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Search of human proteins with 21327680
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21327680 agouti signaling protein precursor [Homo sapiens]
(132 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21327680 agouti signaling protein precursor [Homo sapiens] 269 4e-73
gi|4501995 agouti related protein homolog isoform 1 [Homo sapiens] 51 3e-07
gi|6598318 agouti related protein homolog isoform 2 [Homo sapiens] 51 3e-07
gi|38490571 keratin associated protein 10-7 [Homo sapiens] 34 0.038
gi|63053515 keratin associated protein 10-3 [Homo sapiens] 33 0.085
gi|238859649 keratin associated protein 10-8 [Homo sapiens] 32 0.11
gi|38490568 keratin associated protein 10-4 [Homo sapiens] 32 0.15
gi|154759249 keratin associated protein 10-11 [Homo sapiens] 32 0.19
gi|63053512 keratin associated protein 10-1 [Homo sapiens] 31 0.25
gi|239752100 PREDICTED: hypothetical protein [Homo sapiens] 31 0.32
gi|239746604 PREDICTED: similar to Keratin-associated protein 10... 31 0.32
gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens] 31 0.32
gi|215982802 F-box only protein 5 isoform b [Homo sapiens] 30 0.55
gi|6912366 F-box only protein 5 isoform a [Homo sapiens] 30 0.55
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 30 0.55
gi|14269578 metallothionein 4 [Homo sapiens] 30 0.55
gi|145580626 E2F transcription factor 7 [Homo sapiens] 30 0.55
gi|38490587 keratin associated protein 10-12 [Homo sapiens] 30 0.55
gi|76781482 vascular endothelial growth factor A isoform c precu... 30 0.72
gi|11386183 WAS protein family, member 2 [Homo sapiens] 29 0.94
gi|14917115 keratin 31 [Homo sapiens] 29 1.2
gi|28866947 metallothionein 1F [Homo sapiens] 29 1.2
gi|123701326 zinc finger protein 831 [Homo sapiens] 29 1.2
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 28 1.6
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 28 1.6
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s... 28 1.6
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 28 1.6
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 28 1.6
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo... 28 1.6
gi|83367075 metallothionein 1E [Homo sapiens] 28 2.1
>gi|21327680 agouti signaling protein precursor [Homo sapiens]
Length = 132
Score = 269 bits (688), Expect = 4e-73
Identities = 132/132 (100%), Positives = 132/132 (100%)
Query: 1 MDVTRLLLATLLVFLCFFTANSHLPPEEKLRDDRSLRSNSSVNLLDVPSVSIVALNKKSK 60
MDVTRLLLATLLVFLCFFTANSHLPPEEKLRDDRSLRSNSSVNLLDVPSVSIVALNKKSK
Sbjct: 1 MDVTRLLLATLLVFLCFFTANSHLPPEEKLRDDRSLRSNSSVNLLDVPSVSIVALNKKSK 60
Query: 61 QIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRFFR 120
QIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRFFR
Sbjct: 61 QIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRFFR 120
Query: 121 SACSCRVLSLNC 132
SACSCRVLSLNC
Sbjct: 121 SACSCRVLSLNC 132
>gi|4501995 agouti related protein homolog isoform 1 [Homo sapiens]
Length = 132
Score = 50.8 bits (120), Expect = 3e-07
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 47 VPSVSIVALNKKSKQIGRKAAEKKRSSKKEASMKKV-VRPRTPLSAP-CVATRNSCKPPA 104
+P + + L K+ + AE+ + +A + + ++ R P S+ CV SC
Sbjct: 39 LPELPGLGLRAPLKKTTAEQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQ 98
Query: 105 PACCDPCASCQCRFFRSACSCRVL 128
CCDPCA+C CRFF + C CR L
Sbjct: 99 VPCCDPCATCYCRFFNAFCYCRKL 122
>gi|6598318 agouti related protein homolog isoform 2 [Homo sapiens]
Length = 132
Score = 50.8 bits (120), Expect = 3e-07
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 47 VPSVSIVALNKKSKQIGRKAAEKKRSSKKEASMKKV-VRPRTPLSAP-CVATRNSCKPPA 104
+P + + L K+ + AE+ + +A + + ++ R P S+ CV SC
Sbjct: 39 LPELPGLGLRAPLKKTTAEQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQ 98
Query: 105 PACCDPCASCQCRFFRSACSCRVL 128
CCDPCA+C CRFF + C CR L
Sbjct: 99 VPCCDPCATCYCRFFNAFCYCRKL 122
>gi|38490571 keratin associated protein 10-7 [Homo sapiens]
Length = 370
Score = 33.9 bits (76), Expect = 0.038
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Query: 84 RPRTPLSAPC-VATRNSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC 132
RP + +S C R +C P P+CC P +SCQ R A SC +SL C
Sbjct: 304 RPSSSVSLLCRPVCRPACCVPVPSCCAPTSSCQASCCRPA-SC--VSLLC 350
>gi|63053515 keratin associated protein 10-3 [Homo sapiens]
Length = 221
Score = 32.7 bits (73), Expect = 0.085
Identities = 20/50 (40%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 84 RPRTPLSAPC-VATRNSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC 132
RP + +S C R++C P P+CC P ++CQ R A SC +SL C
Sbjct: 153 RPSSSVSLLCRPVCRSTCCVPIPSCCAPASTCQPSCCRPA-SC--VSLLC 199
>gi|238859649 keratin associated protein 10-8 [Homo sapiens]
Length = 259
Score = 32.3 bits (72), Expect = 0.11
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 69 KKRSSKKEASMKKVVRPRTPLSAPC-VATRNSCKPPAPACCDPCASCQ 115
+K S + RP + +S C R +C P P+CC P +SCQ
Sbjct: 189 QKSSCQPACCTTSCCRPSSSVSLLCRPVCRPACCVPVPSCCVPASSCQ 236
>gi|38490568 keratin associated protein 10-4 [Homo sapiens]
Length = 401
Score = 32.0 bits (71), Expect = 0.15
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 84 RPRTPLSAPC-VATRNSCKPPAPACCDPCASCQCRFFRSACSC 125
RP + +S C R +C P P+CC P +SCQ R A SC
Sbjct: 356 RPSSSVSLLCRPVCRPACCVPVPSCCAPTSSCQPSCCRPA-SC 397
>gi|154759249 keratin associated protein 10-11 [Homo sapiens]
Length = 298
Score = 31.6 bits (70), Expect = 0.19
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Query: 84 RPRTPLSAPC-VATRNSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC 132
RP + +S C R++C P +CC P +SCQ R A SC +SL C
Sbjct: 232 RPSSSVSLLCHPVCRSTCCVPVSSCCAPTSSCQSSCCRPA-SC--VSLLC 278
>gi|63053512 keratin associated protein 10-1 [Homo sapiens]
Length = 282
Score = 31.2 bits (69), Expect = 0.25
Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 84 RPRTPLSAPC-VATRNSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC 132
RP + +S C R +C P +CC P +SCQ R A SC +SL C
Sbjct: 227 RPSSSVSLLCRPVCRPACCMPVSSCCAPASSCQASCCRPA-SC--VSLLC 273
>gi|239752100 PREDICTED: hypothetical protein [Homo sapiens]
Length = 312
Score = 30.8 bits (68), Expect = 0.32
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 84 RPRTPLSAPC-VATRNSCKPPAPACCDPCASCQ 115
RP + +S C R +C P P+CC P SCQ
Sbjct: 257 RPSSSVSLLCHPVCRPTCCMPVPSCCAPAFSCQ 289
>gi|239746604 PREDICTED: similar to Keratin-associated protein 10-8
[Homo sapiens]
Length = 312
Score = 30.8 bits (68), Expect = 0.32
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 84 RPRTPLSAPC-VATRNSCKPPAPACCDPCASCQ 115
RP + +S C R +C P P+CC P SCQ
Sbjct: 257 RPSSSVSLLCHPVCRPTCCMPVPSCCAPAFSCQ 289
>gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens]
Length = 278
Score = 30.8 bits (68), Expect = 0.32
Identities = 15/30 (50%), Positives = 19/30 (63%)
Query: 72 SSKKEASMKKVVRPRTPLSAPCVATRNSCK 101
S+ K +S++KV R P S P TRNSCK
Sbjct: 247 STHKRSSLRKVKLVRPPQSPPKNCTRNSCK 276
>gi|215982802 F-box only protein 5 isoform b [Homo sapiens]
Length = 401
Score = 30.0 bits (66), Expect = 0.55
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 67 AEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRF 118
+E ++ KK S+K +R +P C R +CK D C C C +
Sbjct: 317 SEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREG-CGFDYCTKCLCNY 367
>gi|6912366 F-box only protein 5 isoform a [Homo sapiens]
Length = 447
Score = 30.0 bits (66), Expect = 0.55
Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Query: 67 AEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRF 118
+E ++ KK S+K +R +P C R +CK D C C C +
Sbjct: 363 SEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREG-CGFDYCTKCLCNY 413
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 30.0 bits (66), Expect = 0.55
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 20 ANSHLPPEEKLRDDRSLRSNSSVNLLDVPSVSIVALNKKSKQIGRKAAEKKRSSKKEASM 79
A+S P +K R+ + +S DVP V + K K+ K E+ + KKE
Sbjct: 811 ADSEKLPIQKHRNTETSKSPEK----DVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEK 866
Query: 80 KKVVRPR 86
KK +P+
Sbjct: 867 KKSPKPK 873
>gi|14269578 metallothionein 4 [Homo sapiens]
Length = 62
Score = 30.0 bits (66), Expect = 0.55
Identities = 14/34 (41%), Positives = 15/34 (44%), Gaps = 1/34 (2%)
Query: 93 CVATRNSCKPPAPACCDPCA-SCQCRFFRSACSC 125
C R SC P P C CA C C+ CSC
Sbjct: 27 CKTCRKSCCPCCPPGCAKCARGCICKGGSDKCSC 60
>gi|145580626 E2F transcription factor 7 [Homo sapiens]
Length = 911
Score = 30.0 bits (66), Expect = 0.55
Identities = 18/66 (27%), Positives = 32/66 (48%)
Query: 31 RDDRSLRSNSSVNLLDVPSVSIVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLS 90
RDDRS + ++V L PS ++ Q + A K++S + E +V P+ P
Sbjct: 573 RDDRSSEAPATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSD 632
Query: 91 APCVAT 96
+ +A+
Sbjct: 633 STDLAS 638
>gi|38490587 keratin associated protein 10-12 [Homo sapiens]
Length = 245
Score = 30.0 bits (66), Expect = 0.55
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
Query: 84 RPRTPLSAPCVATRNSCKP----PAPACCDPCASCQ 115
RP + +S C R C+P P P+CC P +SCQ
Sbjct: 190 RPSSSVSLLC---RPVCRPARRVPVPSCCVPTSSCQ 222
>gi|76781482 vascular endothelial growth factor A isoform c
precursor [Homo sapiens]
Length = 389
Score = 29.6 bits (65), Expect = 0.72
Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 4/67 (5%)
Query: 65 KAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRFFRSACS 124
+A ++K+S + + +K R ++ PC R P C C C+ S C
Sbjct: 316 RARQEKKSVRGKGKGQKRKRKKSRPCGPCSERRKHLFVQDPQTC----KCSCKNTDSRCK 371
Query: 125 CRVLSLN 131
R L LN
Sbjct: 372 ARQLELN 378
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 29.3 bits (64), Expect = 0.94
Identities = 14/69 (20%), Positives = 30/69 (43%)
Query: 37 RSNSSVNLLDVPSVSIVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVAT 96
R +S +D V + L+ K +++ + +++ + + + R L P + T
Sbjct: 64 RVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPVLET 123
Query: 97 RNSCKPPAP 105
N+C P P
Sbjct: 124 YNTCDTPPP 132
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 28.9 bits (63), Expect = 1.2
Identities = 11/25 (44%), Positives = 12/25 (48%)
Query: 90 SAPCVATRNSCKPPAPACCDPCASC 114
S PC T KP P +PC SC
Sbjct: 369 SNPCATTNACSKPIGPCLSNPCTSC 393
>gi|28866947 metallothionein 1F [Homo sapiens]
Length = 61
Score = 28.9 bits (63), Expect = 1.2
Identities = 12/34 (35%), Positives = 15/34 (44%), Gaps = 1/34 (2%)
Query: 93 CVATRNSCKPPAPACCDPCA-SCQCRFFRSACSC 125
C + + SC P C CA C C+ CSC
Sbjct: 26 CTSCKKSCCSCCPVGCSKCAQGCVCKGASEKCSC 59
>gi|123701326 zinc finger protein 831 [Homo sapiens]
Length = 1677
Score = 28.9 bits (63), Expect = 1.2
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 43 NLLDVPSVSIVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKP 102
++L+ PS S +K Q+G ++ +S+ A P+SAP + P
Sbjct: 1003 SILEDPSCSRPQDGRKGAQLGGDKGDRMATSRPAAR-------ELPISAPGAPREATSSP 1055
Query: 103 PAPAC 107
P P C
Sbjct: 1056 PTPTC 1060
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 28.5 bits (62), Expect = 1.6
Identities = 14/55 (25%), Positives = 24/55 (43%)
Query: 56 NKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDP 110
+K++++ G KAA + + KK+ K+ + T N PP P P
Sbjct: 3851 SKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLP 3905
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 28.5 bits (62), Expect = 1.6
Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 2/60 (3%)
Query: 52 IVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPC 111
+ +KK K+ R A +KR ++ + PR A S PAP CC+ C
Sbjct: 79 VAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDTAPASF--PAPGCCENC 136
>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
sapiens]
Length = 503
Score = 28.5 bits (62), Expect = 1.6
Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 2/60 (3%)
Query: 52 IVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPC 111
+ +KK K+ R A +KR ++ + PR A S PAP CC+ C
Sbjct: 79 VAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDTAPASF--PAPGCCENC 136
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 28.5 bits (62), Expect = 1.6
Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 2/60 (3%)
Query: 52 IVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPC 111
+ +KK K+ R A +KR ++ + PR A S PAP CC+ C
Sbjct: 79 VAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDTAPASF--PAPGCCENC 136
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 28.5 bits (62), Expect = 1.6
Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 2/60 (3%)
Query: 52 IVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPC 111
+ +KK K+ R A +KR ++ + PR A S PAP CC+ C
Sbjct: 79 VAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDTAPASF--PAPGCCENC 136
>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
sapiens]
Length = 549
Score = 28.5 bits (62), Expect = 1.6
Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 2/60 (3%)
Query: 52 IVALNKKSKQIGRKAAEKKRSSKKEASMKKVVRPRTPLSAPCVATRNSCKPPAPACCDPC 111
+ +KK K+ R A +KR ++ + PR A S PAP CC+ C
Sbjct: 79 VAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDTAPASF--PAPGCCENC 136
>gi|83367075 metallothionein 1E [Homo sapiens]
Length = 61
Score = 28.1 bits (61), Expect = 2.1
Identities = 12/34 (35%), Positives = 15/34 (44%), Gaps = 1/34 (2%)
Query: 93 CVATRNSCKPPAPACCDPCA-SCQCRFFRSACSC 125
C + + SC P C CA C C+ CSC
Sbjct: 26 CTSCKKSCCSCCPVGCAKCAQGCVCKGASEKCSC 59
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,121,490
Number of Sequences: 37866
Number of extensions: 204011
Number of successful extensions: 1910
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 1812
Number of HSP's gapped (non-prelim): 155
length of query: 132
length of database: 18,247,518
effective HSP length: 91
effective length of query: 41
effective length of database: 14,801,712
effective search space: 606870192
effective search space used: 606870192
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
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Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.