Guide to the Human Genome
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Search of human proteins with 21389577

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389577 hypothetical protein LOC146705 [Homo sapiens]
         (525 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389577 hypothetical protein LOC146705 [Homo sapiens]            1058   0.0  
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              48   2e-05
gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]                48   3e-05
gi|71043876 undifferentiated embryonic cell transcription factor...    48   3e-05
gi|47825361 non-specific cytotoxic cell receptor protein 1 homol...    48   3e-05
gi|33286446 opioid growth factor receptor [Homo sapiens]               47   3e-05
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       47   3e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       47   3e-05
gi|133922582 zinc finger protein 358 [Homo sapiens]                    47   4e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    47   6e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    47   6e-05
gi|119943102 CREB binding protein isoform b [Homo sapiens]             47   6e-05
gi|119943104 CREB binding protein isoform a [Homo sapiens]             47   6e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   6e-05
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]             46   7e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   7e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    46   7e-05
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    46   7e-05
gi|33356148 formin-like 1 [Homo sapiens]                               46   7e-05
gi|4503519 eukaryotic translation initiation factor 3, subunit 5...    45   1e-04
gi|116256475 zinc finger protein 827 [Homo sapiens]                    45   1e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   45   2e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   45   2e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   45   2e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    45   2e-04
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             45   2e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                45   2e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                45   2e-04
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                45   2e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    44   4e-04

>gi|21389577 hypothetical protein LOC146705 [Homo sapiens]
          Length = 525

 Score = 1058 bits (2735), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 1   MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSSQCLLEYLLSR 60
           MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSSQCLLEYLLSR
Sbjct: 1   MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSSQCLLEYLLSR 60

Query: 61  LHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQEAAAFAGPPDPLHGNSLYQKV 120
           LHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQEAAAFAGPPDPLHGNSLYQKV
Sbjct: 61  LHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQEAAAFAGPPDPLHGNSLYQKV 120

Query: 121 RAAAQDLGSTLFSDTVLPLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQ 180
           RAAAQDLGSTLFSDTVLPLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQ
Sbjct: 121 RAAAQDLGSTLFSDTVLPLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQ 180

Query: 181 PGQAGGGWDELDSGPSSQNSSQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVAL 240
           PGQAGGGWDELDSGPSSQNSSQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVAL
Sbjct: 181 PGQAGGGWDELDSGPSSQNSSQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVAL 240

Query: 241 SDCQQELSLVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRA 300
           SDCQQELSLVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRA
Sbjct: 241 SDCQQELSLVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRA 300

Query: 301 LCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARG 360
           LCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARG
Sbjct: 301 LCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARG 360

Query: 361 TSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPP 420
           TSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPP
Sbjct: 361 TSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPP 420

Query: 421 DASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACP 480
           DASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACP
Sbjct: 421 DASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACP 480

Query: 481 RLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFAFLNA 525
           RLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFAFLNA
Sbjct: 481 RLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFAFLNA 525


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 56/187 (29%), Positives = 73/187 (39%), Gaps = 33/187 (17%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLTDAVPL--PGSQVFLQPLSSTPVSSRSPAPSSGMPSS 413
           +PA    A P   A +PGP    TDA P   P  Q  L PL  +PV S+  +P    P S
Sbjct: 681 NPAAPALAAP---AVVPGPVST-TDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPS 736

Query: 414 PVPTPPPDASP---IPAPGDPSEAEARLAESRRWRPERIPGGTDS---------PKRGPS 461
             P PPP   P   + AP     AE  L +   W P   P   +          P+    
Sbjct: 737 YHPPPPPTKKPEVVVEAPSASETAEEPL-QDPNWPPPPPPAPEEQDLSMADFPPPEEAFF 795

Query: 462 SCAWSRDSLFAGM-ELVACPRLVGAGAAAGE----SCPDAPRAPQTSSQRTAA------- 509
           S A    +  +G  ELV+ P    + A A +      PD P AP   +  ++A       
Sbjct: 796 SVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKL 855

Query: 510 --KEPPG 514
             KEP G
Sbjct: 856 PQKEPVG 862



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 45/194 (23%), Positives = 68/194 (35%), Gaps = 44/194 (22%)

Query: 349 EASCGQLSPARGTSAEPGPTAAL------------------PGPSDLLTDAVPLPGSQVF 390
           +   G+ SP+ G++AE   T ++                  P P    T ++   G  V 
Sbjct: 456 QGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVP 515

Query: 391 LQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIP 450
             PL   P   R   P   +P  P       A   P P +P+ +         W P   P
Sbjct: 516 DGPLGLPPKPERKQQPQ--LPRPPTTGGSEGAGAAPCPPNPANS---------WVPGLSP 564

Query: 451 GGTDSPKRGPS-----SCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQ 505
           GG+  P R P      S  +S  S   G   +    L G  A+ G++ P  P       +
Sbjct: 565 GGSRRPPRSPERTLSPSSGYSSQS---GTPTLPPKGLAGPPASPGKAQPPKP-------E 614

Query: 506 RTAAKEPPGSEPSA 519
           R  +   PG+  S+
Sbjct: 615 RVTSLRSPGASVSS 628



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 60/240 (25%), Positives = 77/240 (32%), Gaps = 56/240 (23%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAA----------LPGPSD-LLTDAV 382
           P P T K   ++    AS     P +  +  P P  A           P P +   + A 
Sbjct: 740 PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVAS 799

Query: 383 PLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAP-------------- 428
           P P        L S+P +S S A +  +     P PPP A P PAP              
Sbjct: 800 PEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP-APPAPAPASSAPGHVAKLPQK 858

Query: 429 ---------GDPSE------AEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAG 473
                    G P E          L +  R R    PGG  +P  GPS+         +G
Sbjct: 859 EPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSG 918

Query: 474 ME---------LVACPRLVGAGAAAGESCPDA-PRAPQTSSQRTAAKEPPGSEPSAFAFL 523
                      L A  RL     AA E    A P  P  +  R     PP S  S  +F+
Sbjct: 919 RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPR-----PPQSPASTASFI 973



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 12/138 (8%)

Query: 333 SPG----PVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDL--LTDAVPLPG 386
           SPG    P   + T +     +    L+    +S++P P+    GP  L  L D   +P 
Sbjct: 604 SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDR-SGPQILTPLGDRFVIPP 662

Query: 387 SQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPP----DASPIPAPGDPSEAEARLAESR 442
                 P S  P   RSP P++   ++P   P P    DASP  +P  P      L ES 
Sbjct: 663 HPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASP-QSPPTPQTTLTPLQESP 721

Query: 443 RWRPERIPGGTDSPKRGP 460
               ++ P  +  P   P
Sbjct: 722 VISKDQSPPPSPPPSYHP 739



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 48/175 (27%), Positives = 72/175 (41%), Gaps = 19/175 (10%)

Query: 345  LRHFEASCGQLSPARGTSAEPGPTA-ALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRS 403
            LR   A  G  +PA G SA   P   AL G +      VP P S +     ++  + + S
Sbjct: 889  LRSVGAPGGAPTPALGPSAPQKPLRRALSGRAS----PVPAPSSGLH----AAVRLKACS 940

Query: 404  PAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAE-SRRWRPERIPGGTDSPKRGPSS 462
             A S G+ SS  P  PP+A P P     S A    ++ SR+ + ER           P +
Sbjct: 941  LAASEGL-SSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLER--------PVSPET 991

Query: 463  CAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEP 517
             A  + +L A +  ++  R   A   + ++ P   R P       A+   P +EP
Sbjct: 992  QADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP 1046


>gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]
          Length = 575

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 16/107 (14%)

Query: 357 PARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS----GMPS 412
           P     ++PGP     GP +L    +P+   QV  + + S PVS + P PS      +P 
Sbjct: 317 PENKPESKPGPV----GP-ELPPGHIPI---QVIRKEVDSKPVSQKPPPPSEKVEVKVPP 368

Query: 413 SPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRG 459
           +PVP PPP   P   P  P      +A   R  P   P     PK G
Sbjct: 369 APVPCPPPSPGPSAVPSSPKS----VATEERAAPSTAPAEATPPKPG 411


>gi|71043876 undifferentiated embryonic cell transcription factor 1
           [Homo sapiens]
          Length = 341

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 43/151 (28%), Positives = 57/151 (37%), Gaps = 37/151 (24%)

Query: 334 PGPVTNKATKIL---------RHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPL 384
           PGP   +  K++         R    S G   P R  +  P P A  P PS+   DA PL
Sbjct: 133 PGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQR--ARRPVPNAHAPAPSE--PDATPL 188

Query: 385 PGSQ------VFLQPLSSTPVSSRSPAPSSGMPSSPVPTP-----PPDASPIPAPGDPSE 433
           P ++       +    S +P  S   +P+ G P +P PT      P D +P+  PG P  
Sbjct: 189 PTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPP 248

Query: 434 AEARLAESRRWRPERIPGGTDSPKRGPSSCA 464
             AR                DSP   P  CA
Sbjct: 249 PPAR-------------EDPDSPPGRPEDCA 266


>gi|47825361 non-specific cytotoxic cell receptor protein 1 homolog
           [Homo sapiens]
          Length = 275

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 11/72 (15%)

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPP-------PDASPIPAPGDPSEAEARLAESRRWRP 446
           L   P S RSP+P    P  P+P+PP       P+A  +P P  PSEA AR      W P
Sbjct: 22  LQELPPSPRSPSPPPSPP--PLPSPPSLPSPAAPEAPELPEPAQPSEAHARQLLLEEWGP 79

Query: 447 ERIPGGTDSPKR 458
             + GG + P+R
Sbjct: 80  --LSGGLELPQR 89


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 46/167 (27%), Positives = 62/167 (37%), Gaps = 11/167 (6%)

Query: 353 GQLSPARGT----SAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRS--PAP 406
           G+  P  GT    S  PGP+ A P   +        PG +    P    P  S S  P P
Sbjct: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSETPGP 564

Query: 407 SSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGT--DSPKRGPSSCA 464
               P+   P   P  +P P+P  P+  E   AES    P   P G   D P   PS   
Sbjct: 565 RPAGPAGDEPAESPSETPGPSPAGPTRDEP--AESPSETPGPRPAGPAGDEPAESPSETP 622

Query: 465 WSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKE 511
             R +  AG E    P      + AG +  +  +A + +  + A  E
Sbjct: 623 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVE 669


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 51/166 (30%), Positives = 62/166 (37%), Gaps = 38/166 (22%)

Query: 362  SAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPS--SPVPTPP 419
            SA PGP A LP P+         PG      P SS P    S  P+ G+P+  +P P   
Sbjct: 931  SATPGPAAPLPSPT---------PGES---PPASSLPQPEPSSLPAQGVPTPLAPSPAMQ 978

Query: 420  PDASPIPAPGDPSEAEARLAESRRWRPE-----------RIPGGTDSPKRGPSSC---AW 465
            P   P P PG  S A      + RW  E           ++PG   +PK    +C   A+
Sbjct: 979  PPVPPCPGPGLESSA------ASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAF 1032

Query: 466  SRDSLF--AGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
            S   L    G   V  PR    G           R  QTSS   AA
Sbjct: 1033 SGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQ--RLEQTSSSLAAA 1076



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 46/185 (24%), Positives = 66/185 (35%), Gaps = 35/185 (18%)

Query: 354 QLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSS 413
           +LS   G S EP P    PGP +  T     P  +   +P   +      PAP+     +
Sbjct: 793 RLSSVSGPSPEPPPLDESPGPKEGATG----PRRRTLSEPAGPSEPPG-PPAPAGPASDT 847

Query: 414 PVPTPPPDASPIPAPGDPSEA-----EARLAESRRWRP-------ERIPGG-------TD 454
               P P+ +P P+ G   E      E  L   +R +P         +P G       +D
Sbjct: 848 EEEEPGPEGTP-PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESD 906

Query: 455 SPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPG 514
           + KR P      R+ L           L+  G A+    P AP    T  +   A   P 
Sbjct: 907 TVKRRPK--CREREPLQTA--------LLAFGVASATPGPAAPLPSPTPGESPPASSLPQ 956

Query: 515 SEPSA 519
            EPS+
Sbjct: 957 PEPSS 961



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 38/127 (29%), Positives = 49/127 (38%), Gaps = 9/127 (7%)

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGT 453
           L S    +R P  S+ + +SP  TP       PA G P  +++    +RR  P   P   
Sbjct: 741 LGSYATLTRRPGRSALVRTSPSVTPT------PARGTP-RSQSFALRARRKGPPPPPPKR 793

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKE-- 511
            S   GPS      D      E    PR       AG S P  P AP   +  T  +E  
Sbjct: 794 LSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPG 853

Query: 512 PPGSEPS 518
           P G+ PS
Sbjct: 854 PEGTPPS 860



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 30/109 (27%), Positives = 35/109 (32%), Gaps = 33/109 (30%)

Query: 360 GTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPP 419
           GT   P   ++LPG           P   VF+ P               G PSSP P PP
Sbjct: 653 GTERPPKLCSSLPGQG---------PPPYVFMYP--------------QGSPSSPAPGPP 689

Query: 420 PD--------ASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGP 460
           P         A P   P DP   + R       RP    G  +    GP
Sbjct: 690 PGAPWAFSYLAGPPATPPDPPRPKRR--SHSLSRPGPTEGDAEGEAEGP 736


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 51/166 (30%), Positives = 62/166 (37%), Gaps = 38/166 (22%)

Query: 362  SAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPS--SPVPTPP 419
            SA PGP A LP P+         PG      P SS P    S  P+ G+P+  +P P   
Sbjct: 1013 SATPGPAAPLPSPT---------PGES---PPASSLPQPEPSSLPAQGVPTPLAPSPAMQ 1060

Query: 420  PDASPIPAPGDPSEAEARLAESRRWRPE-----------RIPGGTDSPKRGPSSC---AW 465
            P   P P PG  S A      + RW  E           ++PG   +PK    +C   A+
Sbjct: 1061 PPVPPCPGPGLESSA------ASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAF 1114

Query: 466  SRDSLF--AGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
            S   L    G   V  PR    G           R  QTSS   AA
Sbjct: 1115 SGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQ--RLEQTSSSLAAA 1158



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 46/185 (24%), Positives = 66/185 (35%), Gaps = 35/185 (18%)

Query: 354  QLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSS 413
            +LS   G S EP P    PGP +  T     P  +   +P   +      PAP+     +
Sbjct: 875  RLSSVSGPSPEPPPLDESPGPKEGATG----PRRRTLSEPAGPSEPPG-PPAPAGPASDT 929

Query: 414  PVPTPPPDASPIPAPGDPSEA-----EARLAESRRWRP-------ERIPGG-------TD 454
                P P+ +P P+ G   E      E  L   +R +P         +P G       +D
Sbjct: 930  EEEEPGPEGTP-PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESD 988

Query: 455  SPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPG 514
            + KR P      R+ L           L+  G A+    P AP    T  +   A   P 
Sbjct: 989  TVKRRPK--CREREPLQTA--------LLAFGVASATPGPAAPLPSPTPGESPPASSLPQ 1038

Query: 515  SEPSA 519
             EPS+
Sbjct: 1039 PEPSS 1043



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 38/127 (29%), Positives = 49/127 (38%), Gaps = 9/127 (7%)

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGT 453
           L S    +R P  S+ + +SP  TP       PA G P  +++    +RR  P   P   
Sbjct: 823 LGSYATLTRRPGRSALVRTSPSVTPT------PARGTP-RSQSFALRARRKGPPPPPPKR 875

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKE-- 511
            S   GPS      D      E    PR       AG S P  P AP   +  T  +E  
Sbjct: 876 LSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPG 935

Query: 512 PPGSEPS 518
           P G+ PS
Sbjct: 936 PEGTPPS 942



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 30/109 (27%), Positives = 35/109 (32%), Gaps = 33/109 (30%)

Query: 360 GTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPP 419
           GT   P   ++LPG           P   VF+ P               G PSSP P PP
Sbjct: 735 GTERPPKLCSSLPGQG---------PPPYVFMYP--------------QGSPSSPAPGPP 771

Query: 420 PD--------ASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGP 460
           P         A P   P DP   + R       RP    G  +    GP
Sbjct: 772 PGAPWAFSYLAGPPATPPDPPRPKRR--SHSLSRPGPTEGDAEGEAEGP 818


>gi|133922582 zinc finger protein 358 [Homo sapiens]
          Length = 568

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 44/163 (26%), Positives = 63/163 (38%), Gaps = 30/163 (18%)

Query: 324 PWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAA---LPGPSDLLTD 380
           P L   SM  PG V+      +    +  G LSP   +   P P +    LP PS     
Sbjct: 422 PGLSPASMMRPGQVSLLGPDAVSVLGSGLG-LSPGTSSGRNPDPGSGPGTLPDPS----- 475

Query: 381 AVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAE 440
           + PLPGS+    P   TPV S  P   +G  + P   P PD  P+P+P            
Sbjct: 476 SKPLPGSRSTPSP---TPVESSDP--KAGHDAGPDLVPSPDLDPVPSPD----------- 519

Query: 441 SRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLV 483
                P+ +P    +P   P  C+ +R ++   +     P  V
Sbjct: 520 -----PDPVPSPDPNPVSCPDPCSPTRGTVSPALPTGESPEWV 557



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 55/226 (24%), Positives = 78/226 (34%), Gaps = 33/226 (14%)

Query: 302 CAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGT 361
           C+ A   SS LL   H+    RP+  +L     G    +A+ + +H     G  + A   
Sbjct: 352 CSKAFGQSSALLQHLHVHSGERPYRCQLC----GKAFGQASSLTKHKRVHEGAAAAAAAA 407

Query: 362 SAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPD 421
           +A     AA  G    L+ A  +   QV L    +  V       S G  S   P P   
Sbjct: 408 AAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLGSGLGLSPGTSSGRNPDPGSG 467

Query: 422 ASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPR 481
              +P   DPS              + +PG   +P   P   +  +    AG +LV  P 
Sbjct: 468 PGTLP---DPSS-------------KPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSPD 511

Query: 482 L----------VGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEP 517
           L          V +      SCPD P +P   +   A   P G  P
Sbjct: 512 LDPVPSPDPDPVPSPDPNPVSCPD-PCSPTRGTVSPAL--PTGESP 554


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 43/145 (29%), Positives = 56/145 (38%), Gaps = 11/145 (7%)

Query: 323 RPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAV 382
           RP +   ++  P P  NK         ++  Q  P     + PGP    P  S    D  
Sbjct: 274 RPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG--NDET 331

Query: 383 P-LPGSQVFLQ----PLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSE--AE 435
           P LP   + L     PL S   S   P P S  P  PV  PP  + P+P P   S   + 
Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGST 391

Query: 436 ARLAESRRWRPERIPGGTDSPKRGP 460
           +R   +    P R   G DSP+ GP
Sbjct: 392 SRALPATPQLPSR--SGVDSPRSGP 414



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 53/189 (28%), Positives = 73/189 (38%), Gaps = 35/189 (18%)

Query: 356 SPARGTSAEPGPTAALPG--PSDLLTDAVPLPGSQVFLQPLSSTP---VSSRSPAPSSGM 410
           +P+R    +P P     G  PS +  +AVP P  Q    P+ STP    SS++P P    
Sbjct: 255 TPSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPP-P 312

Query: 411 PSSPVPTPPPDAS---------------------PIPAPGDPSEAEARLAESRRWRPERI 449
           PS P P P P +S                     P+P+PG         +E R   P R 
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE-RPPPPVRD 371

Query: 450 PGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
           P G   P   P   + +  +  A   L A P+L    + +G   P +   P     R +A
Sbjct: 372 PPGRSGPLPPPPPVSRNGSTSRA---LPATPQL---PSRSGVDSPRSGPRPPLPPDRPSA 425

Query: 510 KEPPGSEPS 518
             PP   PS
Sbjct: 426 GAPPPPPPS 434



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 38/151 (25%), Positives = 55/151 (36%), Gaps = 24/151 (15%)

Query: 382 VPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSP-------VPTP------PPDASPIPAP 428
           +P  G     +P S      R P PS G  S P       +P P       PD+ P P P
Sbjct: 129 LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188

Query: 429 GDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAW--SRDSLFAGMELVACPRLVGAG 486
             P   ++  +   R  P  +PGG   P  GP+   +  +R +   G  +   P      
Sbjct: 189 STPRPIQS--SPHNRGSPP-VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP------ 239

Query: 487 AAAGESCPDAPRAPQTSSQRTAAKEPPGSEP 517
            ++     + P  P T S+    K PP   P
Sbjct: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 27/89 (30%), Positives = 36/89 (40%), Gaps = 10/89 (11%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPL-------SSTPVSSRSPAPSS 408
           SP   +S         P PS  L D  P P   V  +P           P +++ P PS+
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297

Query: 409 GMPSS---PVPTPPPDASPIPAPGDPSEA 434
             PS+     P PPP + P P P  PS +
Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSS 326



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 22/80 (27%), Positives = 30/80 (37%), Gaps = 1/80 (1%)

Query: 351 SCGQLSPARGTSAEPGPTAA-LPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSG 409
           S    SP  G    P P+     GP +   + +P P   V  +P S  P    +P P   
Sbjct: 137 SAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQS 196

Query: 410 MPSSPVPTPPPDASPIPAPG 429
            P +    P P     P+PG
Sbjct: 197 SPHNRGSPPVPGGPRQPSPG 216


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 43/145 (29%), Positives = 56/145 (38%), Gaps = 11/145 (7%)

Query: 323 RPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAV 382
           RP +   ++  P P  NK         ++  Q  P     + PGP    P  S    D  
Sbjct: 274 RPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG--NDET 331

Query: 383 P-LPGSQVFLQ----PLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSE--AE 435
           P LP   + L     PL S   S   P P S  P  PV  PP  + P+P P   S   + 
Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGST 391

Query: 436 ARLAESRRWRPERIPGGTDSPKRGP 460
           +R   +    P R   G DSP+ GP
Sbjct: 392 SRALPATPQLPSR--SGVDSPRSGP 414



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 53/189 (28%), Positives = 73/189 (38%), Gaps = 35/189 (18%)

Query: 356 SPARGTSAEPGPTAALPG--PSDLLTDAVPLPGSQVFLQPLSSTP---VSSRSPAPSSGM 410
           +P+R    +P P     G  PS +  +AVP P  Q    P+ STP    SS++P P    
Sbjct: 255 TPSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPP-P 312

Query: 411 PSSPVPTPPPDAS---------------------PIPAPGDPSEAEARLAESRRWRPERI 449
           PS P P P P +S                     P+P+PG         +E R   P R 
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE-RPPPPVRD 371

Query: 450 PGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
           P G   P   P   + +  +  A   L A P+L    + +G   P +   P     R +A
Sbjct: 372 PPGRSGPLPPPPPVSRNGSTSRA---LPATPQL---PSRSGVDSPRSGPRPPLPPDRPSA 425

Query: 510 KEPPGSEPS 518
             PP   PS
Sbjct: 426 GAPPPPPPS 434



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 38/151 (25%), Positives = 55/151 (36%), Gaps = 24/151 (15%)

Query: 382 VPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSP-------VPTP------PPDASPIPAP 428
           +P  G     +P S      R P PS G  S P       +P P       PD+ P P P
Sbjct: 129 LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188

Query: 429 GDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAW--SRDSLFAGMELVACPRLVGAG 486
             P   ++  +   R  P  +PGG   P  GP+   +  +R +   G  +   P      
Sbjct: 189 STPRPIQS--SPHNRGSPP-VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP------ 239

Query: 487 AAAGESCPDAPRAPQTSSQRTAAKEPPGSEP 517
            ++     + P  P T S+    K PP   P
Sbjct: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 27/89 (30%), Positives = 36/89 (40%), Gaps = 10/89 (11%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPL-------SSTPVSSRSPAPSS 408
           SP   +S         P PS  L D  P P   V  +P           P +++ P PS+
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297

Query: 409 GMPSS---PVPTPPPDASPIPAPGDPSEA 434
             PS+     P PPP + P P P  PS +
Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSS 326



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 22/80 (27%), Positives = 30/80 (37%), Gaps = 1/80 (1%)

Query: 351 SCGQLSPARGTSAEPGPTAA-LPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSG 409
           S    SP  G    P P+     GP +   + +P P   V  +P S  P    +P P   
Sbjct: 137 SAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQS 196

Query: 410 MPSSPVPTPPPDASPIPAPG 429
            P +    P P     P+PG
Sbjct: 197 SPHNRGSPPVPGGPRQPSPG 216


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 49/170 (28%), Positives = 69/170 (40%), Gaps = 22/170 (12%)

Query: 365  PGPTAALPGP--SDLLTDAVPLPGSQVFLQPLSSTPVS----SRSPAP---SSGMPSSPV 415
            P PT+A PG       T   P P +Q    P+S +P      +R+  P   S+G P+S V
Sbjct: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1904

Query: 416  PTPPPDASPIPAPGDPSEAEARLAESRR----------WRPERIPGGTDSPKRGPSSCAW 465
            P PPP A P PA  + +    R A+ ++            P R   GT   +  P S   
Sbjct: 1905 PAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNV 1964

Query: 466  SRDSLFAGMELVACP--RLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPP 513
             R +  +G  + + P  +   A     +  P  PR P  S Q  AA   P
Sbjct: 1965 PRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQAQAAVAGP 2013



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 36/105 (34%), Positives = 45/105 (42%), Gaps = 5/105 (4%)

Query: 353 GQLSPARGTSAEPGPTAALPGPSDLL-TDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMP 411
           GQ     G S    P AALP P ++L   A  LP   V   PL  TP  + + A   GMP
Sbjct: 773 GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAA---GMP 829

Query: 412 SSPVPTPPPDASPIP-APGDPSEAEARLAESRRWRPERIPGGTDS 455
           S    TPP    P P AP  PS   +   ++    P  +P  T +
Sbjct: 830 SLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 49/170 (28%), Positives = 69/170 (40%), Gaps = 22/170 (12%)

Query: 365  PGPTAALPGP--SDLLTDAVPLPGSQVFLQPLSSTPVS----SRSPAP---SSGMPSSPV 415
            P PT+A PG       T   P P +Q    P+S +P      +R+  P   S+G P+S V
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1942

Query: 416  PTPPPDASPIPAPGDPSEAEARLAESRR----------WRPERIPGGTDSPKRGPSSCAW 465
            P PPP A P PA  + +    R A+ ++            P R   GT   +  P S   
Sbjct: 1943 PAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNV 2002

Query: 466  SRDSLFAGMELVACP--RLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPP 513
             R +  +G  + + P  +   A     +  P  PR P  S Q  AA   P
Sbjct: 2003 PRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQAQAAVAGP 2051



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 36/105 (34%), Positives = 45/105 (42%), Gaps = 5/105 (4%)

Query: 353 GQLSPARGTSAEPGPTAALPGPSDLL-TDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMP 411
           GQ     G S    P AALP P ++L   A  LP   V   PL  TP  + + A   GMP
Sbjct: 811 GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAA---GMP 867

Query: 412 SSPVPTPPPDASPIP-APGDPSEAEARLAESRRWRPERIPGGTDS 455
           S    TPP    P P AP  PS   +   ++    P  +P  T +
Sbjct: 868 SLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 912


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 57/211 (27%), Positives = 74/211 (35%), Gaps = 30/211 (14%)

Query: 329  LSMGSPGPVTNKATKILRHFEASC---GQLSPARGTSAEPGPTAALPGPSDLLTDAVPLP 385
            LSM S  P   +AT   +   AS    G  +P   T   P    A P P    T     P
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP 970

Query: 386  ----GSQVFLQPLSS-TPVSSRSPAPSSG--------MPSSPVPTPP-----PDASPIPA 427
                G      P  + TP ++  P+P  G         P+ P  TPP     P A+P P 
Sbjct: 971  PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030

Query: 428  PGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGA 487
                  A    +      P+  P  T  PK  P++ A +  S   G    A P L GA  
Sbjct: 1031 GASTPPAATPPS------PKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGAPT 1081

Query: 488  AAGESCPDAPRAPQTSSQRTAAKEPPGSEPS 518
                + P     P T S + A   P  + PS
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 49/172 (28%), Positives = 64/172 (37%), Gaps = 34/172 (19%)

Query: 355  LSPARGTSAEPGPTAA-----LPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSG 409
            LSP +G +  P  T       LP P +    A P P     L   SS+P  +R+     G
Sbjct: 873  LSP-KGVTLPPKETPTPSVVNLPFPKE--GPATPAPKQAPALSMTSSSPKKARATPAPKG 929

Query: 410  MPSSPVP--TPPPDASPIPAP-GDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWS 466
            +P+SP P   P P A+  P+P G P+        S +W P        SPK GP      
Sbjct: 930  IPASPSPKGAPTPPAATPPSPKGGPA------TPSPKWAPTPPAATPPSPKGGP------ 977

Query: 467  RDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPS 518
                       A P   GA      + P     P T S + A   P  + PS
Sbjct: 978  -----------ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 50/181 (27%), Positives = 66/181 (36%), Gaps = 22/181 (12%)

Query: 353  GQLSPARGTSAEP-GPTAALPGPSDL-LTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
            G  +P   T   P G  AA P P     T A  LP  +       +TP    +P P +  
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG----PATPSLKGAPTPPAAT 1086

Query: 411  PSSPV---PTPPPDASPIPAPGDPSEAEARLA----ESRRWRPERIP----GG--TDSPK 457
            P SP     TP P  +P+P    P   +  LA    +     P   P    GG  T  PK
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146

Query: 458  RGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEP 517
              P++ A +  S   G+   A P   GA      + P       T S + A   P  + P
Sbjct: 1147 GAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203

Query: 518  S 518
            S
Sbjct: 1204 S 1204



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 49/175 (28%), Positives = 65/175 (37%), Gaps = 32/175 (18%)

Query: 369  AALPGPSDLLTDAVPLPGSQVFLQ--PLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIP 426
            AA P   DL   AV    + V L+  P +S P    +   S G P+ P  TPP    P P
Sbjct: 1425 AATPSKGDLTPPAV----TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP-P 1479

Query: 427  AP------GDPSEAEARLAE-SRRWRPERIPGGTDSPKRGPSSCAWSRDSL--------- 470
            AP        P +A A  A       P  IP    SPK  P++ +  RD +         
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIP---SSPKEVPATPSSRRDPIAPTATLLSK 1536

Query: 471  -----FAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAF 520
                  A  E +  P +         + P    AP T S + A+  PP   PS +
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS-SPPAVTPSTY 1590



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 46/177 (25%), Positives = 63/177 (35%), Gaps = 20/177 (11%)

Query: 355  LSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSP 414
            + PA    +  G  A  P      T A   P  +  L    +TP    +P   +  P SP
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL----ATPPPKGAPTTPAATPPSP 1159

Query: 415  ---VPTPPPDASPIPAPGDPSEAEARLA----ESRRWRPERIP----GG--TDSPKRGPS 461
               + TPPP  +P      P   +  LA    +     P   P    GG  T SPK  P+
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 462  SCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPS 518
            + A +  S   G+   A P   GA      + P     P T   + A   P  + PS
Sbjct: 1220 TPAATPPSPKGGL---ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPS 1273



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 39/130 (30%), Positives = 55/130 (42%), Gaps = 11/130 (8%)

Query: 332  GSPGPVTNKATKILRHFEASCGQLSPARGTSAEP-GPTAALPGPSDLLTDAVPLPGSQVF 390
            GS GP++  A   L   +    + +  +  S  P GP A  P  S   T        +V 
Sbjct: 1725 GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA--PPESKASTPLTAAAFEKVL 1782

Query: 391  LQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIP-APG----DPSEAEARLAESRRW- 444
             +P S++  ++ SP  S  +  SPVPT PP    +P +PG     PS+  A   E     
Sbjct: 1783 PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842

Query: 445  --RPERIPGG 452
               PE I GG
Sbjct: 1843 LIPPEPISGG 1852



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 28/110 (25%), Positives = 38/110 (34%), Gaps = 3/110 (2%)

Query: 356  SPARGTSAEPGPTAAL--PGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSS 413
            +P    +  P P   L  P P    T     P S        S   +  +PA +   P  
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253

Query: 414  PVPTPPPDASPIPAPGDPSEAEARLA-ESRRWRPERIPGGTDSPKRGPSS 462
               TPPP  +P P    P   +  LA    +  P        SPK GP++
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 17/111 (15%)

Query: 365  PGPTAALP-----GPSDLLTDAVPLPGSQVFLQPLSS--TPVSSRSPAPSSGMPSSPVPT 417
            P P    P     GP+       P P +     P  S  TP    +P P +  P SP  T
Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT 1346

Query: 418  PPPDASPIPAPGDPSEAEAR-------LAESRRWRPERIPGGTDSPKRGPS 461
            P   A+   + G P+   ++          S +  P   P    SPKRGP+
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP---PSPKRGPA 1394



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 45/188 (23%), Positives = 67/188 (35%), Gaps = 32/188 (17%)

Query: 359 RGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS---------- 408
           +G++    P   L  P   + +A  LP + +  Q    +P ++ SP P S          
Sbjct: 812 KGSAGPDTPIGNLSSPVSPV-EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870

Query: 409 ------GMPSSPVPTPPPDASPIPAPGD------PSEAEARLAES---RRWRPERIPGG- 452
                 G+   P  TP P    +P P +      P +A A    S   ++ R    P G 
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930

Query: 453 --TDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAK 510
             + SPK  P+  A +  S   G    A P    A      + P     P T S + A  
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGG---PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987

Query: 511 EPPGSEPS 518
            P  + PS
Sbjct: 988 PPAATPPS 995



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 36/153 (23%), Positives = 58/153 (37%), Gaps = 14/153 (9%)

Query: 367  PTAALPG---PSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDAS 423
            PTA L     P+ L      +P +     P  +  + +   AP++  PSS   + PP  +
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT--PSSKEASSPPAVT 1586

Query: 424  PIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLV 483
            P    G PS  E  +       P  +   + SPK  P+  A +  S   G    A     
Sbjct: 1587 PSTYKGAPSPKELLI-------PPAVT--SPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637

Query: 484  GAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSE 516
             +      S  D+P +P + + +  A  P  S+
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 25/87 (28%), Positives = 33/87 (37%), Gaps = 3/87 (3%)

Query: 353  GQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPA--PSSGM 410
            G  +P   T   P  T  LP  +         P S+    P ++TP     PA  P S  
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390

Query: 411  PSSPVPTPPPD-ASPIPAPGDPSEAEA 436
                +P+P  D  SP   P  P +A A
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPA 1417


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 60/238 (25%), Positives = 89/238 (37%), Gaps = 52/238 (21%)

Query: 297 QLRALCAIASLGSSDLL--PQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQ 354
           Q R+   +A +  ++ +  P E  L R+RP   + S  SP    + A             
Sbjct: 224 QSRSFRILAQMTGTEFMQDPDEEALRRSRP---QASSYSPAVAASSA------------- 267

Query: 355 LSPARGTSAEPGPTAALPGPSDLLTDAV--------------PLPGSQVFLQPLSSTPVS 400
             PA  TS   GP A  P P  + T ++              P PG+     P + +P  
Sbjct: 268 --PATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAP 325

Query: 401 SRSPAPSSGMPSSPVPTPPPDASPI----PAPG---DPSEAEARLAESRRWRPERIPGGT 453
           + +P+P+     SPVPT  P  +P     PAP     PS A +        RP  +   +
Sbjct: 326 AYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDS 385

Query: 454 DSPKRGP--SSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
            S K  P  S+ + S+ +L         PR   A   AG   P   R     ++R  A
Sbjct: 386 FSQKFAPGKSTTSISKQTL---------PRGGPAYTPAGPQVPPLARGTVQRAERFPA 434


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 54/185 (29%), Positives = 68/185 (36%), Gaps = 41/185 (22%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFL-----QPLSSTPVSSRSPAP---S 407
           SP    SA P P A  P  +  L  A P P +   L     Q L S P S    AP   S
Sbjct: 488 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547

Query: 408 SGMPSSPVPTPPPDASPIPA------PGDPSEAEARLAESRRWRP-------------ER 448
           + +P SP+ TPPP A P+ A      P  P  +    A  R   P               
Sbjct: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 607

Query: 449 IPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTA 508
            PG    P R PSS              ++ P L G  ++A  S P+  R   +  +  A
Sbjct: 608 APGPPPPPSRSPSS-------------TLSGPDLAGHSSSA-TSTPEELRGYDSGPEGGA 653

Query: 509 AKEPP 513
           A  PP
Sbjct: 654 AASPP 658



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 48/194 (24%), Positives = 71/194 (36%), Gaps = 28/194 (14%)

Query: 353 GQLSPARGT-SAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPA----PS 407
           G  SPA    S   G    LP P+       P  G +  +   S    +  SPA    PS
Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229

Query: 408 SG------------MPSSPVPTPP---PDASPIP-APGDPSEAEARLAESRRWRPERIPG 451
           +G              ++P+ +P    P A   P AP  PS+ + +  ++ R      P 
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 452 GTDSPKRGP-SSCAWSRDSLFAGMELVACPRLVGAGAAAGESC------PDAPRAPQTSS 504
              +P  GP SS   +  S  A ++  A P L     ++  +C      P AP +P    
Sbjct: 290 KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349

Query: 505 QRTAAKEPPGSEPS 518
                  PP + PS
Sbjct: 350 SLQTLPSPPATPPS 363



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 42/172 (24%), Positives = 66/172 (38%), Gaps = 26/172 (15%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           PGP+  K  +I         + + ARG + E    +AL   +   T   P PG+     P
Sbjct: 126 PGPLGQKGLRI-------SAEETVARGKATEAPKRSALSAGARRDTSG-PTPGT-----P 172

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGT 453
             +    SR+     G+P      P P A P P    P ++ +  +E     P      +
Sbjct: 173 SPAMARRSRAAGTEVGLPR-----PAPSARPRPPTEGPRKSVSSASEHSTTEP------S 221

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQ 505
            + +R PS+    +      +   A P  + + A +G S    PRAP   SQ
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATP--LSSPARSGPSARGTPRAPAHPSQ 271



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 87/357 (24%), Positives = 120/357 (33%), Gaps = 66/357 (18%)

Query: 138 PLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGW---DELDSG 194
           P  P  P   PP T         + L+  G +   GR  +  + G  GG         +G
Sbjct: 27  PRPPGSPRPPPPVTP--------AALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78

Query: 195 PS-SQNSSQNSDLSRVSDSG----SHSGSDSHSGASREPGDLAERVEVVALSDCQQELSL 249
           P+ S  +S  +  SR   SG    +    ++  G    PG  +       L      +S 
Sbjct: 79  PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138

Query: 250 VRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRALCAIA---- 305
             TV RG      +  A                 L     R TS  T      A+A    
Sbjct: 139 EETVARGKATEAPKRSA-----------------LSAGARRDTSGPTPGTPSPAMARRSR 181

Query: 306 SLGSSDLLPQEHILLRTRPWLQ----ELSMGSPGPVTNKATKILRHFEASCGQLSPAR-- 359
           + G+   LP+     R RP  +     +S  S    T  +    R   A  G   PA   
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241

Query: 360 -GTSAEPGPTAALPGPSDLLTDAVPLPGSQV------FLQPLSSTPVSSRSPAPSSG-MP 411
             +SA P  + A  GPS   T   P   SQ        L+P   TP   +  AP+ G + 
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PRKDAAPALGPLS 300

Query: 412 SSPVPTPPPDAS-------PIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPS 461
           SSP+ TP P A+        +PA    S    +LA         +P    SP   PS
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP-------LPLAPPSPSAPPS 350



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 29/162 (17%)

Query: 365 PGPTAALPGP--SDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS------GMPSSP-- 414
           PGP  ++ GP  +  L    P P S+     LS   ++  S + +S      G  S P  
Sbjct: 592 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651

Query: 415 --VPTPPPDASPI---PA-----PGDPSEAEARLAESRRWRPERIPGGTDS-----PKRG 459
               +PPPDA      PA     P  P            W P   PG  D         G
Sbjct: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711

Query: 460 PSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQ 501
           P S   +  +L  G      P   G  AAAG     + R+P+
Sbjct: 712 PESATPAPGALDPG----PSPGTSGGKAAAGAGAGASSRSPK 749



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 31/93 (33%), Positives = 35/93 (37%), Gaps = 9/93 (9%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLT---DAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPS 412
           SP     A P P A       LL       P P  Q    P +S PVS  +  PS   PS
Sbjct: 414 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473

Query: 413 SPVP----TPPPDASP--IPAPGDPSEAEARLA 439
              P     P P ASP   P+   P +A   LA
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 37/168 (22%), Positives = 59/168 (35%), Gaps = 14/168 (8%)

Query: 365 PGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPA--PSSGMPSSPVPTPPPDA 422
           P P A  P  +     +  L  +  FL     +P+++  P   P+  +P    P  PP +
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414

Query: 423 SPI-----PAPGDPSEAEARLAESRRWRPERIP-----GGTDSPKRGPSSCAWSRDSLFA 472
            P+     P+P  P+     L ++    P   P         SP   PS+   S+     
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474

Query: 473 GMELVACPRLVGAGAAAGESCPDAPRAPQ--TSSQRTAAKEPPGSEPS 518
               +  P    A      S    P+AP    +     AK PP + P+
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 35/164 (21%), Positives = 47/164 (28%), Gaps = 22/164 (13%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPV 415
           SP       P  T     P  L    + +P S     P+S +        P    P   +
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 416 PTPPPDASPIPA-------PGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRD 468
             PPP A P  A       P  P+    +   S        P  T  P+  P        
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-------- 564

Query: 469 SLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEP 512
                  ++A P L    +        APR P T    T+   P
Sbjct: 565 -------VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 601


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 54/185 (29%), Positives = 68/185 (36%), Gaps = 41/185 (22%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFL-----QPLSSTPVSSRSPAP---S 407
           SP    SA P P A  P  +  L  A P P +   L     Q L S P S    AP   S
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508

Query: 408 SGMPSSPVPTPPPDASPIPA------PGDPSEAEARLAESRRWRP-------------ER 448
           + +P SP+ TPPP A P+ A      P  P  +    A  R   P               
Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568

Query: 449 IPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTA 508
            PG    P R PSS              ++ P L G  ++A  S P+  R   +  +  A
Sbjct: 569 APGPPPPPSRSPSS-------------TLSGPDLAGHSSSA-TSTPEELRGYDSGPEGGA 614

Query: 509 AKEPP 513
           A  PP
Sbjct: 615 AASPP 619



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 77/317 (24%), Positives = 108/317 (34%), Gaps = 63/317 (19%)

Query: 138 PLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGW--------- 188
           P  P  P   PP T         + L+  G +   GR  +  + G  GG           
Sbjct: 27  PRPPGSPRPPPPVTP--------AALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78

Query: 189 DELDSGPSSQNSSQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELS 248
               S P +    + +  ++ +  G  S     SG +R PG L ++            +S
Sbjct: 79  PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR-PGPLGQK---------GLRIS 128

Query: 249 LVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRALCAIA--- 305
              TV RG      +  A                 L     R TS  T      A+A   
Sbjct: 129 AEETVARGKATEAPKRSA-----------------LSAGARRDTSGPTPGTPSPAMARRS 171

Query: 306 -SLGSSDLLPQEHILLRTRPWLQ----ELSMGSPGPVTNKATKILRHFEASCGQLSPAR- 359
            + G+   LP+     R RP  +     +S  S    T  +    R   A  G   PA  
Sbjct: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231

Query: 360 --GTSAEPGPTAALPGPSDLLTDAVPLPGSQV------FLQPLSSTPVSSRSPAPSSG-M 410
              +SA P  + A  GPS   T   P   SQ        L+P   TP   +  AP+ G +
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PRKDAAPALGPL 290

Query: 411 PSSPVPTPPPDASPIPA 427
            SSP+ TP P A P P+
Sbjct: 291 SSSPLATPSPSAPPSPS 307



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 42/172 (24%), Positives = 66/172 (38%), Gaps = 26/172 (15%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           PGP+  K  +I         + + ARG + E    +AL   +   T   P PG+     P
Sbjct: 117 PGPLGQKGLRI-------SAEETVARGKATEAPKRSALSAGARRDTSG-PTPGT-----P 163

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGT 453
             +    SR+     G+P      P P A P P    P ++ +  +E     P      +
Sbjct: 164 SPAMARRSRAAGTEVGLPR-----PAPSARPRPPTEGPRKSVSSASEHSTTEP------S 212

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQ 505
            + +R PS+    +      +   A P  + + A +G S    PRAP   SQ
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATP--LSSPARSGPSARGTPRAPAHPSQ 262



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 41/168 (24%), Positives = 55/168 (32%), Gaps = 6/168 (3%)

Query: 353 GQLSPARGT-SAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMP 411
           G  SPA    S   G    LP P+       P  G +  +   S    +  SPA +   P
Sbjct: 161 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRP 219

Query: 412 SSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLF 471
           S+      P +  + +   P  + AR   S R  P R P     PK  P      R    
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP-RAPAHPSQPK--PKGLQALRPPQV 276

Query: 472 AGMELVACPRLVGAGAAA-GESCPDAPRAPQTSSQRTAAKEPPGSEPS 518
                 A P L    ++      P AP +P           PP + PS
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 29/162 (17%)

Query: 365 PGPTAALPGP--SDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS------GMPSSP-- 414
           PGP  ++ GP  +  L    P P S+     LS   ++  S + +S      G  S P  
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612

Query: 415 --VPTPPPDASPI---PA-----PGDPSEAEARLAESRRWRPERIPGGTDS-----PKRG 459
               +PPPDA      PA     P  P            W P   PG  D         G
Sbjct: 613 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 672

Query: 460 PSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQ 501
           P S   +  +L  G      P   G  AAAG     + R+P+
Sbjct: 673 PESATPAPGALDPG----PSPGTSGGKAAAGAGAGASSRSPK 710



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 31/93 (33%), Positives = 35/93 (37%), Gaps = 9/93 (9%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLT---DAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPS 412
           SP     A P P A       LL       P P  Q    P +S PVS  +  PS   PS
Sbjct: 375 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434

Query: 413 SPVP----TPPPDASP--IPAPGDPSEAEARLA 439
              P     P P ASP   P+   P +A   LA
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 12/85 (14%)

Query: 356 SPARGTSAEPGPTAALPGP--SDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSS 413
           +PA  +  +P    AL  P  +    DA P  G      PLSS+P+++ SP+     P S
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALG------PLSSSPLATPSPS----APPS 305

Query: 414 PVPTPPPDASPIPAPGDPSEAEARL 438
           P   P     P P    PS+A   L
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSL 330



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 37/168 (22%), Positives = 59/168 (35%), Gaps = 14/168 (8%)

Query: 365 PGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPA--PSSGMPSSPVPTPPPDA 422
           P P A  P  +     +  L  +  FL     +P+++  P   P+  +P    P  PP +
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375

Query: 423 SPI-----PAPGDPSEAEARLAESRRWRPERIP-----GGTDSPKRGPSSCAWSRDSLFA 472
            P+     P+P  P+     L ++    P   P         SP   PS+   S+     
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435

Query: 473 GMELVACPRLVGAGAAAGESCPDAPRAPQ--TSSQRTAAKEPPGSEPS 518
               +  P    A      S    P+AP    +     AK PP + P+
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 483



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 35/164 (21%), Positives = 47/164 (28%), Gaps = 22/164 (13%)

Query: 356 SPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPV 415
           SP       P  T     P  L    + +P S     P+S +        P    P   +
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473

Query: 416 PTPPPDASPIPA-------PGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRD 468
             PPP A P  A       P  P+    +   S        P  T  P+  P        
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-------- 525

Query: 469 SLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEP 512
                  ++A P L    +        APR P T    T+   P
Sbjct: 526 -------VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 42/138 (30%), Positives = 61/138 (44%), Gaps = 27/138 (19%)

Query: 303  AIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTS 362
            A AS+   + LPQ+          Q+L +G   P+++         +A+  +LS  R   
Sbjct: 1470 ASASISQKNHLPQDS---------QDLVLGGDVPISS--------IQATIAKLS-IRPPG 1511

Query: 363  AEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAP-SSGMPSSPVPTPPPD 421
                P A+LPGP++        PG      P  STP+ S SP P SS +P +P P   P 
Sbjct: 1512 GLESPVASLPGPAEP-------PGLPPASLP-ESTPIPSSSPPPLSSPLPEAPQPKEEPP 1563

Query: 422  ASPIPAPGDPSEAEARLA 439
                P+ G PS +   LA
Sbjct: 1564 VPEAPSSGPPSSSLELLA 1581



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 44/131 (33%), Positives = 48/131 (36%), Gaps = 25/131 (19%)

Query: 353  GQLSPARGTSAEPGPTA-ALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSP------- 404
            GQ  P   T   PGP    LP  S  L    P P  Q    PL+  P  S  P       
Sbjct: 1008 GQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGP-PQPPHPPLAYGPAPSTRPMGPQAAP 1066

Query: 405  ----APSSGMPSSP----VPTPPPDASPIPAPGDPSEAE--------ARLAESRRWRPER 448
                 PSS   S+P    VP+P P   P P P  P  AE        A  A+     PE 
Sbjct: 1067 LTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPES 1126

Query: 449  IPGGTDSPKRG 459
              GGT SP  G
Sbjct: 1127 QHGGTQSPGGG 1137



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 28/111 (25%), Positives = 40/111 (36%), Gaps = 12/111 (10%)

Query: 353 GQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPS 412
           G   P  G  + P P  + P  +  +  A     S     P+ S      +P P+   P 
Sbjct: 852 GPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDS--IQAPIPSHTAPRPNPTPAPPPPC 909

Query: 413 SPVPTPPPDASPIPAPG---DPSEAEARLAESRRWRPERIPGGTDSPKRGP 460
            PVP P P  +P   P     P  A+   +         IP G  +P+ GP
Sbjct: 910 FPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSG-------IPAGFPAPRIGP 953



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 9/77 (11%)

Query: 361 TSAEPGPTAALPGPSDLLTDAVPLPGSQVF----LQPLS-----STPVSSRSPAPSSGMP 411
           T+  P PT A P P   +    PLP    +     QP+      S+ + +  PAP  G  
Sbjct: 895 TAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQ 954

Query: 412 SSPVPTPPPDASPIPAP 428
             P P P P  +  P P
Sbjct: 955 PQPHPQPHPSQAFGPQP 971


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 35/101 (34%), Positives = 40/101 (39%), Gaps = 19/101 (18%)

Query: 353 GQLSPARGTSAEPGPTAALPGPSDLL-------------TDAVPLPGSQVFLQPLSSTPV 399
           G  SP    +AEP P AA P P  L                A PLPGS    +P  + P+
Sbjct: 524 GSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSP---EPPPAPPL 580

Query: 400 SSRSPAPSSGMPSSPV---PTPPPDASPIPAPGDPSEAEAR 437
               P P    P  P    P PPP   P P PG P +A  R
Sbjct: 581 PGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGR 621



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 39/135 (28%), Positives = 51/135 (37%), Gaps = 24/135 (17%)

Query: 348 FEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPL-----------PGSQVFLQPLS- 395
           F  S    +  R    E  P AA   PS L      L           PG  V ++ L  
Sbjct: 447 FSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPV 506

Query: 396 --STPVSSRSPAPS--SGMPS---SPVPTPPPDAS---PIPAPGDPSEAEARLAESRRWR 445
             +TP    +P P   +G PS   +P   P P A+   P P PG PS  EA  +   +  
Sbjct: 507 AVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAP 566

Query: 446 PERIPGGTDSPKRGP 460
           P  +PG  + P   P
Sbjct: 567 P--LPGSPEPPPAPP 579


>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
           epsilon, 47kDa [Homo sapiens]
          Length = 357

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 20/66 (30%), Positives = 34/66 (51%)

Query: 396 STPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDS 455
           S P ++ +P P++   S P PTP P A+P+PA    S ++   A +    P + P    +
Sbjct: 9   SAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQA 68

Query: 456 PKRGPS 461
           P + P+
Sbjct: 69  PAQTPA 74



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 3/73 (4%)

Query: 357 PARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVP 416
           PA   ++ P PT   P P+     A     S       ++T    ++PA +     +P P
Sbjct: 19  PAAAPASVPAPT---PAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAP 75

Query: 417 TPPPDASPIPAPG 429
             P  A P P PG
Sbjct: 76  ALPGPALPGPFPG 88



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 27/108 (25%), Positives = 36/108 (33%), Gaps = 25/108 (23%)

Query: 411 PSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSL 470
           P+ PV  PP   +P+PA                  P  +P  T +P   P   A    S 
Sbjct: 4   PAVPVSAPPATPTPVPAAA----------------PASVPAPTPAPAAAPVPAAAPASS- 46

Query: 471 FAGMELVACPRLVGAGAAAGESCPDAPRAP-QTSSQRTAAKEPPGSEP 517
                  + P    A  AA    P + +AP QT +        PG  P
Sbjct: 47  -------SDPAAAAAATAAPGQTPASAQAPAQTPAPALPGPALPGPFP 87


>gi|116256475 zinc finger protein 827 [Homo sapiens]
          Length = 1077

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 73/330 (22%), Positives = 116/330 (35%), Gaps = 23/330 (6%)

Query: 143 QPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGWDELDSGPSSQNSSQ 202
           Q   T P T +GS      TL+      E  R +++ Q   + G     D  P S N   
Sbjct: 61  QEQSTSPDTSLGSTTPSSHTLELVALDSEVLRDSLQCQDHLSPGVSSLCDDDPGS-NKPL 119

Query: 203 NSDLSRVSDSGSHS--GSDSHSGASREPGDLAERVEVVALSDCQQELS-LVRTVTRGPRA 259
           +S+L R+ ++GS     + + +G    P ++   +     S   Q+LS L R +      
Sbjct: 120 SSNLRRLLEAGSLKLDAAATANGRVESPVNVGSNLSFSPPSHHAQQLSVLARKLAEKQEQ 179

Query: 260 FLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRALCAIASLGSSDLLPQEHIL 319
                 +  FI   G     +     TC L   S   +L+A        +++ + Q+  L
Sbjct: 180 NDQYTPSNRFIWNQGKWLPNSTT---TCSLSPDSAILKLKA--------AANAVLQDKSL 228

Query: 320 LRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPT-----AALPGP 374
            RT   ++  S  SP   +  A+  L        + S   G    P  +     A++   
Sbjct: 229 TRTEETMRFESFSSPFS-SQSASSTLAALSKKVSERSLTPGQEHPPPASSFLSLASMTSS 287

Query: 375 SDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEA 434
           + LL +        +  +  S  P     P PS   P    P PPP   P P P  P   
Sbjct: 288 AALLKEVAARAAGSLLAEKSSLLPEDPLPPPPSEKKPEKVTPPPPPPPPP-PPPPPPQSL 346

Query: 435 EARLAESRRWRPERIPGGTDSPKRG-PSSC 463
           E  L    + R  +        + G P  C
Sbjct: 347 ELLLLPVPKGRVSKPSNSASEEESGKPFQC 376


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 5/103 (4%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K+        A      PA  T  EP PT            A   P       P
Sbjct: 247 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI---PAPGDPSE 433
               P + + PAP++  P  P PT P + +P    PAP  P E
Sbjct: 307 KKPAPTTPKEPAPTT--PKEPTPTTPKEPAPTTKEPAPTTPKE 347



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/170 (24%), Positives = 60/170 (35%), Gaps = 16/170 (9%)

Query: 357 PARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVP 416
           P   T  EP PT   P P+   T   P P +     P    P + + PAP++  P  P P
Sbjct: 325 PTPTTPKEPAPTTKEPAPT---TPKEPAPTA-----PKKPAPTTPKEPAPTT--PKEPAP 374

Query: 417 TPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGME 475
           T   + SP  P    P+  ++    ++   P        +PK  PS       +     E
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKE 433

Query: 476 LVACPRLVGAGAAAGESCPDAPRAPQTSSQR----TAAKEPPGSEPSAFA 521
                    A     E  P  P+ P  ++ +    T  KEP  + P   A
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 16/190 (8%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K+        +      PA  T  EP PT    P P+   T   P P +     
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTT----- 454

Query: 393 PLSSTPVSSRSPAPSSGMPSSPVPTPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPG 451
           P    P +++ PAP++  P  P PT P + +P  P    P+  E +LA +   +P     
Sbjct: 455 PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTP 511

Query: 452 GTDSPKRGPSSCAWSRDSLFAGMELVACPRL--VGAGAAAGESCPDAPRAP-QTSSQRTA 508
              +P         + +         A P      A     E  P  P+ P  T+ + TA
Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571

Query: 509 AKEPPGSEPS 518
              P G+ P+
Sbjct: 572 PTTPKGTAPT 581



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 41/140 (29%), Positives = 54/140 (38%), Gaps = 24/140 (17%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T       A       A  T  EP PT    P P +L       P S    +
Sbjct: 562 PAPTTPKET-------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSE-AEARLAESR 442
           P  +T     P + + PAP++  P  P PT P   +P     PAP  P + A   LA + 
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT- 671

Query: 443 RWRPERIPGGTDSPKRGPSS 462
                + P  T S K  P++
Sbjct: 672 ---TTKGPTSTTSDKPAPTT 688



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 31/112 (27%), Positives = 38/112 (33%), Gaps = 14/112 (12%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL--------PGPSDLLTDAVPLP 385
           P P T K        E +      A  T+ EP PT           P P+     A   P
Sbjct: 372 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431

Query: 386 GSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPT----PPPDASPIPAPGDPSE 433
                  P    P + + PAP++  P  P PT    P P     PAP  P E
Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTT--PKEPAPTTTKKPAPTTPKEPAPTTPKE 481



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 53/238 (22%), Positives = 75/238 (31%), Gaps = 60/238 (25%)

Query: 291 GTSECTQLRALCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEA 350
           G  + T  +   +I    + DL P   +L +            P P     TK       
Sbjct: 166 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAK------------PTPKAETTTK------- 206

Query: 351 SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS-- 408
                 PA  T  EP PT   P      T   P P +      + S P + + PAP++  
Sbjct: 207 -----GPALTTPKEPTPTT--PKEPASTTPKEPTPTT------IKSAPTTPKEPAPTTTK 253

Query: 409 ---GMPSSPVPT----PPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPS 461
                P  P PT    P P     PAP    E      +S    P+  P  T   K  P+
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPT 312

Query: 462 SCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSA 519
           +                 P+   A     E  P  P+ P  +++  A   P    P+A
Sbjct: 313 T-----------------PK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 352



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 27/110 (24%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T               A  T  EP PT    P P +L       P S    +
Sbjct: 639 PAPTTPKGT---------------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 683

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVP----TPPPDASPIPAPGDPSE 433
           P  +T     P + + PAP++  P  P P    TPPP  S +  P    E
Sbjct: 684 PAPTTPKETAPTTPKEPAPTT--PKKPAPTTPETPPPTTSEVSTPTTTKE 731



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 46/195 (23%), Positives = 62/195 (31%), Gaps = 34/195 (17%)

Query: 357 PARGTSAEPGPTA---ALPGPSDLLTDAVP--------------LPGSQVFLQPLSSTPV 399
           PA  T  EP PT      P     LT   P               P       P   TP 
Sbjct: 466 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 525

Query: 400 SSRSPAPSS------GMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
           +   PAP++        P  P PT P + +P     PAP  P E      +       + 
Sbjct: 526 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585

Query: 450 PGGTDSPKRGPSSCA--WSRDSLFAGMELVACPRLVG-AGAAAGESCPDAPRAPQTSSQR 506
           P  T   K  P   A   +++      +  A     G A     E  P  P+ P  ++ +
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645

Query: 507 ----TAAKEPPGSEP 517
               T  KEP  + P
Sbjct: 646 GTAPTTLKEPAPTTP 660



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 44/182 (24%), Positives = 62/182 (34%), Gaps = 24/182 (13%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K T       A      PA  T  EP PT   P  +   T   P P +     P
Sbjct: 615 PAPTTPKGT-------APTTPKEPAPTTPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAP 665

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
               P +++   P+S     P PT P + +P     PAP  P +      E+    P   
Sbjct: 666 KELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTS 721

Query: 450 PGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
              T +  + P++   S D     +     P+       A E+ P  P  P T +     
Sbjct: 722 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-------ALENSPKEPGVPTTKTPAATK 774

Query: 510 KE 511
            E
Sbjct: 775 PE 776



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 41/184 (22%), Positives = 59/184 (32%), Gaps = 29/184 (15%)

Query: 358 ARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM------ 410
           A  T  EP PT    P P+     A   P       P  + P + + PAP++        
Sbjct: 539 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 598

Query: 411 --------PSS-----PVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERIPGGT 453
                   P+S     P PT P   +P     PAP  P E      +       + P  T
Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPP 513
              K  P   A    +   G       +   A     E+ P  P+ P  ++ +  A   P
Sbjct: 659 TPKKPAPKELA---PTTTKGPTSTTSDK--PAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713

Query: 514 GSEP 517
            + P
Sbjct: 714 ETPP 717


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 5/103 (4%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K+        A      PA  T  EP PT            A   P       P
Sbjct: 288 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI---PAPGDPSE 433
               P + + PAP++  P  P PT P + +P    PAP  P E
Sbjct: 348 KKPAPTTPKEPAPTT--PKEPTPTTPKEPAPTTKEPAPTTPKE 388



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/170 (24%), Positives = 60/170 (35%), Gaps = 16/170 (9%)

Query: 357 PARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVP 416
           P   T  EP PT   P P+   T   P P +     P    P + + PAP++  P  P P
Sbjct: 366 PTPTTPKEPAPTTKEPAPT---TPKEPAPTA-----PKKPAPTTPKEPAPTT--PKEPAP 415

Query: 417 TPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGME 475
           T   + SP  P    P+  ++    ++   P        +PK  PS       +     E
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKE 474

Query: 476 LVACPRLVGAGAAAGESCPDAPRAPQTSSQR----TAAKEPPGSEPSAFA 521
                    A     E  P  P+ P  ++ +    T  KEP  + P   A
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 16/190 (8%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K+        +      PA  T  EP PT    P P+   T   P P +     
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTT----- 495

Query: 393 PLSSTPVSSRSPAPSSGMPSSPVPTPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPG 451
           P    P +++ PAP++  P  P PT P + +P  P    P+  E +LA +   +P     
Sbjct: 496 PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTP 552

Query: 452 GTDSPKRGPSSCAWSRDSLFAGMELVACPRL--VGAGAAAGESCPDAPRAP-QTSSQRTA 508
              +P         + +         A P      A     E  P  P+ P  T+ + TA
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612

Query: 509 AKEPPGSEPS 518
              P G+ P+
Sbjct: 613 PTTPKGTAPT 622



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 41/140 (29%), Positives = 54/140 (38%), Gaps = 24/140 (17%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T       A       A  T  EP PT    P P +L       P S    +
Sbjct: 603 PAPTTPKET-------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSE-AEARLAESR 442
           P  +T     P + + PAP++  P  P PT P   +P     PAP  P + A   LA + 
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT- 712

Query: 443 RWRPERIPGGTDSPKRGPSS 462
                + P  T S K  P++
Sbjct: 713 ---TTKGPTSTTSDKPAPTT 729



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 31/112 (27%), Positives = 38/112 (33%), Gaps = 14/112 (12%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL--------PGPSDLLTDAVPLP 385
           P P T K        E +      A  T+ EP PT           P P+     A   P
Sbjct: 413 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472

Query: 386 GSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPT----PPPDASPIPAPGDPSE 433
                  P    P + + PAP++  P  P PT    P P     PAP  P E
Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTT--PKEPAPTTTKKPAPTTPKEPAPTTPKE 522



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 53/238 (22%), Positives = 75/238 (31%), Gaps = 60/238 (25%)

Query: 291 GTSECTQLRALCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEA 350
           G  + T  +   +I    + DL P   +L +            P P     TK       
Sbjct: 207 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAK------------PTPKAETTTK------- 247

Query: 351 SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS-- 408
                 PA  T  EP PT   P      T   P P +      + S P + + PAP++  
Sbjct: 248 -----GPALTTPKEPTPTT--PKEPASTTPKEPTPTT------IKSAPTTPKEPAPTTTK 294

Query: 409 ---GMPSSPVPT----PPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPS 461
                P  P PT    P P     PAP    E      +S    P+  P  T   K  P+
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPT 353

Query: 462 SCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSA 519
           +                 P+   A     E  P  P+ P  +++  A   P    P+A
Sbjct: 354 T-----------------PK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 393



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 27/110 (24%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T               A  T  EP PT    P P +L       P S    +
Sbjct: 680 PAPTTPKGT---------------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 724

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVP----TPPPDASPIPAPGDPSE 433
           P  +T     P + + PAP++  P  P P    TPPP  S +  P    E
Sbjct: 725 PAPTTPKETAPTTPKEPAPTT--PKKPAPTTPETPPPTTSEVSTPTTTKE 772



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 46/195 (23%), Positives = 62/195 (31%), Gaps = 34/195 (17%)

Query: 357 PARGTSAEPGPTA---ALPGPSDLLTDAVP--------------LPGSQVFLQPLSSTPV 399
           PA  T  EP PT      P     LT   P               P       P   TP 
Sbjct: 507 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 566

Query: 400 SSRSPAPSS------GMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
           +   PAP++        P  P PT P + +P     PAP  P E      +       + 
Sbjct: 567 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626

Query: 450 PGGTDSPKRGPSSCA--WSRDSLFAGMELVACPRLVG-AGAAAGESCPDAPRAPQTSSQR 506
           P  T   K  P   A   +++      +  A     G A     E  P  P+ P  ++ +
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686

Query: 507 ----TAAKEPPGSEP 517
               T  KEP  + P
Sbjct: 687 GTAPTTLKEPAPTTP 701



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 44/182 (24%), Positives = 62/182 (34%), Gaps = 24/182 (13%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K T       A      PA  T  EP PT   P  +   T   P P +     P
Sbjct: 656 PAPTTPKGT-------APTTPKEPAPTTPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAP 706

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
               P +++   P+S     P PT P + +P     PAP  P +      E+    P   
Sbjct: 707 KELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTS 762

Query: 450 PGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
              T +  + P++   S D     +     P+       A E+ P  P  P T +     
Sbjct: 763 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-------ALENSPKEPGVPTTKTPAATK 815

Query: 510 KE 511
            E
Sbjct: 816 PE 817



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 41/184 (22%), Positives = 59/184 (32%), Gaps = 29/184 (15%)

Query: 358 ARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM------ 410
           A  T  EP PT    P P+     A   P       P  + P + + PAP++        
Sbjct: 580 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 639

Query: 411 --------PSS-----PVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERIPGGT 453
                   P+S     P PT P   +P     PAP  P E      +       + P  T
Sbjct: 640 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 699

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPP 513
              K  P   A    +   G       +   A     E+ P  P+ P  ++ +  A   P
Sbjct: 700 TPKKPAPKELA---PTTTKGPTSTTSDK--PAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754

Query: 514 GSEP 517
            + P
Sbjct: 755 ETPP 758


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 5/103 (4%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K+        A      PA  T  EP PT            A   P       P
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI---PAPGDPSE 433
               P + + PAP++  P  P PT P + +P    PAP  P E
Sbjct: 400 KKPAPTTPKEPAPTT--PKEPTPTTPKEPAPTTKEPAPTTPKE 440



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/170 (24%), Positives = 60/170 (35%), Gaps = 16/170 (9%)

Query: 357 PARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVP 416
           P   T  EP PT   P P+   T   P P +     P    P + + PAP++  P  P P
Sbjct: 418 PTPTTPKEPAPTTKEPAPT---TPKEPAPTA-----PKKPAPTTPKEPAPTT--PKEPAP 467

Query: 417 TPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGME 475
           T   + SP  P    P+  ++    ++   P        +PK  PS       +     E
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKE 526

Query: 476 LVACPRLVGAGAAAGESCPDAPRAPQTSSQR----TAAKEPPGSEPSAFA 521
                    A     E  P  P+ P  ++ +    T  KEP  + P   A
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 16/190 (8%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K+        +      PA  T  EP PT    P P+   T   P P +     
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTT----- 547

Query: 393 PLSSTPVSSRSPAPSSGMPSSPVPTPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPG 451
           P    P +++ PAP++  P  P PT P + +P  P    P+  E +LA +   +P     
Sbjct: 548 PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTP 604

Query: 452 GTDSPKRGPSSCAWSRDSLFAGMELVACPRL--VGAGAAAGESCPDAPRAP-QTSSQRTA 508
              +P         + +         A P      A     E  P  P+ P  T+ + TA
Sbjct: 605 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 664

Query: 509 AKEPPGSEPS 518
              P G+ P+
Sbjct: 665 PTTPKGTAPT 674



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 41/140 (29%), Positives = 54/140 (38%), Gaps = 24/140 (17%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T       A       A  T  EP PT    P P +L       P S    +
Sbjct: 655 PAPTTPKET-------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSE-AEARLAESR 442
           P  +T     P + + PAP++  P  P PT P   +P     PAP  P + A   LA + 
Sbjct: 708 PAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT- 764

Query: 443 RWRPERIPGGTDSPKRGPSS 462
                + P  T S K  P++
Sbjct: 765 ---TTKGPTSTTSDKPAPTT 781



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 31/112 (27%), Positives = 38/112 (33%), Gaps = 14/112 (12%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL--------PGPSDLLTDAVPLP 385
           P P T K        E +      A  T+ EP PT           P P+     A   P
Sbjct: 465 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524

Query: 386 GSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPT----PPPDASPIPAPGDPSE 433
                  P    P + + PAP++  P  P PT    P P     PAP  P E
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTT--PKEPAPTTTKKPAPTTPKEPAPTTPKE 574



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 53/238 (22%), Positives = 75/238 (31%), Gaps = 60/238 (25%)

Query: 291 GTSECTQLRALCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEA 350
           G  + T  +   +I    + DL P   +L +            P P     TK       
Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAK------------PTPKAETTTK------- 299

Query: 351 SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS-- 408
                 PA  T  EP PT   P      T   P P +      + S P + + PAP++  
Sbjct: 300 -----GPALTTPKEPTPTT--PKEPASTTPKEPTPTT------IKSAPTTPKEPAPTTTK 346

Query: 409 ---GMPSSPVPT----PPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPS 461
                P  P PT    P P     PAP    E      +S    P+  P  T   K  P+
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPT 405

Query: 462 SCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSA 519
           +                 P+   A     E  P  P+ P  +++  A   P    P+A
Sbjct: 406 T-----------------PK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 445



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 27/110 (24%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T               A  T  EP PT    P P +L       P S    +
Sbjct: 732 PAPTTPKGT---------------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 776

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVP----TPPPDASPIPAPGDPSE 433
           P  +T     P + + PAP++  P  P P    TPPP  S +  P    E
Sbjct: 777 PAPTTPKETAPTTPKEPAPTT--PKKPAPTTPETPPPTTSEVSTPTTTKE 824



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 46/195 (23%), Positives = 62/195 (31%), Gaps = 34/195 (17%)

Query: 357 PARGTSAEPGPTA---ALPGPSDLLTDAVP--------------LPGSQVFLQPLSSTPV 399
           PA  T  EP PT      P     LT   P               P       P   TP 
Sbjct: 559 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 618

Query: 400 SSRSPAPSS------GMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
           +   PAP++        P  P PT P + +P     PAP  P E      +       + 
Sbjct: 619 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 678

Query: 450 PGGTDSPKRGPSSCA--WSRDSLFAGMELVACPRLVG-AGAAAGESCPDAPRAPQTSSQR 506
           P  T   K  P   A   +++      +  A     G A     E  P  P+ P  ++ +
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738

Query: 507 ----TAAKEPPGSEP 517
               T  KEP  + P
Sbjct: 739 GTAPTTLKEPAPTTP 753



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 44/182 (24%), Positives = 62/182 (34%), Gaps = 24/182 (13%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K T       A      PA  T  EP PT   P  +   T   P P +     P
Sbjct: 708 PAPTTPKGT-------APTTPKEPAPTTPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAP 758

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
               P +++   P+S     P PT P + +P     PAP  P +      E+    P   
Sbjct: 759 KELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTS 814

Query: 450 PGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
              T +  + P++   S D     +     P+       A E+ P  P  P T +     
Sbjct: 815 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-------ALENSPKEPGVPTTKTPAATK 867

Query: 510 KE 511
            E
Sbjct: 868 PE 869



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 41/184 (22%), Positives = 59/184 (32%), Gaps = 29/184 (15%)

Query: 358 ARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM------ 410
           A  T  EP PT    P P+     A   P       P  + P + + PAP++        
Sbjct: 632 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 691

Query: 411 --------PSS-----PVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERIPGGT 453
                   P+S     P PT P   +P     PAP  P E      +       + P  T
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 751

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPP 513
              K  P   A    +   G       +   A     E+ P  P+ P  ++ +  A   P
Sbjct: 752 TPKKPAPKELA---PTTTKGPTSTTSDK--PAPTTPKETAPTTPKEPAPTTPKKPAPTTP 806

Query: 514 GSEP 517
            + P
Sbjct: 807 ETPP 810


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/103 (29%), Positives = 37/103 (35%), Gaps = 5/103 (4%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K+        A      PA  T  EP PT            A   P       P
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI---PAPGDPSE 433
               P + + PAP++  P  P PT P + +P    PAP  P E
Sbjct: 441 KKPAPTTPKEPAPTT--PKEPTPTTPKEPAPTTKEPAPTTPKE 481



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/170 (24%), Positives = 60/170 (35%), Gaps = 16/170 (9%)

Query: 357 PARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVP 416
           P   T  EP PT   P P+   T   P P +     P    P + + PAP++  P  P P
Sbjct: 459 PTPTTPKEPAPTTKEPAPT---TPKEPAPTA-----PKKPAPTTPKEPAPTT--PKEPAP 508

Query: 417 TPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGME 475
           T   + SP  P    P+  ++    ++   P        +PK  PS       +     E
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKE 567

Query: 476 LVACPRLVGAGAAAGESCPDAPRAPQTSSQR----TAAKEPPGSEPSAFA 521
                    A     E  P  P+ P  ++ +    T  KEP  + P   A
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 16/190 (8%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K+        +      PA  T  EP PT    P P+   T   P P +     
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT---TPKEPAPTT----- 588

Query: 393 PLSSTPVSSRSPAPSSGMPSSPVPTPPPDASP-IPAPGDPSEAEARLAESRRWRPERIPG 451
           P    P +++ PAP++  P  P PT P + +P  P    P+  E +LA +   +P     
Sbjct: 589 PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTP 645

Query: 452 GTDSPKRGPSSCAWSRDSLFAGMELVACPRL--VGAGAAAGESCPDAPRAP-QTSSQRTA 508
              +P         + +         A P      A     E  P  P+ P  T+ + TA
Sbjct: 646 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 705

Query: 509 AKEPPGSEPS 518
              P G+ P+
Sbjct: 706 PTTPKGTAPT 715



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 41/140 (29%), Positives = 54/140 (38%), Gaps = 24/140 (17%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T       A       A  T  EP PT    P P +L       P S    +
Sbjct: 696 PAPTTPKET-------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSE-AEARLAESR 442
           P  +T     P + + PAP++  P  P PT P   +P     PAP  P + A   LA + 
Sbjct: 749 PAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT- 805

Query: 443 RWRPERIPGGTDSPKRGPSS 462
                + P  T S K  P++
Sbjct: 806 ---TTKGPTSTTSDKPAPTT 822



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 31/112 (27%), Positives = 38/112 (33%), Gaps = 14/112 (12%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL--------PGPSDLLTDAVPLP 385
           P P T K        E +      A  T+ EP PT           P P+     A   P
Sbjct: 506 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565

Query: 386 GSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPT----PPPDASPIPAPGDPSE 433
                  P    P + + PAP++  P  P PT    P P     PAP  P E
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTT--PKEPAPTTTKKPAPTTPKEPAPTTPKE 615



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 53/238 (22%), Positives = 75/238 (31%), Gaps = 60/238 (25%)

Query: 291 GTSECTQLRALCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEA 350
           G  + T  +   +I    + DL P   +L +            P P     TK       
Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAK------------PTPKAETTTK------- 340

Query: 351 SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSS-- 408
                 PA  T  EP PT   P      T   P P +      + S P + + PAP++  
Sbjct: 341 -----GPALTTPKEPTPTT--PKEPASTTPKEPTPTT------IKSAPTTPKEPAPTTTK 387

Query: 409 ---GMPSSPVPT----PPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPS 461
                P  P PT    P P     PAP    E      +S    P+  P  T   K  P+
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPT 446

Query: 462 SCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSA 519
           +                 P+   A     E  P  P+ P  +++  A   P    P+A
Sbjct: 447 T-----------------PK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 486



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 27/110 (24%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQ 392
           P P T K T               A  T  EP PT    P P +L       P S    +
Sbjct: 773 PAPTTPKGT---------------APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 817

Query: 393 PLSST-----PVSSRSPAPSSGMPSSPVP----TPPPDASPIPAPGDPSE 433
           P  +T     P + + PAP++  P  P P    TPPP  S +  P    E
Sbjct: 818 PAPTTPKETAPTTPKEPAPTT--PKKPAPTTPETPPPTTSEVSTPTTTKE 865



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 46/195 (23%), Positives = 62/195 (31%), Gaps = 34/195 (17%)

Query: 357 PARGTSAEPGPTA---ALPGPSDLLTDAVP--------------LPGSQVFLQPLSSTPV 399
           PA  T  EP PT      P     LT   P               P       P   TP 
Sbjct: 600 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 659

Query: 400 SSRSPAPSS------GMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
           +   PAP++        P  P PT P + +P     PAP  P E      +       + 
Sbjct: 660 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719

Query: 450 PGGTDSPKRGPSSCA--WSRDSLFAGMELVACPRLVG-AGAAAGESCPDAPRAPQTSSQR 506
           P  T   K  P   A   +++      +  A     G A     E  P  P+ P  ++ +
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779

Query: 507 ----TAAKEPPGSEP 517
               T  KEP  + P
Sbjct: 780 GTAPTTLKEPAPTTP 794



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 44/182 (24%), Positives = 62/182 (34%), Gaps = 24/182 (13%)

Query: 334 PGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQP 393
           P P T K T       A      PA  T  EP PT   P  +   T   P P +     P
Sbjct: 749 PAPTTPKGT-------APTTPKEPAPTTPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAP 799

Query: 394 LSSTPVSSRSPAPSSGMPSSPVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERI 449
               P +++   P+S     P PT P + +P     PAP  P +      E+    P   
Sbjct: 800 KELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTS 855

Query: 450 PGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAA 509
              T +  + P++   S D     +     P+       A E+ P  P  P T +     
Sbjct: 856 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-------ALENSPKEPGVPTTKTPAATK 908

Query: 510 KE 511
            E
Sbjct: 909 PE 910



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 41/184 (22%), Positives = 59/184 (32%), Gaps = 29/184 (15%)

Query: 358 ARGTSAEPGPTAAL-PGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM------ 410
           A  T  EP PT    P P+     A   P       P  + P + + PAP++        
Sbjct: 673 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 732

Query: 411 --------PSS-----PVPTPPPDASPI----PAPGDPSEAEARLAESRRWRPERIPGGT 453
                   P+S     P PT P   +P     PAP  P E      +       + P  T
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792

Query: 454 DSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPP 513
              K  P   A    +   G       +   A     E+ P  P+ P  ++ +  A   P
Sbjct: 793 TPKKPAPKELA---PTTTKGPTSTTSDK--PAPTTPKETAPTTPKEPAPTTPKKPAPTTP 847

Query: 514 GSEP 517
            + P
Sbjct: 848 ETPP 851


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 42/171 (24%), Positives = 65/171 (38%), Gaps = 9/171 (5%)

Query: 356  SPARG--TSAEP-GPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPS 412
            SPA    T  EP  P AA+P P +  + A  +P  +    P ++ P      +P++ +P+
Sbjct: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061

Query: 413  SPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFA 472
               PT P  A  +P P +P+   A +              T      P++   + +   +
Sbjct: 1062 PEEPTSPAAA--VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS 1119

Query: 473  GMELVACPRLVGAGAAA----GESCPDAPRAPQTSSQRTAAKEPPGSEPSA 519
                V  P    + AAA     E    AP  P      +AA   P  E SA
Sbjct: 1120 PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 51/177 (28%), Positives = 70/177 (39%), Gaps = 35/177 (19%)

Query: 356  SPARG--TSAEPG-PTAALPGPSDLLTD--AVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
            SPA    T  EP  P AA+P P +  +   AVP P    F  P   TP  S S A +   
Sbjct: 1106 SPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA--- 1162

Query: 411  PSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSL 470
                VPTP   ASP  A   P+E+ +  A         +    + P   P++   +  ++
Sbjct: 1163 ----VPTPEESASPAAAVPTPAESASFAA---------VVATLEEP-TSPAASVPTPAAM 1208

Query: 471  FAGMELVACPRL------VGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFA 521
             A +E    P          A  AA  S P+ P +P       AA  P   EP++ A
Sbjct: 1209 VATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP-------AAAVPTLEEPTSSA 1258



 Score = 32.7 bits (73), Expect = 0.83
 Identities = 32/153 (20%), Positives = 58/153 (37%), Gaps = 10/153 (6%)

Query: 367  PTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIP 426
            P   +  P +  T AV +   +    P ++ P      +P++ +P+   PT P  A  +P
Sbjct: 977  PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA--VP 1034

Query: 427  APGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAG 486
             P +P+   A +              T      P++   + +   +    V  P    + 
Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094

Query: 487  AAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSA 519
            AAA  + P+ P +P       AA  P   EP++
Sbjct: 1095 AAAVPT-PEEPTSP-------AAAVPTPEEPAS 1119



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 14/58 (24%), Positives = 27/58 (46%)

Query: 367  PTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASP 424
            P A++P P +  + A  +   +    P ++ P    +  P++ +P+  VP  P  A P
Sbjct: 1270 PAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVP 1327



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 17/112 (15%)

Query: 338  TNKATKILRHFEASCGQLSPARG--TSAEPG-PTAALPGPSDLLTDAVPLPGSQVFLQPL 394
            T+ A  +L   E S    SPA    T  EP  P AA+    +  + A  +P  +V   P 
Sbjct: 1255 TSSAAAVLTPEELS----SPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA 1310

Query: 395  SSTPVSSRSPAPSSGMPS----SPVPTP------PPDASPIPAPGDPSEAEA 436
            +S P       P++ +P     SP+  P        D+ PI   G P   EA
Sbjct: 1311 ASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEA 1362


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/219 (21%), Positives = 73/219 (33%), Gaps = 23/219 (10%)

Query: 304 IASLGSSDLLPQEHILLRTRPWLQ-ELSMGSPGPVTNKATKILRHFEASCGQLSPARGTS 362
           I +L +   LPQ    + +R  +    S+ +  PV + A +       +    +PA  +S
Sbjct: 123 ITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS 182

Query: 363 AEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDA 422
           + P  T A P      T A P   +         TP ++    PSS  P      PP  +
Sbjct: 183 SAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 423 SPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRL 482
           +  PAP         L+ S       +P    +    PSS +             A P  
Sbjct: 243 ATTPAP---------LSSSAPPETTAVPPTPSATTLDPSSAS-------------APPET 280

Query: 483 VGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFA 521
             A      + P  P +P       A    P S P+  A
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLA 319



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 6/101 (5%)

Query: 356 SPARGTSAEPGPTAALPGPSDL-----LTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
           +P   T+  P P+A    PS        T A P P +     P S  P  + + AP +  
Sbjct: 253 APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTA-APITTP 311

Query: 411 PSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPG 451
            SSP    P  +    AP   +        +   +P   PG
Sbjct: 312 NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPG 352



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 23/86 (26%)

Query: 351 SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
           S   L P+   SA P  TAA P PS                   ++TP    SPAP    
Sbjct: 265 SATTLDPS-SASAPPETTAAPPTPS-------------------ATTPAPPSSPAPQE-- 302

Query: 411 PSSPVPTPPPDASPIPAPGDPSEAEA 436
            ++  P   P++SP     D SE  A
Sbjct: 303 -TTAAPITTPNSSPTTLAPDTSETSA 327


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/219 (21%), Positives = 73/219 (33%), Gaps = 23/219 (10%)

Query: 304 IASLGSSDLLPQEHILLRTRPWLQ-ELSMGSPGPVTNKATKILRHFEASCGQLSPARGTS 362
           I +L +   LPQ    + +R  +    S+ +  PV + A +       +    +PA  +S
Sbjct: 123 ITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS 182

Query: 363 AEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDA 422
           + P  T A P      T A P   +         TP ++    PSS  P      PP  +
Sbjct: 183 SAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 423 SPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRL 482
           +  PAP         L+ S       +P    +    PSS +             A P  
Sbjct: 243 ATTPAP---------LSSSAPPETTAVPPTPSATTLDPSSAS-------------APPET 280

Query: 483 VGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFA 521
             A      + P  P +P       A    P S P+  A
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLA 319



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 6/101 (5%)

Query: 356 SPARGTSAEPGPTAALPGPSDL-----LTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
           +P   T+  P P+A    PS        T A P P +     P S  P  + + AP +  
Sbjct: 253 APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTA-APITTP 311

Query: 411 PSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPG 451
            SSP    P  +    AP   +        +   +P   PG
Sbjct: 312 NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPG 352



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 23/86 (26%)

Query: 351 SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
           S   L P+   SA P  TAA P PS                   ++TP    SPAP    
Sbjct: 265 SATTLDPS-SASAPPETTAAPPTPS-------------------ATTPAPPSSPAPQE-- 302

Query: 411 PSSPVPTPPPDASPIPAPGDPSEAEA 436
            ++  P   P++SP     D SE  A
Sbjct: 303 -TTAAPITTPNSSPTTLAPDTSETSA 327


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/219 (21%), Positives = 73/219 (33%), Gaps = 23/219 (10%)

Query: 304 IASLGSSDLLPQEHILLRTRPWLQ-ELSMGSPGPVTNKATKILRHFEASCGQLSPARGTS 362
           I +L +   LPQ    + +R  +    S+ +  PV + A +       +    +PA  +S
Sbjct: 123 ITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS 182

Query: 363 AEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDA 422
           + P  T A P      T A P   +         TP ++    PSS  P      PP  +
Sbjct: 183 SAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242

Query: 423 SPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRL 482
           +  PAP         L+ S       +P    +    PSS +             A P  
Sbjct: 243 ATTPAP---------LSSSAPPETTAVPPTPSATTLDPSSAS-------------APPET 280

Query: 483 VGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFA 521
             A      + P  P +P       A    P S P+  A
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLA 319



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 6/101 (5%)

Query: 356 SPARGTSAEPGPTAALPGPSDL-----LTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
           +P   T+  P P+A    PS        T A P P +     P S  P  + + AP +  
Sbjct: 253 APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTA-APITTP 311

Query: 411 PSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPG 451
            SSP    P  +    AP   +        +   +P   PG
Sbjct: 312 NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPG 352



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 23/86 (26%)

Query: 351 SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGM 410
           S   L P+   SA P  TAA P PS                   ++TP    SPAP    
Sbjct: 265 SATTLDPS-SASAPPETTAAPPTPS-------------------ATTPAPPSSPAPQE-- 302

Query: 411 PSSPVPTPPPDASPIPAPGDPSEAEA 436
            ++  P   P++SP     D SE  A
Sbjct: 303 -TTAAPITTPNSSPTTLAPDTSETSA 327


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 47/165 (28%), Positives = 59/165 (35%), Gaps = 23/165 (13%)

Query: 357 PARGTSAEPGPTAALPGPSDLLTD---AVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSS 413
           PA G    P   ++L      L D   A P      FL PL     ++    P  G P +
Sbjct: 725 PALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMG---AAAPQYPGRGPPPA 781

Query: 414 PVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPG-GTDSPKRGPSSCAWSRDSLFA 472
           P P PPP  +P      P    A  +          PG G  SP   P    +  ++ F+
Sbjct: 782 PPPPPPPPRAPADPAASPDPPSAVAS----------PGSGLSSPGPKPGDSGYETETPFS 831

Query: 473 GMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEP 517
                A P   G GAA  E  P  PRAP       A + PP   P
Sbjct: 832 PEG--AFP---GGGAAEEEGVP-RPRAPPEPPDPGAPRPPPDPGP 870



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 44/181 (24%), Positives = 58/181 (32%), Gaps = 44/181 (24%)

Query: 287 CHLRGTSECTQLRALCAIASLGSSDLL-----PQEHILLRT-RPWLQELSMGSPGPVTNK 340
           C   G   C  L    A+A  G    L     P++   LR  R  L +L M  P    + 
Sbjct: 701 CSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPA---SA 757

Query: 341 ATKILRHFEASCGQLSPARGT-----------------SAEPGPTAALPGPSDLLTDAVP 383
             + L     +     P RG                  +A P P +A+  P   L+   P
Sbjct: 758 PPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGP 817

Query: 384 LPGSQVFLQPLSSTPVSSRSPAPSSGM---------------PSSPVPTPPPDASPIPAP 428
            PG   +    + TP S     P  G                P    P PPPD  P+P P
Sbjct: 818 KPGDSGYE---TETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLP 874

Query: 429 G 429
           G
Sbjct: 875 G 875



 Score = 32.7 bits (73), Expect = 0.83
 Identities = 41/146 (28%), Positives = 48/146 (32%), Gaps = 18/146 (12%)

Query: 367 PTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIP 426
           P A  P  SDL      L         LS  P   R P P       P P P P A   P
Sbjct: 423 PPAQRPSASDLQLQLTYL---------LSERP--PRPPPPPPPPRDGPFPWPWPPAHSAP 471

Query: 427 APGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAG 486
            PG  S     L       P+ +   T+S +     C W +    AG       R  GA 
Sbjct: 472 RPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAG-------RGGGAP 524

Query: 487 AAAGESCPDAPRAPQTSSQRTAAKEP 512
           A    S P AP A  ++    A   P
Sbjct: 525 AWQPASAPPAPHANPSNPFYEALSTP 550



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 44/167 (26%), Positives = 57/167 (34%), Gaps = 30/167 (17%)

Query: 325  WLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLL------ 378
            W    ++G P P T+     L    A    +S   G    PGP    P    L       
Sbjct: 1066 WGPAPTIGEPAPETS-----LERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERR 1120

Query: 379  ---TDAVP-LPGS-QVFLQPLSSTPVSSRSPAPSSGMPSSPV-----------PTPPPDA 422
               T   P  PG+ ++ L      PV + + AP  G P S V           P PPP  
Sbjct: 1121 APETGGAPRAPGAGRLDLGSGGRAPVGTGT-APGGG-PGSGVDAKAGWVDNTRPQPPPPP 1178

Query: 423  SPIPAPGDPSEAEARLAESR-RWRPERIPGGTDSPKRGPSSCAWSRD 468
             P P    P   E     +R    PE  PG  DS   G ++ +   D
Sbjct: 1179 LPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGD 1225


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,155,341
Number of Sequences: 37866
Number of extensions: 1610334
Number of successful extensions: 18410
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 309
Number of HSP's successfully gapped in prelim test: 1182
Number of HSP's that attempted gapping in prelim test: 10528
Number of HSP's gapped (non-prelim): 5969
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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