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Search of human proteins with 21361329
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo
sapiens]
(295 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo s... 600 e-172
gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo s... 586 e-168
gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo s... 493 e-140
gi|5730019 peropsin [Homo sapiens] 128 7e-30
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 110 1e-24
gi|38678524 opsin 5 isoform 1 [Homo sapiens] 103 1e-22
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 102 5e-22
gi|71999131 opsin 3 [Homo sapiens] 100 1e-21
gi|4506527 rhodopsin [Homo sapiens] 95 8e-20
gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [H... 71 1e-12
gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo ... 71 1e-12
gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sa... 69 5e-12
gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 61 1e-09
gi|5174593 melatonin receptor 1A [Homo sapiens] 60 2e-09
gi|71999146 opsin 5 isoform 2 [Homo sapiens] 57 2e-08
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 57 3e-08
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 57 3e-08
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 57 3e-08
gi|5174595 melatonin receptor 1B [Homo sapiens] 55 6e-08
gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s... 55 7e-08
gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens] 53 3e-07
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 53 4e-07
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 52 6e-07
gi|7669548 tachykinin receptor 3 [Homo sapiens] 52 8e-07
gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens] 52 8e-07
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 50 2e-06
gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo sap... 49 4e-06
gi|31881792 leukotriene B4 receptor [Homo sapiens] 49 5e-06
gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom... 49 5e-06
gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo... 49 5e-06
>gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo
sapiens]
Length = 295
Score = 600 bits (1547), Expect = e-172
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
Sbjct: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
Query: 61 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 120
ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
Sbjct: 61 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 120
Query: 121 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 180
YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
Sbjct: 121 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 180
Query: 181 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI 240
LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
Sbjct: 181 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI 240
Query: 241 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 295
ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Sbjct: 241 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 295
>gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo
sapiens]
Length = 291
Score = 586 bits (1511), Expect = e-168
Identities = 291/295 (98%), Positives = 291/295 (98%), Gaps = 4/295 (1%)
Query: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
Sbjct: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
Query: 61 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 120
ADSGISLNALVAATSSLLR RWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
Sbjct: 61 ADSGISLNALVAATSSLLR----RWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 116
Query: 121 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 180
YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
Sbjct: 117 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 176
Query: 181 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI 240
LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
Sbjct: 177 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI 236
Query: 241 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 295
ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Sbjct: 237 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 291
>gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo
sapiens]
Length = 253
Score = 493 bits (1269), Expect = e-140
Identities = 253/295 (85%), Positives = 253/295 (85%), Gaps = 42/295 (14%)
Query: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
Sbjct: 1 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL 60
Query: 61 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 120
ADSGISLNALVAATSSLLR RWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
Sbjct: 61 ADSGISLNALVAATSSLLR----RWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH 116
Query: 121 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 180
YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
Sbjct: 117 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF 176
Query: 181 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI 240
LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQ
Sbjct: 177 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQ-------------------------- 210
Query: 241 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 295
VPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Sbjct: 211 ------------VPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK 253
>gi|5730019 peropsin [Homo sapiens]
Length = 337
Score = 128 bits (321), Expect = 7e-30
Identities = 79/290 (27%), Positives = 135/290 (46%), Gaps = 24/290 (8%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS-LNA 69
F + E V L++ + + N + + F K ELRTP + ++++LA+ D G+S +
Sbjct: 20 FSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGY 79
Query: 70 LVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRS---Q 126
++A S L + W +G GCQ + +ASI +A RY C +
Sbjct: 80 PMSAASDL----YGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRR 135
Query: 127 LAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSF 186
+ N+ + L+L W++ FWA +P++GW Y +P G CT+++ K DR+F S+ T+
Sbjct: 136 MTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIA 195
Query: 187 FNFAMPLFITITSY------------SLMEQKLGKSGHLQVNTT----LPARTLLLGWGP 230
NF +PL + Y S + L + Q++ T + L+ W P
Sbjct: 196 INFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSP 255
Query: 231 YAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGI 280
Y+I+ L+A D I P + ++ L AK N Y + N+ R +
Sbjct: 256 YSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAM 305
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 110 bits (275), Expect = 1e-24
Identities = 81/284 (28%), Positives = 132/284 (46%), Gaps = 35/284 (12%)
Query: 19 VGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLN-ALVAATSSL 77
+G V+L+ L+G+ N I++FC++ LRTP ++ +++LA++D +S A V TSSL
Sbjct: 73 LGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSL 132
Query: 78 LRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYCTRSQLAWNSAV 133
+++W +G GC+ + F G + ++S+ + AIA RY T + A
Sbjct: 133 ----YKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAA 188
Query: 134 SLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPL 193
++L VWL + W+ P GW Y E L T C+ DY ++ + F F +PL
Sbjct: 189 FVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPL 248
Query: 194 FITITSYSLMEQKLGKSG--------------------HLQVNTTLPARTLL------LG 227
I I Y + + + ++G LQ + LL L
Sbjct: 249 LIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLS 308
Query: 228 WGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYAL 271
W PY+ + L A ++P + VPA+IAK N I YA+
Sbjct: 309 WAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAI 352
>gi|38678524 opsin 5 isoform 1 [Homo sapiens]
Length = 354
Score = 103 bits (258), Expect = 1e-22
Identities = 70/276 (25%), Positives = 123/276 (44%), Gaps = 26/276 (9%)
Query: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSS 76
L G L + + N ++ + + P ++ ++LA+ D GIS+ V +
Sbjct: 34 LVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISV---VGKPFT 90
Query: 77 LLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAW---NSAV 133
++ RW +G GC+ +G+ GF S+ + A++ RY C S W A
Sbjct: 91 IISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAY 150
Query: 134 SLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFAM 191
+ +W ++FW +PL+G G Y EP GT CTLD+ ++ F+ + FF +
Sbjct: 151 ICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLL 210
Query: 192 PLFITITSY--------------SLMEQKLGKSGHLQVNTTLPARTL----LLGWGPYAI 233
P + + SY + + ++ S L++ T A + L+ W PYA+
Sbjct: 211 PTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAV 270
Query: 234 LYLYAVIADVTSISPKLQMVPALIAKMVPTINAINY 269
+ +++ SI +L +VP L+AK N I Y
Sbjct: 271 VSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIY 306
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 102 bits (253), Expect = 5e-22
Identities = 81/295 (27%), Positives = 132/295 (44%), Gaps = 46/295 (15%)
Query: 19 VGMVLLVEALSGLSLNTLTIFSFCK-----------TPELRTPCHLLVLSLALADSGISL 67
+G V+L+ L+G+ N I++FC+ + LRTP ++ +++LA++D +S
Sbjct: 73 LGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSF 132
Query: 68 N-ALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYC 122
A V TSSL +++W +G GC+ + F G + ++S+ + AIA RY
Sbjct: 133 TQAPVFFTSSL----YKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA 188
Query: 123 TRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLF 182
T + A ++L VWL + W+ P GW Y E L T C+ DY ++
Sbjct: 189 TFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTM 248
Query: 183 TMSFFNFAMPLFITITSYSLMEQKLGKSG--------------------HLQVNTTLPAR 222
+ F F +PL I I Y + + + ++G LQ +
Sbjct: 249 LLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKI 308
Query: 223 TLL------LGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYAL 271
LL L W PY+ + L A ++P + VPA+IAK N I YA+
Sbjct: 309 MLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAI 363
>gi|71999131 opsin 3 [Homo sapiens]
Length = 402
Score = 100 bits (250), Expect = 1e-21
Identities = 75/293 (25%), Positives = 123/293 (41%), Gaps = 41/293 (13%)
Query: 28 LSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRVSHRRWPY 87
L G+ N L + + K LRTP HLL+++++L+D +SL + S LR W +
Sbjct: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLR---NGWVW 109
Query: 88 GSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWA 147
+ GC GF G + + SI + +A+ RY + ++ A + ++WL S WA
Sbjct: 110 DTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWA 169
Query: 148 ALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLM---- 203
PLLGW Y + G CT+D+ D N +SF+ + +PL + Y +
Sbjct: 170 GAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSI 229
Query: 204 --------------------EQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADV 243
E+KL K L + T L+ W PY ++ V
Sbjct: 230 RMLRCVEDLQTIQVIKILKYEKKLAKMCFLMI------FTFLVCWMPYIVICFLVVNGHG 283
Query: 244 TSISPKLQMVPALIAKMVPTINAINYALG--------NEMVCRGIWQCLSPQK 288
++P + +V L AK N + Y +++C + +C P K
Sbjct: 284 HLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAK 336
>gi|4506527 rhodopsin [Homo sapiens]
Length = 348
Score = 94.7 bits (234), Expect = 8e-20
Identities = 75/281 (26%), Positives = 123/281 (43%), Gaps = 24/281 (8%)
Query: 13 ELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVA 72
+ +LA M LL+ + G +N LT++ + +LRTP + ++L+LA+AD + L
Sbjct: 36 QFSMLAAYMFLLI--VLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGF-- 91
Query: 73 ATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC---TRSQLAW 129
TS+L H + +G GC GF + ++ S +A RY C + +
Sbjct: 92 -TSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGE 150
Query: 130 NSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFF 187
N A+ V F W+ + AA PL GW Y E L C +DY K + N SF+ M
Sbjct: 151 NHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVV 210
Query: 188 NFAMPLFI----------TITSYSLMEQKLGKSGHLQVNTT----LPARTLLLGWGPYAI 233
+F +P+ I T+ + +Q+ + + T + L+ W PYA
Sbjct: 211 HFTIPMIIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYAS 270
Query: 234 LYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNE 274
+ Y ++ P +PA AK N + Y + N+
Sbjct: 271 VAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNK 311
>gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [Homo
sapiens]
Length = 364
Score = 71.2 bits (173), Expect = 1e-12
Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 24/275 (8%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
+V M+ +V ++ + N L + + K +LR P + ++++LA+AD ++A+T S+
Sbjct: 57 SVWMIFVV--IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLA---ETVIASTISV 111
Query: 78 LRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR-SQLAWNSAVSLV 136
+ + + G C G+ + + + S A I+W R+ C + +++ +++V
Sbjct: 112 VNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIV 171
Query: 137 --LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDR--NFTSFLFTMSFFNFAMP 192
F W+ +A W A P+ GW Y L T C D G S++ + P
Sbjct: 172 GIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITP 231
Query: 193 LFITITSYSLM---------EQKLGKSGH-LQVNTTLPARTLLLG----WGPYAILYLYA 238
L I + Y + +QK +S + T ++L WGPYA +A
Sbjct: 232 LSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFA 291
Query: 239 VIADVTSISPKLQMVPALIAKMVPTINAINYALGN 273
P + +PA AK N + Y N
Sbjct: 292 AANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMN 326
>gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo
sapiens]
Length = 364
Score = 71.2 bits (173), Expect = 1e-12
Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 24/275 (8%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
+V M+ +V ++ + N L + + K +LR P + ++++LA+AD ++A+T S+
Sbjct: 57 SVWMIFVV--IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLA---ETVIASTISV 111
Query: 78 LRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR-SQLAWNSAVSLV 136
+ + + G C G+ + + + S A I+W R+ C + +++ +++V
Sbjct: 112 VNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIV 171
Query: 137 --LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDR--NFTSFLFTMSFFNFAMP 192
F W+ +A W A P+ GW Y L T C D G S++ + P
Sbjct: 172 GIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITP 231
Query: 193 LFITITSYSLM---------EQKLGKSGH-LQVNTTLPARTLLLG----WGPYAILYLYA 238
L I + Y + +QK +S + T ++L WGPYA +A
Sbjct: 232 LSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFA 291
Query: 239 VIADVTSISPKLQMVPALIAKMVPTINAINYALGN 273
P + +PA AK N + Y N
Sbjct: 292 AANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMN 326
>gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo
sapiens]
Length = 364
Score = 68.9 bits (167), Expect = 5e-12
Identities = 66/277 (23%), Positives = 112/277 (40%), Gaps = 28/277 (10%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
+V M+ +V A + N L + + K +LR P + ++++LA+AD ++A+T S+
Sbjct: 57 SVWMIFVVTA--SVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLA---ETVIASTISI 111
Query: 78 LRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR-SQLAWNSAVSLV 136
+ + G C G+ + + + S A I+W R+ C + +++ +++V
Sbjct: 112 VNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIV 171
Query: 137 --LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDR--NFTSFLFTMSFFNFAMP 192
F W+ SA W A P+ GW Y L T C D G S++ + +P
Sbjct: 172 GIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIP 231
Query: 193 LFITITSY----------------SLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYL 236
L I + Y S QK K V + A + WGPY
Sbjct: 232 LAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVC--WGPYTFFAC 289
Query: 237 YAVIADVTSISPKLQMVPALIAKMVPTINAINYALGN 273
+A + P + +PA AK N + Y N
Sbjct: 290 FAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMN 326
>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
Length = 617
Score = 60.8 bits (146), Expect = 1e-09
Identities = 78/318 (24%), Positives = 128/318 (40%), Gaps = 49/318 (15%)
Query: 1 MAETSALPTGFGELE------------VLAVGMVLLVEALSGLSLNTLTIFSFCKTPELR 48
M T A+PT +G + ++ + +++ + L N++ I + K +LR
Sbjct: 1 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR 60
Query: 49 TPCHLLVLSLALADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASIC 108
++ V+SL++AD L A+ L +S W CQ GF ++ + SI
Sbjct: 61 NSGNIFVVSLSVADM---LVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIF 117
Query: 109 SSAAIAWGRYHHYCTRSQL-----AWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLG 163
+ AIA RY + C Q N+ + LV+ W+ + A LP + G +Y+P
Sbjct: 118 NIVAIAINRYCYICHSLQYERIFSVRNTCIYLVI-TWIMTVL-AVLPNMYIGTIEYDPRT 175
Query: 164 TCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKL----GKSGHLQVNTTL 219
C +Y N F T+ +F +PL I Y + K+ +G N
Sbjct: 176 YTCIFNY----LNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLA 231
Query: 220 PARTLLLGWGPYAILYLYA-------VIADVTSISPK---------LQMVPALIAKMVPT 263
R L + I L+A V+ + ++SPK L + IA
Sbjct: 232 EVRNFLT---MFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSC 288
Query: 264 INAINYALGNEMVCRGIW 281
+NA+ Y L NE R W
Sbjct: 289 LNAVIYGLLNENFRREYW 306
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 12/187 (6%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
A+ VL+ + + N L I S + +LR ++ V+SLA+AD + A+ L
Sbjct: 29 ALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVV---AIYPYPLVL 85
Query: 78 LRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC--TRSQLAWNSAVSL 135
+ + + W G CQ GF ++ + SI + IA RY + C + ++S SL
Sbjct: 86 MSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSL 145
Query: 136 --VLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPL 193
VL +WL + A LP L G Y+P CT S +++ + F+F +P+
Sbjct: 146 CYVLLIWLLT-LAAVLPNLRAGTLQYDPRIYSCTFAQSVS----SAYTIAVVVFHFLVPM 200
Query: 194 FITITSY 200
I I Y
Sbjct: 201 IIVIFCY 207
>gi|71999146 opsin 5 isoform 2 [Homo sapiens]
Length = 189
Score = 57.0 bits (136), Expect = 2e-08
Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 20/141 (14%)
Query: 149 LPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFAMPLFITITSY------ 200
+PL+G G Y EP GT CTLD+ ++ F+ + FF +P + + SY
Sbjct: 1 MPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAK 60
Query: 201 --------SLMEQKLGKSGHLQVNTTLPARTL----LLGWGPYAILYLYAVIADVTSISP 248
+ + ++ S L++ T A + L+ W PYA++ +++ SI
Sbjct: 61 VKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI 120
Query: 249 KLQMVPALIAKMVPTINAINY 269
+L +VP L+AK N I Y
Sbjct: 121 QLSVVPTLLAKSAAMYNPIIY 141
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 56.6 bits (135), Expect = 3e-08
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 10/150 (6%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL 70
+G +E + +G +L + L ++ N L + S C +LR P + L++SLALAD +S+
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALAD--LSVAVA 133
Query: 71 VAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY------HHYCTR 124
V S+ + +W +G C + ASI + I+ RY Y R
Sbjct: 134 VMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVR 193
Query: 125 SQLAWNSAVSLVLFVWLSSAFWAALPLLGW 154
++L VWL SA PL GW
Sbjct: 194 QN--GKCMAKMILSVWLLSASITLPPLFGW 221
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 56.6 bits (135), Expect = 3e-08
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 10/150 (6%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL 70
+G +E + +G +L + L ++ N L + S C +LR P + L++SLALAD +S+
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALAD--LSVAVA 133
Query: 71 VAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY------HHYCTR 124
V S+ + +W +G C + ASI + I+ RY Y R
Sbjct: 134 VMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVR 193
Query: 125 SQLAWNSAVSLVLFVWLSSAFWAALPLLGW 154
++L VWL SA PL GW
Sbjct: 194 QN--GKCMAKMILSVWLLSASITLPPLFGW 221
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 56.6 bits (135), Expect = 3e-08
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 10/150 (6%)
Query: 11 FGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNAL 70
+G +E + +G +L + L ++ N L + S C +LR P + L++SLALAD +S+
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALAD--LSVAVA 133
Query: 71 VAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY------HHYCTR 124
V S+ + +W +G C + ASI + I+ RY Y R
Sbjct: 134 VMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVR 193
Query: 125 SQLAWNSAVSLVLFVWLSSAFWAALPLLGW 154
++L VWL SA PL GW
Sbjct: 194 QN--GKCMAKMILSVWLLSASITLPPLFGW 221
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 55.5 bits (132), Expect = 6e-08
Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 14/188 (7%)
Query: 18 AVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSL 77
A+ VL+V + N L I S + +LR +L ++SLALAD + A L
Sbjct: 42 ALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVV---AFYPYPLIL 98
Query: 78 LRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC-----TRSQLAWNSA 132
+ + + W G + C+A F ++ + S+ + AIA RY + C R W++
Sbjct: 99 VAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTP 158
Query: 133 VSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMP 192
+ + L +WL + A LP G +Y+P CT + T + + +F +P
Sbjct: 159 LHICL-IWLLTVV-ALLPNFFVGSLEYDPRIYSCTFIQTAS----TQYTAAVVVIHFLLP 212
Query: 193 LFITITSY 200
+ + Y
Sbjct: 213 IAVVSFCY 220
>gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo
sapiens]
Length = 348
Score = 55.1 bits (131), Expect = 7e-08
Identities = 63/283 (22%), Positives = 116/283 (40%), Gaps = 32/283 (11%)
Query: 14 LEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAA 73
L+ +G V L+ G LN + + + + +LR P + ++++++ G L + +
Sbjct: 36 LQAAFMGTVFLI----GFPLNAMVLVATLRYKKLRQPLNYILVNVSF---GGFLLCIFSV 88
Query: 74 TSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCT---RSQLAWN 130
+ + + +G C GF G V L + S A +A+ RY C + +
Sbjct: 89 FPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSK 148
Query: 131 SAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLD-YSKGDR----NFTSFLFTMS 185
A+++VL W + P GW + E L C D Y+ G + ++T FLF
Sbjct: 149 HALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLF--- 205
Query: 186 FFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPART---------LLLG-----WGPY 231
F F +PL + SY+ + + L Q + + +++G + PY
Sbjct: 206 IFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPY 265
Query: 232 AILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNE 274
A +Y V + +L +P+ +K N I Y N+
Sbjct: 266 AAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNK 308
>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
Length = 398
Score = 53.1 bits (126), Expect = 3e-07
Identities = 54/205 (26%), Positives = 91/205 (44%), Gaps = 19/205 (9%)
Query: 13 ELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVA 72
E +V+ + +VL++ L G+ N + + +T +RTP + ++SLA+AD L LVA
Sbjct: 23 EYQVVTILLVLIICGL-GIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVAD----LMVLVA 77
Query: 73 A-TSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC----TRSQL 127
A ++ + W YG GC + ++ AS CS A RY C +
Sbjct: 78 AGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLC 137
Query: 128 AWNSAVSLVLFVW----LSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFT 183
++ A +++FVW L W L L Y + +C K RN+ S ++
Sbjct: 138 TFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISC----GYKISRNYYSPIYL 193
Query: 184 MSFFNF-AMPLFITITSYSLMEQKL 207
M F F +P+ + Y + + L
Sbjct: 194 MDFGVFYVVPMILATVLYGFIARIL 218
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 52.8 bits (125), Expect = 4e-07
Identities = 48/199 (24%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Query: 13 ELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVA 72
E+ V+ +G+V+ + L+ + N L I + K L+T + + SLA AD + L +
Sbjct: 30 EVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPF 89
Query: 73 ATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCT----RSQLA 128
+ +L + W +G+ C+ + ASI + IA RY + +S L
Sbjct: 90 GAAHILM---KMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLT 146
Query: 129 WNSAVSLVLFVWLSSAFWAALPL-LGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFF 187
N A ++L VW+ S + LP+ + W ++ C + ++ S
Sbjct: 147 KNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIV 206
Query: 188 NFAMPLFITITSYSLMEQK 206
+F +PL I + YS + Q+
Sbjct: 207 SFYVPLVIMVFVYSRVFQE 225
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 52.0 bits (123), Expect = 6e-07
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 7/152 (4%)
Query: 5 SALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSG 64
S P + +G+++ + L ++ N L I + KTP L+T +L ++SLA AD
Sbjct: 47 SESPEPLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASAD-- 104
Query: 65 ISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HH 120
+ + LV + + V RW YGS C+ + ASI + IA RY
Sbjct: 105 LVMGLLVVPFGATI-VVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSP 163
Query: 121 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLL 152
+ +S L A LV VW SA + LP+L
Sbjct: 164 FRYQSLLTRARARGLVCTVWAISALVSFLPIL 195
>gi|7669548 tachykinin receptor 3 [Homo sapiens]
Length = 465
Score = 51.6 bits (122), Expect = 8e-07
Identities = 44/190 (23%), Positives = 84/190 (44%), Gaps = 12/190 (6%)
Query: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGIS-LNALVAATS 75
LA G+V+ V L N + I+ +RT + +++LA +D+ ++ N LV
Sbjct: 90 LAYGVVVAVAVLG----NLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLV---- 141
Query: 76 SLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC--TRSQLAWNSAV 133
+ + H W +G++ C+ F ASI S AIA RY + +L+ +
Sbjct: 142 NFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATK 201
Query: 134 SLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPL 193
++ +W+ AF A P + P T C + + +G + ++ + + PL
Sbjct: 202 IVIGSIWI-LAFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHFTYHIIVIILVYCFPL 260
Query: 194 FITITSYSLM 203
I +Y+++
Sbjct: 261 LIMGITYTIV 270
>gi|22507376 G-protein coupled receptor TG1019 [Homo sapiens]
Length = 423
Score = 51.6 bits (122), Expect = 8e-07
Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 25/236 (10%)
Query: 22 VLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRVS 81
+L +E + GL N+L +F FC T + ++SL AD + N + LL
Sbjct: 98 ILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLL--- 154
Query: 82 HRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY------HHYCTRSQLAWNSAVSL 135
H W +G+ C+ + F AS+ AIA RY HH +R+ + + V
Sbjct: 155 HETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARV-- 212
Query: 136 VLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF-----LFTMSFFNFA 190
+ W + LL GH L Y G + S L+ + FF
Sbjct: 213 ------AGGLWVGILLLN-GHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPL 265
Query: 191 MPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSI 246
+ I S L + G G Q R L + Y I +L ++I + S+
Sbjct: 266 ALILFAIVSIGLTIRNRGLGG--QAGPQRAMRVLAMVVAVYTICFLPSIIFGMASM 319
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 50.4 bits (119), Expect = 2e-06
Identities = 46/157 (29%), Positives = 72/157 (45%), Gaps = 13/157 (8%)
Query: 2 AETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALA 61
A TS LP E G +L + L+ + N L I + TP L+T ++ V SLA A
Sbjct: 25 ANTSGLPGV--PWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAA 82
Query: 62 DSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHY 121
D + L +V ++L H WP G+ GC+ + ASI + A+A RY
Sbjct: 83 DLVMGL-LVVPPAATLALTGH--WPLGATGCELWTSVDVLCVTASIETLCALAVDRY--L 137
Query: 122 CTRSQLAWNSAV------SLVLFVWLSSAFWAALPLL 152
+ L + + V + V+ VW+ SA + P++
Sbjct: 138 AVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIM 174
>gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo
sapiens]
Length = 365
Score = 49.3 bits (116), Expect = 4e-06
Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 17/214 (7%)
Query: 15 EVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAAT 74
E + + M L+V LN I + T +L P + L+ SLA+ D L A++
Sbjct: 21 EKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDL---LVAVLVMP 77
Query: 75 SSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNS--- 131
S++ + RW G C+ SI IA RY + A
Sbjct: 78 LSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAK 137
Query: 132 -AVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFA 190
A ++L VW S F + PL H P + CT+ + D + T+ F
Sbjct: 138 RAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQH---DHVIYTIYSTLGAFYIP 194
Query: 191 MPLFITITSYSL------MEQKLGKSGHLQVNTT 218
+ L I I Y + + QK G S HL +T
Sbjct: 195 LTL-ILILYYRIYHAAKSLYQKRGSSRHLSNRST 227
>gi|31881792 leukotriene B4 receptor [Homo sapiens]
Length = 352
Score = 48.9 bits (115), Expect = 5e-06
Identities = 63/247 (25%), Positives = 106/247 (42%), Gaps = 23/247 (9%)
Query: 4 TSALPTGFGELEVLAVGMVLLVEALS-GLSLNTLTIFSFCKTPELRTPCHLLVLSLALAD 62
+SA P G + + ++LL AL+ GL N+ ++S K + R+ L+VL+LALAD
Sbjct: 5 SSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALAD 64
Query: 63 SGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGR----Y 118
L L+ A L ++ W +G GC+ + V+ AS+ A++ R
Sbjct: 65 ----LAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA 120
Query: 119 HHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY----SKGD 174
+ ++ A ++ +W+ S F A P+L + P T +L + S+G
Sbjct: 121 RPFVSQKLRTKAMARRVLAGIWVLS-FLLATPVL--AYRTVVPWKTNMSLCFPRYPSEGH 177
Query: 175 RNFTSFLFTMSFFNFAMPLFITITSYS-----LMEQKLGKSGHLQVNTTLPARTLLLGWG 229
R F L + F +P + SYS L ++ +S L T W
Sbjct: 178 RAF--HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWL 235
Query: 230 PYAILYL 236
PY ++ L
Sbjct: 236 PYHVVNL 242
>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
sapiens]
Length = 366
Score = 48.9 bits (115), Expect = 5e-06
Identities = 55/202 (27%), Positives = 91/202 (45%), Gaps = 18/202 (8%)
Query: 16 VLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATS 75
V A + L V ++G N LT+ + ELRT +L + S+A +D L +
Sbjct: 46 VTATCVALFVVGIAG---NLLTMLVVSRFRELRTTTNLYLSSMAFSD----LLIFLCMPL 98
Query: 76 SLLRV-SHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC---TRSQLAWNS 131
L+R+ +R W +G C+ F A++ + A++ RY C +
Sbjct: 99 DLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKG 158
Query: 132 AVSLVLFVWLSSAFWAALP---LLGWGHYD-YEPLGT--CCTLDYSKGDRNFTSFLFTMS 185
V LV+FV + AF +A P L+G H + +P T C +++ T ++ S
Sbjct: 159 RVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSS 218
Query: 186 FFNFAMPLFITITSYSLMEQKL 207
F F +P+F YSL+ +KL
Sbjct: 219 IF-FFLPVFCLTVLYSLIGRKL 239
>gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo
sapiens]
Length = 289
Score = 48.9 bits (115), Expect = 5e-06
Identities = 55/202 (27%), Positives = 91/202 (45%), Gaps = 18/202 (8%)
Query: 16 VLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATS 75
V A + L V ++G N LT+ + ELRT +L + S+A +D L +
Sbjct: 46 VTATCVALFVVGIAG---NLLTMLVVSRFRELRTTTNLYLSSMAFSD----LLIFLCMPL 98
Query: 76 SLLRV-SHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYC---TRSQLAWNS 131
L+R+ +R W +G C+ F A++ + A++ RY C +
Sbjct: 99 DLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKG 158
Query: 132 AVSLVLFVWLSSAFWAALP---LLGWGHYD-YEPLGT--CCTLDYSKGDRNFTSFLFTMS 185
V LV+FV + AF +A P L+G H + +P T C +++ T ++ S
Sbjct: 159 RVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSS 218
Query: 186 FFNFAMPLFITITSYSLMEQKL 207
F F +P+F YSL+ +KL
Sbjct: 219 IF-FFLPVFCLTVLYSLIGRKL 239
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,455,268
Number of Sequences: 37866
Number of extensions: 408754
Number of successful extensions: 1507
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 213
Number of HSP's that attempted gapping in prelim test: 1337
Number of HSP's gapped (non-prelim): 287
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.