCDKP 708
Score = 63.5 bits (153), Expect = 8e-10
Identities = 121/522 (23%), Positives = 175/522 (33%), Gaps = 78/522 (14%)
Query: 157 QEPAPTWTPRTTRTAPLD----MPLAEAPASTWHLQDQPISRHAVRVAERNFPHKTVAAQ 212
+EPAPT TAP P AP + + + P T +A
Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490
Query: 213 RQRKAKALKRSFKSQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDPRPDRTHTQIRLPEK 272
K A + KS P + E A K + P P K
Sbjct: 491 TTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549
Query: 273 TSITTWTIFSIISSTANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSC 332
T T A T P T T + + ++ +P+ +
Sbjct: 550 EPAPTTT-----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 604
Query: 333 SSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQ 392
L P + T + T AA+ P PA +TP P ++ P +
Sbjct: 605 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPKEPAPTTPKE 662
Query: 393 GPGPPPCQKAPSGLV----TSCKAPFLVDQSQKLPAVPASSW--KPPP----GLAPPQ-K 441
P AP+ L T+ K P + + P S+ KP P G AP K
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722
Query: 442 APAASAPPRKAPAVPA---------PSQKAPAVPAPSQKAPAI-----------PAPSRK 481
PA + P AP P P+ P PAP + AP PAP+
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782
Query: 482 ASAASASPRKASAV----PAPPQ-KTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPS 536
A +P++ + PAP +TPPP+ S PT ++ PT K P S
Sbjct: 783 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKS----PDES 835
Query: 537 QKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQE 596
L PT + SP K PG +PT ++ + KPE T + +
Sbjct: 836 TPELSAEPTPKALENSP-----KEPG----VPT--------TKTPAATKPEMTTTAKDKT 878
Query: 597 TD-----VVEMTTQA-KSPESPFTVTKKESKDILISQTKEVT 632
T+ E TT A K + T T+K ++ + + T +VT
Sbjct: 879 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 920
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 74.3 bits (181), Expect = 5e-13
Identities = 123/537 (22%), Positives = 176/537 (32%), Gaps = 71/537 (13%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKL 422
AP P T S P ++ P + + P + AP+ T AP +
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTT 431
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVP---APSQKAPAVPAPSQKAPAIPAPS 479
P PA + P P K PA + P P P AP+ K PA P + AP AP
Sbjct: 432 PKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--APK 488
Query: 480 RKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAP-SQK 538
+ A P + P T PS P P +PT K+ PAP + K
Sbjct: 489 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-----PAPTTTK 543
Query: 539 ALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETD 598
+ PT+P E SP ++ P P ++ EP T +
Sbjct: 544 SAPTTPKE----PSPTTTKEPAP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 599 VVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDL 658
+P+ P T KE+ + T E KL +P+
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE---------------KLAPTTPEK 639
Query: 659 PGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKE--------- 709
P + E ELA P + A T K KE
Sbjct: 640 PAPTTPE-----------ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688
Query: 710 ---QPSKSALVSLPSWLLATPQASA-TSMMASVPSRPGQLSLLEGKPVVVREQPESHTWV 765
P + A + TP+ +A T++ P+ P + + E P +E P S T
Sbjct: 689 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCD 747
Query: 766 KEG-KRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPLTAS 822
K P G P KEP P PK P P P + PT+ + P P +
Sbjct: 748 KPAPTTPKGTAPTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 803
Query: 823 PWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMPA-QHPLATVGSSSEILLP 878
P P+ + + A PK + + PA P ++SE+ P
Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 860
Score = 64.7 bits (156), Expect = 4e-10
Identities = 97/451 (21%), Positives = 144/451 (31%), Gaps = 46/451 (10%)
Query: 408 TSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPA 467
T+ K P L + P P K P P + P P PAP+ A
Sbjct: 337 TTTKGPALTTPKEPTPTTP----KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 392
Query: 468 PSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKK 527
P + PAP+ A +P++ PAP P S PT P K +PT PKK
Sbjct: 393 PKE-----PAPTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTP-KEPAPTTPKK 442
Query: 528 KSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPT--GIPGRAVLERSQSGGK 585
+ P ++ PT+P E +P + P + PT P ++
Sbjct: 443 PA---PTTPKEPAPTTPKE----PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495
Query: 586 PEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDW 645
EP T + +P+ P T K + + TKE +
Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTTPKE 551
Query: 646 AHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITA 705
+E +P P + ++ KE A P + A T TK
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------PAPTTTKKPAPT 603
Query: 706 NSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVRE----QPES 761
KE + + P+ + + + P +P + E P E PE
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 762 HTWVKEGKRPWGEMKEQPWGEMKEP-PWDPKGP-PKVPFRSKPTSASLKREGISQAPIPL 819
KE KEP P PK P P P + PT+ + P P
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 820 TASPWEDLRPSPLSETLISKMEATARASQQP 850
T +P+P + E T+ +P
Sbjct: 724 TPK-----KPAPKELAPTTTKEPTSTTCDKP 749
Score = 63.5 bits (153), Expect = 8e-10
Identities = 121/522 (23%), Positives = 175/522 (33%), Gaps = 78/522 (14%)
Query: 157 QEPAPTWTPRTTRTAPLD----MPLAEAPASTWHLQDQPISRHAVRVAERNFPHKTVAAQ 212
+EPAPT TAP P AP + + + P T +A
Sbjct: 472 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531
Query: 213 RQRKAKALKRSFKSQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDPRPDRTHTQIRLPEK 272
K A + KS P + E A K + P P K
Sbjct: 532 TTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590
Query: 273 TSITTWTIFSIISSTANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSC 332
T T A T P T T + + ++ +P+ +
Sbjct: 591 EPAPTTT-----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 645
Query: 333 SSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQ 392
L P + T + T AA+ P PA +TP P ++ P +
Sbjct: 646 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPKEPAPTTPKE 703
Query: 393 GPGPPPCQKAPSGLV----TSCKAPFLVDQSQKLPAVPASSW--KPPP----GLAPPQ-K 441
P AP+ L T+ K P + + P S+ KP P G AP K
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763
Query: 442 APAASAPPRKAPAVPA---------PSQKAPAVPAPSQKAPAI-----------PAPSRK 481
PA + P AP P P+ P PAP + AP PAP+
Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823
Query: 482 ASAASASPRKASAV----PAPPQ-KTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPS 536
A +P++ + PAP +TPPP+ S PT ++ PT K P S
Sbjct: 824 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKS----PDES 876
Query: 537 QKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQE 596
L PT + SP K PG +PT ++ + KPE T + +
Sbjct: 877 TPELSAEPTPKALENSP-----KEPG----VPT--------TKTPAATKPEMTTTAKDKT 919
Query: 597 TD-----VVEMTTQA-KSPESPFTVTKKESKDILISQTKEVT 632
T+ E TT A K + T T+K ++ + + T +VT
Sbjct: 920 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVT 961
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 73.6 bits (179), Expect = 8e-13
Identities = 125/514 (24%), Positives = 197/514 (38%), Gaps = 83/514 (16%)
Query: 381 GREKAGPMGSHQGPGPP------PCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPP 434
G E+ G + PP P ++A S + K+P +K A + K P
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 435 GLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASA 494
P K A S P K+P K+PA +KA + K+ A + SP KA +
Sbjct: 549 KAKSPAKEEAKSPPEAKSPE--KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 495 VPAPPQKTPPPSQ-------KAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEY 547
K+P ++ K+P+ P+KA SPT + KS +K SP
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP--- 663
Query: 548 QMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAK 607
+ A SP + K P E+++S K E ++ E + +AK
Sbjct: 664 EKAKSPVKAEAKSP----------------EKAKSPVKAE----AKSPEKAKSPVKEEAK 703
Query: 608 SPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELE 667
SPE + K+E+K + E + K E AK E++ +K E
Sbjct: 704 SPEKAKSPVKEEAK----------SPEKAKSPVKEE-----AKTPEKAKSPVKEEAKSPE 748
Query: 668 QRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSAL---VSLPSWLL 724
+ K KAK L V+ P E P EA + A+ + +KS + V P
Sbjct: 749 KAKSPEKAKTLDVKSP--EAKTPAKEEARS------PADKFPEKAKSPVKEEVKSPEKAK 800
Query: 725 ATPQASATSMMASVPSRPGQLSLL--EGKP--VVVREQPESHTWVKEGKRPWGEMK---- 776
+ + A + +P + S + E KP V V+E P+ K P E K
Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860
Query: 777 --EQPWGEMKEPPWDPKGPPKV--PFRSKPTSASLKREGISQAPIPLTASP-----WEDL 827
E P E +P + K P V P SK + + E + P P +P ED
Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDA 920
Query: 828 RPSPLSETLISKMEATARASQQPKRVSQEPMRMP 861
+P +T ++K E +++P + +++ P
Sbjct: 921 KPK--EKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952
Score = 40.0 bits (92), Expect = 0.010
Identities = 50/223 (22%), Positives = 80/223 (35%), Gaps = 39/223 (17%)
Query: 400 QKAPSGLVTSCKAPFL-VDQSQKLPAVPASSWKP-------PPGLAPPQKAPAA------ 445
+KA S L KAP + + +++ + KP PP A +KAPA
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 446 ------SAPPRKAPAVPAPSQKAPAVPAP-----------SQKAPAIPAPSRKASA---- 484
AP ++AP +K PAV P ++ +P P ++A A
Sbjct: 857 KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV 916
Query: 485 -ASASPRKASAV---PAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKAL 540
A P++ + V K PS+ A P+K + KK P KA
Sbjct: 917 KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK 976
Query: 541 PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSG 583
T + P A + + D + P +A +++ G
Sbjct: 977 EDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKG 1019
Score = 37.4 bits (85), Expect = 0.065
Identities = 76/308 (24%), Positives = 124/308 (40%), Gaps = 42/308 (13%)
Query: 576 VLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEA 635
V+E+S+ K +V +T+ET V E VT++E K+ + KE
Sbjct: 446 VVEKSE---KETVIVEEQTEETQVTE------------EVTEEEEKEAKEEEGKE----- 485
Query: 636 FRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEA 695
+G E+ A + E +SP S E E + KE A + P++ S P EA
Sbjct: 486 --EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS---PVKEEA-KSPAEAKS-PEKEEA 538
Query: 696 LTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVV 755
+ ++ +K P+K S P + + + P + + E K
Sbjct: 539 KSPAEVKSPEKAK-SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 756 REQPE-SHTWVKEGKRPWGEMKEQPWGEMKEP-----PWDPKGPPKVPFRSKPTSASLKR 809
+ PE + + VKE + E K E K P P K P K +S + S ++
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 810 EGISQAPIPLTA-SPWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMP--AQHPL 866
E +A P A SP + SP E S ++A A++ ++ K +E + P A+ P+
Sbjct: 658 E---EAKSPEKAKSPVKAEAKSP--EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 867 ATVGSSSE 874
S E
Sbjct: 713 KEEAKSPE 720
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 73.2 bits (178), Expect = 1e-12
Identities = 85/307 (27%), Positives = 119/307 (38%), Gaps = 20/307 (6%)
Query: 290 QTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTEDLMD 349
Q P+ D A G + SP S +P P
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT 328
Query: 350 SGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVT- 408
S GS A P PP + L+TP P A + Q P PP S L T
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAP----PALALPPLQAPPSPPASPPLSPLATP 384
Query: 409 SCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAP-AASAPPRKAPAVPAPSQKAPAVPA 467
S +AP + + L P S PPP +PP +AP + A P +P+ PSQ P++ A
Sbjct: 385 SPQAPNAL--AVHLLQAPFS---PPP--SPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 437
Query: 468 PS-QKAPAIPAPSRKASAASASPRKASAVPAPP-QKTPPPSQKAPSVPTIPQKAVSPTAP 525
P Q P+ PA + +A+ P+ + APP Q PP Q P++ T P +A+ P+ P
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL-PSPP 496
Query: 526 KKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGK 585
P +LP SP +A PP + L +P P L+ +
Sbjct: 497 ASFPGQAPFSPSASLPMSP----LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 552
Query: 586 PEPVVTV 592
P P +V
Sbjct: 553 PGPDTSV 559
Score = 73.2 bits (178), Expect = 1e-12
Identities = 81/278 (29%), Positives = 102/278 (36%), Gaps = 36/278 (12%)
Query: 358 AASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVD 417
AA L P + L+TP S P + P P PP PS TS +P L
Sbjct: 283 AAPALGPLSSSP-LATPSPSAPPS--PSAPPSLQTLPSPPATP--PSQATTSLGSPTLQA 337
Query: 418 QSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAI-- 475
LP+ P S PP PQ PA + PP +AP P S + PS +AP
Sbjct: 338 THSFLPSPPLSPLATPP----PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393
Query: 476 -----------PAPSRKA--SAASASPRKASAVP---APPQKTPPPSQKAPSVPTIPQKA 519
P+P +A S ++ P SA P APP PP Q PS P P +
Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453
Query: 520 VSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLER 579
S T P + L AP + P +PP P P PG+A
Sbjct: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP------PASFPGQAPF-- 505
Query: 580 SQSGGKP-EPVVTVRTQETDVVEMTTQAKSPESPFTVT 616
S S P P+ T Q V+ P P + T
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Score = 61.2 bits (147), Expect = 4e-09
Identities = 64/210 (30%), Positives = 81/210 (38%), Gaps = 25/210 (11%)
Query: 366 PPAACLSTPYSSIPRGRE--------KAGPMGSHQGPGPPPCQK--APSGLVTSCKAPFL 415
PP + L+TP P P Q P PP +PS S P L
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435
Query: 416 VDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAI 475
++P P +S P PP +AP A P A P P Q PA+ P P
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP-PPQAPPALATP----PLQ 490
Query: 476 PAPSRKASAASASPRKASA-VPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLP- 533
PS AS +P SA +P P TPPP +AP V P V P+ P +L P
Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPPP--QAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 534 APSQKALPTSPTEYQMALS------PPASR 557
P TS + ++ L+ PP SR
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578
Score = 55.8 bits (133), Expect = 2e-07
Identities = 72/278 (25%), Positives = 106/278 (38%), Gaps = 33/278 (11%)
Query: 355 LSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGP---GPPPCQKAPSGLVTSC- 410
+S +A+ + PP+ L+ P +P + PM P PPP P L
Sbjct: 421 VSPSATPPSQAPPS--LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Query: 411 KAP--FLVDQSQKLPAVPASSWKPPPGLAPPQKA------PAASAPPRKAPAVPAPSQKA 462
+AP Q LP+ PAS PG AP + P A+ PP+ P + AP +
Sbjct: 479 QAPPALATPPLQALPSPPASF----PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534
Query: 463 PAVPAPSQ-----KAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQ 517
P P S + P P P S + A P PP ++P + P +
Sbjct: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594
Query: 518 KAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPA--SRGKLPGDFDVLPTGIPGRA 575
A S P++ P A + P + ++A PA SRG P + G PG
Sbjct: 595 SATS--TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP---PLAFRGAPGAP 649
Query: 576 VLERSQSG-GKPEPVVTVRTQETDVVEMTTQAKSPESP 612
+ +G G + + T+ ET+ E T A P
Sbjct: 650 LPWPPATGPGSADGLCTI--YETEGPESATPAPGALDP 685
Score = 53.9 bits (128), Expect = 7e-07
Identities = 62/218 (28%), Positives = 86/218 (39%), Gaps = 35/218 (16%)
Query: 373 TPYSSIPRGREKAGPMGSHQG-PGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWK 431
TP + P ++ G+ G P P P + K+ + PA+ +
Sbjct: 159 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218
Query: 432 PPPG---LAPPQKAPAASAPPRKAPAVPAPSQKA-PAVPA-PSQ---------KAPAIPA 477
P G P ++ ++SA P +PA PS + P PA PSQ + P +
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278
Query: 478 PSRKASAA----SASPRKASAVPAPPQKTPPPS-QKAPSVPTIPQKAV-----SPTAPKK 527
P + A+ A S+SP + APP + PPS Q PS P P SPT
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338
Query: 528 KSLLLPAPSQKALPTSPTEYQMAL---------SPPAS 556
S LP+P L T P + AL SPPAS
Sbjct: 339 HS-FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375
Score = 48.5 bits (114), Expect = 3e-05
Identities = 106/470 (22%), Positives = 166/470 (35%), Gaps = 69/470 (14%)
Query: 434 PGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAP--SQKAPAIPAPSRKASAASASPRK 491
PGL P+ + PP PA A AV +++A I + SA A P +
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 492 ASAVPAPP--QKTPPPSQKAPSVPTIPQKAVSPTAPK---KKSLLLPAPSQKAL-PTSPT 545
S PA ++ PP +P + P +A T P +K L + A A +
Sbjct: 82 TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141
Query: 546 EYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGK----PEPVVTVRTQ------ 595
+ ALS A R D G P A+ RS++ G P P + R +
Sbjct: 142 PKRSALSAGARR-----DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 596 --------ETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAH 647
E E + A+ S ++ + L S ++ A G
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS------- 249
Query: 648 WAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANS 707
A+ R+P P + + + ++A P ++ + P ++ L+ + L T +
Sbjct: 250 -ARGTPRAPAHPS------QPKPKGLQALRPPQVTPPRKDAAP-ALGPLSSSPLA-TPSP 300
Query: 708 KEQPSKSA---LVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTW 764
PS SA L +LPS ATP + AT+ + S P+ S L P+ P
Sbjct: 301 SAPPSPSAPPSLQTLPS-PPATPPSQATTSLGS-PTLQATHSFLPSPPLSPLATPPPQAP 358
Query: 765 VKEGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSAS------LKREGISQAPIP 818
P ++ PP P PP P + A L + S P P
Sbjct: 359 PALALPP-----------LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407
Query: 819 LTASPWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMPAQHPLAT 868
+P+ P+S + +A + P +V P P P AT
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Score = 47.0 bits (110), Expect = 8e-05
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 20/194 (10%)
Query: 376 SSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPP- 434
++IP +AGP + + P ++AP TS P V P + + +P P
Sbjct: 68 ATIPESAPRAGPTRTSRPPASGRGERAPPAKNTS---PGPVSS----PGRASGTTRPGPL 120
Query: 435 ---GLAPPQKAPAASAPPRKAP---AVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASAS 488
GL + A +AP A+ A +++ + P P +PA+ SR A
Sbjct: 121 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 180
Query: 489 PRKA-SAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSL--LLPAPSQKALPTSPT 545
PR A SA P PP + P S + S + + SP A ++ S L P+ ++L +S T
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 546 EYQM-ALSPPASRG 558
A S P++RG
Sbjct: 239 PLSSPARSGPSARG 252
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 72.0 bits (175), Expect = 2e-12
Identities = 71/275 (25%), Positives = 106/275 (38%), Gaps = 16/275 (5%)
Query: 349 DSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGP-GPPPCQKAPSGLV 407
D+ GS ++SA + P A P + P G P+ S GP P P V
Sbjct: 454 DTPGSPVTSADGPVVPVTSADIPLVPVTP-PDG--PVVPVTSADGPVAPVSSADGPVVPV 510
Query: 408 TSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPA 467
T +PF+ + VP + P P ++PA P +P VP P VP
Sbjct: 511 TPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPV 570
Query: 468 PSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPS---QKAPSVPTIP-QKAVSPT 523
S +P +P +P + VP P +P S +P+VP P V P
Sbjct: 571 TSADSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPV 630
Query: 524 APKKKSLLLPAPSQKA-LPTSPTEYQMALSPPASRGKLP---GDFDVLPTGIPGRAVLER 579
P ++ A + +P +P + + PA +P D V+P R V+
Sbjct: 631 TPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPV 690
Query: 580 SQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
+ + G+ PV T D + T A +P SP T
Sbjct: 691 TTADGRIVPV----TAAGDPIVPVTPADTPGSPVT 721
Score = 62.8 bits (151), Expect = 1e-09
Identities = 73/276 (26%), Positives = 105/276 (38%), Gaps = 29/276 (10%)
Query: 349 DSGGSTLSSAASGLAPYPPA---ACLSTPYSSIPRGREKAGPMGSHQGPGPP--PCQKAP 403
DS ++SA S + P PA L TP + GP+ P P A
Sbjct: 1254 DSPVVPVTSADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSAD 1313
Query: 404 SGLV--TSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQK 461
S +V T P + S P VP + P P +P S P ++PA+P
Sbjct: 1314 SPVVPVTPADGPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPAD 1373
Query: 462 APAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKT---PPPSQKAPSVPTIPQK 518
+P VP S +P IP + + +P VP P T P S P VP P
Sbjct: 1374 SPVVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGPVVPVTP-- 1431
Query: 519 AVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLE 578
A P P + PA + + TS + ++ P D ++P P V+
Sbjct: 1432 AGDPIVP-----VTPADTPGSPVTSADGPVVPVTTP--------DGPLVPVSPPDGPVVP 1478
Query: 579 RSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
+ + G PVV V ++ + +TT A P P T
Sbjct: 1479 VTSADG---PVVPVTPADSPFIPVTT-ADDPIVPVT 1510
Score = 61.2 bits (147), Expect = 4e-09
Identities = 67/283 (23%), Positives = 100/283 (35%), Gaps = 54/283 (19%)
Query: 349 DSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVT 408
DS +++SA S + P PA + P + GP P VT
Sbjct: 2142 DSPVISVASADSPVVPVTPADTVVVPVTPA-------------DGPVIP---------VT 2179
Query: 409 SCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAP 468
++P + P VP + P P +P PP P VP P P
Sbjct: 2180 PAESPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVA 2239
Query: 469 SQKAPAIPAPSRKASAASASPRKASAVPAPPQKT---PPPSQKAPSVP-TIPQKAVSPTA 524
S P +P S + +P + VP P + P S P P T+ V P
Sbjct: 2240 SADGPVVPVTSADSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVT 2299
Query: 525 PKKKSLLLPAPSQK-ALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIP--------GRA 575
P + +P+ +P +P + PPA+ +P V G P G
Sbjct: 2300 PADDPIFPVSPADSPVVPVTPANIPVVPVPPANGSVVP----VTSAGSPFVPIIPADGLV 2355
Query: 576 VLER---------SQSGGKP------EPVVTVRTQETDVVEMT 603
VL+ S + G P +PVV+V T ++ V+ +T
Sbjct: 2356 VLDSSTDVLVVLVSPTDGIPVPDLADDPVVSVTTSDSPVIPVT 2398
Score = 58.2 bits (139), Expect = 4e-08
Identities = 66/278 (23%), Positives = 97/278 (34%), Gaps = 26/278 (9%)
Query: 355 LSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQK-APSGLVTSCKAP 413
+++A + P PA TP S + P+ S P P P VTS P
Sbjct: 1041 VTAAGDPIVPVTPA---DTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGP 1097
Query: 414 FLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAP 473
S P VP +S P P P +P +P + P VP +P
Sbjct: 1098 VAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSP 1157
Query: 474 AIPAPSRKASAASASPRKASAVPAPPQK---TPPPSQKAPSVPTIPQKA----------- 519
+ + +P + +P PP P S +P VP IP
Sbjct: 1158 VLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLVVLDSSTDVL 1217
Query: 520 VSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLP---GDFDVLPTGIPGRAV 576
V P +P L+ + + + + PA +P D V+P V
Sbjct: 1218 VVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPADSPV 1277
Query: 577 LERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
+ + G PVV+V T + VV ++T A SP P T
Sbjct: 1278 ILVTPVG----PVVSVTTADGPVVLVST-ADSPVIPVT 1310
Score = 56.6 bits (135), Expect = 1e-07
Identities = 66/287 (22%), Positives = 102/287 (35%), Gaps = 35/287 (12%)
Query: 346 DLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSG 405
DL D +++ A S + P PA +P + P+ P P
Sbjct: 1231 DLADDPVVSVTIADSPVIPVTPA---DSPVVPVTSADSPVVPVTPADSPVILVTPVGPVV 1287
Query: 406 LVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAV 465
VT+ P ++ + P +P +S +P P P VP S +P V
Sbjct: 1288 SVTTADGPVVLVSTADSPVIPVTS----------ADSPVVPVTPADGPVVPVTSADSPFV 1337
Query: 466 PAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKT---PPPSQKAPSVP-TIPQKAVS 521
P P +P + S +P ++ A+P P + P S +P +P T V
Sbjct: 1338 PVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPADSPVVPVTSADSPLIPLTTAGSRVV 1397
Query: 522 PTAPKKKSLLLPAPSQ-----------KALPTSPTEYQMALSPPASRGKLP---GDFDVL 567
P P ++ P+ +P +P + PA P D V+
Sbjct: 1398 PVTPTGDPIVPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVV 1457
Query: 568 PTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
P P ++ S G PVV V + + VV + T A SP P T
Sbjct: 1458 PVTTPDGPLVPVSPPDG---PVVPVTSADGPVVPV-TPADSPFIPVT 1500
Score = 56.6 bits (135), Expect = 1e-07
Identities = 65/271 (23%), Positives = 96/271 (35%), Gaps = 23/271 (8%)
Query: 346 DLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPP--PCQKAP 403
DL D +++ A S + P PA +P + P+ S P P P P
Sbjct: 1860 DLADDPVVSVTIADSPVIPVTPA---DSPVVLVTPADGPVVPVTSVDNPVVPVTPADN-P 1915
Query: 404 SGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAP 463
VT P + P VP +S P P +P P +P +P S +P
Sbjct: 1916 VIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSP 1975
Query: 464 AVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPT 523
VP +P +P ++ A+P P +P + P IP A SP
Sbjct: 1976 LVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTADSPF 2035
Query: 524 APKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSG 583
P + PA S T P + + ++P D V+P + V+ + +
Sbjct: 2036 VP-----VTPADSPVIPVTPPDDLVVPVTPI--------DCPVVPVTLVDCPVVSVTPAN 2082
Query: 584 GKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
+PV T V T A SP P T
Sbjct: 2083 SPVDPV----TPADGPVVPVTPADSPVIPVT 2109
Score = 56.6 bits (135), Expect = 1e-07
Identities = 63/260 (24%), Positives = 91/260 (35%), Gaps = 53/260 (20%)
Query: 364 PYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLP 423
P P + P S+ P+ GP P VT +P + P
Sbjct: 2064 PVVPVTLVDCPVVSVTPANSPVDPVTPADGPVVP---------VTPADSPVI-------P 2107
Query: 424 AVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKAS 483
PA P P + S P +P VP +P + S +P +P
Sbjct: 2108 VTPADDLIVP---VTPADSLIVSVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTV 2164
Query: 484 AASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTS 543
+P +P P ++P++P P A SP P + PA +P +
Sbjct: 2165 VVPVTPADGPVIPVTP-------AESPAIPVTP--ADSPVVP-----VTPA-DDPVVPVT 2209
Query: 544 PTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMT 603
P + + PPAS +P V P PG V S G PVV V + ++ +V +T
Sbjct: 2210 PADSPIVPVPPASDPVVP----VTPADTPGSPV--ASADG----PVVPVTSADSPLVPVT 2259
Query: 604 ---------TQAKSPESPFT 614
T A SP P T
Sbjct: 2260 PGDSPVVPVTPADSPVFPVT 2279
Score = 56.2 bits (134), Expect = 1e-07
Identities = 63/254 (24%), Positives = 88/254 (34%), Gaps = 21/254 (8%)
Query: 364 PYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPP--PCQKAPSGLVTSCKAPFLVDQSQK 421
P P P + A P+ + GP P P P VT +P +
Sbjct: 917 PVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADD-PIVPVTPADSPVVSVTPAD 975
Query: 422 LPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRK 481
P VP +S P P P S P ++PA+P +P VP S P P +
Sbjct: 976 GPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTAD 1035
Query: 482 ASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP-QKAVSPTAPKKKSLLLPAPSQKAL 540
+ VP P TP + P +P A SP P + P +
Sbjct: 1036 GRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVP------VTPPDGPVV 1089
Query: 541 PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVV 600
P + + +A P S D V+P V S + G PVV V ++ +
Sbjct: 1090 PVTSADGPVA---PVS----SADGPVVPVTSADGPVAPVSSADG---PVVPVTPADSPFI 1139
Query: 601 EMTTQAKSPESPFT 614
+TT A P P T
Sbjct: 1140 PVTT-ADDPIVPVT 1152
Score = 54.7 bits (130), Expect = 4e-07
Identities = 69/281 (24%), Positives = 94/281 (33%), Gaps = 27/281 (9%)
Query: 349 DSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPP---------PC 399
DS ++SA S + P PA P +S P+ S GP P P
Sbjct: 1692 DSPVVLVTSADSPVIPVTPADSPVVPVTSADTD-SPGSPVTSADGPVVPVTSADSLPVPV 1750
Query: 400 QKA--PSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPA 457
A P VTS P S P VP + P P P +P VP
Sbjct: 1751 TPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPV 1810
Query: 458 PSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQK---TPPPSQKAPSVPT 514
P P VP S +P +P S VP P P + T
Sbjct: 1811 PPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVT 1870
Query: 515 IPQKAVSPTAPKKKSLLLPAPSQ-KALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPG 573
I V P P ++L P+ +P + + + PA +P V P P
Sbjct: 1871 IADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPADNPVIP----VTPVDDPV 1926
Query: 574 RAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
V +P+V V + ++ +V + T A SP P T
Sbjct: 1927 VPVTPAD------DPIVPVTSADSPIVSV-TPADSPVFPVT 1960
Score = 53.9 bits (128), Expect = 7e-07
Identities = 75/312 (24%), Positives = 103/312 (33%), Gaps = 45/312 (14%)
Query: 349 DSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGP-GPPPCQKAPSGLV 407
D+ GS ++SA P P +P+ + P+ S GP P P V
Sbjct: 714 DTPGSPVTSADG---PVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPV 770
Query: 408 TSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPA 467
TS P S P VP + P P SA P +PA S P PA
Sbjct: 771 TSADGPVAPVSSADGPVVPVT-----PADTNGPAVPVTSADSPFVPVIPADSPVVPVTPA 825
Query: 468 PSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP----------Q 517
P PA S SA +PA S VP P
Sbjct: 826 DDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFAD 885
Query: 518 KAVSPTAPKKKSLL-LPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAV 576
+ V P P ++ + P +P +PT+ +A A +P V P P V
Sbjct: 886 ETVVPLNPADSPVIPVTPPDDLVVPVTPTDCPVAPVTSADCPVVP----VTPADSPADPV 941
Query: 577 LERS----QSGGKPEPVVTVRTQETDVVEMT------TQAKSPESPF-----------TV 615
+P+V V ++ VV +T S +SPF +V
Sbjct: 942 TAADGPVVPFTPADDPIVPVTPADSPVVSVTPADGPVVPVASADSPFVPVTPADDPIVSV 1001
Query: 616 TKKESKDILISQ 627
T ES I ++Q
Sbjct: 1002 TPAESPAIPVTQ 1013
Score = 52.8 bits (125), Expect = 1e-06
Identities = 54/212 (25%), Positives = 74/212 (34%), Gaps = 16/212 (7%)
Query: 402 APSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQK 461
+P+ VT +P + P VP +S P P P S P ++PA+P
Sbjct: 615 SPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQAD 674
Query: 462 APAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP-QKAV 520
+P VP S P IP + + VP P TP + P +P A
Sbjct: 675 SPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSAD 734
Query: 521 SPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERS 580
SP P + P +P + + +A P S D V+P V S
Sbjct: 735 SPFVP------VTPPDGPVVPVTSADGPVA---PVS----SADGPVVPVTSADGPVAPVS 781
Query: 581 QSGGKPEPVVTVRTQETDVVEMTTQAKSPESP 612
+ G PV T V T A SP P
Sbjct: 782 SADGPVVPVTPADTNGPAV--PVTSADSPFVP 811
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/211 (23%), Positives = 69/211 (32%), Gaps = 18/211 (8%)
Query: 359 ASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQ 418
AS +P+ P P S+ A P+ P P VTS P +
Sbjct: 641 ASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVP---------VTSADRPVIPVT 691
Query: 419 SQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAP 478
+ VP ++ P P P + P VP S +P VP P +P
Sbjct: 692 TADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVT 751
Query: 479 SRKASAASASPRKASAVP---APPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKS-----L 530
S A S VP A P S P VP P P P +
Sbjct: 752 SADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAVPVTSADSPFVP 811
Query: 531 LLPAPSQKALPTSPTEYQMALSPPASRGKLP 561
++PA S +P +P + + PA +P
Sbjct: 812 VIPADS-PVVPVTPADDPIVPVTPADSSFVP 841
Score = 51.6 bits (122), Expect = 3e-06
Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 16/213 (7%)
Query: 407 VTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVP 466
VTS +P + + VP ++ P P P + P VP S P VP
Sbjct: 420 VTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADIPLVP 479
Query: 467 APSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVP-TIPQKAVSPTAP 525
P +P S A S VP P +P +P T + P P
Sbjct: 480 VTPPDGPVVPVTSADGPVAPVSSADGPVVPVTP-------ADSPFIPVTTADDLIVPVTP 532
Query: 526 KKKSLLLPAPSQK-ALPTSPTEYQMALSPPASRGKLP---GDFDVLPTGIPGRAVLERSQ 581
+L P++ A+P +P + + PA+ +P D +P V+ +
Sbjct: 533 ADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTP 592
Query: 582 SGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
+ PVV V ++ V+ +T A SP P T
Sbjct: 593 A---DSPVVPVTPADSPVLSVTL-ADSPAVPVT 621
Score = 50.4 bits (119), Expect = 7e-06
Identities = 53/197 (26%), Positives = 68/197 (34%), Gaps = 14/197 (7%)
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKA 482
P VP +S P P P A P P V VP S P +P
Sbjct: 1614 PVVPVTSVDIPVVPVTPANGPVAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADG 1673
Query: 483 SAASASPRKASAVPAPPQKTP---PPSQKAPSVPTIP--QKAVSPTAPKKKSLLLPAPSQ 537
+P + VP P +P S +P +P P V T+ S P S
Sbjct: 1674 LVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVTSA 1733
Query: 538 KALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQET 597
P P +L P + P D V+P V S + G PVV V ++
Sbjct: 1734 DG-PVVPVTSADSLPVPVT----PADGPVVPVTSADGPVAPVSSADG---PVVPVTPADS 1785
Query: 598 DVVEMTTQAKSPESPFT 614
VV +TT A P P T
Sbjct: 1786 PVVPVTT-ADDPTVPVT 1801
Score = 49.7 bits (117), Expect = 1e-05
Identities = 55/201 (27%), Positives = 75/201 (37%), Gaps = 15/201 (7%)
Query: 422 LPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRK 481
+P PA S LA P A PA+PA P PA S P PA
Sbjct: 328 VPVTPADSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPV 387
Query: 482 ASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP-QKAVSPTAP----KKKSLLLPAPS 536
S ASA + VP P P S P +P A SP P + + + A
Sbjct: 388 VSVASAD---SPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAG 444
Query: 537 QKALPTSPTEYQMALSPPASRGKLP---GDFDVLPTGIPGRAVLERSQSGGKPEPVVTVR 593
+P +P + + A +P D ++P P V+ + + G PV V
Sbjct: 445 DPIVPVTPADTPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVPVTSADG---PVAPVS 501
Query: 594 TQETDVVEMTTQAKSPESPFT 614
+ + VV + T A SP P T
Sbjct: 502 SADGPVVPV-TPADSPFIPVT 521
Score = 49.3 bits (116), Expect = 2e-05
Identities = 68/299 (22%), Positives = 99/299 (33%), Gaps = 47/299 (15%)
Query: 355 LSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPF 414
+S A S + P PA + P +P P+ S P P A +V
Sbjct: 2308 VSPADSPVVPVTPA---NIPVVPVPPANGSVVPVTSAGSPFVPIIP-ADGLVVLDSSTDV 2363
Query: 415 LVDQSQKLPAVPASSWKPPPGLA-PPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAP 473
LV +P P ++ +P P +P VP P VP S +P
Sbjct: 2364 LVVLVSPTDGIPVPDLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSP 2423
Query: 474 AIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP-----------QKAVSP 522
+P + +P + VPA P P S P +P A SP
Sbjct: 2424 VVPVTPADSPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVTSADSP 2483
Query: 523 TAP--KKKSLLLPAPSQKA------------LPTSPTEYQMALSPPASRGKL-------- 560
P L++P S + +P P + + L P +
Sbjct: 2484 VVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSP 2543
Query: 561 -----PGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
P D V+P G V+ + G PVV V ++ VV +T+ A SP P T
Sbjct: 2544 VFPVTPADSSVVPVTPAGVPVVPVTPGDG---PVVPVTPADSLVVPVTS-ADSPVFPVT 2598
Score = 45.1 bits (105), Expect = 3e-04
Identities = 40/201 (19%), Positives = 66/201 (32%), Gaps = 13/201 (6%)
Query: 407 VTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVP 466
VT +P + P + +S P P P P +P ++PA+P
Sbjct: 2128 VTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAIP 2187
Query: 467 APSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP-QKAVSPTAP 525
+P +P +P + VP PP P P P A P P
Sbjct: 2188 VTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVP 2247
Query: 526 KKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLP---GDFDVLPTGIPGRAVLERSQS 582
+ + +P +P + + PA P D V P + V + +
Sbjct: 2248 ------VTSADSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPA 2301
Query: 583 GGKPEPVVTVRTQETDVVEMT 603
+P+ V ++ VV +T
Sbjct: 2302 ---DDPIFPVSPADSPVVPVT 2319
Score = 44.7 bits (104), Expect = 4e-04
Identities = 65/231 (28%), Positives = 82/231 (35%), Gaps = 33/231 (14%)
Query: 398 PCQKAPSGLVTSCKAPFLV--DQSQKLPAVPASSWKPPPGLAPPQKA-----PAASAPPR 450
P +A S V A LV D S + VP P G+ P A P A
Sbjct: 41 PVTRAGSPFVPVIPADGLVVLDSSTDVLVVPVF---PADGILVPDFADNPVVPVTPADDL 97
Query: 451 KAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAP 510
P PA S P A P PA + SA+ PA P S P
Sbjct: 98 VFPVTPADSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGP 157
Query: 511 SVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTG 570
VP P A SP P + PA S P +P + + PA +P V P
Sbjct: 158 VVPVTP--ADSPVFP-----VTPADS-PLFPVTPADSPLFPVTPADSAAIP----VTPAD 205
Query: 571 IPGRAVLERSQSGG-------KPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
P V+ + + G PVVTV + ++ VV + T A P P T
Sbjct: 206 GP---VVHVTPANGTVVPVTPADSPVVTVASTDSPVVPV-TPADDPIVPVT 252
Score = 44.7 bits (104), Expect = 4e-04
Identities = 31/129 (24%), Positives = 43/129 (33%), Gaps = 4/129 (3%)
Query: 407 VTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVP 466
VTS P + P P +S P P +P P +P P +P P
Sbjct: 131 VTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFP 190
Query: 467 APSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTP---PPSQKAPSVPTIP-QKAVSP 522
+ AIP +P + VP P +P S +P VP P + P
Sbjct: 191 VTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVP 250
Query: 523 TAPKKKSLL 531
P S +
Sbjct: 251 VTPADSSFV 259
Score = 44.3 bits (103), Expect = 5e-04
Identities = 50/214 (23%), Positives = 74/214 (34%), Gaps = 12/214 (5%)
Query: 407 VTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVP 466
VT P S P VP + P P P P VP +P V
Sbjct: 911 VTPTDCPVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVS 970
Query: 467 APSQKAPAIPAPSRKASAASASPRK---ASAVPAPPQKTPPPSQKAPSVP-TIPQKAVSP 522
P +P S + +P S PA P +P VP T + VSP
Sbjct: 971 VTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSP 1030
Query: 523 -TAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLP---GDFDVLPTGIPGRAVLE 578
T + + + A +P +P + + A +P D +P P V+
Sbjct: 1031 VTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVP 1090
Query: 579 RSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESP 612
+ + G PV V + + VV +T+ A P +P
Sbjct: 1091 VTSADG---PVAPVSSADGPVVPVTS-ADGPVAP 1120
Score = 43.9 bits (102), Expect = 7e-04
Identities = 54/216 (25%), Positives = 73/216 (33%), Gaps = 24/216 (11%)
Query: 422 LPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRK 481
+P PA P A P SA P PA + P A P PA S
Sbjct: 89 VPVTPADDLVFPVTPADSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSPV 148
Query: 482 ASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALP 541
ASA PA P +P P P A SP P + PA S A+P
Sbjct: 149 FPVASADGPVVPVTPADSPVFPVTPADSPLFPVTP--ADSPLFP-----VTPADS-AAIP 200
Query: 542 TSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVE 601
+P + + PA+ +P V P P V PVV V + +V
Sbjct: 201 VTPADGPVVHVTPANGTVVP----VTPADSPVVTV------ASTDSPVVPVTPADDPIVP 250
Query: 602 MT------TQAKSPESPFTVTKKESKDILISQTKEV 631
+T S +SPF +++ + +V
Sbjct: 251 VTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDV 286
Score = 43.1 bits (100), Expect = 0.001
Identities = 63/283 (22%), Positives = 92/283 (32%), Gaps = 33/283 (11%)
Query: 349 DSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVT 408
DS ++SA S L P A P + P G + P+ PG P VT
Sbjct: 1373 DSPVVPVTSADSPLIPLTTAGSRVVPVT--PTG-DPIVPVTPADTPGSP---------VT 1420
Query: 409 SCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAP 468
S P + P VP + P P P VP P VP
Sbjct: 1421 SADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVT 1480
Query: 469 SQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVS------- 521
S P +P + + VP P +P +P +P +
Sbjct: 1481 SADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHVT 1540
Query: 522 -------PTAPKKKSLLLPAPSQ-KALPTSPTEYQMA--LSPPASRGKLPGDFDVLPTGI 571
P P + L + + +P SPT+ + L+ D V+P
Sbjct: 1541 SADCPFVPVIPADGLVALDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTP 1600
Query: 572 PGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFT 614
V+ + + G PVV V + + VV + T A P +P T
Sbjct: 1601 ADSTVVPVTLADG---PVVPVTSVDIPVVPV-TPANGPVAPVT 1639
Score = 42.0 bits (97), Expect = 0.003
Identities = 59/236 (25%), Positives = 73/236 (30%), Gaps = 29/236 (12%)
Query: 355 LSSAASGLAPYPPAACLSTPY----SSIPRGREKAGPMGSHQGPGPP--PCQKAPSGLVT 408
++SA S + P PA C P S I P+ S P P A S +V
Sbjct: 2497 VTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPADSSVVP 2556
Query: 409 SCKA-----PFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAP 463
A P +P PA S P A P A P PA P
Sbjct: 2557 VTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADSPVFPVTPADSPVFPVSPADDLVVP 2616
Query: 464 AVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKA---- 519
P S P PA S A PA P S +P VP IP
Sbjct: 2617 VTPGDSPVVPVSPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPVIPADGLVVL 2676
Query: 520 -------VSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLP 568
V P P L+ +P +P + + P + PGD V+P
Sbjct: 2677 DSSTDVLVVPVFPTDGILVPDLADDPVVPVTPGDDPVV---PVT----PGDDPVIP 2725
Score = 42.0 bits (97), Expect = 0.003
Identities = 57/239 (23%), Positives = 84/239 (35%), Gaps = 33/239 (13%)
Query: 425 VPASSWKPPPGLAPPQKA---PAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRK 481
VPA GL P P S P P VP S P VP P + P +P PS
Sbjct: 2824 VPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPVASADNPGVPDPIRAFPVVPKPSTF 2883
Query: 482 ASAASASPR---KASAVPAPPQKTPPPSQKAPSVPTIPQKA-VSPTAPKKKSLLLPAPSQ 537
+ +++P PA P P VP + V P P ++L P
Sbjct: 2884 SPVVTSTPADWIDVIVTPADCADVPVNPVNGPVVPDLSGDCPVVPVPPTDDIVVLNPPDV 2943
Query: 538 K-ALPTSPTEYQMALSPPASRGKL----PGDFDVLP---------TGIPGRAVLERSQSG 583
A+ ++P ++ PA+ G + P + V P T P + G
Sbjct: 2944 VFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIG 3003
Query: 584 GKPEPVVTVRTQETDVVEMTTQ---------AKSPESPFTVTKKESKDILISQTKEVTL 633
G PVV + ++ VV T P P T T ++++ +VT+
Sbjct: 3004 G---PVVPDPSADSSVVSNPTTDGLIVPNPLLAGPVVPVTPTDGPLAPVILADCPDVTV 3059
Score = 40.8 bits (94), Expect = 0.006
Identities = 54/213 (25%), Positives = 72/213 (33%), Gaps = 32/213 (15%)
Query: 423 PAVPASSWKPPPGLAPPQK------APAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIP 476
P +P + PP L P AP SA P PA S P A P P
Sbjct: 897 PVIPVT---PPDDLVVPVTPTDCPVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTP 953
Query: 477 APSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP--QKAVSPTAPKKKSLLLPA 534
A A S PA P S +P VP P VS T + ++ +
Sbjct: 954 ADDPIVPVTPADSPVVSVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQ 1013
Query: 535 PSQKALPTSPTEYQMALSPPASRGKLP----GD--FDVLPTGIPGRAVLERSQSGGKPEP 588
+P + + ++ A +P GD V P PG V S G P
Sbjct: 1014 ADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPV--TSADG----P 1067
Query: 589 VVTVRTQETDVVEMT---------TQAKSPESP 612
VV V + ++ V +T T A P +P
Sbjct: 1068 VVPVTSADSPFVPVTPPDGPVVPVTSADGPVAP 1100
Score = 40.8 bits (94), Expect = 0.006
Identities = 64/271 (23%), Positives = 84/271 (30%), Gaps = 23/271 (8%)
Query: 349 DSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVT 408
DS ++SA S L P PA + P P S P P +P VT
Sbjct: 1963 DSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPT--DSPVVPVT 2020
Query: 409 SCKAPFL--VDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVP 466
S +P + S +P PA S P + PP P P VP P V
Sbjct: 2021 SADSPVIPVTADSPFVPVTPADS--PVIPVTPPDDL-VVPVTPIDCPVVPVTLVDCPVVS 2077
Query: 467 APSQKAPAIPAPSRKASAASASPRKASAVPAPPQ-----KTPPPSQKAPSVPTIPQKAVS 521
+P P +P + +P P P SV V
Sbjct: 2078 VTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVP 2137
Query: 522 PTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQ 581
T + + + +P +P + + PA +P V P P V
Sbjct: 2138 VTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPVIP----VTPAESPAIPVTPAD- 2192
Query: 582 SGGKPEPVVTVRTQETDVVEMTTQAKSPESP 612
PVV V T D V T A SP P
Sbjct: 2193 -----SPVVPV-TPADDPVVPVTPADSPIVP 2217
Score = 40.4 bits (93), Expect = 0.008
Identities = 42/160 (26%), Positives = 57/160 (35%), Gaps = 15/160 (9%)
Query: 407 VTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPA---ASAPPRKAPAVPAPSQKAP 463
VTS P + P VP +S P P +P ASA P PA S P
Sbjct: 111 VTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFP 170
Query: 464 AVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQK-AVSP 522
PA S P PA S +P ++A+P P P V P V P
Sbjct: 171 VTPADSPLFPVTPADS---PLFPVTPADSAAIPVTP-------ADGPVVHVTPANGTVVP 220
Query: 523 TAPKKKSLLLPAPSQK-ALPTSPTEYQMALSPPASRGKLP 561
P ++ A + +P +P + + PA +P
Sbjct: 221 VTPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVP 260
Score = 39.7 bits (91), Expect = 0.013
Identities = 35/130 (26%), Positives = 43/130 (33%), Gaps = 9/130 (6%)
Query: 396 PPPCQKAPSGLVTSCKAPFLVDQSQK---LPAVPASSWKPPPGLAPPQKAPAASAPPRKA 452
P P + P LV P + D + + PA + P L P + P +
Sbjct: 3157 PDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPVFLTD---CPDVTVTPADS 3213
Query: 453 PAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQK---TPPPSQKA 509
P VP PS P V +P S SP VP P P PS
Sbjct: 3214 PVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPTTDGPVAPDPSVDG 3273
Query: 510 PSVPTIPQKA 519
P VP P A
Sbjct: 3274 PVVPVTPADA 3283
Score = 37.4 bits (85), Expect = 0.065
Identities = 71/308 (23%), Positives = 99/308 (32%), Gaps = 44/308 (14%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQK-APSGLVTSCKAPFLV---DQ 418
+P P P I P+ S GP P +P V S P +
Sbjct: 106 SPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPAD 165
Query: 419 SQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAP 478
S P PA S P A P A P PA PA P PA
Sbjct: 166 SPVFPVTPADSPLFPVTPADSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPAD 225
Query: 479 SRKASAAS-------ASPRKASAVPAPPQKT---PPPSQKAPSVPTIPQKA--------- 519
S + AS +P VP P + P S +P VP IP
Sbjct: 226 SPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTD 285
Query: 520 --VSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKL----PGDFDVLPTGIPG 573
V P P +L+PA + + + + +S + + P D VL +
Sbjct: 286 VLVVPVFP-VNCILVPAFADETIXXXXXXXSLVVSVTTADDPIVPVTPADSPVLSVTLAD 344
Query: 574 RAVLERSQSGG-------KPEPVVTVRTQETDVVEMT------TQAKSPESPFTVTKKES 620
V+ + + PVV V ++ VV +T S +SPF V +
Sbjct: 345 SPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPF-VPVTPA 403
Query: 621 KDILISQT 628
D ++S T
Sbjct: 404 DDPIVSVT 411
Score = 37.4 bits (85), Expect = 0.065
Identities = 46/209 (22%), Positives = 72/209 (34%), Gaps = 34/209 (16%)
Query: 446 SAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAV---------- 495
S P P P + P V P P +P + S +P A V
Sbjct: 3147 SVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPVFLTDCPDV 3206
Query: 496 ---PAPPQKTPPPSQKAPSV-PTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMAL 551
PA P PS P V ++ + P P S++ +P+ + PT
Sbjct: 3207 TVTPADSPVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPTTDGPVA 3266
Query: 552 SPPASRGKL----PGDFDVLPTGI----------PGRAVLERSQSGGKPEPVVTVRTQET 597
P+ G + P D + + P V+ S+ GG PVVT +
Sbjct: 3267 PDPSVDGPVVPVTPADAPTVSVTLADCPDVTVTPPDGLVVSDSKRGG---PVVTGLSTND 3323
Query: 598 DVVEMTTQAKSPESPFTVTKKESKDILIS 626
V+ T + S TVT + +D+ ++
Sbjct: 3324 PVI---TATPADFSDVTVTPADFEDVPVT 3349
Score = 37.0 bits (84), Expect = 0.085
Identities = 36/163 (22%), Positives = 54/163 (33%), Gaps = 3/163 (1%)
Query: 413 PFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKA 472
P D S P VP + P P + P V + P V S
Sbjct: 3264 PVAPDPSVDGPVVPVTPADAPTVSVTLADCPDVTVTPPDGLVVSDSKRGGPVVTGLSTND 3323
Query: 473 PAIPAPSRKASAASASPRKASAVPAPPQKTP--PPSQKAPSVPTIP-QKAVSPTAPKKKS 529
P I A S + +P VP P P P + ++P V + V P P
Sbjct: 3324 PVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDDL 3383
Query: 530 LLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIP 572
++L P + + P + +S P + D V + +P
Sbjct: 3384 VVLEPPDKVPVVPDPISNGLVVSDPITNNTAATDPSVDGSVVP 3426
Score = 35.8 bits (81), Expect = 0.19
Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 34/278 (12%)
Query: 344 TEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAP 403
T+ +D +S A +AP A C + + + P P
Sbjct: 3416 TDPSVDGSVVPVSPADGPVAPVTLADCPDVTITPADDSVVSDSKIRAEFEDVPVTIADCP 3475
Query: 404 SGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAP 463
+ V P + D + P VP PP L P+ PP + P VP P +
Sbjct: 3476 NVPVNPKSGPVVSDLAVDCPVVPIP---PPDDLVAPE-------PPDEVPVVPDPITDSL 3525
Query: 464 AVPAPSQKAPAIPAPS-----------------RKASAASASPRKASAVPAPPQKTPPPS 506
V P P PS + S P ++ VP P S
Sbjct: 3526 VVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSVADVSILPDTSADVPVTPVTLADGS 3585
Query: 507 QKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRG-KLPGDFD 565
S P P V P P ++L + +P + + P + G DF
Sbjct: 3586 VVPDSAPDCP---VVPVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPTTDGPDSIKDFP 3642
Query: 566 VLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMT 603
++P P V+ +++ G PVV + + VV +T
Sbjct: 3643 LVPDPWPDCPVVPVTRTDG---PVVLDSSADGVVVPVT 3677
Score = 34.7 bits (78), Expect = 0.42
Identities = 47/207 (22%), Positives = 65/207 (31%), Gaps = 19/207 (9%)
Query: 374 PYSSIPRGREKAGPMGSHQGPGPP--PCQKAPSGLVTSCKAPFLVDQSQKLPAVPAS--- 428
P + G + P+ P P P P VT P + D + VP S
Sbjct: 2702 PVVPVTPGDDPVVPVTPGDDPVIPVTPADDGPFVPVTPAVGPVVPDLTADDSVVPDSLTD 2761
Query: 429 ----SWKPPPGLAPPQKA-----PAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPS 479
S P GL P P S P P V + P V P + P
Sbjct: 2762 DPVISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSAADCPVVSVPLTDGLVVLCPP 2821
Query: 480 RKASAASASPRKASAVPAPPQKTP---PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPS 536
+ A S VP P P PS P VP P + ++P PS
Sbjct: 2822 DEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPVASADNPGVPDPIRAFPVVPKPS 2881
Query: 537 --QKALPTSPTEYQMALSPPASRGKLP 561
+ ++P ++ + PA +P
Sbjct: 2882 TFSPVVTSTPADWIDVIVTPADCADVP 2908
Score = 34.3 bits (77), Expect = 0.55
Identities = 55/230 (23%), Positives = 78/230 (33%), Gaps = 35/230 (15%)
Query: 398 PCQKAPSGLVTSCKAPFLVDQSQKL--PAVPASSWKPPPGLAP------------PQKAP 443
P A S +V++ L+ + L P VP + P LAP P P
Sbjct: 3008 PDPSADSSVVSNPTTDGLIVPNPLLAGPVVPVTPTDGP--LAPVILADCPDVTVTPADGP 3065
Query: 444 AASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTP 503
A P P P+ + V P+ P + PS K SA+P + VP P P
Sbjct: 3066 VVCAFTTGGPVFPDPTAEGLVVSNPTVDDPVVTNPSTK-GLVSATPADCADVPVIPADCP 3124
Query: 504 PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGD 563
+ +P T + + P P P E + L P D
Sbjct: 3125 DVLVNLVNDSVVPDFTADWTV-----VSVSPPDDLVAPDPPDEVPVVLVPIT-------D 3172
Query: 564 FDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMT-TQAKSPESP 612
V+P V+ + +G PV TD ++T T A SP P
Sbjct: 3173 GPVVPDLTTDGLVVSVTPAGAPVVPVFL-----TDCPDVTVTPADSPVVP 3217
Score = 33.5 bits (75), Expect = 0.94
Identities = 31/123 (25%), Positives = 37/123 (30%), Gaps = 4/123 (3%)
Query: 398 PCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPA 457
P P V S P + D + P VP S P + P P VP
Sbjct: 2850 PSVDGPIVPVASADNPGVPDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCADVPV 2909
Query: 458 PSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPP----PSQKAPSVP 513
P VP S P +P P P AV + P P P+ VP
Sbjct: 2910 NPVNGPVVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVP 2969
Query: 514 TIP 516
P
Sbjct: 2970 VTP 2972
Score = 32.0 bits (71), Expect = 2.7
Identities = 52/248 (20%), Positives = 76/248 (30%), Gaps = 28/248 (11%)
Query: 435 GLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASA 494
G+ P A P P + P VP P P +P S
Sbjct: 3614 GVVVPNPADVGPVVPDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVV 3673
Query: 495 VPAPPQK------TPPPSQKAPSVPTIPQKAVSPTA-------PKKKSLLLPAPSQK--A 539
VP P TP + P + T P+A LL+P P K
Sbjct: 3674 VPVTPGDDSVALVTPTDNLVVPDLTTDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTV 3733
Query: 540 LPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGK--PEP----VVTVR 593
+P S + +AL P D ++P V+ S G P+P V +
Sbjct: 3734 VPNSVADNPVALDPVT-------DCPLVPEPSANGLVVTDSLDEGPVVPDPSADDPVVLN 3786
Query: 594 TQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEE 653
+ +V A P P T T + EV + A G + D + +
Sbjct: 3787 PETNGLVVPDISANGPVVPDTPTDGSDATVTPDDCSEVFVTATDGPDVVSDCPIVPETSD 3846
Query: 654 RSPDLPGV 661
+PG+
Sbjct: 3847 DDLIVPGI 3854
Score = 31.6 bits (70), Expect = 3.6
Identities = 46/188 (24%), Positives = 59/188 (31%), Gaps = 31/188 (16%)
Query: 351 GGSTLSSAASGLA----PYPPAACLSTPYSSIPRGREKAGPMGSHQGPG-PPPCQKAPSG 405
G L S+A G+ P + L TP ++ P + GP P P P
Sbjct: 3661 GPVVLDSSADGVVVPVTPGDDSVALVTPTDNL------VVPDLTTDGPVVPDPSADGPVV 3714
Query: 406 LVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPR----------KAPAV 455
LV+ + + K VP S P L P P P + P V
Sbjct: 3715 LVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTDCPLVPEPSANGLVVTDSLDEGPVV 3774
Query: 456 PAPSQKAPAVPAP----------SQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPP 505
P PS P V P S P +P S A+ +P S V P
Sbjct: 3775 PDPSADDPVVLNPETNGLVVPDISANGPVVPDTPTDGSDATVTPDDCSEVFVTATDGPDV 3834
Query: 506 SQKAPSVP 513
P VP
Sbjct: 3835 VSDCPIVP 3842
Score = 31.2 bits (69), Expect = 4.6
Identities = 59/258 (22%), Positives = 85/258 (32%), Gaps = 50/258 (19%)
Query: 416 VDQSQKLPAVPASSWKPPPGLA-------PPQKAPAASAPPRKAPAVPAPSQKAPAVPAP 468
+D +P PA P A P P A P P VP AP V
Sbjct: 3230 LDDDGLVPVTPADDSVVPDSPANGLVVPDPTTDGPVAPDPSVDGPVVPVTPADAPTVSVT 3289
Query: 469 SQKAPAIPAPSRKASAASASPRKA-------------SAVPA---PPQKTPPPSQKAPSV 512
P + S S R +A PA TP + P
Sbjct: 3290 LADCPDVTVTPPDGLVVSDSKRGGPVVTGLSTNDPVITATPADFSDVTVTPADFEDVPVT 3349
Query: 513 P-TIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGI 571
P P V+P +P L A +P P++ + L PP K+P V+P I
Sbjct: 3350 PANCPDVPVNPESPVVSDL---AVDFLVVPVVPSDDLVVLEPP---DKVP----VVPDPI 3399
Query: 572 PGRAVLERSQSGGKPEPVVTVRTQETD-----VVEMTTQAKSPESPFTVTKKESKDILIS 626
V+ +P +T T TD V + A P +P VT + D+ I+
Sbjct: 3400 SNGLVVS--------DP-ITNNTAATDPSVDGSVVPVSPADGPVAP--VTLADCPDVTIT 3448
Query: 627 QTKEVTLEAFRGQGKLED 644
+ + + + + ED
Sbjct: 3449 PADDSVVSDSKIRAEFED 3466
Score = 31.2 bits (69), Expect = 4.6
Identities = 32/133 (24%), Positives = 39/133 (29%), Gaps = 27/133 (20%)
Query: 448 PPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAP----PQKTP 503
PP K P VP P V P A PS S SP P P T
Sbjct: 3388 PPDKVPVVPDPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLADCPDVTI 3447
Query: 504 PPSQKA---------------------PSVPTIPQK--AVSPTAPKKKSLLLPAPSQKAL 540
P+ + P+VP P+ VS A + +P P
Sbjct: 3448 TPADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVA 3507
Query: 541 PTSPTEYQMALSP 553
P P E + P
Sbjct: 3508 PEPPDEVPVVPDP 3520
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 70.9 bits (172), Expect = 5e-12
Identities = 82/291 (28%), Positives = 104/291 (35%), Gaps = 40/291 (13%)
Query: 350 SGGSTLSSAASGLAPYPPAAC-----LSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPS 404
S + L S A P P + L+TP P + P P PP PS
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS--PSAPPSLQTLPSPPATP--PS 363
Query: 405 GLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPA 464
TS +P L LP+ P S PP PQ PA + PP +AP P S
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAPPALALPPLQAPPSPPASPPLSP 419
Query: 465 VPAPSQKAPAI-------------PAPSRKA--SAASASPRKASAVP---APPQKTPPPS 506
+ PS +AP P+P +A S ++ P SA P APP PP
Sbjct: 420 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 479
Query: 507 QKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDV 566
Q PS P P + S T P + L AP + P +PP P
Sbjct: 480 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP----- 534
Query: 567 LPTGIPGRAVLERSQSGGKP-EPVVTVRTQETDVVEMTTQAKSPESPFTVT 616
P PG+A S S P P+ T Q V+ P P + T
Sbjct: 535 -PASFPGQAPF--SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582
Score = 61.2 bits (147), Expect = 4e-09
Identities = 64/210 (30%), Positives = 81/210 (38%), Gaps = 25/210 (11%)
Query: 366 PPAACLSTPYSSIPRGRE--------KAGPMGSHQGPGPPPCQK--APSGLVTSCKAPFL 415
PP + L+TP P P Q P PP +PS S P L
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474
Query: 416 VDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAI 475
++P P +S P PP +AP A P A P P Q PA+ P P
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP-PPQAPPALATP----PLQ 529
Query: 476 PAPSRKASAASASPRKASA-VPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLP- 533
PS AS +P SA +P P TPPP +AP V P V P+ P +L P
Sbjct: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPP--QAPPVLAAPLLQVPPSPPASPTLQAPR 587
Query: 534 APSQKALPTSPTEYQMALS------PPASR 557
P TS + ++ L+ PP SR
Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617
Score = 55.8 bits (133), Expect = 2e-07
Identities = 72/278 (25%), Positives = 106/278 (38%), Gaps = 33/278 (11%)
Query: 355 LSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGP---GPPPCQKAPSGLVTSC- 410
+S +A+ + PP+ L+ P +P + PM P PPP P L
Sbjct: 460 VSPSATPPSQAPPS--LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 411 KAP--FLVDQSQKLPAVPASSWKPPPGLAPPQKA------PAASAPPRKAPAVPAPSQKA 462
+AP Q LP+ PAS PG AP + P A+ PP+ P + AP +
Sbjct: 518 QAPPALATPPLQALPSPPASF----PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573
Query: 463 PAVPAPSQ-----KAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQ 517
P P S + P P P S + A P PP ++P + P +
Sbjct: 574 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 633
Query: 518 KAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPA--SRGKLPGDFDVLPTGIPGRA 575
A S P++ P A + P + ++A PA SRG P + G PG
Sbjct: 634 SATS--TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP---PLAFRGAPGAP 688
Query: 576 VLERSQSG-GKPEPVVTVRTQETDVVEMTTQAKSPESP 612
+ +G G + + T+ ET+ E T A P
Sbjct: 689 LPWPPATGPGSADGLCTI--YETEGPESATPAPGALDP 724
Score = 52.0 bits (123), Expect = 3e-06
Identities = 75/282 (26%), Positives = 99/282 (35%), Gaps = 43/282 (15%)
Query: 287 TANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTED 346
T+ T +P + A G + P+ P G S+ H TE
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE---GPRKSVSSASEHSTTEP 220
Query: 347 LMDSGGSTLSSAASGLAPYPPAACLS---TPYSSIPRGREKAGPMGSHQGPGPPPCQKAP 403
S + +A G P + LS TP SS R A G+ + P P Q P
Sbjct: 221 ---SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA--RGTPRAPAHPS-QPKP 274
Query: 404 SGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAP 463
GL Q+ + P V P L P +P A+ P A AP P
Sbjct: 275 KGL-----------QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT-LP 322
Query: 464 AVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPT 523
A P S + P A + ++P +P+PP PPSQ S+ SPT
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP--ATPPSQATTSLG-------SPT 373
Query: 524 APKKKSLLLPAPSQKALPTSPTEYQMAL---------SPPAS 556
S LP+P L T P + AL SPPAS
Sbjct: 374 LQATHS-FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414
Score = 51.6 bits (122), Expect = 3e-06
Identities = 110/490 (22%), Positives = 168/490 (34%), Gaps = 69/490 (14%)
Query: 426 PASSWKPPPGLAPP--QKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKAS 483
P S +PPP + P + AA A RK A A +P + +A P+R A
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA----GPTRSAG 84
Query: 484 AASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAP---KKKSLLLPAPSQKAL 540
+S +P ++ PP +P + P +A T P +K L + A A
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 541 -PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGK----PEPVVTVR-- 593
+ + ALS A R D G P A+ RS++ G P P + R
Sbjct: 145 GKATEAPKRSALSAGARR-----DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 594 ------------TQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRG--- 638
E E + A+ S ++ + L S ++ A G
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 639 QGKLEDWAHWAK-----LEERSPDLPGVRSKELEQRKRWVKAKELAVEGPS------QEH 687
+G AH ++ L+ P K+ + + LA PS
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP 319
Query: 688 SRPFSVEALTLTKLMITANSKEQPSKSA---LVSLPSWLLATPQASATSMMASVPSRPGQ 744
+ P + + +LT + T PS SA L +LPS ATP + AT+ + S P+
Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPATPPSQATTSLGS-PTLQAT 377
Query: 745 LSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTS 804
S L P+ P P ++ PP P PP P +
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPP-----------LQAPPSPPASPPLSPLATPSPQ 426
Query: 805 A------SLKREGISQAPIPLTASPWEDLRPSPLSETLISKMEATARASQQPKRVSQEPM 858
A L + S P P +P+ P+S + +A + P +V P
Sbjct: 427 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486
Query: 859 RMPAQHPLAT 868
P P AT
Sbjct: 487 ASPPMSPSAT 496
Score = 51.2 bits (121), Expect = 4e-06
Identities = 123/563 (21%), Positives = 187/563 (33%), Gaps = 95/563 (16%)
Query: 351 GGSTLSSAASGLAPYPPAACLSTPYSSIP--RGREKAGPMGSHQGPGPP----------- 397
GG+T+ +A P A S +S P GR + P + PGP
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 398 PCQKAPSGLVTSCKAPFLVDQSQKLP---AVPASSWK----PPPGLAPPQKAPAASAP-- 448
P GL S + ++ + P A+ A + + P PG P A + A
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 449 ----PRKAPAV-PAPSQKAP--AVPAPSQKAPAIPAPS--RKASAASASPRKAS-AVPAP 498
PR AP+ P P + P +V + S+ + P+P+ R+ SA R AS ++ +
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 499 PQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRG 558
P++ PS P+ P+ PK K L P Q P + AL P +S
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK--DAAPALGPLSSS- 302
Query: 559 KLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKK 618
P P + +SQ+ P T + + P +P + +
Sbjct: 303 ---------PLATPSPSAALQSQA-----PPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348
Query: 619 ESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVKAKEL 678
S L S +A G SP L S ++ + L
Sbjct: 349 PSLQTLPSPPATPPSQATTSLG--------------SPTLQATHS--------FLPSPPL 386
Query: 679 AVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASV 738
+ + P AL L L + P S L ATP A + +A V
Sbjct: 387 SPLATPPPQAPP----ALALPPLQAPPSPPASPPLSPL--------ATPSPQAPNALA-V 433
Query: 739 PSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGE-MKEPPWDPKGPPKVP 797
S PV P + V P + ++ PP P PP P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 798 FRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKMEATARASQQPKRVSQEP 857
+ P QAP PL A P + +P P + ++ A S Q P
Sbjct: 494 SATPPP----------QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543
Query: 858 MRMPAQHPLATVGSSSEILLPML 880
A P++ + + P+L
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVL 566
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 67.8 bits (164), Expect = 4e-11
Identities = 122/562 (21%), Positives = 199/562 (35%), Gaps = 91/562 (16%)
Query: 362 LAPYPPAACLSTPYSSIPRGRE------KAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFL 415
L+P P A+ LS P+ P P S P P +P + P
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP-- 593
Query: 416 VDQSQKLPAVPASSWKPPPG---LAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKA 472
+ S+ P S PPP L+PP +A S PP +P P P + + P +
Sbjct: 594 PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653
Query: 473 PAIPAPSRKA-------------SAASASPRKASAVPAPPQKTP--PPSQKAPSVPTIPQ 517
+P SR + + ++ P +AS + PP+ +P PP + +P+ P P
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP--PP 711
Query: 518 KAVSPTAPKKKSLLLPAPSQKAL----------------PTSPTEYQMALSPPASRGKL- 560
+ + P ++S LLP P + L SP + LSP A L
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLS 771
Query: 561 PGDFDVLPTGIPGRAVLERSQSGG--KPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKK 618
P + +P L G P+P + +T+ + + PE P ++ +
Sbjct: 772 PQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHL---SPVPEEP-CLSPQ 827
Query: 619 ESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVKAKEL 678
+ L Q++E L + L E P L K E+ + +EL
Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSP-------ELEKPPLSPRPEKPPEEPGQCPAPEEL 880
Query: 679 AVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASV 738
+ P E S ++ + +P + L LP L +P + +
Sbjct: 881 PLFPPPGEPS----------LSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 739 PSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPF 798
P P L P++ P + + P GE+ E P+G + DP+ P P
Sbjct: 931 PPDPLPPPL---SPIITAAAPPALS-------PLGEL-EYPFGAKGDS--DPESPLAAPI 977
Query: 799 RSKPTSASLKREGISQAPIP---LTASPWEDLRPSP--LSETLISKMEATARAS-----Q 848
P S + P+P L SP + P+ L E L + + S
Sbjct: 978 LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS 1037
Query: 849 QPKRVSQEPMRMPAQHPLATVG 870
P + S + + PL+ +G
Sbjct: 1038 PPSQCSPPALPLSVPSPLSPIG 1059
Score = 61.2 bits (147), Expect = 4e-09
Identities = 143/587 (24%), Positives = 214/587 (36%), Gaps = 113/587 (19%)
Query: 351 GGSTLSSAASGLAP----YPPAACLSTPYSSIP------RGREKAGPMGSHQG--PGPPP 398
GG T+ S A P + P TP +G+ K G + S Q PGP
Sbjct: 354 GGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQ 413
Query: 399 CQKAPSG-----LVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAP-------------PQ 440
C+ P G L +AP L ++ LP S PPP +P P+
Sbjct: 414 CEAKPLGKAGVQLEPQLEAP-LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPE 472
Query: 441 KAPAA-----------------SAPPRKAPAVP-------APSQKAP-AVPAPSQKAPAI 475
+ PA+ S PP ++P P +P +++P + P S +PA+
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPAL 532
Query: 476 PAPSRKASAAS--ASPRKASAVPAPPQKTP-----------PPSQKAPSVPTIPQKAVSP 522
P AS + P + S + PP++ P PP +++P P + +SP
Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Query: 523 TAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKL---PGDFDVLPTGIPGRAVLER 579
P + S L P P +++ P SP + LSPP +L P D + P
Sbjct: 593 --PPEASRLFP-PFEES-PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
Query: 580 SQSGGKPEPVVTVRTQETDVVEMT-TQAKSPESPFTVTKKESKDILISQTKEVTLEAFRG 638
S P PVV+ + + ++ +SP SP + S S T E
Sbjct: 649 EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP-EDSPA 707
Query: 639 QGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSVEALTL 698
ED LEE SP LP +L R + L+ P + H P E L
Sbjct: 708 SPPPEDSLMSLPLEE-SPLLPLPEEPQLCPRS---EGPHLSPR-PEEPHLSP-RPEEPHL 761
Query: 699 TKLMITANSKEQPSKSALVSLPSWLLATPQASATSM-----------------MASVPSR 741
+ + QP + L ++P +PQA + ++ VP
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Query: 742 P--------GQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMKEPPWDPKGP 793
P LS +P + ESH + K P E+P E + P P+
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCP-APEEL 880
Query: 794 PKVPFRSKPTSASLKREGISQAP--IPLTASPWEDLRPSPLSETLIS 838
P P +P+ + L E P PL+ P E+L SP E +S
Sbjct: 881 PLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP-EELPLSPSGEPSLS 926
Score = 47.8 bits (112), Expect = 5e-05
Identities = 113/452 (25%), Positives = 145/452 (32%), Gaps = 116/452 (25%)
Query: 438 PPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQ----KAPA--IPAPSRKASAASASPRK 491
PPQ S PP AP + S PA + S K PA +P P P
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP-- 2164
Query: 492 ASAVPAPPQKTP--PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQM 549
P P + P P AP+ P P+ PTAP P PS P P
Sbjct: 2165 ----PQVPAQVPSQDPFGLAPAYPLEPR---FPTAPPTYP---PYPSPTGAPAQPPMLGA 2214
Query: 550 ALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSP 609
+ P A + PG+F P G P P+P + R D + + P
Sbjct: 2215 SSRPGAGQ---PGEFHTTPPGTP-------RHQPSTPDPFLKPRCPSLDNLAV------P 2258
Query: 610 ESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQR 669
ESP K S+ +L SP G K LE
Sbjct: 2259 ESPGVGGGKASEPLL------------------------------SPPPFGESRKALE-- 2286
Query: 670 KRWVKAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATP-- 727
VK +EL PS + P N S S+ L L TP
Sbjct: 2287 ---VKKEELGASSPS--YGPP---------------NLGFVDSPSSGTHLGGLELKTPDV 2326
Query: 728 -QASATSMMASV-PSRPGQLSLLEGKP---VVVREQPESHTWVKEGKRPWGEMKEQPWGE 782
+A T + V P PG L L +P + P SH + + P
Sbjct: 2327 FKAPLTPRASQVEPQSPG-LGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP 2385
Query: 783 MKEPP-------WDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSET 835
+PP P+ P PF P AS + + SQ+P L P PLS
Sbjct: 2386 RPQPPPPESCCALPPRSLPSDPFSRVP--ASPQSQSSSQSP----------LTPRPLSAE 2433
Query: 836 LISKMEATARASQQPKRVSQEPMRMPAQHPLA 867
T R Q P S+ P R ++ P A
Sbjct: 2434 AFCPSPVTPR-FQSPDPYSRPPSRPQSRDPFA 2464
Score = 46.2 bits (108), Expect = 1e-04
Identities = 75/334 (22%), Positives = 108/334 (32%), Gaps = 50/334 (14%)
Query: 249 PAEKKSHSDPRPDRTHTQIRL--------PEKTSITTWTIFSIISSTANQTQSSPKACTS 300
P ++ H PRP+ H + PE+ + +S A SP+
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL 804
Query: 301 ASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTED-LMDSGGSTLSSAA 359
T + H+ P + P+ L S S +PCL + E L S
Sbjct: 805 HLSPQTEEPHLSPVPEEPCLSPQPEESHL-SPQSEEPCLSPRPEESHLSPELEKPPLSPR 863
Query: 360 SGLAPYPPAACLSTPYSSI--PRGREKAGPMGSHQG---PGPPPCQKAPSGLVTSCKAPF 414
P P C + + P G P+ PG PP P
Sbjct: 864 PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP----------- 912
Query: 415 LVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPS----------QKAPA 464
++LP P+ P L PP P +P A A PA S K +
Sbjct: 913 -----EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDS 967
Query: 465 VPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPP--SQKAPSVPTIPQKAVSP 522
P AP + P A+ + + P PP PP S P+ P + +
Sbjct: 968 DPESPLAAPILETPISPPPEANCTDPE----PVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Query: 523 TAPKKKSLLLP---APSQKALPTSPTEYQMALSP 553
+P + L+P PSQ + P P LSP
Sbjct: 1024 CSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP 1057
Score = 39.7 bits (91), Expect = 0.013
Identities = 47/198 (23%), Positives = 73/198 (36%), Gaps = 28/198 (14%)
Query: 388 MGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVP-ASSWKPPPGLAPPQKAPAAS 446
+G GP P Q+ +G + P +LPA P A S P G P P++
Sbjct: 4263 LGGFPGPQTGPLQELGAG--PRPQGP------PRLPAPPGALSTGPVLGPVHPTPPPSSP 4314
Query: 447 APPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPS 506
P++ +P+PS + +P +Q P P + K + P PA Q
Sbjct: 4315 QEPKRPSQLPSPSSQ---LPTEAQLPPTHPG-TPKPQGPTLEPPPGRVSPAAAQLADTLF 4370
Query: 507 QKAPSVPTIPQKAVSPTAPKKKSL-----------LLPAPSQKALPTSPTEYQMALSPPA 555
K P P++ SL ++P SQ ++ P E AL +
Sbjct: 4371 SKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQS 4430
Query: 556 SRGKLPGDFDVLPTGIPG 573
+ + G+ P G PG
Sbjct: 4431 VKREANGE----PIGAPG 4444
Score = 38.1 bits (87), Expect = 0.038
Identities = 42/169 (24%), Positives = 57/169 (33%), Gaps = 45/169 (26%)
Query: 432 PPPGLAPPQKAPAASAPPRKAPAVP----APSQKAPAVPAPSQKAPAIPAPSRKASAASA 487
P PG P Q+ ++A A A S + P+ P P A+ +P S
Sbjct: 2803 PYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLP 2862
Query: 488 SPRKASAVPAPPQK----------------TPPPSQKAPSVPTI---------------- 515
P + PA P + TP P Q P P
Sbjct: 2863 GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLR 2922
Query: 516 --------PQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPAS 556
PQK +P AP+ + L P P K PT PT ++ PP+S
Sbjct: 2923 GLAVSGLPPQKPSAPPAPELNNSLHPTPHTKG-PTLPTGLELVNRPPSS 2970
Score = 36.6 bits (83), Expect = 0.11
Identities = 76/331 (22%), Positives = 100/331 (30%), Gaps = 74/331 (22%)
Query: 366 PPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAV 425
PP P S P G A P+ PP PS + P L S+
Sbjct: 2164 PPQVPAQVP-SQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQ 2222
Query: 426 PASSWKPPPGLAPPQKAPAASAP---PR----------KAPAVPAPSQKAPAVPAP---- 468
P PPG P+ P+ P PR ++P V P + P
Sbjct: 2223 PGEFHTTPPG--TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 469 SQKAPAIPAPSRKASAASASPRKASAVPAPPQ------------------KTPPPSQKAP 510
S+KA + AS+ S P V +P TP SQ P
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP 2340
Query: 511 SVPTI--------PQKAVSPTAPKKKSLLLPA--------PSQKALPTSPTEYQMALSPP 554
P + P +A++P+ P + P P P P PP
Sbjct: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400
Query: 555 ASRGKLPGD-FDVLPTGIPGRAVLERSQSGGKPEPV---------VTVRTQETDVVEMTT 604
S LP D F +P ++ SQS P P+ VT R Q D
Sbjct: 2401 RS---LPSDPFSRVPASPQSQS---SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454
Query: 605 QAKSPESPFTVTKKESKDILISQTKEVTLEA 635
PF K + Q EV +A
Sbjct: 2455 SRPQSRDPFAPLHKPPR----PQPPEVAFKA 2481
Score = 35.4 bits (80), Expect = 0.25
Identities = 71/325 (21%), Positives = 99/325 (30%), Gaps = 44/325 (13%)
Query: 249 PAEKKSHSDPRPDRTHT--QIRLPEKTSITTWTIFSIISSTANQTQSSPKACTSASDEAT 306
P + H P+P+ H Q P + + S ++ + S + C S E +
Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEES 849
Query: 307 GQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYP 366
+E P + P G C + + + S L A P
Sbjct: 850 HLSPELEKPPLSPRPEKPPEE-PGQCPAPEELPLFPPPGE--PSLSPLLGEPALSEPGEP 906
Query: 367 PAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQ-KLPAV 425
P + L P G P P PPP S ++T+ P L + + P
Sbjct: 907 PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPL----SPIITAAAPPALSPLGELEYPFG 962
Query: 426 PASSWKPPPGLAPPQKAPAASAPPRK--------APAVPAPSQKAPAVPA-PSQKAPAIP 476
P LA P S PP P + PS +P PA P P P
Sbjct: 963 AKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP 1022
Query: 477 APS---RKASAASASPRKASAVPAPPQKTPPP----------SQKA------------PS 511
S + + SP + PA P P P S +A P
Sbjct: 1023 QCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE 1082
Query: 512 VPTIPQKAVSPTAPKKKSLLLPAPS 536
P + A SP L PAPS
Sbjct: 1083 CPALEPSATSPLPSPMGDLSCPAPS 1107
Score = 35.4 bits (80), Expect = 0.25
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 12/92 (13%)
Query: 470 QKAPAIPAPSRKASAASASPRKASAVPAPP--QKTPPPSQKAPSVPTIPQKAVSPTAPKK 527
Q++PA P++ + + S + APP + +PPPS AP SP +P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAP----------SPASPPT 4930
Query: 528 KSLLLPAPSQKALPTSPTEYQMALSPPASRGK 559
+ L+ A P P+ +A SP ++R K
Sbjct: 4931 EPLVELPTEPLAEPPVPSPLPLASSPESARPK 4962
Score = 34.3 bits (77), Expect = 0.55
Identities = 46/180 (25%), Positives = 60/180 (33%), Gaps = 30/180 (16%)
Query: 351 GGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPP--PCQKAPSGLVT 408
GG L + AP P A P S R + P P PP P P
Sbjct: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376
Query: 409 SCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAP 468
P L + Q PP + PPR P+ P + PA P
Sbjct: 2377 PYAQPPLTPRPQ-----------------PPPPESCCALPPRSLPS--DPFSRVPASP-Q 2416
Query: 469 SQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKK 528
SQ + P R SA + P + P ++P P + PS P ++ P AP K
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVT----PRFQSPDPYSRPPSRP----QSRDPFAPLHK 2468
Score = 33.9 bits (76), Expect = 0.72
Identities = 47/156 (30%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 401 KAPSGLVTSCKAP---FLVDQSQKLPAVPASSWKPPPGLAP--PQKAPAASAPPRKAPAV 455
K P+G V +P FL Q VP+ P GLAP P + +APP P
Sbjct: 2144 KPPAGSVPGPDSPGELFLKLPPQVPAQVPSQD---PFGLAPAYPLEPRFPTAPPTYPP-Y 2199
Query: 456 PAPSQKAPAVPAP--SQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVP 513
P+P+ APA P + P P + +PR + P P K PS +VP
Sbjct: 2200 PSPTG-APAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVP 2258
Query: 514 TIPQKAVSPTAPKKKSLLLPAP---SQKALPTSPTE 546
P + + LL P P S+KAL E
Sbjct: 2259 ESPGVGGGKAS---EPLLSPPPFGESRKALEVKKEE 2291
Score = 33.9 bits (76), Expect = 0.72
Identities = 71/285 (24%), Positives = 97/285 (34%), Gaps = 50/285 (17%)
Query: 331 SCSSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAA---CLS---------TPYS-- 376
SC +L P D + + + SS+ S L P P +A C S PYS
Sbjct: 2394 SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453
Query: 377 -SIPRGREKAGPMGSHQGPGPPPCQ---KAPSGLVTSCKAPFLVDQSQKLPAVPAS---- 428
S P+ R+ P+ H+ P P P + KA S TS A LPA PA
Sbjct: 2454 PSRPQSRDPFAPL--HKPPRPQPPEVAFKAGSLAHTSLGAGGF---PAALPAGPAGELHA 2508
Query: 429 ---SWKPPPGLAPPQKA-------------PAASAPPRKAPAVPAPSQKAP-AVPAPSQK 471
S +PP + P P A P P VP P P + +
Sbjct: 2509 KVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGP 2568
Query: 472 APAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPK-KKSL 530
P + P + S P P S P P + P AP
Sbjct: 2569 GPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLS-PLRPPSVLPPPAPDGSLPY 2627
Query: 531 LLPAPSQKALPTSPTEYQ----MALSPPASRGKLPGDFDVLPTGI 571
L SQ++ TSP E + + + +LPG D +G+
Sbjct: 2628 LSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGL 2672
Score = 33.5 bits (75), Expect = 0.94
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 437 APPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKA--PAIPAPSRKASA-ASASPRKAS 493
APP + P S PP PA P V P++ P +P+P AS+ SA P+ +
Sbjct: 4908 APPPEEP--SPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
Query: 494 AVPAPPQKTPPPSQK 508
P + + PP K
Sbjct: 4966 RPPEEGEDSRPPRLK 4980
Score = 30.4 bits (67), Expect = 7.9
Identities = 35/148 (23%), Positives = 50/148 (33%), Gaps = 20/148 (13%)
Query: 368 AACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPA 427
A L TP S P + P PP G +P L++ P P
Sbjct: 975 APILETPISPPPEAN------CTDPEPVPPMILPPSPGSPVGPASPILME-----PLPPQ 1023
Query: 428 SSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKAS---A 484
S L P P+ +PP +VP+P V S +A + K S
Sbjct: 1024 CSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPEC 1083
Query: 485 ASASPRKASAVPAP------PQKTPPPS 506
+ P S +P+P P +P P+
Sbjct: 1084 PALEPSATSPLPSPMGDLSCPAPSPAPA 1111
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 67.8 bits (164), Expect = 4e-11
Identities = 57/177 (32%), Positives = 72/177 (40%), Gaps = 27/177 (15%)
Query: 369 ACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPAS 428
A L Y R A +G PP +AP G PA A+
Sbjct: 81 AVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGA----------------PAAAAA 124
Query: 429 SWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAI--PAPSRKASAAS 486
+ PP PP AP A+A P +AP A + AP P P+Q P AP A
Sbjct: 125 AAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAP 184
Query: 487 ASPRKASAVPAPPQKTPPPSQKA--PSVPTIPQKAVSPTAPKKKSLLLPAPSQKALP 541
A+P A A PA P++ PPP+ A P +P PQ P AP ++ P P Q P
Sbjct: 185 AAP-PAVAPPAGPRRAPPPAVAAREPPLPPPPQ----PPAPPQQQ--QPPPPQPQPP 234
Score = 60.5 bits (145), Expect = 7e-09
Identities = 50/161 (31%), Positives = 67/161 (41%), Gaps = 18/161 (11%)
Query: 427 ASSWKPPPGLAPPQKAPAA--SAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASA 484
A+ +PP A P P A AP A A P P+ P PAP A AP A+A
Sbjct: 96 AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155
Query: 485 ASASPRKASAVPAP------PQKTPPPSQKAP---SVPTIPQKAVSPTAPKKKSLLLPAP 535
A+A P A P P P PPP+ AP + P P++A P ++ L P P
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215
Query: 536 SQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAV 576
P +P + Q PP + + P + + G R V
Sbjct: 216 Q----PPAPPQQQ---QPPPPQPQPPPEGGAVRAGGAARPV 249
Score = 51.6 bits (122), Expect = 3e-06
Identities = 46/148 (31%), Positives = 59/148 (39%), Gaps = 27/148 (18%)
Query: 364 PYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLP 423
P PP A PRG A + PP AP +AP + P
Sbjct: 109 PAPPRA---------PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159
Query: 424 AVPASSWKPP------PGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPA 477
P + P P APP PA +APP AP PA ++AP PA + + P +P
Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPP---PAPAAPPAVAP--PAGPRRAPP-PAVAAREPPLPP 213
Query: 478 PSRKASAASASPRKASAVPAPPQKTPPP 505
P + A P++ P PPQ PPP
Sbjct: 214 PPQ----PPAPPQQQQ--PPPPQPQPPP 235
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 20/128 (15%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKL 422
AP PP A ++ ++ P +A + P P P Q P AP
Sbjct: 132 APPPPPAPVA---AAAPARAPRAAAAAATAPPSPGPAQPGPRA---QRAAPLAAP----- 180
Query: 423 PAVPASSWKPPPGLAPP---QKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPS 479
P PA+ PP +APP ++AP + R+ P P P + PA P Q P P P
Sbjct: 181 PPAPAA----PPAVAPPAGPRRAPPPAVAAREPPLPPPP--QPPAPPQQQQPPPPQPQPP 234
Query: 480 RKASAASA 487
+ A A
Sbjct: 235 PEGGAVRA 242
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 67.4 bits (163), Expect = 6e-11
Identities = 91/320 (28%), Positives = 117/320 (36%), Gaps = 68/320 (21%)
Query: 358 AASGLAPYPPAACLSTPYSSIPRGREK-AGPM------------GSHQGPGPPPCQKAPS 404
+A AP P AA ++ P G K AGP G GPGP P + A
Sbjct: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP 192
Query: 405 GLV--------------TSCKAPFLVDQSQKL------PAVPASSWKPPP---GLAPPQK 441
G + A LV+ PA P + + PP APP
Sbjct: 193 GAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP-- 250
Query: 442 APAASAPP-RKAPAVPA----PSQKAPAVPA--------PSQKAPAIPAPSRKASAASA- 487
APAA +PP APA PA P APA A P APA+P P+ + SA
Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG 310
Query: 488 ---SPRKASAVPAPPQKTPPP----SQKAPSVPTIPQKAVSPTAPKKKSLLL---PAPSQ 537
+P A+ PA P P + AP V K V AP L PA +
Sbjct: 311 AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTA 370
Query: 538 KALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVT--VRTQ 595
++ PT SP A PG PTG+P A +QS + T +R
Sbjct: 371 ASMVIGPTMQGALPSPAAVPPPAPG----TPTGLPKGAAGAVTQSLSRTPTATTSGIRAT 426
Query: 596 ETDVVEMTTQAKSPESPFTV 615
T V + P++P +
Sbjct: 427 LTPTVLAPRLPQPPQNPTNI 446
Score = 60.5 bits (145), Expect = 7e-09
Identities = 70/264 (26%), Positives = 94/264 (35%), Gaps = 58/264 (21%)
Query: 350 SGGSTLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQK--APSGLV 407
+G + + A G AP PP P GR + G G Q PGPP ++ P+G
Sbjct: 73 AGPAAPAEGAPGAAPEPP-----------PAGRARPGG-GGPQRPGPPSPRRPLVPAG-- 118
Query: 408 TSCKAPFLVDQSQKLPAVPASSWKPPP-----GLAPPQKAPAASAPPRKAPAVPAP---- 458
PA PA+ +PPP AP A A +A P APA PA
Sbjct: 119 ---------------PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163
Query: 459 ---SQKAPAVPAPSQKAPAIPAPSRKASAASASPRKAS---------AVPAPPQKTPPPS 506
+ +A P P P P + A +A S A PA P+
Sbjct: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
Query: 507 QKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSP------PASRGKL 560
P V T P + PAP+ + P +P A +P PA+ +
Sbjct: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARP 283
Query: 561 PGDFDVLPTGIPGRAVLERSQSGG 584
PG PT P +Q+GG
Sbjct: 284 PGHPAGPPTAAPAVPPPAAAQNGG 307
Score = 45.4 bits (106), Expect = 2e-04
Identities = 81/400 (20%), Positives = 136/400 (34%), Gaps = 50/400 (12%)
Query: 396 PPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAV 455
PPP P+GL A + + P S + L P AP PP+ +
Sbjct: 390 PPPAPGTPTGLPKGA-AGAVTQSLSRTPTATTSGIRAT--LTPTVLAPRLPQPPQNPTNI 446
Query: 456 P----------APSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPP 505
S+ + P Q + A + + +PR A+ APP +
Sbjct: 447 QNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQI--S 504
Query: 506 SQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKA-LPTSP-TEYQMALSPPASRGKLPGD 563
+ +AP P I ++ T K+ S A L SP + Q+ L A L G
Sbjct: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASL-GT 563
Query: 564 FDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDI 623
+ TG P R V T + T+ +E + K+ S K
Sbjct: 564 ATAVQTGTPQRTV----------PGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQS 613
Query: 624 --LISQTKEVTLEAFRGQGKLEDWAHWAKLEERS---PDLPGVRSKELEQRKRWVKAKEL 678
+ KE+ G+ + ED+ E S P L + L ++
Sbjct: 614 TETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAA 673
Query: 679 AVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSKSAL------------VSLPSWLLAT 726
++ Q+ P S LT ++++++ + K+A ++ P+ +
Sbjct: 674 FIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVG 733
Query: 727 PQASATSMMASVPSRPGQL-----SLLEGKPVVVREQPES 761
Q T ++ P +PG L L P+V QP +
Sbjct: 734 KQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHN 773
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/131 (28%), Positives = 44/131 (33%), Gaps = 17/131 (12%)
Query: 433 PPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKA 492
P G A A A P AP P + P P + P P+P R A +P
Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP--PSPRRPLVPAGPAP--- 121
Query: 493 SAVPAPPQKT-PPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMAL 551
P K PPP A S +P A P+ PAP+ A P P
Sbjct: 122 -----PAAKLRPPPEGSAGSCAPVPAAAAVAAGPE------PAPAGPAKPAGPAALAARA 170
Query: 552 SPPASRGKLPG 562
P G PG
Sbjct: 171 GPGPGPGPGPG 181
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 67.4 bits (163), Expect = 6e-11
Identities = 106/420 (25%), Positives = 151/420 (35%), Gaps = 55/420 (13%)
Query: 363 APYPPAACLSTPYSSIPR--GREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQ 420
AP PP A P +IP + P+ + P P P P + S
Sbjct: 771 APLPPQAP-PKPLVTIPAPTSTKTVAPVVTQAAP-PTPTPPVPPAKKQPAFPASYIPPSP 828
Query: 421 KLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSR 480
P VP PPP L P Q++ A PP VP+ ++ + P PA+ +
Sbjct: 829 PTPPVPV----PPPTL-PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPL 883
Query: 481 KASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKAL 540
K A+ +P+ AV A P K P S PS P P + SL+ P P +
Sbjct: 884 KPVPANVAPQSPPAVKAKP-KWQPSSIPVPSPD-------FPPPPPESSLVFPPPPPSPV 935
Query: 541 PTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVV 600
P P PP + P +G PG+ + S GGK P Q +
Sbjct: 936 PAPPP------PPPPTASPTPD-----KSGSPGKKTSKTSSPGGKKPPPT---PQRNSSI 981
Query: 601 EMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWA------KLEER 654
+ ++ A+ PE K+ S D L+S + T A G E A KL
Sbjct: 982 KSSSGAEHPE-----PKRPSVDSLVS---KFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033
Query: 655 SPDLPGVRSKELEQRKRWV---KAKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQP 711
+LPGV + K V + K+ VE PS F + + E P
Sbjct: 1034 GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP---PETELPLPPIEIP 1090
Query: 712 SKSALVSLPSWLLATPQASATSMM----ASVPSRPGQLSLLEGKPVVVREQPESHTWVKE 767
+ + + P + PQ S M A P+RP + + EQP T V +
Sbjct: 1091 AVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQ 1150
Score = 66.2 bits (160), Expect = 1e-10
Identities = 75/259 (28%), Positives = 96/259 (37%), Gaps = 44/259 (16%)
Query: 368 AACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPA 427
AA + YS+I R + + G+ P PP ++ S K LV + +P P
Sbjct: 660 AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQS-----VKPQILVPPNGVVPPPPP 714
Query: 428 SSWKPPPGLAPPQKAPAA--------SAPP------------RKAPAVPAPSQKAPAVPA 467
P PG A Q PA SAPP + AP P P PA P
Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA-PL 773
Query: 468 PSQKAP----AIPAPSRKASAASASPRKASAVPAPP----QKTP--PPSQKAPSVPTIPQ 517
P Q P IPAP+ + A + A P PP +K P P S PS PT P
Sbjct: 774 PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV 833
Query: 518 KAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMAL------SPPA--SRGKLPGDFDVLPT 569
PT PK++S P P Q+A +PPA S+ P +V P
Sbjct: 834 PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQ 893
Query: 570 GIPGRAVLERSQSGGKPEP 588
P + Q P P
Sbjct: 894 SPPAVKAKPKWQPSSIPVP 912
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 63/228 (27%)
Query: 426 PASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAV--PAP--------------S 469
P ++ +P P L PP P PP P P PSQ AP+ AP S
Sbjct: 618 PYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNAS 677
Query: 470 QKAPAIPAPSRKASAASASPRKA------SAVPAPPQKTPPPS--------QKAPSVPTI 515
Q + A+ P S S + VP PP PPP+ + AP P++
Sbjct: 678 QHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL 737
Query: 516 PQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRA 575
PQ + P P K + +Q A PT P PP +P +P +A
Sbjct: 738 PQFSAPP--PPLKIHQVQHITQVAPPTPPP------PPP------------IPAPLPPQA 777
Query: 576 VLERSQSGGKPEPVVTV--RTQETDVVEMTTQA--KSPESPFTVTKKE 619
P+P+VT+ T V + TQA +P P KK+
Sbjct: 778 ---------PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 67.0 bits (162), Expect = 8e-11
Identities = 64/236 (27%), Positives = 85/236 (36%), Gaps = 22/236 (9%)
Query: 353 STLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKA 412
+T S+ + A L+ S P+ A P S P PP AP +
Sbjct: 136 ATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPS-SSAPPETTAAPPT 194
Query: 413 PFLVDQSQKLPAVPASSWKPPPGLAPPQKAPA---ASAPPRKAPAVPAPSQKAPAVPAPS 469
P Q+ + P + PP PP PA +SAPP A P PS PA P S
Sbjct: 195 PSATTQAPPSSSAPPETTAAPP--TPPATTPAPPSSSAPPETTAAPPTPSATTPA-PLSS 251
Query: 470 QKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAP---- 525
P A SA + P ASA P P PS P+ P+ P + AP
Sbjct: 252 SAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTP 311
Query: 526 -KKKSLLLPAPSQ-KALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLER 579
+ L P S+ A PT T + ++ PT PG+ + R
Sbjct: 312 NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTK---------QPTSAPGQNKISR 358
Score = 63.9 bits (154), Expect = 6e-10
Identities = 62/206 (30%), Positives = 78/206 (37%), Gaps = 26/206 (12%)
Query: 436 LAP---PQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASA---ASASP 489
LAP P +APP + PAP P+ AP + A P PS A +SA P
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAP----PSSSAPPETTAAPPTPSATTQAPPSSSAPP 209
Query: 490 RKASAVPAPPQKTP-PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQ 548
+A P PP TP PPS AP T S T P S P P A+P +P+
Sbjct: 210 ETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAP-PETTAVPPTPSATT 268
Query: 549 MALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKS 608
+ P+S P PT S P P + QET +TT S
Sbjct: 269 L---DPSSASAPPETTAAPPT-----------PSATTPAPPSSPAPQETTAAPITTPNSS 314
Query: 609 PESPFTVTKKESKDILISQTKEVTLE 634
P + T + S T VT +
Sbjct: 315 PTTLAPDTSETSAAPTHQTTTSVTTQ 340
Score = 30.4 bits (67), Expect = 7.9
Identities = 40/167 (23%), Positives = 52/167 (31%), Gaps = 27/167 (16%)
Query: 725 ATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMK 784
A P SAT+ S P + + P + P S + P
Sbjct: 168 APPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSS--------------APPETTA 213
Query: 785 EPPWDPKGPPKVPFRSKP---TSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKME 841
PP P P P S P T+A + AP+ +A P P S T +
Sbjct: 214 APPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSS 273
Query: 842 A-----TARASQQPKRVSQEPMRMPAQH-----PLATVGSSSEILLP 878
A T A P + P PA P+ T SS L P
Sbjct: 274 ASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP 320
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 67.0 bits (162), Expect = 8e-11
Identities = 64/236 (27%), Positives = 85/236 (36%), Gaps = 22/236 (9%)
Query: 353 STLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKA 412
+T S+ + A L+ S P+ A P S P PP AP +
Sbjct: 136 ATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPS-SSAPPETTAAPPT 194
Query: 413 PFLVDQSQKLPAVPASSWKPPPGLAPPQKAPA---ASAPPRKAPAVPAPSQKAPAVPAPS 469
P Q+ + P + PP PP PA +SAPP A P PS PA P S
Sbjct: 195 PSATTQAPPSSSAPPETTAAPP--TPPATTPAPPSSSAPPETTAAPPTPSATTPA-PLSS 251
Query: 470 QKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAP---- 525
P A SA + P ASA P P PS P+ P+ P + AP
Sbjct: 252 SAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTP 311
Query: 526 -KKKSLLLPAPSQ-KALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLER 579
+ L P S+ A PT T + ++ PT PG+ + R
Sbjct: 312 NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTK---------QPTSAPGQNKISR 358
Score = 63.9 bits (154), Expect = 6e-10
Identities = 62/206 (30%), Positives = 78/206 (37%), Gaps = 26/206 (12%)
Query: 436 LAP---PQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASA---ASASP 489
LAP P +APP + PAP P+ AP + A P PS A +SA P
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAP----PSSSAPPETTAAPPTPSATTQAPPSSSAPP 209
Query: 490 RKASAVPAPPQKTP-PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQ 548
+A P PP TP PPS AP T S T P S P P A+P +P+
Sbjct: 210 ETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAP-PETTAVPPTPSATT 268
Query: 549 MALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKS 608
+ P+S P PT S P P + QET +TT S
Sbjct: 269 L---DPSSASAPPETTAAPPT-----------PSATTPAPPSSPAPQETTAAPITTPNSS 314
Query: 609 PESPFTVTKKESKDILISQTKEVTLE 634
P + T + S T VT +
Sbjct: 315 PTTLAPDTSETSAAPTHQTTTSVTTQ 340
Score = 30.4 bits (67), Expect = 7.9
Identities = 40/167 (23%), Positives = 52/167 (31%), Gaps = 27/167 (16%)
Query: 725 ATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMK 784
A P SAT+ S P + + P + P S + P
Sbjct: 168 APPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSS--------------APPETTA 213
Query: 785 EPPWDPKGPPKVPFRSKP---TSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKME 841
PP P P P S P T+A + AP+ +A P P S T +
Sbjct: 214 APPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSS 273
Query: 842 A-----TARASQQPKRVSQEPMRMPAQH-----PLATVGSSSEILLP 878
A T A P + P PA P+ T SS L P
Sbjct: 274 ASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP 320
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 67.0 bits (162), Expect = 8e-11
Identities = 64/236 (27%), Positives = 85/236 (36%), Gaps = 22/236 (9%)
Query: 353 STLSSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKA 412
+T S+ + A L+ S P+ A P S P PP AP +
Sbjct: 136 ATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPS-SSAPPETTAAPPT 194
Query: 413 PFLVDQSQKLPAVPASSWKPPPGLAPPQKAPA---ASAPPRKAPAVPAPSQKAPAVPAPS 469
P Q+ + P + PP PP PA +SAPP A P PS PA P S
Sbjct: 195 PSATTQAPPSSSAPPETTAAPP--TPPATTPAPPSSSAPPETTAAPPTPSATTPA-PLSS 251
Query: 470 QKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAP---- 525
P A SA + P ASA P P PS P+ P+ P + AP
Sbjct: 252 SAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTP 311
Query: 526 -KKKSLLLPAPSQ-KALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLER 579
+ L P S+ A PT T + ++ PT PG+ + R
Sbjct: 312 NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTK---------QPTSAPGQNKISR 358
Score = 63.9 bits (154), Expect = 6e-10
Identities = 62/206 (30%), Positives = 78/206 (37%), Gaps = 26/206 (12%)
Query: 436 LAP---PQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASA---ASASP 489
LAP P +APP + PAP P+ AP + A P PS A +SA P
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAP----PSSSAPPETTAAPPTPSATTQAPPSSSAPP 209
Query: 490 RKASAVPAPPQKTP-PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQ 548
+A P PP TP PPS AP T S T P S P P A+P +P+
Sbjct: 210 ETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAP-PETTAVPPTPSATT 268
Query: 549 MALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKS 608
+ P+S P PT S P P + QET +TT S
Sbjct: 269 L---DPSSASAPPETTAAPPT-----------PSATTPAPPSSPAPQETTAAPITTPNSS 314
Query: 609 PESPFTVTKKESKDILISQTKEVTLE 634
P + T + S T VT +
Sbjct: 315 PTTLAPDTSETSAAPTHQTTTSVTTQ 340
Score = 30.4 bits (67), Expect = 7.9
Identities = 40/167 (23%), Positives = 52/167 (31%), Gaps = 27/167 (16%)
Query: 725 ATPQASATSMMASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPWGEMK 784
A P SAT+ S P + + P + P S + P
Sbjct: 168 APPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSS--------------APPETTA 213
Query: 785 EPPWDPKGPPKVPFRSKP---TSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKME 841
PP P P P S P T+A + AP+ +A P P S T +
Sbjct: 214 APPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSS 273
Query: 842 A-----TARASQQPKRVSQEPMRMPAQH-----PLATVGSSSEILLP 878
A T A P + P PA P+ T SS L P
Sbjct: 274 ASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP 320
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 66.2 bits (160), Expect = 1e-10
Identities = 77/271 (28%), Positives = 108/271 (39%), Gaps = 40/271 (14%)
Query: 361 GLAPYPPAACLSTPYSSIPRG---REKAGPMGSHQGPGP------PPCQKAP-------- 403
G P P A L S P G +++ P G PGP PP Q+ P
Sbjct: 434 GQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHL 493
Query: 404 SGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAA-SAPPRKAPAVPAPSQKA 462
SGL +P Q+LP+ ++ +P APP + S P P P P+ +
Sbjct: 494 SGLGPPAGSPL----PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP-PAARP 548
Query: 463 PAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSP 522
PA P+P ++A P +R+ S + +P KAS P Q+ P QK P P P + S
Sbjct: 549 PASPSPQRQA-GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG-PAGPTRQASQ 606
Query: 523 TAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLP-----TGIPGRAVL 577
P ++ P +Q+ P+ P A P + P DV P G P L
Sbjct: 607 AGPVPRT--GPPTTQQPRPSGPGP---AGRPKPQLAQKPSQ-DVPPPATAAAGGPPHPQL 660
Query: 578 ERSQS----GGKPEPVVTVRTQETDVVEMTT 604
+SQS PEP + D V+ T
Sbjct: 661 NKSQSLTNAFNLPEPAPPRPSLSQDEVKAET 691
Score = 38.5 bits (88), Expect = 0.029
Identities = 40/151 (26%), Positives = 46/151 (30%), Gaps = 19/151 (12%)
Query: 366 PPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAV 425
PP A T S + P G Q GPP P+G P
Sbjct: 560 PPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-----------------PTR 602
Query: 426 PASSWKPPPGLAPP-QKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASA 484
AS P P PP + P S P P +QK P+ P A P
Sbjct: 603 QASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQK-PSQDVPPPATAAAGGPPHPQLN 661
Query: 485 ASASPRKASAVPAPPQKTPPPSQKAPSVPTI 515
S S A +P P P SQ TI
Sbjct: 662 KSQSLTNAFNLPEPAPPRPSLSQDEVKAETI 692
Score = 32.7 bits (73), Expect = 1.6
Identities = 35/136 (25%), Positives = 52/136 (38%), Gaps = 35/136 (25%)
Query: 434 PGLAPPQKAPAASAPP-----RKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASAS 488
PG + P+ A P + PA P Q+ P P Q P P R+
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG---PQRQG------ 478
Query: 489 PRKASAVPAPPQKTPPPSQK------APSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPT 542
P Q+ PP Q+ P+ +PQ+ SPT+ ++ P+ +A P
Sbjct: 479 -------PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ------PASQAAP- 524
Query: 543 SPTEYQMALSPPASRG 558
PT+ Q S P + G
Sbjct: 525 -PTQGQGRQSRPVAGG 539
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 66.2 bits (160), Expect = 1e-10
Identities = 59/213 (27%), Positives = 71/213 (33%), Gaps = 12/213 (5%)
Query: 354 TLSSAASGLAPYPPAACLS---TPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSC 410
T A L P P A + P S P + A P G + P P P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417
Query: 411 KAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKA------PAVPAPSQKAPA 464
P + PA K P P K PA A P K P P PA
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 465 VPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQ---KTPPPSQKAPSVPTIPQKAVS 521
P P Q PA P P + SA S + S P P Q P P Q + P Q +
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 522 PTAPKKKSLLLPAPSQKALPTSPTEYQMALSPP 554
+ ++ S P+ Q P S T L PP
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/148 (36%), Positives = 66/148 (44%), Gaps = 14/148 (9%)
Query: 393 GPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLA-PPQKAPAASAPPRK 451
GPG P Q+A G TS + +LP PA PG A PP + P ++ PP +
Sbjct: 445 GPGKIPAQQAGPGK-TSAQQTGPTKPPSQLPG-PAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 452 APAV--PAPSQKAPAVPAPSQ----KAPAIPAPSRKASAASASPRKASAVPAPPQKTPPP 505
P P P Q PA P+P Q K P+ S K SA SP K P+ Q T P
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK----PSAQQSTKPV 558
Query: 506 SQKAPSVPTIPQKAVSPTAPKKKSLLLP 533
SQ P P VSP+A + S LP
Sbjct: 559 SQTGSGKPLQP-PTVSPSAKQPPSQGLP 585
Score = 61.2 bits (147), Expect = 4e-09
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 10/181 (5%)
Query: 366 PPAACLSTPYSSIPRGREKAGPMGSHQGPGP---PPCQKAPSGLVTSCKAPFLVDQSQKL 422
PP + TP ++ G + PGP P Q P + P Q
Sbjct: 410 PPTQQVGTPKPLA----QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAV-PAPSQKAPAIPAPSRK 481
P P S P P PPQ+ A PP++ + PSQ+ + P P Q PA P+P +
Sbjct: 466 PTKPPSQL-PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
Query: 482 ASAASASPRKASAVPAPPQKTP-PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKAL 540
S S + SA P+ Q +P PS + + P + P P S P + L
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Query: 541 P 541
P
Sbjct: 585 P 585
Score = 58.9 bits (141), Expect = 2e-08
Identities = 182/881 (20%), Positives = 304/881 (34%), Gaps = 151/881 (17%)
Query: 159 PAPTWTPRTTRTAPLDMPLAEAPASTWHLQDQPISRHAVRVAERNFPHKTVAAQRQRKAK 218
P P+ +TAP+ A + +S Q P K AA +Q +K
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP---------------KKDAAPKQDLSK 696
Query: 219 ALKRS-----FKSQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDP-RPDRTHTQIRLPEK 272
A + K + S Q AD KPA K S P D+ P++
Sbjct: 697 APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 273 TSITTWTIFSIISSTANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSC 332
+ T + SS+A P + + E + + + P G +
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 333 SSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSI-PRGREKAGPMGSH 391
S D++ + G S+ S + P + + P+ K P GS
Sbjct: 817 DSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP 876
Query: 392 QGPGPPPC--------QKAPSGLVTSCKAPF----LVDQSQKLPAVP------------- 426
PGP P Q++P S + + D + P P
Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 427 -----ASSWKPPPGLAPPQKAPAASAPPRKAPAVPAP--SQKAPAVPAPSQKAPAIPAPS 479
AS+ G P AP ++APA P SQ P + APA P
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 480 RKASAASASPR---KASAVP----APPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLL 532
+K + A A+ + KA P +K PPP + + S+ PQKAV PT +K
Sbjct: 997 KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS---- 1052
Query: 533 PAPSQKALPTSPTEYQMALSPPAS-------RGKLPGDFDVLPT---------------- 569
P P + P TE + P + + ++ PT
Sbjct: 1053 PKP-ESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQT 1111
Query: 570 --GIPGR----AVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDI 623
I G+ + + SG K P+ + + Q K + K E++ +
Sbjct: 1112 QRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV 1171
Query: 624 LISQTKE----------VTLEAFRGQGKLEDWAHWAKLEERS--------PDLPGVRSKE 665
++ + KE VT + + + KLE A E++ P+ +RS+E
Sbjct: 1172 ILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEE 1231
Query: 666 ----LEQRKRWVKAKELAVEGPS-----QEHSRPFSVEALTLTKL-----MITANSKEQP 711
LE++K + K+L E + Q+H S + KL T +QP
Sbjct: 1232 KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291
Query: 712 SKSALVSLPSWLLATPQA------SATSMMASVP-----SRPGQLSLLEGKPVVVREQPE 760
++ + LPS TPQ+ T + P ++P Q+ GK +E +
Sbjct: 1292 -QTKMEGLPS---GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVE--PGKEKTEKEDDK 1345
Query: 761 SHTWVKEGKRPWGEMKEQPWGEMKEPPWDPKG--PPKVPFRSKPTSASLKREGISQAPIP 818
S T ++P G + G P +P K LK++ SQ P
Sbjct: 1346 SDT--SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 819 LTASPWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLP 878
+ S L + LS I + +A+ A ++ ++ +Q P Q S L
Sbjct: 1404 SSPSDLAKLESTVLS---ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLE 1460
Query: 879 MLLELETVRNTATKAEEIQEESGVLNLLPSLQHSQHSEWPD 919
+ + E ++ + + ++ ++ ++ S H + SE+ D
Sbjct: 1461 ITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVD 1501
Score = 55.1 bits (131), Expect = 3e-07
Identities = 59/231 (25%), Positives = 82/231 (35%), Gaps = 61/231 (26%)
Query: 381 GREKAGPMGSHQGPGPPPCQKAPSGLVT-------SCKAPFLVDQSQKLPAVPASSWKPP 433
G EK+ P GP PP Q PSGL + K P + K PA P KPP
Sbjct: 320 GHEKSQP-----GPAKPPAQ--PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Query: 434 ----------------------PGLAP-PQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQ 470
PG+ P + P + PP + P P + P + +P++
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 471 ---------------KAPAIPAPSRKASAASASPRKA-SAVPAP----PQKT----PPPS 506
K PA A K SA P K S +P P PQ+ PPP
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
Query: 507 QKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASR 557
Q + P Q + P++ P+P Q P++ + P A +
Sbjct: 493 QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543
Score = 52.4 bits (124), Expect = 2e-06
Identities = 115/484 (23%), Positives = 170/484 (35%), Gaps = 75/484 (15%)
Query: 367 PAACLSTPYSSIPRGREKAGPMGSH----QGPGPPPCQKAPSGLVTSCKAPFLVDQSQKL 422
P T ++ +P R+ + P +G P +PS K P K
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPS------KPPIQQPTPGKP 314
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPR-------KAPAVPAPSQKAPAVPAPSQKAPAI 475
PA K PG A P P+ P K P P + K PA P K PA
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 476 PAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAP 535
S K S+ P KA A P KT P Q P+ P P
Sbjct: 375 QTGSEKPSSEQPGP-KALAQPPGVGKT-PAQQPGPAKP---------------------P 411
Query: 536 SQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSG-GKPEPVVTVRT 594
+Q+ P Q L PA K PG P PG + Q+G GK
Sbjct: 412 TQQVGTPKPLAQQPGLQSPA---KAPGPTKT-PVQQPGPGKIPAQQAGPGK------TSA 461
Query: 595 QETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEER 654
Q+T + +Q P P +K Q + G + +
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKP--PPQQPGSAKPPSQQPGSTKPPPQQPGPAKP 519
Query: 655 SPDLPGVRSKELEQRKRWVK--AKELAVEGPS-QEHSRPFSV--EALTLTKLMITANSKE 709
SP PG +K Q+ K A++ + PS Q+ ++P S L ++ ++K+
Sbjct: 520 SPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578
Query: 710 QPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVR---EQPESH-TWV 765
PS+ LP + P + T ++ VP + + E + V P H T V
Sbjct: 579 PPSQ----GLPKTI--CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 766 KEGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWE 825
KE +MK G++ P P+ PK+ T++++ + +P P SP +
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSSPQ--PKLKTAPVTTTSAVSK----SSPQPQQTSPKK 686
Query: 826 DLRP 829
D P
Sbjct: 687 DAAP 690
Score = 48.9 bits (115), Expect = 2e-05
Identities = 108/462 (23%), Positives = 169/462 (36%), Gaps = 83/462 (17%)
Query: 442 APAASAPPRKAPAVPAPSQKA--PAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPP 499
AP S+P K P + A + P P Q +P K AA K AP
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP-------KKDAAP----KQDLSKAPE 699
Query: 500 QKTPPPSQKAPSVPTIPQ-KAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRG 558
K PPP K P++ P KA P P+ SL PAP ++ P+ P+E A P +
Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQP--PEADSLSKPAPPKE--PSVPSEQDKA---PVADD 752
Query: 559 KLPGDFDVLPTGIPGRAVLERSQSGGKPE-PVVTVRTQ--ETDVVEMTTQAKSPESPFTV 615
K V PT ++ S + KP+ P V++Q E + T + P F
Sbjct: 753 KPKQPKMVKPT----TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808
Query: 616 TKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVK- 674
T ++ +S + K+ + + + V+ KE E +K K
Sbjct: 809 TGEK-----VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE-EPKKAQTKM 862
Query: 675 -----AKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSK-----SALVSLPSWLL 724
AK + P+ RP + + T+ + +EQ + ++ P
Sbjct: 863 SPKPDAKPMPKGSPTPPGPRPTAGQ--TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920
Query: 725 ATPQASATSMM----ASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPW 780
TPQ + T + AS+ S+ L G+P P S + P MK+ P
Sbjct: 921 TTPQETVTGKLFGFGASIFSQASNLISTAGQP-----GPHSQS------GPGAPMKQAP- 968
Query: 781 GEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKM 840
+PP +GPPK ++ P P + P + +P +E K+
Sbjct: 969 -APSQPP-TSQGPPKSTGQAPPA--------------PAKSIPVKKETKAPAAE----KL 1008
Query: 841 EATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLE 882
E A + KR E P + + + +LP LE
Sbjct: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE 1050
Score = 43.5 bits (101), Expect = 0.001
Identities = 76/351 (21%), Positives = 126/351 (35%), Gaps = 57/351 (16%)
Query: 226 SQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDPRPDRTHTQIRLPEKTSITTWTIFSIIS 285
S+ + S S +++ + ++ + D R H I L + S SII
Sbjct: 2223 SEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS-------SIIE 2275
Query: 286 STANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTE 345
S + + P A T ++D + + P ++ +G L + ++D +
Sbjct: 2276 SVVPKPEG-PVADTVSTDLLISE----KDPVKKAKKETGNGIILEVLEA------YRDKK 2324
Query: 346 DLMDSGGSTLSSAASGLAPYPPAACLSTPYSS-IPRGREKAGPMGSHQGPGPPPCQKAPS 404
+L T SS + + +PP++ ++ P + +G + P +PS
Sbjct: 2325 EL--EAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382
Query: 405 GLVTSCKA---PFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPS-- 459
V+S A PF S + A P PPP PP P PP P P P+
Sbjct: 2383 --VSSLPAKPRPFFRSSSLDISAQPPPPPPPPP--PPPPPPPPPPPPPLPPPTSPKPTIL 2438
Query: 460 -QKAPAVPAPSQKAP------------------AIPAPSRKASAASASPRKASAVPA--- 497
+K V +P A +P +A P K S++P+
Sbjct: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498
Query: 498 ---PPQKTPPPSQKAPSVPTIPQKAVSPT--APKKKSLLLPAPSQKALPTS 543
P+ + PP P +P +P PT PK L L + L TS
Sbjct: 2499 FTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS 2549
Score = 37.7 bits (86), Expect = 0.050
Identities = 121/580 (20%), Positives = 198/580 (34%), Gaps = 100/580 (17%)
Query: 378 IPRGREKAGPMGSH-QGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGL 436
+P G A G G G P P+G+ + ++ +++ AV + + P G
Sbjct: 12 LPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADL-SQLSEEERRQIAAVMSRAQGLPKGS 70
Query: 437 APPQKAPA----------ASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPA----PSRKA 482
PP A + +S PP+++ P P + A + S+ + P R
Sbjct: 71 VPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSP 130
Query: 483 SAASASPRKA-----------------------SAVPAPPQKTPP-----PSQKAPSVPT 514
S S K+ SAV + K P S+ + T
Sbjct: 131 STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETT 190
Query: 515 IPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGR 574
QK V K + ++ P Q+ P P Q G+ P D P I +
Sbjct: 191 KKQKVVQKEQGKPEGIIKPPLQQQ--PPKPIPKQQG------PGRDPLQQDGTPKSISSQ 242
Query: 575 AVLE-RSQSGGKPEPVV-TVRTQETDVVEMTTQ--AKSPESPFT-VTKKES-KDILISQT 628
+ +SQ G +P+ +T +TD ++ Q A P++ + + ES K L S +
Sbjct: 243 QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302
Query: 629 KEVTLEAFRGQGKLEDWAHWAKLE--ERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQE 686
K + G+ + H + P P +K L Q+ VK + G ++
Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP-VQPPGTTKP 361
Query: 687 HSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLS 746
++P + S EQP AL P T P++P
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG-------VGKTPAQQPGPAKPPTQQ 414
Query: 747 LLEGKPVVVREQPESHTWVKE-------------GKRPW-----GEMKEQPWGEMK---- 784
+ G P + +QP + K GK P G+ Q G K
Sbjct: 415 V--GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 785 -----EPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISK 839
+PP GP K P + ++ ++ S P P P + P S S+
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 840 MEATARAS-QQPKRVSQEPMRMPAQHPLATVGSSSEILLP 878
+A+ S QQP +P + P++ GS + P
Sbjct: 533 QPGSAKPSAQQPS--PAKPSAQQSTKPVSQTGSGKPLQPP 570
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 66.2 bits (160), Expect = 1e-10
Identities = 59/213 (27%), Positives = 71/213 (33%), Gaps = 12/213 (5%)
Query: 354 TLSSAASGLAPYPPAACLS---TPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSC 410
T A L P P A + P S P + A P G + P P P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417
Query: 411 KAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKA------PAVPAPSQKAPA 464
P + PA K P P K PA A P K P P PA
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 465 VPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQ---KTPPPSQKAPSVPTIPQKAVS 521
P P Q PA P P + SA S + S P P Q P P Q + P Q +
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 522 PTAPKKKSLLLPAPSQKALPTSPTEYQMALSPP 554
+ ++ S P+ Q P S T L PP
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/148 (36%), Positives = 66/148 (44%), Gaps = 14/148 (9%)
Query: 393 GPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLA-PPQKAPAASAPPRK 451
GPG P Q+A G TS + +LP PA PG A PP + P ++ PP +
Sbjct: 445 GPGKIPAQQAGPGK-TSAQQTGPTKPPSQLPG-PAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 452 APAV--PAPSQKAPAVPAPSQ----KAPAIPAPSRKASAASASPRKASAVPAPPQKTPPP 505
P P P Q PA P+P Q K P+ S K SA SP K P+ Q T P
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK----PSAQQSTKPV 558
Query: 506 SQKAPSVPTIPQKAVSPTAPKKKSLLLP 533
SQ P P VSP+A + S LP
Sbjct: 559 SQTGSGKPLQP-PTVSPSAKQPPSQGLP 585
Score = 61.2 bits (147), Expect = 4e-09
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 10/181 (5%)
Query: 366 PPAACLSTPYSSIPRGREKAGPMGSHQGPGP---PPCQKAPSGLVTSCKAPFLVDQSQKL 422
PP + TP ++ G + PGP P Q P + P Q
Sbjct: 410 PPTQQVGTPKPLA----QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAV-PAPSQKAPAIPAPSRK 481
P P S P P PPQ+ A PP++ + PSQ+ + P P Q PA P+P +
Sbjct: 466 PTKPPSQL-PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
Query: 482 ASAASASPRKASAVPAPPQKTP-PPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKAL 540
S S + SA P+ Q +P PS + + P + P P S P + L
Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Query: 541 P 541
P
Sbjct: 585 P 585
Score = 58.9 bits (141), Expect = 2e-08
Identities = 182/881 (20%), Positives = 304/881 (34%), Gaps = 151/881 (17%)
Query: 159 PAPTWTPRTTRTAPLDMPLAEAPASTWHLQDQPISRHAVRVAERNFPHKTVAAQRQRKAK 218
P P+ +TAP+ A + +S Q P K AA +Q +K
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP---------------KKDAAPKQDLSK 696
Query: 219 ALKRS-----FKSQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDP-RPDRTHTQIRLPEK 272
A + K + S Q AD KPA K S P D+ P++
Sbjct: 697 APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 273 TSITTWTIFSIISSTANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSC 332
+ T + SS+A P + + E + + + P G +
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 333 SSLDPCLWHQDTEDLMDSGGSTLSSAASGLAPYPPAACLSTPYSSI-PRGREKAGPMGSH 391
S D++ + G S+ S + P + + P+ K P GS
Sbjct: 817 DSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP 876
Query: 392 QGPGPPPC--------QKAPSGLVTSCKAPF----LVDQSQKLPAVP------------- 426
PGP P Q++P S + + D + P P
Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 427 -----ASSWKPPPGLAPPQKAPAASAPPRKAPAVPAP--SQKAPAVPAPSQKAPAIPAPS 479
AS+ G P AP ++APA P SQ P + APA P
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 480 RKASAASASPR---KASAVP----APPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLL 532
+K + A A+ + KA P +K PPP + + S+ PQKAV PT +K
Sbjct: 997 KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS---- 1052
Query: 533 PAPSQKALPTSPTEYQMALSPPAS-------RGKLPGDFDVLPT---------------- 569
P P + P TE + P + + ++ PT
Sbjct: 1053 PKP-ESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQT 1111
Query: 570 --GIPGR----AVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDI 623
I G+ + + SG K P+ + + Q K + K E++ +
Sbjct: 1112 QRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV 1171
Query: 624 LISQTKE----------VTLEAFRGQGKLEDWAHWAKLEERS--------PDLPGVRSKE 665
++ + KE VT + + + KLE A E++ P+ +RS+E
Sbjct: 1172 ILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEE 1231
Query: 666 ----LEQRKRWVKAKELAVEGPS-----QEHSRPFSVEALTLTKL-----MITANSKEQP 711
LE++K + K+L E + Q+H S + KL T +QP
Sbjct: 1232 KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291
Query: 712 SKSALVSLPSWLLATPQA------SATSMMASVP-----SRPGQLSLLEGKPVVVREQPE 760
++ + LPS TPQ+ T + P ++P Q+ GK +E +
Sbjct: 1292 -QTKMEGLPS---GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVE--PGKEKTEKEDDK 1345
Query: 761 SHTWVKEGKRPWGEMKEQPWGEMKEPPWDPKG--PPKVPFRSKPTSASLKREGISQAPIP 818
S T ++P G + G P +P K LK++ SQ P
Sbjct: 1346 SDT--SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 819 LTASPWEDLRPSPLSETLISKMEATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLP 878
+ S L + LS I + +A+ A ++ ++ +Q P Q S L
Sbjct: 1404 SSPSDLAKLESTVLS---ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLE 1460
Query: 879 MLLELETVRNTATKAEEIQEESGVLNLLPSLQHSQHSEWPD 919
+ + E ++ + + ++ ++ ++ S H + SE+ D
Sbjct: 1461 ITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVD 1501
Score = 55.1 bits (131), Expect = 3e-07
Identities = 59/231 (25%), Positives = 82/231 (35%), Gaps = 61/231 (26%)
Query: 381 GREKAGPMGSHQGPGPPPCQKAPSGLVT-------SCKAPFLVDQSQKLPAVPASSWKPP 433
G EK+ P GP PP Q PSGL + K P + K PA P KPP
Sbjct: 320 GHEKSQP-----GPAKPPAQ--PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Query: 434 ----------------------PGLAP-PQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQ 470
PG+ P + P + PP + P P + P + +P++
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 471 ---------------KAPAIPAPSRKASAASASPRKA-SAVPAP----PQKT----PPPS 506
K PA A K SA P K S +P P PQ+ PPP
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
Query: 507 QKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASR 557
Q + P Q + P++ P+P Q P++ + P A +
Sbjct: 493 QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543
Score = 52.4 bits (124), Expect = 2e-06
Identities = 115/484 (23%), Positives = 170/484 (35%), Gaps = 75/484 (15%)
Query: 367 PAACLSTPYSSIPRGREKAGPMGSH----QGPGPPPCQKAPSGLVTSCKAPFLVDQSQKL 422
P T ++ +P R+ + P +G P +PS K P K
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPS------KPPIQQPTPGKP 314
Query: 423 PAVPASSWKPPPGLAPPQKAPAASAPPR-------KAPAVPAPSQKAPAVPAPSQKAPAI 475
PA K PG A P P+ P K P P + K PA P K PA
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 476 PAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAP 535
S K S+ P KA A P KT P Q P+ P P
Sbjct: 375 QTGSEKPSSEQPGP-KALAQPPGVGKT-PAQQPGPAKP---------------------P 411
Query: 536 SQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSG-GKPEPVVTVRT 594
+Q+ P Q L PA K PG P PG + Q+G GK
Sbjct: 412 TQQVGTPKPLAQQPGLQSPA---KAPGPTKT-PVQQPGPGKIPAQQAGPGK------TSA 461
Query: 595 QETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEER 654
Q+T + +Q P P +K Q + G + +
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKP--PPQQPGSAKPPSQQPGSTKPPPQQPGPAKP 519
Query: 655 SPDLPGVRSKELEQRKRWVK--AKELAVEGPS-QEHSRPFSV--EALTLTKLMITANSKE 709
SP PG +K Q+ K A++ + PS Q+ ++P S L ++ ++K+
Sbjct: 520 SPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578
Query: 710 QPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLSLLEGKPVVVR---EQPESH-TWV 765
PS+ LP + P + T ++ VP + + E + V P H T V
Sbjct: 579 PPSQ----GLPKTI--CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 766 KEGKRPWGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWE 825
KE +MK G++ P P+ PK+ T++++ + +P P SP +
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSSPQ--PKLKTAPVTTTSAVSK----SSPQPQQTSPKK 686
Query: 826 DLRP 829
D P
Sbjct: 687 DAAP 690
Score = 48.9 bits (115), Expect = 2e-05
Identities = 108/462 (23%), Positives = 169/462 (36%), Gaps = 83/462 (17%)
Query: 442 APAASAPPRKAPAVPAPSQKA--PAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPP 499
AP S+P K P + A + P P Q +P K AA K AP
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP-------KKDAAP----KQDLSKAPE 699
Query: 500 QKTPPPSQKAPSVPTIPQ-KAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRG 558
K PPP K P++ P KA P P+ SL PAP ++ P+ P+E A P +
Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQP--PEADSLSKPAPPKE--PSVPSEQDKA---PVADD 752
Query: 559 KLPGDFDVLPTGIPGRAVLERSQSGGKPE-PVVTVRTQ--ETDVVEMTTQAKSPESPFTV 615
K V PT ++ S + KP+ P V++Q E + T + P F
Sbjct: 753 KPKQPKMVKPT----TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808
Query: 616 TKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVK- 674
T ++ +S + K+ + + + V+ KE E +K K
Sbjct: 809 TGEK-----VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE-EPKKAQTKM 862
Query: 675 -----AKELAVEGPSQEHSRPFSVEALTLTKLMITANSKEQPSK-----SALVSLPSWLL 724
AK + P+ RP + + T+ + +EQ + ++ P
Sbjct: 863 SPKPDAKPMPKGSPTPPGPRPTAGQ--TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920
Query: 725 ATPQASATSMM----ASVPSRPGQLSLLEGKPVVVREQPESHTWVKEGKRPWGEMKEQPW 780
TPQ + T + AS+ S+ L G+P P S + P MK+ P
Sbjct: 921 TTPQETVTGKLFGFGASIFSQASNLISTAGQP-----GPHSQS------GPGAPMKQAP- 968
Query: 781 GEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISKM 840
+PP +GPPK ++ P P + P + +P +E K+
Sbjct: 969 -APSQPP-TSQGPPKSTGQAPPA--------------PAKSIPVKKETKAPAAE----KL 1008
Query: 841 EATARASQQPKRVSQEPMRMPAQHPLATVGSSSEILLPMLLE 882
E A + KR E P + + + +LP LE
Sbjct: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE 1050
Score = 43.5 bits (101), Expect = 0.001
Identities = 76/351 (21%), Positives = 126/351 (35%), Gaps = 57/351 (16%)
Query: 226 SQAVGDSVPLIWSQLEHADVRKKPAEKKSHSDPRPDRTHTQIRLPEKTSITTWTIFSIIS 285
S+ + S S +++ + ++ + D R H I L + S SII
Sbjct: 2223 SEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS-------SIIE 2275
Query: 286 STANQTQSSPKACTSASDEATGQGHVVESPSHCVSADSPDGFFLGSCSSLDPCLWHQDTE 345
S + + P A T ++D + + P ++ +G L + ++D +
Sbjct: 2276 SVVPKPEG-PVADTVSTDLLISE----KDPVKKAKKETGNGIILEVLEA------YRDKK 2324
Query: 346 DLMDSGGSTLSSAASGLAPYPPAACLSTPYSS-IPRGREKAGPMGSHQGPGPPPCQKAPS 404
+L T SS + + +PP++ ++ P + +G + P +PS
Sbjct: 2325 EL--EAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382
Query: 405 GLVTSCKA---PFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPS-- 459
V+S A PF S + A P PPP PP P PP P P P+
Sbjct: 2383 --VSSLPAKPRPFFRSSSLDISAQPPPPPPPPP--PPPPPPPPPPPPPLPPPTSPKPTIL 2438
Query: 460 -QKAPAVPAPSQKAP------------------AIPAPSRKASAASASPRKASAVPA--- 497
+K V +P A +P +A P K S++P+
Sbjct: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498
Query: 498 ---PPQKTPPPSQKAPSVPTIPQKAVSPT--APKKKSLLLPAPSQKALPTS 543
P+ + PP P +P +P PT PK L L + L TS
Sbjct: 2499 FTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS 2549
Score = 37.7 bits (86), Expect = 0.050
Identities = 121/580 (20%), Positives = 198/580 (34%), Gaps = 100/580 (17%)
Query: 378 IPRGREKAGPMGSH-QGPGPPPCQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGL 436
+P G A G G G P P+G+ + ++ +++ AV + + P G
Sbjct: 12 LPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADL-SQLSEEERRQIAAVMSRAQGLPKGS 70
Query: 437 APPQKAPA----------ASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPA----PSRKA 482
PP A + +S PP+++ P P + A + S+ + P R
Sbjct: 71 VPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSP 130
Query: 483 SAASASPRKA-----------------------SAVPAPPQKTPP-----PSQKAPSVPT 514
S S K+ SAV + K P S+ + T
Sbjct: 131 STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETT 190
Query: 515 IPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGR 574
QK V K + ++ P Q+ P P Q G+ P D P I +
Sbjct: 191 KKQKVVQKEQGKPEGIIKPPLQQQ--PPKPIPKQQG------PGRDPLQQDGTPKSISSQ 242
Query: 575 AVLE-RSQSGGKPEPVV-TVRTQETDVVEMTTQ--AKSPESPFT-VTKKES-KDILISQT 628
+ +SQ G +P+ +T +TD ++ Q A P++ + + ES K L S +
Sbjct: 243 QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302
Query: 629 KEVTLEAFRGQGKLEDWAHWAKLE--ERSPDLPGVRSKELEQRKRWVKAKELAVEGPSQE 686
K + G+ + H + P P +K L Q+ VK + G ++
Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP-VQPPGTTKP 361
Query: 687 HSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASVPSRPGQLS 746
++P + S EQP AL P T P++P
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG-------VGKTPAQQPGPAKPPTQQ 414
Query: 747 LLEGKPVVVREQPESHTWVKE-------------GKRPW-----GEMKEQPWGEMK---- 784
+ G P + +QP + K GK P G+ Q G K
Sbjct: 415 V--GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 785 -----EPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSPLSETLISK 839
+PP GP K P + ++ ++ S P P P + P S S+
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 840 MEATARAS-QQPKRVSQEPMRMPAQHPLATVGSSSEILLP 878
+A+ S QQP +P + P++ GS + P
Sbjct: 533 QPGSAKPSAQQPS--PAKPSAQQSTKPVSQTGSGKPLQPP 570
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 65.9 bits (159), Expect = 2e-10
Identities = 59/202 (29%), Positives = 86/202 (42%), Gaps = 27/202 (13%)
Query: 361 GLAPYPPAACLSTPYSSIPRG---REKAGPMGSHQGPGP------PPCQKAP-------- 403
G P P A L S P G +++ P G PGP PP Q+ P
Sbjct: 434 GQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHL 493
Query: 404 SGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAA-SAPPRKAPAVPAPSQKA 462
SGL +P Q+LP+ ++ +P APP + S P P P P+ +
Sbjct: 494 SGLGPPAGSPL----PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP-PAARP 548
Query: 463 PAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSP 522
PA P+P ++A P +R+ S + +P KAS P Q+ P QK P P P + S
Sbjct: 549 PASPSPQRQA-GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG-PAGPTRQASQ 606
Query: 523 TAPKKKSLLLPAPSQKALPTSP 544
P ++ P +Q+ P+ P
Sbjct: 607 AGPVPRT--GPPTTQQPRPSGP 626
Score = 53.9 bits (128), Expect = 7e-07
Identities = 50/164 (30%), Positives = 64/164 (39%), Gaps = 17/164 (10%)
Query: 363 APYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKA--PFLVDQ-S 419
AP PA+ + P +GR+ G GPG PP + P+ +A P Q S
Sbjct: 514 APQQPASQAAPPTQG--QGRQSRPVAG---GPGAPPAARPPASPSPQRQAGPPQATRQTS 568
Query: 420 QKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKA-PAVPAPSQKAPAIPAP 478
PA P +S PP G PP+K P P+++A A P P P P
Sbjct: 569 VSGPAPPKASGAPPGG-------QQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQP 621
Query: 479 SRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSP 522
R + A K P Q PPP+ A P PQ SP
Sbjct: 622 -RPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664
Score = 32.7 bits (73), Expect = 1.6
Identities = 35/136 (25%), Positives = 52/136 (38%), Gaps = 35/136 (25%)
Query: 434 PGLAPPQKAPAASAPP-----RKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASAS 488
PG + P+ A P + PA P Q+ P P Q P P R+
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG---PQRQG------ 478
Query: 489 PRKASAVPAPPQKTPPPSQK------APSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPT 542
P Q+ PP Q+ P+ +PQ+ SPT+ ++ P+ +A P
Sbjct: 479 -------PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ------PASQAAP- 524
Query: 543 SPTEYQMALSPPASRG 558
PT+ Q S P + G
Sbjct: 525 -PTQGQGRQSRPVAGG 539
>gi|193083150 hypothetical protein LOC346653 isoform b [Homo
sapiens]
Length = 300
Score = 65.9 bits (159), Expect = 2e-10
Identities = 43/126 (34%), Positives = 68/126 (53%), Gaps = 12/126 (9%)
Query: 43 MFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLPDILLIGQP----------AED 92
+FESNF+QVT G V + + +GV +S+P L LP++LL+ +
Sbjct: 44 VFESNFIQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNVLLMANVTWPQGPFTTWSTP 103
Query: 93 RDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRLVSGRQYYLALDAPDNEVGFLFHCWVRL 152
D + L+R++PL V L ++D L++R V+ + YYL L E+ F F WVRL
Sbjct: 104 GDAPVINLSRLLPLKYVELRIYDRLQRILRVRTVTEKIYYLKLHEKHPEIVFQF--WVRL 161
Query: 153 INLLQE 158
+ +LQ+
Sbjct: 162 VKILQK 167
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 65.5 bits (158), Expect = 2e-10
Identities = 60/217 (27%), Positives = 86/217 (39%), Gaps = 31/217 (14%)
Query: 357 SAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPP----CQKAPSGLVTSCKA 412
SA +G +P A ++ P + G+ +GP P + P
Sbjct: 946 SAVAGFSPEWAALAITVPITEED---------GTPEGPVTPATTVHAPEEPDTAAVRVST 996
Query: 413 PFLVDQSQKLPAVPASSWKPPPGLAPPQK----APAASAPPRKAPAVPAPSQKAPAVPAP 468
P + + AVP P A P +PAA+ PP + P PA + P P
Sbjct: 997 P--EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA--VPTPEEP 1052
Query: 469 SQKAPAIPAPSRKASAASASP------RKASAVPAPPQKTPPPSQ-KAPSVPTIPQKAV- 520
+ A A+P P S A+A P A+AVP P + T P + P PT P AV
Sbjct: 1053 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1112
Query: 521 SPTAPKKKSLLLPAPSQKALPTS--PTEYQMALSPPA 555
+P P + +P P + A P + PT + A PA
Sbjct: 1113 TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA 1149
Score = 62.8 bits (151), Expect = 1e-09
Identities = 58/216 (26%), Positives = 85/216 (39%), Gaps = 34/216 (15%)
Query: 364 PYPPAACLSTPY------SSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVD 417
P PAA + TP +++P E P + P P +P+ V + + P
Sbjct: 1052 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEEPTSPA 1108
Query: 418 QSQKLPAVPASSWKPPPGLAPPQK--APAASAPPRKAPAVPAPSQKAPAVPAPSQKAP-- 473
+ P PAS P + P++ +PAA+ P + PA PAP AVP P + A
Sbjct: 1109 AAVPTPEEPAS---PAAAVPTPEEPASPAAAVPTPEEPAFPAP-----AVPTPEESASAA 1160
Query: 474 -AIPAPSRKASAASASPRKASAV------------PAPPQKTPPPSQKAPSVPTIPQKAV 520
A+P P AS A+A P A + +P P P+ ++ A
Sbjct: 1161 VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAA 1220
Query: 521 SPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPAS 556
S ++ + L A S PTSP L P S
Sbjct: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTS 1256
Score = 55.1 bits (131), Expect = 3e-07
Identities = 71/287 (24%), Positives = 105/287 (36%), Gaps = 49/287 (17%)
Query: 364 PYPPAACLSTPYSS------IPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFLVD 417
P PA + TP S +P E A P + P P + A V +
Sbjct: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASPAAAV----PTPAESASFAAVVA-------- 1190
Query: 418 QSQKLPAVPASSWKPPPGLAPPQK---APAASAPPRKAPAVPAPSQKAPAVP-APSQKAP 473
+ + P PA+S P + + +PAAS P + PA A + P P +P+ P
Sbjct: 1191 -TLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249
Query: 474 AIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSP-TAPKKKSLLL 532
+ P+ A AA +P + S +P S P P P AVS P + +
Sbjct: 1250 TLEEPTSSA-AAVLTPEELS--------SPAASVPTPEEPASPAAAVSNLEEPASPAAAV 1300
Query: 533 PAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSGGKPEPVVTV 592
P P A+P + + PA+ +P +V P G+P V+
Sbjct: 1301 PTPEVAAIPAASVPTPEVPAIPAA--AVPPMEEVSPIGVPFLG--------------VSA 1344
Query: 593 RTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQ 639
T + E T S + KE D L+ KEVT G+
Sbjct: 1345 HTDSVPISEEGTPVLEEASSTGMWIKEDLDSLVFGIKEVTSTVLHGK 1391
Score = 44.7 bits (104), Expect = 4e-04
Identities = 100/439 (22%), Positives = 151/439 (34%), Gaps = 32/439 (7%)
Query: 425 VPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAP----SQKAPAVPAPSQKAPAIPAPSR 480
VPA + P G A A S+P APAV A A A +P A AI P
Sbjct: 909 VPAVTVSVPEGTAA---VAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPIT 965
Query: 481 KASAASASP-RKASAVPAPPQ-KTPPPSQKAPSVPTIPQKAV-SPTAPKKKSLLLPAPSQ 537
+ P A+ V AP + T P P P AV +P P + +P P +
Sbjct: 966 EEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEE 1025
Query: 538 KALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAV--LERSQSGGKPEPVVTVRTQ 595
P + + PA+ P + PT P AV E S P T
Sbjct: 1026 PTSPAAAVPPPEEPTSPAAAVPTPEE----PTS-PAAAVPTPEEPTSPAAAVPTPEEPTS 1080
Query: 596 ETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQGKLEDWAHWAKLEERS 655
V + SP + ++ + T E E+ A A +
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP-T 1139
Query: 656 PDLPGVRSKELEQRKRWVKAKELAVEGPSQEHSRPFSV--EALTLTKLMITANSKEQPSK 713
P+ P + + + A +AV P + S +V A + + + A +E S
Sbjct: 1140 PEEPAFPAPAVPTPEESASA-AVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198
Query: 714 SALVSLPSWLLATPQASATSMMASVPS--RPGQLSLLEGKPVVVREQPESHTWVKEGKRP 771
+A V P+ ++AT + TS ASVP+ P L+ P E+P S P
Sbjct: 1199 AASVPTPAAMVATLE-EFTSPAASVPTSEEPASLAAAVSNP----EEPTS----PAAAVP 1249
Query: 772 WGEMKEQPWGEMKEPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPLTASPWEDLRPSP 831
E + P VP +P S + + + P A P ++ P
Sbjct: 1250 TLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIP 1309
Query: 832 LSETLISKMEATARASQQP 850
+ ++ A A+ P
Sbjct: 1310 AASVPTPEVPAIPAAAVPP 1328
Score = 32.3 bits (72), Expect = 2.1
Identities = 46/148 (31%), Positives = 60/148 (40%), Gaps = 46/148 (31%)
Query: 356 SSAASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQKAPSGLVTSCKAPFL 415
SSAA+ L P LS+P +S+P E A P A S L
Sbjct: 1256 SSAAAVLTPEE----LSSPAASVPTPEEPASPAA------------AVSNL--------- 1290
Query: 416 VDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAI 475
+ PA PA++ P P +A PAAS P + PA+P A AVP P ++ I
Sbjct: 1291 -----EEPASPAAA-VPTPEVA---AIPAASVPTPEVPAIP-----AAAVP-PMEEVSPI 1335
Query: 476 PAPSRKASAASASPRKASAVPAPPQKTP 503
P SA + S VP + TP
Sbjct: 1336 GVPFLGVSAHTDS------VPISEEGTP 1357
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,332,751
Number of Sequences: 37866
Number of extensions: 2729868
Number of successful extensions: 43100
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 616
Number of HSP's successfully gapped in prelim test: 2031
Number of HSP's that attempted gapping in prelim test: 15147
Number of HSP's gapped (non-prelim): 12993
length of query: 922
length of database: 18,247,518
effective HSP length: 112
effective length of query: 810
effective length of database: 14,006,526
effective search space: 11345286060
effective search space used: 11345286060
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.