Guide to the Human Genome
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Name: KALRN Sequence: fasta or formatted (2986aa) NCBI GI: 148839466
Description:

kalirin, RhoGEF kinase isoform 1

Referenced in:

Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt prot [1663aa] kalirin, RhoGEF kinase isoform 2
alt prot [1289aa] kalirin, RhoGEF kinase isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1        181           3
 C cysteine            1.8         55           2
 D aspartate           5.8        172           2
 E glutamate           8.7        261           3
 F phenylalanine       3.4        102           2
 G glycine             4.7        139           2
 H histidine           3.2         95           3
 I isoleucine          5.2        155           2
 K lysine              6.7        200           3
 L leucine            10.6        317           3
 M methionine          1.9         56           2
 N asparagine          3.8        114           2
 P proline             4.2        126           3
 Q glutamine           6.3        189           4
 R arginine            5.2        155           3
 S serine              7.6        227           3
 T threonine           4.8        144           2
 V valine              6.1        183           2
 W tryptophan          1.4         41           1
 Y tyrosine            2.5         74           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.545   kalirin, RhoGEF kinase isoform 2 
TRIO                  0.544   triple functional domain (PTPRF interacting) 
KALRN                 0.425   kalirin, RhoGEF kinase isoform 3 
GEFT                  0.068   RhoA/RAC/CDC42 exchange factor isoform 1 
GEFT                  0.068   RhoA/RAC/CDC42 exchange factor isoform 3 
MYLK                  0.037   myosin light chain kinase isoform 1 
MYLK                  0.037   myosin light chain kinase isoform 2 
DAPK1                 0.036   death-associated protein kinase 1 
DAPK3                 0.035   death-associated protein kinase 3 
TTN                   0.035   titin isoform N2-A 
TTN                   0.035   titin isoform novex-2 
TTN                   0.035   titin isoform novex-1 
TTN                   0.035   titin isoform N2-B 
MCF2L                 0.035   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.035   MCF.2 cell line derived transforming sequence-like ...
MCF2                  0.034   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.034   MCF.2 cell line derived transforming sequence isofo...
SESTD1                0.034   SEC14 and spectrin domains 1 
DAPK2                 0.034   death-associated kinase 2 
STK17A                0.029   serine/threonine kinase 17a 
PLEKHG4B              0.029   pleckstrin homology domain containing, family G (wi...
OBSCN                 0.029   obscurin, cytoskeletal calmodulin and titin-interac...
STK17B                0.027   serine/threonine kinase 17B 
MYLK                  0.027   myosin light chain kinase isoform 3A 
MYLK                  0.027   myosin light chain kinase isoform 3B 
SPEG                  0.027   SPEG complex locus 
PLEKHG4               0.026   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.026   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.026   pleckstrin homology domain containing, family G (wi...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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