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Search of human proteins with 223890201
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo
sapiens]
(444 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo s... 903 0.0
gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo sap... 880 0.0
gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo s... 766 0.0
gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo s... 553 e-157
gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo s... 410 e-115
gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo sa... 340 2e-93
gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo sa... 296 2e-80
gi|88702791 mouse double minute 4 homolog [Homo sapiens] 217 1e-56
gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo sa... 193 3e-49
gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo sa... 167 2e-41
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 47 3e-05
gi|223278368 neuralized-like [Homo sapiens] 42 0.001
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa... 41 0.002
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap... 41 0.002
gi|87299628 biorientation of chromosomes in cell division 1-like... 40 0.003
gi|217416388 neuralized homolog 1B [Homo sapiens] 39 0.007
gi|58743365 ring finger protein 157 [Homo sapiens] 39 0.007
gi|38788243 myosin regulatory light chain interacting protein [H... 39 0.007
gi|32698714 hypothetical protein LOC284058 [Homo sapiens] 39 0.009
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap... 38 0.016
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens] 37 0.028
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens] 37 0.028
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 37 0.028
gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1 ... 37 0.028
gi|210032580 SET domain containing 1B [Homo sapiens] 37 0.028
gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo sa... 37 0.036
gi|47578107 delangin isoform B [Homo sapiens] 37 0.036
gi|47578105 delangin isoform A [Homo sapiens] 37 0.036
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 36 0.062
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 36 0.080
>gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo
sapiens]
Length = 444
Score = 903 bits (2333), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
Query: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
Sbjct: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
Query: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 180
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ
Sbjct: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 180
Query: 181 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQVTVYQAGESD 240
RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQVTVYQAGESD
Sbjct: 181 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQVTVYQAGESD 240
Query: 241 TDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKL 300
TDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKL
Sbjct: 241 TDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKL 300
Query: 301 ENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSS 360
ENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSS
Sbjct: 301 ENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSS 360
Query: 361 QEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKK 420
QEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKK
Sbjct: 361 QEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKK 420
Query: 421 LKKRNKPCPVCRQPIQMIVLTYFP 444
LKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 421 LKKRNKPCPVCRQPIQMIVLTYFP 444
>gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo
sapiens]
Length = 497
Score = 880 bits (2275), Expect = 0.0
Identities = 444/491 (90%), Positives = 444/491 (90%), Gaps = 47/491 (9%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 66
Query: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
Sbjct: 67 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 126
Query: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 180
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ
Sbjct: 127 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 186
Query: 181 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGV------------ 228
RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGV
Sbjct: 187 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS 246
Query: 229 -----------------------------------YQVTVYQAGESDTDSFEEDPEISLA 253
YQVTVYQAGESDTDSFEEDPEISLA
Sbjct: 247 VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLA 306
Query: 254 DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP 313
DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP
Sbjct: 307 DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP 366
Query: 314 DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ 373
DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ
Sbjct: 367 DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ 426
Query: 374 DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ 433
DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ
Sbjct: 427 DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ 486
Query: 434 PIQMIVLTYFP 444
PIQMIVLTYFP
Sbjct: 487 PIQMIVLTYFP 497
>gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo
sapiens]
Length = 452
Score = 766 bits (1979), Expect = 0.0
Identities = 399/491 (81%), Positives = 399/491 (81%), Gaps = 92/491 (18%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE
Sbjct: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE-------- 58
Query: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
KIYTMIYRNLVVVNQQESSDSGT
Sbjct: 59 -------------------------------------KIYTMIYRNLVVVNQQESSDSGT 81
Query: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 180
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ
Sbjct: 82 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 141
Query: 181 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGV------------ 228
RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGV
Sbjct: 142 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS 201
Query: 229 -----------------------------------YQVTVYQAGESDTDSFEEDPEISLA 253
YQVTVYQAGESDTDSFEEDPEISLA
Sbjct: 202 VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLA 261
Query: 254 DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP 313
DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP
Sbjct: 262 DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP 321
Query: 314 DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ 373
DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ
Sbjct: 322 DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ 381
Query: 374 DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ 433
DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ
Sbjct: 382 DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ 441
Query: 434 PIQMIVLTYFP 444
PIQMIVLTYFP
Sbjct: 442 PIQMIVLTYFP 452
>gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo
sapiens]
Length = 442
Score = 553 bits (1425), Expect = e-157
Identities = 276/327 (84%), Positives = 279/327 (85%), Gaps = 47/327 (14%)
Query: 165 ISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDL 224
+++ EENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDL
Sbjct: 116 VNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDL 175
Query: 225 DAGV-----------------------------------------------YQVTVYQAG 237
DAGV YQVTVYQAG
Sbjct: 176 DAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAG 235
Query: 238 ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEK 297
ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEK
Sbjct: 236 ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEK 295
Query: 298 AKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSII 357
AKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSII
Sbjct: 296 AKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSII 355
Query: 358 YSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC 417
YSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC
Sbjct: 356 YSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC 415
Query: 418 AKKLKKRNKPCPVCRQPIQMIVLTYFP 444
AKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 416 AKKLKKRNKPCPVCRQPIQMIVLTYFP 442
>gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo
sapiens]
Length = 295
Score = 410 bits (1055), Expect = e-115
Identities = 196/211 (92%), Positives = 198/211 (93%), Gaps = 4/211 (1%)
Query: 234 YQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGE 293
Y E + +ED E DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGE
Sbjct: 89 YSLSEEGQELSDEDDE----DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGE 144
Query: 294 ISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTS 353
ISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTS
Sbjct: 145 ISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTS 204
Query: 354 SSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMA 413
SSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMA
Sbjct: 205 SSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMA 264
Query: 414 CFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 444
CFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 265 CFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 295
Score = 105 bits (263), Expect = 6e-23
Identities = 53/54 (98%), Positives = 53/54 (98%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 54
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE L
Sbjct: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDL 54
>gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo
sapiens]
Length = 249
Score = 340 bits (872), Expect = 2e-93
Identities = 171/174 (98%), Positives = 172/174 (98%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 66
Query: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
Sbjct: 67 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 126
Query: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 174
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE D+
Sbjct: 127 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK 180
Score = 168 bits (425), Expect = 1e-41
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 337 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 396
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Query: 397 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 444
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
>gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo
sapiens]
Length = 172
Score = 296 bits (759), Expect = 2e-80
Identities = 148/153 (96%), Positives = 149/153 (97%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 66
Query: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
Sbjct: 67 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 126
Query: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLV 153
SVSENRCHLEGGSDQKDLVQELQEEKP + V
Sbjct: 127 SVSENRCHLEGGSDQKDLVQELQEEKPKTKKRV 159
>gi|88702791 mouse double minute 4 homolog [Homo sapiens]
Length = 490
Score = 217 bits (553), Expect = 1e-56
Identities = 139/468 (29%), Positives = 226/468 (48%), Gaps = 59/468 (12%)
Query: 28 VRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFG 87
VRPK LLK+L + GAQ + +T+KEV+ YLGQYIM K+LYD+++QH+VYC DLLG+L G
Sbjct: 27 VRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLG 86
Query: 88 VPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKP 147
SFSVK+ +Y M+ +NLV + ++D+ +++ + H Q L Q +E
Sbjct: 87 RQSFSVKDPSPLYDMLRKNLVTL-ATATTDAAQTLALAQDHSMDIPSQDQLKQSAEESST 145
Query: 148 SSSHLVSR--PSTSSRRRAISETEENSDELSGERQRKRHKSD------------------ 187
S P+ + + E+ D + Q + + D
Sbjct: 146 SRKRTTEDDIPTLPTSEHKCIHSREDEDLIENLAQDETSRLDLGFEEWDVAGLPWWFLGN 205
Query: 188 -----------SISLSFDESLALCVIREICCE----RSSSSESTG---------TPSNPD 223
S L ++ + ++ + + S SE G T +
Sbjct: 206 LRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEAADTEQTSE 265
Query: 224 LDAGVYQVTVYQAGESD------TDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWA 277
V V + G++D + S + D E++ D W+CT C + N P +C RCWA
Sbjct: 266 EVGKVSDKKVIEVGKNDDLEDSKSLSDDTDVEVTSEDEWQCTECKKFNSPSKRYCFRCWA 325
Query: 278 LRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTI---VNDSRESCVEENDDK 334
LR++W D K +S + EG DVPDC++TI V +++ +++ + K
Sbjct: 326 LRKDWY-SDCSKLTHSLSTSDITAIPEKENEGNDVPDCRRTISAPVVRPKDAYIKKENSK 384
Query: 335 ITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVIC 394
+ S E D + S S I S E + + T E++E N ++PC +C
Sbjct: 385 LFDPCNSVEFLDLAHSSESQETISSMGEQLDNLSEQRTDT--ENMEDCQ--NLLKPCSLC 440
Query: 395 QGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTY 442
+ RP++G I+HG+TGHL+ CF CA++LKK CP+C++ IQ+++ +
Sbjct: 441 EKRPRDGNIIHGRTGHLVTCFHCARRLKKAGASCPICKKEIQLVIKVF 488
>gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo
sapiens]
Length = 179
Score = 193 bits (490), Expect = 3e-49
Identities = 95/98 (96%), Positives = 96/98 (97%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 66
Query: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRK 98
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE +
Sbjct: 67 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEFER 104
Score = 175 bits (444), Expect = 6e-44
Identities = 81/81 (100%), Positives = 81/81 (100%)
Query: 364 VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK 423
VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK
Sbjct: 99 VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK 158
Query: 424 RNKPCPVCRQPIQMIVLTYFP 444
RNKPCPVCRQPIQMIVLTYFP
Sbjct: 159 RNKPCPVCRQPIQMIVLTYFP 179
>gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo
sapiens]
Length = 111
Score = 167 bits (423), Expect = 2e-41
Identities = 84/95 (88%), Positives = 88/95 (92%), Gaps = 1/95 (1%)
Query: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 66
Query: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 95
IMTKRLYDEKQQHIVYCSND +LF + S++E
Sbjct: 67 IMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 47.0 bits (110), Expect = 3e-05
Identities = 62/275 (22%), Positives = 99/275 (36%), Gaps = 27/275 (9%)
Query: 111 NQQESSDSGTSV-SENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETE 169
N +SSDS S S N SD D + +SS S S SS S++
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS-SDSSNSSDSSDSSDSS 848
Query: 170 ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVY 229
+ SD S R + SDS S + + E S+SS+S+ + ++ D D+
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS-- 906
Query: 230 QVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGK 289
+S S D S S + N S+ +
Sbjct: 907 --------DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS-------------DSS 945
Query: 290 DKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQ 349
D + S + NS+ + D D + +DS S + + +S S +S + S
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 350 PSTS--SSIIYSSQEDVKEFEREETQDKEESVESS 382
S S SS +S + + + D +S +SS
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Score = 45.8 bits (107), Expect = 8e-05
Identities = 51/272 (18%), Positives = 105/272 (38%), Gaps = 6/272 (2%)
Query: 111 NQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE 170
+ S S T+ S++ + G+D D + + SS S SS S++ +
Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSD------SDSSDSSNSSDSSD 565
Query: 171 NSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQ 230
+SD S + S S S D S + + S SS+S+ + + D
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 231 VTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKD 290
+ ++ SD+DS + + + +D + ++ + S + + + +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 291 KGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQP 350
+ S+ + NS+++ + D D + +DS S ++D + S + S
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 351 STSSSIIYSSQEDVKEFEREETQDKEESVESS 382
S+ SS S + ++ D +S +SS
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Score = 45.8 bits (107), Expect = 8e-05
Identities = 53/274 (19%), Positives = 102/274 (37%), Gaps = 14/274 (5%)
Query: 111 NQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE 170
+ S+ S +S S N SD D + +SS S S SS S++ +
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS-SNSSDSSDSSNSSDSSD 843
Query: 171 NSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQ 230
+SD G ++SDS + S + + S S+ES+ + + D
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD------- 896
Query: 231 VTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKD 290
+ SD+DS + +D + +E + + + + + +
Sbjct: 897 ----SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 291 KGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQP 350
+ S + NS+ + + + +DS +S + + +S S +S D S
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Query: 351 STS--SSIIYSSQEDVKEFEREETQDKEESVESS 382
S S SS +S + + ++ D +S +SS
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046
Score = 45.1 bits (105), Expect = 1e-04
Identities = 56/273 (20%), Positives = 99/273 (36%), Gaps = 5/273 (1%)
Query: 111 NQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE 170
+ +SSDS S S++ E S D + + S S S S SS S++ +
Sbjct: 612 DSSDSSDSSDSKSDSS-KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670
Query: 171 NSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQ 230
+SD S S S D S + S SS+S+ + ++ D+
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730
Query: 231 VTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKD 290
+ + +DS + + +D + + + S + + N D
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN---SSDSND 787
Query: 291 KGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQP 350
S+ + NS+ + D D + +DS S N + +S S +S D S
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 351 STSSSIIYSSQED-VKEFEREETQDKEESVESS 382
S S S++ D + ++ D S +SS
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
>gi|223278368 neuralized-like [Homo sapiens]
Length = 574
Score = 42.0 bits (97), Expect = 0.001
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 382 SLPLNAIEP--------CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKR-NKPCPVCR 432
SLP + + P C IC + I GH+ C+ C +LKK + CP+CR
Sbjct: 504 SLPESPVTPGLGQWSDECTICYEHAVDTVIY--TCGHMCLCYACGLRLKKALHACCPICR 561
Query: 433 QPIQMIVLTY 442
+PI+ I+ TY
Sbjct: 562 RPIKDIIKTY 571
>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 361 QEDVKEFEREETQDKEESVESSLP-LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAK 419
Q+D+K E+ D VE L L C +C K IV GHL+ C CA
Sbjct: 528 QQDIKYIPTEDVSDLP--VEEQLRRLQEERTCKVCMD--KEVSIVFIPCGHLVVCKDCAP 583
Query: 420 KLKKRNKPCPVCRQPIQMIVLTY 442
L+K CP+CR I+ V T+
Sbjct: 584 SLRK----CPICRSTIKGTVRTF 602
>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 361 QEDVKEFEREETQDKEESVESSLP-LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAK 419
Q+D+K E+ D VE L L C +C K IV GHL+ C CA
Sbjct: 528 QQDIKYIPTEDVSDLP--VEEQLRRLQEERTCKVCMD--KEVSIVFIPCGHLVVCKDCAP 583
Query: 420 KLKKRNKPCPVCRQPIQMIVLTY 442
L+K CP+CR I+ V T+
Sbjct: 584 SLRK----CPICRSTIKGTVRTF 602
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 26/159 (16%)
Query: 95 EHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVS 154
E K YT + NL+++N+ +S S+QK+ + E+KP S+
Sbjct: 288 EEIKNYTKEHNNLILLNKDVQQES--------------SEQKNKSTDKGEKKPDSNEKGE 333
Query: 155 RPSTSSRRRAI----SETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERS 210
R + S+ E++ ++ E+Q K + +S+ L +++ E E
Sbjct: 334 RKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDF 393
Query: 211 SSSESTGTPSNPDLDAGVYQVTVYQAGESDTDSFEEDPE 249
S +S D+D G+ +TV SD SFEED E
Sbjct: 394 SLIDS-------DVD-GLTDITVSSVHTSDLSSFEEDTE 424
>gi|217416388 neuralized homolog 1B [Homo sapiens]
Length = 555
Score = 39.3 bits (90), Expect = 0.007
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 342 QESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRP--- 398
Q S + PS S S + F ++ ES + P + + P V P
Sbjct: 436 QSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEP 495
Query: 399 ---KNG-CIV--HGKT-------GHLMACFTCAKKLKKRNKPC-PVCRQPIQMIVLTYFP 444
KNG C V G+ GH+ C +C +LK++ + C P+CR+PI+ ++ Y P
Sbjct: 496 AGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP 555
>gi|58743365 ring finger protein 157 [Homo sapiens]
Length = 679
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 349 QPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKT 408
Q + Y QE + TQD + + E + N+ E CV+C ++ I+ +
Sbjct: 237 QKQVVDGVSYLLQEIYGIENKYNTQDSKVA-EDEVSDNSAE-CVVCLSDVRDTLILPCR- 293
Query: 409 GHLMACFTCAKKLKKRNKPCPVCRQPIQMIV 439
HL C TCA L+ + CP+CR P + ++
Sbjct: 294 -HLCLCNTCADTLRYQANNCPICRLPFRALL 323
>gi|38788243 myosin regulatory light chain interacting protein [Homo
sapiens]
Length = 445
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
Query: 310 FDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQ-PSTSSSIIYSSQEDVKEFE 368
FD+ K + + +R + N + S++ +S +S S+ SS+ SS E + +
Sbjct: 313 FDIKRTSKEVYDHARRALY--NAGVVDLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQ 370
Query: 369 REETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPC 428
Q+K ++ ++ C++C N GH + C +CA +L+ C
Sbjct: 371 TRVLQEKLRKLKEAML------CMVCCEEEINSTFC--PCGHTVCCESCAAQLQS----C 418
Query: 429 PVCRQPIQMIVLTYFP 444
PVCR ++ + Y P
Sbjct: 419 PVCRSRVEHVQHVYLP 434
>gi|32698714 hypothetical protein LOC284058 [Homo sapiens]
Length = 1105
Score = 38.9 bits (89), Expect = 0.009
Identities = 74/313 (23%), Positives = 121/313 (38%), Gaps = 70/313 (22%)
Query: 128 HLEGGSDQKDL--VQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHK 185
H GG +K L + L+ +P S +++R + ++ R+A SET S+ LS K
Sbjct: 319 HQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASET-TTSEGLSNFL-----K 372
Query: 186 SDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQVTVYQAGESDTDSFE 245
S+SIS + A + C E++ S+ T + S GESD
Sbjct: 373 SNSISEELERFTASGIANLRCSEQAFDSDVTDSSS---------------GGESDI---- 413
Query: 246 EDPEISLADYWKCTSCNEMNPPLPSHCNRCWAL-------RENWLPEDKGKDKGEISEKA 298
E+ E++ AD + + PL WA R NWL + I ++
Sbjct: 414 EEEELTRAD------PEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQT 467
Query: 299 KLENSTQAEEGF----DVPDCKKT---IVNDSRESCVEENDDKITQASQSQESEDYSQP- 350
+ +A +G +VP + T + S E + DK+ + S SQ E++ P
Sbjct: 468 DIYKQIRANKGLIVLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIE-SVSQPLENHGAPI 526
Query: 351 --------STSS--------SIIYSSQEDVKEFEREETQDKEESVESSLPLNAIE----- 389
ST S +I + Q + + ++ D EE + LN +
Sbjct: 527 IGHISESLSTKSCGALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDG 586
Query: 390 PCVICQGRPKNGC 402
CV + RP C
Sbjct: 587 TCVAARTRPVLSC 599
>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
sapiens]
Length = 618
Score = 38.1 bits (87), Expect = 0.016
Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 26/146 (17%)
Query: 297 KAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSI 356
K K + QA E D K + ++C++E D + Y ++
Sbjct: 497 KQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTL-----------YKNLFVDKNM 545
Query: 357 IYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFT 416
Y EDV EE + L C +C K +V GHL+ C
Sbjct: 546 KYIPTEDVSGLSLEEQLRR---------LQEERTCKVCMD--KEVSVVFIPCGHLVVCQE 594
Query: 417 CAKKLKKRNKPCPVCRQPIQMIVLTY 442
CA L+K CP+CR I+ V T+
Sbjct: 595 CAPSLRK----CPICRGIIKGTVRTF 616
>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
Length = 373
Score = 37.4 bits (85), Expect = 0.028
Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 17/75 (22%)
Query: 360 SQEDVKEF-EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCA 418
++E+ K + ER + QD+E+ + ++A+ CV+ + GH++ C C
Sbjct: 304 NEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLE------------CGHMVTCTKCG 351
Query: 419 KKLKKRNKPCPVCRQ 433
K++ + CP+CRQ
Sbjct: 352 KRMSE----CPICRQ 362
>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
Length = 372
Score = 37.4 bits (85), Expect = 0.028
Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 17/75 (22%)
Query: 360 SQEDVKEF-EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCA 418
++E+ K + ER + QD+E+ + ++A+ CV+ + GH++ C C
Sbjct: 303 NEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLE------------CGHMVTCTKCG 350
Query: 419 KKLKKRNKPCPVCRQ 433
K++ + CP+CRQ
Sbjct: 351 KRMSE----CPICRQ 361
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 37.4 bits (85), Expect = 0.028
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 113 QESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENS 172
++ SGT S+ + L+ SD+KD + EK +SR +S + A+ T
Sbjct: 220 KDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGE--ISRTVSSQKPPALKATSVKE 277
Query: 173 DELSGERQRKRHKSDSISLSFDESLALCVIRE 204
D + + K+ S ++SFD+ L R+
Sbjct: 278 DSVLNIAREKKDGEKSRTVSFDQPPGLKATRD 309
>gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1
[Homo sapiens]
Length = 352
Score = 37.4 bits (85), Expect = 0.028
Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 18/85 (21%)
Query: 365 KEFEREETQ-------DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC 417
+EF+ E Q + ES++S+ CV+C K+ V + GH+ +C C
Sbjct: 277 EEFQEHEAQLLSRAKPEDRESLKSA--------CVVCLSSFKS--CVFLECGHVCSCTEC 326
Query: 418 AKKLKKRNKPCPVCRQPIQMIVLTY 442
+ L + K CP+CRQ I ++ Y
Sbjct: 327 YRALPEPKK-CPICRQAITRVIPLY 350
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 37.4 bits (85), Expect = 0.028
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Query: 286 DKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVE-ENDDKITQASQ-SQE 343
D G ++ E ++ + ST+ EE + + ++ +D + E ENDD+ T S+ S++
Sbjct: 1030 DSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK 1089
Query: 344 SEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESS 382
E S + SI+ S E E E+ + E S ESS
Sbjct: 1090 DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESS 1128
Score = 35.0 bits (79), Expect = 0.14
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 12/98 (12%)
Query: 285 EDKGKDKGEIS---EKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQS 341
+D D+ E E L +++ +EG + +IV E+ T +S+S
Sbjct: 1065 DDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEA---------TSSSES 1115
Query: 342 QESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESV 379
ES ++ S SS +E+V E EE +++EE V
Sbjct: 1116 SESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMV 1153
Score = 33.1 bits (74), Expect = 0.52
Identities = 27/114 (23%), Positives = 55/114 (48%), Gaps = 12/114 (10%)
Query: 279 RENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP----DCKKTIVNDSRESCVEENDDK 334
+E+ E + ++ E +E+ + E ++ D D + T ++++ E ++D++
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE 1097
Query: 335 IT--------QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVE 380
T +A+ S ES + S+ +SS SS ED +E E +++EE E
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEE 1151
Score = 31.6 bits (70), Expect = 1.5
Identities = 32/162 (19%), Positives = 72/162 (44%), Gaps = 23/162 (14%)
Query: 111 NQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPST---SSRRRAISE 167
++ E+ D T++SE EG SD+++ V + + ++S S S+ SS + S
Sbjct: 1072 DESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSS 1131
Query: 168 TEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAG 227
+E+ + ++ E + + + + ++ +ES+A + E+ P P +D+
Sbjct: 1132 SEDEEEVVAREEEEEEEEEEMVA---EESMASAGPEDF---EQDGEEAALAPGAPAVDS- 1184
Query: 228 VYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLP 269
+ + + + +T++ + S+ D PPLP
Sbjct: 1185 ---LGMEEEVDIETEAVAPEERPSMLD----------EPPLP 1213
>gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo
sapiens]
Length = 497
Score = 37.0 bits (84), Expect = 0.036
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
Query: 334 KITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ-DKEESVESSLP-LNAIEPC 391
KI + +Y + + ++Q+D + E +T KE S E L L + C
Sbjct: 391 KIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLC 450
Query: 392 VICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVC 431
IC R N IV GHL+ C CA+ + K CP+C
Sbjct: 451 KICMDR--NIAIVFVPCGHLVTCKQCAEAVDK----CPMC 484
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 37.0 bits (84), Expect = 0.036
Identities = 56/287 (19%), Positives = 107/287 (37%), Gaps = 31/287 (10%)
Query: 106 NLVVVNQQESSDSG----TSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSR 161
N V V QQ +S + TSV +N+ + S Q + E++ + + + R S R
Sbjct: 432 NQVPVLQQNTSVAAKQPQTSVVQNQQQI---SQQGPIYDEVELDALAEIERIERESAIER 488
Query: 162 RRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSN 221
R E ++ L K+ K DS + +S+ TG+ N
Sbjct: 489 ERFSKEVQDKDKPL------KKRKQDSYPQEAGGATG---------GNRPASQETGSTGN 533
Query: 222 PDLDAGVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSH--CNRCWALR 279
A + + ++QAG D+ + S+ + CN+ + +
Sbjct: 534 GSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTP 593
Query: 280 ENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQAS 339
EN K K E+S+ ++ ++ E P+ + + S E+ +E + T+
Sbjct: 594 ENHPETPKKKSDPELSKSEMKQSESRLAE--SKPNENRLVETKSSENKLETKVETQTEEL 651
Query: 340 QSQESEDYSQPSTSSSIIYSSQ-----EDVKEFEREETQDKEESVES 381
+ ES S+I+ Q D K + ++ + E+ +S
Sbjct: 652 KQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKS 698
Score = 32.3 bits (72), Expect = 0.89
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 130 EGGSDQ---KDLVQELQEEKPSSSHLVSRPSTSSRRRA----------ISETEENSDELS 176
+G DQ K+L EL E S+ L R + R+R+ IS E+N + +
Sbjct: 1040 KGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEA 1099
Query: 177 GERQRKRHKSD 187
E RKRHK D
Sbjct: 1100 FESSRKRHKKD 1110
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 37.0 bits (84), Expect = 0.036
Identities = 56/287 (19%), Positives = 107/287 (37%), Gaps = 31/287 (10%)
Query: 106 NLVVVNQQESSDSG----TSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSR 161
N V V QQ +S + TSV +N+ + S Q + E++ + + + R S R
Sbjct: 432 NQVPVLQQNTSVAAKQPQTSVVQNQQQI---SQQGPIYDEVELDALAEIERIERESAIER 488
Query: 162 RRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSN 221
R E ++ L K+ K DS + +S+ TG+ N
Sbjct: 489 ERFSKEVQDKDKPL------KKRKQDSYPQEAGGATG---------GNRPASQETGSTGN 533
Query: 222 PDLDAGVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSH--CNRCWALR 279
A + + ++QAG D+ + S+ + CN+ + +
Sbjct: 534 GSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTP 593
Query: 280 ENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQAS 339
EN K K E+S+ ++ ++ E P+ + + S E+ +E + T+
Sbjct: 594 ENHPETPKKKSDPELSKSEMKQSESRLAE--SKPNENRLVETKSSENKLETKVETQTEEL 651
Query: 340 QSQESEDYSQPSTSSSIIYSSQ-----EDVKEFEREETQDKEESVES 381
+ ES S+I+ Q D K + ++ + E+ +S
Sbjct: 652 KQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKS 698
Score = 32.3 bits (72), Expect = 0.89
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 130 EGGSDQ---KDLVQELQEEKPSSSHLVSRPSTSSRRRA----------ISETEENSDELS 176
+G DQ K+L EL E S+ L R + R+R+ IS E+N + +
Sbjct: 1040 KGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEA 1099
Query: 177 GERQRKRHKSD 187
E RKRHK D
Sbjct: 1100 FESSRKRHKKD 1110
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 36.2 bits (82), Expect = 0.062
Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 289 KDKGEISEKAKLENSTQAE---EGFDVPDCKKTIVNDSR-----------ESCVEENDDK 334
K KG +SE K+E + ++ E FDV + + + + R + E+++
Sbjct: 503 KFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMS 562
Query: 335 ITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIE 389
+ S +S ++ + I+ DVKE+ERE E SV++ L +E
Sbjct: 563 VPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVE 617
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 35.8 bits (81), Expect = 0.080
Identities = 54/254 (21%), Positives = 95/254 (37%), Gaps = 38/254 (14%)
Query: 118 SGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSG 177
S S ++R L+ + +++ + E S +S+P RR + +++E+S E
Sbjct: 271 SRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQP----RRDSKGDSQEDSKENLS 326
Query: 178 ERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVYQVTVYQAG 237
+ + + S S + +L+ +E E S NPD T Y
Sbjct: 327 QEESQNVDGPSSESSQEANLSS---QENSSESQEEVVSESRGDNPD------PTTSYVED 377
Query: 238 ESDTDSFEEDPEISL-----------ADYWKCTSCN--EMNPPLP------------SHC 272
+ D+DS EED +L AD S N E +P P SH
Sbjct: 378 QEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHS 437
Query: 273 NRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEEND 332
+ + E E+ D + S + NST+++ + K I +SR+ V+
Sbjct: 438 SSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYH 497
Query: 333 DKITQASQSQESED 346
+K + +D
Sbjct: 498 NKPIGDQDDNDCQD 511
Score = 35.0 bits (79), Expect = 0.14
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 279 RENWLPEDKGKDKG---EISEKAKL---ENSTQAEEGF------DVPDCKKTIVNDSRES 326
+EN E+ G E S++A L ENS++++E D PD + V D +S
Sbjct: 322 KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDS 381
Query: 327 CVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKE 376
E D T + ES + S SS + S+E + E E + +E
Sbjct: 382 DSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQE 431
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,059,033
Number of Sequences: 37866
Number of extensions: 871816
Number of successful extensions: 4357
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 206
Number of HSP's that attempted gapping in prelim test: 3868
Number of HSP's gapped (non-prelim): 599
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.