Guide to the Human Genome
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Name: FGD4 Sequence: fasta or formatted (766aa) NCBI GI: 198041928
Description:

FYVE, RhoGEF and PH domain containing 4

Referenced in:

Rho and Rac
Zinc Finger Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.7         51           2
 C cysteine            2.3         18           1
 D aspartate           4.8         37           2
 E glutamate          10.1         77           3
 F phenylalanine       2.7         21           1
 G glycine             4.7         36           2
 H histidine           2.6         20           2
 I isoleucine          4.7         36           2
 K lysine              8.2         63           3
 L leucine             9.5         73           3
 M methionine          2.6         20           1
 N asparagine          4.3         33           2
 P proline             5.1         39           2
 Q glutamine           5.1         39           2
 R arginine            4.6         35           3
 S serine              7.8         60           2
 T threonine           5.4         41           3
 V valine              5.1         39           2
 W tryptophan          1.0          8           1
 Y tyrosine            2.6         20           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   FYVE, RhoGEF and PH domain containing 4 
FGD1                  0.408   faciogenital dysplasia protein 
FGD2                  0.375   FYVE, RhoGEF and PH domain containing 2 
FGD3                  0.317   FYVE, RhoGEF and PH domain containing 3 
FGD3                  0.317   FYVE, RhoGEF and PH domain containing 3 
FGD6                  0.182   FYVE, RhoGEF and PH domain containing 6 
FGD5                  0.139   FYVE, RhoGEF and PH domain containing 5 
FARP2                 0.103   FERM, RhoGEF and pleckstrin domain protein 2 
FARP1                 0.092   FERM, RhoGEF, and pleckstrin domain protein 1 isoform...
PREX1                 0.057   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
ECT2                  0.051   epithelial cell transforming sequence 2 oncogene pro...
PREX2                 0.049   DEP domain containing 2 isoform b 
PREX2                 0.049   DEP domain containing 2 isoform a 
ARHGEF4               0.049   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.049   Rho guanine nucleotide exchange factor 4 isoform b [...
NGEF                  0.047   neuronal guanine nucleotide exchange factor isoform...
NGEF                  0.047   neuronal guanine nucleotide exchange factor isoform...
ITSN1                 0.047   intersectin 1 isoform ITSN-l 
ARHGEF17              0.045   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
PLEKHG2               0.044   common-site lymphoma/leukemia guanine nucleotide ex...
ARHGEF16              0.044   Rho guanine exchange factor 16 
SPATA13               0.043   spermatogenesis associated 13 
TRIO                  0.043   triple functional domain (PTPRF interacting) 
KALRN                 0.042   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.042   kalirin, RhoGEF kinase isoform 3 
PLEKHF2               0.042   phafin 2 
SGEF                  0.041   Src homology 3 domain-containing guanine nucleotide...
ARHGEF9               0.040   Cdc42 guanine exchange factor 9 
KALRN                 0.040   kalirin, RhoGEF kinase isoform 2 
ARHGEF10L             0.039   Rho guanine nucleotide exchange factor (GEF) 10-like...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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