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Search of human proteins with 21464115
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
(586 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 1259 0.0
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 1083 0.0
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s... 973 0.0
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 952 0.0
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo... 951 0.0
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 86 1e-16
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 86 1e-16
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 83 8e-16
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens] 76 8e-14
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens] 76 8e-14
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens] 74 4e-13
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 70 4e-12
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 55 1e-07
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 55 1e-07
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 55 2e-07
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 55 2e-07
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 54 3e-07
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 54 5e-07
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 54 5e-07
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 51 3e-06
gi|156139122 CXXC finger 6 [Homo sapiens] 42 0.002
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a... 41 0.003
gi|239752224 PREDICTED: hypothetical protein XP_002348163 [Homo ... 40 0.006
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 40 0.006
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 40 0.006
gi|153945850 doublesex and mab-3 related transcription factor 2 ... 40 0.006
gi|239755909 PREDICTED: hypothetical protein [Homo sapiens] 40 0.008
gi|239750423 PREDICTED: hypothetical protein XP_002347390 [Homo ... 40 0.008
gi|158261990 CXXC finger 5 [Homo sapiens] 40 0.008
gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens] 39 0.013
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 1259 bits (3257), Expect = 0.0
Identities = 586/586 (100%), Positives = 586/586 (100%)
Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
Query: 301 TEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 360
TEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK
Sbjct: 301 TEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 360
Query: 361 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 420
RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA
Sbjct: 361 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 420
Query: 421 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE 480
GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE
Sbjct: 421 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE 480
Query: 481 ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPSLQGRHSGREDGCKVWE 540
ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPSLQGRHSGREDGCKVWE
Sbjct: 481 ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPSLQGRHSGREDGCKVWE 540
Query: 541 TEDTVEPTSTSWNPRGWPGTHVSLSPPPASMMWVSCRRSWCPSSQS 586
TEDTVEPTSTSWNPRGWPGTHVSLSPPPASMMWVSCRRSWCPSSQS
Sbjct: 541 TEDTVEPTSTSWNPRGWPGTHVSLSPPPASMMWVSCRRSWCPSSQS 586
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 1083 bits (2800), Expect = 0.0
Identities = 523/592 (88%), Positives = 523/592 (88%), Gaps = 69/592 (11%)
Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
Query: 301 TEP-----------------------QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 337
TEP QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP
Sbjct: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360
Query: 338 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 397
KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420
Query: 398 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 457
LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480
Query: 458 LQ----------------------------------------------AVDPGLPSVKQE 471
LQ AVDPGLPSVKQE
Sbjct: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540
Query: 472 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 523
PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP
Sbjct: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 592
>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
sapiens]
Length = 503
Score = 973 bits (2515), Expect = 0.0
Identities = 471/523 (90%), Positives = 475/523 (90%), Gaps = 33/523 (6%)
Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
Query: 301 TEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 360
TEP P A +C D+ + +K
Sbjct: 301 TEPHP-------------RALAPSPPAEFIYYCVDEDE--------------------LK 327
Query: 361 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 420
RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA
Sbjct: 328 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 387
Query: 421 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE 480
GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE
Sbjct: 388 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE 447
Query: 481 ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 523
ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP
Sbjct: 448 ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 490
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 952 bits (2460), Expect = 0.0
Identities = 473/592 (79%), Positives = 474/592 (80%), Gaps = 118/592 (19%)
Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF--------- 171
Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
+SRGCGVCRGCQTQEDCGHC
Sbjct: 172 ----------------------------------------KSRGCGVCRGCQTQEDCGHC 191
Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 192 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 251
Query: 301 TEP-----------------------QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 337
TEP QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP
Sbjct: 252 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 311
Query: 338 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 397
KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 312 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 371
Query: 398 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 457
LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 372 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 431
Query: 458 LQ----------------------------------------------AVDPGLPSVKQE 471
LQ AVDPGLPSVKQE
Sbjct: 432 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 491
Query: 472 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 523
PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP
Sbjct: 492 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 543
>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
sapiens]
Length = 549
Score = 951 bits (2458), Expect = 0.0
Identities = 471/569 (82%), Positives = 475/569 (83%), Gaps = 79/569 (13%)
Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
Query: 301 TEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 360
TEP P A +C D+ + +K
Sbjct: 301 TEPHP-------------RALAPSPPAEFIYYCVDEDE--------------------LK 327
Query: 361 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 420
RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA
Sbjct: 328 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 387
Query: 421 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQ--------------------- 459
GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQ
Sbjct: 388 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKA 447
Query: 460 -------------------------AVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEE 494
AVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEE
Sbjct: 448 DTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEE 507
Query: 495 EAGGAGTPVITEIFSLGGTRFRDTAVWLP 523
EAGGAGTPVITEIFSLGGTRFRDTAVWLP
Sbjct: 508 EAGGAGTPVITEIFSLGGTRFRDTAVWLP 536
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 85.5 bits (210), Expect = 1e-16
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)
Query: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
+DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+
Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
Query: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
G K P + K++ + P K
Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
Length = 411
Score = 85.5 bits (210), Expect = 1e-16
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)
Query: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
+DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+
Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
Query: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
G K P + K++ + P K
Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 82.8 bits (203), Expect = 8e-16
Identities = 69/245 (28%), Positives = 107/245 (43%), Gaps = 29/245 (11%)
Query: 273 GCDSKMAARRRPGAQPLPPP-----PPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDC 327
G D K + A+PL PP P +++ P EP P R++R+CG C C DC
Sbjct: 1109 GNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEP-PVKKGRRSRRCGQCPGCQVPEDC 1167
Query: 328 GRCDFCCDKPKFGGSNQKRQKCRWRQC--LQFAMKR--LLPSVWSESEDGAGSPPPYRRR 383
G C C DKPKFGG N K+Q C+ R+C LQ+ + L + + S ++
Sbjct: 1168 GVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKD 1227
Query: 384 KRPSSARRHHLGPTLKPTLATR--------TAQPDHTQAPTKQEAGGGFVLPPPGTDLVF 435
+ SS ++ + + KPT + R +++P + ++ G P P +
Sbjct: 1228 SKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQAT 1287
Query: 436 L------REGASSPVQVPGPVAASTEALLQAVDPGLPS--VKQEPPDPEEDKEENKDDSA 487
+ S P V P +T + V PS K++PP PE E++K
Sbjct: 1288 TPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQ--- 1344
Query: 488 SKLAP 492
K+AP
Sbjct: 1345 KKVAP 1349
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 31/128 (24%)
Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG-------------------------LRRQW 255
RSR CG C GCQ EDCG C CL P+ G L++Q
Sbjct: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210
Query: 256 KCVQRRCLRGKHARRKGGCDSKMAARRRPGAQ-PLP-----PPPPSQSPEPTEPQPYTNR 309
K V+++ + K + +K +S + +Q P P P P S EP +P +
Sbjct: 1211 KAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEK 1270
Query: 310 RQNRKCGA 317
+ A
Sbjct: 1271 SEEGNVSA 1278
>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
Length = 660
Score = 76.3 bits (186), Expect = 8e-14
Identities = 58/185 (31%), Positives = 74/185 (40%), Gaps = 52/185 (28%)
Query: 253 RQWKCVQRRC----------LRGKHARRKGGCDSKMAARRRPGA---QPLPPPP------ 293
R+W C R C R K +R + G + + R G +P+P P
Sbjct: 66 REWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAG 123
Query: 294 -----------PSQSPEPTEPQPYTN-------------RRQNRKCGACAACLRRMDCGR 329
S SP + PQP +R R CG C AC R DCG
Sbjct: 124 SGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTEDCGH 183
Query: 330 CDFCCDKPKFGGSNQKRQKCRWRQC-------LQFAMKRLLPSVWSESEDGAGSPPPYRR 382
CDFC D KFGG N+ RQKCR RQC ++ L P SES P P ++
Sbjct: 184 CDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQ 243
Query: 383 RKRPS 387
+ +PS
Sbjct: 244 QPQPS 248
Score = 46.2 bits (108), Expect = 8e-05
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272
+I +R CG C C+ EDCGHC C + P RQ KC R+C LR + + +
Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219
Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302
+P P P Q P+P++
Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
++Q+ KR CGEC AC+ TEDCG C C + + KC R+C
Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208
>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
Length = 656
Score = 76.3 bits (186), Expect = 8e-14
Identities = 58/185 (31%), Positives = 74/185 (40%), Gaps = 52/185 (28%)
Query: 253 RQWKCVQRRC----------LRGKHARRKGGCDSKMAARRRPGA---QPLPPPP------ 293
R+W C R C R K +R + G + + R G +P+P P
Sbjct: 66 REWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAG 123
Query: 294 -----------PSQSPEPTEPQPYTN-------------RRQNRKCGACAACLRRMDCGR 329
S SP + PQP +R R CG C AC R DCG
Sbjct: 124 SGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTEDCGH 183
Query: 330 CDFCCDKPKFGGSNQKRQKCRWRQC-------LQFAMKRLLPSVWSESEDGAGSPPPYRR 382
CDFC D KFGG N+ RQKCR RQC ++ L P SES P P ++
Sbjct: 184 CDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQ 243
Query: 383 RKRPS 387
+ +PS
Sbjct: 244 QPQPS 248
Score = 46.2 bits (108), Expect = 8e-05
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272
+I +R CG C C+ EDCGHC C + P RQ KC R+C LR + + +
Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219
Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302
+P P P Q P+P++
Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
++Q+ KR CGEC AC+ TEDCG C C + + KC R+C
Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208
>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
Length = 291
Score = 73.9 bits (180), Expect = 4e-13
Identities = 32/61 (52%), Positives = 43/61 (70%)
Query: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQ 66
+CPAL GW+R EV R+SG + G D +Y SP+G + RSK +L RYLG + DL+ FDF+
Sbjct: 7 ECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFDFRT 66
Query: 67 G 67
G
Sbjct: 67 G 67
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 17/128 (13%)
Query: 295 SQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC 354
+ +P + P + + + +CG C CLR DCG C C DKPKFGG N K+Q C +R+C
Sbjct: 946 AHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKC 1005
Query: 355 LQF--------------AMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRH---HLGPT 397
+ +K LLP ES + + PP RR R H GP
Sbjct: 1006 DKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPE 1065
Query: 398 LKPTLATR 405
+ +L R
Sbjct: 1066 EQDSLLQR 1073
Score = 49.3 bits (116), Expect = 1e-05
Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 29/192 (15%)
Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRCLRGKHARRKGGCDSK 277
R CG CRGC +DCG C CL P+ P ++Q CV R+C K RK +
Sbjct: 962 RMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQC-CVYRKC--DKIEARK---MER 1015
Query: 278 MAARRRPGAQPLPPPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 337
+A + R + L P +SPE + P R GA A G + P
Sbjct: 1016 LAKKGRTIVKTLLPWDSDESPEASPGPPGPRR------GAGAG-------GPREEVVAHP 1062
Query: 338 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 397
+ Q+ R+C++ +R ++ +S+D PP RR+ P R + P
Sbjct: 1063 GPEEQDSLLQRKSARRCVK---QRPSYDIFEDSDDSEPGGPPAPRRRTP----RENELPL 1115
Query: 398 LKPTLATRTAQP 409
+P +R +P
Sbjct: 1116 PEPEEQSRPRKP 1127
Score = 32.0 bits (71), Expect = 1.6
Identities = 10/20 (50%), Positives = 12/20 (60%)
Query: 176 CGECAACQVTEDCGACSTCL 195
CG C C +DCG+C CL
Sbjct: 966 CGHCRGCLRVQDCGSCVNCL 985
Score = 30.8 bits (68), Expect = 3.6
Identities = 51/203 (25%), Positives = 69/203 (33%), Gaps = 56/203 (27%)
Query: 281 RRRPGAQPLPPPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFG 340
R P P PPPPP+ SP P P T+ R+ A P+F
Sbjct: 616 RELPPPPPAPPPPPAPSPPPA---PATSSRRPLLLRA-------------------PQFT 653
Query: 341 GSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPY----RRRKRPSSARRHHLG- 395
S L+ L P E PPP + + R +HL
Sbjct: 654 PSEAH---------LKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSL 704
Query: 396 PTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPV-AAST 454
P P + T P K E + P G L G + Q+ P+ A T
Sbjct: 705 PRFAPVVTT----------PVKAE------VSPHGAPA--LSNGPQTQAQLLQPLQALQT 746
Query: 455 EALLQAVDPGLPSVKQEPPDPEE 477
+ L QA+ P P + Q PP P++
Sbjct: 747 QLLPQALPPPQPQL-QPPPSPQQ 768
Score = 30.0 bits (66), Expect = 6.2
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 284 PGAQPLPPPPPSQSPEPTEPQPYTNRRQNRKCG 316
P P PPPPP+Q + P P +RK G
Sbjct: 438 PPPLPSPPPPPAQEEQEESPPPVVPATCSRKRG 470
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 55.5 bits (132), Expect = 1e-07
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 299 EPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFA 358
E + + N + R+CG C C ++ +CG+C C D KFGGS + +Q C+ R+C A
Sbjct: 653 EKDDREDKENAFKRRRCGVCEVC-QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMA 711
Query: 359 MK 360
MK
Sbjct: 712 MK 713
Score = 35.0 bits (79), Expect = 0.19
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 167 EQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
++ FKR CG C CQ E CG C C + + C+ RRC
Sbjct: 660 KENAFKRRRCGVCEVCQQPE-CGKCKACKDMVKFGGSGRSKQACQERRC 707
Score = 33.9 bits (76), Expect = 0.43
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG--LRRQWKCVQRRC 262
+ R CGVC CQ Q +CG C C + G R + C +RRC
Sbjct: 665 KRRRCGVCEVCQ-QPECGKCKACKDMVKFGGSGRSKQACQERRC 707
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 55.5 bits (132), Expect = 1e-07
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 299 EPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFA 358
E + + N + R+CG C C ++ +CG+C C D KFGGS + +Q C+ R+C A
Sbjct: 637 EKDDREDKENAFKRRRCGVCEVC-QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMA 695
Query: 359 MK 360
MK
Sbjct: 696 MK 697
Score = 35.0 bits (79), Expect = 0.19
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%)
Query: 167 EQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
++ FKR CG C CQ E CG C C + + C+ RRC
Sbjct: 644 KENAFKRRRCGVCEVCQQPE-CGKCKACKDMVKFGGSGRSKQACQERRC 691
Score = 33.9 bits (76), Expect = 0.43
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG--LRRQWKCVQRRC 262
+ R CGVC CQ Q +CG C C + G R + C +RRC
Sbjct: 649 KRRRCGVCEVCQ-QPECGKCKACKDMVKFGGSGRSKQACQERRC 691
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a
[Homo sapiens]
Length = 1336
Score = 55.1 bits (131), Expect = 2e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 309 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 355
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 607 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 652
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b
[Homo sapiens]
Length = 1265
Score = 55.1 bits (131), Expect = 2e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 309 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 355
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 576 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 621
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
sapiens]
Length = 694
Score = 54.3 bits (129), Expect = 3e-07
Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 277 KMAARRRPGAQPLPPPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDK 336
K+ + G L PP S S P RR+ R C C AC+R +CG C FC D
Sbjct: 4 KVPGKGESGPSALLTPPMSSSSRG--PGAGARRRRTR-CRRCRACVRT-ECGDCHFCRDM 59
Query: 337 PKFGGSNQKRQKCRWRQC 354
KFGG + +Q C RQC
Sbjct: 60 KKFGGPGRMKQSCLLRQC 77
Score = 38.9 bits (89), Expect = 0.013
Identities = 50/199 (25%), Positives = 67/199 (33%), Gaps = 49/199 (24%)
Query: 139 SFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACS----TC 194
S G G +R +T C+ CRA R CG+C C+ + G +C
Sbjct: 24 SSRGPGAGARRRRTRCRRCRA-----------CVRTECGDCHFCRDMKKFGGPGRMKQSC 72
Query: 195 LLQ------LPHDVASGLFCKCERRRCLRIVERSRG-----CGVCR-----GCQTQ---- 234
LL+ LPH L + + + E G C +C GC
Sbjct: 73 LLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFGLSLMECTICNEIVHPGCLKMGKAE 132
Query: 235 -------EDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQ 287
+C CP C + R +RR G+ G S P
Sbjct: 133 GVINAEIPNCWECPRCTQEGRTSKDSGEGPGRRRADNGEEGASLG---SGWKLTEEP--- 186
Query: 288 PLPPPPPS-QSPEPTEPQP 305
PLPPPPP + P P P P
Sbjct: 187 PLPPPPPRRKGPLPAGPPP 205
>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
Length = 498
Score = 53.5 bits (127), Expect = 5e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167
Query: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
DF P+ + KK K P P R R SG R +A E
Sbjct: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217
>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
Length = 486
Score = 53.5 bits (127), Expect = 5e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 96 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155
Query: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
DF P+ + KK K P P R R SG R +A E
Sbjct: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 51.2 bits (121), Expect = 3e-06
Identities = 26/67 (38%), Positives = 36/67 (53%), Gaps = 4/67 (5%)
Query: 292 PPPSQSP-EPTEPQPYTN--RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQK 348
P P +P P P + RR+ +C C AC++ +CG C +C D KFGG + +Q
Sbjct: 545 PAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQG-ECGVCHYCRDMKKFGGPGRMKQS 603
Query: 349 CRWRQCL 355
C RQCL
Sbjct: 604 CVLRQCL 610
>gi|156139122 CXXC finger 6 [Homo sapiens]
Length = 2136
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Query: 291 PPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCR 350
P + S T P +++ ++CG C C ++ +CG C +C ++ Q C+
Sbjct: 567 PMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQKTNCGECTYCKNR------KNSHQICK 620
Query: 351 WRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRK 384
R+C + K PSV E + P R +K
Sbjct: 621 KRKCEELKKK---PSVVVPLEVIKENKRPQREKK 651
Score = 32.7 bits (73), Expect = 0.95
Identities = 10/24 (41%), Positives = 15/24 (62%)
Query: 220 ERSRGCGVCRGCQTQEDCGHCPIC 243
++ + CGVC CQ + +CG C C
Sbjct: 586 KKRKRCGVCEPCQQKTNCGECTYC 609
Score = 31.6 bits (70), Expect = 2.1
Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 8/45 (17%)
Query: 172 KRVGCGECAACQVTEDCGACSTCL-LQLPHDVASGLFCKCERRRC 215
KR CG C CQ +CG C+ C + H + C++R+C
Sbjct: 587 KRKRCGVCEPCQQKTNCGECTYCKNRKNSHQI-------CKKRKC 624
>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
[Homo sapiens]
Length = 410
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/128 (25%), Positives = 43/128 (33%), Gaps = 4/128 (3%)
Query: 257 CVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPP--PPPSQSPEPTEPQPYTNRRQNRK 314
CV R G G + + A A P PP PPP P + + +
Sbjct: 237 CVVRFAKTGALRGAALGPPAALPAPLTEAAPPAPPARPPPGPGPSSAPAKASPEAEEAAR 296
Query: 315 CGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGA 374
C C A RR GR C + P G +R C W C + + L + D
Sbjct: 297 CVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLW--CAESLLYHCLSDAEGDFSDPC 354
Query: 375 GSPPPYRR 382
P + R
Sbjct: 355 ACEPGHPR 362
>gi|239752224 PREDICTED: hypothetical protein XP_002348163 [Homo
sapiens]
Length = 284
Score = 40.0 bits (92), Expect = 0.006
Identities = 58/221 (26%), Positives = 74/221 (33%), Gaps = 30/221 (13%)
Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDF 332
GC + RR P + P P + SP P T Q G A L + D G F
Sbjct: 41 GCQAP--PRRPPSSTPCPLL--TSSPSPLPSLLLTAAAQESAVGLLTASLLKGDSGSTGF 96
Query: 333 CCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDG-----AGSPPPYRRRKRPS 387
C Q+C C F KR S + + G G+ PP R RP
Sbjct: 97 CPLLMSLAAPG--TQQCSLGFCCTFERKRSSVSPAAPGKIGGVSLAVGAAPPPPRPNRPR 154
Query: 388 SARRHHLGPTLKPTLATRTAQ---PDHT------------QAPTKQEAGGGFVLPPPGTD 432
A R PT T A+ P HT ++P + AG +L G
Sbjct: 155 CAARGRPTPTRGSTRQRGGAERRSPGHTVTLYSSPGTVDSESPGRDGAGSPTILARAGVA 214
Query: 433 LVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPP 473
+SS +V G + S E LL EPP
Sbjct: 215 WTV----SSSCYRVEGALFGSCEVLLLPPGACTSPPGSEPP 251
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 40.0 bits (92), Expect = 0.006
Identities = 83/324 (25%), Positives = 118/324 (36%), Gaps = 50/324 (15%)
Query: 176 CGEC-----AACQVTEDC--GACSTCLLQLPHDVASGLFCKCERRRCL--RIVERSRGCG 226
CGE +AC V EDC C+ C ++ + + S CK C+ R V + G
Sbjct: 101 CGEQLGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKI----CIEQREVWKRSGAW 156
Query: 227 VCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKH-ARRKGGCDSKMAARRRPG 285
+G Q PI P+ + ++ KH AR DS+ RR PG
Sbjct: 157 FFKGFPKQVLPQPMPIKKTKPQQPVSEP-AAPEQPAPEPKHPARAPARGDSE--DRRGPG 213
Query: 286 AQPLPPPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQK 345
+ P P+ +P P R + + + D G +
Sbjct: 214 QKT--GPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSG----------GAGDSS 261
Query: 346 RQKCRWRQCLQFAMKRLLP-SVWSESEDGAGSP-PPYRRRKRPSSARRHHLGPTLKPTLA 403
R R+ R P SV S + G P P R P A R P KP +A
Sbjct: 262 RSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRF---PDQKPEVA 318
Query: 404 TRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDP 463
+ P T P ++ GG P G RE S GP + ++ A Q
Sbjct: 319 P--SDPGTTAPPREERTGGVGGYPAVGA-----REDRMS--HPSGPYSQASAAAPQ---- 365
Query: 464 GLPSVKQEPPDPEEDKEE-NKDDS 486
P+ ++PP PEE++EE N DS
Sbjct: 366 --PAAARQPPPPEEEEEEANSYDS 387
Score = 30.8 bits (68), Expect = 3.6
Identities = 36/139 (25%), Positives = 47/139 (33%), Gaps = 13/139 (9%)
Query: 369 ESEDGAGSPPPYRRRKRPSSAR-RHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLP 427
+SED G P + P+SA R + GP ++ R + G G
Sbjct: 205 DSEDRRG--PGQKTGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSR 262
Query: 428 PPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDP----EEDKEENK 483
P LR S P P + + A Q PG P + P P + K E
Sbjct: 263 SPAG----LRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 318
Query: 484 DDSASKLAP--EEEAGGAG 500
AP EE GG G
Sbjct: 319 PSDPGTTAPPREERTGGVG 337
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 40.0 bits (92), Expect = 0.006
Identities = 83/324 (25%), Positives = 118/324 (36%), Gaps = 50/324 (15%)
Query: 176 CGEC-----AACQVTEDC--GACSTCLLQLPHDVASGLFCKCERRRCL--RIVERSRGCG 226
CGE +AC V EDC C+ C ++ + + S CK C+ R V + G
Sbjct: 97 CGEQLGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKI----CIEQREVWKRSGAW 152
Query: 227 VCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKH-ARRKGGCDSKMAARRRPG 285
+G Q PI P+ + ++ KH AR DS+ RR PG
Sbjct: 153 FFKGFPKQVLPQPMPIKKTKPQQPVSEP-AAPEQPAPEPKHPARAPARGDSE--DRRGPG 209
Query: 286 AQPLPPPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQK 345
+ P P+ +P P R + + + D G +
Sbjct: 210 QKT--GPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSG----------GAGDSS 257
Query: 346 RQKCRWRQCLQFAMKRLLP-SVWSESEDGAGSP-PPYRRRKRPSSARRHHLGPTLKPTLA 403
R R+ R P SV S + G P P R P A R P KP +A
Sbjct: 258 RSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRF---PDQKPEVA 314
Query: 404 TRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDP 463
+ P T P ++ GG P G RE S GP + ++ A Q
Sbjct: 315 P--SDPGTTAPPREERTGGVGGYPAVGA-----REDRMS--HPSGPYSQASAAAPQ---- 361
Query: 464 GLPSVKQEPPDPEEDKEE-NKDDS 486
P+ ++PP PEE++EE N DS
Sbjct: 362 --PAAARQPPPPEEEEEEANSYDS 383
Score = 30.8 bits (68), Expect = 3.6
Identities = 36/139 (25%), Positives = 47/139 (33%), Gaps = 13/139 (9%)
Query: 369 ESEDGAGSPPPYRRRKRPSSAR-RHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLP 427
+SED G P + P+SA R + GP ++ R + G G
Sbjct: 201 DSEDRRG--PGQKTGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSR 258
Query: 428 PPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDP----EEDKEENK 483
P LR S P P + + A Q PG P + P P + K E
Sbjct: 259 SPAG----LRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 314
Query: 484 DDSASKLAP--EEEAGGAG 500
AP EE GG G
Sbjct: 315 PSDPGTTAPPREERTGGVG 333
>gi|153945850 doublesex and mab-3 related transcription factor 2
isoform 2 [Homo sapiens]
Length = 561
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/171 (24%), Positives = 59/171 (34%), Gaps = 38/171 (22%)
Query: 282 RRPGAQPLPPPPPSQSPEPTEPQ----PYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 337
+R G QP PP P SP T P+ P + RK C R + G
Sbjct: 80 QRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHK 139
Query: 338 KFGGSNQKRQKCRWRQC----------------LQFAMKRLLPSVWSESEDGAGSPPPYR 381
+F CRWR C Q A++R +ED G
Sbjct: 140 RF---------CRWRDCQCANCLLVVERQRVMAAQVALRRQ-----QATEDKKGLSGKQN 185
Query: 382 RRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD 432
+R + +R P+L ++ + P + GG F LPPP +D
Sbjct: 186 NFERKAVYQRQ----VRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSD 232
>gi|239755909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 212
Score = 39.7 bits (91), Expect = 0.008
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 244 LRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDS-KMAARRRPGAQPLPPPPPSQSPEPTE 302
L P R+ W+ ++R+C + + +GG S ++ A RPGA P S
Sbjct: 74 LGSPAERRRKMWRRLRRKCWKEQGPGGRGGASSSELRALGRPGAAGPGPGSGDASALAGG 133
Query: 303 PQPYTNRRQNRKCGACAACLR 323
P+P + + + GAC C R
Sbjct: 134 PRPVSRDTSSARSGACCGCSR 154
>gi|239750423 PREDICTED: hypothetical protein XP_002347390 [Homo
sapiens]
Length = 212
Score = 39.7 bits (91), Expect = 0.008
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 244 LRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDS-KMAARRRPGAQPLPPPPPSQSPEPTE 302
L P R+ W+ ++R+C + + +GG S ++ A RPGA P S
Sbjct: 74 LGSPAERRRKMWRRLRRKCWKEQGPGGRGGASSSELRALGRPGAAGPGPGSGDASALAGG 133
Query: 303 PQPYTNRRQNRKCGACAACLR 323
P+P + + + GAC C R
Sbjct: 134 PRPVSRDTSSARSGACCGCSR 154
>gi|158261990 CXXC finger 5 [Homo sapiens]
Length = 322
Score = 39.7 bits (91), Expect = 0.008
Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 6/54 (11%)
Query: 307 TNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 360
+ +++ ++CG CA C RR++C +C C ++ K G Q C++R+C + K
Sbjct: 255 SGKKKRKRCGMCAPCRRRINCEQCSSCRNR-KTG-----HQICKFRKCEELKKK 302
Score = 30.0 bits (66), Expect = 6.2
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 172 KRVGCGECAACQVTEDCGACSTCL-LQLPHDVASGLFCKCE 211
KR CG CA C+ +C CS+C + H + F KCE
Sbjct: 259 KRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICK--FRKCE 297
>gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
Length = 580
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 14 GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65
GW+R R G T GR D Y+ SP G + RSK L YL + +L FDF K
Sbjct: 89 GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148
Query: 66 QGI 68
+GI
Sbjct: 149 RGI 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,683,071
Number of Sequences: 37866
Number of extensions: 2006066
Number of successful extensions: 19620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 269
Number of HSP's that attempted gapping in prelim test: 16852
Number of HSP's gapped (non-prelim): 2631
length of query: 586
length of database: 18,247,518
effective HSP length: 108
effective length of query: 478
effective length of database: 14,157,990
effective search space: 6767519220
effective search space used: 6767519220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.