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Search of human proteins with 21361759
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361759 myotubularin related protein 8 [Homo sapiens]
(704 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361759 myotubularin related protein 8 [Homo sapiens] 1439 0.0
gi|225543474 myotubularin related protein 7 [Homo sapiens] 717 0.0
gi|134142348 myotubularin related protein 6 [Homo sapiens] 714 0.0
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 377 e-104
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 377 e-104
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 377 e-104
gi|4557896 myotubularin [Homo sapiens] 358 7e-99
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 358 1e-98
gi|19923424 myotubularin related protein 9 [Homo sapiens] 320 4e-87
gi|217272865 myotubularin related protein 4 [Homo sapiens] 294 2e-79
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 282 7e-76
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 282 7e-76
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 282 7e-76
gi|239735519 SET binding factor 1 [Homo sapiens] 139 7e-33
gi|124028527 myotubularin related protein 10 [Homo sapiens] 138 2e-32
gi|29788755 SET binding factor 2 [Homo sapiens] 129 1e-29
gi|94721263 myotubularin related protein 12 [Homo sapiens] 122 9e-28
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 108 2e-23
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 108 2e-23
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 39 0.013
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 39 0.013
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 36 0.14
gi|44889483 cerebellar degeneration-related protein 1, 34kDa [Ho... 35 0.24
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 34 0.41
gi|4506537 receptor-interacting serine-threonine kinase 2 [Homo ... 34 0.53
gi|11386161 alpha 2 type IX collagen [Homo sapiens] 34 0.53
gi|122937273 hypothetical protein LOC131149 [Homo sapiens] 34 0.53
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 33 0.90
gi|194097442 protein tyrosine phosphatase, receptor type, N poly... 33 0.90
gi|194097440 protein tyrosine phosphatase, receptor type, N poly... 33 0.90
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 1439 bits (3726), Expect = 0.0
Identities = 704/704 (100%), Positives = 704/704 (100%)
Query: 1 MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEK 60
MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEK
Sbjct: 1 MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEK 60
Query: 61 LPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSK 120
LPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSK
Sbjct: 61 LPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSK 120
Query: 121 EMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSS 180
EMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSS
Sbjct: 121 EMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSS 180
Query: 181 KFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVD 240
KFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVD
Sbjct: 181 KFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVD 240
Query: 241 TRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEF 300
TRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEF
Sbjct: 241 TRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEF 300
Query: 301 LSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFY 360
LSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFY
Sbjct: 301 LSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFY 360
Query: 361 RTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFN 420
RTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFN
Sbjct: 361 RTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFN 420
Query: 421 ENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTM 480
ENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTM
Sbjct: 421 ENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTM 480
Query: 481 YGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKV 540
YGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKV
Sbjct: 481 YGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKV 540
Query: 541 RDEPPEEICTCSQLGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQ 600
RDEPPEEICTCSQLGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQ
Sbjct: 541 RDEPPEEICTCSQLGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQ 600
Query: 601 VKSQGADLHHNCCEIVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDI 660
VKSQGADLHHNCCEIVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDI
Sbjct: 601 VKSQGADLHHNCCEIVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDI 660
Query: 661 SEATGISGNLGISEARGFSGDMGILGDTGISKASTKEADYSKHQ 704
SEATGISGNLGISEARGFSGDMGILGDTGISKASTKEADYSKHQ
Sbjct: 661 SEATGISGNLGISEARGFSGDMGILGDTGISKASTKEADYSKHQ 704
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 717 bits (1852), Expect = 0.0
Identities = 335/543 (61%), Positives = 426/543 (78%), Gaps = 4/543 (0%)
Query: 1 MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEK 60
M+HI PKVENV+LVDR KK A G LYLTATH+I+VE S RKETWI I+T+EK
Sbjct: 1 MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK 60
Query: 61 LPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSK 120
T+ GCPL +RCKNF++ ++ + CH+VYISL++L++P E+LY FS+NP K
Sbjct: 61 QATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDK 120
Query: 121 EMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSS 180
E RE GW LID ++ RMG+PN W ++D NR+Y +C +YP E+ VPKS T +VGSS
Sbjct: 121 EEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSS 180
Query: 181 KFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVD 240
KFRS+ R PVLSY YK+N+A+ICR SQPLSGF RC++DE +L+AI + NPGS F+YVVD
Sbjct: 181 KFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVD 240
Query: 241 TRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEF 300
TRPKLNAMANRAAGKGYENEDNY+NI+F+F+GIENIHVMR+SLQK+LEVCELK+P+MS+F
Sbjct: 241 TRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDF 300
Query: 301 LSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFY 360
L GLE+SGWLRHIKAIMDAGIFI KAV E ASVLVHCSDGWDRTAQVCSVAS+LLDP Y
Sbjct: 301 LWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHY 360
Query: 361 RTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFN 420
RT KG M+LIEK+WIS GHKF+ R G+LDGD KE+SP+ QF++C+WQLMEQFPCAFEFN
Sbjct: 361 RTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFN 420
Query: 421 ENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKG--F 478
E FL+ I H++SCQFGNFL N QK+R +L++ E+T+S+W L + + D+ NPL++
Sbjct: 421 ERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHS 480
Query: 479 TMYGVLNPSTVPYNI--QFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEK 536
G L+ T P N +FW GMYNRF+KG+QP+QS+ + L+ +K++ LE ++ LE+
Sbjct: 481 QTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEE 540
Query: 537 KLK 539
+L+
Sbjct: 541 RLE 543
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 714 bits (1844), Expect = 0.0
Identities = 334/543 (61%), Positives = 431/543 (79%), Gaps = 5/543 (0%)
Query: 1 MDHITVPKVENVKLVDRY-VSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVE 59
M+HI KVE VKL+DR+ S K G LYLTATHL+++++ +KETWI HHIA+VE
Sbjct: 1 MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSH---QKETWILHHHIASVE 57
Query: 60 KLPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSS 119
KL +T+ GCPL ++CKNFR HF++ + CH++Y SLL+LS+ A EDLYAFSYNPK +
Sbjct: 58 KLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQN 117
Query: 120 KEMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGS 179
R GW+LID ++ RMG+PN +W ++DANR+Y+IC TYP E+ VP+ + +VGS
Sbjct: 118 DSERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGS 177
Query: 180 SKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVV 239
SKFRSK R PVLSY +++ AAICRCSQPLSGF RC++DE LL+AIS+ NP +++MYV+
Sbjct: 178 SKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVM 237
Query: 240 DTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSE 299
DTRPKLNAMANRAAGKGYENEDNY+NIRF+F+GIENIHVMRSSLQKLLEV K ++++
Sbjct: 238 DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVND 297
Query: 300 FLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPF 359
F SGLESSGWLRHIKA+MDA IF+ KA+ VE ASVLVHCSDGWDRT+QVCS+ S+LLD +
Sbjct: 298 FYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSY 357
Query: 360 YRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEF 419
YRT KG M+LIEK+WIS GHKFS+RCG LDGD KEVSP+FTQFL+C+W L EQFP AFEF
Sbjct: 358 YRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEF 417
Query: 420 NENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFT 479
+E FLL+IH+H+ SCQFGNFLGNCQK+RE+L++ EKT+S+WPFL++ + + NPLY +
Sbjct: 418 SEAFLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSES 477
Query: 480 -MYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKL 538
+ VL P+TV +N +FW MY++FD+ L P+QS+ ++ + +Q LE D+ +LE K+
Sbjct: 478 HRFTVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKI 537
Query: 539 KVR 541
K R
Sbjct: 538 KQR 540
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 377 bits (969), Expect = e-104
Identities = 200/481 (41%), Positives = 294/481 (61%), Gaps = 20/481 (4%)
Query: 75 KNFRVAHFVLDSDLVCHEVYISLLKLSQPA---LPEDLYAFSYNPKSSKEMRESGWKLID 131
+N R AH ++ +L+K + P LP L+AF Y + E+GWKL D
Sbjct: 159 RNLRFAH--KPEGRTRRSIFENLMKYAFPVSNNLP--LFAFEYK----EVFPENGWKLYD 210
Query: 132 PISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVL 191
P+ ++ R GIPN +W IT N YE+C TYP +VVP ++ + + FRS+ R+PVL
Sbjct: 211 PLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVL 270
Query: 192 SYLYKENNAAICRCSQPLSGFY-TRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMAN 250
S+++ E+ A I RCSQP+ G R +DE L+AI +N S +++ D RP +NA+AN
Sbjct: 271 SWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVAN 330
Query: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSE--FLSGLESSG 308
+A G GYE+ED Y N F+ I NIHVMR SL+KL E+ P + E +LS LES+
Sbjct: 331 KAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTH 387
Query: 309 WLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMI 368
WL HIK I+ + I V+ K SV+VHCSDGWDRTAQ+ S+A ++LD +YRT +G +
Sbjct: 388 WLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEV 447
Query: 369 LIEKEWISMGHKFSQRCGHLDGDSKEV--SPIFTQFLDCIWQLMEQFPCAFEFNENFLLE 426
L+EKEW+S GH+F R GH D + + SP+F QF+DC+WQ+ QFP AFEFNE FL+
Sbjct: 448 LVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLIT 507
Query: 427 IHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNP 486
I DH++SC FG FL N ++ R + ++T S+W ++ + DF NPLY ++ + VL P
Sbjct: 508 ILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH-VLYP 566
Query: 487 STVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPE 546
+++ W G Y R++ ++P++ + E+ +RA L+ V EL++++ R
Sbjct: 567 VASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSS 626
Query: 547 E 547
E
Sbjct: 627 E 627
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 377 bits (969), Expect = e-104
Identities = 200/481 (41%), Positives = 294/481 (61%), Gaps = 20/481 (4%)
Query: 75 KNFRVAHFVLDSDLVCHEVYISLLKLSQPA---LPEDLYAFSYNPKSSKEMRESGWKLID 131
+N R AH ++ +L+K + P LP L+AF Y + E+GWKL D
Sbjct: 87 RNLRFAH--KPEGRTRRSIFENLMKYAFPVSNNLP--LFAFEYK----EVFPENGWKLYD 138
Query: 132 PISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVL 191
P+ ++ R GIPN +W IT N YE+C TYP +VVP ++ + + FRS+ R+PVL
Sbjct: 139 PLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVL 198
Query: 192 SYLYKENNAAICRCSQPLSGFY-TRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMAN 250
S+++ E+ A I RCSQP+ G R +DE L+AI +N S +++ D RP +NA+AN
Sbjct: 199 SWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVAN 258
Query: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSE--FLSGLESSG 308
+A G GYE+ED Y N F+ I NIHVMR SL+KL E+ P + E +LS LES+
Sbjct: 259 KAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTH 315
Query: 309 WLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMI 368
WL HIK I+ + I V+ K SV+VHCSDGWDRTAQ+ S+A ++LD +YRT +G +
Sbjct: 316 WLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEV 375
Query: 369 LIEKEWISMGHKFSQRCGHLDGDSKEV--SPIFTQFLDCIWQLMEQFPCAFEFNENFLLE 426
L+EKEW+S GH+F R GH D + + SP+F QF+DC+WQ+ QFP AFEFNE FL+
Sbjct: 376 LVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLIT 435
Query: 427 IHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNP 486
I DH++SC FG FL N ++ R + ++T S+W ++ + DF NPLY ++ + VL P
Sbjct: 436 ILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH-VLYP 494
Query: 487 STVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPE 546
+++ W G Y R++ ++P++ + E+ +RA L+ V EL++++ R
Sbjct: 495 VASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSS 554
Query: 547 E 547
E
Sbjct: 555 E 555
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 377 bits (969), Expect = e-104
Identities = 200/481 (41%), Positives = 294/481 (61%), Gaps = 20/481 (4%)
Query: 75 KNFRVAHFVLDSDLVCHEVYISLLKLSQPA---LPEDLYAFSYNPKSSKEMRESGWKLID 131
+N R AH ++ +L+K + P LP L+AF Y + E+GWKL D
Sbjct: 87 RNLRFAH--KPEGRTRRSIFENLMKYAFPVSNNLP--LFAFEYK----EVFPENGWKLYD 138
Query: 132 PISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVL 191
P+ ++ R GIPN +W IT N YE+C TYP +VVP ++ + + FRS+ R+PVL
Sbjct: 139 PLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVL 198
Query: 192 SYLYKENNAAICRCSQPLSGFY-TRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMAN 250
S+++ E+ A I RCSQP+ G R +DE L+AI +N S +++ D RP +NA+AN
Sbjct: 199 SWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVAN 258
Query: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSE--FLSGLESSG 308
+A G GYE+ED Y N F+ I NIHVMR SL+KL E+ P + E +LS LES+
Sbjct: 259 KAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTH 315
Query: 309 WLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMI 368
WL HIK I+ + I V+ K SV+VHCSDGWDRTAQ+ S+A ++LD +YRT +G +
Sbjct: 316 WLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEV 375
Query: 369 LIEKEWISMGHKFSQRCGHLDGDSKEV--SPIFTQFLDCIWQLMEQFPCAFEFNENFLLE 426
L+EKEW+S GH+F R GH D + + SP+F QF+DC+WQ+ QFP AFEFNE FL+
Sbjct: 376 LVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLIT 435
Query: 427 IHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNP 486
I DH++SC FG FL N ++ R + ++T S+W ++ + DF NPLY ++ + VL P
Sbjct: 436 ILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH-VLYP 494
Query: 487 STVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPE 546
+++ W G Y R++ ++P++ + E+ +RA L+ V EL++++ R
Sbjct: 495 VASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSS 554
Query: 547 E 547
E
Sbjct: 555 E 555
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 358 bits (920), Expect = 7e-99
Identities = 197/496 (39%), Positives = 285/496 (57%), Gaps = 11/496 (2%)
Query: 23 PANGILYLTATHLIYVEASGAARKETWIALHHIATVEKLP-ITSLG---CPLTLRCKNFR 78
P G +Y+T L + + L I+ +EK+ TS G L + CK+ R
Sbjct: 58 PIKGRVYITNYRLYLRSLETDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKDMR 117
Query: 79 VAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMRESGWKLIDPISDFGR 138
F L + +L L L F++ + ++ GW + +P+ ++ R
Sbjct: 118 NLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLFAF--LNEEKFNVDGWTVYNPVEEYRR 175
Query: 139 MGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKEN 198
G+PN +W IT N+ YE+C TYP +VVP + + + FRS+ R+PVLS+++ EN
Sbjct: 176 QGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPEN 235
Query: 199 NAAICRCSQPLSGFY-TRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGY 257
I RCSQPL G R DDE L+ I +TN + + D RP +NA+AN+A G GY
Sbjct: 236 KTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKATGGGY 295
Query: 258 ENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIM 317
E++D Y N F+ I NIHVMR SL+K+ ++ S +LS LES+ WL HIK ++
Sbjct: 296 ESDDAYHNAELFFLDIHNIHVMRESLKKVKDIVYPNVEE-SHWLSSLESTHWLEHIKLVL 354
Query: 318 DAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISM 377
I + V K+SVLVHCSDGWDRTAQ+ S+A ++LD FYR+ +G IL++KEWIS
Sbjct: 355 TGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISF 414
Query: 378 GHKFSQRCGHLDGDSKEV--SPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQ 435
GHKF+ R GH D + + SPIF QF+DC+WQ+ +QFP AFEFNE FL+ I DH++SC+
Sbjct: 415 GHKFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCR 474
Query: 436 FGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQF 495
FG FL NC+ RE +V E+T S+W + K F+NP Y + VL P +++
Sbjct: 475 FGTFLFNCESARERQKVTERTVSLWSLINSNKEKFKNPFYTK-EINRVLYPVASMRHLEL 533
Query: 496 WCGMYNRFDKGLQPKQ 511
W Y R++ ++ +Q
Sbjct: 534 WVNYYIRWNPRIKQQQ 549
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 358 bits (918), Expect = 1e-98
Identities = 199/505 (39%), Positives = 296/505 (58%), Gaps = 24/505 (4%)
Query: 50 IALHHIATVEKLPITSLG---CPLTLRCKNFRVAHFVLDSDLVCHEVYISLLK-LSQPAL 105
+ L I+ VEK+ S G C + + CK+ R + + + + + L++ A
Sbjct: 149 VPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQE---EQSKLGIFENLNKHAF 205
Query: 106 P----EDLYAFSYNPKSSKEMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTY 161
P + L+AFSY K +GWK+ DP+S++ R G+PN +W I+ N NYE C TY
Sbjct: 206 PLSNGQALFAFSYKEK----FPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTY 261
Query: 162 PPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYT-RCVDDE 220
P IVVP SV + + FR+K RVPVLS+++ E+ A I RCSQPL G RC +DE
Sbjct: 262 PAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDE 321
Query: 221 LLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMR 280
L+ I N S + + D R A N+ G GYE+E Y N F+ I NIHVMR
Sbjct: 322 KYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMR 381
Query: 281 SSLQKLLEVCELKTPTMSE--FLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHC 338
SL+KL E+ P++ E +LS ++ + WL +I+ ++ + I ++ K SV+VHC
Sbjct: 382 ESLRKLKEIVY---PSIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHC 438
Query: 339 SDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEV--S 396
SDGWDRTAQ+ S+A ++LD +YRT KG L+EKEWIS GH+F+ R GH + + + S
Sbjct: 439 SDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRS 498
Query: 397 PIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKT 456
PIF QF+DC+WQ+ QFP AFEFNE FL+ I DH++SC FG FL NC++ R VY KT
Sbjct: 499 PIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKT 558
Query: 457 HSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLES 516
S+W ++ + +F NP + + + VL P +++ W Y R++ ++P+ + ++
Sbjct: 559 ISLWSYINSQLDEFSNPFFVNYENH-VLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQN 617
Query: 517 LLEIKKQRAMLETDVHELEKKLKVR 541
L E+ RA L+ V L++++ R
Sbjct: 618 LKELLAVRAELQKRVEGLQREVATR 642
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 320 bits (819), Expect = 4e-87
Identities = 187/541 (34%), Positives = 289/541 (53%), Gaps = 17/541 (3%)
Query: 4 ITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEKLPI 63
I P+V+NV L + G L LT HLI + + +E W+ +I ++K +
Sbjct: 7 IKTPRVDNVVLHRPFYPA--VEGTLCLTGHHLI-LSSRQDNTEELWLLHSNIDAIDKRFV 63
Query: 64 TSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMR 123
SLG + ++CK+FR+ + C + S+ LS +Y F Y P E+
Sbjct: 64 GSLGT-IIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMF--EVI 120
Query: 124 ESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFR 183
E GW P +F W ++ N+ + +C +YPP + VPKS+ + + FR
Sbjct: 121 EDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFR 180
Query: 184 SKERVPVLSYLYKENNAAICRCSQPLSGFY-TRCVDDELLLEAISQTNPGSQFMYVVDTR 242
R PVLSY +K+N I R QPL+G RC +DE L+ A + Y++DTR
Sbjct: 181 HGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRG---YIIDTR 237
Query: 243 PKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLS 302
A RA G G+E E +Y R IE H+++ SL KL+E C +T M +LS
Sbjct: 238 SLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRWLS 297
Query: 303 GLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRT 362
LE+S WL HIK I+ + + E AS+L+H ++G D T QV S+A I+L+P RT
Sbjct: 298 KLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRT 357
Query: 363 FKGLMILIEKEWISMGHKFSQRC---GHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEF 419
+G LIE+EW+ GH F QRC + + K +P+F FLDC+WQ++ QFPC+FEF
Sbjct: 358 IRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEF 417
Query: 420 NENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQ--RKPDFRNPLYKG 477
NENFL+ + +H ++ QFG FLGN + +R L++ +KT S+W ++ Q F NPL++
Sbjct: 418 NENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEA 477
Query: 478 FTMYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKK 537
+ V+ PS P ++ W G++ R+++ + E ++ I + L+ V+ L ++
Sbjct: 478 NNL--VIWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQ 535
Query: 538 L 538
L
Sbjct: 536 L 536
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 294 bits (753), Expect = 2e-79
Identities = 175/486 (36%), Positives = 257/486 (52%), Gaps = 57/486 (11%)
Query: 70 LTLRCKNFRVAHFVLDSDLVCHEVYISLLKLS-QPALPEDLYAFSYNPKSSKEMRESGWK 128
L + CK+ +V + C E L + + +PA PEDL+AF+Y+ E
Sbjct: 87 LHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHT 146
Query: 129 -LIDP--------ISDFGRMGIPNRN-WTITDANRNYEICSTYPPEIVVPKSVTLGTVVG 178
L P ++ RMG +N W ++ N NY++C +YP +++VP +T +
Sbjct: 147 HLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELEN 206
Query: 179 SSKFRSKERVPVLSYLYKENNAAICRCSQP-LSGFYTRCVDDELLLEAISQT---NPGS- 233
+ FRS +R+PV+ Y + N AAI RCSQP +S + R DDE L+ +I++ +PG+
Sbjct: 207 VASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTR 266
Query: 234 -------------------------------------QFMYVVDTRPKLNAMANRAAGKG 256
Q + ++D R A+ANRA G G
Sbjct: 267 ATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGG 326
Query: 257 YENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAI 316
E E+ Y N FMG+ NIH +R+S Q L VC + P S +LS LES+ WL+H+ +
Sbjct: 327 CECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCS-QMPDPSNWLSALESTKWLQHLSVM 385
Query: 317 MDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWIS 376
+ A + + V E VLVHCSDGWDRT Q+ ++A ILLDP+YRT +G +L+E +W+
Sbjct: 386 LKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLD 445
Query: 377 MGHKFSQRCGHLDG--DSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSC 434
GHKF RCGH + D E P+F Q+LD + QL++QFPC FEFNE FL+++ H +SC
Sbjct: 446 FGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSC 505
Query: 435 QFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQ 494
+G FL N +RE +Y++T SVW L +F N LY + VL+P +
Sbjct: 506 LYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDM-VLHPVCHVRALH 564
Query: 495 FWCGMY 500
W +Y
Sbjct: 565 LWTAVY 570
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 282 bits (722), Expect = 7e-76
Identities = 171/492 (34%), Positives = 250/492 (50%), Gaps = 63/492 (12%)
Query: 70 LTLRCKNFRVAHFVLDSDLVCHEVYISLLK-LSQPALPEDLYAFSYNP------KSSKEM 122
L L CK+ +V + C E L + PA EDL++F+Y+ S KE
Sbjct: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
Query: 123 RESGWKLIDPIS-----DFGRMGIPNRN-WTITDANRNYEICSTYPPEIVVPKSVTLGTV 176
+ + ++ + RMG N W I++ N Y++C +YP E++VP +T +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
Query: 177 VGSSKFRSKERVPVLSYLYKENNAAICRCSQP-LSGFYTRCVDDELLLEAISQT------ 229
S FRS +R+P + Y ++ N A I RC QP +S + R DDE L++++++
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
Query: 230 ----------------NPGS-----------------------QFMYVVDTRPKLNAMAN 250
N G Q + ++D R A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
Query: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWL 310
RA G G E + Y N FMG+ NIH +R S Q L +C + P +LS LES+ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385
Query: 311 RHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILI 370
H+ ++ + + + AV ++ VLVHCSDGWDRT Q+ ++A +LLDP+YRT +G +L+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 371 EKEWISMGHKFSQRCGHLDG--DSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIH 428
E EW+ GHKF+ RCGH + D E P+F Q+LDC+ QL QFPC+FEFNE FL+++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 429 DHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPST 488
H +SC FG FL N K+R + E+T SVW L F+N LY VL P
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSS-QSEAVLYPVC 564
Query: 489 VPYNIQFWCGMY 500
N+ W +Y
Sbjct: 565 HVRNLMLWSAVY 576
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 282 bits (722), Expect = 7e-76
Identities = 171/492 (34%), Positives = 250/492 (50%), Gaps = 63/492 (12%)
Query: 70 LTLRCKNFRVAHFVLDSDLVCHEVYISLLK-LSQPALPEDLYAFSYNP------KSSKEM 122
L L CK+ +V + C E L + PA EDL++F+Y+ S KE
Sbjct: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
Query: 123 RESGWKLIDPIS-----DFGRMGIPNRN-WTITDANRNYEICSTYPPEIVVPKSVTLGTV 176
+ + ++ + RMG N W I++ N Y++C +YP E++VP +T +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
Query: 177 VGSSKFRSKERVPVLSYLYKENNAAICRCSQP-LSGFYTRCVDDELLLEAISQT------ 229
S FRS +R+P + Y ++ N A I RC QP +S + R DDE L++++++
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
Query: 230 ----------------NPGS-----------------------QFMYVVDTRPKLNAMAN 250
N G Q + ++D R A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
Query: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWL 310
RA G G E + Y N FMG+ NIH +R S Q L +C + P +LS LES+ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385
Query: 311 RHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILI 370
H+ ++ + + + AV ++ VLVHCSDGWDRT Q+ ++A +LLDP+YRT +G +L+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 371 EKEWISMGHKFSQRCGHLDG--DSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIH 428
E EW+ GHKF+ RCGH + D E P+F Q+LDC+ QL QFPC+FEFNE FL+++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 429 DHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPST 488
H +SC FG FL N K+R + E+T SVW L F+N LY VL P
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSS-QSEAVLYPVC 564
Query: 489 VPYNIQFWCGMY 500
N+ W +Y
Sbjct: 565 HVRNLMLWSAVY 576
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 282 bits (722), Expect = 7e-76
Identities = 171/492 (34%), Positives = 250/492 (50%), Gaps = 63/492 (12%)
Query: 70 LTLRCKNFRVAHFVLDSDLVCHEVYISLLK-LSQPALPEDLYAFSYNP------KSSKEM 122
L L CK+ +V + C E L + PA EDL++F+Y+ S KE
Sbjct: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
Query: 123 RESGWKLIDPIS-----DFGRMGIPNRN-WTITDANRNYEICSTYPPEIVVPKSVTLGTV 176
+ + ++ + RMG N W I++ N Y++C +YP E++VP +T +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
Query: 177 VGSSKFRSKERVPVLSYLYKENNAAICRCSQP-LSGFYTRCVDDELLLEAISQT------ 229
S FRS +R+P + Y ++ N A I RC QP +S + R DDE L++++++
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
Query: 230 ----------------NPGS-----------------------QFMYVVDTRPKLNAMAN 250
N G Q + ++D R A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
Query: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWL 310
RA G G E + Y N FMG+ NIH +R S Q L +C + P +LS LES+ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCT-QMPDPGNWLSALESTKWL 385
Query: 311 RHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILI 370
H+ ++ + + + AV ++ VLVHCSDGWDRT Q+ ++A +LLDP+YRT +G +L+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 371 EKEWISMGHKFSQRCGHLDG--DSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIH 428
E EW+ GHKF+ RCGH + D E P+F Q+LDC+ QL QFPC+FEFNE FL+++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 429 DHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPST 488
H +SC FG FL N K+R + E+T SVW L F+N LY VL P
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSS-QSEAVLYPVC 564
Query: 489 VPYNIQFWCGMY 500
N+ W +Y
Sbjct: 565 HVRNLMLWSAVY 576
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 139 bits (351), Expect = 7e-33
Identities = 87/236 (36%), Positives = 128/236 (54%), Gaps = 20/236 (8%)
Query: 279 MRSSLQKLLEVC----ELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASV 334
+++S +KLL+ C P+ + FL LE S WL I ++ + + + + +SV
Sbjct: 1385 VKASFKKLLKACVPGCPAAEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLD-SGSSV 1443
Query: 335 LVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGH-LDGDSK 393
LV DGWD T QV S+ +L DPFYRT +G +L+EKEW+S GH+FS R H L G S
Sbjct: 1444 LVGLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSS 1503
Query: 394 EVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDREDL-RV 452
+P+F QFLDC+ Q+ QFP FEF++ +L + H S +F FL + +R +L +
Sbjct: 1504 GFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELGLL 1563
Query: 453 YEK---------THSVWPF---LVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQFW 496
YE+ SVW + L +R P F N +Y VL P + N++ W
Sbjct: 1564 YEEKGERRGQVPCRSVWEYVDRLSKRTPVFHNYMYAPEDA-EVLRPYSNVSNLKVW 1618
Score = 35.4 bits (80), Expect = 0.18
Identities = 18/57 (31%), Positives = 30/57 (52%)
Query: 148 ITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICR 204
I+ NR Y IC +YP ++VP+SV + S+ + R PV+ + + A + R
Sbjct: 1152 ISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLR 1208
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 138 bits (348), Expect = 2e-32
Identities = 120/457 (26%), Positives = 196/457 (42%), Gaps = 80/457 (17%)
Query: 70 LTLRCKNFRVAHFVLDSD--LVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMRE--- 124
L + CK+FR+ F D +V +++ SQP + L+AF Y K
Sbjct: 134 LIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKIN 193
Query: 125 --------------------SGWK--LIDPISDFGR--MGIPNRNWTITDANRNYEICST 160
S K L + SD+ R W + N Y I +
Sbjct: 194 GIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWRVCSINEGYMISTC 253
Query: 161 YPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDE 220
P IVVP S+ + S R+P+ + + N +A+ R + R + D+
Sbjct: 254 LPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSH-SNGSALVRMALIKDVLQQRKI-DQ 311
Query: 221 LLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMR 280
+ AI++++P +Y D L NI ++
Sbjct: 312 RICNAITKSHPQRSDVYKSDLDKTL----------------------------PNIQEVQ 343
Query: 281 SSLQKLLEVC--ELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHC 338
++ KL ++C E T ++LS LE++ WL +++A + + ++ + SV++
Sbjct: 344 AAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQE 403
Query: 339 SDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPI 398
+G D + V S+ ++LDP++RT G LI+KEW+ G++F RC HL KE SP+
Sbjct: 404 EEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE-SPL 462
Query: 399 FTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDR----------E 448
F FLD WQL+EQ+P AFEF+E +L ++D FG FL N R +
Sbjct: 463 FLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISK 522
Query: 449 DLRVYE----KTHSVW----PFLVQRKPDFRNPLYKG 477
++++ + K SVW F + + F NP Y G
Sbjct: 523 NIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIG 559
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 129 bits (323), Expect = 1e-29
Identities = 74/187 (39%), Positives = 106/187 (56%), Gaps = 5/187 (2%)
Query: 265 NIRFRFMGIENIHVMRSSLQKLLEVCELKT-PTMSE--FLSGLESSGWLRHIKAIMDAGI 321
N F + I +++S +KL+ C T PT SE FL L S W + IM +
Sbjct: 1335 NCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAV 1394
Query: 322 FITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKF 381
+++ ++ +SVLV +GWD TAQV S+ +L DPFYRT +G +L+EKEW+S GHKF
Sbjct: 1395 VVSEVLE-NGSSVLVCLEEGWDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKF 1453
Query: 382 SQRCG-HLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFL 440
SQR L+ +P+F QFLDC+ Q+ Q+P FEFN +L + H S +F FL
Sbjct: 1454 SQRSSLTLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFL 1513
Query: 441 GNCQKDR 447
+ +R
Sbjct: 1514 LDSDYER 1520
Score = 33.9 bits (76), Expect = 0.53
Identities = 16/57 (28%), Positives = 31/57 (54%)
Query: 148 ITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICR 204
IT +NR Y +C +YP +VVP++V ++ ++ R+PV+ + + + R
Sbjct: 1140 ITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLR 1196
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 122 bits (307), Expect = 9e-28
Identities = 113/430 (26%), Positives = 183/430 (42%), Gaps = 51/430 (11%)
Query: 70 LTLRCKNFRVAHFVL--DSDLVCHEVYISLLKLSQ-PALPEDLYAFSYNPKSSKEM---R 123
L + CK+ RV F L + + ++ +Q P L + L+ FSY +
Sbjct: 139 LIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDP 198
Query: 124 ESGWKLIDPISDFG---RMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSS 180
++ + D + D+ N + N Y++C P VVP + V
Sbjct: 199 KNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENV---Q 255
Query: 181 KFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVD 240
+F+ +P+ + +A + + P D+ +L+ G +Y
Sbjct: 256 RFQG-HGIPIWCWSCHNGSALLKMSALPKE-------QDDGILQIQKSFLDG---IYKTI 304
Query: 241 TRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKT--PTMS 298
RP + + ED +N F+ ++ I S ++L + T
Sbjct: 305 HRPPYEIV---------KTEDLSSN----FLSLQEIQTAYSKFKQLFLIDNSTEFWDTDI 351
Query: 299 EFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDP 358
++ S LESS WL I+ + I IT+ ++ + +VL+ + D + S+ +++DP
Sbjct: 352 KWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDP 411
Query: 359 FYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFE 418
RT G LI+KEW+ GH F RC HL + KE P+F FLDC+WQL+ Q P AFE
Sbjct: 412 HCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFE 471
Query: 419 FNENFLLEIHDHVFSCQFGNFLGNC--QKDREDLRVYEKTHS-------VWPFLVQRKPD 469
F E +L + D ++ F F N QKD R + T S VW + VQ +P
Sbjct: 472 FTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPK 531
Query: 470 ----FRNPLY 475
+NPLY
Sbjct: 532 AQTLLKNPLY 541
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 108 bits (269), Expect = 2e-23
Identities = 81/305 (26%), Positives = 137/305 (44%), Gaps = 35/305 (11%)
Query: 144 RNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAIC 203
R W ++ N +++ ++ P VP + V + + R P LS+ + + +
Sbjct: 212 RGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLL 270
Query: 204 RCSQPLSGFYTRCVDDELLLEAIS-QTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDN 262
RC GFYT ++ + A+ G + +VDT +L ++A +
Sbjct: 271 RCG----GFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLA----------DVQ 316
Query: 263 YANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIF 322
A++R R + + + V ++LS LE + WL +++A +
Sbjct: 317 LAHLRLRALCLPDSSVAED-----------------KWLSALEGTRWLDYVRACLRKASD 359
Query: 323 ITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFS 382
I+ V SV++ D + S+ +L P RT G L+++EW++ GH F
Sbjct: 360 ISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFL 419
Query: 383 QRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGN 442
R G + E +P+F FLDC+WQL++QFP FEF+E FLL +HD V FL N
Sbjct: 420 TRLGGTG--ASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRN 477
Query: 443 CQKDR 447
+R
Sbjct: 478 TPWER 482
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 108 bits (269), Expect = 2e-23
Identities = 81/305 (26%), Positives = 137/305 (44%), Gaps = 35/305 (11%)
Query: 144 RNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAIC 203
R W ++ N +++ ++ P VP + V + + R P LS+ + + +
Sbjct: 140 RGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLL 198
Query: 204 RCSQPLSGFYTRCVDDELLLEAIS-QTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDN 262
RC GFYT ++ + A+ G + +VDT +L ++A +
Sbjct: 199 RCG----GFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLA----------DVQ 244
Query: 263 YANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIF 322
A++R R + + + V ++LS LE + WL +++A +
Sbjct: 245 LAHLRLRALCLPDSSVAED-----------------KWLSALEGTRWLDYVRACLRKASD 287
Query: 323 ITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFS 382
I+ V SV++ D + S+ +L P RT G L+++EW++ GH F
Sbjct: 288 ISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFL 347
Query: 383 QRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGN 442
R G + E +P+F FLDC+WQL++QFP FEF+E FLL +HD V FL N
Sbjct: 348 TRLGGTG--ASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRN 405
Query: 443 CQKDR 447
+R
Sbjct: 406 TPWER 410
>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
sapiens]
Length = 1691
Score = 39.3 bits (90), Expect = 0.013
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Query: 554 LGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCC 613
L I+ G P P GFMGI G L L + ++ G+ + +G+
Sbjct: 1006 LPGIIKGVSGKP--GPPGFMGIRG-LPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGAS 1062
Query: 614 EIVG----SLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGN 669
+ G + + + ISG G G SG T G ++G G G+SG+
Sbjct: 1063 GLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGD 1122
Query: 670 LGISEARGFSGDMGILGDTGISKAS 694
+G+ A GF G G+ G+ G+ +S
Sbjct: 1123 VGLPGAPGFPGVAGMRGEPGLPGSS 1147
Score = 33.5 bits (75), Expect = 0.69
Identities = 33/129 (25%), Positives = 50/129 (38%), Gaps = 10/129 (7%)
Query: 563 GSP-LTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRA 621
GSP L G G+ GD +E G + ++G D G +
Sbjct: 1054 GSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD---------GLIGN 1104
Query: 622 INISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGD 681
I G+ G +G+SGD+ A GF G+ G + ++G G +G + G G
Sbjct: 1105 IGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGP 1164
Query: 682 MGILGDTGI 690
G G G+
Sbjct: 1165 KGFPGFPGL 1173
Score = 33.1 bits (74), Expect = 0.90
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 622 INISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGD 681
+ +SGDVG+ A G G G + G+ G+ A G G+ G+ +GF G
Sbjct: 1117 VGVSGDVGLPGAPGFPG------VAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGF 1170
Query: 682 MGILGDTGI 690
G+ G G+
Sbjct: 1171 PGLHGLNGL 1179
Score = 31.2 bits (69), Expect = 3.4
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 624 ISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGI--SEARGFSGD 681
+ GD G+ GI+G A GF +G G + G G LG + GF G+
Sbjct: 170 MKGDPGLPGLDGITGPQ---GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGE 226
Query: 682 MGILGDTGI 690
G+ GD G+
Sbjct: 227 KGVKGDVGL 235
>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
sapiens]
Length = 1690
Score = 39.3 bits (90), Expect = 0.013
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Query: 554 LGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCC 613
L I+ G P P GFMGI G L L + ++ G+ + +G+
Sbjct: 1005 LPGIIKGVSGKP--GPPGFMGIRG-LPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGAS 1061
Query: 614 EIVG----SLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGN 669
+ G + + + ISG G G SG T G ++G G G+SG+
Sbjct: 1062 GLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGD 1121
Query: 670 LGISEARGFSGDMGILGDTGISKAS 694
+G+ A GF G G+ G+ G+ +S
Sbjct: 1122 VGLPGAPGFPGVAGMRGEPGLPGSS 1146
Score = 33.5 bits (75), Expect = 0.69
Identities = 33/129 (25%), Positives = 50/129 (38%), Gaps = 10/129 (7%)
Query: 563 GSP-LTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRA 621
GSP L G G+ GD +E G + ++G D G +
Sbjct: 1053 GSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD---------GLIGN 1103
Query: 622 INISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGD 681
I G+ G +G+SGD+ A GF G+ G + ++G G +G + G G
Sbjct: 1104 IGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGP 1163
Query: 682 MGILGDTGI 690
G G G+
Sbjct: 1164 KGFPGFPGL 1172
Score = 33.1 bits (74), Expect = 0.90
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 622 INISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGD 681
+ +SGDVG+ A G G G + G+ G+ A G G+ G+ +GF G
Sbjct: 1116 VGVSGDVGLPGAPGFPG------VAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGF 1169
Query: 682 MGILGDTGI 690
G+ G G+
Sbjct: 1170 PGLHGLNGL 1178
Score = 31.2 bits (69), Expect = 3.4
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 624 ISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGI--SEARGFSGD 681
+ GD G+ GI+G A GF +G G + G G LG + GF G+
Sbjct: 169 MKGDPGLPGLDGITGPQ---GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGE 225
Query: 682 MGILGDTGI 690
G+ GD G+
Sbjct: 226 KGVKGDVGL 234
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 35.8 bits (81), Expect = 0.14
Identities = 34/127 (26%), Positives = 47/127 (37%), Gaps = 12/127 (9%)
Query: 571 GFMGINGDLNTLMENGTLSREG--------GLRAQMDQVKSQGADLHHNCCEIVGSLRAI 622
G G++G+ GTL EG G + + SQG ++G+ +
Sbjct: 1561 GLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGST 1620
Query: 623 NISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDM 682
G +G G+ GD+ TG G G G G G+ RGF GD
Sbjct: 1621 GRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGI----PGYGQMGRKGVKGPRGFPGDA 1676
Query: 683 GILGDTG 689
G GD G
Sbjct: 1677 GQKGDIG 1683
Score = 31.6 bits (70), Expect = 2.6
Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 14/121 (11%)
Query: 571 GFMGINGDLNTLMENGTLSREG--GLRAQMDQVKSQGADLHHNCCEIVGSLRAINISGDV 628
G G G + G+ REG GLR + + G G+L A + G
Sbjct: 1537 GRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGP---------TGTLGAEGLQGPQ 1587
Query: 629 GISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDT 688
G G G+ + G G+ GA +TG G LG G GD+G +G T
Sbjct: 1588 GSQGNPGRKGEKGSQGQKGPQGSPGLMGAKG---STGRPGLLGKKGEPGLPGDLGPVGQT 1644
Query: 689 G 689
G
Sbjct: 1645 G 1645
>gi|44889483 cerebellar degeneration-related protein 1, 34kDa [Homo
sapiens]
Length = 262
Score = 35.0 bits (79), Expect = 0.24
Identities = 23/65 (35%), Positives = 29/65 (44%)
Query: 619 LRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGF 678
L AI++ D E M D+ GFS G G S +SG LG+ RGF
Sbjct: 112 LEAIDLREDKDFLEDMDSLEDLEAIGRCGFSGRHGFFGRRRFSGRPKLSGRLGLLGRRGF 171
Query: 679 SGDMG 683
SG +G
Sbjct: 172 SGRLG 176
Score = 30.4 bits (67), Expect = 5.9
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 627 DVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILG 686
D+ + E M + D+ E T F +DL AMD+ E ++ E D+ +L
Sbjct: 42 DINLMEDMALLEDVDLLEDTDFLEDLDFSEAMDLREDKDFLEDMDSLEDMALLEDVDLLE 101
Query: 687 DT 688
DT
Sbjct: 102 DT 103
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 34.3 bits (77), Expect = 0.41
Identities = 34/137 (24%), Positives = 52/137 (37%), Gaps = 10/137 (7%)
Query: 560 QHLGSPLTNP-----LGFMGINGDLNTLMENGTLSREG--GLRAQMDQVKSQGADLHHNC 612
Q L P+ +P G++G+ G +G G G R +M G
Sbjct: 741 QGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGP 800
Query: 613 CEIVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGI 672
+ G+ + + G G+ G+ GD+ G+ G+ G M G+ G+ G
Sbjct: 801 PGLDGNPGELGLPGPPGVP---GLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGE 857
Query: 673 SEARGFSGDMGILGDTG 689
G SGD G GD G
Sbjct: 858 QGVPGVSGDPGFQGDKG 874
Score = 32.3 bits (72), Expect = 1.5
Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 10/126 (7%)
Query: 566 LTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRAINIS 625
L P G +G G +G R+G Q Q QG D G ++
Sbjct: 1425 LPGPRGVVGRQGLEGIAGPDGLPGRDG----QAGQQGEQGDDGDPGPMGPAGKRGNPGVA 1480
Query: 626 GDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGIL 685
G G G G+ +G LG G TG+ GN G ++G GD G +
Sbjct: 1481 GLPGAQGPPGFKGE------SGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEM 1534
Query: 686 GDTGIS 691
G G++
Sbjct: 1535 GFPGMA 1540
Score = 32.0 bits (71), Expect = 2.0
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 18/87 (20%)
Query: 615 IVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISE 674
++GS+ + GD G G+SGD GF D G G A G G LG
Sbjct: 842 LMGSVGEPGLKGDKGEQGVPGVSGD------PGFQGDKGSQGLPGFPGARGKPGPLGKVG 895
Query: 675 ARG------------FSGDMGILGDTG 689
+G F GD+G GD G
Sbjct: 896 DKGSIGFPGPPGPEGFPGDIGPPGDNG 922
Score = 31.6 bits (70), Expect = 2.6
Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 7/125 (5%)
Query: 569 PLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRAINISGDV 628
P G MG G + E G L E G++ + + + G ++G + GD
Sbjct: 1142 PPGEMGPKGPPGAVGEPG-LPGEAGMKGDLGPLGTPGEQ------GLIGQRGEPGLEGDS 1194
Query: 629 GISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDT 688
G G+ GD G + G G M G G G+ G SG G G T
Sbjct: 1195 GPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRT 1254
Query: 689 GISKA 693
G A
Sbjct: 1255 GAKGA 1259
>gi|4506537 receptor-interacting serine-threonine kinase 2 [Homo
sapiens]
Length = 540
Score = 33.9 bits (76), Expect = 0.53
Identities = 39/164 (23%), Positives = 71/164 (43%), Gaps = 43/164 (26%)
Query: 444 QKDREDLR--VYEKTHSVWPFLVQRKP--DFRNPLYKGFTMYG----VLNPSTVPYNIQF 495
QK R ++ +Y W L +++P D NPL +++ V+N ++PY+I
Sbjct: 202 QKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPH 261
Query: 496 WCGMYNRFDKG-----------------LQP------KQSMLESLLEIKKQRAM-LETDV 531
M + + G L+P + + LE+++++KK + + + +
Sbjct: 262 RARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQSVSSAI 321
Query: 532 HELEKK-------LKVRDEPPEEICTCSQLGNILSQHLGSPLTN 568
H +KK + V P EE C SQ L ++ GSP T+
Sbjct: 322 HLCDKKKMELSLNIPVNHGPQEESCGSSQ----LHENSGSPETS 361
>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
Length = 689
Score = 33.9 bits (76), Expect = 0.53
Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 2/121 (1%)
Query: 571 GFMGINGDLNTLMENGTLSREG--GLRAQMDQVKSQGADLHHNCCEIVGSLRAINISGDV 628
G G GD+ E G G G+R +G H +VG++ A G+
Sbjct: 208 GKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEE 267
Query: 629 GISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDT 688
G G +G+ + G GI G + GI+G G G G G G
Sbjct: 268 GPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQP 327
Query: 689 G 689
G
Sbjct: 328 G 328
>gi|122937273 hypothetical protein LOC131149 [Homo sapiens]
Length = 477
Score = 33.9 bits (76), Expect = 0.53
Identities = 19/61 (31%), Positives = 24/61 (39%)
Query: 629 GISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDT 688
G+ G GD C G D G G+ + G G G +G GD G GD+
Sbjct: 188 GVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDS 247
Query: 689 G 689
G
Sbjct: 248 G 248
Score = 32.3 bits (72), Expect = 1.5
Identities = 30/119 (25%), Positives = 42/119 (35%), Gaps = 7/119 (5%)
Query: 571 GFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRAINISGDVGI 630
G G G+ + G + GG++ Q K D NC + G G G+
Sbjct: 167 GKPGAQGEPGPKGDKGNIGL-GGVKGQ----KGSKGDTCGNCTK--GEKGDQGAMGSPGL 219
Query: 631 SEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDTG 689
G G+ G D G CG G G G+ +G GD G+ G +G
Sbjct: 220 HGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSG 278
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 33.1 bits (74), Expect = 0.90
Identities = 18/43 (41%), Positives = 20/43 (46%)
Query: 647 GFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDTG 689
G+ G+ GA I G G G GF GDMGI GD G
Sbjct: 787 GYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRG 829
>gi|194097442 protein tyrosine phosphatase, receptor type, N
polypeptide 2 isoform 3 precursor [Homo sapiens]
Length = 986
Score = 33.1 bits (74), Expect = 0.90
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 9/82 (10%)
Query: 278 VMRSSLQKLLEVCELKTPTMSEFLS----GLESSGWLRHIKAIMDAGIFITKAVKVEKAS 333
++RS K L+ E +T T FLS G+ SS ++++D + K +
Sbjct: 857 LVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSS-----RSLLDFRRKVNKCYRGRSCP 911
Query: 334 VLVHCSDGWDRTAQVCSVASIL 355
++VHCSDG R+ + +L
Sbjct: 912 IIVHCSDGAGRSGTYVLIDMVL 933
>gi|194097440 protein tyrosine phosphatase, receptor type, N
polypeptide 2 isoform 1 precursor [Homo sapiens]
Length = 1015
Score = 33.1 bits (74), Expect = 0.90
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 9/82 (10%)
Query: 278 VMRSSLQKLLEVCELKTPTMSEFLS----GLESSGWLRHIKAIMDAGIFITKAVKVEKAS 333
++RS K L+ E +T T FLS G+ SS ++++D + K +
Sbjct: 886 LVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSS-----RSLLDFRRKVNKCYRGRSCP 940
Query: 334 VLVHCSDGWDRTAQVCSVASIL 355
++VHCSDG R+ + +L
Sbjct: 941 IIVHCSDGAGRSGTYVLIDMVL 962
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,905,583
Number of Sequences: 37866
Number of extensions: 1207711
Number of successful extensions: 3688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3216
Number of HSP's gapped (non-prelim): 416
length of query: 704
length of database: 18,247,518
effective HSP length: 109
effective length of query: 595
effective length of database: 14,120,124
effective search space: 8401473780
effective search space used: 8401473780
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.