Guide to the Human Genome
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Name: KALRN Sequence: fasta or formatted (1663aa) NCBI GI: 4504335
Description:

kalirin, RhoGEF kinase isoform 2

Referenced in:

Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt prot [2986aa] kalirin, RhoGEF kinase isoform 1
alt prot [1289aa] kalirin, RhoGEF kinase isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1        102           3
 C cysteine            1.4         23           2
 D aspartate           6.0         99           2
 E glutamate           9.5        158           2
 F phenylalanine       3.7         62           2
 G glycine             4.0         67           2
 H histidine           4.0         67           3
 I isoleucine          4.9         81           2
 K lysine              6.8        113           3
 L leucine            11.9        198           3
 M methionine          1.8         30           1
 N asparagine          3.4         56           2
 P proline             2.5         42           2
 Q glutamine           7.5        124           4
 R arginine            5.4         90           2
 S serine              6.7        112           3
 T threonine           4.6         77           2
 V valine              6.0         99           2
 W tryptophan          1.6         27           1
 Y tyrosine            2.2         36           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   kalirin, RhoGEF kinase isoform 2 
KALRN                 0.986   kalirin, RhoGEF kinase isoform 1 
TRIO                  0.784   triple functional domain (PTPRF interacting) 
GEFT                  0.062   RhoA/RAC/CDC42 exchange factor isoform 1 
GEFT                  0.062   RhoA/RAC/CDC42 exchange factor isoform 3 
SESTD1                0.062   SEC14 and spectrin domains 1 
MCF2                  0.061   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.061   MCF.2 cell line derived transforming sequence isofo...
MCF2L                 0.061   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.061   MCF.2 cell line derived transforming sequence-like ...
KALRN                 0.059   kalirin, RhoGEF kinase isoform 3 
PLEKHG4B              0.053   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.046   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.046   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.046   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.046   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.046   pleckstrin homology domain containing, family G (wit...
MCF2L2                0.044   Rho family guanine-nucleotide exchange factor 
OBSCN                 0.033   obscurin, cytoskeletal calmodulin and titin-interact...
OBSCN                 0.033   obscurin, cytoskeletal calmodulin and titin-interac...
PLEKHG1               0.031   pleckstrin homology domain containing, family G (wit...
PLEKHG2               0.026   common-site lymphoma/leukemia guanine nucleotide ex...
SPTAN1                0.024   spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...
SPTAN1                0.024   spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...
FLJ10357              0.023   hypothetical protein LOC55701 
SPTBN5                0.022   spectrin, beta, non-erythrocytic 5 
SPTA1                 0.021   spectrin, alpha, erythrocytic 1 
PREX2                 0.020   DEP domain containing 2 isoform b 
PREX2                 0.020   DEP domain containing 2 isoform a 
SPTBN1                0.019   spectrin, beta, non-erythrocytic 1 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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