Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 21361937

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361937 proline rich 7 (synaptic) [Homo sapiens]
         (274 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361937 proline rich 7 (synaptic) [Homo sapiens]                  592   e-169
gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ...    59   5e-09
gi|239753972 PREDICTED: hypothetical protein [Homo sapiens]            57   2e-08
gi|83977459 pleckstrin homology-like domain, family A, member 1 ...    56   4e-08
gi|23308699 transcription factor MAFB [Homo sapiens]                   53   3e-07
gi|239755199 PREDICTED: hypothetical protein [Homo sapiens]            53   3e-07
gi|61966923 forkhead box B2 [Homo sapiens]                             53   3e-07
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               51   1e-06
gi|59938776 cAMP responsive element binding protein 5 isoform de...    50   3e-06
gi|59938774 cAMP responsive element binding protein 5 isoform be...    50   3e-06
gi|59938772 cAMP responsive element binding protein 5 isoform ga...    50   3e-06
gi|59938770 cAMP responsive element binding protein 5 isoform al...    50   3e-06
gi|37595553 ring finger protein 111 [Homo sapiens]                     49   6e-06
gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo ...    48   1e-05
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                48   1e-05
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    47   1e-05
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    47   1e-05
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    47   1e-05
gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo ...    47   2e-05
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    46   3e-05
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    46   3e-05
gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]             45   5e-05
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    45   7e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    45   7e-05
gi|18959210 WIRE protein [Homo sapiens]                                45   7e-05
gi|12751477 forkhead box L2 [Homo sapiens]                             44   2e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   2e-04
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             44   2e-04
gi|50345831 forkhead box J3 [Homo sapiens]                             44   2e-04
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 44   2e-04

>gi|21361937 proline rich 7 (synaptic) [Homo sapiens]
          Length = 274

 Score =  592 bits (1526), Expect = e-169
 Identities = 274/274 (100%), Positives = 274/274 (100%)

Query: 1   MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLE 60
           MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLE
Sbjct: 1   MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLE 60

Query: 61  LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHH 120
           LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHH
Sbjct: 61  LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHH 120

Query: 121 ALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180
           ALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI
Sbjct: 121 ALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180

Query: 181 VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVF 240
           VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVF
Sbjct: 181 VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVF 240

Query: 241 PSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV 274
           PSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV
Sbjct: 241 PSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV 274


>gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo
           sapiens]
          Length = 828

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 54/173 (31%), Positives = 68/173 (39%), Gaps = 26/173 (15%)

Query: 65  LAGSPPGLAPPQPPPHRSRLEAPAHAHS-HPHVH--VHPLLH---HGPAQPHAHAHP--H 116
           LA SPPG     PP H      P H+ S HP +H   HP +H   H P  P  H HP  H
Sbjct: 11  LAVSPPGKICIHPPLH-----PPTHSPSIHPSIHPPTHPSIHPSIHPPTHPSIHTHPPIH 65

Query: 117 PHHHALPHPPPTHLSVPP--RPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTR 174
           PH H  P  PPTH S+ P   P  +P       S  P    ++  +  PP +S +     
Sbjct: 66  PHTHP-PIHPPTHPSIHPLIHPSIHP-------SLHPPTHSSIHPSTHPPTHSSIHPSIH 117

Query: 175 GLYRKIVTPFL--SRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPP 225
                ++ P +  S   S        PS  PL +        H P  P   PP
Sbjct: 118 PSTHPLIHPSIHPSTHSSIHPPTHSHPSTHPL-IHPSIHPPTHSPIHPSIHPP 169



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLH---HGPAQPHAHAHPHPHHHALPHPP 126
           P + P   P   S +  P H+H   H  +HP +H   H P  P  H   HP  H   H  
Sbjct: 122 PLIHPSIHPSTHSSIHPPTHSHPSTHPLIHPSIHPPTHSPIHPSIHPPTHPPTHPSIHSS 181

Query: 127 ---PTHLSVPPRPWSY 139
              PTH S+ P   S+
Sbjct: 182 IHLPTHSSIHPPTHSF 197



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 31/111 (27%), Positives = 39/111 (35%), Gaps = 23/111 (20%)

Query: 70  PGLAPP-QPPPH-----------RSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHP 117
           P + PP  PP H            S +  P H+  HP +H      H P  P  H   HP
Sbjct: 164 PSIHPPTHPPTHPSIHSSIHLPTHSSIHPPTHSFIHPSIHPPT---HSPIHPLTHPFIHP 220

Query: 118 HHHALPHPP------PTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162
              +            T +S  PRP   P  A +  S PP +   V  A P
Sbjct: 221 SDSSAASAGGVGPALQTRMSGHPRPTGSPVLALA--SHPPWHSLEVYRALP 269


>gi|239753972 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 298

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 46/164 (28%), Positives = 59/164 (35%), Gaps = 14/164 (8%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLHHGPAQPHAHA--HP--HPHHHALP 123
           P + P   PP       P H  +HP +H   HP   + P  P AH   HP  HP  H   
Sbjct: 83  PPIHPSTNPPIHPSTNPPIHPSTHPTIHPSTHPPSTYLPIHPSAHPLIHPFIHPLTHLFI 142

Query: 124 HPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTP 183
           HPPPTH  + P   S           PP Y     +  PP P+  +          ++ P
Sbjct: 143 HPPPTHSPIHPPTHSSIHLPTHLSIYPPTYPS---IHPPPTPHPSIHPPIHPSTHPLIHP 199

Query: 184 FLSRRDSAEKQEQPP--PSYKPLFLDRGYTSALHLPSAPRPAPP 225
             S   S      PP  P   P  +       +H P+ P   PP
Sbjct: 200 --STHTSTHPPTHPPTHPPSNP-SIHSSIHPPIHPPTHPSTHPP 240



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 43/166 (25%), Positives = 60/166 (36%), Gaps = 18/166 (10%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLHHGPAQPHAHAHPHPHHHALPHPPP 127
           P + P    P       P H  +HP +H   +P +H     P  H   HP  H   HPP 
Sbjct: 59  PPIHPSTHLPIHPSTHLPIHPSTHPPIHPSTNPPIHPS-TNPPIHPSTHPTIHPSTHPPS 117

Query: 128 THLSVPP------RPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIV 181
           T+L + P       P+ +P      +  PP +         PP +S +   T        
Sbjct: 118 TYLPIHPSAHPLIHPFIHP-LTHLFIHPPPTHSPI-----HPPTHSSIHLPTHLSIYPPT 171

Query: 182 TPFLSRRDSAEKQEQPP--PSYKPLFLDRGYTSALHLPSAPRPAPP 225
            P +    +      PP  PS  PL     +TS  H P+ P   PP
Sbjct: 172 YPSIHPPPTPHPSIHPPIHPSTHPLIHPSTHTST-HPPTHPPTHPP 216



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/106 (33%), Positives = 40/106 (37%), Gaps = 20/106 (18%)

Query: 69  PPGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLHHGPAQPHAHAHP--HPHHHALPH 124
           PP    P  PP  S +  P H   +P  +  +HP     P  PH   HP  HP  H L H
Sbjct: 144 PPPTHSPIHPPTHSSIHLPTHLSIYPPTYPSIHP-----PPTPHPSIHPPIHPSTHPLIH 198

Query: 125 P-------PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPP 163
           P       PPTH   P  P S P    S    PP +        PP
Sbjct: 199 PSTHTSTHPPTH--PPTHPPSNPSIHSS--IHPPIHPPTHPSTHPP 240



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 32/131 (24%), Positives = 45/131 (34%), Gaps = 9/131 (6%)

Query: 95  HVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYE 154
           H  +HP   H P  P  H   HP  H LP  P TH  + P        + +    P  + 
Sbjct: 49  HPTIHPSSTHPPIHPSTHLPIHPSTH-LPIHPSTHPPIHPSTNPPIHPSTNPPIHPSTHP 107

Query: 155 EAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSAL 214
                  PP  Y  +      L    + P             PPP++ P+       S++
Sbjct: 108 TIHPSTHPPSTYLPIHPSAHPLIHPFIHPL------THLFIHPPPTHSPIHPPT--HSSI 159

Query: 215 HLPSAPRPAPP 225
           HLP+     PP
Sbjct: 160 HLPTHLSIYPP 170



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 26/86 (30%), Positives = 32/86 (37%), Gaps = 23/86 (26%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHPHVH----------VHPLLH-----------HGPAQ 108
           P + PP P PH S +  P H  +HP +H           HP  H           H P  
Sbjct: 173 PSIHPP-PTPHPS-IHPPIHPSTHPLIHPSTHTSTHPPTHPPTHPPSNPSIHSSIHPPIH 230

Query: 109 PHAHAHPHPHHHALPHPPPTHLSVPP 134
           P  H   HP  H+  HP     + PP
Sbjct: 231 PPTHPSTHPPIHSSTHPSTYFSTHPP 256



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 10/84 (11%)

Query: 58  PLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHP 117
           PL    +   + P   PP  PP    + +  H   HP    HP  H     P  H+  HP
Sbjct: 195 PLIHPSTHTSTHPPTHPPTHPPSNPSIHSSIHPPIHP--PTHPSTH-----PPIHSSTHP 247

Query: 118 HHHALPHPP---PTHLSVPPRPWS 138
             +   HPP   P  L    RP+S
Sbjct: 248 STYFSTHPPLLSPKVLQKAFRPFS 271


>gi|83977459 pleckstrin homology-like domain, family A, member 1
           [Homo sapiens]
          Length = 401

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 1/94 (1%)

Query: 40  RRQEERLREQNLRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVH 99
           R++++ L +Q   +      +L+      P     PQ  P       P     HP+ H H
Sbjct: 296 RQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPH 355

Query: 100 PLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVP 133
           P  H  P   H H HPHPH H +PHP P   S P
Sbjct: 356 PHPHSHP-HSHPHPHPHPHPHQIPHPHPQPHSQP 388



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 23/51 (45%), Positives = 25/51 (49%), Gaps = 1/51 (1%)

Query: 75  PQPPPHRSRLEAPAHAHSHPHVHVHPLLH-HGPAQPHAHAHPHPHHHALPH 124
           PQP P   +L    H H HPH H H   H H    PH   HPHP  H+ PH
Sbjct: 339 PQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPH 389



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 3/74 (4%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTH 129
           P L P   P  + + +  +     P     P   H    PH H H HPH H  PHP P  
Sbjct: 315 PQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHPHP 374

Query: 130 LSVP---PRPWSYP 140
             +P   P+P S P
Sbjct: 375 HQIPHPHPQPHSQP 388



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 22/48 (45%), Positives = 23/48 (47%), Gaps = 8/48 (16%)

Query: 75  PQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHAL 122
           P P PH       +H HSHPH H HP  H  P  PH   H  PH H L
Sbjct: 354 PHPHPH-------SHPHSHPHPHPHPHPHQIP-HPHPQPHSQPHGHRL 393



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 22/94 (23%), Positives = 32/94 (34%), Gaps = 4/94 (4%)

Query: 76  QPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPR 135
           Q   H  + + P+     P +   P     P QP   + P P     P P P  L   P 
Sbjct: 297 QKQQHLVQQQPPSQPQPQPQLQPQPQPQPQP-QPQPQSQPQPQPQ--PKPQPQQLHPYPH 353

Query: 136 PWSYPRQAESDMSKPPCYEEAVLMAEP-PPPYSE 168
           P  +P         P  +     +  P P P+S+
Sbjct: 354 PHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQ 387


>gi|23308699 transcription factor MAFB [Homo sapiens]
          Length = 323

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 33/99 (33%), Positives = 39/99 (39%), Gaps = 8/99 (8%)

Query: 47  REQNLRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPL----- 101
           ++ N  AL L P +   +L GS P    PQP           H H H H H H       
Sbjct: 93  QQMNPEALNLTPEDAVEALIGSHP---VPQPLQSFDSFRGAHHHHHHHHPHPHHAYPGAG 149

Query: 102 LHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYP 140
           + H    PHAH H H HH A P P          P S+P
Sbjct: 150 VAHDELGPHAHPHHHHHHQASPPPSSAASPAQQLPTSHP 188


>gi|239755199 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 279

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 37/127 (29%), Positives = 45/127 (35%), Gaps = 21/127 (16%)

Query: 70  PGLAPPQPPP---------HRSRLEAPAHAHSHPHVH--VHPLLH-------HGPAQPHA 111
           P + PP  P          H      P H  +HP +H  +HP  H       H P  P  
Sbjct: 141 PSIHPPTHPSIHASTHPLIHHPSTHPPTHPSTHPSIHPTIHPRAHPPIHPSIHSPTHPSI 200

Query: 112 HAHPHPHHHALPHP---PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSE 168
           H   HP  H L HP   P  H ++ P  +  PR   S  S   C   +      P     
Sbjct: 201 HPSTHPSTHPLTHPSTYPSIHPTIHPLTYPLPRANASVDSHLQCGRSSEERKVNPARVRF 260

Query: 169 VLTDTRG 175
           VLT T G
Sbjct: 261 VLTSTLG 267



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 8/90 (8%)

Query: 58  PLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLH---HGPAQPHAH 112
           P+  EG L     G+ P   P        P H   HP +H  +HP +H   H P +P  H
Sbjct: 33  PVSGEGLLGQGAEGIGPSIHPSIHPSTHPPIHPSIHPSIHPSIHPPVHPSIHPPTRPSIH 92

Query: 113 AHPHPHHHALPHPPPTHLSVPP--RPWSYP 140
              HP  H   H P TH S+ P   P  YP
Sbjct: 93  PSIHPPVHLSTH-PSTHPSIHPPIHPSIYP 121



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 7/74 (9%)

Query: 74  PPQPPPHRSRLEAPAHAHSHPHVHV--HPLLHHGPAQPHAHAHPHPHHHALPHP---PPT 128
           P   PP    +    H  +HP +H   HPL+HH    P  H   HP  H   HP   PP 
Sbjct: 129 PSIHPPIHPFIHPSIHPPTHPSIHASTHPLIHHPSTHPPTHPSTHPSIHPTIHPRAHPPI 188

Query: 129 HLSV--PPRPWSYP 140
           H S+  P  P  +P
Sbjct: 189 HPSIHSPTHPSIHP 202



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 10/72 (13%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLH-------HGPAQPHAHAHPHPHHH 120
           P + PP  P     +  P H  +HP  H  +HP +H       H    P  H   HP  H
Sbjct: 81  PSIHPPTRPSIHPSIHPPVHLSTHPSTHPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIH 140

Query: 121 ALPHPPPTHLSV 132
              H PPTH S+
Sbjct: 141 PSIH-PPTHPSI 151


>gi|61966923 forkhead box B2 [Homo sapiens]
          Length = 432

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 29/132 (21%)

Query: 32  SFLRRRLKRRQEERLREQNLRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAH 91
           SFLRRR           +  + L  +   L      S PG  P              H H
Sbjct: 101 SFLRRR-----------KRFKVLRADHTHLHAGSTKSAPGAGPG------------GHLH 137

Query: 92  SHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPP 151
            H H H H   HH     HA AH H HHH  P PPP     PP    Y  Q      +PP
Sbjct: 138 PHHHHHPHHHHHH-----HAAAHHHHHHHP-PQPPPPPPPPPPHMVHYFHQQPPTAPQPP 191

Query: 152 CYEEAVLMAEPP 163
            +  +    +PP
Sbjct: 192 PHLPSQPPQQPP 203


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 32/94 (34%), Positives = 41/94 (43%), Gaps = 13/94 (13%)

Query: 72  LAPPQPPPHRSRLEAPAHA----HSHPHVHVH-------PLLHHGPAQPHAHAHPHPHHH 120
           L PP PPPH+ + + P       H  PH   H       P   H P  P  H H H HHH
Sbjct: 582 LHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHH 641

Query: 121 -ALPHPPPTHLSVPP-RPWSYPRQAESDMSKPPC 152
            ++P PP   +S P  RP     Q ++  S+  C
Sbjct: 642 LSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQC 675



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 9/101 (8%)

Query: 70  PGLAPPQPPP--HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHP-- 125
           P L PP P    H S+   P  A + P +        GP QP    H  P+     HP  
Sbjct: 530 PALQPPGPVGILHFSQ---PGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586

Query: 126 PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPY 166
           PP H   P +P   P        +PP   +     +PPP +
Sbjct: 587 PPPHQPQPQQPQQQPPPQHQPPHQPP--HQPPPQHQPPPQH 625



 Score = 32.0 bits (71), Expect = 0.60
 Identities = 51/207 (24%), Positives = 65/207 (31%), Gaps = 60/207 (28%)

Query: 63  GSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVH-VHPLLHHGPAQPHAHAHPHPHHHA 121
           G +    P L P QPP      +AP      P    +  L    P QP      HPHH  
Sbjct: 299 GRMKDHRPALLPTQPPVVP---QAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQ-HPHH-- 352

Query: 122 LPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIV 181
            P PP                    M  PP  E   +M  PPP                V
Sbjct: 353 -PSPP------------------QGMHMPPQLETPRMMMTPPP----------------V 377

Query: 182 TPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVFP 241
           TP           +QP   +          + + +P  P P+ P PA+  Q   G   FP
Sbjct: 378 TP-----------QQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFP 426

Query: 242 SWTDSELSS------REPLEHGAWRLP 262
             T   + +      R PL+   WR P
Sbjct: 427 QHTPGPVPNSFSQPPRLPLQ-DQWRAP 452



 Score = 32.0 bits (71), Expect = 0.60
 Identities = 42/171 (24%), Positives = 61/171 (35%), Gaps = 39/171 (22%)

Query: 69  PPGLAPPQ----PPPHRSRLEAPAHAHSHPHVH------VHPLLHHGPAQPHAHAHPH-- 116
           PP L  P+    PPP     + P + H +PH        V   L   P+QP     P   
Sbjct: 362 PPQLETPRMMMTPPPVTP--QQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRF 419

Query: 117 ------PHHHALPHPPPTHLSVPPR-----PWSYPRQAES------DMSKPPCYEEAVLM 159
                 P H   P P P   S PPR      W  P   +        +S  P +   + +
Sbjct: 420 PGPPEFPQH--TPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFL 477

Query: 160 AE----PPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP--PSYKPL 204
            +    PPPP   +L  +  +  +   PF     +  +Q Q P  P  +P+
Sbjct: 478 EQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPV 528



 Score = 32.0 bits (71), Expect = 0.60
 Identities = 35/130 (26%), Positives = 47/130 (36%), Gaps = 16/130 (12%)

Query: 47  REQNLRALELEPLELEGSLAGSPPGLAPPQP--PPHRSRLEAPAHAH--SHPHVHVHPLL 102
           RE+ +R   L+P    G L  S PG A  +P  PP +  L  P      +H   ++   L
Sbjct: 524 RERPVRPA-LQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPL 582

Query: 103 HHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPP-------CYEE 155
           H     PH      P       PPP H      P   P Q +     PP        +  
Sbjct: 583 HPPLPPPHQPQPQQPQQQ----PPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHH 638

Query: 156 AVLMAEPPPP 165
              ++ PPPP
Sbjct: 639 HHHLSVPPPP 648


>gi|59938776 cAMP responsive element binding protein 5 isoform delta
           [Homo sapiens]
          Length = 369

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%)

Query: 79  PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138
           PH+ +   P H H +PH H HP  H  P   H   HPH H H+  H  P H    P P  
Sbjct: 139 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 196

Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198
           +    ++ +S      +     +PP P       T G  R++V             ++ P
Sbjct: 197 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 235

Query: 199 PSYKPLFLDRGYTSA 213
              +  FL+R   +A
Sbjct: 236 DERRRKFLERNRAAA 250



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%)

Query: 78  PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126
           PPH        H H HP  H HP  HH    PH    +H H HP HH   PHPP      
Sbjct: 146 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 201

Query: 127 -----------PTHLSVPPRP 136
                      PT    PP+P
Sbjct: 202 AQVSPATQQMQPTQTIQPPQP 222



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 82  SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139
           SR +   H H H H H H  L   P  P+ H H HP HH  PHP P H    P   S+
Sbjct: 125 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 178



 Score = 32.7 bits (73), Expect = 0.35
 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%)

Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162
           H H+HPH H    PH P  H    P    +P Q     + P  +  + L A P
Sbjct: 134 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 185


>gi|59938774 cAMP responsive element binding protein 5 isoform beta
           [Homo sapiens]
          Length = 501

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%)

Query: 79  PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138
           PH+ +   P H H +PH H HP  H  P   H   HPH H H+  H  P H    P P  
Sbjct: 271 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 328

Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198
           +    ++ +S      +     +PP P       T G  R++V             ++ P
Sbjct: 329 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 367

Query: 199 PSYKPLFLDRGYTSA 213
              +  FL+R   +A
Sbjct: 368 DERRRKFLERNRAAA 382



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%)

Query: 78  PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126
           PPH        H H HP  H HP  HH    PH    +H H HP HH   PHPP      
Sbjct: 278 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 333

Query: 127 -----------PTHLSVPPRP 136
                      PT    PP+P
Sbjct: 334 AQVSPATQQMQPTQTIQPPQP 354



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 82  SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139
           SR +   H H H H H H  L   P  P+ H H HP HH  PHP P H    P   S+
Sbjct: 257 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 310



 Score = 32.7 bits (73), Expect = 0.35
 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%)

Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162
           H H+HPH H    PH P  H    P    +P Q     + P  +  + L A P
Sbjct: 266 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 317


>gi|59938772 cAMP responsive element binding protein 5 isoform gamma
           [Homo sapiens]
          Length = 475

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%)

Query: 79  PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138
           PH+ +   P H H +PH H HP  H  P   H   HPH H H+  H  P H    P P  
Sbjct: 245 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 302

Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198
           +    ++ +S      +     +PP P       T G  R++V             ++ P
Sbjct: 303 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 341

Query: 199 PSYKPLFLDRGYTSA 213
              +  FL+R   +A
Sbjct: 342 DERRRKFLERNRAAA 356



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%)

Query: 78  PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126
           PPH        H H HP  H HP  HH    PH    +H H HP HH   PHPP      
Sbjct: 252 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 307

Query: 127 -----------PTHLSVPPRP 136
                      PT    PP+P
Sbjct: 308 AQVSPATQQMQPTQTIQPPQP 328



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 82  SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139
           SR +   H H H H H H  L   P  P+ H H HP HH  PHP P H    P   S+
Sbjct: 231 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 284



 Score = 32.7 bits (73), Expect = 0.35
 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%)

Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162
           H H+HPH H    PH P  H    P    +P Q     + P  +  + L A P
Sbjct: 240 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 291


>gi|59938770 cAMP responsive element binding protein 5 isoform alpha
           [Homo sapiens]
          Length = 508

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%)

Query: 79  PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138
           PH+ +   P H H +PH H HP  H  P   H   HPH H H+  H  P H    P P  
Sbjct: 278 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 335

Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198
           +    ++ +S      +     +PP P       T G  R++V             ++ P
Sbjct: 336 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 374

Query: 199 PSYKPLFLDRGYTSA 213
              +  FL+R   +A
Sbjct: 375 DERRRKFLERNRAAA 389



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%)

Query: 78  PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126
           PPH        H H HP  H HP  HH    PH    +H H HP HH   PHPP      
Sbjct: 285 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 340

Query: 127 -----------PTHLSVPPRP 136
                      PT    PP+P
Sbjct: 341 AQVSPATQQMQPTQTIQPPQP 361



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 82  SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139
           SR +   H H H H H H  L   P  P+ H H HP HH  PHP P H    P   S+
Sbjct: 264 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 317



 Score = 32.7 bits (73), Expect = 0.35
 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%)

Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162
           H H+HPH H    PH P  H    P    +P Q     + P  +  + L A P
Sbjct: 273 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 324


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 35/200 (17%)

Query: 64  SLAGSPPGLAPPQP---------PPHRSRLEAPAH--AHSHPHVHVHPLLHHGPAQPHAH 112
           S+   P    PPQP         PP  + L  P H  A + PH H +P     P     +
Sbjct: 624 SMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDY 683

Query: 113 AHPHPHH--------HALPHP----PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMA 160
             PHP H        HA  HP    PPTHL+    P   P+        PP ++      
Sbjct: 684 VIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAP--IPQHL------PPTHQPISHHI 735

Query: 161 EPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLP--- 217
               P ++ L     + R  V      +      E+PPP    +  + G+   +H+P   
Sbjct: 736 PATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTM 795

Query: 218 -SAPRPAPPCPALCLQADRG 236
            S PR AP   A  L  + G
Sbjct: 796 SSHPRQAPERSAWELGIEAG 815



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 9/94 (9%)

Query: 58  PLELEGSLAGSPPGLAPP-QPPPHRSRLEAPAHAHSHPH-------VHVHPLLHHGPAQP 109
           P  L  + A  P  L P  QP  H     AP     HPH       V    ++ H P + 
Sbjct: 710 PTHLASTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQH-PTRA 768

Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQA 143
           H    PHPH     +    H+ VP    S+PRQA
Sbjct: 769 HERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQA 802



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 27/110 (24%)

Query: 56  LEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQ-PHAHA- 113
           ++ +E++       P  A  +PPPH  R+  P + H H H+HV   +   P Q P   A 
Sbjct: 751 MQRMEVQRRRMMQHPTRAHERPPPHPHRMH-PNYGHGH-HIHVPQTMSSHPRQAPERSAW 808

Query: 114 ------------------HPHPHHHALPHPPPT--HLSVPPRPWSYPRQA 143
                             HPH  H+   H PP   HL +   P   P  A
Sbjct: 809 ELGIEAGVTAATYTPGALHPHLAHY---HAPPRLHHLQLGALPLMVPDMA 855



 Score = 31.6 bits (70), Expect = 0.78
 Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 4/57 (7%)

Query: 89  HAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAES 145
           HA  HPH        HG    H H H H  H A+P  P    S P  P   P Q ++
Sbjct: 495 HALGHPHTSCFQ--QHGHHFQHHHHHHHTPHPAVPVSP--SFSDPACPVERPPQVQA 547



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 21/64 (32%), Positives = 23/64 (35%), Gaps = 9/64 (14%)

Query: 78  PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHA-----HAHPHPHHHALPHPPPTHLSV 132
           PP   RL  P+    H         HH    PH      H H   HHH   H P  H +V
Sbjct: 471 PPAMPRL--PSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTP--HPAV 526

Query: 133 PPRP 136
           P  P
Sbjct: 527 PVSP 530


>gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo
           sapiens]
          Length = 475

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 42/171 (24%), Positives = 55/171 (32%), Gaps = 30/171 (17%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLH-------HGPAQPHAHAHPHPHHHAL 122
           P + PP        +    H HS  H  +HP +H       H    P  H   HP  H  
Sbjct: 82  PSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPF 141

Query: 123 PHP---PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRK 179
            HP   PP HL + P     P       S  P     +  +  PP +      T    R 
Sbjct: 142 IHPPVHPPIHLHIHP-----PIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRP 196

Query: 180 IVTPFLSRRDSAEKQEQP---PPSYKPLFLDRGYTSALHLPSAPRPAPPCP 227
            V P      S      P   PP + P+        ++H  + P   PP P
Sbjct: 197 PVHP------STHPSTHPLIHPPIHPPIH------PSIHPSTHPPTHPPVP 235



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 7/69 (10%)

Query: 70  PGLAPP-QPPPHRSR---LEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHP 125
           P + PP  P  H S    +  P H  +HP  H  PL+H  P  P  H   HP  H   HP
Sbjct: 176 PSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTH--PLIHP-PIHPPIHPSIHPSTHPPTHP 232

Query: 126 PPTHLSVPP 134
           P  H S  P
Sbjct: 233 PVPHPSTHP 241


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 43/144 (29%), Positives = 48/144 (33%), Gaps = 49/144 (34%)

Query: 69  PPGLAPPQPPPHRSRLEA--------------PAHAHSHPHVH-----VHP------LLH 103
           PPG+ P  PPP      A              P H HSHPH        HP      L H
Sbjct: 254 PPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAH 313

Query: 104 HGPAQPHAHAHPHP------------HHHALPHPPPTHLSVPPR--PWSYPRQAESDM-- 147
           HG   PH   HPH                 +PHP P  + +PPR  P+  P      M  
Sbjct: 314 HG---PHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPP 370

Query: 148 ----SKPPCYEEAVLMAEP-PPPY 166
                 PP          P PPPY
Sbjct: 371 HGMRGPPPLMPPHGYTGPPRPPPY 394



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 24/74 (32%), Positives = 27/74 (36%), Gaps = 14/74 (18%)

Query: 69  PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPT 128
           PPG+  P PPP       P            P+ H GP  PH    P P        PP 
Sbjct: 338 PPGMPHPGPPPMGMPPRGPPFGS--------PMGHPGPMPPHGMRGPPPLM------PPH 383

Query: 129 HLSVPPRPWSYPRQ 142
             + PPRP  Y  Q
Sbjct: 384 GYTGPPRPPPYGYQ 397


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 24/86 (27%)

Query: 80  HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139
           H +   AP  A +HPH H HP             H H HHH  P PP   L +PP+P   
Sbjct: 640 HGASAGAPHSAQTHPHHHHHP-------------HHHHHHHHPPQPPSPLLLLPPQP-DE 685

Query: 140 PRQAESDMSKPPCYEEAVLMAEPPPP 165
           P       + PP          PPPP
Sbjct: 686 PGSERHHPAPPP----------PPPP 701



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 24/84 (28%)

Query: 60  ELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH---AHPH 116
           +L G+ AG+P      Q  PH          H HPH H H   HH P QP +      P 
Sbjct: 638 KLHGASAGAPHSA---QTHPHH---------HHHPHHHHH---HHHPPQPPSPLLLLPPQ 682

Query: 117 P------HHHALPHPPPTHLSVPP 134
           P       HH  P PPP     PP
Sbjct: 683 PDEPGSERHHPAPPPPPPPPPPPP 706



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 2/27 (7%)

Query: 65  LAGSPPGLAPPQPPPHRSRLEAPAHAH 91
           L G+PP   PP PPP  + L    HAH
Sbjct: 281 LLGAPP--PPPPPPPPLAELAGAPHAH 305


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 24/86 (27%)

Query: 80  HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139
           H +   AP  A +HPH H HP             H H HHH  P PP   L +PP+P   
Sbjct: 640 HGASAGAPHSAQTHPHHHHHP-------------HHHHHHHHPPQPPSPLLLLPPQP-DE 685

Query: 140 PRQAESDMSKPPCYEEAVLMAEPPPP 165
           P       + PP          PPPP
Sbjct: 686 PGSERHHPAPPP----------PPPP 701



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 24/84 (28%)

Query: 60  ELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH---AHPH 116
           +L G+ AG+P      Q  PH          H HPH H H   HH P QP +      P 
Sbjct: 638 KLHGASAGAPHSA---QTHPHH---------HHHPHHHHH---HHHPPQPPSPLLLLPPQ 682

Query: 117 P------HHHALPHPPPTHLSVPP 134
           P       HH  P PPP     PP
Sbjct: 683 PDEPGSERHHPAPPPPPPPPPPPP 706



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 2/27 (7%)

Query: 65  LAGSPPGLAPPQPPPHRSRLEAPAHAH 91
           L G+PP   PP PPP  + L    HAH
Sbjct: 281 LLGAPP--PPPPPPPPLAELAGAPHAH 305


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 24/86 (27%)

Query: 80  HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139
           H +   AP  A +HPH H HP             H H HHH  P PP   L +PP+P   
Sbjct: 640 HGASAGAPHSAQTHPHHHHHP-------------HHHHHHHHPPQPPSPLLLLPPQP-DE 685

Query: 140 PRQAESDMSKPPCYEEAVLMAEPPPP 165
           P       + PP          PPPP
Sbjct: 686 PGSERHHPAPPP----------PPPP 701



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 24/84 (28%)

Query: 60  ELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH---AHPH 116
           +L G+ AG+P      Q  PH          H HPH H H   HH P QP +      P 
Sbjct: 638 KLHGASAGAPHSA---QTHPHH---------HHHPHHHHH---HHHPPQPPSPLLLLPPQ 682

Query: 117 P------HHHALPHPPPTHLSVPP 134
           P       HH  P PPP     PP
Sbjct: 683 PDEPGSERHHPAPPPPPPPPPPPP 706



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 2/27 (7%)

Query: 65  LAGSPPGLAPPQPPPHRSRLEAPAHAH 91
           L G+PP   PP PPP  + L    HAH
Sbjct: 281 LLGAPP--PPPPPPPPLAELAGAPHAH 305


>gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo
           sapiens]
          Length = 217

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 41/160 (25%), Positives = 60/160 (37%), Gaps = 24/160 (15%)

Query: 70  PGLAPPQPPPHRSRLEAPAHAHSHP--HVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP 127
           P + P   PP  S +  P ++  HP  H H+HP +H     P  H H HP  H  P  P 
Sbjct: 23  PSIHPCIHPPTYSSIHPPTYSSIHPSVHPHIHPSIH-----PSTHPHIHPSIH--PSIPS 75

Query: 128 THLSVPP--RPWSYPR-QAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPF 184
            H S+ P  RP +Y      + +S  P    ++ +   P  +              + P 
Sbjct: 76  IHPSIHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHI------------FIHPS 123

Query: 185 LSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAP 224
           +     A       PS  PLF+      + H P  P+  P
Sbjct: 124 IHSSIHASTHPHIHPSIYPLFIHPSIHPSTHPPIHPQIHP 163



 Score = 36.6 bits (83), Expect = 0.024
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 2/49 (4%)

Query: 84  LEAPAHAHSHPHV--HVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHL 130
           + +  HA +HPH+   ++PL  H    P  H   HP  H   HP  T+L
Sbjct: 124 IHSSIHASTHPHIHPSIYPLFIHPSIHPSTHPPIHPQIHPSIHPLLTNL 172


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 47/169 (27%), Positives = 58/169 (34%), Gaps = 42/169 (24%)

Query: 69   PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP- 127
            PP   PP P PH   ++ P     H   HV   +H      H H+    HH   P PPP 
Sbjct: 1628 PPPPPPPAPGPHL--VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685

Query: 128  --THLSVPPRPWSYPRQAESD-----MSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180
               H   PP P +  +  ++       S PP          PPPP S VL          
Sbjct: 1686 PAPHHHPPPHPSTGLQGLQAQHQHVVNSAPP--------PPPPPPPSSVLASGH------ 1731

Query: 181  VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRP-APPCPA 228
                     SA+    PP    PLF           PS+  P  PP P+
Sbjct: 1732 ------HTTSAQALHHPPHQGPPLF-----------PSSAHPTVPPYPS 1763


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 47/169 (27%), Positives = 58/169 (34%), Gaps = 42/169 (24%)

Query: 69   PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP- 127
            PP   PP P PH   ++ P     H   HV   +H      H H+    HH   P PPP 
Sbjct: 1628 PPPPPPPAPGPHL--VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685

Query: 128  --THLSVPPRPWSYPRQAESD-----MSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180
               H   PP P +  +  ++       S PP          PPPP S VL          
Sbjct: 1686 PAPHHHPPPHPSTGLQGLQAQHQHVVNSAPP--------PPPPPPPSSVLASGH------ 1731

Query: 181  VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRP-APPCPA 228
                     SA+    PP    PLF           PS+  P  PP P+
Sbjct: 1732 ------HTTSAQALHHPPHQGPPLF-----------PSSAHPTVPPYPS 1763


>gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]
          Length = 809

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 35/107 (32%), Positives = 44/107 (41%), Gaps = 19/107 (17%)

Query: 59  LELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPH 118
           +E EGS A +  G          + L+AP H   H   H +PL      QP      HPH
Sbjct: 1   MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPL-----RQPQFRLL-HPH 54

Query: 119 HHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPP 165
           HH  P PPP+     P+P     Q +  +  PP      L   PPPP
Sbjct: 55  HHLPPPPPPS-----PQP-----QPQCPLQPPP---PPPLPPPPPPP 88


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 50/207 (24%), Positives = 66/207 (31%), Gaps = 53/207 (25%)

Query: 74  PPQPPPHRSRLEAPAHAHSHPHV----------------------HVHPLLH-------- 103
           PP PPP   +  APA   S P                           P+LH        
Sbjct: 778 PPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPP 837

Query: 104 HGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKP-------PCYEEA 156
           H P  P     PH + HA+  PP  H ++P +P     +A +   KP       P   + 
Sbjct: 838 HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQT 897

Query: 157 VLMAEPP-------------PPYSEVLTDTRGLY---RKIVTPFLSRRDSAEKQEQPPPS 200
            L+ +PP             PP   + +    LY    + V P      S + Q QPPP 
Sbjct: 898 PLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957

Query: 201 YKPLFLDRGYTSALHLPSAPRPAPPCP 227
             P             P  P P  P P
Sbjct: 958 LPPPPHPSVQQQLQQQPPPPPPPQPQP 984



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 54/187 (28%), Positives = 72/187 (38%), Gaps = 15/187 (8%)

Query: 79  PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLS---VPPR 135
           P   +   P       H H H  +   PA P     P P     P PPP        PP 
Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPA-PVPQQPPPPPQQPPPPPPPQQQQQPPPPPP 781

Query: 136 PWSYPRQAESDM--SKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEK 193
           P S P+QA   M  S PP     V + EP  P S  + D  G + + +   L + +    
Sbjct: 782 PPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGS--VFDPIGHFTQPIL-HLPQPELPPH 838

Query: 194 QEQPPPSYKPLFLDRGYT---SALH--LPSAP-RPAPPCPALCLQADRGRRVFPSWTDSE 247
             QPP    P  L++       ALH  LP  P RP+    AL  +  R   V P+ T + 
Sbjct: 839 LPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTP 898

Query: 248 LSSREPL 254
           L  + P+
Sbjct: 899 LLPQPPM 905



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 21/145 (14%)

Query: 61   LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHP--HVHVHPLLHHGPAQPHAHAHPHPH 118
            ++  L   PP   PPQP P       P   H  P   VH+ P+        H    P P 
Sbjct: 966  VQQQLQQQPPPPPPPQPQP------PPQQQHQPPPRPVHLQPM----QFSTHIQQPPPPQ 1015

Query: 119  HHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYR 178
                PHPPP     PP+P + P+Q       P  ++          PYS           
Sbjct: 1016 GQQPPHPPPGQQPPPPQP-AKPQQVIQHHHSPRHHKS--------DPYSTGHLREAPSPL 1066

Query: 179  KIVTPFLSRRDSAEKQEQPPPSYKP 203
             I +P +S+  S   Q  P  + +P
Sbjct: 1067 MIHSPQMSQFQSLTHQSPPQQNVQP 1091



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 25/102 (24%), Positives = 34/102 (33%), Gaps = 5/102 (4%)

Query: 106 PAQPHAHAHPHPHHHALPH---PPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162
           P  P   A PHP     P      P    VPP+P   P         PP      + + P
Sbjct: 213 PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP 272

Query: 163 P--PPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYK 202
           P      + +   +G+ RK  T   +  D   +    PP  K
Sbjct: 273 PIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPK 314


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 27/81 (33%), Positives = 31/81 (38%), Gaps = 7/81 (8%)

Query: 63   GSLAGSP------PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPH 116
            G L  SP      PG   P P    +  + P+   +        L H GP  P  H  PH
Sbjct: 943  GRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPH 1002

Query: 117  PHHHALPHPPPTHLSV-PPRP 136
             HHH  P P P H    PP P
Sbjct: 1003 HHHHHAPPPQPHHHHAHPPHP 1023



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 50/157 (31%), Positives = 61/157 (38%), Gaps = 14/157 (8%)

Query: 71   GLAPPQPPPHRS---RLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP 127
            G  PP P P  S   R  AP      P +HV  L +  P  P       P       PPP
Sbjct: 1463 GTEPPAPHPGVSKPWRSAAPEEPERLP-LHVRFLENCQPRAPVTSGRGPPSEDGPGVPPP 1521

Query: 128  T-HLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLS 186
            +   SVPP P S PR +E +           L+  PPP  S  + D   L+ + + P L 
Sbjct: 1522 SPRRSVPPSPTS-PRASEEN--------GLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLE 1572

Query: 187  RRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPA 223
              +S EK E P     P  L      A  LP  P PA
Sbjct: 1573 FSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPA 1609



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 21/87 (24%)

Query: 66   AGSPPGLAPPQPPPHR--SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHA---HPHPHHH 120
            A SP     P PP  R  SR ++  H+   P  H HP  HH     H HA    PH HH 
Sbjct: 964  ASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHH-----HHHAPPPQPHHHHA 1018

Query: 121  ALPHP-----------PPTHLSVPPRP 136
              PHP           PP  L++ P+P
Sbjct: 1019 HPPHPPEMETGGSPDDPPPRLALGPQP 1045



 Score = 36.2 bits (82), Expect = 0.032
 Identities = 34/123 (27%), Positives = 41/123 (33%), Gaps = 11/123 (8%)

Query: 53   ALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH 112
            AL      L+ S  G      PP+PP  R     P   H  PH H  P+L    A P   
Sbjct: 1356 ALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASP--- 1412

Query: 113  AHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAV------LMAEPPPPY 166
              P P    L +           P S P    S + + P     V      L  EPP P+
Sbjct: 1413 --PDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPH 1470

Query: 167  SEV 169
              V
Sbjct: 1471 PGV 1473


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 27/168 (16%)

Query: 69  PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPH-PHHHALPH--- 124
           PP   PP P   R+     + A   P     P + +GP+ P   + P  P  H   H   
Sbjct: 228 PPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKT 287

Query: 125 PPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPF 184
           P P     PP P S      S+   PP  +     A PPPP   +               
Sbjct: 288 PGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVI--------------- 332

Query: 185 LSRRDSAEKQEQPPPSYK-----PLFLDRGYTSALHLPSAPRPAPPCP 227
              R+ A     PPP Y+     P    +        P+ P P PP P
Sbjct: 333 ---RNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPP 377



 Score = 35.4 bits (80), Expect = 0.054
 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 22/100 (22%)

Query: 73  APPQPPPHRSR----LEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPT 128
           APP PPP R         P H+   P  +        P  P      HP     P PPP 
Sbjct: 176 APPPPPPGRRANAPPTPLPMHSSKAPAYN-----REKPLPPTPGQRLHPGREGPPAPPP- 229

Query: 129 HLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSE 168
            +  PP P +  R   S  S          +A PPPPY +
Sbjct: 230 -VKPPPSPVNI-RTGPSGQS----------LAPPPPPYRQ 257


>gi|12751477 forkhead box L2 [Homo sapiens]
          Length = 376

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 32/84 (38%), Positives = 34/84 (40%), Gaps = 20/84 (23%)

Query: 67  GSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPP 126
           G PP  APP PP            H HPH H H L  H  A P     P P HH    PP
Sbjct: 278 GGPPA-APPPPP------------HPHPHPHAHHL--HAAAAPP----PAPPHHGAAAPP 318

Query: 127 PTHLSVPPRPWSYPRQAESDMSKP 150
           P  LS P  P +    A +  S P
Sbjct: 319 PGQLS-PASPATAAPPAPAPTSAP 341


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 54/188 (28%), Positives = 65/188 (34%), Gaps = 31/188 (16%)

Query: 51  LRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH 110
           L +L + PLE + SLA  PP L  P           PA   + P  ++ P L   P Q  
Sbjct: 504 LSSLIMPPLETQSSLA--PPSLQTP-----------PASLTTPPLENL-PSLAPPPLQTA 549

Query: 111 AHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQ------AESDMSKPPCYEEAVLMAEPPP 164
           +     PH    P P P  L  PP P + P        A      PP      L   P P
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609

Query: 165 PYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP--PSYKPLFLDRGYTS---ALHLPSA 219
           P S + T        +  P L    S      PP  P   PL           A+HL  A
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPS------PPASPPLSPLATPSPQAPNALAVHLLQA 663

Query: 220 PRPAPPCP 227
           P   PP P
Sbjct: 664 PFSPPPSP 671



 Score = 36.2 bits (82), Expect = 0.032
 Identities = 35/117 (29%), Positives = 41/117 (35%), Gaps = 17/117 (14%)

Query: 56  LEPLELEGSLAGSPPGL-APPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAH 114
           L PL        SP G  A P PPP  +    PA     P     PL           A 
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP-----PL-----------AT 339

Query: 115 PHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLT 171
           P P     P  PP+  ++P  P + P QA   M+ PP      L   PP      LT
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396



 Score = 36.2 bits (82), Expect = 0.032
 Identities = 61/228 (26%), Positives = 73/228 (32%), Gaps = 36/228 (15%)

Query: 69  PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQ----PHAHAHPHPHHHALPH 124
           PP  APP   P       P    + P   V PLL   P Q    P A     P     P 
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787

Query: 125 PPPTHLSVPP------RPWSYPRQAESDMS--------------KPPCYEEAVLMAEPPP 164
            PP  L+ PP       P S+P QA    S               PP     +L   P P
Sbjct: 788 APPA-LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846

Query: 165 PYSEVL-----TDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSA 219
           P S  L       T G    +  P L+   +      PPPS  P     G   A H  SA
Sbjct: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904

Query: 220 PRPAPPCPALCLQADRGRRVFPSWTDSELSSREPLEHGAWRLPVSIPL 267
                         + G    P   D+EL++  P    AW    + PL
Sbjct: 905 TSTPEELRGYDSGPEGGAAASPP-PDAELAACHP---AAWSRGPAPPL 948



 Score = 33.5 bits (75), Expect = 0.21
 Identities = 48/185 (25%), Positives = 58/185 (31%), Gaps = 37/185 (20%)

Query: 54  LELEPLELEGSLAGSPP--GLAPPQPPPHRSR----LEAPAHAHSHPHVHVHPLLHHGPA 107
           L L PL+   S   SPP   LA P P    +     L+AP      P V         PA
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP---FSPPA 681

Query: 108 QPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAES---DMSKPPCYEEAVLMAEPPP 164
            P       P   A P      L VPP P + P  + S       PP      L   P P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 165 PYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLF----LDRGYTSALHLPSAP 220
           P S  ++ +                       PPP   PL     L    +    LP +P
Sbjct: 742 PASPPMSPS---------------------ATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780

Query: 221 RPAPP 225
              PP
Sbjct: 781 LAKPP 785



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 40/120 (33%), Positives = 47/120 (39%), Gaps = 16/120 (13%)

Query: 53  ALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQP--H 110
           +L   PL++  S   SPP      PPP     +AP    + P + V P     PA P   
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPP-----QAPPPL-AAPPLQVPP---SPPASPPMS 748

Query: 111 AHAHPHPHHHALPHPPPTHLSVPPR-PWSYPRQ--AESDMSKPPCYEEAVLMAEPPPPYS 167
             A P P    L   PP  L VPP  P S P    A+     PP      L A P PP S
Sbjct: 749 PSATPPPRVPPLLAAPP--LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 52/196 (26%), Positives = 69/196 (35%), Gaps = 28/196 (14%)

Query: 56  LEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH-AH 114
           + P+++  SL    P L  P  P   S L+A     S      H  L   P Q  A    
Sbjct: 386 IPPIQVPHSLTS--PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS 443

Query: 115 PHPHHHALPHPPPTH--LSVPPRPWSYPRQ-----AESDMSKPPCYEEAVLMAE-----P 162
           P       P  PP    LS+P  P   P Q     A S +S P        ++      P
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASP---PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500

Query: 163 PPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP----PSYKPLFLDRGYTSALHLPS 218
             P S ++         +  P L    ++     PP    PS  P  L    T++  L +
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPAS--LTTPPLENLPSLAPPPLQ---TASAPLTT 555

Query: 219 APRPAPPCPALC-LQA 233
                PPCPA C LQA
Sbjct: 556 PHLETPPCPAPCPLQA 571



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 45/185 (24%), Positives = 60/185 (32%), Gaps = 19/185 (10%)

Query: 58  PLELEGSLAGSPPGLAPPQPPPHRSR--LEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHP 115
           P     SL  SP    PPQ PP  +   L+ P    + P +   P     P    + + P
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA-PRRPPTPGPDTSVSGP 870

Query: 116 HPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEE--------AVLMAEPPPPYS 167
                  P PPP     P    S P  A    S     EE            A  PPP +
Sbjct: 871 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930

Query: 168 EVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKP--------LFLDRGYTSALHLPSA 219
           E+       + +   P L+ R +       PP+  P        ++   G  SA   P A
Sbjct: 931 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990

Query: 220 PRPAP 224
             P P
Sbjct: 991 LDPGP 995


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 27/70 (38%), Positives = 29/70 (41%), Gaps = 21/70 (30%)

Query: 77  PPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRP 136
           PPPH        H H H H H H   HH  AQP   +H  PHHH     P  HL      
Sbjct: 334 PPPH--------HHHHHHHHHHH---HHHRAQPPQQSHHPPHHHR----PQPHLG----- 373

Query: 137 WSYPRQAESD 146
            S+P    SD
Sbjct: 374 -SFPESCSSD 382


>gi|50345831 forkhead box J3 [Homo sapiens]
          Length = 622

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 25/67 (37%), Positives = 27/67 (40%), Gaps = 6/67 (8%)

Query: 74  PPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSV- 132
           P   PPHR     P H    PH   HP  H     PH   HP PH H   HP   H ++ 
Sbjct: 379 PSPHPPHRPH-GLPQHPQRSPHPAPHPQQHSQLQSPHPQ-HPSPHQHIQHHPNHQHQTLT 436

Query: 133 ---PPRP 136
              PP P
Sbjct: 437 HQAPPPP 443



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 20/87 (22%)

Query: 92  SHPHVHVHPLLH-----HG-PAQPHAHAHPHPH---HHALPHPPPTHLSVPPRPWSYPRQ 142
           SHP +H  P  H     HG P  P    HP PH   H  L  P P H    P P  +   
Sbjct: 371 SHPQMHTQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQH----PSPHQH--- 423

Query: 143 AESDMSKPPCYEEAVLMAEPPPPYSEV 169
               +   P ++   L  + PPP  +V
Sbjct: 424 ----IQHHPNHQHQTLTHQAPPPPQQV 446


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 49/180 (27%), Positives = 64/180 (35%), Gaps = 28/180 (15%)

Query: 67  GSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVH----PL------LHHGPAQPHAHAHPH 116
           G PP    P PPP       P H H  P +  +    P+      LH G         P 
Sbjct: 419 GPPPPWMQPPPPPMNQGPHPPGH-HGPPPMDQYLGSTPVGSGVYRLHQGKGMM-----PP 472

Query: 117 PHHHALPHPPPTHLSVPPRPWSYP----RQAESDMSKPPCYEEAVLMAEPPPPYSEVLTD 172
           P    +P PPP     PP P S P    +Q +     PP    ++  + P P      T 
Sbjct: 473 PPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTT 532

Query: 173 TRGLYRKIVTPFLSRRDSA-----EKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCP 227
           T       + P+  ++ +A       Q Q  P+  P  L  G    L  P AP P PP P
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVP--LPPGVQPPLP-PGAPPPPPPPP 589



 Score = 32.7 bits (73), Expect = 0.35
 Identities = 28/107 (26%), Positives = 36/107 (33%), Gaps = 20/107 (18%)

Query: 65  LAGSPPGLAPPQPPPHRSRLEAPAH---------AHSHPHVHVHPLLHHGPAQ-PHAHAH 114
           LA +P   AP   PP  S +              + S P+  +H     GP   PH+  H
Sbjct: 340 LASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPH 399

Query: 115 P----------HPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPP 151
           P          HP  H    PPP  +  PP P +           PP
Sbjct: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP 446


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,361,296
Number of Sequences: 37866
Number of extensions: 1122118
Number of successful extensions: 12256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 667
Number of HSP's that attempted gapping in prelim test: 7922
Number of HSP's gapped (non-prelim): 3164
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press