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Search of human proteins with 21361834
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361834 solute carrier family 22, member 17 isoform a [Homo
sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361834 solute carrier family 22, member 17 isoform a [Homo ... 1089 0.0
gi|63999576 solute carrier family 22, member 17 isoform b [Homo ... 1032 0.0
gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1... 270 2e-72
gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6... 266 3e-71
gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 261 1e-69
gi|48526516 solute carrier family 22, member 23 isoform b [Homo ... 213 4e-55
gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo sap... 175 1e-43
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 138 1e-32
gi|166064021 solute carrier family 22 (organic anion transporter... 129 5e-30
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 120 3e-27
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 119 7e-27
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 119 9e-27
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 117 2e-26
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 117 3e-26
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 116 5e-26
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 115 8e-26
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 115 1e-25
gi|42542386 solute carrier family 22 (organic anion/cation trans... 113 5e-25
gi|153791484 putative UST1-like organic anion transporter [Homo ... 110 3e-24
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 108 9e-24
gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 106 5e-23
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 105 1e-22
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 99 7e-21
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 99 7e-21
gi|31542327 solute carrier family 22, member 16 [Homo sapiens] 98 2e-20
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 97 3e-20
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 97 4e-20
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 97 5e-20
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 96 1e-19
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 85 1e-16
>gi|21361834 solute carrier family 22, member 17 isoform a [Homo
sapiens]
Length = 538
Score = 1089 bits (2816), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
Sbjct: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
Query: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
Sbjct: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
Query: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
Sbjct: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
Query: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
Sbjct: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
Query: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
Sbjct: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
Query: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
Sbjct: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
Query: 361 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL 420
RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
Sbjct: 361 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL 420
Query: 421 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 480
FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
Sbjct: 421 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 480
Query: 481 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 538
ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
Sbjct: 481 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 538
>gi|63999576 solute carrier family 22, member 17 isoform b [Homo
sapiens]
Length = 520
Score = 1032 bits (2669), Expect = 0.0
Identities = 519/538 (96%), Positives = 519/538 (96%), Gaps = 18/538 (3%)
Query: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
Sbjct: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
Query: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
Sbjct: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
Query: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
Sbjct: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
Query: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
Sbjct: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
Query: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
Sbjct: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
Query: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
Sbjct: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
Query: 361 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL 420
RFGRRGILLLSMTLTGIASLVLLGLWD LNEAAITTFSVLGL
Sbjct: 361 RFGRRGILLLSMTLTGIASLVLLGLWDY------------------LNEAAITTFSVLGL 402
Query: 421 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 480
FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
Sbjct: 403 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 462
Query: 481 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 538
ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
Sbjct: 463 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 520
>gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1
[Homo sapiens]
Length = 558
Score = 270 bits (691), Expect = 2e-72
Identities = 181/450 (40%), Positives = 243/450 (54%), Gaps = 25/450 (5%)
Query: 90 WDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAG 149
W+LVC GW+V LEQ+ +LG+ G + LG DRFGRR + + +L L G A A
Sbjct: 119 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAA 178
Query: 150 SSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALV 209
S ++ LR L G LAG L +YL RLELCDP RL ++ L V G L GLA +
Sbjct: 179 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAAL 238
Query: 210 SKDWRFLQRM-ITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERN--RPH 266
+DWR LQ + +L LF+G+P LF ES WL+ Q+ A+ +L AE + P
Sbjct: 239 VQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPG 298
Query: 267 GQMLGEEAQEALQDLEN-TCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCY 325
L E + +L + P S LL R W+N LILGF++ + IR +
Sbjct: 299 DSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASF 358
Query: 326 QPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGL 385
+ P+ FYL L +G A A VFL +T D GRR +LLL +TG+ASL+LL
Sbjct: 359 RRSLAPQVPT-FYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLL-- 415
Query: 386 WDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGR 445
AQ L + SVLGL +S+A + LS+L AAEV PT +RG
Sbjct: 416 ----------AGAQY------LPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGA 459
Query: 446 GLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVL 505
GLGL++ G LG +GP LH G FLQ VV A+ A+L +L ++LLPE++ + LP+ L
Sbjct: 460 GLGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSL 519
Query: 506 RDGELCRRPSLLRQPPPTRCDHVPLLATPN 535
+D + RR LLR P R DH+PLL N
Sbjct: 520 QDADRLRRSPLLRGRP--RQDHLPLLPPSN 547
>gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6
[Homo sapiens]
Length = 560
Score = 266 bits (681), Expect = 3e-71
Identities = 180/450 (40%), Positives = 242/450 (53%), Gaps = 25/450 (5%)
Query: 90 WDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAG 149
W+LVC GW+V LEQ+ +LG+ G + LG DRFGRR + + +L L G A A
Sbjct: 121 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAA 180
Query: 150 SSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALV 209
S ++ LR L G LAG L +YL RLELCDP RL ++ L V G L GLA +
Sbjct: 181 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAAL 240
Query: 210 SKDWRFLQRM-ITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERN--RPH 266
+DWR LQ + +L LF+G+P LF ES WL+ Q+ A+ +L AE + P
Sbjct: 241 VQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPG 300
Query: 267 GQMLGEEAQEALQDLEN-TCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCY 325
L E + +L + P S LL R W+N LILGF++ + IR +
Sbjct: 301 DSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASF 360
Query: 326 QPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGL 385
+ P+ FYL L +G A A VFL +T D GRR +LLL +TG+ASL+LL
Sbjct: 361 RRSLAPQVPT-FYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLL-- 417
Query: 386 WDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGR 445
AQ L + SVLGL +S+A + LS+L AAEV PT +RG
Sbjct: 418 ----------AGAQY------LPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGA 461
Query: 446 GLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVL 505
GLGL++ G LG +G LH G FLQ VV A+ A+L +L ++LLPE++ + LP+ L
Sbjct: 462 GLGLVLGAGFLGQAAGLLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSL 521
Query: 506 RDGELCRRPSLLRQPPPTRCDHVPLLATPN 535
+D + RR LLR P R DH+PLL N
Sbjct: 522 QDADRLRRSPLLRGRP--RQDHLPLLPPSN 549
>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
sapiens]
Length = 686
Score = 261 bits (667), Expect = 1e-69
Identities = 165/491 (33%), Positives = 249/491 (50%), Gaps = 43/491 (8%)
Query: 63 APPD-----FNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
+PPD N + WDY L N + +WDLVCD W+V + + ++G GYL
Sbjct: 187 SPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLI 246
Query: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
G AD GRR ++L ++ + G+ A + + T LRF GF LAG+ L +Y +R+
Sbjct: 247 TGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRI 306
Query: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
ELC P +R + + V + G FL GLA + +DW+ LQ +I P +L L Y W +F
Sbjct: 307 ELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY-W-SIFP 364
Query: 238 ESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG---EEAQEALQDLENTCPLPATSS 292
ES RWL+ +Q E A+ ++ ++NR P G + G E +E + + C
Sbjct: 365 ESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVC------- 417
Query: 293 FSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSP-----SDFYLCSLLASGT 347
++ RN+WKN+++L + + I HC+ G +FY +
Sbjct: 418 --IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASI 475
Query: 348 AALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWD-----CEHPIFPTVWAQQGN 402
A ++C+ + V V GRRG LLL M LT +ASL+ LGL + +HP
Sbjct: 476 ALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHP--------DSG 527
Query: 403 PNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGP 462
+ + + FS++G+F+S A LS AE+ PT +R GLGL++A G L+ P
Sbjct: 528 MSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAP 587
Query: 463 AQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPP 522
LH G FL H++ A C L+CI+ I+LLPE++ + LPE + +GE R LL P
Sbjct: 588 IIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLL----P 643
Query: 523 TRCDHVPLLAT 533
+ PLL T
Sbjct: 644 HKKGEQPLLLT 654
>gi|48526516 solute carrier family 22, member 23 isoform b [Homo
sapiens]
Length = 405
Score = 213 bits (542), Expect = 4e-55
Identities = 134/392 (34%), Positives = 201/392 (51%), Gaps = 38/392 (9%)
Query: 157 LRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFL 216
LRF GF LAG+ L +Y +R+ELC P +R + + V + G FL GLA + +DW+ L
Sbjct: 5 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVL 64
Query: 217 QRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG--- 271
Q +I P +L L Y W +F ES RWL+ +Q E A+ ++ ++NR P G + G
Sbjct: 65 QALIICPFLLMLLY-W-SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIP 122
Query: 272 EEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGG 331
E +E + + C ++ RN+WKN+++L + + I HC+ G
Sbjct: 123 ELEKELSRRPKKVC---------IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMG 173
Query: 332 GSPS-----DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLW 386
+FY + A ++C+ + V V GRRG LLL M LT +ASL+ LGL
Sbjct: 174 HEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLL 233
Query: 387 DC-----EHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 441
+ +HP + + + FS++G+F+S A LS AE+ PT
Sbjct: 234 NLIGKYSQHP--------DSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTV 285
Query: 442 VRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLL 501
+R GLGL++A G L+ P LH G FL H++ A C L+CI+ I+LLPE++ + L
Sbjct: 286 IRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNL 345
Query: 502 PEVLRDGELCRRPSLLRQPPPTRCDHVPLLAT 533
PE + +GE R LL P + PLL T
Sbjct: 346 PENISNGEHYTRQPLL----PHKKGEQPLLLT 373
>gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo
sapiens]
Length = 495
Score = 175 bits (443), Expect = 1e-43
Identities = 149/451 (33%), Positives = 201/451 (44%), Gaps = 90/451 (19%)
Query: 90 WDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAG 149
W+LVC GW+V LEQ+ +LG+ G + LG DRFGRR + + +L L G A A
Sbjct: 119 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAA 178
Query: 150 SSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALV 209
S ++ LR L G LAG L +YL RLELCDP RL ++ L V G L GLA +
Sbjct: 179 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAAL 238
Query: 210 SKDWRFLQRM-ITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERN--RPH 266
+DWR LQ + +L LF+G+P LF ES WL+ Q+ A+ +L AE + P
Sbjct: 239 VQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPG 298
Query: 267 GQMLGEEAQEALQDLEN-TCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCY 325
L E + +L + P S LL R W+N LILGF++ +
Sbjct: 299 DSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLV-------- 350
Query: 326 QPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGL 385
GGG ++ G L LG LL S ++ ++SL
Sbjct: 351 ----GGGIRANL-------PGWTVLFLSVLG-----------LLASRAVSALSSLFAA-- 386
Query: 386 WDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL-FSSQAAAILSTLLAAEVIPTTVRG 444
+FPTV G VLG F QAA +L T
Sbjct: 387 -----EVFPTVIRGAG------------LGLVLGAGFLGQAAGLLDT------------- 416
Query: 445 RGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEV 504
LH G FLQ VV A+ A+L +L ++LLPE++ + LP+
Sbjct: 417 ---------------------LHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQS 455
Query: 505 LRDGELCRRPSLLRQPPPTRCDHVPLLATPN 535
L+D + RR LLR P R DH+PLL N
Sbjct: 456 LQDADRLRRSPLLRGRP--RQDHLPLLPPSN 484
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 138 bits (347), Expect = 1e-32
Identities = 143/484 (29%), Positives = 209/484 (43%), Gaps = 55/484 (11%)
Query: 39 ASAALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGW 98
ASA A S A +A P+ S P C W Y + + ++DLVC W
Sbjct: 102 ASATSALSCADPLAAF--PNRSAPLVP----CRGGWRY---AQAHSTIVSEFDLVCVNAW 152
Query: 99 QVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALR 158
+ L Q + LGF +G LGY ADR+GR I LL+ VG GV A A + + R
Sbjct: 153 MLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFR 212
Query: 159 FLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQR 218
FL G G + Y++ E+ QR V + ++ G + G+A +W+ +Q
Sbjct: 213 FLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQL 272
Query: 219 MITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEAL 278
IT P LFL Y W + ES RWLI +++ ++A +LR +A+ N G+ L E
Sbjct: 273 AITLPSFLFLLYYW--VVPESPRWLITRKKGDKALQILRRIAKCN---GKYLSSNYSEI- 326
Query: 279 QDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQ------PVGGGG 332
T S+ SF L+ + K LIL F F + + YQ + GG
Sbjct: 327 -----TVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVV---YQGLVMRLGIIGGN 378
Query: 333 SPSDFYLCSLLASGTAAL-ACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHP 391
DF++ SG L + + +T++R GRR S + G+A LV L +
Sbjct: 379 LYIDFFI-----SGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPE---- 429
Query: 392 IFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIM 451
W + TT + LG A + L+ +E+ PTT+R G+ L
Sbjct: 430 --GIAWLR-------------TTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCS 474
Query: 452 ALGALGGLSGPAQRLHMGH-GAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGEL 510
L GG+ P + L ++ A +C +MLLPETK LPE + D E
Sbjct: 475 GLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEK 534
Query: 511 CRRP 514
P
Sbjct: 535 LGSP 538
>gi|166064021 solute carrier family 22 (organic anion transporter),
member 13 [Homo sapiens]
Length = 551
Score = 129 bits (325), Expect = 5e-30
Identities = 133/500 (26%), Positives = 212/500 (42%), Gaps = 53/500 (10%)
Query: 39 ASAALAASAASRVATSTDPSCSGFAPPDFNHCLKD---------------WDY--NGLPV 81
A+ L S A +P C F PP N L+D W+Y N LP
Sbjct: 64 AAEQLVLSVPLDTAGHPEP-CLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPS 122
Query: 82 LTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPC 141
L +++LVCD Q +F+ G G L G DR GR+ +L L L
Sbjct: 123 LKN----EFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLI 178
Query: 142 GVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHF 201
G+ A S MALRF + +AG+ + E P+ R + + + G
Sbjct: 179 GLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQM 238
Query: 202 LFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAE 261
+ GLA ++WR LQ TAP +L FY W ESARWL+ + +++EA +++ A
Sbjct: 239 VLAGLAYGFRNWRLLQITGTAPGLLLFFYFW--ALPESARWLLTRGRMDEAIQLIQKAAS 296
Query: 262 RNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAI 321
NR + L E L E T P S + L + + K LI+ F + ++
Sbjct: 297 VNR---RKLSPELMNQLVP-EKTGP-----SGNALDLFRHPQLRKVTLII-FCVWFVDSL 346
Query: 322 RHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLV 381
+ + G D YL L+ A + RFGR+ L ++ L G+ ++
Sbjct: 347 GYYGLSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCII 406
Query: 382 LLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 441
++ + + P+ +T +V+G ++ AA +S + +AE+ PT
Sbjct: 407 IIFI-PADLPV------------------VVTMLAVVGKMATAAAFTISYVYSAELFPTI 447
Query: 442 VRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLL 501
+R G+GL+ +GG+ P L + A L ++ + ++ L LLPET + L
Sbjct: 448 LRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGL 507
Query: 502 PEVLRDGELCRRPSLLRQPP 521
+ L+D EL P + P
Sbjct: 508 KDTLQDLELGPHPRSPKSVP 527
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 120 bits (301), Expect = 3e-27
Identities = 127/509 (24%), Positives = 208/509 (40%), Gaps = 44/509 (8%)
Query: 6 IFTLAPPLHCHYGAFPPNASG--WEQPPNASGVSVASAALAASAASRVATSTDPSCSGFA 63
IFT A P+H + P NAS W P +G + + T +
Sbjct: 39 IFTAATPVH--HCRPPHNASTGPWVLPMGPNGKPERCLRFVHPPNASLPNDTQRA----- 91
Query: 64 PPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPAD 123
CL W YN + + +WDLVC+ + Q +F+ G G L LG +D
Sbjct: 92 ---MEPCLDGWVYNSTK---DSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSD 145
Query: 124 RFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPT 183
RFGRR I+ + L+ G G A + + M RFL GF ++G+ L ++ +E
Sbjct: 146 RFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTR 205
Query: 184 QRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWL 243
R ++ A G F+ GLA WR+LQ ++ P +F W ES RWL
Sbjct: 206 MRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSW--WTPESIRWL 263
Query: 244 IVKRQIEEAQSVLRILAERN--RPHGQMLG-EEAQEALQDLENTCPLPATSSFSFASLLN 300
++ + +A +LR +A N + G+ L EE + LQ + T+S F +
Sbjct: 264 VLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPML 323
Query: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
R + L T F +++ + G + Y+ ++ G A +++
Sbjct: 324 RRMTFCLSLAWFATGFAYYSLAMGVEEFG-----VNLYILQIIFGGVDVPAKFITILSLS 378
Query: 361 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL 420
GR ++ L G A L L + P+ DL + T +V G
Sbjct: 379 YLGRHTTQAAALLLAGGAILALTFV-----PL-------------DL-QTVRTVLAVFGK 419
Query: 421 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 480
++ L +E+ PT +R G+G+ +G + P ++ F+ +++
Sbjct: 420 GCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYG 479
Query: 481 ACALLCILSIMLLPETKRKLLPEVLRDGE 509
ALL + + LPET + LPE + D E
Sbjct: 480 ITALLGGSAALFLPETLNQPLPETIEDLE 508
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 119 bits (298), Expect = 7e-27
Identities = 124/445 (27%), Positives = 194/445 (43%), Gaps = 41/445 (9%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ ++ + +++LVC W++ L Q GF G L +GY ADRFGR+
Sbjct: 121 CQDGWVYD---TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKL 177
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+L T+ + GV A + + ++ R L G + G + Y + E R VA
Sbjct: 178 CLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVA 237
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ ++ G GLA WR+LQ ++ P LFL Y W ES RWL+ +++
Sbjct: 238 IMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYW--CVPESPRWLLSQKRN 295
Query: 250 EEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKN-- 307
EA ++ +A++N G+ L+ L + S SFA L + K
Sbjct: 296 TEAIKIMDHIAQKN-------GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTF 348
Query: 308 -LLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRG 366
L+ L FT+ + + + G DF +L+ A +A +T+DR GR
Sbjct: 349 ILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIAL----ITIDRVGRIY 404
Query: 367 ILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAA 426
+ +S L G A LV++ + + DL+ I V G A
Sbjct: 405 PMAMSNLLAGAACLVMIFI------------------SPDLHWLNIIIMCV-GRMGITIA 445
Query: 427 AILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGP--AQRLHMGHGAFLQHVVLAACAL 484
+ L+ AE+ PT VR G+ + +L +GG+ P RL A L ++ A L
Sbjct: 446 IQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFRLREVWQA-LPLILFAVLGL 504
Query: 485 LCILSIMLLPETKRKLLPEVLRDGE 509
L +LLPETK LPE ++D E
Sbjct: 505 LAAGVTLLLPETKGVALPETMKDAE 529
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 119 bits (297), Expect = 9e-27
Identities = 123/460 (26%), Positives = 192/460 (41%), Gaps = 44/460 (9%)
Query: 70 CLKDWDYNGLPVLTTNAI-GQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRR 128
C + W+Y+ +T A QWDLVC+ F G G + GY +DRFGRR
Sbjct: 113 CSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRR 172
Query: 129 GIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRV 188
++L+ G+ AA+ S R L G LAG + V + LE D R
Sbjct: 173 RLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVA 232
Query: 189 ALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQ 248
+ GG L + + +DWR+L +T PC + W ESARWL+ +
Sbjct: 233 GVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLW--WVPESARWLLTQGH 290
Query: 249 IEEAQSVLRILAERNRPHGQMLGEE--AQEALQDL---ENTCPLPATSSFSFASLLNYRN 303
++EA R L R +G+ + E+ +QEA+ + E P+ L + +
Sbjct: 291 VKEAH---RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHIS 347
Query: 304 IWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ ++ G NF + + + G + Y LL + + + ++V G
Sbjct: 348 LCCVVVWFG-VNFSYYGL-----SLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAG 401
Query: 364 RR----GILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLG 419
RR G LL + G LV + W+ T +V+G
Sbjct: 402 RRLTQAGTLLGTALAFGTRLLVSSDM---------KSWS--------------TVLAVMG 438
Query: 420 LFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVL 479
S+AA + L +E+ PT +R G+GL +G LGG P L G L +
Sbjct: 439 KAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTY 498
Query: 480 AACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQ 519
ALL + +LLPET++ LPE ++D E P+ L++
Sbjct: 499 GGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQE 538
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 117 bits (294), Expect = 2e-26
Identities = 122/459 (26%), Positives = 192/459 (41%), Gaps = 44/459 (9%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C + W+Y+ +T A +WDLVC+ F G G + GY +DRFGRR
Sbjct: 113 CSQGWEYDHSEFSSTIAT-EWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRR 171
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
++L+ G+ AA+ S R L G LAG + V + LE D R
Sbjct: 172 LLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAG 231
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ GG L + + +DWR+L +T PC + W ESARWL+ + +
Sbjct: 232 VLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLW--WVPESARWLLTQGHV 289
Query: 250 EEAQSVLRILAERNRPHGQMLGEE--AQEALQDL---ENTCPLPATSSFSFASLLNYRNI 304
+EA R L R +G+ + E+ +QEA+ + E P+ L + ++
Sbjct: 290 KEAH---RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISL 346
Query: 305 WKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGR 364
++ G NF + + + G + Y LL + + + ++V GR
Sbjct: 347 CCVVVWFG-VNFSYYGL-----SLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGR 400
Query: 365 R----GILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL 420
R G LL + G LV + W+ T +V+G
Sbjct: 401 RLTQAGTLLGTALAFGTRLLVSSDM---------KSWS--------------TVLAVMGK 437
Query: 421 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 480
S+AA + L +E+ PT +R G+GL +G LGG P L G L +
Sbjct: 438 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYG 497
Query: 481 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQ 519
ALL + +LLPET++ LPE ++D E P+ L++
Sbjct: 498 GIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQE 536
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 117 bits (292), Expect = 3e-26
Identities = 125/474 (26%), Positives = 194/474 (40%), Gaps = 45/474 (9%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSS 423
RR + ++ L GI ++L G+ + I T+ +VLG
Sbjct: 394 RRPAQMAALLLAGIC-ILLNGVIPQDQSI------------------VRTSLAVLGKGCL 434
Query: 424 QAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGP----AQRLHMGHGAFLQHVVL 479
A+ L E+ PT +R G+G+ + +G + P L+ F+ V
Sbjct: 435 AASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVP 494
Query: 480 AACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLAT 533
A + + + LLPET + LP+ ++D E R+ RQ + VPL A+
Sbjct: 495 VAASAVTV----LLPETLGQPLPDTVQDLE-SRKGKQTRQQQEHQKYMVPLQAS 543
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 116 bits (291), Expect = 5e-26
Identities = 116/449 (25%), Positives = 192/449 (42%), Gaps = 39/449 (8%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y ++ + +++LVC W + L Q +GF G + +GY ADRFGR+
Sbjct: 122 CRDGWVYE---TPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKL 178
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+L T+ + GV A + + T ++ R + G + L Y++ E R V
Sbjct: 179 CLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVG 238
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ ++ G + G+A WR+LQ + P FL Y W ES RWLI + +
Sbjct: 239 IFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYW--CIPESPRWLISQNKN 296
Query: 250 EEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLL 309
EA +++ +A++N G+ +LQ L + SF L+ I K+ +
Sbjct: 297 AEAMRIIKHIAKKN-------GKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTM 349
Query: 310 IL---GFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRG 366
IL FT+ + + + + G DF+ +L+ A + + T+DR GRR
Sbjct: 350 ILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIIL----TIDRIGRRY 405
Query: 367 ILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAA 426
S + G A L + + DL I S LG A
Sbjct: 406 PWAASNMVAGAACLASVFI------------------PGDLQWLKII-ISCLGRMGITMA 446
Query: 427 AILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGH-GAFLQHVVLAACALL 485
+ L+ AE+ PT +R G+ + ++ +GG+ P + + L +V L+
Sbjct: 447 YEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLV 506
Query: 486 CILSIMLLPETKRKLLPEVLRDGELCRRP 514
++LLPETK K LPE + + E +RP
Sbjct: 507 AGGLVLLLPETKGKALPETIEEAENMQRP 535
>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
Length = 553
Score = 115 bits (289), Expect = 8e-26
Identities = 121/460 (26%), Positives = 192/460 (41%), Gaps = 44/460 (9%)
Query: 58 SCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
+ + ++ D C+ W Y+ + T+ + +W+LVCD + Q +++ G G
Sbjct: 104 TATSWSEADTEPCVDGWVYDR-SIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAA 162
Query: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
G +DRFGRR ++ + + G A A + RFLL F +AGV + + +
Sbjct: 163 CGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLM 222
Query: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
E R V L GH L +A +DW LQ +++ P L Y W
Sbjct: 223 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSW--WLA 280
Query: 238 ESARWLIVKRQIE-EAQSVLRILAERNRPHGQMLGEEAQEAL-----QDLENTCPLPATS 291
ESARWL+ +++ Q + R+ A + G + E L ++L P +
Sbjct: 281 ESARWLLTTGRLDWGLQELWRVAAINGK--GAVQDTLTPEVLLSAMREELSMGQPPASLG 338
Query: 292 SFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALA 351
+ L +R L F F + Q +G S+ +L +
Sbjct: 339 TLLRMPGLRFRTCISTLCWFAF-GFTFFGLALDLQALG-----SNIFLLQM--------- 383
Query: 352 CVFLGVTVDRFGRRGILLLSMTL----TGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDL 407
F+GV VD + G LLL L T ASL+L GL + + P
Sbjct: 384 --FIGV-VDIPAKMGALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMG--------- 431
Query: 408 NEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLH 467
A + +VLGL AA T+ ++E+ PT +R +GL G + GP RL
Sbjct: 432 --ALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLL 489
Query: 468 MGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRD 507
HG +L +V +L L+ +LLPET+ LP+ ++D
Sbjct: 490 GVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQD 529
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 115 bits (287), Expect = 1e-25
Identities = 118/450 (26%), Positives = 184/450 (40%), Gaps = 44/450 (9%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSS 423
RR + ++ L GI ++L G+ + I T+ +VLG
Sbjct: 394 RRPAQMAALLLAGIC-ILLNGVIPQDQSI------------------VRTSLAVLGKGCL 434
Query: 424 QAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGP----AQRLHMGHGAFLQHVVL 479
A+ L E+ PT +R G+G+ + +G + P L+ F+ V
Sbjct: 435 AASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVP 494
Query: 480 AACALLCILSIMLLPETKRKLLPEVLRDGE 509
A + + + LLPET + LP+ ++D E
Sbjct: 495 VAASAVTV----LLPETLGQPLPDTVQDLE 520
>gi|42542386 solute carrier family 22 (organic anion/cation
transporter), member 9 [Homo sapiens]
Length = 553
Score = 113 bits (282), Expect = 5e-25
Identities = 138/547 (25%), Positives = 225/547 (41%), Gaps = 87/547 (15%)
Query: 6 IFTLAPPLHC---HYGAFPPNASGWEQPPNASGVSVA-SAALAASAASRVATSTDPS--- 58
IF +A LH ++ AF P W + VS + AL+ A R++ D +
Sbjct: 26 IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTGALSQDALLRISIPLDSNMRP 85
Query: 59 --CSGFAPP-----------------DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQ 99
C F P D C+ W Y+ + +T + +WDLVCD
Sbjct: 86 EKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSST-IVTEWDLVCDSQSL 144
Query: 100 VILEQILFILGFASGYLFLGYPADRFGRRGIV---LLTLGLVGPCGVGGAAAGSSTGVMA 156
+ + +F+ G G + G+ +DRFGRR ++ L + +VG C A A + +
Sbjct: 145 TSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCA---ALAPTFLIYCS 201
Query: 157 LRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGV---GGHFLFL-GLALVSKD 212
LRFL G + ++ E T R + G +G+ G F+ L GLA +D
Sbjct: 202 LRFLSGIAAMSLITNTIMLIAEWA--THRFQAM--GITLGMCPSGIAFMTLAGLAFAIRD 257
Query: 213 WRFLQRMITAPC-ILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHG---- 267
W LQ +++ P ++FL W LESARWLI+ + EE LR A R+
Sbjct: 258 WHILQLVVSVPYFVIFLTSSW---LLESARWLIINNKPEEGLKELRKAAHRSGMKNARDT 314
Query: 268 ---QMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFT---NFIAH-A 320
++L ++ L+ + P S +L+ NI K + +L FT NF+A+
Sbjct: 315 LTLEILKSTMKKELEAAQKKKP-------SLCEMLHMPNICKRISLLSFTRFANFMAYFG 367
Query: 321 IRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASL 380
+ Q +G ++ +L L LA + RR +L M L I L
Sbjct: 368 LNLHVQHLG-----NNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAICLL 422
Query: 381 VLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPT 440
++ + Q+ R++ + LGL +S A L+ EVIPT
Sbjct: 423 AIIFV------------PQEMQTLREV-------LATLGLGASALANTLAFAHGNEVIPT 463
Query: 441 TVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKL 500
+R R +G+ + G P + + L ++ + + +LLPET+ K
Sbjct: 464 IIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKP 523
Query: 501 LPEVLRD 507
L + ++D
Sbjct: 524 LFDTIQD 530
>gi|153791484 putative UST1-like organic anion transporter [Homo
sapiens]
Length = 547
Score = 110 bits (275), Expect = 3e-24
Identities = 121/452 (26%), Positives = 185/452 (40%), Gaps = 38/452 (8%)
Query: 65 PDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADR 124
PD C+ W Y+ +T + +WDLVC+ + + LF+ G G G+ +DR
Sbjct: 111 PDTEPCVDGWVYDQSSFPST-IVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDR 169
Query: 125 FGRRGIV---LLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCD 181
FGR+ ++ L L +VG C A A + +LRFL G + + L+ +E
Sbjct: 170 FGRKFVLRWSYLQLAIVGTCA---AFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWIT 226
Query: 182 PTQRLRVALAGELVGVG-GHFLFLGLALVSKDWRFLQRMITAPC-ILFLFYGWPGLFLES 239
Q +AL L GH LA V +D LQ +++APC + FLF W ES
Sbjct: 227 H-QFCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRW---LAES 282
Query: 240 ARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEE--AQEALQDLENTCPLPATSSFSFAS 297
ARWLI+ + EE LR A RN G E+ E L+ A S
Sbjct: 283 ARWLIINNKPEEGLKELRKAAHRN---GMKNAEDILTMEVLKSTMKQELEAAQKKHSLCE 339
Query: 298 LLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGV 357
LL NI K + L F F A I + ++ +L L LA
Sbjct: 340 LLRIPNICKRICFLSFVRF-ASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPW 398
Query: 358 TVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSV 417
++ RR +L M L L ++ + Q+ R +
Sbjct: 399 ALNHMSRRLSQMLLMFLLATCLLAIIFV------------PQEMQTLR-------VVLAT 439
Query: 418 LGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHV 477
LG+ ++ ST E+IP+ +RGR G+ +GG + + L +
Sbjct: 440 LGVGAASLGITCSTAQENELIPSIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWI 499
Query: 478 VLAACALLCILSIMLLPETKRKLLPEVLRDGE 509
+ A+L L ++LLPET+ + L + ++D E
Sbjct: 500 IYGVFAILSGLVVLLLPETRNQPLLDSIQDVE 531
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 108 bits (271), Expect = 9e-24
Identities = 110/442 (24%), Positives = 180/442 (40%), Gaps = 36/442 (8%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W YN V + + +WDLVC+ L Q +++ G G G ADR G +G
Sbjct: 107 CKDGWVYNR-SVFPSTIVMEWDLVCEARTLRDLAQSVYMAGVLVGAAVFGSLADRLGCKG 165
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
++ + + G A S + RFL+G +G+ L + +E R
Sbjct: 166 PLVWSYLQLAASGAATAYFSSFSAYCVFRFLMGMTFSGIILNSVSLVVEWMPTRGR---T 222
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
+AG L+G G + G+A + + WR LQ I+AP ++F Y W ES+RWL++
Sbjct: 223 VAGILLGYSFTLGQLILAGVAYLIRPWRCLQFAISAPFLIFFLYSW--WLPESSRWLLLH 280
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+ + A L+ +A N + G+ L +E + E + S R +
Sbjct: 281 GKSQLAVQNLQKVAAMNGRKEEGERLTKEVMSSYIQSEFASVCTSNSILDLFRTPAIRKV 340
Query: 305 WKNLLILGFTNFIA-HAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
L+++ F+N +A + + Q G YL L A + T+ G
Sbjct: 341 TCCLMVIWFSNSVAYYGLAMDLQKFG-----LSLYLVQALFGIINTPAMLVATATMIYVG 395
Query: 364 RRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSS 423
RR T + L+L GL + ++ +G + T + LG
Sbjct: 396 RRA--------TVASFLILAGLM-----VIANMFVPEG------TQILCTAQAALGKGCL 436
Query: 424 QAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACA 483
++ I L E+ PT +R G+G LGGL+ P + L V A A
Sbjct: 437 ASSFICVYLFTGELYPTEIRQMGMGFASVHARLGGLTAPLVTTLGEYSTILPPVSFGATA 496
Query: 484 LLCILSIMLLPETKRKLLPEVL 505
+L L++ +L ET+ L E +
Sbjct: 497 ILAGLAVCVLTETRNMPLVETI 518
>gi|211059435 solute carrier family 22, member 24 [Homo sapiens]
Length = 551
Score = 106 bits (265), Expect = 5e-23
Identities = 121/455 (26%), Positives = 182/455 (40%), Gaps = 44/455 (9%)
Query: 65 PDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADR 124
PD C+ W Y+ L+T + +WDLVC+ + Q LF+ G G L G+ +DR
Sbjct: 111 PDTEPCVDGWVYDRSSFLST-IVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDR 169
Query: 125 FGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQ 184
GR+ I L + A A + LRFL GF + +++ LE P
Sbjct: 170 VGRKIICKLCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRS 229
Query: 185 RLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLI 244
R + G L GLA +DW LQ ++ P I+ W +ESARWLI
Sbjct: 230 RSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWK--MVESARWLI 287
Query: 245 VKRQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYR 302
+ Q++E LR +A N + + L E + E TS FS +R
Sbjct: 288 INNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSL-----FR 342
Query: 303 NIWKNLLILGFTNFIAHAIRHCYQPVGG--------GGSPSDFYLCSLLASGTAALACVF 354
+ + G F+ AI P G G + S F + L + T CV
Sbjct: 343 APKLRMRVFGLC-FVRFAIT---VPFYGLILNLQHLGSNVSLFQI--LCGAVTFTARCVS 396
Query: 355 LGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITT 414
L +T++ GRR +L G+ LV T Q+ R
Sbjct: 397 L-LTLNHMGRRISQILFTFPVGLFILV------------NTFLPQEMQILR-------VV 436
Query: 415 FSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFL 474
+ LG+ S AA+ +++ E++PT +R G+ G G P M + L
Sbjct: 437 LATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTGAALAPLLMTLMAYSPHL 496
Query: 475 QHVVLAACALLCILSIMLLPETKRKLLPEVLRDGE 509
+ +L + I+LLPET+ LP ++D E
Sbjct: 497 PWISYGVFPILAVPVILLLPETRDLPLPNTIQDVE 531
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 105 bits (261), Expect = 1e-22
Identities = 114/450 (25%), Positives = 182/450 (40%), Gaps = 36/450 (8%)
Query: 66 DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRF 125
D C+ W Y+ + + +WDLVCD + Q L + G G + G+ +DRF
Sbjct: 112 DTEPCVDGWVYDQ-SYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRF 170
Query: 126 GRRGIV---LLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDP 182
GRR I+ LL L + C A A + LRFL GF + L E P
Sbjct: 171 GRRFILRWCLLQLAITDTCA---AFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRP 227
Query: 183 TQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPC-ILFLFYGWPGLFLESAR 241
+ V + G + GLA V +DW+ L + + P + FL W +ESAR
Sbjct: 228 NSKALVVILSSGALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRW---LVESAR 284
Query: 242 WLIVKRQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLL 299
WLI+ +++E LR +A N + + L E + E A + + L
Sbjct: 285 WLIITNKLDEGLKALRKVARTNGIKNAEETLNIEVVRSTMQEELDA---AQTKTTVCDLF 341
Query: 300 NYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTV 359
++ K + IL F F A+ I V S+ +L +L A + +T+
Sbjct: 342 RNPSMRKRICILVFLRF-ANTIPFYGTMVNLQHVGSNIFLLQVLYGAVALIVRCLALLTL 400
Query: 360 DRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLG 419
+ GRR +L M L G++ L + P +++ + + LG
Sbjct: 401 NHMGRRISQILFMFLVGLSILA--------NTFVP----------KEMQTLRVA-LACLG 441
Query: 420 LFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVL 479
+ S A + E+IPT +R R G+ + +G P L ++
Sbjct: 442 IGCSAATFSSVAVHFIELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWIIY 501
Query: 480 AACALLCILSIMLLPETKRKLLPEVLRDGE 509
++ L + LLPETK LP+ ++D E
Sbjct: 502 GIFPIIGGLIVFLLPETKNLPLPDTIKDVE 531
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 99.4 bits (246), Expect = 7e-21
Identities = 89/318 (27%), Positives = 133/318 (41%), Gaps = 17/318 (5%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLV 381
RR + ++ L GI L+
Sbjct: 394 RRPAQMAALLLAGICILL 411
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 99.4 bits (246), Expect = 7e-21
Identities = 89/318 (27%), Positives = 133/318 (41%), Gaps = 17/318 (5%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLV 381
RR + ++ L GI L+
Sbjct: 394 RRPAQMAALLLAGICILL 411
>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
Length = 577
Score = 98.2 bits (243), Expect = 2e-20
Identities = 103/426 (24%), Positives = 174/426 (40%), Gaps = 39/426 (9%)
Query: 84 TNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGV 143
+ A+ QW+LVCD W +L Q LF+ G G + GY +DR GRR ++ T + G+
Sbjct: 138 STAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGI 197
Query: 144 GGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLF 203
A A MA RF L + +G + ++ +E R ++ G L
Sbjct: 198 AAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLV 257
Query: 204 LGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERN 263
+ + W Q +++ + F+ W + E+ WL+ + + EEAQ ++ I+A+ N
Sbjct: 258 ALTGYLVRTWWLYQMILSTVTVPFILCCW--VLPETPFWLLSEGRYEEAQKIVDIMAKWN 315
Query: 264 RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLI--------LGFTN 315
R L E LQ + P N+ + L + LGF +
Sbjct: 316 RASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYS 375
Query: 316 FIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLT 375
F +++ +GG + YL L A F+ + +D+ GRR +L S+ +
Sbjct: 376 FSLNSVN-----LGG-----NEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCS 425
Query: 376 GIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAA 435
+A V++ + P + +T +++G F+ AA L L A
Sbjct: 426 ALACGVVMVI-----------------PQKHYILGVVT--AMVGKFAIGAAFGLIYLYTA 466
Query: 436 EVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPE 495
E+ PT VR +G + L + P F+ + + ALL + + LPE
Sbjct: 467 ELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPE 526
Query: 496 TKRKLL 501
T K L
Sbjct: 527 TLGKRL 532
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 97.4 bits (241), Expect = 3e-20
Identities = 109/460 (23%), Positives = 186/460 (40%), Gaps = 40/460 (8%)
Query: 58 SCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
+ + ++ D C+ W Y+ V T+ + +WDLVC L Q +F+ G G
Sbjct: 101 TATSWSEADTEPCVDGWVYDR-SVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFI 159
Query: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
G + RFGR+ ++ + G A + LRF+ F +AG+ L + +
Sbjct: 160 WGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMV 219
Query: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
E ++R G GLA +DWR LQ + P W
Sbjct: 220 EWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISW--WLP 277
Query: 238 ESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFAS 297
ESARWLI+K + ++A LR +A N E ++ L ++ S+ S
Sbjct: 278 ESARWLIIKGKPDQALQELRKVARINGHK-----EAKNLTIEVLMSSVKEEVASAKEPRS 332
Query: 298 LLNYRNI----WKN--LLILGFTNFIA-HAIRHCYQPVGGGGSPSDFYLCSLLASGTAAL 350
+L+ + W++ +L++ F+ I+ + + Q +G D +L L L
Sbjct: 333 VLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLG-----RDIFLLQALFGAVDFL 387
Query: 351 ACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEA 410
+ + GRR I S + G+A L + + P +DL
Sbjct: 388 GRATTALLLSFLGRRTIQAGSQAMAGLAILA--------NMLVP----------QDLQTL 429
Query: 411 AITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGH 470
+ F+VLG + T+ AE+ PT VR G++ +G LG + GP +
Sbjct: 430 RV-VFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQA 488
Query: 471 GAFLQHVVLAACALLCILSIM-LLPETKRKLLPEVLRDGE 509
L ++ ++ L ++ LPET+ LP+ ++D E
Sbjct: 489 LPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE 528
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 97.1 bits (240), Expect = 4e-20
Identities = 88/317 (27%), Positives = 142/317 (44%), Gaps = 19/317 (5%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ ++ + +++LVC W++ L Q GF G L +GY ADRFGR+
Sbjct: 121 CQDGWVYD---TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKL 177
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+L T+ + GV A + + ++ R L G + G + Y + E R VA
Sbjct: 178 CLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVA 237
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ ++ G GLA WR+LQ ++ P LFL Y W ES RWL+ +++
Sbjct: 238 IMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYW--CVPESPRWLLSQKRN 295
Query: 250 EEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKN-- 307
EA ++ +A++N G+ L+ L + S SFA L + K
Sbjct: 296 TEAIKIMDHIAQKN-------GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTF 348
Query: 308 -LLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRG 366
L+ L FT+ + + + G DF +L+ A +A +T+DR GR
Sbjct: 349 ILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIAL----ITIDRVGRIY 404
Query: 367 ILLLSMTLTGIASLVLL 383
+ +S L G A LV++
Sbjct: 405 PMAMSNLLAGAACLVMI 421
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 96.7 bits (239), Expect = 5e-20
Identities = 110/470 (23%), Positives = 198/470 (42%), Gaps = 47/470 (10%)
Query: 50 RVATSTDPSCSGFAPP--------DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVI 101
R+AT + S G P + CL W+++ L+T + +W+LVC+ W+
Sbjct: 85 RLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLST-IVTEWNLVCEDDWKAP 143
Query: 102 LEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLL 161
L LF +G G G +DRFGR+ ++ +T+G+ G S M F++
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGM--QTGFSFLQIFSKNFEM---FVV 198
Query: 162 GFLLAGVD-----LGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGL-ALVSKDWRF 215
F+L G+ + +++ E+ + R+ + G + ++ L L A +DWR
Sbjct: 199 LFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRM 258
Query: 216 LQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQ 275
L +T P +L + W ES RWLI + + EEA+ ++R A+ N +
Sbjct: 259 LLVALTMPGVLCVALWW--FIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPS 316
Query: 276 EALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPS 335
E LQDL + S + LL NI + + I+ ++ ++ + +
Sbjct: 317 E-LQDLSS----KKQQSHNILDLLRTWNI-RMVTIMSIMLWMTISVGYFGLSLDTPNLHG 370
Query: 336 DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPT 395
D ++ L++ A V + + RR + ++ L G L + + P
Sbjct: 371 DIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFM--------QLVPP 422
Query: 396 VWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGA 455
DL A T ++G F AA + + AE+ PT VR G+G+
Sbjct: 423 ----------DLYYLA-TVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASR 471
Query: 456 LGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVL 505
LG + P + FL ++++ + +L + + LPE+ LP+ +
Sbjct: 472 LGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTI 521
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 95.5 bits (236), Expect = 1e-19
Identities = 111/437 (25%), Positives = 179/437 (40%), Gaps = 49/437 (11%)
Query: 84 TNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGV 143
T+ +W L+ + ++V F G G + G +DRFGR+ + L L +
Sbjct: 95 TSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAI 154
Query: 144 GGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLF 203
+ S RFL+G + G+ L +++ L C T ALAG +GG F
Sbjct: 155 ANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVL-LNECVGTAYW--ALAG---SIGGLFFA 208
Query: 204 LGLALVS------KDWRFLQRMITAP-CILFLFYGWPGLFL-ESARWLIVKRQIEEAQSV 255
+G+A + + WR L ++ ++FL LF+ ES RWL + ++ EA+
Sbjct: 209 VGIAQYALLGYFIRSWRTLAILVNLQGTVVFLL----SLFIPESPRWLYSQGRLSEAEEA 264
Query: 256 LRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTN 315
L ++A+RNR + L + + SF L YR + + LIL F
Sbjct: 265 LYLIAKRNR---------KLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIW 315
Query: 316 FIAHAIRHCYQPVGG--GGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMT 373
F+ + + G GGS S L + C++L + FGR+ L +
Sbjct: 316 FVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYL-INQKWFGRKRTLSAFLC 374
Query: 374 LTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAIT---TFSVLGLFSSQAAAILS 430
L G+A L+++ L + +D A+ + S+LG + AA +
Sbjct: 375 LGGLACLIVMFLPE----------------KKDTGVFAVVNSHSLSLLGKLTISAAFNIV 418
Query: 431 TLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSI 490
+ +E+ PT +R GLG +GG+ P L +V A L L
Sbjct: 419 YIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLS 478
Query: 491 MLLPETKRKLLPEVLRD 507
+LLPET L E D
Sbjct: 479 LLLPETLNSPLLETFSD 495
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 85.1 bits (209), Expect = 1e-16
Identities = 102/470 (21%), Positives = 190/470 (40%), Gaps = 49/470 (10%)
Query: 50 RVATSTDPSCSGFAPP--------DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVI 101
R+AT + S G P + CL W+++ L+T + +W+LVC+ W+V
Sbjct: 85 RLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLST-VVTEWNLVCEDNWKVP 143
Query: 102 LEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLL 161
L LF +G G G +DRFGR+ ++ T+ + G S + M F +
Sbjct: 144 LTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAV--QTGFSFLQIFSISWEM---FTV 198
Query: 162 GFLLAGVD-----LGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGL-ALVSKDWRF 215
F++ G+ + +++ E+ + R+ + G ++ L L A +DWR
Sbjct: 199 LFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRM 258
Query: 216 LQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQ 275
L +T P +L + W ES RWLI +R+ EA+ +++ A+ N + ++
Sbjct: 259 LLLALTVPGVLCVPLWW--FIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSV 316
Query: 276 EALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPS 335
E L PL +F L RNI + I+ ++ ++ + +
Sbjct: 317 EELN------PLKQQKAF-ILDLFRTRNI-AIMTIMSLLLWMLTSVGYFALSLDAPNLHG 368
Query: 336 DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPT 395
D YL L++ A + + + RR ++ ++ G L+ + L ++
Sbjct: 369 DAYLNCFLSALIEIPAYITAWLLLRTLPRR-YIIAAVLFWGGGVLLFIQLVPVDYYFLS- 426
Query: 396 VWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGA 455
+LG F +A + + AE+ PT VR +G+
Sbjct: 427 -----------------IGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASR 469
Query: 456 LGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVL 505
+G + P + L ++V+ + +L + + PE+ LPE L
Sbjct: 470 VGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETL 519
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.142 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,852,600
Number of Sequences: 37866
Number of extensions: 980650
Number of successful extensions: 3967
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3778
Number of HSP's gapped (non-prelim): 106
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.