BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|219842259 usherin isoform A [Homo sapiens] (1546 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|219842259 usherin isoform A [Homo sapiens] 3291 0.0 gi|219842266 usherin isoform B [Homo sapiens] 3284 0.0 gi|21264602 laminin alpha 5 [Homo sapiens] 394 e-109 gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 325 2e-88 gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 325 2e-88 gi|62868217 laminin, beta 3 precursor [Homo sapiens] 298 4e-80 gi|62868215 laminin, beta 3 precursor [Homo sapiens] 298 4e-80 gi|189083719 laminin, beta 3 precursor [Homo sapiens] 298 4e-80 gi|167614504 laminin, beta 1 precursor [Homo sapiens] 277 7e-74 gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 275 2e-73 gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 275 2e-73 gi|119703755 laminin, beta 2 precursor [Homo sapiens] 271 3e-72 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 264 6e-70 gi|143770880 laminin, beta 4 [Homo sapiens] 251 3e-66 gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 245 2e-64 gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 231 3e-60 gi|93204871 netrin 4 [Homo sapiens] 197 9e-50 gi|148613884 netrin 1 [Homo sapiens] 196 2e-49 gi|5453810 netrin 3 [Homo sapiens] 163 1e-39 gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 162 2e-39 gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 155 3e-37 gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 146 1e-34 gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 146 2e-34 gi|24308065 netrin 5 [Homo sapiens] 144 9e-34 gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 141 4e-33 gi|164414431 netrin G1 isoform 1 [Homo sapiens] 127 6e-29 gi|190014607 netrin G2 [Homo sapiens] 126 1e-28 gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 126 2e-28 gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 126 2e-28 gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 116 1e-25 >gi|219842259 usherin isoform A [Homo sapiens] Length = 1546 Score = 3291 bits (8533), Expect = 0.0 Identities = 1546/1546 (100%), Positives = 1546/1546 (100%) Query: 1 MNCPVLSLGSGFLFQVIEMLIFAYFASISLTESRGLFPRLENVGAFKKVSIVPTQAVCGL 60 MNCPVLSLGSGFLFQVIEMLIFAYFASISLTESRGLFPRLENVGAFKKVSIVPTQAVCGL Sbjct: 1 MNCPVLSLGSGFLFQVIEMLIFAYFASISLTESRGLFPRLENVGAFKKVSIVPTQAVCGL 60 Query: 61 PDRSTFCHSSAAAESIQFCTQRFCIQDCPYRSSHPTYTALFSAGLSSCITPDKNDLHPNA 120 PDRSTFCHSSAAAESIQFCTQRFCIQDCPYRSSHPTYTALFSAGLSSCITPDKNDLHPNA Sbjct: 61 PDRSTFCHSSAAAESIQFCTQRFCIQDCPYRSSHPTYTALFSAGLSSCITPDKNDLHPNA 120 Query: 121 HSNSASFIFGNHKSCFSSPPSPKLMASFTLAVWLKPEQQGVMCVIEKTVDGQIVFKLTIS 180 HSNSASFIFGNHKSCFSSPPSPKLMASFTLAVWLKPEQQGVMCVIEKTVDGQIVFKLTIS Sbjct: 121 HSNSASFIFGNHKSCFSSPPSPKLMASFTLAVWLKPEQQGVMCVIEKTVDGQIVFKLTIS 180 Query: 181 EKETMFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGVEKDHTPFNAR 240 EKETMFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGVEKDHTPFNAR Sbjct: 181 EKETMFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGVEKDHTPFNAR 240 Query: 241 TLSGSITDFASGTVQIGQSLNGLEQFVGRMQDFRLYQVALTNREILEVFSGDLLRLHAQS 300 TLSGSITDFASGTVQIGQSLNGLEQFVGRMQDFRLYQVALTNREILEVFSGDLLRLHAQS Sbjct: 241 TLSGSITDFASGTVQIGQSLNGLEQFVGRMQDFRLYQVALTNREILEVFSGDLLRLHAQS 300 Query: 301 HCRCPGSHPRVHPLAQRYCIPNDAGDTADNRVSRLNPEAHPLSFVNDNDVGTSWVSNVFT 360 HCRCPGSHPRVHPLAQRYCIPNDAGDTADNRVSRLNPEAHPLSFVNDNDVGTSWVSNVFT Sbjct: 301 HCRCPGSHPRVHPLAQRYCIPNDAGDTADNRVSRLNPEAHPLSFVNDNDVGTSWVSNVFT 360 Query: 361 NITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG 420 NITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG Sbjct: 361 NITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG 420 Query: 421 AFGMKNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFV 480 AFGMKNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFV Sbjct: 421 AFGMKNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFV 480 Query: 481 KATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ 540 KATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ Sbjct: 481 KATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ 540 Query: 541 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG 600 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG Sbjct: 541 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG 600 Query: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG Sbjct: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 Query: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKAN 720 QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKAN Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKAN 720 Query: 721 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780 Query: 781 RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNN 840 RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNN Sbjct: 781 RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNN 840 Query: 841 SFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC 900 SFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC Sbjct: 841 SFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC 900 Query: 901 ECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN 960 ECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN Sbjct: 901 ECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN 960 Query: 961 HICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020 HICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ Sbjct: 961 HICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020 Query: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSP 1080 CFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSP Sbjct: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSP 1080 Query: 1081 NAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVT 1140 NAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVT Sbjct: 1081 NAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVT 1140 Query: 1141 YKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEG 1200 YKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEG Sbjct: 1141 YKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEG 1200 Query: 1201 HETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELH 1260 HETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELH Sbjct: 1201 HETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELH 1260 Query: 1261 VEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPP 1320 VEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPP Sbjct: 1261 VEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPP 1320 Query: 1321 QTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNI 1380 QTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNI Sbjct: 1321 QTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNI 1380 Query: 1381 SWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIY 1440 SWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIY Sbjct: 1381 SWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIY 1440 Query: 1441 EFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIY 1500 EFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIY Sbjct: 1441 EFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIY 1500 Query: 1501 QLERRESSLPALMTTMMKGIRFIGNGYCKFPSSTHPVNTDFTGKCV 1546 QLERRESSLPALMTTMMKGIRFIGNGYCKFPSSTHPVNTDFTGKCV Sbjct: 1501 QLERRESSLPALMTTMMKGIRFIGNGYCKFPSSTHPVNTDFTGKCV 1546 >gi|219842266 usherin isoform B [Homo sapiens] Length = 5202 Score = 3284 bits (8515), Expect = 0.0 Identities = 1543/1543 (100%), Positives = 1543/1543 (100%) Query: 1 MNCPVLSLGSGFLFQVIEMLIFAYFASISLTESRGLFPRLENVGAFKKVSIVPTQAVCGL 60 MNCPVLSLGSGFLFQVIEMLIFAYFASISLTESRGLFPRLENVGAFKKVSIVPTQAVCGL Sbjct: 1 MNCPVLSLGSGFLFQVIEMLIFAYFASISLTESRGLFPRLENVGAFKKVSIVPTQAVCGL 60 Query: 61 PDRSTFCHSSAAAESIQFCTQRFCIQDCPYRSSHPTYTALFSAGLSSCITPDKNDLHPNA 120 PDRSTFCHSSAAAESIQFCTQRFCIQDCPYRSSHPTYTALFSAGLSSCITPDKNDLHPNA Sbjct: 61 PDRSTFCHSSAAAESIQFCTQRFCIQDCPYRSSHPTYTALFSAGLSSCITPDKNDLHPNA 120 Query: 121 HSNSASFIFGNHKSCFSSPPSPKLMASFTLAVWLKPEQQGVMCVIEKTVDGQIVFKLTIS 180 HSNSASFIFGNHKSCFSSPPSPKLMASFTLAVWLKPEQQGVMCVIEKTVDGQIVFKLTIS Sbjct: 121 HSNSASFIFGNHKSCFSSPPSPKLMASFTLAVWLKPEQQGVMCVIEKTVDGQIVFKLTIS 180 Query: 181 EKETMFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGVEKDHTPFNAR 240 EKETMFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGVEKDHTPFNAR Sbjct: 181 EKETMFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGVEKDHTPFNAR 240 Query: 241 TLSGSITDFASGTVQIGQSLNGLEQFVGRMQDFRLYQVALTNREILEVFSGDLLRLHAQS 300 TLSGSITDFASGTVQIGQSLNGLEQFVGRMQDFRLYQVALTNREILEVFSGDLLRLHAQS Sbjct: 241 TLSGSITDFASGTVQIGQSLNGLEQFVGRMQDFRLYQVALTNREILEVFSGDLLRLHAQS 300 Query: 301 HCRCPGSHPRVHPLAQRYCIPNDAGDTADNRVSRLNPEAHPLSFVNDNDVGTSWVSNVFT 360 HCRCPGSHPRVHPLAQRYCIPNDAGDTADNRVSRLNPEAHPLSFVNDNDVGTSWVSNVFT Sbjct: 301 HCRCPGSHPRVHPLAQRYCIPNDAGDTADNRVSRLNPEAHPLSFVNDNDVGTSWVSNVFT 360 Query: 361 NITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG 420 NITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG Sbjct: 361 NITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG 420 Query: 421 AFGMKNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFV 480 AFGMKNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFV Sbjct: 421 AFGMKNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFV 480 Query: 481 KATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ 540 KATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ Sbjct: 481 KATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ 540 Query: 541 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG 600 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG Sbjct: 541 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG 600 Query: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG Sbjct: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 Query: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKAN 720 QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKAN Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKAN 720 Query: 721 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780 Query: 781 RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNN 840 RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNN Sbjct: 781 RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNN 840 Query: 841 SFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC 900 SFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC Sbjct: 841 SFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC 900 Query: 901 ECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN 960 ECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN Sbjct: 901 ECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN 960 Query: 961 HICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020 HICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ Sbjct: 961 HICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020 Query: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSP 1080 CFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSP Sbjct: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSP 1080 Query: 1081 NAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVT 1140 NAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVT Sbjct: 1081 NAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVT 1140 Query: 1141 YKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEG 1200 YKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEG Sbjct: 1141 YKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEG 1200 Query: 1201 HETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELH 1260 HETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELH Sbjct: 1201 HETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELH 1260 Query: 1261 VEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPP 1320 VEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPP Sbjct: 1261 VEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPP 1320 Query: 1321 QTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNI 1380 QTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNI Sbjct: 1321 QTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNI 1380 Query: 1381 SWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIY 1440 SWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIY Sbjct: 1381 SWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIY 1440 Query: 1441 EFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIY 1500 EFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIY Sbjct: 1441 EFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIY 1500 Query: 1501 QLERRESSLPALMTTMMKGIRFIGNGYCKFPSSTHPVNTDFTG 1543 QLERRESSLPALMTTMMKGIRFIGNGYCKFPSSTHPVNTDFTG Sbjct: 1501 QLERRESSLPALMTTMMKGIRFIGNGYCKFPSSTHPVNTDFTG 1543 Score = 158 bits (399), Expect = 4e-38 Identities = 143/531 (26%), Positives = 218/531 (41%), Gaps = 87/531 (16%) Query: 1054 PFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFE--------------IYTT 1099 P Q P S+++ LSWS P +PN + Y ++R FE I T Sbjct: 4155 PDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFEGKAWGNQTIQADEKIVFT 4214 Query: 1100 EDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNL--TLSYI 1157 E + + DT L P+T+ Y I T N G T S +T PEG +SY+ Sbjct: 4215 EYNTERNTFMYNDTGLQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPEGLSPPVISYV 4274 Query: 1158 IPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEGHETSATIWNLVPFAKYD 1217 + + ++W +G I+ Y L + S++ + T L+PF+ Y Sbjct: 4275 -SMNPQKLLISWIPPEQSNGIIQSYRLQRNEMLYP---FSFDPVTFNYTDEELLPFSTYS 4330 Query: 1218 FSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNG----II 1273 +++QACTSGGC S P ++TT +A P +SPP + +S+T+++V WSPP NG + Sbjct: 4331 YALQACTSGGCSTSKPTSITTLEAAPSEVSPPDLWAVSATQMNVCWSPPTVQNGKITKYL 4390 Query: 1274 IRYE-----------LYMRRLRSTKE--------TTSEESRVFQSSGWL---------SP 1305 +RY+ L + L+ + T + S W SP Sbjct: 4391 VRYDNKESLAGQGLCLLVSHLQPYSQYNFSLVACTNGGCTASVSKSAWTMEALPENMDSP 4450 Query: 1306 HSFVESAN--ENALKPPQT--------------MTTITGLE---------PYTKYEFRVL 1340 V + E KPP+ TGLE P +Y + V Sbjct: 4451 TLQVTGSESIEITWKPPRNPNGQIRSYELRRDGTIVYTGLETRYRDFTLTPGVEYSYTVT 4510 Query: 1341 AVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDIN 1400 A N G + S V +RT SAP M PP + + ++W+ P T G ++ Y Sbjct: 4511 ASNSQGGILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVR--TNGDIINY--T 4566 Query: 1401 MLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAG 1460 + + ++ + H + + SY V LKP+ YE I C ++GC +S Sbjct: 4567 LFIRELFERETKIIHINTTHNSFGMQ-SYIVNQLKPFHRYEIRIQACTTLGCASSDWTFI 4625 Query: 1461 QTLAAAPAQLRPP-----LVKGINSTTIHLKWFPPEELNGPSPIYQLERRE 1506 QT AP PP + G T+ L W P + NG Y+L RR+ Sbjct: 4626 QTPEIAPLMQPPPHLEVQMAPGGFQPTVSLLWTGPLQPNGKVLYYELYRRQ 4676 Score = 154 bits (390), Expect = 5e-37 Identities = 132/452 (29%), Positives = 200/452 (44%), Gaps = 46/452 (10%) Query: 1060 PRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYT 1119 PR + +S+ + L WS P+ PN Y L R+G ++ + Q F D +L P + Sbjct: 3688 PRHIIINSTTVELYWSLPEKPNGLVSQYQLSRNGNLLFLGGSEE----QNFTDKNLEPNS 3743 Query: 1120 KYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSG 1177 +Y+Y +E GS+ S +T PE I IG S+ + W + Sbjct: 3744 RYTYKLEVKTGGGSSASDDYIVQTPMSTPEEIYPPYNITVIGPYSIFVAWIPPGILIPEI 3803 Query: 1178 PIEKYIL----SCAPLAGGQPCVSYEGHETSATIWNLVPFAKYDFSVQACTSGGCLHSLP 1233 P+E +L S PLA GH S + NL PF +Y+ +QAC +G C S Sbjct: 3804 PVEYNVLLNDGSVTPLAFSV------GHHQSTLLENLTPFTQYEIRIQACQNGSCGVSSR 3857 Query: 1234 ITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTKETTSEE 1293 + V T +A P L+ P ++ + S + ++W PP + NGIII Y +Y R EE Sbjct: 3858 MFVKTPEAAPMDLNSPVLKALGSACIEIKWMPPEKPNGIIINYFIYRR-----PAGIEEE 3912 Query: 1294 SRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWV 1353 S +F W +E AL + M L P+T YE+RV A N GSV S W Sbjct: 3913 SVLFV---W----------SEGAL---EFMDEGDTLRPFTLYEYRVRACNSKGSVESLWS 3956 Query: 1354 SERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLSEQSPQQSIPM 1413 +T E+ P P S++S+ ++W KP G + Y ++ ++ P P Sbjct: 3957 LTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPES--PNGIISHY--RVVYQERPDD--PT 4010 Query: 1414 AFSQLLH--TAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAAAPAQLR 1471 S +H T K + GL+P+ Y + N G + S QTL ++P+ LR Sbjct: 4011 FNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGEILSPWTLIQTLESSPSGLR 4070 Query: 1472 PPLV-KGINSTTIHLKWFPPEELNGPSPIYQL 1502 +V + N + L+W P NG Y + Sbjct: 4071 NFIVEQKENGRALLLQWSEPMRTNGVIKTYNI 4102 Score = 150 bits (379), Expect = 9e-36 Identities = 117/455 (25%), Positives = 190/455 (41%), Gaps = 48/455 (10%) Query: 1054 PFQQPPPRGQVQSSSAINLSWSPPDSPN---AHWLTYSLLRDGFEIYTTEDQYPYSIQYF 1110 P P P Q S+ ++ L+W+ P+SPN +H+ R + + + ++++ Sbjct: 3965 PQDFPAPWAQATSAHSVLLNWTKPESPNGIISHYRVVYQERPDDPTFNSPTVHAFTVKGT 4024 Query: 1111 LDT----DLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVT 1166 L P+T Y + N G S +T P G ++ Sbjct: 4025 SHQAHLYGLEPFTTYRIGVVAANHAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALL 4084 Query: 1167 LTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEGHETSATIWNLVPFAKYDFSVQACTSG 1226 L W+ +G I+ Y + + Y G L PF Y +++ACT Sbjct: 4085 LQWSEPMRTNGVIKTYNIF------SDGFLEYSGLNRQFLFRRLDPFTLYTLTLEACTRA 4138 Query: 1227 GCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMR----R 1282 GC HS P + T +APP P + + ST + + WS P NG IIRYE+ R + Sbjct: 4139 GCAHSAPQPLWTDEAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFEGK 4198 Query: 1283 LRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAV 1342 + ++E VF E + M TGL+P+T+ E+++ Sbjct: 4199 AWGNQTIQADEKIVF---------------TEYNTERNTFMYNDTGLQPWTQCEYKIYTW 4243 Query: 1343 NMAGSVSSAWVSERTGESAPVFMIPP--SVFPLSSYSLNISWEKPADNVTRGKVVGYDIN 1400 N AG S+W RT ++ P + PP S ++ L ISW P + G + Y + Sbjct: 4244 NSAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPEQ--SNGIIQSYRL- 4300 Query: 1401 MLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAG 1460 Q + P +F + +YT E L P+ Y + + C S GC TS + Sbjct: 4301 ----QRNEMLYPFSFDPV-------TFNYTDEELLPFSTYSYALQACTSGGCSTSKPTSI 4349 Query: 1461 QTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNG 1495 TL AAP+++ PP + +++T +++ W PP NG Sbjct: 4350 TTLEAAPSEVSPPDLWAVSATQMNVCWSPPTVQNG 4384 Score = 147 bits (370), Expect = 1e-34 Identities = 121/463 (26%), Positives = 192/463 (41%), Gaps = 60/463 (12%) Query: 1058 PPPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLP 1117 P P+ S + N+SW+ P+ PN +Y L DG I+ + + Y F P Sbjct: 2245 PAPKAHSYSPDSFNVSWTEPEYPNGVITSYGLYLDGILIHNSSE-LSYRAYGFA-----P 2298 Query: 1118 YTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSG 1177 ++ +S+ ++ G V +T PEG + + ++ GS + W +G Sbjct: 2299 WSLHSFRVQACTAKGCALGPLVENRTLEAPPEGTVNV-FVKTQGSRKAHVRWEAPFRPNG 2357 Query: 1178 PIEKYILSCA-----PLAGGQPC-----VSYEGHETS--ATIWNLVPFAKYDFSVQACTS 1225 + +L P+ V Y G ET+ I LVPF Y V S Sbjct: 2358 LLTHSVLFTGIFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNS 2417 Query: 1226 GGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGI-IIRYELYMRRLR 1284 G L + PIT+ P + PP++ + T L V WS PA N RY+L MR Sbjct: 2418 QGSLITDPITIAMPPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPRYQLQMRSGD 2477 Query: 1285 STKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMT-TITGLEPYTKYEFRVLAVN 1343 ST H F+E + P +++ ++ L+PYT+Y FR++A N Sbjct: 2478 ST-------------------HGFLELFSN----PSASLSYEVSDLQPYTEYMFRLVASN 2514 Query: 1344 MAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLS 1403 GS S+W+ T E P ++PP + + S + ++W+ P + G + Y+I + Sbjct: 2515 GFGSAHSSWIPFMTAEDKPGPVVPPILLDVKSRMMLVTWQHP--RKSNGVITHYNIYL-- 2570 Query: 1404 EQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGC-VTSASGAGQT 1462 +L + TV L PY Y+F + C S GC ++ S T Sbjct: 2571 -----------HGRLYLRTPGNVTNCTVMHLHPYTAYKFQVEACTSKGCSLSPESQTVWT 2619 Query: 1463 LAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQLERR 1505 L AP + P + T++ + W PP NG + +ERR Sbjct: 2620 LPGAPEGIPSPELFSDTPTSVIISWQPPTHPNGLVENFTIERR 2662 Score = 146 bits (368), Expect = 2e-34 Identities = 122/463 (26%), Positives = 204/463 (44%), Gaps = 49/463 (10%) Query: 1059 PPRGQVQSSSAINLSWSPPDSPNAHWLT-YSL-LRDGFEIYTTEDQY--PYSIQYFLDTD 1114 PPR + +++ + WS P NA Y L +R G + + + P + + +D Sbjct: 2440 PPRLSSATPTSLQVVWSTPARNNAPGSPRYQLQMRSGDSTHGFLELFSNPSASLSYEVSD 2499 Query: 1115 LLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSN 1174 L PYT+Y + + +N GS S + + T P G + ++ + S + +TW Sbjct: 2500 LQPYTEYMFRLVASNGFGSAHSSWIPFMTAEDKP-GPVVPPILLDVKSRMMLVTWQHPRK 2558 Query: 1175 QSGPIEKYILSCAPLAGGQPCVSYEGHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLP 1233 +G I Y + G+ + G+ T+ T+ +L P+ Y F V+ACTS GC L Sbjct: 2559 SNGVITHYNI----YLHGRLYLRTPGNVTNCTVMHLHPYTAYKFQVEACTSKGCSLSPES 2614 Query: 1234 ITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTKETTSEE 1293 TV T P+ + P++ + T + + W PP NG++ + + RR++ +E T+ Sbjct: 2615 QTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNGLVENFTIE-RRVKGKEEVTT-- 2671 Query: 1294 SRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGSV-SSAW 1352 V ++++ + + L P+TKYE+RVL + G SSAW Sbjct: 2672 --------------LVTLPRSHSMR---FIDKTSALSPWTKYEYRVLMSTLHGGTNSSAW 2714 Query: 1353 VSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLSEQSPQQSIP 1412 V T S P + PP V L ++ ++W+ P + G ++ Y+I+M P I Sbjct: 2715 VEVTTRPSRPAGVQPPVVTVLEPDAVQVTWKPPL--IQNGDILSYEIHM-----PDPHIT 2767 Query: 1413 MAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSV-----GCVTSASGAGQTLAAAP 1467 + S LS V L P+ Y TI C+ GC S T P Sbjct: 2768 LT------NVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVP 2821 Query: 1468 AQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQLERRESSLP 1510 + P V ++ + + + W PP + NGP+ Y+L RR+ P Sbjct: 2822 QNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQP 2864 Score = 138 bits (348), Expect = 4e-32 Identities = 123/468 (26%), Positives = 193/468 (41%), Gaps = 64/468 (13%) Query: 1054 PFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYT-TEDQYPYSIQYFLD 1112 P P QV S +I ++W PP +PN +Y L RDG +YT E +Y D Sbjct: 4444 PENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYELRRDGTIVYTGLETRYR-------D 4496 Query: 1113 TDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTL 1172 L P +YSY + +N G S V +T P P G + + G + + W Sbjct: 4497 FTLTPGVEYSYTVTASNSQGGILSPLVKDRTSPSAPSG-MEPPKLQARGPQEILVNWDPP 4555 Query: 1173 SNQSGPIEKYILSCAPLAGGQPCVSYEG--HET----SATIWNLVPFAKYDFSVQACTSG 1226 +G I Y L L + + + H + S + L PF +Y+ +QACT+ Sbjct: 4556 VRTNGDIINYTLFIRELFERETKIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTL 4615 Query: 1227 GCLHSLPITVTTAQAPPQRLSPPKMQKISST-----ELHVEWSPPAELNGIIIRYELYMR 1281 GC S + T + P PP ++ + + + W+ P + NG ++ YELY R Sbjct: 4616 GCASSDWTFIQTPEIAPLMQPPPHLEVQMAPGGFQPTVSLLWTGPLQPNGKVLYYELYRR 4675 Query: 1282 RLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLA 1341 ++ +T+ S ++ S SF++S L P+T+YE++V A Sbjct: 4676 QI-ATQPRKSNPVLIYNGSST----SFIDSE----------------LLPFTEYEYQVWA 4714 Query: 1342 VNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINM 1401 VN AG S+W RTG + P + P+ +SS ++ P GK G Sbjct: 4715 VNSAGKAPSSWTWCRTGPAPPEGLRAPTFHVISSTQAVVNISAP------GKPNGI---- 4764 Query: 1402 LSEQSPQQSIPMAFSQLLHTAKS-----QELSYTVEGLKPYRIYEFTITLCNSVGCVTSA 1456 S+ FS H A++ T+ GL+ + Y + C C + Sbjct: 4765 -------VSLYRLFSSSAHGAETVLSEGMATQQTLHGLQAFTNYSIGVEACTCFNCCSKG 4817 Query: 1457 SGAG-QTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQLE 1503 A +T A P+ L P + + S T +W PP NG Y+L+ Sbjct: 4818 PTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYELQ 4865 Score = 137 bits (346), Expect = 6e-32 Identities = 121/456 (26%), Positives = 198/456 (43%), Gaps = 54/456 (11%) Query: 1058 PPPRGQVQS-SSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLL 1116 PP ++ + I L+W P N + Y LLR+G E + S+ + + Sbjct: 3504 PPTWTKIDNLEDTIVLNWRKPIQSNGPIIYYILLRNGIERFRGT-----SLSFSDKEGIQ 3558 Query: 1117 PYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQS 1176 P+ +YSY ++ V G S V T GVPE L S I + + ++ L+W+ + Sbjct: 3559 PFQEYSYQLKACTVAGCATSSKVVAATTQGVPESILPPS-ITALSAVALHLSWSVPEKSN 3617 Query: 1177 GPIEKYILSCAPLAGGQPCVSYEGHE-TSATIWNLVPFAKYDFSVQACTSGGCLHSLPIT 1235 G I++Y + G+ + + + T+ L P+ Y F++ ACTS GC S P Sbjct: 3618 GVIKEYQIRQV----GKGLIHTDTTDRRQHTVTGLQPYTNYSFTLTACTSAGCTSSEPFL 3673 Query: 1236 VTTAQAPPQRL-SPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTKETTSEES 1294 T QA P+ + P+ I+ST + + WS P + NG++ +Y+L S Sbjct: 3674 GQTLQAAPEGVWVTPRHIIINSTTVELYWSLPEKPNGLVSQYQL------------SRNG 3721 Query: 1295 RVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVS 1354 + G S +N T LEP ++Y +++ GS +S Sbjct: 3722 NLLFLGG---------SEEQN--------FTDKNLEPNSRYTYKLEVKTGGGSSASDDYI 3764 Query: 1355 ERTGESAPVFMIPP-SVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLSEQSPQQSIPM 1413 +T S P + PP ++ + YS+ ++W P + + + N+L P+ Sbjct: 3765 VQTPMSTPEEIYPPYNITVIGPYSIFVAWIPPGILIPE---IPVEYNVLLNDG--SVTPL 3819 Query: 1414 AFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAAAPAQLRPP 1473 AFS H S +E L P+ YE I C + C S+ +T AAP L P Sbjct: 3820 AFSVGHHQ------STLLENLTPFTQYEIRIQACQNGSCGVSSRMFVKTPEAAPMDLNSP 3873 Query: 1474 LVKGINSTTIHLKWFPPEELNGPSPIYQLERRESSL 1509 ++K + S I +KW PPE+ NG Y + RR + + Sbjct: 3874 VLKALGSACIEIKWMPPEKPNGIIINYFIYRRPAGI 3909 Score = 136 bits (343), Expect = 1e-31 Identities = 123/458 (26%), Positives = 188/458 (41%), Gaps = 68/458 (14%) Query: 1063 QVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYS 1122 Q ++ A+ L WS P N TY++ DGF Y+ ++ FL L P+T Y+ Sbjct: 4076 QKENGRALLLQWSEPMRTNGVIKTYNIFSDGFLEYSGLNRQ------FLFRRLDPFTLYT 4129 Query: 1123 YYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKY 1182 +E G S T P+ L + + + S SV L+W+ N +G I +Y Sbjct: 4130 LTLEACTRAGCAHSAPQPLWTDEAPPDSQLAPT-VHSVKSTSVELSWSEPVNPNGKIIRY 4188 Query: 1183 --ILSC--APLAGGQPCVSYE-------GHETSATIWN---LVPFAKYDFSVQACTSGGC 1228 I C G Q + E E + ++N L P+ + ++ + S G Sbjct: 4189 EVIRRCFEGKAWGNQTIQADEKIVFTEYNTERNTFMYNDTGLQPWTQCEYKIYTWNSAGH 4248 Query: 1229 LHSLPITVTTAQAPPQRLSPPKMQKISST--ELHVEWSPPAELNGIIIRYELYMRRLRST 1286 S V T QAPP+ LSPP + +S +L + W PP + NGII Y L Sbjct: 4249 TCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPEQSNGIIQSYRL-------- 4300 Query: 1287 KETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAG 1346 Q + L P SF P T L P++ Y + + A G Sbjct: 4301 -----------QRNEMLYPFSF---------DPVTFNYTDEELLPFSTYSYALQACTSGG 4340 Query: 1347 SVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLSEQS 1406 +S S T E+AP + PP ++ +S+ +N+ W P V GK+ Y + +++S Sbjct: 4341 CSTSKPTSITTLEAAPSEVSPPDLWAVSATQMNVCWSPPT--VQNGKITKYLVRYDNKES 4398 Query: 1407 PQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAAA 1466 Q L V L+PY Y F++ C + GC S S + T+ A Sbjct: 4399 ---------------LAGQGLCLLVSHLQPYSQYNFSLVACTNGGCTASVSKSAWTMEAL 4443 Query: 1467 PAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQLER 1504 P + P ++ S +I + W PP NG Y+L R Sbjct: 4444 PENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYELRR 4481 Score = 136 bits (343), Expect = 1e-31 Identities = 122/456 (26%), Positives = 196/456 (42%), Gaps = 48/456 (10%) Query: 1054 PFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDT 1113 P + PP S++ +N+ WSPP N +T L+R Y ++ L + Sbjct: 4356 PSEVSPPDLWAVSATQMNVCWSPPTVQNGK-ITKYLVR-----YDNKESLAGQGLCLLVS 4409 Query: 1114 DLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLS 1173 L PY++Y++ + G T SV+ + T +PE N+ + GS+S+ +TW Sbjct: 4410 HLQPYSQYNFSLVACTNGGCTASVSKSAWTMEALPE-NMDSPTLQVTGSESIEITWKPPR 4468 Query: 1174 NQSGPIEKYILSCAPLAGGQPCVSYEGHETSATIWNLVPFAKYDFSVQACTSGGCLHSLP 1233 N +G I Y L + Y G ET + L P +Y ++V A S G + S Sbjct: 4469 NPNGQIRSYELR------RDGTIVYTGLETRYRDFTLTPGVEYSYTVTASNSQGGILSPL 4522 Query: 1234 ITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTKETTSEE 1293 + T+ + P + PPK+Q E+ V W PP NG II Y L++R L + Sbjct: 4523 VKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHI 4582 Query: 1294 SRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWV 1353 + S G S + L+P+ +YE R+ A G SS W Sbjct: 4583 NTTHNSFGMQS-------------------YIVNQLKPFHRYEIRIQACTTLGCASSDWT 4623 Query: 1354 SERTGESAPVFMIPPSVFPLSS-----YSLNISWEKPADNVTRGKVVGYDI--NMLSEQS 1406 +T E AP+ PP + + ++++ W P GKV+ Y++ ++ Q Sbjct: 4624 FIQTPEIAPLMQPPPHLEVQMAPGGFQPTVSLLWTGPLQ--PNGKVLYYELYRRQIATQ- 4680 Query: 1407 PQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAAA 1466 P++S P+ L++ S S+ L P+ YE+ + NS G S+ +T A Sbjct: 4681 PRKSNPV----LIYNGSS--TSFIDSELLPFTEYEYQVWAVNSAGKAPSSWTWCRTGPAP 4734 Query: 1467 PAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQL 1502 P LR P I+ST + P + NG +Y+L Sbjct: 4735 PEGLRAPTFHVISSTQAVVNISAPGKPNGIVSLYRL 4770 Score = 135 bits (341), Expect = 2e-31 Identities = 125/480 (26%), Positives = 198/480 (41%), Gaps = 57/480 (11%) Query: 1049 GCSKTPFQQ------------PPPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLR--DGF 1094 GCS +P Q P P + +++ +SW PP PN +++ R G Sbjct: 2607 GCSLSPESQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNGLVENFTIERRVKGK 2666 Query: 1095 EIYTTEDQYP--YSIQYFLDTDLL-PYTKYSYYIETTNVHGSTRSVA-VTYKTKPGVPEG 1150 E TT P +S+++ T L P+TKY Y + + +HG T S A V T+P P G Sbjct: 2667 EEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVEVTTRPSRPAG 2726 Query: 1151 NLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEGHET---SATI 1207 + + + D+V +TW Q+G I Y + P ++ + S + Sbjct: 2727 -VQPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHMP-----DPHITLTNVTSAVLSQKV 2780 Query: 1208 WNLVPFAKYDFSVQACTSG-----GCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVE 1262 +L+PF Y ++ AC+ G GC SLP VTT PQ + P + +S + + + Sbjct: 2781 THLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLSVIPLSESYVVIS 2840 Query: 1263 WSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQT 1322 W PP++ NG +RYEL R+++ + E + W N Q Sbjct: 2841 WQPPSKPNGPNLRYELLRRKIQQPLASNPPE----DLNRW-----------HNIYSGTQW 2885 Query: 1323 MTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISW 1382 + GL +T YE+ + N G S V+ T P + L+ ++++ W Sbjct: 2886 LYEDKGLSRFTTYEYMLFVHNSVGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRW 2945 Query: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEF 1442 KP +G+V Y + S S ++L S + + LKP Y Sbjct: 2946 AKPTVQDLQGEVEYYTLFWSSATSNDS------LKILPDVNSHVIGH----LKPNTEYWI 2995 Query: 1443 TITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQL 1502 I++ N V + SA T P + PP V INST + + W P NG Y + Sbjct: 2996 FISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSI 3055 Score = 132 bits (332), Expect = 3e-30 Identities = 118/453 (26%), Positives = 190/453 (41%), Gaps = 48/453 (10%) Query: 1059 PPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTE--DQYPYSIQYFLDTDLL 1116 PP S+ A++LSWS P+ N Y + + G + T+ D+ +++ T L Sbjct: 3595 PPSITALSAVALHLSWSVPEKSNGVIKEYQIRQVGKGLIHTDTTDRRQHTV-----TGLQ 3649 Query: 1117 PYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQS 1176 PYT YS+ + G T S +T PEG I I S +V L W+ + Sbjct: 3650 PYTNYSFTLTACTSAGCTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVELYWSLPEKPN 3709 Query: 1177 GPIEKYILSCAPLAGGQPCVSYEGHETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITV 1236 G + +Y LS G E + T NL P ++Y + ++ T GG S V Sbjct: 3710 GLVSQYQLS----RNGNLLFLGGSEEQNFTDKNLEPNSRYTYKLEVKTGGGSSASDDYIV 3765 Query: 1237 TTAQAPPQRLSPP-KMQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTKETTSEESR 1295 T + P+ + PP + I + V W PP GI+I E Sbjct: 3766 QTPMSTPEEIYPPYNITVIGPYSIFVAWIPP----GILI-------------PEIPVEYN 3808 Query: 1296 VFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSE 1355 V + G ++P +F +++ L + L P+T+YE R+ A S+ + Sbjct: 3809 VLLNDGSVTPLAFSVGHHQSTL--------LENLTPFTQYEIRIQACQNGSCGVSSRMFV 3860 Query: 1356 RTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAF 1415 +T E+AP+ + P + L S + I W P G ++ Y I ++S+ + Sbjct: 3861 KTPEAAPMDLNSPVLKALGSACIEIKWMPPEK--PNGIIINYFIYRRPAGIEEESVLFVW 3918 Query: 1416 SQLLHTAKSQELSYTVEG--LKPYRIYEFTITLCNSVGCVTSASGAGQTLAAAPAQLRPP 1473 S+ L + EG L+P+ +YE+ + CNS G V S QTL A P P Sbjct: 3919 SE-------GALEFMDEGDTLRPFTLYEYRVRACNSKGSVESLWSLTQTLEAPPQDFPAP 3971 Query: 1474 LVKGINSTTIHLKWFPPEELNGPSPIYQLERRE 1506 + ++ ++ L W PE NG Y++ +E Sbjct: 3972 WAQATSAHSVLLNWTKPESPNGIISHYRVVYQE 4004 Score = 129 bits (325), Expect = 2e-29 Identities = 95/312 (30%), Positives = 142/312 (45%), Gaps = 53/312 (16%) Query: 1204 SATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTE--LHV 1261 S T NL P+ Y++ + A S G S + T + PQ +SPP KI + E + + Sbjct: 3460 SYTDVNLKPYMTYEYRISAWNSYGRGLSKAVRARTKEDVPQGVSPPTWTKIDNLEDTIVL 3519 Query: 1262 EWSPPAELNGIIIRYELY---MRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALK 1318 W P + NG II Y L + R R T + S++ Sbjct: 3520 NWRKPIQSNGPIIYYILLRNGIERFRGTSLSFSDKE------------------------ 3555 Query: 1319 PPQTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSL 1378 G++P+ +Y +++ A +AG +S+ V T + P ++PPS+ LS+ +L Sbjct: 3556 ---------GIQPFQEYSYQLKACTVAGCATSSKVVAATTQGVPESILPPSITALSAVAL 3606 Query: 1379 NISWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYR 1438 ++SW P + G + Y I + + L+HT + +TV GL+PY Sbjct: 3607 HLSWSVPEKS--NGVIKEYQIRQVGKG------------LIHTDTTDRRQHTVTGLQPYT 3652 Query: 1439 IYEFTITLCNSVGCVTSASGAGQTLAAAPAQL-RPPLVKGINSTTIHLKWFPPEELNGPS 1497 Y FT+T C S GC +S GQTL AAP + P INSTT+ L W PE+ NG Sbjct: 3653 NYSFTLTACTSAGCTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVELYWSLPEKPNGLV 3712 Query: 1498 PIYQLERRESSL 1509 YQL R + L Sbjct: 3713 SQYQLSRNGNLL 3724 Score = 123 bits (308), Expect = 2e-27 Identities = 105/395 (26%), Positives = 166/395 (42%), Gaps = 55/395 (13%) Query: 1110 FLDTDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYI-IPIGSDSVTLT 1168 + D +L PY Y Y I N +G S AV +TK VP+G ++ I D++ L Sbjct: 3461 YTDVNLKPYMTYEYRISAWNSYGRGLSKAVRARTKEDVPQGVSPPTWTKIDNLEDTIVLN 3520 Query: 1169 WTTLSNQSGPIEKYILSCAPLAGGQPCVSYEGHETS-ATIWNLVPFAKYDFSVQACTSGG 1227 W +GPI YIL L G + G S + + PF +Y + ++ACT G Sbjct: 3521 WRKPIQSNGPIIYYIL----LRNG--IERFRGTSLSFSDKEGIQPFQEYSYQLKACTVAG 3574 Query: 1228 CLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTK 1287 C S + T Q P+ + PP + +S+ LH+ WS P + NG+I Y++ R++ Sbjct: 3575 CATSSKVVAATTQGVPESILPPSITALSAVALHLSWSVPEKSNGVIKEYQI--RQVGKGL 3632 Query: 1288 ETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGS 1347 T R T+TGL+PYT Y F + A AG Sbjct: 3633 IHTDTTDR--------------------------RQHTVTGLQPYTNYSFTLTACTSAGC 3666 Query: 1348 VSSAWVSERTGESAP--VFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLSEQ 1405 SS +T ++AP V++ P + ++S ++ + W P G V Y ++ Sbjct: 3667 TSSEPFLGQTLQAAPEGVWVTPRHII-INSTTVELYWSLP--EKPNGLVSQYQLS----- 3718 Query: 1406 SPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAA 1465 LL S+E ++T + L+P Y + + + G S QT + Sbjct: 3719 --------RNGNLLFLGGSEEQNFTDKNLEPNSRYTYKLEVKTGGGSSASDDYIVQTPMS 3770 Query: 1466 APAQLRPPL-VKGINSTTIHLKWFPPEELNGPSPI 1499 P ++ PP + I +I + W PP L P+ Sbjct: 3771 TPEEIYPPYNITVIGPYSIFVAWIPPGILIPEIPV 3805 Score = 123 bits (308), Expect = 2e-27 Identities = 120/484 (24%), Positives = 193/484 (39%), Gaps = 61/484 (12%) Query: 1052 KTPFQQP----PPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYS- 1106 KTP P P + S+ I + W PP+ PN + Y + R I + +S Sbjct: 3861 KTPEAAPMDLNSPVLKALGSACIEIKWMPPEKPNGIIINYFIYRRPAGIEEESVLFVWSE 3920 Query: 1107 --IQYFLDTDLL-PYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSD 1163 +++ + D L P+T Y Y + N GS S+ +T P+ + + + Sbjct: 3921 GALEFMDEGDTLRPFTLYEYRVRACNSKGSVESLWSLTQTLEAPPQ-DFPAPWAQATSAH 3979 Query: 1164 SVTLTWTTLSNQSGPIEKYILSCAPLAG----GQPCV---SYEGHETSATIWNLVPFAKY 1216 SV L WT + +G I Y + P V + +G A ++ L PF Y Sbjct: 3980 SVLLNWTKPESPNGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTY 4039 Query: 1217 DFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPKM-QKISSTELHVEWSPPAELNGIIIR 1275 V A G + S + T ++ P L + QK + L ++WS P NG+I Sbjct: 4040 RIGVVAANHAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWSEPMRTNGVIKT 4099 Query: 1276 YELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKY 1335 Y ++ S G+L N L L+P+T Y Sbjct: 4100 YNIF-------------------SDGFLE----YSGLNRQFL--------FRRLDPFTLY 4128 Query: 1336 EFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVV 1395 + A AG SA T E+ P + P+V + S S+ +SW +P + GK++ Sbjct: 4129 TLTLEACTRAGCAHSAPQPLWTDEAPPDSQLAPTVHSVKSTSVELSWSEPVN--PNGKII 4186 Query: 1396 GYDI-------NMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCN 1448 Y++ Q+ Q + F++ + + Y GL+P+ E+ I N Sbjct: 4187 RYEVIRRCFEGKAWGNQTIQADEKIVFTE--YNTERNTFMYNDTGLQPWTQCEYKIYTWN 4244 Query: 1449 SVGCVTSASGAGQTLAAAPAQLRPPLVK--GINSTTIHLKWFPPEELNGPSPIYQLERRE 1506 S G S+ +TL A P L PP++ +N + + W PPE+ NG Y+L+R E Sbjct: 4245 SAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRNE 4304 Query: 1507 SSLP 1510 P Sbjct: 4305 MLYP 4308 Score = 119 bits (297), Expect = 3e-26 Identities = 114/455 (25%), Positives = 182/455 (40%), Gaps = 63/455 (13%) Query: 1059 PPRGQVQSSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPY 1118 PP V A+ ++W PP N L+Y + I T Q T L+P+ Sbjct: 2729 PPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHMPDPHITLTNVTSAVLSQKV--THLIPF 2786 Query: 1119 TKYSYYIETTN-----VHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLS 1173 T YS I + + G T S+ T P VP+ LS +IP+ V ++W S Sbjct: 2787 TNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLS-VIPLSESYVVISWQPPS 2845 Query: 1174 NQSGPIEKYILSCA----PLAGGQPCVSYEGHET-SATIW-----NLVPFAKYDFSVQAC 1223 +GP +Y L PLA P H S T W L F Y++ + Sbjct: 2846 KPNGPNLRYELLRRKIQQPLASNPPEDLNRWHNIYSGTQWLYEDKGLSRFTTYEYMLFVH 2905 Query: 1224 TSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPA--ELNGIIIRYELYMR 1281 S G S +TVTT P+R + ++ T + V W+ P +L G + Y L+ Sbjct: 2906 NSVGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVEYYTLF-- 2963 Query: 1282 RLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITG-LEPYTKYEFRVL 1340 W S S N++ P + + G L+P T+Y + Sbjct: 2964 --------------------WSSATS-----NDSLKILPDVNSHVIGHLKPNTEYWIFIS 2998 Query: 1341 AVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDIN 1400 N S++SA + T + P M+PP V ++S ++ + W P++ G V Y I Sbjct: 2999 VFNGVHSINSAGLHATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSN--PNGVVTEYSIY 3056 Query: 1401 MLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAG 1460 + ++ L T + S+ + L P+ IY+ + +C CV S Sbjct: 3057 VNNK-------------LYKTGMNVPGSFILRDLSPFTIYDIQVEVCTIYACVKSNGTQI 3103 Query: 1461 QTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNG 1495 T+ P+ + P ++GI S ++ + W P + NG Sbjct: 3104 TTVEDTPSDIPTPTIRGITSRSLQIDWVSPRKPNG 3138 Score = 114 bits (286), Expect = 6e-25 Identities = 117/462 (25%), Positives = 177/462 (38%), Gaps = 59/462 (12%) Query: 1058 PPPRGQVQSSSAINLSWSPPDS--PNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDT-- 1113 PP V +I ++W PP P LL DG + +S+ + T Sbjct: 3777 PPYNITVIGPYSIFVAWIPPGILIPEIPVEYNVLLNDG-----SVTPLAFSVGHHQSTLL 3831 Query: 1114 -DLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTL 1172 +L P+T+Y I+ S + KT P +L + +GS + + W Sbjct: 3832 ENLTPFTQYEIRIQACQNGSCGVSSRMFVKTPEAAPM-DLNSPVLKALGSACIEIKWMPP 3890 Query: 1173 SNQSGPIEKYILSCAPLAGGQPCVSYEGHETSATIWN----LVPFAKYDFSVQACTSGGC 1228 +G I Y + P + V + E + + L PF Y++ V+AC S G Sbjct: 3891 EKPNGIIINYFIYRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLYEYRVRACNSKGS 3950 Query: 1229 LHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYEL-YMRRLRSTK 1287 + SL T +APPQ P Q S+ + + W+ P NGII Y + Y R Sbjct: 3951 VESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPESPNGIISHYRVVYQER----- 4005 Query: 1288 ETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGS 1347 + F S + H+F +K + GLEP+T Y V+A N AG Sbjct: 4006 ----PDDPTFNSP---TVHAFT-------VKGTSHQAHLYGLEPFTTYRIGVVAANHAGE 4051 Query: 1348 VSSAWVSERTGESAPV----FMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLS 1403 + S W +T ES+P F++ + +L + W +P T G + Y+I Sbjct: 4052 ILSPWTLIQTLESSPSGLRNFIVEQKE---NGRALLLQWSEPMR--TNGVIKTYNI---- 4102 Query: 1404 EQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTL 1463 FS + L P+ +Y T+ C GC SA T Sbjct: 4103 -----------FSDGFLEYSGLNRQFLFRRLDPFTLYTLTLEACTRAGCAHSAPQPLWTD 4151 Query: 1464 AAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQLERR 1505 A P P V + ST++ L W P NG Y++ RR Sbjct: 4152 EAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRR 4193 Score = 113 bits (283), Expect = 1e-24 Identities = 113/498 (22%), Positives = 193/498 (38%), Gaps = 74/498 (14%) Query: 1027 VTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLT 1086 +T C S+ L+++ + P + PP + SS + LSW+PP N Sbjct: 2032 LTACTLAGCTESSHALNISTP---QEAPQEVQPPVAKSLPSSLL-LSWNPPKKANGIITQ 2087 Query: 1087 YSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPG 1146 Y L DG IY+ ++ Y++ TDL +T + + + G T S V T Sbjct: 2088 YCLYMDGRLIYSGSEEN-YTV-----TDLAVFTPHQFLLSACTHVGCTNSSWVLLYTAQL 2141 Query: 1147 VPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEGHETSAT 1206 PE ++ + + S ++ + W SG +E+Y+L + H T Sbjct: 2142 PPE-HVDSPVLTVLDSRTIHIQWKQPRKISGILERYVLYMS------------NHTHDFT 2188 Query: 1207 IWNLV----------------PFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRLSPPK 1250 IW+++ P KY + ACT GGC S T + P+ + PK Sbjct: 2189 IWSVIYNSTELFQDHMLQYVLPGNKYLIKLGACTGGGCTVSEASEALTDEDIPEGVPAPK 2248 Query: 1251 MQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVE 1310 S +V W+ P NG+I Y LY+ + + +S LS ++ Sbjct: 2249 AHSYSPDSFNVSWTEPEYPNGVITSYGLYL------------DGILIHNSSELSYRAY-- 2294 Query: 1311 SANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSV 1370 G P++ + FRV A G V RT E+ P + V Sbjct: 2295 -----------------GFAPWSLHSFRVQACTAKGCALGPLVENRTLEAPPEGTVNVFV 2337 Query: 1371 FPLSSYSLNISWEKP--ADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELS 1428 S ++ WE P + + V+ I + ++ + ++++++ + L Sbjct: 2338 KTQGSRKAHVRWEAPFRPNGLLTHSVLFTGIFYVDPVGNNYTL-LNVTKVMYSGEETNLW 2396 Query: 1429 YTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWF 1488 ++GL P+ Y + + NS G + + AP + PP + T++ + W Sbjct: 2397 VLIDGLVPFTNYTVQVNISNSQGSLITDPITIAMPPGAPDGVLPPRLSSATPTSLQVVWS 2456 Query: 1489 PPEELNGP-SPIYQLERR 1505 P N P SP YQL+ R Sbjct: 2457 TPARNNAPGSPRYQLQMR 2474 Score = 113 bits (283), Expect = 1e-24 Identities = 116/467 (24%), Positives = 178/467 (38%), Gaps = 50/467 (10%) Query: 1054 PFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLTYSL-LRDGFE-----IYTTEDQYPYSI 1107 P PP+ Q + I ++W PP N + Y+L +R+ FE I+ + + Sbjct: 4532 PSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNSFGM 4591 Query: 1108 QYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGV-----PEGNLTLSYIIPIGS 1162 Q ++ L P+ +Y I+ G S T+ P + P +L + Sbjct: 4592 QSYIVNQLKPFHRYEIRIQACTTLGCASS-DWTFIQTPEIAPLMQPPPHLEVQMAPGGFQ 4650 Query: 1163 DSVTLTWTTLSNQSGPIEKYILSCAPLAG----GQPCVSYEGHETSATIWNLVPFAKYDF 1218 +V+L WT +G + Y L +A P + Y G TS L+PF +Y++ Sbjct: 4651 PTVSLLWTGPLQPNGKVLYYELYRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEY 4710 Query: 1219 SVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYEL 1278 V A S G S T APP+ L P ISST+ V S P + NGI+ Y L Sbjct: 4711 QVWAVNSAGKAPSSWTWCRTGPAPPEGLRAPTFHVISSTQAVVNISAPGKPNGIVSLYRL 4770 Query: 1279 YMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFR 1338 + + SE T T+ GL+ +T Y Sbjct: 4771 FSSSAHGAETVLSEGM--------------------------ATQQTLHGLQAFTNYSIG 4804 Query: 1339 VLAVNMAGSVSSAWVSE-RTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVVGY 1397 V A S +E RT + P + P + L+S + + W P G + Y Sbjct: 4805 VEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPM--FPNGVIHSY 4862 Query: 1398 DINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTS 1455 ++ P ++P SQ+ +T Q+ S + GL+PY Y+ + N VG S Sbjct: 4863 ELQFHVACPPDSALPCTPSQIETKYTGLGQKAS--LGGLQPYTTYKLRVVAHNEVGSTAS 4920 Query: 1456 ASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQL 1502 + T P Q R P N + + + W LNG Y L Sbjct: 4921 EWISFTTQKELP-QYRAPFSVDSNLSVVCVNWSDTFLLNGQLKEYVL 4966 Score = 107 bits (268), Expect = 7e-23 Identities = 106/419 (25%), Positives = 168/419 (40%), Gaps = 54/419 (12%) Query: 1092 DGFEIYTTEDQYPYSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGN 1151 D +Y ++Q Y + L P+T+Y Y + ++ GS S +T P+ Sbjct: 1904 DSILVYQGKEQSVY------EGGLQPFTEYLYRVIASHEGGSVYSDWSRGRTTGAAPQSV 1957 Query: 1152 LTLSYIIPIGSDSVTLTWTTLSNQSGPIEKYILSC----APLAGGQPCVSYEGHETS--- 1204 T S + + S+ +TW G IEKYIL + P S E TS Sbjct: 1958 PTPSRVRSLNGYSIEVTWDE-PVVRGVIEKYILKAYSEDSTRPPRMPSASAEFVNTSNLT 2016 Query: 1205 ATIWNLVPFAKYDFSVQACTSGGCLHSL-PITVTTAQAPPQRLSPPKMQKISSTELHVEW 1263 + L+PF Y ++ ACT GC S + ++T Q PQ + PP + + S+ L + W Sbjct: 2017 GILTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPPVAKSLPSS-LLLSW 2075 Query: 1264 SPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTM 1323 +PP + NGII +Y LYM + R+ S + EN Sbjct: 2076 NPPKKANGIITQYCLYM------------DGRLIYS-----------GSEEN-------- 2104 Query: 1324 TTITGLEPYTKYEFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWE 1383 T+T L +T ++F + A G +S+WV T + P + P + L S +++I W+ Sbjct: 2105 YTVTDLAVFTPHQFLLSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWK 2164 Query: 1384 KPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFT 1443 +P G + Y + M S + +I + L Y + G K Y Sbjct: 2165 QP--RKISGILERYVLYM-SNHTHDFTIWSVIYNSTELFQDHMLQYVLPGNK----YLIK 2217 Query: 1444 ITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNGPSPIYQL 1502 + C GC S + T P + P + + ++ W PE NG Y L Sbjct: 2218 LGACTGGGCTVSEASEALTDEDIPEGVPAPKAHSYSPDSFNVSWTEPEYPNGVITSYGL 2276 Score = 88.2 bits (217), Expect = 6e-17 Identities = 77/307 (25%), Positives = 137/307 (44%), Gaps = 39/307 (12%) Query: 1191 GGQPCVSYEGHETSATIWNLVPFAKYDFSVQACTSGGCLHSLPITVTTAQAPPQRL-SPP 1249 G + Y+G E S L PF +Y + V A GG ++S T A PQ + +P Sbjct: 1902 GNDSILVYQGKEQSVYEGGLQPFTEYLYRVIASHEGGSVYSDWSRGRTTGAAPQSVPTPS 1961 Query: 1250 KMQKISSTELHVEWSPPAELNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFV 1309 +++ ++ + V W P + G+I +Y L ++ E ++ R+ +S FV Sbjct: 1962 RVRSLNGYSIEVTWDEPV-VRGVIEKYIL-----KAYSEDSTRPPRMPSASA-----EFV 2010 Query: 1310 ESANENALKPPQTMTTITGLEPYTKYEFRVLAVNMAGSVSSAW-VSERTGESAPVFMIPP 1368 ++N + +TGL P+ Y + A +AG S+ ++ T + AP + PP Sbjct: 2011 NTSNLTGI--------LTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPP 2062 Query: 1369 SVFPLSSYSLNISWEKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQLLHTAKSQELS 1428 L S SL +SW P G + Y + M +L+++ + + Sbjct: 2063 VAKSLPS-SLLLSWNPPKK--ANGIITQYCLYM-------------DGRLIYSGSEE--N 2104 Query: 1429 YTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVKGINSTTIHLKWF 1488 YTV L + ++F ++ C VGC S+ T P + P++ ++S TIH++W Sbjct: 2105 YTVTDLAVFTPHQFLLSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWK 2164 Query: 1489 PPEELNG 1495 P +++G Sbjct: 2165 QPRKISG 2171 Score = 75.1 bits (183), Expect = 5e-13 Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 17/170 (10%) Query: 1115 LLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSN 1174 L P T+Y +I N S S + T G P+G L +I I S +V + WT+ SN Sbjct: 2987 LKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVI-INSTAVRVIWTSPSN 3045 Query: 1175 QSGPIEKYILSCAPLAGGQPCVSYEGHET------SATIWNLVPFAKYDFSVQACTSGGC 1228 +G + +Y + V+ + ++T S + +L PF YD V+ CT C Sbjct: 3046 PNGVVTEYSIY----------VNNKLYKTGMNVPGSFILRDLSPFTIYDIQVEVCTIYAC 3095 Query: 1229 LHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWSPPAELNGIIIRYEL 1278 + S +TT + P + P ++ I+S L ++W P + NGII+ Y+L Sbjct: 3096 VKSNGTQITTVEDTPSDIPTPTIRGITSRSLQIDWVSPRKPNGIILGYDL 3145 Score = 49.3 bits (116), Expect = 3e-05 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Query: 1417 QLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQTLAAAPAQLRPPLVK 1476 + +HT SYT LKPY YE+ I+ NS G S + +T P + PP Sbjct: 3449 ETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGLSKAVRARTKEDVPQGVSPPTWT 3508 Query: 1477 GINS--TTIHLKWFPPEELNGPSPIYQLER 1504 I++ TI L W P + NGP Y L R Sbjct: 3509 KIDNLEDTIVLNWRKPIQSNGPIIYYILLR 3538 >gi|21264602 laminin alpha 5 [Homo sapiens] Length = 3695 Score = 394 bits (1011), Expect = e-109 Identities = 247/756 (32%), Positives = 351/756 (46%), Gaps = 85/756 (11%) Query: 338 EAHPLSFVNDNDVGTS--WVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFF-SPQ 393 +AHP S D GT W S + + N+ ++V L+ GQ + V Y++I+F SP+ Sbjct: 113 KAHPASNAID---GTERWWQSPPLSRGLEYNE---VNVTLDLGQVFHVAYVLIKFANSPR 166 Query: 394 PTEIRIQRKKENSLDWEDWQYFA---RNC-GAFGMKNNGDLEKPDSVNCL-QLSNFTPYS 448 P ++R + ++ WQ+FA R+C FG + + + D+ C + S P Sbjct: 167 PDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLE 226 Query: 449 RGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAV 500 G + S++ N RPG NF +P L+EF KAT +R F H Sbjct: 227 NGEIVVSLV----NGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT 282 Query: 501 NLRHRYYAVDEITISGRCQCHGHADNCDTT--SQPYRCLCSQESFTEGLHCDRCLPLYND 558 R YY++ +I+I GRC CHGHAD CD + P+R C+ + T G CDRC P +N Sbjct: 283 VTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQ 342 Query: 559 KPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVD----PFPFEHFRGGGGVCDDCEHNTTG 614 +P++ A C+ C C H+ C+Y+ VD + GGGVC DC+H+TTG Sbjct: 343 QPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTG 402 Query: 615 RNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN 674 NCE C F+R + VC+ C+C++ T C+ + G+C C+ + SG +C+ Sbjct: 403 VNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDG---TCEDLTGRCYCRPNFSGERCD 459 Query: 675 QCQNGFYNLQELDPDGCSP---------------CNCNTSGTVDGDITCHQNSGQCKCKA 719 C GF P S C+C+ +GT G+C CK Sbjct: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519 Query: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779 N G C+ C G F GC+PCQC+ G + C+P +GQC C+ +G CD Sbjct: 520 NFQGTHCELCAPG------FYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR 573 Query: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839 C ++ + C+ C C AG+LP C+ + G+C+C+P G C++C G Sbjct: 574 CAPGYFHFPL--CQLCGCSPAGTLP-EGCD-EAGRCLCQPEFAGPHCDRCRPGYHGFPN- 628 Query: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899 C C CD G ++ LC + G C C+ G TG C +C P F C Sbjct: 629 ----CQACTCDPRGALD--QLCG-AGGLCRCRPGYTGTACQECSP-----GFHGFPSCVP 676 Query: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTG-- 957 C C + G+L CDP SGQC C P G RC+ C PG Y N C SCH G Sbjct: 677 CHCSAEGSLHAA-CDPRSGQCSCRPRVTGLRCDTCVPGAY----NFPYCEAGSCHPAGLA 731 Query: 958 AVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSGALN--ETC 1014 V+ C+C+ A + G CD+CK ++G P C C+C L G L C Sbjct: 732 PVDPALPEAQVPCMCR-AHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAEC 790 Query: 1015 HLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 TGQCFCK V G C +C LD + GC Sbjct: 791 QPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGC 826 Score = 212 bits (540), Expect = 2e-54 Identities = 136/454 (29%), Positives = 196/454 (43%), Gaps = 55/454 (12%) Query: 489 FHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN-CDTTSQPYRCLCSQESFTEGL 547 F Y T ++ + R + +I ++ C G N C + RCLC +G Sbjct: 468 FPSCYPTPSSSNDTREQVLPAGQI-VNCDCSAAGTQGNACRKDPRVGRCLCKPNF--QGT 524 Query: 548 HCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDD 607 HC+ C P + Y C+PCQC+S + + DP G C Sbjct: 525 HCELCAPGF-----------YGPGCQPCQCSSPGVA---DDRCDP--------DTGQCR- 561 Query: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667 C G C+ C +F +C+ C C GT CD+ G+C C+ Sbjct: 562 CRVGFEGATCDRCAPGYFH--------FPLCQLCGCSPAGTLPEG--CDE-AGRCLCQPE 610 Query: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727 +G C++C+ G++ C C C+ G +D C G C+C+ G C Sbjct: 611 FAGPHCDRCRPGYHGFPN-----CQACTCDPRGALDQ--LCGAG-GLCRCRPGYTGTACQ 662 Query: 728 HCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL 787 C+ GF S C PC C+ GS++ C+P SGQC C+ GL+CDTC Y Sbjct: 663 ECSPGFHGFPS-----CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF 717 Query: 788 DVTNCKACDCDTAGSLPGTVCNAKTG-QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLP 846 C+A C AG P + C+C+ +VEG C++C G + L +N C Sbjct: 718 PY--CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTR 775 Query: 847 CNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906 C+CD GT+ G C TGQC CK V G C C+ + L ++ C+ C CD G Sbjct: 776 CSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGG 835 Query: 907 TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940 L G C+P +G C C PN QG C++ Y+ Sbjct: 836 AL-GQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868 Score = 187 bits (474), Expect = 9e-47 Identities = 121/377 (32%), Positives = 173/377 (45%), Gaps = 50/377 (13%) Query: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595 CLC G C C P + +R ++ C PCQC+ HS C Sbjct: 1831 CLCPASY--RGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRC----------- 1873 Query: 596 EHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILC 655 G GVC DC+HNT G +CE C+ F DPSA V PC +V + N + C Sbjct: 1874 ---LPGSGVCVDCQHNTEGAHCERCQAGFVSS-RDDPSAPCVSCPCPL-SVPSNNFAEGC 1928 Query: 656 DQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDI---TCHQ 710 GG QC CK +G C +C GF+ + C PC+C SG D ++ C Sbjct: 1929 VLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDC--SGNGDPNLLFSDCDP 1986 Query: 711 NSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK 769 +G C+ C + G RC+ C GF + + C C C G+ + C+PHSG C CK Sbjct: 1987 LTGACRGCLRHTTGPRCEICAPGF-YGNALLPGNCTRCDCTPCGT--EACDPHSGHCLCK 2043 Query: 770 KEAKGLQCDTCRENFYGLD-VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828 G +CD C+E +G D C+ C C A G+ C+ ++GQC C+P G QC + Sbjct: 2044 AGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAE--GSECHPQSGQCHCRPGTMGPQCRE 2101 Query: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQC-EPHRY 887 C G + L + C C C C+ TG+C C G++G RC+ C + H+ Sbjct: 2102 CAPGYWGLPEQG---CRRCQCP-------GGRCDPHTGRCNCPPGLSGERCDTCSQQHQV 2151 Query: 888 NL---TIDNFQHCQMCE 901 + + + HC++C+ Sbjct: 2152 PVPGGPVGHSIHCEVCD 2168 Score = 174 bits (440), Expect = 8e-43 Identities = 111/324 (34%), Positives = 143/324 (44%), Gaps = 54/324 (16%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 CQCHGH+D C S C+ Q + TEG HC+RC F + C C C Sbjct: 1864 CQCHGHSDRCLPGSGV--CVDCQHN-TEGAHCERC-----QAGFVSSRDDPSAPCVSCPC 1915 Query: 578 ------NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631 N+ ++ C RGG C C+ G +CE C FF + Sbjct: 1916 PLSVPSNNFAEGCV------------LRGGRTQCL-CKPGYAGASCERCAPGFF----GN 1958 Query: 632 PSAI-DVCKPCDCDTVGTRNGSIL-CDQIGGQCN-CKRHVSGRQCNQCQNGFYNLQELDP 688 P + C+PCDC G N CD + G C C RH +G +C C GFY L P Sbjct: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYG-NALLP 2017 Query: 689 DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCE 745 C+ C+C GT C +SG C CKA V G RCD C +FGF GC Sbjct: 2018 GNCTRCDCTPCGTE----ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCG-----GCR 2068 Query: 746 PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPG 805 PC C ++ C+P SGQC C+ G QC C ++GL C+ C C PG Sbjct: 2069 PCACGPAAEGSE-CHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC------PG 2121 Query: 806 TVCNAKTGQCICKPNVEGRQCNKC 829 C+ TG+C C P + G +C+ C Sbjct: 2122 GRCDPHTGRCNCPPGLSGERCDTC 2145 Score = 167 bits (422), Expect = 9e-41 Identities = 113/344 (32%), Positives = 151/344 (43%), Gaps = 41/344 (11%) Query: 662 CNCKRHVSGRQCNQCQNGFY-NLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKA 719 C C G C +C GFY +++ L C PC C+ G D C SG C C+ Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCH--GHSD---RCLPGSGVCVDCQH 1885 Query: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKF---CNPHSG--QCECKKEAKG 774 N G C+ C GF R C C C L N F C G QC CK G Sbjct: 1886 NTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAG 1945 Query: 775 LQCDTCRENFYGLDV---TNCKACDCDTAG--SLPGTVCNAKTGQCI-CKPNVEGRQCNK 828 C+ C F+G + ++C+ CDC G +L + C+ TG C C + G +C Sbjct: 1946 ASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005 Query: 829 CLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPH 885 C G FY N+ L C C+C GT C+ +G C CK GVTG RC++C+ Sbjct: 2006 CAPG-FY---GNALLPGNCTRCDCTPCGTE----ACDPHSGHCLCKAGVTGRRCDRCQEG 2057 Query: 886 RYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNA 945 + D C+ C C G+ C P SGQC C P G +C +C PG++ P Sbjct: 2058 HFGF--DGCGGCRPCACGPAAE--GSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ- 2112 Query: 946 TGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHY 989 GC C C C+ TG+C C ++G+RCD C + Sbjct: 2113 -GCRRCQCP-----GGRCDPHTGRCNCPPG-LSGERCDTCSQQH 2149 Score = 165 bits (417), Expect = 4e-40 Identities = 114/340 (33%), Positives = 150/340 (44%), Gaps = 44/340 (12%) Query: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVG------CEPCQCNLHGSVNKFCNPHSGQC-E 767 C C A+ G C C GF + DV C PCQC HG ++ C P SG C + Sbjct: 1831 CLCPASYRGDSCQECAPGF-----YRDVKGLFLGRCVPCQC--HGHSDR-CLPGSGVCVD 1882 Query: 768 CKKEAKGLQCDTCRENFYGL---DVTNCKACDCDTA----GSLPGTVCNAKTGQCICKPN 820 C+ +G C+ C+ F C +C C + G V QC+CKP Sbjct: 1883 CQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPG 1942 Query: 821 VEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQCP-CKLGVTG 876 G C +C G F C PC+C G N LL C+ TG C C TG Sbjct: 1943 YAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPN--LLFSDCDPLTGACRGCLRHTTG 2000 Query: 877 LRCNQCEPHRY-NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQ 935 RC C P Y N + +C C+C GT CDP SG CLC GRRC++CQ Sbjct: 2001 PRCEICAPGFYGNALLPG--NCTRCDCTPCGT---EACDPHSGHCLCKAGVTGRRCDRCQ 2055 Query: 936 PGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQ 995 G + G GC PC+C A C+ +GQC C+ ++ G +C +C Y+G P+ Sbjct: 2056 EGHFGFDG-CGGCRPCAC-GPAAEGSECHPQSGQCHCRPGTM-GPQCRECAPGYWGL-PE 2111 Query: 996 TGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035 G C+ C C C TG+C C ++G +CD C Sbjct: 2112 QG-CRRCQCP-----GGRCDPHTGRCNCPPGLSGERCDTC 2145 Score = 159 bits (401), Expect = 3e-38 Identities = 99/289 (34%), Positives = 135/289 (46%), Gaps = 32/289 (11%) Query: 766 CECKKEAKGLQCDTCRENFY----GLDVTNCKACDCDTAGS--LPGTVCNAKTGQCI-CK 818 C C +G C C FY GL + C C C LPG+ G C+ C+ Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGS------GVCVDCQ 1884 Query: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN----GSLLCNKSTGQCPCKLGV 874 N EG C +C G R + S C+ C C + N G +L T QC CK G Sbjct: 1885 HNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRT-QCLCKPGY 1943 Query: 875 TGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG--TLPGTICDPISGQCL-CVPNRQGRRC 931 G C +C P + + CQ C+C G L + CDP++G C C+ + G RC Sbjct: 1944 AGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC 2003 Query: 932 NQCQPGFY---ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDH 988 C PGFY + PGN T C C T C+ +G C+C+ A + G+RCD+C++ Sbjct: 2004 EICAPGFYGNALLPGNCTRCDCTPCGTEA-----CDPHSGHCLCK-AGVTGRRCDRCQEG 2057 Query: 989 YFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVP 1037 +FGFD G C+PC C + +E CH +GQC C+ G +C C P Sbjct: 2058 HFGFDG-CGGCRPCACGPAAEGSE-CHPQSGQCHCRPGTMGPQCRECAP 2104 Score = 149 bits (377), Expect = 2e-35 Identities = 82/217 (37%), Positives = 106/217 (48%), Gaps = 28/217 (12%) Query: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698 +PC C VG + C+ GGQC C HV GR C++C G++ C PC+C Sbjct: 1436 RPCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWGFPN-----CRPCDC-- 1486 Query: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN---FGFKFLRSFNDVGCEPCQCNLHGS- 754 G C + +GQC C I C C FG L VGCE C C+ G Sbjct: 1487 -----GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPL-----VGCEECNCSGPGIQ 1536 Query: 755 --VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKT 812 + C+ SGQC+C+ G +CDTC F+G C+ CDC AG+ PG VC+ T Sbjct: 1537 ELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP--RCRPCDCHEAGTAPG-VCDPLT 1593 Query: 813 GQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849 GQC CK NV+G +C++C G F L N C C C Sbjct: 1594 GQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630 Score = 147 bits (372), Expect = 6e-35 Identities = 80/233 (34%), Positives = 102/233 (43%), Gaps = 30/233 (12%) Query: 729 CNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLD 788 C L F + G PC C+ G+ C P GQC C G C C ++G Sbjct: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF- 1478 Query: 789 VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLP-- 846 NC+ CDC +C+ TGQCIC P C C Q +F C P Sbjct: 1479 -PNCRPCDCG------ARLCDELTGQCICPPRTIPPDCLLC--------QPQTFGCHPLV 1523 Query: 847 ----CNCDKTGTIN-GSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCE 901 CNC G C+ +GQC C+ VTG RC+ C P + C+ C+ Sbjct: 1524 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSP-----GFHGYPRCRPCD 1578 Query: 902 CDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSC 953 C GT PG +CDP++GQC C N QG +C+QC G F + N GC C C Sbjct: 1579 CHEAGTAPG-VCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630 Score = 137 bits (344), Expect = 1e-31 Identities = 77/231 (33%), Positives = 107/231 (46%), Gaps = 24/231 (10%) Query: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKF 735 C+N +L +G PC C+ G TC GQC C A+VIG C C G+ Sbjct: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGP--TCEPFGGQCPCHAHVIGRDCSRCATGY-- 1475 Query: 736 LRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCKA 794 + C PC C + C+ +GQC C C C+ +G + C+ Sbjct: 1476 ---WGFPNCRPCDCGA-----RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEE 1527 Query: 795 CDCDTAG--SLPGTVCNAKTGQCICKPNVEGRQCNKCLEG-NFYLRQNNSFLCLPCNCDK 851 C+C G L C+ +GQC C+PNV GR+C+ C G + Y R C PC+C + Sbjct: 1528 CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR------CRPCDCHE 1581 Query: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902 GT G +C+ TGQC CK V G +C+QC ++L N + C C C Sbjct: 1582 AGTAPG--VCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630 Score = 136 bits (342), Expect = 2e-31 Identities = 72/211 (34%), Positives = 104/211 (49%), Gaps = 24/211 (11%) Query: 846 PCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSL 905 PC C + G + C GQCPC V G C++C + F +C+ C+C + Sbjct: 1437 PCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWG-----FPNCRPCDCGA- 1488 Query: 906 GTLPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTTGA---VNH 961 +CD ++GQC+C P C CQP F P GC C+C G + Sbjct: 1489 -----RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHP--LVGCEECNCSGPGIQELTDP 1541 Query: 962 ICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQC 1021 C++ +GQC C+ ++ G+RCD C + G+ RC+PC+CH +G C +TGQC Sbjct: 1542 TCDTDSGQCKCRP-NVTGRRCDTCSPGFHGYP----RCRPCDCHEAGTAPGVCDPLTGQC 1596 Query: 1022 FCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052 +CK+ V G KCD C LD N GC++ Sbjct: 1597 YCKENVQGPKCDQCSLGTFSLDAANPKGCTR 1627 Score = 135 bits (341), Expect = 2e-31 Identities = 81/259 (31%), Positives = 108/259 (41%), Gaps = 36/259 (13%) Query: 524 ADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKS 583 A+ C +CLC G C+RC P + P G +C+PC C+ + Sbjct: 1925 AEGCVLRGGRTQCLCKPGY--AGASCERCAPGFFGNPLVLGS-----SCQPCDCSGNGDP 1977 Query: 584 CHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDC 643 DP G C C +TTG CE+C F+ + C CDC Sbjct: 1978 NLLFSDCDPLT--------GACRGCLRHTTGPRCEICAPGFYGNALLPGN----CTRCDC 2025 Query: 644 DTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVD 703 GT CD G C CK V+GR+C++CQ G + GC PC C G Sbjct: 2026 TPCGTE----ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCG--GCRPCAC---GPAA 2076 Query: 704 GDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHS 763 CH SGQC C+ +G +C C G+ L + GC CQC C+PH+ Sbjct: 2077 EGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP---EQGCRRCQCP-----GGRCDPHT 2128 Query: 764 GQCECKKEAKGLQCDTCRE 782 G+C C G +CDTC + Sbjct: 2129 GRCNCPPGLSGERCDTCSQ 2147 Score = 130 bits (327), Expect = 1e-29 Identities = 76/229 (33%), Positives = 103/229 (44%), Gaps = 35/229 (15%) Query: 568 YAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627 Y +PC C+ + + +PF GG C C + GR+C C ++ Sbjct: 1431 YNNGARPCGCHEVGAT---GPTCEPF--------GGQCP-CHAHVIGRDCSRCATGYW-- 1476 Query: 628 VGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELD 687 C+PCDC G+ LCD++ GQC C C CQ + L Sbjct: 1477 ------GFPNCRPCDC-------GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLV 1523 Query: 688 PDGCSPCNCNTSGTVD-GDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEP 746 GC CNC+ G + D TC +SGQCKC+ NV G RCD C+ GF C P Sbjct: 1524 --GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRP 1576 Query: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795 C C+ G+ C+P +GQC CK+ +G +CD C + LD N K C Sbjct: 1577 CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGC 1625 Score = 123 bits (309), Expect = 1e-27 Identities = 89/329 (27%), Positives = 129/329 (39%), Gaps = 62/329 (18%) Query: 747 CQCNLHGSV---NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSL 803 C C+ H +P QC C+ G CD C F + K ++A Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGF---NQQPWKPATANSANEC 356 Query: 804 PGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK 863 C C P V+ R+ ++ L+G T G +C Sbjct: 357 QSCNCYGHATDCYYDPEVDRRRASQSLDG---------------------TYQGGGVC-- 393 Query: 864 STGQCPCKLGVTGLRCNQCEPHRY---NLTIDNFQHCQMCECDSLGTLPGTICDPISGQC 920 C+ TG+ C +C P Y N +D+ C+ C C+S T GT C+ ++G+C Sbjct: 394 ----IDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFT-DGT-CEDLTGRC 447 Query: 921 LCVPNRQGRRCNQCQPGF------YISPGNATGC----LP------CSCHTTGAVNHICN 964 C PN G RC+ C GF Y +P ++ LP C C G + C Sbjct: 448 YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACR 507 Query: 965 S--LTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCF 1022 G+C+C+ + G C+ C ++G CQPC C G ++ C TGQC Sbjct: 508 KDPRVGRCLCKP-NFQGTHCELCAPGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCR 561 Query: 1023 CKQFVTGSKCDACVPSASHLDVNNLLGCS 1051 C+ G+ CD C P H + L GCS Sbjct: 562 CRVGFEGATCDRCAPGYFHFPLCQLCGCS 590 Score = 83.2 bits (204), Expect = 2e-15 Identities = 59/218 (27%), Positives = 79/218 (36%), Gaps = 64/218 (29%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 C CH T +P+ C + G C RC Y P NC+PC C Sbjct: 1438 CGCH-EVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDC 1486 Query: 578 NSH--------------------------SKSCHYNISVDPFPFEHFRGGGGV------- 604 + + CH + + E G G+ Sbjct: 1487 GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCE----ECNCSGPGIQELTDPT 1542 Query: 605 CDD------CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQI 658 CD C N TGR C+ C F C+PCDC GT G +CD + Sbjct: 1543 CDTDSGQCKCRPNVTGRRCDTCSPGFH--------GYPRCRPCDCHEAGTAPG--VCDPL 1592 Query: 659 GGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC 696 GQC CK +V G +C+QC G ++L +P GC+ C C Sbjct: 1593 TGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630 Score = 68.6 bits (166), Expect = 5e-11 Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 28/132 (21%) Query: 937 GFYISPGNAT----------------GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980 G++ISP +++ G PC CH GA C GQC C A + G+ Sbjct: 1408 GYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCH-AHVIGR 1466 Query: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSAS 1040 C +C Y+GF C+PC+C GA C +TGQC C C C P Sbjct: 1467 DCSRCATGYWGFP----NCRPCDC---GA--RLCDELTGQCICPPRTIPPDCLLCQPQT- 1516 Query: 1041 HLDVNNLLGCSK 1052 + L+GC + Sbjct: 1517 -FGCHPLVGCEE 1527 >gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] Length = 3333 Score = 325 bits (833), Expect = 2e-88 Identities = 201/637 (31%), Positives = 297/637 (46%), Gaps = 61/637 (9%) Query: 338 EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFF-SPQPT 395 +AHP++ D W S ++ TQ N+ +++ L+ GQ + V YI+I+F SP+P Sbjct: 112 KAHPVTNAIDGSERW-WQSPPLSSGTQYNR---VNLTLDLGQLFHVAYILIKFANSPRPD 167 Query: 396 EIRIQRKKENSLDWEDWQYFARN----CGAFGMKNNGDLEKPDSVNCL-QLSNFTPYSRG 450 ++R + + WQYFA + FG + N + + D V C+ + S P G Sbjct: 168 LWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENG 227 Query: 451 NVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNL 502 V S++ N RPG NF + +L+EF KAT IR F H Sbjct: 228 EVVVSLI----NGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283 Query: 503 RHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562 R YY++ +I+I G+C C+GHA+ C+ + C + T G CDRC YN + +R Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343 Query: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVD----PFPFEHFRGGGGVCDDCEHNTTGRNCE 618 + C+ C C+ H+ +C+Y+ V+ + GGGVC +C+HNT G NCE Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403 Query: 619 LCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQN 678 C ++R G A D C PC CD C+Q G+C+CK + G C +C Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAI 459 Query: 679 GFYNL--------------QELDP--DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVI 722 G+YN DP C+CN G + H G+C C+ V Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH---GRCLCRPGVE 516 Query: 723 GLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRE 782 G RCD C GF ++ C+ C C+ GS C+ +GQCEC+ G +CD C Sbjct: 517 GPRCDTCRSGF-----YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLS 571 Query: 783 NFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF 842 Y + CD AG++ N+ G C CK +VEG C++C + L + N Sbjct: 572 GAYDFPHCQGSSSACDPAGTI-----NSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPS 626 Query: 843 LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902 C C C K GT++G+ C + G C CK V G C+ CE + L N+ CQ C+C Sbjct: 627 GCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC 686 Query: 903 DSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY 939 D G L ++C SG C C + G+ C + + +Y Sbjct: 687 DIGGAL-SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722 Score = 160 bits (404), Expect = 1e-38 Identities = 85/239 (35%), Positives = 113/239 (47%), Gaps = 21/239 (8%) Query: 729 CNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLD 788 C + L +F G PC+C+ G+ C+P GQC C+ G QC C YG Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGF- 1306 Query: 789 VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCN 848 CK C C +C TGQC C P QC C +F C CN Sbjct: 1307 -PRCKPCSCGR------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAG--CEGCN 1357 Query: 849 CDKTGTINGSL-LCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT 907 C + GTI ++ C++ +GQC CK +TG +C++C Y F C C C+ GT Sbjct: 1358 CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY-----RFPECVPCNCNRDGT 1412 Query: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTTGAVNHICNS 965 PG +CDP +G CLC N +G CN C+ G F++ P N GC C C VN+ C+S Sbjct: 1413 EPG-VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCF---GVNNQCHS 1467 Score = 159 bits (403), Expect = 2e-38 Identities = 120/421 (28%), Positives = 176/421 (41%), Gaps = 76/421 (18%) Query: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739 +Y+++++ G C CN V +I + +C+C+ + G CD C G+ R Sbjct: 287 YYSIKDISIGG--QCVCNGHAEVC-NINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343 Query: 740 -----NDVGCEPCQCNLHGSVNKFCNPH----------------SGQC-ECKKEAKGLQC 777 CE C C+ H S N + +P G C C+ G+ C Sbjct: 344 PAAWEQSHECEACNCHGHAS-NCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNC 402 Query: 778 DTCRENFY---GLDVT---NCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831 + C + +Y G+ V C C CD + C +G+C CKPN G C KC Sbjct: 403 EQCAKGYYRPYGVPVDAPDGCIPCSCDPEHA---DGCEQGSGRCHCKPNFHGDNCEKCAI 459 Query: 832 GN----FYLRQNNSFLCLP------------CNCDKTGTINGSLLCNKSTGQCPCKLGVT 875 G F LR + P C+C+ G + +C+ + G+C C+ GV Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPE--ICD-AHGRCLCRPGVE 516 Query: 876 GLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQ 935 G RC+ C Y+ I CQ C C +LG+ C ++GQC C P G+RC++C Sbjct: 517 GPRCDTCRSGFYSFPI-----CQACWCSALGSYQMP-CSSVTGQCECRPGVTGQRCDRCL 570 Query: 936 PGFYISP---GNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992 G Y P G+++ C P NS G C C+ + G C +CK Y+ Sbjct: 571 SGAYDFPHCQGSSSACDPAGT---------INSNLGYCQCK-LHVEGPTCSRCKLLYWNL 620 Query: 993 DPQT-GRCQPCNCHLSGALNET--CHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLG 1049 D + C C CH +G ++ T C G C CK V G CD C L+ +N G Sbjct: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFG 680 Query: 1050 C 1050 C Sbjct: 681 C 681 Score = 153 bits (386), Expect = 1e-36 Identities = 80/216 (37%), Positives = 105/216 (48%), Gaps = 28/216 (12%) Query: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTS 699 PC+C G C GGQC C+ +V GRQC +C G Y C PC+C Sbjct: 1265 PCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYGFPR-----CKPCSC--- 1314 Query: 700 GTVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCEPCQCNLHGSVN 756 G C + +GQC+C + +C+ C +F F + GCE C C+ G++ Sbjct: 1315 ----GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM-----AGCEGCNCSRRGTIE 1365 Query: 757 KF---CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813 C+ SGQC CK G QCD C FY C C+C+ G+ PG VC+ TG Sbjct: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPG-VCDPGTG 1422 Query: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849 C+CK NVEG +CN C EG+F+L N C C C Sbjct: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458 Score = 147 bits (372), Expect = 6e-35 Identities = 75/231 (32%), Positives = 109/231 (47%), Gaps = 24/231 (10%) Query: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFG-FK 734 C+N +L G PC C+ +G C GQC C+ NVIG +C C G + Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG 1305 Query: 735 FLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCK 793 F R C+PC C + C +GQC C QC+ C + + + C+ Sbjct: 1306 FPR------CKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCE 1354 Query: 794 ACDCDTAGSLPGTV--CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK 851 C+C G++ + C+ +GQC CKP + GRQC++C G + + C+PCNC++ Sbjct: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----CVPCNCNR 1409 Query: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902 GT G +C+ TG C CK V G CN C ++L N + C C C Sbjct: 1410 DGTEPG--VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458 Score = 142 bits (358), Expect = 3e-33 Identities = 81/261 (31%), Positives = 114/261 (43%), Gaps = 40/261 (15%) Query: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594 RCLC EG CD C + P Q A C+S + C Sbjct: 508 RCLCRPG--VEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC---------- 555 Query: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKD--YFFRQVGADPSAIDVCKPCDCDTVGTRNGS 652 +C TG+ C+ C Y F SA CD GT N + Sbjct: 556 ------------ECRPGVTGQRCDRCLSGAYDFPHCQGSSSA--------CDPAGTINSN 595 Query: 653 ILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNS 712 + G C CK HV G C++C+ ++NL + +P GCS C C+ +GTV G C Q Sbjct: 596 L------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGD 649 Query: 713 GQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEA 772 G C CK++V G CD C G+ L N GC+ CQC++ G+++ C+ SG C+C++ Sbjct: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709 Query: 773 KGLQCDTCRENFYGLDVTNCK 793 G C N+Y D+ + K Sbjct: 710 VGKVCQRPENNYYFPDLHHMK 730 Score = 138 bits (347), Expect = 5e-32 Identities = 107/351 (30%), Positives = 141/351 (40%), Gaps = 64/351 (18%) Query: 747 CQCNLHGSVNKFCNPHS-GQCECKKEAKGLQCDTCRENFYGL--------DVTNCKACDC 797 C CN H V NP +CEC+ G CD C + C+AC+C Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358 Query: 798 D--------------TAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSF 842 SL A G CI C+ N G C +C +G Y R Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKG--YYRPYGVP 416 Query: 843 L-----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN----LTIDN 893 + C+PC+CD C + +G+C CK G C +C YN L I Sbjct: 417 VDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472 Query: 894 FQ------------HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS 941 F + C+C+ G LP ICD G+CLC P +G RC+ C+ GFY Sbjct: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLP-EICDA-HGRCLCRPGVEGPRCDTCRSGFYSF 530 Query: 942 PGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQP 1001 P C C C G+ C+S+TGQC C+ + GQRCD+C + F G Sbjct: 531 PI----CQACWCSALGSYQMPCSSVTGQCECRPG-VTGQRCDRCLSGAYDFPHCQGSSSA 585 Query: 1002 CNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052 C+ +G +N G C CK V G C C +LD N GCS+ Sbjct: 586 CDP--AGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE 630 Score = 134 bits (337), Expect = 7e-31 Identities = 70/213 (32%), Positives = 98/213 (46%), Gaps = 28/213 (13%) Query: 584 CHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDC 643 CH + P H GG C C+ N GR C C + CKPC C Sbjct: 1268 CHPTGATGP----HCSPEGGQCP-CQPNVIGRQCTRCATGHY--------GFPRCKPCSC 1314 Query: 644 DTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVD 703 G LC+++ GQC C QC C+ ++ + GC CNC+ GT++ Sbjct: 1315 -------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMA--GCEGCNCSRRGTIE 1365 Query: 704 GDIT-CHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPH 762 + C ++SGQC+CK + G +CD C GF + C PC CN G+ C+P Sbjct: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGF-----YRFPECVPCNCNRDGTEPGVCDPG 1420 Query: 763 SGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795 +G C CK+ +G +C+ CRE + LD N K C Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGC 1453 Score = 130 bits (326), Expect = 1e-29 Identities = 70/211 (33%), Positives = 98/211 (46%), Gaps = 24/211 (11%) Query: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904 LPC C TG C+ GQCPC+ V G +C +C Y F C+ C C Sbjct: 1264 LPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG-----FPRCKPCSCGR 1316 Query: 905 LGTLPGTICDPISGQCLCVPNRQGRRCNQCQP-GFYISPGNATGCLPCSCHTTGAVNHI- 962 +C+ ++GQC C P +C C+ F P GC C+C G + Sbjct: 1317 ------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHP--MAGCEGCNCSRRGTIEAAM 1368 Query: 963 --CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020 C+ +GQC C+ I G++CD+C ++ F C PCNC+ G C TG Sbjct: 1369 PECDRDSGQCRCKPR-ITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGA 1423 Query: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051 C CK+ V G++C+ C + HLD NL GC+ Sbjct: 1424 CLCKENVEGTECNVCREGSFHLDPANLKGCT 1454 Score = 99.0 bits (245), Expect = 3e-20 Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 33/199 (16%) Query: 537 LCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE 596 +C+ G C C P Y +R +Y C PC CN HS C Sbjct: 1653 ICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQC------------ 1696 Query: 597 HFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCD 656 + G G+C +C+HNT G +CE C++ ++ + C+ C C T + + C Sbjct: 1697 --QDGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPH--TNSFATGCV 1747 Query: 657 QIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714 GG +C+CK +G QC +C G++ + C PC+CN++G + +CH +G Sbjct: 1748 VNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG---SCHPLTGD 1804 Query: 715 C---KCKANVIGLRCDHCN 730 C + K + CD C+ Sbjct: 1805 CINQEPKDSSPAEECDDCD 1823 Score = 87.4 bits (215), Expect = 1e-16 Identities = 51/158 (32%), Positives = 68/158 (43%), Gaps = 10/158 (6%) Query: 715 CKCKANVIGLRCDHCNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772 C C G C C+ G+ + + C PC CN H + C SG C C+ Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710 Query: 773 KGLQCDTCRENFYGLDVT-NCKACDCDTAGSLP-GTVCNAKTGQCICKPNVEGRQCNKCL 830 G C+ C+E +YG V +C+AC C S G V N +C CK G QC +C Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770 Query: 831 EGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC 868 G F Q C PC+C+ G + C+ TG C Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDC 1805 Score = 87.0 bits (214), Expect = 1e-16 Identities = 52/179 (29%), Positives = 77/179 (43%), Gaps = 18/179 (10%) Query: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCP-C 870 C C P G C C G Y R + C+PCNC+ S C +G C C Sbjct: 1654 CACPPAYAGDSCQGCSPG--YYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706 Query: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGR 929 + G C +C+ Y + C+ C C + G + + +C C G Sbjct: 1707 QHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764 Query: 930 RCNQCQPGFYISPGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDA--SIAGQRCDQC 985 +C +C PG++ +P G C PCSC++ G + C+ LTG C+ Q+ S + CD C Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822 Score = 85.1 bits (209), Expect = 5e-16 Identities = 61/183 (33%), Positives = 81/183 (44%), Gaps = 24/183 (13%) Query: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQ-HCQMCECDSLGTLPGTICDPISGQCL-CVPN 925 C C G C C P Y + C C C+ C SG C+ C N Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709 Query: 926 RQGRRCNQCQPGFYISPGNAT--GCLPCSC-HTTG-AVNHICNSLTGQCVCQDASIAGQR 981 G C +CQ G+Y GNA C C C HT A + N +C C+ A G + Sbjct: 1710 TAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCK-AGYTGTQ 1765 Query: 982 CDQCKDHYFGFDPQT--GRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS------KCD 1033 C++C YFG +PQ G CQPC+C+ +G L +CH +TG C ++ S CD Sbjct: 1766 CERCAPGYFG-NPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDCD 1823 Query: 1034 ACV 1036 +CV Sbjct: 1824 SCV 1826 Score = 82.8 bits (203), Expect = 2e-15 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 13/174 (7%) Query: 766 CECKKEAKGLQCDTCRENFY----GLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPN 820 C C G C C +Y GL C C+C+ + C +G C+ C+ N Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709 Query: 821 VEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN 880 G C +C EG + + S C C C T + + N +C CK G TG +C Sbjct: 1710 TAGEHCERCQEGYYGNAVHGS--CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767 Query: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934 +C P + CQ C C+S G L C P++G C+ + +C Sbjct: 1768 RCAPGYFGNPQKFGGSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEEC 1819 Score = 80.1 bits (196), Expect = 2e-14 Identities = 58/203 (28%), Positives = 77/203 (37%), Gaps = 33/203 (16%) Query: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPG 937 CN C H N D Q ++ G G G C+ C N G C QC G Sbjct: 356 CN-CHGHASNCYYDPDVERQQASLNTQGIYAG------GGVCINCQHNTAGVNCEQCAKG 408 Query: 938 FYISPGNAT----GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF- 992 +Y G GC+PCSC A C +G+C C+ + G C++C Y+ F Sbjct: 409 YYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKP-NFHGDNCEKCAIGYYNFP 465 Query: 993 ----------------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036 DP G + C+C+L G L E C G+C C+ V G +CD C Sbjct: 466 FCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCR 524 Query: 1037 PSASHLDVNNLLGCSKTPFQQPP 1059 + CS Q P Sbjct: 525 SGFYSFPICQACWCSALGSYQMP 547 Score = 79.0 bits (193), Expect = 3e-14 Identities = 53/182 (29%), Positives = 78/182 (42%), Gaps = 24/182 (13%) Query: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDV--CKPCDCDTVGTRNGSILCDQIGGQC-NC 664 C G +C+ C ++R D + C PC+C+ S C G C NC Sbjct: 1656 CPPAYAGDSCQGCSPGYYR----DHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706 Query: 665 KRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC-NTSGTVDGDITCHQNSG--QCKCKANV 721 + + +G C +CQ G+Y C C C +T+ G C N G +C CKA Sbjct: 1707 QHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGY 1761 Query: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC---ECKKEAKGLQCD 778 G +C+ C G+ C+PC CN +G + C+P +G C E K + +CD Sbjct: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECD 1820 Query: 779 TC 780 C Sbjct: 1821 DC 1822 Score = 75.5 bits (184), Expect = 4e-13 Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 8/122 (6%) Query: 920 CLCVPNRQGRRCNQCQPGFYIS-PGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDASI 977 C C P G C C PG+Y G TG C+PC+C+ G N C +G CV + Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNT 1710 Query: 978 AGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG--QCFCKQFVTGSKCDAC 1035 AG+ C++C++ Y+G + G C+ C C + + C + G +C CK TG++C+ C Sbjct: 1711 AGEHCERCQEGYYG-NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769 Query: 1036 VP 1037 P Sbjct: 1770 AP 1771 Score = 71.6 bits (174), Expect = 5e-12 Identities = 33/89 (37%), Positives = 46/89 (51%), Gaps = 10/89 (11%) Query: 947 GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006 G LPC CH TGA C+ GQC CQ ++ G++C +C ++GF RC+PC+C Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQ-PNVIGRQCTRCATGHYGFP----RCKPCSCG- 1315 Query: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDAC 1035 C +TGQC C +C+ C Sbjct: 1316 ----RRLCEEMTGQCRCPPRTVRPQCEVC 1340 Score = 58.2 bits (139), Expect = 6e-08 Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 38/182 (20%) Query: 506 YYAVDEITISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562 YY + +GRC C+GH++ C S C+ Q + T G HC+RC Y Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG--ICVNCQHN-TAGEHCERCQEGY------ 1722 Query: 563 QGDQVYAFNCKPCQC---NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL 619 G+ V+ +C+ C C NS + C N GG V C+ TG CE Sbjct: 1723 YGNAVHG-SCRACPCPHTNSFATGCVVN-------------GGDVRCSCKAGYTGTQCER 1768 Query: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC---NCKRHVSGRQCNQC 676 C +F G C+PC C++ G C + G C K +C+ C Sbjct: 1769 CAPGYF---GNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDCINQEPKDSSPAEECDDC 1822 Query: 677 QN 678 + Sbjct: 1823 DS 1824 >gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] Length = 3277 Score = 325 bits (833), Expect = 2e-88 Identities = 201/637 (31%), Positives = 297/637 (46%), Gaps = 61/637 (9%) Query: 338 EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFF-SPQPT 395 +AHP++ D W S ++ TQ N+ +++ L+ GQ + V YI+I+F SP+P Sbjct: 112 KAHPVTNAIDGSERW-WQSPPLSSGTQYNR---VNLTLDLGQLFHVAYILIKFANSPRPD 167 Query: 396 EIRIQRKKENSLDWEDWQYFARN----CGAFGMKNNGDLEKPDSVNCL-QLSNFTPYSRG 450 ++R + + WQYFA + FG + N + + D V C+ + S P G Sbjct: 168 LWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENG 227 Query: 451 NVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAVNL 502 V S++ N RPG NF + +L+EF KAT IR F H Sbjct: 228 EVVVSLI----NGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283 Query: 503 RHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562 R YY++ +I+I G+C C+GHA+ C+ + C + T G CDRC YN + +R Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343 Query: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVD----PFPFEHFRGGGGVCDDCEHNTTGRNCE 618 + C+ C C+ H+ +C+Y+ V+ + GGGVC +C+HNT G NCE Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403 Query: 619 LCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQN 678 C ++R G A D C PC CD C+Q G+C+CK + G C +C Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAI 459 Query: 679 GFYNL--------------QELDP--DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVI 722 G+YN DP C+CN G + H G+C C+ V Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH---GRCLCRPGVE 516 Query: 723 GLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRE 782 G RCD C GF ++ C+ C C+ GS C+ +GQCEC+ G +CD C Sbjct: 517 GPRCDTCRSGF-----YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLS 571 Query: 783 NFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF 842 Y + CD AG++ N+ G C CK +VEG C++C + L + N Sbjct: 572 GAYDFPHCQGSSSACDPAGTI-----NSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPS 626 Query: 843 LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902 C C C K GT++G+ C + G C CK V G C+ CE + L N+ CQ C+C Sbjct: 627 GCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQC 686 Query: 903 DSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY 939 D G L ++C SG C C + G+ C + + +Y Sbjct: 687 DIGGAL-SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722 Score = 160 bits (404), Expect = 1e-38 Identities = 85/239 (35%), Positives = 113/239 (47%), Gaps = 21/239 (8%) Query: 729 CNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLD 788 C + L +F G PC+C+ G+ C+P GQC C+ G QC C YG Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGF- 1306 Query: 789 VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCN 848 CK C C +C TGQC C P QC C +F C CN Sbjct: 1307 -PRCKPCSCGR------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAG--CEGCN 1357 Query: 849 CDKTGTINGSL-LCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT 907 C + GTI ++ C++ +GQC CK +TG +C++C Y F C C C+ GT Sbjct: 1358 CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY-----RFPECVPCNCNRDGT 1412 Query: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTTGAVNHICNS 965 PG +CDP +G CLC N +G CN C+ G F++ P N GC C C VN+ C+S Sbjct: 1413 EPG-VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCF---GVNNQCHS 1467 Score = 159 bits (403), Expect = 2e-38 Identities = 120/421 (28%), Positives = 176/421 (41%), Gaps = 76/421 (18%) Query: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739 +Y+++++ G C CN V +I + +C+C+ + G CD C G+ R Sbjct: 287 YYSIKDISIGG--QCVCNGHAEVC-NINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343 Query: 740 -----NDVGCEPCQCNLHGSVNKFCNPH----------------SGQC-ECKKEAKGLQC 777 CE C C+ H S N + +P G C C+ G+ C Sbjct: 344 PAAWEQSHECEACNCHGHAS-NCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNC 402 Query: 778 DTCRENFY---GLDVT---NCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831 + C + +Y G+ V C C CD + C +G+C CKPN G C KC Sbjct: 403 EQCAKGYYRPYGVPVDAPDGCIPCSCDPEHA---DGCEQGSGRCHCKPNFHGDNCEKCAI 459 Query: 832 GN----FYLRQNNSFLCLP------------CNCDKTGTINGSLLCNKSTGQCPCKLGVT 875 G F LR + P C+C+ G + +C+ + G+C C+ GV Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPE--ICD-AHGRCLCRPGVE 516 Query: 876 GLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQ 935 G RC+ C Y+ I CQ C C +LG+ C ++GQC C P G+RC++C Sbjct: 517 GPRCDTCRSGFYSFPI-----CQACWCSALGSYQMP-CSSVTGQCECRPGVTGQRCDRCL 570 Query: 936 PGFYISP---GNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992 G Y P G+++ C P NS G C C+ + G C +CK Y+ Sbjct: 571 SGAYDFPHCQGSSSACDPAGT---------INSNLGYCQCK-LHVEGPTCSRCKLLYWNL 620 Query: 993 DPQT-GRCQPCNCHLSGALNET--CHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLG 1049 D + C C CH +G ++ T C G C CK V G CD C L+ +N G Sbjct: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFG 680 Query: 1050 C 1050 C Sbjct: 681 C 681 Score = 153 bits (386), Expect = 1e-36 Identities = 80/216 (37%), Positives = 105/216 (48%), Gaps = 28/216 (12%) Query: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTS 699 PC+C G C GGQC C+ +V GRQC +C G Y C PC+C Sbjct: 1265 PCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYGFPR-----CKPCSC--- 1314 Query: 700 GTVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCEPCQCNLHGSVN 756 G C + +GQC+C + +C+ C +F F + GCE C C+ G++ Sbjct: 1315 ----GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM-----AGCEGCNCSRRGTIE 1365 Query: 757 KF---CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813 C+ SGQC CK G QCD C FY C C+C+ G+ PG VC+ TG Sbjct: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPG-VCDPGTG 1422 Query: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849 C+CK NVEG +CN C EG+F+L N C C C Sbjct: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458 Score = 147 bits (372), Expect = 6e-35 Identities = 75/231 (32%), Positives = 109/231 (47%), Gaps = 24/231 (10%) Query: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFG-FK 734 C+N +L G PC C+ +G C GQC C+ NVIG +C C G + Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG 1305 Query: 735 FLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCK 793 F R C+PC C + C +GQC C QC+ C + + + C+ Sbjct: 1306 FPR------CKPCSCG-----RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCE 1354 Query: 794 ACDCDTAGSLPGTV--CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK 851 C+C G++ + C+ +GQC CKP + GRQC++C G + + C+PCNC++ Sbjct: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----CVPCNCNR 1409 Query: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902 GT G +C+ TG C CK V G CN C ++L N + C C C Sbjct: 1410 DGTEPG--VCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458 Score = 142 bits (358), Expect = 3e-33 Identities = 81/261 (31%), Positives = 114/261 (43%), Gaps = 40/261 (15%) Query: 535 RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFP 594 RCLC EG CD C + P Q A C+S + C Sbjct: 508 RCLCRPG--VEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC---------- 555 Query: 595 FEHFRGGGGVCDDCEHNTTGRNCELCKD--YFFRQVGADPSAIDVCKPCDCDTVGTRNGS 652 +C TG+ C+ C Y F SA CD GT N + Sbjct: 556 ------------ECRPGVTGQRCDRCLSGAYDFPHCQGSSSA--------CDPAGTINSN 595 Query: 653 ILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNS 712 + G C CK HV G C++C+ ++NL + +P GCS C C+ +GTV G C Q Sbjct: 596 L------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGD 649 Query: 713 GQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEA 772 G C CK++V G CD C G+ L N GC+ CQC++ G+++ C+ SG C+C++ Sbjct: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709 Query: 773 KGLQCDTCRENFYGLDVTNCK 793 G C N+Y D+ + K Sbjct: 710 VGKVCQRPENNYYFPDLHHMK 730 Score = 138 bits (347), Expect = 5e-32 Identities = 107/351 (30%), Positives = 141/351 (40%), Gaps = 64/351 (18%) Query: 747 CQCNLHGSVNKFCNPHS-GQCECKKEAKGLQCDTCRENFYGL--------DVTNCKACDC 797 C CN H V NP +CEC+ G CD C + C+AC+C Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358 Query: 798 D--------------TAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSF 842 SL A G CI C+ N G C +C +G Y R Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKG--YYRPYGVP 416 Query: 843 L-----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYN----LTIDN 893 + C+PC+CD C + +G+C CK G C +C YN L I Sbjct: 417 VDAPDGCIPCSCDPEHADG----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472 Query: 894 FQ------------HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS 941 F + C+C+ G LP ICD G+CLC P +G RC+ C+ GFY Sbjct: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLP-EICDA-HGRCLCRPGVEGPRCDTCRSGFYSF 530 Query: 942 PGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQP 1001 P C C C G+ C+S+TGQC C+ + GQRCD+C + F G Sbjct: 531 PI----CQACWCSALGSYQMPCSSVTGQCECRPG-VTGQRCDRCLSGAYDFPHCQGSSSA 585 Query: 1002 CNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052 C+ +G +N G C CK V G C C +LD N GCS+ Sbjct: 586 CDP--AGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE 630 Score = 134 bits (337), Expect = 7e-31 Identities = 70/213 (32%), Positives = 98/213 (46%), Gaps = 28/213 (13%) Query: 584 CHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDC 643 CH + P H GG C C+ N GR C C + CKPC C Sbjct: 1268 CHPTGATGP----HCSPEGGQCP-CQPNVIGRQCTRCATGHY--------GFPRCKPCSC 1314 Query: 644 DTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVD 703 G LC+++ GQC C QC C+ ++ + GC CNC+ GT++ Sbjct: 1315 -------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMA--GCEGCNCSRRGTIE 1365 Query: 704 GDIT-CHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPH 762 + C ++SGQC+CK + G +CD C GF + C PC CN G+ C+P Sbjct: 1366 AAMPECDRDSGQCRCKPRITGRQCDRCASGF-----YRFPECVPCNCNRDGTEPGVCDPG 1420 Query: 763 SGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795 +G C CK+ +G +C+ CRE + LD N K C Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGC 1453 Score = 130 bits (326), Expect = 1e-29 Identities = 70/211 (33%), Positives = 98/211 (46%), Gaps = 24/211 (11%) Query: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904 LPC C TG C+ GQCPC+ V G +C +C Y F C+ C C Sbjct: 1264 LPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYG-----FPRCKPCSCGR 1316 Query: 905 LGTLPGTICDPISGQCLCVPNRQGRRCNQCQP-GFYISPGNATGCLPCSCHTTGAVNHI- 962 +C+ ++GQC C P +C C+ F P GC C+C G + Sbjct: 1317 ------RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHP--MAGCEGCNCSRRGTIEAAM 1368 Query: 963 --CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQ 1020 C+ +GQC C+ I G++CD+C ++ F C PCNC+ G C TG Sbjct: 1369 PECDRDSGQCRCKPR-ITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGA 1423 Query: 1021 CFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051 C CK+ V G++C+ C + HLD NL GC+ Sbjct: 1424 CLCKENVEGTECNVCREGSFHLDPANLKGCT 1454 Score = 99.0 bits (245), Expect = 3e-20 Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 33/199 (16%) Query: 537 LCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE 596 +C+ G C C P Y +R +Y C PC CN HS C Sbjct: 1653 ICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQC------------ 1696 Query: 597 HFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCD 656 + G G+C +C+HNT G +CE C++ ++ + C+ C C T + + C Sbjct: 1697 --QDGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPH--TNSFATGCV 1747 Query: 657 QIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714 GG +C+CK +G QC +C G++ + C PC+CN++G + +CH +G Sbjct: 1748 VNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG---SCHPLTGD 1804 Query: 715 C---KCKANVIGLRCDHCN 730 C + K + CD C+ Sbjct: 1805 CINQEPKDSSPAEECDDCD 1823 Score = 87.4 bits (215), Expect = 1e-16 Identities = 51/158 (32%), Positives = 68/158 (43%), Gaps = 10/158 (6%) Query: 715 CKCKANVIGLRCDHCNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772 C C G C C+ G+ + + C PC CN H + C SG C C+ Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHNT 1710 Query: 773 KGLQCDTCRENFYGLDVT-NCKACDCDTAGSLP-GTVCNAKTGQCICKPNVEGRQCNKCL 830 G C+ C+E +YG V +C+AC C S G V N +C CK G QC +C Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770 Query: 831 EGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC 868 G F Q C PC+C+ G + C+ TG C Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDC 1805 Score = 87.0 bits (214), Expect = 1e-16 Identities = 52/179 (29%), Positives = 77/179 (43%), Gaps = 18/179 (10%) Query: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCP-C 870 C C P G C C G Y R + C+PCNC+ S C +G C C Sbjct: 1654 CACPPAYAGDSCQGCSPG--YYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706 Query: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGR 929 + G C +C+ Y + C+ C C + G + + +C C G Sbjct: 1707 QHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764 Query: 930 RCNQCQPGFYISPGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDA--SIAGQRCDQC 985 +C +C PG++ +P G C PCSC++ G + C+ LTG C+ Q+ S + CD C Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 1822 Score = 85.1 bits (209), Expect = 5e-16 Identities = 61/183 (33%), Positives = 81/183 (44%), Gaps = 24/183 (13%) Query: 868 CPCKLGVTGLRCNQCEPHRYNLTIDNFQ-HCQMCECDSLGTLPGTICDPISGQCL-CVPN 925 C C G C C P Y + C C C+ C SG C+ C N Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709 Query: 926 RQGRRCNQCQPGFYISPGNAT--GCLPCSC-HTTG-AVNHICNSLTGQCVCQDASIAGQR 981 G C +CQ G+Y GNA C C C HT A + N +C C+ A G + Sbjct: 1710 TAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCK-AGYTGTQ 1765 Query: 982 CDQCKDHYFGFDPQT--GRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS------KCD 1033 C++C YFG +PQ G CQPC+C+ +G L +CH +TG C ++ S CD Sbjct: 1766 CERCAPGYFG-NPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDCD 1823 Query: 1034 ACV 1036 +CV Sbjct: 1824 SCV 1826 Score = 82.8 bits (203), Expect = 2e-15 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 13/174 (7%) Query: 766 CECKKEAKGLQCDTCRENFY----GLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPN 820 C C G C C +Y GL C C+C+ + C +G C+ C+ N Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHN 1709 Query: 821 VEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN 880 G C +C EG + + S C C C T + + N +C CK G TG +C Sbjct: 1710 TAGEHCERCQEGYYGNAVHGS--CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767 Query: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934 +C P + CQ C C+S G L C P++G C+ + +C Sbjct: 1768 RCAPGYFGNPQKFGGSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEEC 1819 Score = 80.1 bits (196), Expect = 2e-14 Identities = 58/203 (28%), Positives = 77/203 (37%), Gaps = 33/203 (16%) Query: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPG 937 CN C H N D Q ++ G G G C+ C N G C QC G Sbjct: 356 CN-CHGHASNCYYDPDVERQQASLNTQGIYAG------GGVCINCQHNTAGVNCEQCAKG 408 Query: 938 FYISPGNAT----GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF- 992 +Y G GC+PCSC A C +G+C C+ + G C++C Y+ F Sbjct: 409 YYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKP-NFHGDNCEKCAIGYYNFP 465 Query: 993 ----------------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036 DP G + C+C+L G L E C G+C C+ V G +CD C Sbjct: 466 FCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCR 524 Query: 1037 PSASHLDVNNLLGCSKTPFQQPP 1059 + CS Q P Sbjct: 525 SGFYSFPICQACWCSALGSYQMP 547 Score = 79.0 bits (193), Expect = 3e-14 Identities = 53/182 (29%), Positives = 78/182 (42%), Gaps = 24/182 (13%) Query: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDV--CKPCDCDTVGTRNGSILCDQIGGQC-NC 664 C G +C+ C ++R D + C PC+C+ S C G C NC Sbjct: 1656 CPPAYAGDSCQGCSPGYYR----DHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNC 1706 Query: 665 KRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC-NTSGTVDGDITCHQNSG--QCKCKANV 721 + + +G C +CQ G+Y C C C +T+ G C N G +C CKA Sbjct: 1707 QHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGY 1761 Query: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC---ECKKEAKGLQCD 778 G +C+ C G+ C+PC CN +G + C+P +G C E K + +CD Sbjct: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECD 1820 Query: 779 TC 780 C Sbjct: 1821 DC 1822 Score = 75.5 bits (184), Expect = 4e-13 Identities = 42/122 (34%), Positives = 63/122 (51%), Gaps = 8/122 (6%) Query: 920 CLCVPNRQGRRCNQCQPGFYIS-PGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDASI 977 C C P G C C PG+Y G TG C+PC+C+ G N C +G CV + Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNT 1710 Query: 978 AGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG--QCFCKQFVTGSKCDAC 1035 AG+ C++C++ Y+G + G C+ C C + + C + G +C CK TG++C+ C Sbjct: 1711 AGEHCERCQEGYYG-NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769 Query: 1036 VP 1037 P Sbjct: 1770 AP 1771 Score = 71.6 bits (174), Expect = 5e-12 Identities = 33/89 (37%), Positives = 46/89 (51%), Gaps = 10/89 (11%) Query: 947 GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006 G LPC CH TGA C+ GQC CQ ++ G++C +C ++GF RC+PC+C Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQ-PNVIGRQCTRCATGHYGFP----RCKPCSCG- 1315 Query: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDAC 1035 C +TGQC C +C+ C Sbjct: 1316 ----RRLCEEMTGQCRCPPRTVRPQCEVC 1340 Score = 58.2 bits (139), Expect = 6e-08 Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 38/182 (20%) Query: 506 YYAVDEITISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562 YY + +GRC C+GH++ C S C+ Q + T G HC+RC Y Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG--ICVNCQHN-TAGEHCERCQEGY------ 1722 Query: 563 QGDQVYAFNCKPCQC---NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL 619 G+ V+ +C+ C C NS + C N GG V C+ TG CE Sbjct: 1723 YGNAVHG-SCRACPCPHTNSFATGCVVN-------------GGDVRCSCKAGYTGTQCER 1768 Query: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC---NCKRHVSGRQCNQC 676 C +F G C+PC C++ G C + G C K +C+ C Sbjct: 1769 CAPGYF---GNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDCINQEPKDSSPAEECDDC 1822 Query: 677 QN 678 + Sbjct: 1823 DS 1824 >gi|62868217 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 298 bits (762), Expect = 4e-80 Identities = 164/499 (32%), Positives = 253/499 (50%), Gaps = 38/499 (7%) Query: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGMKNN 427 V++ +DL+ ++Q+ ++++F P P + I+R + W +QY A +C F Sbjct: 104 VSLQLDLDR-RFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQ 162 Query: 428 GDLEKPDSVNCLQLSNFTPYSR---GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484 G + V C L P +R G V +++ + +QE + T Sbjct: 163 GRPQSWQDVRCQSLPQ-RPNARLNGGKVQLNLMDLVSGIPATQSQ-----KIQEVGEITN 216 Query: 485 IRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNC---------DTTSQPYR 535 +R +F + + YYAV ++ + G C CHGHAD C +T+ Sbjct: 217 LRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVH 276 Query: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595 +C + T G +C+RC P YN++P+R + A C+ C CN HS++CH+ DP F Sbjct: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF----DPAVF 332 Query: 596 EHFRGG-GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654 +G GGVCD+C +T G+NCE C+ ++FR S + C C+CD G G+ Sbjct: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-P 391 Query: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714 CD + GQC CK HV G +C+ C+ GF L +P GC C+CN G+ D+ C + SG+ Sbjct: 392 CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS-RRDMPCDEESGR 450 Query: 715 CKCKANVIGLRCDHC-NFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAK 773 C C NV+G +CD C + +K + GCEPC C+ H S++ CN +GQC C++ Sbjct: 451 CLCLPNVVGPKCDQCAPYHWKLA---SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFG 507 Query: 774 GLQCDT-----CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828 GL C C + YG T C+ACDCD G+ G C+ +G+C+C+P + G +C++ Sbjct: 508 GLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT-EGPGCDKASGRCLCRPGLTGPRCDQ 566 Query: 829 CLEGNFYLRQNNSFLCLPC 847 C G + R C PC Sbjct: 567 CQRG-YCNRYPVCVACHPC 584 Score = 179 bits (453), Expect = 2e-44 Identities = 110/336 (32%), Positives = 154/336 (45%), Gaps = 46/336 (13%) Query: 647 GTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN------LQELDPDGCSPCNCNTSG 700 G G Q+ C C+ + +G C +C FYN + D C C+CN Sbjct: 264 GASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHS 322 Query: 701 TVDGDITCHQN-----------SGQC-KCKANVIGLRCDHCNFGFKFLR----SFNDVGC 744 TCH + G C C+ + G C+ C + R S + C Sbjct: 323 E-----TCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET-C 376 Query: 745 EPCQCNLHGSV-NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTA 800 C+C+ G+V C+P +GQC CK+ +G +CD C+ F GL N C CDC+ Sbjct: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436 Query: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860 GS C+ ++G+C+C PNV G +C++C ++ L C PC CD +++ Sbjct: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQ-- 492 Query: 861 CNKSTGQCPCKLGVTGLRCN-----QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDP 915 CN+ TGQCPC+ G GL C+ QC Y D C+ C+CD GT G CD Sbjct: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDCDFRGT-EGPGCDK 548 Query: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951 SG+CLC P G RC+QCQ G+ C PC Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584 Score = 177 bits (449), Expect = 7e-44 Identities = 107/325 (32%), Positives = 150/325 (46%), Gaps = 45/325 (13%) Query: 749 CNLHGSVNKFCNPHSGQ-------------CECKKEAKGLQCDTCRENFY---------G 786 C HG ++ C P G C C+ G C+ C FY G Sbjct: 250 CFCHGHADR-CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEG 307 Query: 787 LDVTNCKACDC----DTAGSLPGTVC---NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQ 838 D C+ CDC +T P A G C C+ + EG+ C +C F R+ Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367 Query: 839 NNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895 + + C+ C CD G + G+ C+ TGQC CK V G RC+ C+P LT N Q Sbjct: 368 PGASIQETCISCECDPDGAVPGAP-CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQ 426 Query: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHT 955 C C+C+ LG+ CD SG+CLC+PN G +C+QC P ++ + GC PC+C Sbjct: 427 GCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDP 485 Query: 956 TGAVNHICNSLTGQCVCQDASIAGQRCD-----QCKDHYFGFDPQTGRCQPCNCHLSGAL 1010 +++ CN TGQC C++ G C QC D +G D TG C+ C+C G Sbjct: 486 HNSLSPQCNQFTGQCPCRE-GFGGLMCSAAAIRQCPDRTYG-DVATG-CRACDCDFRGTE 542 Query: 1011 NETCHLVTGQCFCKQFVTGSKCDAC 1035 C +G+C C+ +TG +CD C Sbjct: 543 GPGCDKASGRCLCRPGLTGPRCDQC 567 Score = 91.3 bits (225), Expect = 7e-18 Identities = 60/199 (30%), Positives = 90/199 (45%), Gaps = 39/199 (19%) Query: 868 CPCKLGVTGLRCNQCEPHRYNLTI-----DNFQHCQMCECD---------------SLGT 907 C C+ G C +C P N + CQ C+C+ S G Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338 Query: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS--PGNATG--CLPCSCHTTGAVNHI- 962 G +CD C + +G+ C +CQ ++ + PG + C+ C C GAV Sbjct: 339 YGG-VCDN------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAP 391 Query: 963 CNSLTGQCVCQDASIAGQRCDQCKDHYFGF---DPQTGRCQPCNCHLSGALNET-CHLVT 1018 C+ +TGQCVC++ + G+RCD CK + G +PQ C C+C++ G+ + C + Sbjct: 392 CDPVTGQCVCKE-HVQGERCDLCKPGFTGLTYANPQG--CHRCDCNILGSRRDMPCDEES 448 Query: 1019 GQCFCKQFVTGSKCDACVP 1037 G+C C V G KCD C P Sbjct: 449 GRCLCLPNVVGPKCDQCAP 467 Score = 72.0 bits (175), Expect = 4e-12 Identities = 52/182 (28%), Positives = 73/182 (40%), Gaps = 40/182 (21%) Query: 903 DSLGTLPGTICDP-----ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC 951 D PG P + C+C N G C +C P + P +A C C Sbjct: 257 DRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRC 316 Query: 952 SCH---------------TTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF-----G 991 C+ + GA +C++ C+D + G+ C++C+ HYF G Sbjct: 317 DCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHT-EGKNCERCQLHYFRNRRPG 369 Query: 992 FDPQTGRCQPCNCHLSGAL-NETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 Q C C C GA+ C VTGQC CK+ V G +CD C P + L N GC Sbjct: 370 ASIQE-TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428 Query: 1051 SK 1052 + Sbjct: 429 HR 430 >gi|62868215 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 298 bits (762), Expect = 4e-80 Identities = 164/499 (32%), Positives = 253/499 (50%), Gaps = 38/499 (7%) Query: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGMKNN 427 V++ +DL+ ++Q+ ++++F P P + I+R + W +QY A +C F Sbjct: 104 VSLQLDLDR-RFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQ 162 Query: 428 GDLEKPDSVNCLQLSNFTPYSR---GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484 G + V C L P +R G V +++ + +QE + T Sbjct: 163 GRPQSWQDVRCQSLPQ-RPNARLNGGKVQLNLMDLVSGIPATQSQ-----KIQEVGEITN 216 Query: 485 IRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNC---------DTTSQPYR 535 +R +F + + YYAV ++ + G C CHGHAD C +T+ Sbjct: 217 LRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVH 276 Query: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595 +C + T G +C+RC P YN++P+R + A C+ C CN HS++CH+ DP F Sbjct: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF----DPAVF 332 Query: 596 EHFRGG-GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654 +G GGVCD+C +T G+NCE C+ ++FR S + C C+CD G G+ Sbjct: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-P 391 Query: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714 CD + GQC CK HV G +C+ C+ GF L +P GC C+CN G+ D+ C + SG+ Sbjct: 392 CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS-RRDMPCDEESGR 450 Query: 715 CKCKANVIGLRCDHC-NFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAK 773 C C NV+G +CD C + +K + GCEPC C+ H S++ CN +GQC C++ Sbjct: 451 CLCLPNVVGPKCDQCAPYHWKLA---SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFG 507 Query: 774 GLQCDT-----CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828 GL C C + YG T C+ACDCD G+ G C+ +G+C+C+P + G +C++ Sbjct: 508 GLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT-EGPGCDKASGRCLCRPGLTGPRCDQ 566 Query: 829 CLEGNFYLRQNNSFLCLPC 847 C G + R C PC Sbjct: 567 CQRG-YCNRYPVCVACHPC 584 Score = 179 bits (453), Expect = 2e-44 Identities = 110/336 (32%), Positives = 154/336 (45%), Gaps = 46/336 (13%) Query: 647 GTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN------LQELDPDGCSPCNCNTSG 700 G G Q+ C C+ + +G C +C FYN + D C C+CN Sbjct: 264 GASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHS 322 Query: 701 TVDGDITCHQN-----------SGQC-KCKANVIGLRCDHCNFGFKFLR----SFNDVGC 744 TCH + G C C+ + G C+ C + R S + C Sbjct: 323 E-----TCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET-C 376 Query: 745 EPCQCNLHGSV-NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTA 800 C+C+ G+V C+P +GQC CK+ +G +CD C+ F GL N C CDC+ Sbjct: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436 Query: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860 GS C+ ++G+C+C PNV G +C++C ++ L C PC CD +++ Sbjct: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQ-- 492 Query: 861 CNKSTGQCPCKLGVTGLRCN-----QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDP 915 CN+ TGQCPC+ G GL C+ QC Y D C+ C+CD GT G CD Sbjct: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDCDFRGT-EGPGCDK 548 Query: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951 SG+CLC P G RC+QCQ G+ C PC Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584 Score = 177 bits (449), Expect = 7e-44 Identities = 107/325 (32%), Positives = 150/325 (46%), Gaps = 45/325 (13%) Query: 749 CNLHGSVNKFCNPHSGQ-------------CECKKEAKGLQCDTCRENFY---------G 786 C HG ++ C P G C C+ G C+ C FY G Sbjct: 250 CFCHGHADR-CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEG 307 Query: 787 LDVTNCKACDC----DTAGSLPGTVC---NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQ 838 D C+ CDC +T P A G C C+ + EG+ C +C F R+ Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367 Query: 839 NNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895 + + C+ C CD G + G+ C+ TGQC CK V G RC+ C+P LT N Q Sbjct: 368 PGASIQETCISCECDPDGAVPGAP-CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQ 426 Query: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHT 955 C C+C+ LG+ CD SG+CLC+PN G +C+QC P ++ + GC PC+C Sbjct: 427 GCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDP 485 Query: 956 TGAVNHICNSLTGQCVCQDASIAGQRCD-----QCKDHYFGFDPQTGRCQPCNCHLSGAL 1010 +++ CN TGQC C++ G C QC D +G D TG C+ C+C G Sbjct: 486 HNSLSPQCNQFTGQCPCRE-GFGGLMCSAAAIRQCPDRTYG-DVATG-CRACDCDFRGTE 542 Query: 1011 NETCHLVTGQCFCKQFVTGSKCDAC 1035 C +G+C C+ +TG +CD C Sbjct: 543 GPGCDKASGRCLCRPGLTGPRCDQC 567 Score = 91.3 bits (225), Expect = 7e-18 Identities = 60/199 (30%), Positives = 90/199 (45%), Gaps = 39/199 (19%) Query: 868 CPCKLGVTGLRCNQCEPHRYNLTI-----DNFQHCQMCECD---------------SLGT 907 C C+ G C +C P N + CQ C+C+ S G Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338 Query: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS--PGNATG--CLPCSCHTTGAVNHI- 962 G +CD C + +G+ C +CQ ++ + PG + C+ C C GAV Sbjct: 339 YGG-VCDN------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAP 391 Query: 963 CNSLTGQCVCQDASIAGQRCDQCKDHYFGF---DPQTGRCQPCNCHLSGALNET-CHLVT 1018 C+ +TGQCVC++ + G+RCD CK + G +PQ C C+C++ G+ + C + Sbjct: 392 CDPVTGQCVCKE-HVQGERCDLCKPGFTGLTYANPQG--CHRCDCNILGSRRDMPCDEES 448 Query: 1019 GQCFCKQFVTGSKCDACVP 1037 G+C C V G KCD C P Sbjct: 449 GRCLCLPNVVGPKCDQCAP 467 Score = 72.0 bits (175), Expect = 4e-12 Identities = 52/182 (28%), Positives = 73/182 (40%), Gaps = 40/182 (21%) Query: 903 DSLGTLPGTICDP-----ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC 951 D PG P + C+C N G C +C P + P +A C C Sbjct: 257 DRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRC 316 Query: 952 SCH---------------TTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF-----G 991 C+ + GA +C++ C+D + G+ C++C+ HYF G Sbjct: 317 DCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHT-EGKNCERCQLHYFRNRRPG 369 Query: 992 FDPQTGRCQPCNCHLSGAL-NETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 Q C C C GA+ C VTGQC CK+ V G +CD C P + L N GC Sbjct: 370 ASIQE-TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428 Query: 1051 SK 1052 + Sbjct: 429 HR 430 >gi|189083719 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 298 bits (762), Expect = 4e-80 Identities = 164/499 (32%), Positives = 253/499 (50%), Gaps = 38/499 (7%) Query: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGMKNN 427 V++ +DL+ ++Q+ ++++F P P + I+R + W +QY A +C F Sbjct: 104 VSLQLDLDR-RFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQ 162 Query: 428 GDLEKPDSVNCLQLSNFTPYSR---GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484 G + V C L P +R G V +++ + +QE + T Sbjct: 163 GRPQSWQDVRCQSLPQ-RPNARLNGGKVQLNLMDLVSGIPATQSQ-----KIQEVGEITN 216 Query: 485 IRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNC---------DTTSQPYR 535 +R +F + + YYAV ++ + G C CHGHAD C +T+ Sbjct: 217 LRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVH 276 Query: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595 +C + T G +C+RC P YN++P+R + A C+ C CN HS++CH+ DP F Sbjct: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF----DPAVF 332 Query: 596 EHFRGG-GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654 +G GGVCD+C +T G+NCE C+ ++FR S + C C+CD G G+ Sbjct: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-P 391 Query: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714 CD + GQC CK HV G +C+ C+ GF L +P GC C+CN G+ D+ C + SG+ Sbjct: 392 CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS-RRDMPCDEESGR 450 Query: 715 CKCKANVIGLRCDHC-NFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAK 773 C C NV+G +CD C + +K + GCEPC C+ H S++ CN +GQC C++ Sbjct: 451 CLCLPNVVGPKCDQCAPYHWKLA---SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFG 507 Query: 774 GLQCDT-----CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828 GL C C + YG T C+ACDCD G+ G C+ +G+C+C+P + G +C++ Sbjct: 508 GLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT-EGPGCDKASGRCLCRPGLTGPRCDQ 566 Query: 829 CLEGNFYLRQNNSFLCLPC 847 C G + R C PC Sbjct: 567 CQRG-YCNRYPVCVACHPC 584 Score = 179 bits (453), Expect = 2e-44 Identities = 110/336 (32%), Positives = 154/336 (45%), Gaps = 46/336 (13%) Query: 647 GTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN------LQELDPDGCSPCNCNTSG 700 G G Q+ C C+ + +G C +C FYN + D C C+CN Sbjct: 264 GASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHS 322 Query: 701 TVDGDITCHQN-----------SGQC-KCKANVIGLRCDHCNFGFKFLR----SFNDVGC 744 TCH + G C C+ + G C+ C + R S + C Sbjct: 323 E-----TCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET-C 376 Query: 745 EPCQCNLHGSV-NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTA 800 C+C+ G+V C+P +GQC CK+ +G +CD C+ F GL N C CDC+ Sbjct: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436 Query: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860 GS C+ ++G+C+C PNV G +C++C ++ L C PC CD +++ Sbjct: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQ-- 492 Query: 861 CNKSTGQCPCKLGVTGLRCN-----QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDP 915 CN+ TGQCPC+ G GL C+ QC Y D C+ C+CD GT G CD Sbjct: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDCDFRGT-EGPGCDK 548 Query: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951 SG+CLC P G RC+QCQ G+ C PC Sbjct: 549 ASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584 Score = 177 bits (449), Expect = 7e-44 Identities = 107/325 (32%), Positives = 150/325 (46%), Gaps = 45/325 (13%) Query: 749 CNLHGSVNKFCNPHSGQ-------------CECKKEAKGLQCDTCRENFY---------G 786 C HG ++ C P G C C+ G C+ C FY G Sbjct: 250 CFCHGHADR-CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEG 307 Query: 787 LDVTNCKACDC----DTAGSLPGTVC---NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQ 838 D C+ CDC +T P A G C C+ + EG+ C +C F R+ Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367 Query: 839 NNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895 + + C+ C CD G + G+ C+ TGQC CK V G RC+ C+P LT N Q Sbjct: 368 PGASIQETCISCECDPDGAVPGAP-CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQ 426 Query: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHT 955 C C+C+ LG+ CD SG+CLC+PN G +C+QC P ++ + GC PC+C Sbjct: 427 GCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDP 485 Query: 956 TGAVNHICNSLTGQCVCQDASIAGQRCD-----QCKDHYFGFDPQTGRCQPCNCHLSGAL 1010 +++ CN TGQC C++ G C QC D +G D TG C+ C+C G Sbjct: 486 HNSLSPQCNQFTGQCPCRE-GFGGLMCSAAAIRQCPDRTYG-DVATG-CRACDCDFRGTE 542 Query: 1011 NETCHLVTGQCFCKQFVTGSKCDAC 1035 C +G+C C+ +TG +CD C Sbjct: 543 GPGCDKASGRCLCRPGLTGPRCDQC 567 Score = 91.3 bits (225), Expect = 7e-18 Identities = 60/199 (30%), Positives = 90/199 (45%), Gaps = 39/199 (19%) Query: 868 CPCKLGVTGLRCNQCEPHRYNLTI-----DNFQHCQMCECD---------------SLGT 907 C C+ G C +C P N + CQ C+C+ S G Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338 Query: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS--PGNATG--CLPCSCHTTGAVNHI- 962 G +CD C + +G+ C +CQ ++ + PG + C+ C C GAV Sbjct: 339 YGG-VCDN------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAP 391 Query: 963 CNSLTGQCVCQDASIAGQRCDQCKDHYFGF---DPQTGRCQPCNCHLSGALNET-CHLVT 1018 C+ +TGQCVC++ + G+RCD CK + G +PQ C C+C++ G+ + C + Sbjct: 392 CDPVTGQCVCKE-HVQGERCDLCKPGFTGLTYANPQG--CHRCDCNILGSRRDMPCDEES 448 Query: 1019 GQCFCKQFVTGSKCDACVP 1037 G+C C V G KCD C P Sbjct: 449 GRCLCLPNVVGPKCDQCAP 467 Score = 72.0 bits (175), Expect = 4e-12 Identities = 52/182 (28%), Positives = 73/182 (40%), Gaps = 40/182 (21%) Query: 903 DSLGTLPGTICDP-----ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC 951 D PG P + C+C N G C +C P + P +A C C Sbjct: 257 DRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRC 316 Query: 952 SCH---------------TTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF-----G 991 C+ + GA +C++ C+D + G+ C++C+ HYF G Sbjct: 317 DCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHT-EGKNCERCQLHYFRNRRPG 369 Query: 992 FDPQTGRCQPCNCHLSGAL-NETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 Q C C C GA+ C VTGQC CK+ V G +CD C P + L N GC Sbjct: 370 ASIQE-TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428 Query: 1051 SK 1052 + Sbjct: 429 HR 430 >gi|167614504 laminin, beta 1 precursor [Homo sapiens] Length = 1786 Score = 277 bits (708), Expect = 7e-74 Identities = 162/482 (33%), Positives = 240/482 (49%), Gaps = 53/482 (10%) Query: 335 LNPEAHPLSFVNDNDVGTSWVSNVFTNITQLNQGV---TISVDLENGQYQVFYIIIQFFS 391 LNP++H + +V T++ N Q GV TI +DLE ++ ++I+ F + Sbjct: 89 LNPDSHLIE-----NVVTTFAPNRLKIWWQSENGVENVTIQLDLE-AEFHFTHLIMTFKT 142 Query: 392 PQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNGDLEKPDSVNC-LQLSNFTPYSR 449 +P + I+R + W ++YFA +C A F + G ++K D + C + S+ P + Sbjct: 143 FRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTE 202 Query: 450 GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR---- 505 G V F L P Y+ P +Q +K T +R F + + ++ R Sbjct: 203 GEVIFRALDPAFKIEDPYS-----PRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREK 257 Query: 506 -YYAVDEITISGRCQCHGHADNC---DTTSQPYR------CLCSQESFTEGLHCDRCLPL 555 YYAV ++ + G C C+GHA C D ++ C+C T+GL+C+ C+ Sbjct: 258 YYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHN--TKGLNCELCMDF 315 Query: 556 YNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGR 615 Y+D P+R + + CK C CN HS SCH++++V GGVCDDC+HNT GR Sbjct: 316 YHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVY---LATGNVSGGVCDDCQHNTMGR 372 Query: 616 NCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ--------IGGQCNCKRH 667 NCE CK ++++ D + C+ C CD G++N I CD I GQC CK + Sbjct: 373 NCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGI-CDSYTDFSTGLIAGQCRCKLN 431 Query: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727 V G C+ C+ GFY+L DP GC C CN GT+ G C +G C CK V G CD Sbjct: 432 VEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD 491 Query: 728 HC---NFGFKFLRSFNDV-GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCREN 783 C ++G ND+ GC PC C+L G++N C SGQC C+ G QC+ Sbjct: 492 QCLPEHWGLS-----NDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPG 546 Query: 784 FY 785 +Y Sbjct: 547 YY 548 Score = 240 bits (613), Expect = 7e-63 Identities = 138/417 (33%), Positives = 194/417 (46%), Gaps = 46/417 (11%) Query: 641 CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSG 700 C+CD G+ S +CD GGQC C+ +V GR CN+C G + P GC PC C+ G Sbjct: 773 CECDPQGSL--SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCKPCECHLQG 827 Query: 701 TVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCEPCQCNLHGSVNK 757 +V+ C+ +GQC C V +CD C ++GF C+PCQCN H Sbjct: 828 SVNA--FCNPVTGQCHCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNGHADD-- 875 Query: 758 FCNPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT----NCKACDCDT---AGSLPGTVC- 808 C+P +G+C C+ G C+ C +YG + +C+ C C +G C Sbjct: 876 -CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCY 934 Query: 809 -NAKTGQ--CICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKST 865 + T Q C+C P G +C+ C G F C PC C C+K T Sbjct: 935 QDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKET 994 Query: 866 GQC-PCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI------CDPISG 918 G+C C G C C Y + Q C+ C C+ LGT+ CD +G Sbjct: 995 GRCLKCLYHTEGEHCQFCRFGYYGDALQ--QDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052 Query: 919 QCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIA 978 QCLC+PN G+ C++C P + + TGC PC+C+ + CN TGQC C Sbjct: 1053 QCLCLPNVIGQNCDRCAPNTW-QLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPG-FG 1110 Query: 979 GQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035 G+ C +C++ ++G DP C+ C+C G C TGQC C + V G +CD C Sbjct: 1111 GRTCSECQELFWG-DPDV-ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC 1165 Score = 202 bits (514), Expect = 2e-51 Identities = 162/562 (28%), Positives = 231/562 (41%), Gaps = 89/562 (15%) Query: 479 FVKATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQC------HGHADNCDTTS- 531 F K T YT+ + ++ Y +D + + C+ G D T S Sbjct: 672 FEKGTNYTVRLELPQYTSSDS-DVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSA 730 Query: 532 ----QPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYN 587 Q YRCL + S + D C + A C P S S C N Sbjct: 731 WETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQ--GSLSSVCDPN 788 Query: 588 ISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVG 647 GG C C N GR C C F G PS CKPC+C G Sbjct: 789 --------------GGQCQ-CRPNVVGRTCNRCAPGTF---GFGPSG---CKPCECHLQG 827 Query: 648 TRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDIT 707 + N C+ + GQC+C + V RQC++C G + C PC CN G D Sbjct: 828 SVNA--FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS-----CQPCQCN--GHADD--- 875 Query: 708 CHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFND--VG----CEPCQC------NLHGS 754 C +G+C C+ +G C+ C G+ + D +G C PC C + Sbjct: 876 CDPVTGECLNCQDYTMGHNCERCLAGY-----YGDPIIGSGDHCRPCPCPDGPDSGRQFA 930 Query: 755 VNKFCNPHSGQ--CECKKEAKGLQCDTCRENFYGLDVT---NCKACDC-DTAGSLPGTVC 808 + + +P + Q C C G +CD C ++G +C+ C C + + C Sbjct: 931 RSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEAC 990 Query: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNF--YLRQNNSFLCLPCNCDKTGTI----NGS-LL 860 + +TG+C+ C + EG C C G + L+Q+ C C C+ GT+ NGS Sbjct: 991 DKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQ 1046 Query: 861 CNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQC 920 C+K+TGQC C V G C++C P+ + L C C C++ + G C+ +GQC Sbjct: 1047 CDKATGQCLCLPNVIGQNCDRCAPNTWQLASGT--GCDPCNCNAAHSF-GPSCNEFTGQC 1103 Query: 921 LCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980 C+P GR C++CQ F+ P C C C G C+ TGQCVC + + G Sbjct: 1104 QCMPGFGGRTCSECQELFWGDPD--VECRACDCDPRGIETPQCDQSTGQCVCVEG-VEGP 1160 Query: 981 RCDQCKDHYFGFDPQTGRCQPC 1002 RCD+C Y G P C C Sbjct: 1161 RCDKCTRGYSGVFPDCTPCHQC 1182 Score = 172 bits (437), Expect = 2e-42 Identities = 100/315 (31%), Positives = 143/315 (45%), Gaps = 31/315 (9%) Query: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806 C+C+ GS++ C+P+ GQC+C+ G C+ C +G + CK C+C GS+ Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSV-NA 831 Query: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG 866 CN TGQC C V RQC++CL G++ C PC C+ C+ TG Sbjct: 832 FCNPVTGQCHCFQGVYARQCDRCLPGHWGFPS-----CQPCQCNGHADD-----CDPVTG 881 Query: 867 QC-PCKLGVTGLRCNQCEPHRY-NLTIDNFQHCQMCECDS---LGTLPGTIC--DPISGQ 919 +C C+ G C +C Y + I + HC+ C C G C DP++ Q Sbjct: 882 ECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQ 941 Query: 920 --CLCVPNRQGRRCNQCQPGFYISPGNATG-CLPCSCHTTGAVN--HICNSLTGQCVCQD 974 C+C P G RC+ C G++ +P G C PC CH C+ TG+C+ Sbjct: 942 LACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001 Query: 975 ASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCH-------LVTGQCFCKQFV 1027 G+ C C+ Y+G D C+ C C+ G + E C+ TGQC C V Sbjct: 1002 YHTEGEHCQFCRFGYYG-DALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNV 1060 Query: 1028 TGSKCDACVPSASHL 1042 G CD C P+ L Sbjct: 1061 IGQNCDRCAPNTWQL 1075 Score = 160 bits (404), Expect = 1e-38 Identities = 90/257 (35%), Positives = 122/257 (47%), Gaps = 30/257 (11%) Query: 713 GQCKCKANVIGLRCDHC-----NFGFKFLRSFNDVGCEPCQCNLHGSVNKFC-------- 759 G C C+ N GL C+ C + ++ N C+ C CN H F Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355 Query: 760 NPHSGQCE-CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAKT 812 N G C+ C+ G C+ C+ +Y D C+ C CD AGS +C++ T Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYT 415 Query: 813 --------GQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864 GQC CK NVEG C+ C EG + L + F C C C+ GTI G C+ Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSE 475 Query: 865 TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924 TG C CK VTG C+QC P + L+ D C+ C+CD G L + C SGQC C P Sbjct: 476 TGHCYCKRLVTGQHCDQCLPEHWGLSND-LDGCRPCDCDLGGALNNS-CFAESGQCSCRP 533 Query: 925 NRQGRRCNQCQPGFYIS 941 + GR+CN+ +PG+Y + Sbjct: 534 HMIGRQCNEVEPGYYFA 550 Score = 153 bits (387), Expect = 1e-36 Identities = 88/271 (32%), Positives = 134/271 (49%), Gaps = 43/271 (15%) Query: 658 IGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDG-----CSPCNCNTSGTVDGDITCH--- 709 + G C C+ + G C C + +++L +G C CNCN + I+CH Sbjct: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCN-----EHSISCHFDM 348 Query: 710 --------QNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVN 756 + G C C+ N +G C+ C F + D+ CE C C+ GS N Sbjct: 349 AVYLATGNVSGGVCDDCQHNTMGRNCEQCK-PFYYQHPERDIRDPNFCERCTCDPAGSQN 407 Query: 757 K-FCNPHS--------GQCECKKEAKGLQCDTCRENFYGL---DVTNCKACDCDTAGSLP 804 + C+ ++ GQC CK +G CD C+E FY L D CK+C C+ G++P Sbjct: 408 EGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIP 467 Query: 805 G-TVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK 863 G C+++TG C CK V G+ C++CL ++ L N+ C PC+CD G +N S C Sbjct: 468 GGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGL-SNDLDGCRPCDCDLGGALNNS--CFA 524 Query: 864 STGQCPCKLGVTGLRCNQCEPHRYNLTIDNF 894 +GQC C+ + G +CN+ EP Y T+D++ Sbjct: 525 ESGQCSCRPHMIGRQCNEVEPGYYFATLDHY 555 Score = 148 bits (374), Expect = 3e-35 Identities = 85/258 (32%), Positives = 121/258 (46%), Gaps = 41/258 (15%) Query: 813 GQCICKPNVEGRQCNKCLEGNFY-------LRQNNSFLCLPCNCDKTGTINGSLLC---- 861 G C+C+ N +G C C++ FY NS C CNC++ S+ C Sbjct: 296 GHCMCRHNTKGLNCELCMD--FYHDLPWRPAEGRNSNACKKCNCNEH-----SISCHFDM 348 Query: 862 -------NKSTGQCP-CKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPG 910 N S G C C+ G C QC+P Y I + C+ C CD G+ Sbjct: 349 AVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE 408 Query: 911 TICDP--------ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAV-- 959 ICD I+GQC C N +G C+ C+ GFY +S + GC C+C+ G + Sbjct: 409 GICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPG 468 Query: 960 NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG 1019 + C+S TG C C+ + GQ CDQC ++G C+PC+C L GALN +C +G Sbjct: 469 GNPCDSETGHCYCKRL-VTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESG 527 Query: 1020 QCFCKQFVTGSKCDACVP 1037 QC C+ + G +C+ P Sbjct: 528 QCSCRPHMIGRQCNEVEP 545 Score = 137 bits (344), Expect = 1e-31 Identities = 80/263 (30%), Positives = 123/263 (46%), Gaps = 46/263 (17%) Query: 764 GQCECKKEAKGLQCDTCRENFY--------GLDVTNCKACDCD--------------TAG 801 G C C+ KGL C+ C + ++ G + CK C+C+ G Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355 Query: 802 SLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ-----NNSFLCLPCNCDKTGTIN 856 ++ G VC+ C+ N GR C +C FY + + C C CD G+ N Sbjct: 356 NVSGGVCDD------CQHNTMGRNCEQCKP--FYYQHPERDIRDPNFCERCTCDPAGSQN 407 Query: 857 GSLLCNKST--------GQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908 + C+ T GQC CKL V G C+ C+ Y+L+ ++ C+ C C+ LGT+ Sbjct: 408 EGI-CDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTI 466 Query: 909 PG-TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLT 967 PG CD +G C C G+ C+QC P + + GC PC C GA+N+ C + + Sbjct: 467 PGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAES 526 Query: 968 GQCVCQDASIAGQRCDQCKDHYF 990 GQC C+ I G++C++ + Y+ Sbjct: 527 GQCSCRPHMI-GRQCNEVEPGYY 548 Score = 87.4 bits (215), Expect = 1e-16 Identities = 37/89 (41%), Positives = 54/89 (60%), Gaps = 3/89 (3%) Query: 949 LPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSG 1008 L C C G+++ +C+ GQC C+ ++ G+ C++C FGF P C+PC CHL G Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRP-NVVGRTCNRCAPGTFGFGPSG--CKPCECHLQG 827 Query: 1009 ALNETCHLVTGQCFCKQFVTGSKCDACVP 1037 ++N C+ VTGQC C Q V +CD C+P Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLP 856 Score = 69.7 bits (169), Expect = 2e-11 Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 29/163 (17%) Query: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC-------SCHTTGAVNHI 962 + G C+C N +G C C ++ P N+ C C SCH AV Sbjct: 294 VHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLA 353 Query: 963 CNSLTGQCVCQDA--SIAGQRCDQCKDHYFGFDPQTGR----CQPCNCHLSGALNE---- 1012 +++G VC D + G+ C+QCK Y+ + R C+ C C +G+ NE Sbjct: 354 TGNVSGG-VCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICD 412 Query: 1013 -----TCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 + L+ GQC CK V G CD C L + GC Sbjct: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGC 455 >gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo sapiens] Length = 3118 Score = 275 bits (704), Expect = 2e-73 Identities = 171/471 (36%), Positives = 229/471 (48%), Gaps = 52/471 (11%) Query: 604 VCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC- 662 VC C TG +CE C R G I C+PC C + CD + G+C Sbjct: 723 VCQ-CPPGYTGSSCESCWPRHRRVNGTIFGGI--CEPCQCF-----GHAESCDDVTGECL 774 Query: 663 NCKRHVSGRQCNQCQNGFYNLQELDP-DGCSPCNCNTSGTVDG-DITCHQNSGQ---CK- 716 NCK H G C++C GFY + C PC C + + TCH + C Sbjct: 775 NCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDG 834 Query: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN--LHGSVNKFCNPHSGQCE-CKKEAK 773 C G RC+ C G+ S C+PCQCN L S+ C+ SG C CK Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894 Query: 774 GLQCDTCRENFYG--LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831 G C+ C + ++G +D NC+ C C+ GS VC+++TGQC C+ NV+G++C+KC Sbjct: 895 GRYCELCADGYFGDAVDAKNCQPCRCNAGGSF-SEVCHSQTGQCECRANVQGQRCDKCKA 953 Query: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891 G F L+ C+PCNC+ G+ S C +S GQC C+ GVTG +C++C H Y Sbjct: 954 GTFGLQSARG--CVPCNCNSFGS--KSFDCEES-GQCWCQPGVTGKKCDRCA-HGYF--- 1004 Query: 892 DNFQH--CQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCL 949 NFQ C CEC LG CDP +G+C+C PN G +C++C P + TGC Sbjct: 1005 -NFQEGGCTACECSHLGNN----CDPKTGRCICPPNTIGEKCSKCAPNTW-GHSITTGCK 1058 Query: 950 PCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGA 1009 C+C T G+++ CN TGQC C +G +C +C ++ + RC C+C L G Sbjct: 1059 ACNCSTVGSLDFQCNVNTGQCNCHP-KFSGAKCTECSRGHWNYP----RCNLCDCFLPGT 1113 Query: 1010 LNETCHLVT---------GQCFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051 TC T GQC CK V G CD C P LD N LGCS Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCS 1164 Score = 273 bits (699), Expect = 7e-73 Identities = 154/456 (33%), Positives = 218/456 (47%), Gaps = 58/456 (12%) Query: 518 CQCHGHADNC-DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQ 576 CQC GHA++C D T + C + T G +CD+CLP + +P + + +C+PC Sbjct: 757 CQCFGHAESCDDVTGECLNC----KDHTGGPYCDKCLPGFYGEPTKGTSE----DCQPCA 808 Query: 577 C------NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630 C N+ S +CH + S+ G +CD C TG CE C + +F Q Sbjct: 809 CPLNIPSNNFSPTCHLDRSL-----------GLICDGCPVGYTGPRCERCAEGYFGQPSV 857 Query: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPD 689 + C+PC C+ + CD + G C CK +GR C C +G++ +D Sbjct: 858 PGGS---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFG-DAVDAK 913 Query: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749 C PC CN G+ CH +GQC+C+ANV G RCD C G L+S GC PC C Sbjct: 914 NCQPCRCNAGGSFSE--VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSAR--GCVPCNC 969 Query: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809 N GS + C SGQC C+ G +CD C ++ C AC+C S G C+ Sbjct: 970 NSFGSKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC----SHLGNNCD 1024 Query: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP 869 KTG+CIC PN G +C+KC + + + C CNC G+++ CN +TGQC Sbjct: 1025 PKTGRCICPPNTIGEKCSKCAPNTW--GHSITTGCKACNCSTVGSLD--FQCNVNTGQCN 1080 Query: 870 CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI--------CDPISGQCL 921 C +G +C +C + N+ C +C+C GT T C +GQC Sbjct: 1081 CHPKFSGAKCTECSRGHW-----NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT 1135 Query: 922 CVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTT 956 C N +G C++C+PG F + N GC C C T Sbjct: 1136 CKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGT 1171 Score = 235 bits (600), Expect = 2e-61 Identities = 138/475 (29%), Positives = 216/475 (45%), Gaps = 54/475 (11%) Query: 546 GLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVC 605 G C+ C P + R ++ C+PCQC H++SC G C Sbjct: 732 GSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD--------------DVTGEC 773 Query: 606 DDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCD-TVGTRNGSILCD---QIGGQ 661 +C+ +T G C+ C F+ + S + C+PC C + + N S C +G Sbjct: 774 LNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCACPLNIPSNNFSPTCHLDRSLGLI 831 Query: 662 CN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK-CKA 719 C+ C +G +C +C G++ + C PC CN + +C SG C CK Sbjct: 832 CDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP 891 Query: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779 G C+ C G+ F + + C+PC+CN GS ++ C+ +GQCEC+ +G +CD Sbjct: 892 GTTGRYCELCADGY-FGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK 950 Query: 780 CRENFYGL-DVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ 838 C+ +GL C C+C++ GS C ++GQC C+P V G++C++C G F ++ Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGS-KSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQE 1008 Query: 839 NNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQ 898 C C C G C+ TG+C C G +C++C P+ + +I C+ Sbjct: 1009 GG---CTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCK 1058 Query: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGA 958 C C ++G+L C+ +GQC C P G +C +C G + N C C C G Sbjct: 1059 ACNCSTVGSLDFQ-CNVNTGQCNCHPKFSGAKCTECSRGHW----NYPRCNLCDCFLPGT 1113 Query: 959 VNHICNSLTGQCVCQD--------ASIAGQRCDQCKDHYFGFDPQTG-RCQPCNC 1004 C+S T +C C D ++ G CD+C+ FG D + C C C Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC 1168 Score = 194 bits (492), Expect = 7e-49 Identities = 138/449 (30%), Positives = 205/449 (45%), Gaps = 53/449 (11%) Query: 336 NP-EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQ 393 NP + HP++ D T W S N + + VTI++DL+ +Q+ Y+I++ SP+ Sbjct: 92 NPNQRHPITNAIDGK-NTWWQSPSIKNGIEYHY-VTITLDLQQ-VFQIAYVIVKAANSPR 148 Query: 394 PTEIRIQRKKENSLDWEDWQYFA---RNC----GAFGMKNNGDLEKPDSVNCLQL-SNFT 445 P ++R ++ ++++ WQY A C + K D V C S Sbjct: 149 PGNWILERSLDD-VEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIH 207 Query: 446 PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR 505 P G + S++ N RP ++ +P L EF A IR F + H+ Sbjct: 208 PLENGEIHISLI----NGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFAHK 261 Query: 506 -------------YYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRC 552 YY+V +I++ G C C+GHA C + C E T G CD+C Sbjct: 262 DPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQC 321 Query: 553 LPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDC 608 P ++ KP+R G + C+ C C+ ++ C+Y+ +V + RG GGGVC +C Sbjct: 322 CPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381 Query: 609 EHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ-------IGGQ 661 NT G NCE C D FFR G P+ C+PC CD +G+ N + D+ G Sbjct: 382 TQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGS 441 Query: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721 C+CK G C++C G+ PD C CNC+ G+ + D C G C CK NV Sbjct: 442 CHCKTGFGGVSCDRCARGYTGY----PD-CKACNCSGLGSKNED-PCF---GPCICKENV 492 Query: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750 G C C GF L+ N GC+ C C+ Sbjct: 493 EGGDCSRCKSGFFNLQEDNWKGCDECFCS 521 Score = 124 bits (312), Expect = 5e-28 Identities = 86/289 (29%), Positives = 122/289 (42%), Gaps = 39/289 (13%) Query: 785 YGLD-VTNCKACDCDTAGSLP--GTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNS 841 +G+D + + + ++A S P G++ A C C P G C C + R N + Sbjct: 692 FGMDAIFRLSSVNLESAVSYPTDGSIA-AAVEVCQCPPGYTGSSCESCWPR--HRRVNGT 748 Query: 842 F---LCLPCNCDKTGTINGSLLCNKSTGQC-PCKLGVTGLRCNQCEPHRYNL-TIDNFQH 896 +C PC C + C+ TG+C CK G C++C P Y T + Sbjct: 749 IFGGICEPCQC-----FGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED 803 Query: 897 CQMCECD------------SLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGN 944 CQ C C L G ICD C G RC +C G++ P Sbjct: 804 CQPCACPLNIPSNNFSPTCHLDRSLGLICDG------CPVGYTGPRCERCAEGYFGQPSV 857 Query: 945 ATG-CLPCSCHTT--GAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQP 1001 G C PC C+ ++ C+SL+G C+ G+ C+ C D YFG CQP Sbjct: 858 PGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQP 917 Query: 1002 CNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 C C+ G+ +E CH TGQC C+ V G +CD C A + + GC Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC--KAGTFGLQSARGC 964 Score = 106 bits (264), Expect = 2e-22 Identities = 70/223 (31%), Positives = 94/223 (42%), Gaps = 42/223 (18%) Query: 661 QCNCKRHVSGRQCNQCQNGFYNLQE-----LDPDGCSPCNC----------------NTS 699 +C C+ + G C+QC GF+ L C CNC N S Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365 Query: 700 GTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGF---KFLRSFNDVGCEPCQCNLHGSV 755 + G + G C C N G+ C+ C GF K + C+PC C+ GS+ Sbjct: 366 LNIRGK---YIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSL 422 Query: 756 NKFC---NPHS------GQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806 N+ C H+ G C CK G+ CD C + G +CKAC+C GS Sbjct: 423 NEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP--DCKACNCSGLGSKNED 480 Query: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849 C G CICK NVEG C++C G F L+++N C C C Sbjct: 481 PC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520 Score = 94.0 bits (232), Expect = 1e-18 Identities = 70/251 (27%), Positives = 102/251 (40%), Gaps = 51/251 (20%) Query: 749 CNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG--------LDVTNCKACDC--- 797 C L + NK +CEC+ G CD C F+ L T C+AC+C Sbjct: 296 CPLDPATNK------SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGK 349 Query: 798 ------DTAGSLPGTVCNAKT-----GQCI-CKPNVEGRQCNKCLEGNFY---LRQNNSF 842 D + N + G CI C N G C C +G F + N Sbjct: 350 AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPR 409 Query: 843 LCLPCNCDKTGTINGSLLCNK-------STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895 C PC+CD G++N + ++ + G C CK G G+ C++C + Sbjct: 410 PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG-----YTGYP 464 Query: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCH 954 C+ C C LG+ DP G C+C N +G C++C+ GF+ + N GC C C Sbjct: 465 DCKACNCSGLGSKNE---DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC- 520 Query: 955 TTGAVNHICNS 965 V++ C S Sbjct: 521 --SGVSNRCQS 529 Score = 92.0 bits (227), Expect = 4e-18 Identities = 58/186 (31%), Positives = 75/186 (40%), Gaps = 21/186 (11%) Query: 867 QCPCKLGVTGLRCNQCEPHRYNLTID--------NFQHCQMCECDSLGTLPGTICDPISG 918 +C C LG +GL C C P Y L C C+C+ +L CDP + Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL----CDPETS 1434 Query: 919 QCL-CVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQ------C 970 C C + G C +C G+Y I G C C+C + N+ S + C Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRC 1494 Query: 971 VCQDASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNETCHLVTGQCFCKQFVTG 1029 GQ C++C Y G G CQ C C G+L C VTG C C+ TG Sbjct: 1495 TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATG 1554 Query: 1030 SKCDAC 1035 KCD C Sbjct: 1555 RKCDGC 1560 Score = 91.7 bits (226), Expect = 5e-18 Identities = 60/219 (27%), Positives = 90/219 (41%), Gaps = 31/219 (14%) Query: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG---------CSPCNCNTSGTVDGDITCHQN 711 +C+C SG C C GFY L+ P G C PC CN ++ C Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRS-QPGGRTPGPTLGTCVPCQCNGHSSL-----CDPE 1432 Query: 712 SGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ----- 765 + C+ C+ + G C+ C G+ + C+ C C L S N F + Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492 Query: 766 --CECKKEAKGLQCDTCRENFYGLDVT---NCKACDCDTAGSLPGTVCNAKTGQCICKPN 820 C + +G C+ C + G +C+ C+CD GSLP C+ TG C C+P Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP-VPCDPVTGFCTCRPG 1551 Query: 821 VEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSL 859 GR+C+ C + + C+ C + TG + G L Sbjct: 1552 ATGRKCDGCK----HWHAREGWECVFCGDECTGLLLGDL 1586 Score = 91.3 bits (225), Expect = 7e-18 Identities = 64/234 (27%), Positives = 99/234 (42%), Gaps = 31/234 (13%) Query: 607 DCEHNTTGRNCELCKDYFFR----QVGADPS-AIDVCKPCDCDTVGTRNGSILCDQIGGQ 661 DC +G +CE C F+R G P + C PC C+ S LCD Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-----GHSSLCDPETSI 1435 Query: 662 C-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC---------NTSGTVDG--DITCH 709 C NC+ H +G C +C G+Y + + P+ C C C + S +G D C Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRC- 1494 Query: 710 QNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK 769 C G C+ C G+ C+ C+C+ +GS+ C+P +G C C+ Sbjct: 1495 -----TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549 Query: 770 KEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEG 823 A G +CD C+ +++ + C C + G L G + A+ Q + N+ G Sbjct: 1550 PGATGRKCDGCK-HWHAREGWECVFCGDECTGLLLGDL--ARLEQMVMSINLTG 1600 Score = 85.1 bits (209), Expect = 5e-16 Identities = 64/231 (27%), Positives = 91/231 (39%), Gaps = 46/231 (19%) Query: 711 NSGQCKCKANVIGLRCDHCNFGF--KFLRSFNDVGCEPCQ-CNLHGSVNKFCNPHS---- 763 N +C+C+ N G CD C GF K R+ + C+ CN HG + + Sbjct: 303 NKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARR 362 Query: 764 -------------GQC-ECKKEAKGLQCDTCRENFYGLDVTN------CKACDCDTAGSL 803 G C C + G+ C+TC + F+ + C+ C CD GSL Sbjct: 363 NLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSL 422 Query: 804 PGTVC---------NAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGT 854 VC G C CK G C++C G Y + C CNC G+ Sbjct: 423 -NEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG--YTGYPD---CKACNCSGLGS 476 Query: 855 INGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSL 905 N + G C CK V G C++C+ +NL DN++ C C C + Sbjct: 477 KNE----DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGV 523 Score = 84.3 bits (207), Expect = 8e-16 Identities = 54/188 (28%), Positives = 78/188 (41%), Gaps = 22/188 (11%) Query: 765 QCECKKEAKGLQCDTCRENFY-----------GLDVTNCKACDCDTAGSLPGTVCNAKTG 813 +C+C GL C+ C FY G + C C C+ SL C+ +T Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL----CDPETS 1434 Query: 814 QCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG----QC 868 C C+ + G C +C G + + + C C C + N + G +C Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRC 1494 Query: 869 P-CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQ 927 C G G C +C P + CQ CECD G+LP CDP++G C C P Sbjct: 1495 TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP-VPCDPVTGFCTCRPGAT 1553 Query: 928 GRRCNQCQ 935 GR+C+ C+ Sbjct: 1554 GRKCDGCK 1561 Score = 82.4 bits (202), Expect = 3e-15 Identities = 53/192 (27%), Positives = 78/192 (40%), Gaps = 27/192 (14%) Query: 546 GLHCDRCLPLY---NDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGG 602 GL C+ CLP + +P + C PCQCN HS C S Sbjct: 1388 GLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETS------------- 1434 Query: 603 GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNG-SILCDQIG-- 659 +C +C+H+T G CE C ++ V P+ C+ C C + + N S C G Sbjct: 1435 -ICQNCQHHTAGDFCERCALGYYGIVKGLPND---CQQCACPLISSSNNFSPSCVAEGLD 1490 Query: 660 -GQCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKC 717 +C C R G+ C +C G+ C C C+ G++ + C +G C C Sbjct: 1491 DYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL--PVPCDPVTGFCTC 1548 Query: 718 KANVIGLRCDHC 729 + G +CD C Sbjct: 1549 RPGATGRKCDGC 1560 Score = 82.0 bits (201), Expect = 4e-15 Identities = 63/227 (27%), Positives = 84/227 (37%), Gaps = 48/227 (21%) Query: 862 NKSTGQCPCKLGVTGLRCNQCEP--HRYNLTIDNF---QHCQMCECDSLG---------- 906 NKS +C C+ G C+QC P H+ F C+ C C Sbjct: 303 NKS--RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA 360 Query: 907 ------TLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFY----ISPGNATGCLPCSCHT 955 + G G C+ C N G C C GF+ +SP C PC C Sbjct: 361 RRNLSLNIRGKYIG--GGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDP 418 Query: 956 TGAVNHIC---------NSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006 G++N +C G C C+ G CD+C Y G+ C+ CNC Sbjct: 419 IGSLNEVCVKDEKHARRGLAPGSCHCK-TGFGGVSCDRCARGYTGYPD----CKACNCSG 473 Query: 1007 SGALNET-CHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052 G+ NE C G C CK+ V G C C +L +N GC + Sbjct: 474 LGSKNEDPCF---GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDE 517 Score = 67.0 bits (162), Expect = 1e-10 Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 22/163 (13%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQ-ESFTEGLHCDRC-LPLYNDKPFRQGDQVYAFNCKPC 575 CQC+GH+ CD P +C + T G C+RC L Y D C+ C Sbjct: 1420 CQCNGHSSLCD----PETSICQNCQHHTAGDFCERCALGYYGIVKGLPND------CQQC 1469 Query: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635 C S S +++ S + +R C C G+ CE C + G+ + Sbjct: 1470 ACPLISSSNNFSPSCVAEGLDDYR-----CTACPRGYEGQYCERCAPGY---TGSPGNPG 1521 Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQN 678 C+ C+CD G+ + CD + G C C+ +GR+C+ C++ Sbjct: 1522 GSCQECECDPYGSL--PVPCDPVTGFCTCRPGATGRKCDGCKH 1562 Score = 44.3 bits (103), Expect = 0.001 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 18/94 (19%) Query: 534 YRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPF 593 YRC + EG +C+RC P Y P G +C+ C+C+ + + DP Sbjct: 1492 YRCTACPRGY-EGQYCERCAPGYTGSPGNPGG-----SCQECECDPYGS---LPVPCDPV 1542 Query: 594 PFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627 G C C TGR C+ CK + R+ Sbjct: 1543 T--------GFC-TCRPGATGRKCDGCKHWHARE 1567 >gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sapiens] Length = 3122 Score = 275 bits (704), Expect = 2e-73 Identities = 171/471 (36%), Positives = 229/471 (48%), Gaps = 52/471 (11%) Query: 604 VCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC- 662 VC C TG +CE C R G I C+PC C + CD + G+C Sbjct: 723 VCQ-CPPGYTGSSCESCWPRHRRVNGTIFGGI--CEPCQCF-----GHAESCDDVTGECL 774 Query: 663 NCKRHVSGRQCNQCQNGFYNLQELDP-DGCSPCNCNTSGTVDG-DITCHQNSGQ---CK- 716 NCK H G C++C GFY + C PC C + + TCH + C Sbjct: 775 NCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDG 834 Query: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN--LHGSVNKFCNPHSGQCE-CKKEAK 773 C G RC+ C G+ S C+PCQCN L S+ C+ SG C CK Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894 Query: 774 GLQCDTCRENFYG--LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831 G C+ C + ++G +D NC+ C C+ GS VC+++TGQC C+ NV+G++C+KC Sbjct: 895 GRYCELCADGYFGDAVDAKNCQPCRCNAGGSF-SEVCHSQTGQCECRANVQGQRCDKCKA 953 Query: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTI 891 G F L+ C+PCNC+ G+ S C +S GQC C+ GVTG +C++C H Y Sbjct: 954 GTFGLQSARG--CVPCNCNSFGS--KSFDCEES-GQCWCQPGVTGKKCDRCA-HGYF--- 1004 Query: 892 DNFQH--CQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCL 949 NFQ C CEC LG CDP +G+C+C PN G +C++C P + TGC Sbjct: 1005 -NFQEGGCTACECSHLGNN----CDPKTGRCICPPNTIGEKCSKCAPNTW-GHSITTGCK 1058 Query: 950 PCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGA 1009 C+C T G+++ CN TGQC C +G +C +C ++ + RC C+C L G Sbjct: 1059 ACNCSTVGSLDFQCNVNTGQCNCHP-KFSGAKCTECSRGHWNYP----RCNLCDCFLPGT 1113 Query: 1010 LNETCHLVT---------GQCFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051 TC T GQC CK V G CD C P LD N LGCS Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCS 1164 Score = 273 bits (699), Expect = 7e-73 Identities = 154/456 (33%), Positives = 218/456 (47%), Gaps = 58/456 (12%) Query: 518 CQCHGHADNC-DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQ 576 CQC GHA++C D T + C + T G +CD+CLP + +P + + +C+PC Sbjct: 757 CQCFGHAESCDDVTGECLNC----KDHTGGPYCDKCLPGFYGEPTKGTSE----DCQPCA 808 Query: 577 C------NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630 C N+ S +CH + S+ G +CD C TG CE C + +F Q Sbjct: 809 CPLNIPSNNFSPTCHLDRSL-----------GLICDGCPVGYTGPRCERCAEGYFGQPSV 857 Query: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPD 689 + C+PC C+ + CD + G C CK +GR C C +G++ +D Sbjct: 858 PGGS---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFG-DAVDAK 913 Query: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749 C PC CN G+ CH +GQC+C+ANV G RCD C G L+S GC PC C Sbjct: 914 NCQPCRCNAGGSFSE--VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSAR--GCVPCNC 969 Query: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCN 809 N GS + C SGQC C+ G +CD C ++ C AC+C S G C+ Sbjct: 970 NSFGSKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC----SHLGNNCD 1024 Query: 810 AKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP 869 KTG+CIC PN G +C+KC + + + C CNC G+++ CN +TGQC Sbjct: 1025 PKTGRCICPPNTIGEKCSKCAPNTW--GHSITTGCKACNCSTVGSLD--FQCNVNTGQCN 1080 Query: 870 CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI--------CDPISGQCL 921 C +G +C +C + N+ C +C+C GT T C +GQC Sbjct: 1081 CHPKFSGAKCTECSRGHW-----NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT 1135 Query: 922 CVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTT 956 C N +G C++C+PG F + N GC C C T Sbjct: 1136 CKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGT 1171 Score = 235 bits (600), Expect = 2e-61 Identities = 138/475 (29%), Positives = 216/475 (45%), Gaps = 54/475 (11%) Query: 546 GLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVC 605 G C+ C P + R ++ C+PCQC H++SC G C Sbjct: 732 GSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD--------------DVTGEC 773 Query: 606 DDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCD-TVGTRNGSILCD---QIGGQ 661 +C+ +T G C+ C F+ + S + C+PC C + + N S C +G Sbjct: 774 LNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCACPLNIPSNNFSPTCHLDRSLGLI 831 Query: 662 CN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK-CKA 719 C+ C +G +C +C G++ + C PC CN + +C SG C CK Sbjct: 832 CDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP 891 Query: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779 G C+ C G+ F + + C+PC+CN GS ++ C+ +GQCEC+ +G +CD Sbjct: 892 GTTGRYCELCADGY-FGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK 950 Query: 780 CRENFYGL-DVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ 838 C+ +GL C C+C++ GS C ++GQC C+P V G++C++C G F ++ Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGS-KSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQE 1008 Query: 839 NNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQ 898 C C C G C+ TG+C C G +C++C P+ + +I C+ Sbjct: 1009 GG---CTACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCK 1058 Query: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGA 958 C C ++G+L C+ +GQC C P G +C +C G + N C C C G Sbjct: 1059 ACNCSTVGSLDFQ-CNVNTGQCNCHPKFSGAKCTECSRGHW----NYPRCNLCDCFLPGT 1113 Query: 959 VNHICNSLTGQCVCQD--------ASIAGQRCDQCKDHYFGFDPQTG-RCQPCNC 1004 C+S T +C C D ++ G CD+C+ FG D + C C C Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC 1168 Score = 194 bits (492), Expect = 7e-49 Identities = 138/449 (30%), Positives = 205/449 (45%), Gaps = 53/449 (11%) Query: 336 NP-EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFF-SPQ 393 NP + HP++ D T W S N + + VTI++DL+ +Q+ Y+I++ SP+ Sbjct: 92 NPNQRHPITNAIDGK-NTWWQSPSIKNGIEYHY-VTITLDLQQ-VFQIAYVIVKAANSPR 148 Query: 394 PTEIRIQRKKENSLDWEDWQYFA---RNC----GAFGMKNNGDLEKPDSVNCLQL-SNFT 445 P ++R ++ ++++ WQY A C + K D V C S Sbjct: 149 PGNWILERSLDD-VEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIH 207 Query: 446 PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR 505 P G + S++ N RP ++ +P L EF A IR F + H+ Sbjct: 208 PLENGEIHISLI----NGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFAHK 261 Query: 506 -------------YYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRC 552 YY+V +I++ G C C+GHA C + C E T G CD+C Sbjct: 262 DPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQC 321 Query: 553 LPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-HFRG---GGGVCDDC 608 P ++ KP+R G + C+ C C+ ++ C+Y+ +V + RG GGGVC +C Sbjct: 322 CPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381 Query: 609 EHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ-------IGGQ 661 NT G NCE C D FFR G P+ C+PC CD +G+ N + D+ G Sbjct: 382 TQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGS 441 Query: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721 C+CK G C++C G+ PD C CNC+ G+ + D C G C CK NV Sbjct: 442 CHCKTGFGGVSCDRCARGYTGY----PD-CKACNCSGLGSKNED-PCF---GPCICKENV 492 Query: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750 G C C GF L+ N GC+ C C+ Sbjct: 493 EGGDCSRCKSGFFNLQEDNWKGCDECFCS 521 Score = 124 bits (312), Expect = 5e-28 Identities = 86/289 (29%), Positives = 122/289 (42%), Gaps = 39/289 (13%) Query: 785 YGLD-VTNCKACDCDTAGSLP--GTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNS 841 +G+D + + + ++A S P G++ A C C P G C C + R N + Sbjct: 692 FGMDAIFRLSSVNLESAVSYPTDGSIA-AAVEVCQCPPGYTGSSCESCWPR--HRRVNGT 748 Query: 842 F---LCLPCNCDKTGTINGSLLCNKSTGQC-PCKLGVTGLRCNQCEPHRYNL-TIDNFQH 896 +C PC C + C+ TG+C CK G C++C P Y T + Sbjct: 749 IFGGICEPCQC-----FGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED 803 Query: 897 CQMCECD------------SLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGN 944 CQ C C L G ICD C G RC +C G++ P Sbjct: 804 CQPCACPLNIPSNNFSPTCHLDRSLGLICDG------CPVGYTGPRCERCAEGYFGQPSV 857 Query: 945 ATG-CLPCSCHTT--GAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQP 1001 G C PC C+ ++ C+SL+G C+ G+ C+ C D YFG CQP Sbjct: 858 PGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQP 917 Query: 1002 CNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 C C+ G+ +E CH TGQC C+ V G +CD C A + + GC Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC--KAGTFGLQSARGC 964 Score = 106 bits (264), Expect = 2e-22 Identities = 70/223 (31%), Positives = 94/223 (42%), Gaps = 42/223 (18%) Query: 661 QCNCKRHVSGRQCNQCQNGFYNLQE-----LDPDGCSPCNC----------------NTS 699 +C C+ + G C+QC GF+ L C CNC N S Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365 Query: 700 GTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGF---KFLRSFNDVGCEPCQCNLHGSV 755 + G + G C C N G+ C+ C GF K + C+PC C+ GS+ Sbjct: 366 LNIRGK---YIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSL 422 Query: 756 NKFC---NPHS------GQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806 N+ C H+ G C CK G+ CD C + G +CKAC+C GS Sbjct: 423 NEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP--DCKACNCSGLGSKNED 480 Query: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849 C G CICK NVEG C++C G F L+++N C C C Sbjct: 481 PC---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520 Score = 94.0 bits (232), Expect = 1e-18 Identities = 70/251 (27%), Positives = 102/251 (40%), Gaps = 51/251 (20%) Query: 749 CNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG--------LDVTNCKACDC--- 797 C L + NK +CEC+ G CD C F+ L T C+AC+C Sbjct: 296 CPLDPATNK------SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGK 349 Query: 798 ------DTAGSLPGTVCNAKT-----GQCI-CKPNVEGRQCNKCLEGNFY---LRQNNSF 842 D + N + G CI C N G C C +G F + N Sbjct: 350 AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPR 409 Query: 843 LCLPCNCDKTGTINGSLLCNK-------STGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895 C PC+CD G++N + ++ + G C CK G G+ C++C + Sbjct: 410 PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG-----YTGYP 464 Query: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCH 954 C+ C C LG+ DP G C+C N +G C++C+ GF+ + N GC C C Sbjct: 465 DCKACNCSGLGSKNE---DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC- 520 Query: 955 TTGAVNHICNS 965 V++ C S Sbjct: 521 --SGVSNRCQS 529 Score = 92.0 bits (227), Expect = 4e-18 Identities = 58/186 (31%), Positives = 75/186 (40%), Gaps = 21/186 (11%) Query: 867 QCPCKLGVTGLRCNQCEPHRYNLTID--------NFQHCQMCECDSLGTLPGTICDPISG 918 +C C LG +GL C C P Y L C C+C+ +L CDP + Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL----CDPETS 1434 Query: 919 QCL-CVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQ------C 970 C C + G C +C G+Y I G C C+C + N+ S + C Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRC 1494 Query: 971 VCQDASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNETCHLVTGQCFCKQFVTG 1029 GQ C++C Y G G CQ C C G+L C VTG C C+ TG Sbjct: 1495 TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATG 1554 Query: 1030 SKCDAC 1035 KCD C Sbjct: 1555 RKCDGC 1560 Score = 91.7 bits (226), Expect = 5e-18 Identities = 60/219 (27%), Positives = 90/219 (41%), Gaps = 31/219 (14%) Query: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDPDG---------CSPCNCNTSGTVDGDITCHQN 711 +C+C SG C C GFY L+ P G C PC CN ++ C Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRS-QPGGRTPGPTLGTCVPCQCNGHSSL-----CDPE 1432 Query: 712 SGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ----- 765 + C+ C+ + G C+ C G+ + C+ C C L S N F + Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492 Query: 766 --CECKKEAKGLQCDTCRENFYGLDVT---NCKACDCDTAGSLPGTVCNAKTGQCICKPN 820 C + +G C+ C + G +C+ C+CD GSLP C+ TG C C+P Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP-VPCDPVTGFCTCRPG 1551 Query: 821 VEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSL 859 GR+C+ C + + C+ C + TG + G L Sbjct: 1552 ATGRKCDGCK----HWHAREGWECVFCGDECTGLLLGDL 1586 Score = 91.3 bits (225), Expect = 7e-18 Identities = 64/234 (27%), Positives = 99/234 (42%), Gaps = 31/234 (13%) Query: 607 DCEHNTTGRNCELCKDYFFR----QVGADPS-AIDVCKPCDCDTVGTRNGSILCDQIGGQ 661 DC +G +CE C F+R G P + C PC C+ S LCD Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN-----GHSSLCDPETSI 1435 Query: 662 C-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC---------NTSGTVDG--DITCH 709 C NC+ H +G C +C G+Y + + P+ C C C + S +G D C Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRC- 1494 Query: 710 QNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK 769 C G C+ C G+ C+ C+C+ +GS+ C+P +G C C+ Sbjct: 1495 -----TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549 Query: 770 KEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEG 823 A G +CD C+ +++ + C C + G L G + A+ Q + N+ G Sbjct: 1550 PGATGRKCDGCK-HWHAREGWECVFCGDECTGLLLGDL--ARLEQMVMSINLTG 1600 Score = 85.1 bits (209), Expect = 5e-16 Identities = 64/231 (27%), Positives = 91/231 (39%), Gaps = 46/231 (19%) Query: 711 NSGQCKCKANVIGLRCDHCNFGF--KFLRSFNDVGCEPCQ-CNLHGSVNKFCNPHS---- 763 N +C+C+ N G CD C GF K R+ + C+ CN HG + + Sbjct: 303 NKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARR 362 Query: 764 -------------GQC-ECKKEAKGLQCDTCRENFYGLDVTN------CKACDCDTAGSL 803 G C C + G+ C+TC + F+ + C+ C CD GSL Sbjct: 363 NLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSL 422 Query: 804 PGTVC---------NAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGT 854 VC G C CK G C++C G Y + C CNC G+ Sbjct: 423 -NEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG--YTGYPD---CKACNCSGLGS 476 Query: 855 INGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSL 905 N + G C CK V G C++C+ +NL DN++ C C C + Sbjct: 477 KNE----DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGV 523 Score = 84.3 bits (207), Expect = 8e-16 Identities = 54/188 (28%), Positives = 78/188 (41%), Gaps = 22/188 (11%) Query: 765 QCECKKEAKGLQCDTCRENFY-----------GLDVTNCKACDCDTAGSLPGTVCNAKTG 813 +C+C GL C+ C FY G + C C C+ SL C+ +T Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL----CDPETS 1434 Query: 814 QCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG----QC 868 C C+ + G C +C G + + + C C C + N + G +C Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRC 1494 Query: 869 P-CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQ 927 C G G C +C P + CQ CECD G+LP CDP++G C C P Sbjct: 1495 TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP-VPCDPVTGFCTCRPGAT 1553 Query: 928 GRRCNQCQ 935 GR+C+ C+ Sbjct: 1554 GRKCDGCK 1561 Score = 82.4 bits (202), Expect = 3e-15 Identities = 53/192 (27%), Positives = 78/192 (40%), Gaps = 27/192 (14%) Query: 546 GLHCDRCLPLY---NDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGG 602 GL C+ CLP + +P + C PCQCN HS C S Sbjct: 1388 GLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETS------------- 1434 Query: 603 GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNG-SILCDQIG-- 659 +C +C+H+T G CE C ++ V P+ C+ C C + + N S C G Sbjct: 1435 -ICQNCQHHTAGDFCERCALGYYGIVKGLPND---CQQCACPLISSSNNFSPSCVAEGLD 1490 Query: 660 -GQCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKC 717 +C C R G+ C +C G+ C C C+ G++ + C +G C C Sbjct: 1491 DYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL--PVPCDPVTGFCTC 1548 Query: 718 KANVIGLRCDHC 729 + G +CD C Sbjct: 1549 RPGATGRKCDGC 1560 Score = 82.0 bits (201), Expect = 4e-15 Identities = 63/227 (27%), Positives = 84/227 (37%), Gaps = 48/227 (21%) Query: 862 NKSTGQCPCKLGVTGLRCNQCEP--HRYNLTIDNF---QHCQMCECDSLG---------- 906 NKS +C C+ G C+QC P H+ F C+ C C Sbjct: 303 NKS--RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA 360 Query: 907 ------TLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFY----ISPGNATGCLPCSCHT 955 + G G C+ C N G C C GF+ +SP C PC C Sbjct: 361 RRNLSLNIRGKYIG--GGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDP 418 Query: 956 TGAVNHIC---------NSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006 G++N +C G C C+ G CD+C Y G+ C+ CNC Sbjct: 419 IGSLNEVCVKDEKHARRGLAPGSCHCK-TGFGGVSCDRCARGYTGYPD----CKACNCSG 473 Query: 1007 SGALNET-CHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052 G+ NE C G C CK+ V G C C +L +N GC + Sbjct: 474 LGSKNEDPCF---GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDE 517 Score = 67.0 bits (162), Expect = 1e-10 Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 22/163 (13%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQ-ESFTEGLHCDRC-LPLYNDKPFRQGDQVYAFNCKPC 575 CQC+GH+ CD P +C + T G C+RC L Y D C+ C Sbjct: 1420 CQCNGHSSLCD----PETSICQNCQHHTAGDFCERCALGYYGIVKGLPND------CQQC 1469 Query: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635 C S S +++ S + +R C C G+ CE C + G+ + Sbjct: 1470 ACPLISSSNNFSPSCVAEGLDDYR-----CTACPRGYEGQYCERCAPGY---TGSPGNPG 1521 Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQN 678 C+ C+CD G+ + CD + G C C+ +GR+C+ C++ Sbjct: 1522 GSCQECECDPYGSL--PVPCDPVTGFCTCRPGATGRKCDGCKH 1562 Score = 44.3 bits (103), Expect = 0.001 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 18/94 (19%) Query: 534 YRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPF 593 YRC + EG +C+RC P Y P G +C+ C+C+ + + DP Sbjct: 1492 YRCTACPRGY-EGQYCERCAPGYTGSPGNPGG-----SCQECECDPYGS---LPVPCDPV 1542 Query: 594 PFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627 G C C TGR C+ CK + R+ Sbjct: 1543 T--------GFC-TCRPGATGRKCDGCKHWHARE 1567 >gi|119703755 laminin, beta 2 precursor [Homo sapiens] Length = 1798 Score = 271 bits (694), Expect = 3e-72 Identities = 169/539 (31%), Positives = 260/539 (48%), Gaps = 72/539 (13%) Query: 290 SGDLL-----RLHAQSHCRCPGSHPRVHPLAQRYCIPNDAGDT-----ADNR---VSRLN 336 +GDLL RL A S C G P YCI + D D+R +R N Sbjct: 51 TGDLLVGRADRLTASSTCGLNGPQP--------YCIVSHLQDEKKCFLCDSRRPFSARDN 102 Query: 337 PEAHPLSFVNDNDVGTSWVSNVFTNITQLNQG---VTISVDLENGQYQVFYIIIQFFSPQ 393 P +H + +V TS+ Q G VTI +DLE ++ ++I+ F + + Sbjct: 103 PHSHRIQ-----NVVTSFAPQRRAAWWQSENGIPAVTIQLDLE-AEFHFTHLIMTFKTFR 156 Query: 394 PTEIRIQRKKENSLDWEDWQYFARNCGAF--GMKNNGDLEKPDSVNCLQLSNFTPYSRGN 451 P + ++R + W ++YF+ +CGA G+ D V + S P + G Sbjct: 157 PAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGE 216 Query: 452 VTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR-----Y 506 V + +L P Y++ +Q +K T +R + + + ++ R Y Sbjct: 217 VIYRVLDPAIPIPDPYSS-----RIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYY 271 Query: 507 YAVDEITISGRCQCHGHADNC-DTTSQPYR--------CLCSQESFTEGLHCDRCLPLYN 557 YA+ E+ + G C C+GHA C P C+C T GL+C++C Y Sbjct: 272 YALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHN--TRGLNCEQCQDFYR 329 Query: 558 DKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGG---GGVCDDCEHNTTG 614 D P+R + ++ C+ C+C+ H+ SCH++++V + G GGVCD C+HNT G Sbjct: 330 DLPWRPAEDGHSHACRKCECHGHTHSCHFDMAV------YLASGNVSGGVCDGCQHNTAG 383 Query: 615 RNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ--------IGGQCNCKR 666 R+CELC+ +F+R D VC+ CDCD +G+++G CD + GQC CK Sbjct: 384 RHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGG-RCDSHDDPALGLVSGQCRCKE 442 Query: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726 HV G +C QC++GF+ L D GC C CN GTV G C NSG C CK V G C Sbjct: 443 HVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGC 502 Query: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY 785 D C G L S + +GC PC C++ G+++ C+ +GQC C++ G +C+ + ++ Sbjct: 503 DRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560 Score = 241 bits (615), Expect = 4e-63 Identities = 141/420 (33%), Positives = 188/420 (44%), Gaps = 49/420 (11%) Query: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTS 699 PC C+ G+ + C+ GGQC CK V GR+C+ C G+Y P GC C C+ Sbjct: 782 PCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQACQCSHE 836 Query: 700 GTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFC 759 G + C + SGQC C+ GLRCD C G + C PC CN H C Sbjct: 837 GALSS--LCEKTSGQCLCRTGAFGLRCDRCQRG-----QWGFPSCRPCVCNGHADE---C 886 Query: 760 NPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT----NCKACDCDTAGSLPGTVCNAKTG- 813 N H+G C C+ G C+ C F+G C+ C C PG+ + T Sbjct: 887 NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEG---PGSQRHFATSC 943 Query: 814 ---------QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864 C C+ G +C C G+F C C C C+ Sbjct: 944 HQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPH 1003 Query: 865 TGQC-PCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI-------CDPI 916 TGQC C G C C+P + Q C C C+ LGT P CDP Sbjct: 1004 TGQCLRCLHHTEGPHCAHCKPGFHGQAAR--QSCHRCTCNLLGTNPQQCPSPDQCHCDPS 1061 Query: 917 SGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDA 975 SGQC C+PN QG C++C P F+ ++ G+ GC PC+CH + A CN TGQC C+ A Sbjct: 1062 SGQCPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHPSRARGPTCNEFTGQCHCR-A 1118 Query: 976 SIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035 G+ C +C++ ++G DP +C C+C G CH TG C C+ V+G +CD C Sbjct: 1119 GFGGRTCSECQELHWG-DPGL-QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQC 1176 Score = 216 bits (550), Expect = 1e-55 Identities = 123/378 (32%), Positives = 178/378 (47%), Gaps = 32/378 (8%) Query: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKF 735 C +L L +G PC CN G++ + C+ + GQC CK V+G RCD C G+ Sbjct: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYY- 821 Query: 736 LRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795 F GC+ CQC+ G+++ C SGQC C+ A GL+CD C+ +G +C+ C Sbjct: 822 --GFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPC 877 Query: 796 DCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEG-NFYLRQNNSFLCLPCNCDK-- 851 C+ CN TG C+ C+ + G C +C+ G + R C PC C + Sbjct: 878 VCNGHAD----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933 Query: 852 TGTINGSLLCNKSTGQ----CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD-SLG 906 + + C++ C C+ G TGLRC C P + CQ+CEC ++ Sbjct: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993 Query: 907 TLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNS 965 + CDP +GQCL C+ + +G C C+PGF+ C C+C+ G C S Sbjct: 994 PMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFH-GQAARQSCHRCTCNLLGTNPQQCPS 1052 Query: 966 --------LTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLV 1017 +GQC C ++ G CD+C +++ G CQPC CH S A TC+ Sbjct: 1053 PDQCHCDPSSGQCPCL-PNVQGPSCDRCAPNFWNLTSGHG-CQPCACHPSRARGPTCNEF 1110 Query: 1018 TGQCFCKQFVTGSKCDAC 1035 TGQC C+ G C C Sbjct: 1111 TGQCHCRAGFGGRTCSEC 1128 Score = 176 bits (445), Expect = 2e-43 Identities = 141/495 (28%), Positives = 194/495 (39%), Gaps = 92/495 (18%) Query: 518 CQCHGHAD-NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN---CK 573 CQC+ + + +CLC G CD C P Y Y F C+ Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPG--VVGRRCDLCAPGY-----------YGFGPTGCQ 829 Query: 574 PCQCNSH---SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630 CQC+ S C G C C G C+ C+ R Sbjct: 830 ACQCSHEGALSSLCEKT--------------SGQCL-CRTGAFGLRCDRCQ----RGQWG 870 Query: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPD 689 PS C+PC C+ C+ G C C+ H G C +C GF+ L Sbjct: 871 FPS----CRPCVCNGHADE-----CNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921 Query: 690 G-CSPCNCNTSGTVDGDI--TCHQNSGQ----CKCKANVIGLRCDHCNFGFKFLRSFNDV 742 G C PC C +CHQ+ C C+A GLRC+ C G S Sbjct: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981 Query: 743 GCEPCQCNLHGSVNKF----CNPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT-NCKACD 796 C+ C+C+ G+++ C+PH+GQC C +G C C+ F+G +C C Sbjct: 982 RCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCT 1039 Query: 797 CDTAGSLPGTV-------CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849 C+ G+ P C+ +GQC C PNV+G C++C + L + C PC C Sbjct: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHG--CQPCAC 1097 Query: 850 DKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909 + + CN+ TGQC C+ G G C++C+ + D C C+CDS G + Sbjct: 1098 HPSRARGPT--CNEFTGQCHCRAGFGGRTCSECQELHWG---DPGLQCHACDCDSRG-ID 1151 Query: 910 GTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQ 969 C +G C C P G RC+QC GF G C PC H C Sbjct: 1152 TPQCHRFTGHCSCRPGVSGVRCDQCARGF---SGIFPACHPC---------HACFG-DWD 1198 Query: 970 CVCQDASIAGQRCDQ 984 V QD + QR +Q Sbjct: 1199 RVVQDLAARTQRLEQ 1213 Score = 150 bits (379), Expect = 9e-36 Identities = 87/255 (34%), Positives = 122/255 (47%), Gaps = 30/255 (11%) Query: 713 GQCKCKANVIGLRCDHCNFGFKFL-----RSFNDVGCEPCQCNLHGSVNKFC-------- 759 G C CK N GL C+ C ++ L + C C+C+ H F Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367 Query: 760 NPHSGQCE-CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAK- 811 N G C+ C+ G C+ CR FY D C++CDCD GS G C++ Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427 Query: 812 -------TGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864 +GQC CK +V G +C +C +G F L ++ C C C+ GT+ GS C+ + Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487 Query: 865 TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924 +G C CK VTG C++C P + L+ D C+ C+CD G L CD +GQC C Sbjct: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHD-LLGCRPCDCDVGGALDPQ-CDEGTGQCHCRQ 545 Query: 925 NRQGRRCNQCQPGFY 939 + GRRC Q QPG++ Sbjct: 546 HMVGRRCEQVQPGYF 560 Score = 144 bits (363), Expect = 7e-34 Identities = 84/262 (32%), Positives = 122/262 (46%), Gaps = 44/262 (16%) Query: 764 GQCECKKEAKGLQCDTCRENFYGLDVTN--------CKACDCD--------------TAG 801 G C CK +GL C+ C++ + L C+ C+C +G Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367 Query: 802 SLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL-----CLPCNCDKTGTIN 856 ++ G VC+ C+ N GR C C F+ R L C C+CD G+ + Sbjct: 368 NVSGGVCDG------CQHNTAGRHCELCRP--FFYRDPTKDLRDPAVCRSCDCDPMGSQD 419 Query: 857 GSLLCNKS-------TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909 G + +GQC CK V G RC QC + L+I + C+ C+C++ GT+P Sbjct: 420 GGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVP 479 Query: 910 G-TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTG 968 G T CDP SG C C GR C++C PG + + GC PC C GA++ C+ TG Sbjct: 480 GSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTG 539 Query: 969 QCVCQDASIAGQRCDQCKDHYF 990 QC C+ + G+RC+Q + YF Sbjct: 540 QCHCRQ-HMVGRRCEQVQPGYF 560 Score = 140 bits (352), Expect = 1e-32 Identities = 97/352 (27%), Positives = 152/352 (43%), Gaps = 39/352 (11%) Query: 794 ACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFY-------LRQNNSFLCLP 846 A +C A P G CICK N G C +C + FY +S C Sbjct: 289 ASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQD--FYRDLPWRPAEDGHSHACRK 346 Query: 847 CNCD-KTGTINGSLLC-----NKSTGQCP-CKLGVTGLRCNQCEPHRYNLTIDNFQH--- 896 C C T + + + N S G C C+ G C C P Y + + Sbjct: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406 Query: 897 CQMCECDSLGTLPGTICDP--------ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947 C+ C+CD +G+ G CD +SGQC C + G RC QC+ GF+ +S + G Sbjct: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLG 466 Query: 948 CLPCSCHTTGAV--NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCH 1005 C C C+ G V + C+ +G C C+ + G+ CD+C ++G C+PC+C Sbjct: 467 CRRCQCNARGTVPGSTPCDPNSGSCYCKRL-VTGRGCDRCLPGHWGLSHDLLGCRPCDCD 525 Query: 1006 LSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQ 1065 + GAL+ C TGQC C+Q + G +C+ P +++L+ ++ RGQV Sbjct: 526 VGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLI------WEAEDTRGQV- 578 Query: 1066 SSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLP 1117 + +P ++P+ + L++G + P ++ Y L L P Sbjct: 579 -LDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPKAMDYDLLLRLEP 629 Score = 39.3 bits (90), Expect = 0.030 Identities = 34/115 (29%), Positives = 45/115 (39%), Gaps = 27/115 (23%) Query: 517 RCQCHGH-----ADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN 571 RCQC+ + CD S C C + G CDRCLP + G Sbjct: 469 RCQCNARGTVPGSTPCDPNSGS--CYCKR--LVTGRGCDRCLPGH------WGLSHDLLG 518 Query: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFR 626 C+PC C+ ++DP E G G C C + GR CE + +FR Sbjct: 519 CRPCDCDVGG-------ALDPQCDE----GTGQCH-CRQHMVGRRCEQVQPGYFR 561 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 264 bits (674), Expect = 6e-70 Identities = 161/496 (32%), Positives = 227/496 (45%), Gaps = 67/496 (13%) Query: 492 QYYTTETAVNLRHRYYAVDEITISGRCQ---CHGHADNCDTTSQPYRCLCSQESFTEGLH 548 Q YT + + YY VD I G CQ CHGHA C+ C + T G+H Sbjct: 713 QGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHN----TTGVH 768 Query: 549 CDRCLPLYNDKPFR--QGDQVYAFNCKPCQC------NSHSKSCHYNISVDPFPFEHFRG 600 C++CLP + +P R GD C+PC C N+ S +CH N G Sbjct: 769 CEQCLPGFYGEPSRGTPGD------CQPCACPLTIASNNFSPTCHLN-----------DG 811 Query: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 VCD C +G CE C D ++ G + C PCDC + + CD + G Sbjct: 812 DEVVCDWCAPGYSGAWCERCADGYY---GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTG 868 Query: 661 QC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKA 719 +C C + G C +C +GFY + C C C+ G+ CH +G C CK Sbjct: 869 ECLKCLGNTDGAHCERCADGFYG-DAVTAKNCRACECHVKGS--HSAVCHLETGLCDCKP 925 Query: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779 NV G +CD C G+ L S + GC PC C++ GSV+ C GQC C G +CD Sbjct: 926 NVTGQQCDQCLHGYYGLDSGH--GCRPCNCSVAGSVSDGCT-DEGQCHCVPGVAGKRCDR 982 Query: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839 C FY +C CDC + C+ +TG+C+C P+ +G +C +C +G++ + Sbjct: 983 CAHGFYAYQDGSCTPCDCPHTQN----TCDPETGECVCPPHTQGVKCEECEDGHW--GYD 1036 Query: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899 C CNC G+ + C+ TG C CK G C+QC +L +F C Sbjct: 1037 AEVGCQACNCSLVGSTHHR--CDVVTGHCQCKSKFGGRACDQC-----SLGYRDFPDCVP 1089 Query: 900 CECDSLGT------LPGTICDPI--SGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLP 950 C+CD GT L +C + +G C C N G +CN+C+ G F + N GC P Sbjct: 1090 CDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSP 1149 Query: 951 CSCHTTGAVNHICNSL 966 C C ++H+C+ L Sbjct: 1150 CFC---SGLSHLCSEL 1162 Score = 260 bits (665), Expect = 6e-69 Identities = 156/465 (33%), Positives = 217/465 (46%), Gaps = 46/465 (9%) Query: 607 DCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKR 666 +C TG +CE C ++R G I C+PC+C + C+ G C Sbjct: 710 ECPQGYTGTSCESCLSGYYRVDGILFGGI--CQPCEC-----HGHAAECNVHGVCIACAH 762 Query: 667 HVSGRQCNQCQNGFYNLQELD-PDGCSPCNCN-TSGTVDGDITCHQNSGQ---CK-CKAN 720 + +G C QC GFY P C PC C T + + TCH N G C C Sbjct: 763 NTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPG 822 Query: 721 VIGLRCDHCNFGFKFLRSFNDVGCEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAKGLQC 777 G C+ C G+ + C PC C N+ S C+ +G+C +C G C Sbjct: 823 YSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882 Query: 778 DTCRENFYGLDVT--NCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFY 835 + C + FYG VT NC+AC+C GS VC+ +TG C CKPNV G+QC++CL G + Sbjct: 883 ERCADGFYGDAVTAKNCRACECHVKGS-HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYG 941 Query: 836 LRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895 L + C PCNC G+++ GQC C GV G RC++C H + D Sbjct: 942 LDSGHG--CRPCNCSVAGSVSDGCT---DEGQCHCVPGVAGKRCDRCA-HGFYAYQDG-- 993 Query: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHT 955 C C+C CDP +G+C+C P+ QG +C +C+ G + GC C+C Sbjct: 994 SCTPCDCPHTQNT----CDPETGECVCPPHTQGVKCEECEDGHWGYDAEV-GCQACNCSL 1048 Query: 956 TGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCH 1015 G+ +H C+ +TG C C+ + G+ CDQC Y F C PC+C L G + C+ Sbjct: 1049 VGSTHHRCDVVTGHCQCK-SKFGGRACDQCSLGYRDFPD----CVPCDCDLRGTSGDACN 1103 Query: 1016 LV---------TGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051 L TG C CK+ V G +C+ C L +N LGCS Sbjct: 1104 LEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCS 1148 Score = 257 bits (656), Expect = 7e-68 Identities = 163/503 (32%), Positives = 234/503 (46%), Gaps = 73/503 (14%) Query: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595 C C Q +T G C+ CL Y +R ++ C+PC+C+ H+ C+ + Sbjct: 709 CECPQ-GYT-GTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH-------- 754 Query: 596 EHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPS--AIDVCKPCDCD-TVGTRNGS 652 GVC C HNTTG +CE C F+ +PS C+PC C T+ + N S Sbjct: 755 -------GVCIACAHNTTGVHCEQCLPGFY----GEPSRGTPGDCQPCACPLTIASNNFS 803 Query: 653 ILCDQIGGQ---CN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITC 708 C G C+ C SG C +C +G+Y + + C PC+C SG VD Sbjct: 804 PTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDC--SGNVDPSEAG 861 Query: 709 HQNS--GQC-KCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765 H +S G+C KC N G C+ C GF + + C C+C++ GS + C+ +G Sbjct: 862 HCDSVTGECLKCLGNTDGAHCERCADGF-YGDAVTAKNCRACECHVKGSHSAVCHLETGL 920 Query: 766 CECKKEAKGLQCDTCRENFYGLDVTN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGR 824 C+CK G QCD C +YGLD + C+ C+C AGS+ + GQC C P V G+ Sbjct: 921 CDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD--EGQCHCVPGVAGK 978 Query: 825 QCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEP 884 +C++C G FY Q+ S C PC+C T C+ TG+C C G++C +CE Sbjct: 979 RCDRCAHG-FYAYQDGS--CTPCDCPHTQN-----TCDPETGECVCPPHTQGVKCEECED 1030 Query: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGN 944 + D CQ C C +G+ CD ++G C C GR C+QC G+ P Sbjct: 1031 GHWG--YDAEVGCQACNCSLVGSTHHR-CDVVTGHCQCKSKFGGRACDQCSLGYRDFP-- 1085 Query: 945 ATGCLPCSCHTTGAVNHICN---------SLTGQCVCQDASIAGQRCDQCKDHYFGF--D 993 C+PC C G CN TG C C++ ++ G +C++C++ F D Sbjct: 1086 --DCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE-NVFGPQCNECREGTFALRAD 1142 Query: 994 PQTGRCQPCNC----HLSGALNE 1012 G C PC C HL L + Sbjct: 1143 NPLG-CSPCFCSGLSHLCSELED 1164 Score = 220 bits (561), Expect = 7e-57 Identities = 131/403 (32%), Positives = 195/403 (48%), Gaps = 35/403 (8%) Query: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQCKCKAN 720 C C + +G C C +G+Y + + G C PC C+ C+ + C N Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAA-----ECNVHGVCIACAHN 763 Query: 721 VIGLRCDHCNFGFKFLRSFNDVG-CEPCQCNLHGSVNKF---CNPHSGQ---CE-CKKEA 772 G+ C+ C GF S G C+PC C L + N F C+ + G C+ C Sbjct: 764 TTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGY 823 Query: 773 KGLQCDTCRENFYGLDVTNCKAC-DCDTAGSLPGTV---CNAKTGQCI-CKPNVEGRQCN 827 G C+ C + +YG ++C CD +G++ + C++ TG+C+ C N +G C Sbjct: 824 SGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE 883 Query: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRY 887 +C +G FY + C C C G+ S +C+ TG C CK VTG +C+QC Y Sbjct: 884 RCADG-FYGDAVTAKNCRACECHVKGS--HSAVCHLETGLCDCKPNVTGQQCDQCLHGYY 940 Query: 888 NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATG 947 L D+ C+ C C G++ D GQC CVP G+RC++C GFY + Sbjct: 941 GL--DSGHGCRPCNCSVAGSVSDGCTD--EGQCHCVPGVAGKRCDRCAHGFYAYQDGS-- 994 Query: 948 CLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLS 1007 C PC C T + C+ TG+CVC + G +C++C+D ++G+D + G CQ CNC L Sbjct: 995 CTPCDCPHT---QNTCDPETGECVCPPHT-QGVKCEECEDGHWGYDAEVG-CQACNCSLV 1049 Query: 1008 GALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 G+ + C +VTG C CK G CD C S + D + + C Sbjct: 1050 GSTHHRCDVVTGHCQCKSKFGGRACDQC--SLGYRDFPDCVPC 1090 Score = 197 bits (500), Expect = 9e-50 Identities = 143/453 (31%), Positives = 206/453 (45%), Gaps = 61/453 (13%) Query: 336 NP-EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFFS-PQ 393 NP E HP+S D W S N + + VTI++DL +QV Y+II+ + P+ Sbjct: 75 NPRERHPISHAIDG-TNNWWQSPSIQNGREYHW-VTITLDLRQ-VFQVAYVIIKAANAPR 131 Query: 394 PTEIRIQRKKENSLDWEDWQYFARNCGAFGMKNN-------GDLEKPDSVNCLQL-SNFT 445 P ++R + + + WQY+A + + N D V C S Sbjct: 132 PGNWILERSLDGTT-FSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYSRLV 190 Query: 446 PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR 505 P G + S++ N RP ++ +P L EF A IR + L HR Sbjct: 191 PLEHGEIHTSLI----NGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLSHR 244 Query: 506 -------------YYAVDEITISGRCQCHGHADNC--DTTSQPYRCLCSQESFTEGLHCD 550 YY++ +I++ G C C+GHA +C D T++ +C C E T G C+ Sbjct: 245 EPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQC--EHNTCGESCN 302 Query: 551 RCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-----HFRGGGGVC 605 RC P Y+ +P+R G C+ C C++ +K C+Y+ SV FR GGGVC Sbjct: 303 RCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFR-GGGVC 361 Query: 606 DDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQI------- 658 +C NT G NCE C D ++R P + C+PC+CD VG+ + + D + Sbjct: 362 INCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNG 421 Query: 659 --GGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716 GQC CK +G +C++CQ G+ D C C CN G+ D C +G C Sbjct: 422 KQPGQCPCKEGYTGEKCDRCQLGY-----KDYPTCVSCGCNPVGSA-SDEPC---TGPCV 472 Query: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749 CK NV G CD C GF L+ N GC C C Sbjct: 473 CKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505 Score = 118 bits (296), Expect = 4e-26 Identities = 82/284 (28%), Positives = 109/284 (38%), Gaps = 45/284 (15%) Query: 787 LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF---L 843 LD+ + A D A A C C G C CL G Y R + + Sbjct: 690 LDIASSNAIDLVVA---------ADVEHCECPQGYTGTSCESCLSG--YYRVDGILFGGI 738 Query: 844 CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ-HCQMCEC 902 C PC C + CN C TG+ C QC P Y CQ C C Sbjct: 739 CQPCECH-----GHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCAC 793 Query: 903 D------------SLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPG-NATGCL 949 L +CD C P G C +C G+Y +P C+ Sbjct: 794 PLTIASNNFSPTCHLNDGDEVVCD------WCAPGYSGAWCERCADGYYGNPTVPGESCV 847 Query: 950 PCSCHTT---GAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006 PC C H C+S+TG+C+ + G C++C D ++G C+ C CH+ Sbjct: 848 PCDCSGNVDPSEAGH-CDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHV 906 Query: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 G+ + CHL TG C CK VTG +CD C+ LD + GC Sbjct: 907 KGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGH--GC 948 Score = 111 bits (278), Expect = 5e-24 Identities = 83/302 (27%), Positives = 132/302 (43%), Gaps = 57/302 (18%) Query: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739 +Y+++++ G C + S + T QC+C+ N G C+ C G+ Sbjct: 258 YYSIKDISVGGMCICYGHASSCPWDETT---KKLQCQCEHNTCGESCNRCCPGYHQ---- 310 Query: 740 NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799 +P + S N C C C +AK + +Y V K +T Sbjct: 311 -----QPWRPGTVSSGNT-CEA----CNCHNKAK--------DCYYDESVAKQKK-SLNT 351 Query: 800 AGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTI 855 AG G G CI C N G C C++G + + + + C PCNCD G++ Sbjct: 352 AGQFRGG------GVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL 405 Query: 856 NG---------SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906 + L K GQCPCK G TG +C++C+ L ++ C C C+ +G Sbjct: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ-----LGYKDYPTCVSCGCNPVG 460 Query: 907 TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNS 965 + +P +G C+C N +G+ C++C+PGFY + N GC C C V+ +C+S Sbjct: 461 SASD---EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCF---GVSDVCSS 514 Query: 966 LT 967 L+ Sbjct: 515 LS 516 Score = 111 bits (278), Expect = 5e-24 Identities = 71/239 (29%), Positives = 101/239 (42%), Gaps = 52/239 (21%) Query: 661 QCNCKRHVSGRQCNQCQNGFYNLQELDP------DGCSPCNC------------------ 696 QC C+ + G CN+C G Y+ Q P + C CNC Sbjct: 289 QCQCEHNTCGESCNRCCPG-YHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKK 347 Query: 697 --NTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGF---KFLRSFNDVGCEPCQCNL 751 NT+G G C C N +G+ C+ C G+ + + D C PC C+ Sbjct: 348 SLNTAGQFRGGGVC------INCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDP 401 Query: 752 HGSVNKFC---NPHS--------GQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTA 800 GS++ C + HS GQC CK+ G +CD C+ + D C +C C+ Sbjct: 402 VGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYK--DYPTCVSCGCNPV 459 Query: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSL 859 GS C TG C+CK NVEG+ C++C G + L++ N C C C + SL Sbjct: 460 GSASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSL 515 Score = 105 bits (263), Expect = 3e-22 Identities = 63/212 (29%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 715 CKCKANVIGLRCDHCNFGFKF--LRSFNDVG-------CEPCQCNLHGSVNKFCNPHSGQ 765 C C +G C C G+ L + +D G C PC CN H C+P++G+ Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT---CDPNTGK 1418 Query: 766 C-ECKKEAKGLQCDTCRENFYGL---DVTNCKACDCD---TAGSLPGTVCNAKTG-QC-I 816 C C G CD C +YG ++C C C A P V +C Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478 Query: 817 CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTG 876 C EG+ C +C + Q C C+C+ G+++G C++++GQC C+LG +G Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD--CDRTSGQCVCRLGASG 1536 Query: 877 LRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908 LRC++CEP + D C C+ + +G L Sbjct: 1537 LRCDECEPRHILMETD----CVSCDDECVGVL 1564 Score = 100 bits (248), Expect = 1e-20 Identities = 64/207 (30%), Positives = 93/207 (44%), Gaps = 17/207 (8%) Query: 608 CEHNTTGRNCELCKDYFFR---QVGADPSA---IDVCKPCDCDTVGTRNGSILCDQIGGQ 661 C T G +C+ C + R G+D + C PC C+ N S CD G+ Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN-----NHSDTCDPNTGK 1418 Query: 662 C-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCH-QNSGQCKCKA 719 C NC + +G C+ C +G+Y C+ C C S TC + +C A Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478 Query: 720 NVIGLR---CDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQ 776 ++G C+ C+ + C+ C CN HGSV+ C+ SGQC C+ A GL+ Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538 Query: 777 CDTCRENFYGLDVTNCKACDCDTAGSL 803 CD C E + L T+C +CD + G L Sbjct: 1539 CDEC-EPRHILMETDCVSCDDECVGVL 1564 Score = 99.0 bits (245), Expect = 3e-20 Identities = 60/202 (29%), Positives = 85/202 (42%), Gaps = 29/202 (14%) Query: 536 CLCSQESFTEGLHCDRCLPLYNDKPFR----QGDQVYAFNCKPCQCNSHSKSCHYNISVD 591 C+C T G C C P Y+ +G + C PC CN+HS +C N Sbjct: 1362 CVCPPG--TVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNT--- 1416 Query: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNG 651 G C +C NT G +C++C ++ +V S C C C + Sbjct: 1417 -----------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASD---CALCACPHSPPASF 1462 Query: 652 SILCDQIGG---QCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDIT 707 S C G +C+ C G+ C +C + +Y + C C+CN G+V GD Sbjct: 1463 SPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD-- 1520 Query: 708 CHQNSGQCKCKANVIGLRCDHC 729 C + SGQC C+ GLRCD C Sbjct: 1521 CDRTSGQCVCRLGASGLRCDEC 1542 Score = 96.3 bits (238), Expect = 2e-19 Identities = 62/194 (31%), Positives = 91/194 (46%), Gaps = 35/194 (18%) Query: 868 CPCKLGVTGLRCNQCEP--HRYNLTIDNFQH-------CQMCECDSLGTLPGTICDPISG 918 C C G G C C P HR L + + C C C++ CDP +G Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNN----HSDTCDPNTG 1417 Query: 919 QCL-CVPNRQGRRCNQCQPGFYIS-PGNATGCLPCSC-HTTGAVNHICNSLTGQCVCQ-- 973 +CL C N G C+ C G+Y G+A+ C C+C H+ A S + CV + Sbjct: 1418 KCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPA------SFSPTCVLEGD 1471 Query: 974 -----DASIAG---QRCDQCKDHYFGFDPQT--GRCQPCNCHLSGALNETCHLVTGQCFC 1023 DA + G + C++C Y+G +PQT G CQ C+C+ G+++ C +GQC C Sbjct: 1472 HDFRCDACLLGYEGKHCERCSSSYYG-NPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVC 1530 Query: 1024 KQFVTGSKCDACVP 1037 + +G +CD C P Sbjct: 1531 RLGASGLRCDECEP 1544 Score = 92.0 bits (227), Expect = 4e-18 Identities = 63/228 (27%), Positives = 92/228 (40%), Gaps = 56/228 (24%) Query: 867 QCPCKLGVTGLRCNQCEPHRYNL-----TIDNFQHCQMCEC------------------- 902 QC C+ G CN+C P + T+ + C+ C C Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348 Query: 903 -DSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFY----ISPGNATGCLPCSCHTT 956 ++ G G G C+ C+ N G C C G+Y +SP C PC+C Sbjct: 349 LNTAGQFRG------GGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPV 402 Query: 957 GAVNHIC-----------NSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCH 1005 G+++ +C GQC C++ G++CD+C+ Y + C C C+ Sbjct: 403 GSLSSVCIKDDLHSDLHNGKQPGQCPCKEG-YTGEKCDRCQLGYKDYPT----CVSCGCN 457 Query: 1006 LSG-ALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052 G A +E C TG C CK+ V G CD C P +L N GCS+ Sbjct: 458 PVGSASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSE 502 Score = 84.0 bits (206), Expect = 1e-15 Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 25/211 (11%) Query: 766 CECKKEAKGLQCDTCRENFY------GLD------VTNCKACDCDTAGSLPGTVCNAKTG 813 C C G C C ++ G D V C C C+ C+ TG Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD----TCDPNTG 1417 Query: 814 QCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLC---NKSTGQCP 869 +C+ C N G C+ C G + ++ C C C + + S C +C Sbjct: 1418 KCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCD 1477 Query: 870 -CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQG 928 C LG G C +C Y CQ C+C+ G++ G CD SGQC+C G Sbjct: 1478 ACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD-CDRTSGQCVCRLGASG 1536 Query: 929 RRCNQCQPGFYISPGNATGCLPCSCHTTGAV 959 RC++C+P + T C+ C G + Sbjct: 1537 LRCDECEPRHILM---ETDCVSCDDECVGVL 1564 Score = 75.1 bits (183), Expect = 5e-13 Identities = 55/189 (29%), Positives = 84/189 (44%), Gaps = 23/189 (12%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 C C+ H+D CD + +CL ++ T G HCD C Y K A +C C C Sbjct: 1403 CSCNNHSDTCDPNTG--KCLNCGDN-TAGDHCDVCTSGYYGKVTGS-----ASDCALCAC 1454 Query: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDV 637 HS ++ + FR CD C G++CE C ++ G + Sbjct: 1455 -PHSPPASFSPTCVLEGDHDFR-----CDACLLGYEGKHCERCSSSYY---GNPQTPGGS 1505 Query: 638 CKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCN 697 C+ CDC+ G+ +G CD+ GQC C+ SG +C++C+ + L E D C C+ Sbjct: 1506 CQKCDCNPHGSVHGD--CDRTSGQCVCRLGASGLRCDECEPR-HILMETD---CVSCDDE 1559 Query: 698 TSGTVDGDI 706 G + D+ Sbjct: 1560 CVGVLLNDL 1568 >gi|143770880 laminin, beta 4 [Homo sapiens] Length = 1761 Score = 251 bits (642), Expect = 3e-66 Identities = 137/439 (31%), Positives = 221/439 (50%), Gaps = 46/439 (10%) Query: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG-AFGMKNN 427 V+I +DLE ++ ++I+ F + +P + ++R + +W+ ++YFA++C +F + Sbjct: 114 VSIRLDLE-ALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITS 172 Query: 428 GDLEKPDSVNC-LQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIR 486 G + + C + S+ P + G V +L P Y+ P +Q+ V T +R Sbjct: 173 GQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYS-----PYIQDLVTLTNLR 227 Query: 487 FHFHGQYYTTETAVNLRHR------YYAVDEITISGRCQCHGHADNC--------DTTSQ 532 +F + + + R YYA+ E+ + G C C+GHA C D S Sbjct: 228 INFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSP 287 Query: 533 PY----RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNI 588 P +C+C T+G +C+RC + D P+R + C+ C CNSHS CH+++ Sbjct: 288 PGMVHGQCVCQHN--TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDM 345 Query: 589 SVDPFPFEHFRGGG---GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645 + + GG GVC+DC+HNT G++C+ C+ F+R S C PC+CD Sbjct: 346 TT------YLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDP 399 Query: 646 VGTRNGSILCD-------QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698 GT +G I + GQC CK +V G +C+QC+ Y L DP GC PC+CN Sbjct: 400 DGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNP 459 Query: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKF 758 G++ +TC ++GQC C + V G C+ C G+ L + GC PC C++ G+ + Sbjct: 460 LGSLP-FLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLH-GCSPCDCDIGGAYSNV 517 Query: 759 CNPHSGQCECKKEAKGLQC 777 C+P +GQCEC+ G C Sbjct: 518 CSPKNGQCECRPHVTGRSC 536 Score = 248 bits (634), Expect = 2e-65 Identities = 135/415 (32%), Positives = 196/415 (47%), Gaps = 42/415 (10%) Query: 641 CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSG 700 C C G+ S C ++GGQC CK V GR C++C G Y+L GC PC+C+ G Sbjct: 769 CKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGH---HGCHPCHCHPQG 823 Query: 701 TVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN 760 + D C Q +GQC C V G RCD C G+ F C PC CN + C+ Sbjct: 824 SKD--TVCDQVTGQCPCHGEVSGRRCDRCLAGY-----FGFPSCHPCPCNRFAEL---CD 873 Query: 761 PHSGQC-ECKKEAKGLQCDTCRENFYGLDVTN--CKACDCDTAGSLPGTVCNAKTGQ--- 814 P +G C C G C+ C + +YG + C+ C C S ++ Sbjct: 874 PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933 Query: 815 ----CICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-P 869 C C G QC +C G + + + C PC C+ + C++ TG+C Sbjct: 934 SDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993 Query: 870 CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP--------GTICDPISGQCL 921 C G C C+P Y ++ Q C+ C C + G P +CDP++G C Sbjct: 994 CLHNTQGANCQLCKPGHYGSALN--QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051 Query: 922 CVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980 C+PN G C++C G++ + PG GC C C + + C+ LTGQC C+ G+ Sbjct: 1052 CLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPRTSQSSHCDQLTGQCPCK-LGYGGK 1108 Query: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035 RC +C+++Y+G P GRC PC+C+ +G C TG C C++ V+G +CD C Sbjct: 1109 RCSECQENYYGDPP--GRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161 Score = 186 bits (472), Expect = 2e-46 Identities = 128/446 (28%), Positives = 179/446 (40%), Gaps = 76/446 (17%) Query: 518 CQCHGHADNCDTTSQ-PYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQ 576 C+CH + S+ +C C + G CDRC D C PC Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQC--KPLVVGRCCDRCSTGSYDLGHH--------GCHPCH 818 Query: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCDD------CEHNTTGRNCELCKDYFFRQVGA 630 C+ VCD C +GR C+ C +F Sbjct: 819 CHPQGSK------------------DTVCDQVTGQCPCHGEVSGRRCDRCLAGYF----- 855 Query: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPD 689 C PC C+ LCD G C NC +GR C +C +G+Y Sbjct: 856 ---GFPSCHPCPCNRFAE-----LCDPETGSCFNCGGFTTGRNCERCIDGYYG-NPSSGQ 906 Query: 690 GCSPCNC--NTSGTVDGDITCHQNSGQ----CKCKANVIGLRCDHCNFGFKFLRSFNDVG 743 C PC C + S +C+QN C C G +C C+ GF + Sbjct: 907 PCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAP 966 Query: 744 CEPCQCNLHGSVN--KFCNPHSGQC-ECKKEAKGLQCDTCRENFYGLDVTN-CKACDCDT 799 C+PC CN + V + C+ +G+C C +G C C+ YG + C+ C C Sbjct: 967 CQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHA 1026 Query: 800 AGSLP--------GTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK 851 +G P +C+ TG C C PNV G C++C +G + L C C+CD Sbjct: 1027 SGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRG--CQSCDCDP 1084 Query: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGT 911 + S C++ TGQCPCKLG G RC++C+ + Y D C C+C+ GT Sbjct: 1085 R--TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQK-P 1138 Query: 912 ICDPISGQCLCVPNRQGRRCNQCQPG 937 ICDP +G C C G+RC++C G Sbjct: 1139 ICDPDTGMCRCREGVSGQRCDRCARG 1164 Score = 162 bits (411), Expect = 2e-39 Identities = 113/363 (31%), Positives = 146/363 (40%), Gaps = 84/363 (23%) Query: 743 GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGS 802 G C+C+ GSV C+ GQC+CK G CD C Y L C C C GS Sbjct: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824 Query: 803 LPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCN 862 TVC+ TGQC C V GR+C++CL G F C PC C++ LC+ Sbjct: 825 -KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS-----CHPCPCNRFAE-----LCD 873 Query: 863 KSTGQC-PCKLGVTGLRCNQC-----------EPHRYNLTIDN------FQH-------- 896 TG C C TG C +C +P R L D+ F H Sbjct: 874 PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933 Query: 897 ---------------CQMCECDSLGT--LPGTICDP-----------------ISGQCL- 921 C C G + G C P ++G+CL Sbjct: 934 SDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993 Query: 922 CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNH---------ICNSLTGQCVC 972 C+ N QG C C+PG Y S N T C CSCH +G +C+ +TG C C Sbjct: 994 CLHNTQGANCQLCKPGHYGSALNQT-CRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052 Query: 973 QDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKC 1032 ++ G CD+C D Y+ P G CQ C+C + + C +TGQC CK G +C Sbjct: 1053 L-PNVTGLACDRCADGYWNLVPGRG-CQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRC 1110 Query: 1033 DAC 1035 C Sbjct: 1111 SEC 1113 Score = 160 bits (406), Expect = 7e-39 Identities = 102/343 (29%), Positives = 147/343 (42%), Gaps = 65/343 (18%) Query: 671 RQCNQCQNGFYNLQELDPDGCSPCN-----CNTSGTVDGDITCHQNS--GQCKCKANVIG 723 RQ + +Y L E+ G CN C + GD+ GQC C+ N G Sbjct: 244 RQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDG 303 Query: 724 LRCDHCNFGFKFL-----RSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCD 778 C+ C F+ D C C CN HS +C Sbjct: 304 PNCERCKDFFQDAPWRPAADLQDNACRSCS----------CNSHSSRCH----------- 342 Query: 779 TCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ 838 D+T A +G L G VC C+ N EG+ C++C FY Sbjct: 343 --------FDMTTYLA-----SGGLSGGVCED------CQHNTEGQHCDRC-RPLFYRDP 382 Query: 839 ----NNSFLCLPCNCDKTGTINGSLLCNKS-------TGQCPCKLGVTGLRCNQCEPHRY 887 ++ + C+PC CD GTI+G + + S GQC CK V G +C+QC+P+ Y Sbjct: 383 LKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY 442 Query: 888 NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATG 947 L+ + CQ C+C+ LG+LP CD +GQCLC+ G C +C G++ + G Sbjct: 443 GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG 502 Query: 948 CLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF 990 C PC C GA +++C+ GQC C+ + G+ C + YF Sbjct: 503 CSPCDCDIGGAYSNVCSPKNGQCECR-PHVTGRSCSEPAPGYF 544 Score = 160 bits (405), Expect = 9e-39 Identities = 110/381 (28%), Positives = 148/381 (38%), Gaps = 97/381 (25%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 C CH DT C G CDRCL Y P +C PC C Sbjct: 817 CHCHPQGSK-DTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPC 865 Query: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDV 637 N ++ C DP G C +C TTGRNCE C D ++ +PS+ Sbjct: 866 NRFAELC------DPET--------GSCFNCGGFTTGRNCERCIDGYY----GNPSSGQP 907 Query: 638 CKPCDC--DTVGTRNGSILCDQIGGQ----CNCKRHVSGRQCNQCQNGFY---------- 681 C+PC C D + + C Q CNC + +G QC +C GFY Sbjct: 908 CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPC 967 Query: 682 -------NLQELDPDGCSP-----------------------------------CNCNTS 699 N+ DP+ CS C+C+ S Sbjct: 968 QPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHAS 1027 Query: 700 GTVD-------GDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLH 752 G G C +G C C NV GL CD C G+ L GC+ C C+ Sbjct: 1028 GVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPR 1085 Query: 753 GSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKT 812 S + C+ +GQC CK G +C C+EN+YG C CDC+ AG+ +C+ T Sbjct: 1086 TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGT-QKPICDPDT 1144 Query: 813 GQCICKPNVEGRQCNKCLEGN 833 G C C+ V G++C++C G+ Sbjct: 1145 GMCRCREGVSGQRCDRCARGH 1165 Score = 147 bits (370), Expect = 1e-34 Identities = 98/313 (31%), Positives = 142/313 (45%), Gaps = 70/313 (22%) Query: 758 FCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCIC 817 FCN H+ +C ++ +G DV S PG V GQC+C Sbjct: 266 FCNGHASECRPMQKMRG-------------DVF-----------SPPGMV----HGQCVC 297 Query: 818 KPNVEGRQCNKCLEGNFYLR---------QNNSFLCLPCNCDK----------TGTINGS 858 + N +G C +C + F+ Q+N+ C C+C+ T +G Sbjct: 298 QHNTDGPNCERCKD--FFQDAPWRPAADLQDNA--CRSCSCNSHSSRCHFDMTTYLASGG 353 Query: 859 LLCNKSTGQCP-CKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPGTIC- 913 L S G C C+ G C++C P Y TI + C CECD GT+ G IC Sbjct: 354 L----SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICV 409 Query: 914 ---DP----ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHI-CN 964 DP ++GQCLC N +G +C+QC+P Y +S + GC PC C+ G++ + C+ Sbjct: 410 SHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCD 469 Query: 965 SLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCK 1024 TGQC+C + + G C++C Y+G C PC+C + GA + C GQC C+ Sbjct: 470 VDTGQCLCL-SYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECR 528 Query: 1025 QFVTGSKCDACVP 1037 VTG C P Sbjct: 529 PHVTGRSCSEPAP 541 Score = 108 bits (269), Expect = 5e-23 Identities = 54/138 (39%), Positives = 74/138 (53%), Gaps = 12/138 (8%) Query: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAV 959 C+C G++ G+ C + GQC C P GR C++C G Y + GC PC CH G+ Sbjct: 769 CKCHPQGSV-GSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHH--GCHPCHCHPQGSK 825 Query: 960 NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG 1019 + +C+ +TGQC C ++G+RCD+C YFGF C PC C+ E C TG Sbjct: 826 DTVCDQVTGQCPCH-GEVSGRRCDRCLAGYFGFPS----CHPCPCN---RFAELCDPETG 877 Query: 1020 QCF-CKQFVTGSKCDACV 1036 CF C F TG C+ C+ Sbjct: 878 SCFNCGGFTTGRNCERCI 895 Score = 78.6 bits (192), Expect = 4e-14 Identities = 52/181 (28%), Positives = 77/181 (42%), Gaps = 32/181 (17%) Query: 901 ECDSLGTLPGTICDP---ISGQCLCVPNRQGRRCNQCQPGFYISPGNATG------CLPC 951 EC + + G + P + GQC+C N G C +C+ F +P C C Sbjct: 273 ECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSC 332 Query: 952 SCHTTGAVNHI-------CNSLTGQCVCQDA--SIAGQRCDQCKDHYFGFDPQT----GR 998 SC++ + H L+G VC+D + GQ CD+C+ ++ +T Sbjct: 333 SCNSHSSRCHFDMTTYLASGGLSGG-VCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391 Query: 999 CQPCNCHLSGALN---------ETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLG 1049 C PC C G ++ V GQC CK+ V G+KCD C P+ L + LG Sbjct: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG 451 Query: 1050 C 1050 C Sbjct: 452 C 452 Score = 78.6 bits (192), Expect = 4e-14 Identities = 35/90 (38%), Positives = 49/90 (54%), Gaps = 3/90 (3%) Query: 947 GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006 G + C CH G+V C+ L GQC C+ + G+ CD+C +D C PC+CH Sbjct: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPL-VVGRCCDRCSTG--SYDLGHHGCHPCHCHP 821 Query: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACV 1036 G+ + C VTGQC C V+G +CD C+ Sbjct: 822 QGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851 Score = 72.0 bits (175), Expect = 4e-12 Identities = 60/222 (27%), Positives = 82/222 (36%), Gaps = 67/222 (30%) Query: 518 CQCHGHADNCDTTSQPYRC-------LCSQ-ESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569 C C+ H+ C Y +C + TEG HCDRC PL+ P + YA Sbjct: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391 Query: 570 FNCKPCQCN-----------SHS-------------------------KSCHYNISV-DP 592 C PC+C+ SHS K HY +S DP Sbjct: 392 --CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDP 449 Query: 593 F-------------PFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCK 639 PF G C C TG +CE C ++ + + C Sbjct: 450 LGCQPCDCNPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGL----GNHLHGCS 504 Query: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFY 681 PCDCD G + +C GQC C+ HV+GR C++ G++ Sbjct: 505 PCDCDIGGAYSN--VCSPKNGQCECRPHVTGRSCSEPAPGYF 544 >gi|145309326 laminin, gamma 1 precursor [Homo sapiens] Length = 1609 Score = 245 bits (626), Expect = 2e-64 Identities = 143/428 (33%), Positives = 227/428 (53%), Gaps = 37/428 (8%) Query: 340 HPLSFVND--NDVGTSWVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFFSPQPTE 396 H +F+ D N T+W + T + + +I++ L G+ + + Y+ ++F + +P Sbjct: 101 HGAAFLTDYNNQADTTWWQSQ-TMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPES 159 Query: 397 IRIQRKKENSLDWEDWQYFARNC-GAFGMKNNGDL----EKPDSVNCLQLSNFTPYSRGN 451 I ++ W +QY++ +C + N G + ++ ++ + S+ +P + GN Sbjct: 160 FAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGN 219 Query: 452 VTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVN----LRHRYY 507 V FS L RP NF N+P LQE+V AT IR + + N L+ YY Sbjct: 220 VAFSTLEG----RPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYY 275 Query: 508 AVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQV 567 A+ + + GRC+C+GHA C ++ + +C+ + T G+ C++CLP +ND+P+R+ Sbjct: 276 AISDFAVGGRCKCNGHASEC-MKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAE 334 Query: 568 YAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627 A C PC CN S+ C++ DP + G GG C +C+ NT G +CE C++ FFR Sbjct: 335 SASECLPCDCNGRSQECYF----DPELYRS-TGHGGHCTNCQDNTDGAHCERCRENFFR- 388 Query: 628 VGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELD 687 +G + + C C C VG+ S CD G+C+CK V G +C++CQ GF++L E Sbjct: 389 LGNN----EACSSCHCSPVGSL--STQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEA- 440 Query: 688 PDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPC 747 GC PC+C+ SG++D C+ +G+C CK NV G C+ C GF L S N GC PC Sbjct: 441 --GCRPCSCDPSGSID---ECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPC 495 Query: 748 QCNLHGSV 755 C H SV Sbjct: 496 FCFGHSSV 503 Score = 197 bits (500), Expect = 9e-50 Identities = 114/356 (32%), Positives = 172/356 (48%), Gaps = 29/356 (8%) Query: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECKK 770 C C G C+ C G++ R ++G C C CN H C+P +G C C+ Sbjct: 690 CTCPVGYGGQFCEMCLSGYR--RETPNLGPYSPCVLCACNGHSET---CDPETGVCNCRD 744 Query: 771 EAKGLQCDTCRENFYGLDV----TNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQ 825 G C+ C + +YG ++C+ C C GS V K C C G++ Sbjct: 745 NTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCP-GGSSCAVVPKTKEVVCTNCPTGTTGKR 803 Query: 826 CNKCLEGNFY--LRQNNSF-LCLPCNCDKTGTINGSLLCNKSTGQC-PCKLGVTGLRCNQ 881 C C +G F L +N LC C C N CN+ TG+C C G C++ Sbjct: 804 CELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDR 863 Query: 882 CEPHRYN--LTIDNFQHCQMCECDSLGTLPG-TICDPISGQCLCVPNRQGRRCNQCQPGF 938 C+ + L + C+ C C+ GT+ + C+P++GQC C+P+ G+ C C PGF Sbjct: 864 CKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGF 923 Query: 939 YISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR 998 Y + + GC C CH G+ N C+ TGQC CQ I GQ C++C+ ++FGF P+ Sbjct: 924 Y-NLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPG-ITGQHCERCEVNHFGFGPEG-- 979 Query: 999 CQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTP 1054 C+PC+CH G+L+ C G+C C++ G++CD C ++ + GC + P Sbjct: 980 CKPCDCHPEGSLSLQCK-DDGRCECREGFVGNRCDQC--EENYFYNRSWPGCQECP 1032 Score = 192 bits (489), Expect = 2e-48 Identities = 108/323 (33%), Positives = 159/323 (49%), Gaps = 26/323 (8%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 C C+GH++ CD P +C+ T G HC++C +D + + +C+PC C Sbjct: 724 CACNGHSETCD----PETGVCNCRDNTAGPHCEKC----SDGYYGDSTAGTSSDCQPCPC 775 Query: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDV 637 S SC +V P E VC +C TTG+ CELC D +F + + Sbjct: 776 PGGS-SC----AVVPKTKEV------VCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRL 824 Query: 638 CKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDGCSPC 694 C+ C C N C+++ G+C C + +G C++C++GF+ L D C C Sbjct: 825 CRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKAC 884 Query: 695 NCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGS 754 NCN GT+ +C+ +GQC+C +V G C C+ GF L+S GCE C C+ GS Sbjct: 885 NCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQ--GCERCDCHALGS 942 Query: 755 VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQ 814 N C+ +GQCEC+ G C+ C N +G CK CDC GSL ++ G+ Sbjct: 943 TNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSL--SLQCKDDGR 1000 Query: 815 CICKPNVEGRQCNKCLEGNFYLR 837 C C+ G +C++C E FY R Sbjct: 1001 CECREGFVGNRCDQCEENYFYNR 1023 Score = 184 bits (467), Expect = 6e-46 Identities = 117/359 (32%), Positives = 163/359 (45%), Gaps = 35/359 (9%) Query: 662 CNCKRHVSGRQCNQCQNGFY----NLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKC 717 C C G+ C C +G+ NL P C C CN TC +G C C Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP--CVLCACNGHSE-----TCDPETGVCNC 742 Query: 718 KANVIGLRCDHCNFGFKF-LRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGL 775 + N G C+ C+ G+ + C+PC C S C C G Sbjct: 743 RDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGK 802 Query: 776 QCDTCRENFYGLD------VTNCKACDCDTAGSLPGTV--CNAKTGQCI-CKPNVEGRQC 826 +C+ C + ++G V C+ C C P V CN TG+C+ C N G C Sbjct: 803 RCELCDDGYFGDPLGRNGPVRLCRLCQCSDNID-PNAVGNCNRLTGECLKCIYNTAGFYC 861 Query: 827 NKCLEGNFY--LRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEP 884 ++C +G F L N + C CNC+ GT+ CN TGQC C VTG C C+P Sbjct: 862 DRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDP 921 Query: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPG 943 YNL + Q C+ C+C +LG+ G CD +GQC C P G+ C +C+ F P Sbjct: 922 GFYNL--QSGQGCERCDCHALGSTNGQ-CDIRTGQCECQPGITGQHCERCEVNHFGFGP- 977 Query: 944 NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPC 1002 GC PC CH G+++ C G+C C++ + G RCDQC+++YF ++ CQ C Sbjct: 978 --EGCKPCDCHPEGSLSLQCKD-DGRCECREGFV-GNRCDQCEENYF-YNRSWPGCQEC 1031 Score = 166 bits (419), Expect = 2e-40 Identities = 105/357 (29%), Positives = 160/357 (44%), Gaps = 30/357 (8%) Query: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667 C G+ CE+C + R+ + C C C+ S CD G CNC+ + Sbjct: 692 CPVGYGGQFCEMCLSGYRRET-PNLGPYSPCVLCACN-----GHSETCDPETGVCNCRDN 745 Query: 668 VSGRQCNQCQNGFYNLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726 +G C +C +G+Y C PC C G+ + + C G RC Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPC-PGGSSCAVVPKTKEVVCTNCPTGTTGKRC 804 Query: 727 DHCN---FGFKFLRSFNDVGCEPCQC--NLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTC 780 + C+ FG R+ C CQC N+ + CN +G+C +C G CD C Sbjct: 805 ELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRC 864 Query: 781 RENFYGLDVT-----NCKACDCDTAGSL-PGTVCNAKTGQCICKPNVEGRQCNKCLEGNF 834 ++ F+G + CKAC+C+ G++ + CN TGQC C P+V G+ C C G + Sbjct: 865 KDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFY 924 Query: 835 YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNF 894 L+ C C+C G+ NG C+ TGQC C+ G+TG C +CE + + + Sbjct: 925 NLQSGQG--CERCDCHALGSTNGQ--CDIRTGQCECQPGITGQHCERCEVNHFGFGPEG- 979 Query: 895 QHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951 C+ C+C G+L D G+C C G RC+QC+ ++ + + GC C Sbjct: 980 --CKPCDCHPEGSLSLQCKD--DGRCECREGFVGNRCDQCEENYFYN-RSWPGCQEC 1031 Score = 126 bits (317), Expect = 1e-28 Identities = 70/215 (32%), Positives = 100/215 (46%), Gaps = 20/215 (9%) Query: 662 CNCKRHVSGRQCNQCQNGFYN-----LQELDPDGCSPCNCN-TSGTVDGDITCHQNSGQ- 714 CNCK + G C +C F + C PC+CN S D ++++G Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364 Query: 715 ---CKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKE 771 C+ N G C+ C F R N+ C C C+ GS++ C+ + G+C CK Sbjct: 365 GHCTNCQDNTDGAHCERCRENF--FRLGNNEACSSCHCSPVGSLSTQCDSY-GRCSCKPG 421 Query: 772 AKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLE 831 G +CD C+ F+ L C+ C CD +GS+ CN +TG+C+CK NVEG C +C Sbjct: 422 VMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE--CNIETGRCVCKDNVEGFNCERCKP 479 Query: 832 GNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG 866 G F L +N C PC C S +C + G Sbjct: 480 GFFNLESSNPRGCTPCFC-----FGHSSVCTNAVG 509 Score = 124 bits (311), Expect = 7e-28 Identities = 78/242 (32%), Positives = 107/242 (44%), Gaps = 37/242 (15%) Query: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739 +Y + + G CN + S + + + C CK N G+ C+ C L F Sbjct: 274 YYAISDFAVGGRCKCNGHASECMKNEF----DKLVCNCKHNTYGVDCEKC------LPFF 323 Query: 740 ND-----------VGCEPCQCNLHGSVNKF------CNPHSGQC-ECKKEAKGLQCDTCR 781 ND C PC CN F H G C C+ G C+ CR Sbjct: 324 NDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCR 383 Query: 782 ENFYGLDVTN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNN 840 ENF+ L C +C C GSL T C++ G+C CKP V G +C++C G L + Sbjct: 384 ENFFRLGNNEACSSCHCSPVGSL-STQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAG 441 Query: 841 SFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC 900 C PC+CD +G+I+ CN TG+C CK V G C +C+P +NL N + C C Sbjct: 442 ---CRPCSCDPSGSIDE---CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPC 495 Query: 901 EC 902 C Sbjct: 496 FC 497 Score = 119 bits (297), Expect = 3e-26 Identities = 87/281 (30%), Positives = 118/281 (41%), Gaps = 40/281 (14%) Query: 796 DCDTAGSLPGTVCNAK-TGQCICKPNVEGRQCNKCLEGNFYLRQNNSF----LCLPCNCD 850 D A + PG A C C G+ C CL G Y R+ + C+ C C+ Sbjct: 670 DVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSG--YRRETPNLGPYSPCVLCACN 727 Query: 851 KTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRY-NLTIDNFQHCQMCEC---DSLG 906 S C+ TG C C+ G C +C Y + T CQ C C S Sbjct: 728 -----GHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCA 782 Query: 907 TLPGT---ICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATG----CLPCSCHTTGAV 959 +P T +C C G+RC C G++ P G C C C Sbjct: 783 VVPKTKEVVCTN------CPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDP 836 Query: 960 NHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP----QTGRCQPCNCHLSGALNE- 1012 N + CN LTG+C+ + AG CD+CKD +FG +P +C+ CNC+L G + + Sbjct: 837 NAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFG-NPLAPNPADKCKACNCNLYGTMKQQ 895 Query: 1013 -TCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052 +C+ VTGQC C VTG C AC P +L GC + Sbjct: 896 SSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQ--GCER 934 Score = 117 bits (294), Expect = 7e-26 Identities = 72/240 (30%), Positives = 112/240 (46%), Gaps = 42/240 (17%) Query: 759 CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNC---------KACDCDTAGSLPGTVCN 809 CN H+ +C K E L C+ C+ N YG+D C + ++A CN Sbjct: 288 CNGHASEC-MKNEFDKLVCN-CKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345 Query: 810 AKTGQCI-----------------CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852 ++ +C C+ N +G C +C E F L N + C C+C Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEA--CSSCHCSPV 403 Query: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912 G++ S C+ S G+C CK GV G +C++C+P ++LT C+ C CD G++ Sbjct: 404 GSL--STQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAG---CRPCSCDPSGSIDE-- 455 Query: 913 CDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCV 971 C+ +G+C+C N +G C +C+PGF+ + N GC PC C +V C + G V Sbjct: 456 CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSV---CTNAVGYSV 512 Score = 102 bits (254), Expect = 3e-21 Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 23/198 (11%) Query: 868 CPCKLGVTGLRCNQCEPHRYN-----LTIDNFQHCQMCECDSLGTLPGTICDPI------ 916 C CK G+ C +C P + T ++ C C+C+ G DP Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN--GRSQECYFDPELYRSTG 362 Query: 917 -SGQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQD 974 G C C N G C +C+ F+ GN C C C G+++ C+S G+C C+ Sbjct: 363 HGGHCTNCQDNTDGAHCERCRENFF-RLGNNEACSSCHCSPVGSLSTQCDSY-GRCSCKP 420 Query: 975 ASIAGQRCDQCKDHYFGFDPQT-GRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033 + G +CD+C+ GF T C+PC+C SG+++E C++ TG+C CK V G C+ Sbjct: 421 G-VMGDKCDRCQP---GFHSLTEAGCRPCSCDPSGSIDE-CNIETGRCVCKDNVEGFNCE 475 Query: 1034 ACVPSASHLDVNNLLGCS 1051 C P +L+ +N GC+ Sbjct: 476 RCKPGFFNLESSNPRGCT 493 Score = 69.3 bits (168), Expect = 3e-11 Identities = 46/148 (31%), Positives = 62/148 (41%), Gaps = 16/148 (10%) Query: 920 CLCVPNRQGRRCNQCQPGFYISPG------NATGCLPCSCHTTGAVNHICNSLT------ 967 C C N G C +C P F P +A+ CLPC C+ + L Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364 Query: 968 GQCV-CQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQF 1026 G C CQD + G C++C++++F C C+C G+L+ C G+C CK Sbjct: 365 GHCTNCQD-NTDGAHCERCRENFFRLGNNEA-CSSCHCSPVGSLSTQCDSY-GRCSCKPG 421 Query: 1027 VTGSKCDACVPSASHLDVNNLLGCSKTP 1054 V G KCD C P L CS P Sbjct: 422 VMGDKCDRCQPGFHSLTEAGCRPCSCDP 449 Score = 36.6 bits (83), Expect = 0.19 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 9/67 (13%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 C G D C+ + RC+C EG +C+RC P F + C PC C Sbjct: 447 CDPSGSIDECNIETG--RCVCKDN--VEGFNCERCKP-----GFFNLESSNPRGCTPCFC 497 Query: 578 NSHSKSC 584 HS C Sbjct: 498 FGHSSVC 504 >gi|110611156 laminin, gamma 3 precursor [Homo sapiens] Length = 1575 Score = 231 bits (590), Expect = 3e-60 Identities = 145/433 (33%), Positives = 210/433 (48%), Gaps = 47/433 (10%) Query: 340 HPLSFVND---NDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTE 396 H S++ D D T W S Q V I++ L Y++ Y+ ++F + +P Sbjct: 86 HNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKA-YEITYVRLKFHTSRPES 144 Query: 397 IRIQRKKENSLDWEDWQYFARNCGAFGMKNNGDLEKPDSVNCL-----QLSNFTPYSRGN 451 I ++ WE +Q+++ +C + G +P + + S+ +P S GN Sbjct: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGN 204 Query: 452 VTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQI-----RFHFHGQYYTTETAVNLRHRY 506 V FS L RP NF +P LQE+V +T++ R + G + V L+ Y Sbjct: 205 VAFSTLEG----RPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKV-LQSYY 259 Query: 507 YAVDEITISGRCQCHGHADNC--DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQG 564 YAV + ++ GRC+C+GHA C D Q C C T G C+RCLP + D+P+ +G Sbjct: 260 YAVSDFSVGGRCKCNGHASECGPDVAGQ-LACRCQHN--TTGTDCERCLPFFQDRPWARG 316 Query: 565 DQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR--GGGGVCDDCEHNTTGRNCELCKD 622 A C PC C+ S+ C F E FR G GG C C +T G +CE C++ Sbjct: 317 TAEAAHECLPCNCSGRSEEC-------TFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE 369 Query: 623 YFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN 682 F+ DP C+PCDC + G+ + + CD G C CK V+G +C++C GF++ Sbjct: 370 NFYHW---DPRM--PCQPCDCQSAGSLH--LQCDDT-GTCACKPTVTGWKCDRCLPGFHS 421 Query: 683 LQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDV 742 L E GC PC CN +G++D TC SG+C CK NV G CD C G L+ N Sbjct: 422 LSE---GGCRPCTCNPAGSLD---TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475 Query: 743 GCEPCQCNLHGSV 755 GC C C H V Sbjct: 476 GCSSCFCYGHSKV 488 Score = 186 bits (471), Expect = 2e-46 Identities = 110/337 (32%), Positives = 150/337 (44%), Gaps = 37/337 (10%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 C C+ H CD + C+CS TEG C+RCLP + PF A +C+PC C Sbjct: 707 CTCNQHG-TCDPNTGI--CVCSHH--TEGPSCERCLPGFYGNPFAG----QADDCQPCPC 757 Query: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI-- 635 S S + VC C GR CE+C D FF DP + Sbjct: 758 PGQSACTTIPESREV-----------VCTHCPPGQRGRRCEVCDDGFF----GDPLGLFG 802 Query: 636 --DVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDG 690 C C C N CD + G C C + +G C CQ GFY L D Sbjct: 803 HPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADK 862 Query: 691 CSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750 C PC+C+ G+V + C +GQC C +V C C GF L+ GC C+C+ Sbjct: 863 CMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGR--GCRSCKCH 920 Query: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810 GS C+P +GQC C+ G CD C+ F+G + C+AC C G+ C+ Sbjct: 921 PLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGA-ASAQCH- 978 Query: 811 KTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847 + G C+C+P EG +C++C NF+L + + C C Sbjct: 979 ENGTCVCRPGFEGYKCDRC-HDNFFLTADGTH-CQQC 1013 Score = 182 bits (463), Expect = 2e-45 Identities = 109/338 (32%), Positives = 156/338 (46%), Gaps = 30/338 (8%) Query: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECKK 770 C C G C+ C G+K R G C PC CN HG+ C+P++G C C Sbjct: 673 CSCPTGYTGQFCESCAPGYK--REMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSH 726 Query: 771 EAKGLQCDTCRENFYGL----DVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQ 825 +G C+ C FYG +C+ C C + T+ ++ C C P GR+ Sbjct: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACT-TIPESREVVCTHCPPGQRGRR 785 Query: 826 CNKCLEGNFYLRQNNSFLCLPCN-CDKTGTINGSLL--CNKSTGQC-PCKLGVTGLRCNQ 881 C C +G F PC+ C +G ++ + + C+ +G C C TG C Sbjct: 786 CEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845 Query: 882 CEPHRYN--LTIDNFQHCQMCECDSLGTLPGTI-CDPISGQCLCVPNRQGRRCNQCQPGF 938 C+ Y L C C C G++ + CDP++GQC C+P+ R C++C PGF Sbjct: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905 Query: 939 Y-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTG 997 + + PG GC C CH G+ C+ TGQC C+ + GQ CD+C+ +FGF + Sbjct: 906 FDLQPGR--GCRSCKCHPLGSQEDQCHPKTGQCTCRPG-VTGQACDRCQLGFFGFSIKG- 961 Query: 998 RCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035 C+ C C GA + CH G C C+ G KCD C Sbjct: 962 -CRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRC 997 Score = 176 bits (446), Expect = 2e-43 Identities = 117/392 (29%), Positives = 174/392 (44%), Gaps = 42/392 (10%) Query: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDG----CSPCNCNTSGTVDGDITCHQNSGQCKC 717 C+C +G+ C C G+ +E+ G C PC CN GT C N+G C C Sbjct: 673 CSCPTGYTGQFCESCAPGYK--REMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 724 Query: 718 KANVIGLRCDHCNFGF---KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAK 773 + G C+ C GF F +D C+PC C + C C + Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADD--CQPCPCPGQSACTTIPESREVVCTHCPPGQR 782 Query: 774 GLQCDTCRENFYGLDV------TNCKACDCDTAGSL-PGTV--CNAKTGQCI-CKPNVEG 823 G +C+ C + F+G + C C C +G++ P V C+ +G C+ C N G Sbjct: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQC--SGNVDPNAVGNCDPLSGHCLRCLHNTTG 840 Query: 824 RQCNKCLEGNFY---LRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN 880 C C EG FY L + C+PC+C G+++ + C+ TGQC C VT C+ Sbjct: 841 DHCEHCQEG-FYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS 899 Query: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940 +C P ++L + C+ C+C LG+ C P +GQC C P G+ C++CQ GF+ Sbjct: 900 RCYPGFFDLQPG--RGCRSCKCHPLGSQEDQ-CHPKTGQCTCRPGVTGQACDRCQLGFF- 955 Query: 941 SPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQ 1000 + GC C C GA + C+ G CVC+ G +CD+C D++F CQ Sbjct: 956 -GFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPG-FEGYKCDRCHDNFF-LTADGTHCQ 1011 Query: 1001 PCNCHLSGALNETCHLVTGQCFCKQFVTGSKC 1032 C + E L + ++ GS C Sbjct: 1012 QCPSCYALVKEEAAKLKARLTLTEGWLQGSDC 1043 Score = 173 bits (439), Expect = 1e-42 Identities = 116/372 (31%), Positives = 161/372 (43%), Gaps = 54/372 (14%) Query: 608 CEHNTTGRNCELCKDYFFRQVG-ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKR 666 C TG+ CE C + R++ P A C PC C+ GT CD G C C Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQGGPYAS--CVPCTCNQHGT------CDPNTGICVCSH 726 Query: 667 HVSGRQCNQCQNGFY-NLQELDPDGCSPCNCN-----TSGTVDGDITCHQNSGQCKCKAN 720 H G C +C GFY N D C PC C T+ ++ C C Sbjct: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTH------CPPG 780 Query: 721 VIGLRCDHCNFGFKFLRSFNDV--------GCEPCQCNLHGSVNKF--CNPHSGQC-ECK 769 G RC+ C+ GF F D C CQC+ + N C+P SG C C Sbjct: 781 QRGRRCEVCDDGF-----FGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCL 835 Query: 770 KEAKGLQCDTCRENFYGLDVT-----NCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEG 823 G C+ C+E FYG + C C C GS+ + C+ TGQC C P+V Sbjct: 836 HNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTA 895 Query: 824 RQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCE 883 R C++C G F L+ C C C G+ C+ TGQC C+ GVTG C++C+ Sbjct: 896 RDCSRCYPGFFDLQPGRG--CRSCKCHPLGSQEDQ--CHPKTGQCTCRPGVTGQACDRCQ 951 Query: 884 PHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPG 943 + +I C+ C C LG + +G C+C P +G +C++C F+++ Sbjct: 952 LGFFGFSIKG---CRACRCSPLGAASAQCHE--NGTCVCRPGFEGYKCDRCHDNFFLT-A 1005 Query: 944 NATGCLPC-SCH 954 + T C C SC+ Sbjct: 1006 DGTHCQQCPSCY 1017 Score = 165 bits (418), Expect = 3e-40 Identities = 101/309 (32%), Positives = 139/309 (44%), Gaps = 32/309 (10%) Query: 766 CECKKEAKGLQCDTC-----RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPN 820 C C G C++C RE G +C C C+ G+ C+ TG C+C + Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-----CDPNTGICVCSHH 727 Query: 821 VEGRQCNKCLEGNFYLRQNNSFL-----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVT 875 EG C +CL G FY N F C PC C ++ ++ C G Sbjct: 728 TEGPSCERCLPG-FY---GNPFAGQADDCQPCPCPGQSACT-TIPESREVVCTHCPPGQR 782 Query: 876 GLRCNQCEPHRYNLTIDNFQHCQMC-ECDSLGTL-PGTI--CDPISGQCL-CVPNRQGRR 930 G RC C+ + + F H Q C +C G + P + CDP+SG CL C+ N G Sbjct: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842 Query: 931 CNQCQPGFY---ISPGNATGCLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQC 985 C CQ GFY ++P A C+PCSCH G+V+ C+ +TGQC C + + C +C Sbjct: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLP-HVTARDCSRC 901 Query: 986 KDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVN 1045 +F P G C+ C CH G+ + CH TGQC C+ VTG CD C + Sbjct: 902 YPGFFDLQPGRG-CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIK 960 Query: 1046 NLLGCSKTP 1054 C +P Sbjct: 961 GCRACRCSP 969 Score = 124 bits (311), Expect = 7e-28 Identities = 77/239 (32%), Positives = 111/239 (46%), Gaps = 25/239 (10%) Query: 677 QNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFK-- 734 Q+ +Y + + G C CN + G Q + C+C+ N G C+ C F+ Sbjct: 256 QSYYYAVSDFSVGG--RCKCNGHASECGPDVAGQLA--CRCQHNTTGTDCERCLPFFQDR 311 Query: 735 -FLRSFNDVG--CEPCQCNLHGSVNKF------CNPHSGQCE-CKKEAKGLQCDTCRENF 784 + R + C PC C+ F H G+C C+ G C+ C+ENF Sbjct: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371 Query: 785 YGLDVTN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL 843 Y D C+ CDC +AGSL C+ TG C CKP V G +C++CL G L + Sbjct: 372 YHWDPRMPCQPCDCQSAGSLH-LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGG--- 426 Query: 844 CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902 C PC C+ G+++ C+ +G+CPCK V G C++C P +NL N C C C Sbjct: 427 CRPCTCNPAGSLD---TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482 Score = 115 bits (289), Expect = 3e-25 Identities = 68/221 (30%), Positives = 102/221 (46%), Gaps = 21/221 (9%) Query: 641 CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDG-----CSPCN 695 C C+ + G + Q+ C C+ + +G C +C F + C PCN Sbjct: 271 CKCNGHASECGPDVAGQLA--CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328 Query: 696 CNTSG---TVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQ 748 C+ T D ++ T H G+C C+ + G C+ C F + C+PC Sbjct: 329 CSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENFYHWDP--RMPCQPCD 384 Query: 749 CNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808 C GS++ C+ +G C CK G +CD C F+ L C+ C C+ AGSL C Sbjct: 385 CQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD--TC 441 Query: 809 NAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849 + ++G+C CK NVEG C++C G F L+ +N C C C Sbjct: 442 DPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482 Score = 109 bits (272), Expect = 2e-23 Identities = 73/228 (32%), Positives = 107/228 (46%), Gaps = 35/228 (15%) Query: 747 CQCNLHGSVNKFCNPH-SGQ--CECKKEAKGLQCDTCRENFYGLD--------VTNCKAC 795 C+CN H S C P +GQ C C+ G C+ C F C C Sbjct: 271 CKCNGHASE---CGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327 Query: 796 DCDTAGSLPGTVCNAKT-------GQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847 +C +G + + G+C C+ + G C +C E NFY + C PC Sbjct: 328 NC--SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE-NFY-HWDPRMPCQPC 383 Query: 848 NCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT 907 +C G+++ L C+ TG C CK VTG +C++C P ++L+ C+ C C+ G+ Sbjct: 384 DCQSAGSLH--LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGG---CRPCTCNPAGS 437 Query: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCH 954 L CDP SG+C C N +G C++C+PG F + P N GC C C+ Sbjct: 438 L--DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483 Score = 95.5 bits (236), Expect = 4e-19 Identities = 59/195 (30%), Positives = 89/195 (45%), Gaps = 17/195 (8%) Query: 868 CPCKLGVTGLRCNQCEPHRYNL-----TIDNFQHCQMCECDSLG---TLPGTICDPIS-- 917 C C+ TG C +C P + T + C C C T + Sbjct: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349 Query: 918 GQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS 976 G+C C + G C +CQ FY C PC C + G+++ C+ TG C C+ + Sbjct: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRMP-CQPCDCQSAGSLHLQCDD-TGTCACKP-T 406 Query: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036 + G +CD+C + G C+PC C+ +G+L +TC +G+C CK+ V G+ CD C Sbjct: 407 VTGWKCDRCLPGFHSLSE--GGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCR 463 Query: 1037 PSASHLDVNNLLGCS 1051 P +L +N GCS Sbjct: 464 PGTFNLQPHNPAGCS 478 Score = 87.0 bits (214), Expect = 1e-16 Identities = 59/184 (32%), Positives = 86/184 (46%), Gaps = 23/184 (12%) Query: 887 YNLTIDNFQHCQMCECDSLGTLPGTICDP-ISGQ--CLCVPNRQGRRCNQCQPGFYISP- 942 Y + +F C+C+ + C P ++GQ C C N G C +C P F P Sbjct: 258 YYYAVSDFSVGGRCKCNG----HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPW 313 Query: 943 --GNATG---CLPCSCHTTGAVNHICNSLT------GQCV-CQDASIAGQRCDQCKDHYF 990 G A CLPC+C L G+C C+D + AG C++C+++++ Sbjct: 314 ARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHT-AGPHCERCQENFY 372 Query: 991 GFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050 +DP+ CQPC+C +G+L+ C TG C CK VTG KCD C+P L C Sbjct: 373 HWDPRMP-CQPCDCQSAGSLHLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPC 430 Query: 1051 SKTP 1054 + P Sbjct: 431 TCNP 434 Score = 39.7 bits (91), Expect = 0.023 Identities = 26/70 (37%), Positives = 30/70 (42%), Gaps = 13/70 (18%) Query: 518 CQCH--GHADNCDTTSQPYRCLCSQESFTEGLHCDRCLP-LYNDKPFRQGDQVYAFNCKP 574 C C+ G D CD S RC C + EG CDRC P +N +P C Sbjct: 430 CTCNPAGSLDTCDPRSG--RCPCKEN--VEGNLCDRCRPGTFNLQPHNPA------GCSS 479 Query: 575 CQCNSHSKSC 584 C C HSK C Sbjct: 480 CFCYGHSKVC 489 >gi|93204871 netrin 4 [Homo sapiens] Length = 628 Score = 197 bits (500), Expect = 9e-50 Identities = 131/429 (30%), Positives = 203/429 (47%), Gaps = 56/429 (13%) Query: 371 ISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNGD 429 I +DLE ++ ++I+ F SP+P + + R ++ W+ ++YFA NC A FG+++ D Sbjct: 117 IQLDLE-AEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLED--D 173 Query: 430 LEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF 489 + K ++ + S+ P + G V F L+P + Y+ +QE +K T +R Sbjct: 174 VVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYS-----AKVQEQLKITNLRVQL 228 Query: 490 HGQYYTTETAVNLRHR-----YYAVDEITISGRCQCHGHADNCDTTS--QPYR------- 535 + +L +YA+ + + G C C+GHAD C +P + Sbjct: 229 LKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHM 288 Query: 536 ----CLCSQESFTEGLHCDRCLPLYNDKPFRQGD-QVYAFN-CKPCQCNSHSKSCHYNIS 589 C+C T G HC C PLYND+P+ D + A N C+ C+CN H+ +CH++++ Sbjct: 289 VHGKCMCKHN--TAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVN 346 Query: 590 VDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGT- 648 V GGVCDDC+HNT G+ C+ CK F+R + SA D CKPC C VG+ Sbjct: 347 VWEASGNR---SGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSA 403 Query: 649 ---RNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705 N CD G C CK V+GR+C++C G++ + GC PC+C S Sbjct: 404 VLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDCAGS------ 454 Query: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765 C +G C I + +F +S EP + HSG+ Sbjct: 455 --CDPITGDCISSHTDIDWYHEVPDFRPVHNKS------EPA-WEWEDAQGFSALLHSGK 505 Query: 766 CECKKEAKG 774 CECK++ G Sbjct: 506 CECKEQTLG 514 Score = 87.0 bits (214), Expect = 1e-16 Identities = 60/188 (31%), Positives = 80/188 (42%), Gaps = 42/188 (22%) Query: 658 IGGQCNCKRHVSGRQCNQCQNGFYNLQELD--------PDGCSPCNCNTSGTVDGDITCH 709 + G+C CK + +G C C YN + + P+ C C CN G D TCH Sbjct: 289 VHGKCMCKHNTAGSHCQHCAP-LYNDRPWEAADGKTGAPNECRTCKCN--GHAD---TCH 342 Query: 710 -----------QNSGQCK-CKANVIGLRCDHCNFGF--KFLRSFNDV-GCEPCQCNLHGS 754 ++ G C C+ N G C C GF R F+ C+PC C+ GS Sbjct: 343 FDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGS 402 Query: 755 VN------KFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808 FC+P +G C CK G +CD C ++G C+ CDC AGS C Sbjct: 403 AVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC--AGS-----C 455 Query: 809 NAKTGQCI 816 + TG CI Sbjct: 456 DPITGDCI 463 Score = 85.1 bits (209), Expect = 5e-16 Identities = 68/223 (30%), Positives = 90/223 (40%), Gaps = 52/223 (23%) Query: 707 TCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC 766 T H G+C CK N G C HC +ND E G+ N+ C C Sbjct: 285 TFHMVHGKCMCKHNTAGSHCQHC------APLYNDRPWEAADGKT-GAPNE-CRT----C 332 Query: 767 ECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQC 826 +C A DTC DV +A +G+ G VC+ C+ N EG+ C Sbjct: 333 KCNGHA-----DTCH-----FDVNVWEA-----SGNRSGGVCDD------CQHNTEGQYC 371 Query: 827 NKCLEGNFYLRQNNSF----LCLPCNCDKTGTI----NGSLLCNKSTGQCPCKLGVTGLR 878 +C G FY F C PC+C G+ N C+ S G CPCK GV G R Sbjct: 372 QRCKPG-FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRR 430 Query: 879 CNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL 921 C++C + C+ C+C CDPI+G C+ Sbjct: 431 CDRCMVGYWGF---GDYGCRPCDC-------AGSCDPITGDCI 463 Score = 77.4 bits (189), Expect = 1e-13 Identities = 72/258 (27%), Positives = 101/258 (39%), Gaps = 46/258 (17%) Query: 804 PGTVCNAKTGQCICKPNVEGRQCNKC--LEGNFYLRQNNSFLCLPCNCDKTGTINGSL-L 860 PGT + G+C+CK N G C C L + + P C +T NG Sbjct: 283 PGTF-HMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNEC-RTCKCNGHADT 340 Query: 861 C-----------NKSTGQCP-CKLGVTGLRCNQCEPHRYNLTIDNFQH---CQMCECDSL 905 C N+S G C C+ G C +C+P Y F C+ C C + Sbjct: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400 Query: 906 GT--LPG---TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN 960 G+ LP T CDP +G C C P GRRC++C G++ GC PC C + Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW--GFGDYGCRPCDCAGS---- 454 Query: 961 HICNSLTGQCVCQDASIAGQRCDQCKDHYF---GFDPQTGRCQPCNCHLSGALNETCHLV 1017 C+ +TG C+ I D Y F P + +P A + L Sbjct: 455 --CDPITGDCISSHTDI---------DWYHEVPDFRPVHNKSEPA-WEWEDAQGFSALLH 502 Query: 1018 TGQCFCKQFVTGSKCDAC 1035 +G+C CK+ G+ C Sbjct: 503 SGKCECKEQTLGNAKAFC 520 Score = 59.3 bits (142), Expect = 3e-08 Identities = 45/155 (29%), Positives = 60/155 (38%), Gaps = 29/155 (18%) Query: 909 PGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNA----TG----CLPCSCHTTGAVN 960 PGT + G+C+C N G C C P + P A TG C C C+ Sbjct: 283 PGTF-HMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTC 341 Query: 961 HI--------CNSLTGQCVCQDASIAGQRCDQCKDHYF-----GFDPQTGRCQPCNCHLS 1007 H N G C + GQ C +CK ++ F C+PC+CH Sbjct: 342 HFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA-CKPCSCHPV 400 Query: 1008 GALNETCHLVT------GQCFCKQFVTGSKCDACV 1036 G+ + VT G C CK V G +CD C+ Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCM 435 Score = 33.1 bits (74), Expect = 2.1 Identities = 12/25 (48%), Positives = 14/25 (56%) Query: 1013 TCHLVTGQCFCKQFVTGSKCDACVP 1037 T H+V G+C CK GS C C P Sbjct: 285 TFHMVHGKCMCKHNTAGSHCQHCAP 309 >gi|148613884 netrin 1 [Homo sapiens] Length = 604 Score = 196 bits (497), Expect = 2e-49 Identities = 116/380 (30%), Positives = 186/380 (48%), Gaps = 30/380 (7%) Query: 317 RYCIPNDAGDTADNRVSRLNP----EAHPLSFVNDNDVG---TSWVSNVFTNITQLNQGV 369 RYC+ ++ G+ N +AHP +F+ D + T W S N Q V Sbjct: 76 RYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSE---NYLQFPHNV 132 Query: 370 TISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNG 428 T+++ L +++V Y+ +QF SP+P + I + + W +Q+++ C + + Sbjct: 133 TLTLSLGK-KFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRA 191 Query: 429 DLEKPDSVNCLQLSNFT---PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQI 485 + K + + + T P S G + FS L + RP ++F N+P LQ++V AT I Sbjct: 192 PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTL----DGRPSAHDFDNSPVLQDWVTATDI 247 Query: 486 R-----FHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ 540 R H G ++ + +YAV ++ + GRC+C+GHA C + +C Sbjct: 248 RVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARC-VRDRDDSLVCDC 306 Query: 541 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG 600 T G CDRC P + D+P+++ A C C CN H++ C +N+ + R Sbjct: 307 RHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG---RK 363 Query: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 GGVC +C HNT GR+C CK+ ++R +G + CK CDC VG + C+Q G Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKT--CNQTTG 421 Query: 661 QCNCKRHVSGRQCNQCQNGF 680 QC CK V+G CN+C G+ Sbjct: 422 QCPCKDGVTGITCNRCAKGY 441 Score = 84.7 bits (208), Expect = 6e-16 Identities = 56/174 (32%), Positives = 73/174 (41%), Gaps = 27/174 (15%) Query: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739 FY + +L G CN + + V +S C C+ N G CD C F + R + Sbjct: 273 FYAVSDLQVGGRCKCNGHAARCVRD----RDDSLVCDCRHNTAGPECDRCK-PFHYDRPW 327 Query: 740 NDVG------CEPCQCNLHGSVNKFC--------NPHSGQC-ECKKEAKGLQCDTCRENF 784 C C CNLH +F G C C+ G C C+E + Sbjct: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387 Query: 785 Y---GLDVTN---CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEG 832 Y G +T+ CKACDC G+ G CN TGQC CK V G CN+C +G Sbjct: 388 YRDMGKPITHRKACKACDCHPVGAA-GKTCNQTTGQCPCKDGVTGITCNRCAKG 440 Score = 80.9 bits (198), Expect = 9e-15 Identities = 50/163 (30%), Positives = 69/163 (42%), Gaps = 37/163 (22%) Query: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY--------GLDVTNCKACDCD 798 C+CN H + S C+C+ G +CD C+ Y + C AC+C+ Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344 Query: 799 T--------------AGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL- 843 +G G VC C+ N GR C+ C EG Y R + Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVC------LNCRHNTAGRHCHYCKEG--YYRDMGKPIT 396 Query: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQC 882 C C+C G + CN++TGQCPCK GVTG+ CN+C Sbjct: 397 HRKACKACDCHPVGAAGKT--CNQTTGQCPCKDGVTGITCNRC 437 Score = 73.6 bits (179), Expect = 1e-12 Identities = 49/192 (25%), Positives = 83/192 (43%), Gaps = 41/192 (21%) Query: 618 ELCKDYFFRQVGADPSAIDVCKPCDCD-----TVGTRNGSILCDQIGGQCNCKRHVSGRQ 672 EL +D +F V S + V C C+ V R+ S++CD C+ + +G + Sbjct: 266 ELARDSYFYAV----SDLQVGGRCKCNGHAARCVRDRDDSLVCD-------CRHNTAGPE 314 Query: 673 CNQCQNGFYN-----LQELDPDGCSPCNCNTSGTVDG------DITCHQNSGQC-KCKAN 720 C++C+ Y+ + + C CNCN ++ ++ G C C+ N Sbjct: 315 CDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHN 374 Query: 721 VIGLRCDHCNFGFKFLRSFNDVG--------CEPCQCNLHGSVNKFCNPHSGQCECKKEA 772 G C +C G+ + D+G C+ C C+ G+ K CN +GQC CK Sbjct: 375 TAGRHCHYCKEGY-----YRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGV 429 Query: 773 KGLQCDTCRENF 784 G+ C+ C + + Sbjct: 430 TGITCNRCAKGY 441 Score = 73.2 bits (178), Expect = 2e-12 Identities = 49/157 (31%), Positives = 69/157 (43%), Gaps = 19/157 (12%) Query: 920 CLCVPNRQGRRCNQCQPGFYISPGN------ATGCLPCSCHTTGA---VNHICNSLTGQ- 969 C C N G C++C+P Y P A C+ C+C+ N L+G+ Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363 Query: 970 ----CVCQDASIAGQRCDQCKDHYFGF--DPQTGR--CQPCNCHLSGALNETCHLVTGQC 1021 C+ + AG+ C CK+ Y+ P T R C+ C+CH GA +TC+ TGQC Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423 Query: 1022 FCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQP 1058 CK VTG C+ C + + C K P P Sbjct: 424 PCKDGVTGITCNRCAKGYQQ-SRSPIAPCIKIPVAPP 459 Score = 60.1 bits (144), Expect = 2e-08 Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 22/163 (13%) Query: 815 CICKPNVEGRQCNKCLEGNF-------YLRQNNSFLCLPCNCD------KTGTINGSLLC 861 C C+ N G +C++C ++ R+ N C+ CNC+ + L Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANE--CVACNCNLHARRCRFNMELYKLSG 361 Query: 862 NKSTGQC-PCKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPGTICDPIS 917 KS G C C+ G C+ C+ Y I + + C+ C+C +G G C+ + Sbjct: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAA-GKTCNQTT 420 Query: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGC--LPCSCHTTGA 958 GQC C G CN+C G+ S C +P + TT A Sbjct: 421 GQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAA 463 >gi|5453810 netrin 3 [Homo sapiens] Length = 580 Score = 163 bits (412), Expect = 1e-39 Identities = 97/321 (30%), Positives = 151/321 (47%), Gaps = 23/321 (7%) Query: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC----GAFGM 424 VT++V L +++ ++ ++F S P + + + +++ W +F+ +C G Sbjct: 105 VTLTVPLGKA-FELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPA 163 Query: 425 KNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484 NG C P G + FS+ P PG + ++P LQ++V AT Sbjct: 164 PANGPAGPGPEALCFPAPLAQPDGSGLLAFSMQDSSP---PGLD-LDSSPVLQDWVTATD 219 Query: 485 IRFHFH-----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCS 539 +R G E V YA ++ + GRC+C+GHA C +Q + +C Sbjct: 220 VRVVLTRPSTAGDPRDMEAVVPYS---YAATDLQVGGRCKCNGHASRCLLDTQGH-LICD 275 Query: 540 QESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR 599 TEG C RC P Y D+P+++ + C C CN H++ C +N+ + R Sbjct: 276 CRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSG---R 332 Query: 600 GGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIG 659 GGVC +C HNT GR+C C++ F+R G S C+ CDC VG + C+Q Sbjct: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKT--CNQTT 390 Query: 660 GQCNCKRHVSGRQCNQCQNGF 680 GQC CK V+G CN+C GF Sbjct: 391 GQCPCKDGVTGLTCNRCAPGF 411 Score = 85.5 bits (210), Expect = 4e-16 Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 26/176 (14%) Query: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634 C+CN H+ C + G + DC H T G +C CK ++ + +A Sbjct: 255 CKCNGHASRCLLDTQ------------GHLICDCRHGTEGPDCGRCKPFYCDRPWQRATA 302 Query: 635 ID--VCKPCDCDTVGTRNG------SILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--- 682 + C C C+ R + + GG C NC+ + +GR C+ C+ GFY Sbjct: 303 RESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPG 362 Query: 683 LQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRS 738 D C C+C+ G TC+Q +GQC CK V GL C+ C GF+ RS Sbjct: 363 RALSDRRACRACDCHPVGAAGK--TCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRS 416 Score = 77.4 bits (189), Expect = 1e-13 Identities = 52/165 (31%), Positives = 68/165 (41%), Gaps = 37/165 (22%) Query: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY---------GLDVTNCKACDC 797 C+CN H S C+C+ +G C C+ FY + C AC C Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSC 313 Query: 798 D--------------TAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF- 842 + +G G VC C+ N GR C+ C EG FY + Sbjct: 314 NGHARRCRFNMELYRLSGRRSGGVC------LNCRHNTAGRHCHYCREG-FYRDPGRALS 366 Query: 843 ---LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEP 884 C C+C G + CN++TGQCPCK GVTGL CN+C P Sbjct: 367 DRRACRACDCHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAP 409 Score = 75.1 bits (183), Expect = 5e-13 Identities = 58/191 (30%), Positives = 73/191 (38%), Gaps = 45/191 (23%) Query: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716 Q+GG+C C H S +C LD G C+C GT D G+CK Sbjct: 250 QVGGRCKCNGHAS-----RCL--------LDTQGHLICDCR-HGTEGPDC------GRCK 289 Query: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFC--------NPHSGQC-E 767 +C+ ++ + C C CN H +F G C Sbjct: 290 PF---------YCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLN 340 Query: 768 CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNV 821 C+ G C CRE FY D C+ACDC G+ G CN TGQC CK V Sbjct: 341 CRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAA-GKTCNQTTGQCPCKDGV 399 Query: 822 EGRQCNKCLEG 832 G CN+C G Sbjct: 400 TGLTCNRCAPG 410 Score = 74.7 bits (182), Expect = 6e-13 Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 35/184 (19%) Query: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNAT------GCL 949 H C D+ G L ICD C +G C +C+P + P CL Sbjct: 260 HASRCLLDTQGHL---ICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESHACL 309 Query: 950 PCSCHTTGA---VNHICNSLTGQ-----CVCQDASIAGQRCDQCKDHYFGFDPQTGR--- 998 CSC+ N L+G+ C+ + AG+ C C++ GF GR Sbjct: 310 ACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCRE---GFYRDPGRALS 366 Query: 999 ----CQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTP 1054 C+ C+CH GA +TC+ TGQC CK VTG C+ C P + + C KTP Sbjct: 367 DRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQ-SRSPVAPCVKTP 425 Query: 1055 FQQP 1058 P Sbjct: 426 IPGP 429 Score = 62.8 bits (151), Expect = 3e-09 Identities = 39/144 (27%), Positives = 56/144 (38%), Gaps = 27/144 (18%) Query: 662 CNCKRHVSGRQCNQCQNGFY------NLQELDPDGCSPCNCNTSGTVDG------DITCH 709 C+C+ G C +C+ FY + C C+CN ++ Sbjct: 274 CDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332 Query: 710 QNSGQC-KCKANVIGLRCDHCNFGFKFLRSFNDVG--------CEPCQCNLHGSVNKFCN 760 ++ G C C+ N G C +C GF + D G C C C+ G+ K CN Sbjct: 333 RSGGVCLNCRHNTAGRHCHYCREGF-----YRDPGRALSDRRACRACDCHPVGAAGKTCN 387 Query: 761 PHSGQCECKKEAKGLQCDTCRENF 784 +GQC CK GL C+ C F Sbjct: 388 QTTGQCPCKDGVTGLTCNRCAPGF 411 >gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] Length = 639 Score = 162 bits (411), Expect = 2e-39 Identities = 105/314 (33%), Positives = 154/314 (49%), Gaps = 24/314 (7%) Query: 795 CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGT 854 C+C GSL CN TGQC C+P +G C C EG FYL S LC PC+C G Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEG-FYLNY-TSGLCQPCDCSPHGA 298 Query: 855 INGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICD 914 + S+ CN S+G+C CK+GV G C++C+ Y + + C C+C++ CD Sbjct: 299 L--SIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNG---CLPCQCNN----RSASCD 348 Query: 915 PISGQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCH---TTGAVNHICNSLTGQC 970 ++G CL C N +G C +C+ GFY SP CL C C +TG+ + + L +C Sbjct: 349 ALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPEC 408 Query: 971 -VCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALN-ETCHLVTGQCF-CKQFV 1027 C+D I G C++C++ Y+ FD +CQ C+ H+ + C +G+C C Sbjct: 409 DQCKDGYI-GPNCNKCENGYYNFDSICRKCQ-CHGHVDPVKTPKICKPESGECINCLHNT 466 Query: 1028 TGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLTY 1087 TG C+ C+ H D+ C K P P G S +L+ S P T Sbjct: 467 TGFWCENCLEGYVH-DLEG--NCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTP 523 Query: 1088 SLLRDGFEIYTTED 1101 + L+ F + T+E+ Sbjct: 524 TTLQTIFSVSTSEN 537 Score = 152 bits (384), Expect = 2e-36 Identities = 87/253 (34%), Positives = 131/253 (51%), Gaps = 23/253 (9%) Query: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753 CNC+ G+++ + C+Q +GQC+C+ GL C+ C GF ++ C+PC C+ HG Sbjct: 241 CNCSVVGSLNVN-RCNQTTGQCECRPGYQGLHCETCKEGFYL--NYTSGLCQPCDCSPHG 297 Query: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813 +++ CN SG+C+CK G CD C++ +YG C C C+ + C+A TG Sbjct: 298 ALSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSA----SCDALTG 352 Query: 814 QCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK-TGTINGSLLCNKSTGQC-PC 870 C+ C+ N +G C +C EG FY + + CL C C T T + S+ ++ +C C Sbjct: 353 ACLNCQENSKGNHCEECKEG-FYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQC 411 Query: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC----DSLGTLPGTICDPISGQCL-CVPN 925 K G G CN+CE YN C+ C+C D + T IC P SG+C+ C+ N Sbjct: 412 KDGYIGPNCNKCENGYYNFD----SICRKCQCHGHVDPVKT--PKICKPESGECINCLHN 465 Query: 926 RQGRRCNQCQPGF 938 G C C G+ Sbjct: 466 TTGFWCENCLEGY 478 Score = 134 bits (338), Expect = 5e-31 Identities = 89/285 (31%), Positives = 126/285 (44%), Gaps = 31/285 (10%) Query: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667 CE N + L + +V A+ C+C VG+ N + C+Q GQC C+ Sbjct: 211 CESNLKSKYLPLTQPVMNLRVS---EAVKTEYVCNCSVVGSLNVN-RCNQTTGQCECRPG 266 Query: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727 G C C+ GFY C PC+C+ G + I C+ +SG+C+CK VIG CD Sbjct: 267 YQGLHCETCKEGFY--LNYTSGLCQPCDCSPHGAL--SIPCN-SSGKCQCKVGVIGSICD 321 Query: 728 HCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY- 785 C G+ F+ GC PCQCN + + C+ +G C C++ +KG C+ C+E FY Sbjct: 322 RCQDGY---YGFSKNGCLPCQCN---NRSASCDALTGACLNCQENSKGNHCEECKEGFYQ 375 Query: 786 GLDVT-NCKACDCDTAGSLPGTVCNAKTGQC-----ICKPNVEGRQCNKCLEGNFYLRQN 839 D T C C C S C+ K+ + CK G CNKC G + N Sbjct: 376 SPDATKECLRCPCSAVTSTGS--CSIKSSELEPECDQCKDGYIGPNCNKCENGYY----N 429 Query: 840 NSFLCLPCNC-DKTGTINGSLLCNKSTGQC-PCKLGVTGLRCNQC 882 +C C C + +C +G+C C TG C C Sbjct: 430 FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENC 474 Score = 127 bits (318), Expect = 1e-28 Identities = 84/256 (32%), Positives = 127/256 (49%), Gaps = 31/256 (12%) Query: 747 CQCNLHGSVN-KFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN--CKACDCDTAGSL 803 C C++ GS+N CN +GQCEC+ +GL C+TC+E FY L+ T+ C+ CDC G+L Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY-LNYTSGLCQPCDCSPHGAL 299 Query: 804 PGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK 863 CN+ +G+C CK V G C++C +G + +N CLPC C+ N S C+ Sbjct: 300 -SIPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSKNG---CLPCQCN-----NRSASCDA 349 Query: 864 STGQC-PCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI---CDPISGQ 919 TG C C+ G C +C+ Y + D + C C C ++ T G+ + + Sbjct: 350 LTGACLNCQENSKGNHCEECKEGFYQ-SPDATKECLRCPCSAV-TSTGSCSIKSSELEPE 407 Query: 920 C-LCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN-----HICNSLTGQCVCQ 973 C C G CN+C+ G+Y + C C CH G V+ IC +G+C+ Sbjct: 408 CDQCKDGYIGPNCNKCENGYY---NFDSICRKCQCH--GHVDPVKTPKICKPESGECINC 462 Query: 974 DASIAGQRCDQCKDHY 989 + G C+ C + Y Sbjct: 463 LHNTTGFWCENCLEGY 478 Score = 112 bits (280), Expect = 3e-24 Identities = 76/247 (30%), Positives = 109/247 (44%), Gaps = 29/247 (11%) Query: 603 GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC 662 G C+ C G +CE CK+ F+ + +C+PCDC G SI C+ G+C Sbjct: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTS-----GLCQPCDCSPHGAL--SIPCNS-SGKC 309 Query: 663 NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANV 721 CK V G C++CQ+G+Y + +GC PC CN +C +G C C+ N Sbjct: 310 QCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRSA-----SCDALTGACLNCQENS 361 Query: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCE-----CKKEAKGLQ 776 G C+ C GF + C C C+ S C+ S + E CK G Sbjct: 362 KGNHCEECKEGF-YQSPDATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPN 419 Query: 777 CDTCRENFYGLDVTNCKACDCDTAGSLPGT--VCNAKTGQCI-CKPNVEGRQCNKCLEGN 833 C+ C +Y D + C+ C C T +C ++G+CI C N G C CLEG Sbjct: 420 CNKCENGYYNFD-SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478 Query: 834 FYLRQNN 840 + + N Sbjct: 479 VHDLEGN 485 Score = 100 bits (250), Expect = 8e-21 Identities = 50/138 (36%), Positives = 75/138 (54%), Gaps = 9/138 (6%) Query: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGA 958 +C C +G+L C+ +GQC C P QG C C+ GFY++ + C PC C GA Sbjct: 240 VCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL-CQPCDCSPHGA 298 Query: 959 VNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVT 1018 ++ CNS +G+C C+ + G CD+C+D Y+GF C PC C+ A +C +T Sbjct: 299 LSIPCNS-SGKCQCK-VGVIGSICDRCQDGYYGF--SKNGCLPCQCNNRSA---SCDALT 351 Query: 1019 GQCF-CKQFVTGSKCDAC 1035 G C C++ G+ C+ C Sbjct: 352 GACLNCQENSKGNHCEEC 369 Score = 98.2 bits (243), Expect = 5e-20 Identities = 69/225 (30%), Positives = 94/225 (41%), Gaps = 46/225 (20%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN---CKP 574 C C H + +C C G CDRC D Y F+ C P Sbjct: 291 CDCSPHGALSIPCNSSGKCQCKVGVI--GSICDRCQ-----------DGYYGFSKNGCLP 337 Query: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634 CQCN+ S SC G C +C+ N+ G +CE CK+ F++ P A Sbjct: 338 CQCNNRSASCDALT--------------GACLNCQENSKGNHCEECKEGFYQ----SPDA 379 Query: 635 IDVCKPCDCDTV-GTRNGSILCDQIGGQCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCS 692 C C C V T + SI ++ +C+ CK G CN+C+NG+YN + C Sbjct: 380 TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI----CR 435 Query: 693 PCNCNTSGTVDGDIT---CHQNSGQC-KCKANVIGLRCDHCNFGF 733 C C+ G VD T C SG+C C N G C++C G+ Sbjct: 436 KCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478 Score = 96.7 bits (239), Expect = 2e-19 Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 55/253 (21%) Query: 545 EGLHCDRCLPLYNDKPFRQGDQVYAFN--CKPCQCNSHSKSCHYNISVDPFPFEHFRGGG 602 +GLHC+ C ++G + + C+PC C+ H +S+ Sbjct: 268 QGLHCETC---------KEGFYLNYTSGLCQPCDCSPHGA-----LSIP-------CNSS 306 Query: 603 GVCDDCEHNTTGRNCELCKD--YFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 G C C+ G C+ C+D Y F + G C PC C+ N S CD + G Sbjct: 307 GKC-QCKVGVIGSICDRCQDGYYGFSKNG--------CLPCQCN-----NRSASCDALTG 352 Query: 661 QC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCN-TSGTVDGDITCHQNSGQC-KC 717 C NC+ + G C +C+ GFY + + C C C+ + T I + +C +C Sbjct: 353 ACLNCQENSKGNHCEECKEGFYQSPDATKE-CLRCPCSAVTSTGSCSIKSSELEPECDQC 411 Query: 718 KANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVN-----KFCNPHSGQC-ECKKE 771 K IG C+ C G+ +F+ + C CQC HG V+ K C P SG+C C Sbjct: 412 KDGYIGPNCNKCENGY---YNFDSI-CRKCQC--HGHVDPVKTPKICKPESGECINCLHN 465 Query: 772 AKGLQCDTCRENF 784 G C+ C E + Sbjct: 466 TTGFWCENCLEGY 478 Score = 33.1 bits (74), Expect = 2.1 Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 15/59 (25%) Query: 506 YYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQES--------FTEGLHCDRCLPLY 556 YY D +I +CQCHGH D T +C ES T G C+ CL Y Sbjct: 427 YYNFD--SICRKCQCHGHVDPVKTPK-----ICKPESGECINCLHNTTGFWCENCLEGY 478 >gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] Length = 1044 Score = 155 bits (392), Expect = 3e-37 Identities = 155/573 (27%), Positives = 206/573 (35%), Gaps = 118/573 (20%) Query: 515 SGRCQCHGHADNCDTTSQPYRC-------LCSQESFTEGLHCDRCL---PLYNDKPFRQG 564 S C CH + C T+ C C + EGLH C P D Sbjct: 315 SQHCDCH-NGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCH 373 Query: 565 DQVYAFNCKPCQCNSH-SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDY 623 A C+P H ++SC D G C H+ TG C C Sbjct: 374 PVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADC----HSITG-GCT-CAPG 427 Query: 624 FFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYN 682 F +V A A P +C ++ + N C + G C CK G C C +G + Sbjct: 428 FMGEVCAVSCAAGTYGP-NCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG 486 Query: 683 LQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD-HCNFGFKFLRSFND 741 L NCN S T C G C C +G C+ C G +F Sbjct: 487 L-----------NCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDG-----TFGL 530 Query: 742 VGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCD-TCRENFYGLDVTNCK-ACDCDT 799 E C C+ C+P +G C C G++CD TC +G NC +C C+ Sbjct: 531 NCSEHCDCSHADG----CDPVTGHCCCLAGWTGIRCDSTCPPGRWG---PNCSVSCSCEN 583 Query: 800 AGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSL 859 GS C+ + G C C P G C + FY PC ++ S Sbjct: 584 GGS-----CSPEDGSCECAPGFRGPLCQRICPPGFY----GHGCAQPCPL----CVHSSR 630 Query: 860 LCNKSTGQCPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHC-QMCECDSLGTLPGTICDPIS 917 C+ +G C C G +G CNQ C + Q C Q+C C + GT C PI Sbjct: 631 PCHHISGICECLPGFSGALCNQVCAGGYFG------QDCAQLCSCANNGT-----CSPID 679 Query: 918 GQCLCVPNRQGRRCNQ-CQPGFY-------ISPGNATGCLP--CSCHTTGAVNHI----- 962 G C C P G+ C+Q C PGF+ S N C +CH T + Sbjct: 680 GSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQR 739 Query: 963 ---------------------CNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQ 1000 C+ ++G+C C+ GQ C+Q C FG+ Q Q Sbjct: 740 CPAAFFGKDCGRVCQCQNGASCDHISGKCTCR-TGFTGQHCEQRCAPGTFGYGCQ----Q 794 Query: 1001 PCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033 C C N TC VTG C+C G +CD Sbjct: 795 LCEC----MNNSTCDHVTGTCYCSPGFKGIRCD 823 Score = 148 bits (373), Expect = 5e-35 Identities = 160/567 (28%), Positives = 205/567 (36%), Gaps = 143/567 (25%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 C CH H CD + C T G DRC + PF + F QC Sbjct: 275 CPCH-HGGQCDHVTGQCHC-------TAGYMGDRC---QEECPFGS----FGF-----QC 314 Query: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCE--LCKDYFFRQVGADPSAI 635 + H CH P G C+ CE G C+ LC + G Sbjct: 315 SQHC-DCHNGGQCSPTT--------GACE-CEPGYKGPRCQERLCPE------GLHGPGC 358 Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCS-P 693 + PCD D +I C + G C C+ SG CN+ C G+Y DGC P Sbjct: 359 TLPCPCDADN------TISCHPVTGACTCQPGWSGHHCNESCPVGYYG------DGCQLP 406 Query: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD-HCNFGFKFLRSFNDVGCEPCQCNLH 752 C C CH +G C C +G C C G ++ C CN Sbjct: 407 CTCQNGAD------CHSITGGCTCAPGFMGEVCAVSCAAG-----TYGPNCSSICSCNNG 455 Query: 753 GSVNKFCNPHSGQCECKKEAKGLQCDT-CRENFYGLDVTNC-KACDCDTAGSLPGTVCNA 810 G+ C+P G C CK+ +GL C C +GL NC ++C C G C+ Sbjct: 456 GT----CSPVDGSCTCKEGWQGLDCTLPCPSGTWGL---NCNESCTCAN-----GAACSP 503 Query: 811 KTGQCICKPNVEGRQCN-KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP 869 G C C P G C C +G F L + C+C C+ TG C Sbjct: 504 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEH-----CDCSHADG------CDPVTGHCC 552 Query: 870 CKLGVTGLRCNQ-CEPHRY------NLTIDNFQHCQ----MCECDS--LGTLPGTICDP- 915 C G TG+RC+ C P R+ + + +N C CEC G L IC P Sbjct: 553 CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPG 612 Query: 916 ----------------------ISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSC 953 ISG C C+P G CNQ G Y A CSC Sbjct: 613 FYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ---LCSC 669 Query: 954 HTTGAVNHICNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQPCNCHLSGALNE 1012 A N C+ + G C C I G+ C Q C ++G C+CH +GA Sbjct: 670 ----ANNGTCSPIDGSCQCFPGWI-GKDCSQACPPGFWG----PACFHACSCH-NGA--- 716 Query: 1013 TCHLVTGQCFCKQFVTGSKCDACVPSA 1039 +C G C C TG C P+A Sbjct: 717 SCSAEDGACHCTPGWTGLFCTQRCPAA 743 Score = 128 bits (322), Expect = 4e-29 Identities = 126/439 (28%), Positives = 170/439 (38%), Gaps = 93/439 (21%) Query: 636 DVCKPCDCDTVGT--------RNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQEL 686 D CD D G +NG+ LC+ I G C C G +C + C G + Sbjct: 128 DCSSGCDSDHWGPHCSNRCQCQNGA-LCNPITGACVCAAGFRGWRCEELCAPGTHG---- 182 Query: 687 DPDGCS-PCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDH-CNFGFKFLRSFNDVGC 744 GC PC C + C +G+C C G+ C+ C G + C Sbjct: 183 --KGCQLPCQCRHGAS------CDPRAGECLCAPGYTGVYCEELCPPGS------HGAHC 228 Query: 745 E-PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKA-CDCDTAG 801 E C C G+ C+ +G+C C G C C +G NC C C G Sbjct: 229 ELRCPCQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTFG---QNCSQDCPCHHGG 281 Query: 802 SLPGTVCNAKTGQCICKPNVEGRQCNK-CLEGNFYLRQNNSFLCLP-CNCDKTGTINGSL 859 C+ TGQC C G +C + C G+F F C C+C G Sbjct: 282 Q-----CDHVTGQCHCTAGYMGDRCQEECPFGSF------GFQCSQHCDCHNGGQ----- 325 Query: 860 LCNKSTGQCPCKLGVTGLRCNQ--CEP--HRYNLTIDNFQHCQMCECDSLGTLPGTICDP 915 C+ +TG C C+ G G RC + C H T+ C CD+ T+ C P Sbjct: 326 -CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLP-------CPCDADNTIS---CHP 374 Query: 916 ISGQCLCVPNRQGRRCNQ-CQPGFYISPGNATGC-LPCSCHTTGAVNHICNSLTGQCVCQ 973 ++G C C P G CN+ C G+Y GC LPC+C GA C+S+TG C C Sbjct: 375 VTGACTCQPGWSGHHCNESCPVGYY-----GDGCQLPCTCQ-NGA---DCHSITGGCTCA 425 Query: 974 DASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033 + C +G P C+C+ G TC V G C CK+ G C Sbjct: 426 PGFMGEVCAVSCAAGTYG--PNCSSI--CSCNNGG----TCSPVDGSCTCKEGWQGLDCT 477 Query: 1034 ACVPSAS-HLDVNNLLGCS 1051 PS + L+ N C+ Sbjct: 478 LPCPSGTWGLNCNESCTCA 496 Score = 108 bits (270), Expect = 4e-23 Identities = 110/415 (26%), Positives = 147/415 (35%), Gaps = 101/415 (24%) Query: 565 DQVYAFNCKP-CQCNSHSKSCHYNISVDPFPFEH--FRGGGGV-CDD-CEHNTTGRNCEL 619 D + NC C C SH+ C DP G G+ CD C G NC + Sbjct: 525 DGTFGLNCSEHCDC-SHADGC------DPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 577 Query: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQN 678 C C+ G+ C G C C G C + C Sbjct: 578 S--------------------CSCENGGS------CSPEDGSCECAPGFRGPLCQRICPP 611 Query: 679 GFYNLQELDPDGCS-PCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDH-CNFGFKFL 736 GFY GC+ PC V CH SG C+C G C+ C G+ Sbjct: 612 GFYG------HGCAQPCPL----CVHSSRPCHHISGICECLPGFSGALCNQVCAGGY--- 658 Query: 737 RSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCD-TCRENFYGLDVTNCKAC 795 F + C C +G+ C+P G C+C G C C F+G + AC Sbjct: 659 --FGQDCAQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFH--AC 710 Query: 796 DCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTI 855 C S C+A+ G C C P G C + F+ + +C + Sbjct: 711 SCHNGAS-----CSAEDGACHCTPGWTGLFCTQRCPAAFFGK----------DCGRVCQC 755 Query: 856 NGSLLCNKSTGQCPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHCQMCECDSLGTLPGTICD 914 C+ +G+C C+ G TG C Q C P + Q+CEC + T CD Sbjct: 756 QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQ-----QLCECMNNST-----CD 805 Query: 915 PISGQCLCVPNRQGRRCNQC-------QPGFYISPGNATGCLPCSCHTTGAVNHI 962 ++G C C P +G RC+Q P ISP L H+ GAV I Sbjct: 806 HVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISP-----ALGAERHSVGAVTGI 855 Score = 43.9 bits (102), Expect = 0.001 Identities = 42/151 (27%), Positives = 53/151 (35%), Gaps = 47/151 (31%) Query: 929 RRCNQCQPGFYIS-------------------------------PGNATGC------LPC 951 RR +QC PG+Y S P ++GC C Sbjct: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142 Query: 952 SCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQPCNCHLSGAL 1010 S +CN +TG CVC A G RC++ C G G PC C GA Sbjct: 143 SNRCQCQNGALCNPITGACVCA-AGFRGWRCEELCAPGTHG----KGCQLPCQCR-HGA- 195 Query: 1011 NETCHLVTGQCFCKQFVTGSKCDACVPSASH 1041 +C G+C C TG C+ P SH Sbjct: 196 --SCDPRAGECLCAPGYTGVYCEELCPPGSH 224 >gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] Length = 1140 Score = 146 bits (369), Expect = 1e-34 Identities = 175/670 (26%), Positives = 234/670 (34%), Gaps = 199/670 (29%) Query: 515 SGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNC-K 573 S CQCH + CD + +C CS G +RC ++ P Y C + Sbjct: 278 SQECQCH-NGGTCDAATG--QCHCSP-----GYTGERC---QDECPVG----TYGVLCAE 322 Query: 574 PCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCE--LCKDYFFRQVGAD 631 CQC + K H + G C CE G CE LC + + Sbjct: 323 TCQCVNGGKCYHVS---------------GACL-CEAGFAGERCEARLCPEGLY------ 360 Query: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFY--------- 681 I K C C T + C + G+C CK SG CN+ C GFY Sbjct: 361 --GIKCDKRCPCHLENTHS----CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICS 414 Query: 682 --NLQELDP--------------DGCSPC-------NCNTSGTVDGDITCHQNSGQCKCK 718 N + D D +PC NC++ D C G C CK Sbjct: 415 CQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCK 474 Query: 719 ANVIG----LRCDHCNFGFKFLRSFNDVGCE-PCQCNLHGSVNKFCNPHSGQCECKKEAK 773 A G +RC +GF GC CQC L+G CN G C C + Sbjct: 475 AGWHGVDCSIRCPSGTWGF---------GCNLTCQC-LNGGA---CNTLDGTCTCAPGWR 521 Query: 774 GLQCDT-CRENFYGLDVTNC-KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK-CL 830 G +C+ C++ YGL NC + CDC A C+ TG C C P G C+ C Sbjct: 522 GEKCELPCQDGTYGL---NCAERCDCSHADG-----CHPTTGHCRCLPGWSGVHCDSVCA 573 Query: 831 EGNF--------YLRQNNSF--------------------LCLP------CNCDKTGTIN 856 EG + Y + S +C P C+ ++ Sbjct: 574 EGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVH 633 Query: 857 GSLLCNKSTGQCPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHC----------QMCEC--- 902 S C+ TG C C G TG CN+ C R+ C + C+C Sbjct: 634 SSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPG 693 Query: 903 ----DSLGTLP----------------GTICDPISGQCLCVPNRQGRRCNQ-CQPGFYIS 941 D P G C G+C C P G C Q C GFY Sbjct: 694 WIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFY-- 751 Query: 942 PGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQ 1000 L C C +HI +GQC C+ G+ C+Q C +G+ G Q Sbjct: 752 --GKDCALICQCQNGADCDHI----SGQCTCR-TGFMGRHCEQKCPSGTYGY----GCRQ 800 Query: 1001 PCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPP 1060 C+C N TC +TG C+C G++CD A + V NL S+T P Sbjct: 801 ICDC----LNNSTCDHITGTCYCSPGWKGARCD----QAGVIIVGNLNSLSRTSTALPAD 852 Query: 1061 RGQVQSSSAI 1070 Q+ + + I Sbjct: 853 SYQIGAIAGI 862 Score = 138 bits (348), Expect = 4e-32 Identities = 131/507 (25%), Positives = 187/507 (36%), Gaps = 145/507 (28%) Query: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCDD-CEHNTTGRNCELCKDYFFRQVGADPSAI 635 CN + +CH FRG C+D CE T G +C Sbjct: 160 CNPITGACHCAAG--------FRGWR--CEDRCEQGTYGNDCH----------------- 192 Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCSPC 694 + C C T CD + G+C C +G C C G + P C Sbjct: 193 ---QRCQCQNGAT------CDHVTGECRCPPGYTGAFCEDLCPPGKHG-----PQCEQRC 238 Query: 695 NCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDH-CNFGFKFLRSFNDVGCEPCQCNLHG 753 C G CH +G+C C + +G C C G F + CQC+ G Sbjct: 239 PCQNGG------VCHHVTGECSCPSGWMGTVCGQPCPEG-----RFGKNCSQECQCHNGG 287 Query: 754 SVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKT 812 + C+ +GQC C G +C D C YG V + C C G C + Sbjct: 288 T----CDAATGQCHCSPGYTGERCQDECPVGTYG--VLCAETCQCVNGGK-----CYHVS 336 Query: 813 GQCICKPNVEGRQCNK--CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPC 870 G C+C+ G +C C EG + ++ + PC+ + T + C+ +G+C C Sbjct: 337 GACLCEAGFAGERCEARLCPEGLYGIKCDKR---CPCHLENTHS------CHPMSGECAC 387 Query: 871 KLGVTGLRCNQ-CEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGR 929 K G +GL CN+ C P Y Q+C C + G CD ++G+C C P +G Sbjct: 388 KPGWSGLYCNETCSPGFYGEACQ-----QICSCQN-----GADCDSVTGKCTCAPGFKGI 437 Query: 930 RCN-QCQPGFY-ISPGNATGC--------------------------------------L 949 C+ C G Y I+ + GC L Sbjct: 438 DCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNL 497 Query: 950 PCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD-QCKDHYFGFDPQTGRCQPCNC-HLS 1007 C C GA CN+L G C C G++C+ C+D +G + + C+C H Sbjct: 498 TCQCLNGGA----CNTLDGTCTCA-PGWRGEKCELPCQDGTYGLN----CAERCDCSHAD 548 Query: 1008 GALNETCHLVTGQCFCKQFVTGSKCDA 1034 G CH TG C C +G CD+ Sbjct: 549 G-----CHPTTGHCRCLPGWSGVHCDS 570 Score = 132 bits (332), Expect = 3e-30 Identities = 129/445 (28%), Positives = 170/445 (38%), Gaps = 92/445 (20%) Query: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667 CE G NC D D C C +NG+ LC+ I G C+C Sbjct: 126 CEPGWGGTNCSSACD-------GDHWGPHCTSRCQC-----KNGA-LCNPITGACHCAAG 172 Query: 668 VSGRQC-NQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726 G +C ++C+ G Y D C C TC +G+C+C G C Sbjct: 173 FRGWRCEDRCEQGTYG-----NDCHQRCQCQNGA------TCDHVTGECRCPPGYTGAFC 221 Query: 727 -DHCNFGFKFLRSFNDVGCE---PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCR 781 D C G + CE PCQ +G V C+ +G+C C G C C Sbjct: 222 EDLCPPG------KHGPQCEQRCPCQ---NGGV---CHHVTGECSCPSGWMGTVCGQPCP 269 Query: 782 ENFYGLDVTNC-KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQC-NKCLEGNFYLRQN 839 E +G NC + C C G+ C+A TGQC C P G +C ++C G + Sbjct: 270 EGRFG---KNCSQECQCHNGGT-----CDAATGQCHCSPGYTGERCQDECPVGTY----- 316 Query: 840 NSFLCL-PCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQ--CEPHRYNLTIDNFQH 896 LC C C +NG C +G C C+ G G RC C Y + D Sbjct: 317 -GVLCAETCQC-----VNGG-KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCD---- 365 Query: 897 CQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ-CQPGFYISPGNATGCLPCSCHT 955 + C C T C P+SG+C C P G CN+ C PGFY G A + CSC Sbjct: 366 -KRCPCHLENT---HSCHPMSGECACKPGWSGLYCNETCSPGFY---GEACQQI-CSCQ- 416 Query: 956 TGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCH 1015 GA C+S+TG+C C C +G + C+ + C Sbjct: 417 NGA---DCDSVTGKCTCAPGFKGIDCSTPCPLGTYGIN--------CSSRCGCKNDAVCS 465 Query: 1016 LVTGQCFCKQFVTGSKCDACVPSAS 1040 V G C CK G C PS + Sbjct: 466 PVDGSCTCKAGWHGVDCSIRCPSGT 490 Score = 124 bits (312), Expect = 5e-28 Identities = 117/436 (26%), Positives = 166/436 (38%), Gaps = 81/436 (18%) Query: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANV 721 C C+ G C+ +G P S C C C+ +G C C A Sbjct: 124 CQCEPGWGGTNCSSACDG----DHWGPHCTSRCQCKNGAL------CNPITGACHCAAGF 173 Query: 722 IGLRC-DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQC-DT 779 G RC D C G ++ + + CQC +G+ C+ +G+C C G C D Sbjct: 174 RGWRCEDRCEQG-----TYGNDCHQRCQCQ-NGAT---CDHVTGECRCPPGYTGAFCEDL 224 Query: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK-CLEGNFYLRQ 838 C +G + C C G VC+ TG+C C G C + C EG F Sbjct: 225 CPPGKHGPQCE--QRCPCQNGG-----VCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNC 277 Query: 839 NNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRC-NQCEPHRYNLTIDNFQHC 897 + C C GT C+ +TGQC C G TG RC ++C Y + Sbjct: 278 SQE-----CQCHNGGT------CDAATGQCHCSPGYTGERCQDECPVGTYGVLC-----A 321 Query: 898 QMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ--CQPGFYISPGNATGC-LPCSCH 954 + C+C + G C +SG CLC G RC C G Y C C CH Sbjct: 322 ETCQC-----VNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY-----GIKCDKRCPCH 371 Query: 955 TTGAVNHICNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQPCNCHLSGALNET 1013 H C+ ++G+C C+ +G C++ C ++G Q Q C+C +GA Sbjct: 372 LEN--THSCHPMSGECACK-PGWSGLYCNETCSPGFYGEACQ----QICSCQ-NGA---D 420 Query: 1014 CHLVTGQCFCKQFVTGSKCDACVPSASH-LDVNNLLGCSKTPFQQPPPRGQVQSSSAINL 1072 C VTG+C C G C P ++ ++ ++ GC P V S Sbjct: 421 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSP-----VDGSCTCKA 475 Query: 1073 SWSPPD----SPNAHW 1084 W D P+ W Sbjct: 476 GWHGVDCSIRCPSGTW 491 Score = 51.2 bits (121), Expect = 8e-06 Identities = 47/151 (31%), Positives = 58/151 (38%), Gaps = 47/151 (31%) Query: 929 RRCNQCQPGFYIS-----PGNATGCL--------PCSC--------------------HT 955 RR +QC PGFY S P A C+ C C H Sbjct: 89 RRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHC 148 Query: 956 TGAV----NHICNSLTGQCVCQDASIAGQRC-DQCKDHYFGFDPQTGRCQPCNCHLSGAL 1010 T +CN +TG C C A G RC D+C+ +G D Q C C +GA Sbjct: 149 TSRCQCKNGALCNPITGACHCA-AGFRGWRCEDRCEQGTYGNDCH----QRCQCQ-NGA- 201 Query: 1011 NETCHLVTGQCFCKQFVTGSKCDACVPSASH 1041 TC VTG+C C TG+ C+ P H Sbjct: 202 --TCDHVTGECRCPPGYTGAFCEDLCPPGKH 230 >gi|122937343 platelet endothelial aggregation receptor 1 [Homo sapiens] Length = 1037 Score = 146 bits (368), Expect = 2e-34 Identities = 168/630 (26%), Positives = 214/630 (33%), Gaps = 199/630 (31%) Query: 517 RCQCHGHADNCDTTSQPYRCLCSQESF-----------TEGLHCDRCLPLYNDKPFR--Q 563 RCQCHG CD Q C C E T G C N F+ Q Sbjct: 190 RCQCHGAP--CDP--QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ 245 Query: 564 GD------QVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDD------CEHN 611 G + PC H +C GG+CD C Sbjct: 246 GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCH---------NGGLCDRFTGQCRCAPG 296 Query: 612 TTGRNC-ELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSG 670 TG C E C F Q D + CDC C G C C+ +G Sbjct: 297 YTGDRCREECPVGRFGQ--------DCAETCDCAP------DARCFPANGACLCEHGFTG 342 Query: 671 RQCNQ--CQNGFYNLQELDPDGC-SPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727 +C C +GFY L C +PC C+ + ++CH +G+C C GL Sbjct: 343 DRCTDRLCPDGFYGLS------CQAPCTCDR----EHSLSCHPMNGECSCLPGWAGL--- 389 Query: 728 HCNFGFKFLRSFNDVGC-EPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT-CRENFY 785 HCN + + GC E C C LHG V C SG C+C G C + C + Y Sbjct: 390 HCNESCP--QDTHGPGCQEHCLC-LHGGV---CQATSGLCQCAPGYTGPHCASLCPPDTY 443 Query: 786 GLDVTNCKA-CDCDTAGSL-----------------------PGT--------------- 806 G+ NC A C C+ A + PGT Sbjct: 444 GV---NCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEA 500 Query: 807 VCNAKTGQCICKPNVEGRQCN-KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKST 865 VC+ +TG C C P G C C +G F C+CD + C+ Sbjct: 501 VCSPQTGACTCTPGWHGAHCQLPCPKGQF-----GEGCASRCDCDHSDG------CDPVH 549 Query: 866 GQCPCKLGVTGLRCN-QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924 G+C C+ G G RC+ C + + N C C + GT C P +G C+C P Sbjct: 550 GRCQCQAGWMGARCHLSCPEGLWGVNCSN-----TCTCKNGGT-----CLPENGNCVCAP 599 Query: 925 NRQGRRCNQ-CQPGFYISPGNATGCLPCSCHTTGAVNH-ICNSLTGQCVCQDASIAGQRC 982 +G C + CQPG Y C+PC C NH C+ G C C A G C Sbjct: 600 GFRGPSCQRSCQPGRY-----GKRCVPCKC-----ANHSFCHPSNGTCYCL-AGWTGPDC 648 Query: 983 DQ--------------CKDHYFGF-DPQTGRC-------------------------QPC 1002 Q C+ H+ G PQ G C QPC Sbjct: 649 SQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPC 708 Query: 1003 NCHLSGALNETCHLVTGQCFCKQFVTGSKC 1032 C E CH TG C C +G+ C Sbjct: 709 QC----GPGEKCHPETGACVCPPGHSGAPC 734 Score = 128 bits (321), Expect = 5e-29 Identities = 146/584 (25%), Positives = 204/584 (34%), Gaps = 142/584 (24%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHC-DRCLPLYNDKPFRQGDQVYAFNCKP-- 574 C C G+ +CD P +CS S + +C C P Y + Q + C P Sbjct: 148 CSC-GNNSSCD----PKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQT 202 Query: 575 --CQCNSHSK------SCHYNISVDPFPFEHFRGGGGVCD------DCEHNTTGRNCEL- 619 C C + SC S P H GGV C G C L Sbjct: 203 GACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLP 262 Query: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQN 678 C + F + + C C G LCD+ GQC C +G +C + C Sbjct: 263 CPEGFHGP--------NCSQECRCHNGG------LCDRFTGQCRCAPGYTGDRCREECPV 308 Query: 679 GFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDH--CNFGFKFL 736 G + + C+P D C +G C C+ G RC C GF L Sbjct: 309 GRFGQDCAETCDCAP-----------DARCFPANGACLCEHGFTGDRCTDRLCPDGFYGL 357 Query: 737 RSFNDVGCE-PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKA 794 C+ PC C+ S++ C+P +G+C C GL C ++C ++ +G C+ Sbjct: 358 ------SCQAPCTCDREHSLS--CHPMNGECSCLPGWAGLHCNESCPQDTHG---PGCQE 406 Query: 795 -CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTG 853 C C L G VC A +G C C P G C + Y NC Sbjct: 407 HCLC-----LHGGVCQATSGLCQCAPGYTGPHCASLCPPDTY----------GVNCSARC 451 Query: 854 TINGSLLCNKSTGQCPCKLGVTGLRCN-QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912 + ++ C+ G+C CK G C+ C P + + + C+C + Sbjct: 452 SCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN-----ASCQCAH-----EAV 501 Query: 913 CDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVC 972 C P +G C C P G C P G A+ C C H+ G C+ + G+C C Sbjct: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC-DCD-HSDG-----CDPVHGRCQC 554 Query: 973 QDASIAGQRCD-QCKDHYFGFD--------------PQTG-------------------- 997 Q A G RC C + +G + P+ G Sbjct: 555 Q-AGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPG 613 Query: 998 ----RCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVP 1037 RC PC C A + CH G C+C TG C P Sbjct: 614 RYGKRCVPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQPCP 653 Score = 118 bits (296), Expect = 4e-26 Identities = 122/466 (26%), Positives = 155/466 (33%), Gaps = 120/466 (25%) Query: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCSPCNCN 697 KPC C N S CD G C+C + C Q C G+Y P C C+ Sbjct: 146 KPCSCGN----NSS--CDPKSGVCSCPSGLQPPNCLQPCTPGYYG-----PACQFRCQCH 194 Query: 698 TSGTVDGDITCHQNSGQCKCKANVIGLRCD----------------HCNFGFKFLRSFND 741 + C +G C C A G CD C G F Sbjct: 195 GA-------PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS 247 Query: 742 VGCEP-----------------------CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCD 778 C P C+C+ G C+ +GQC C A G D Sbjct: 248 CSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG----LCDRFTGQCRC---APGYTGD 300 Query: 779 TCRENF----YGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK--CLEG 832 CRE +G D + CDC P C G C+C+ G +C C +G Sbjct: 301 RCREECPVGRFGQDC--AETCDC-----APDARCFPANGACLCEHGFTGDRCTDRLCPDG 353 Query: 833 NFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTID 892 + L PC CD+ SL C+ G+C C G GL CN+ P Sbjct: 354 FYGLSCQ-----APCTCDR----EHSLSCHPMNGECSCLPGWAGLHCNESCPQD------ 398 Query: 893 NFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRC-NQCQPGFYISPGNATGCLPC 951 H C+ L L G +C SG C C P G C + C P Y C Sbjct: 399 --THGPGCQEHCL-CLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTY----GVNCSARC 451 Query: 952 SCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALN 1011 SC A C+ + G+CVC++ G C +GF CN A Sbjct: 452 SCENAIA----CSPIDGECVCKEGWQRGNCSVPCPPGTWGFS--------CNASCQCAHE 499 Query: 1012 ETCHLVTGQCFCKQFVTGSKCDACVPS-------ASHLDVNNLLGC 1050 C TG C C G+ C P AS D ++ GC Sbjct: 500 AVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGC 545 Score = 114 bits (284), Expect = 1e-24 Identities = 124/491 (25%), Positives = 170/491 (34%), Gaps = 133/491 (27%) Query: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCK-PCQCN-SHSKSCH-YNISVDP 592 CLC + FT DR P D Y +C+ PC C+ HS SCH N Sbjct: 334 CLC-EHGFTGDRCTDRLCP----------DGFYGLSCQAPCTCDREHSLSCHPMNGECSC 382 Query: 593 FPFEHFRGGGGV-CDD-CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKP---------- 640 P G G+ C++ C +T G C+ V S + C P Sbjct: 383 LP-----GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL 437 Query: 641 CDCDTVGTR-------NGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYNLQELDPDGCS 692 C DT G +I C I G+C CK C+ C P G Sbjct: 438 CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPC-----------PPGTW 486 Query: 693 PCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD-HCNFGFKFLRSFNDVGCEPCQCNL 751 +CN S + C +G C C G C C G F + C C+ Sbjct: 487 GFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKG-----QFGEGCASRCDCDH 541 Query: 752 HGSVNKFCNPHSGQCECKKEAKGLQCD-TCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810 C+P G+C+C+ G +C +C E +G++ +N C C G+ C Sbjct: 542 SDG----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSN--TCTCKNGGT-----CLP 590 Query: 811 KTGQCICKPNVEGRQCNK-CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP 869 + G C+C P G C + C G + R C+PC C C+ S G C Sbjct: 591 ENGNCVCAPGFRGPSCQRSCQPGRYGKR------CVPCKCANHS------FCHPSNGTCY 638 Query: 870 CKLGVTGLRCNQ-CEPHRYNLTIDNFQHC-QMCECDSLGTL------------------- 908 C G TG C+Q C P + ++C Q C+C GT Sbjct: 639 CLAGWTGPDCSQPCPPGHWG------ENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCL 692 Query: 909 -------------------PGTICDPISGQCLCVPNRQGRRCN-QCQPGFYISPGNATGC 948 PG C P +G C+C P G C Q F + P Sbjct: 693 EGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMP-----T 747 Query: 949 LPCSCHTTGAV 959 P + ++ GAV Sbjct: 748 TPVAYNSLGAV 758 Score = 73.6 bits (179), Expect = 1e-12 Identities = 68/263 (25%), Positives = 93/263 (35%), Gaps = 80/263 (30%) Query: 814 QCICKPNVEGRQCN-KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKL 872 QC C P G C+ +C G + + + PC+C + C+ +G C C Sbjct: 119 QCQCVPGWRGDDCSSECAPGMWGPQCDK-----PCSCGNNSS------CDPKSGVCSCPS 167 Query: 873 GVTGLRCNQ-CEPHRYNLTIDNFQHCQM-CECDSLGTLPGTICDPISGQCLCVPNRQGRR 930 G+ C Q C P Y CQ C+C G CDP +G C C R G Sbjct: 168 GLQPPNCLQPCTPGYYG------PACQFRCQCH------GAPCDPQTGACFCPAERTGPS 215 Query: 931 C----------------NQCQ-PGFYISPGNATGCLP----------------------- 950 C + CQ G + +P + C P Sbjct: 216 CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQE 275 Query: 951 CSCHTTGAVNHICNSLTGQCVCQDASIAGQRC-DQCKDHYFGFDPQTGRCQPCNCHLSGA 1009 C CH G +C+ TGQC C G RC ++C FG D + C+C A Sbjct: 276 CRCHNGG----LCDRFTGQCRCA-PGYTGDRCREECPVGRFGQD----CAETCDC----A 322 Query: 1010 LNETCHLVTGQCFCKQFVTGSKC 1032 + C G C C+ TG +C Sbjct: 323 PDARCFPANGACLCEHGFTGDRC 345 >gi|24308065 netrin 5 [Homo sapiens] Length = 489 Score = 144 bits (362), Expect = 9e-34 Identities = 81/226 (35%), Positives = 108/226 (47%), Gaps = 29/226 (12%) Query: 459 PGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRC 518 PG P F++TP + V A+ +R F GQ A LR GRC Sbjct: 112 PGALGGPERVTFHSTPGPKATVAASHLRVEFGGQ--AGLAAAGLR------------GRC 157 Query: 519 QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCN 578 QCHGHA C ++P RC C T G C+ C P + D P+R + C PC CN Sbjct: 158 QCHGHAARCAARARPPRCHCRHH--TTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215 Query: 579 SHSKSCHYNISVDPFPFEHFR--GG--GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634 H++ C +N E FR GG GGVC+ C H+T GR+C C+ F+R + Sbjct: 216 QHARRCRFNS-------ELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFS 268 Query: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGF 680 C+ C C +G G+ C+Q GQC CK V+G CN+C G+ Sbjct: 269 RRACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGPGY 312 Score = 89.7 bits (221), Expect = 2e-17 Identities = 61/182 (33%), Positives = 79/182 (43%), Gaps = 39/182 (21%) Query: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCK----DYFFRQVGA 630 CQC+ H+ C P H C H+TTG CE C+ D+ +R A Sbjct: 157 CQCHGHAARCAARARP---PRCH----------CRHHTTGPGCESCRPSHRDWPWRP--A 201 Query: 631 DPSAIDVCKPCDCDTVGTR---NGSILC---DQIGGQCN-CKRHVSGRQCNQCQNGFYNL 683 P C PC C+ R N + + GG C C+ H +GR C+ CQ GF+ Sbjct: 202 TPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR- 260 Query: 684 QELDPD-------GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFL 736 DP C C C+ G G TC+Q SGQC CK V GL C+ C G++ Sbjct: 261 ---DPSQPIFSRRACRACQCHPIGATGG--TCNQTSGQCTCKLGVTGLTCNRCGPGYQQS 315 Query: 737 RS 738 RS Sbjct: 316 RS 317 Score = 70.5 bits (171), Expect = 1e-11 Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 37/203 (18%) Query: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN--------CKACDCD 798 CQC+ H + +C C+ G C++CR + C C C+ Sbjct: 157 CQCHGHAA-RCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215 Query: 799 T--------------AGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF-- 842 +G G VC C+ + GR C+ C G + F Sbjct: 216 QHARRCRFNSELFRLSGGRSGGVCER------CRHHTAGRHCHYCQPGFWRDPSQPIFSR 269 Query: 843 -LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC- 900 C C C G G+ CN+++GQC CKLGVTGL CN+C P Y + CQ Sbjct: 270 RACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGP-GYQQSRSPRMPCQRIP 326 Query: 901 -ECDSLGTLPGTICDPISGQCLC 922 +L T PG Q C Sbjct: 327 EATTTLATTPGAYSSDPQCQNYC 349 Score = 68.6 bits (166), Expect = 5e-11 Identities = 42/140 (30%), Positives = 57/140 (40%), Gaps = 25/140 (17%) Query: 661 QCNCKRHVSGRQCNQCQNGFYN-----LQELDPDGCSPCNCNTSGTVDGDITCHQNS--- 712 +C+C+ H +G C C+ + P C PC+CN C NS Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHAR-----RCRFNSELF 228 Query: 713 --------GQC-KCKANVIGLRCDHCNFGFKFLRS---FNDVGCEPCQCNLHGSVNKFCN 760 G C +C+ + G C +C GF S F+ C CQC+ G+ CN Sbjct: 229 RLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCN 288 Query: 761 PHSGQCECKKEAKGLQCDTC 780 SGQC CK GL C+ C Sbjct: 289 QTSGQCTCKLGVTGLTCNRC 308 Score = 65.1 bits (157), Expect = 5e-10 Identities = 43/158 (27%), Positives = 63/158 (39%), Gaps = 30/158 (18%) Query: 704 GDITCHQNSG---------QCKCKANVIGLRCDHC-----NFGFKFLRSFNDVGCEPCQC 749 G CH ++ +C C+ + G C+ C ++ ++ + C PC C Sbjct: 155 GRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214 Query: 750 NLHGSVNKFCNP--------HSGQCE-CKKEAKGLQCDTCRENFYG------LDVTNCKA 794 N H +F + G CE C+ G C C+ F+ C+A Sbjct: 215 NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRA 274 Query: 795 CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEG 832 C C G+ GT CN +GQC CK V G CN+C G Sbjct: 275 CQCHPIGATGGT-CNQTSGQCTCKLGVTGLTCNRCGPG 311 Score = 64.7 bits (156), Expect = 7e-10 Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 16/167 (9%) Query: 797 CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFY-----LRQNNSFLCLPCNCDK 851 C G A+ +C C+ + G C C + + CLPC+C++ Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216 Query: 852 TGT---INGSLLC---NKSTGQCP-CKLGVTGLRCNQCEPHRY---NLTIDNFQHCQMCE 901 N L +S G C C+ G C+ C+P + + I + + C+ C+ Sbjct: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276 Query: 902 CDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948 C +G GT C+ SGQC C G CN+C PG+ S C Sbjct: 277 CHPIGATGGT-CNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322 Score = 63.2 bits (152), Expect = 2e-09 Identities = 40/137 (29%), Positives = 55/137 (40%), Gaps = 18/137 (13%) Query: 919 QCLCVPNRQGRRCNQCQPGFY------ISPGNATGCLPCSCHTTGAVNHICNSLT----- 967 +C C + G C C+P +P + CLPCSC+ + L Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233 Query: 968 ---GQCVCQDASIAGQRCDQCKDHYFGFDPQT----GRCQPCNCHLSGALNETCHLVTGQ 1020 G C AG+ C C+ ++ Q C+ C CH GA TC+ +GQ Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293 Query: 1021 CFCKQFVTGSKCDACVP 1037 C CK VTG C+ C P Sbjct: 294 CTCKLGVTGLTCNRCGP 310 >gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] Length = 1541 Score = 141 bits (356), Expect = 4e-33 Identities = 126/451 (27%), Positives = 170/451 (37%), Gaps = 108/451 (23%) Query: 602 GGVCDD-CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660 G +C++ C +T G+NC C C GT CD + G Sbjct: 548 GLICNETCPPDTFGKNCSFS--------------------CSCQNGGT------CDSVTG 581 Query: 661 QCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGC-SPCNCNTSGTVDGDITCHQNSGQCKCK 718 C C VSG C C G+Y C CNC G CH+ G C C Sbjct: 582 ACRCPPGVSGTNCEDGCPKGYYGKH------CRKKCNCANRGR------CHRLYGACLCD 629 Query: 719 ANVIG----LRCDHCNFGFKFLRSFNDVGC-EPCQCNLHGSVNKFCNPHSGQCECKKEAK 773 + G L C FG GC E CQC + + C+ G C CK + Sbjct: 630 PGLYGRFCHLTCPPWAFG---------PGCSEECQCVQPHTQS--CDKRDGSCSCKAGFR 678 Query: 774 GLQCDT-CRENFYGLDVTNC-KACDCDTAGSLPGTVCNAKTGQC--ICKPNVEGRQCNK- 828 G +C C ++G C +AC C G C++ +G+C C +G C + Sbjct: 679 GERCQAECELGYFG---PGCWQACTCPV-----GVACDSVSGECGKRCPAGFQGEDCGQE 730 Query: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN-QCEPHRY 887 C G F + ++S C+C G C+ TGQC C G TG C C R+ Sbjct: 731 CPVGTFGVNCSSS-----CSC-------GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRW 778 Query: 888 NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATG 947 L C C+ CDP +G CLC+P G RC P + P T Sbjct: 779 GLGCQEI--CPACQ-------HAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQT- 828 Query: 948 CLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQPCNCHL 1006 CSC G C+ TG C C G C + C ++G D PCNC Sbjct: 829 --RCSCANDGH----CHPATGHCSCA-PGWTGFSCQRACDTGHWGPDCS----HPCNC-- 875 Query: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVP 1037 A + +C ++G C C+ G +C+ P Sbjct: 876 -SAGHGSCDAISGLCLCEAGYVGPRCEQQCP 905 Score = 136 bits (343), Expect = 1e-31 Identities = 149/567 (26%), Positives = 191/567 (33%), Gaps = 141/567 (24%) Query: 517 RCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-C 575 RCQC H CD S C+ + G C+ P F D A NC Sbjct: 916 RCQCQ-HGAACDHVSGA----CTCPAGWRGTFCEHACPA----GFFGLDCRSACNCTAGA 966 Query: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635 C++ + SC R G + C +T G NC Sbjct: 967 ACDAVNGSCLCPAG---------RRGPRCAETCPAHTYGHNCS----------------- 1000 Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCS-P 693 + C C NG+ CD + GQC+C G C Q C G Y D C Sbjct: 1001 ---QACACF-----NGAS-CDPVHGQCHCAPGWMGPSCLQACPAGLYG------DNCRHS 1045 Query: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753 C C GT C SG C C GL C+ + L GC L+G Sbjct: 1046 CLCQNGGT------CDPVSGHCACPEGWAGLACEK-----ECLPRDVRAGCRHSGGCLNG 1094 Query: 754 SVNKFCNPHSGQCECKKEAKGLQCDT-CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKT 812 + C+PH+G+C C G +C + C ++G + C C PG C+ T Sbjct: 1095 GL---CDPHTGRCLCPAGWTGDKCQSPCLRGWFG--EACAQRCSCP-----PGAACHHVT 1144 Query: 813 GQCICKPNVEGRQCNK-CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCK 871 G C C P G C + C G+F C C C+ +TG C C Sbjct: 1145 GACRCPPGFTGSGCEQACPPGSF-----GEDCAQMCQCPGENPA-----CHPATGTCSCA 1194 Query: 872 LGVTGLRCNQ-CEPHRYNLTIDNFQHCQ----------MCECDS---------------- 904 G G C Q C P RY + C C C + Sbjct: 1195 AGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF 1254 Query: 905 -------LGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC-LPCSCHTT 956 G G CDP++G CLC P R G RC + P GC CSC Sbjct: 1255 GPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP----QNRFGVGCEHTCSCRNG 1310 Query: 957 GAVNHICNSLTGQCVCQDASIAGQRCD-QCKDHYFGFDPQTGRCQ-PCNCHLSGALNETC 1014 G +C++ G C C G+ C+ C +G C C+CH N TC Sbjct: 1311 G----LCHASNGSCSC-GLGWTGRHCELACPPGRYG-----AACHLECSCH----NNSTC 1356 Query: 1015 HLVTGQCFCKQFVTGSKCDACVPSASH 1041 TG C C G C+ P H Sbjct: 1357 EPATGTCRCGPGFYGQACEHPCPPGFH 1383 Score = 133 bits (335), Expect = 1e-30 Identities = 126/451 (27%), Positives = 170/451 (37%), Gaps = 102/451 (22%) Query: 602 GGVCDD------CEHNTTGRNCEL-CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654 GG+CD C TG C+ C +F + A + C C Sbjct: 1094 GGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACA--------QRCSCPP------GAA 1139 Query: 655 CDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSG 713 C + G C C +G C Q C G + D C C CH +G Sbjct: 1140 CHHVTGACRCPPGFTGSGCEQACPPGSFG-----EDCAQMCQCPGENPA-----CHPATG 1189 Query: 714 QCKCKANVIG----LRCDHCNFGFKFLRSFNDVGCEP-CQCNLHGSVNKFCNPHSGQCEC 768 C C A G RC +G GCE C C GS C+ +G C C Sbjct: 1190 TCSCAAGYHGPSCQQRCPPGRYG---------PGCEQLCGCLNGGS----CDAATGACRC 1236 Query: 769 KKEAKGLQCD-TCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCN 827 G C+ TC + +G + T+ C C G C+ TG C+C P G +C Sbjct: 1237 PTGFLGTDCNLTCPQGRFGPNCTH--VCGCGQ-----GAACDPVTGTCLCPPGRAGVRCE 1289 Query: 828 K-CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN-QCEPH 885 + C + F + C+ T + LC+ S G C C LG TG C C P Sbjct: 1290 RGCPQNRFGV-----------GCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPG 1338 Query: 886 RYNLTIDNFQHCQM-CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ-CQPGFYISPG 943 RY C + C C + T C+P +G C C P G+ C C PGF+ Sbjct: 1339 RYGAA------CHLECSCHNNST-----CEPATGTCRCGPGFYGQACEHPCPPGFH---- 1383 Query: 944 NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ-CKDHYFGFDPQTGRCQPC 1002 GC GA C+ ++G+C+C A G C++ C+ FG G Q C Sbjct: 1384 -GAGCQGLCWCQHGAP---CDPISGRCLCP-AGFHGHFCERGCEPGSFG----EGCHQRC 1434 Query: 1003 NCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033 +C GA C VTG C C +G+ C+ Sbjct: 1435 DCD-GGA---PCDPVTGLCLCPPGRSGATCN 1461 Score = 127 bits (318), Expect = 1e-28 Identities = 136/535 (25%), Positives = 188/535 (35%), Gaps = 118/535 (22%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHC-DRCLPLYNDKPFRQGDQVYAFNCKPCQ 576 C C + CD+ + RC G +C D C Y K R K C Sbjct: 568 CSCQ-NGGTCDSVTGACRC----PPGVSGTNCEDGCPKGYYGKHCR----------KKCN 612 Query: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL-CKDYFFRQVGADPSAI 635 C + + CH G C C+ GR C L C + F Sbjct: 613 CANRGR-CHRLY--------------GACL-CDPGLYGRFCHLTCPPWAFGP-------- 648 Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYNLQELDPDGC-SP 693 + C C T++ CD+ G C+CK G +C +C+ G++ GC Sbjct: 649 GCSEECQCVQPHTQS----CDKRDGSCSCKAGFRGERCQAECELGYFG------PGCWQA 698 Query: 694 CNCNTSGTVDGDITCHQNSGQC--KCKANVIGLRC-DHCNFGFKFLRSFNDVGCEPCQCN 750 C C + C SG+C +C A G C C G + + C C Sbjct: 699 CTCPVG------VACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPC- 751 Query: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDT-CRENFYGLDVTN-CKACDCDTAGSLPGTVC 808 HG +GQC C G C+ C E +GL C AC C Sbjct: 752 -HGV--------TGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQ-------HAARC 795 Query: 809 NAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC 868 + +TG C+C P G +C +Y + C+C G C+ +TG C Sbjct: 796 DPETGACLCLPGFVGSRCQDVCPAGWYGPSCQT----RCSCANDGH------CHPATGHC 845 Query: 869 PCKLGVTGLRCNQ-CEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQ 927 C G TG C + C+ + + C C + CD ISG CLC Sbjct: 846 SCAPGWTGFSCQRACDTGHWGPDCSH-----PCNCSA----GHGSCDAISGLCLCEAGYV 896 Query: 928 GRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQ-CK 986 G RC Q P + PG C C A +H+ +G C C A G C+ C Sbjct: 897 GPRCEQQCPQGHFGPGCEQ---RCQCQHGAACDHV----SGACTC-PAGWRGTFCEHACP 948 Query: 987 DHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASH 1041 +FG D ++ CNC A C V G C C G +C P+ ++ Sbjct: 949 AGFFGLDCRSA----CNCTAGAA----CDAVNGSCLCPAGRRGPRCAETCPAHTY 995 Score = 106 bits (264), Expect = 2e-22 Identities = 123/487 (25%), Positives = 162/487 (33%), Gaps = 118/487 (24%) Query: 515 SGRCQCHGH--ADNCDTTSQPYRCL-------CSQE-SFTEGLHCD------RCLPLYND 558 +GRC C D C + CL C+Q S G C RC P + Sbjct: 1101 TGRCLCPAGWTGDKCQSP-----CLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTG 1155 Query: 559 KPFRQGDQVYAFN---CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGR 615 Q +F + CQC + +CH G C C G Sbjct: 1156 SGCEQACPPGSFGEDCAQMCQCPGENPACH--------------PATGTCS-CAAGYHGP 1200 Query: 616 NCEL-CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN 674 +C+ C + P +C G NG CD G C C G CN Sbjct: 1201 SCQQRCPPGRY-----GPGCEQLC--------GCLNGGS-CDAATGACRCPTGFLGTDCN 1246 Query: 675 -QCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGF 733 C G + P+ C C C +G C C G+RC+ Sbjct: 1247 LTCPQGRFG-----PNCTHVCGCGQGAA------CDPVTGTCLCPPGRAGVRCERGCPQN 1295 Query: 734 KFLRSFNDVGCE-PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCD-TCRENFYGLDVTN 791 +F VGCE C C G C+ +G C C G C+ C YG Sbjct: 1296 RF-----GVGCEHTCSCRNGG----LCHASNGSCSCGLGWTGRHCELACPPGRYG---AA 1343 Query: 792 CKA-CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCD 850 C C C + C TG C C P G+ C F+ C Sbjct: 1344 CHLECSCHN-----NSTCEPATGTCRCGPGFYGQACEHPCPPGFH----------GAGCQ 1388 Query: 851 KTGTINGSLLCNKSTGQCPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHC-QMCECDSLGTL 908 C+ +G+C C G G C + CEP + + C Q C+CD Sbjct: 1389 GLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFG------EGCHQRCDCDG---- 1438 Query: 909 PGTICDPISGQCLCVPNRQGRRCN-QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLT 967 G CDP++G CLC P R G CN C+ G + P C+ H C+ ++ Sbjct: 1439 -GAPCDPVTGLCLCPPGRSGATCNLDCRRGQF-GPS-------CTLHCDCGGGADCDPVS 1489 Query: 968 GQCVCQD 974 GQC C D Sbjct: 1490 GQCHCVD 1496 Score = 97.1 bits (240), Expect = 1e-19 Identities = 100/382 (26%), Positives = 140/382 (36%), Gaps = 100/382 (26%) Query: 602 GGVCDD------CEHNTTGRNCEL-CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654 GG CD C G +C L C F P+ VC G G+ Sbjct: 1224 GGSCDAATGACRCPTGFLGTDCNLTCPQGRF-----GPNCTHVC--------GCGQGAA- 1269 Query: 655 CDQIGGQCNCKRHVSGRQCNQ-CQNGFYNLQELDPDGCS-PCNCNTSGTVDGDITCHQNS 712 CD + G C C +G +C + C + + GC C+C G CH ++ Sbjct: 1270 CDPVTGTCLCPPGRAGVRCERGCPQNRFGV------GCEHTCSCRNGGL------CHASN 1317 Query: 713 GQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEP--------CQCNLHGSVNKFCNPHSG 764 G C C G C+ + C P +C+ H N C P +G Sbjct: 1318 GSCSCGLGWTGRHCE--------------LACPPGRYGAACHLECSCHN--NSTCEPATG 1361 Query: 765 QCECKKEAKGLQCD-TCRENFYGLDVTNCKA-CDCDTAGSLPGTVCNAKTGQCICKPNVE 822 C C G C+ C F+G C+ C C G C+ +G+C+C Sbjct: 1362 TCRCGPGFYGQACEHPCPPGFHG---AGCQGLCWCQH-----GAPCDPISGRCLCPAGFH 1413 Query: 823 GRQCNK-CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN- 880 G C + C G+F + C+CD G C+ TG C C G +G CN Sbjct: 1414 GHFCERGCEPGSFGEGCHQR-----CDCD------GGAPCDPVTGLCLCPPGRSGATCNL 1462 Query: 881 QCEPHRYNLTIDNFQHCQM-CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQP--- 936 C ++ + C + C+C G CDP+SGQC CV G C + P Sbjct: 1463 DCRRGQFGPS------CTLHCDCGG-----GADCDPVSGQCHCVDGYMGPTCREGGPLRL 1511 Query: 937 --GFYISPGNATGCLPCSCHTT 956 ++ G+A G LP S T Sbjct: 1512 PENPSLAQGSA-GTLPASSRPT 1532 Score = 80.1 bits (196), Expect = 2e-14 Identities = 117/464 (25%), Positives = 159/464 (34%), Gaps = 86/464 (18%) Query: 615 RNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVS----- 669 R C+ + Q+ AD A + C +G C G C H Sbjct: 263 RGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG---CLNTQGSFKCVCHAGYELGA 319 Query: 670 -GRQCNQCQNGFYNLQELDPDGCSP----------CNCNTSGTVDGDI-TCHQ-----NS 712 GRQC + + N E + GCS C C +D D TC +S Sbjct: 320 DGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS 379 Query: 713 GQCK--CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQ--CNLHGSVNKFCNPHSGQCEC 768 C+ C N G C C G++ S + GCE + G C +G +C Sbjct: 380 PCCQQVCTNNPGGYECG-CYAGYRL--SADGCGCEDVDECASSRGGCEHHCTNLAGSFQC 436 Query: 769 KKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT-------VCNAKTGQCICKPNV 821 EA G + R L+ D G LP V + Q +V Sbjct: 437 SCEA-GYRLHEDRRGCSPLEEPMV-----DLDGELPFVRPLPHIAVLQDELPQLFQDDDV 490 Query: 822 EGRQCNKCLEGNFYLRQNNSFLCLP------CNCDKTGTINGSLLCNKSTGQCPCKLGVT 875 + L G L + F+CL C+ NG C C C G T Sbjct: 491 GADEEEAELRGEHTLTEK--FVCLDDSFGHDCSLTCDDCRNGGT-CLLGLDGCDCPEGWT 547 Query: 876 GLRCNQ-CEPHRYNLTIDNFQHCQM-CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ 933 GL CN+ C P + ++C C C + GT CD ++G C C P G C Sbjct: 548 GLICNETCPPDTFG------KNCSFSCSCQNGGT-----CDSVTGACRCPPGVSGTNCED 596 Query: 934 -CQPGFYISPGNATGC-LPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD-QCKDHYF 990 C G+Y C C+C G C+ L G C+C D + G+ C C F Sbjct: 597 GCPKGYY-----GKHCRKKCNCANRGR----CHRLYGACLC-DPGLYGRFCHLTCPPWAF 646 Query: 991 GFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDA 1034 G G + C C ++C G C CK G +C A Sbjct: 647 G----PGCSEECQC--VQPHTQSCDKRDGSCSCKAGFRGERCQA 684 Score = 38.5 bits (88), Expect = 0.051 Identities = 77/342 (22%), Positives = 116/342 (33%), Gaps = 54/342 (15%) Query: 675 QCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFK 734 +C G+ +Q+ D +GC C+ S G ++ C C G R C + Sbjct: 109 RCCRGW--MQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPR---CQYDVD 163 Query: 735 FLRSFNDVGCEPCQCNLHGSVNKFCNP----HSGQCECKK-EAKGLQCDTCRENFYGLDV 789 R+ N GC+ N GS C P H+ C + L C+ + L + Sbjct: 164 ECRTHNG-GCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTI 222 Query: 790 TNCKACDC--------DTAGSLPGTVCNAKTGQCICKPN-VEGRQCNKCLEGNFYLRQNN 840 T + C C D + + C + G C+ + V G +C G Y + Sbjct: 223 TRHR-CQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVG--YQLAAD 279 Query: 841 SFLCLPCNCDKTGTINGSLLCNKSTGQCPC------KLGVTGLRCNQCEPHRYNLTIDNF 894 C + G + C + G C +LG G +C + E N N Sbjct: 280 GKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANN 339 Query: 895 QHCQ----------MCECD---SLGTLPGT------ICDPISGQCLCVPNRQGRRCNQCQ 935 C +C C L T T D Q +C N G C C Sbjct: 340 GGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECG-CY 398 Query: 936 PGFYISPGNATGC--LPCSCHTTGAVNHICNSLTG--QCVCQ 973 G+ +S + GC + + G H C +L G QC C+ Sbjct: 399 AGYRLS-ADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCE 439 >gi|164414431 netrin G1 isoform 1 [Homo sapiens] Length = 539 Score = 127 bits (320), Expect = 6e-29 Identities = 105/382 (27%), Positives = 163/382 (42%), Gaps = 70/382 (18%) Query: 385 IIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM--KNNGDLEKPDSVNCLQL 441 I+I F S +P ++ +++ + W+ +QY+A +C AF M K+ DL + L++ Sbjct: 148 IVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQH---TVLEI 204 Query: 442 SNFTPYSRGNVTFSILT-----------PGPNYRPG---YNNFYNTPSLQEFVKATQIRF 487 YS G T S + GP R Y T L++F T +R Sbjct: 205 ICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRI 264 Query: 488 HFH----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESF 543 G+ + E ++L +YA+ +I + GRC+C+ HA C + C C E Sbjct: 265 RLLRPAVGEIFVDE--LHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--EHN 320 Query: 544 TEGLHCDRCLPLYNDKPFRQGDQV-----YAFNCKP-------CQCNSHSKSCHYNISVD 591 T G C +C Y +P+ G + A C P C+C HS C Y ++ Sbjct: 321 TTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLN 380 Query: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGT--- 648 +C C+HNT G++CELC+ +FR A +VC C C+ +G+ Sbjct: 381 TV----------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD 430 Query: 649 -RNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSP--CNCNTSGTVDGD 705 NGS G C CK +G +C++C G P+ C +C G Sbjct: 431 RCNGS-------GFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGG----- 478 Query: 706 ITCHQNSGQCKCKANVIGLRCD 727 TCH N+ +C C A G+ C+ Sbjct: 479 -TCH-NNVRCLCPAAYTGILCE 498 Score = 73.9 bits (180), Expect = 1e-12 Identities = 60/215 (27%), Positives = 90/215 (41%), Gaps = 40/215 (18%) Query: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG--------LDVTNCKACDC- 797 C+CNLH +V + N CEC+ G C C++N+ G L + A C Sbjct: 297 CKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355 Query: 798 DTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFY---LRQNNSF 842 + S+ C + +C CK N G+ C C G F + ++ Sbjct: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415 Query: 843 LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQH--CQ-- 898 +C+ C C+ G+I+ CN S G C CK G TG +C++C P N H CQ Sbjct: 416 VCIECYCNPLGSIHDR--CNGS-GFCECKTGTTGPKCDECLP-------GNSWHYGCQPN 465 Query: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ 933 +C+ + L G C + +CLC G C + Sbjct: 466 VCDNELLHCQNGGTCHN-NVRCLCPAAYTGILCEK 499 Score = 62.8 bits (151), Expect = 3e-09 Identities = 54/182 (29%), Positives = 77/182 (42%), Gaps = 34/182 (18%) Query: 886 RYNLTIDNFQHCQMCECDSLGTLPGTIC--DPISGQCLCVPNRQGRRCNQCQ-------- 935 RY I + + C+C+ L T+C D C C N G C +C+ Sbjct: 283 RYFYAISDIKVRGRCKCN----LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW 338 Query: 936 -PGFY--ISPGNATGCLPC-----SCHTTGAVNHICNSL----TGQCVCQDASIAGQRCD 983 PG Y I G A C+P +C G N C+ + T CV + GQ C+ Sbjct: 339 SPGSYLPIPKGTANTCIPSISSIGNCECFGHSNR-CSYIDLLNTVICVSCKHNTRGQHCE 397 Query: 984 QCKDHYFG-----FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038 C+ YF D + C C C+ G++++ C+ +G C CK TG KCD C+P Sbjct: 398 LCRLGYFRNASAQLDDENV-CIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455 Query: 1039 AS 1040 S Sbjct: 456 NS 457 >gi|190014607 netrin G2 [Homo sapiens] Length = 530 Score = 126 bits (317), Expect = 1e-28 Identities = 110/454 (24%), Positives = 193/454 (42%), Gaps = 74/454 (16%) Query: 316 QRYCIPNDAGDTADNRVSRLNPE-AHPLSFVNDND---VGTSWVSNVFTNI-TQLNQGVT 370 +R+C ++ N NP+ AHP + D + + T W S ++ + L +T Sbjct: 66 ERFC-SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANIT 124 Query: 371 IS----VDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM- 424 +S V+L + +++ F +PT + +++ +N W+ +Q++A +C AFGM Sbjct: 125 LSWNKTVELTDD------VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMS 178 Query: 425 -KNNGDLEKPDSVNCLQLSNFTPYSRG----NVTFSI-----LTPGPNYRPG---YNNFY 471 + D+ + L ++ ++ +V F + + GP+ R Y Sbjct: 179 ARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLE 238 Query: 472 NTPSLQEFVKATQIRFHF-----HGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN 526 + L+EF T +R G Y E NL +YA+ I + GRC+C+ HA+ Sbjct: 239 SAKGLKEFFTLTDLRMRLLRPALGGTYVQRE---NLYKYFYAISNIEVIGRCKCNLHANL 295 Query: 527 CDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-----------C 575 C +C C E T G C +C + + +R G + + P C Sbjct: 296 CSMREGSLQCEC--EHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNC 353 Query: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635 +C HS C Y ++ C C+HNT G++C+ C+ ++R A+ Sbjct: 354 ECYGHSNRCSYIDFLNVV----------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403 Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCN 695 +VC C+C+ +G+ + C++ G C C+ +G +C+ C Y Q P+ C Sbjct: 404 NVCIECNCNQIGSVHDR--CNET-GFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQ 460 Query: 696 --CNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727 C G TC QN +C C G+RC+ Sbjct: 461 LLCQNGG------TCLQNQ-RCACPRGYTGVRCE 487 Score = 87.4 bits (215), Expect = 1e-16 Identities = 66/221 (29%), Positives = 94/221 (42%), Gaps = 45/221 (20%) Query: 747 CQCNLHGSVNKFCNPHSG--QCECKKEAKGLQCDTCRENFYG--------LDVTNCKACD 796 C+CNLH ++ C+ G QCEC+ G C C++NF L + + Sbjct: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343 Query: 797 CDTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFYLRQNNSFL- 843 C TAGS C + +C CK N G+ C C G Y R ++ L Sbjct: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG--YYRNGSAELD 401 Query: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHC-- 897 C+ CNC++ G+++ CN+ TG C C+ G G +C+ C P Y Q C Sbjct: 402 DENVCIECNCNQIGSVHDR--CNE-TGFCECREGAAGPKCDDCLPTHYWR-----QGCYP 453 Query: 898 QMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ--CQP 936 +C+ D L G C + +C C G RC Q C P Sbjct: 454 NVCDDDQLLCQNGGTCLQ-NQRCACPRGYTGVRCEQPRCDP 493 Score = 82.0 bits (201), Expect = 4e-15 Identities = 63/219 (28%), Positives = 88/219 (40%), Gaps = 32/219 (14%) Query: 633 SAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELD--- 687 S I+V C C+ LC G QC C+ + +G C +C+ F Sbjct: 279 SNIEVIGRCKCNLHAN-----LCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSY 333 Query: 688 ---PDGCSPCNCNTSGTVDGDITCHQNSGQCK------------CKANVIGLRCDHCNFG 732 P G SP C T+G+ G+ C+ +S +C CK N G C HC G Sbjct: 334 LPLPHG-SPNACATAGSF-GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG 391 Query: 733 FKFLRSF---NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV 789 + S ++ C C CN GSV+ CN +G CEC++ A G +CD C Y Sbjct: 392 YYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYWRQG 450 Query: 790 TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828 CD D G C + +C C G +C + Sbjct: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488 Score = 63.5 bits (153), Expect = 1e-09 Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 29/178 (16%) Query: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISG--QCLCVPNRQGRRCNQCQPGFYISP 942 ++Y I N + C+C+ L +C G QC C N G C +C+ F Sbjct: 272 YKYFYAISNIEVIGRCKCN----LHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRS 327 Query: 943 GNATGCLPC------SCHTTGAVNHI--------CNSL----TGQCVCQDASIAGQRCDQ 984 A LP +C T G+ + C+ + CV + GQ C Sbjct: 328 WRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQH 387 Query: 985 CKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038 C+ Y+ C CNC+ G++++ C+ TG C C++ G KCD C+P+ Sbjct: 388 CRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPT 444 Score = 62.0 bits (149), Expect = 4e-09 Identities = 65/253 (25%), Positives = 99/253 (39%), Gaps = 55/253 (21%) Query: 781 RENFYGL--DVTNCKA---CDCDTAGSLPGTVCNAKTG--QCICKPNVEGRQCNKCLEGN 833 REN Y ++N + C C+ L +C+ + G QC C+ N G C KC + N Sbjct: 268 RENLYKYFYAISNIEVIGRCKCN----LHANLCSMREGSLQCECEHNTTGPDCGKCKK-N 322 Query: 834 FYLR--QNNSFLCLPCN----CDKTGTINGSLLCNKSTGQCP------------CKLGVT 875 F R + S+L LP C G+ G+ C + +C CK Sbjct: 323 FRTRSWRAGSYLPLPHGSPNACATAGSF-GNCECYGHSNRCSYIDFLNVVTCVSCKHNTR 381 Query: 876 GLRCNQCEPHRY---NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN 932 G C C Y + +D+ C C C+ +G++ + +G C C G +C+ Sbjct: 382 GQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE--TGFCECREGAAGPKCD 439 Query: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS--IAGQRCDQCKDHYF 990 C P Y GC P ++C+ Q +CQ+ + QRC C Y Sbjct: 440 DCLPTHYW----RQGCYP----------NVCDD--DQLLCQNGGTCLQNQRC-ACPRGYT 482 Query: 991 GFDPQTGRCQPCN 1003 G + RC P + Sbjct: 483 GVRCEQPRCDPAD 495 >gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo sapiens] Length = 870 Score = 126 bits (316), Expect = 2e-28 Identities = 113/418 (27%), Positives = 158/418 (37%), Gaps = 91/418 (21%) Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYNLQELDPDGCSPC 694 D C C+ T + + +C + G+C C+ G C+ +C F+ PD C Sbjct: 73 DECGIAVCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWG-----PDCKELC 126 Query: 695 NCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGS 754 +C+ G C +GQC C A G RC+H CQC HG+ Sbjct: 127 SCHPHGQ------CEDVTGQCTCHARRWGARCEHA-----------------CQCQ-HGT 162 Query: 755 VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQ 814 C+P SG C C+ G QC AC C C+ +TG Sbjct: 163 ----CHPRSGACRCEPGWWGAQC--------------ASACYCSATSR-----CDPQTGA 199 Query: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFLC------LPCNCDK-TGTINGSLLCNKSTGQ 867 C+C GR CN N + S C CD+ G C+ G Sbjct: 200 CLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR--CHPVDGT 257 Query: 868 CPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPN 925 C C+ G G C + C Y L + C C+ G P T+ + G+CL C P Sbjct: 258 CACEPGYRGKYCREPCPAGFYGLGCR--RRCGQCK----GQQPCTVAE---GRCLTCEPG 308 Query: 926 RQGRRCNQ-CQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD- 983 G +C+Q C GFY G + C PC H CN +TG+C +A G RC+ Sbjct: 309 WNGTKCDQPCATGFY-GEGCSHRCPPCRD------GHACNHVTGKCTRCNAGWIGDRCET 361 Query: 984 QCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASH 1041 +C + +G D C + + C +G+C C V G C+ P H Sbjct: 362 KCSNGTYGED--------CAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411 Score = 112 bits (281), Expect = 2e-24 Identities = 120/466 (25%), Positives = 161/466 (34%), Gaps = 125/466 (26%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-CQ 576 C+ + + +P C C F G +CD P Q + +CK C Sbjct: 80 CEGNSTCSENEVCVRPGECRCRHGYF--GANCDTKCPR----------QFWGPDCKELCS 127 Query: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCD---DCEHNTTGRNCELCKDYFFRQVGADPS 633 C+ H + C V H R G C+ C+H T C+ Sbjct: 128 CHPHGQ-CE---DVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACR------------ 171 Query: 634 AIDVCKP----CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689 C+P C + + + CD G C C GR CN Sbjct: 172 ----CEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCN--------------- 212 Query: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749 + C CN+S C Q SG+C+C+ G RCD CQC Sbjct: 213 --NQCACNSS-------PCEQQSGRCQCRERTFGARCDRY-----------------CQC 246 Query: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808 C+P G C C+ +G C + C FYGL C+ G P C Sbjct: 247 -----FRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL---GCRRRCGQCKGQQP---C 295 Query: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQ 867 G+C+ C+P G +C++ FY + S C PC CN TG+ Sbjct: 296 TVAEGRCLTCEPGWNGTKCDQPCATGFY-GEGCSHRCPPC--------RDGHACNHVTGK 346 Query: 868 CP-CKLGVTGLRC-NQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPN 925 C C G G RC +C Y + C C G+ CD SG+CLC P Sbjct: 347 CTRCNAGWIGDRCETKCSNGTYG------EDCAFV-CADCGS---GHCDFQSGRCLCSPG 396 Query: 926 RQGRRCN-QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQC 970 G CN C PG + A CSCH C+ +TG C Sbjct: 397 VHGPHCNVTCPPGLH----GADCAQACSCH-----EDTCDPVTGAC 433 >gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo sapiens] Length = 865 Score = 126 bits (316), Expect = 2e-28 Identities = 113/418 (27%), Positives = 158/418 (37%), Gaps = 91/418 (21%) Query: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYNLQELDPDGCSPC 694 D C C+ T + + +C + G+C C+ G C+ +C F+ PD C Sbjct: 73 DECGIAVCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWG-----PDCKELC 126 Query: 695 NCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGS 754 +C+ G C +GQC C A G RC+H CQC HG+ Sbjct: 127 SCHPHGQ------CEDVTGQCTCHARRWGARCEHA-----------------CQCQ-HGT 162 Query: 755 VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQ 814 C+P SG C C+ G QC AC C C+ +TG Sbjct: 163 ----CHPRSGACRCEPGWWGAQC--------------ASACYCSATSR-----CDPQTGA 199 Query: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFLC------LPCNCDK-TGTINGSLLCNKSTGQ 867 C+C GR CN N + S C CD+ G C+ G Sbjct: 200 CLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR--CHPVDGT 257 Query: 868 CPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPN 925 C C+ G G C + C Y L + C C+ G P T+ + G+CL C P Sbjct: 258 CACEPGYRGKYCREPCPAGFYGLGCR--RRCGQCK----GQQPCTVAE---GRCLTCEPG 308 Query: 926 RQGRRCNQ-CQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD- 983 G +C+Q C GFY G + C PC H CN +TG+C +A G RC+ Sbjct: 309 WNGTKCDQPCATGFY-GEGCSHRCPPCRD------GHACNHVTGKCTRCNAGWIGDRCET 361 Query: 984 QCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASH 1041 +C + +G D C + + C +G+C C V G C+ P H Sbjct: 362 KCSNGTYGED--------CAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411 Score = 112 bits (281), Expect = 2e-24 Identities = 120/466 (25%), Positives = 161/466 (34%), Gaps = 125/466 (26%) Query: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-CQ 576 C+ + + +P C C F G +CD P Q + +CK C Sbjct: 80 CEGNSTCSENEVCVRPGECRCRHGYF--GANCDTKCPR----------QFWGPDCKELCS 127 Query: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCD---DCEHNTTGRNCELCKDYFFRQVGADPS 633 C+ H + C V H R G C+ C+H T C+ Sbjct: 128 CHPHGQ-CE---DVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACR------------ 171 Query: 634 AIDVCKP----CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689 C+P C + + + CD G C C GR CN Sbjct: 172 ----CEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCN--------------- 212 Query: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749 + C CN+S C Q SG+C+C+ G RCD CQC Sbjct: 213 --NQCACNSS-------PCEQQSGRCQCRERTFGARCDRY-----------------CQC 246 Query: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808 C+P G C C+ +G C + C FYGL C+ G P C Sbjct: 247 -----FRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL---GCRRRCGQCKGQQP---C 295 Query: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQ 867 G+C+ C+P G +C++ FY + S C PC CN TG+ Sbjct: 296 TVAEGRCLTCEPGWNGTKCDQPCATGFY-GEGCSHRCPPC--------RDGHACNHVTGK 346 Query: 868 CP-CKLGVTGLRC-NQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPN 925 C C G G RC +C Y + C C G+ CD SG+CLC P Sbjct: 347 CTRCNAGWIGDRCETKCSNGTYG------EDCAFV-CADCGS---GHCDFQSGRCLCSPG 396 Query: 926 RQGRRCN-QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQC 970 G CN C PG + A CSCH C+ +TG C Sbjct: 397 VHGPHCNVTCPPGLH----GADCAQACSCH-----EDTCDPVTGAC 433 >gi|33598931 scavenger receptor class F, member 1 isoform 3 precursor [Homo sapiens] Length = 569 Score = 116 bits (291), Expect = 1e-25 Identities = 109/421 (25%), Positives = 143/421 (33%), Gaps = 142/421 (33%) Query: 660 GQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKA 719 G C CK G C+ G Y PD C C+ G C +G C+C+A Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQY----WGPDCRESCPCHPHGQ------CEPATGACQCQA 122 Query: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779 + G RC+ PC C HG C+P +G C C+ G T Sbjct: 123 DRWGARCEF-----------------PCACGPHGR----CDPATGVCHCEP---GWWSST 158 Query: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839 CR + C C+TA + C TG C+CKP GR+C+ Sbjct: 159 CR-----------RPCQCNTAAAR----CEQATGACVCKPGWWGRRCS------------ 191 Query: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899 CNC +GS C + +G+C C+ G G C Q Sbjct: 192 -----FRCNC------HGS-PCEQDSGRCACRPGWWGPECQ-----------------QQ 222 Query: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAV 959 CEC + G C SG+C C P +G RC P A C C Sbjct: 223 CEC-----VRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK------H 270 Query: 960 NHICNSLTGQC----------VCQDASIAG-------QRCDQCKDHYFGFDPQTGRCQPC 1002 N C+ TG C CQ + G Q+C C+ H +P TG CQ C Sbjct: 271 NEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCR-HGEACEPDTGHCQRC 329 Query: 1003 NCHLSG----------------------ALNETCHLVTGQCFCKQFVTGSKCDACVPSAS 1040 + G + +C VTG C C G C+A P+ Sbjct: 330 DPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGF 389 Query: 1041 H 1041 H Sbjct: 390 H 390 Score = 94.4 bits (233), Expect = 8e-19 Identities = 111/451 (24%), Positives = 151/451 (33%), Gaps = 121/451 (26%) Query: 532 QPYRCLCSQESFTEGLHCD-RCLPLYNDKPFRQGDQVYAFN-CKP----CQCNSHSKSCH 585 +P C C F G HC RC Y R+ + C+P CQC + Sbjct: 71 KPGLCRCKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGAR 128 Query: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645 P GVC CE C +PC C+T Sbjct: 129 CEFPCACGPHGRCDPATGVCH-CEPGWWSSTCR--------------------RPCQCNT 167 Query: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705 R C+Q G C CK GR+C+ CNC+ S Sbjct: 168 AAAR-----CEQATGACVCKPGWWGRRCS-----------------FRCNCHGS------ 199 Query: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765 C Q+SG+C C+ G C + C+C V C+ SG+ Sbjct: 200 -PCEQDSGRCACRPGWWGPECQ-----------------QQCEC-----VRGRCSAASGE 236 Query: 766 CECKKEAKGLQCD-TCRENFYGLDVT-NCKACDCDTAGSLPGTVCNAKTGQC-ICKPNVE 822 C C +G +C+ C +G+ +C C + C+ TG C C+P Sbjct: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEP-------CSPDTGSCESCEPGWN 289 Query: 823 GRQCNK-CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCN 880 G QC + CL G F ++ C C + C TG C C G G RC Sbjct: 290 GTQCQQPCLPGTF--GESCEQQCPHCRHGEA--------CEPDTGHCQRCDPGWLGPRCE 339 Query: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCN-QCQPGFY 939 P D C C S CD ++G C+C G CN C GF+ Sbjct: 340 DPCP-TGTFGEDCGSTCPTCVQGS--------CDTVTGDCVCSAGYWGPSCNASCPAGFH 390 Query: 940 ISPGNATGCLPCSCHTTGAVNHICNSLTGQC 970 GN +PC C +C+ ++G C Sbjct: 391 ---GNNCS-VPCEC-----PEGLCHPVSGSC 412 Score = 77.4 bits (189), Expect = 1e-13 Identities = 70/275 (25%), Positives = 93/275 (33%), Gaps = 74/275 (26%) Query: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG 866 VC K G C CKP G C+ G ++ C C G C +TG Sbjct: 68 VC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRE----SCPCHPHGQ------CEPATG 116 Query: 867 QCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNR 926 C C+ G RC C C G CDP +G C C P Sbjct: 117 ACQCQADRWGARCE-----------------FPCACGPHGR-----CDPATGVCHCEPGW 154 Query: 927 QGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD-QC 985 C + PC C+T A C TG CVC+ G+RC +C Sbjct: 155 WSSTCRR----------------PCQCNTAAA---RCEQATGACVCK-PGWWGRRCSFRC 194 Query: 986 KDHYFGFDPQTGRC------------QPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033 H + +GRC Q C C + C +G+C C G++C+ Sbjct: 195 NCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRGRCSAASGECTCPPGFRGARCE 249 Query: 1034 ACVPSASHLDVNNLLGCSKTPFQQP--PPRGQVQS 1066 P+ SH V C + +P P G +S Sbjct: 250 LPCPAGSH-GVQCAHSCGRCKHNEPCSPDTGSCES 283 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.440 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 67,521,869 Number of Sequences: 37866 Number of extensions: 3406137 Number of successful extensions: 15490 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 116 Number of HSP's successfully gapped in prelim test: 339 Number of HSP's that attempted gapping in prelim test: 8181 Number of HSP's gapped (non-prelim): 2960 length of query: 1546 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1431 effective length of database: 13,892,928 effective search space: 19880779968 effective search space used: 19880779968 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.