Guide to the Human Genome
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Search of human proteins with 215982798

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215982798 sirtuin 1 isoform b [Homo sapiens]
         (452 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215982798 sirtuin 1 isoform b [Homo sapiens]                       923   0.0  
gi|7657575 sirtuin 1 isoform a [Homo sapiens]                         923   0.0  
gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]                        167   2e-41
gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]                        167   2e-41
gi|63054862 sirtuin 3 isoform b [Homo sapiens]                        155   7e-38
gi|6912660 sirtuin 3 isoform a [Homo sapiens]                         155   7e-38
gi|6912664 sirtuin 5 isoform 1 [Homo sapiens]                          70   5e-12
gi|13787215 sirtuin 5 isoform 2 [Homo sapiens]                         67   3e-11
gi|6912662 sirtuin 4 [Homo sapiens]                                    57   3e-08
gi|7706710 sirtuin 6 [Homo sapiens]                                    53   6e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           37   0.028
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           37   0.028
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    37   0.048
gi|58082089 hypothetical protein LOC161394 [Homo sapiens]              37   0.048
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...    36   0.063
gi|197313732 pleckstrin homology-like domain, family B, member 2...    36   0.082
gi|197313730 pleckstrin homology-like domain, family B, member 2...    36   0.082
gi|197313728 pleckstrin homology-like domain, family B, member 2...    36   0.082
gi|21955172 pleckstrin homology-like domain, family B, member 2 ...    36   0.082
gi|212275945 male-specific lethal 3-like 1 isoform a [Homo sapiens]    35   0.11 
gi|17975759 male-specific lethal 3-like 1 isoform b [Homo sapiens]     35   0.11 
gi|17975755 male-specific lethal 3-like 1 isoform d [Homo sapiens]     35   0.11 
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         33   0.69 
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         33   0.69 
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    33   0.69 
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    33   0.69 
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    33   0.69 
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    33   0.69 
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    33   0.69 
gi|29789072 zinc finger, ZZ-type containing 3 [Homo sapiens]           32   0.90 

>gi|215982798 sirtuin 1 isoform b [Homo sapiens]
          Length = 452

 Score =  923 bits (2386), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 1   MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60
           MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG
Sbjct: 1   MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60

Query: 61  IQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFG 120
           IQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFG
Sbjct: 61  IQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFG 120

Query: 121 ENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFD 180
           ENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFD
Sbjct: 121 ENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFD 180

Query: 181 VELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVS 240
           VELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVS
Sbjct: 181 VELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVS 240

Query: 241 EDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQM 300
           EDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQM
Sbjct: 241 EDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQM 300

Query: 301 ENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGA 360
           ENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGA
Sbjct: 301 ENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGA 360

Query: 361 EVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGA 420
           EVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGA
Sbjct: 361 EVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGA 420

Query: 421 GFGTDGDDQEAINEAISVKQEVTDMNYPSNKS 452
           GFGTDGDDQEAINEAISVKQEVTDMNYPSNKS
Sbjct: 421 GFGTDGDDQEAINEAISVKQEVTDMNYPSNKS 452


>gi|7657575 sirtuin 1 isoform a [Homo sapiens]
          Length = 747

 Score =  923 bits (2386), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 1   MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60
           MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG
Sbjct: 296 MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 355

Query: 61  IQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFG 120
           IQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFG
Sbjct: 356 IQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFG 415

Query: 121 ENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFD 180
           ENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFD
Sbjct: 416 ENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFD 475

Query: 181 VELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVS 240
           VELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVS
Sbjct: 476 VELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVS 535

Query: 241 EDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQM 300
           EDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQM
Sbjct: 536 EDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQM 595

Query: 301 ENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGA 360
           ENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGA
Sbjct: 596 ENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGA 655

Query: 361 EVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGA 420
           EVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGA
Sbjct: 656 EVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGA 715

Query: 421 GFGTDGDDQEAINEAISVKQEVTDMNYPSNKS 452
           GFGTDGDDQEAINEAISVKQEVTDMNYPSNKS
Sbjct: 716 GFGTDGDDQEAINEAISVKQEVTDMNYPSNKS 747


>gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]
          Length = 389

 Score =  167 bits (422), Expect = 2e-41
 Identities = 80/176 (45%), Positives = 125/176 (71%), Gaps = 9/176 (5%)

Query: 1   MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60
           +F+I YF+K P PFF  AKE+YPGQF+P++CH F+ L   +G LLR YTQNIDTLE++AG
Sbjct: 118 IFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAG 177

Query: 61  IQR--IIQCHGSFATASCL--ICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEI 116
           +++  +++ HG+F T+ C+   C+++     ++  IF++V P+C  C      +++KP+I
Sbjct: 178 LEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQ-----SLVKPDI 232

Query: 117 VFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINRE 172
           VFFGE+LP +F   M+ D  +VDLL+V+G+SL+V+P A + S  P   P++LIN+E
Sbjct: 233 VFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKE 288


>gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]
          Length = 352

 Score =  167 bits (422), Expect = 2e-41
 Identities = 80/176 (45%), Positives = 125/176 (71%), Gaps = 9/176 (5%)

Query: 1   MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60
           +F+I YF+K P PFF  AKE+YPGQF+P++CH F+ L   +G LLR YTQNIDTLE++AG
Sbjct: 81  IFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAG 140

Query: 61  IQR--IIQCHGSFATASCL--ICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEI 116
           +++  +++ HG+F T+ C+   C+++     ++  IF++V P+C  C      +++KP+I
Sbjct: 141 LEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQ-----SLVKPDI 195

Query: 117 VFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINRE 172
           VFFGE+LP +F   M+ D  +VDLL+V+G+SL+V+P A + S  P   P++LIN+E
Sbjct: 196 VFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKE 251


>gi|63054862 sirtuin 3 isoform b [Homo sapiens]
          Length = 257

 Score =  155 bits (392), Expect = 7e-38
 Identities = 83/206 (40%), Positives = 129/206 (62%), Gaps = 13/206 (6%)

Query: 1   MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60
           +F++ +F  +P+PFF  AKE+YPG ++P++ H F+ L   +G LLR YTQNID LE+V+G
Sbjct: 37  IFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSG 96

Query: 61  I--QRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVF 118
           I   ++++ HG+FA+A+C +C+     E +R D+    VPRCP C       ++KP+IVF
Sbjct: 97  IPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC-----TGVVKPDIVF 151

Query: 119 FGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLH 178
           FGE LP++F   +  D    DLL+++G+SL+V P A +  ++   VP++LINR+ +  L 
Sbjct: 152 FGEPLPQRFLLHV-VDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLA 210

Query: 179 F-----DVELLGDCDVIINELCHRLG 199
           +     DV  LGD    +  L   LG
Sbjct: 211 WHPRSRDVAQLGDVVHGVESLVELLG 236


>gi|6912660 sirtuin 3 isoform a [Homo sapiens]
          Length = 399

 Score =  155 bits (392), Expect = 7e-38
 Identities = 83/206 (40%), Positives = 129/206 (62%), Gaps = 13/206 (6%)

Query: 1   MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60
           +F++ +F  +P+PFF  AKE+YPG ++P++ H F+ L   +G LLR YTQNID LE+V+G
Sbjct: 179 IFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSG 238

Query: 61  I--QRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVF 118
           I   ++++ HG+FA+A+C +C+     E +R D+    VPRCP C       ++KP+IVF
Sbjct: 239 IPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC-----TGVVKPDIVF 293

Query: 119 FGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLH 178
           FGE LP++F   +  D    DLL+++G+SL+V P A +  ++   VP++LINR+ +  L 
Sbjct: 294 FGEPLPQRFLLHV-VDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLA 352

Query: 179 F-----DVELLGDCDVIINELCHRLG 199
           +     DV  LGD    +  L   LG
Sbjct: 353 WHPRSRDVAQLGDVVHGVESLVELLG 378


>gi|6912664 sirtuin 5 isoform 1 [Homo sapiens]
          Length = 310

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 58/205 (28%), Positives = 90/205 (43%), Gaps = 23/205 (11%)

Query: 14  FFKFAKEIYPGQFQPSLCHKFIALSD----KEGKLLRNYTQNIDTLEQVAGIQRIIQCHG 69
           F+ + +E+  G  +P+  H+ IA  +    K+G+ +   TQNID L + AG + +++ HG
Sbjct: 101 FYHYRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHG 159

Query: 70  SFATASCLIC-----KYKVD-CEAVRGDIFNQV--------VPRCPRCPADEPLAIMKPE 115
           S     C  C      YK   C A+ G    +         V + PRC       +++P 
Sbjct: 160 SLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPH 219

Query: 116 IVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI-PSSIPHEVPQILINREPL 174
           +V+FGENL       +  +    DL +V+G+S  V P A+  P      VP    N E  
Sbjct: 220 VVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETT 279

Query: 175 PHLH-FDVELLGDCDVIINE--LCH 196
           P  + F     G C   + E   CH
Sbjct: 280 PATNRFRFHFQGPCGTTLPEALACH 304


>gi|13787215 sirtuin 5 isoform 2 [Homo sapiens]
          Length = 299

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 55/197 (27%), Positives = 88/197 (44%), Gaps = 20/197 (10%)

Query: 14  FFKFAKEIYPGQFQPSLCHKFIALSD----KEGKLLRNYTQNIDTLEQVAGIQRIIQCHG 69
           F+ + +E+  G  +P+  H+ IA  +    K+G+ +   TQNID L + AG + +++ HG
Sbjct: 101 FYHYRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHG 159

Query: 70  SFATASCLIC-----KYKVD-CEAVRGDIFNQV--------VPRCPRCPADEPLAIMKPE 115
           S     C  C      YK   C A+ G    +         V + PRC       +++P 
Sbjct: 160 SLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPH 219

Query: 116 IVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI-PSSIPHEVPQILINREPL 174
           +V+FGENL       +  +    DL +V+G+S  V P A+  P      VP    N E  
Sbjct: 220 VVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETT 279

Query: 175 PHLHFDVELLGDCDVII 191
           P  +    L+    +II
Sbjct: 280 PATNRFSHLISISSLII 296


>gi|6912662 sirtuin 4 [Homo sapiens]
          Length = 314

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 50/152 (32%), Positives = 73/152 (48%), Gaps = 34/152 (22%)

Query: 27  QPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLIC------- 79
           QP+  H  ++  +K GKL    TQN+D L   AG +R+ + HG      CL C       
Sbjct: 120 QPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSRRLTELHGCMDRVLCLDCGEQTPRG 179

Query: 80  ----KYKV-----DCE----AVRGDIF---NQV----VPRCPRCPADEPLAIMKPEIVFF 119
               +++V       E    A  GD+F    QV    VP C +C        +KP++VFF
Sbjct: 180 VLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGH-----LKPDVVFF 234

Query: 120 GENL-PEQFHRAMKYDKDEVDLLIVIGSSLKV 150
           G+ + P++     K  K E D L+V+GSSL+V
Sbjct: 235 GDTVNPDKVDFVHKRVK-EADSLLVVGSSLQV 265


>gi|7706710 sirtuin 6 [Homo sapiens]
          Length = 355

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 55/247 (22%), Positives = 99/247 (40%), Gaps = 22/247 (8%)

Query: 27  QPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR--IIQCHGSFATASCLICKYKVD 84
           +P+  H  +   ++ G L    +QN+D L   +G  R  + + HG+     C  CK +  
Sbjct: 90  RPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYV 149

Query: 85  CEAVRGDIFNQVVPRCPRCPADEPLAIMKPE----IVFFGENLPEQFHRAMKYDKDEVDL 140
            + V G +  +   R         L   + E    I+ + ++LP++            DL
Sbjct: 150 RDTVVGTMGLKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADL 209

Query: 141 LIVIGSSLKVRPVALIPSSIPHEVPQ-ILINREPLPH-LHFDVELLGDCDVIINELCHRL 198
            I +G+SL++RP   +P +      + +++N +P  H  H D+ + G  D ++  L   L
Sbjct: 210 SITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMEHL 269

Query: 199 GGE--------YAKLCCNPV------KLSEITEKPPRTQKELAYLSELPPTPLHVSEDSS 244
           G E          +    P+      KL    E P R    +    +  P   H   + +
Sbjct: 270 GLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPA 329

Query: 245 SPERTSP 251
           SP+R  P
Sbjct: 330 SPKRERP 336


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 51/221 (23%), Positives = 95/221 (42%), Gaps = 30/221 (13%)

Query: 242 DSSSPERTSPPDSS--VIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTS-RNVESIAE 298
           +S+  +R  P   S  ++   L  +  +N  +  ++ K   E K +E Q S RN    A+
Sbjct: 53  ESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDAD 112

Query: 299 QMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFH 358
           +     ++   S++ E  +       VRK  P R AK   S   DG++ + L  +R    
Sbjct: 113 RK----IRLSSSASREPYKNQPEKTCVRKRDPERRAK---SPTPDGSERIGLEVDRRASR 165

Query: 359 GA-----EVYSDSEDDVLSSSSCGSNSDSGTC---QSPSLEEPMEDESEIEEFYNGLEDE 410
            +     EV S+       + S GS+ + G     +   +EE +E++ E+EE     E++
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE---DAEED 222

Query: 411 PDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNK 451
            +V E         DG+++E   E    ++E  +  Y  ++
Sbjct: 223 EEVDE---------DGEEEEEEEEEEEEEEEEEEEEYEQDE 254


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 51/221 (23%), Positives = 95/221 (42%), Gaps = 30/221 (13%)

Query: 242 DSSSPERTSPPDSS--VIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTS-RNVESIAE 298
           +S+  +R  P   S  ++   L  +  +N  +  ++ K   E K +E Q S RN    A+
Sbjct: 53  ESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDAD 112

Query: 299 QMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFH 358
           +     ++   S++ E  +       VRK  P R AK   S   DG++ + L  +R    
Sbjct: 113 RK----IRLSSSASREPYKNQPEKTCVRKRDPERRAK---SPTPDGSERIGLEVDRRASR 165

Query: 359 GA-----EVYSDSEDDVLSSSSCGSNSDSGTC---QSPSLEEPMEDESEIEEFYNGLEDE 410
            +     EV S+       + S GS+ + G     +   +EE +E++ E+EE     E++
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE---DAEED 222

Query: 411 PDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNK 451
            +V E         DG+++E   E    ++E  +  Y  ++
Sbjct: 223 EEVDE---------DGEEEEEEEEEEEEEEEEEEEEYEQDE 254


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 12/89 (13%)

Query: 364 SDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPD----------- 412
           +DS+ +  S S   S+S+SG+ +S S E   ED+ E EE   G E E             
Sbjct: 691 ADSDPESESESDSKSSSESGSGESSS-ESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKK 749

Query: 413 VPERAGGAGFGTDGDDQEAINEAISVKQE 441
           VPER G A    +G D  + +    +  E
Sbjct: 750 VPERKGEASSSDEGSDSSSSSSESEMTSE 778


>gi|58082089 hypothetical protein LOC161394 [Homo sapiens]
          Length = 674

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 8/90 (8%)

Query: 212 LSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDL 271
           L E   +PP+  K        P TP     +S+  +RT PP+ + +  L  +  KS+++ 
Sbjct: 225 LEETDLQPPKMTK--------PETPEETQRESTEKKRTEPPEQARLEFLEKEPRKSSEEA 276

Query: 272 DVSESKGCMEEKPQEVQTSRNVESIAEQME 301
            +   +    E P+E+Q     E   E  E
Sbjct: 277 GLEPPEETQPEVPEEMQRKATEEKGTELPE 306


>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3
           [Homo sapiens]
          Length = 1585

 Score = 36.2 bits (82), Expect = 0.063
 Identities = 57/268 (21%), Positives = 97/268 (36%), Gaps = 31/268 (11%)

Query: 180 DVELLGDCDVI--INELCHRLGG-----EYAKLCCNPVKLS-EITEKPPRTQKELAYLSE 231
           D+ L+   ++I  IN +  +L       E  K    P+ L  EI E PP   K     + 
Sbjct: 346 DIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAP 405

Query: 232 LPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDD-------LDVSES-KGCMEEK 283
           + P+ +     +      SPP + VIV        S          L+  ES + C+ E 
Sbjct: 406 ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSED 465

Query: 284 PQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGTVRKCWP-----NRVAKEQI 338
            +E+Q    VE+  +  E  D +N+ S          +A TV K W       R  +E +
Sbjct: 466 AKEIQNKIEVEADGQTEEILDSQNLNSR--RSPVPAQIAITVPKTWKKPKDRTRTTEEML 523

Query: 339 SRRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDES 398
              L+      L  ++ +        +SE D +S         S   +  ++EE  E+  
Sbjct: 524 EAELELKAEEELSIDKVL--------ESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAE 575

Query: 399 EIEEFYNGLEDEPDVPERAGGAGFGTDG 426
            +      + +   +   +G      DG
Sbjct: 576 PVRNGAESVSEGEGIDANSGSTDSSGDG 603


>gi|197313732 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 35.8 bits (81), Expect = 0.082
 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 12/121 (9%)

Query: 208 NPVKLSEITEKPP-------RTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIV-- 258
           N   LS++T  PP       +   E +YLS LP TP  +SE+  S E  +  ++ +++  
Sbjct: 540 NDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILN 599

Query: 259 ---TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEK 315
               L  +    ND +D S  +  ME    + +       + ++ E  D  N   +  EK
Sbjct: 600 NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEK 659

Query: 316 N 316
           N
Sbjct: 660 N 660


>gi|197313730 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 35.8 bits (81), Expect = 0.082
 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 12/121 (9%)

Query: 208 NPVKLSEITEKPP-------RTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIV-- 258
           N   LS++T  PP       +   E +YLS LP TP  +SE+  S E  +  ++ +++  
Sbjct: 540 NDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILN 599

Query: 259 ---TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEK 315
               L  +    ND +D S  +  ME    + +       + ++ E  D  N   +  EK
Sbjct: 600 NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEK 659

Query: 316 N 316
           N
Sbjct: 660 N 660


>gi|197313728 pleckstrin homology-like domain, family B, member 2
           isoform b [Homo sapiens]
          Length = 1237

 Score = 35.8 bits (81), Expect = 0.082
 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 12/121 (9%)

Query: 208 NPVKLSEITEKPP-------RTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIV-- 258
           N   LS++T  PP       +   E +YLS LP TP  +SE+  S E  +  ++ +++  
Sbjct: 567 NDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILN 626

Query: 259 ---TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEK 315
               L  +    ND +D S  +  ME    + +       + ++ E  D  N   +  EK
Sbjct: 627 NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEK 686

Query: 316 N 316
           N
Sbjct: 687 N 687


>gi|21955172 pleckstrin homology-like domain, family B, member 2
           isoform c [Homo sapiens]
          Length = 1210

 Score = 35.8 bits (81), Expect = 0.082
 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 12/121 (9%)

Query: 208 NPVKLSEITEKPP-------RTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIV-- 258
           N   LS++T  PP       +   E +YLS LP TP  +SE+  S E  +  ++ +++  
Sbjct: 540 NDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILN 599

Query: 259 ---TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEK 315
               L  +    ND +D S  +  ME    + +       + ++ E  D  N   +  EK
Sbjct: 600 NLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEK 659

Query: 316 N 316
           N
Sbjct: 660 N 660


>gi|212275945 male-specific lethal 3-like 1 isoform a [Homo sapiens]
          Length = 521

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)

Query: 251 PPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGS 310
           P   SV+  L  +    ND+  +S S  C E K +E+    ++E   E  E P+L+    
Sbjct: 107 PGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQ---- 162

Query: 311 STGEKNERT 319
           +  E  ERT
Sbjct: 163 TRREMEERT 171


>gi|17975759 male-specific lethal 3-like 1 isoform b [Homo sapiens]
          Length = 462

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)

Query: 251 PPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGS 310
           P   SV+  L  +    ND+  +S S  C E K +E+    ++E   E  E P+L+    
Sbjct: 48  PGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQ---- 103

Query: 311 STGEKNERT 319
           +  E  ERT
Sbjct: 104 TRREMEERT 112


>gi|17975755 male-specific lethal 3-like 1 isoform d [Homo sapiens]
          Length = 416

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)

Query: 251 PPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGS 310
           P   SV+  L  +    ND+  +S S  C E K +E+    ++E   E  E P+L+    
Sbjct: 107 PGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQ---- 162

Query: 311 STGEKNERT 319
           +  E  ERT
Sbjct: 163 TRREMEERT 171


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 38/161 (23%), Positives = 65/161 (40%), Gaps = 9/161 (5%)

Query: 163 EVPQILINREPLPHLHFDVELLGDCDVIINELC---HRLGGEYAKLCCNPVKLSEITEKP 219
           E  QIL ++ PLP    + E   D D  IN++    H L  E  K      + + +  K 
Sbjct: 320 ESKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQ 379

Query: 220 PRT--QKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESK 277
            +    K      + P   L+ S +SS  E       S   +++ +   SN D+   +  
Sbjct: 380 EKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPET--SNSDMQTKKEY 437

Query: 278 GCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNER 318
               E  Q+ +  R +++  +  EN +LK      G++N R
Sbjct: 438 VVSGEHKQKGKVKRKLKNQNKNKENQELKQ--EKEGKENTR 476


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 38/161 (23%), Positives = 65/161 (40%), Gaps = 9/161 (5%)

Query: 163 EVPQILINREPLPHLHFDVELLGDCDVIINELC---HRLGGEYAKLCCNPVKLSEITEKP 219
           E  QIL ++ PLP    + E   D D  IN++    H L  E  K      + + +  K 
Sbjct: 343 ESKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQ 402

Query: 220 PRT--QKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESK 277
            +    K      + P   L+ S +SS  E       S   +++ +   SN D+   +  
Sbjct: 403 EKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPET--SNSDMQTKKEY 460

Query: 278 GCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNER 318
               E  Q+ +  R +++  +  EN +LK      G++N R
Sbjct: 461 VVSGEHKQKGKVKRKLKNQNKNKENQELKQ--EKEGKENTR 499


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 39/222 (17%)

Query: 210 VKLSEITEKPPRTQKELAYLSE-LPPTPLHVSED----------SSSPERTSPPDSSVIV 258
           VK S  +  PPR  +E   L +   P      E+          S S  +TS  +SS   
Sbjct: 215 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESS--- 271

Query: 259 TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNER 318
                +A+S    +  E +   EE+ +E  TS   E   E+ E  + +  GS++ E +E+
Sbjct: 272 -----SAESGSGSEEEEEEE--EEEEEEGSTSEESEEEEEEEEEEE-EETGSNSEEASEQ 323

Query: 319 TSVAGTVRKCWPNRVAKEQIS---RRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSS 375
           ++            V++E++S    R + N  L +P +R+     E   ++E++V   + 
Sbjct: 324 SA----------EEVSEEEMSEDEERENENHLLVVPESRFDRDSGE-SEEAEEEVGEGTP 372

Query: 376 CGSNSDSG--TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPE 415
             S    G     SP+L  P+E + E+ ++   L+    V E
Sbjct: 373 QSSALTEGDYVPDSPAL-SPIELKQELPKYLPALQGCRSVEE 413



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 364 SDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGF- 422
           SDSE    S+ S  + S SG+ +    EE  E+E    E     E+E +  E   G+   
Sbjct: 259 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 318

Query: 423 -GTDGDDQEAINEAISVKQEVTDMNY 447
             ++   +E   E +S  +E  + N+
Sbjct: 319 EASEQSAEEVSEEEMSEDEERENENH 344


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 39/222 (17%)

Query: 210 VKLSEITEKPPRTQKELAYLSE-LPPTPLHVSED----------SSSPERTSPPDSSVIV 258
           VK S  +  PPR  +E   L +   P      E+          S S  +TS  +SS   
Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESS--- 280

Query: 259 TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNER 318
                +A+S    +  E +   EE+ +E  TS   E   E+ E  + +  GS++ E +E+
Sbjct: 281 -----SAESGSGSEEEEEEE--EEEEEEGSTSEESEEEEEEEEEEE-EETGSNSEEASEQ 332

Query: 319 TSVAGTVRKCWPNRVAKEQIS---RRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSS 375
           ++            V++E++S    R + N  L +P +R+     E   ++E++V   + 
Sbjct: 333 SA----------EEVSEEEMSEDEERENENHLLVVPESRFDRDSGE-SEEAEEEVGEGTP 381

Query: 376 CGSNSDSG--TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPE 415
             S    G     SP+L  P+E + E+ ++   L+    V E
Sbjct: 382 QSSALTEGDYVPDSPAL-SPIELKQELPKYLPALQGCRSVEE 422



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 364 SDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGF- 422
           SDSE    S+ S  + S SG+ +    EE  E+E    E     E+E +  E   G+   
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 327

Query: 423 -GTDGDDQEAINEAISVKQEVTDMNY 447
             ++   +E   E +S  +E  + N+
Sbjct: 328 EASEQSAEEVSEEEMSEDEERENENH 353


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 39/222 (17%)

Query: 210 VKLSEITEKPPRTQKELAYLSE-LPPTPLHVSED----------SSSPERTSPPDSSVIV 258
           VK S  +  PPR  +E   L +   P      E+          S S  +TS  +SS   
Sbjct: 192 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESS--- 248

Query: 259 TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNER 318
                +A+S    +  E +   EE+ +E  TS   E   E+ E  + +  GS++ E +E+
Sbjct: 249 -----SAESGSGSEEEEEEE--EEEEEEGSTSEESEEEEEEEEEEE-EETGSNSEEASEQ 300

Query: 319 TSVAGTVRKCWPNRVAKEQIS---RRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSS 375
           ++            V++E++S    R + N  L +P +R+     E   ++E++V   + 
Sbjct: 301 SA----------EEVSEEEMSEDEERENENHLLVVPESRFDRDSGE-SEEAEEEVGEGTP 349

Query: 376 CGSNSDSG--TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPE 415
             S    G     SP+L  P+E + E+ ++   L+    V E
Sbjct: 350 QSSALTEGDYVPDSPAL-SPIELKQELPKYLPALQGCRSVEE 390



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 364 SDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGF- 422
           SDSE    S+ S  + S SG+ +    EE  E+E    E     E+E +  E   G+   
Sbjct: 236 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 295

Query: 423 -GTDGDDQEAINEAISVKQEVTDMNY 447
             ++   +E   E +S  +E  + N+
Sbjct: 296 EASEQSAEEVSEEEMSEDEERENENH 321


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 39/222 (17%)

Query: 210 VKLSEITEKPPRTQKELAYLSE-LPPTPLHVSED----------SSSPERTSPPDSSVIV 258
           VK S  +  PPR  +E   L +   P      E+          S S  +TS  +SS   
Sbjct: 181 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESS--- 237

Query: 259 TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNER 318
                +A+S    +  E +   EE+ +E  TS   E   E+ E  + +  GS++ E +E+
Sbjct: 238 -----SAESGSGSEEEEEEE--EEEEEEGSTSEESEEEEEEEEEEE-EETGSNSEEASEQ 289

Query: 319 TSVAGTVRKCWPNRVAKEQIS---RRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSS 375
           ++            V++E++S    R + N  L +P +R+     E   ++E++V   + 
Sbjct: 290 SA----------EEVSEEEMSEDEERENENHLLVVPESRFDRDSGE-SEEAEEEVGEGTP 338

Query: 376 CGSNSDSG--TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPE 415
             S    G     SP+L  P+E + E+ ++   L+    V E
Sbjct: 339 QSSALTEGDYVPDSPAL-SPIELKQELPKYLPALQGCRSVEE 379



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 364 SDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGF- 422
           SDSE    S+ S  + S SG+ +    EE  E+E    E     E+E +  E   G+   
Sbjct: 225 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 284

Query: 423 -GTDGDDQEAINEAISVKQEVTDMNY 447
             ++   +E   E +S  +E  + N+
Sbjct: 285 EASEQSAEEVSEEEMSEDEERENENH 310


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 32.7 bits (73), Expect = 0.69
 Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 39/222 (17%)

Query: 210 VKLSEITEKPPRTQKELAYLSE-LPPTPLHVSED----------SSSPERTSPPDSSVIV 258
           VK S  +  PPR  +E   L +   P      E+          S S  +TS  +SS   
Sbjct: 226 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESS--- 282

Query: 259 TLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNER 318
                +A+S    +  E +   EE+ +E  TS   E   E+ E  + +  GS++ E +E+
Sbjct: 283 -----SAESGSGSEEEEEEE--EEEEEEGSTSEESEEEEEEEEEEE-EETGSNSEEASEQ 334

Query: 319 TSVAGTVRKCWPNRVAKEQIS---RRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSS 375
           ++            V++E++S    R + N  L +P +R+     E   ++E++V   + 
Sbjct: 335 SA----------EEVSEEEMSEDEERENENHLLVVPESRFDRDSGE-SEEAEEEVGEGTP 383

Query: 376 CGSNSDSG--TCQSPSLEEPMEDESEIEEFYNGLEDEPDVPE 415
             S    G     SP+L  P+E + E+ ++   L+    V E
Sbjct: 384 QSSALTEGDYVPDSPAL-SPIELKQELPKYLPALQGCRSVEE 424



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 364 SDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGF- 422
           SDSE    S+ S  + S SG+ +    EE  E+E    E     E+E +  E   G+   
Sbjct: 270 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 329

Query: 423 -GTDGDDQEAINEAISVKQEVTDMNY 447
             ++   +E   E +S  +E  + N+
Sbjct: 330 EASEQSAEEVSEEEMSEDEERENENH 355


>gi|29789072 zinc finger, ZZ-type containing 3 [Homo sapiens]
          Length = 903

 Score = 32.3 bits (72), Expect = 0.90
 Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 15/120 (12%)

Query: 284 PQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGT-VRKCWPNRVA---KEQIS 339
           P+EV+ SR  + IA+++ N   K V S   +   + + AG  V    PN      K   S
Sbjct: 672 PEEVE-SRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSKKSSTS 730

Query: 340 RRLDG-NQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDES 398
           RR    N++LF P      H   VY D +DD     SC  +       + ++E+  +DES
Sbjct: 731 RRQHPLNKHLFKPSTFMTSHEPPVYMDEDDD----RSCFHSH-----MNTAVEDASDDES 781


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,316,497
Number of Sequences: 37866
Number of extensions: 960877
Number of successful extensions: 3215
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 3021
Number of HSP's gapped (non-prelim): 229
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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