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Search of human proteins with 217330601
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217330601 SP140 nuclear body protein isoform 1 [Homo
sapiens]
(867 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 1793 0.0
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 793 0.0
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens] 566 e-161
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens] 345 1e-94
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 318 2e-86
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens] 275 1e-73
gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens] 275 2e-73
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens] 131 3e-30
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 103 7e-22
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 101 3e-21
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 101 3e-21
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 99 1e-20
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 89 2e-17
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens] 74 6e-13
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 65 3e-10
gi|38016945 deformed epidermal autoregulatory factor 1 [Homo sap... 65 4e-10
gi|4557293 autoimmune regulator isoform 2 [Homo sapiens] 64 8e-10
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 63 1e-09
gi|38788260 bromodomain PHD finger transcription factor isoform ... 57 1e-07
gi|38788274 bromodomain PHD finger transcription factor isoform ... 57 1e-07
gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens] 54 5e-07
gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens] 54 5e-07
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 53 1e-06
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 52 3e-06
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens] 51 4e-06
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] 51 4e-06
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 51 5e-06
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 51 5e-06
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 51 5e-06
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 49 2e-05
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 1793 bits (4645), Expect = 0.0
Identities = 867/867 (100%), Positives = 867/867 (100%)
Query: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP
Sbjct: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
Query: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL
Sbjct: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
Query: 121 MAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLLPYGKQENSNACHEMDDIAVPQE 180
MAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLLPYGKQENSNACHEMDDIAVPQE
Sbjct: 121 MAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLLPYGKQENSNACHEMDDIAVPQE 180
Query: 181 ALSSSPRCEPGFSSESCEQLALPKAGGGDAEDAPSLLPGGGVSCKLAIQIDEGESEEMPK 240
ALSSSPRCEPGFSSESCEQLALPKAGGGDAEDAPSLLPGGGVSCKLAIQIDEGESEEMPK
Sbjct: 181 ALSSSPRCEPGFSSESCEQLALPKAGGGDAEDAPSLLPGGGVSCKLAIQIDEGESEEMPK 240
Query: 241 LLPYDTEVLESNGMIDAARTYSTAPGEKQGEEEGRNSPRKRNQDKEKYQESPEGRDKETF 300
LLPYDTEVLESNGMIDAARTYSTAPGEKQGEEEGRNSPRKRNQDKEKYQESPEGRDKETF
Sbjct: 241 LLPYDTEVLESNGMIDAARTYSTAPGEKQGEEEGRNSPRKRNQDKEKYQESPEGRDKETF 300
Query: 301 DLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEMCDGEEPQEASSSLARCGSVSCLSAET 360
DLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEMCDGEEPQEASSSLARCGSVSCLSAET
Sbjct: 301 DLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEMCDGEEPQEASSSLARCGSVSCLSAET 360
Query: 361 FDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELEN 420
FDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELEN
Sbjct: 361 FDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELEN 420
Query: 421 HPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSCVMCFSEEVPGSPEARTESDQACGT 480
HPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSCVMCFSEEVPGSPEARTESDQACGT
Sbjct: 421 HPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSCVMCFSEEVPGSPEARTESDQACGT 480
Query: 481 MDTVDIANNSTLGKPKRKRRKKRGHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVN 540
MDTVDIANNSTLGKPKRKRRKKRGHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVN
Sbjct: 481 MDTVDIANNSTLGKPKRKRRKKRGHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVN 540
Query: 541 LKDLSKIRGRKRGKPGTRFTQSDRAAQKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGI 600
LKDLSKIRGRKRGKPGTRFTQSDRAAQKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGI
Sbjct: 541 LKDLSKIRGRKRGKPGTRFTQSDRAAQKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGI 600
Query: 601 LHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFL 660
LHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFL
Sbjct: 601 LHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFL 660
Query: 661 PDPPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP 720
PDPPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP
Sbjct: 661 PDPPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP 720
Query: 721 VEAERTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFA 780
VEAERTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFA
Sbjct: 721 VEAERTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFA 780
Query: 781 KIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFG 840
KIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFG
Sbjct: 781 KIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFG 840
Query: 841 QMGFRLEAEFEKNFKEVFAIQETNGNN 867
QMGFRLEAEFEKNFKEVFAIQETNGNN
Sbjct: 841 QMGFRLEAEFEKNFKEVFAIQETNGNN 867
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 793 bits (2048), Expect = 0.0
Identities = 374/405 (92%), Positives = 388/405 (95%)
Query: 463 EVPGSPEARTESDQACGTMDTVDIANNSTLGKPKRKRRKKRGHGWSRMRMRRQENSQQND 522
EVP SPEAR ESDQACG MDTVDIANNSTLGKPKRKRRKK+GHGWSRM R Q+N+QQND
Sbjct: 176 EVPESPEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQND 235
Query: 523 NSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAAQKRVRSRASRKHKDET 582
NSKADGQ+VSSEKKAN+NLKDLSKIRGRKRGKPGT FTQSDRA QKRVRSRASRKHKDET
Sbjct: 236 NSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDET 295
Query: 583 VDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRL 642
VDF+APLLPVTCGGVKGILHK+KL+QG L KCIQTEDGKWFTP EFEIKGG+ARSKNWRL
Sbjct: 296 VDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRL 355
Query: 643 SVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGEL 702
SVRCGGWPLR LME G LP+PPRI YR KKRILKSQNNSSVDPCMRNLDECEVCRDGGEL
Sbjct: 356 SVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGEL 415
Query: 703 FCCDTCSRVFHEDCHIPPVEAERTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK 762
FCCDTCSRVFHEDCHIPPVE+E+TPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK
Sbjct: 416 FCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK 475
Query: 763 CEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQD 822
CEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQD
Sbjct: 476 CEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQD 535
Query: 823 MRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVFAIQETNGNN 867
MRLIFQNHRASYKYKDFGQMG RLEAEFEK+FKEVFAIQETNGN+
Sbjct: 536 MRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS 580
Score = 132 bits (333), Expect = 1e-30
Identities = 68/170 (40%), Positives = 105/170 (61%), Gaps = 11/170 (6%)
Query: 29 EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88
E Q++ E + + +F+ F+ +K+EI++AI + FPFL GLRDR I+ +M+E +++ RNL
Sbjct: 40 EDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNL 99
Query: 89 VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNV 148
VPV RV+Y VLSELEKTF S LEALFS +N+ YPDL IY+SF+N + Q ++
Sbjct: 100 VPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDR 159
Query: 149 NDLEDRPRL-----------LPYGKQENSNACHEMDDIAVPQEALSSSPR 187
+ E+RP + P ++E+ AC +MD + + + P+
Sbjct: 160 KEREERPDIKLSLKQGEVPESPEARKESDQACGKMDTVDIANNSTLGKPK 209
>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
Length = 885
Score = 567 bits (1460), Expect = e-161
Identities = 366/908 (40%), Positives = 485/908 (53%), Gaps = 137/908 (15%)
Query: 29 EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88
E Q + +++ + +F+ F+ NKVEI++AI + FPFL GLRDR I+ +M+E Q++ RNL
Sbjct: 40 EDQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNL 99
Query: 89 VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNV 148
VPV RV+Y VLSELEKTF LEALFS +N+ YPDL IY+ F+NV ++ PLQ +
Sbjct: 100 VPVQRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEE 159
Query: 149 NDLEDRPRL---LPYGKQENSNACHEMDDIAVPQEALSSSPRCEPGFSSESCEQLALPKA 205
+ E+R L L G ENS P A ++ P E G S CE +
Sbjct: 160 EEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPP--ENGLSEHPCETEQINAK 217
Query: 206 GGGDAEDAPSLLPGGGV------------SCK-LAIQIDEGES-EEMPKLLPYDTEV--- 248
D L SC+ +A+Q++ G++ EMP LP D E
Sbjct: 218 RKDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEA 277
Query: 249 -LESNGM-----------IDAARTYSTAPGEKQGEEEGRNSPRK-----RNQDKEKYQES 291
L ++G+ I + +S + E Q + ++ ++D E +
Sbjct: 278 ELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDV 337
Query: 292 PEG--------RDKETFDLKTPQVTN-EGEPEKGLCLLPGEGEEGSD------------- 329
E R + + P +N E E ++ C P E D
Sbjct: 338 DEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKK 397
Query: 330 -------DCSEMCDGEEPQEASSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLP 382
D SE + E P EASS G++ E + + + P ++
Sbjct: 398 RVIGQDHDFSESSEEEAPAEASS-----GALRSKHGEKAPMTSRSTSTWRIPSRKRRF-- 450
Query: 383 GEGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELENHPMNEEGESEELASSLLYDNVP 442
S D S++ +GEE QE SS RRGS
Sbjct: 451 -----SSSDFSDLSNGEELQETCSSSLRRGS----------------------------- 476
Query: 443 GAEQSAYENEKCSCVMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGKPKRKRRKK 502
G++ EN+KCSCVMCF + VP S EARTES QA MDT+D+ NNSTL K KRRKK
Sbjct: 477 GSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKK 536
Query: 503 RGHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQS 562
R H R ++ + ++ D + K +N K + K R ++RG+ ++
Sbjct: 537 RRH---RSKVNGLQRGRKKDRPR---------KHLTLNNK-VQKKRWQQRGR------KA 577
Query: 563 DRAAQKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKW 622
+ KR R R R KDE ++FK LPVTCG VKG L+K++ +QG KCIQ+ED KW
Sbjct: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
Query: 623 FTPTEFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSS 682
FTP EFEI+G SKNW+LS+RCGG+ L+ LMEN FLP+PP R KKRIL+S NN+
Sbjct: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTR---KKRILESHNNTL 694
Query: 683 VDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTPWNCIFCRMK----ES 738
VDPC N + CEVC G LFCCDTC R FHE CHIP VEA + PW+CIFCR+K
Sbjct: 695 VDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERC 754
Query: 739 PGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEP 798
P SQ QESEVL RQM PEEQLKCEFLLLKVYC S+S FFA PYY RE QG ++P
Sbjct: 755 PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASEPYYN--REGSQGPQKP 812
Query: 799 MWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVF 858
MWL+K+K LNE Y +VEGFVQDMRLIF NH+ Y+ F ++G +++ FEKNF+ +F
Sbjct: 813 MWLNKVKTSLNEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIF 872
Query: 859 AIQETNGN 866
AIQET+ N
Sbjct: 873 AIQETSKN 880
>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
Length = 879
Score = 345 bits (885), Expect = 1e-94
Identities = 255/724 (35%), Positives = 354/724 (48%), Gaps = 131/724 (18%)
Query: 29 EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88
E Q + +++ + +F+ F+ NKVEI++AI + FPFL GLRDR I+ +M+E Q++ RNL
Sbjct: 40 EDQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNL 99
Query: 89 VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNV 148
VPV RV+Y VLSELEKTF LEALFS +N+ YPDL IY+ F+NV ++ PLQ +
Sbjct: 100 VPVQRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEE 159
Query: 149 NDLEDRPRL---LPYGKQENSNACHEMDDIAVPQEALSSSPRCEPGFSSESCEQLALPKA 205
+ E+R L L G ENS P A ++ P E G S CE +
Sbjct: 160 EEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPP--ENGLSEHPCETEQINAK 217
Query: 206 GGGDAEDAPSLLPGGGV------------SCK-LAIQIDEGES-EEMPKLLPYDTEV--- 248
D L SC+ +A+Q++ G++ EMP LP D E
Sbjct: 218 RKDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEA 277
Query: 249 -LESNGM-----------IDAARTYSTAPGEKQGEEEGRNSPRK-----RNQDKEKYQES 291
L ++G+ I + +S + E Q + ++ ++D E +
Sbjct: 278 ELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDV 337
Query: 292 PEG--------RDKETFDLKTPQVTN-EGEPEKGLCLLPGEGEEGSD------------- 329
E R + + P +N E E ++ C P E D
Sbjct: 338 DEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKK 397
Query: 330 -------DCSEMCDGEEPQEASSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLP 382
D SE + E P EASS G++ E + + + P ++
Sbjct: 398 RVIGQDHDFSESSEEEAPAEASS-----GALRSKHGEKAPMTSRSTSTWRIPSRKRRF-- 450
Query: 383 GEGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELENHPMNEEGESEELASSLLYDNVP 442
S D S++ +GEE QE SS RRGS
Sbjct: 451 -----SSSDFSDLSNGEELQETCSSSLRRGS----------------------------- 476
Query: 443 GAEQSAYENEKCSCVMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGKPKRKRRKK 502
G++ EN+KCSCVMCF + VP S EARTES QA MDT+D+ NNSTL K KRRKK
Sbjct: 477 GSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKK 536
Query: 503 RGHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQS 562
R H R ++ + ++ D + K +N K + K R ++RG+ ++
Sbjct: 537 RRH---RSKVNGLQRGRKKDRPR---------KHLTLNNK-VQKKRWQQRGR------KA 577
Query: 563 DRAAQKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKW 622
+ KR R R R KDE ++FK LPVTCG VKG L+K++ +QG KCIQ+ED KW
Sbjct: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
Query: 623 FTPTEFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSS 682
FTP EFEI+G SKNW+LS+RCGG+ L+ LMEN FLP+PP R KKRIL+S NN+
Sbjct: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTR---KKRILESHNNTL 694
Query: 683 VDPC 686
VDPC
Sbjct: 695 VDPC 698
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 318 bits (814), Expect = 2e-86
Identities = 212/598 (35%), Positives = 298/598 (49%), Gaps = 69/598 (11%)
Query: 291 SPEGRDKETFDLKTPQVTNEG-EPEKGLCLLPGEGEEG------SDDCSEMCDGEEPQEA 343
+P + T ++ ++ +E P + LP +EG +D + + EE E
Sbjct: 153 APRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEE 212
Query: 344 SSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQE 403
SL +V S D PQ+ ++ +P++ G E D+ E D EE QE
Sbjct: 213 MPSLLT-STVQVAS----DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQE 267
Query: 404 ASSSLA-------RRGSVSSELENHPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSC 456
SS+ + +R S+ H + + + +Q + + +C
Sbjct: 268 VSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTC 327
Query: 457 VMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGK-----PKRKRRKKRG-----HG 506
+ +ARTE + + + +D + GK P RR +G HG
Sbjct: 328 NSTVETR---AQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHG 384
Query: 507 WSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAA 566
+ +Q+ D+S + +V+ +KA K K R +++ K + S R
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRF 442
Query: 567 QKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPT 626
QK + R K K +TVDF LPVTCG KGIL+KKK++ G VKCI+ EDG W TP
Sbjct: 443 QKNIHRRG--KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPN 500
Query: 627 EFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPC 686
EFE++G +KNW+ ++RC G L L++
Sbjct: 501 EFEVEGKGRNAKNWKRNIRCEGMTLGELLKR----------------------------- 531
Query: 687 MRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTPWNCIFCRMKESPGSQQCCQ 746
+N DECEVC GG+L CC TC RVFHEDCHIPPVEA+R W+C FCRMK S GSQQC
Sbjct: 532 -KNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHH 590
Query: 747 ESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKK 806
S+ LERQM P++QLKCEFLLLK YC +SSFF IP + IR+ + +E MWLD +K+
Sbjct: 591 VSKTLERQMQPQDQLKCEFLLLKAYCHPQSSFFTGIP--FNIRDYGEPFQEAMWLDLVKE 648
Query: 807 RLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVFAIQETN 864
RL Y V FV+DMRL+F+NH+ YK DFGQ+G LEAEFEK+ K+V E N
Sbjct: 649 RLITEMY-TVAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEAN 705
Score = 117 bits (293), Expect = 5e-26
Identities = 109/375 (29%), Positives = 166/375 (44%), Gaps = 76/375 (20%)
Query: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
Query: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLL- 158
++LE+TF S L LFS+INL YP+L IYRSF+ V + D P LL
Sbjct: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYE-------RQSRDTPILLE 122
Query: 159 -PYGKQENSNACHEMDDIAVPQEALSSSPRC-----EPGFSSESCEQLALPKAGGGD-AE 211
P G E S + H + PQ S C EPG SS+ +++ D
Sbjct: 123 APTGLAEGS-SLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVL 181
Query: 212 DAPSLLPGGG----VSCKLAIQID-EGESEEMPKLLPYDTEVLESN-------------- 252
P+L+ G + KL +++ E +SEEMP LL +V N
Sbjct: 182 PLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEM 241
Query: 253 -----GMIDAAR-------------TYSTAPGEKQGEEEGR---NSPRKRNQDK------ 285
G + R S+ P +K+G++ R ++P++R++ K
Sbjct: 242 PHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGT 301
Query: 286 -----------EKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEM 334
++ + P+ +D T + V + + C EE D SEM
Sbjct: 302 ASSRHGIQKKLKRVDQVPQKKDDSTCN---STVETRAQKARTECARKSRSEEIIDGTSEM 358
Query: 335 CDGEEPQEASSSLAR 349
+G+ Q+ S+ R
Sbjct: 359 NEGKRSQKTPSTPRR 373
>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
Length = 689
Score = 275 bits (704), Expect = 1e-73
Identities = 196/598 (32%), Positives = 280/598 (46%), Gaps = 93/598 (15%)
Query: 291 SPEGRDKETFDLKTPQVTNEG-EPEKGLCLLPGEGEEG------SDDCSEMCDGEEPQEA 343
+P + T ++ ++ +E P + LP +EG +D + + EE E
Sbjct: 153 APRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEE 212
Query: 344 SSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQE 403
SL +V S D PQ+ ++ +P++ G E D+ E D EE QE
Sbjct: 213 MPSLLT-STVQVAS----DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQE 267
Query: 404 ASSSLA-------RRGSVSSELENHPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSC 456
SS+ + +R S+ H + + + +Q + + +C
Sbjct: 268 VSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTC 327
Query: 457 VMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGK-----PKRKRRKKRG-----HG 506
+ +ARTE + + + +D + GK P RR +G HG
Sbjct: 328 NSTVETR---AQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHG 384
Query: 507 WSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAA 566
+ +Q+ D+S + +V+ +KA K K R +++ K + S R
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRF 442
Query: 567 QKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPT 626
QK + R K K +TVDF LPVTCG KGIL+KKK++ G VKCI+ EDG W TP
Sbjct: 443 QKNIHRRG--KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPN 500
Query: 627 EFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPC 686
EFE++G +KNW+ ++RC G L L++
Sbjct: 501 EFEVEGKGRNAKNWKRNIRCEGMTLGELLKR----------------------------- 531
Query: 687 MRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTPWNCIFCRMKESPGSQQCCQ 746
+N DECEVC GG+L CC TC RVFHEDCHIPPVEA+R W+C FCRMK S GSQQC
Sbjct: 532 -KNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHH 590
Query: 747 ESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKK 806
S+ LERQM P++QL IR+ + +E MWLD +K+
Sbjct: 591 VSKTLERQMQPQDQL--------------------------IRDYGEPFQEAMWLDLVKE 624
Query: 807 RLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVFAIQETN 864
RL Y V FV+DMRL+F+NH+ YK DFGQ+G LEAEFEK+ K+V E N
Sbjct: 625 RLITEMY-TVAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEAN 681
Score = 117 bits (293), Expect = 5e-26
Identities = 109/375 (29%), Positives = 166/375 (44%), Gaps = 76/375 (20%)
Query: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
Query: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLL- 158
++LE+TF S L LFS+INL YP+L IYRSF+ V + D P LL
Sbjct: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYE-------RQSRDTPILLE 122
Query: 159 -PYGKQENSNACHEMDDIAVPQEALSSSPRC-----EPGFSSESCEQLALPKAGGGD-AE 211
P G E S + H + PQ S C EPG SS+ +++ D
Sbjct: 123 APTGLAEGS-SLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVL 181
Query: 212 DAPSLLPGGG----VSCKLAIQID-EGESEEMPKLLPYDTEVLESN-------------- 252
P+L+ G + KL +++ E +SEEMP LL +V N
Sbjct: 182 PLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEM 241
Query: 253 -----GMIDAAR-------------TYSTAPGEKQGEEEGR---NSPRKRNQDK------ 285
G + R S+ P +K+G++ R ++P++R++ K
Sbjct: 242 PHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGT 301
Query: 286 -----------EKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEM 334
++ + P+ +D T + V + + C EE D SEM
Sbjct: 302 ASSRHGIQKKLKRVDQVPQKKDDSTCN---STVETRAQKARTECARKSRSEEIIDGTSEM 358
Query: 335 CDGEEPQEASSSLAR 349
+G+ Q+ S+ R
Sbjct: 359 NEGKRSQKTPSTPRR 373
>gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]
Length = 172
Score = 275 bits (702), Expect = 2e-73
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP
Sbjct: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
Query: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL
Sbjct: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
Query: 121 MAYPDLNEIYRSFQN 135
MAYPDLNEIYRSFQN
Sbjct: 121 MAYPDLNEIYRSFQN 135
>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
Length = 549
Score = 131 bits (329), Expect = 3e-30
Identities = 112/405 (27%), Positives = 181/405 (44%), Gaps = 36/405 (8%)
Query: 291 SPEGRDKETFDLKTPQVTNEG-EPEKGLCLLPGEGEEG------SDDCSEMCDGEEPQEA 343
+P + T ++ ++ +E P + LP +EG +D + + EE E
Sbjct: 153 APRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEE 212
Query: 344 SSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQE 403
SL +V S D PQ+ ++ +P++ G E D+ E D EE QE
Sbjct: 213 MPSLLT-STVQVAS----DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQE 267
Query: 404 ASSSLA-------RRGSVSSELENHPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSC 456
SS+ + +R S+ H + + + +Q + + +C
Sbjct: 268 VSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTC 327
Query: 457 VMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGK-----PKRKRRKKRG-----HG 506
+ +ARTE + + + +D + GK P RR +G HG
Sbjct: 328 NSTVETR---AQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHG 384
Query: 507 WSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAA 566
+ +Q+ D+S + +V+ +KA K K R +++ K + S R
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRF 442
Query: 567 QKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPT 626
QK + R K K +TVDF LPVTCG KGIL+KKK++ G VKCI+ EDG W TP
Sbjct: 443 QKNIHRRG--KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPN 500
Query: 627 EFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKK 671
EFE++G +KNW+ ++RC G L L+++G L PPRI +++
Sbjct: 501 EFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRINLKRE 545
Score = 117 bits (293), Expect = 5e-26
Identities = 109/375 (29%), Positives = 166/375 (44%), Gaps = 76/375 (20%)
Query: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
Query: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLL- 158
++LE+TF S L LFS+INL YP+L IYRSF+ V + D P LL
Sbjct: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYE-------RQSRDTPILLE 122
Query: 159 -PYGKQENSNACHEMDDIAVPQEALSSSPRC-----EPGFSSESCEQLALPKAGGGD-AE 211
P G E S + H + PQ S C EPG SS+ +++ D
Sbjct: 123 APTGLAEGS-SLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVL 181
Query: 212 DAPSLLPGGG----VSCKLAIQID-EGESEEMPKLLPYDTEVLESN-------------- 252
P+L+ G + KL +++ E +SEEMP LL +V N
Sbjct: 182 PLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEM 241
Query: 253 -----GMIDAAR-------------TYSTAPGEKQGEEEGR---NSPRKRNQDK------ 285
G + R S+ P +K+G++ R ++P++R++ K
Sbjct: 242 PHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGT 301
Query: 286 -----------EKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEM 334
++ + P+ +D T + V + + C EE D SEM
Sbjct: 302 ASSRHGIQKKLKRVDQVPQKKDDSTCN---STVETRAQKARTECARKSRSEEIIDGTSEM 358
Query: 335 CDGEEPQEASSSLAR 349
+G+ Q+ S+ R
Sbjct: 359 NEGKRSQKTPSTPRR 373
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 103 bits (257), Expect = 7e-22
Identities = 72/212 (33%), Positives = 101/212 (47%), Gaps = 24/212 (11%)
Query: 663 PPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP-V 721
P R + RI NN DP N D C VC++GG+L CC+ C +VFH CH+P +
Sbjct: 863 PIRSLMHRSARIGGDGNNKDDDP---NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLL 919
Query: 722 EAERTPWNCIFCRMKESPGSQQCCQESEVLER-----QMCPEEQLKCEFLLLKVYCCSES 776
W C FCR P + C + ++ + P +Q KCE LLL +YC S
Sbjct: 920 SFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELS 979
Query: 777 SFF-----AKIPYYYYIREACQGLKEPMWLDKIKKRL---NEHGYPQVEGFVQDMRLIFQ 828
F A IP YY I +K+PM L +KK+L + Y + FV D+RLIF+
Sbjct: 980 IEFQEPVPASIPNYYKI------IKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFK 1033
Query: 829 N-HRASYKYKDFGQMGFRLEAEFEKNFKEVFA 859
N R + + Q G + FE E+++
Sbjct: 1034 NCERFNEADSEVAQAGKAVALYFEDKLTEIYS 1065
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 101 bits (251), Expect = 3e-21
Identities = 71/188 (37%), Positives = 92/188 (48%), Gaps = 25/188 (13%)
Query: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCRMKESPGSQQCC-- 745
N D C VC++GGEL CC+ C +VFH CH+P + W C FCR P + C
Sbjct: 825 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 884
Query: 746 ----QESEVLER--QMCPEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQG 794
E + E ++ P ++ KCE LLL +YC S F +P YY I
Sbjct: 885 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKI------ 938
Query: 795 LKEPMWLDKIKKRLNE--HGYPQVEGFVQDMRLIFQNHRASYKYKD--FGQMGFRLEAEF 850
+K PM L IKKRL E Y + E FV D RLIFQN A + D G +LE F
Sbjct: 939 IKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQN-CAEFNEPDSEVANAGIKLENYF 997
Query: 851 EKNFKEVF 858
E+ K ++
Sbjct: 998 EELLKNLY 1005
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 101 bits (251), Expect = 3e-21
Identities = 71/188 (37%), Positives = 92/188 (48%), Gaps = 25/188 (13%)
Query: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCRMKESPGSQQCC-- 745
N D C VC++GGEL CC+ C +VFH CH+P + W C FCR P + C
Sbjct: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850
Query: 746 ----QESEVLER--QMCPEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQG 794
E + E ++ P ++ KCE LLL +YC S F +P YY I
Sbjct: 851 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKI------ 904
Query: 795 LKEPMWLDKIKKRLNE--HGYPQVEGFVQDMRLIFQNHRASYKYKD--FGQMGFRLEAEF 850
+K PM L IKKRL E Y + E FV D RLIFQN A + D G +LE F
Sbjct: 905 IKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQN-CAEFNEPDSEVANAGIKLENYF 963
Query: 851 EKNFKEVF 858
E+ K ++
Sbjct: 964 EELLKNLY 971
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 99.4 bits (246), Expect = 1e-20
Identities = 66/181 (36%), Positives = 89/181 (49%), Gaps = 23/181 (12%)
Query: 663 PPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP-V 721
P R + RI NN DP N D C VC++GG+L CC+ C +VFH CH+P +
Sbjct: 863 PIRSLMHRSARIGGDGNNKDDDP---NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLL 919
Query: 722 EAERTPWNCIFCRMKESPGSQQCCQESEVLER-----QMCPEEQLKCEFLLLKVYCCSES 776
W C FCR P + C + ++ + P +Q KCE LLL +YC S
Sbjct: 920 SFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELS 979
Query: 777 SFF-----AKIPYYYYIREACQGLKEPMWLDKIKKRL---NEHGYPQVEGFVQDMRLIFQ 828
F A IP YY I +K+PM L +KK+L + Y + FV D+RLIF+
Sbjct: 980 IEFQEPVPASIPNYYKI------IKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFK 1033
Query: 829 N 829
N
Sbjct: 1034 N 1034
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 88.6 bits (218), Expect = 2e-17
Identities = 60/183 (32%), Positives = 86/183 (46%), Gaps = 12/183 (6%)
Query: 687 MRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP-VEAERTPWNCIFCRMKESPGSQQCC 745
+ N D C VC +GGEL CCD C +VFH CH+P + W C CR P + C
Sbjct: 967 IENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDC 1026
Query: 746 QESEVLERQMCPE------EQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPM 799
+ + + M +Q KCE L+L + CC+ S P R Q +K PM
Sbjct: 1027 ENACYNQPGMRASPGLSMYDQKKCEKLVLSL-CCNNLSLPFHEPVSPLARHYYQIIKRPM 1085
Query: 800 WLDKIKKRLNEHG---YPQVEGFVQDMRLIFQN-HRASYKYKDFGQMGFRLEAEFEKNFK 855
L I+++L + Y E V D+RL+F N + +Y + + G LE FE K
Sbjct: 1086 DLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLK 1145
Query: 856 EVF 858
E++
Sbjct: 1146 EIY 1148
>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
Length = 545
Score = 73.9 bits (180), Expect = 6e-13
Identities = 56/148 (37%), Positives = 72/148 (48%), Gaps = 10/148 (6%)
Query: 590 LPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRLSVRCGGW 649
+P G V+GIL ++ + G KCIQ G+++TP++FE G KN S G
Sbjct: 199 VPGARGAVEGILIQQVFESGGSKKCIQV-GGEFYTPSKFEDSGS---GKNKARS-SSGPK 253
Query: 650 PL-RWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPCM--RNLDECEVCRDGGELFCCD 706
PL R G P R ++ + S DP + +N DEC VCRDGGEL CCD
Sbjct: 254 PLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPS-DPQLHQKNEDECAVCRDGGELICCD 312
Query: 707 TCSRVFHEDCHIPPV-EAERTPWNCIFC 733
C R FH C PP+ E W C C
Sbjct: 313 GCPRAFHLACLSPPLREIPSGTWRCSSC 340
Score = 33.9 bits (76), Expect = 0.67
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 693 CEVCRDGGELFCCDTCSRVFHEDCHIP 719
C VC DG ++ C C+ FH CH P
Sbjct: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFP 460
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 65.1 bits (157), Expect = 3e-10
Identities = 85/354 (24%), Positives = 133/354 (37%), Gaps = 32/354 (9%)
Query: 231 DEGESEEMPKLLPYDTEVLESNGMIDAARTYSTAPGEKQGEEEGRNSPRKRNQDKEKYQ- 289
D+GE EE + E E G ++ ++ EEEG + ++E+ +
Sbjct: 792 DQGEGEE--EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG 849
Query: 290 ESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEMCDGEEPQEASSSLAR 349
E EG K + + + EGE +G GE EEG + E +GE +E
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEG----EGEEEEGEGEGEEEGEGEGEEEEGEGEGE 905
Query: 350 CGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEM---CDGEERQEASS 406
E + K + EGE E E GEGE+G + E +GEE +
Sbjct: 906 EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965
Query: 407 SLARRGSVSSELENHPMNEEGESE---ELASSLLYDNVPGAEQSAYENEKCSCVMCFSEE 463
E E EEGE E E + G E+ E E EE
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE---------EE 1016
Query: 464 VPGSPEARTESDQACGTMDTVDIANNSTLGKPKRKRRKKRGHGWSRMRMRRQENSQQNDN 523
G E E ++ G + + G+ + + R+K G G R R +E ++
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEE-------GEEEGEEREKEGEGEENRRNREEEEEEEGKY 1069
Query: 524 SKADGQVVSSEKKANVNLKDLSKIRGR-KRGKPGTRFTQSDRAAQKRVRSRASR 576
+ + +E++ K +SKI+G K GK T +S Q + + S+
Sbjct: 1070 QETGEE--ENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSK 1121
Score = 45.8 bits (107), Expect = 2e-04
Identities = 55/225 (24%), Positives = 90/225 (40%), Gaps = 42/225 (18%)
Query: 208 GDAEDAPSLLPGGGVSCKLAIQIDEGESEEMPKLLPYDTEVLESNGMIDAARTYSTAPGE 267
G+AED P G G +G EE + + G D R PGE
Sbjct: 645 GEAEDGPE---GRG----------DGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691
Query: 268 KQGEEEGRNSPRKRNQDKEKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEG 327
+ E + +KR+ ++++ +E +G KE + ++ GE E G GE EEG
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKE----RNQEMEEGGEEEHG----EGEEEEG 743
Query: 328 SDDCSEMCDGEEPQEASSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEE 387
+ E +GE +E E +++ + EGE +KE G+ E+
Sbjct: 744 DREEEEEKEGEGKEE---------------GEGEEVEGEREKEEGERKKEER--AGKEEK 786
Query: 388 GSDDCSEMCDGEERQEASSSLARRGSVSSELENHPMNE-EGESEE 431
G ++ + GE +E + E+E + E +GE EE
Sbjct: 787 GEEEGDQ---GEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828
Score = 42.0 bits (97), Expect = 0.002
Identities = 62/305 (20%), Positives = 112/305 (36%), Gaps = 39/305 (12%)
Query: 265 PGEKQGEEEGR-NSPRKRNQDKEKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGE 323
P EK+G E+ + N ++ + + G KE ++ + +T++ E +G GE
Sbjct: 587 PEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGE 646
Query: 324 GEEGSDDCSEMCDGEEPQEASSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPG 383
E+G + G+ E SS A D ++ GE EKEL+
Sbjct: 647 AEDGPEG-----RGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA---- 697
Query: 384 EGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELENHPMNEEGESEELASSLLYDNVPG 443
E EE + DGEE+++ + + E+E E GE EE G
Sbjct: 698 EKEEW-----KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEE---------EEG 743
Query: 444 AEQSAYENEKCSCVMCFSEEVPGSPE------------ARTESDQACGTMDTVDIANNST 491
+ E E EEV G E + E + G +
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803
Query: 492 LGKPKRKRRKKRGHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRK 551
G+ K + + G + R+E ++ + + +G+ E++ ++ + +G +
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE---GEEEEGEGEEEEGEGKGEE 860
Query: 552 RGKPG 556
G+ G
Sbjct: 861 EGEEG 865
Score = 33.9 bits (76), Expect = 0.67
Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 14/118 (11%)
Query: 266 GEKQGEEEGRNSPRKRNQDKEKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGE 325
GE +GE EG + ++E+ +E E R+KE + + E E E+G GE E
Sbjct: 1019 GEVEGEVEGEEG--EGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Query: 326 EGSDDCSEMCDGEEPQEASSSLARCGSVSCLSAETFDLKTPQVTN-EGEPEKELSLLP 382
+E DGEE ++ S GSV +T+ K+ VTN +G +++ S +P
Sbjct: 1077 ------NERQDGEEYKKVSKIK---GSVKYGKHKTYQKKS--VTNTQGNGKEQRSKMP 1123
>gi|38016945 deformed epidermal autoregulatory factor 1 [Homo
sapiens]
Length = 565
Score = 64.7 bits (156), Expect = 4e-10
Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 590 LPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRLSVRCGGW 649
LPV C + G L+K +L G +CI+ + W++PTEFE G A SK+W+ S+R G
Sbjct: 203 LPVRCRNISGTLYKNRLGSGGRGRCIKQGEN-WYSPTEFEAMAGRASSKDWKRSIRYAGR 261
Query: 650 PLRWLMENGFL 660
PL+ L+++G L
Sbjct: 262 PLQCLIQDGIL 272
>gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]
Length = 348
Score = 63.5 bits (153), Expect = 8e-10
Identities = 27/49 (55%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 686 CMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFC 733
C +N DEC VCRDGGEL CCD C R FH C PP+ E W C C
Sbjct: 95 CQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 143
Score = 33.9 bits (76), Expect = 0.67
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 693 CEVCRDGGELFCCDTCSRVFHEDCHIP 719
C VC DG ++ C C+ FH CH P
Sbjct: 237 CGVCGDGTDVLRCTHCAAAFHWRCHFP 263
>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
Length = 835
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 17/178 (9%)
Query: 693 CEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCR----MKESPGSQQC-CQ 746
C VC+ G+L C+ C FH DCH+P + + W+C C +KE GS
Sbjct: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGA 687
Query: 747 ESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEP---MWLDK 803
+S + ++ P Q KCE +LL ++C P + ++ L +P + L
Sbjct: 688 DSTGVVAKLSPANQRKCERVLLALFCHEPCR-----PLHQLATDSTFSLDQPGGTLDLTL 742
Query: 804 IKKRLNEH---GYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVF 858
I+ RL E Y + F QD+ +F+ + K Q L+ FE E F
Sbjct: 743 IRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAF 800
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 56.6 bits (135), Expect = 1e-07
Identities = 24/58 (41%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 691 DECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCRMKESPGSQQCCQE 747
D C VC G+L CC+TCS V+H +C PP+ E W C C + PG C E
Sbjct: 391 DHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAE 448
Score = 32.3 bits (72), Expect = 1.9
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 29/178 (16%)
Query: 400 ERQEASSSLARRGSVSSELENHPMNEEGESE--ELASSLLYDNVPGAEQSAYENEKCSCV 457
E+ E S A +G+ +E++ + E+ + + EL S +++K
Sbjct: 1094 EKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDS--------------DSDK---- 1135
Query: 458 MCFSEEVPGSPEARTESDQACGTMDTVDIANNS------TLGKPKRKRRKKRGHGWSRMR 511
C E + + +TES C VD+ N S T K K K K G R++
Sbjct: 1136 PCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIK 1195
Query: 512 MRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAAQKR 569
E Q+ + K +G + K + + K+LS+ + K G QSD Q++
Sbjct: 1196 QFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEG---CQSDSMRQEQ 1250
Score = 32.3 bits (72), Expect = 1.9
Identities = 53/207 (25%), Positives = 88/207 (42%), Gaps = 29/207 (14%)
Query: 669 RKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFC-CDTCSRVFHEDC-HIPPVEAERT 726
+KKK I + + D + + C+ D + + CD C +H C I EAE
Sbjct: 2707 KKKKMISTTSKETKKDTKLYCI--CKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELI 2764
Query: 727 P-WNCIFCRMKE------SPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFF 779
+ C C+ E +P +++ + E L+R + + K + L+ +++
Sbjct: 2765 DEYVCPQCQSTEDAMTVLTPLTEK---DYEGLKRVLRSLQAHKMAWPFLEPVDPNDA--- 2818
Query: 780 AKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKD- 838
P YY + +KEPM L +++R+ Y ++ FV DM IF N R Y D
Sbjct: 2819 ---PDYYGV------IKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCR-YYNPSDS 2868
Query: 839 -FGQMGFRLEAEFEKNFKEVFAIQETN 864
F Q LE+ F + K A + N
Sbjct: 2869 PFYQCAEVLESFFVQKLKGFKASRSHN 2895
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 56.6 bits (135), Expect = 1e-07
Identities = 24/58 (41%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 691 DECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCRMKESPGSQQCCQE 747
D C VC G+L CC+TCS V+H +C PP+ E W C C + PG C E
Sbjct: 391 DHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAE 448
Score = 32.3 bits (72), Expect = 1.9
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 29/178 (16%)
Query: 400 ERQEASSSLARRGSVSSELENHPMNEEGESE--ELASSLLYDNVPGAEQSAYENEKCSCV 457
E+ E S A +G+ +E++ + E+ + + EL S +++K
Sbjct: 968 EKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDS--------------DSDK---- 1009
Query: 458 MCFSEEVPGSPEARTESDQACGTMDTVDIANNS------TLGKPKRKRRKKRGHGWSRMR 511
C E + + +TES C VD+ N S T K K K K G R++
Sbjct: 1010 PCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIK 1069
Query: 512 MRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAAQKR 569
E Q+ + K +G + K + + K+LS+ + K G QSD Q++
Sbjct: 1070 QFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEG---CQSDSMRQEQ 1124
Score = 32.3 bits (72), Expect = 1.9
Identities = 53/207 (25%), Positives = 88/207 (42%), Gaps = 29/207 (14%)
Query: 669 RKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFC-CDTCSRVFHEDC-HIPPVEAERT 726
+KKK I + + D + + C+ D + + CD C +H C I EAE
Sbjct: 2724 KKKKMISTTSKETKKDTKLYCI--CKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELI 2781
Query: 727 P-WNCIFCRMKE------SPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFF 779
+ C C+ E +P +++ + E L+R + + K + L+ +++
Sbjct: 2782 DEYVCPQCQSTEDAMTVLTPLTEK---DYEGLKRVLRSLQAHKMAWPFLEPVDPNDA--- 2835
Query: 780 AKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKD- 838
P YY + +KEPM L +++R+ Y ++ FV DM IF N R Y D
Sbjct: 2836 ---PDYYGV------IKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCR-YYNPSDS 2885
Query: 839 -FGQMGFRLEAEFEKNFKEVFAIQETN 864
F Q LE+ F + K A + N
Sbjct: 2886 PFYQCAEVLESFFVQKLKGFKASRSHN 2912
>gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]
Length = 1004
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Query: 671 KKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTP--- 727
+KR K + N D C+ C++GG+L CCD C FH C PP+ E P
Sbjct: 37 EKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGE 96
Query: 728 WNCIFCRMKESPGSQQ 743
W C C ++ Q+
Sbjct: 97 WMCHRCTVRRKKREQK 112
>gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]
Length = 704
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
Query: 671 KKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTP--- 727
+KR K + N D C+ C++GG+L CCD C FH C PP+ E P
Sbjct: 37 EKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGE 96
Query: 728 WNCIFCRMKESPGSQQ 743
W C C ++ Q+
Sbjct: 97 WMCHRCTVRRKKREQK 112
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 53.1 bits (126), Expect = 1e-06
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 667 RYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVE-AER 725
R RKKKRI + + D CEVC+ GGE+ CDTC R +H C P +E A
Sbjct: 325 RRRKKKRIDDGDGYET-----DHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPE 379
Query: 726 TPWNCIFCRMKESPGSQ-QCCQESEVLERQMCPEEQ 760
W+C C E G Q + + + E C EE+
Sbjct: 380 GKWSCPHC---EKEGIQWEPKDDDDEEEEGGCEEEE 412
Score = 49.7 bits (117), Expect = 1e-05
Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCRMKESPGSQQ 743
+++ C VC+DGGEL CCD C +H C PP+ E W C C G Q
Sbjct: 415 HMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQ 470
Score = 32.7 bits (73), Expect = 1.5
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 11/104 (10%)
Query: 460 FSEEVPGSPEARTESDQACGTMDTVDIANNSTLGKPKRKRRKKRGHGWSRMRMRRQENSQ 519
F+EE+ E E D D D + PK+K+ KK + + +++E S
Sbjct: 15 FAEEMENEDEMSEEEDGGLEAFD--DFFPVEPVSLPKKKKPKKLKENKCKGKRKKKEGSN 72
Query: 520 Q---------NDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGK 554
+ S+++G S KK LKD + + +++ K
Sbjct: 73 DELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKKAKRKKK 116
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 51.6 bits (122), Expect = 3e-06
Identities = 23/56 (41%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFCRMKESPGSQQ 743
+++ C VC+DGGEL CCDTC +H C PP+ E W C C G Q
Sbjct: 448 HMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQ 503
Score = 50.4 bits (119), Expect = 7e-06
Identities = 27/74 (36%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 667 RYRKKKRILKSQNNSSVDPCM------RNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP 720
R RKK R K + + + D CEVC+ GGE+ CDTC R +H C P
Sbjct: 341 RSRKKLRTTKKKKKGEEEVTAVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPD 400
Query: 721 VE-AERTPWNCIFC 733
+E A W+C C
Sbjct: 401 MEKAPEGKWSCPHC 414
>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
Length = 634
Score = 51.2 bits (121), Expect = 4e-06
Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 691 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVEA-ERTPWNCIFCR 734
D C VCR G+L CDTCSRV+H DC PP++ + W C C+
Sbjct: 443 DFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
Length = 680
Score = 51.2 bits (121), Expect = 4e-06
Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 691 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVEA-ERTPWNCIFCR 734
D C VCR G+L CDTCSRV+H DC PP++ + W C C+
Sbjct: 489 DFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 533
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 50.8 bits (120), Expect = 5e-06
Identities = 34/88 (38%), Positives = 43/88 (48%), Gaps = 12/88 (13%)
Query: 669 RKKKRILKSQ---NNSSVDPCMRN-LDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAE 724
RKKK++L VD + D CEVC+ GGE+ CDTC R +H C P E +
Sbjct: 354 RKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDP--ELD 411
Query: 725 RTP---WNCIFCRMKESPGSQQCCQESE 749
R P W+C C E G Q +E E
Sbjct: 412 RAPEGKWSCPHC---EKEGVQWEAKEEE 436
Score = 47.8 bits (112), Expect = 4e-05
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFC 733
+++ C VC+DGGEL CCD C +H C PP+ + W C C
Sbjct: 455 HMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 50.8 bits (120), Expect = 5e-06
Identities = 34/88 (38%), Positives = 43/88 (48%), Gaps = 12/88 (13%)
Query: 669 RKKKRILKSQ---NNSSVDPCMRN-LDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAE 724
RKKK++L VD + D CEVC+ GGE+ CDTC R +H C P E +
Sbjct: 354 RKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDP--ELD 411
Query: 725 RTP---WNCIFCRMKESPGSQQCCQESE 749
R P W+C C E G Q +E E
Sbjct: 412 RAPEGKWSCPHC---EKEGVQWEAKEEE 436
Score = 47.8 bits (112), Expect = 4e-05
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFC 733
+++ C VC+DGGEL CCD C +H C PP+ + W C C
Sbjct: 455 HMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 50.8 bits (120), Expect = 5e-06
Identities = 34/88 (38%), Positives = 43/88 (48%), Gaps = 12/88 (13%)
Query: 669 RKKKRILKSQ---NNSSVDPCMRN-LDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAE 724
RKKK++L VD + D CEVC+ GGE+ CDTC R +H C P E +
Sbjct: 413 RKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDP--ELD 470
Query: 725 RTP---WNCIFCRMKESPGSQQCCQESE 749
R P W+C C E G Q +E E
Sbjct: 471 RAPEGKWSCPHC---EKEGVQWEAKEEE 495
Score = 47.8 bits (112), Expect = 4e-05
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 689 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-EAERTPWNCIFC 733
+++ C VC+DGGEL CCD C +H C PP+ + W C C
Sbjct: 514 HMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 559
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 49.3 bits (116), Expect = 2e-05
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 10/163 (6%)
Query: 669 RKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTPW 728
+KKK L + NN D RN C VC G++ CC+ C RV+H C E E W
Sbjct: 64 KKKKPGLLNSNNKEQDG--RNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPE-GDW 120
Query: 729 NCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK--CEFLLLKVYCCSESSFFAKIPYYY 786
C C + C E++ M EQL +F + K+ +F +P
Sbjct: 121 FCPECEKI----TVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQ 176
Query: 787 YIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQN 829
+ + + + PM L ++K + Y E F+ D + I N
Sbjct: 177 H-PDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHN 218
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,695,567
Number of Sequences: 37866
Number of extensions: 1957301
Number of successful extensions: 7584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 301
Number of HSP's that attempted gapping in prelim test: 6495
Number of HSP's gapped (non-prelim): 1168
length of query: 867
length of database: 18,247,518
effective HSP length: 111
effective length of query: 756
effective length of database: 14,044,392
effective search space: 10617560352
effective search space used: 10617560352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.