Guide to the Human Genome
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Name: RIPK2 Sequence: fasta or formatted (540aa) NCBI GI: 4506537
Description:

receptor-interacting serine-threonine kinase 2

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
Additional Serine / Threonine Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4         29           2
 C cysteine            1.9         10           1
 D aspartate           4.6         25           1
 E glutamate           7.0         38           2
 F phenylalanine       2.4         13           1
 G glycine             4.1         22           2
 H histidine           4.1         22           2
 I isoleucine          6.9         37           2
 K lysine              5.7         31           3
 L leucine            11.1         60           2
 M methionine          2.6         14           2
 N asparagine          4.4         24           1
 P proline             6.5         35           2
 Q glutamine           5.0         27           2
 R arginine            5.2         28           1
 S serine             10.0         54           2
 T threonine           4.4         24           2
 V valine              4.6         25           2
 W tryptophan          1.3          7           1
 Y tyrosine            2.8         15           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   receptor-interacting serine-threonine kinase 2 
RIPK4                 0.164   ankyrin repeat domain 3 
ANKK1                 0.154   ankyrin repeat and kinase domain containing 1 
RIPK3                 0.112   receptor-interacting serine-threonine kinase 3 [Homo...
RIPK1                 0.100   receptor (TNFRSF)-interacting serine-threonine kinas...
TNNI3K                0.094   TNNI3 interacting kinase isoform b 
TNNI3K                0.094   TNNI3 interacting kinase isoform a 
MAP3K7                0.077   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.077   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.077   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.077   mitogen-activated protein kinase kinase kinase 7 isof...
BRAF                  0.073   B-Raf 
NPR2                  0.070   natriuretic peptide receptor B precursor 
ZAK                   0.070   MLK-related kinase isoform 2 
MAP3K13               0.070   mitogen-activated protein kinase kinase kinase 13 [Ho...
IRAK1                 0.069   interleukin-1 receptor-associated kinase 1 isoform 3...
IRAK1                 0.069   interleukin-1 receptor-associated kinase 1 isoform 2...
IRAK1                 0.069   interleukin-1 receptor-associated kinase 1 isoform 1...
MAP3K12               0.068   mitogen-activated protein kinase kinase kinase 12 [H...
TEC                   0.068   tec protein tyrosine kinase 
ZAP70                 0.068   zeta-chain associated protein kinase 70kDa isoform 2...
ZAP70                 0.068   zeta-chain associated protein kinase 70kDa isoform 1...
MAP3K9                0.067   mitogen-activated protein kinase kinase kinase 9 [Ho...
TXK                   0.067   TXK tyrosine kinase 
MAP3K10               0.067   mitogen-activated protein kinase kinase kinase 10 [H...
ZAK                   0.066   MLK-related kinase isoform 1 
KIAA1804              0.062   mixed lineage kinase 4 
ARAF                  0.061   v-raf murine sarcoma 3611 viral oncogene homolog [Hom...
IRAK4                 0.061   interleukin-1 receptor-associated kinase 4 isoform ...
IRAK4                 0.061   interleukin-1 receptor-associated kinase 4 isoform ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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