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Search of human proteins with 21389423
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo
sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sa... 677 0.0
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 64 2e-10
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 56 5e-08
gi|153792074 proline rich 12 [Homo sapiens] 56 5e-08
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 55 9e-08
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 55 1e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 55 1e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 54 2e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 53 3e-07
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 52 7e-07
gi|19924099 synapsin I isoform Ia [Homo sapiens] 52 7e-07
gi|19924097 synapsin I isoform Ib [Homo sapiens] 52 7e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 51 1e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 51 1e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 51 1e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 51 1e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 2e-06
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-06
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 50 2e-06
gi|209529739 hypothetical protein LOC100132247 [Homo sapiens] 50 3e-06
gi|157074225 nuclear pore complex interacting protein-like 3 [Ho... 50 3e-06
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 50 3e-06
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 50 4e-06
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 49 5e-06
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 49 6e-06
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 49 6e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 49 8e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 48 1e-05
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 48 1e-05
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 48 1e-05
>gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo
sapiens]
Length = 331
Score = 677 bits (1747), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MSMTTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVD 60
MSMTTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVD
Sbjct: 1 MSMTTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVD 60
Query: 61 TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWG 120
TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWG
Sbjct: 61 TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWG 120
Query: 121 DLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFE 180
DLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFE
Sbjct: 121 DLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFE 180
Query: 181 AQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPR 240
AQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPR
Sbjct: 181 AQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPR 240
Query: 241 REGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEP 300
REGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEP
Sbjct: 241 REGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEP 300
Query: 301 RKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD 331
RKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD
Sbjct: 301 RKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD 331
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 63.5 bits (153), Expect = 2e-10
Identities = 69/315 (21%), Positives = 108/315 (34%), Gaps = 61/315 (19%)
Query: 19 QALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARG---- 74
Q+ D + + ++++R + +G V + + S P+K +KE + RG
Sbjct: 491 QSSSDSGSSSSSEDERPKRSH--VKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR 548
Query: 75 TPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLV 134
+P R + SP P R++ T PP + P PP
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP---------------------- 586
Query: 135 ALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAE 194
R P + + P R +SP P + +A PS PP R
Sbjct: 587 ----------RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVS 636
Query: 195 AEVRPKIPGS-----REAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEK 249
PK S R + + + G + + RE R P+ K
Sbjct: 637 HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR----------------SPQPNK 680
Query: 250 PRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSP 309
R P+ P+ P R + PQR +S RP R SR EP+K + SP
Sbjct: 681 -RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP 739
Query: 310 RRPDEEQRPGSRQKL 324
P +R S + +
Sbjct: 740 -SPQSVRRVSSSRSV 753
Score = 45.8 bits (107), Expect = 5e-05
Identities = 40/170 (23%), Positives = 67/170 (39%), Gaps = 12/170 (7%)
Query: 155 QARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDE-E 213
++R P S +PR SSP+ + + S +PR + R P + + E
Sbjct: 168 RSRSPRRRKSRSPSPRRRSSPVRR---ERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 214 EPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREP 273
EP E ++ + +D +P +P++ P K + +KE+ + R R+ +
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
Query: 274 REALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQK 323
R R S R SR PR RRP +RP R++
Sbjct: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPR--------RRPSPRRRPSPRRR 326
Score = 45.8 bits (107), Expect = 5e-05
Identities = 70/318 (22%), Positives = 120/318 (37%), Gaps = 52/318 (16%)
Query: 28 AETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGA 87
++ ++++ PR + S S + PS TRP++ + + +P +
Sbjct: 265 SKKEKEKEKTRPR-SRSRSKSRSRTRSRSPS-HTRPRRRHRSRSRSYSP-------RRRP 315
Query: 88 SPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDA 147
SPR P+ ++ PP + PPPP P S +L GS+
Sbjct: 316 SPRRRPSPRRR--TPPRRMPPPPRHRRSRSPVRRRR-------RSSASLSGSS------- 359
Query: 148 VPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREA 207
++ ++R P P P+ SSP K +P ++PP R RP P +
Sbjct: 360 -SSSSSSRSRSP-----PKKPPKRTSSPPRKTRRLSPSASPPRRRH----RPSPPATPPP 409
Query: 208 AENDEEEPGEATGEAVREDRVTLA-DRGPKERPRREGKPRKEKPRKEERPKK-ERPRKEE 265
P ++ R+ RV+++ R + + +G ++E P +P+K E EE
Sbjct: 410 KTRHSPTPQQS--NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE 467
Query: 266 RPRAAREPREALPQRWE--------SREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQR 317
+++ QR + S + G + D R K V RR R
Sbjct: 468 DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSR 527
Query: 318 -----PGSRQKLRAGKGR 330
P RQK + +GR
Sbjct: 528 SASPSPRKRQKETSPRGR 545
Score = 44.7 bits (104), Expect = 1e-04
Identities = 65/290 (22%), Positives = 98/290 (33%), Gaps = 42/290 (14%)
Query: 31 QEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPR 90
+ R+ R S S+ S + + PKK P +P RL SP
Sbjct: 339 RRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK---PPKRTSSPPRKTRRL----SPS 391
Query: 91 SVPARKKAQTAPPLQPPP-----PPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCR 145
+ P R++ + +PP PPP P P S +S++ + G+
Sbjct: 392 ASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT------ 445
Query: 146 DAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSR 205
E PS AP+ L E++ A + R +
Sbjct: 446 --------------EKRESPSPAPKPRKVELS--ESEEDKGGKMAAADSVQQRRQYRRQN 489
Query: 206 EAAENDEEEPGEATGEAVREDRVTLADRGPKER--PRREGKPRKEKPRKEERPKKERPRK 263
+ + +D + E + V + G + R P R P K +KE P+ R R
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549
Query: 264 EERP--RAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRR 311
P R R P A P R R P R + PR++ SPRR
Sbjct: 550 PSPPPTRRRRSPSPAPPPR--RRRTPTPPPRRRTPSPPPRRRSP--SPRR 595
Score = 36.6 bits (83), Expect = 0.032
Identities = 58/269 (21%), Positives = 93/269 (34%), Gaps = 61/269 (22%)
Query: 57 PSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPP-----LQPPPPPP 111
P+ R ++ P R TP R S P +++ +PP PPPPP
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622
Query: 112 ALSEELPWGDLSLN--------KCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWV 163
+ P ++ V L S + + + P + +AR P+P
Sbjct: 623 RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHR--KGSSPSRSTREARSPQPNK 680
Query: 164 --PPSSAPREP---SSPLPKFEA--------QAP-PSAPPAPRAEAEVRPK--------- 200
PS PR P SSP P Q+P PS P R PK
Sbjct: 681 RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Query: 201 ------------IPGSRE-AAENDEEEPGEATGEA----------VREDRVTLADRGPKE 237
+ GS E AA+ P ++ V++ + P
Sbjct: 741 PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800
Query: 238 RPRREGKPRKEKPRKEERPKKERPRKEER 266
+EG +K+K +K+++ KK++ K+ +
Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDKKHKKHK 829
Score = 35.8 bits (81), Expect = 0.054
Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 27/188 (14%)
Query: 155 QARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPA--------PRAEAEVRPKIPGSRE 206
++R P P P + P P P + + P P+ E PK P +
Sbjct: 206 KSRSPSP--APEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEK 263
Query: 207 AAENDEE-EPGEATGEAVREDRVTLADRGPKE-RPRREGKPRKEK--PRKEERPKKE-RP 261
++ ++E E + + R R P RPRR + R PR+ P++ P
Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSP 323
Query: 262 RKEERPRAAREP----REALPQRWESRE----GGHRPWARDSRDAEPRKKQAWVSPRRPD 313
R+ PR P R P R R G + SR P KK P+R
Sbjct: 324 RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK----PPKRTS 379
Query: 314 EEQRPGSR 321
R R
Sbjct: 380 SPPRKTRR 387
Score = 31.6 bits (70), Expect = 1.0
Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 223 VREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAARE--PREALPQR 280
+ ++++ + +++ +R+ + ++ K ER + R RK P R P +R
Sbjct: 136 IEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKR 195
Query: 281 WESREGGHRPWARDSRDAEPRKKQAWVSPRRPD 313
SR HR +R A +K++ +P P+
Sbjct: 196 SHSRSPRHRTKSRSPSPAPEKKEK---TPELPE 225
Score = 29.3 bits (64), Expect = 5.1
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 8/85 (9%)
Query: 236 KERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPRE--ALPQRWESREGGHRPWAR 293
K+R + K K + E++ K+++ KE ++RE RE P+R +SR P R
Sbjct: 132 KQRQIEQEKLASMKKQDEDKDKRDKEEKE----SSREKRERSRSPRRRKSRSPS--PRRR 185
Query: 294 DSRDAEPRKKQAWVSPRRPDEEQRP 318
S RK+ SPR + + P
Sbjct: 186 SSPVRRERKRSHSRSPRHRTKSRSP 210
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 55.8 bits (133), Expect = 5e-08
Identities = 73/295 (24%), Positives = 107/295 (36%), Gaps = 55/295 (18%)
Query: 48 PHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPP 107
P DS++ EG V +P++ + + PG G + R PA TA PL P
Sbjct: 386 PGDSEIEEGEIV--QPEEEPRLALSLFRPG--------GRAARPTPAASATPTAQPLPQP 435
Query: 108 PPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPW-VPPS 166
P P A P GD F GE ALQ + EP PP+
Sbjct: 436 PAPRA-----PEGD------------------DFLSLHAESDGEGALQVDLGEPAPAPPA 472
Query: 167 SAPREPSSPL---------PKFEAQAPPSAP-PAPRAEAEVRPKIPGSREAAENDEEEPG 216
+ R L ++ ++P AP PAP A A P +R+ + + + G
Sbjct: 473 ADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAG-----PPTRKKSRRERKRSG 527
Query: 217 EATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREA 276
EA A A P + K + + RK R+ R R+
Sbjct: 528 EAKEAASSSSGTQPAPPAPAS--PWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRR 585
Query: 277 LPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD 331
+ + R GG +R SR E R+++ + P SR++ GK RD
Sbjct: 586 RSRSTDRRRGG----SRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRD 636
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/196 (20%), Positives = 67/196 (34%), Gaps = 36/196 (18%)
Query: 74 GTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASL 133
GT G A +S S P+ + ++P PPPPPP
Sbjct: 178 GTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPP---------------------- 215
Query: 134 VALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRA 193
A P A + + +P+ P A P +P K++ P + P+ A
Sbjct: 216 -------------APPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSA 262
Query: 194 EAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRG-PKERPRREGKPRKEKPRK 252
+ E E +EE+ E G + R++ G + + P E PR
Sbjct: 263 GTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRP 322
Query: 253 EERPKKERPRKEERPR 268
+ +P + P P+
Sbjct: 323 DAQPTQPTPAPGTPPQ 338
Score = 32.7 bits (73), Expect = 0.46
Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 31/147 (21%)
Query: 1 MSMTTRAWEELDGGLGSC-----QALEDHSALAETQEDRASATPRLADSGSVPHDSQV-- 53
+S TT A + GLGS + E S + E + + A + P ++V
Sbjct: 845 VSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKA 904
Query: 54 ------AEGPSVDTRPKKMEKEPAARGTPGT--GKERLKA-------------GASPRSV 92
+G T+P K K+ + G G G+ LK GA S
Sbjct: 905 KAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSW 964
Query: 93 PARKKAQTAPPLQPP---PPPPALSEE 116
++A P PP PPPPAL+ +
Sbjct: 965 SGEERAAKVPSTPPPKAAPPPPALTPD 991
Score = 28.9 bits (63), Expect = 6.6
Identities = 53/230 (23%), Positives = 77/230 (33%), Gaps = 47/230 (20%)
Query: 41 LADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPR---------- 90
L DS + + + + D R ++ G+ ++ L G R
Sbjct: 731 LYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDR 790
Query: 91 -SVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAV- 148
S AR ++AP PPP PP S S + C + V L L R+ V
Sbjct: 791 SSKKARPPKESAPSSGPPPKPPVSSGS--GSSSSSSSC--SSRKVKLQSKVAVLIREGVS 846
Query: 149 ---PGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSR 205
P + A A + V S RE SP K P RA E+ PGS
Sbjct: 847 STTPAKDAASAGLGSIGV-KFSRDRESRSPFLK----------PDERAPTEMAKAAPGST 895
Query: 206 EAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEER 255
+ + + A G K+ +GK + K RK+ R
Sbjct: 896 KPKKTKVK-----------------AKAGAKKTKGTKGKTKPSKTRKKVR 928
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 55.8 bits (133), Expect = 5e-08
Identities = 60/217 (27%), Positives = 80/217 (36%), Gaps = 50/217 (23%)
Query: 29 ETQEDRASATPRLADSGSV-PHDSQVAEGPSVDTR-----PKKMEKEPAARGTPGTGKER 82
+ QE +SA L D P D+ +GP + P + P+A GT +
Sbjct: 1393 DLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSN-GTPEPP 1451
Query: 83 LKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQ 142
L P + P Q PP PPPP PAL P LVA S+
Sbjct: 1452 LLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPP--------------LVAPTPSS-- 1495
Query: 143 LCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPP-APRAEAEVRPKI 201
P P +PP P PS P P A AP +APP P A + P++
Sbjct: 1496 ---------------PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
Query: 202 PGSR-----------EAAENDEEEPGEATGEAVREDR 227
P +R +EE GE+ GE + +R
Sbjct: 1541 PDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRER 1577
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/194 (24%), Positives = 75/194 (38%), Gaps = 40/194 (20%)
Query: 160 EPWVPPSSAPR---EPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPG 216
+PW P R + +P+ + APP PAP +P+ P + + E+ P
Sbjct: 1665 KPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAP----PPKPETPEKTTSEKPPEQTPE 1720
Query: 217 EATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREA 276
A E ++ +L KE+ +E R E+P + ER R + ER A +P
Sbjct: 1721 TAMPEPPAPEKPSLLRPVEKEK-EKEKVTRGERPLRGERATSGRQTRPERSLATGQPA-- 1777
Query: 277 LPQRWESREGGHRPWARDSRDAEPRKKQAWV----------------------SPRRPDE 314
SR RP + + P+K++ W+ SP P E
Sbjct: 1778 -----TSRLPKARP-TKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSE 1831
Query: 315 EQR--PGSRQKLRA 326
++R PG K RA
Sbjct: 1832 DERAVPGRLLKTRA 1845
Score = 39.7 bits (91), Expect = 0.004
Identities = 57/227 (25%), Positives = 80/227 (35%), Gaps = 36/227 (15%)
Query: 75 TPGTGKERLKAGASPRSVPARKKA-------QTAPPLQPPPPPPALSEELPWGDLSLNKC 127
TPG G + K P +V A Q APP PPPPPP P G L+
Sbjct: 1005 TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIF 1064
Query: 128 LVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSA 187
L S+F L R PP P++ + +FEA +
Sbjct: 1065 CSTKPKKLLKTSSFHLLRRR---------------DPPFQTPKKLYAQEYEFEADEDKAD 1109
Query: 188 PPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRK 247
P A++R + + P + + + + GP + PRR G+
Sbjct: 1110 VP-----ADIRLNPRRLPDLVSSCRSRPALS---PLGDIDFCPPNPGP-DGPRRRGR--- 1157
Query: 248 EKPRKEERPKKERPRKEERPRAAREPREALPQRWES-REGGHRPWAR 293
KP K +R RPR R R P A P + +G +P R
Sbjct: 1158 -KPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGR 1203
Score = 30.0 bits (66), Expect = 3.0
Identities = 32/116 (27%), Positives = 42/116 (36%), Gaps = 16/116 (13%)
Query: 79 GKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLG 138
G ERL AG AQT P PP PP LP +L+A
Sbjct: 204 GFERL-AGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLP----------TQFNLLASSS 252
Query: 139 SAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFE----AQAPPSAPPA 190
+A + P P P P + PR+ + + ++ AQ PP PPA
Sbjct: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQ-DTVIKHYQRPASAQPPPPPPPA 307
Score = 29.6 bits (65), Expect = 3.9
Identities = 45/179 (25%), Positives = 61/179 (34%), Gaps = 33/179 (18%)
Query: 106 PPPPPPAL--SEELPWG--------DLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQ 155
PPPPPP ++ P G DL L ++ LL S P + +
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPL---VLPPPPPQLLPSVLSHAPSPSPSASKVG 820
Query: 156 ARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAP-RAEAEVR-----PKIPGSREAAE 209
+ EP AP+ P P PP PP P + EA +R P P R E
Sbjct: 821 VHLLEP-ATRDGAPQPPPPP--------PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE 871
Query: 210 NDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPR 268
+ PG A++E L P G P E + P+ + PR
Sbjct: 872 ESLDPPG-----AMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPR 925
Score = 28.9 bits (63), Expect = 6.6
Identities = 11/25 (44%), Positives = 14/25 (56%)
Query: 93 PARKKAQTAPPLQPPPPPPALSEEL 117
PA + PP PPPPPP + +L
Sbjct: 826 PATRDGAPQPPPPPPPPPPPMPLQL 850
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 55.1 bits (131), Expect = 9e-08
Identities = 81/323 (25%), Positives = 133/323 (41%), Gaps = 39/323 (12%)
Query: 20 ALEDHSAL-AETQEDRASATPRLADSG-------SVPHDSQVAEGPSVDTRPKKMEKEPA 71
+L DH+ L +E R + + D+G ++ +D G ++ P K E+E
Sbjct: 129 SLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETLSDIPCKTEEEGV 188
Query: 72 ARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKC--LV 129
G G G+ SPRS P + + P + P + SE G L K +V
Sbjct: 189 GCG--GAGRRGDSQECSPRSCP---ELTSGPRMCPRKEQDSWSEA--GGILFKGKVPMVV 241
Query: 130 LASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPS----SPLPKFEAQAPP 185
L ++A+ + ++P + PE V S P E S S L + + P
Sbjct: 242 LQDILAVRPPQIK----SLPATPQGKNMTPESEVL-ESFPEEDSVLSHSSLSSPSSTSSP 296
Query: 186 SAPPAPRAEAEVRPKIPGS---REAAENDEEEPGEATGEAVREDRVTL-------ADRGP 235
PPAP + P S R + + E ++ D+ L A+R
Sbjct: 297 EGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREE 356
Query: 236 KERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPRE-ALPQRWESREGGHRPWARD 294
KE+ + E K KE+ +K++ +KE KE R + ++ +E A QR + R A +
Sbjct: 357 KEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALE 416
Query: 295 SRDAEPRKKQAWVSPRRPDEEQR 317
++ E RKK+ R +EE+R
Sbjct: 417 AKLEEKRKKEE--EKRLREEEKR 437
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 180 EAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKE-- 237
+ +APP P PR PG R E P E T + ++ + + PKE
Sbjct: 53 DVEAPPPPEPTPRVRKAQAGGKPGKRPGTA--AEVPPEKTKDKGKKGKKDKGPKVPKESL 110
Query: 238 ----RPRREGK---PRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRP 290
RP ++GK P+ K KE+ PK + KE+ P+A ++P+E P+ + G RP
Sbjct: 111 EGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRP 170
Score = 37.7 bits (86), Expect = 0.014
Identities = 70/277 (25%), Positives = 97/277 (35%), Gaps = 65/277 (23%)
Query: 29 ETQEDRASATP--------RLADSGSVP--HDSQVAEGPSVDTRPK----KMEKEP---- 70
E +ED A P R A +G P AE P T+ K K +K P
Sbjct: 48 EPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPK 107
Query: 71 ----AARGTPGTGKERL-KAGASPRSVP--ARKKAQTAPPL---QPPPPPPALSEELPWG 120
+ P GKE+ KA P+ P A KK + PP +P PP +++ P G
Sbjct: 108 ESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSG 167
Query: 121 DLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFE 180
+ +LA P E P P P P+E +PL
Sbjct: 168 ----KRPPILA-----------------PSETLEWPLPPPPSPGPEELPQEGGAPLSNNW 206
Query: 181 AQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPR 240
P E V +RE EEE + T + D++ D E R
Sbjct: 207 QN--------PGEETHVE-----AREHQPEPEEETEQPTLDY--NDQIEREDYEDFEYIR 251
Query: 241 REGKPRKEKPRKEERPKKERPRKEERPRAAREPREAL 277
R+ +PR P + RP++ P E A P E +
Sbjct: 252 RQKQPRPP-PSRRRRPERVWPEPPEEKAPAPAPEERI 287
Score = 37.0 bits (84), Expect = 0.024
Identities = 68/296 (22%), Positives = 106/296 (35%), Gaps = 53/296 (17%)
Query: 31 QEDRASATPRLADSGSVPHDSQVAEGPSVDTR-----PKKMEKEPAARGTPGTGKERLKA 85
++D+ P+ + GS + E P T+ P K K+P + T K + K
Sbjct: 98 KKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKP 157
Query: 86 GASPRSVPARKKAQTAPPLQ------PPPPPPALSEELPWGDLSLN--------KCLVLA 131
+ + P+ K+ P + PPPP P E G L+ + V A
Sbjct: 158 PKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEA 217
Query: 132 ----------SLVALLGSAFQLCR-DAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFE 180
+ L Q+ R D E + + P P P S R P P+
Sbjct: 218 REHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRP---PPSRRRRPERVWPEPP 274
Query: 181 AQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAV--REDRVTLADRGPKER 238
+ P+ P R E V+P +P P G + +D P ++
Sbjct: 275 EEKAPAPAPEERIEPPVKPLLP---------PLPPDYGDGYVIPNYDDMDYYFGPPPPQK 325
Query: 239 PRREGKPRKE-----KPRKEERPKKERPRK--EERPRAAREPR--EALPQRWESRE 285
P E + +E KP+KE+ KE K E+ + +EPR E L + W E
Sbjct: 326 PDAERQTDEEKEELKKPKKEDSSPKEETDKWAVEKGKDHKEPRKGEELEEEWTPTE 381
Score = 30.8 bits (68), Expect = 1.7
Identities = 34/157 (21%), Positives = 58/157 (36%), Gaps = 9/157 (5%)
Query: 165 PSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVR 224
P A ++P PK A P P P+A + + K P + + + + P A E +
Sbjct: 124 PPKATKKPKEKPPK--ATKKPKEKP-PKATKKPKEKPPKATKKPPSGKRPPILAPSETLE 180
Query: 225 EDRVTLADRGPKERPRREGKPRKEKPRK--EERPKKERPRKEERPRAAREPREALPQRWE 282
GP+E P+ G P + EE + R + E +P + E
Sbjct: 181 WPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIE 240
Query: 283 SREGGHRPWARDSRDAEP----RKKQAWVSPRRPDEE 315
+ + R + P R++ V P P+E+
Sbjct: 241 REDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEK 277
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 54.7 bits (130), Expect = 1e-07
Identities = 43/157 (27%), Positives = 67/157 (42%), Gaps = 17/157 (10%)
Query: 192 RAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPR 251
+ E R K RE E E GE +E+R R KE E K +++K
Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119
Query: 252 KEERPK-----KERPRKEERPRAAREPREALPQ------------RWESREGGHRPWARD 294
K+ER + KER RKEER R R+ RE + + E ++ G + R
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 295 SRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD 331
++ + RKK+ R E +R R++ + K ++
Sbjct: 180 EKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Score = 51.6 bits (122), Expect = 1e-06
Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 7/133 (5%)
Query: 205 REAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPR---KEKPRKEERPKKERP 261
R EN E E E + +++R + G KER R+E + R KE+ RK+E +KER
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEG-KERERKEERKREERKERERKKEEREKERE 159
Query: 262 RKEERPRAAREPREALPQRWESREGGHRPWARDSRDAE---PRKKQAWVSPRRPDEEQRP 318
RKE + R ++ E +R E + R+ ++ + RK++ R +E+R
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK 219
Query: 319 GSRQKLRAGKGRD 331
RQK R R+
Sbjct: 220 KERQKDRQTNWRE 232
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
Query: 192 RAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRK--EK 249
R E R + + +E E E + +R + ++ +ER +E K RK E+
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK-EEERKEKERKERKKRER 191
Query: 250 PRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKK 303
RKE + ++ER + ER + ++ E +R + R+ R R R+ + RKK
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 45.4 bits (106), Expect = 7e-05
Identities = 41/144 (28%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 191 PRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKP 250
P ++E+R + E +E E E R +R KER R GK K+
Sbjct: 32 PGWQSEIREREREIETRKEGKKERESERKKE--RREREKRKREREKERKRERGKKEKKGE 89
Query: 251 R-KEERPKKERPR----KEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQA 305
R KEER +K+R R KE + R+ +E + S+EG R ++ R E RK++
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE-RKEERKREERKERE 148
Query: 306 WVSPRRPDEEQRPGSRQKLRAGKG 329
R E +R +++ R G
Sbjct: 149 RKKEEREKERERKERKKRERKQVG 172
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/130 (23%), Positives = 54/130 (41%)
Query: 194 EAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKE 253
E E R K + E + E E RE+R + + RE K RK++ RK+
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQ 170
Query: 254 ERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPD 313
K+E +++ER + R ++ E R ++ + E RKK+ +
Sbjct: 171 VGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNW 230
Query: 314 EEQRPGSRQK 323
E+ G R++
Sbjct: 231 REKERGKRER 240
Score = 42.7 bits (99), Expect = 4e-04
Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 5/120 (4%)
Query: 214 EPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPR----KEERPKKERPRKEERPRA 269
+PG + RE + G KER K R+E+ + +E+ K+ER +KE++
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Query: 270 AREPREALPQRWE-SREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGK 328
+E RE +R E + G R ++ + R + + R +E+R +K R K
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 206 EAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKER--PRK 263
E E + E G+ RE ++R + R R + K +EK RK ER KKE+ RK
Sbjct: 37 EIREREREIETRKEGKKERE-----SERKKERREREKRKREREKERKRERGKKEKKGERK 91
Query: 264 EERPRAAREPREALPQRWESRE----GGHRPWARDSRDAEPR-KKQAWVSPRRPDEEQRP 318
+E + RE + E +E + R S++ + R +K+ R + E++
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 319 GSRQKLRAGKGR 330
R+K R K R
Sbjct: 152 EEREKERERKER 163
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 53.9 bits (128), Expect = 2e-07
Identities = 74/302 (24%), Positives = 113/302 (37%), Gaps = 37/302 (12%)
Query: 39 PRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAAR--GTPGTGKERLKAGASPRSVPARK 96
P+ + VP A+ P V PKK+ E R P ++ P+ V K
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEV---PKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK 10508
Query: 97 KAQTAPPLQPPPPPP----ALSEELPWGDLSL---NKCLVLASLVALLGSAFQLCRDAVP 149
K P +P PPP A E +P + + K V + V + A AVP
Sbjct: 10509 KVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKA------AVP 10562
Query: 150 GEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPP------APRAEAEVRPK--- 200
+ +A P+P PP P P +P+ + A P P P A EV P+
Sbjct: 10563 EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKV 10622
Query: 201 -IPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKK- 258
+P ++ + P E AV E +V A E P E E+ EE P +
Sbjct: 10623 PVPPPKKPEVPPTKVP-EVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEV 10681
Query: 259 -ERPRKEERPRAAREPREALPQRWESREGGHRP------WARDSRDAEPRKKQAWVSPRR 311
E P P+ P++ +P++ +P ++ P KK V P++
Sbjct: 10682 VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKK 10741
Query: 312 PD 313
P+
Sbjct: 10742 PE 10743
Score = 47.8 bits (112), Expect = 1e-05
Identities = 74/309 (23%), Positives = 112/309 (36%), Gaps = 38/309 (12%)
Query: 34 RASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVP 93
R P++ + P +VA P PKK+E P A P K+ + P VP
Sbjct: 9281 RVEPPPKVPELPEKPAPEEVAPVPI----PKKVE--PPAPKVPEVPKKPVPEEKKP--VP 9332
Query: 94 ARKKAQTAPPLQPPPP-------------------PPALSEELPWGDLSLNKCLVLASLV 134
KK APP P P PPA E+ G ++ K ++
Sbjct: 9333 VPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQRE 9392
Query: 135 ALLGSAF-QLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAP----PSAPP 189
A ++ + VP E R E PP P P P+P+ + P APP
Sbjct: 9393 ESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPP 9452
Query: 190 APRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEK 249
PRAE + + R A EE+ A + V R ++ E
Sbjct: 9453 -PRAEVSKKTVVEEKRFVA---EEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISV 9508
Query: 250 PRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSP 309
R+EER ++E E EP E + + + R A + E ++K+ + P
Sbjct: 9509 YREEEREEEEEAEVTEY-EVMEEPEEYVVEE-KLHIISKRVEAEPAEVTERQEKKIVLKP 9566
Query: 310 RRPDEEQRP 318
+ P + + P
Sbjct: 9567 KIPAKIEEP 9575
Score = 47.8 bits (112), Expect = 1e-05
Identities = 59/274 (21%), Positives = 99/274 (36%), Gaps = 53/274 (19%)
Query: 57 PSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEE 116
P ++ P ++ +EP E + P V + P + PP P ++
Sbjct: 10656 PKPESPPPEVFEEP----------EEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKK 10705
Query: 117 LPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVP-----EPWVPPSSAPRE 171
P ++VA + VP E + +VP +P PP+ P
Sbjct: 10706 AP-------------AVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV 10752
Query: 172 PSSPLPKFEAQAP--PSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVT 229
P +P+ + P P PPA E +P + EE+P E
Sbjct: 10753 PKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVL----------EEKPAVPVPERAESPPPE 10802
Query: 230 LADRGPKERPRREGKPRKEKP---RKEERPKKERPRKEERPRAAREPREALPQRWESREG 286
+ + + P E P +EKP +EE P+ P E EP++ +P++
Sbjct: 10803 VYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPE------EPKKIIPEK--KVPV 10854
Query: 287 GHRPWARDSRDAEPRK--KQAWVSPRRPDEEQRP 318
+P A ++ EP K ++ + PR P P
Sbjct: 10855 IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAP 10888
Score = 45.8 bits (107), Expect = 5e-05
Identities = 50/171 (29%), Positives = 77/171 (45%), Gaps = 14/171 (8%)
Query: 157 RVPEPWVPPSSAPREPSS-PLPKFEAQAPPSAPPAPRAEA-EVRPKIPGSREAAENDEEE 214
+VPE VP P E P+PK E APP P P+ E + +P +++ +
Sbjct: 9315 KVPE--VPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKV 9372
Query: 215 PGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEER-PRAAREP 273
P E V E+++T+ + + P + K+K +E +P PRKEE P + P
Sbjct: 9373 P-EVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPV---PRKEEEVPPPPKVP 9428
Query: 274 REALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKL 324
ALP++ E P + PR A VS + EE+R + +KL
Sbjct: 9429 --ALPKKPVPEEKVAVPVPVAKKAPPPR---AEVSKKTVVEEKRFVAEEKL 9474
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/165 (23%), Positives = 64/165 (38%), Gaps = 18/165 (10%)
Query: 156 ARVPEPWVPPSSAPREPSSPLP--KFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEE 213
A EP VPP + P EP +P K P APP E E K+ +
Sbjct: 10827 AEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPE---KVIEKPKLKPRPPP 10883
Query: 214 EPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREP 273
P E V+E L + P+K+ P K + P+K + P ++
Sbjct: 10884 PPPAPPKEDVKEKIFQL-----------KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKV 10932
Query: 274 REALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRP 318
R+ LP+R E + P +++ V P++ ++ ++P
Sbjct: 10933 RKLLPER--KPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKP 10975
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/183 (26%), Positives = 72/183 (39%), Gaps = 30/183 (16%)
Query: 149 PGEAALQARVPEPW-----VPPSSAPREPSSPLPKFEAQAPPSA----PPAPRAEAEVRP 199
P + + +VP P VPP P EP P+P E + PP P P E
Sbjct: 9584 PKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVP--EKKVPPKVIKMEEPLPAKVTERHM 9641
Query: 200 KIPGSREA--AENDEEEPGEAT-----GEAVREDRVTLADRGPKERPR-----------R 241
+I + A +E P +A AV E++V +E P +
Sbjct: 9642 QITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVK 9701
Query: 242 EGKPRKEKPRKEERPKKERPRKEERPRAAREPREALP-QRWESREGGHRPWARDSRDAEP 300
E K E P++E +P KE EE+ RA EA+ QR E E ++ + EP
Sbjct: 9702 EEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEP 9761
Query: 301 RKK 303
++
Sbjct: 9762 TEE 9764
Score = 39.3 bits (90), Expect = 0.005
Identities = 66/244 (27%), Positives = 90/244 (36%), Gaps = 39/244 (15%)
Query: 57 PSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPA--RKKAQTAPPLQPPP--PPPA 112
P V +P EK+P P K+ A P VP +K + P L P PPPA
Sbjct: 9951 PEVPRKPVPEEKKPV----PVPKKKE----APPAKVPEVPKKPEEKVPVLIPKKEKPPPA 10002
Query: 113 LSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPW-----VPPSS 167
E+P + K V V A VP + + +VP P PP+
Sbjct: 10003 KVPEVPKKPVPEEKVPVP---VPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAK 10059
Query: 168 APREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSRE------AAENDE----EEPGE 217
P P +P E + P P P+ PK+P RE A +E EE
Sbjct: 10060 VPEVPKKLIP--EEKKPT---PVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIV 10114
Query: 218 ATGEAVREDRVTLADRGPKERPRREGKPRKEK--PRKEERPKKERPRKEERPRAAREPRE 275
E + E+ L + E P +E+ P +EE P +E EE E E
Sbjct: 10115 PEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE--E 10172
Query: 276 ALPQ 279
LP+
Sbjct: 10173 VLPE 10176
Score = 39.3 bits (90), Expect = 0.005
Identities = 73/311 (23%), Positives = 109/311 (35%), Gaps = 59/311 (18%)
Query: 63 PKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPL-----QPPPPPPALSEE- 116
PKK+E PA P K+ + P VP KK + PP +P P P AL +E
Sbjct: 10050 PKKVEAPPAK--VPEVPKKLIPEEKKPTPVP--KKVEAPPPKVPKKREPVPVPVALPQEE 10105
Query: 117 --------LPWGDLSLNKCLVLASLVALLGSAFQLC---------RDAVPGEAAL----Q 155
+P ++ + VL +L ++ + VP E +
Sbjct: 10106 EVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEE 10165
Query: 156 ARVPEPWVPPSSAPREPSSP---------------LPKFEAQAPPSAPPAPRAEAEVRPK 200
VPE V P P+ P +PK E P P P+ E R
Sbjct: 10166 EFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRII 10225
Query: 201 IPGSREAAEND-EEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKE 259
+P E + EEP E E + E+ + P+E P E PR E KK
Sbjct: 10226 LPKEEEVLPVEVTEEPEE---EPISEEEI------PEEPPSIEEVEEVAPPRVPEVIKKA 10276
Query: 260 RPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPG 319
P E P + EA P + + + + P K V + P+++
Sbjct: 10277 VP---EAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVP 10333
Query: 320 SRQKLRAGKGR 330
++ + KGR
Sbjct: 10334 KKEAVPPAKGR 10344
Score = 38.9 bits (89), Expect = 0.006
Identities = 69/275 (25%), Positives = 93/275 (33%), Gaps = 52/275 (18%)
Query: 57 PSVDTRPKKM---EKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQP--PPPPP 111
P+V PKK+ +K P + K A P P +K P L+P PPPPP
Sbjct: 10837 PAVPEEPKKIIPEKKVPVIK----------KPEAPPPKEPEPEKVIEKPKLKPRPPPPPP 10886
Query: 112 ALSEELPWGDLSLNKCLVLASL--VALLGSAFQLCRDAVPG-----EAALQARVPEP--- 161
A +E + K + + + +L VPG L R PEP
Sbjct: 10887 APPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEE 10946
Query: 162 WVPPSSAPREPSSPLPKFEAQ---------APPSAPPAPRAEAEV------RPKIPGSRE 206
V S + P PK E + P PP P E EV KIP +
Sbjct: 10947 VVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK 11006
Query: 207 AAENDEEEPGEATGEAVREDRVTLADRGPKERPRRE-----------GKPRKEKPRKEER 255
E P A + + + P P GK + K KEE
Sbjct: 11007 VPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA 11066
Query: 256 PKKERPRKEERPRAAREPREALPQRWESREGGHRP 290
K + P K P+ P EA ++ GG +P
Sbjct: 11067 AKPKGPIKGV-PKKTPSPIEAERRKLRPGSGGEKP 11100
Score = 38.5 bits (88), Expect = 0.008
Identities = 50/240 (20%), Positives = 79/240 (32%), Gaps = 41/240 (17%)
Query: 49 HDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPAR--KKAQTAPPLQP 106
H+ + E P K + +EP + LK VP KK + PP P
Sbjct: 9782 HEEYITE-PEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVP 9840
Query: 107 PPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVP-- 164
P E++ R ++ Q P VP
Sbjct: 9841 EEPKKVFEEKI---------------------------RISITKREKEQVTEPAAKVPMK 9873
Query: 165 PSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPK-IPGSREAAENDEEEPGEATGEAV 223
P E P+P+ E P P P+ E+ P+ + E + EE E E +
Sbjct: 9874 PKRVVAEEKVPVPRKEVAPPVRVPEVPK---ELEPEEVAFEEEVVTHVEEYLVEEEEEYI 9930
Query: 224 REDRVTLADRG-----PKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALP 278
E+ + + P + P KP E+ + PKK+ + P ++P E +P
Sbjct: 9931 HEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVP 9990
Score = 36.2 bits (82), Expect = 0.042
Identities = 43/172 (25%), Positives = 58/172 (33%), Gaps = 42/172 (24%)
Query: 92 VPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE 151
V +K + P P PPPP EE+ VP
Sbjct: 10964 VEPKKLEKVKKPAVPEPPPPKPVEEVE-----------------------------VPTV 10994
Query: 152 AALQARVPEPWVPPSSAPREP---SSPLPKFEAQA-----PPSAPPAPRAEAEVRPKIPG 203
+ ++PEP P P P P PK EA+ PP P A V + G
Sbjct: 10995 TKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVG 11054
Query: 204 SREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRK--EKPRKE 253
+ A+ +EE + G + T P E RR+ +P EKP E
Sbjct: 11055 KKAEAKAPKEEAAKPKGPIKGVPKKT---PSPIEAERRKLRPGSGGEKPPDE 11103
Score = 32.0 bits (71), Expect = 0.78
Identities = 27/113 (23%), Positives = 44/113 (38%), Gaps = 5/113 (4%)
Query: 172 PSSPLPKFEAQAPPSAPPA---PRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRV 228
P P+P+ P APPA +A E + +P ++ + P E + R+
Sbjct: 9794 PVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRI 9853
Query: 229 TLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERP--RAAREPREALPQ 279
++ R ++ K + R K PRKE P R P+E P+
Sbjct: 9854 SITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPE 9906
Score = 28.9 bits (63), Expect = 6.6
Identities = 33/140 (23%), Positives = 49/140 (35%), Gaps = 15/140 (10%)
Query: 182 QAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRR 241
+ PP PP P++ + P I + A P + VR R P P R
Sbjct: 252 KTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRH------VRAPTPSPVR 305
Query: 242 EGKPRKEKPRKEERPKKE--RPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAE 299
P R + RK + A P +P W+ +EG + S +AE
Sbjct: 306 SVSPAARISTSPIRSVRSPLLMRKTQASTVATGPE--VPPPWK-QEG----YVASSSEAE 358
Query: 300 PRKKQAWVSPRRPDEEQRPG 319
R+ S + EE+ G
Sbjct: 359 MRETTLTTSTQIRTEERWEG 378
Score = 28.9 bits (63), Expect = 6.6
Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 2/63 (3%)
Query: 166 SSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVRE 225
S P PS P+ + APP P PR R + S + ++E + TG +
Sbjct: 30014 SGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV--SLAWSVPEDEGGSKVTGYLIEM 30071
Query: 226 DRV 228
+V
Sbjct: 30072 QKV 30074
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 53.1 bits (126), Expect = 3e-07
Identities = 75/320 (23%), Positives = 114/320 (35%), Gaps = 29/320 (9%)
Query: 25 SALAETQEDR-ASATPRLADSGSVPHDSQVAEGPSVDT-RPKKMEKEPAARGTPGTGKER 82
SA A+T A +P A D+ +E + T RP E +P K++
Sbjct: 281 SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK 340
Query: 83 -LKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAF 141
K ++ R P+ +++ T P +PP P P L+E L + L
Sbjct: 341 DKKEKSATRPSPSPERSSTGP--EPPAPTPLLAERHGGSPQPL-------ATTPLSQEPV 391
Query: 142 QLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKI 201
+A P + PE SS+ P SP P ++ S+P +P+
Sbjct: 392 NPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA----- 446
Query: 202 PGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPR-----REGKPRKEKPRKEERP 256
PGS + + G A R+ + R R + G+ R P K
Sbjct: 447 PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506
Query: 257 KKERPRKEERPRAAREPREALPQRWESREGGHRP-WARDSRDAEPR-----KKQAWVSPR 310
+ P+ A R R PQR RP W+R SR+ + R ++ R
Sbjct: 507 RSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSR-SRNTQRRGRSRSARRGRSHSR 565
Query: 311 RPDEEQRPGSRQKLRAGKGR 330
P R SR R G+ R
Sbjct: 566 SPATRGRSRSRTPARRGRSR 585
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/307 (22%), Positives = 105/307 (34%), Gaps = 21/307 (6%)
Query: 32 EDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGAS--P 89
+D+ A PR A SGS A P R + RG G ++ P
Sbjct: 1605 KDKPRAAPR-AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 90 RSVPARKKAQTAP-PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAV 148
+S AR+ ++++P P PP +L+ L S A S+ R
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA---SSSPETRSRT 1720
Query: 149 PGEAALQARV--PEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSRE 206
P V PEP S+ R S+ P+ + + P+P+ R + RE
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 207 AAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKP-RKEKPRKEERPKKERPRKEE 265
+ ++ R R R RR G P ++E + R+
Sbjct: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840
Query: 266 RPRAAREPREALPQRWESREGGHRPWARDSRDAEP------RKKQAWVSPRRPDEEQRPG 319
R R R +R SR PW R A P R + +S RR P
Sbjct: 1841 RSRTPPTSR----KRSRSRT-SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895
Query: 320 SRQKLRA 326
SR++ R+
Sbjct: 1896 SRRRSRS 1902
Score = 43.5 bits (101), Expect = 3e-04
Identities = 75/350 (21%), Positives = 117/350 (33%), Gaps = 40/350 (11%)
Query: 14 GLGSCQALEDHSALAETQE--DRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPA 71
G C + + AL +T R+ ++P L + P + SVD K + + P
Sbjct: 1476 GRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ--KTVARTPL 1533
Query: 72 A-RGTPGTGKER-LKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLV 129
R G+ +E +K ASP+ R ++ ++P + P ++
Sbjct: 1534 GQRSRSGSSQELDVKPSASPQE---RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
Query: 130 LASLVALLGSAFQLCRD---AVPGEAALQARVPEPWVP-PSSAPREPSS----------P 175
L+ + GS+ ++ +D A P + PEP P P + PR S P
Sbjct: 1591 LSPRRSRSGSSPEV-KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649
Query: 176 LPKFEAQAPPSAPPAPR-----AEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTL 230
++ P PP R + + PK E T +A R
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
Query: 231 ADRGPKER----PRREGKPRKEKPRKEERPKKER-------PRKEERPRAAREPREALPQ 279
A P+ R PR P P E+ + R PR + R R P
Sbjct: 1710 ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG 1769
Query: 280 RWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGKG 329
SR R R +R + S RR R ++ R G G
Sbjct: 1770 LQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 64/176 (36%), Gaps = 16/176 (9%)
Query: 148 VPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREA 207
V E AL+ RVP P P A RE P P + S+ + + + S +
Sbjct: 2570 VQPEVALK-RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628
Query: 208 AENDEEEPGEATGEAVREDRVTLADRGPKERPR-------REGKPRKEKPRK------EE 254
+ + ++ + + A GP+ P+ G+ R PRK +
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688
Query: 255 RPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPR 310
R P + RP PR+ Q S G R DSR ++++ SPR
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRD--QQSSSSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
Score = 38.9 bits (89), Expect = 0.006
Identities = 44/179 (24%), Positives = 70/179 (39%), Gaps = 32/179 (17%)
Query: 63 PKKMEKEPAARGTPGTGKERLKAGASPRSVPARK-------KAQTAPPLQP------PPP 109
P+ + P+ G+ R+K+ PR P+R KA +P + P P
Sbjct: 879 PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938
Query: 110 PPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAP 169
S P S++ C + S + L R + G ++ +V +P PP +
Sbjct: 939 SRVTSRTTPRRSRSVSPCSNVESRL--------LPRYSHSGSSSPDTKV-KPETPPRQSH 989
Query: 170 REPSSPLPKFEAQAPP------SAPPAPRAEAE--VRPKIPGSRE--AAENDEEEPGEA 218
SP PK +AQ PP S P P+ +++ + PGS A PGE+
Sbjct: 990 SGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048
Score = 30.4 bits (67), Expect = 2.3
Identities = 41/175 (23%), Positives = 62/175 (35%), Gaps = 15/175 (8%)
Query: 165 PSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVR 224
P+ +P + +++ A R + VR + SR A R
Sbjct: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR-SRSRSPARRSGRSRSRTPARRGR 657
Query: 225 EDRVTLADRG---PKERPRREGKPRKEKPRKEER-----PKKERPRKEERPRAAREPREA 276
T A RG + RR G+ R P + R P++ R R R R
Sbjct: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 277 LPQRWES-----REGGHRPWARDSR-DAEPRKKQAWVSPRRPDEEQRPGSRQKLR 325
+R S R+ R R SR ++ P K++ +S RR P S+ K R
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Score = 30.4 bits (67), Expect = 2.3
Identities = 60/305 (19%), Positives = 100/305 (32%), Gaps = 26/305 (8%)
Query: 36 SATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAA---RGTPGTGKERLKAGASPRSV 92
S TPR S S S V G S P++ + ++ + T + R ++ +SP
Sbjct: 694 SRTPRRGRSRS---RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMK 750
Query: 93 PARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLV----ALLGSAFQLCRDAV 148
+R ++ + L P L + C S + GS+ +
Sbjct: 751 KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 149 PGEAALQARVPEPWVP---PSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSR 205
P + + P P PS SSP PK ++ PP +A + P R
Sbjct: 811 PPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Query: 206 EAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEER----PKKERP 261
E+ + ++ + + R P R+ R P+ + + P++
Sbjct: 871 SCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH 930
Query: 262 RKEERPRAAREPREALPQRWES------REGGHRPWARDSRDAEPRKKQAWVSPRRPDEE 315
P +R P+R S E P S + P K V P P +
Sbjct: 931 SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTK---VKPETPPRQ 987
Query: 316 QRPGS 320
GS
Sbjct: 988 SHSGS 992
Score = 30.0 bits (66), Expect = 3.0
Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 14/105 (13%)
Query: 180 EAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERP 239
EA+ P PP P + RE++ + P + + ++DR R P
Sbjct: 159 EAKQPAPEPPKPYSLV---------RESSSSRSPTPKQKKKKK-KKDR---GRRSESSSP 205
Query: 240 RREGKPR-KEKPRKEERPKKERPRKEERPRAAREPREALPQRWES 283
RRE K K+K + E K+R + P++ R+ ++ +R S
Sbjct: 206 RRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRS 250
Score = 28.5 bits (62), Expect = 8.7
Identities = 33/158 (20%), Positives = 61/158 (38%), Gaps = 10/158 (6%)
Query: 173 SSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLAD 232
SSP PK ++Q PP + ++ + + + P R + + P + + + +
Sbjct: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR--SRSSSSPPPKQKSKTPSRQSHSSSS 839
Query: 233 RGPKER---PRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHR 289
PK + P R+G + ++ + R E P E + P R S G
Sbjct: 840 PHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP--ELKSRTPSR-HSCSGSSP 896
Query: 290 PWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAG 327
P + S PR+ + S +P + RQ+ +G
Sbjct: 897 PRVKSS--TPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 52.0 bits (123), Expect = 7e-07
Identities = 74/310 (23%), Positives = 123/310 (39%), Gaps = 43/310 (13%)
Query: 29 ETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGAS 88
+ ++ R S+T AD+G S E K+ME G P +ER +A ++
Sbjct: 866 QKKKKRHSSTGDSADAGPPAAGSARGE--------KEMEGVALKHG-PSLPQERKQAPST 916
Query: 89 PRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAV 148
R +++ P P PPP + P D + NK + LA AL A
Sbjct: 917 RRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANK-MPLAQKPALAPKPTSQTPPAS 975
Query: 149 PGEAALQARVPEPWV---------PPSSAPREPSSPLPKFEAQAPPSAPPAPR------- 192
P +++ P++ P P EPS + + PPS PP P
Sbjct: 976 P-----LSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDRRPPS-PPGPEERKGQKR 1029
Query: 193 -AEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKP- 250
E E + P S +E+P + T EA R+++ L R + + K +P
Sbjct: 1030 DEEEEATERKPASPPLPATQQEKPSQ-TPEAGRKEKPMLQSRHSLDGSKLTEKVETAQPL 1088
Query: 251 ------RKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARD-SRDAEPRKK 303
+K++ ++++ +EER + ARE ++A E+ +P + SR K
Sbjct: 1089 WITLALQKQKGFREQQATREER-KQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKS 1147
Query: 304 QAWVSPRRPD 313
A +RP+
Sbjct: 1148 TALPEEKRPE 1157
Score = 42.7 bits (99), Expect = 4e-04
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 17/163 (10%)
Query: 180 EAQAPP-SAPPAPRAEAEVRPKIPGSREAAEND---------EEEPGEATGEAVREDRVT 229
E Q PP A APR E + + PG +A + EEE +A E+R
Sbjct: 275 EGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRR 334
Query: 230 LADRGPKERPRR----EGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESRE 285
L + E RR EG+ +E R+EE + E++ + P EAL + E R
Sbjct: 335 LEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRR 394
Query: 286 GGHRPWARDSRDAEPRKKQAW---VSPRRPDEEQRPGSRQKLR 325
G + + + W +S D E+R +++L+
Sbjct: 395 GAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLK 437
Score = 34.3 bits (77), Expect = 0.16
Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 4/120 (3%)
Query: 212 EEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPK-KERPRKEERPRAA 270
+E P EA E + +L G ++ RRE + R+ +EER + + + + EER R
Sbjct: 277 QEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLE 336
Query: 271 REPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGKGR 330
+ R +R E EG A + + E + + W + + E + G+GR
Sbjct: 337 EDARLEERRRQEEEEG---RCAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGR 393
Score = 33.9 bits (76), Expect = 0.21
Identities = 41/165 (24%), Positives = 61/165 (36%), Gaps = 27/165 (16%)
Query: 181 AQAPPSAPPAPRAEAEVR-------PKIPGSREAAENDEEEPGEATGEAVREDRVTLADR 233
A A P A + R E E+ P +P R+ A + + E + V +A
Sbjct: 879 ADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSR----SVPVAHP 934
Query: 234 GPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWE-------SREG 286
GP + P +K + P ++P +P + P L + SR
Sbjct: 935 GPPPASSQTPAPEHDKAANK-MPLAQKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRA 993
Query: 287 GHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD 331
G RP D +EP K+ S RRP P R+ G+ RD
Sbjct: 994 G-RP---DPEPSEPSKEDQESSDRRPPSPPGPEERK----GQKRD 1030
Score = 30.0 bits (66), Expect = 3.0
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
Query: 193 AEAEVRPKIPGSREAAENDEEEPGEATGEA-VREDRVTLADRGPKERPRREGKPRKEKPR 251
+E E R + RE + + EA + + E R+ +R E RR+ +E
Sbjct: 217 SEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEG 276
Query: 252 KEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRR 311
+E + ER +EE+ R+ P +R E RE R A + R + QA RR
Sbjct: 277 QEPPLEAERAPREEQQRSLEAPGWEDAERRE-REERERLEAEEERRRLQAQAQA-EERRR 334
Query: 312 PDEEQRPGSRQKLRAGKGR 330
+E+ R R++ +GR
Sbjct: 335 LEEDARLEERRRQEEEEGR 353
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 52.0 bits (123), Expect = 7e-07
Identities = 74/313 (23%), Positives = 107/313 (34%), Gaps = 55/313 (17%)
Query: 10 ELDGGLGSC--QALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKME 67
E+ GGL C +AL E S+ P + D D Q+ V+ + +
Sbjct: 362 EIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQD--EDKQLIVELVVNKMAQALP 419
Query: 68 KEPAARGTPGTGKE-------RLKAGASPRSVPARKKAQTAPPLQPPPP----------P 110
++ +PG G L G PA AQ PP Q PP P
Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479
Query: 111 PALSEELPWGDLSLNKCLVLASLVALLGSAFQL---CRDAVPGEAALQARVPE------- 160
P P G L+ L GS + P + A QA P
Sbjct: 480 PLQQRPPPQGQQHLS------GLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
Query: 161 ------PWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEE 214
P PP++ P P+SP P+ +A PP A PK G+ + +
Sbjct: 534 RPVAGGPGAPPAARP--PASPSPQRQA-GPPQATRQTSVSGPAPPKASGAPPGGQQRQGP 590
Query: 215 PGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPR 274
P + G A + + A P+ P +PR P RPK P+ A++P
Sbjct: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPK---------PQLAQKPS 641
Query: 275 EALPQRWESREGG 287
+ +P + GG
Sbjct: 642 QDVPPPATAAAGG 654
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 52.0 bits (123), Expect = 7e-07
Identities = 74/313 (23%), Positives = 107/313 (34%), Gaps = 55/313 (17%)
Query: 10 ELDGGLGSC--QALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKME 67
E+ GGL C +AL E S+ P + D D Q+ V+ + +
Sbjct: 362 EIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQD--EDKQLIVELVVNKMAQALP 419
Query: 68 KEPAARGTPGTGKE-------RLKAGASPRSVPARKKAQTAPPLQPPPP----------P 110
++ +PG G L G PA AQ PP Q PP P
Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479
Query: 111 PALSEELPWGDLSLNKCLVLASLVALLGSAFQL---CRDAVPGEAALQARVPE------- 160
P P G L+ L GS + P + A QA P
Sbjct: 480 PLQQRPPPQGQQHLS------GLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
Query: 161 ------PWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEE 214
P PP++ P P+SP P+ +A PP A PK G+ + +
Sbjct: 534 RPVAGGPGAPPAARP--PASPSPQRQA-GPPQATRQTSVSGPAPPKASGAPPGGQQRQGP 590
Query: 215 PGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPR 274
P + G A + + A P+ P +PR P RPK P+ A++P
Sbjct: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPK---------PQLAQKPS 641
Query: 275 EALPQRWESREGG 287
+ +P + GG
Sbjct: 642 QDVPPPATAAAGG 654
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 51.2 bits (121), Expect = 1e-06
Identities = 59/263 (22%), Positives = 83/263 (31%), Gaps = 43/263 (16%)
Query: 30 TQEDRASATPR------LADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERL 83
T ++ AS TP+ + + + P + S T PK+ P T KE
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 279
Query: 84 KAGASPRSVPARKKAQTAP----PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGS 139
+ K A T P P P P P +E +
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------------------PT 320
Query: 140 AFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAEV 197
+ P E A + P P P AP P P P + P+ P PAP E
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 380
Query: 198 RP-----KIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRK 252
P P + ++A +EP T ++ + P +E P K
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-----APTTPKEPSPTTTKEPAPTTPKEPA 435
Query: 253 EERPKKERPR--KEERPRAAREP 273
PKK P KE P +EP
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEP 458
Score = 48.5 bits (114), Expect = 8e-06
Identities = 61/279 (21%), Positives = 86/279 (30%), Gaps = 36/279 (12%)
Query: 28 AETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGA 87
A T A TP+ + + T PKK P T KE
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE------ 457
Query: 88 SPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDA 147
P +K A T P P P + P K L + L + +
Sbjct: 458 -PAPTTTKKPAPTTPKEPAPTTPKETAPTTP-------KKLTPTTPEKLAPTTPEKPAPT 509
Query: 148 VPGEAA---------LQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAE 196
P E A P P P ++AP P P P + P+ P PAP E
Sbjct: 510 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 569
Query: 197 VRPKIPGS------REAAENDEEEPG--EATGEAVREDRVTLADRGPKERPRREG--KPR 246
P P +E A ++P E +E T D+ P+ P+
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629
Query: 247 KEKPRKEERPKKERPRKEERPRAAREPREALPQRWESRE 285
+ P + P P K P +EP P++ +E
Sbjct: 630 EPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKE 667
Score = 46.2 bits (108), Expect = 4e-05
Identities = 72/286 (25%), Positives = 93/286 (32%), Gaps = 66/286 (23%)
Query: 4 TTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRP 63
TT DG + A E S + +D A + LA P +GP++ T
Sbjct: 157 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT-- 212
Query: 64 KKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLS 123
KEP TP T KE A +P+ P ++AP P P P ++ P
Sbjct: 213 ---PKEP----TPTTPKE--PASTTPKE-PTPTTIKSAPTT-PKEPAPTTTKSAP----- 256
Query: 124 LNKCLVLASLVALLGSAFQLCRDAVPGEAA-LQARVPEPWVPPSSAPREPSSPLPKFEAQ 182
P E A + P P P AP P P
Sbjct: 257 -----------------------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293
Query: 183 AP-------PSAP--PAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADR 233
AP P+ P PAP E P P +E +EP T E A
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTP--KEPTPTTPKEPAPTTKEP--------APT 343
Query: 234 GPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQ 279
PKE P+K P + P P KE P +EP P+
Sbjct: 344 TPKE--PAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPK 386
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/298 (20%), Positives = 99/298 (33%), Gaps = 55/298 (18%)
Query: 30 TQEDRASATPRLADSG------SVPHDSQVAEGPSV----DTRPKKMEKEPAARGTPGTG 79
TQ ++ S +P++ + S+P +S ++ S+ +T + E + T G
Sbjct: 107 TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 166
Query: 80 KERLKAGASPRSVP---ARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVAL 136
KE+ + +S+ A+ A T+ L P P + +
Sbjct: 167 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-------------------- 206
Query: 137 LGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAE 196
G A ++ P P P S+ P+EP+ K P P A
Sbjct: 207 -GPALTTPKEPTP---------TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 197 VRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERP 256
PK P E P E +E T P P++ P ++P
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT-------TPKEPAPTTPKKP 309
Query: 257 KKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPR--KKQAWVSPRRP 312
P KE P +EP P+ E P ++ P KK A +P+ P
Sbjct: 310 APTTP-KEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 364
Score = 43.9 bits (102), Expect = 2e-04
Identities = 55/249 (22%), Positives = 75/249 (30%), Gaps = 30/249 (12%)
Query: 61 TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAP----PLQPPPPPPALSEE 116
T PK+ TP T KE P ++ A TAP P P P P +E
Sbjct: 312 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 371
Query: 117 -LPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE-----------AALQARVPEPWVP 164
P + SA ++ P + + P P P
Sbjct: 372 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431
Query: 165 PSSAPREPSSPLPKFEAQAPPSAP--PAP---RAEAEVRPKIPGSREAAENDEEEPGEAT 219
AP P P P + P+ P PAP + A PK P E P + T
Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491
Query: 220 GEAVREDRVTLADRGPKERPRR--EGKPRKEKPRKEERPKKERPR-------KEERPRAA 270
+ T ++ P P + P E P P+ KE P
Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 271 REPREALPQ 279
+EP P+
Sbjct: 552 KEPAPTTPK 560
Score = 42.7 bits (99), Expect = 4e-04
Identities = 67/286 (23%), Positives = 88/286 (30%), Gaps = 45/286 (15%)
Query: 30 TQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKK----MEKEPAARGTPGTGKERLKA 85
T E+ A TP+ A + + T PK+ KE A GT LK
Sbjct: 526 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585
Query: 86 GA------------------SPRSVPARKKAQTAP----PLQPPPPPPALSEE----LPW 119
A P S K A T P P P P P +E P
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645
Query: 120 GDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSP---L 176
G A + +L G + + P P P +AP P P
Sbjct: 646 GTAPTT-LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 704
Query: 177 PKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPK 236
PK A P PP +E P + + + P E+T E E + PK
Sbjct: 705 PKKPAPTTPETPPPTTSEVST----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 760
Query: 237 ERPRREGKPRKEKP--RKEERPKKERPRKEERP-RAAREPREALPQ 279
E G P + P K E + + ER R E A P+
Sbjct: 761 E----PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 802
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 51.2 bits (121), Expect = 1e-06
Identities = 59/263 (22%), Positives = 83/263 (31%), Gaps = 43/263 (16%)
Query: 30 TQEDRASATPR------LADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERL 83
T ++ AS TP+ + + + P + S T PK+ P T KE
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 320
Query: 84 KAGASPRSVPARKKAQTAP----PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGS 139
+ K A T P P P P P +E +
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------------------PT 361
Query: 140 AFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAEV 197
+ P E A + P P P AP P P P + P+ P PAP E
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 421
Query: 198 RP-----KIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRK 252
P P + ++A +EP T ++ + P +E P K
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-----APTTPKEPSPTTTKEPAPTTPKEPA 476
Query: 253 EERPKKERPR--KEERPRAAREP 273
PKK P KE P +EP
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEP 499
Score = 48.5 bits (114), Expect = 8e-06
Identities = 61/279 (21%), Positives = 86/279 (30%), Gaps = 36/279 (12%)
Query: 28 AETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGA 87
A T A TP+ + + T PKK P T KE
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE------ 498
Query: 88 SPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDA 147
P +K A T P P P + P K L + L + +
Sbjct: 499 -PAPTTTKKPAPTTPKEPAPTTPKETAPTTP-------KKLTPTTPEKLAPTTPEKPAPT 550
Query: 148 VPGEAA---------LQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAE 196
P E A P P P ++AP P P P + P+ P PAP E
Sbjct: 551 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 610
Query: 197 VRPKIPGS------REAAENDEEEPG--EATGEAVREDRVTLADRGPKERPRREG--KPR 246
P P +E A ++P E +E T D+ P+ P+
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670
Query: 247 KEKPRKEERPKKERPRKEERPRAAREPREALPQRWESRE 285
+ P + P P K P +EP P++ +E
Sbjct: 671 EPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKE 708
Score = 46.2 bits (108), Expect = 4e-05
Identities = 72/286 (25%), Positives = 93/286 (32%), Gaps = 66/286 (23%)
Query: 4 TTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRP 63
TT DG + A E S + +D A + LA P +GP++ T
Sbjct: 198 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT-- 253
Query: 64 KKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLS 123
KEP TP T KE A +P+ P ++AP P P P ++ P
Sbjct: 254 ---PKEP----TPTTPKE--PASTTPKE-PTPTTIKSAPTT-PKEPAPTTTKSAP----- 297
Query: 124 LNKCLVLASLVALLGSAFQLCRDAVPGEAA-LQARVPEPWVPPSSAPREPSSPLPKFEAQ 182
P E A + P P P AP P P
Sbjct: 298 -----------------------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334
Query: 183 AP-------PSAP--PAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADR 233
AP P+ P PAP E P P +E +EP T E A
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTP--KEPTPTTPKEPAPTTKEP--------APT 384
Query: 234 GPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQ 279
PKE P+K P + P P KE P +EP P+
Sbjct: 385 TPKE--PAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPK 427
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/298 (20%), Positives = 99/298 (33%), Gaps = 55/298 (18%)
Query: 30 TQEDRASATPRLADSG------SVPHDSQVAEGPSV----DTRPKKMEKEPAARGTPGTG 79
TQ ++ S +P++ + S+P +S ++ S+ +T + E + T G
Sbjct: 148 TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 207
Query: 80 KERLKAGASPRSVP---ARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVAL 136
KE+ + +S+ A+ A T+ L P P + +
Sbjct: 208 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-------------------- 247
Query: 137 LGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAE 196
G A ++ P P P S+ P+EP+ K P P A
Sbjct: 248 -GPALTTPKEPTP---------TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 197 VRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERP 256
PK P E P E +E T P P++ P ++P
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT-------TPKEPAPTTPKKP 350
Query: 257 KKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPR--KKQAWVSPRRP 312
P KE P +EP P+ E P ++ P KK A +P+ P
Sbjct: 351 APTTP-KEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 405
Score = 43.9 bits (102), Expect = 2e-04
Identities = 55/249 (22%), Positives = 75/249 (30%), Gaps = 30/249 (12%)
Query: 61 TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAP----PLQPPPPPPALSEE 116
T PK+ TP T KE P ++ A TAP P P P P +E
Sbjct: 353 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 412
Query: 117 -LPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE-----------AALQARVPEPWVP 164
P + SA ++ P + + P P P
Sbjct: 413 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472
Query: 165 PSSAPREPSSPLPKFEAQAPPSAP--PAP---RAEAEVRPKIPGSREAAENDEEEPGEAT 219
AP P P P + P+ P PAP + A PK P E P + T
Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532
Query: 220 GEAVREDRVTLADRGPKERPRR--EGKPRKEKPRKEERPKKERPR-------KEERPRAA 270
+ T ++ P P + P E P P+ KE P
Sbjct: 533 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 271 REPREALPQ 279
+EP P+
Sbjct: 593 KEPAPTTPK 601
Score = 42.7 bits (99), Expect = 4e-04
Identities = 67/286 (23%), Positives = 88/286 (30%), Gaps = 45/286 (15%)
Query: 30 TQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKK----MEKEPAARGTPGTGKERLKA 85
T E+ A TP+ A + + T PK+ KE A GT LK
Sbjct: 567 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626
Query: 86 GA------------------SPRSVPARKKAQTAP----PLQPPPPPPALSEE----LPW 119
A P S K A T P P P P P +E P
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686
Query: 120 GDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSP---L 176
G A + +L G + + P P P +AP P P
Sbjct: 687 GTAPTT-LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 745
Query: 177 PKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPK 236
PK A P PP +E P + + + P E+T E E + PK
Sbjct: 746 PKKPAPTTPETPPPTTSEVST----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 801
Query: 237 ERPRREGKPRKEKP--RKEERPKKERPRKEERP-RAAREPREALPQ 279
E G P + P K E + + ER R E A P+
Sbjct: 802 E----PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 843
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 51.2 bits (121), Expect = 1e-06
Identities = 59/263 (22%), Positives = 83/263 (31%), Gaps = 43/263 (16%)
Query: 30 TQEDRASATPR------LADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERL 83
T ++ AS TP+ + + + P + S T PK+ P T KE
Sbjct: 313 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 372
Query: 84 KAGASPRSVPARKKAQTAP----PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGS 139
+ K A T P P P P P +E +
Sbjct: 373 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------------------PT 413
Query: 140 AFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAEV 197
+ P E A + P P P AP P P P + P+ P PAP E
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 473
Query: 198 RP-----KIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRK 252
P P + ++A +EP T ++ + P +E P K
Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-----APTTPKEPSPTTTKEPAPTTPKEPA 528
Query: 253 EERPKKERPR--KEERPRAAREP 273
PKK P KE P +EP
Sbjct: 529 PTTPKKPAPTTPKEPAPTTPKEP 551
Score = 48.5 bits (114), Expect = 8e-06
Identities = 61/279 (21%), Positives = 86/279 (30%), Gaps = 36/279 (12%)
Query: 28 AETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGA 87
A T A TP+ + + T PKK P T KE
Sbjct: 497 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE------ 550
Query: 88 SPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDA 147
P +K A T P P P + P K L + L + +
Sbjct: 551 -PAPTTTKKPAPTTPKEPAPTTPKETAPTTP-------KKLTPTTPEKLAPTTPEKPAPT 602
Query: 148 VPGEAA---------LQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAE 196
P E A P P P ++AP P P P + P+ P PAP E
Sbjct: 603 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 662
Query: 197 VRPKIPGS------REAAENDEEEPG--EATGEAVREDRVTLADRGPKERPRREG--KPR 246
P P +E A ++P E +E T D+ P+ P+
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722
Query: 247 KEKPRKEERPKKERPRKEERPRAAREPREALPQRWESRE 285
+ P + P P K P +EP P++ +E
Sbjct: 723 EPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKE 760
Score = 46.2 bits (108), Expect = 4e-05
Identities = 72/286 (25%), Positives = 93/286 (32%), Gaps = 66/286 (23%)
Query: 4 TTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRP 63
TT DG + A E S + +D A + LA P +GP++ T
Sbjct: 250 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT-- 305
Query: 64 KKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLS 123
KEP TP T KE A +P+ P ++AP P P P ++ P
Sbjct: 306 ---PKEP----TPTTPKE--PASTTPKE-PTPTTIKSAPTT-PKEPAPTTTKSAP----- 349
Query: 124 LNKCLVLASLVALLGSAFQLCRDAVPGEAA-LQARVPEPWVPPSSAPREPSSPLPKFEAQ 182
P E A + P P P AP P P
Sbjct: 350 -----------------------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 386
Query: 183 AP-------PSAP--PAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADR 233
AP P+ P PAP E P P +E +EP T E A
Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKEPAPTTP--KEPTPTTPKEPAPTTKEP--------APT 436
Query: 234 GPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQ 279
PKE P+K P + P P KE P +EP P+
Sbjct: 437 TPKE--PAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPK 479
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/298 (20%), Positives = 99/298 (33%), Gaps = 55/298 (18%)
Query: 30 TQEDRASATPRLADSG------SVPHDSQVAEGPSV----DTRPKKMEKEPAARGTPGTG 79
TQ ++ S +P++ + S+P +S ++ S+ +T + E + T G
Sbjct: 200 TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 259
Query: 80 KERLKAGASPRSVP---ARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVAL 136
KE+ + +S+ A+ A T+ L P P + +
Sbjct: 260 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-------------------- 299
Query: 137 LGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAE 196
G A ++ P P P S+ P+EP+ K P P A
Sbjct: 300 -GPALTTPKEPTP---------TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 197 VRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERP 256
PK P E P E +E T P P++ P ++P
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT-------TPKEPAPTTPKKP 402
Query: 257 KKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPR--KKQAWVSPRRP 312
P KE P +EP P+ E P ++ P KK A +P+ P
Sbjct: 403 APTTP-KEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 457
Score = 43.9 bits (102), Expect = 2e-04
Identities = 55/249 (22%), Positives = 75/249 (30%), Gaps = 30/249 (12%)
Query: 61 TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAP----PLQPPPPPPALSEE 116
T PK+ TP T KE P ++ A TAP P P P P +E
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 464
Query: 117 -LPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE-----------AALQARVPEPWVP 164
P + SA ++ P + + P P P
Sbjct: 465 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524
Query: 165 PSSAPREPSSPLPKFEAQAPPSAP--PAP---RAEAEVRPKIPGSREAAENDEEEPGEAT 219
AP P P P + P+ P PAP + A PK P E P + T
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584
Query: 220 GEAVREDRVTLADRGPKERPRR--EGKPRKEKPRKEERPKKERPR-------KEERPRAA 270
+ T ++ P P + P E P P+ KE P
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Query: 271 REPREALPQ 279
+EP P+
Sbjct: 645 KEPAPTTPK 653
Score = 42.7 bits (99), Expect = 4e-04
Identities = 67/286 (23%), Positives = 88/286 (30%), Gaps = 45/286 (15%)
Query: 30 TQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKK----MEKEPAARGTPGTGKERLKA 85
T E+ A TP+ A + + T PK+ KE A GT LK
Sbjct: 619 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 678
Query: 86 GA------------------SPRSVPARKKAQTAP----PLQPPPPPPALSEE----LPW 119
A P S K A T P P P P P +E P
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738
Query: 120 GDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSP---L 176
G A + +L G + + P P P +AP P P
Sbjct: 739 GTAPTT-LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 797
Query: 177 PKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPK 236
PK A P PP +E P + + + P E+T E E + PK
Sbjct: 798 PKKPAPTTPETPPPTTSEVST----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 853
Query: 237 ERPRREGKPRKEKP--RKEERPKKERPRKEERP-RAAREPREALPQ 279
E G P + P K E + + ER R E A P+
Sbjct: 854 E----PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 895
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 51.2 bits (121), Expect = 1e-06
Identities = 59/263 (22%), Positives = 83/263 (31%), Gaps = 43/263 (16%)
Query: 30 TQEDRASATPR------LADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERL 83
T ++ AS TP+ + + + P + S T PK+ P T KE
Sbjct: 354 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 413
Query: 84 KAGASPRSVPARKKAQTAP----PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGS 139
+ K A T P P P P P +E +
Sbjct: 414 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------------------PT 454
Query: 140 AFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAEV 197
+ P E A + P P P AP P P P + P+ P PAP E
Sbjct: 455 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 514
Query: 198 RP-----KIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRK 252
P P + ++A +EP T ++ + P +E P K
Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-----APTTPKEPSPTTTKEPAPTTPKEPA 569
Query: 253 EERPKKERPR--KEERPRAAREP 273
PKK P KE P +EP
Sbjct: 570 PTTPKKPAPTTPKEPAPTTPKEP 592
Score = 48.5 bits (114), Expect = 8e-06
Identities = 61/279 (21%), Positives = 86/279 (30%), Gaps = 36/279 (12%)
Query: 28 AETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGA 87
A T A TP+ + + T PKK P T KE
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE------ 591
Query: 88 SPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDA 147
P +K A T P P P + P K L + L + +
Sbjct: 592 -PAPTTTKKPAPTTPKEPAPTTPKETAPTTP-------KKLTPTTPEKLAPTTPEKPAPT 643
Query: 148 VPGEAA---------LQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAP--PAPRAEAE 196
P E A P P P ++AP P P P + P+ P PAP E
Sbjct: 644 TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 703
Query: 197 VRPKIPGS------REAAENDEEEPG--EATGEAVREDRVTLADRGPKERPRREG--KPR 246
P P +E A ++P E +E T D+ P+ P+
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763
Query: 247 KEKPRKEERPKKERPRKEERPRAAREPREALPQRWESRE 285
+ P + P P K P +EP P++ +E
Sbjct: 764 EPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKE 801
Score = 46.2 bits (108), Expect = 4e-05
Identities = 72/286 (25%), Positives = 93/286 (32%), Gaps = 66/286 (23%)
Query: 4 TTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRP 63
TT DG + A E S + +D A + LA P +GP++ T
Sbjct: 291 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT-- 346
Query: 64 KKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLS 123
KEP TP T KE A +P+ P ++AP P P P ++ P
Sbjct: 347 ---PKEP----TPTTPKE--PASTTPKE-PTPTTIKSAPTT-PKEPAPTTTKSAP----- 390
Query: 124 LNKCLVLASLVALLGSAFQLCRDAVPGEAA-LQARVPEPWVPPSSAPREPSSPLPKFEAQ 182
P E A + P P P AP P P
Sbjct: 391 -----------------------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 427
Query: 183 AP-------PSAP--PAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADR 233
AP P+ P PAP E P P +E +EP T E A
Sbjct: 428 APTTPKEPAPTTPKKPAPTTPKEPAPTTP--KEPTPTTPKEPAPTTKEP--------APT 477
Query: 234 GPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQ 279
PKE P+K P + P P KE P +EP P+
Sbjct: 478 TPKE--PAPTAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPK 520
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/298 (20%), Positives = 99/298 (33%), Gaps = 55/298 (18%)
Query: 30 TQEDRASATPRLADSG------SVPHDSQVAEGPSV----DTRPKKMEKEPAARGTPGTG 79
TQ ++ S +P++ + S+P +S ++ S+ +T + E + T G
Sbjct: 241 TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 300
Query: 80 KERLKAGASPRSVP---ARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVAL 136
KE+ + +S+ A+ A T+ L P P + +
Sbjct: 301 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-------------------- 340
Query: 137 LGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAE 196
G A ++ P P P S+ P+EP+ K P P A
Sbjct: 341 -GPALTTPKEPTP---------TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 197 VRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERP 256
PK P E P E +E T P P++ P ++P
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT-------TPKEPAPTTPKKP 443
Query: 257 KKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPR--KKQAWVSPRRP 312
P KE P +EP P+ E P ++ P KK A +P+ P
Sbjct: 444 APTTP-KEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 498
Score = 43.9 bits (102), Expect = 2e-04
Identities = 55/249 (22%), Positives = 75/249 (30%), Gaps = 30/249 (12%)
Query: 61 TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAP----PLQPPPPPPALSEE 116
T PK+ TP T KE P ++ A TAP P P P P +E
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 505
Query: 117 -LPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE-----------AALQARVPEPWVP 164
P + SA ++ P + + P P P
Sbjct: 506 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565
Query: 165 PSSAPREPSSPLPKFEAQAPPSAP--PAP---RAEAEVRPKIPGSREAAENDEEEPGEAT 219
AP P P P + P+ P PAP + A PK P E P + T
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625
Query: 220 GEAVREDRVTLADRGPKERPRR--EGKPRKEKPRKEERPKKERPR-------KEERPRAA 270
+ T ++ P P + P E P P+ KE P
Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685
Query: 271 REPREALPQ 279
+EP P+
Sbjct: 686 KEPAPTTPK 694
Score = 42.7 bits (99), Expect = 4e-04
Identities = 67/286 (23%), Positives = 88/286 (30%), Gaps = 45/286 (15%)
Query: 30 TQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKK----MEKEPAARGTPGTGKERLKA 85
T E+ A TP+ A + + T PK+ KE A GT LK
Sbjct: 660 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719
Query: 86 GA------------------SPRSVPARKKAQTAP----PLQPPPPPPALSEE----LPW 119
A P S K A T P P P P P +E P
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779
Query: 120 GDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSP---L 176
G A + +L G + + P P P +AP P P
Sbjct: 780 GTAPTT-LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 838
Query: 177 PKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPK 236
PK A P PP +E P + + + P E+T E E + PK
Sbjct: 839 PKKPAPTTPETPPPTTSEVST----PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 894
Query: 237 ERPRREGKPRKEKP--RKEERPKKERPRKEERP-RAAREPREALPQ 279
E G P + P K E + + ER R E A P+
Sbjct: 895 E----PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 936
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 50.8 bits (120), Expect = 2e-06
Identities = 74/294 (25%), Positives = 122/294 (41%), Gaps = 38/294 (12%)
Query: 51 SQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGA-SPRSVPARKKAQTAPPLQPPPP 109
S V E + K KE A TP K +K A SP + +KA+T P
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAK--TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAK 767
Query: 110 PPALSEELPWGDLSLNKCL--VLASLVALLGSAFQLCRDA------VPGEAALQARVPEP 161
PA E D K V + + + L DA +P + +++ V E
Sbjct: 768 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE 827
Query: 162 WVP--------PSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEE 213
P P A E + PK E + AP+ EA +PK+ +E A E
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAP-KPKVEEKKEPAV---E 883
Query: 214 EPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKK--ERPRKEERPRAAR 271
+P E+ EA +E+ D+ P +E P K + +++ +PK+ E +KE A+
Sbjct: 884 KPKESKVEAKKEEA---EDKKKVPTPEKEA-PAKVEVKEDAKPKEKTEVAKKEPDDAKAK 939
Query: 272 EP------REALPQRWESR-EGGHRPWARDSRDAEPRKKQAWVS--PRRPDEEQ 316
EP +EA P++ +++ E +P + +A+ ++ +S P +P E+
Sbjct: 940 EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Score = 47.0 bits (110), Expect = 2e-05
Identities = 64/272 (23%), Positives = 108/272 (39%), Gaps = 38/272 (13%)
Query: 62 RPKKMEKEPAARGTPGTGKERLKAGA-SPRSVPARKKAQTAPPLQPPPPPPALSEELPWG 120
+ K EKE A +P K +KA A SP + KA+ P + P + EE
Sbjct: 651 KAKSPEKEEAK--SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP---VKEEAKSP 705
Query: 121 DLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSP--LPK 178
+ + S V + + + V EA + P + +P + SP
Sbjct: 706 EKA-------KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 179 FEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKER 238
+ ++P + PA K P ++ +E + E ++ED A KE
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED----AKAPEKEI 814
Query: 239 PRRE--GKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSR 296
P++E P KE+ + +E KE P+K E +A P+ E + +DS+
Sbjct: 815 PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT------EEK--------KDSK 860
Query: 297 DAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGK 328
E KK+A P+ EE++ + +K + K
Sbjct: 861 KEEAPKKEA---PKPKVEEKKEPAVEKPKESK 889
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 19/187 (10%)
Query: 145 RDAVPGEAALQARVPEPWVPPSSAPREPSSPLP-----KFEAQAPPSAPPAPRAEAEV-- 197
+ V EA A P + +P E SP K EA++PP A + EA+
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA 576
Query: 198 ------RPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPR 251
+ K P EA E + E V+E+ + A+ + + + P
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE 636
Query: 252 KEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRR 311
K + P KE + E+ ++ + P++ +S P +++ E K +
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS------PVKAEAKSPEKAKSPVKAEAKS 690
Query: 312 PDEEQRP 318
P++ + P
Sbjct: 691 PEKAKSP 697
Score = 40.0 bits (92), Expect = 0.003
Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 11/162 (6%)
Query: 166 SSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVRE 225
+S +E SP+ K EA++P A + EA+ ++ S E A++ +E ++ EA
Sbjct: 510 ASPEKEAKSPV-KEEAKSPAEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPPEAKSP 567
Query: 226 DRVTLADRGPKERPRREGKPRKEK---------PRKEERPKKERPRKEERPRAAREPREA 276
++ + P + P KE+ P K + P KE + ++ +
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK 627
Query: 277 LPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRP 318
P +S E P +++ E K + P++ + P
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669
Score = 32.7 bits (73), Expect = 0.46
Identities = 32/128 (25%), Positives = 49/128 (38%), Gaps = 9/128 (7%)
Query: 196 EVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEK-PRKEE 254
E K P + EAA ++E EA ++ + P P K K P KEE
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 255 R---PKKERPRKEERPRAAREPREA-LPQRWESREGGHRPWARDSRDAEPRKKQAWVSPR 310
P+ + P KEE A+ P E P++ +S +++ E K +
Sbjct: 558 AKSPPEAKSPEKEE----AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613
Query: 311 RPDEEQRP 318
P E + P
Sbjct: 614 SPAEAKSP 621
Score = 31.6 bits (70), Expect = 1.0
Identities = 31/142 (21%), Positives = 58/142 (40%), Gaps = 9/142 (6%)
Query: 189 PAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKE 248
P P + E PKIP + EE + ++ +E V + ++ + + E +E
Sbjct: 417 PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKET-VIVEEQTEETQVTEEVTEEEE 475
Query: 249 KPRKEERPKKERPRKEERPRAARE-----PREALPQRWESREGGHRPWARDSRDAEPRKK 303
K KEE K+E +EE E P E + + + A+ +A+ +K
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK 535
Query: 304 QAWVSP---RRPDEEQRPGSRQ 322
+ SP + P++ + P +
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEE 557
Score = 29.6 bits (65), Expect = 3.9
Identities = 32/134 (23%), Positives = 50/134 (37%), Gaps = 10/134 (7%)
Query: 194 EAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRRE-GKPRKE--KP 250
E +V ++ E +EE E GE E+ + K P E P KE P
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGE---EEEAEGGEEETKSPPAEEAASPEKEAKSP 519
Query: 251 RKEERPKKERPRKEERPRAAREPREALPQRWES--REGGHRPWARDSRDAEPRKKQAWVS 308
KEE + E+ A P++ +S +E P S + E K A V
Sbjct: 520 VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV- 578
Query: 309 PRRPDEEQRPGSRQ 322
+ P++ + P +
Sbjct: 579 -KSPEKAKSPAKEE 591
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 50.4 bits (119), Expect = 2e-06
Identities = 35/137 (25%), Positives = 69/137 (50%), Gaps = 9/137 (6%)
Query: 192 RAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPR 251
R E E + K +E + +E+ + R +R +R +ER ++ + RK K R
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Query: 252 KEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRR 311
++++ +KER R++ER + R+ ++ ++ E RE + R+ + RKK+ RR
Sbjct: 139 RKKKRRKERKREKERGKRERKRKK---RKKEERE------KKRERNRKERKKERERKERR 189
Query: 312 PDEEQRPGSRQKLRAGK 328
+++R R+K + K
Sbjct: 190 ERKKERKKERRKKKERK 206
Score = 47.8 bits (112), Expect = 1e-05
Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 192 RAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKER-------PRREGK 244
R + R + G +E + + E G+ +E +R KER +RE K
Sbjct: 48 REREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107
Query: 245 PRKEKPRKEERPKKERPR----KEERPRAAREPREALPQRWESREGGHRPWARDSRDAEP 300
R + RK+++ +KER R + ER R R ++ +R +E G R R R E
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Query: 301 R-KKQAWVSPRRPDEEQRPGSRQKLRAGK 328
R KK+ R E +R R++ + K
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERK 196
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 3/114 (2%)
Query: 217 EATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREA 276
E+ + R +R KER R GK K+K +K ER K+ +++ER + +E RE
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE- 91
Query: 277 LPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGKGR 330
+ R+ + R R RKK+ R + +QR ++K R K R
Sbjct: 92 --KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
Query: 196 EVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEER 255
E R K R+ + E E ++ +R K+R R+ K R++K R++ER
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
Query: 256 PKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEE 315
+++ K ER R R+ E +R +R+ R R+ ++ RKK+ R+ E
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRK--ERKKERERKERRERKKERKKERRKKKER 205
Query: 316 QR 317
++
Sbjct: 206 KK 207
Score = 42.7 bits (99), Expect = 4e-04
Identities = 36/146 (24%), Positives = 72/146 (49%), Gaps = 7/146 (4%)
Query: 189 PAPRAEAEVRPKIPGSREAAEND-EEEPGEATGEAVREDRVTLADRGPKERPRREGKPRK 247
P + E+E R K RE + + E+E G+ ++ R +ER R+E + ++
Sbjct: 28 PCTQRESE-RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 248 EKPRKEERPKK--ERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQA 305
++ R++ER K+ E+ ++E + R RE ++ ++ RE R R+ + + RKK+
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR---RERKRKKRRKKKR 143
Query: 306 WVSPRRPDEEQRPGSRQKLRAGKGRD 331
+R E + ++K R + R+
Sbjct: 144 RKERKREKERGKRERKRKKRKKEERE 169
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 10/127 (7%)
Query: 194 EAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKE 253
E R K RE + E + RE R R K + RR+ K RKE+ R++
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERE-RENKQRRERKRKKRRKKKRRKERKREK 151
Query: 254 ERPKKE-----RPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVS 308
ER K+E R +KEER + R+ +R + RE R + R E RKK+
Sbjct: 152 ERGKRERKRKKR-KKEEREKKRERNRK---ERKKERERKERRERKKERKKERRKKKERKK 207
Query: 309 PRRPDEE 315
R+ D +
Sbjct: 208 DRKTDRQ 214
Score = 39.3 bits (90), Expect = 0.005
Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 205 REAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKP-----RKEKPRKEERPKKE 259
RE + E + + + R++R +RG +ER R++ K ++E+ RKE + ++E
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERE 184
Query: 260 RPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAW 306
R + ER + ++ R +R + R+ + DS+ P ++ A+
Sbjct: 185 RKERRERKKERKKERRKKKERKKDRKTDRQ---TDSQVFRPLRESAF 228
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 50.4 bits (119), Expect = 2e-06
Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 15/172 (8%)
Query: 158 VPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGE 217
VPE P P S +P Q P PA E V K +R + EP +
Sbjct: 532 VPEDGSPEKRCPGGVLSCIPDNNQQ--PKGIPA--CEQNVSRK--DTRSEQDKCNREPSK 585
Query: 218 ATGEAVREDRVTLADRGPKERPRREGKPRKE--KPRKEERPKKERPRKEERP-RAAREPR 274
G A + LADR +ER R +E +PRKE RP K+ K++ P R + P
Sbjct: 586 GRGRATGDG---LADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPD 642
Query: 275 EALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRA 326
+R S++ R +R+ R + RK RR E R S + R+
Sbjct: 643 HTRSRRSHSKDRHRRERSRERRGSASRKHS---RHRRRSERSRSRSPSRHRS 691
Score = 34.7 bits (78), Expect = 0.12
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 230 LADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALP--QRWESREGG 287
L+D K+R K ++ + ++EE+ ++E+ EER RA ++ L +R RE
Sbjct: 263 LSDASIKKRQLERQKLQELEQQREEQKRREK-EAEERQRAEERKQKELEELERERKREEK 321
Query: 288 HRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGK 328
R + RD E R+ Q + + +E+++ + KL K
Sbjct: 322 LRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERK 362
Score = 29.6 bits (65), Expect = 3.9
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 192 RAEAEVRPKIPGSREAAEN-DEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKP 250
R E + R K R+ AE ++E E E RE+++ ++ ++R R + + EK
Sbjct: 285 REEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKL 344
Query: 251 RKEERPK-KERPRKEER 266
+ EE+ + +E+ + EER
Sbjct: 345 QAEEQKQLQEKIKLEER 361
>gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]
Length = 1133
Score = 50.1 bits (118), Expect = 3e-06
Identities = 75/279 (26%), Positives = 102/279 (36%), Gaps = 39/279 (13%)
Query: 34 RASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVP 93
R P D+ P + Q+ P P+A T ERL+ G P S
Sbjct: 871 RGPLPPSADDNLKTPSERQLT--------PLPPSAPPSADDNIKTPAERLR-GPLPPSAD 921
Query: 94 ARKKAQTAPPLQPPPP--PPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE 151
K + L P PP PP+ + + L L ++ L P E
Sbjct: 922 DNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNL----------KTPSE 971
Query: 152 AALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSA------PPAPRAEAEV-RPKIPGS 204
L P P P SA +P + PPSA PP EAE +P+ P
Sbjct: 972 RQL---TPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPPLATQEAEAEKPRKPKR 1028
Query: 205 REAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKE 264
+ AAE E P E V + + R PK R + +P +P++ E RK
Sbjct: 1029 QRAAEM--EPPPEPKRRRVGDVEPS---RKPKRRRAADVEPSSPEPKRRRVGDVEPSRKP 1083
Query: 265 ERPRAAR-EPREALPQRWE--SREGGHRPWARDSRDAEP 300
+R RAA EP P+R E +P R + D EP
Sbjct: 1084 KRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEP 1122
Score = 36.2 bits (82), Expect = 0.042
Identities = 66/274 (24%), Positives = 96/274 (35%), Gaps = 54/274 (19%)
Query: 57 PSVDTRPKKMEKEPA----ARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPP--P 110
PSV + P + P +R P ERL+ G P S K + L P PP P
Sbjct: 840 PSVSSLPFHPQLHPQQMIISRHLPSVCGERLR-GPLPPSADDNLKTPSERQLTPLPPSAP 898
Query: 111 PALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPR 170
P+ + + L L ++ L P E L P P P SA
Sbjct: 899 PSADDNIKTPAERLRGPLPPSADDNL----------KTPSERQL---TPLPPSAPPSADD 945
Query: 171 EPSSPLPKFEAQAPPSAPPAPR--AEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRV 228
+P + PPSA + +E ++ P P + +A+++ + P E
Sbjct: 946 NIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERL--------- 996
Query: 229 TLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGH 288
RGP P K P + + E+PRK QR E
Sbjct: 997 ----RGPL--PPSADDNLKTPPLATQEAEAEKPRK------------PKRQRAAEMEPPP 1038
Query: 289 RPWARDSRDAEP-----RKKQAWVSPRRPDEEQR 317
P R D EP R++ A V P P+ ++R
Sbjct: 1039 EPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRR 1072
>gi|157074225 nuclear pore complex interacting protein-like 3 [Homo
sapiens]
Length = 678
Score = 50.1 bits (118), Expect = 3e-06
Identities = 75/279 (26%), Positives = 102/279 (36%), Gaps = 39/279 (13%)
Query: 34 RASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVP 93
R P D+ P + Q+ P P+A T ERL+ G P S
Sbjct: 416 RGPLPPSADDNLKTPSERQLT--------PLPPSAPPSADDNIKTPAERLR-GPLPPSAD 466
Query: 94 ARKKAQTAPPLQPPPP--PPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE 151
K + L P PP PP+ + + L L ++ L P E
Sbjct: 467 DNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNL----------KTPSE 516
Query: 152 AALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSA------PPAPRAEAEV-RPKIPGS 204
L P P P SA +P + PPSA PP EAE +P+ P
Sbjct: 517 RQL---TPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPPLATQEAEAEKPRKPKR 573
Query: 205 REAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKE 264
+ AAE E P E V + + R PK R + +P +P++ E RK
Sbjct: 574 QRAAEM--EPPPEPKRRRVGDVEPS---RKPKRRRAADVEPSSPEPKRRRVGDVEPSRKP 628
Query: 265 ERPRAAR-EPREALPQRWE--SREGGHRPWARDSRDAEP 300
+R RAA EP P+R E +P R + D EP
Sbjct: 629 KRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEP 667
Score = 34.3 bits (77), Expect = 0.16
Identities = 62/257 (24%), Positives = 90/257 (35%), Gaps = 50/257 (19%)
Query: 70 PAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPP--PPALSEELPWGDLSLNKC 127
P+A T ERL+ G P S K + L P PP PP+ + + L
Sbjct: 402 PSADDNIKTPAERLR-GPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGP 460
Query: 128 LVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSA 187
L ++ L P E L P P P SA +P + PPSA
Sbjct: 461 LPPSADDNL----------KTPSERQL---TPLPPSAPPSADDNIKTPAERLRGPLPPSA 507
Query: 188 PPAPR--AEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKP 245
+ +E ++ P P + +A+++ + P E RGP P
Sbjct: 508 DDNLKTPSERQLTPLPPSAPPSADDNIKTPAERL-------------RGPL--PPSADDN 552
Query: 246 RKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEP----- 300
K P + + E+PRK QR E P R D EP
Sbjct: 553 LKTPPLATQEAEAEKPRK------------PKRQRAAEMEPPPEPKRRRVGDVEPSRKPK 600
Query: 301 RKKQAWVSPRRPDEEQR 317
R++ A V P P+ ++R
Sbjct: 601 RRRAADVEPSSPEPKRR 617
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/179 (26%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 159 PEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPR-----AEAEVRPKIP----GSREAAE 209
PEP P P P P+ PP PPA + + + P+ P G R A
Sbjct: 23 PEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPP 82
Query: 210 NDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEK-PRKEERPKKERPRKE-ERP 267
+E EA + D P PRR +P P + P K+ +K ER
Sbjct: 83 QEESPSSEAKSRGPTPPAMGPRDARP---PRRSSQPSPTAVPASDSPPTKQEVKKAGERH 139
Query: 268 RAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRA 326
+ A+E RE +R + W A+ +++ RR EEQR + Q+ A
Sbjct: 140 KLAKERRE---ERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAA 195
Score = 50.1 bits (118), Expect = 3e-06
Identities = 72/287 (25%), Positives = 107/287 (37%), Gaps = 41/287 (14%)
Query: 64 KKMEKEPAARGTPGTGKE---RLKAGASPRSVPARKKAQTAPP------LQPPPPPPALS 114
+ + P AR + T E + KA S S + A P L P PP P +
Sbjct: 441 QSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGT 500
Query: 115 EELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSS 174
P G + + + A Q R A + + P P PS P P
Sbjct: 501 TASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQK 560
Query: 175 PLPKFE------------AQAPPSAPPAPRA-----EAEVRPKIPGSREAAENDEEEPGE 217
P E A APP P P A E R R+A E E E E
Sbjct: 561 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQE 620
Query: 218 ATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREAL 277
+A R+ R+ +E+ RE + R E R+ E ++E E+ +A +E +E L
Sbjct: 621 RRLQAERDKRMR------EEQLAREAEARAE--REAEARRREEQEAREKAQAEQEEQERL 672
Query: 278 PQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKL 324
++ E E AR +AE R++ + E++R R++L
Sbjct: 673 QKQKEEAE------ARSREEAE-RQRLEREKHFQQQEQERQERRKRL 712
Score = 47.8 bits (112), Expect = 1e-05
Identities = 41/175 (23%), Positives = 67/175 (38%), Gaps = 30/175 (17%)
Query: 164 PPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEE---EPGEATG 220
PP+ R P P P E P PP + P P + + A + ++ EP +G
Sbjct: 14 PPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSG 73
Query: 221 EAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREP------- 273
+ GP+ P +E P E + P PR PR + +P
Sbjct: 74 QV-----------GPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPA 122
Query: 274 REALPQRWESREGGHR-PWARDSRDAEPR----KKQAWVSPRRPDEEQRPGSRQK 323
++ P + E ++ G R A++ R+ + KK W+ EE+ R+K
Sbjct: 123 SDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLE----KEEKAKALREK 173
Score = 41.2 bits (95), Expect = 0.001
Identities = 50/214 (23%), Positives = 79/214 (36%), Gaps = 33/214 (15%)
Query: 80 KERLKAGASP----RSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVA 135
+ L AGA P R+ P + + P PPPP AL + P K +
Sbjct: 6 RAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSK--- 62
Query: 136 LLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPA----- 190
+ L+ P V P AP + SP + +++ P PPA
Sbjct: 63 ---------------QLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGP--TPPAMGPRD 105
Query: 191 ---PRAEAEVRP-KIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPR 246
PR ++ P +P S E + + +E R A ++ K
Sbjct: 106 ARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEE 165
Query: 247 KEKPRKEERPKKERPRKEERPRAAREPREALPQR 280
K K +E++ ++ R R EE+ A + R AL +R
Sbjct: 166 KAKALREKQLQERRRRLEEQRLKAEQRRAALEER 199
Score = 36.6 bits (83), Expect = 0.032
Identities = 54/226 (23%), Positives = 85/226 (37%), Gaps = 28/226 (12%)
Query: 50 DSQVAEGPSVDTRPKKM---EKEPAARGTPGTGKERLKAGASPRSV--PARKKAQTAPPL 104
+S A GP ++ K+ EKE AA +P A P+ PA A
Sbjct: 516 ESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLT 575
Query: 105 QPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVP 164
PP P P ++ P + + L+A + R+ E LQA + +
Sbjct: 576 SPPAPAPPVTPSKPMAGTTDRE--EATRLLAEKRRQAREQREREEQERRLQAE-RDKRMR 632
Query: 165 PSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVR 224
RE EA+A A R E E R K +E E +++ EA +
Sbjct: 633 EEQLAREA-------EARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSRE 685
Query: 225 EDRVTLADRGPKERPRREGKPRKEKPRKEERPKK-----ERPRKEE 265
E ++R RE ++++ ++ER K+ +R RK E
Sbjct: 686 E--------AERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSE 723
Score = 31.2 bits (69), Expect = 1.3
Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 23/106 (21%)
Query: 232 DRGPKERPRREGKPRKEKPR-------KEERPKKERPRKEERPRAARE----PREALPQR 280
+RG + +P G P + R K+E+ KER ++E+ ARE R++LP
Sbjct: 387 ERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPAS 446
Query: 281 WESREGGHRPWARDSRDAEPRKK-------QAWVSPRRPDEEQRPG 319
+R A + + P+ K +W P P PG
Sbjct: 447 PRARLS-----ASTASELSPKSKARPSSPSTSWHRPASPCPSPGPG 487
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 49.7 bits (117), Expect = 4e-06
Identities = 62/253 (24%), Positives = 93/253 (36%), Gaps = 32/253 (12%)
Query: 27 LAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAG 86
LAE +D P S S P ++ A+GP P+ + P PG +E
Sbjct: 245 LAEDAKDVPGGGP----SSSAPAGAE-ADGPKAS--PEARPQIPTKPRVPGKLQELASPP 297
Query: 87 ASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRD 146
A + RK +++ P P P P + ++ + + + LV L L +
Sbjct: 298 AGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHEL--PVPKPRGT 355
Query: 147 AVPGEAALQARVPEPWVPPSSA-PREPSSPLPKFEAQAPPS--------------APPAP 191
P E R PW+ A P++ +PLP + PPS A P+P
Sbjct: 356 PKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSP 415
Query: 192 RAEAEVRPKIPGSREAAENDEEEPGE---ATGEAVREDRVTLADRGPKERPRREGKPRKE 248
A E +P P E + +EE P AT A+ T PK G
Sbjct: 416 TASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPEST-----PKSLHPWYGITPTS 470
Query: 249 KPRKEERPKKERP 261
P+ ++RP P
Sbjct: 471 SPKTKKRPAPRAP 483
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/257 (21%), Positives = 88/257 (34%), Gaps = 35/257 (13%)
Query: 29 ETQEDRASATPRLADSGSVPHDSQVAEGPS-----VDTRPKKMEKEPAARGTPGTGKERL 83
E +E+ A A P LA S ++ H + T K +K PA R
Sbjct: 432 EDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAP-------- 483
Query: 84 KAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQL 143
ASP ++ A + + + PP P PALS E L+S A + +L
Sbjct: 484 --SASPLALHASRLSHSEPP--SATPSPALSVES------------LSSESASQTAGAEL 527
Query: 144 CRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPG 203
+++ + V P P + +S L P P+A + P+ G
Sbjct: 528 LEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRG 587
Query: 204 SREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRK 263
S +P + A + + DR P P + K +E P +P
Sbjct: 588 S------SGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSP 641
Query: 264 EERPRAAREPREALPQR 280
P + + + P R
Sbjct: 642 AASPATKKATKGSKPVR 658
Score = 33.5 bits (75), Expect = 0.27
Identities = 42/188 (22%), Positives = 69/188 (36%), Gaps = 30/188 (15%)
Query: 145 RDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGS 204
R +P + + ++ E PP+ P +P P+ +++ APP PR P S
Sbjct: 277 RPQIPTKPRVPGKLQELASPPAGRP----TPAPRKASESTTPAPPTPR---------PRS 323
Query: 205 REAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPK-----KE 259
EN E+ G ++ R + P +PR KP + P + P +
Sbjct: 324 SLQQENLVEQAGSSSLVNGRLHEL------PVPKPRGTPKPSEGTPAPRKDPPWITLVQA 377
Query: 260 RPRKEERP-RAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRP 318
P+K+ P + P + GG A+ S A K P P EE+
Sbjct: 378 EPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESK-----PYNPFEEEEE 432
Query: 319 GSRQKLRA 326
++ A
Sbjct: 433 DKEEEAPA 440
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 49.3 bits (116), Expect = 5e-06
Identities = 77/299 (25%), Positives = 112/299 (37%), Gaps = 37/299 (12%)
Query: 8 WEELDGGLGSCQALEDHSAL----AETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRP 63
W+ LD G+ + QA + S + +ET PR + S S + G + R
Sbjct: 586 WDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRG 645
Query: 64 --KKMEKEPA-ARGTPGTG-----KERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSE 115
+ + +PA G GT +E + G+SP + P + P P P S
Sbjct: 646 AGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGG--GPSRRGPLPCPLCSR 703
Query: 116 ELPWGDLSLNKCLVLASLVALLGSAFQL-CRDAVPGEAALQAR----VPEPWVPPSSAPR 170
E L L + VA G L C +++L+A P PP+SAP
Sbjct: 704 EGACSCLPLER----GDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPP 759
Query: 171 EPSSPL-----PKFEAQAPPSA----PPAPRAEAE--VRPKIPGSREAAENDEEEPGEAT 219
E PL P++ + PP A PP PRA A+ P P + + + PG
Sbjct: 760 EFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKP 819
Query: 220 GEAVREDRVTLADRGP---KERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPRE 275
G++ E + G EG PR P + P RP + P PRE
Sbjct: 820 GDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPRE 878
Score = 33.5 bits (75), Expect = 0.27
Identities = 36/138 (26%), Positives = 47/138 (34%), Gaps = 14/138 (10%)
Query: 172 PSSPLPKFEAQAP------PSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVRE 225
P P PK P P APRA R + A PG G V
Sbjct: 1103 PLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDA 1162
Query: 226 DRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESRE 285
+ + P+ P P + +PR+ E P R R E P E P +SR
Sbjct: 1163 KAGWVDNTRPQPPPPPLPPPPEAQPRRLE-PAPPRARPEVAP-------EGEPGAPDSRA 1214
Query: 286 GGHRPWARDSRDAEPRKK 303
GG + D +P +K
Sbjct: 1215 GGDTALSGDGDPPKPERK 1232
Score = 30.4 bits (67), Expect = 2.3
Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 19/91 (20%)
Query: 162 WVPPSSAPREPSSPLPKF-EAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATG 220
WV ++ P+ P PLP EAQ P PRA EV P E EPG
Sbjct: 1166 WVD-NTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAP------------EGEPGAPDS 1212
Query: 221 EAVREDRVTLADRGPKERPRREGKPRKEKPR 251
A + L+ G +P R+G E PR
Sbjct: 1213 RAGGD--TALSGDGDPPKPERKG---PEMPR 1238
Score = 30.0 bits (66), Expect = 3.0
Identities = 32/103 (31%), Positives = 37/103 (35%), Gaps = 21/103 (20%)
Query: 102 PPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPG----------E 151
PP PPPPPP PW + A L S F L D PG E
Sbjct: 445 PPRPPPPPPPPRDGPFPWPWPPAHS----APRPGTLSSPFPLL-DGFPGADPDDVLTVTE 499
Query: 152 AALQARVPEPWVPP-SSAPREPSSPLPKFEAQAPPSAPPAPRA 193
++ + W A R +P A P SAPPAP A
Sbjct: 500 SSRGLNLECLWEKARRGAGRGGGAP-----AWQPASAPPAPHA 537
Score = 29.3 bits (64), Expect = 5.1
Identities = 62/273 (22%), Positives = 92/273 (33%), Gaps = 29/273 (10%)
Query: 36 SATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGT-PGTGKERLKAGASPRSVPA 94
+A+P + + P + GP + E + G PG G + PR+ P
Sbjct: 796 AASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPE 855
Query: 95 RKK-AQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVA-----LLGSAFQLCRDAV 148
PP P P P E P + ++ +L SL LLG R+
Sbjct: 856 PPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETG 915
Query: 149 PGEAAL----QARVP----EPWV-------PPSSAPREPSSPLPKFEAQAPPSAPPAPRA 193
P +A + +VP +P V P S P + L + +AP A
Sbjct: 916 PRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAEN 975
Query: 194 EAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKE 253
A P+ + EN E P +A+ + + G K P K + +
Sbjct: 976 GALGSPE--REEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVS 1033
Query: 254 ERPKKERPRKEERPR-----AAREPREALPQRW 281
E PR ERP A P E P+ W
Sbjct: 1034 ENGGLRFPRNTERPPETGPWRAPGPWEKTPESW 1066
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 48.9 bits (115), Expect = 6e-06
Identities = 68/286 (23%), Positives = 104/286 (36%), Gaps = 39/286 (13%)
Query: 58 SVDTRPKKME--KEPAARGTPGTGKERLKAGASPRSVP-ARKKAQTAPPLQPPP------ 108
+VD P + +PA + + K A+ + P A +KA+ AP QPP
Sbjct: 1748 NVDPEPDSTQPLSKPAQKSEEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEV 1807
Query: 109 -PPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSS 167
PP A ++ P +K V A+ V+++ R+ + S+
Sbjct: 1808 DPPVAAKDKKP-NKSKRSKTPVQAAAVSIVEKPV----------TRKSERIDREKLKRSN 1856
Query: 168 APREPSSPLPKFEAQAPPSAPPAPRAEA----EVRPKIPGSREAAEN--------DEEEP 215
+PR + L + + +A A + A P +P SR N + E
Sbjct: 1857 SPRGEAQKLLELKMEAEKITRTASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDHEN 1916
Query: 216 GEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPRE 275
E V + RVT R ER +E PR+ PK R EE A+EP E
Sbjct: 1917 RSPVKEPVEQPRVT---RKRLERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAE 1973
Query: 276 AL--PQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPG 319
L P+ W S + A + K + V RP+ G
Sbjct: 1974 TLKPPEGWRSPR-SQKTAAGGGPQGKKGKNEPKVDATRPEATTEVG 2018
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/147 (27%), Positives = 53/147 (36%), Gaps = 12/147 (8%)
Query: 151 EAALQARVPEPWVPPSSAPREPSS-PLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAE 209
E A + PE W P S P K P P A EV P+I G +E++
Sbjct: 1970 EPAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNEPKVDATRPEATTEVGPQI-GVKESSM 2028
Query: 210 NDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKE----- 264
+ EA E R+ + D+ P E E +K P K + K+ R R
Sbjct: 2029 EPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVD 2088
Query: 265 -----ERPRAAREPREALPQRWESREG 286
+ AA PR A Q E G
Sbjct: 2089 KSASLKNVDAAVSPRGAAAQAGERESG 2115
Score = 33.1 bits (74), Expect = 0.35
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 41/141 (29%)
Query: 71 AARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQP-----PPPPPALSEELPWGDLSLN 125
AA+G P G+ P+ V + + AQ APP P P PP S ++P
Sbjct: 3340 AAQGPPPEGEPL----QPPQPVQSTQPAQPAPPCPPSQLGQPGQPP--SSKMP------- 3386
Query: 126 KCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVP--PSSAPREPSSPLPKFEAQA 183
Q+ ++A Q V +P +P P++ P EP + + + +A+
Sbjct: 3387 ----------------QVSQEA----KGTQTGVEQPRLPAGPANRPPEPHTQVQRAQAET 3426
Query: 184 PPSAPPAPRAEAEVRPKIPGS 204
P++ P+P ++P +P S
Sbjct: 3427 GPTSFPSP-VSVSMKPDLPVS 3446
Score = 30.4 bits (67), Expect = 2.3
Identities = 39/173 (22%), Positives = 62/173 (35%), Gaps = 33/173 (19%)
Query: 52 QVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPR-SVPARKKAQTA-PPLQPPPP 109
Q E P + + +K P T K +S SV R + + PP PPPP
Sbjct: 2376 QHPEAPQEEKQSEKPHSTPPQSCTSDLSKIPSTENSSQEISVEERTPTKASVPPDLPPPP 2435
Query: 110 PPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAP 169
PA +E P ++ + ++ P +P P +P +A
Sbjct: 2436 QPAPVDEEPQARFRVHSII-----------------ESDPVTPPSDPSIPIPTLPSVTAA 2478
Query: 170 REPSSPLPKFEAQAPPSAPPA-----------PRAEAEVRPKIPGSREAAEND 211
+ SP P P +PP PRA++ P +P +A++ D
Sbjct: 2479 K--LSP-PVASGGIPHQSPPTKVTEWITRQEEPRAQSTPSPALPPDTKASDVD 2528
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 48.9 bits (115), Expect = 6e-06
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 22/130 (16%)
Query: 203 GSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKK---- 258
G+ + ++EPG+ G A DR PK + +RE K KE PRK + PKK
Sbjct: 89 GTGVKKKRKKKEPGDQEGAAKGSK-----DREPKPKRKREPKEPKE-PRKAKEPKKAKEH 142
Query: 259 ERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRP 318
+ P++++ + AR+PREA + E++E R D+ R K R+ +EQ P
Sbjct: 143 KEPKQKDGAKKARKPREASGTK-EAKE------KRSCTDSAARTKS-----RKASKEQGP 190
Query: 319 GSRQKLRAGK 328
+K + GK
Sbjct: 191 TPVEKKKKGK 200
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 48.5 bits (114), Expect = 8e-06
Identities = 52/182 (28%), Positives = 66/182 (36%), Gaps = 23/182 (12%)
Query: 34 RASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGT------GKERLKAG- 86
R A P L S P + P + P ++ P+ TP + G L+A
Sbjct: 280 RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339
Query: 87 -------ASPRSVPARKK--AQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALL 137
SP + P + A PPLQ PP PPA P S LA V LL
Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA--VHLL 397
Query: 138 GSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEV 197
+ F + P +QA P PP S P S P A P PP+P A +
Sbjct: 398 QAPF-----SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452
Query: 198 RP 199
P
Sbjct: 453 SP 454
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/144 (27%), Positives = 52/144 (36%), Gaps = 12/144 (8%)
Query: 63 PKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPP---PPPALSEELPW 119
P P ++ P L+ SP + P + T PP PPP PP L++ P
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 120 GDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKF 179
L L AL PG+A P P ++ P + L
Sbjct: 480 AP----PALATPPLQALPSPPASF-----PGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 180 EAQAPPSAPPAPRAEAEVRPKIPG 203
Q PPS P +P +A RP PG
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPG 554
Score = 43.9 bits (102), Expect = 2e-04
Identities = 59/232 (25%), Positives = 80/232 (34%), Gaps = 55/232 (23%)
Query: 80 KERLKAGASPRSVPARKKAQTAP--PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALL 137
+++ KAGA+ R+ AR P P P PPPP V + + +L
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPP-----------------VTPAALRVL 47
Query: 138 GSAFQLCRDAVPGEAAL--QARVPE--PWVPPSSAPREPSS------PLPKFEAQAPPSA 187
G+A + R + A A +PE P P+ R P+S P K + P S+
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS 107
Query: 188 P--------PAP---------------RAEAEVRPKIPGSREAAENDEE--EPGEATGEA 222
P P P R +A PK A D PG +
Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 167
Query: 223 VREDRVTLADRG-PKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREP 273
R R + G P+ P +P E PRK E E P A R P
Sbjct: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 219
Score = 42.0 bits (97), Expect = 8e-04
Identities = 52/203 (25%), Positives = 70/203 (34%), Gaps = 31/203 (15%)
Query: 36 SATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPAR 95
SA PR G S +E + + P + A G L + A+P S PAR
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245
Query: 96 K--KAQTAP--PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVP-- 149
A+ P P P P P + L ++ + +L L S + P
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 150 --GEAALQARVPEPWVPPSSA----------------PREPSSPLPKFEAQAPPS----- 186
+LQ P PPS A P P SPL QAPP+
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 187 --APPAPRAEAEVRPKIPGSREA 207
APP+P A + P S +A
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQA 388
Score = 30.8 bits (68), Expect = 1.7
Identities = 38/141 (26%), Positives = 51/141 (36%), Gaps = 23/141 (16%)
Query: 91 SVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAV-- 148
SV + P PPPP + S L DL+ + ++ L G A
Sbjct: 558 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 617
Query: 149 -PGEAALQARVPEPW----VPPSSAPREPSSPLPK---------------FEAQAPPSAP 188
P +A L A P W PP + P +PLP +E + P SA
Sbjct: 618 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 677
Query: 189 PAPRA-EAEVRPKIPGSREAA 208
PAP A + P G + AA
Sbjct: 678 PAPGALDPGPSPGTSGGKAAA 698
Score = 30.4 bits (67), Expect = 2.3
Identities = 58/244 (23%), Positives = 83/244 (34%), Gaps = 46/244 (18%)
Query: 45 GSVPHDSQVAEGPSVDTRPK---KMEKEPAARGT-PGTGKERLKAGASPRSVPARKKAQT 100
G+ +S GP+ +RP + E+ P A+ T PG P S P R T
Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPG-----------PVSSPGRASGTT 115
Query: 101 AP-PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE-------- 151
P PL + E + G K AL A + PG
Sbjct: 116 RPGPLGQKGLRISAEETVARG-----KATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 170
Query: 152 ---AALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAA 208
A + +P P PS+ PR P+ K + A + P A RP G
Sbjct: 171 SRAAGTEVGLPRP--APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--- 225
Query: 209 ENDEEEPGEATGEAVREDRVTLADRGPKER--PRREGKPRKEKPRKEER---PKKERPRK 263
+ P + + + A GP R PR P + KP+ + P+ PRK
Sbjct: 226 ----QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281
Query: 264 EERP 267
+ P
Sbjct: 282 DAAP 285
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/186 (25%), Positives = 66/186 (35%), Gaps = 23/186 (12%)
Query: 37 ATPRLADSGSVPHDS---------QVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGA 87
A+P ++ S + P + QV P P P + P L+
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQVPP 739
Query: 88 SPRSVPARKKAQT----------APPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALL 137
SP + P + T APPLQ PP PPA LP L+ +L
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA---SLPMSPLAKPPPQAPPALATPP 796
Query: 138 GSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEV 197
A + PG+A P P ++ P + L Q PPS P +P +A
Sbjct: 797 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 856
Query: 198 RPKIPG 203
RP PG
Sbjct: 857 RPPTPG 862
Score = 43.5 bits (101), Expect = 3e-04
Identities = 70/275 (25%), Positives = 91/275 (33%), Gaps = 25/275 (9%)
Query: 21 LEDHSALAETQEDRASA---TPRLADSGSVPHDSQVAEGPSVDTRPKKMEKE----PAAR 73
LE+ +LA ASA TP L ++ P + PS T P P +
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHL-ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 74 GTPGTGKERLKAGASPRSVPARKKAQTAPP------LQPPPPPPALSEELPWGDLSLNKC 127
P L+ SP P APP LQ PP PPA P S
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
Query: 128 LVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSA 187
LA V LL + F + P +QA P PP S P S P A P
Sbjct: 654 NALA--VHLLQAPF-----SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 188 PPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRK 247
PP+P A + P +A P + ++ + P P P
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 248 EKPRKEERPKKERPRKEERPRA----AREPREALP 278
+ P P + P+A A P +ALP
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Score = 40.4 bits (93), Expect = 0.002
Identities = 48/184 (26%), Positives = 68/184 (36%), Gaps = 18/184 (9%)
Query: 36 SATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPAR 95
SA PR G S +E + + P + A G L + A+P S PAR
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 96 K--KAQTAP--PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGE 151
A+ P P P P P + L ++ + +L L S A P
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL-----ATPSP 309
Query: 152 AALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAEND 211
+ +AR P PP +A ++PLP +PP A P P A P P S + +
Sbjct: 310 SGTKAR---PVPPPDNA----ATPLPATLPPSPPLATPLPLAPPS--PSAPPSLQTLPSP 360
Query: 212 EEEP 215
P
Sbjct: 361 PATP 364
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/241 (22%), Positives = 76/241 (31%), Gaps = 64/241 (26%)
Query: 80 KERLKAGASPRSVPARKKAQTAP--PLQPPPPPPALSEELPWGDLSLNKCLVLASLVALL 137
+++ KAGA+ R+ AR P P P PPPP V + + +L
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPP-----------------VTPAALRVL 47
Query: 138 GSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPS------APPAP 191
G+A + R + A P P + P + + A PP+ APPA
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
Query: 192 -----------RAEAEVRPKIPGSREAAENDEEE-------------------------- 214
RA RP G + + EE
Sbjct: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 167
Query: 215 -PGEATGEAVREDRVTLADRG-PKERPRREGKPRKEKPRKEERPKKERPRKEERPRAARE 272
PG + R R + G P+ P +P E PRK E E P A R
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 273 P 273
P
Sbjct: 228 P 228
Score = 34.7 bits (78), Expect = 0.12
Identities = 40/147 (27%), Positives = 58/147 (39%), Gaps = 23/147 (15%)
Query: 57 PSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARK--KAQTAPPLQPPPPPPALS 114
PS+ T P P ++ P ++A S +++P + + T+P LQ PP P ALS
Sbjct: 352 PSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
Query: 115 EELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSS 174
SL L S +F QA + P P S+ P P
Sbjct: 411 --------SLQATTSLGSPTLQATHSF-----LTMSPRQTQASLTSPSRPASTPPDSP-- 455
Query: 175 PLPKFEAQAPPSAPPAPRAEAEVRPKI 201
PL QAP S P +P + + P +
Sbjct: 456 PL-----QAPLSLPASPPLQTSLSPAV 477
Score = 30.8 bits (68), Expect = 1.7
Identities = 52/233 (22%), Positives = 72/233 (30%), Gaps = 42/233 (18%)
Query: 67 EKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGD----- 121
E P A T G + P PA + + APP + P P S G
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRP---PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128
Query: 122 LSLNKCLVLASLVALLGSAFQLC-RDAVPGEAALQARVPEPWVP---------------- 164
L + A G A + R A+ A P P P
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 165 -----PSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEAT 219
PS+ PR P+ K + A + P A RP G + P +
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL-------QRPASRS 241
Query: 220 GEAVREDRVTLADRGPKER--PRREGKPRKEKPRKEER---PKKERPRKEERP 267
+ + A GP R PR P + KP+ + P+ PRK+ P
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Score = 30.8 bits (68), Expect = 1.7
Identities = 38/141 (26%), Positives = 51/141 (36%), Gaps = 23/141 (16%)
Query: 91 SVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAV-- 148
SV + P PPPP + S L DL+ + ++ L G A
Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Query: 149 -PGEAALQARVPEPW----VPPSSAPREPSSPLPK---------------FEAQAPPSAP 188
P +A L A P W PP + P +PLP +E + P SA
Sbjct: 926 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 985
Query: 189 PAPRA-EAEVRPKIPGSREAA 208
PAP A + P G + AA
Sbjct: 986 PAPGALDPGPSPGTSGGKAAA 1006
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/190 (25%), Positives = 75/190 (39%), Gaps = 21/190 (11%)
Query: 141 FQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPK 200
F+L R+ +P + QA V EP V A R+P + E P P P E
Sbjct: 1173 FKLSREIMP--VSTQACVIEPIVSIPKAGRKPKIQESE-ETVEPKEDMPLPEERKEEEEM 1229
Query: 201 IPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPR--------K 252
+ EA E +EE+ A+ E ++ E E + +EKPR +
Sbjct: 1230 QAEAEEAEEGEEED--AASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSE 1287
Query: 253 EERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRP 312
EE+ + E P EE AA E + + + GH +KK+ P R
Sbjct: 1288 EEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHL--------ESTKKKELEEQPTRE 1339
Query: 313 DEEQRPGSRQ 322
D ++ PG ++
Sbjct: 1340 DVKEEPGVQE 1349
Score = 36.6 bits (83), Expect = 0.032
Identities = 32/153 (20%), Positives = 59/153 (38%), Gaps = 12/153 (7%)
Query: 13 GGLGSCQALEDHSALAETQEDRASATPRLADSGSV-PHDSQVAEGPS---VDTRPKKMEK 68
GGL S +L S + Q ++ + SV P + + P V+ P ++
Sbjct: 1590 GGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQ 1649
Query: 69 EPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQP--PPPPPALSEELPWGDLSLNK 126
+P + +P+ P +++ Q P QP PPPPP ++ P S+N
Sbjct: 1650 QPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNN 1709
Query: 127 CLVLASLVALLGSAFQLCRDAVPGEAALQARVP 159
A ++ ++ G ++ R+P
Sbjct: 1710 SFTPAPMI------MEIPESGSTGNISIYERIP 1736
Score = 35.8 bits (81), Expect = 0.054
Identities = 41/238 (17%), Positives = 84/238 (35%), Gaps = 60/238 (25%)
Query: 7 AWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKM 66
A+++ + L +CQ L+ + TQ D + D + H+S ++ SV + P +
Sbjct: 1442 AYQDCEETLAACQTLQSY-----TQADEDPQMSMVEDCHASEHNSPIS---SVQSHPSQS 1493
Query: 67 EKEPAARGTPG--TGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWG---- 120
+ ++ P +G ++ S P+ + +T+P + P + + G
Sbjct: 1494 VRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1553
Query: 121 -------------------------------------------DLSLNKCLVLASLVALL 137
L+ + C+V + ++
Sbjct: 1554 GSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMG 1613
Query: 138 GSAFQLCRDAVPGEAALQARVPEPWV---PPSSAPREPSSPLPKFEAQAPPSAPPAPR 192
S + + +V A + P+ V PPS+ ++P P P+ PP PAP+
Sbjct: 1614 SSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQ 1671
Score = 32.3 bits (72), Expect = 0.60
Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 15/155 (9%)
Query: 165 PSSAPREPSSPLPKFEAQAPP--SAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEA 222
P+++P + SS P+ E + P PR E R +E E + EE +A E
Sbjct: 1250 PAASPAD-SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 223 VREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAA--REPREALPQR 280
+ D D + K +E+P +E+ KE P +E A ++ RE + +
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTRED--VKEEPGVQESFLDANMQKSREKIKDK 1366
Query: 281 WESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEE 315
E+ DS + +P + VS + E
Sbjct: 1367 EETE--------LDSEEEQPSHDTSVVSEQMAGSE 1393
Score = 31.6 bits (70), Expect = 1.0
Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 7/101 (6%)
Query: 214 EPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAR-- 271
E EAT E E L +E+P ++GKP K R E + R + ++ P A +
Sbjct: 904 EKSEATQEQYTESEEQLV--ASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCR 961
Query: 272 --EPREALPQRW-ESREGGHRPWARDSRDAEPRKKQAWVSP 309
E E LP+R+ E R ++ S + E + SP
Sbjct: 962 LTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSP 1002
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/190 (25%), Positives = 75/190 (39%), Gaps = 21/190 (11%)
Query: 141 FQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPK 200
F+L R+ +P + QA V EP V A R+P + E P P P E
Sbjct: 1173 FKLSREIMP--VSTQACVIEPIVSIPKAGRKPKIQESE-ETVEPKEDMPLPEERKEEEEM 1229
Query: 201 IPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPR--------K 252
+ EA E +EE+ A+ E ++ E E + +EKPR +
Sbjct: 1230 QAEAEEAEEGEEED--AASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSE 1287
Query: 253 EERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRP 312
EE+ + E P EE AA E + + + GH +KK+ P R
Sbjct: 1288 EEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHL--------ESTKKKELEEQPTRE 1339
Query: 313 DEEQRPGSRQ 322
D ++ PG ++
Sbjct: 1340 DVKEEPGVQE 1349
Score = 36.6 bits (83), Expect = 0.032
Identities = 32/153 (20%), Positives = 59/153 (38%), Gaps = 12/153 (7%)
Query: 13 GGLGSCQALEDHSALAETQEDRASATPRLADSGSV-PHDSQVAEGPS---VDTRPKKMEK 68
GGL S +L S + Q ++ + SV P + + P V+ P ++
Sbjct: 1590 GGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQ 1649
Query: 69 EPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQP--PPPPPALSEELPWGDLSLNK 126
+P + +P+ P +++ Q P QP PPPPP ++ P S+N
Sbjct: 1650 QPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCSMNN 1709
Query: 127 CLVLASLVALLGSAFQLCRDAVPGEAALQARVP 159
A ++ ++ G ++ R+P
Sbjct: 1710 SFTPAPMI------MEIPESGSTGNISIYERIP 1736
Score = 35.8 bits (81), Expect = 0.054
Identities = 41/238 (17%), Positives = 84/238 (35%), Gaps = 60/238 (25%)
Query: 7 AWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKM 66
A+++ + L +CQ L+ + TQ D + D + H+S ++ SV + P +
Sbjct: 1442 AYQDCEETLAACQTLQSY-----TQADEDPQMSMVEDCHASEHNSPIS---SVQSHPSQS 1493
Query: 67 EKEPAARGTPG--TGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWG---- 120
+ ++ P +G ++ S P+ + +T+P + P + + G
Sbjct: 1494 VRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1553
Query: 121 -------------------------------------------DLSLNKCLVLASLVALL 137
L+ + C+V + ++
Sbjct: 1554 GSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMG 1613
Query: 138 GSAFQLCRDAVPGEAALQARVPEPWV---PPSSAPREPSSPLPKFEAQAPPSAPPAPR 192
S + + +V A + P+ V PPS+ ++P P P+ PP PAP+
Sbjct: 1614 SSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQ 1671
Score = 32.3 bits (72), Expect = 0.60
Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 15/155 (9%)
Query: 165 PSSAPREPSSPLPKFEAQAPP--SAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEA 222
P+++P + SS P+ E + P PR E R +E E + EE +A E
Sbjct: 1250 PAASPAD-SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 223 VREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAA--REPREALPQR 280
+ D D + K +E+P +E+ KE P +E A ++ RE + +
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTRED--VKEEPGVQESFLDANMQKSREKIKDK 1366
Query: 281 WESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEE 315
E+ DS + +P + VS + E
Sbjct: 1367 EETE--------LDSEEEQPSHDTSVVSEQMAGSE 1393
Score = 31.6 bits (70), Expect = 1.0
Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 7/101 (6%)
Query: 214 EPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAR-- 271
E EAT E E L +E+P ++GKP K R E + R + ++ P A +
Sbjct: 904 EKSEATQEQYTESEEQLV--ASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCR 961
Query: 272 --EPREALPQRW-ESREGGHRPWARDSRDAEPRKKQAWVSP 309
E E LP+R+ E R ++ S + E + SP
Sbjct: 962 LTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSP 1002
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.128 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,487,417
Number of Sequences: 37866
Number of extensions: 1228579
Number of successful extensions: 26047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 641
Number of HSP's successfully gapped in prelim test: 1596
Number of HSP's that attempted gapping in prelim test: 11699
Number of HSP's gapped (non-prelim): 9780
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.