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Search of human proteins with 21361598
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
(540 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 1078 0.0
gi|52630447 palmitoylated membrane protein 2 [Homo sapiens] 779 0.0
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 415 e-116
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 406 e-113
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 397 e-110
gi|4505237 palmitoylated membrane protein 1 [Homo sapiens] 357 2e-98
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 348 9e-96
gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] 343 3e-94
gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] 304 2e-82
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 171 2e-42
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 167 2e-41
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 167 2e-41
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 164 1e-40
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 158 1e-38
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 158 1e-38
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 158 1e-38
gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens] 154 3e-37
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 152 6e-37
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 152 7e-37
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 152 7e-37
gi|226874833 guanylate kinase 1 isoform b [Homo sapiens] 107 2e-23
gi|226874831 guanylate kinase 1 isoform a [Homo sapiens] 107 2e-23
gi|4504221 guanylate kinase 1 isoform b [Homo sapiens] 107 2e-23
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 61 2e-09
gi|10092691 tight junction protein 3 [Homo sapiens] 55 2e-07
gi|42518065 tight junction protein 2 (zona occludens 2) isoform ... 50 5e-06
gi|42518070 tight junction protein 2 (zona occludens 2) isoform ... 50 5e-06
gi|95089461 discs large homolog 5 [Homo sapiens] 50 7e-06
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 50 7e-06
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 49 9e-06
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 1078 bits (2787), Expect = 0.0
Identities = 540/540 (100%), Positives = 540/540 (100%)
Query: 1 MQQVLENLTELPSSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEAVSDNNLELV 60
MQQVLENLTELPSSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEAVSDNNLELV
Sbjct: 1 MQQVLENLTELPSSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEAVSDNNLELV 60
Query: 61 NEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNNSSINN 120
NEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNNSSINN
Sbjct: 61 NEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNNSSINN 120
Query: 121 QLLPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNG 180
QLLPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNG
Sbjct: 121 QLLPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNG 180
Query: 181 HEVGNNPKELQELLKNISGSVTLKILPSYRDTITPQQVFVKCHFDYNPYNDNLIPCKEAG 240
HEVGNNPKELQELLKNISGSVTLKILPSYRDTITPQQVFVKCHFDYNPYNDNLIPCKEAG
Sbjct: 181 HEVGNNPKELQELLKNISGSVTLKILPSYRDTITPQQVFVKCHFDYNPYNDNLIPCKEAG 240
Query: 241 LKFSKGEILQIVNREDPNWWQASHVKEGGSAGLIPSQFLEEKRKAFVRRDWDNSGPFCGT 300
LKFSKGEILQIVNREDPNWWQASHVKEGGSAGLIPSQFLEEKRKAFVRRDWDNSGPFCGT
Sbjct: 241 LKFSKGEILQIVNREDPNWWQASHVKEGGSAGLIPSQFLEEKRKAFVRRDWDNSGPFCGT 300
Query: 301 ISSKKKKKMMYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIV 360
ISSKKKKKMMYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIV
Sbjct: 301 ISSKKKKKMMYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIV 360
Query: 361 LNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKID 420
LNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKID
Sbjct: 361 LNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKID 420
Query: 421 SILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKL 480
SILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKL
Sbjct: 421 SILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKL 480
Query: 481 LTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWVY 540
LTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWVY
Sbjct: 481 LTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWVY 540
>gi|52630447 palmitoylated membrane protein 2 [Homo sapiens]
Length = 552
Score = 779 bits (2011), Expect = 0.0
Identities = 377/543 (69%), Positives = 464/543 (85%), Gaps = 5/543 (0%)
Query: 1 MQQVLENLTELPSSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEAVSDNNLELV 60
MQQVL+NL LPS+TGA E+DLIFL+GIME+PIV+SLAKAHERLE++KLEAV DNNLELV
Sbjct: 12 MQQVLDNLGSLPSATGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEAVRDNNLELV 71
Query: 61 NEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNNSSINN 120
EIL D+ + AEL IL+EPHFQSLLE HD VASK Y++PP SP ++ + +N
Sbjct: 72 QEILRDLAHVAEQSSTAAELAHILQEPHFQSLLETHDSVASKTYETPPPSPGLD-PTFSN 130
Query: 121 QLLPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNG 180
Q +P DA+R++GI K AGE LGVTFRVE +LVIARILHGGM+ +QGLLHVGDIIKEVNG
Sbjct: 131 QPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNG 190
Query: 181 HEVGNNPKELQELLKNISGSVTLKILPSYRDTITPQQVFVKCHFDYNPYNDNLIPCKEAG 240
VG++P+ LQELL+N SGSV LKILPSY++ P+QVFVKCHFDY+P D+LIPCKEAG
Sbjct: 191 QPVGSDPRALQELLRNASGSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAG 250
Query: 241 LKFSKGEILQIVNREDPNWWQASHVKEGGSAGLIPSQFLEEKRKAFVRRDWD---NSGPF 297
L+F+ G++LQIVN++D NWWQA HV EGGSAGLIPSQ LEEKRKAFV+RD + NSG
Sbjct: 251 LRFNAGDLLQIVNQDDANWWQACHV-EGGSAGLIPSQLLEEKRKAFVKRDLELTPNSGTL 309
Query: 298 CGTISSKKKKKMMYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNR 357
CG++S KKKK+MMYLTT+NAEFDRHE+ IYEEVA+MPPF+RKTLVLIGAQGVGRRSLKN+
Sbjct: 310 CGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNK 369
Query: 358 FIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGT 417
I+ +P R+GTTVP+TSR+P++ E++GQ Y FVSR EMEAD++AG+YLEHGEYEGNLYGT
Sbjct: 370 LIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGT 429
Query: 418 KIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGIT 477
+IDSI VV G+ C+LDVNPQA+KVLRT+EF+PYVVFI AP+ ETLRAM++A +++GI+
Sbjct: 430 RIDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGIS 489
Query: 478 TKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPIS 537
TK LT++DL++TV+ES+RIQR Y HYFDL ++N NL++ F +LQTA+EKLR EPQWVP+S
Sbjct: 490 TKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPVS 549
Query: 538 WVY 540
WVY
Sbjct: 550 WVY 552
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 415 bits (1067), Expect = e-116
Identities = 233/573 (40%), Positives = 343/573 (59%), Gaps = 49/573 (8%)
Query: 1 MQQVLENLTELPSSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEAVSD---NNL 57
+ QVL++L E+ + T E DL FL + ++ + +L ++++ + + + +
Sbjct: 341 VSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAV 400
Query: 58 ELVNEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDS-------PPSS 110
+ E+LE+I+ + + EL IL +PHF +LL+ HD+VA + Y PP+S
Sbjct: 401 QRAKEVLEEIS-CYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTS 459
Query: 111 PEMNNSSINN-----QLLPVDAIRILGIHKRAGEPLGVTFRV-ENNDLVIARILHGGMID 164
P +N S + + V +R++ K EP+G+T ++ E N ++ARI+HGGMI
Sbjct: 460 PYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIH 519
Query: 165 RQGLLHVGDIIKEVNGHEVGNNPKE-LQELLKNISGSVTLKILPSYR----------DTI 213
RQG LHVGD I+E+NG V N E LQ++L+ + GS+T KI+PSYR T
Sbjct: 520 RQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTT 579
Query: 214 TPQ--QVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQAS-HVKEGGS 270
P+ Q++V+ F+Y+P D+LIPCKEAG++F G+I+QI++++D NWWQ + G+
Sbjct: 580 QPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGT 639
Query: 271 AGLIPSQFLEEKRKAFV--RRDWDNSGPFCGTISSKKKK-KMMYLTTRNAEFDRHEIQIY 327
AGLIPS L+E R A + + C KKK+ K YL NA FD+ ++ Y
Sbjct: 640 AGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTY 699
Query: 328 EEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAY 387
EEV K+P F+RKTLVL+GA GVGRR +KN I +P RF +P T+R P++DE++G+ Y
Sbjct: 700 EEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNY 759
Query: 388 KFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTS 447
FVS +M DI +YLE+G +E +YGTK+++I ++ + G ILDV PQALKVLRT+
Sbjct: 760 YFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTA 819
Query: 448 EFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLI 507
EF P+VVFIAAP IT L D L++ ES +QR Y HYFDL
Sbjct: 820 EFAPFVVFIAAPT---------------ITPGLNEDESLQRLQKESDILQRTYAHYFDLT 864
Query: 508 IINDNLDKAFEKLQTAIEKLRMEPQWVPISWVY 540
IIN+ +D+ L+ A+E + PQWVP+SWVY
Sbjct: 865 IINNEIDETIRHLEEAVELVCTAPQWVPVSWVY 897
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 406 bits (1043), Expect = e-113
Identities = 231/573 (40%), Positives = 340/573 (59%), Gaps = 54/573 (9%)
Query: 1 MQQVLENLTELPSSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEAVSD---NNL 57
+ QVL++L E+ + T E DL FL + ++ + +L ++++ + + + +
Sbjct: 347 VSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAV 406
Query: 58 ELVNEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDS-------PPSS 110
+ E+LE+I+ + + EL IL +PHF +LL+ HD+VA + Y PP+S
Sbjct: 407 QRAKEVLEEIS-CYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTS 465
Query: 111 PEMNNSSINN-----QLLPVDAIRILGIHKRAGEPLGVTFRV-ENNDLVIARILHGGMID 164
P +N S + + V +R++ K EP+G+T ++ E N ++ARI+HGGMI
Sbjct: 466 PYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIH 525
Query: 165 RQGLLHVGDIIKEVNGHEVGNNPKE-LQELLKNISGSVTLKILPSYR----------DTI 213
RQG LHVGD I+E+NG V N E LQ++L+ + GS+T KI+PSYR T
Sbjct: 526 RQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTT 585
Query: 214 TPQ--QVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQAS-HVKEGGS 270
P+ Q++V+ F+Y+P D+LIPCKEAG++F G+I+QI++++D NWWQ + G+
Sbjct: 586 QPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGT 645
Query: 271 AGLIPSQFLEEKRKAFV--RRDWDNSGPFCGTISSKKKK-KMMYLTTRNAEFDRHEIQIY 327
AGLIPS L+E R A + + C KKK+ K YL NA+ + Y
Sbjct: 646 AGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAD-----LVTY 700
Query: 328 EEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAY 387
EEV K+P F+RKTLVL+GA GVGRR +KN I +P RF +P T+R P++DE++G+ Y
Sbjct: 701 EEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNY 760
Query: 388 KFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTS 447
FVS +M DI +YLE+G +E +YGTK+++I ++ + G ILDV PQALKVLRT+
Sbjct: 761 YFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTA 820
Query: 448 EFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLI 507
EF P+VVFIAAP IT L D L++ ES +QR Y HYFDL
Sbjct: 821 EFAPFVVFIAAPT---------------ITPGLNEDESLQRLQKESDILQRTYAHYFDLT 865
Query: 508 IINDNLDKAFEKLQTAIEKLRMEPQWVPISWVY 540
IIN+ +D+ L+ A+E + PQWVP+SWVY
Sbjct: 866 IINNEIDETIRHLEEAVELVCTAPQWVPVSWVY 898
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 397 bits (1020), Expect = e-110
Identities = 231/596 (38%), Positives = 340/596 (57%), Gaps = 77/596 (12%)
Query: 1 MQQVLENLTELPSSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEAVSD---NNL 57
+ QVL++L E+ + T E DL FL + ++ + +L ++++ + + + +
Sbjct: 347 VSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAV 406
Query: 58 ELVNEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDS-------PPSS 110
+ E+LE+I+ + + EL IL +PHF +LL+ HD+VA + Y PP+S
Sbjct: 407 QRAKEVLEEIS-CYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTS 465
Query: 111 PEMNNSSINN-----QLLPVDAIRILGIHKRAGEPLGVTFRV-ENNDLVIARILHGGMID 164
P +N S + + V +R++ K EP+G+T ++ E N ++ARI+HGGMI
Sbjct: 466 PYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIH 525
Query: 165 RQGLLHVGDIIKEVNGHEVGNNPKE-LQELLKNISGSVTLKILPSYR------------- 210
RQG LHVGD I+E+NG V N E LQ++L+ + GS+T KI+PSYR
Sbjct: 526 RQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPST 585
Query: 211 --------------------DTITPQ--QVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEI 248
T P+ Q++V+ F+Y+P D+LIPCKEAG++F G+I
Sbjct: 586 SRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDI 645
Query: 249 LQIVNREDPNWWQAS-HVKEGGSAGLIPSQFLEEKRKAFV--RRDWDNSGPFCGTISSKK 305
+QI++++D NWWQ + G+AGLIPS L+E R A + + C KK
Sbjct: 646 IQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKK 705
Query: 306 KK-KMMYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPT 364
K+ K YL NA+ + YEEV K+P F+RKTLVL+GA GVGRR +KN I +P
Sbjct: 706 KQYKDKYLAKHNAD-----LVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPD 760
Query: 365 RFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILE 424
RF +P T+R P++DE++G+ Y FVS +M DI +YLE+G +E +YGTK+++I +
Sbjct: 761 RFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRK 820
Query: 425 VVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDS 484
+ + G ILDV PQALKVLRT+EF P+VVFIAAP IT L D
Sbjct: 821 IHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPT---------------ITPGLNEDE 865
Query: 485 DLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWVY 540
L++ ES +QR Y HYFDL IIN+ +D+ L+ A+E + PQWVP+SWVY
Sbjct: 866 SLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY 921
>gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]
Length = 466
Score = 357 bits (916), Expect = 2e-98
Identities = 183/421 (43%), Positives = 266/421 (63%), Gaps = 25/421 (5%)
Query: 125 VDAIRILGIHKRAGEPLGVTFRV-ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV 183
V +R++ K EP+G+T ++ E +ARILHGGMI RQG LHVGD I E+NG V
Sbjct: 66 VRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNV 125
Query: 184 GNNP-KELQELLKNISGSVTLKILPSYRDTITPQQVFVKCHFDYNPYNDNLIPCKEAGLK 242
N+ +LQ+ +K G ++LK++P+ + + Q+F++ FDY+P DNLIPCKEAGLK
Sbjct: 126 TNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLK 185
Query: 243 FSKGEILQIVNREDPNWWQASHVKEGGS---AGLIPSQFLEEKRKAFVRRDWDNSGPFCG 299
F+ G+I+QI+N++D NWWQ EG S AGLIPS L+E R A + + + P C
Sbjct: 186 FATGDIIQIINKDDSNWWQGR--VEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCS 243
Query: 300 TISSKKKKKMMYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFI 359
KKK K YL ++ FD+ ++ YEEV ++P F+RKTLVLIGA GVGR +KN +
Sbjct: 244 PFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALL 303
Query: 360 VLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKI 419
NP +F VP+T+R PR+ E+DG+ Y F+S EM +I A ++LE G Y+GN++GTK
Sbjct: 304 SQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKF 363
Query: 420 DSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTK 479
+++ ++ + + ILD+ PQ LK++RT+E P++VFIA D G T+
Sbjct: 364 ETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAP-------------TDQGTQTE 410
Query: 480 LLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWV 539
L L+K +S I+ Y HYFDL ++N+ +D+ +KLQ A ++ PQWVP+SWV
Sbjct: 411 AL--QQLQK---DSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWV 465
Query: 540 Y 540
Y
Sbjct: 466 Y 466
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 348 bits (892), Expect = 9e-96
Identities = 194/541 (35%), Positives = 313/541 (57%), Gaps = 34/541 (6%)
Query: 21 DLIFLKGIMENPIVKSLAKAHERLEDSKLEA-----VSDNNLELVNEILEDITPLINVDE 75
D+ L +++N ++ K H + +A + N +L E+ + P+ + +
Sbjct: 146 DISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEG 205
Query: 76 NVAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNNSSINNQLLPVDAIRILGIHK 135
EL +L PH Q+LL AHD VA + P + E SI + ++I+ I K
Sbjct: 206 Q--ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY--GGETVKIVRIEK 261
Query: 136 RAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELL 194
PLG T R E + ++I+RI+ GG ++ GLLH GD + E+NG E+ G + E+ +LL
Sbjct: 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
Query: 195 KNISGSVTLKILPSYRDTITPQQ---VFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQI 251
++ G++T ++PS + P + + VK HFDY+P +D +PC+E GL F KG+IL +
Sbjct: 322 SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHV 381
Query: 252 VNREDPNWWQASHVKEGGS-----AGLIPSQFLEEKRKAFVRRDWDNSGP------FCGT 300
+++EDPNWWQA +EG AGL+P + +++R+A + ++ P +C
Sbjct: 382 ISQEDPNWWQA--YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAK 439
Query: 301 ISSKKKKKMMYLTTRNAEFDRHEIQIYEEVA--KMPPFQRKTLVLIGAQGVGRRSLKNRF 358
+ KK+KK++Y +N ++D EI YEE++ P +++ ++LIG Q G+ L+ R
Sbjct: 440 KNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRL 499
Query: 359 IVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTK 418
+ RF + VP T+R R+ E G+ Y FVSR EADI AGK++EHGE+E NLYGT
Sbjct: 500 MNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTS 559
Query: 419 IDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITT 478
IDS+ +V+ +G+ C+L + Q+LK LR S+ PY++FIA P E LRA+ + G
Sbjct: 560 IDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRAL---LAKEGKNP 616
Query: 479 KLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISW 538
K +L++ ++++ +++ HYFD I+N +LDKA+++L I KL EPQWVP +W
Sbjct: 617 K---PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTW 673
Query: 539 V 539
+
Sbjct: 674 L 674
>gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]
Length = 576
Score = 343 bits (879), Expect = 3e-94
Identities = 202/557 (36%), Positives = 310/557 (55%), Gaps = 52/557 (9%)
Query: 21 DLIFLKGIMENPIVKSLAKAHERL---EDSKLEAVSDNNLELVNEILEDIT--PLINVDE 75
DL FL + + SL K HE+L E + L +++ E++ PL +
Sbjct: 34 DLTFLWDMFGEKSLHSLVKIHEKLHYYEKQSPVPILHGAAALADDLAEELQNKPL---NS 90
Query: 76 NVAELVGILKEPHFQSLLEAHDIVASKCYDS--PPSSPEMNNSSINNQLLPVDAIRILGI 133
+ EL+ +L +P+ ++LL HD VA K YD PP ++++ D+++I+ +
Sbjct: 91 EIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEE--------DSVKIIRL 142
Query: 134 HKRAGEPLGVTFRVENND--LVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNN-PKEL 190
K EPLG T + + +++ARI+ GG DR GL+HVGD ++EVNG V + P+E+
Sbjct: 143 VKNR-EPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEI 201
Query: 191 QELLKNISGSVTLKILPSYRDTITPQQ--VFVKCHFDYNPYNDNLIPCKEAGLKFSKGEI 248
++L G++T KI+P ++ ++ +F+K FDYNP D IPCKEAGL F KG+I
Sbjct: 202 IQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDI 261
Query: 249 LQIVNREDPNWWQASHVKEGGS-AGLIPSQFLEEKRKAFVRRDW----------DNSG-- 295
LQI++++D WWQA H + AGLIPS+ +E+R A R + +SG
Sbjct: 262 LQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFR 321
Query: 296 -PFCGTISSKKKKKMMYLTTRNAEFDRHEIQIYEEVAKMPPFQRKT------LVLIGAQG 348
F + KK K MY ++ ++D ++ YEEV P++R+T +VL+G G
Sbjct: 322 KSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVT---PYRRQTNEKYRLVVLVGPVG 378
Query: 349 VGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHG 408
VG LK + ++ + +G TVP T+R R E DG Y F+S+ E D++ K++E+G
Sbjct: 379 VGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYG 438
Query: 409 EYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMH 468
EY+ N YGT IDS+ V+ + C+LDV P +K LRT EF PYV+FI P +E LR
Sbjct: 439 EYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETR 498
Query: 469 K-----AVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTA 523
K + D K T+ D ++ + + ++ Y H FD IIIND+L AF +L+T
Sbjct: 499 KNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTT 558
Query: 524 IEKLRMEPQWVPISWVY 540
+KL E WVP+SW++
Sbjct: 559 FDKLETETHWVPVSWLH 575
>gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
Length = 585
Score = 304 bits (778), Expect = 2e-82
Identities = 193/575 (33%), Positives = 299/575 (52%), Gaps = 60/575 (10%)
Query: 12 PSSTGAEEIDLIFLKGIMENPIVKSLAKAHERL---EDSKLEAVSDNNLELVNEILEDIT 68
P S EE+ FL+ + + L K HE+L E V + + L +++E++
Sbjct: 23 PDSNHKEEMG--FLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQ 80
Query: 69 PLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSP-PSSPEMNNSSINNQLLPVDA 127
+V + EL+ +L PH +++L HD VA K +D P P+ + + + +
Sbjct: 81 AA-SVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEE-----S 134
Query: 128 IRILGIHKRAGEPLGVTFRVENND--LVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-G 184
++I+ + K EPLG T R + + +V+ARI+ GG DR GL+HVGD ++EVNG V
Sbjct: 135 VKIVRLVKNK-EPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLH 193
Query: 185 NNPKELQELLKNISGSVTLKILPSYR--DTITPQQVFVKCHFDYNPYNDNLIPCKEAGLK 242
P E+ ++L GS+TLKI+P+ + D + +VF++ F YNP D IPC+EAGL
Sbjct: 194 KRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLP 253
Query: 243 FSKGEILQIVNREDPNWWQASHVKEGG-SAGLIPSQFLEEKRKAFVRRDWDNSGPFC--- 298
F + ++L++V+++DP WWQA V + AGLIPS+ +E+R ++ R P
Sbjct: 254 FQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRK 313
Query: 299 ---------GTISSKKKKKMMYLTTRNAEF--------------------DRHEIQIYEE 329
T + K Y+ F + E+ YEE
Sbjct: 314 PPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEE 373
Query: 330 VAK---MPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQA 386
VA+ P + + +VLIG+ G LK + + NP FG VP T+R + EK+G
Sbjct: 374 VARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVE 433
Query: 387 YKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRT 446
Y FVS+ EAD+ K+LEHGEY+ NLYGT +++I V+ + C++DV P+ALK LRT
Sbjct: 434 YHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRT 493
Query: 447 SEFMPYVVFI--AAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYF 504
SEF PY++F+ A E M A D T D ++ +A I R Y H
Sbjct: 494 SEFKPYIIFVKPAIQEKRKTPPMSPACED----TAAPFDEQQQEMAASAAFIDRHYGHLV 549
Query: 505 DLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWV 539
D +++ ++L A+ +L+ +EKL + WVP+SWV
Sbjct: 550 DAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWV 584
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 171 bits (433), Expect = 2e-42
Identities = 138/491 (28%), Positives = 219/491 (44%), Gaps = 61/491 (12%)
Query: 88 HFQSLLEAHDIVASKCYDSPPSSPEMNNSSINNQLLPVDAI----RILGIHKRA-GEPLG 142
H SL + + Y +PP P S I +L + R + +HK + G
Sbjct: 340 HNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFN 399
Query: 143 VTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNNPKE-LQELLKNISGSV 201
+ + + ++ IL GG D G L GD I VNG + N E LK SV
Sbjct: 400 IVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSV 459
Query: 202 TLKILPSYRD------------------------------TITPQQVFVKCHFDYNPYND 231
T I+ YR T + ++V+ FDY+ D
Sbjct: 460 T--IVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRD 517
Query: 232 NLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQFLEEKRKAFVR 288
+ +P + GL FS G+IL ++N D WWQA V G + G+IPS+ EK++ R
Sbjct: 518 SCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKER-AR 574
Query: 289 RDWDNSGPFCGTISSKKKKKMM---YLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIG 345
G I S + + Y +N + I YE V + + ++++G
Sbjct: 575 LKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGQEDAILSYEPVTRQEIHYARPVIILG 634
Query: 346 AQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFV-SRSEMEADIKAGKY 404
+ + + I P +FG+ VP T+R R++E DGQ Y FV SR +ME DI+ K+
Sbjct: 635 PM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKF 691
Query: 405 LEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETL 464
+E G++ NLYGT I S+ V + G+ CILDV+ A+K L+ ++ P +FI +E L
Sbjct: 692 IEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEAL 751
Query: 465 RAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAI 524
M++ T K D++ ++++ + YF I+ D+L++ + K++ I
Sbjct: 752 MEMNRR----------QTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQII 801
Query: 525 EKLRMEPQWVP 535
E WVP
Sbjct: 802 EDQSGHYIWVP 812
Score = 33.5 bits (75), Expect = 0.51
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 149 NNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGN-NPKELQELLKNISGSVTLKI 205
+N + I +I+ GG + G L +GD + VN + + +E LKN S V LK+
Sbjct: 252 DNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKV 309
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 167 bits (424), Expect = 2e-41
Identities = 127/445 (28%), Positives = 209/445 (46%), Gaps = 76/445 (17%)
Query: 148 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISGSVTLKIL 206
+ + ++ IL GG D G L GD I VNG ++ G + ++ LK +VT I+
Sbjct: 545 DGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVT--II 602
Query: 207 PSYRD------------------------------TITPQQVFVKCHFDYNPYNDNLIPC 236
Y+ T + ++V+ FDY+ D+ +P
Sbjct: 603 AQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPS 662
Query: 237 KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQF-LEEKRKAFVRRDWD 292
+ GL F G+IL ++N D WWQA V G + G+IPS+ +E K +A ++
Sbjct: 663 Q--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKF 720
Query: 293 NSGPFCGTISSK----KKKKMMYLTTRNAEFDRHEIQI-----------------YEEVA 331
N+ P G I SK K+K ++ +R F +++ Q YE V
Sbjct: 721 NAKP--GVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVT 778
Query: 332 KMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFV- 390
+ + ++++G + + + I P +FG+ VP T+R R+ E DG+ Y FV
Sbjct: 779 RQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVI 835
Query: 391 SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFM 450
SR +ME DI+ K++E G+Y NLYGT + S+ V + G+ CILDV+ A+K L+ ++
Sbjct: 836 SREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLY 895
Query: 451 PYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIIN 510
P +FI LE L M+K LT+ KKT D + ++++ + YF I+
Sbjct: 896 PIAIFIKPRSLEPLMEMNKR----------LTEEQAKKTYDRAIKLEQEFGEYFTAIVQG 945
Query: 511 DNLDKAFEKLQTAIEKLRMEPQWVP 535
D L+ + + + IE+ W+P
Sbjct: 946 DTLEDIYNQCKLVIEEQSGPFIWIP 970
Score = 34.7 bits (78), Expect = 0.23
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 149 NNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGN-NPKELQELLKNISGSVTLKI 205
+N + + +I+ GG + G L VGD + VN + + +E +LKN S V LK+
Sbjct: 324 DNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKV 381
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 167 bits (424), Expect = 2e-41
Identities = 127/445 (28%), Positives = 209/445 (46%), Gaps = 76/445 (17%)
Query: 148 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISGSVTLKIL 206
+ + ++ IL GG D G L GD I VNG ++ G + ++ LK +VT I+
Sbjct: 440 DGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVT--II 497
Query: 207 PSYRD------------------------------TITPQQVFVKCHFDYNPYNDNLIPC 236
Y+ T + ++V+ FDY+ D+ +P
Sbjct: 498 AQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPS 557
Query: 237 KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQF-LEEKRKAFVRRDWD 292
+ GL F G+IL ++N D WWQA V G + G+IPS+ +E K +A ++
Sbjct: 558 Q--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKF 615
Query: 293 NSGPFCGTISSK----KKKKMMYLTTRNAEFDRHEIQI-----------------YEEVA 331
N+ P G I SK K+K ++ +R F +++ Q YE V
Sbjct: 616 NAKP--GVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVT 673
Query: 332 KMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFV- 390
+ + ++++G + + + I P +FG+ VP T+R R+ E DG+ Y FV
Sbjct: 674 RQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVI 730
Query: 391 SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFM 450
SR +ME DI+ K++E G+Y NLYGT + S+ V + G+ CILDV+ A+K L+ ++
Sbjct: 731 SREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLY 790
Query: 451 PYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIIN 510
P +FI LE L M+K LT+ KKT D + ++++ + YF I+
Sbjct: 791 PIAIFIKPRSLEPLMEMNKR----------LTEEQAKKTYDRAIKLEQEFGEYFTAIVQG 840
Query: 511 DNLDKAFEKLQTAIEKLRMEPQWVP 535
D L+ + + + IE+ W+P
Sbjct: 841 DTLEDIYNQCKLVIEEQSGPFIWIP 865
Score = 34.7 bits (78), Expect = 0.23
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 149 NNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGN-NPKELQELLKNISGSVTLKI 205
+N + + +I+ GG + G L VGD + VN + + +E +LKN S V LK+
Sbjct: 219 DNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKV 276
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 164 bits (416), Expect = 1e-40
Identities = 124/427 (29%), Positives = 201/427 (47%), Gaps = 58/427 (13%)
Query: 148 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISGSVTLKIL 206
+ + ++ IL GG D G L GD I VNG ++ G + ++ LK +VT I+
Sbjct: 337 DGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVT--II 394
Query: 207 PSYRD------------------------------TITPQQVFVKCHFDYNPYNDNLIPC 236
Y+ T + ++V+ FDY+ D+ +P
Sbjct: 395 AQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPS 454
Query: 237 KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQF-LEEKRKAFVRRDWD 292
+ GL F G+IL ++N D WWQA V G + G+IPS+ +E K +A ++
Sbjct: 455 Q--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKF 512
Query: 293 NSGPFCGTISSKKKKKMMY---LTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQGV 349
N+ P G I SK + T+ I YE V + + ++++G
Sbjct: 513 NAKP--GVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPM-- 568
Query: 350 GRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFV-SRSEMEADIKAGKYLEHG 408
+ + + I P +FG+ VP T+R R+ E DG+ Y FV SR +ME DI+ K++E G
Sbjct: 569 -KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAG 627
Query: 409 EYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMH 468
+Y NLYGT + S+ V + G+ CILDV+ A+K L+ ++ P +FI LE L M+
Sbjct: 628 QYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMN 687
Query: 469 KAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLR 528
K LT+ KKT D + ++++ + YF I+ D L+ + + + IE+
Sbjct: 688 KR----------LTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQS 737
Query: 529 MEPQWVP 535
W+P
Sbjct: 738 GPFIWIP 744
Score = 34.7 bits (78), Expect = 0.23
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 149 NNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGN-NPKELQELLKNISGSVTLKI 205
+N + + +I+ GG + G L VGD + VN + + +E +LKN S V LK+
Sbjct: 168 DNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKV 225
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 158 bits (400), Expect = 1e-38
Identities = 121/432 (28%), Positives = 202/432 (46%), Gaps = 61/432 (14%)
Query: 148 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISGSVTLKIL 206
+ + I+ IL GG D G L GD I VN ++ + ++ LKN +VT I+
Sbjct: 485 DGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVT--IV 542
Query: 207 PSYRD------------------------------TITPQQVFVKCHFDYNPYNDNLIPC 236
YR T + ++V+ FDY+ D+ +P
Sbjct: 543 AQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPS 602
Query: 237 KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQF-LEEKRKAFVRRDWD 292
+ GL F G+IL ++N D WWQA V G + G+IPS+ +E+K +A ++
Sbjct: 603 Q--GLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKF 660
Query: 293 NSGPFC-GTISSKKKKKMMYLTTRNAEFDRHE-------IQIYEEVAKMPPFQRKTLVLI 344
NS G I K + T NA + YE V + + ++++
Sbjct: 661 NSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIIL 720
Query: 345 GAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFV-SRSEMEADIKAGK 403
G + + + I P +FG+ VP T+R R+ E DG+ Y FV SR +ME DI+ K
Sbjct: 721 GPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHK 777
Query: 404 YLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELET 463
++E G+Y +LYGT + S+ EV + G+ CILDV+ A+K L+ ++ P +FI +E
Sbjct: 778 FIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMEN 837
Query: 464 LRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTA 523
+ M+K LT+ +KT + + ++++ + +F I+ D L+ + +++
Sbjct: 838 IMEMNKR----------LTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQI 887
Query: 524 IEKLRMEPQWVP 535
IE+ WVP
Sbjct: 888 IEEQSGSYIWVP 899
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 149 NNDLVIARILHGGMIDRQGLLHVGDIIKEVNG---HEVGNNPKELQELLKNISGSVTLKI 205
+N + + +I+ GG + G L +GD + VN EV + +E LKN S V LK+
Sbjct: 345 DNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTH--EEAVTALKNTSDFVYLKV 402
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 158 bits (400), Expect = 1e-38
Identities = 126/457 (27%), Positives = 204/457 (44%), Gaps = 86/457 (18%)
Query: 148 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNNPKE-LQELLKNISGSVTLKIL 206
+ + ++ IL GG D G L GD I VNG + N E LK SVT I+
Sbjct: 68 DGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVT--IV 125
Query: 207 PSYRD------------------------------TITPQQVFVKCHFDYNPYNDNLIPC 236
YR T + ++V+ FDY+ D+ +P
Sbjct: 126 AQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPS 185
Query: 237 KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQF-LEEKRKAFVR--RD 290
+ GL FS G+IL ++N D WWQA V G + G+IPS+ +E+K +A ++ +
Sbjct: 186 Q--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKF 243
Query: 291 WDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHE--------------------------- 323
+G S K K+K + +R F + +
Sbjct: 244 HARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKG 303
Query: 324 ----IQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPRE 379
I YE V + + ++++G + + + I P +FG+ VP T+R R+
Sbjct: 304 QEDAILSYEPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRD 360
Query: 380 DEKDGQAYKFV-SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNP 438
+E DGQ Y FV SR +ME DI+ K++E G++ NLYGT I S+ V + G+ CILDV+
Sbjct: 361 NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG 420
Query: 439 QALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQR 498
A+K L+ ++ P +FI +E L M++ T K D++ ++++
Sbjct: 421 NAIKRLQQAQLYPIAIFIKPKSIEALMEMNRR----------QTYEQANKIYDKAMKLEQ 470
Query: 499 AYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVP 535
+ YF I+ D+L++ + K++ IE WVP
Sbjct: 471 EFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVP 507
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 158 bits (399), Expect = 1e-38
Identities = 103/328 (31%), Positives = 168/328 (51%), Gaps = 25/328 (7%)
Query: 216 QQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---G 272
+ ++V+ FDY+ D+ +P + GL F G+IL ++N D WWQA V G + G
Sbjct: 19 RSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMG 76
Query: 273 LIPSQF-LEEKRKAFVRRDWDNSGPFCGTISSKKKKKMMY---LTTRNAEFDRHEIQIYE 328
+IPS+ +E K +A ++ N+ P G I SK + T+ I YE
Sbjct: 77 VIPSKRRVERKERARLKTVKFNAKP--GVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYE 134
Query: 329 EVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYK 388
V + + ++++G + + + I P +FG+ VP T+R R+ E DG+ Y
Sbjct: 135 PVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYH 191
Query: 389 FV-SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTS 447
FV SR +ME DI+ K++E G+Y NLYGT + S+ V + G+ CILDV+ A+K L+ +
Sbjct: 192 FVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVA 251
Query: 448 EFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLI 507
+ P +FI LE L M+K LT+ KKT D + ++++ + YF I
Sbjct: 252 QLYPIAIFIKPRSLEPLMEMNKR----------LTEEQAKKTYDRAIKLEQEFGEYFTAI 301
Query: 508 IINDNLDKAFEKLQTAIEKLRMEPQWVP 535
+ D L+ + + + IE+ W+P
Sbjct: 302 VQGDTLEDIYNQCKLVIEEQSGPFIWIP 329
>gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens]
Length = 637
Score = 154 bits (388), Expect = 3e-37
Identities = 78/219 (35%), Positives = 131/219 (59%), Gaps = 7/219 (3%)
Query: 327 YEEVAKM---PPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKD 383
YEEV + P + + +VL+G GVG L+ + I NP+ F + VP T+R + E +
Sbjct: 413 YEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMN 472
Query: 384 GQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKV 443
G+ Y +VS+ E I + + LE+GEY+G+LYGT +D++ V+ G+ C++D+ PQ ++
Sbjct: 473 GREYHYVSKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQG 532
Query: 444 LRTSEFMPYVVFIAAPELETL---RAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAY 500
+RT E PYV+FI + + R K + D + K D DL++ + + R++ +
Sbjct: 533 VRTHELKPYVIFIKPSNMRCMKQSRKNAKVITDYYVDMK-FKDEDLQEMENLAQRMETQF 591
Query: 501 NHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWV 539
+FD +I+ND+L A +L +AI+K + EPQWVP +W+
Sbjct: 592 GQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWI 630
Score = 140 bits (354), Expect = 2e-33
Identities = 91/268 (33%), Positives = 156/268 (58%), Gaps = 16/268 (5%)
Query: 25 LKGIMENPIVKSLAKAHERLED---SKLEAVSDNNLELVNEILEDITPLINVDENVAELV 81
L ++ +P +++L K ++ L++ KL + + L E++E + E + EL
Sbjct: 53 LYDLLHSPWLQALLKIYDCLQEFKEKKLVPATPHAQVLSYEVVELLRETPTSPE-IQELR 111
Query: 82 GILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNNSSINNQLLPVDAIRILGIHKRAGEPL 141
+L+ PHF++LL AHD +A K D P P + ++ ++ +A+RI+ + K +PL
Sbjct: 112 QMLQAPHFKALLSAHDTIAQK--DFEPLLPPLPDNIPESE----EAMRIVCLVKNQ-QPL 164
Query: 142 GVTFRVEN--NDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNIS 198
G T + D+++ARI+HGG+ +R GLL+ GD + EVNG V G +P+++ +L
Sbjct: 165 GATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSR 224
Query: 199 GSVTLKILPSYRDTITPQQ-VFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDP 257
G++ K++P + QQ V+V+ +Y P D IPC +AGL F KG+ILQIV++ D
Sbjct: 225 GTIMFKVVPVSDPPVNSQQMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIVDQNDA 284
Query: 258 NWWQASHVKEGGS-AGLIPSQFLEEKRK 284
WWQA + + + AGL+PS L ++++
Sbjct: 285 LWWQARKISDPATCAGLVPSNHLLKRKQ 312
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 152 bits (385), Expect = 6e-37
Identities = 121/454 (26%), Positives = 208/454 (45%), Gaps = 83/454 (18%)
Query: 148 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISGSVTLKIL 206
+ + I+ IL GG D G L GD I VN ++ + ++ LKN +VT I+
Sbjct: 485 DGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVT--IV 542
Query: 207 PSYRD------------------------------TITPQQVFVKCHFDYNPYNDNLIPC 236
YR T + ++V+ FDY+ D+ +P
Sbjct: 543 AQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPS 602
Query: 237 KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQF-LEEKRKAFVRRDWD 292
+ GL F G+IL ++N D WWQA V G + G+IPS+ +E+K +A ++
Sbjct: 603 Q--GLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKF 660
Query: 293 NSGPFC-GTISSKKKKKMMYLTT------------RNAEFDRHE---------------- 323
NS G + K+KK ++ ++ D+H
Sbjct: 661 NSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHVTSNASDSESSYRGQEE 720
Query: 324 -IQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEK 382
+ YE V + + ++++G + + + I P +FG+ VP T+R R+ E
Sbjct: 721 YVLSYEPVNQQEVNYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEV 777
Query: 383 DGQAYKFV-SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQAL 441
DG+ Y FV SR +ME DI+ K++E G+Y +LYGT + S+ EV + G+ CILDV+ A+
Sbjct: 778 DGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAI 837
Query: 442 KVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYN 501
K L+ ++ P +FI +E + M+K LT+ +KT + + ++++ +
Sbjct: 838 KRLQIAQLYPISIFIKPKSMENIMEMNKR----------LTEEQARKTFERAMKLEQEFT 887
Query: 502 HYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVP 535
+F I+ D L+ + +++ IE+ WVP
Sbjct: 888 EHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVP 921
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 149 NNDLVIARILHGGMIDRQGLLHVGDIIKEVNG---HEVGNNPKELQELLKNISGSVTLKI 205
+N + + +I+ GG + G L +GD + VN EV + +E LKN S V LK+
Sbjct: 345 DNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTH--EEAVTALKNTSDFVYLKV 402
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 152 bits (384), Expect = 7e-37
Identities = 126/468 (26%), Positives = 208/468 (44%), Gaps = 76/468 (16%)
Query: 108 PSSPEMNNSSINNQL----LPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMI 163
P+SP + + L +P + RI+ G + + + I+ IL GG
Sbjct: 331 PTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPA 390
Query: 164 DRQGLLHVGDIIKEVNGHEVGNNPKELQEL-LKNISGSVTL------------------- 203
D G L GD I VNG ++ N E + LKN +VT+
Sbjct: 391 DLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDL 450
Query: 204 --KILPSYRDTIT------PQQVF-VKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNR 254
+++ S + T P++ F ++ FDY+ D L F G++L +++
Sbjct: 451 REQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKD--CGFLSQALSFRFGDVLHVIDA 508
Query: 255 EDPNWWQASHV---KEGGSAGLIPSQFLEEKRK--AFVRRDWDNSGPFCGTISSKKKKKM 309
D WWQA V E G IPS+ E+R+ +DW +S G S
Sbjct: 509 SDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDS------ 562
Query: 310 MYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIG-AQGVGRRSLKNRFIVLNPTRFGT 368
+ YE V +M + ++++G + L + F P +FG+
Sbjct: 563 --------------VLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEF----PDKFGS 604
Query: 369 TVPFTSRKPREDEKDGQAYKFVS-RSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQ 427
VP T+R RE E DG+ Y FVS R +ME DI+A K++E G+Y +LYGT + S+ EV +
Sbjct: 605 CVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAE 664
Query: 428 TGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLK 487
G+ CILDV+ A++ L+ + P +FI LE + ++K + T+ +
Sbjct: 665 QGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI----------TEEQAR 714
Query: 488 KTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVP 535
K D + ++++ + F I+ D+ ++ + K++ IE L WVP
Sbjct: 715 KAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVP 762
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 152 bits (384), Expect = 7e-37
Identities = 126/468 (26%), Positives = 208/468 (44%), Gaps = 76/468 (16%)
Query: 108 PSSPEMNNSSINNQL----LPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMI 163
P+SP + + L +P + RI+ G + + + I+ IL GG
Sbjct: 285 PTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPA 344
Query: 164 DRQGLLHVGDIIKEVNGHEVGNNPKELQEL-LKNISGSVTL------------------- 203
D G L GD I VNG ++ N E + LKN +VT+
Sbjct: 345 DLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDL 404
Query: 204 --KILPSYRDTIT------PQQVF-VKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNR 254
+++ S + T P++ F ++ FDY+ D L F G++L +++
Sbjct: 405 REQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKD--CGFLSQALSFRFGDVLHVIDA 462
Query: 255 EDPNWWQASHV---KEGGSAGLIPSQFLEEKRK--AFVRRDWDNSGPFCGTISSKKKKKM 309
D WWQA V E G IPS+ E+R+ +DW +S G S
Sbjct: 463 SDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDS------ 516
Query: 310 MYLTTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIG-AQGVGRRSLKNRFIVLNPTRFGT 368
+ YE V +M + ++++G + L + F P +FG+
Sbjct: 517 --------------VLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEF----PDKFGS 558
Query: 369 TVPFTSRKPREDEKDGQAYKFVS-RSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQ 427
VP T+R RE E DG+ Y FVS R +ME DI+A K++E G+Y +LYGT + S+ EV +
Sbjct: 559 CVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAE 618
Query: 428 TGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLK 487
G+ CILDV+ A++ L+ + P +FI LE + ++K + T+ +
Sbjct: 619 QGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI----------TEEQAR 668
Query: 488 KTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVP 535
K D + ++++ + F I+ D+ ++ + K++ IE L WVP
Sbjct: 669 KAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVP 716
>gi|226874833 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 107 bits (268), Expect = 2e-23
Identities = 58/192 (30%), Positives = 105/192 (54%), Gaps = 13/192 (6%)
Query: 339 KTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEAD 398
+ +VL G G G+ +L R + + FG +V T+R PR E++G+ Y FV+R M+ D
Sbjct: 5 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQRD 64
Query: 399 IKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAA 458
I AG ++EH E+ GNLYGT ++ V R C+LDV+ Q ++ ++ ++ P + +
Sbjct: 65 IAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQP 124
Query: 459 PEL----ETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLD 514
P L + LR + ++ + +D++ + + FD++IIND+LD
Sbjct: 125 PSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPG---------LFDVVIINDSLD 175
Query: 515 KAFEKLQTAIEK 526
+A+ +L+ A+ +
Sbjct: 176 QAYAELKEALSE 187
>gi|226874831 guanylate kinase 1 isoform a [Homo sapiens]
Length = 218
Score = 107 bits (268), Expect = 2e-23
Identities = 58/192 (30%), Positives = 105/192 (54%), Gaps = 13/192 (6%)
Query: 339 KTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEAD 398
+ +VL G G G+ +L R + + FG +V T+R PR E++G+ Y FV+R M+ D
Sbjct: 26 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQRD 85
Query: 399 IKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAA 458
I AG ++EH E+ GNLYGT ++ V R C+LDV+ Q ++ ++ ++ P + +
Sbjct: 86 IAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQP 145
Query: 459 PEL----ETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLD 514
P L + LR + ++ + +D++ + + FD++IIND+LD
Sbjct: 146 PSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPG---------LFDVVIINDSLD 196
Query: 515 KAFEKLQTAIEK 526
+A+ +L+ A+ +
Sbjct: 197 QAYAELKEALSE 208
>gi|4504221 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 107 bits (268), Expect = 2e-23
Identities = 58/192 (30%), Positives = 105/192 (54%), Gaps = 13/192 (6%)
Query: 339 KTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEAD 398
+ +VL G G G+ +L R + + FG +V T+R PR E++G+ Y FV+R M+ D
Sbjct: 5 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQRD 64
Query: 399 IKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAA 458
I AG ++EH E+ GNLYGT ++ V R C+LDV+ Q ++ ++ ++ P + +
Sbjct: 65 IAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQP 124
Query: 459 PEL----ETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLD 514
P L + LR + ++ + +D++ + + FD++IIND+LD
Sbjct: 125 PSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPG---------LFDVVIINDSLD 175
Query: 515 KAFEKLQTAIEK 526
+A+ +L+ A+ +
Sbjct: 176 QAYAELKEALSE 187
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 12/190 (6%)
Query: 341 LVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIK 400
L+L G + G+R L +R T F T+R P E D Y F+S+ + +
Sbjct: 417 LILAGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQDVFDEMVN 476
Query: 401 AGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPE 460
GK++ Y + YG D++ + + G + + + ++ L+ S F P + +
Sbjct: 477 MGKFILTFSYGNHKYGLNRDTVEGIARDGLASCIHMEIEGVRSLKYSYFEPRYILVV--- 533
Query: 461 LETLRAMHKAVVDAGITTK-LLTDSDLK---KTVDESARIQRAYNHYFDLIIINDNLDKA 516
M+K + + K L + ++++ VD +I + + YFD +I D+LD A
Sbjct: 534 -----PMNKEKYEGYLRRKGLFSRAEIEFAVSRVDLYIKINQNFPGYFDEVINADDLDVA 588
Query: 517 FEKLQTAIEK 526
++KL I +
Sbjct: 589 YQKLSQLIRE 598
>gi|10092691 tight junction protein 3 [Homo sapiens]
Length = 952
Score = 54.7 bits (130), Expect = 2e-07
Identities = 80/426 (18%), Positives = 168/426 (39%), Gaps = 75/426 (17%)
Query: 138 GEPLGVTFRVENN-DLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGN-NPKELQELLK 195
G+ +G+ N+ + ++ + G D QG+ GD I +VN N +E + L
Sbjct: 422 GKSIGLRLAGGNDVGIFVSGVQAGSPADGQGIQE-GDQILQVNDVPFQNLTREEAVQFLL 480
Query: 196 NISGSVTLKILPSYRDTITPQQV--------FVKCHFDYNPYNDNLIPCKEAGLKFSKGE 247
+ ++++ + I + V +++ HF+ L P +GL F++G+
Sbjct: 481 GLPPGEEMELVTQRKQDIFWKMVQSRVGDSFYIRTHFE-------LEPSPPSGLGFTRGD 533
Query: 248 ILQIVNREDPNWWQASHVKEGG-------------SAGLIPSQFLEEKR---KAFVRRDW 291
+ +++ P Q SH + G G+IP+Q E+ +A R
Sbjct: 534 VFHVLDTLHPGPGQ-SHARGGHWLAVRMGRDLREQERGIIPNQSRAEQLASLEAAQRAVG 592
Query: 292 DNSGPFCGTISSKKKKKMMYL---TTRNAEFDRHEIQIYEEVAKMPPFQRKTLVLIGAQG 348
G G+ + + ++ L + + R ++ + PP++R L
Sbjct: 593 VGPGSSAGSNARAEFWRLRGLRRGAKKTTQRSREDLSALTRQGRYPPYERVVL------- 645
Query: 349 VGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHG 408
S K ++L P T+ P + E + VSR++ + I
Sbjct: 646 -REASFKRPVVILGPVADIAMQKLTAEMPDQFE----IAETVSRTDSPSKI--------- 691
Query: 409 EYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMH 468
K+D++ + + + +LDV P A++ L ++ P VVF L+A+
Sbjct: 692 --------IKLDTVRVIAEKDKHALLDVTPSAIERLNYVQYYPIVVFFIPESRPALKALR 743
Query: 469 KAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLII-INDNLDKAFEKLQTAIEKL 527
+ + A + ++ ++ ++++ +H F I +N D +++L+ I +
Sbjct: 744 QWLAPA-------SRRSTRRLYAQAQKLRKHSSHLFTATIPLNGTSDTWYQELKAIIREQ 796
Query: 528 RMEPQW 533
+ P W
Sbjct: 797 QTRPIW 802
Score = 29.3 bits (64), Expect = 9.6
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 121 QLLPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNG 180
Q+ PV ++ + +R E GV + + I I G+ R L GD+I ++NG
Sbjct: 208 QMKPVKSVLV---KRRDSEEFGVKL---GSQIFIKHITDSGLAARHRGLQEGDLILQING 261
Query: 181 HEVGN-NPKELQELLKNISGSVTLKIL 206
N + + + L++ G ++L +L
Sbjct: 262 VSSQNLSLNDTRRLIEKSEGKLSLLVL 288
>gi|42518065 tight junction protein 2 (zona occludens 2) isoform 2
[Homo sapiens]
Length = 1043
Score = 50.1 bits (118), Expect = 5e-06
Identities = 78/414 (18%), Positives = 163/414 (39%), Gaps = 59/414 (14%)
Query: 136 RAGEPLGVTFRVENN-DLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNNPKE--LQE 192
+ G+ +G+ N+ + +A I G +++GL GD I +VN + +E +
Sbjct: 516 KKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQE-GDQILKVNTQDFRGLVREDAVLY 574
Query: 193 LLKNISGSVTLKILPS----YRDTIT---PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSK 245
LL+ G + + S YRD + F++ HF+ L F++
Sbjct: 575 LLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETPQ-------SLAFTR 627
Query: 246 GEILQIVNREDPNW---WQASHVKEGGSAGLIPSQFLEEKRKAFVRRDWDNSGPFCGTIS 302
GE+ ++V+ W A + GLIP++ E+ + DN+G
Sbjct: 628 GEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWR 687
Query: 303 SKKKKKMMYLTTRNAEFDRHEIQIYEEVA-KMPPFQRKTLVLIGAQGVGRRSLKNRFIVL 361
+ ++ + +N R ++ V+ K P ++R L R + R +VL
Sbjct: 688 MRGQRSGV---KKNLRKSREDLTAVVSVSTKFPAYERVLL---------REAGFKRPVVL 735
Query: 362 NPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDS 421
FG K + D + ++ G ++++
Sbjct: 736 ----FGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGV-------------VRLNT 778
Query: 422 ILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLL 481
+ ++++ + +LDV P+A+ +L +++ P V+F + ++ M + +
Sbjct: 779 VRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRL-------NPT 831
Query: 482 TDSDLKKTVDESARIQRAYNHYFDLII-INDNLDKAFEKLQTAIEKLRMEPQWV 534
++ +K D++ ++++ H F I +N D F L+ I+ + E WV
Sbjct: 832 SNKSSRKLFDQANKLKKTCAHLFTATINLNSANDSWFGSLKDTIQHQQGEAVWV 885
Score = 34.3 bits (77), Expect = 0.30
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Query: 128 IRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGN-N 186
I +L + RA E G+ + + + + G+ + G LH GDII ++NG N +
Sbjct: 306 IGVLLMKSRANEEYGLRL---GSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMS 362
Query: 187 PKELQELLKNISGSVTLKILPSYRDTI 213
+ ++L++ G + L +L + T+
Sbjct: 363 LTDARKLIEKSRGKLQLVVLRDSQQTL 389
>gi|42518070 tight junction protein 2 (zona occludens 2) isoform 1
[Homo sapiens]
Length = 1190
Score = 50.1 bits (118), Expect = 5e-06
Identities = 78/414 (18%), Positives = 163/414 (39%), Gaps = 59/414 (14%)
Query: 136 RAGEPLGVTFRVENN-DLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNNPKE--LQE 192
+ G+ +G+ N+ + +A I G +++GL GD I +VN + +E +
Sbjct: 516 KKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQE-GDQILKVNTQDFRGLVREDAVLY 574
Query: 193 LLKNISGSVTLKILPS----YRDTIT---PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSK 245
LL+ G + + S YRD + F++ HF+ L F++
Sbjct: 575 LLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETPQ-------SLAFTR 627
Query: 246 GEILQIVNREDPNW---WQASHVKEGGSAGLIPSQFLEEKRKAFVRRDWDNSGPFCGTIS 302
GE+ ++V+ W A + GLIP++ E+ + DN+G
Sbjct: 628 GEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWR 687
Query: 303 SKKKKKMMYLTTRNAEFDRHEIQIYEEVA-KMPPFQRKTLVLIGAQGVGRRSLKNRFIVL 361
+ ++ + +N R ++ V+ K P ++R L R + R +VL
Sbjct: 688 MRGQRSGV---KKNLRKSREDLTAVVSVSTKFPAYERVLL---------REAGFKRPVVL 735
Query: 362 NPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDS 421
FG K + D + ++ G ++++
Sbjct: 736 ----FGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGV-------------VRLNT 778
Query: 422 ILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLL 481
+ ++++ + +LDV P+A+ +L +++ P V+F + ++ M + +
Sbjct: 779 VRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRL-------NPT 831
Query: 482 TDSDLKKTVDESARIQRAYNHYFDLII-INDNLDKAFEKLQTAIEKLRMEPQWV 534
++ +K D++ ++++ H F I +N D F L+ I+ + E WV
Sbjct: 832 SNKSSRKLFDQANKLKKTCAHLFTATINLNSANDSWFGSLKDTIQHQQGEAVWV 885
Score = 34.3 bits (77), Expect = 0.30
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Query: 128 IRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGN-N 186
I +L + RA E G+ + + + + G+ + G LH GDII ++NG N +
Sbjct: 306 IGVLLMKSRANEEYGLRL---GSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMS 362
Query: 187 PKELQELLKNISGSVTLKILPSYRDTI 213
+ ++L++ G + L +L + T+
Sbjct: 363 LTDARKLIEKSRGKLQLVVLRDSQQTL 389
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 49.7 bits (117), Expect = 7e-06
Identities = 29/145 (20%), Positives = 65/145 (44%), Gaps = 4/145 (2%)
Query: 391 SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFM 450
S+ +E +K ++++ G+ T + SI E+ + R C+LD+ P A++ L
Sbjct: 1775 SQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIY 1834
Query: 451 PYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIIN 510
P V+FI + ++ D +T K+ + + ++++ Y+ YF +I
Sbjct: 1835 PIVIFIHYKSAKHIKEQR----DPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQG 1890
Query: 511 DNLDKAFEKLQTAIEKLRMEPQWVP 535
L ++ + + + + W+P
Sbjct: 1891 GALSSICTQILAMVNQEQNKVLWIP 1915
Score = 33.9 bits (76), Expect = 0.39
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 150 NDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNNP-KELQELLKNISGSVTLKIL 206
N + A +L G ++G L VGD I +NG + N E + LL++ S+TL +L
Sbjct: 736 NGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLL 793
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 49.7 bits (117), Expect = 7e-06
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 19/106 (17%)
Query: 224 FDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLIPSQFLEEKR 283
+DY ND+ L F+KG+I+ ++N+EDP+WW+ + G GL PS +++
Sbjct: 1164 YDYTAQNDD-------ELAFNKGQIINVLNKEDPDWWKG---EVNGQVGLFPSNYVK--- 1210
Query: 284 KAFVRRDWDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHEIQIYEE 329
+ D D S +C S M+ T R + HE+ + EE
Sbjct: 1211 ---LTTDMDPSQQWC---SDLHLLDMLTPTERKRQGYIHELIVTEE 1250
>gi|218505835 membrane-associated guanylate kinase-related 3
isoform 1 [Homo sapiens]
Length = 1481
Score = 49.3 bits (116), Expect = 9e-06
Identities = 23/58 (39%), Positives = 34/58 (58%)
Query: 360 VLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGT 417
V+ + T+P T+R PR+ E G Y F+S + +A ++G LE G Y+GN YGT
Sbjct: 133 VIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGTYDGNFYGT 190
Score = 36.2 bits (82), Expect = 0.078
Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 110 SPEMNNSSINNQLLPVDAIRILGIHKRAGEPLGVTFRVENNDLV-------IARILHGGM 162
SP +N + + + P + ++ + ++ E G N I R++ G
Sbjct: 832 SPRLNRAEVPARPAPQEPYDVV-LQRKENEGFGFVILTSKNKPPPGVIPHKIGRVIEGSP 890
Query: 163 IDRQGLLHVGDIIKEVNGHEVGN-NPKELQELLKNISGSVTLKIL 206
DR G L VGD I VNG + + + +L+K+ +VTL ++
Sbjct: 891 ADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVI 935
Score = 30.0 bits (66), Expect = 5.6
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 149 NNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISGSVTLKILP 207
N L I R+ G + G +HVGD I E+NG G EL++ V L + P
Sbjct: 1042 NMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRP 1101
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,742,876
Number of Sequences: 37866
Number of extensions: 874610
Number of successful extensions: 2977
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 2636
Number of HSP's gapped (non-prelim): 353
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.