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Search of human proteins with 21264575
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21264575 AT rich interactive domain 1A isoform b [Homo
sapiens]
(2068 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 4241 0.0
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 2841 0.0
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 1747 0.0
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 1741 0.0
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 1722 0.0
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 123 2e-27
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 119 3e-26
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 117 2e-25
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 112 3e-24
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 112 5e-24
gi|57864582 hornerin [Homo sapiens] 107 9e-23
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 107 2e-22
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 106 3e-22
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 106 3e-22
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 105 6e-22
gi|153792074 proline rich 12 [Homo sapiens] 105 6e-22
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 103 1e-21
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 103 2e-21
gi|55956910 meningioma 1 [Homo sapiens] 103 2e-21
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 103 2e-21
gi|150170670 piccolo isoform 2 [Homo sapiens] 102 3e-21
gi|150378539 piccolo isoform 1 [Homo sapiens] 102 3e-21
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 102 4e-21
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 102 5e-21
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 102 5e-21
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 102 5e-21
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 101 9e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni... 100 1e-20
gi|48762934 alpha 2 type I collagen [Homo sapiens] 100 1e-20
gi|55750053 atrophin-1 [Homo sapiens] 100 1e-20
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 4241 bits (11000), Expect = 0.0
Identities = 2068/2068 (100%), Positives = 2068/2068 (100%)
Query: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60
MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG
Sbjct: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60
Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120
PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP
Sbjct: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120
Query: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG
Sbjct: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG
Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
Query: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300
SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT
Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300
Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360
SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA
Sbjct: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360
Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420
PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ
Sbjct: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420
Query: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480
PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ
Sbjct: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480
Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540
QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST
Sbjct: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540
Query: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600
TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP
Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600
Query: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660
QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG
Sbjct: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660
Query: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720
VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP
Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720
Query: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780
GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ
Sbjct: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780
Query: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840
IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ
Sbjct: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840
Query: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900
MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA
Sbjct: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900
Query: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960
MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG
Sbjct: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960
Query: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020
MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER
Sbjct: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020
Query: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080
KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL
Sbjct: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080
Query: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140
NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS
Sbjct: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140
Query: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200
MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ
Sbjct: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200
Query: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260
KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY
Sbjct: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260
Query: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320
SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS
Sbjct: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320
Query: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMEN 1380
PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMEN
Sbjct: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMEN 1380
Query: 1381 RTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRR 1440
RTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRR
Sbjct: 1381 RTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRR 1440
Query: 1441 RLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLV 1500
RLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLV
Sbjct: 1441 RLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLV 1500
Query: 1501 EYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEE 1560
EYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEE
Sbjct: 1501 EYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEE 1560
Query: 1561 EEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEF 1620
EEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEF
Sbjct: 1561 EEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEF 1620
Query: 1621 DSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGP 1680
DSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGP
Sbjct: 1621 DSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGP 1680
Query: 1681 PPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILED 1740
PPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILED
Sbjct: 1681 PPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILED 1740
Query: 1741 EPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILL 1800
EPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILL
Sbjct: 1741 EPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILL 1800
Query: 1801 HHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYP 1860
HHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYP
Sbjct: 1801 HHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYP 1860
Query: 1861 ESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILA 1920
ESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILA
Sbjct: 1861 ESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILA 1920
Query: 1921 TPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLG 1980
TPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLG
Sbjct: 1921 TPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLG 1980
Query: 1981 FLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESR 2040
FLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESR
Sbjct: 1981 FLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESR 2040
Query: 2041 LLDISVSPLMNSLVSQVICDVLFLIGQS 2068
LLDISVSPLMNSLVSQVICDVLFLIGQS
Sbjct: 2041 LLDISVSPLMNSLVSQVICDVLFLIGQS 2068
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 2841 bits (7365), Expect = 0.0
Identities = 1385/1449 (95%), Positives = 1393/1449 (96%), Gaps = 21/1449 (1%)
Query: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60
MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG
Sbjct: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60
Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120
PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP
Sbjct: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120
Query: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG
Sbjct: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG
Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
Query: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300
SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT
Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300
Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360
SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA
Sbjct: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360
Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420
PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ
Sbjct: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420
Query: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480
PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ
Sbjct: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480
Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540
QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST
Sbjct: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540
Query: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600
TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP
Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600
Query: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660
QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG
Sbjct: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660
Query: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720
VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP
Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720
Query: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780
GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ
Sbjct: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780
Query: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840
IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ
Sbjct: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840
Query: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900
MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA
Sbjct: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900
Query: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960
MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG
Sbjct: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960
Query: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020
MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER
Sbjct: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020
Query: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080
KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL
Sbjct: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080
Query: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140
NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS
Sbjct: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140
Query: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200
MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ
Sbjct: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200
Query: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260
KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY
Sbjct: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260
Query: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320
SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS
Sbjct: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320
Query: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMEN 1380
PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQ RPM+
Sbjct: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQ-----NYKRPMDG 1375
Query: 1381 RTSPSKS---------PF-LHSGMKMQKAGPPV---PASH---IAPAPVQPPMIRRDITF 1424
P P+ G Q+ PP PAS P+P Q + +
Sbjct: 1376 TYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAY 1435
Query: 1425 PPGSVEATQ 1433
P + AT+
Sbjct: 1436 PATATAATE 1444
Score = 1420 bits (3676), Expect = 0.0
Identities = 753/946 (79%), Positives = 773/946 (81%), Gaps = 48/946 (5%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKP--PTPASTPHSQIPPLPGMSRSNSVGIQD 1189
PP+ G M P ST + L P P PAS + P S + +
Sbjct: 1379 PPAKRHEGEMYS--VPYSTGQGQPQQQQLPPAQPQPASQQQAAQP-------SPQQDVYN 1429
Query: 1190 AFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSG 1249
+ + +T P G Q R+S P + +M P +S
Sbjct: 1430 QYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASA 1489
Query: 1250 QGPNGGM------GDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNM-ST 1302
+ G Y+ A G+ GP H + + T+ EG+ S
Sbjct: 1490 EVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYH-GVNRTDEMLHTDQRANHEGSWPSH 1548
Query: 1303 GAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMY 1362
G QP PS P M P PP Q P PS Q +
Sbjct: 1549 GTRQPPYGPSAPVPPMTRP---PPSNYQ----------------------PPPSMQNHI- 1582
Query: 1363 QQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDI 1422
QVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDI
Sbjct: 1583 ---PQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDI 1639
Query: 1423 TFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDN 1482
TFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDN
Sbjct: 1640 TFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDN 1699
Query: 1483 SIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPM 1542
SIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPM
Sbjct: 1700 SIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPM 1759
Query: 1543 EGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQK 1602
EGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQK
Sbjct: 1760 EGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQK 1819
Query: 1603 NDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPR 1662
NDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPR
Sbjct: 1820 NDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPR 1879
Query: 1663 KHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKF 1722
KHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKF
Sbjct: 1880 KHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKF 1939
Query: 1723 PFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDF 1782
PFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDF
Sbjct: 1940 PFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDF 1999
Query: 1783 EMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLREN 1842
EMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLREN
Sbjct: 2000 EMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLREN 2059
Query: 1843 TLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVL 1902
TLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVL
Sbjct: 2060 TLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVL 2119
Query: 1903 ETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS 1962
ETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS
Sbjct: 2120 ETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS 2179
Query: 1963 LAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALL 2022
LAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALL
Sbjct: 2180 LAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALL 2239
Query: 2023 ALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS 2068
ALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS
Sbjct: 2240 ALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS 2285
Score = 86.3 bits (212), Expect = 3e-16
Identities = 141/573 (24%), Positives = 200/573 (34%), Gaps = 73/573 (12%)
Query: 228 AYALSSPRGGTPGSGAAAAAGSKP------PPSSSASASSSSSSFAQQRFGAMGGGGPSA 281
A+ RG P AAA SK PPS + S S Q +M GG
Sbjct: 1102 AFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLK 1161
Query: 282 AGGGTPQPTATPTLNQLLTSPSSAR----GYQGY--PGGDYSGGPQDG---GAGKGPADM 332
P P +TP +Q+ P +R G Q G D + ++ G P+
Sbjct: 1162 P----PTPASTPH-SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMN 1216
Query: 333 ASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS--SGGGGQPLARTPQPSSPMDQMGKM 390
S G + + MS G +GG G P +R P MG
Sbjct: 1217 TSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPR 1276
Query: 391 RPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPY----------GSQTPQRYPMTMQGRAQS 440
+ PYGG PY + + P +G+ G P G +P RYP Q + Q
Sbjct: 1277 QHYPYGG--PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334
Query: 441 AMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQP----------P 490
SY Q G S + Q T Y QQ + + Y P
Sbjct: 1335 RHD--SYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVP 1392
Query: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP-PHQQSPAPYPSQQSTTQQHPQSQP 549
T QP QQ P +QP QP QQ +QP P Q Y + T +
Sbjct: 1393 YSTGQGQPQQQQLPPAQP------QPASQQQAAQPSPQQDVYNQYGNAYPATATAATERR 1446
Query: 550 PYSQPQAQSPYQQQQPQQPA-PSTLSQQAAYPQPQS---QQSQQTAYSQQRFPPPQELSQ 605
P PQ Q P+Q + + A P T +QQ PQ Q S + A + +++
Sbjct: 1447 PAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTY 1506
Query: 606 DSFGSQAS-SAPSMTSSKG-GQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST 663
+ Q++ SAP + G + D L R + GS + G P
Sbjct: 1507 NYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANH----EGS-----WPSHGTRQP---P 1554
Query: 664 SGISSSQGEQSNPAQSPFSPHTS--PHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPG 721
G S+ + P S + P S H+P + P+P P + S+S L
Sbjct: 1555 YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQ 1614
Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQ 754
PP P S + + + P M + I G ++
Sbjct: 1615 KAGPPVPASHIAPAPVQPPMIRRDITFPPGSVE 1647
Score = 72.4 bits (176), Expect = 4e-12
Identities = 203/995 (20%), Positives = 306/995 (30%), Gaps = 175/995 (17%)
Query: 5 VAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVG 64
++PAA PP PPS + A +R G A+
Sbjct: 714 LSPAAVPG-NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS 772
Query: 65 PPQPLGKELQDGAES-------NGGGGGGGAGSGGGPGAEPD---LKNSN-GNAGPRPAL 113
P QP G ++ G S + G GG G GG +P+ L N+N +AG +
Sbjct: 773 PRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGI 832
Query: 114 NNNLTEPPGGGGGGSSDGVGAPP----------HSAAAALP--------PPAYGFGQ--- 152
N P G GG G PP H++ P PP G G
Sbjct: 833 N------PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPP 886
Query: 153 PYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNS-----HDHGF 207
P G + A A + PG + GG G P G NS + G
Sbjct: 887 PGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQG- 945
Query: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267
P + N SA +P TP + A P S + SSSS++
Sbjct: 946 PPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTN 1005
Query: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG------YQGYPGGDYSGGPQ 321
++ GG + A + + A G Y+ Y GG
Sbjct: 1006 EKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLT 1065
Query: 322 DGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ---------QRSHHAP--MSPGSSGGG 370
K ++A+ +++AA++ Q +R P + +
Sbjct: 1066 QVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKK 1125
Query: 371 GQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY 430
QP + P P+ G PQ + PP+ H SQ P
Sbjct: 1126 SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPH--------SQIP--- 1174
Query: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
P+ R+ S G Q G N +P+P Q +
Sbjct: 1175 PLPGMSRSNSV-------------GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221
Query: 491 ---SQTPHAQP--SYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545
S P+ P S ++ P S P + S Q P P+ ++ P P
Sbjct: 1222 GRMSYEPNKDPYGSMRKAPGSDP-FMSSGQGPNGGMGD--PYSRAAGP---GLGNVAMGP 1275
Query: 546 QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA--YSQQRFPPPQEL 603
+ PY PY + + + + PQP S + YS R+PP Q+
Sbjct: 1276 RQHYPYG-----GPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQ 1330
Query: 604 SQ----DSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSP 659
Q DS+G+Q S+ + + S + + Q + + + G+ EG +
Sbjct: 1331 QQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYS 1390
Query: 660 GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAV 719
++G Q +Q PAQ + P + + G+ + + PA
Sbjct: 1391 VPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGG 1450
Query: 720 PGNQMP--------PRPPSGQSDSIMHPSM------------NQSSIAQDRGYMQRNPQM 759
P NQ P PP + M P M Q ++ Q R M N
Sbjct: 1451 PQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYAN 1510
Query: 760 PQYSSPQP-GSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNAL 818
Q + P G A + +HT + + S S+G + YGP
Sbjct: 1511 RQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAP---------- 1560
Query: 819 PNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ 878
+PP PP N P+M N PQ
Sbjct: 1561 ----------------------------VPPMTRPPPS--------NYQPPPSMQNHIPQ 1584
Query: 879 VGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913
V S P NR + + +H + PP
Sbjct: 1585 VSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPP 1619
Score = 43.1 bits (100), Expect = 0.003
Identities = 74/319 (23%), Positives = 100/319 (31%), Gaps = 47/319 (14%)
Query: 11 SSLGNPPPPP-PSELKKAEQQQREE----AGGEAAAAAAAERGEMKAAAGQESEGPA--- 62
S+ G P P PS+ QQQ++ G A GEM + +G
Sbjct: 1344 STQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQ 1403
Query: 63 -VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121
+ P QP Q A+ P + D+ N GNA P A P
Sbjct: 1404 QLPPAQPQPASQQQAAQ---------------PSPQQDVYNQYGNAYPATATAATERRPA 1448
Query: 122 GGGGGG-----SSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQ 176
GG D V APP + A PP Q G A A A Q
Sbjct: 1449 GGPQNQFPFQFGRDRVSAPPGTNAQQNMPP-----QMMGGPIQASAEVAQQGTMWQGRND 1503
Query: 177 QSPGLAALQSGGGGGLEP-YAG----------PQQNSHDHGFPNH--QYNSYYPNRSAYP 223
+ A QS G P Y G Q+ +H+ +P+H + Y P+ P
Sbjct: 1504 MTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPP 1563
Query: 224 PPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283
P + P ++ + P S S S F G P A
Sbjct: 1564 MTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPAS 1623
Query: 284 GGTPQPTATPTLNQLLTSP 302
P P P + + +T P
Sbjct: 1624 HIAPAPVQPPMIRRDITFP 1642
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 1747 bits (4525), Expect = 0.0
Identities = 1079/2238 (48%), Positives = 1293/2238 (57%), Gaps = 313/2238 (13%)
Query: 25 KKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-KELQDGAESNGGG 83
++ +QQQ+++ + + A G GP + PQ G K+ G +++ G
Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117
Query: 84 GGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSA 139
+ G A P + G P L T+ P GGGGG
Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP----------- 166
Query: 140 AAALPP--PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG--GLEPY 195
AA+P YG P P A QHGGQQSPG+ + S G
Sbjct: 167 -AAVPEFNNYYGSAAPASGGPGGRAGPC----FDQHGGQQSPGMGMMHSASAAAAGAPGS 221
Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255
P QNSH+ G+PN Q N Y P Y+ GG G G
Sbjct: 222 MDPLQNSHE-GYPNSQCNHY-----------PGYSRPGAGGGGGGGGGGGGGSG------ 263
Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315
G GGGG A G G A GY G G
Sbjct: 264 ----------------GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
Query: 316 ---YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372
S Q GG GP GAA+ + AAA ++ G QR P +
Sbjct: 308 GVLSSPRQQGGGMMMGPGG-----GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNP-YSQQQGPP---SGPQQGHGYPGQPYGSQTPQ 428
L +P P + YGG+ P YS PP S PQ G G Q
Sbjct: 363 QLLTSPSPMM----------RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ--- 409
Query: 429 RYPMTMQGRAQSAMG---GLSYTQQIPPYGQQGPSGY-----GQQGQTPYYNQQSPHPQQ 480
Q A +G G Y P + + G G T +Q SP
Sbjct: 410 ------QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463
Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ-----PSQPPHQQSPAPYP 535
PH+QP QS P S PP Q+ + P + YP
Sbjct: 464 VMKRPQLYGMGSNPHSQPQ-----QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518
Query: 536 SQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQ 595
QQ Q Q Y Q Q Q PY QQPQ P L QA Y QSQQ
Sbjct: 519 QQQMPPQYGQQGVSGYCQ-QGQQPYYSQQPQPPH---LPPQAQYLPSQSQQ--------- 565
Query: 596 RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEG 655
R+ P Q++SQ+ +G++ S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE
Sbjct: 566 RYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEA 623
Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPL 714
LS VS SG +SSQG+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+
Sbjct: 624 TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPI 683
Query: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSAL 771
SPA++PG+QMPP+PP QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++
Sbjct: 684 SPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743
Query: 772 SPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAG 830
SP GGQ+H G+ S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G
Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803
Query: 831 GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGM 883
GI+ A QMHGQ P G +P GRM A M NRP+ NM++M P Q G GM
Sbjct: 804 GIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860
Query: 884 CPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMIN 942
PP +NRK QE A A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N
Sbjct: 861 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMN 920
Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSST 1002
Q PPYSM M N+SA +MM G+ KL K + K +GTP+ ESKSKKSSSST
Sbjct: 921 TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 980
Query: 1003 TTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIG 1062
TT EKITK+YELG EPERK+WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIG
Sbjct: 981 TTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIG 1040
Query: 1063 GLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAAD 1122
GL QVNKNKKWRELATNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D
Sbjct: 1041 GLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD 1100
Query: 1123 SKKSQPKIQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMS 1180
+KK QPK+QPPSPA SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G
Sbjct: 1101 TKK-QPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-G 1158
Query: 1181 RSNSVGIQDAFNDGSDST------------FQKRNSMT---------PNP---------- 1209
RS+++ + D F+D SDS+ +Q+ SM PN
Sbjct: 1159 RSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVP 1218
Query: 1210 ---------GYQPSMNTSDM-------------MGRM-------SYEPNKDPYGSMRKAP 1240
G P+ + DM MG+ SY+ +PYG ++ P
Sbjct: 1219 GSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYG--QQYP 1276
Query: 1241 GSDPFMSSGQGPNGG-------------------MGDPYSRAAGP--------------- 1266
G P SGQ P GG G P R G
Sbjct: 1277 GQGP--PSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYN 1334
Query: 1267 GLGNVAMGPRQH-----YPYGGPYDRVRTE-PGI------------GPEGNMSTGAPQPN 1308
G GP + YPY PY R R + PG GP + S+ PQ N
Sbjct: 1335 QYGGSYSGPDRRPIQGQYPY--PYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQN 1392
Query: 1309 LMPSNPD--------SGMYSPSRYPP---------QQQQQQQQRHDSYGNQFSTQGTPSG 1351
+ + D G P++ PP Q+ H+S +Q P
Sbjct: 1393 MWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYM 1452
Query: 1352 S-----------PFPSQQT--TMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQK 1398
S P PS QT ++ + SPA R +ENR SPSKSPFL S MKMQK
Sbjct: 1453 SSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS-MKMQK 1511
Query: 1399 AGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMS 1458
P VP S + P QPP IRR+ITFPPGSVEA+QPVLKQRR++T KDI TPEAWRVMMS
Sbjct: 1512 VMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMS 1571
Query: 1459 LKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYE 1518
LKSGLLAESTWALDTINILLYDD+++ TFNLSQL G LELLVEYFR+CLI+IFGIL EYE
Sbjct: 1572 LKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYE 1631
Query: 1519 VGDPGQRTLLDPGRFSKVSSPAPMEGGEEEE--ELLGPKLEEEEEEEV----VENDEE-- 1570
VGDP Q+ L S + G+EEE E + E+EE+EE E+DE+
Sbjct: 1632 VGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSS 1691
Query: 1571 IAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIG 1630
IA + D A + K SKFDKLP+KIV+KN+ FVVD SDKLGRVQEF+SGLLHW++G
Sbjct: 1692 IALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLG 1751
Query: 1631 GGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKR 1689
GGDTTEHIQTHFESK E+ P R P P A RK EG + +Q+ EK
Sbjct: 1752 GGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKGDSEEQQ--------EKS 1801
Query: 1690 ITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETP 1749
I AT+DD+LS R L ED + ESSKFPFGI A+SHRNIK+LEDEP S+DETP
Sbjct: 1802 IIATIDDVLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSHRNIKLLEDEPRSRDETP 1859
Query: 1750 LCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQ 1809
LCT+ WQDSLAKRC+CVSN +RSLSFVPGND EMSKHPGL+LILGKLILLHH+HPERK+
Sbjct: 1860 LCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKR 1919
Query: 1810 APLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLD 1869
AP TYEKEE++D+GV+C+K EWWWDCLE+LR+NTLVTLANISGQLDLS Y ESICLP+LD
Sbjct: 1920 APQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILD 1979
Query: 1870 GLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEK 1929
GLLHW VCPSAEAQDPF T+GPN+VLSPQRLVLETL KLSIQDNNVDLILATPPFSR EK
Sbjct: 1980 GLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEK 2039
Query: 1930 LYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAAT 1989
Y+T+VR++ DRKNPVCREM++ LL+NLAQGD+LAARAIAVQKGSIGNL+ FLED +
Sbjct: 2040 FYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMA 2099
Query: 1990 QFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPL 2049
Q+QQSQ +L+HMQ PP EP SVDMM RAA+ALLA+A+VDEN SEF L+E RLLDIS+S +
Sbjct: 2100 QYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAV 2159
Query: 2050 MNSLVSQVICDVLFLIGQ 2067
+NSLV+ VICDVLF IGQ
Sbjct: 2160 LNSLVASVICDVLFQIGQ 2177
Score = 53.1 bits (126), Expect = 3e-06
Identities = 224/1015 (22%), Positives = 302/1015 (29%), Gaps = 218/1015 (21%)
Query: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568
+ P+ PPHQQ A + QQ Q Q Q QQQQ Q P
Sbjct: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75
Query: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
+ S A PQP Q P + G QA SK G
Sbjct: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126
Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685
ED + P G + +G G P V+ G G A F+ +
Sbjct: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176
Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745
P GP G G SP G + + M P N
Sbjct: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227
Query: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804
GY P YS P G GG GS G GG
Sbjct: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271
Query: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864
GG A+ A +A AGG G GG G YG L
Sbjct: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310
Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918
+ P Q G GM PGG + A A A + QN+ P P +
Sbjct: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361
Query: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967
NQ MM G+ P Y +S + P P S + G A+ M
Sbjct: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Query: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018
MG +PA + + GTP + S K +LY +G P
Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
Query: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKE---------IGGLTQV 1067
+ G P GR P + + ++ + G Q
Sbjct: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQ 537
Query: 1068 NKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQ 1127
+ + + ++ + S +Q Q P D+ +SQ
Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ--------------PQQDMSQEGYGTRSQ 583
Query: 1128 PKIQP---------------PS--PAGSGSMQG-PQTPQST-------SSSMAEGGDLKP 1162
P + P PS P SGS+ P ++T S S + GD
Sbjct: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643
Query: 1163 P-----TPASTPH-SQIPPLP---------GMSRSNSVGIQDAFNDGSDSTFQKRNSMTP 1207
P +P ++PH S IP P G ++S S I A GS Q S +
Sbjct: 644 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703
Query: 1208 NPGYQPSMNTSDM------MGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD-PY 1260
+ + P+++ S M M P YG + P P S G + G+
Sbjct: 704 SSSH-PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 762
Query: 1261 SRAAGP-GLGNVAMGPRQHYPYGGPYDRV--RTEPGIGPEGNMSTGAPQPNLMPSNPDSG 1317
S ++G G GP+ +Y Y V + G GP +S PS P G
Sbjct: 763 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQP-CG 821
Query: 1318 MYSPSRYPPQQQQQQ-----QQRHDSYGNQFSTQGTPS-GSPFPS-------------QQ 1358
R P Q + S QG P G P P+ Q
Sbjct: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQA 881
Query: 1359 TTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV 1413
Q +Q S P + +SP P +S M PP +APA V
Sbjct: 882 AANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY---SMAPAMV 933
Score = 46.6 bits (109), Expect = 3e-04
Identities = 197/935 (21%), Positives = 290/935 (31%), Gaps = 165/935 (17%)
Query: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
PP+ Q + ++ H QQQ QQ QQQ Q Q Q
Sbjct: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69
Query: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567
Q Q P S S AP P QH ++ + QA P + +
Sbjct: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128
Query: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614
AP + + A Y P +QQ P + +GS A +
Sbjct: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188
Query: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666
A GGQ+ + + S ++ GS+D L EG + PG S G
Sbjct: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248
Query: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723
G G G V + A+ A + +G G+
Sbjct: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
Query: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771
PR G +M P S+++++ G QR Q P ++P L
Sbjct: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365
Query: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831
+ P M SYG +Y P P+ P + +AG A G
Sbjct: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407
Query: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
MG G M Q + SH +M GP M GS M P
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463
Query: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940
+ ++ Q + + + Q+ P YP GG G P G+ +MAGM
Sbjct: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515
Query: 941 INPQ---GPPYSMGGTMANNSAGM----AASPE----------MMGLGDVKLTPATKMNN 983
PQ P Y G G + P+ + + P M+
Sbjct: 516 QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQ 575
Query: 984 KADGT----PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMT 1039
+ GT P K + E+ + L +L G + + A G T
Sbjct: 576 EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635
Query: 1040 NLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQC 1099
+ P + S L+ + + + VG++ S + + I
Sbjct: 636 SSQGDQSNPA---QSPFSPHASPHLSSIPGGPSPSPVGS--PVGSNQSRSGPISPASIP- 689
Query: 1100 LYAFECKIERGEDPPPDIFAAADSKKSQPKI-QPPSPAGSGSMQGPQ-TPQSTSSSMAEG 1157
G PP + S P + Q P P G M G Q PQ +
Sbjct: 690 ----------GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 739
Query: 1158 GDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNT 1217
G P+ +PH P PG + S+FQ+ NS + Y P M+
Sbjct: 740 G------PSMSPH----PSPGGQMHAGI-----------SSFQQSNS---SGTYGPQMSQ 775
Query: 1218 SDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGP 1275
G S P Y + A S P G N M G S+ G LG +
Sbjct: 776 YGPQGNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 832
Query: 1276 RQHYPYGGPYDRVR-TEPGIGPEGNMSTGAPQPNL 1309
Q+ P+ G + + PG+ +G G P P +
Sbjct: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTV 867
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
sapiens]
Length = 2191
Score = 1741 bits (4508), Expect = 0.0
Identities = 1080/2247 (48%), Positives = 1297/2247 (57%), Gaps = 318/2247 (14%)
Query: 25 KKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-KELQDGAESNGGG 83
++ +QQQ+++ + + A G GP + PQ G K+ G +++ G
Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117
Query: 84 GGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSA 139
+ G A P + G P L T+ P GGGGG
Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP----------- 166
Query: 140 AAALPP--PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG--GLEPY 195
AA+P YG P P A QHGGQQSPG+ + S G
Sbjct: 167 -AAVPEFNNYYGSAAPASGGPGGRAGPC----FDQHGGQQSPGMGMMHSASAAAAGAPGS 221
Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255
P QNSH+ G+PN Q N Y P Y+ GG G G
Sbjct: 222 MDPLQNSHE-GYPNSQCNHY-----------PGYSRPGAGGGGGGGGGGGGGSG------ 263
Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315
G GGGG A G G A GY G G
Sbjct: 264 ----------------GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
Query: 316 ---YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372
S Q GG GP GAA+ + AAA ++ G QR P +
Sbjct: 308 GVLSSPRQQGGGMMMGPGG-----GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNP-YSQQQGPP---SGPQQGHGYPGQPYGSQTPQ 428
L +P P + YGG+ P YS PP S PQ G G Q
Sbjct: 363 QLLTSPSPMM----------RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ--- 409
Query: 429 RYPMTMQGRAQSAMG---GLSYTQQIPPYGQQGPSGY-----GQQGQTPYYNQQSPHPQQ 480
Q A +G G Y P + + G G T +Q SP
Sbjct: 410 ------QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463
Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ-----PSQPPHQQSPAPYP 535
PH+QP QS P S PP Q+ + P + YP
Sbjct: 464 VMKRPQLYGMGSNPHSQPQ-----QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518
Query: 536 SQQ----STTQQHPQSQPPYSQPQAQSPY--QQQQP---QQPAPSTLSQQAAYPQPQSQQ 586
QQ +T ++ PP Q S Y Q QQP QQP P L QA Y QSQQ
Sbjct: 519 QQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 578
Query: 587 SQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSI 646
R+ P Q++SQ+ +G++ S P + K ED+NL Q RPSSLPDLSGSI
Sbjct: 579 ---------RYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSI 627
Query: 647 DDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPAS 705
DDLP GTE LS VS SG +SSQG+QSNPAQSPFSPH SPHL I G PSPSPVGSP
Sbjct: 628 DDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVG 687
Query: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQY 762
QSRSGP+SPA++PG+QMPP+PP QS+S HP+++QS + Q+RG+M QRNPQM QY
Sbjct: 688 SNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY 747
Query: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNA 821
Q G ++SP GGQ+H G+ S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A
Sbjct: 748 GPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSA 807
Query: 822 NYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP---- 877
+Y G GI+ A QMHGQ P G +P GRM A M NRP+ NM++M P
Sbjct: 808 SYSGPGPGMGIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPG 864
Query: 878 ---QVGSGMCPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQG 933
Q G GM PP +NRK QE A A M AANS Q+R +P MNQ G+M + PY Q
Sbjct: 865 MSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP 924
Query: 934 INSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTES 993
+N+ + ++N Q PPYSM M N+SA +MM G+ KL K + K +GTP+ ES
Sbjct: 925 MNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPES 984
Query: 994 KSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYR 1053
KSKKSSSSTTT EKITK+YELG EPERK+WVDRYL F EE+ +++LPAVG+KPLDL+R
Sbjct: 985 KSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFR 1044
Query: 1054 LYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDP 1113
LYV VKEIGGL QVNKNKKWRELATNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+P
Sbjct: 1045 LYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEP 1104
Query: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHS 1171
PP++F+ D+KK QPK+QPPSPA SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH
Sbjct: 1105 PPEVFSTGDTKK-QPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHG 1163
Query: 1172 QIPPLPGMSRSNSVGIQDAFNDGSDST------------FQKRNSMT---------PNP- 1209
Q+ P+ G RS+++ + D F+D SDS+ +Q+ SM PN
Sbjct: 1164 QMTPMQG-GRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKD 1222
Query: 1210 ------------------GYQPSMNTSDM-------------MGRM-------SYEPNKD 1231
G P+ + DM MG+ SY+ +
Sbjct: 1223 PFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHE 1282
Query: 1232 PYGSMRKAPGSDPFMSSGQGPNGG-------------------MGDPYSRAAGP------ 1266
PYG ++ PG P SGQ P GG G P R G
Sbjct: 1283 PYG--QQYPGQGP--PSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY 1338
Query: 1267 ---------GLGNVAMGPRQH-----YPYGGPYDRVRTE-PGI------------GPEGN 1299
G GP + YPY PY R R + PG GP +
Sbjct: 1339 SSQQQEMYNQYGGSYSGPDRRPIQGQYPY--PYSRERMQGPGQIQTHGIPPQMMGGPLQS 1396
Query: 1300 MSTGAPQPNLMPSNPD--------SGMYSPSRYPP---------QQQQQQQQRHDSYGNQ 1342
S+ PQ N+ + D G P++ PP Q+ H+S
Sbjct: 1397 SSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPS 1456
Query: 1343 FSTQGTPSGS-----------PFPSQQT--TMYQQQQQVSSPAPLPRPMENRTSPSKSPF 1389
+Q P S P PS QT ++ + SPA R +ENR SPSKSPF
Sbjct: 1457 HVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPF 1516
Query: 1390 LHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGT 1449
L S MKMQK P VP S + P QPP IRR+ITFPPGSVEA+QPVLKQRR++T KDI T
Sbjct: 1517 LPS-MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVT 1575
Query: 1450 PEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIE 1509
PEAWRVMMSLKSGLLAESTWALDTINILLYDD+++ TFNLSQL G LELLVEYFR+CLI+
Sbjct: 1576 PEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLID 1635
Query: 1510 IFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEE--ELLGPKLEEEEEEEV--- 1564
IFGIL EYEVGDP Q+ L S + G+EEE E + E+EE+EE
Sbjct: 1636 IFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSE 1695
Query: 1565 -VENDEE--IAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFD 1621
E+DE+ IA + D A + K SKFDKLP+KIV+KN+ FVVD SDKLGRVQEF+
Sbjct: 1696 KTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFN 1755
Query: 1622 SGLLHWRIGGGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTPGTTDQEGP 1680
SGLLHW++GGGDTTEHIQTHFESK E+ P R P P A RK EG + +Q+
Sbjct: 1756 SGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKGDSEEQQ-- 1811
Query: 1681 PPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILED 1740
EK I AT+DD+LS R L ED + ESSKFPFGI A+SHRNIK+LED
Sbjct: 1812 ------EKSIIATIDDVLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSHRNIKLLED 1863
Query: 1741 EPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILL 1800
EP S+DETPLCT+ WQDSLAKRC+CVSN +RSLSFVPGND EMSKHPGL+LILGKLILL
Sbjct: 1864 EPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILL 1923
Query: 1801 HHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYP 1860
HH+HPERK+AP TYEKEE++D+GV+C+K EWWWDCLE+LR+NTLVTLANISGQLDLS Y
Sbjct: 1924 HHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYT 1983
Query: 1861 ESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILA 1920
ESICLP+LDGLLHW VCPSAEAQDPF T+GPN+VLSPQRLVLETL KLSIQDNNVDLILA
Sbjct: 1984 ESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILA 2043
Query: 1921 TPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLG 1980
TPPFSR EK Y+T+VR++ DRKNPVCREM++ LL+NLAQGD+LAARAIAVQKGSIGNL+
Sbjct: 2044 TPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLIS 2103
Query: 1981 FLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESR 2040
FLED + Q+QQSQ +L+HMQ PP EP SVDMM RAA+ALLA+A+VDEN SEF L+E R
Sbjct: 2104 FLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGR 2163
Query: 2041 LLDISVSPLMNSLVSQVICDVLFLIGQ 2067
LLDIS+S ++NSLV+ VICDVLF IGQ
Sbjct: 2164 LLDISISAVLNSLVASVICDVLFQIGQ 2190
Score = 59.7 bits (143), Expect = 3e-08
Identities = 215/971 (22%), Positives = 284/971 (29%), Gaps = 194/971 (19%)
Query: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568
+ P+ PPHQQ A + QQ Q Q Q QQQQ Q P
Sbjct: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75
Query: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
+ S A PQP Q P + G QA SK G
Sbjct: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126
Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685
ED + P G + +G G P V+ G G A F+ +
Sbjct: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176
Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745
P GP G G SP G + + M P N
Sbjct: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227
Query: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804
GY P YS P G GG GS G GG
Sbjct: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271
Query: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864
GG A+ A +A AGG G GG G YG L
Sbjct: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310
Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918
+ P Q G GM PGG + A A A + QN+ P P +
Sbjct: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361
Query: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967
NQ MM G+ P Y +S + P P S + G A+ M
Sbjct: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Query: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018
MG +PA + + GTP + S K +LY +G P
Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
Query: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076
+ G P GR P + + ++ G + W+E
Sbjct: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSG------DATWKET 531
Query: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136
+ S +Q Q Y+ + P P P + P +
Sbjct: 532 FWLMPPQYGQQGVSGYCQQGQQPYYS--------QQPQP------------PHLPPQAQY 571
Query: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV----GIQDAFN 1192
Q PQ S G +PP P+ + L R +S+ G D
Sbjct: 572 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLP 631
Query: 1193 DGSDSTFQKRNSMT---------PNPGYQP-----SMNTSDMMGRMSYEPNKDPYGS--M 1236
G+++T S + NP P S + S + G S P P GS
Sbjct: 632 TGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQS 691
Query: 1237 RKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVA-------MGPRQHYPYGGPYDRVR 1289
R P S + Q P G ++ P L M Q P Y +
Sbjct: 692 RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 751
Query: 1290 TEPGIGPE----GNMSTGAPQPNLMPSNPDSGMYSP--SRYPPQQQQQQQQRHDSYGNQF 1343
T P + P G M G + SN SG Y P S+Y PQ + + +
Sbjct: 752 TGPSMSPHPSPGGQMHAGI--SSFQQSN-SSGTYGPQMSQYGPQGNYSRPPAYSGVPSA- 807
Query: 1344 STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPR----PMENRTSPSKSPFL---HSGMKM 1396
S G G + Q Q PL R M+NR P + GM
Sbjct: 808 SYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ 867
Query: 1397 QKA---GPPVP 1404
Q GPP+P
Sbjct: 868 QGGPGMGPPMP 878
Score = 45.4 bits (106), Expect = 6e-04
Identities = 201/931 (21%), Positives = 296/931 (31%), Gaps = 144/931 (15%)
Query: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
PP+ Q + ++ H QQQ QQ QQQ Q Q Q
Sbjct: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69
Query: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567
Q Q P S S AP P QH ++ + QA P + +
Sbjct: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128
Query: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614
AP + + A Y P +QQ P + +GS A +
Sbjct: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188
Query: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666
A GGQ+ + + S ++ GS+D L EG + PG S G
Sbjct: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248
Query: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723
G G G V + A+ A + +G G+
Sbjct: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
Query: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771
PR G +M P S+++++ G QR Q P ++P L
Sbjct: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365
Query: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831
+ P M SYG +Y P P+ P + +AG A G
Sbjct: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407
Query: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
MG G M Q + SH +M GP M GS M P
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463
Query: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940
+ ++ Q + + + Q+ P YP GG G P G+ +MAGM
Sbjct: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515
Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSS 1000
PQ +G A E L + G S+ +
Sbjct: 516 QYPQ-----------QQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH 564
Query: 1001 STTTNEKITKLYELGGEPERKMWVDRYLAFTEEK-AMGMTNLPAVG----RKPLDLYRLY 1055
+ + + +P++ M + Y ++ A G N + +P L L
Sbjct: 565 LPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLS 624
Query: 1056 VSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPP 1115
S+ ++ T+ + + + G S+ A S + I G P P
Sbjct: 625 GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS---PHLSSIPGGPSPSP 681
Query: 1116 DIFAAADSKKSQPKIQPPSPAG-SGSMQGPQTPQSTSSSMAEGGDLKPPTP------AST 1168
+ +Q + P SPA GS PQ P S S S + + P P A T
Sbjct: 682 ---VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGT 738
Query: 1169 PH----SQIPPL---PGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221
+Q P P MS S G Q S+FQ+ NS + Y P M+
Sbjct: 739 QRNPQMAQYGPQQTGPSMSPHPSPGGQ---MHAGISSFQQSNS---SGTYGPQMSQYGPQ 792
Query: 1222 GRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGPRQHY 1279
G S P Y + A S P G N M G S+ G LG + Q+
Sbjct: 793 GNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849
Query: 1280 PYGGPYDRVR-TEPGIGPEGNMSTGAPQPNL 1309
P+ G + + PG+ +G G P P +
Sbjct: 850 PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTV 880
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 1722 bits (4461), Expect = 0.0
Identities = 1079/2291 (47%), Positives = 1293/2291 (56%), Gaps = 366/2291 (15%)
Query: 25 KKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-KELQDGAESNGGG 83
++ +QQQ+++ + + A G GP + PQ G K+ G +++ G
Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117
Query: 84 GGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSA 139
+ G A P + G P L T+ P GGGGG
Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP----------- 166
Query: 140 AAALPP--PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG--GLEPY 195
AA+P YG P P A QHGGQQSPG+ + S G
Sbjct: 167 -AAVPEFNNYYGSAAPASGGPGGRAGPC----FDQHGGQQSPGMGMMHSASAAAAGAPGS 221
Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255
P QNSH+ G+PN Q N Y P Y+ GG G G
Sbjct: 222 MDPLQNSHE-GYPNSQCNHY-----------PGYSRPGAGGGGGGGGGGGGGSG------ 263
Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315
G GGGG A G G A GY G G
Sbjct: 264 ----------------GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
Query: 316 ---YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372
S Q GG GP GAA+ + AAA ++ G QR P +
Sbjct: 308 GVLSSPRQQGGGMMMGPGG-----GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNP-YSQQQGPP---SGPQQGHGYPGQPYGSQTPQ 428
L +P P + YGG+ P YS PP S PQ G G Q
Sbjct: 363 QLLTSPSPMM----------RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ--- 409
Query: 429 RYPMTMQGRAQSAMG---GLSYTQQIPPYGQQGPSGY-----GQQGQTPYYNQQSPHPQQ 480
Q A +G G Y P + + G G T +Q SP
Sbjct: 410 ------QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463
Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ-----PSQPPHQQSPAPYP 535
PH+QP QS P S PP Q+ + P + YP
Sbjct: 464 VMKRPQLYGMGSNPHSQPQ-----QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518
Query: 536 SQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQ 595
QQ Q Q Y Q Q Q PY QQPQ P L QA Y QSQQ
Sbjct: 519 QQQMPPQYGQQGVSGYCQ-QGQQPYYSQQPQPPH---LPPQAQYLPSQSQQ--------- 565
Query: 596 RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEG 655
R+ P Q++SQ+ +G++ S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE
Sbjct: 566 RYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEA 623
Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPL 714
LS VS SG +SSQG+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+
Sbjct: 624 TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPI 683
Query: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSAL 771
SPA++PG+QMPP+PP QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++
Sbjct: 684 SPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743
Query: 772 SPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAG 830
SP GGQ+H G+ S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G
Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803
Query: 831 GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGM 883
GI+ A QMHGQ P G +P GRM A M NRP+ NM++M P Q G GM
Sbjct: 804 GIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860
Query: 884 CPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMIN 942
PP +NRK QE A A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N
Sbjct: 861 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMN 920
Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSK------ 996
Q PPYSM M N+SA +MM G+ KL K + K +GTP+ ESKSK
Sbjct: 921 TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQ 980
Query: 997 -----------------------------------------------KSSSSTTTNEKIT 1009
KSSSSTTT EKIT
Sbjct: 981 GISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKIT 1040
Query: 1010 KLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNK 1069
K+YELG EPERK+WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIGGL QVNK
Sbjct: 1041 KVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNK 1100
Query: 1070 NKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPK 1129
NKKWRELATNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D+KK QPK
Sbjct: 1101 NKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKK-QPK 1159
Query: 1130 IQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMSRSNSVGI 1187
+QPPSPA SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G RS+++ +
Sbjct: 1160 LQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISV 1218
Query: 1188 QDAFNDGSDST------------FQKRNSMT---------PNP----------------- 1209
D F+D SDS+ +Q+ SM PN
Sbjct: 1219 HDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFM 1278
Query: 1210 --GYQPSMNTSDM-------------MGRM-------SYEPNKDPYGSMRKAPGSDPFMS 1247
G P+ + DM MG+ SY+ +PYG ++ PG P
Sbjct: 1279 TQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYG--QQYPGQGP--P 1334
Query: 1248 SGQGPNGG-------------------MGDPYSRAAGP---------------GLGNVAM 1273
SGQ P GG G P R G G
Sbjct: 1335 SGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYS 1394
Query: 1274 GPRQH-----YPYGGPYDRVRTE-PGI------------GPEGNMSTGAPQPNLMPSNPD 1315
GP + YPY PY R R + PG GP + S+ PQ N+ + D
Sbjct: 1395 GPDRRPIQGQYPY--PYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARND 1452
Query: 1316 --------SGMYSPSRYPP---------QQQQQQQQRHDSYGNQFSTQGTPSGS------ 1352
G P++ PP Q+ H+S +Q P S
Sbjct: 1453 MPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQ 1512
Query: 1353 -----PFPSQQT--TMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPA 1405
P PS QT ++ + SPA R +ENR SPSKSPFL S MKMQK P VP
Sbjct: 1513 PITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS-MKMQKVMPTVPT 1571
Query: 1406 SHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLA 1465
S + P QPP IRR+ITFPPGSVEA+QPVLKQRR++T KDI TPEAWRVMMSLKSGLLA
Sbjct: 1572 SQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLA 1631
Query: 1466 ESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQR 1525
ESTWALDTINILLYDD+++ TFNLSQL G LELLVEYFR+CLI+IFGIL EYEVGDP Q+
Sbjct: 1632 ESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQK 1691
Query: 1526 TLLDPGRFSKVSSPAPMEGGEEEE--ELLGPKLEEEEEEEV----VENDEE--IAFSGKD 1577
L S + G+EEE E + E+EE+EE E+DE+ IA + D
Sbjct: 1692 ALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPD 1751
Query: 1578 KPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEH 1637
A + K SKFDKLP+KIV+KN+ FVVD SDKLGRVQEF+SGLLHW++GGGDTTEH
Sbjct: 1752 AAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEH 1811
Query: 1638 IQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDD 1696
IQTHFESK E+ P R P P A RK EG + +Q+ EK I AT+DD
Sbjct: 1812 IQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKGDSEEQQ--------EKSIIATIDD 1861
Query: 1697 MLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDW 1756
+LS R L ED + ESSKFPFGI A+SHRNIK+LEDEP S+DETPLCT+ W
Sbjct: 1862 VLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHW 1919
Query: 1757 QDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEK 1816
QDSLAKRC+CVSN +RSLSFVPGND EMSKHPGL+LILGKLILLHH+HPERK+AP TYEK
Sbjct: 1920 QDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEK 1979
Query: 1817 EEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAV 1876
EE++D+GV+C+K EWWWDCLE+LR+NTLVTLANISGQLDLS Y ESICLP+LDGLLHW V
Sbjct: 1980 EEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMV 2039
Query: 1877 CPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVR 1936
CPSAEAQDPF T+GPN+VLSPQRLVLETL KLSIQDNNVDLILATPPFSR EK Y+T+VR
Sbjct: 2040 CPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVR 2099
Query: 1937 FLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQA 1996
++ DRKNPVCREM++ LL+NLAQGD+LAARAIAVQKGSIGNL+ FLED + Q+QQSQ
Sbjct: 2100 YVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQH 2159
Query: 1997 SLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQ 2056
+L+HMQ PP EP SVDMM RAA+ALLA+A+VDEN SEF L+E RLLDIS+S ++NSLV+
Sbjct: 2160 NLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVAS 2219
Query: 2057 VICDVLFLIGQ 2067
VICDVLF IGQ
Sbjct: 2220 VICDVLFQIGQ 2230
Score = 53.1 bits (126), Expect = 3e-06
Identities = 224/1015 (22%), Positives = 302/1015 (29%), Gaps = 218/1015 (21%)
Query: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568
+ P+ PPHQQ A + QQ Q Q Q QQQQ Q P
Sbjct: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75
Query: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
+ S A PQP Q P + G QA SK G
Sbjct: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126
Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685
ED + P G + +G G P V+ G G A F+ +
Sbjct: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176
Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745
P GP G G SP G + + M P N
Sbjct: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227
Query: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804
GY P YS P G GG GS G GG
Sbjct: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271
Query: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864
GG A+ A +A AGG G GG G YG L
Sbjct: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310
Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918
+ P Q G GM PGG + A A A + QN+ P P +
Sbjct: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361
Query: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967
NQ MM G+ P Y +S + P P S + G A+ M
Sbjct: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Query: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018
MG +PA + + GTP + S K +LY +G P
Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
Query: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKE---------IGGLTQV 1067
+ G P GR P + + ++ + G Q
Sbjct: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQ 537
Query: 1068 NKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQ 1127
+ + + ++ + S +Q Q P D+ +SQ
Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ--------------PQQDMSQEGYGTRSQ 583
Query: 1128 PKIQP---------------PS--PAGSGSMQG-PQTPQST-------SSSMAEGGDLKP 1162
P + P PS P SGS+ P ++T S S + GD
Sbjct: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643
Query: 1163 P-----TPASTPH-SQIPPLP---------GMSRSNSVGIQDAFNDGSDSTFQKRNSMTP 1207
P +P ++PH S IP P G ++S S I A GS Q S +
Sbjct: 644 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703
Query: 1208 NPGYQPSMNTSDM------MGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD-PY 1260
+ + P+++ S M M P YG + P P S G + G+
Sbjct: 704 SSSH-PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 762
Query: 1261 SRAAGP-GLGNVAMGPRQHYPYGGPYDRV--RTEPGIGPEGNMSTGAPQPNLMPSNPDSG 1317
S ++G G GP+ +Y Y V + G GP +S PS P G
Sbjct: 763 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQP-CG 821
Query: 1318 MYSPSRYPPQQQQQQ-----QQRHDSYGNQFSTQGTPS-GSPFPS-------------QQ 1358
R P Q + S QG P G P P+ Q
Sbjct: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQA 881
Query: 1359 TTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV 1413
Q +Q S P + +SP P +S M PP +APA V
Sbjct: 882 AANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY---SMAPAMV 933
Score = 51.2 bits (121), Expect = 1e-05
Identities = 219/1067 (20%), Positives = 324/1067 (30%), Gaps = 191/1067 (17%)
Query: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
PP+ Q + ++ H QQQ QQ QQQ Q Q Q
Sbjct: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69
Query: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567
Q Q P S S AP P QH ++ + QA P + +
Sbjct: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128
Query: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614
AP + + A Y P +QQ P + +GS A +
Sbjct: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188
Query: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666
A GGQ+ + + S ++ GS+D L EG + PG S G
Sbjct: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248
Query: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723
G G G V + A+ A + +G G+
Sbjct: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
Query: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771
PR G +M P S+++++ G QR Q P ++P L
Sbjct: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365
Query: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831
+ P M SYG +Y P P+ P + +AG A G
Sbjct: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407
Query: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
MG G M Q + SH +M GP M GS M P
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463
Query: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940
+ ++ Q + + + Q+ P YP GG G P G+ +MAGM
Sbjct: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515
Query: 941 INPQ---GPPYSMGGTMANNSAGM----AASPE----------MMGLGDVKLTPATKMNN 983
PQ P Y G G + P+ + + P M+
Sbjct: 516 QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQ 575
Query: 984 KADGT----PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMT 1039
+ GT P K + E+ + L +L G + + A G T
Sbjct: 576 EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635
Query: 1040 NLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQC 1099
+ P + S L+ + + + VG++ S + + I
Sbjct: 636 SSQGDQSNPA---QSPFSPHASPHLSSIPGGPSPSPVGS--PVGSNQSRSGPISPASIP- 689
Query: 1100 LYAFECKIERGEDPPPDIFAAADSKKSQPKI-QPPSPAGSGSMQGPQ-TPQSTSSSMAEG 1157
G PP + S P + Q P P G M G Q PQ +
Sbjct: 690 ----------GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 739
Query: 1158 GDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNT 1217
G P+ +PH P PG + S+FQ+ NS + Y P M+
Sbjct: 740 G------PSMSPH----PSPGGQMHAGI-----------SSFQQSNS---SGTYGPQMSQ 775
Query: 1218 SDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGP 1275
G S P Y + A S P G N M G S+ G LG +
Sbjct: 776 YGPQGNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 832
Query: 1276 RQHYPYGGPYDRVR-TEPGIGPEGNMSTGAPQPN-----------LMPSNPDSGMYSPSR 1323
Q+ P+ G + + PG+ +G G P P +M + +S
Sbjct: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGS 892
Query: 1324 YPPQQQQQQQQRHDSYG---NQFSTQGTPSGSPFPSQQTTMYQQQQQV---------SSP 1371
+P Q Y N S+ P+ + V S
Sbjct: 893 FPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESK 952
Query: 1372 APLPRPMENRTSPSKSPFLHSGMKMQKAG---PPVPASHIAPAPVQP 1415
PLP + + + P S G PP P + P+P+ P
Sbjct: 953 LPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSP 999
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 123 bits (309), Expect = 2e-27
Identities = 238/953 (24%), Positives = 314/953 (32%), Gaps = 156/953 (16%)
Query: 7 PAAASSLGN-----------PPPPPPSELKKAEQQQREE---AGGEAAAAAAAERGEMKA 52
P AA + GN PP PP + + E AG + A +RGE
Sbjct: 314 PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373
Query: 53 AAGQESEGPAVGPP----QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAG 108
++GP GPP P GK A G G GA GP G AG
Sbjct: 374 QGHAGAQGPP-GPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432
Query: 109 PRPALNNNLTEP-----------PGGGGGGSSDGV-GAPPHSAAAALPPPAYGFGQPYGR 156
P N EP PG G DG G+P A LP A G P R
Sbjct: 433 -EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFR 491
Query: 157 ---SPSAVAAAAAAVFHQQHGGQQSPGLAALQSG-----GGGGLEPYAGPQQNSHDHGFP 208
P+ + + G P AA + G GG G+ G G P
Sbjct: 492 GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP 551
Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ 268
+ R PP P S PRG G G+ P + Q
Sbjct: 552 GPPGSQGESGRPG--PPGP----SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605
Query: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP--QDGGAG 326
G G GP G P PT P ++ T P +G QG PG +GGP ++G G
Sbjct: 606 GPPGKNGETGPQ----GPPGPTG-PGGDKGDTGPPGPQGLQGLPG---TGGPPGENGKPG 657
Query: 327 K-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP-------LARTP 378
+ GP A GA A A ++ +PG GG G P A P
Sbjct: 658 EPGPKGDA----GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713
Query: 379 QP----------SSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP-------QQGHGYPGQP 421
P P ++ G P P G +G P GP + G P P
Sbjct: 714 GPPGAAGTPGLQGMPGERGGLGSPGPKG-------DKGEPGGPGADGVPGKDGPRGPTGP 766
Query: 422 YGSQTPQRYPMTMQGRAQSAMGGLSYTQQIP----PYGQQGPSGY----GQQGQTPYYNQ 473
G P P + G++ + P G GP+G+ GQ G+ +
Sbjct: 767 IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGE 826
Query: 474 QSPHPQQQQ--PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531
+ ++ + PP PP + A P P Q + + P P + P
Sbjct: 827 RGAPGEKGEGGPPGVAGPPGGSGPAGP-----PGPQGVKGERGSPGGPGAAGFPGARGLP 881
Query: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591
P S + P P P + P P S A P ++ A
Sbjct: 882 GPPGSNGNPGPPGPSGSPGKDGPPGPAG-NTGAPGSPGVSGPKGDAGQP---GEKGSPGA 937
Query: 592 YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM 651
P P ++ + + P M +G + +S LSG + P
Sbjct: 938 QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSG--ERGPP 995
Query: 652 GTEGALSPGVSTSGISSSQGEQSNPAQSPF-----SP--------HTSPHLPGIRG--PS 696
G +G PG+ +G + G NP SP + SP PG G
Sbjct: 996 GPQGL--PGL--AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051
Query: 697 PSPVGSPASVAQSR--SGPLSPAAVP---GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751
P PVG PA + R SGP PA P G++ P P + D + I RG
Sbjct: 1052 PGPVG-PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRG 1110
Query: 752 YMQRNPQMP----------QYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG- 800
+ NP P SP P P PSG G + +G GP+G
Sbjct: 1111 F-PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGH-PGPIGPPGPRGN 1168
Query: 801 -GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850
G+ G +G G+P QP P A P G G G GG+ G G PY
Sbjct: 1169 RGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAG--GFAPY 1219
Score = 112 bits (280), Expect = 4e-24
Identities = 254/1070 (23%), Positives = 333/1070 (31%), Gaps = 181/1070 (16%)
Query: 7 PAAASSLGNPPPP----PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA 62
P + G+P P PP E +A G + A + G+ E
Sbjct: 185 PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL 244
Query: 63 VGPPQ---PLGKELQDGAESNGG--GGGGGAGSGGGPGAE-----PDLKNSNGNAGPRPA 112
GPP P G G + + G G G G G PG + P + G GPR A
Sbjct: 245 PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304
Query: 113 L-NNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF-GQPYGRSPSAVAAAAAAVFH 170
PG G +DG PP GF G P + A + +
Sbjct: 305 PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364
Query: 171 QQHGGQQSP-GLAALQS-GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA 228
G+ P G A Q G G+ G + G P A PP PA
Sbjct: 365 PGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP-----GLMGARGPPGPA 419
Query: 229 YALSSP--RGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGT 286
A +P RGG G A G P A A+ G G G A G
Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG-- 477
Query: 287 PQPTATPTLNQLLTSPSSARGYQGY--PGGDYSGGPQDGGAGKGPADMASQCWGAAAAAA 344
L + RG G+ P G + G AG+ A + GAA
Sbjct: 478 ------------LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525
Query: 345 AAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR-------TPQPSSPMDQMGKMR-PQPYG 396
G + +P PGS G G P ++ P PS P Q G M P P G
Sbjct: 526 RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG 585
Query: 397 --GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYP-MTMQGRAQSAMGGLSYTQQIPP 453
G + ++G P GP G PG+ G PQ P T G + G P
Sbjct: 586 NDGAPGKNGERGGPGGPGP-QGPPGK-NGETGPQGPPGPTGPGGDKGDTG---------P 634
Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ--SQPPQL 511
G QG G G P N + P + + P A ++ P + P L
Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694
Query: 512 QSSQPPYSQQPSQ----PPHQQSPAPYPSQQSTTQQH---PQSQPPYSQPQAQSPYQQQQ 564
+ P + + PP A P Q + P + + P
Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV 754
Query: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP-------PPQELSQDSFGSQAS--SA 615
P + P + P P Q + P P E + A A
Sbjct: 755 PGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGA 814
Query: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSN 675
P GG+ + + P ++G P G G P G+ +G
Sbjct: 815 PGQNGEPGGKGERGAPGEKGEGGPPGVAG-----PPGGSGPAGP-PGPQGVKGERGSPGG 868
Query: 676 PAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDS 735
P + F PG RG P P GS GP P+ PG PP P+G + +
Sbjct: 869 PGAAGF--------PGARG-LPGPPGS-----NGNPGPPGPSGSPGKDGPP-GPAGNTGA 913
Query: 736 IMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSP--RQPSGGQIHTGMGSYQQNSM 793
P ++ P+ + QPG SP + P G G+ +
Sbjct: 914 PGSPGVSG----------------PKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI-TGAR 956
Query: 794 GSYGPQG-----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQ- 840
G GP G G GPQG G +P N L P G+AG G G
Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016
Query: 841 -------------------MHGQPGIP--PYGTLPPGRMSHA-SMGNR----PYGPNMAN 874
+G PG P P PPG + A G+R P GP A
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP--AG 1074
Query: 875 MPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRP--PGYPN----MNQGGMMG--- 925
P GS P P G ET + P PG P Q G +G
Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG 1134
Query: 926 ----------TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP 965
+GPP G + G I P GP + G + S G P
Sbjct: 1135 PAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184
Score = 100 bits (250), Expect = 1e-20
Identities = 237/1032 (22%), Positives = 313/1032 (30%), Gaps = 139/1032 (13%)
Query: 17 PPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ-----PLGK 71
P PP + + Q + G+ R GQ + GPP P G
Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148
Query: 72 E----------LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121
+ ++ G G G G GP P G+ G + PP
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG-----SPGYQGPP 203
Query: 122 GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL 181
G G G PP + + P G GR + G PG
Sbjct: 204 GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGI----KGPAGIPGF 259
Query: 182 AALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTP 239
++ G + G + G P + + P + P P RG G P
Sbjct: 260 PGMKGHRG-----FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP 314
Query: 240 GS-------GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTAT 292
G+ GA + G PP +A S A+ G G G + A G +P
Sbjct: 315 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEP--G 372
Query: 293 PTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG 352
P + P G G PGG GP G P M ++ A A A GG
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGP--AGIPGAPGLMGARGPPGPAGANGAPGLRGG 430
Query: 353 AQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412
A + PG +G G+P P + G+ G + G P P
Sbjct: 431 AGE--------PGKNGAKGEP--------GPRGERGEAGIPGVPGAKGEDGKDGSPGEP- 473
Query: 413 QGHGYPGQPYGSQTPQ-RYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYY 471
+G PG P R P G G P G +G +G + P
Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNG-IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532
Query: 472 NQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531
P P S P P +P P QP P P
Sbjct: 533 PGMRGMPGSPGGPGSDGKPG--PPGSQGESGRPGPPGPSGPRGQPGVMGFPG--PKGNDG 588
Query: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591
AP + + P Q P + P Q P P P PQ Q
Sbjct: 589 APGKNGERGGPGGPGPQGPPGKNGETGP--QGPPGPTGPGGDKGDTGPPGPQGLQGLPGT 646
Query: 592 YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSL---PDLSGSIDD 648
PP + G + + + GG+ D + P L P L G
Sbjct: 647 GG----PPGENGKPGEPGPKGDA--GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP 700
Query: 649 L-PMGTEGALSP-----GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGS 702
P G +GA P T G+ GE+ PG +G P G
Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS-----------PGPKGDKGEPGGP 749
Query: 703 PASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM-QRNPQMPQ 761
A + GP P G PP P D + IA RG +R P
Sbjct: 750 GADGVPGKDGPRGPTGPIG---PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPP 806
Query: 762 YSSPQPGSALSPRQPSGGQIHTGMGSYQQNS-MGSYGPQGGQ-----YGPQG-----GYP 810
+ PG+ +P G G + G GP GG GPQG G P
Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP 866
Query: 811 RQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTL----PPGRMSHASMGNR 866
P P A G+ G P G+ G G PG P G+ PPG +
Sbjct: 867 GGPGAAGFPGAR----GLPG---PPGSNGN-PGPPG--PSGSPGKDGPPGPAGNTGAPGS 916
Query: 867 P--YGP-NMANMPPQVGS-GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMN--- 919
P GP A P + GS G PPG +A A + PPG P
Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPG----PLGIAGITGARGLAG-PPGMPGPRGSP 971
Query: 920 --QGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTP 977
QG +G P G++ G PQG P + GT G +P GL +P
Sbjct: 972 GPQGVKGESGKPGANGLSGERGPPGPQGLP-GLAGTA--GEPGRDGNPGSDGLPGRDGSP 1028
Query: 978 ATKMNNKADGTP 989
K + +G+P
Sbjct: 1029 GGKGDRGENGSP 1040
Score = 89.4 bits (220), Expect = 3e-17
Identities = 138/524 (26%), Positives = 166/524 (31%), Gaps = 75/524 (14%)
Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGE-----MKAAAGQ 56
A P PP PP + Q E GG + ++GE G+
Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757
Query: 57 ES-EGPA--VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--P 111
+ GP +GPP P G Q G G GG G GP P + G GP P
Sbjct: 758 DGPRGPTGPIGPPGPAG---QPG--DKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812
Query: 112 ALNNNLTEP--------PGGGGGGSSDGVGAPPHSAAAALPPPAYGF----GQPYGRSPS 159
EP PG G G GV PP + A PP G G P G P
Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG--PG 870
Query: 160 AVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNR 219
A A G +PG G G + GP N+ G P P
Sbjct: 871 AAGFPGARGLPGPPGSNGNPGPPG--PSGSPGKDGPPGPAGNTGAPGSPGVS----GPKG 924
Query: 220 SAYPPPAPAYALSSPRGGTPG----SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMG 275
A P + G PG +G A G PP S + G G
Sbjct: 925 DAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPG 984
Query: 276 GGGPSAAGGGTPQPTATPTLNQLLTSP--SSARGYQGYPGGDYS-GGPQDGGAGKGPADM 332
G S G P P P L P G G PG D S GG D G P
Sbjct: 985 ANGLSGE-RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP 1043
Query: 333 ASQCWGAAAAAAAAAAASGGAQQRSHHAPM-SPGSSGGGGQPLARTPQPSSPMDQMGKMR 391
+ A SG + P +PG +G G P P P G+
Sbjct: 1044 GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRG-----APGPQGPRGDKGETG 1098
Query: 392 PQPYGGT--------NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMG 443
+ G NP + P+G Q G PG P G + P S
Sbjct: 1099 ERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG-PAGPRGPV---------GPSGPP 1148
Query: 444 GLSYTQQIP-PYGQQGPSG-YGQQGQTPYYNQQSP-HPQQQQPP 484
G T P P G GP G G++G ++ SP HP Q PP
Sbjct: 1149 GKDGTSGHPGPIGPPGPRGNRGERG-----SEGSPGHPGQPGPP 1187
Score = 65.9 bits (159), Expect = 4e-10
Identities = 103/380 (27%), Positives = 123/380 (32%), Gaps = 59/380 (15%)
Query: 3 AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESE--- 59
A+ P S GNP PP PS + AG A + G K AGQ E
Sbjct: 877 ARGLPGPPGSNGNPGPPGPSG-SPGKDGPPGPAGNTGAPGSPGVSGP-KGDAGQPGEKGS 934
Query: 60 ----GPAVGPPQPLGKELQDGAESNGG-----------GGGGGAGSGGGPGAEPDLKNSN 104
GP G P PLG GA G G G G G PGA L
Sbjct: 935 PGAQGPP-GAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGAN-GLSGER 992
Query: 105 GNAGPR--PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVA 162
G GP+ P L E PG G SDG+ G P G+
Sbjct: 993 GPPGPQGLPGLAGTAGE-PGRDGNPGSDGLPGRD--------------GSPGGKGDRGEN 1037
Query: 163 AAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAY 222
+ A H G P A +SG G P AGP G +R A
Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGP-AGPAGAPGPAG-----------SRGAP 1085
Query: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAA 282
P P +G T GAA G + P + + S + Q G+ G GP
Sbjct: 1086 GPQGP----RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141
Query: 283 GGGTPQPTATPTLNQL-LTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341
G + P T P RG +G G + S G GP C G
Sbjct: 1142 VGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVG 1201
Query: 342 AAAAAAAASGGAQQRSHHAP 361
AAA A G ++ AP
Sbjct: 1202 AAAIAGI---GGEKAGGFAP 1218
Score = 58.5 bits (140), Expect = 6e-08
Identities = 128/535 (23%), Positives = 174/535 (32%), Gaps = 118/535 (22%)
Query: 515 QPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP-----PYSQPQAQSPYQQQQPQQPA 569
QPP + P++PP+ Q P Q P+ P P P Q P P
Sbjct: 90 QPPTA--PTRPPNGQGP-----------QGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG 136
Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQR---------FPPPQELSQDSFGSQASSAPSMTS 620
P + + PQ+ Q +Y + +P P S P
Sbjct: 137 PPGICESCP-TGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG 195
Query: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680
S G Q Q+ PS P G GA+ P SG + GE P +
Sbjct: 196 SPGYQGPPGEPGQAGPSG-----------PPGPPGAIGP----SGPAGKDGESGRPGRP- 239
Query: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQ----SRSGPLSPAAVPG----NQMP------- 725
P PGI+GP+ P G P R+G PG N +P
Sbjct: 240 -GERGLPGPPGIKGPAGIP-GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPG 297
Query: 726 PRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGM 785
P P G P + ++ A+ + + P P PG+A P P G + G
Sbjct: 298 PMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP-PGTAGFPGSP-GAKGEVGP 355
Query: 786 GSYQQNSMGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGINPMGAG 838
S GS G G G+ GPQG G P P N P GG MG
Sbjct: 356 AG----SPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP----------GGKGEMGPA 401
Query: 839 GQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPNMANMPPQVGSGMCPP--------PGG 889
G + G PG+ MG R P GP AN P + G P PG
Sbjct: 402 G-IPGAPGL---------------MGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP 445
Query: 890 MNRKTQETAVAMHVAANSI-QNRPPGYPNMN--------QGGMMGTGPPYGQGINSMAGM 940
+ + + A ++ PG P N +G GP GI G
Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505
Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKS 995
+G P G A G P G+ + +P ++ G P ++ +S
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560
Score = 51.6 bits (122), Expect = 8e-06
Identities = 99/381 (25%), Positives = 122/381 (32%), Gaps = 106/381 (27%)
Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--------PSP 699
++P G A+ P T+ G Q P P P PGI G + P
Sbjct: 78 EIPFGECCAVCPQPPTAPTRPPNG------QGPQGPKGDPGPPGIPGRNGDPGIPGQPGS 131
Query: 700 VGSPASVAQSRSGPLSP---------------------AAVPGNQMPPRPPSGQSDSIMH 738
GSP S P P A PG PP PP G + H
Sbjct: 132 PGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPP-GPPGTSGH 190
Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSPQ----PGSALSPRQPSGGQIHTGMGSYQQNSMG 794
P S GY Q P P + P P A+ P P+G +G + G
Sbjct: 191 PGSPGSP-----GY-QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPG-RPGERG 243
Query: 795 SYGPQG--------------------GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGI 832
GP G G+ G +G G P N LP N G G +
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN----GAPGPM 299
Query: 833 NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNR 892
P GA G+ G+PG+P + S G +P P PP G PG
Sbjct: 300 GPRGAPGE-RGRPGLPGAAGARGNDGARGSDG-QPGPPG----PP----GTAGFPGSPGA 349
Query: 893 KTQETAVAMHVAANSIQNRPPGYPNMNQG-GMMGTGPPYGQGINSMAGMINPQGPP---Y 948
K + P G P N G G P G AG P GPP
Sbjct: 350 KGEVG--------------PAGSPGSNGAPGQRGEPGPQGH-----AGAQGPPGPPGING 390
Query: 949 SMGGTMANNSAGMAASPEMMG 969
S GG AG+ +P +MG
Sbjct: 391 SPGGKGEMGPAGIPGAPGLMG 411
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 119 bits (298), Expect = 3e-26
Identities = 184/719 (25%), Positives = 250/719 (34%), Gaps = 133/719 (18%)
Query: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA------QQRFGA 273
+A P A A L +PR PGS PPP + A+ ++ A +R G
Sbjct: 13 AARTPAARAPGLLTPR--PPGSPRP------PPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 274 MGGGG--PSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDG-GAGKGPA 330
+GG SA G + T + N P+S RG + P + S GP G G
Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124
Query: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPM------ 384
+A A G A + + +S G+ P TP P+
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 385 DQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGG 444
++G RP P P P GP++ S+ P R SA GG
Sbjct: 185 TEVGLPRPAPSARPRP------PTEGPRKSVSS-----ASEHSTTEPSPAARRRPSAGGG 233
Query: 445 L---------SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSP------HPQQQQPPYSQQP 489
L S + + GPS G + +Q P P Q PP
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 490 P-----SQTPHAQPSYQQQPQSQPP--------------QLQSSQPPYSQQPSQPPHQQS 530
P S +P A PS QSQ P QL + P PS PP Q+
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 531 ----PAPYPSQQSTTQQHPQSQ-----------------PPYSQPQAQSPYQQQQPQQPA 569
PA PSQ +T+ P Q PP + P P Q P PA
Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRF-PPPQELSQDSFGSQASSAPSMTSSKGGQEDM 628
LS A P PQ+ + Q F PPP Q F AS S +++ Q
Sbjct: 414 SPPLSPLAT-PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
Query: 629 NLS---LQSRPS--SLPDLSGSIDDLPMGTEGALSP-------------GVSTSGISSSQ 670
+L+ LQ PS + P +S S P +P ++T + +
Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532
Query: 671 GEQSN-PAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPP 729
++ P Q+PFSP S LP +P P P A P SP A P Q P RPP
Sbjct: 533 SPPASFPGQAPFSPSAS--LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 590
Query: 730 SGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQ 789
+ D +S++ R + P P S P S LS +G H+ +
Sbjct: 591 TPGPD---------TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG---HSSSATST 638
Query: 790 QNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIP 848
+ Y GP+GG P +A A +P+A G P+ G PG P
Sbjct: 639 PEELRGY-----DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA----FRGAPGAP 688
Score = 83.6 bits (205), Expect = 2e-15
Identities = 193/787 (24%), Positives = 253/787 (32%), Gaps = 122/787 (15%)
Query: 5 VAPAAASSLGNPPPPPPSELKK-------AEQQQREEAGGEAAAAA--AAERGEMKAAAG 55
+ P S PPP P+ L+ + E AGG A +A R +AG
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 56 QESEGPAVGPPQ-------PLGKELQDGAESNGGGGGGGAGSG--GGPG----AEPDLKN 102
S PA PP P K G S+ G G G G G AE +
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 103 SNGNAGP-RPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAA---LPPPAYGFGQPYGRSP 158
P R AL+ G G+ A AA LP PA +P R P
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS-ARP--RPP 201
Query: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG-------GLEPYAGPQQNSHDHGFPNHQ 211
+ + + + + SP S GGG L A P + G P+ +
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG-PSAR 260
Query: 212 YNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271
P + P P AL P+ P AA A G P SSS A+ S S+ Q +
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG---PLSSSPLATPSPSAALQSQA 317
Query: 272 GAMGGGGPSAAGG----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK 327
P ++ TP P A P SPS+ Q P + Q +
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPP-------SPSAPPSLQTLPSPPATPPSQATTSLG 370
Query: 328 GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA--RTPQPSSPMD 385
P A+ + + + A A P+ S PL+ TP P +P
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430
Query: 386 QMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL 445
+ P+ PPS P Q P P S P T +A ++
Sbjct: 431 LAVHLLQAPFSP---------PPSPPVQA---PFSPPASP-PVSPSATPPSQAPPSLAAP 477
Query: 446 SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505
Q+PP P P +P PQ PP PP Q A+P P
Sbjct: 478 PL--QVPPSPPASP---------PMSPSATPPPQA--PPPLAAPPLQL--AKP-----PP 517
Query: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQP 565
PP L + PP PS P AP+ S + PP + P +P Q P
Sbjct: 518 QAPPALAT--PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575
Query: 566 QQPAPSTLSQQAAYPQPQSQQSQQ-----TAYSQQRFPPPQE-----LSQDSFGSQASSA 615
PA TL P P S A + PPP LS +SSA
Sbjct: 576 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635
Query: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLS-----------GSIDDLPM-GTEGALSPGVST 663
S G D + S PD G L G GA P
Sbjct: 636 TSTPEELRGY-DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 694
Query: 664 SGISSSQG----------EQSNPAQSPFSPHTSPHLPGIRGPSPSPVG-SPASVAQSRSG 712
+G S+ G E + PA P SP G + + + G S S Q+R G
Sbjct: 695 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 754
Query: 713 PLSPAAV 719
L A+
Sbjct: 755 ELPLGAL 761
Score = 50.8 bits (120), Expect = 1e-05
Identities = 77/314 (24%), Positives = 102/314 (32%), Gaps = 20/314 (6%)
Query: 1113 PPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ 1172
PP A A S + PSP+ + Q P T +T S + L P P + P
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346
Query: 1173 IPP-LPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQP-SMNTSDMMGRMSYEPNK 1230
PP L + + A T Q +S P+P P + ++ P +
Sbjct: 347 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406
Query: 1231 DPYGSMRKAPGSDPFMSSGQGPNG----GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYD 1286
P P S S Q PN + P+S P + P P P
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSP----PASPPVS 461
Query: 1287 RVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQ 1346
T P P S AP + PS P S SPS PP Q + Q
Sbjct: 462 PSATPPSQAPP---SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 1347 GTPSGSPFPSQ----QTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPP 1402
P+ + P Q + Q S A LP P P L + + P
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL--AAPLLQVPPS 576
Query: 1403 VPASHIAPAPVQPP 1416
PAS AP +PP
Sbjct: 577 PPASPTLQAPRRPP 590
Score = 40.0 bits (92), Expect = 0.024
Identities = 66/251 (26%), Positives = 82/251 (32%), Gaps = 29/251 (11%)
Query: 107 AGPRP--ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPP---AYGFGQPYGRSPSAV 161
+GPR AL PP + G HS++A P Y G G + S
Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658
Query: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGGGGLE--PYAGPQQNSHDHGFPNHQYNSYYPNR 219
A A H + A + G L P GP G + Y
Sbjct: 659 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP-------GSADGLCTIYETEG 711
Query: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGP 279
PAP P GT G AAA AG A +SS S Q R G + G
Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAAAGAG----------AGASSRSPKQARLGELPLGAL 761
Query: 280 SAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGA 339
A+ Q + TL LL + A G G G GG GGA +D W
Sbjct: 762 QAS---VVQHLLSRTL--LLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAE 816
Query: 340 AAAAAAAAAAS 350
+ + AS
Sbjct: 817 LLSPLDESRAS 827
Score = 38.1 bits (87), Expect = 0.090
Identities = 65/303 (21%), Positives = 103/303 (33%), Gaps = 74/303 (24%)
Query: 1133 PSPAGSGSMQGPQ-TPQSTSSSMAEG----GDLKPPTPASTPHSQIPP-LPGMSRSNSVG 1186
P P G +++ PQ TP ++ A G L P+P++ SQ PP LP S+S+
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331
Query: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246
Q A P+P PS+ T + P + P
Sbjct: 332 CQLA---------TPLPLAPPSPSAPPSLQT------------------LPSPPATPPSQ 364
Query: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGG--PYDRVRTEPGIGPEGNMSTGA 1304
++ + + +S P L +A P Q P P + P P ++T +
Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424
Query: 1305 PQ-PNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQ 1363
PQ PN + + +SP PP Q +PF
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQ-----------------------APF--------- 452
Query: 1364 QQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDIT 1423
SP P + T PS++P + +Q P + ++P+ PP +
Sbjct: 453 ------SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 1424 FPP 1426
PP
Sbjct: 507 APP 509
Score = 32.0 bits (71), Expect = 6.4
Identities = 74/353 (20%), Positives = 116/353 (32%), Gaps = 55/353 (15%)
Query: 1125 KSQPKIQPPSPAGSGSMQ-GPQTPQSTSSSMAEGGDLKPPTPASTP---HSQIPPLPGMS 1180
+S P+ P AG+ S + P S A P P S+P P P
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMT---------PNPGYQPSMNTSDMMGRMSYEPNKD 1231
+ + ++ G + KR++++ P PG S M R S +
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG-----TPSPAMARRSRAAGTE 186
Query: 1232 PYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTE 1291
G R AP + P + P G S A+ + R+ GG R +
Sbjct: 187 -VGLPRPAPSARP-----RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 1292 -------PGIGP--EGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQ 1342
P P G + G P+ PS P R PPQ ++ + G
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR-PPQVTPPRKDAAPALGPL 299
Query: 1343 FSTQ-GTPSGSPF------PSQQTTMYQQQQ--QVSSPAPLPRPMENR------------ 1381
S+ TPS S P+ T + Q+++P PL P +
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359
Query: 1382 TSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQP 1434
T PS++ +Q +P+ ++P PP + PP + P
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
Score = 31.6 bits (70), Expect = 8.4
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 15/81 (18%)
Query: 1113 PPPDIFAAADSKKSQPKIQ-PPSPAGSGSMQGPQTPQSTSSSMAEGGDL--------KPP 1163
PPP A + P +Q PPSP S ++Q P+ P + + G PP
Sbjct: 558 PPPQ----APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
Query: 1164 TPASTPHSQI--PPLPGMSRS 1182
P+ +P S + P L G S S
Sbjct: 614 PPSRSPSSTLSGPDLAGHSSS 634
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 117 bits (292), Expect = 2e-25
Identities = 176/685 (25%), Positives = 242/685 (35%), Gaps = 123/685 (17%)
Query: 225 PAPAYALSSPRGGTPGS----GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG-P 279
P P + P TP + GAA A G KP +R G +GG P
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKP---------------LAERAGGIGGATIP 71
Query: 280 SAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP-QDGGAGKGPADMASQCWG 338
+A P T+ P P+S RG + P + S GP G G
Sbjct: 72 ESAPRAGPTRTSRP--------PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123
Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPS------SPMDQMGKMRP 392
+A A G A + + +S G+ P TP P+ + ++G RP
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183
Query: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL------- 445
P P P GP++ S+ P R SA GGL
Sbjct: 184 APSARPRP------PTEGPRK-----SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232
Query: 446 --SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSP------HPQQQQPPYSQQPP-----SQ 492
S + + GPS G + +Q P P Q PP P S
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292
Query: 493 TPHAQPSYQQQPQ-SQPPQLQSSQPPYSQQPSQPPHQQSPA-PYPSQQSTTQQHPQ---- 546
+P A PS P S PP LQ+ P P+ PP Q + + P+ Q+T P
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSP----PATPPSQATTSLGSPTLQATHSFLPSPPLS 348
Query: 547 ---SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF-PPPQE 602
+ PP + P P Q P PA LS A P PQ+ + Q F PPP
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFSPPPSP 407
Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLS---LQSRPS--SLPDLSGSIDDLPMGTEGAL 657
Q F AS S +++ Q +L+ LQ PS + P +S S P
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467
Query: 658 S-------------PGVSTSGISSSQGEQSN-PAQSPFSPHTSPHLPGIRGPSPSPVGSP 703
+ P ++T + + ++ P Q+PFSP S LP +P P P
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS--LPMSPLATPPPQAPP 525
Query: 704 ASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS 763
A P SP A P Q P RPP+ D +S++ R + P P
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPD---------TSVSGPRLTLALAPGPPPPP 576
Query: 764 SPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANY 823
S P S LS +G H+ + + Y GP+GG P +A A +
Sbjct: 577 SRSPSSTLSGPDLAG---HSSSATSTPEELRGY-----DSGPEGGAAASPPPDAELAACH 628
Query: 824 PSAGMAGGINPMGAGGQMHGQPGIP 848
P+A G P+ G PG P
Sbjct: 629 PAAWSRGPAPPLA----FRGAPGAP 649
Score = 74.7 bits (182), Expect = 9e-13
Identities = 176/750 (23%), Positives = 233/750 (31%), Gaps = 170/750 (22%)
Query: 6 APAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGP 65
+P AS P P L+ + EE A A +R + A A +++ GP G
Sbjct: 107 SPGRASGTTRPGPLGQKGLRISA----EETVARGKATEAPKRSALSAGARRDTSGPTPGT 162
Query: 66 PQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGG 125
P P A G E L +A PRP TE P
Sbjct: 163 PSPAMARRSRAA-----------------GTEVGLPRPAPSARPRPP-----TEGPRKSV 200
Query: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQ 185
+S+ P AA R PSA GG Q P +L
Sbjct: 201 SSASEHSTTEPSPAAR--------------RRPSA------------GGGLQRPASRSLS 234
Query: 186 SGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAA 245
S P + P ++ P+ + P + P P AL P+ P AA
Sbjct: 235 SSA----TPLSSPARSG-----PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 285
Query: 246 AAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA 305
A G P SSS A+ S S+ P P+A P+L L + P++
Sbjct: 286 ALG---PLSSSPLATPSPSA--------------------PPSPSAPPSLQTLPSPPATP 322
Query: 306 RGYQGYPGGDYSGGPQDGGAGKG-PADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP 364
P G P A+ + + + A A P+
Sbjct: 323 --------------PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 368
Query: 365 GSSGGGGQPLA--RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPY 422
S PL+ TP P +P + P+ PPS P Q P P
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP---------PPSPPVQA---PFSPP 416
Query: 423 GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQ 482
S P T +A ++ Q+PP P P +P PQ
Sbjct: 417 ASP-PVSPSATPPSQAPPSLAAPPL--QVPPSPPASP---------PMSPSATPPPQA-- 462
Query: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
PP PP Q A+P P PP L + PP PS P AP+ S
Sbjct: 463 PPPLAAPPLQL--AKP-----PPQAPPALAT--PPLQALPSPPASFPGQAPFSPSASLPM 513
Query: 543 QHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQ-----TAYSQQRF 597
+ PP + P +P Q P PA TL P P S A +
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573
Query: 598 PPPQE-----LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLS--------- 643
PPP LS +SSA S G D + S PD
Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-DSGPEGGAAASPPPDAELAACHPAAW 632
Query: 644 --GSIDDLPM-GTEGALSPGVSTSGISSSQG----------EQSNPAQSPFSPHTSPHLP 690
G L G GA P +G S+ G E + PA P SP
Sbjct: 633 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 692
Query: 691 GIRGPSPSPVG-SPASVAQSRSGPLSPAAV 719
G + + + G S S Q+R G L A+
Sbjct: 693 GGKAAAGAGAGASSRSPKQARLGELPLGAL 722
Score = 47.0 bits (110), Expect = 2e-04
Identities = 75/311 (24%), Positives = 102/311 (32%), Gaps = 30/311 (9%)
Query: 1121 ADSKKSQPK------IQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIP 1174
A + SQPK ++PP P +SS +A PP+P++ P Q
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Query: 1175 PLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQP-SMNTSDMMGRMSYEPNKDPY 1233
P P + + A T Q +S P+P P + ++ P + P
Sbjct: 316 PSPPATPPS-----QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370
Query: 1234 GSMRKAPGSDPFMSSGQGPNG----GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR 1289
P S S Q PN + P+S P + P P P
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSP----PASPPVSPSA 425
Query: 1290 TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP 1349
T P P S AP + PS P S SPS PP Q + Q P
Sbjct: 426 TPPSQAPP---SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482
Query: 1350 SGSPFPSQ----QTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPA 1405
+ + P Q + Q S A LP P P L + + P PA
Sbjct: 483 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL--AAPLLQVPPSPPA 540
Query: 1406 SHIAPAPVQPP 1416
S AP +PP
Sbjct: 541 SPTLQAPRRPP 551
Score = 45.4 bits (106), Expect = 6e-04
Identities = 67/309 (21%), Positives = 107/309 (34%), Gaps = 25/309 (8%)
Query: 1121 ADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSM--AEGGDLKPPTPASTPHSQIP-PLP 1177
A S + +P + P + S + + T S ++ + GG L+ P S S P P
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 1178 GMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMR 1237
S ++ G A S + ++ P P + + +G +S P P S
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303
Query: 1238 KAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPE 1297
+P + P + + P P S+A LG+ + + P + T P P+
Sbjct: 304 PSPSAPPSLQTLPSPPA---TPPSQAT-TSLGSPTLQATHSFLPSPPLSPLATPP---PQ 356
Query: 1298 GNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQ 1357
+ P PS P S SP P Q H Q S P P
Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH-------LLQAPFSPPPSPPV 409
Query: 1358 QTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPM 1417
Q SP P + T PS++P + +Q P + ++P+ PP
Sbjct: 410 QAPF--------SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461
Query: 1418 IRRDITFPP 1426
+ PP
Sbjct: 462 APPPLAAPP 470
Score = 40.0 bits (92), Expect = 0.024
Identities = 66/251 (26%), Positives = 82/251 (32%), Gaps = 29/251 (11%)
Query: 107 AGPRP--ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPP---AYGFGQPYGRSPSAV 161
+GPR AL PP + G HS++A P Y G G + S
Sbjct: 560 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619
Query: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGGGGLE--PYAGPQQNSHDHGFPNHQYNSYYPNR 219
A A H + A + G L P GP G + Y
Sbjct: 620 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP-------GSADGLCTIYETEG 672
Query: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGP 279
PAP P GT G AAA AG A +SS S Q R G + G
Sbjct: 673 PESATPAPGALDPGPSPGTSGGKAAAGAG----------AGASSRSPKQARLGELPLGAL 722
Query: 280 SAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGA 339
A+ Q + TL LL + A G G G GG GGA +D W
Sbjct: 723 QAS---VVQHLLSRTL--LLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAE 777
Query: 340 AAAAAAAAAAS 350
+ + AS
Sbjct: 778 LLSPLDESRAS 788
Score = 34.7 bits (78), Expect = 0.99
Identities = 67/324 (20%), Positives = 105/324 (32%), Gaps = 42/324 (12%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTP---HSQIPPLPGMSRSNSVGIQ 1188
P S +G + + P S A P P S+P P P + + +
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 1189 DAFNDGSDSTFQKRNSMT---------PNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKA 1239
+ G + KR++++ P PG S M R S + G R A
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPG-----TPSPAMARRSRAAGTE-VGLPRPA 184
Query: 1240 PGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTE-------P 1292
P + P + P G S A+ + R+ GG R + P
Sbjct: 185 PSARP-----RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239
Query: 1293 GIGP--EGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS 1350
P G + G P+ PS P R PPQ ++ + G S+ P
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALR-PPQVTPPRKDAAPALGPLSSS---PL 295
Query: 1351 GSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAP 1410
+P PS + + P+P P T+ SP L + +P+ ++P
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF------LPSPPLSP 349
Query: 1411 APVQPPMIRRDITFPPGSVEATQP 1434
PP + PP + P
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPP 373
Score = 34.7 bits (78), Expect = 0.99
Identities = 59/280 (21%), Positives = 89/280 (31%), Gaps = 64/280 (22%)
Query: 650 PMGTEGALSPG-VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIR----GPSPSPVGSPA 704
P G PG + G+ S E ++ +P S G R GP+P SPA
Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG-TPSPA 166
Query: 705 SVAQSRS-GPLSPAAVPGNQMPPRPPS-GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762
+SR+ G P PRPP+ G S+ S ++
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------------------EH 206
Query: 763 SSPQPGSALSPRQPSGGQIHT------GMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYN 816
S+ +P A R +GG + + +S GP +P QP
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266
Query: 817 AL-----PNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPG--------------- 856
L P P A + P+ + P PP + PP
Sbjct: 267 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326
Query: 857 ---------RMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
+ +H+ + + P P +A PPQ + PP
Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSP-LATPPPQAPPALALPP 365
Score = 31.6 bits (70), Expect = 8.4
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 15/81 (18%)
Query: 1113 PPPDIFAAADSKKSQPKIQ-PPSPAGSGSMQGPQTPQSTSSSMAEGGDL--------KPP 1163
PPP A + P +Q PPSP S ++Q P+ P + + G PP
Sbjct: 519 PPPQ----APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574
Query: 1164 TPASTPHSQI--PPLPGMSRS 1182
P+ +P S + P L G S S
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSS 595
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 112 bits (281), Expect = 3e-24
Identities = 255/1061 (24%), Positives = 329/1061 (31%), Gaps = 202/1061 (19%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAV--- 63
P S P PP + + Q E G A+ RG +G A
Sbjct: 180 PMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPG 239
Query: 64 -----GPPQPLGKELQDGAESNGG--------------GGGGGAGSGGGPGAEPDLKNSN 104
GPP P G G G G G AG G PG+ P +
Sbjct: 240 RPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS-PGENGAP 298
Query: 105 GNAGPRPALNNNLTEP--PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVA 162
G GPR L P PG G +DG + AA PP G P G P AV
Sbjct: 299 GQMGPR-GLPGERGRPGAPGPAGARGNDG------ATGAAGPPGPTGPAGPPG-FPGAVG 350
Query: 163 AAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAY 222
A A G + G+ G G AGP N G P + + P +
Sbjct: 351 AKGEAGPQGPRGSEGPQGVRG--EPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408
Query: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAA 282
P A S P+G PG G G+ P + S + + G G GP+
Sbjct: 409 PGFPGARGPSGPQG--PG-GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465
Query: 283 GG-----GTPQPTATPTLNQLLTSPSSARG---YQGYPGGDYSGGPQDGGAGKGPADMAS 334
G G P PT P P RG +G+PG D GP+ +G A
Sbjct: 466 EGKRGARGEPGPTGLP-------GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518
Query: 335 QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQP 394
A A GA+ + +P SPG G G P P Q G+ P
Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTG-SPGSPGPDGKTGPP--------GPAGQDGRPGPPG 569
Query: 395 YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPY 454
G + G P GP+ G PG+ P A+G +
Sbjct: 570 PPGARGQAGVMGFP-GPKGAAGEPGKAGERGVPG---------PPGAVGPAGKDGEAGAQ 619
Query: 455 GQQGPSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513
G GP+G G++G+ Q P P +Q P P ++
Sbjct: 620 GPPGPAGPAGERGE------------------------QGPAGSPGFQGLPGPAGPPGEA 655
Query: 514 SQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ--------QP 565
+P P AP PS + P + P P +
Sbjct: 656 GKPGEQGVPGD-----LGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710
Query: 566 QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKG-- 623
AP Q A P Q ++ A P P+ D+ A +P +G
Sbjct: 711 DAGAPGAPGSQGA-PGLQGMPGERGAAG---LPGPKGDRGDAGPKGADGSPGKDGVRGLT 766
Query: 624 ----------GQEDMNLSLQSRPSSLPDLSGSIDDL----PMGTEGALSPGVSTSGISSS 669
D S S P+ G+ D P G G P G
Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP----PGADGQ 822
Query: 670 QGEQSNPAQSPFSPHTSPHLPGIRGPSPSP-----VGSP-ASVAQSRSGPLSPAAVPG-- 721
G + P + P PG GP+ P VG+P A A+ +GP PG
Sbjct: 823 PGAKGEPGDAGAKGDAGP--PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880
Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI 781
++ P PSG + P ++ G R P + +PG P P
Sbjct: 881 GRVGPPGPSGNAG----PPGPPGPAGKEGGKGPRGETGP---AGRPGEVGPPGPPGPAG- 932
Query: 782 HTGMGSYQQNSMGSYGPQG--GQYGPQG--------GYPRQPNYNALPNANYPSAGMAGG 831
++ S G+ GP G G GPQG G P Q P PS G G
Sbjct: 933 -------EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS-GEPGK 984
Query: 832 INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGS---------- 881
P GA G+ G PG P G PPG R P P + GS
Sbjct: 985 QGPSGASGE-RGPPG--PMG--PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039
Query: 882 GMCPPPG--------------GMNRKTQETAVAMHVA-ANSIQNRPPGYPNMNQGGMMGT 926
G PPG G + ET A + R P P +G T
Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET 1099
Query: 927 GPPYGQGINSMAGMINPQGPPYSMG--GTMANNSAGMAASP 965
G +GI G QGPP G G + A A P
Sbjct: 1100 GEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGP 1140
Score = 102 bits (254), Expect = 4e-21
Identities = 239/1046 (22%), Positives = 326/1046 (31%), Gaps = 234/1046 (22%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66
P G P PP P L GG A + E K+ G GP +GP
Sbjct: 138 PGLPGPPGPPGPPGPPGL-----------GGNFAPQLSYGYDE-KSTGGISVPGP-MGPS 184
Query: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGG 126
P G G G G GP EP ++G GPR PPG G
Sbjct: 185 GPRGLP--------GPPGAPGPQGFQGPPGEPGEPGASGPMGPRG--------PPGPPGK 228
Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
DG P G+P R P G + PG A L
Sbjct: 229 NGDDGEAGKP--------------GRPGERGPPG-----------PQGARGLPGTAGLP- 262
Query: 187 GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG-SGAAA 245
G G ++G D G PA P G+PG +GA
Sbjct: 263 -GMKGHRGFSGLDGAKGDAG--------------------PAGPKGEP--GSPGENGAPG 299
Query: 246 AAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA 305
G + P + + A+ GA G GP P PT P+
Sbjct: 300 QMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP-------PGPTG----------PAGP 342
Query: 306 RGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA--QQRSHHAPMS 363
G+ G G GPQ +GP + + A AA A + GA Q + A +
Sbjct: 343 PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402
Query: 364 PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG 423
PG +G G P AR PS P Q G P GP+ G PG P
Sbjct: 403 PGIAGAPGFPGAR--GPSGP-------------------QGPGGPPGPKGNSGEPGAP-- 439
Query: 424 SQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSP-----H 477
+ G + P G QGP G G++G+ + P
Sbjct: 440 ----------------GSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483
Query: 478 PQQQQPPYSQQPPSQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPS 536
P ++ P S+ P A P + P P P + +P + A P
Sbjct: 484 PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE-------AGLPG 536
Query: 537 QQSTTQQHPQSQPPYSQPQAQSPY-QQQQPQQPAPSTLSQQA---AYPQPQSQQSQQTAY 592
+ T P S P + P Q +P P P QA +P P+ +
Sbjct: 537 AKGLTGS-PGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595
Query: 593 SQQRFPPPQEL-----SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID 647
++ P P G+Q P+ + + G++ S + LP +G
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ--GLPGPAGPPG 653
Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVG-SPASV 706
+ E + + G S ++GE+ P + G++GP P P G A+
Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGERGFPGER-----------GVQGP-PGPAGPRGANG 701
Query: 707 AQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQ 766
A G A PG P Q M + + +G R P+ +
Sbjct: 702 APGNDGAKGDAGAPGAPGSQGAPGLQG---MPGERGAAGLPGPKG--DRGDAGPKGADGS 756
Query: 767 PG--------SALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--------GQYGPQG--G 808
PG + P P+G G + G GP G G+ GP G G
Sbjct: 757 PGKDGVRGLTGPIGPPGPAGAPGDKG----ESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812
Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTL--PPGRMSHASMG 864
+ P + P A AG G P G G G PG P G + P + + S G
Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA-GPPG--PIGNVGAPGAKGARGSAG 869
Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM 924
P P G P P G N+ PPG P +GG
Sbjct: 870 ----PPGATGFPGAAGRVGPPGPSG----------------NAGPPGPPG-PAGKEGGKG 908
Query: 925 GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG---DVKLTPATKM 981
G G G P GP G A+ AG +P G+ V P +
Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968
Query: 982 NNKADGTPKTESKSKKSSSSTTTNEK 1007
G P + K S + E+
Sbjct: 969 ERGFPGLPGPSGEPGKQGPSGASGER 994
Score = 99.8 bits (247), Expect = 3e-20
Identities = 230/982 (23%), Positives = 297/982 (30%), Gaps = 172/982 (17%)
Query: 31 QREEAGGEAAAAAAAERGEMKAAAGQESEGPA--------------VGPPQPLGKELQDG 76
+R G A A G AA GPA GP P G E G
Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368
Query: 77 AESNGG--GGGGGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV 132
G G G AG G PGA+ P K +NG G A PG G G
Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF-----PGARGPSGPQGP 423
Query: 133 GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192
G PP + P G P + + V G Q PG A + G
Sbjct: 424 GGPPGPKGNSGEP-----GAPGSKGDTGAKGEPGPV-----GVQGPPGPAGEEGKRGARG 473
Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP 252
EP GP G P P +P A ++ P+G G+ AG K
Sbjct: 474 EP--GPT------GLPGPPGERGGPGSRGFPG---ADGVAGPKGPAGERGSPGPAGPKGS 522
Query: 253 PSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYP 312
P + + A+ G+ G GP G P A P ARG G
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG--PPGPAGQDGRPGPPGPPGARGQAGV- 579
Query: 313 GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP----GSSG 368
G P GA P + A A G A + P P G G
Sbjct: 580 ----MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635
Query: 369 GGGQP-LARTPQPSSPMDQMGKMR----PQPYGGTNPYSQQ-----------QGPP--SG 410
G P P P+ P + GK P G P + QGPP +G
Sbjct: 636 PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695
Query: 411 PQQGHGYPGQP--YGSQTPQRYPMTMQGRAQSAMGGLSYTQQIP-PYGQQGPSGYGQQGQ 467
P+ +G PG G P + M G +P P G +G +G
Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755
Query: 468 TPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP---QSQPPQLQSSQPPYSQQPSQ 524
+P + PP P + PS P + P PP +
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815
Query: 525 PPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584
PP + + PP P P P + + A + +
Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPP-------GPAGPAGPPGPIGNVGAPGAKGARGSA 868
Query: 585 QQSQQTAY--SQQRFPPPQELSQDS-------FGSQASSAPSMTSSKGGQEDMNLSLQSR 635
T + + R PP G + P + G+ +
Sbjct: 869 GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPG-EVGPPGP 927
Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGP 695
P + D P G G P GI+ +G P Q PG+ GP
Sbjct: 928 PGPAGEKGSPGADGPAGAPGTPGP----QGIAGQRGVVGLPGQ-----RGERGFPGLPGP 978
Query: 696 SPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS--GQSDSIMHPSMNQSSIAQ-DRGY 752
S P S A GP P PG PP G + P + S A+ DRG
Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG- 1037
Query: 753 MQRNPQMPQYSSPQPGSA--LSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGG 808
+ P P + PG+ + P SG + TG G GP G G GPQG
Sbjct: 1038 -ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAG----PAGPVGPVGARGPAGPQG- 1091
Query: 809 YPRQPNYNALPNANYPSAGMAG--GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866
P + G G GI + G PG PPG S G +
Sbjct: 1092 ----------PRGDKGETGEQGDRGIKGHRGFSGLQGPPG-------PPG-----SPGEQ 1129
Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926
GP+ A+ P +G PPG PG +N G+ G
Sbjct: 1130 --GPSGASGP----AGPRGPPGSAGA--------------------PGKDGLN--GLPGP 1161
Query: 927 -GPPYGQGINSMAGMINPQGPP 947
GPP +G AG + P GPP
Sbjct: 1162 IGPPGPRGRTGDAGPVGPPGPP 1183
Score = 98.6 bits (244), Expect = 6e-20
Identities = 196/822 (23%), Positives = 257/822 (31%), Gaps = 146/822 (17%)
Query: 17 PPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDG 76
PP P E + ++ R E G ERG + ++G A GP P G+ G
Sbjct: 459 PPGPAGE--EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA-GPKGPAGERGSPG 515
Query: 77 AESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134
G G G G G PGA+ L S G+ GP + T PPG G G
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAK-GLTGSPGSPGP-----DGKTGPPGPAGQDGRPGPPG 569
Query: 135 PPHSAAAA----LPPPAYGFGQPYGRS-----PSAVAAAAAAVFHQQHGGQQSPGLAALQ 185
PP + A P P G+P G++ P A A + G Q PG A
Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEP-GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628
Query: 186 S-------GGGGGLEPYAGPQQNSHDHGFPNHQ----------------YNSYYPNRSAY 222
G G + GP + G P Q + R
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688
Query: 223 PPPAPAYALSSPRG--GTPGS-------GAAAAAGSKPPPSSSASASSSSSSFAQQRFGA 273
PP PA PRG G PG+ GA A GS+ P ++ G
Sbjct: 689 GPPGPA----GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744
Query: 274 MGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDG----GAGKGP 329
G GP A G + LT P G G PG GP GA P
Sbjct: 745 RGDAGPKGADGSPGKDGVRG-----LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP 799
Query: 330 ADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQ-PSSPMDQMG 388
D G A A Q + P G+ G G P P P P+ +G
Sbjct: 800 GDRGEP--GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVG 857
Query: 389 KMRPQ-------PYGGTN-PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA-- 438
+ P G T P + + P GP G PG P P +G
Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG--------PAGKEGGKGP 909
Query: 439 QSAMGGLSYTQQIPPYGQQGPSGY----------------------GQQGQTPYYNQQSP 476
+ G ++ P G GP+G GQ+G Q+
Sbjct: 910 RGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGE 969
Query: 477 HPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP--Y 534
P S +P Q P + P P + P S + P + SP
Sbjct: 970 RGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGS 1029
Query: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594
P + + + PP P A P P P P +S +T +
Sbjct: 1030 PGAKGDRGETGPAGPP-GAPGA--------PGAPGP-------VGPAGKSGDRGETGPAG 1073
Query: 595 QRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654
P ++ G Q G Q D + S L G P G+
Sbjct: 1074 PAGPVGPVGARGPAGPQGPRGDK--GETGEQGDRGIKGHRGFSGLQGPPG-----PPGSP 1126
Query: 655 GALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSR-SGP 713
G P SG S G + P + +P G+ G P P+G P ++ +GP
Sbjct: 1127 GEQGP----SGASGPAGPRGPPGSAG-----APGKDGLNG-LPGPIGPPGPRGRTGDAGP 1176
Query: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQR 755
+ P PG PP PPS D P Q A D G R
Sbjct: 1177 VGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEK-AHDGGRYYR 1217
Score = 82.8 bits (203), Expect = 3e-15
Identities = 127/505 (25%), Positives = 158/505 (31%), Gaps = 90/505 (17%)
Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGK-ELQ 74
PP P + K E AG A A +RGE GP QP K E
Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830
Query: 75 DGAESNGGGGGGGAGSGGGPG-----AEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129
D G G AG G PG P K + G+AGP P G G++
Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP----------PGATGFPGAA 880
Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
VG P S A P P G+ G+ P G+ P +G
Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKGPR---------------GETGP------AGRP 919
Query: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAA 247
G + P GP + + G P + P P P ++ RG G PG
Sbjct: 920 GEVGP-PGPPGPAGEKGSPGADGPAGAPG-----TPGP-QGIAGQRGVVGLPGQRGERGF 972
Query: 248 GSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSA 305
P PS G G GPS A G G P P P L P
Sbjct: 973 PGLPGPS-----------------GEPGKQGPSGASGERGPPGPMGPPG----LAGPPGE 1011
Query: 306 RGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAA----AASGGAQQRSHHAP 361
G +G PG + S G KG A A A +G + R P
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGP 1071
Query: 362 MSPGSSGG--GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP-QQGHGYP 418
P G G + A P + G+ + G +S QGPP P G P
Sbjct: 1072 AGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGP 1131
Query: 419 GQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSPH 477
G P+ P + + + GL P G GP G G G P
Sbjct: 1132 SGASGPAGPRGPPGSAGAPGKDGLNGLP-----GPIGPPGPRGRTGDAGPVGPPGPPGP- 1185
Query: 478 PQQQQPP-------YSQQPPSQTPH 495
P PP + QPP + H
Sbjct: 1186 PGPPGPPSAGFDFSFLPQPPQEKAH 1210
Score = 62.0 bits (149), Expect = 6e-09
Identities = 113/447 (25%), Positives = 146/447 (32%), Gaps = 111/447 (24%)
Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGP 61
A +V P S PP PP K+ + R E G AG+ E
Sbjct: 880 AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG----------------PAGRPGEVG 923
Query: 62 AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121
GPP P G++ GA+ G AG+ G PG + G AG R + P
Sbjct: 924 PPGPPGPAGEKGSPGAD-------GPAGAPGTPGPQ-------GIAGQR-----GVVGLP 964
Query: 122 GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL 181
G G G LP P+ G+P + PS + G++ P
Sbjct: 965 GQRGERGFPG-----------LPGPS---GEPGKQGPSGAS------------GERGP-- 996
Query: 182 AALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGS 241
G G AGP S G P + + P R P + P G
Sbjct: 997 -----PGPMGPPGLAGPPGESGREGAPGAEGS---PGRDGSPGAKGDRGETGPAGPPGAP 1048
Query: 242 GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTS 301
GA A G P S + + G +G GP AG P+ T Q
Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP--AGPQGPRGDKGETGEQ---G 1103
Query: 302 PSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAP 361
+G++G+ G GP +GP + ASG A R
Sbjct: 1104 DRGIKGHRGFSGLQGPPGPPGSPGEQGP-----------------SGASGPAGPRG---- 1142
Query: 362 MSPGSSGGGGQP-LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420
PGS+G G+ L P P P P P G T + GPP GP G PG
Sbjct: 1143 -PPGSAGAPGKDGLNGLPGPIGP--------PGPRGRTGD-AGPVGPP-GPPGPPGPPGP 1191
Query: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSY 447
P P Q +A GG Y
Sbjct: 1192 PSAGFDFSFLPQPPQEKAHD--GGRYY 1216
Score = 36.6 bits (83), Expect = 0.26
Identities = 54/222 (24%), Positives = 70/222 (31%), Gaps = 25/222 (11%)
Query: 1108 ERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAS 1167
ERG PP A PP PAG +G Q P + G PP A
Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656
Query: 1168 TPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYE 1227
P Q P +G + F + PG + G +
Sbjct: 657 KPGEQGVP-------GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK 709
Query: 1228 PNKDPYGS--MRKAPG-----SDPFMSSGQGPNGGMGD--PYSRAAGPGLGNV-----AM 1273
+ G+ + APG + + GP G GD P PG V +
Sbjct: 710 GDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI 769
Query: 1274 GPRQHYPYGGPYDRVRTEPGIGPEG-NMSTGAPQPNLMPSNP 1314
GP P G P D+ + P GP G + GAP P P
Sbjct: 770 GPPG--PAGAPGDKGESGPS-GPAGPTGARGAPGDRGEPGPP 808
Score = 35.4 bits (80), Expect = 0.58
Identities = 77/334 (23%), Positives = 106/334 (31%), Gaps = 44/334 (13%)
Query: 1109 RGEDPPPDI--FAAADSKKSQP----KIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKP 1162
RG PP F A + P PP P G +G + P+ + G++ P
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP 924
Query: 1163 P----------TPASTPHSQIPPLPG-MSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGY 1211
P +P + + P PG + G+ + F + PG
Sbjct: 925 PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGK 984
Query: 1212 QPSMNTSDMM---GRMSYEPNKDPYGSMRK--APGSD--PFMSSGQGPNGGMGDPYSRAA 1264
Q S G M P G + APG++ P G G G+ A
Sbjct: 985 QGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET-GPAG 1043
Query: 1265 GPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMS-TGAPQPNLMPSNPDSGMYSPSR 1323
PG P P G DR T P GP G + GA P +G P
Sbjct: 1044 PPGAPGAPGAPGPVGPAGKSGDRGETGPA-GPAGPVGPVGARGP--------AGPQGPRG 1094
Query: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTS 1383
+ +Q + + QG P P + Q S PA P + +
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGE-----QGPSGASGPAGPRGPPGSAGA 1149
Query: 1384 PSKSPFLHSGMKMQKAGPPVPASHIAPA-PVQPP 1416
P K +G+ GPP P A PV PP
Sbjct: 1150 PGKDGL--NGLP-GPIGPPGPRGRTGDAGPVGPP 1180
Score = 32.7 bits (73), Expect = 3.8
Identities = 70/292 (23%), Positives = 88/292 (30%), Gaps = 68/292 (23%)
Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFN 1192
P G+ GPQ P+ + G+ PP PA A N
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG------------------AAGPAGN 387
Query: 1193 DGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252
G+D PG + + + G + + P G + PG P GP
Sbjct: 388 PGADG----------QPGAKGANGAPGIAGAPGFPGARGPSGP--QGPGGPP------GP 429
Query: 1253 NGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPG-IGPEGNM-STGAPQPNLM 1310
G G+P PG + P G V+ PG G EG + G P P +
Sbjct: 430 KGNSGEP----GAPGSKGDTGAKGEPGPVG-----VQGPPGPAGEEGKRGARGEPGPTGL 480
Query: 1311 PSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSS 1370
P P SR P D G GSP P+ S
Sbjct: 481 PGPPGERGGPGSRGFPGA--------DGVAGPKGPAG-ERGSPGPAGPK---------GS 522
Query: 1371 PAPLPRPMENRTSPSKSPFLHSGMKMQ--KAGPPVPASHIA-PAPVQPPMIR 1419
P RP E +K G K GPP PA P P PP R
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574
Score = 32.7 bits (73), Expect = 3.8
Identities = 53/232 (22%), Positives = 69/232 (29%), Gaps = 16/232 (6%)
Query: 1108 ERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAE------GGDLK 1161
++GE P ++ + P P G GP + E GD
Sbjct: 780 DKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAG 839
Query: 1162 PPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221
PP PA P P+ + + G + + + F PG +
Sbjct: 840 PPGPAG-PAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP 898
Query: 1222 GRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAA-GPGLGNVAMGPR---- 1276
G E K P G P P GP G G+ S A GP GP+
Sbjct: 899 GPAGKEGGKGPRG--ETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAG 956
Query: 1277 QHYPYGGPYDR-VRTEPGI-GPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPP 1326
Q G P R R PG+ GP G P P M P P
Sbjct: 957 QRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP 1008
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 112 bits (279), Expect = 5e-24
Identities = 244/1004 (24%), Positives = 314/1004 (31%), Gaps = 172/1004 (17%)
Query: 7 PAAASSLGNP----PPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA 62
P G+P PP PP + +R + G E G + GP
Sbjct: 639 PGEKGHRGDPGPSGPPGPPGD-----DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPP 693
Query: 63 VGPPQPLGKELQDGAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120
GPP G + Q G + N G G G G G PGA+ L G GP P L +P
Sbjct: 694 -GPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQ-GLPGPQGAIGP-PGEKGPLGKP 750
Query: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
G G+ G P H P G G P + P PG
Sbjct: 751 GLPGMPGAD---GPPGHPGKEGPPGEKGGQGPPGPQGPIGY-----------------PG 790
Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYN-SYYPNRSAYPPPAPAYALSSPRGGTP 239
++ G G+ G + + GFP + + +R PP P P G
Sbjct: 791 PRGVK--GADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPR-GEDGPEGPKG 847
Query: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG----GGPSAAG--GGTPQPTATP 293
G G PP R G G G P A G GG P
Sbjct: 848 RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPG 907
Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA 353
Q P+ RG +G G GP+ G GPA + G
Sbjct: 908 PRGQ--RGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGP 965
Query: 354 QQRSHHAPMSPGSSGGGGQPLARTPQ----PSSPMDQMGKMRPQ-PYGGTNPYSQQQGP- 407
P PG G G P R + P G + PQ P G T P ++ P
Sbjct: 966 -------PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018
Query: 408 PSGPQQGHGYPGQPYGSQTP-QRYPMTMQGR-AQSAMGGLSYTQQIP-PYGQQGPSGY-- 462
P GP G PG T P + G+ + G + +P P G G G
Sbjct: 1019 PPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG 1078
Query: 463 --GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ 520
G G ++ P +P Q P + P + PQ + + Q
Sbjct: 1079 PPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGL-Q 1137
Query: 521 QPSQPPHQQSPAPYPSQQSTTQQ--HPQSQPPYSQPQAQSPYQQQQPQ----QPAPSTLS 574
P P P P + + P + Q P PQ QP PS
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD 1197
Query: 575 QQAAYPQPQSQQS---QQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631
+ P P+ QQ Q+ + FP P G Q P KG D+
Sbjct: 1198 GE---PGPRGQQGLFGQKGDEGPRGFPGPP----GPVGLQGLPGPP--GEKGETGDVG-- 1246
Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS--SQGEQSNPAQSPFSPHTSPHL 689
Q P P G P G GA P GI + + GE+ P ++ P L
Sbjct: 1247 -QMGPPGPPGPRG-----PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAG-----EPGL 1295
Query: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRP--PSGQSDSIMHPS------- 740
PG GP P P G + SGP A PG + PP P G + P
Sbjct: 1296 PGEGGP-PGPKGERGE--KGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352
Query: 741 ---MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQ-------- 789
Q D+G + + Q SP P P P G + G +
Sbjct: 1353 PGPAGQDGPPGDKG---DDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGA 1409
Query: 790 QNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQP 845
+ G GP G G GPQG P +P + L P G+ G P G G M G P
Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGA-PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPM-GPP 1467
Query: 846 GIPPY--GTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHV 903
G+P + P G H + G+ PPG K
Sbjct: 1468 GLPGLKGDSGPKGEKGHPGL-----------------IGLIGPPGEQGEKGDR------- 1503
Query: 904 AANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPP 947
G P G +GP QGI +G I P GPP
Sbjct: 1504 ----------GLP----GPQGSSGPKGEQGITGPSGPIGPPGPP 1533
Score = 105 bits (263), Expect = 4e-22
Identities = 257/1020 (25%), Positives = 329/1020 (32%), Gaps = 154/1020 (15%)
Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG---------GGGG 86
G E A G M GQ + GPP G DG G GGGG
Sbjct: 472 GPEGPAGLPGPPGTM-GPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGG 530
Query: 87 GAGSGGG------PGAEPDLKNSN----GNAGPRPALNN-NLTEPPGGGG-GGSSDGVGA 134
AGS G A+ L+ + G AGP PPG GG G VG
Sbjct: 531 DAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGP 590
Query: 135 PPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ--HGGQQSPGLAALQSGGGGGL 192
P PA G+P GR A + A + Q G + GLA L G
Sbjct: 591 QGPRGVQGPPGPA---GKP-GRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRG 646
Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAAGSK 250
+P GP G + + P L P+G G PG +
Sbjct: 647 DP--GPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQ 704
Query: 251 PPPSSSASASSSSSSFAQQ-RFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSARG 307
P P + QQ GA G GP A G G P P L + A G
Sbjct: 705 PGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGM----PGADG 760
Query: 308 YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSS 367
G+PG + G + G GP A G + PG
Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF-PGFK 819
Query: 368 GGGGQPLARTP-QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPS-----GPQQGHGYPGQ- 420
G G R P P + G P+ GG N GPP G GYPG+
Sbjct: 820 GDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ 879
Query: 421 -PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSPHP 478
P GS +P A GG + P GQ+GP+G G++G + P
Sbjct: 880 GPKGSIGFPGFP-----GANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKG 934
Query: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ 538
+ P + P+ Q P P + P PP + +P Q+
Sbjct: 935 NSGGDGPAGPPGERGPNGP----QGPTGFPGP---------KGPPGPPGKDGLPGHPGQR 981
Query: 539 STTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ-QAAYPQPQSQQSQQTAYSQQRF 597
T ++ PP P PQ P T + +P P +Q
Sbjct: 982 GETGFQGKTGPP-------GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL------ 1028
Query: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGA 656
P ++ G++ P+ K G L+ P L G + L + G EG
Sbjct: 1029 --PGLAGKE--GTKGDPGPAGLPGKDGPP----GLRGFPGDR-GLPGPVGALGLKGNEGP 1079
Query: 657 LSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS------- 709
P G + S GE+ PA + P P PG +GP P P G + +
Sbjct: 1080 PGP----PGPAGSPGERG-PAGAA-GPIGIPGRPGPQGP-PGPAGEKGAPGEKGPQGPAG 1132
Query: 710 RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM-QRNPQMPQYSSPQPG 768
R G P +PG P PP D Q D+G P PQ QPG
Sbjct: 1133 RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG 1192
Query: 769 SALSPRQPSG-GQIHTGMGSYQQNSMGSYGPQG--------------------GQYGPQG 807
+ + +P GQ + G GP G GQ GP G
Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG 1252
Query: 808 GY-PRQPNYNALPNANYPSAGMAGGINPMGAGGQMH-----GQPGIPPYGTLPPGRMSHA 861
PR P+ P A+ P G GGI GA G+ G+PG+P G P +
Sbjct: 1253 PPGPRGPS--GAPGADGPQ-GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERG 1309
Query: 862 SMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMH-------VAANSIQNRPPG 914
G GP+ A PP G PPG K V + Q+ PPG
Sbjct: 1310 EKGES--GPSGAAGPP----GPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPG 1363
Query: 915 YPNMN----QGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMG 969
+ Q G G TG P G G P GP G A AG+ P G
Sbjct: 1364 DKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG 1423
Score = 101 bits (252), Expect = 7e-21
Identities = 211/897 (23%), Positives = 277/897 (30%), Gaps = 152/897 (16%)
Query: 14 GNPPPPPPSELKKAEQQQREEAGG-EAAAAAAAERGE-----MKAAAGQESEGPAVGPPQ 67
G PP P + + + A G E+GE K G + + +GPP
Sbjct: 776 GQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835
Query: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGAE-----PDLKNSNGNAGPRPALNNNLTEPPG 122
P G++ +G + GG G G G PG + P L G GP+ ++ P
Sbjct: 836 PRGEDGPEGPKGR-GGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK----GSIGFPGF 890
Query: 123 GGGGGSSDGVGAP----PHSAAAALPP-----PAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
G G G G P P P P G+P + S A +
Sbjct: 891 PGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950
Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS 233
G Q P G G + GP G P + + + ++ P P
Sbjct: 951 NGPQGP-------TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQG 1003
Query: 234 PRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTA 291
P G T G G PP + G G GP+ G G P
Sbjct: 1004 PTGETGPMGERGHPGPPGPPGEQGLPGLAGKE------GTKGDPGPAGLPGKDGPPGLRG 1057
Query: 292 TPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG 351
P ++ L P A G +G G GP +GPA A
Sbjct: 1058 FPG-DRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPA 1116
Query: 352 GAQ-QRSHHAPMSPGSSGGGGQPLARTPQPSSPM------DQMGKMRPQPYGGTNPYSQQ 404
G + P P G P+ P P+ P+ G++ G+ +
Sbjct: 1117 GEKGAPGEKGPQGPAGRDGLQGPVG-LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGE 1175
Query: 405 QGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQG--RAQSAMGGLSYTQQIPPYGQQG-P 459
QGP P+GPQ G PG P P QG + G + P G QG P
Sbjct: 1176 QGPPGPTGPQGPIGQPGPSGADGEPG--PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLP 1233
Query: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519
G++G+T Q P S P + P P P + + +P +
Sbjct: 1234 GPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVG---EKGEPGEA 1290
Query: 520 QQPSQPPHQQSPAPYPSQQSTTQQHPQSQ--------PPYSQPQAQSPYQQQQPQQPAPS 571
+P P P P + + P PP SP P P P
Sbjct: 1291 GEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGP- 1349
Query: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631
P P Q PP + D Q S P T G
Sbjct: 1350 -----PGEPGPAGQDG-----------PPGDKGDDGEPGQTGS-PGPTGEPG-------- 1384
Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQS-PFSPHTSPHLP 690
PS P G P G EG G G + P ++ P P +P P
Sbjct: 1385 ----PSGPPGKRGPPG--PAGPEGR----QGEKGAKGEAGLEGPPGKTGPIGPQGAPGKP 1434
Query: 691 ---GIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747
G+RG P PVG Q G P PG PP P + DS
Sbjct: 1435 GPDGLRG-IPGPVGE-----QGLPGSPGPDGPPGPMGPPGLPGLKGDS------------ 1476
Query: 748 QDRGYMQRNPQMPQYSSPQPG--SALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQY 803
P+ PG + P G + G+ Q GS GP+G G
Sbjct: 1477 -----------GPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ----GSSGPKGEQGIT 1521
Query: 804 GPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRM 858
GP G G P P LP P G G P G G+ G PG PP PPG +
Sbjct: 1522 GPSGPIGPPGPP---GLPGPPGPK-GAKGSSGPTGPKGEA-GHPG-PPGPPGPPGEV 1572
Score = 81.6 bits (200), Expect = 7e-15
Identities = 231/1029 (22%), Positives = 311/1029 (30%), Gaps = 175/1029 (17%)
Query: 8 AAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67
A S+ NP PPP E + EE + S +GP
Sbjct: 381 ADTSNSSNPAPPPGEGADDLEGEFTEET------IRNLDENYYDPYYDPTSSPSEIGPGM 434
Query: 68 PLGKELQDGAESNGGGGGGGAGSGG---------------GPGAEPDLKNSNGNAGPRPA 112
P QD GG G G G GP L G GP
Sbjct: 435 PAN---QDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQ 491
Query: 113 LNN-NLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSP--SAVAAAAAAVF 169
+ + PPG G +DG+ PP LP G G + P SA + A A+
Sbjct: 492 VGDPGERGPPGRPGLPGADGLPGPP-GTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAIL 550
Query: 170 HQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAY 229
Q + P +G G + GP + G P P R PP PA
Sbjct: 551 QQARLALRGPAGPMGLTGRPGPV----GPPGSGGLKGEPG-DVGPQGP-RGVQGPPGPA- 603
Query: 230 ALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288
G PG G A + G++ P + F + G G P
Sbjct: 604 -------GKPGRRGRAGSDGARGMPGQTGPKGDRG-------FDGLAGLPGEKGHRGDPG 649
Query: 289 PTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAA 348
P+ P G G G D GP+ GP +
Sbjct: 650 PSGPP----------GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVT 699
Query: 349 ASGGAQ-QRSHHAPMS-PGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQ 405
G + + P PG G G P A+ P P + G+ P G
Sbjct: 700 GMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGAD 759
Query: 406 GPPSGPQQGHGYPGQ-----PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPS 460
GPP P + G PG+ P G Q P YP + + GL T+ G++G
Sbjct: 760 GPPGHPGK-EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTK-----GEKGED 813
Query: 461 GY-GQQGQTPYYNQQS----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ 515
G+ G +G + P P+ + P + P+ P P +
Sbjct: 814 GFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGG-PNGDPGPLGPPGEKGKLGVPGL 872
Query: 516 PPYSQQPSQPPHQQSPA-PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ----QPAP 570
P Y + P P + + + P P Q P ++ P+ +P P
Sbjct: 873 PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932
Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630
S P ++ FP P+ P K G
Sbjct: 933 KGNSGGDGPAGPPGERGPNGPQGPTGFPGPK-------------GPPGPPGKDG------ 973
Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690
L P + P G G + P T G + GE+ +P P P LP
Sbjct: 974 -LPGHPGQRGETGFQGKTGPPGPPGVVGPQGPT-GETGPMGERGHPG--PPGPPGEQGLP 1029
Query: 691 GIRGPS-----PSPVGSPASVA----------QSRSGPLSPAAVPGNQMPPRPPS-GQSD 734
G+ G P P G P + GP+ + GN+ PP PP S
Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089
Query: 735 SIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMG 794
P+ I + P P PG P+ P+G G+ Q +G
Sbjct: 1090 GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEK-GPQGPAG---RDGL----QGPVG 1141
Query: 795 SYGPQG-----GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI 847
GP G G+ G +G G P Q G G P G G + GQPG
Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKG-------DKGEQGPPGPTGPQGPI-GQPGP 1193
Query: 848 PPYGTLPPGRMSHASMGNR-PYGPNMANMPP-QVGSGMCPPPGGMNRKTQETAVAMHVAA 905
P R G + GP PP VG P P G +T +
Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVG------- 1246
Query: 906 NSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMA---NNSAGMA 962
Q PPG PP +G + G PQGPP +G A G A
Sbjct: 1247 ---QMGPPG-------------PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEA 1290
Query: 963 ASPEMMGLG 971
P + G G
Sbjct: 1291 GEPGLPGEG 1299
Score = 59.7 bits (143), Expect = 3e-08
Identities = 137/602 (22%), Positives = 194/602 (32%), Gaps = 127/602 (21%)
Query: 478 PQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ 537
PQ Q P + + Y + P + P+ +P S++P + + + P
Sbjct: 252 PQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELT 311
Query: 538 QSTTQQHPQSQP------------------PYSQPQAQSPYQ-------QQQPQQPAPST 572
+ T+ P + P SPY ++ P QP
Sbjct: 312 PTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPT--- 368
Query: 573 LSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSL 632
A P S + T+ S PPP E + D G + ++ + D
Sbjct: 369 -DPGAGAEIPTS--TADTSNSSNPAPPPGEGADDLEGE--FTEETIRNLDENYYDPYYDP 423
Query: 633 QSRPSSL-PDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPA-----------QSP 680
S PS + P + + D + G G +G++ PA P
Sbjct: 424 TSSPSEIGPGMPANQDTIYEG----------IGGPRGEKGQKGEPAIIEPGMLIEGPPGP 473
Query: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPP----------S 730
P P PG GP+ VG P GP +PG P PP
Sbjct: 474 EGPAGLPGPPGTMGPT-GQVGDP-----GERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527
Query: 731 GQSDSIMHPSMNQSSIAQDRGYMQ------RNPQMPQYSSPQPGSA-------------- 770
G D+ M + +Q + +Q R P P + +PG
Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587
Query: 771 LSPRQPSGGQIHTGMGSY--QQNSMGSYGPQG--GQYGPQG--------GYPRQPNYNAL 818
+ P+ P G Q G ++ GS G +G GQ GP+G G P + +
Sbjct: 588 VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647
Query: 819 PNANYPSAGMAGGINPMGAGGQM--HGQPGIP-PYGTL-------PPGRMSHASMGNRPY 868
P + P G G G G++ G PG P P G L PPG M +P
Sbjct: 648 PGPSGP-PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQP- 705
Query: 869 GPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT-G 927
GP N+ PQ G PP N Q + P G P + GM G G
Sbjct: 706 GPK-GNVGPQGEPG--PPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGL--PGMPGADG 760
Query: 928 PPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADG 987
PP G G QGPP G G+ + + GL TK DG
Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGL------KGTKGEKGEDG 814
Query: 988 TP 989
P
Sbjct: 815 FP 816
Score = 53.1 bits (126), Expect = 3e-06
Identities = 97/426 (22%), Positives = 138/426 (32%), Gaps = 85/426 (19%)
Query: 525 PPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584
P QS P P + T Y P + P + ++P PS +AA
Sbjct: 249 PDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDP--EDLGKEPTPSKKPVEAA------ 300
Query: 585 QQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG 644
+ T ++ P P E A+ P + G +ED+ + G
Sbjct: 301 --KETTEVPEELTPTPTE---------AAPMPETSEGAGKEEDVGI-------------G 336
Query: 645 SIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPA 704
D +P SP ++ +GE+ NP Q P+ G+ A
Sbjct: 337 DYDYVPSEDYYTPSP---YDDLTYGEGEE-NPDQ------------------PTDPGAGA 374
Query: 705 SVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSS 764
+ S A N P PP G+ + + +I + N P Y
Sbjct: 375 EIPTS-------TADTSNSSNPAPPPGEGADDLEGEFTEETIRN----LDENYYDPYYDP 423
Query: 765 PQPGSALSPRQPSGGQ-IHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNA 821
S + P P+ I+ G+G GP+G GQ G P
Sbjct: 424 TSSPSEIGPGMPANQDTIYEGIG----------GPRGEKGQKGEPAIIEPGMLIEGPPGP 473
Query: 822 NYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPN-MANMPPQVG 880
P AG+ G MG GQ+ G PG PPGR P P M +P + G
Sbjct: 474 EGP-AGLPGPPGTMGPTGQV-GDPGERG----PPGRPGLPGADGLPGPPGTMLMLPFRFG 527
Query: 881 SGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGM 940
G G QE+ + + R P P G GPP G+ G
Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587
Query: 941 INPQGP 946
+ PQGP
Sbjct: 588 VGPQGP 593
Score = 52.4 bits (124), Expect = 5e-06
Identities = 174/805 (21%), Positives = 242/805 (30%), Gaps = 152/805 (18%)
Query: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGG----------GPSAAGGGTPQ 288
P S A + S P P A F ++ + PS G G
Sbjct: 377 PTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPG--M 434
Query: 289 PTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAG-KGPADMASQCWGAAAAAAAAA 347
P T+ + + P +G +G P G +G G +GPA + G
Sbjct: 435 PANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP----GPPGTMGPTG 490
Query: 348 AASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407
++ P PG+ G P P M M P +GG + +GP
Sbjct: 491 QVGDPGERGPPGRPGLPGADG--------LPGPPGTM----LMLPFRFGGGGD-AGSKGP 537
Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ 467
Q+ Q+ + ++G A G + T + P G G G +G+
Sbjct: 538 MVSAQESQA-------QAILQQARLALRGPA----GPMGLTGRPGPVGPPGSGGL--KGE 584
Query: 468 TPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH 527
Q P Q P + +P + + P P+ + P + H
Sbjct: 585 PGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH 644
Query: 528 QQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS 587
+ P P + P+ P +P P L P P
Sbjct: 645 RGDPGPSGPPGPPGDDGERGDDGEVGPRGL-------PGEPGPRGLLGPKGPPGPPG--- 694
Query: 588 QQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID 647
PP D KG N+ Q P
Sbjct: 695 -----------PPGVTGMDG----------QPGPKG-----NVGPQGEPG---------- 718
Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQS-PFSPHTSPHLPGIRGPS--PSPVGSPA 704
P G +G +PG G+ QG P + P P +PG GP P G P
Sbjct: 719 --PPGQQG--NPGAQ--GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPG 772
Query: 705 SVA-QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD-----RGYMQRNPQ 758
Q GP P PG PR G +D I + +D +G M
Sbjct: 773 EKGGQGPPGPQGPIGYPG----PRGVKG-ADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 827
Query: 759 MPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG--GYP-RQP 813
+ P P P P G G G GP G G+ G G GYP RQ
Sbjct: 828 RGEIGPPGPRGEDGPEGPKGRGGPNG-------DPGPLGPPGEKGKLGVPGLPGYPGRQG 880
Query: 814 NYNALPNANYPSA-------GMAGGINPMGAGGQMHGQPGIPPYG-TLPPGRMSHASMGN 865
++ +P A G G P G G + P G T PG ++ G+
Sbjct: 881 PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSG-GD 939
Query: 866 RPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-----QNRPPGYPNM 918
P GP P PQ +G P P G + + H + PPG P +
Sbjct: 940 GPAGPPGERGPNGPQGPTGF-PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998
Query: 919 -------NQGGMMGT-------GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAAS 964
+ G MG GPP QG+ +AG +G P G + G+
Sbjct: 999 VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF 1058
Query: 965 PEMMGLGDVKLTPATKMNNKADGTP 989
P GL K N G P
Sbjct: 1059 PGDRGLPGPVGALGLKGNEGPPGPP 1083
Score = 38.5 bits (88), Expect = 0.069
Identities = 58/256 (22%), Positives = 82/256 (32%), Gaps = 17/256 (6%)
Query: 1106 KIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTP 1165
K E+GED P K + +I PP P G GP+ P+ + G L P P
Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGE---DGPEGPKGRGGPNGDPGPLGP--P 861
Query: 1166 ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTP-NPGYQPSMNTSDMMGRM 1224
+P LPG F + +K TP PG + + G
Sbjct: 862 GEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGER 921
Query: 1225 SYEPNKDPYGSMRKAPGSDPFMSSGQ-GPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGG 1283
G + G P G+ GPNG P PG P + G
Sbjct: 922 GPRGITGKPGPKGNSGGDGPAGPPGERGPNG----PQGPTGFPGPKGPPGPPGKDGLPGH 977
Query: 1284 PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP--DSGMYSPSRYPPQQQQQQQQRHDSYGN 1341
P R T G +G P + P P ++G +P +Q
Sbjct: 978 PGQRGET----GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG 1033
Query: 1342 QFSTQGTPSGSPFPSQ 1357
+ T+G P + P +
Sbjct: 1034 KEGTKGDPGPAGLPGK 1049
Score = 32.0 bits (71), Expect = 6.4
Identities = 65/266 (24%), Positives = 86/266 (32%), Gaps = 64/266 (24%)
Query: 1106 KIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTP 1165
K ++GE PP Q I P P+G+ GP+ Q + G P P
Sbjct: 1170 KGDKGEQGPPG------PTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGP 1223
Query: 1166 ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS 1225
PG VG+Q + PG + MG
Sbjct: 1224 -----------PG-----PVGLQ---------------GLPGPPGEKGETGDVGQMGPPG 1252
Query: 1226 YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYS--------RAAGPGLGNVA----- 1272
+ P G APG+D QGP GG+G+P + A PGL
Sbjct: 1253 PPGPRGPSG----APGAD----GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGP 1304
Query: 1273 MGPRQHYPYGGPYDRVRTEPGIGPEGNMS-TGAPQPNLMPSNP-DSGMYSPSRYPPQQQQ 1330
G R GP GP G+ G+P P P +P G P+ Q
Sbjct: 1305 KGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPA---GQDGP 1361
Query: 1331 QQQQRHDSYGNQFSTQGTPSGSPFPS 1356
+ D Q + G P+G P PS
Sbjct: 1362 PGDKGDDGEPGQTGSPG-PTGEPGPS 1386
Score = 32.0 bits (71), Expect = 6.4
Identities = 17/46 (36%), Positives = 19/46 (41%), Gaps = 6/46 (13%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLP 1177
PP P G+ GP P+ E G PP P P I PLP
Sbjct: 1538 PPGPKGAKGSSGPTGPKG------EAGHPGPPGPPGPPGEVIQPLP 1577
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 107 bits (268), Expect = 9e-23
Identities = 229/1038 (22%), Positives = 351/1038 (33%), Gaps = 123/1038 (11%)
Query: 21 PSELKKAEQQQREEAGGE--AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAE 78
PS ++ + G+ + ++ + RG ++ +GQ S G Q Q
Sbjct: 307 PSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTS-----GFGQHESGSGQSSGY 361
Query: 79 SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138
S G G G + S G G+ +S+G G +++ G S G HS
Sbjct: 362 SKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSY----GQHESASRHSSGRGQHS 417
Query: 139 AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP 198
+ + G+SP H Q G ++ Q G G G +GP
Sbjct: 418 SGS-------------GQSPG----------HGQRGSGSGQSPSSGQHGTGFGRSSSSGP 454
Query: 199 --QQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS 256
+ + GF +H+ +S + S Y SS G ++ G +
Sbjct: 455 YVSGSGYSSGFGHHESSS--EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGER-----Q 507
Query: 257 ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ-PTATPTLNQLLTSPSSARGYQGYPGG- 314
S++ SSSS+ Q G+ G S G G+ Q P+ + ++ + SS+ G GY G
Sbjct: 508 GSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGR 567
Query: 315 DYSGGPQDGGAG--KGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372
S GP + G+G G S+ G ++ ++SG + H S G S GQ
Sbjct: 568 SSSRGPYESGSGHSSGLGHQESRS-GQSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQ 625
Query: 373 PLARTPQPSS-PMDQMGKMRPQPYG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQ 425
A + Q SS G + YG G +P + G G +G G G
Sbjct: 626 HGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS 685
Query: 426 TPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG-----PSGYGQQGQTPYYNQQSPHPQQ 480
+ ++ G++ S G S + Q Y Q G SGY + G + +S +
Sbjct: 686 SSNGPHGSVSGQS-SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRS----E 740
Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540
Q S S H S+Q + P + S H S + S S
Sbjct: 741 QHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSC 800
Query: 541 T-----------------QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583
+ Q S YSQ + S + Q + ST Q ++ Q
Sbjct: 801 SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRH--GSTSGQSSSSGQHD 858
Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAP--SMTSSKGGQEDMNLSLQSRPSSLPD 641
S Q ++Y Q + GS + +P S GQ PS
Sbjct: 859 SSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQS---------PSYGRH 909
Query: 642 LSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQ--------SPFSPHTSPHLPGIR 693
SGS G G+ S S G SS G+ S Q S + H S R
Sbjct: 910 GSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969
Query: 694 GPS-PSPVGSPASVAQSRSGPLSPAA----VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQ 748
S GS +S Q SG G+ P P G+ S S +
Sbjct: 970 SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029
Query: 749 DRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGG 808
G+ + + P S S L R+ GQ G Q S + GQ+G G
Sbjct: 1030 GSGW--SSSRGPYESGSGHSSGLGHRESRSGQ---SSGYGQHGSSSGHSSTHGQHGSTSG 1084
Query: 809 YPRQPNYNALPNANYPSAGM--AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866
+ + S G +G G G Q G P +G G S G
Sbjct: 1085 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144
Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY-PNMNQGGMMG 925
G ++ Q GSG+ G + ++ + + S GY + ++ G
Sbjct: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1204
Query: 926 TGPPYG--QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNN 983
G +G G +S G + G S G + +G + S G G L ++
Sbjct: 1205 RGERHGSSSGSSSHYGQ-HGSGSRQSSGHGRQGSGSGHSPSRGRHGSG---LGHSSSHGQ 1260
Query: 984 KADGTPKTESKSKKSSSS 1001
G+ ++ S+ S S
Sbjct: 1261 HGSGSGRSSSRGPYESRS 1278
Score = 100 bits (250), Expect = 1e-20
Identities = 233/1070 (21%), Positives = 349/1070 (32%), Gaps = 137/1070 (12%)
Query: 33 EEAGGEAAAAAAAERGEMKAAAGQ-ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG 91
+ G + ++ + G + + E G + G G+ G+ + G G G+GSG
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH-GSGSHQSSGHGRQGSGSG 773
Query: 92 GGP-----GAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS-------DGVGAPPH-- 137
P G+ +S+G G + +++ G G S G G H
Sbjct: 774 HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833
Query: 138 -----------------SAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
S+++ + G YG+ SA A+ H GQ SPG
Sbjct: 834 ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ-SPG 892
Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
Q G G G P G + + ++ S S + + + S G
Sbjct: 893 HG--QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSG 950
Query: 241 SGAAAAA---GSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293
SG +++ GS+ SS + S+S SSSS+ Q G+ G G G+ Q
Sbjct: 951 SGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ----- 1005
Query: 294 TLNQLLTSPSSARGYQGYPGGDYSG-GPQDGGAG----KGPADMAS----------QCWG 338
SPS +RG G G S GP G+G +GP + S G
Sbjct: 1006 -------SPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1058
Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQ-MGKMRPQPYGG 397
++ ++SG + H S G S GQ A + Q SS G + YG
Sbjct: 1059 QSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG- 1116
Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL------------ 445
+QG SG GHG G GS+ Y G +S+ G
Sbjct: 1117 ------RQGSGSGQSPGHGQRGS--GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1168
Query: 446 ---SYTQQIPPYGQQGP-----SGYGQQGQTPYYNQQ---------SPHPQQQQPPYSQQ 488
S + Q Y Q G SGYGQ G + + S Q S+Q
Sbjct: 1169 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228
Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ---STTQQHP 545
S + + + Q S S PY S+ S QH
Sbjct: 1229 SSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1288
Query: 546 QSQ---PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602
YSQ + S + Q Q ST Q + + Q S Q ++Y + Q
Sbjct: 1289 SGSGHSSAYSQHGSGSGHFCSQGQHG--STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQS 1346
Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
G+ + +PS G + Q S S G S
Sbjct: 1347 SGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES 1406
Query: 663 TSGISS--SQGEQSNPAQSPFSPHTSPHLPGIRGPSP-SPVGSPASVAQSRSGPLSPAAV 719
+S SS +Q + S + H S RG S GS +S Q SG
Sbjct: 1407 SSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGH 1466
Query: 720 ----PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQ 775
G+ P P G+ S S + S G+ + + P S S L R+
Sbjct: 1467 GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWS--SSRGPYESGSSHSSGLGHRE 1524
Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGM--AGGIN 833
GQ G Q S + GQ+G G + + S G +G
Sbjct: 1525 SRSGQ---SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1581
Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893
G G Q G P +G G S G G ++ Q GSG+ G + +
Sbjct: 1582 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 1641
Query: 894 TQETAVAMHVAANSIQNRPPGY-PNMNQGGMMGTGPPYGQGINSMAGM-INPQGPPYSMG 951
+ + + S GY + ++ G G +G S + + G S G
Sbjct: 1642 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG 1701
Query: 952 GTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSS 1001
+ +G + S G G L ++ G+ ++ S+ S S
Sbjct: 1702 HGRQGSGSGQSPSRGRHGSG---LGHSSSHGQHGSGSGRSSSRGPYESRS 1748
Score = 100 bits (248), Expect = 2e-20
Identities = 230/1005 (22%), Positives = 335/1005 (33%), Gaps = 163/1005 (16%)
Query: 31 QREEAGGEAAAAAA--------AERGEMKAAAGQES----EGPAVGPPQPLGKELQDGAE 78
Q E G ++A + +G+ + +GQ S EG + G G+ ++
Sbjct: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
Query: 79 SNG----GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134
S+ G G G + S G G+ +S G G +++ G G G S G G
Sbjct: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH--GSGSGQSSGFGH 1873
Query: 135 PPHSAAAALPPPAYGFGQPYG--------------RSPSAVAAAAAAVFHQQHGGQQSPG 180
S+ + +G G + R +++ ++ + QHG
Sbjct: 1874 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQS 1933
Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG-TP 239
L Q G G G P P + H G S+Y P SS RG
Sbjct: 1934 LGHGQHGSGSGQSP--SPSRGRHGSGSGQS---------SSYGPYGSGSGWSSSRGPYES 1982
Query: 240 GSGAAAAAGSKPPPSSSAS------ASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293
GSG ++ G + S +S +SS SS Q A G G + +++
Sbjct: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042
Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDG------------GAGKGPADMASQCW---G 338
+ +S SS G QG G G Q G G+G G + + Q G
Sbjct: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102
Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398
++ ++SG + S H S G S G GQ +R+ Q S G+ G +
Sbjct: 2103 ESSGFGHHESSSGQSSSYSQHGSGS-GHSSGYGQHGSRSGQSSR-----GERHGSSSGSS 2156
Query: 399 NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG 458
+ Y Q G S GHG G G +P R GR S G S +GQ G
Sbjct: 2157 SRYGQH-GSGSRQSSGHGRQGSGSG-HSPSR------GRHGSGSGHSS------SHGQHG 2202
Query: 459 PSGYGQQGQTPYYNQQSPHPQQ--QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516
SG G+ Y +S H Q S + + H S Q Q
Sbjct: 2203 -SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2261
Query: 517 PYSQQPSQPPHQQSPAPYPSQQSTTQQHPQS------QPPYSQPQAQSPYQQQQPQQPAP 570
+ Q+ S S + S S + + Q P + + S + Q +
Sbjct: 2262 TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 2321
Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630
S S + S QS + + +Q GS SS+ S+ GQ
Sbjct: 2322 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS---- 2377
Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690
S R S S S G+ +L G SG QSP SP H
Sbjct: 2378 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG----------SGQSP-SPSRGRHGS 2426
Query: 691 GI-RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749
G + S SP GS + + SR P SG S + H +S Q
Sbjct: 2427 GSGQSSSYSPYGSGSGWSSSRG-------------PYESGSGHSSGLGH---RESRSGQS 2470
Query: 750 RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGY 809
GY Q S+ + S + S GQ G S Q +S G +G Q GY
Sbjct: 2471 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ--HGASSGQSSSHGQHGSGSSQ---SSGY 2525
Query: 810 PRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYG 869
RQ G G +P HGQ G G S G G
Sbjct: 2526 GRQ--------------GSGSGQSPG------HGQRG--------SGSRQSPSYGRHGSG 2557
Query: 870 PNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY-PNMNQGGMMGTGP 928
++ Q GSG+ G + ++ + + S GY + ++ G G
Sbjct: 2558 SGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE 2617
Query: 929 PYG--QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971
+G G +S G + G S G + +G + S G G
Sbjct: 2618 RHGSSSGSSSHYGQ-HGSGSRQSSGHGRQGSGSGQSPSRGRHGSG 2661
Score = 90.1 bits (222), Expect = 2e-17
Identities = 236/1078 (21%), Positives = 357/1078 (33%), Gaps = 147/1078 (13%)
Query: 26 KAEQQQREEAGGEAAAAAAA--ERGE-MKAAAGQESEGPAVGP-PQPLGKELQDGAESNG 81
++ Q R E G +A ++++ + G + + G G G P P + G+ +
Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556
Query: 82 GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAP--PHSA 139
G G GSG P ++ +G++ + + G G GSS G + H +
Sbjct: 557 SYGPHGYGSGRSSSRGP-YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
Query: 140 AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQ 199
+ G G+S S H QHG S Q G G G P G
Sbjct: 616 TSGQSSSCGQHGATSGQSSS----------HGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
Query: 200 QNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA------------- 246
+ H Q+ S S+ P SS G GSG ++
Sbjct: 666 GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG 725
Query: 247 ---AGSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP---------- 289
GS+ SS + S+S SSS+ Q G+ G G G+
Sbjct: 726 YRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785
Query: 290 --TATPTLNQLLTSPSSARGYQGYPGGDYSG-GPQDGGAGKGPADMAS------------ 334
+++ + TS SS+ G+ G SG G + G+G+G + S
Sbjct: 786 GHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG 845
Query: 335 QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQP 394
G ++++ ++SG + H S +SG G P G +
Sbjct: 846 STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905
Query: 395 YG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448
YG G + S + G SG G G+ S Y G S+ SY
Sbjct: 906 YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKS---SSGQSSGYTQHGSGSGHSS----SYE 958
Query: 449 QQIPPYGQQ-----------GPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497
Q GQ S YGQ G Q H Q PS+ H
Sbjct: 959 QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRHGS 1016
Query: 498 PSYQQQ---PQSQPPQLQSSQPPY---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQ 548
S Q P SS+ PY S S H++S + S Q ++ H +
Sbjct: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
Query: 549 PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608
+ QS Q ++ Q +++ Q S SQ + Y +Q Q
Sbjct: 1077 GQHGSTSGQSSSCGQH-----GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1131
Query: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG-SIDDLPMGTEGALSPGVSTSGIS 667
GS + +PS G + S S L + SG + G + S S SG S
Sbjct: 1132 GSGSRQSPSY-GRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPR 727
S G+ ++S S H G S S G S ++ SG + G+ P R
Sbjct: 1191 SGYGQHG--SRSGQSSRGERH--GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS-PSR 1245
Query: 728 PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG- 786
G S + + Q + SS P + S GQ +G G
Sbjct: 1246 GRHG------------SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293
Query: 787 --SYQQNSMGS-YGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843
+Y Q+ GS + GQ+G G + S G G + +G HG
Sbjct: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 1353
Query: 844 QPG--IPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK-------- 893
P G G +S G G ++ + GSG G + +
Sbjct: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
Query: 894 -TQETAVAMHVAANSIQNRPPGYPNMNQ--GGMMGTGPPYGQ-GINS-------MAGMIN 942
TQ + + H ++ G + + G G+ YGQ G S G +
Sbjct: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLG-DVKLTPATKMNNKADGTPKTESKSKKSS 999
Q P S G + + + SP G G P ++ + G ES+S +SS
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSS 1531
Score = 85.9 bits (211), Expect = 4e-16
Identities = 197/889 (22%), Positives = 310/889 (34%), Gaps = 113/889 (12%)
Query: 150 FGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP------QQNSH 203
F + + ++ + +++ Q QS G Q G G G P G Q +S+
Sbjct: 161 FQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRG--QCGSGSGQSPNYGQHGSGSGQSSSN 218
Query: 204 D-HGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGA-AAAAGSKPPPSSSASASS 261
D HG + Q + + ++S+ + S G + G G + +G S+S
Sbjct: 219 DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSG 278
Query: 262 SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG-DYSGGP 320
SSSS+ Q G+ G G G+ Q + + + + SS+ G G YS G
Sbjct: 279 SSSSYGQHGSGSRQSLGHGRQGSGSRQ-SPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGH 337
Query: 321 QDGGAGK----GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR 376
+ G+G+ G + S G ++ + + SG + + H S G + GQ +
Sbjct: 338 YESGSGQTSGFGQHESGS---GQSSGYSKHGSGSGHSSSQGQHGSTS-GQASSSGQHGSS 393
Query: 377 TPQPSS-------PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQR 429
+ Q SS G+ + G +P Q+G SG G G +G +
Sbjct: 394 SRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSG 453
Query: 430 YPMTMQGRAQSAMGGLSYTQQIPPYGQQG-----PSGYGQQ-----------------GQ 467
++ G + S ++ Y Q G SG+GQ G
Sbjct: 454 PYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGS 513
Query: 468 TPYYNQQSPHPQQ-----QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ-----LQSSQPP 517
+ Y Q +Q + S Q PS + S +Q S P SS+ P
Sbjct: 514 SSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGP 573
Query: 518 Y---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPS 571
Y S S HQ+S + S Q ++ H + + QS Q +
Sbjct: 574 YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH-----GA 628
Query: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631
T Q +++ Q S SQ + Y QQ Q S+ GS SS GQ
Sbjct: 629 TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGH-----SSSYGQHGSGSG 683
Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVST--SGISSSQGEQSNPAQSPFSPHTSPHL 689
S +SG + S G S SG S S G + + ++S S + H
Sbjct: 684 WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQH- 742
Query: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749
G S G S + SG + G+ P R G S S + SS Q
Sbjct: 743 -GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHS-PSRVRHGSS------SGHSSSHGQH 794
Query: 750 RGYMQRNPQMPQYSSPQ-PGSALSPRQPSGGQIHT--GMGSYQQNSMGSYGPQGGQYGPQ 806
+ Y S S + GQ ++ G S +S G +G GQ
Sbjct: 795 GSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854
Query: 807 GGYPRQPNYNALPNANYPSAGMAGGINPMGAG-GQM--HGQPG-----IPPYGTLPPGRM 858
G + ++ + ++ A G G+G GQ HGQ G P YG G
Sbjct: 855 GQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914
Query: 859 SHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNM 918
+S G G ++ G G G + TQ + + H ++ G +
Sbjct: 915 RSSSSGRHGSGSGQSS-----GFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969
Query: 919 NQ--GGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP 965
++ G G+ YGQ + G S+G + +G + SP
Sbjct: 970 SEQHGSSSGSSSSYGQ---------HGSGSRQSLGHGQHGSGSGQSPSP 1009
Score = 85.5 bits (210), Expect = 5e-16
Identities = 203/918 (22%), Positives = 299/918 (32%), Gaps = 138/918 (15%)
Query: 14 GNPPPPPPSELKKAEQQQREEAGGEAAAAA--AAERGEMKAAAGQES--------EGPAV 63
G+ P PS + + + G + + ++ RG ++ +G S G +
Sbjct: 1942 GSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS 2001
Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGG 123
G Q G G + S G GA +S+G G + ++ G
Sbjct: 2002 GYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ--G 2059
Query: 124 GGGGSSDGVGAPPHSAAAALPPPAYG-FGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLA 182
G G S G G + + P+YG G GRS S+ GQ PGL
Sbjct: 2060 SGSGQSPGHG---QRGSGSRQSPSYGRHGSGSGRSSSS--------------GQHGPGLG 2102
Query: 183 ALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSS---PRGG 237
+S G G E +G + HG + + Y + +RS + SS R G
Sbjct: 2103 --ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG 2160
Query: 238 TPGSGAAAAAG-------SKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPT 290
GSG+ ++G S PS S S S + + G+ G G S++ G +
Sbjct: 2161 QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGS--GSGRSSSRGPYESRS 2218
Query: 291 ATPTL---NQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAA 347
++ ++ + SSA G G + Q G G ++
Sbjct: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS-----------GQSSTFDQEG 2267
Query: 348 AASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYG------GTNPY 401
+++G + H S SS G Q PS G YG G +
Sbjct: 2268 SSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 2327
Query: 402 SQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG--- 458
S + G SG G G+ + S + Q T G SY Q GQ
Sbjct: 2328 SGRHGSGSGQSSGFGH----HESSSWQSSGYTQHGSGSGHSS--SYEQHGSRSGQSSRGE 2381
Query: 459 --------PSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQ---PQSQ 507
S YGQ G Q H Q PS+ H S Q P
Sbjct: 2382 RHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS 2439
Query: 508 PPQLQSSQPPY---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQPPYSQPQAQSPYQ 561
SS+ PY S S H++S + S Q ++ H + + QS
Sbjct: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 2499
Query: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSM--- 618
Q ++ Q +++ Q S SQ + Y +Q Q GS + +PS
Sbjct: 2500 GQHG-----ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554
Query: 619 -----TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGALSPGVSTSGISSSQGE 672
SS GQ L S SG G+ S G G S Q
Sbjct: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2614
Query: 673 QS--NPAQSPFSPHTSPHLPGIR------------GPSPSP------VGSPASVAQ--SR 710
+ + + S S H H G R G SPS +G +S Q S
Sbjct: 2615 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 2674
Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP----- 765
SG S +++ GQ +S S S G+ Q S
Sbjct: 2675 SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2734
Query: 766 QPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPS 825
Q GS+ G H G GS Q + G +G GQ G + ++ +
Sbjct: 2735 QEGSSTGQSSSYG---HRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSG 2791
Query: 826 AGMAGGINPMGAGGQMHG 843
+G + G + G+G G
Sbjct: 2792 SGQSSGYSQHGSGSGQDG 2809
Score = 84.3 bits (207), Expect = 1e-15
Identities = 197/808 (24%), Positives = 267/808 (33%), Gaps = 115/808 (14%)
Query: 52 AAAGQESEGPAVGPPQPLGK-ELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR 110
+++GQ GP +G G E G S+ G G+G G G ++ + G R
Sbjct: 2092 SSSGQH--GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS-RSGQSSRGER 2148
Query: 111 PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170
++ + G G GS G H G G SPS + +
Sbjct: 2149 HGSSSGSSSRYGQHGSGSRQSSG---HGRQ----------GSGSGHSPSRGRHGSGSGHS 2195
Query: 171 QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA-- 228
HG Q G G G GP ++ H Q+ S + SAY
Sbjct: 2196 SSHG----------QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 2245
Query: 229 -YALSSPRGGTPG-SGAAAAAGSKPPPSSS----ASASSSSSSFAQQRFGAMGGGGPSAA 282
+ G T G S GS SSS S SS SSS+ QQ G+ G PS
Sbjct: 2246 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ--GSGSGQSPSRG 2303
Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342
G+ ++ S G+ G SG Q G G S W ++
Sbjct: 2304 RHGSGSGHSSS-----YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE----SSSW-QSSG 2353
Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402
+ SG + H S SS G + S G + +G S
Sbjct: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413
Query: 403 QQQGPPSGPQQGHGYPGQ-----PYGSQTPQRYPMTMQGRAQSAMG---GLSYTQQIPPY 454
Q PS + G G GQ PYGS + + +G +S G GL + +
Sbjct: 2414 GQSPSPSRGRHGSG-SGQSSSYSPYGSGSGWS---SSRGPYESGSGHSSGLGHRESRS-- 2467
Query: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS 514
GQ SGYGQ G + ++ S H Q S Q S H S Q Q S
Sbjct: 2468 GQS--SGYGQHGSSSGHS--STHGQHGST--SGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521
Query: 515 QPPYSQQPS----QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570
Y +Q S P H Q + S + S S Q S +
Sbjct: 2522 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 2581
Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630
S+ Q ++Y Q S + Y Q Q + GS + S SS GQ
Sbjct: 2582 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS-----SSHYGQHGSG- 2635
Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGI--SSSQGEQSNPAQSPFSPHTSPH 688
SR SS GS G+ + S G SG+ SSS G+ + + S
Sbjct: 2636 ---SRQSSGHGRQGS------GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS------ 2680
Query: 689 LPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN---------QMPPRPPSGQSDSIMHP 739
RGP S +G + Q SG +A + Q SGQS +
Sbjct: 2681 ----RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF--- 2733
Query: 740 SMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQ 799
SS Q Y R Q S A S + S G+ +G G SYG
Sbjct: 2734 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQ-----SSSYGQH 2788
Query: 800 GGQYGPQGGYPRQPNYNALPNANYPSAG 827
G G GY + + + +Y G
Sbjct: 2789 GSGSGQSSGYSQHGSGSGQDGYSYCKGG 2816
Score = 79.3 bits (194), Expect = 4e-14
Identities = 204/937 (21%), Positives = 286/937 (30%), Gaps = 173/937 (18%)
Query: 54 AGQESEGPAVGPPQPLGKEL-QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPA 112
+GQ S G G Q G+ S G G GSG G P S G G
Sbjct: 1434 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP----SRGRHGSGSG 1489
Query: 113 LNNNLTEPPGGGGGGSSDGV--GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170
+++ + G G SS G HS+ G YG+ S+ ++ H
Sbjct: 1490 QSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST---H 1546
Query: 171 QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSH-DHGFPNHQYNSY------------YP 217
QHG + Q G G Q +SH HG + Q + Y +
Sbjct: 1547 GQHGSTSGQSSSCGQHGASSG-------QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 1599
Query: 218 NRSAYPPPAPAYALS------SPRGGTPGSGAAAAAGSKPPPSSSASASS---------- 261
R + +P+Y S G GSG ++G SSS +SS
Sbjct: 1600 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1659
Query: 262 -------------------------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLN 296
SSS + Q G+ G G G+ Q
Sbjct: 1660 SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQ-------- 1711
Query: 297 QLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQR 356
SPS R G G S G G+G+ +++ G + R
Sbjct: 1712 ----SPSRGRHGSGL-GHSSSHGQHGSGSGR-------------------SSSRGPYESR 1747
Query: 357 SHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHG 416
S H+ + G G A + S + + G + Q+G +G HG
Sbjct: 1748 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 1807
Query: 417 YPGQPYGSQTPQRYPMTMQGRAQSAMGGL--SYTQQIPPYGQQGP------------SGY 462
G GS Y G QS G S + YGQ G SG
Sbjct: 1808 QHGS--GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865
Query: 463 GQQGQTPYYNQQS--PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ 520
GQ ++ S Q S S H S Q Q S Y Q
Sbjct: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ 1925
Query: 521 QPSQPPHQ-----------QSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569
S QSP+P + + S PY S + P
Sbjct: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWS-----SSRGPY 1980
Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629
S + +S+ Q + Y Q + GS AS S G +
Sbjct: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-ASGQSSSCGQHGASSGQS 2039
Query: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ--SNPAQSPFSPHTSP 687
S S SG G+ SPG G S Q + + S S +
Sbjct: 2040 SSHGQHGSGSSQSSGY---GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQ 2096
Query: 688 HLPGIR-----GPSPSPVGSPASVAQ--SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740
H PG+ G S G +S +Q S SG S G++ SGQS
Sbjct: 2097 HGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR------SGQSS---RGE 2147
Query: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG 800
+ SS Y Q Q S + S PS G+ G GS +S G +G
Sbjct: 2148 RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR--HGSGSGHSSSHGQHGSGS 2205
Query: 801 GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG----------GQMHGQPGIPPY 850
G+ +G Y + ++++ + +G + + G+G G GQ
Sbjct: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
Query: 851 GTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
G+ S S G G + ++ Q GSG P
Sbjct: 2266 EGSSTGQSS--SHGQHGSGSSQSSSYGQQGSGSGQSP 2300
Score = 61.2 bits (147), Expect = 1e-08
Identities = 152/705 (21%), Positives = 223/705 (31%), Gaps = 79/705 (11%)
Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393
S +G + + ++ G S +P G GQ + S G + +
Sbjct: 176 SSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHK 235
Query: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453
G + Q G SG G+G G G + + G + S S ++Q
Sbjct: 236 SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295
Query: 454 YGQQG------------------PSGYGQQGQTPYYNQQSPHPQQ---------QQPPYS 486
+G+QG S +GQ G Y+ H + Q S
Sbjct: 296 HGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS 355
Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546
Q + H S Q Q S Q S Q Q S Q + +H
Sbjct: 356 GQSSGYSKHGSGSGHSSSQGQHGS-TSGQASSSGQHGSSSRQSSSY---GQHESASRHSS 411
Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS----QQTAYSQQRFPPPQE 602
+ +S QSP Q+ S S Q +S S + YS F +
Sbjct: 412 GRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS-SGFGHHES 470
Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGALSPGV 661
S+ S G + S SS GQ SR +GS G+ S G
Sbjct: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH 530
Query: 662 STSGISSSQG--------EQSNPAQSPFSPH-TSPHLPGIRGPSPSPVGSPASVA--QSR 710
S G S Q E + S + PH RGP S G + + +SR
Sbjct: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
Query: 711 SGPLSPAAVPGNQM-------PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS 763
SG S G+ SGQS S + + + Q +Y
Sbjct: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650
Query: 764 SPQPGSALSPRQPSGGQIHTGMGSYQQNSMG-----SYGPQG---GQ---YGPQGGYPRQ 812
GS SP + G SY Q+ G S GP G GQ +G + G +
Sbjct: 651 QQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710
Query: 813 PNYNALPNANYPSAGMA--GGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGP 870
Y+ + + S+G G + + + HG G SH S G+ G
Sbjct: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS 770
Query: 871 NMANMPPQV----GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926
+ P +V SG G T ++ H + S Q G G+
Sbjct: 771 GSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHE------SGS 824
Query: 927 GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971
G Y Q S +G + QG S G +++ ++S + G
Sbjct: 825 GQGYSQH-GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
Score = 32.0 bits (71), Expect = 6.4
Identities = 53/244 (21%), Positives = 81/244 (33%), Gaps = 9/244 (3%)
Query: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSD 1196
GSGS Q P Q S S + + + S PG+ S+ G ++ + S
Sbjct: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118
Query: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNG-G 1255
S Q + + GY + S R + S GS SSG G G G
Sbjct: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178
Query: 1256 MGDPYSRAA-GPGLGNVAMGPRQHYPYG-----GPYDRVRTEPGIGPEGNMSTGAPQPNL 1309
G SR G G G+ + + G GPY+ + G +G+ +
Sbjct: 2179 SGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV--FGQHESGSGHSSA 2236
Query: 1310 MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVS 1369
+ + S+ Q D G+ + S Q++ Y QQ S
Sbjct: 2237 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 2296
Query: 1370 SPAP 1373
+P
Sbjct: 2297 GQSP 2300
Score = 31.6 bits (70), Expect = 8.4
Identities = 53/244 (21%), Positives = 81/244 (33%), Gaps = 9/244 (3%)
Query: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSD 1196
GSGS Q P Q S S + + + S G+ S+ G ++ + S
Sbjct: 1589 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648
Query: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNG-G 1255
S Q + + GY + S R + S GS SSG G G G
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708
Query: 1256 MGDPYSRAA-GPGLGNVAMGPRQHYPYG-----GPYDRVRTEPGIGPEGNMSTGAPQPNL 1309
G SR G GLG+ + + G GPY+ + G +G+ +
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV--FGQHESGSGHSSA 1766
Query: 1310 MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVS 1369
+ + S+ Q D G+ + S Q++ Y QQ S
Sbjct: 1767 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 1826
Query: 1370 SPAP 1373
+P
Sbjct: 1827 GQSP 1830
Score = 31.6 bits (70), Expect = 8.4
Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 15/147 (10%)
Query: 77 AESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPP 136
A S G G G S G G+ ++ G +++ G G GSS G
Sbjct: 2706 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY----GHRGSGSSQSSGYGR 2761
Query: 137 HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYA 196
H A + G +GR S +++ + QHG Q G G G + Y+
Sbjct: 2762 HGAGS-------GQSLSHGRHGSGSGQSSS---YGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
Query: 197 GPQQNS-HDHGFPNHQYNSYYPNRSAY 222
+ S HD G + S+ + S Y
Sbjct: 2812 YCKGGSNHDGGSSGSYFLSFPSSTSPY 2838
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 107 bits (266), Expect = 2e-22
Identities = 130/470 (27%), Positives = 175/470 (37%), Gaps = 74/470 (15%)
Query: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375
+GGP G AG G M + G + + A G S P PG+SG +A
Sbjct: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143
Query: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430
TPQ + Q+ + Q + QQQ QQ Q Q+ Q++
Sbjct: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200
Query: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
+Q + Q I + Q QQ Q Q QQQQ QQ
Sbjct: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260
Query: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Q AQP QQ P QP P + P QQ H Q P P P Q Q P P
Sbjct: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319
Query: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597
P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q
Sbjct: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
Query: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL 657
P ++SQ SS P ++S GQ+ P S+P + +
Sbjct: 380 APGVQVSQ-------SSLPMLSSPSPGQQ------VQTPQSMPP----------PPQPSP 416
Query: 658 SPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPV--GSPASVAQSRSGPLS 715
PG +S +S+ P+ S F P SP PS SPV +P + + GPL+
Sbjct: 417 QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ------PSQSPVTARTPQNFSVPSPGPLN 470
Query: 716 PAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765
P + M P SS A+++ Y+ + Q+ +Y P
Sbjct: 471 TPVNPSSVMSPA---------------GSSQAEEQQYLDKLKQLSKYIEP 505
Score = 62.4 bits (150), Expect = 4e-09
Identities = 105/423 (24%), Positives = 139/423 (32%), Gaps = 99/423 (23%)
Query: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
P ++ G + G+ + P G G GQ + Q P P+S
Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140
Query: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q
Sbjct: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197
Query: 543 QHPQSQPPYSQPQAQSPYQQQQP-------------------QQPAPSTLSQQAAYPQPQ 583
Q Q+ Q Q Q QQQQ Q+ A L QQ Q Q
Sbjct: 198 QQFQAVVQQQQ-QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
Query: 584 SQQSQQTAYS---------QQRFPP-----PQELSQDSFGSQ------------ASSAPS 617
QQ QQ + QQ PP PQ+L Q A + PS
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
Query: 618 MTSSKGGQEDMNLSLQSRPSSL------------------PDLSGSIDDLPMGTEGA--- 656
+ + + Q+ P + P + + + A
Sbjct: 317 QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAA 376
Query: 657 --LSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPL 714
++PGV S S +P Q +P + P P PSP P G P+S S
Sbjct: 377 QMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP---QPSPQP-GQPSSQPNSNVSS- 431
Query: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPR 774
PA P + +P PS P +QS + R PQ +S P PG +P
Sbjct: 432 GPAPSPSSFLP--SPS--------PQPSQSPVT------ARTPQ--NFSVPSPGPLNTPV 473
Query: 775 QPS 777
PS
Sbjct: 474 NPS 476
Score = 38.5 bits (88), Expect = 0.069
Identities = 53/206 (25%), Positives = 75/206 (36%), Gaps = 46/206 (22%)
Query: 1325 PPQQQQQQQQRHD----------SYGNQFSTQGTPS-GSPFPSQQTTMYQQQQQVSSPAP 1373
PP Q Q QQQ+ + G Q S P SP P QQ Q P+P
Sbjct: 357 PPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP 416
Query: 1374 LP-----RPMENRTS---PSKSPFLHSGMKMQKAGP-----PVPASHIAPAPVQPPMIRR 1420
P +P N +S PS S FL S P P S +P P+ P+
Sbjct: 417 QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPS 476
Query: 1421 DITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYD 1480
+ P GS +A + + + K I E R M++ D
Sbjct: 477 SVMSPAGSSQAEEQQYLDKLKQLSKYI---EPLRRMINK-------------------ID 514
Query: 1481 DNSIMTFNLSQLPGLLELLVEYFRRC 1506
N +LS++ LL++L + +RC
Sbjct: 515 KNEDRKKDLSKMKSLLDILTDPSKRC 540
Score = 36.2 bits (82), Expect = 0.34
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQV-----SSPAPLPR----- 1376
QQQQQQQQ+ + Q Q P P P + QQ QQ+ P P P+
Sbjct: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA 311
Query: 1377 -------PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSV 1429
P +++T P S +M PP+ AP VQ P ++ + +V
Sbjct: 312 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR-APMVVQQPPVQPQVQQQQTAV 370
Query: 1430 EATQ 1433
+ Q
Sbjct: 371 QTAQ 374
Score = 35.8 bits (81), Expect = 0.45
Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 25/125 (20%)
Query: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308
G G G MG P S + P G M P +ST PQ
Sbjct: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSM-------------------AVVSTATPQTQ 152
Query: 1309 L------MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMY 1362
L + + + QQQQQQQ+ + Q S + QQ
Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ 212
Query: 1363 QQQQQ 1367
QQQQQ
Sbjct: 213 QQQQQ 217
Score = 35.8 bits (81), Expect = 0.45
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 21/121 (17%)
Query: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSK 1386
Q QQQQQQ Q Q QQ QQQQ + + P+ +P + P
Sbjct: 230 QIQQQQQQLQRIAQLQLQQQQ-------QQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 1387 SPFLHSGMKM----QKAGPPVPASHIAPAPVQPPMIRRDIT-FPPGSVEATQPVLKQRRR 1441
S L ++ Q PP P P QPP+ + + PP S TQP++ Q +
Sbjct: 283 SQALPQQLQQMHHTQHHQPP-------PQPQQPPVAQNQPSQLPPQS--QTQPLVSQAQA 333
Query: 1442 L 1442
L
Sbjct: 334 L 334
Score = 32.0 bits (71), Expect = 6.4
Identities = 36/143 (25%), Positives = 52/143 (36%), Gaps = 10/143 (6%)
Query: 1230 KDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR 1289
+D + +A SDP M++ Q GG A G+G GP Q G +
Sbjct: 67 RDIHNKKSQASVSDP-MNALQSLTGGPA-----AGAAGIGMPPRGPGQSLGGMGSLGAMG 120
Query: 1290 TEPGIGPEGNMSTGAPQPNLMP----SNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345
+ + T P+ M + P + + QQQQQQQ +
Sbjct: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
Query: 1346 QGTPSGSPFPSQQTTMYQQQQQV 1368
Q F +QQ+ M QQ Q V
Sbjct: 181 QQQQQQQQFQAQQSAMQQQFQAV 203
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 106 bits (264), Expect = 3e-22
Identities = 236/1002 (23%), Positives = 321/1002 (32%), Gaps = 140/1002 (13%)
Query: 54 AGQESEGPAVGPPQPLGKELQDGAESNGGGGG--------GGAGSGGGPGAEPDLKNSNG 105
AG+ + GPP P G G G G G G G PG + + +
Sbjct: 257 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 316
Query: 106 NAGPRPALNNNL------TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQP-YGRSP 158
N P P L T P G G +DG P A P P G P + +P
Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP-----AGPPGPVGPAGGPGFPGAP 371
Query: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPN 218
A A G Q G + G G P AG N G P + ++ P
Sbjct: 372 GAKGEAGPTGARGPEGAQGPRG----EPGTPGSPGP-AGASGNPGTDGIPGAKGSAGAPG 426
Query: 219 RSAYP-------PPAPAYALS--SPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQ 269
+ P PP P A P+G T G A G + P A
Sbjct: 427 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ------- 479
Query: 270 RFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGP 329
GA G G G +P + A G +G+PG D GP+ +GP
Sbjct: 480 --GAPGPAGEEGKRGARGEPGGVGPIGP--PGERGAPGNRGFPGQDGLAGPKGAPGERGP 535
Query: 330 ADMASQCWG-------AAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381
+ +A A +G + P G+ G G+P P P
Sbjct: 536 SGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP--GPPGPQ 593
Query: 382 SPMDQMGKMR-PQPYG--GTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTPQRYPMTMQG 436
Q G M P P G G + ++G P P G PG+ G+ P
Sbjct: 594 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL-RGLPGKDGETGAAGPPGPAGPAGE 652
Query: 437 RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496
R + G S Q +P G GP G G + ++ P P + P +
Sbjct: 653 RGEQGAPGPSGFQGLP--GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 710
Query: 497 QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA 556
Q P+ P + P + P+ PP Q P + P +
Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 770
Query: 557 QSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQ-------TAYSQQRFPPPQELSQDSFG 609
+ P + L+ P P ++ A S P E +
Sbjct: 771 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830
Query: 610 SQASSA--PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667
A A P G + + + Q + P G P G G P +G
Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-----PSGAPGPQGP-TGVTGPK 884
Query: 668 SSQGEQSNPAQSPF-------SPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAV 719
++G Q P + F P S PG GP P P G A+ SGP A
Sbjct: 885 GARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-PGPSGKDGPKGARGDSGPPGRAGE 943
Query: 720 PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGG 779
PG Q P PP + + P + S A+ P PQ + Q G P Q G
Sbjct: 944 PGLQGPAGPPGEKGE----PGDDGPSGAE-------GPPGPQGLAGQRGIVGLPGQ-RGE 991
Query: 780 QIHTGMGSY-----QQNSMGSYGPQG--GQYGPQG--GYPRQPNYNALPNANYP-----S 825
+ G+ +Q + G+ G +G G GP G G +P P A+ P +
Sbjct: 992 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051
Query: 826 AGMAGGINPMGAGGQMHGQPGIP--PYGTLPPGRMSHASMGNR--PYGPNMANMPPQVGS 881
AG+ G GA G G PG P P P G+ P GP+ P
Sbjct: 1052 AGVKGDRGETGAVGAP-GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS----GPAGAR 1106
Query: 882 GMCPPPGGMNRKTQ-----ETAVAMHVAANSIQNRP-PGYPNMNQGGMMGTGP------- 928
G+ P G K + E + H +Q P P P+ +QG GP
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166
Query: 929 ----PYGQ-GINSMAGMINPQGPPYSMGGTMANNSAGMAASP 965
P G+ G N + G I P GP G T G P
Sbjct: 1167 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208
Score = 102 bits (253), Expect = 5e-21
Identities = 210/834 (25%), Positives = 269/834 (32%), Gaps = 156/834 (18%)
Query: 26 KAEQQQREE---AGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKEL------QDG 76
K EQ + E AG + A A E G+ A GP +GPP G QDG
Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDG 522
Query: 77 AESNGGGGG--------GGAGSGGGPG--AEPDLKNSNGNAG-PRPALNNNLTEPPGGGG 125
G G G G+ G PG EP L + G G P A P G G
Sbjct: 523 LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 582
Query: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL- 184
DG PP A P GF P G + A + G +PGL L
Sbjct: 583 ---EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG-------EKGLPGAPGLRGLP 632
Query: 185 ----QSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
++G G P AGP + G P P PP P G PG
Sbjct: 633 GKDGETGAAGPPGP-AGPAGERGEQGAPGPSGFQGLPG----PPGPPGEGGKPGDQGVPG 687
Query: 241 S----GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPT 294
G G + P S + + G G GP A G G P P
Sbjct: 688 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 747
Query: 295 LNQL--------LTSPSSARGYQGYPGGDYSGGPQDGGAG-------KGPADMASQCWGA 339
L + + P RG G G + + G +DGG G GPA +
Sbjct: 748 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG-KDGGRGLTGPIGPPGPAGANGEKGEV 806
Query: 340 AAAAAAAAAASGGAQ-QRSHHAPMSP----GSSGGGGQPLARTPQ-PSSPMDQMGKMRPQ 393
A +A + GA +R P P G G GQP A+ Q + G PQ
Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866
Query: 394 -PYGGTNPYSQQQGPP--SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ 450
P G P QGP +GP+ G G P + P A +G
Sbjct: 867 GPSGAPGP----QGPTGVTGPKGARGAQGPPGATGFPG---------AAGRVGPPGSNGN 913
Query: 451 IPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510
P G GPSG + G P P + +P Q P P + +P P
Sbjct: 914 PGPPGPPGPSG--KDGPKGARGDSGP------PGRAGEPGLQGPAGPPGEKGEPGDDGPS 965
Query: 511 LQSSQPPYSQQ----------PSQPPHQQSPA-PYPSQQSTTQQHPQSQ----------P 549
+ PP Q P Q + P P PS + Q P + P
Sbjct: 966 -GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 1024
Query: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609
P A P ++ P P A + + + A P P G
Sbjct: 1025 PGLTGPAGEPGREGSPGADGPPGRDGAAGV---KGDRGETGAVGAPGAPGPP-------G 1074
Query: 610 SQASSAPSMTSSKGGQEDMNLSL-QSRPSSLPDLSGSIDDLPMGTEG-ALSPGV----ST 663
S + P+ G+ + S P+ + G P G +G A PG
Sbjct: 1075 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG--PRGDKGEAGEPGERGLKGH 1132
Query: 664 SGISSSQGEQSNP-------AQSPFSPHTSPHLPGIRGPS--------PSPVGSPASVAQ 708
G + QG P A P P PG GPS P P+G P +
Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP--R 1190
Query: 709 SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762
RSG PA PGN PP PP P ++ S+ A G ++ P QY
Sbjct: 1191 GRSGETGPAGPPGNPGPPGPPGPPG-----PGIDMSAFA-GLGPREKGPDPLQY 1238
Score = 101 bits (252), Expect = 7e-21
Identities = 243/1002 (24%), Positives = 316/1002 (31%), Gaps = 229/1002 (22%)
Query: 14 GNPPPP----PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPL 69
GNP PP PP + AGG A A+ G M+ G GP GPP P
Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM--GPR-GPPGP- 214
Query: 70 GKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129
G G G G PG EP +G GPR PPG G
Sbjct: 215 ------------AGAPGPQGFQGNPG-EPGEPGVSGPMGPRG--------PPGPPGKPGD 253
Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
DG P A PP G G +PGL ++ G
Sbjct: 254 DGEAGKPGKAGERGPPGPQG----------------------ARGFPGTPGLPGVKGHRG 291
Query: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249
Y G + G P + S P + P P L RG T +GAA A G+
Sbjct: 292 -----YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346
Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
P G G GP GG P A + P+ ARG +
Sbjct: 347 DGQP------------------GPAGPPGPVGPAGGPGFPGAPGAKGE--AGPTGARGPE 386
Query: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369
G G G P G+ GPA + A S GA PG +G
Sbjct: 387 GAQGP--RGEPGTPGS-PGPAGASGN---PGTDGIPGAKGSAGA----------PGIAGA 430
Query: 370 GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTP 427
G P R P P P G T P GP+ G PG G Q P
Sbjct: 431 PGFPGPRGP-------------PGPQGATGPL--------GPKGQTGEPGIAGFKGEQGP 469
Query: 428 QRYPMTMQGRAQSAMGGLSYTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
+ P G + Q P P G++G G +G+ P P ++ P +
Sbjct: 470 KGEP------------GPAGPQGAPGPAGEEGKRG--ARGEPGGVGPIGP-PGERGAPGN 514
Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546
+ P Q A P + P + P + + P +P P + T +
Sbjct: 515 RGFPGQDGLAGP--KGAPGERGPSGLAGPKGANGDPGRP----GEPGLPGARGLTGRPGD 568
Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606
+ P + +P + +P P P Q A QP FP P+
Sbjct: 569 AGPQGKVGPSGAPGEDGRPGPPGP-----QGARGQP----------GVMGFPGPKG---- 609
Query: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM--GTEGALSPGVSTS 664
A+ P KG LP G + LP G GA P +
Sbjct: 610 -----ANGEPGKAGEKG---------------LPGAPG-LRGLPGKDGETGAAGPP-GPA 647
Query: 665 GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAVPGNQ 723
G + +GEQ P S F P P G P G P A GP PG +
Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 707
Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783
P + + P + D P P + PG P + I
Sbjct: 708 GSPG-----AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 762
Query: 784 GMGSYQQNSMGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGINPMG 836
G + +G GP+G G+ G +G G P N P G AG G
Sbjct: 763 PKGD--RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP-GPAGSAGARG 819
Query: 837 AGGQMHGQPGIP-PYGTL-PPG-------RMSHASMGNR-------PYGPNMANMPPQVG 880
A G+ G+ G P P G PPG + G + P GP+ A PQ
Sbjct: 820 APGE-RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP-GPQGP 877
Query: 881 SGMCPPPGGMNRKTQETAVAMHVAANSI-------QNRPPGYPNMN-----QGGMMGTGP 928
+G+ P G + A AA + PPG P + +G +GP
Sbjct: 878 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 937
Query: 929 PYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
P G G+ P GPP G + +G P GL
Sbjct: 938 P---GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976
Score = 84.3 bits (207), Expect = 1e-15
Identities = 144/574 (25%), Positives = 176/574 (30%), Gaps = 67/574 (11%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAER---GEMKAAAGQESEGP-- 61
P+ L PP PP K +Q EAG ER GE + Q +GP
Sbjct: 661 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720
Query: 62 ------------AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGP 109
A GP P G + G + G G AG G G D+ P
Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGM-PGERGAAGIAGPKGDRGDVGEKGPEGAP 779
Query: 110 RPALNNNLT---EPPGGGGGGSSDGVGAPPHSAAAA------------LPPPAYGFGQPY 154
LT PPG G G PP A +A PP GF P
Sbjct: 780 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839
Query: 155 GR--SPSAVAAAAAAVFHQQHG--GQQSPGLAALQSGGGG--GLEPYAGPQQNSHDHGFP 208
G P A A G G Q P A G G G + G Q GFP
Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899
Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ 268
P + P P P G + G A G PP + +
Sbjct: 900 GAAGRVGPPGSNGNPGP------PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 953
Query: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPG-GDYSGGPQDGGAGK 327
G G GPS A G P P ++ P RG +G+PG SG P GA
Sbjct: 954 GEKGEPGDDGPSGA-EGPPGPQGLAGQRGIVGLPGQ-RGERGFPGLPGPSGEPGKQGAPG 1011
Query: 328 GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR-------TPQP 380
D G A ++ S A PG G G R P
Sbjct: 1012 ASGDRGPP--GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1069
Query: 381 SSPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
P G P G + QGP PSGP G G P G + + R
Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG-PQGPRGDKGEAGEPGERG 1128
Query: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPH-PQQQQPPYSQQPPSQTPHAQ 497
G + Q +P G GPS G QG + P P P + + P
Sbjct: 1129 LKGHRGFTGLQGLP--GPPGPS--GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP--G 1182
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531
P P+ + + + PP + P PP P
Sbjct: 1183 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216
Score = 83.6 bits (205), Expect = 2e-15
Identities = 138/495 (27%), Positives = 158/495 (31%), Gaps = 117/495 (23%)
Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75
PP P + +K E AG A A ERGE GPP P G
Sbjct: 793 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE-------------TGPPGPAGFAGPP 839
Query: 76 GAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133
GA+ G G G AG G GA P + +G GP+ +T P G G G
Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGAT 896
Query: 134 APPHSAAAALPPPAYGF-GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192
P +A PP + G G P PS A G PG A G GL
Sbjct: 897 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-----RGDSGPPGRA-----GEPGL 946
Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAAGSK 250
+ AGP + G A PP P L+ RG G PG
Sbjct: 947 QGPAGPPGEKGEPGDDGPS--------GAEGPPGP-QGLAGQRGIVGLPGQRGERGFPGL 997
Query: 251 PPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTLNQLLTSPSSARGYQ 309
P PS G P A+G G P P P LT P+ G +
Sbjct: 998 PGPSGEPGKQ----------------GAPGASGDRGPPGPVGPPG----LTGPAGEPGRE 1037
Query: 310 GYPGGDYSGGPQDGGAG----------------------KGPA-DMASQCWGAAAAAAAA 346
G PG D G +DG AG GPA Q A A
Sbjct: 1038 GSPGADGPPG-RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096
Query: 347 AAASGGAQQRSHHAPMSP-GSSGGGGQP-------------LARTPQPSSPMDQMGKMRP 392
SG A R P P G G G+P L P P P G P
Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156
Query: 393 Q-PYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ 449
P G P GP PSG +G PG P G P R +S G +
Sbjct: 1157 AGPSGPRGP----PGPVGPSGKDGANGIPG-PIGPPGP---------RGRSGETGPAGPP 1202
Query: 450 QIP-PYGQQGPSGYG 463
P P G GP G G
Sbjct: 1203 GNPGPPGPPGPPGPG 1217
Score = 64.3 bits (155), Expect = 1e-09
Identities = 155/667 (23%), Positives = 206/667 (30%), Gaps = 93/667 (13%)
Query: 364 PGSSGGGGQP--LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP 421
PG G G+P + P P G Q G ++G P GP+ G PG P
Sbjct: 100 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP-GPRGRDGEPGTP 158
Query: 422 YGSQTPQ------------RYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTP 469
P + M G GG P G GP G P
Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 218
Query: 470 YYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQ 529
P Q P +P P P P +P + P PP Q
Sbjct: 219 -----GPQGFQGNPGEPGEPGVSGPMG-PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272
Query: 530 SPAPYPSQQSTT-----QQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
+P + +P ++ P + ++ SP + P P L +
Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332
Query: 578 AYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPS 637
P + Q P + G AP G P
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392
Query: 638 SLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP 697
P GS P G G +PG T GI ++G P + +P PG RGP P
Sbjct: 393 GEPGTPGSPG--PAGASG--NPG--TDGIPGAKGSAGAPGIAG-----APGFPGPRGP-P 440
Query: 698 SPVGSPASVA-QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRN 756
P G+ + + ++G A G Q P P + RG
Sbjct: 441 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG----- 495
Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG------- 807
+PG + P P G + G + G GP+G G+ GP G
Sbjct: 496 ---------EPGG-VGPIGPPGERGAPGNRGFPGQD-GLAGPKGAPGERGPSGLAGPKGA 544
Query: 808 -GYPRQPNYNALPNANYPS-----AGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHA 861
G P +P LP A + AG G + P GA G+ G+PG P P G
Sbjct: 545 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE-DGRPGPPG----PQGARGQP 599
Query: 862 SMGNRPYGPNMANMPPQVGS--GMCPPPG--GMNRKTQETAVA-----MHVAANSIQNRP 912
+ P GP AN P G+ PG G+ K ET A A +
Sbjct: 600 GVMGFP-GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658
Query: 913 PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972
PG P+ QG GPP G G+ G P +G G SP GL
Sbjct: 659 PG-PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 717
Query: 973 VKLTPAT 979
+ P T
Sbjct: 718 PRGLPGT 724
Score = 64.3 bits (155), Expect = 1e-09
Identities = 88/351 (25%), Positives = 113/351 (32%), Gaps = 43/351 (12%)
Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG-----GEAAAAAAAERGEMKAAAGQ 56
A +V P ++ PP PP K + R ++G GE A K G
Sbjct: 902 AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 961
Query: 57 ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG-GGPGAEPDLKNSNGNAG----PRP 111
+ A GPP P G Q G G G G GP EP + + G +G P P
Sbjct: 962 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021
Query: 112 ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYG----FGQPYGRSPSAVAAAAAA 167
LT P G G S G PP AA G G P P A
Sbjct: 1022 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081
Query: 168 VFHQ---QHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQ----YNSYYPNRS 220
Q G Q P + G G++ GP+ + + G P + + + +
Sbjct: 1082 TGKQGDRGEAGAQGP-MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1140
Query: 221 AYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPS 280
PP P+ G SG A +G + PP S A G +G GP
Sbjct: 1141 LPGPPGPS-------GDQGASGPAGPSGPRGPP---GPVGPSGKDGANGIPGPIGPPGPR 1190
Query: 281 AAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPAD 331
G T P G G PG G AG GP +
Sbjct: 1191 GRSGETGP-----------AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPRE 1230
Score = 49.7 bits (117), Expect = 3e-05
Identities = 91/359 (25%), Positives = 113/359 (31%), Gaps = 38/359 (10%)
Query: 648 DLPMGTEGALSPG--VSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGPSPSPV 700
++P G + P + SG +G++ P P P G +GP
Sbjct: 79 EIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRG 138
Query: 701 GSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMP 760
A G PGN PP PP P + + AQ G
Sbjct: 139 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP----PGLGGNFAAQMAGGFDEKAGGA 194
Query: 761 QYSSPQ-PGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG--GYPRQPNY 815
Q Q P + PR P G G +Q N G G G G GP+G G P +P
Sbjct: 195 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNP-GEPGEPGVSGPMGPRGPPGPPGKPGD 253
Query: 816 NALPNANYPS-AGMAGGINPMGAGGQMHGQPGIPPYGTLP--PGRMSHASMGNRPYGPNM 872
+ A P AG G P GA G G PG+P PG P
Sbjct: 254 DG--EAGKPGKAGERGPPGPQGARG-FPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE 310
Query: 873 ANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA--NSIQNRPPGYPNMNQGGMMGTGPPY 930
+ P + GS P G+ + T A A N Q P G P GP
Sbjct: 311 SGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP-------VGPAG 363
Query: 931 GQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP 989
G G G GP + G A G +P G P T DG P
Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGT------DGIP 416
Score = 34.7 bits (78), Expect = 0.99
Identities = 51/202 (25%), Positives = 65/202 (32%), Gaps = 32/202 (15%)
Query: 1108 ERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAS 1167
E+GE PP +A ++ + + P G GP + E G+ A
Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861
Query: 1168 TPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYE 1227
P Q P S + G Q G R + P PG + +G
Sbjct: 862 APGPQGP-------SGAPGPQGP--TGVTGPKGARGAQGP-PGATGFPGAAGRVGPPGSN 911
Query: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD--PYSRAAGPGLGNVAMGPRQHYPYGGPY 1285
N P G P S GP G GD P RA PGL A P +
Sbjct: 912 GNPGPPG--------PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-------- 955
Query: 1286 DRVRTEPG-IGPEGNMSTGAPQ 1306
+ EPG GP G PQ
Sbjct: 956 ---KGEPGDDGPSGAEGPPGPQ 974
Score = 32.7 bits (73), Expect = 3.8
Identities = 46/172 (26%), Positives = 59/172 (34%), Gaps = 32/172 (18%)
Query: 1126 SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGD--LK-------------PPTPASTPH 1170
+Q + P PAG+ +QGPQ P+ E G+ LK PP P+
Sbjct: 1093 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQG 1152
Query: 1171 SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNP-GYQPSMNTSDMMGRMSYEPN 1229
+ P P R + + DG++ P P G S G N
Sbjct: 1153 ASGPAGPSGPRGPPGPVGPSGKDGANG--------IPGPIGPPGPRGRSGETGPAGPPGN 1204
Query: 1230 KDPYGSM-RKAPGSDPFMSSGQGPNGGMGDP--YSRAAGPGLGNVAMGPRQH 1278
P G PG D +G GP DP Y RA A G RQH
Sbjct: 1205 PGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRA-----DQAAGGLRQH 1251
Score = 31.6 bits (70), Expect = 8.4
Identities = 38/153 (24%), Positives = 51/153 (33%), Gaps = 16/153 (10%)
Query: 1109 RGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAST 1168
RG PP A + ++ PP G+ GP P GD PP A
Sbjct: 887 RGAQGPP---GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943
Query: 1169 PHSQIPPLPGMSRS--NSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSY 1226
P Q P P + G A + + PG + + G S
Sbjct: 944 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSG 1002
Query: 1227 EPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDP 1259
EP K + APG+ S +GP G +G P
Sbjct: 1003 EPGK------QGAPGA----SGDRGPPGPVGPP 1025
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 106 bits (264), Expect = 3e-22
Identities = 231/985 (23%), Positives = 319/985 (32%), Gaps = 138/985 (14%)
Query: 54 AGQESEGPAVGPPQPLGKELQDGAESNGGGGG--------GGAGSGGGPGAEPDLKNSNG 105
AG+ + GPP P G G G G G G G PG + + +
Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 247
Query: 106 NAGPRPALNNNL------TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQP-YGRSP 158
N P P L T P G G +DG P A P P G P + +P
Sbjct: 248 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP-----AGPPGPVGPAGGPGFPGAP 302
Query: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPN 218
A A G Q G + G G P AG N G P + ++ P
Sbjct: 303 GAKGEAGPTGARGPEGAQGPRG----EPGTPGSPGP-AGASGNPGTDGIPGAKGSAGAPG 357
Query: 219 RSAYP-------PPAPAYALS--SPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQ 269
+ P PP P A P+G T G A G + P A
Sbjct: 358 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ------- 410
Query: 270 RFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGP 329
GA G G G +P + A G +G+PG D GP+ +GP
Sbjct: 411 --GAPGPAGEEGKRGARGEPGGVGPIGP--PGERGAPGNRGFPGQDGLAGPKGAPGERGP 466
Query: 330 ADMASQCWG-------AAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381
+ +A A +G + P G+ G G+P P P
Sbjct: 467 SGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP--GPPGPQ 524
Query: 382 SPMDQMGKMR-PQPYG--GTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTPQRYPMTMQG 436
Q G M P P G G + ++G P P G PG+ G+ P
Sbjct: 525 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL-RGLPGKDGETGAAGPPGPAGPAGE 583
Query: 437 RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496
R + G S Q +P G GP G G + ++ P P + P +
Sbjct: 584 RGEQGAPGPSGFQGLP--GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 641
Query: 497 QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA 556
Q P+ P + P + P+ PP Q P + P +
Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 701
Query: 557 QSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQ-------TAYSQQRFPPPQELSQDSFG 609
+ P + L+ P P ++ A S P E +
Sbjct: 702 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761
Query: 610 SQASSA--PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667
A A P G + + + Q + P G P G G P +G
Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-----PSGAPGPQGP-TGVTGPK 815
Query: 668 SSQGEQSNPAQSPF-------SPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAV 719
++G Q P + F P S PG GP P P G A+ SGP A
Sbjct: 816 GARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-PGPSGKDGPKGARGDSGPPGRAGE 874
Query: 720 PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGG 779
PG Q P PP + + P + S A+ P PQ + Q G P Q G
Sbjct: 875 PGLQGPAGPPGEKGE----PGDDGPSGAE-------GPPGPQGLAGQRGIVGLPGQ-RGE 922
Query: 780 QIHTGMGSY-----QQNSMGSYGPQG--GQYGPQG--GYPRQPNYNALPNANYP-----S 825
+ G+ +Q + G+ G +G G GP G G +P P A+ P +
Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982
Query: 826 AGMAGGINPMGAGGQMHGQPGIP--PYGTLPPGRMSHASMGNR--PYGPNMANMPPQVGS 881
AG+ G GA G G PG P P P G+ P GP+ P
Sbjct: 983 AGVKGDRGETGAVGAP-GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS----GPAGAR 1037
Query: 882 GMCPPPGGMNRKTQ-----ETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINS 936
G+ P G K + E + H +Q P G P GP QG +
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP-GPP----------GPSGDQGASG 1086
Query: 937 MAGMINPQGPPYSMGGTMANNSAGM 961
AG P+GPP +G + + + G+
Sbjct: 1087 PAGPSGPRGPPGPVGPSGKDGANGI 1111
Score = 102 bits (253), Expect = 5e-21
Identities = 210/834 (25%), Positives = 269/834 (32%), Gaps = 156/834 (18%)
Query: 26 KAEQQQREE---AGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKEL------QDG 76
K EQ + E AG + A A E G+ A GP +GPP G QDG
Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDG 453
Query: 77 AESNGGGGG--------GGAGSGGGPG--AEPDLKNSNGNAG-PRPALNNNLTEPPGGGG 125
G G G G+ G PG EP L + G G P A P G G
Sbjct: 454 LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 513
Query: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL- 184
DG PP A P GF P G + A + G +PGL L
Sbjct: 514 ---EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG-------EKGLPGAPGLRGLP 563
Query: 185 ----QSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
++G G P AGP + G P P PP P G PG
Sbjct: 564 GKDGETGAAGPPGP-AGPAGERGEQGAPGPSGFQGLPG----PPGPPGEGGKPGDQGVPG 618
Query: 241 S----GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPT 294
G G + P S + + G G GP A G G P P
Sbjct: 619 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678
Query: 295 LNQL--------LTSPSSARGYQGYPGGDYSGGPQDGGAG-------KGPADMASQCWGA 339
L + + P RG G G + + G +DGG G GPA +
Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG-KDGGRGLTGPIGPPGPAGANGEKGEV 737
Query: 340 AAAAAAAAAASGGAQ-QRSHHAPMSP----GSSGGGGQPLARTPQ-PSSPMDQMGKMRPQ 393
A +A + GA +R P P G G GQP A+ Q + G PQ
Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797
Query: 394 -PYGGTNPYSQQQGPP--SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ 450
P G P QGP +GP+ G G P + P A +G
Sbjct: 798 GPSGAPGP----QGPTGVTGPKGARGAQGPPGATGFPG---------AAGRVGPPGSNGN 844
Query: 451 IPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510
P G GPSG + G P P + +P Q P P + +P P
Sbjct: 845 PGPPGPPGPSG--KDGPKGARGDSGP------PGRAGEPGLQGPAGPPGEKGEPGDDGPS 896
Query: 511 LQSSQPPYSQQ----------PSQPPHQQSPA-PYPSQQSTTQQHPQSQ----------P 549
+ PP Q P Q + P P PS + Q P + P
Sbjct: 897 -GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 955
Query: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609
P A P ++ P P A + + + A P P G
Sbjct: 956 PGLTGPAGEPGREGSPGADGPPGRDGAAGV---KGDRGETGAVGAPGAPGPP-------G 1005
Query: 610 SQASSAPSMTSSKGGQEDMNLSL-QSRPSSLPDLSGSIDDLPMGTEG-ALSPGV----ST 663
S + P+ G+ + S P+ + G P G +G A PG
Sbjct: 1006 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG--PRGDKGEAGEPGERGLKGH 1063
Query: 664 SGISSSQGEQSNP-------AQSPFSPHTSPHLPGIRGPS--------PSPVGSPASVAQ 708
G + QG P A P P PG GPS P P+G P +
Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP--R 1121
Query: 709 SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762
RSG PA PGN PP PP P ++ S+ A G ++ P QY
Sbjct: 1122 GRSGETGPAGPPGNPGPPGPPGPPG-----PGIDMSAFA-GLGPREKGPDPLQY 1169
Score = 101 bits (252), Expect = 7e-21
Identities = 243/1002 (24%), Positives = 316/1002 (31%), Gaps = 229/1002 (22%)
Query: 14 GNPPPP----PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPL 69
GNP PP PP + AGG A A+ G M+ G GP GPP P
Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM--GPR-GPPGP- 145
Query: 70 GKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129
G G G G PG EP +G GPR PPG G
Sbjct: 146 ------------AGAPGPQGFQGNPG-EPGEPGVSGPMGPRG--------PPGPPGKPGD 184
Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
DG P A PP G G +PGL ++ G
Sbjct: 185 DGEAGKPGKAGERGPPGPQG----------------------ARGFPGTPGLPGVKGHRG 222
Query: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249
Y G + G P + S P + P P L RG T +GAA A G+
Sbjct: 223 -----YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277
Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
P G G GP GG P A + P+ ARG +
Sbjct: 278 DGQP------------------GPAGPPGPVGPAGGPGFPGAPGAKGE--AGPTGARGPE 317
Query: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369
G G G P G+ GPA + A S GA PG +G
Sbjct: 318 GAQGP--RGEPGTPGS-PGPAGASGN---PGTDGIPGAKGSAGA----------PGIAGA 361
Query: 370 GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTP 427
G P R P P P G T P GP+ G PG G Q P
Sbjct: 362 PGFPGPRGP-------------PGPQGATGPL--------GPKGQTGEPGIAGFKGEQGP 400
Query: 428 QRYPMTMQGRAQSAMGGLSYTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
+ P G + Q P P G++G G +G+ P P ++ P +
Sbjct: 401 KGEP------------GPAGPQGAPGPAGEEGKRG--ARGEPGGVGPIGP-PGERGAPGN 445
Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546
+ P Q A P + P + P + + P +P P + T +
Sbjct: 446 RGFPGQDGLAGP--KGAPGERGPSGLAGPKGANGDPGRP----GEPGLPGARGLTGRPGD 499
Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606
+ P + +P + +P P P Q A QP FP P+
Sbjct: 500 AGPQGKVGPSGAPGEDGRPGPPGP-----QGARGQP----------GVMGFPGPKG---- 540
Query: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM--GTEGALSPGVSTS 664
A+ P KG LP G + LP G GA P +
Sbjct: 541 -----ANGEPGKAGEKG---------------LPGAPG-LRGLPGKDGETGAAGPP-GPA 578
Query: 665 GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAVPGNQ 723
G + +GEQ P S F P P G P G P A GP PG +
Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 638
Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783
P + + P + D P P + PG P + I
Sbjct: 639 GSPG-----AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 693
Query: 784 GMGSYQQNSMGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGINPMG 836
G + +G GP+G G+ G +G G P N P G AG G
Sbjct: 694 PKGD--RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP-GPAGSAGARG 750
Query: 837 AGGQMHGQPGIP-PYGTL-PPG-------RMSHASMGNR-------PYGPNMANMPPQVG 880
A G+ G+ G P P G PPG + G + P GP+ A PQ
Sbjct: 751 APGE-RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP-GPQGP 808
Query: 881 SGMCPPPGGMNRKTQETAVAMHVAANSI-------QNRPPGYPNMN-----QGGMMGTGP 928
+G+ P G + A AA + PPG P + +G +GP
Sbjct: 809 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 868
Query: 929 PYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
P G G+ P GPP G + +G P GL
Sbjct: 869 P---GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907
Score = 84.3 bits (207), Expect = 1e-15
Identities = 144/574 (25%), Positives = 176/574 (30%), Gaps = 67/574 (11%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAER---GEMKAAAGQESEGP-- 61
P+ L PP PP K +Q EAG ER GE + Q +GP
Sbjct: 592 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651
Query: 62 ------------AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGP 109
A GP P G + G + G G AG G G D+ P
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGM-PGERGAAGIAGPKGDRGDVGEKGPEGAP 710
Query: 110 RPALNNNLT---EPPGGGGGGSSDGVGAPPHSAAAA------------LPPPAYGFGQPY 154
LT PPG G G PP A +A PP GF P
Sbjct: 711 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770
Query: 155 GR--SPSAVAAAAAAVFHQQHG--GQQSPGLAALQSGGGG--GLEPYAGPQQNSHDHGFP 208
G P A A G G Q P A G G G + G Q GFP
Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830
Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ 268
P + P P P G + G A G PP + +
Sbjct: 831 GAAGRVGPPGSNGNPGP------PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 884
Query: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPG-GDYSGGPQDGGAGK 327
G G GPS A G P P ++ P RG +G+PG SG P GA
Sbjct: 885 GEKGEPGDDGPSGA-EGPPGPQGLAGQRGIVGLPGQ-RGERGFPGLPGPSGEPGKQGAPG 942
Query: 328 GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR-------TPQP 380
D G A ++ S A PG G G R P
Sbjct: 943 ASGDRGPP--GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1000
Query: 381 SSPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
P G P G + QGP PSGP G G P G + + R
Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG-PQGPRGDKGEAGEPGERG 1059
Query: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPH-PQQQQPPYSQQPPSQTPHAQ 497
G + Q +P G GPS G QG + P P P + + P
Sbjct: 1060 LKGHRGFTGLQGLP--GPPGPS--GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP--G 1113
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531
P P+ + + + PP + P PP P
Sbjct: 1114 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147
Score = 83.6 bits (205), Expect = 2e-15
Identities = 138/495 (27%), Positives = 158/495 (31%), Gaps = 117/495 (23%)
Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75
PP P + +K E AG A A ERGE GPP P G
Sbjct: 724 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE-------------TGPPGPAGFAGPP 770
Query: 76 GAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133
GA+ G G G AG G GA P + +G GP+ +T P G G G
Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGAT 827
Query: 134 APPHSAAAALPPPAYGF-GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192
P +A PP + G G P PS A G PG A G GL
Sbjct: 828 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-----RGDSGPPGRA-----GEPGL 877
Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAAGSK 250
+ AGP + G A PP P L+ RG G PG
Sbjct: 878 QGPAGPPGEKGEPGDDGPS--------GAEGPPGP-QGLAGQRGIVGLPGQRGERGFPGL 928
Query: 251 PPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTLNQLLTSPSSARGYQ 309
P PS G P A+G G P P P LT P+ G +
Sbjct: 929 PGPSGEPGKQ----------------GAPGASGDRGPPGPVGPPG----LTGPAGEPGRE 968
Query: 310 GYPGGDYSGGPQDGGAG----------------------KGPA-DMASQCWGAAAAAAAA 346
G PG D G +DG AG GPA Q A A
Sbjct: 969 GSPGADGPPG-RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027
Query: 347 AAASGGAQQRSHHAPMSP-GSSGGGGQP-------------LARTPQPSSPMDQMGKMRP 392
SG A R P P G G G+P L P P P G P
Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087
Query: 393 Q-PYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ 449
P G P GP PSG +G PG P G P R +S G +
Sbjct: 1088 AGPSGPRGP----PGPVGPSGKDGANGIPG-PIGPPGP---------RGRSGETGPAGPP 1133
Query: 450 QIP-PYGQQGPSGYG 463
P P G GP G G
Sbjct: 1134 GNPGPPGPPGPPGPG 1148
Score = 64.3 bits (155), Expect = 1e-09
Identities = 155/667 (23%), Positives = 206/667 (30%), Gaps = 93/667 (13%)
Query: 364 PGSSGGGGQP--LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP 421
PG G G+P + P P G Q G ++G P GP+ G PG P
Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP-GPRGRDGEPGTP 89
Query: 422 YGSQTPQ------------RYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTP 469
P + M G GG P G GP G P
Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149
Query: 470 YYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQ 529
P Q P +P P P P +P + P PP Q
Sbjct: 150 -----GPQGFQGNPGEPGEPGVSGPMG-PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203
Query: 530 SPAPYPSQQSTT-----QQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
+P + +P ++ P + ++ SP + P P L +
Sbjct: 204 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263
Query: 578 AYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPS 637
P + Q P + G AP G P
Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323
Query: 638 SLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP 697
P GS P G G +PG T GI ++G P + +P PG RGP P
Sbjct: 324 GEPGTPGSPG--PAGASG--NPG--TDGIPGAKGSAGAPGIAG-----APGFPGPRGP-P 371
Query: 698 SPVGSPASVA-QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRN 756
P G+ + + ++G A G Q P P + RG
Sbjct: 372 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG----- 426
Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG------- 807
+PG + P P G + G + G GP+G G+ GP G
Sbjct: 427 ---------EPGG-VGPIGPPGERGAPGNRGFPGQD-GLAGPKGAPGERGPSGLAGPKGA 475
Query: 808 -GYPRQPNYNALPNANYPS-----AGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHA 861
G P +P LP A + AG G + P GA G+ G+PG P P G
Sbjct: 476 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE-DGRPGPPG----PQGARGQP 530
Query: 862 SMGNRPYGPNMANMPPQVGS--GMCPPPG--GMNRKTQETAVA-----MHVAANSIQNRP 912
+ P GP AN P G+ PG G+ K ET A A +
Sbjct: 531 GVMGFP-GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589
Query: 913 PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972
PG P+ QG GPP G G+ G P +G G SP GL
Sbjct: 590 PG-PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 648
Query: 973 VKLTPAT 979
+ P T
Sbjct: 649 PRGLPGT 655
Score = 64.3 bits (155), Expect = 1e-09
Identities = 88/351 (25%), Positives = 113/351 (32%), Gaps = 43/351 (12%)
Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG-----GEAAAAAAAERGEMKAAAGQ 56
A +V P ++ PP PP K + R ++G GE A K G
Sbjct: 833 AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 892
Query: 57 ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG-GGPGAEPDLKNSNGNAG----PRP 111
+ A GPP P G Q G G G G GP EP + + G +G P P
Sbjct: 893 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952
Query: 112 ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYG----FGQPYGRSPSAVAAAAAA 167
LT P G G S G PP AA G G P P A
Sbjct: 953 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012
Query: 168 VFHQ---QHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQ----YNSYYPNRS 220
Q G Q P + G G++ GP+ + + G P + + + +
Sbjct: 1013 TGKQGDRGEAGAQGP-MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1071
Query: 221 AYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPS 280
PP P+ G SG A +G + PP S A G +G GP
Sbjct: 1072 LPGPPGPS-------GDQGASGPAGPSGPRGPP---GPVGPSGKDGANGIPGPIGPPGPR 1121
Query: 281 AAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPAD 331
G T P G G PG G AG GP +
Sbjct: 1122 GRSGETGP-----------AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPRE 1161
Score = 47.4 bits (111), Expect = 1e-04
Identities = 84/316 (26%), Positives = 102/316 (32%), Gaps = 37/316 (11%)
Query: 690 PGIRGPS--PSPVGSPASVAQSRS----GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743
PG +GP+ P G + + G PGN PP PP P +
Sbjct: 53 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP----PGLGG 108
Query: 744 SSIAQDRGYMQRNPQMPQYSSPQ-PGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-- 800
+ AQ G Q Q P + PR P G G +Q N G G G
Sbjct: 109 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNP-GEPGEPGVS 167
Query: 801 GQYGPQG--GYPRQPNYNALPNANYPS-AGMAGGINPMGAGGQMHGQPGIPPYGTLP--P 855
G GP+G G P +P + A P AG G P GA G G PG+P P
Sbjct: 168 GPMGPRGPPGPPGKPGDDG--EAGKPGKAGERGPPGPQGARG-FPGTPGLPGVKGHRGYP 224
Query: 856 GRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA--NSIQNRPP 913
G P + P + GS P G+ + T A A N Q P
Sbjct: 225 GLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 284
Query: 914 GYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973
G P GP G G G GP + G A G +P G
Sbjct: 285 GPPGP-------VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337
Query: 974 KLTPATKMNNKADGTP 989
P T DG P
Sbjct: 338 SGNPGT------DGIP 347
Score = 34.7 bits (78), Expect = 0.99
Identities = 51/202 (25%), Positives = 65/202 (32%), Gaps = 32/202 (15%)
Query: 1108 ERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAS 1167
E+GE PP +A ++ + + P G GP + E G+ A
Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792
Query: 1168 TPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYE 1227
P Q P S + G Q G R + P PG + +G
Sbjct: 793 APGPQGP-------SGAPGPQGP--TGVTGPKGARGAQGP-PGATGFPGAAGRVGPPGSN 842
Query: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD--PYSRAAGPGLGNVAMGPRQHYPYGGPY 1285
N P G P S GP G GD P RA PGL A P +
Sbjct: 843 GNPGPPG--------PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-------- 886
Query: 1286 DRVRTEPG-IGPEGNMSTGAPQ 1306
+ EPG GP G PQ
Sbjct: 887 ---KGEPGDDGPSGAEGPPGPQ 905
Score = 32.7 bits (73), Expect = 3.8
Identities = 46/172 (26%), Positives = 59/172 (34%), Gaps = 32/172 (18%)
Query: 1126 SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGD--LK-------------PPTPASTPH 1170
+Q + P PAG+ +QGPQ P+ E G+ LK PP P+
Sbjct: 1024 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQG 1083
Query: 1171 SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNP-GYQPSMNTSDMMGRMSYEPN 1229
+ P P R + + DG++ P P G S G N
Sbjct: 1084 ASGPAGPSGPRGPPGPVGPSGKDGANG--------IPGPIGPPGPRGRSGETGPAGPPGN 1135
Query: 1230 KDPYGSM-RKAPGSDPFMSSGQGPNGGMGDP--YSRAAGPGLGNVAMGPRQH 1278
P G PG D +G GP DP Y RA A G RQH
Sbjct: 1136 PGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRA-----DQAAGGLRQH 1182
Score = 31.6 bits (70), Expect = 8.4
Identities = 38/153 (24%), Positives = 51/153 (33%), Gaps = 16/153 (10%)
Query: 1109 RGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAST 1168
RG PP A + ++ PP G+ GP P GD PP A
Sbjct: 818 RGAQGPP---GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874
Query: 1169 PHSQIPPLPGMSRS--NSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSY 1226
P Q P P + G A + + PG + + G S
Sbjct: 875 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSG 933
Query: 1227 EPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDP 1259
EP K + APG+ S +GP G +G P
Sbjct: 934 EPGK------QGAPGA----SGDRGPPGPVGPP 956
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 105 bits (261), Expect = 6e-22
Identities = 139/480 (28%), Positives = 182/480 (37%), Gaps = 54/480 (11%)
Query: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375
+GGP G AG G M + G + + A G S P PG+SG +A
Sbjct: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143
Query: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430
TPQ + Q+ + Q + QQQ QQ Q Q+ Q++
Sbjct: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200
Query: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
+Q + Q I + Q QQ Q Q QQQQ QQ
Sbjct: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260
Query: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Q AQP QQ P QP P + P QQ H Q P P P Q Q P P
Sbjct: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319
Query: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597
P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q
Sbjct: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
Query: 598 PP-----PQELSQDSFGSQASSAPSMTSSKGGQEDMNLS----LQSRPSSLPDLSGSIDD 648
P + L+Q +A P+ S + L Q SSLP LS
Sbjct: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
Query: 649 LPMGTEGALSPGVSTS---GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPAS 705
+ T ++ P S G SSQ SN + P +P S LP PSP P SP +
Sbjct: 440 QQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNVSSGP-APSPSSFLP---SPSPQPSQSPVT 494
Query: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765
+R+ PG P PS S+M P+ SS A+++ Y+ + Q+ +Y P
Sbjct: 495 ---ARTPQNFSVPSPGPLNTPVNPS----SVMSPA--GSSQAEEQQYLDKLKQLSKYIEP 545
Score = 61.2 bits (147), Expect = 1e-08
Identities = 111/416 (26%), Positives = 140/416 (33%), Gaps = 67/416 (16%)
Query: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
P ++ G + G+ + P G G GQ + Q P P+S
Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140
Query: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q
Sbjct: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197
Query: 543 QHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602
Q Q+ Q Q Q QQQ QQ Q Q Q QQ Q+ A Q + Q+
Sbjct: 198 QQFQAVVQQQQ-QLQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253
Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
Q QA A Q+ Q+ P L + + P P
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP-------PPQPQ 306
Query: 663 TSGISSSQGEQSNPAQSPFSP-------------HTSPHLPGIRGPS--PSPVGSPASVA 707
++ +Q Q P QS P +T P L +R P P P
Sbjct: 307 QPPVAQNQPSQL-PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Query: 708 QSRSGPLSPAA---VPGNQMPPR-------------PPSGQSDSIMHPSMNQSSIAQDRG 751
Q + + AA PG QM PP+ +I PS SSI R
Sbjct: 366 QQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAI--PS---SSIPLGRQ 420
Query: 752 YMQRNPQ--MPQYSSPQPGSALS-------PRQPSGGQIHTGMGSYQQNSMGSYGP 798
M + Q +P SSP PG + P QPS G S Q NS S GP
Sbjct: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP---QPGQPSSQPNSNVSSGP 473
Score = 37.4 bits (85), Expect = 0.15
Identities = 125/625 (20%), Positives = 214/625 (34%), Gaps = 124/625 (19%)
Query: 891 NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTG-PPYGQGINSMAGM--INPQGPP 947
N+K+Q + A S+ P G G G PP G G S+ GM + G P
Sbjct: 71 NKKSQASVSDPMNALQSLTGGPAA-------GAAGIGMPPRGPG-QSLGGMGSLGAMGQP 122
Query: 948 YSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSK-KSSSSTTTNE 1006
S+ G ++GMA P M + TP T++ + + + + + + +
Sbjct: 123 MSLSGQPPPGTSGMA--PHSMAVVSTA-TPQTQLQLQQVALQQQQQQQQFQQQQQAALQQ 179
Query: 1007 KITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQ 1066
+ + + + ++ ++ A +++ L ++ L +L+ ++ Q
Sbjct: 180 QQQQQQQQQFQAQQSAMQQQFQAVVQQQQQ----LQQQQQQQQHLIKLHHQNQQ-----Q 230
Query: 1067 VNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKS 1126
+ + ++ + L + ++Q Q L A PP
Sbjct: 231 IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA---------QPPIQ---------- 271
Query: 1127 QPKIQPPSPAGSGSM-QGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPL----PGMSR 1181
QP +Q P P S ++ Q Q T +PP + P SQ+PP P +S+
Sbjct: 272 QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQ 330
Query: 1182 SNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG 1241
+ ++ Q + F + + P QP + + + + APG
Sbjct: 331 AQALPGQMLYTQ-PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ-------AAQMVAPG 382
Query: 1242 SDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMS 1301
M + GGM + RA P V+ P P G P +S
Sbjct: 383 VQ--MITEALAQGGM---HIRARFPPTTAVSAIPSSSIPLGRQ-----------PMAQVS 426
Query: 1302 TGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTM 1361
+ P L +P + +P PP P SP P Q ++
Sbjct: 427 QSS-LPMLSSPSPGQQVQTPQSMPPP---------------------PQPSPQPGQPSS- 463
Query: 1362 YQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRD 1421
Q VSS P P P SPS P A P S +P P+ P+
Sbjct: 464 -QPNSNVSS-GPAPSPSSFLPSPSPQP----SQSPVTARTPQNFSVPSPGPLNTPVNPSS 517
Query: 1422 ITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDD 1481
+ P GS +A + + + K I E R M++ D
Sbjct: 518 VMSPAGSSQAEEQQYLDKLKQLSKYI---EPLRRMINK-------------------IDK 555
Query: 1482 NSIMTFNLSQLPGLLELLVEYFRRC 1506
N +LS++ LL++L + +RC
Sbjct: 556 NEDRKKDLSKMKSLLDILTDPSKRC 580
Score = 32.0 bits (71), Expect = 6.4
Identities = 36/143 (25%), Positives = 52/143 (36%), Gaps = 10/143 (6%)
Query: 1230 KDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR 1289
+D + +A SDP M++ Q GG A G+G GP Q G +
Sbjct: 67 RDIHNKKSQASVSDP-MNALQSLTGGPA-----AGAAGIGMPPRGPGQSLGGMGSLGAMG 120
Query: 1290 TEPGIGPEGNMSTGAPQPNLMP----SNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345
+ + T P+ M + P + + QQQQQQQ +
Sbjct: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
Query: 1346 QGTPSGSPFPSQQTTMYQQQQQV 1368
Q F +QQ+ M QQ Q V
Sbjct: 181 QQQQQQQQFQAQQSAMQQQFQAV 203
Score = 31.6 bits (70), Expect = 8.4
Identities = 69/312 (22%), Positives = 102/312 (32%), Gaps = 53/312 (16%)
Query: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTS-------SSMAEGG-DLKPPTP 1165
PP F A QP +QP ++Q Q Q + ++A+GG ++ P
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFP 402
Query: 1166 ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS 1225
+T S IP S S +G Q S S+ +S P+PG Q S M
Sbjct: 403 PTTAVSAIP-----SSSIPLGRQP-MAQVSQSSLPMLSS--PSPGQQVQTPQS-----MP 449
Query: 1226 YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPY 1285
P P P S P + GP A P P P
Sbjct: 450 PPPQPSPQPGQ---PSSQPNSNVSSGP-------------------APSPSSFLPSPSPQ 487
Query: 1286 DRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345
P+ N S +P P P NP S M SP+ ++QQ +
Sbjct: 488 PSQSPVTARTPQ-NFSVPSPGPLNTPVNPSSVM-SPAGSSQAEEQQYLDKLKQLSKYI-- 543
Query: 1346 QGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPA 1405
P + + + + + + ++ T PSK L + K + A +
Sbjct: 544 ------EPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKN 597
Query: 1406 SHIAPAPVQPPM 1417
P P PP+
Sbjct: 598 DMAVPTPPPPPV 609
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 105 bits (261), Expect = 6e-22
Identities = 198/833 (23%), Positives = 272/833 (32%), Gaps = 178/833 (21%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66
PA+A PPPPPP+ A Q G + A G+ S P G P
Sbjct: 295 PASAQP---PPPPPPAH---ALQHYLSCGGSYPSMGHRANLACSPLGGGEPS--PGAGEP 346
Query: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGG 126
G GA + G G + GG GA G G RP + + + GG G
Sbjct: 347 SKAGPS---GATAGASGRATGPEAAGGGGA------GGGGGGYRPIIQSPGYKTGKGGYG 397
Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
++ G PP + A P G P + A+ A Q + Q GL
Sbjct: 398 AAAGGATRPPPPRSTATPK-CQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLL---- 452
Query: 187 GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA 246
GPQ G Q S P+ S PP P+
Sbjct: 453 ----------GPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPS------------------ 484
Query: 247 AGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSAR 306
PPP + S S Q +G G P A PTA+P+L+ +
Sbjct: 485 --GPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALS 542
Query: 307 GYQGYPGGDYSGG----------------PQDG---GAGKGPAD-------MASQCWGAA 340
G+ G G GG P G G G A +AS + A
Sbjct: 543 GHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAP 602
Query: 341 AAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTP----------QPSSPMDQMGKM 390
A + AA +GG + + + + +G GG P RT Q SP G
Sbjct: 603 PGAGSYAAGAGGYKGKGDGSEL---LAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGAD 659
Query: 391 RPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPY--GSQTPQRYPMTMQGRAQSA------- 441
G S+ G G G PG PY + PQRY + R ++
Sbjct: 660 GLVGEDGAADASKGLGGSGG---AGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATA 716
Query: 442 -----MGGLSYTQQIPPYGQQGPSG-------YGQQG-QTPYYNQQSPHPQQQQPPYSQQ 488
+G L ++ P G + P G YG + + Q+SP P PP + Q
Sbjct: 717 ALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPP----PPPTAQ 772
Query: 489 PPSQTPHA---QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPS-------QQ 538
TPH + P PP PP PS H SP+P S +
Sbjct: 773 STQPTPHGLLLEAGGPDLPLVLPP------PPPQLLPSVLSHAPSPSPSASKVGVHLLEP 826
Query: 539 STTQQHPQSQPPYSQPQAQSPYQQQ--------QPQQPAPSTLSQQAAYPQPQSQ----- 585
+T PQ PP P P Q + +P P+P +++ P Q
Sbjct: 827 ATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGA 886
Query: 586 -QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG 644
+ A PP +D G+ S PS +K + S+ S L D
Sbjct: 887 LEPLPPAPGDTGVGPPNSEGKDPAGAYRS--PSPQGTKAPRFVPLTSICFPDSLLQDEER 944
Query: 645 SIDDLPMGTE---GALSPGVSTSGISSSQGE--------QSNPAQSPFSPH-------TS 686
S P E G + +G +G+ PA P+ P+
Sbjct: 945 SF--FPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAG 1002
Query: 687 PHLPGIRGPSPSPVGSPASVAQS-----RSGPLSPAAVPGNQMPPRPPSGQSD 734
P PG+ P P++V +SGP AA P PP PP+ S+
Sbjct: 1003 PETPGLGLDPNKPPELPSTVNAEPLGLIQSGP-HQAAPPPPPPPPPPPAPASE 1054
Score = 83.2 bits (204), Expect = 2e-15
Identities = 236/1048 (22%), Positives = 323/1048 (30%), Gaps = 282/1048 (26%)
Query: 34 EAGGEAAAAAAAERGEMKAAAGQESEGPAVGP------PQPLGKELQDGAESNGGG---- 83
+ G A +A + M + ES GP GP Q Q + G
Sbjct: 73 DTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFI 132
Query: 84 GGGGAGSGGGPGAE---------------------------PDLKNSNGNAGPRPALNNN 116
G GS P + P +NG P L+
Sbjct: 133 SGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLK 192
Query: 117 LTEPP-----------GGGGGGSSDGVG---APPHSAAAA-LPPPAYGFGQPYGRSPSAV 161
++ P GGG G+G PP+ PPP + S+
Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252
Query: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEP-YAGPQQNSHDHGFPNHQYNSYYPNRS 220
AAAAAA Q SP L G P A P+Q++ Y S
Sbjct: 253 AAAAAA-------EQSSPQLYNFSGAAPGPPPPERALPRQDT--------VIKHYQRPAS 297
Query: 221 AY--PPPAPAYALS--------------------SPRGG---TPGSGAAAAAGSKPPPSS 255
A PPP PA+AL SP GG +PG+G + AG PS
Sbjct: 298 AQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG----PSG 353
Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315
+ + +S ++ + A GGGG GGG ++ SP G GY G
Sbjct: 354 ATAGASGRATGPE----AAGGGGAGGGGGG---------YRPIIQSPGYKTGKGGY--GA 398
Query: 316 YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA 375
+GG + A Q G AAA A AS G+ G GGQ
Sbjct: 399 AAGGATRPPPPRSTATPKCQSLGGPAAAYATGKAS--------------GAGGAGGQAY- 443
Query: 376 RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQ 435
SP G + PQ YG Q Q P G P P G P T Q
Sbjct: 444 ------SPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGL--ATCQ 495
Query: 436 GRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQT-----PYYNQQSPHPQQQQPPYSQQPP 490
+ + G Y Q PY GP+ + Q T Y SP +
Sbjct: 496 SYSPDQLQGQLYGVQGEPY--PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSL 553
Query: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPP 550
A PS+ +P PP + +PP P P S + P
Sbjct: 554 GGGGEASPSHIIRPLQSPP--ATGRPPGVGSPGAPGKYLSSV-------------LASAP 598
Query: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYP-QPQSQQSQQTAYSQQRF----PPPQELSQ 605
+ P Y S+ A P P +++++ + Q PP+
Sbjct: 599 FLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGA 658
Query: 606 DSF--------------GSQASSAPSMTSSKGGQED-----------MNLSLQSRPSSLP 640
D GS + P T + +ED + SL ++
Sbjct: 659 DGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAAL 718
Query: 641 DLS-GSIDDLPMGTE--GALSPGVSTSGISSSQG--------EQSNPAQSPFSPHTSPHL 689
+L G + + G E G G++TS + G ++S P P + T P
Sbjct: 719 ELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTP 778
Query: 690 PGI--------------------------RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ 723
G+ PSPSP S V L PA G
Sbjct: 779 HGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL-----LEPATRDGAP 833
Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ---MPQYSSPQPGS------ALSPR 774
PP PP + + + + G P P+ S PG+ AL P
Sbjct: 834 QPPPPPPPPPPPM---PLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPL 890
Query: 775 QPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSA-------- 826
P+ G TG+G NS G P G P + P + L + +P +
Sbjct: 891 PPAPGD--TGVG--PPNSEGK-DPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERS 945
Query: 827 -----------------GMAGGI----NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGN 865
G AG +P G G P PYG PGR S G
Sbjct: 946 FFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRAS----GA 1001
Query: 866 RPYGPNMA---NMPPQVGSGMCPPPGGM 890
P P + N PP++ S + P G+
Sbjct: 1002 GPETPGLGLDPNKPPELPSTVNAEPLGL 1029
Score = 61.2 bits (147), Expect = 1e-08
Identities = 116/477 (24%), Positives = 152/477 (31%), Gaps = 96/477 (20%)
Query: 527 HQQS-PAPYPSQQSTTQQHP---------------QSQPPYSQPQAQSPYQQQQPQQPAP 570
H+Q+ AP+P Q T HP + P S S + + P QP P
Sbjct: 46 HRQAYAAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGP-QPGP 104
Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630
S S + + P Q + T P P EL +S+ PS ++ Q
Sbjct: 105 SASSLLSQFRSPSWQTAMHT-------PGPTELFISGALPGSSTFPSSSALSAYQHP--A 155
Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690
S SRP +P S S+ D P S PA SPH HL
Sbjct: 156 SFGSRPFPVPS-SLSLQDPPF----------------------SPPANGLLSPHDVLHLK 192
Query: 691 GIRGPS-PSPVGSPASVAQSRSGP--LSPAAVPGNQM-PPRPPSGQSDSIMHPSMNQSSI 746
+ P+ PS +G GP L PA P + PP PP ++ SS
Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252
Query: 747 AQDRGYMQRNPQMPQYSSPQPG----------------------SALSPRQP-------- 776
A Q +PQ+ +S PG SA P P
Sbjct: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQH 312
Query: 777 --SGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINP 834
S G + MG + G GG+ P G +P+ A ++G A G
Sbjct: 313 YLSCGGSYPSMGHRANLACSPLG--GGEPSPGAG---EPSKAGPSGATAGASGRATGPEA 367
Query: 835 MGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKT 894
G GG G G P P + G G P + C GG
Sbjct: 368 AGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGG-PAAA 426
Query: 895 QETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMG 951
T A Q PG P G++G YGQG + P YS G
Sbjct: 427 YATGKASGAGGAGGQAYSPGQPQ----GLLGP-QAYGQGFGGGQAQDLSKAPSYSGG 478
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 10/93 (10%)
Query: 482 QPPYSQQPPSQTPHAQPSYQQQPQSQPPQ----LQSSQPPYSQQPSQPPHQQSPAPYPSQ 537
+PP ++ P TP P+ Q QP PP L S P + PS PP P P P
Sbjct: 1449 EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPA 1508
Query: 538 QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570
+ P PP + P A P ++P P+P
Sbjct: 1509 MPSP---PPPPPPAAAPLAAPP---EEPAAPSP 1535
Score = 43.9 bits (102), Expect = 0.002
Identities = 67/248 (27%), Positives = 85/248 (34%), Gaps = 53/248 (21%)
Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75
PPPPPP + + G E AA + R E ES P G Q L L+
Sbjct: 838 PPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE-------ESLDPP-GAMQELLGALEP 889
Query: 76 GAESNGGGGGGGAGSGG-GPGAEPDLKNSNGNAGPRPALNNNLTEPPG------------ 122
+ G G G S G P + G PR ++ P
Sbjct: 890 LPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPT 949
Query: 123 -----GGGGGSSDGVGAPPHSA----AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
GGG G PP A A PPP PYG P A+ A
Sbjct: 950 MEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYG--PYCPGRASGA------ 1001
Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA----Y 229
G ++PGL GL+P P+ S + P S P+++A PPP P
Sbjct: 1002 -GPETPGL---------GLDPNKPPELPSTVNAEPLGLIQSG-PHQAAPPPPPPPPPPPA 1050
Query: 230 ALSSPRGG 237
S P+GG
Sbjct: 1051 PASEPKGG 1058
Score = 43.1 bits (100), Expect = 0.003
Identities = 48/186 (25%), Positives = 62/186 (33%), Gaps = 27/186 (14%)
Query: 381 SSPMDQMGKMRPQPYGGTNPYSQQQGPP-SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ 439
S D + K R ++ S PP +GP+ G P P + G
Sbjct: 1382 SDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS 1441
Query: 440 SAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499
+ G PP ++ P P +P PQ Q PP P P P
Sbjct: 1442 ANSNGTPE----PPLLEEKP---------PPTPPPAPTPQPQPPPPPPPPQPALPSPPPL 1488
Query: 500 YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559
P S PP PP P PP SP P P + P + PP +P A SP
Sbjct: 1489 VAPTPSSPPP------PPL--PPPPPPAMPSPPPPPPPAAA----PLAAPP-EEPAAPSP 1535
Query: 560 YQQQQP 565
+ P
Sbjct: 1536 EDPELP 1541
Score = 42.0 bits (97), Expect = 0.006
Identities = 69/304 (22%), Positives = 110/304 (36%), Gaps = 25/304 (8%)
Query: 1074 RELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADS-----KKSQP 1128
R L T N+ SSSAA++ +Q LY F G PP D+ ++
Sbjct: 239 RHLPTQFNLLASSSAAAAAAEQSSPQLYNFS-GAAPGPPPPERALPRQDTVIKHYQRPAS 297
Query: 1129 KIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLK-------PPTPASTPHSQIPPLPGMSR 1181
PP P + ++Q + + SM +L P+P + S+ P +
Sbjct: 298 AQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAG 357
Query: 1182 SN--SVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSM-NTSDMMGRMSYEPNKDPYGSMRK 1238
++ + G + A G+ + +PGY+ G + P + +
Sbjct: 358 ASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKC 417
Query: 1239 APGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEG 1298
P + G G G +A PG +GP+ YG + + + +
Sbjct: 418 QSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQ---AYGQGFGGGQAQ-DLSKAP 473
Query: 1299 NMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQ---QQRHDSYGNQFSTQGTPSGSPFP 1355
+ S G PQP P P G+ + Y P Q Q Q Q G +QG P+ SP
Sbjct: 474 SYSGGPPQPPSGP--PPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSL 531
Query: 1356 SQQT 1359
S T
Sbjct: 532 SYST 535
Score = 40.0 bits (92), Expect = 0.024
Identities = 28/104 (26%), Positives = 36/104 (34%), Gaps = 11/104 (10%)
Query: 498 PSYQQQPQSQPPQLQSSQPPY-----SQQPSQPPHQQSPAP-YPSQQSTTQQHPQSQPPY 551
PS +PP L+ PP + QP PP P P PS P S PP
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499
Query: 552 SQPQAQSPYQQQQPQQPAPSTL-----SQQAAYPQPQSQQSQQT 590
P P P P P+ ++ A P P+ + T
Sbjct: 1500 PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT 1543
Score = 39.7 bits (91), Expect = 0.031
Identities = 54/236 (22%), Positives = 81/236 (34%), Gaps = 33/236 (13%)
Query: 549 PPYSQPQAQSP------YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602
PP S P++ P Q Q P PA A+ + ++ ++ P P +
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCK 1364
Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
+ + PS +S + N LQ S+ ++DD P+
Sbjct: 1365 RLDEELKRNLETLPSFSSDEEDSVAKNRDLQE---SISSAISALDDPPLA---------G 1412
Query: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSP--AAVP 720
S+ G PA + P P LPG+ PS + G+P P +P A P
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGP---PPLPGL--PSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQP 776
Q PP PP Q P + + +P P P P + SP P
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPT--------PSSPPPPPLPPPPPPAMPSPPPP 1515
Score = 39.7 bits (91), Expect = 0.031
Identities = 36/138 (26%), Positives = 46/138 (33%), Gaps = 14/138 (10%)
Query: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH-QQSPAPYPSQQSTT 541
PP + + TP P PP L S +PP ++ P P P T
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 542 QQHPQSQPPYSQPQAQSP--YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPP 599
Q P PP QP SP P P P L P P + S PP
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP----PPPPAMPSPPP-------PP 1516
Query: 600 PQELSQDSFGSQASSAPS 617
P + + + +APS
Sbjct: 1517 PPAAAPLAAPPEEPAAPS 1534
Score = 37.7 bits (86), Expect = 0.12
Identities = 198/898 (22%), Positives = 286/898 (31%), Gaps = 174/898 (19%)
Query: 591 AYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650
A+ Q+ PPP +Q + P + G D+ L L P L L + P
Sbjct: 758 AFLQKSPPPPPPTAQST-----QPTPHGLLLEAGGPDLPLVLPPPPPQL--LPSVLSHAP 810
Query: 651 MGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSP-----HLP--GIRGPSPSPVGSP 703
+ A GV ++ G P P P P HL G+ +PSP P
Sbjct: 811 SPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRP 870
Query: 704 ASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ----- 758
+S P + + G + P PP+ + P+ A Y +PQ
Sbjct: 871 E---ESLDPPGAMQELLG-ALEPLPPAPGDTGVGPPNSEGKDPAG--AYRSPSPQGTKAP 924
Query: 759 --MPQYSSPQPGSALSPRQPSGGQIHTGM-GSYQQNSMGSYGPQGGQYGPQGGYPRQPNY 815
+P S P S L + S M G + G GP + P+ G P
Sbjct: 925 RFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984
Query: 816 NALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANM 875
A G A G P G + P PP P ++ +G GP+ A
Sbjct: 985 PAYDPYGPYCPGRASGAGPETPGLGL--DPNKPPE---LPSTVNAEPLGLIQSGPHQAAP 1039
Query: 876 P-----PQVGSGMCPPPGGMNR----KTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926
P P + P GG+ T+ + + + ++ R P + +
Sbjct: 1040 PPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKK------ 1093
Query: 927 GPPYGQGINSMAGMINPQGP------PYSMGGTMANNSAGMAASPEMMGLGDVKLTPATK 980
Y Q A P P + +++ + A SP LGD+ P
Sbjct: 1094 --LYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSP----LGDIDFCPP-- 1145
Query: 981 MNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTN 1040
N DG + K K+ + G P R L +
Sbjct: 1146 -NPGPDGPRRRGRKPTKAKRDGPPRPR--------GRPRI-----RPLEVPTTAGPASAS 1191
Query: 1041 LPAVG-RKPLDLYRLYVSVKEIGGLTQVNKNK----KWRELATNLNVGTSSSAA------ 1089
P G +KP R E G T++ K K +GTSS A
Sbjct: 1192 TPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDH 1251
Query: 1090 ----SSLKKQYIQCLYAFECKIERGEDPPPDI---FAAA--DSKKSQPKIQPPSPAGSGS 1140
SSL ++ I E KI+ E+ P++ F A+ D KS + P AG
Sbjct: 1252 NSLDSSLTREKI------EAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTP 1305
Query: 1141 MQGPQTPQSTSSSM-AEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTF 1199
P P+S S+ A G +PP + PH G+ + + G S
Sbjct: 1306 PLSP--PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPC 1363
Query: 1200 QKRNS-MTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGS--DPFMSSGQGPNGGM 1256
++ + + N PS ++ + S N+D S+ A + DP P G
Sbjct: 1364 KRLDEELKRNLETLPSFSSDE---EDSVAKNRDLQESISSAISALDDP-------PLAGP 1413
Query: 1257 GDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDS 1316
D S GP L A P GP PG+ P N S G P+P L+ P
Sbjct: 1414 KDT-STPDGPPLAPAAAVP-------GPPPL----PGL-PSAN-SNGTPEPPLLEEKP-- 1457
Query: 1317 GMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPR 1376
PP TP +P P Q Q + P+P P
Sbjct: 1458 --------PP---------------------TPPPAPTPQPQPPPPPPPPQPALPSPPPL 1488
Query: 1377 PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQP 1434
+SP P PP P + P PP + PP A P
Sbjct: 1489 VAPTPSSPPPPPL-----------PPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 34.3 bits (77), Expect = 1.3
Identities = 29/108 (26%), Positives = 42/108 (38%), Gaps = 25/108 (23%)
Query: 16 PPPPPPSELKKAEQQQREEA--------GGEAAAAAAAERGEMKAAAGQESEG------- 60
P P PS L+ E+++ +E GE A + R E A GQ +
Sbjct: 1727 PAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARP 1786
Query: 61 ---PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNG 105
A PP+ K L++ GG GG PG+ D ++S G
Sbjct: 1787 TKVKAEPPPKKRKKWLKEA-------GGNATAGGGPPGSSSDSESSPG 1827
>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
Length = 1604
Score = 103 bits (258), Expect = 1e-21
Identities = 257/1057 (24%), Positives = 340/1057 (32%), Gaps = 181/1057 (17%)
Query: 55 GQESEGPAVGP---PQPLGKELQDGAESNGG--GGGGGAGSGGGPG-----------AEP 98
G++ E A+GP P G++ Q G + +GG G G G G PG +P
Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDP 437
Query: 99 DLKNSNGNAG-PRPALNNNLTEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQP 153
G AG P P L PPG G G+ G PP ++ +P G+P
Sbjct: 438 GFVGPEGLAGEPGPP---GLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKP 494
Query: 154 YGR--------SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP---QQNS 202
G+ P V F G PG G G P G Q
Sbjct: 495 -GKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPG----PKGEPGDPVPARGDPGIQGIK 549
Query: 203 HDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG-SGAAAAAGSKPPPSSSASASS 261
+ G P +S + + + SP G PG G A G K + A
Sbjct: 550 GEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGP 609
Query: 262 SSSSFAQQRFGAMGGGGPSAAGGGTPQP-TATPTLNQL---------LTSPSSARGYQGY 311
+ S G G GP+ G +P P L+ L L PS +G G
Sbjct: 610 AGSP------GPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP 663
Query: 312 PG-------------------GDYSGGPQDGG----------AGKGPADMASQCWGAAAA 342
PG GD +G P D G +G+ + G
Sbjct: 664 PGFGLPGKQGKAGERGLKGQKGD-AGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGD 722
Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSG-GGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPY 401
A + G P PG G G + + R +P P G Q G
Sbjct: 723 GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQP----GLPGVQGPPGLKGV 778
Query: 402 SQQQGPP----SGPQQGHGYPGQP--YGSQTPQRYP-MTMQGRAQSAMGGLSYTQQIPPY 454
+ GPP GPQ G PG P G P+ P T + AQ + G T + P
Sbjct: 779 QGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPP 838
Query: 455 GQ--QGPSGY-GQQGQTPYY---NQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQP 508
G GP G GQQGQT ++ P ++ +P P + P +
Sbjct: 839 GASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP----SQGDLIFSGMPGAPG 894
Query: 509 PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP-QSQPPYSQPQAQSPYQQQQPQQ 567
+ SS P Q P P P P Q + QP + P +Q +
Sbjct: 895 LWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKS 954
Query: 568 PAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQ-----------DSFGSQASSAP 616
+ Q A+P ++ ++ P +Q ++ G + P
Sbjct: 955 ICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDP 1014
Query: 617 SMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL----PMGTEGAL-SPGV-------STS 664
S G L Q P + GS P G GA+ SPG+ +
Sbjct: 1015 GCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLT 1074
Query: 665 GISSSQGEQSNPAQSPFSPHTS-PHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ 723
G++ +GE P Q + T P LPGI+G GS + GP PG++
Sbjct: 1075 GLTGDKGEPGPPGQPGYPGATGPPGLPGIKG-ERGYTGSAGE--KGEPGP------PGSE 1125
Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQ--PGSALSPRQPSGGQI 781
P PP S D+G+ Q P P P PG SP P G Q
Sbjct: 1126 GLPGPPGPAGPRGERGPQGNSGEKGDQGF-QGQPGFPGPPGPPGFPGKVGSP-GPPGPQA 1183
Query: 782 HTGMGSYQQNS--MGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGI 832
G + S GS GP G G GP G G +P P AG G +
Sbjct: 1184 EKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPG----PAGPPGLM 1239
Query: 833 NPMGAGGQMHGQPGIP-PYGTL----PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
P G G+ G PG+P P G PPG P P G P P
Sbjct: 1240 GPPGFKGKT-GHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGP 1298
Query: 888 GGMNRKTQETAVAMH----------VAANSIQNRPPGYPNM-----NQGGMMGTGPPYGQ 932
G +AV + +A Q PPG+P G GPP Q
Sbjct: 1299 PGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQ 1358
Query: 933 GINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMG 969
G G G G AGM P G
Sbjct: 1359 GFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395
Score = 87.4 bits (215), Expect = 1e-16
Identities = 245/1045 (23%), Positives = 333/1045 (31%), Gaps = 181/1045 (17%)
Query: 10 ASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPL 69
A S G P P P+ +K A+ + E A + + G+++ A G G P P
Sbjct: 610 AGSPGPPGPVGPAGIKGAKGEPCEPC----PALSNLQDGDVRVVALPGPSGEK-GEPGPP 664
Query: 70 GKELQDGAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNL-TEPPGGGGG 126
G L G + G G G G G PG +P + G RP L+ + P G G
Sbjct: 665 GFGLP-GKQGKAGERGLKGQKGDAGNPG-DPGTPGTTG----RPGLSGEPGVQGPAGPKG 718
Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRS---PSAVAAAAAAVFHQQHGGQQSPGLAA 183
DG A P S + A GQP + P V G Q PGL
Sbjct: 719 EKGDGCTACP-SLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKG 777
Query: 184 LQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGA 243
+Q G GPQ G P Q P P + +G G
Sbjct: 778 VQGEPGPPGRGVQGPQGEPGAPGLPGIQ---------GLPGPRGPPGPTGEKGAQGSPGV 828
Query: 244 AAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTS 301
A G PP +S S Q + G G G G G P + P+ L+ S
Sbjct: 829 KGATGPVGPPGASVSGPPGRDG-QQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFS 887
Query: 302 PSSARGYQGYPG----GDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRS 357
G G PG + GPQ GP G
Sbjct: 888 -----GMPGAPGLWMGSSWQPGPQGPPGIPGPP-------GPPGVPGLQGV--------- 926
Query: 358 HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGP----PSGPQQ 413
PG++G GQP S P++Q + G Q+ P G +
Sbjct: 927 ------PGNNGLPGQPGLTAELGSLPIEQH---LLKSICGDCVQGQRAHPGYLVEKGEKG 977
Query: 414 GHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ--IPPYGQQGPSGY-GQQGQT-P 469
G PG P Q + + RA+ A G S + G GP G GQ+G+ P
Sbjct: 978 DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037
Query: 470 YYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQ--------------PQSQPPQLQSSQ 515
+ SP P P +P P Q + P QP ++
Sbjct: 1038 PGMRGSPGPPGPIGPPGFPGAVGSP-GLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATG 1096
Query: 516 PP----------------YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559
PP +P P + P P ++ PQ S +
Sbjct: 1097 PPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGN---SGEKGDQG 1153
Query: 560 YQQQQ--PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPS 617
+Q Q P P P + P P Q+++ + R P S G P+
Sbjct: 1154 FQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGI-RGPSGLPGSPGPPGPPGIQGPA 1212
Query: 618 MTSSKGGQEDM-NLSLQSRPSSLPDLSGSIDDLPMGTEGALS-PGV----------STSG 665
G++ L P+ P L G P G +G PG+ G
Sbjct: 1213 GLDGLDGKDGKPGLRGDPGPAGPPGLMG-----PPGFKGKTGHPGLPGPKGDCGKPGPPG 1267
Query: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSR---------SGPLSP 716
+ G + P P P PG GP P P G P S +G
Sbjct: 1268 STGRPGAEGEPGA--MGPQGRPGPPGHVGP-PGPPGQPGPAGISAVGLKGDRGATGERGL 1324
Query: 717 AAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQP 776
A +PG PP P + + + +G+ P PG+A Q
Sbjct: 1325 AGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYG-----PPGPKGDPGAAGQKGQ- 1378
Query: 777 SGGQIHTGM--GSYQQNSMGSYGPQG--------GQYGPQG--GYPRQP-------NYNA 817
+G + GM G + SMG GP G G GP G G P P NY+
Sbjct: 1379 AGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDE 1438
Query: 818 LPN------ANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPN 871
+ MA + M +M PG P PPG+ RP P
Sbjct: 1439 IKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPG----PPGK---DGAPGRPGAPG 1491
Query: 872 MANMPPQVG----SGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMG-T 926
+P Q+G G+ G K ++ + + +A + PPG G MG T
Sbjct: 1492 SPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGAT 1551
Query: 927 GPPYGQGINSMAGMINPQGPPYSMG 951
GP QGI + G P G P G
Sbjct: 1552 GPMGQQGIPGIPGPPGPMGQPGKAG 1576
Score = 77.8 bits (190), Expect = 1e-13
Identities = 238/1020 (23%), Positives = 308/1020 (30%), Gaps = 163/1020 (15%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGG---EAAAAAAAERGEMKAAAGQESEGPAV 63
P G P P P+ Q + E G ++ A+ A + P
Sbjct: 524 PGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGF 583
Query: 64 GPPQPLGKELQDGAESNGG--GGGGGAGSGGGPG--AEPDLKNSNGN-AGPRPALNNNLT 118
G P G+ G + G G G AGS G PG +K + G P PAL+N
Sbjct: 584 GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643
Query: 119 EPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQS 178
G V P S P P GFG P G+Q
Sbjct: 644 --------GDVRVVALPGPSGEKGEPGPP-GFGLP---------------------GKQG 673
Query: 179 PGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG-- 236
G GL+ G N D G P + P S P + P G
Sbjct: 674 -------KAGERGLKGQKGDAGNPGDPGTPG---TTGRPGLSGEP------GVQGPAGPK 717
Query: 237 GTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTL 295
G G G A + + A +Q G G G P G G P P L
Sbjct: 718 GEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQ--GPEGVGRPGKPGQPGLPGVQGPPGL 775
Query: 296 NQLLTSPS----SARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG 351
+ P +G QG PG G Q +GP + + A
Sbjct: 776 KGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPV 835
Query: 352 GAQQRSHHAPMSPGSSGGGGQP-LARTPQPSSPMDQMGKMRPQ--PYGGTNPYSQQQGPP 408
G S P PG G GQ L TP P + G+ P G +S G P
Sbjct: 836 GPPGASVSGP--PGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAP 893
Query: 409 S---------GPQQGHGYPGQPYGSQTP--QRYP----MTMQGRAQSAMGGLSYTQQIPP 453
GPQ G PG P P Q P + Q + +G L Q +
Sbjct: 894 GLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLK 953
Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPS-------QTPHAQPSYQQQPQS 506
G GQ+ Y ++ Q P + P A+ + +
Sbjct: 954 -SICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEG 1012
Query: 507 QPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ 566
P + S P P P Q+ P + + PP SP
Sbjct: 1013 DPGCVGSPGLP---GPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQG 1069
Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626
+ + L+ P P Q Y PP + G S+ G E
Sbjct: 1070 ERGLTGLTGDKGEPGPPGQPG----YPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSE 1125
Query: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPF-SPHT 685
LP G P G G P G S +G+Q Q F P
Sbjct: 1126 -----------GLPGPPG-----PAGPRGERGP----QGNSGEKGDQGFQGQPGFPGPPG 1165
Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745
P PG G SP P G A + G P+ +PG+ PP PP Q + + +
Sbjct: 1166 PPGFPGKVG-SPGPPGPQAE--KGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDG 1222
Query: 746 IAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQY 803
RG P P P G + TG G GP+G G+
Sbjct: 1223 KPGLRG------------DPGPAGPPGLMGPPGFKGKTG-------HPGLPGPKGDCGKP 1263
Query: 804 GPQGGYPRQPNYNALPNANYPSA--GMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHA 861
GP G R P P A P G G + P G GQ G GI G +
Sbjct: 1264 GPPGSTGR-PGAEGEPGAMGPQGRPGPPGHVGPPGPPGQ-PGPAGISAVGL----KGDRG 1317
Query: 862 SMGNRPYGPNMANMPPQVG-SGMCPPPG-----GMNRKTQETAVAMHVAANSIQNRPPGY 915
+ G R +A +P Q G G PPG G K + P
Sbjct: 1318 ATGER----GLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAA 1373
Query: 916 PNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMG-LGDV 973
Q G G G P G G + G + P GP G A +G P + G +GD+
Sbjct: 1374 GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDM 1433
Score = 73.6 bits (179), Expect = 2e-12
Identities = 129/547 (23%), Positives = 178/547 (32%), Gaps = 97/547 (17%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA---- 62
P S G P PP P+ R E G + + ++G GP
Sbjct: 1119 PGPPGSEGLPGPPGPAG-------PRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPG 1171
Query: 63 -VGPPQPLGKELQDGAESNGGGGG--GGAGSGGGPGAE-----PDLKNSNGNAG----PR 110
VG P P G + + G+E G G G G G PG + L +G G P
Sbjct: 1172 KVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPG 1231
Query: 111 PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF----GQPYGRSPSAVAAAAA 166
PA L PPG G G+ P PP + G G+P P
Sbjct: 1232 PAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPG 1291
Query: 167 AVFHQQHGGQQSP-GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP 225
V GQ P G++A+ G G G G P H PP
Sbjct: 1292 HVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPG----------PPG 1341
Query: 226 APAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGG 285
P ++ + G PG G P +A + + R G GG G S + G
Sbjct: 1342 EPGTDGAAGKEGPPGK--QGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGP 1399
Query: 286 TPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345
P P+ RG+ G PG SG P G DM + +
Sbjct: 1400 VGPP-----------GPAGERGHPGAPGP--SGSPGLPGVPGSMGDMVN--YDEIKRFIR 1444
Query: 346 AAAASGGAQQRSHHA-----PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400
++ +++ PM ++ G P + P P
Sbjct: 1445 QEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRP----------------- 1487
Query: 401 YSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTM-----QGRAQSAMGGLSYTQQIP-PY 454
G P P G PGQ G + Q P +G G++ +P P
Sbjct: 1488 -----GAPGSP----GLPGQ-IGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPP 1537
Query: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS--YQQQP-QSQPPQL 511
G QGP GYG+ G T QQ P PP P + H PS + P + Q P +
Sbjct: 1538 GPQGPPGYGKMGATGPMGQQG-IPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPM 1596
Query: 512 QSSQPPY 518
++ + P+
Sbjct: 1597 KTMKGPF 1603
Score = 65.9 bits (159), Expect = 4e-10
Identities = 162/695 (23%), Positives = 219/695 (31%), Gaps = 115/695 (16%)
Query: 94 PGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQP 153
P AE + + N P + L PPG G +G PP + PP G P
Sbjct: 1000 PRAE-EARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEG---PPGMRGSPGPPGPIG---P 1052
Query: 154 YGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYN 213
G P AV SPGL LQ G GL G D G P
Sbjct: 1053 PG-FPGAVG---------------SPGLPGLQ--GERGLTGLTG------DKGEPGPPGQ 1088
Query: 214 SYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGA 273
YP + PP P + RG T G+A G PP S + + G
Sbjct: 1089 PGYPGATG-PPGLPG--IKGERGYT---GSAGEKGEPGPPGSEGLPGPPGPAGPRGERGP 1142
Query: 274 MGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQ--DGGAG-KGPA 330
G G G QP P G+ G G GPQ G G +GP+
Sbjct: 1143 QGNSGEKGDQGFQGQPG--------FPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPS 1194
Query: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP--------LARTPQPSS 382
+ A G + P G G G P +T P
Sbjct: 1195 GLPGSPGPPGPPGIQGPAGLDGLDGKDGK-PGLRGDPGPAGPPGLMGPPGFKGKTGHPGL 1253
Query: 383 PMDQMGKMRPQPYGGTN-PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441
P + +P P G T P ++ + GPQ G PG G P P A
Sbjct: 1254 PGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGH-VGPPGPPGQPGPAGISAVGL 1312
Query: 442 MGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPS-QTPHAQPSY 500
G T G++G +G Q P + P + PP Q + P
Sbjct: 1313 KGDRGAT------GERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGP 1366
Query: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPY-PSQQSTTQQHPQSQPPYSQPQAQSP 559
+ P + + Q+ + + P P S P P + + HP + P P
Sbjct: 1367 KGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPG- 1425
Query: 560 YQQQQPQQPAPSTLSQQAAYPQPQ--------SQQSQQTAYSQQRFPPPQELSQDSFGSQ 611
P ++ Y + + ++ AY R P E++
Sbjct: 1426 ---------VPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMA------- 1469
Query: 612 ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS-PGVSTSGISSSQ 670
+AP G +D P S P L G I G EG PGV G+ ++
Sbjct: 1470 --AAPGRPGPPG--KDGAPGRPGAPGS-PGLPGQI-----GREGRQGLPGVR--GLPGTK 1517
Query: 671 GEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730
GE+ + + G+ GP P P G P +GP+ +PG PP P
Sbjct: 1518 GEKGDIGIGIAGEN------GLPGP-PGPQGPPGYGKMGATGPMGQQGIPGIPGPP-GPM 1569
Query: 731 GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765
GQ H N S Q+ P M P
Sbjct: 1570 GQPGKAGH--CNPSDCFGAMPMEQQYPPMKTMKGP 1602
Score = 32.3 bits (72), Expect = 4.9
Identities = 57/215 (26%), Positives = 67/215 (31%), Gaps = 31/215 (14%)
Query: 1110 GEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEG--GDLKPPTPAS 1167
G PP + K P P G GP P ST AEG G + P
Sbjct: 1231 GPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGP--PGSTGRPGAEGEPGAMGPQGRPG 1288
Query: 1168 TPHSQIPP----LPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGR 1223
P PP PG + ++VG++ D + PG G
Sbjct: 1289 PPGHVGPPGPPGQPGPAGISAVGLK------GDRGATGERGLAGLPGQPGPPGHPGPPG- 1341
Query: 1224 MSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGG 1283
EP D PG F GP G GDP A G R P GG
Sbjct: 1342 ---EPGTDGAAGKEGPPGKQGF----YGPPGPKGDP---GAAGQKGQAGEKGRAGMP-GG 1390
Query: 1284 PYDRVRTEPGIGPEGNMS----TGAPQPNLMPSNP 1314
P P +GP G GAP P+ P P
Sbjct: 1391 PGKSGSMGP-VGPPGPAGERGHPGAPGPSGSPGLP 1424
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 103 bits (257), Expect = 2e-21
Identities = 258/1150 (22%), Positives = 362/1150 (31%), Gaps = 190/1150 (16%)
Query: 353 AQQRSHHAPMS-PGSSGGGGQPLARTPQPSSP----MDQMGKMRPQPYGGTNPYSQQQGP 407
AQ RS M+ P +G + A P S P M+ + P G N S P
Sbjct: 140 AQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPP--GGNVSSSMMAP 197
Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ 467
P+ QP +TP+ P + + GL QQ P G P + Q
Sbjct: 198 GPNPEL------QP---RTPR--PASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPV 246
Query: 468 TPYYNQQS-----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522
+ N+Q P QQQQ QQ Q Q QQQ Q++PPQ Q P +P
Sbjct: 247 S--VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRP 304
Query: 523 SQPPHQQSPAP--YPSQQSTTQQHPQSQ---------PPYSQPQAQSPYQQQQPQQPAPS 571
Q P P + S Q P +Q + + P QQQ +P+ +
Sbjct: 305 QFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA 364
Query: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631
T+ + P P SQQ + + FP Q +AP M S +GG +
Sbjct: 365 TVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQ-------FTAPQMKSLQGGPSRVPTP 417
Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPG 691
LQ P L+ + P + + G S SS Q+ P P +P G
Sbjct: 418 LQQ-----PHLT---NKSPASSPSSFQQG---SPASSPTVNQTQQQMGPRPPQNNPLPQG 466
Query: 692 IRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751
+ PV SP + G + P + Q PP Q +HP + G
Sbjct: 467 FQ----QPVSSPGRNPMVQQGNVPPNFMVMQQQPP----NQGPQSLHPGLGGMPKRLPPG 518
Query: 752 YM--QRNP-----QMPQYSSPQPGSALSPR-------QPSGGQ-----------IHTGMG 786
+ Q NP Q+P ++ PG++ +P+ Q +GGQ H
Sbjct: 519 FSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPN 578
Query: 787 SYQQNSMGSYGPQGGQYGPQGGYPR--QPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844
Q + MG +G Q G P+ N P PS M + + GQM Q
Sbjct: 579 MMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQ 638
Query: 845 PG-IPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------------QVGSGMCPPPGGM 890
G + P + R G P N+ P Q G M P M
Sbjct: 639 QGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQM 698
Query: 891 -----NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPY---GQGINSMAGMIN 942
Q+ + + N +Q + NQ +M GP G N M+
Sbjct: 699 MGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVM-PGPAQIMRGPTPNMQGNMVQ 757
Query: 943 PQGPPYSMGGTMANNSAGMAASP-EMMGLGDVKLTPATKMNNKAD--GTPKTESKSKKSS 999
G M G M + SP ++MG+ L P + A G P T + + S
Sbjct: 758 FTG---QMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSL 814
Query: 1000 SSTTTNEKITKLYEL-----------------------------GGEPERKMWVDRYLAF 1030
S + I + + G +M + F
Sbjct: 815 SQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGF 874
Query: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090
K + +T+ V D+ + V T NK KK + N
Sbjct: 875 PVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKN--------- 925
Query: 1091 SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPS--PAGSGSMQGPQTPQ 1148
+Q + +E + PP + S PK+ S P G S Q P
Sbjct: 926 --SQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPL 983
Query: 1149 STSSSMAEGGDLKPPTP------ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKR 1202
PP P P Q PP P +S Q
Sbjct: 984 QQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQS-----QQQQQQQQQMMMMLM 1038
Query: 1203 NSMTPNPGYQP-SMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYS 1261
P P S N G ++ + + P + GS P M S QGP P
Sbjct: 1039 MQQDPKSVRLPVSQNVHPPRGPLNPDSQRMP----MQQSGSVPVMVSLQGPASVPPSP-D 1093
Query: 1262 RAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSP 1321
+ P N +G Y P P M A P S S P
Sbjct: 1094 KQRMPMPVNTPLGSNSRKMV---YQESPQNPSSSPLAEM---ASLPEASGSEAPSVPGGP 1147
Query: 1322 SRYP-----PQQQQQQQQRHDSYGNQFSTQG-TPSGSPFPSQQTTMYQQQQQVSSPAPLP 1375
+ P PQ Q +TQG TP P S ++ V++P
Sbjct: 1148 NNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTS 1207
Query: 1376 RP-MENRTSP 1384
RP NR SP
Sbjct: 1208 RPKTPNRASP 1217
Score = 101 bits (252), Expect = 7e-21
Identities = 342/1600 (21%), Positives = 503/1600 (31%), Gaps = 356/1600 (22%)
Query: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60
+ A+ + A + +PPPP P ++A Q + G+ A + +G
Sbjct: 357 LQARPSLATVQTPSHPPPPYPFGSQQASQAHTN-------FPQMSNPGQFTAPQMKSLQG 409
Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNL--- 117
P PL Q + + G P + P + + GPRP NN L
Sbjct: 410 GPSRVPTPLQ---QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQG 466
Query: 118 ---------------------------TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF 150
+PP G G+G P PP +
Sbjct: 467 FQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRL-----PPGFSA 521
Query: 151 GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSH--DHGFP 208
GQ + A G Q +Q GG G AGP QN HG P
Sbjct: 522 GQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQG----AGPPQNQMQVSHGPP 577
Query: 209 NHQYNSY------YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASS- 261
N S N+ A P LS+ + G P G PPS
Sbjct: 578 NMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQ-GQPQQG---------PPSQLMGMHQQ 627
Query: 262 ---SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG 318
S QQ+ G + P P ++ PS G P
Sbjct: 628 IVPSQGQMVQQQ-GTLNPQNPMILSRAQLMPQG----QMMVNPPSQNLG----PSPQRMT 678
Query: 319 GPQDGGAGKGPADMA--SQCWGAAAAA----------AAAAAASGGAQQ--RSHHAPMSP 364
P+ + +GP MA +Q G G QQ + + + P
Sbjct: 679 PPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMP 738
Query: 365 GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGP-PSGPQQGHGYPGQPYG 423
G + + R P P+ M + Q G P QQGP + P Q G GQ
Sbjct: 739 GPA-----QIMRGPTPNM-QGNMVQFTGQMSGQMLP---QQGPVNNSPSQVMGIQGQVLR 789
Query: 424 SQTPQRYPMTMQG-RAQSAMGGLSYTQQIPPYGQQ-----GPSGYGQQGQTPYYNQQSPH 477
P + G A +A +S +Q +P Q P QG + N S H
Sbjct: 790 PPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGH 849
Query: 478 PQQQQPPYS--------------------------------------------------- 486
P+S
Sbjct: 850 GMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNT 909
Query: 487 --QQPPSQTPHAQPSYQQQ----PQSQPPQL-QSSQPPY---------SQQPSQPPHQQS 530
+P + P + QQ P ++P L ++ QPP + P P
Sbjct: 910 NANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNR 969
Query: 531 PAPYPSQ---QSTTQQHPQS---------QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAA 578
P YPSQ Q QQ P QPP QPQ Q P QQQ P P + QQ
Sbjct: 970 PPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQ 1029
Query: 579 YPQ-------PQSQQSQQTAYSQQRFPPPQELSQDSFG---SQASSAPSMTSSKGGQEDM 628
Q Q +S + SQ PP L+ DS Q+ S P M S +G
Sbjct: 1030 QQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG----- 1084
Query: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688
P+S+P S +PM +P S S Q NP+ SP + S
Sbjct: 1085 -------PASVPP-SPDKQRMPMPVN---TPLGSNSRKMVYQESPQNPSSSPLAEMAS-- 1131
Query: 689 LPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG-QSDSIMHPSMNQSSI 746
LP G +PS G P ++ P + + G + P P S Q + P +N S+
Sbjct: 1132 LPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVN--SL 1189
Query: 747 AQDRGYMQRNPQMP-QYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGP 805
G+ N P Q S P+ + SPR P Q + S S P+
Sbjct: 1190 PSSHGHHFPNVAAPTQTSRPKTPNRASPR-PYYPQTPNNRPPSTEPSEISLSPERLNASI 1248
Query: 806 QGGYPRQPNYNALPNANYPSAGMAGGINP--MGAGGQMHGQPGIPPYGTLPP-------- 855
G +P Q N P N G+NP + A GQ + P P
Sbjct: 1249 AGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSV 1308
Query: 856 ----GRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNR 911
G+ S++ R N P P PG N K + +A A +QN
Sbjct: 1309 VVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNV 1368
Query: 912 PPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYS---MGGTMANNSAGM------- 961
+ + P G N+ +NPQ S +GG + +N +
Sbjct: 1369 ELPRNVLVSPTPLANPPVPGSFPNNSG--LNPQNSTVSVAAVGGVVEDNKESLNVPQDSD 1426
Query: 962 ----AASPEMMGLGDVKLTPATKM-------NNKADGTPK--------TESKSKKSSSST 1002
+ E + + ++K PA ++ +K DG P E+K+ S +
Sbjct: 1427 CQNSQSRKEQVNI-ELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMR 1485
Query: 1003 TTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNL----PAVGRKPLDLYRLYVSV 1058
+++L + G P + K G+T+L P V + L + ++
Sbjct: 1486 EAPTSLSQLLDNSGAPNVTI-----------KPPGLTDLEVTPPVVSGEDLKKASVIPTL 1534
Query: 1059 KEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIF 1118
+++ +E + +LN+ S+ SSL + E + P I
Sbjct: 1535 QDLSSS---------KEPSNSLNLPHSNELCSSLVHPELS---------EVSSNVAPSIP 1576
Query: 1119 AAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTP-HSQIPPLP 1177
S I P P ++ P +TS++ T A+ P H Q +
Sbjct: 1577 PVMSRPVSSSSISTPLPPNQITVFVTSNPITTSAN----------TSAALPTHLQSALMS 1626
Query: 1178 GMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMR 1237
+ + G + ++G + P + +N+S ++ M GS
Sbjct: 1627 TVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVF---INSSSIIQVMK--------GSQP 1675
Query: 1238 KAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGI--- 1294
+ P + N G+ P GP H P + P
Sbjct: 1676 STIPAAPLTT-----NSGLMPPSVAVVGP----------LHIPQNIKFSSAPVPPNALSS 1720
Query: 1295 GPEGNMSTGAP-------QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347
P N+ TG P P +PS P + +PP QQ ++ D Q +T
Sbjct: 1721 SPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPP-VQQVKELNPDEASPQVNTSA 1779
Query: 1348 TPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKS 1387
+ P SQ TTM S P NR SP S
Sbjct: 1780 DQNTLP-SSQSTTMVSPLLTNS-----PGSSGNRRSPVSS 1813
Score = 50.1 bits (118), Expect = 2e-05
Identities = 87/370 (23%), Positives = 124/370 (33%), Gaps = 83/370 (22%)
Query: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI 1173
PP + + SQ P + G PQ +GG + PTP PH
Sbjct: 372 PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKS------LQGGPSRVPTPLQQPH--- 422
Query: 1174 PPLPGMSRSNSVGIQDAFNDGSDSTF----QKRNSMTPNP--------GYQ-----PSMN 1216
++ + +F GS ++ Q + M P P G+Q P N
Sbjct: 423 -----LTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRN 477
Query: 1217 TSDMMGRM--------SYEPNKDPY-------GSMRKAPGSDPFMSSGQ-GPNGGMGD-P 1259
G + PN+ P G ++ P P S+GQ PN G P
Sbjct: 478 PMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLP---PGFSAGQANPNFMQGQVP 534
Query: 1260 YSRAAGPG-LGNVAMGPRQHYPYGG------PYDRVRTEPG---------IGPEGNM--- 1300
+ A PG G + Q+ + G P ++++ G +G GNM
Sbjct: 535 STTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQ 594
Query: 1301 ---STGAPQPNL--MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGT--PSGSP 1353
++G PQ NL M P G P Q QQ S G QGT P
Sbjct: 595 QAGTSGVPQVNLSNMQGQPQQGP------PSQLMGMHQQIVPSQGQMVQQQGTLNPQNPM 648
Query: 1354 FPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV 1413
S+ M Q Q V+ P+ P R +P K G +M +
Sbjct: 649 ILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQ 708
Query: 1414 QPPMIRRDIT 1423
Q PMI + +T
Sbjct: 709 QNPMIEQIMT 718
Score = 35.0 bits (79), Expect = 0.76
Identities = 33/113 (29%), Positives = 41/113 (36%), Gaps = 21/113 (18%)
Query: 1325 PPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQ---------VSSPAPLP 1375
PPQ QQQ Q Q Q P P PSQ + QQQQQ P +
Sbjct: 997 PPQPPQQQPQ------PQLPQQQQP---PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVR 1047
Query: 1376 RPMENRTSPSKSPFLHSGMKM---QKAGPPVPASHIAPAPVQPPMIRRDITFP 1425
P+ P + P +M Q PV S PA V P ++ + P
Sbjct: 1048 LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMP 1100
Score = 34.7 bits (78), Expect = 0.99
Identities = 41/173 (23%), Positives = 56/173 (32%), Gaps = 20/173 (11%)
Query: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308
G G + M + A+GPG+ R + P V PG +M P P
Sbjct: 154 GAGNSVRMEAGFPMASGPGI------IRMNNPA-----TVMIPPGGNVSSSMMAPGPNPE 202
Query: 1309 LMPSNPDSGMYSPSRYPPQQQQQ-QQQRHDSYG--------NQFSTQGTPSGSPFPSQQT 1359
L P P S + P QQQ H S S + + FP Q
Sbjct: 203 LQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQ 262
Query: 1360 TMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAP 1412
QQQQQ + + + ++ P H + Q P A P P
Sbjct: 263 QQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVP 315
Score = 33.9 bits (76), Expect = 1.7
Identities = 76/410 (18%), Positives = 134/410 (32%), Gaps = 52/410 (12%)
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557
P+ Q S+ P + P ++ S H + + ++ P P S+P +
Sbjct: 1532 PTLQDLSSSKEPSNSLNLPHSNELCSSLVHPEL------SEVSSNVAPSIPPVMSRPVSS 1585
Query: 558 SPYQQQQP---------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608
S P P ++ + AA P T + +S+
Sbjct: 1586 SSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQS 1645
Query: 609 GSQASSAPSMTSSK--GGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE-GALSPGVSTSG 665
+Q+++ P + + + S+PS++P P+ T G + P V+ G
Sbjct: 1646 AAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAA-------PLTTNSGLMPPSVAVVG 1698
Query: 666 -ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724
+ Q + + A P + +S P I+ P + S A+ Q S P + + V +
Sbjct: 1699 PLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHP 1758
Query: 725 PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784
P + + P +N S+ Q + + PGS+ + R P G
Sbjct: 1759 PVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKG 1818
Query: 785 ---------MGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPM 835
+ + GS QYG G Q P G +
Sbjct: 1819 KVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAP----------GLMGTE 1868
Query: 836 GAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCP 885
++ + PP TL M + P GP A+ P + G P
Sbjct: 1869 QLSTELDSKTPTPPAPTL-------LKMTSSPVGPGTASAGPSLPGGALP 1911
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 103 bits (256), Expect = 2e-21
Identities = 288/1239 (23%), Positives = 401/1239 (32%), Gaps = 273/1239 (22%)
Query: 97 EPDLKNSNGNAGPRP------ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAAL-PPPAYG 149
EP + + N G R ++N + P GG P A +AL PP G
Sbjct: 8 EPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPG-----PVDPAMSALGEPPILG 62
Query: 150 FG-QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSGGG-GGLEPYAGPQQNSHDHG 206
+PYG FH + H + GL A G GG +P+ G + H H
Sbjct: 63 MNMEPYG-------------FHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPH- 108
Query: 207 FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS---ASASSSS 263
Q++ ++ P P + G GAA GS+PP + + S
Sbjct: 109 ----QHHPHFGGNFGGPDPGASCLHGGRLLGY--GGAAGGLGSQPPFAEGYEHMAESQGP 162
Query: 264 SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG----- 318
SF QR G + S A P L SP+ A + G P S
Sbjct: 163 ESFGPQRPGNLPDFHSSGASSHAVPAPCLP----LDQSPNRAASFHGLPSSSGSDSHSLE 218
Query: 319 -------GPQD-------GGAGKGPADM--ASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362
G D G A G DM S G AA GGA + P
Sbjct: 219 PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278
Query: 363 SPGSSGGG---GQPLARTPQPSSPMDQ-------------------------MGKMRP-- 392
+ G G QP + PQ Q +G P
Sbjct: 279 AAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLM 338
Query: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG-----SQTPQRYPMTMQGRAQSAMGGLSY 447
QP P QQQ P PQQ P P G + P P QG A + GGL
Sbjct: 339 QPPQQAPPPPQQQPPQQPPQQ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ- 394
Query: 448 TQQIPPYGQQGPSGYGQQGQTPY----YNQQSPHPQQQQPPYSQQ--PPSQTPHAQ---- 497
GP Q Q Y +S HP + P +S Q PP Q P+ +
Sbjct: 395 --------DGGPMLPSQHAQFEYPIHRLENRSMHPYSE-PVFSMQHPPPQQAPNQRLQHF 445
Query: 498 --PSYQQ----------------------------------QPQSQPPQLQSSQPPYSQQ 521
P Y P + P PP
Sbjct: 446 DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDS 505
Query: 522 -PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP 580
PS PP Q + S Q QQ Q Q Q Q Q QQQQ +Q A + Q A+
Sbjct: 506 FPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS-- 563
Query: 581 QPQSQQSQQTAYSQQRFP------------PPQELSQDSFGSQASSAPSMTSSKGGQEDM 628
+ Q Q+ +Q +Q P P L+Q +F + S + Q+
Sbjct: 564 RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAP 623
Query: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688
+L+ +S S P D LP G SG+ + G PH
Sbjct: 624 HLAQESAWFSGPHPPPG-DLLPRRMGG--------SGLPADCG---------------PH 659
Query: 689 LPGIRGPSPSPVGSPASVAQSRSGPL-SPAAVPGNQMPPRPPS------GQSDSIMHPSM 741
P + P P P GS GPL P +PG P PS G +
Sbjct: 660 DPSL-APPPPPGGSGVLF----RGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQS 714
Query: 742 NQSSIAQDRGYMQRNPQMPQYSSP----QPGSALSPRQPSGGQI--HTGMGSYQQNSMGS 795
+ + +R P P +++ QPG P +G Q H+G G S G
Sbjct: 715 PGAGVGLPSAASERRPPPPDFATSALGGQPG---FPFGAAGRQSTPHSGPGVNSPPSAGG 771
Query: 796 YGPQGGQYGPQGGYPRQPNYNALPNANYPSAG--MAGGINPMGAGGQMHGQPGIPPYGTL 853
G G G G YP QP++ + G G N + + GQ + T
Sbjct: 772 GGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTA 831
Query: 854 PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913
+ AS+G PN+ V PP G + +Q VA N P
Sbjct: 832 CQNMI--ASLG----APNL-----NVTFNKKNPPEGKRKLSQNETDGAAVAGN------P 874
Query: 914 G---YPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
G +P G G G P G +S + P PP GT + + + ++ G
Sbjct: 875 GSDYFPGGTAPGAPGPGGPSGTS-SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG- 932
Query: 971 GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAF 1030
P + + G K +S S T +K + + GG P V
Sbjct: 933 -----KPVSGGGGRGRGRRKRDS---GHVSPGTFFDKYSAAPDSGGAP----GVSPGQQQ 980
Query: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090
A+G ++ P + S G + ++ +L +L+ G S ++S
Sbjct: 981 ASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQP--DLIGSLDGGAKSDSSS 1038
Query: 1091 ----SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSK--KSQPKIQPPSPAGSGSMQGP 1144
+ YA E ++ D P + A+ S PK+ PP G+G GP
Sbjct: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKL-PPRGVGAGE-HGP 1096
Query: 1145 QTP----------QSTSSSMAEGGDLKPPTPASTPHSQI 1173
+ P STS+ + GG P P + Q+
Sbjct: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135
Score = 82.8 bits (203), Expect = 3e-15
Identities = 279/1286 (21%), Positives = 410/1286 (31%), Gaps = 239/1286 (18%)
Query: 191 GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK 250
GL+ + PQ NS + G +N + + + APA+ P G P A +A G
Sbjct: 3 GLDQFE-PQVNSRNAGQGERNFNETGLSMNTHFK-APAFHTGGPPG--PVDPAMSALGEP 58
Query: 251 PPPSSSASASSSSSSFAQQRFGAMGGGGPSAA------GGGTPQPTATPTLNQLLTSPSS 304
P + F + + GG A GG P P S
Sbjct: 59 P----ILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG----------HPGS 104
Query: 305 ARGYQGYP--GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362
+Q +P GG++ GGP G + + A + A G P
Sbjct: 105 HHPHQHHPHFGGNF-GGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPE 163
Query: 363 SPGSSGGGGQPLART--------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414
S G G P + P P P+DQ P+
Sbjct: 164 SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQS--------------------PNRAASF 203
Query: 415 HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-------GQQGQ 467
HG P GS + P + Q A+ L Y Y + PSG+ +GQ
Sbjct: 204 HGLPSSS-GSDSHSLEPRRVTN--QGAVDSLEYN-----YPGEAPSGHFDMFSPSDSEGQ 255
Query: 468 TPYYNQQSPHPQQQQPPYSQQPPS------QTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ 521
P+Y P P S P + HAQP QQ Q Q PQ Q Q +
Sbjct: 256 LPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFE 315
Query: 522 PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ 581
+ P + S +HP QPP QA P QQQ PQQP PQ
Sbjct: 316 RFSGARKM---PVGLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQP-----------PQ 358
Query: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641
Q Q PP Q + PS GG +D L S+ +
Sbjct: 359 QQPPPPPGLLVRQNSCPPALPRPQQG----EAGTPS-----GGLQDGGPMLPSQHAQFEY 409
Query: 642 LSGSIDDLPMG--TEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHL--PGIRGPSP 697
+++ M +E S + +Q Q A + P PG G
Sbjct: 410 PIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDR 469
Query: 698 SPVGSPASVAQSRSGPLSPAA---VPGNQMPPRPPSGQSDS-IMHPSMNQSSIAQDRGYM 753
+ + + LSP+A +PG PP P S S + HP+ + S+ Q +
Sbjct: 470 CASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQ 529
Query: 754 QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQP 813
Q+ Q Q Q ++ + + M S Q RQP
Sbjct: 530 QQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR----------------LRQP 573
Query: 814 NYNALPNANYPSAGMAGGINPMGAGGQMHGQP--GIP-PYGTLPPGRMSHASMGN-RPYG 869
N L G +G GG +HG P G+ P G +G
Sbjct: 574 NLAQL-----------GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQA 622
Query: 870 PNMANMPPQVGSGMCPPPGGM-NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGP 928
P++A SG PPPG + R+ + + + PP P
Sbjct: 623 PHLAQESAWF-SGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP-------------P 668
Query: 929 PYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGT 988
P G G+ + P P G A S G+ + GLG ++ A G
Sbjct: 669 PGGSGVLFRGPLQEPMRMP-GEGHVPALPSPGLQFGGSLGGLGQLQSPGA------GVGL 721
Query: 989 PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGR-- 1046
P S+ + T+ LGG+P + T G+ + P+ G
Sbjct: 722 PSAASERRPPPPDFATSA-------LGGQPGFPFGAAGRQS-TPHSGPGVNSPPSAGGGG 773
Query: 1047 --------------KPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSL 1092
+P S ++G L+ + NK + NL + +A S+
Sbjct: 774 GSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSK--DNLFGQSCLAALSTA 831
Query: 1093 KKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQ---------- 1142
+ I L A + + PP+ K SQ + + AG+
Sbjct: 832 CQNMIASLGAPNLNVTFNKKNPPE----GKRKLSQNETDGAAVAGNPGSDYFPGGTAPGA 887
Query: 1143 -GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQK 1201
GP P TSSS ++ P S P S S + G + G +K
Sbjct: 888 PGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRK 947
Query: 1202 RNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYS 1261
R+S +PG + S P+ G P +S GQ
Sbjct: 948 RDSGHVSPG--------TFFDKYSAAPDS----------GGAPGVSPGQ----------Q 979
Query: 1262 RAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSP 1321
+A+G +G + G + P P+++ T P G + G QP+L+ S D G S
Sbjct: 980 QASGAAVGGSSAGETRGAP--TPHEKALTSPSWGKGAELLLG-DQPDLIGS-LDGGAKSD 1035
Query: 1322 SRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENR 1381
S P + + SY N+ S S P + SP PR +
Sbjct: 1036 SSSPNVGEFASDEVSTSYANE---DEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAG 1092
Query: 1382 TSPSKSPFLHSGMKMQKAGPPVPASH 1407
K+P G+ + P S+
Sbjct: 1093 EHGPKAPPPALGLGIMSNSTSTPDSY 1118
Score = 60.1 bits (144), Expect = 2e-08
Identities = 130/561 (23%), Positives = 180/561 (32%), Gaps = 112/561 (19%)
Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSG---GGPGAEPDLKNSNGNAGPRPALNNNL 117
P++ PP P G GSG GP EP G+ P+
Sbjct: 661 PSLAPPPPPG------------------GSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702
Query: 118 TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG-QPYGRSPSAVAAAAAAVFHQQHGGQ 176
GG G S G G SAA+ PP F G P AA +Q
Sbjct: 703 GGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG----RQSTPH 758
Query: 177 QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP---APAYALSS 233
PG+ + S GGGG G AYPP P+ S+
Sbjct: 759 SGPGVNSPPSAGGGGGSSGGG-------------------GGGGAYPPQPDFQPSQRTSA 799
Query: 234 PRGGTPGSGAAAAAGSKPPPSS-----SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288
+ G A + GS PSS S ++ S+ Q ++G +
Sbjct: 800 SKLG------ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP 853
Query: 289 PTATPTLNQLLTSPSSARGYQG---YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345
P L+Q T ++ G G +PGG G P G GP+ +S A+
Sbjct: 854 PEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG----GPSGTSSSGSKASGPPNP 909
Query: 346 AAAASGGAQQRSHHAPMSPGS-----SGGGGQPLARTPQPS---SPMDQMGKMRPQP-YG 396
A G + ++ + G+ SGGGG+ R + S SP K P G
Sbjct: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969
Query: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAM-------------- 442
G S Q SG G G+ G+ TP +T + A
Sbjct: 970 GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029
Query: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQ-----QSPHPQ----QQQPPYSQQPPSQT 493
GG P G+ + T Y N+ S +PQ + P P
Sbjct: 1030 GGAKSDSSSPNVGEFA----SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085
Query: 494 PHAQPSYQQQPQSQPPQL-------QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ--- 543
P + + P++ PP L +S P P H +P + T+
Sbjct: 1086 PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
Query: 544 HPQSQPPYSQPQAQSPYQQQQ 564
P P QAQ Q+QQ
Sbjct: 1146 PPDEIHPLEILQAQIQLQRQQ 1166
Score = 57.4 bits (137), Expect = 1e-07
Identities = 107/440 (24%), Positives = 143/440 (32%), Gaps = 72/440 (16%)
Query: 24 LKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES---EGPAVGPPQPLGKELQDGAESN 80
L A ++R A +A + G AAG++S GP V P +
Sbjct: 721 LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP------------S 768
Query: 81 GGGGGGGAGSGGGPGA---EPDLKNS-NGNAGPRPALNNNLTEPPGGG----GGGSSDGV 132
GGGGG +G GGG GA +PD + S +A AL+ P G +
Sbjct: 769 AGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAAL 828
Query: 133 GAPPHSAAAALPPPAYGF-----GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSG 187
+ A+L P P G+ + A G PG A +
Sbjct: 829 STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP 888
Query: 188 GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAA 245
G GG P S G PN P + +P Y L S G G P SG
Sbjct: 889 GPGG--PSGTSSSGSKASGPPNP------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940
Query: 246 AAGSKPPPSS------------SASASSSS----SSFAQQRFGAMGGGGPSAAGGGTPQP 289
+ S SA+ S S QQ GA GG + G P P
Sbjct: 941 RGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTP 1000
Query: 290 TATPTLNQLLTSPSSARGYQGYPG------GDYSGGPQDGGAGKGPADMASQCWGAAAAA 343
+ LTSPS +G + G G GG + + + AS + A
Sbjct: 1001 H-----EKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN 1055
Query: 344 AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403
++S Q A SP +G + P + G P P G S
Sbjct: 1056 EDEVSSSSDNPQALVKASRSPLVTGS-----PKLPPRGVGAGEHGPKAPPPALGLGIMSN 1110
Query: 404 QQGPPS--GPQQGHGYPGQP 421
P G G G+PG P
Sbjct: 1111 STSTPDSYGGGGGPGHPGTP 1130
Score = 52.4 bits (124), Expect = 5e-06
Identities = 85/329 (25%), Positives = 116/329 (35%), Gaps = 82/329 (24%)
Query: 20 PPSELKKAEQQQREEA------------GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67
PP +K Q + + A GG A A +++G ++ GP P Q
Sbjct: 853 PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQ 912
Query: 68 PLGKELQDG--AESNGGGGG----GGAGSGGG----------PGAEPDLKNSNGNAGPRP 111
G L ES G G GG G G G PG D ++ ++G P
Sbjct: 913 GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAP 972
Query: 112 ALNNNLTEPPGGGGGGSSDGV--GAP-PHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168
++ + G GGSS G GAP PH A P G G P +
Sbjct: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLI------- 1025
Query: 169 FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHG-FPNHQYNSYYPNR-----SAY 222
G L+ A +S + G F + + ++ Y N S+
Sbjct: 1026 ---------------------GSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064
Query: 223 PPPAPAYALSSPR-GGTP-----GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276
P A A SP G+P G GA PPP+ S+S+S +G GG
Sbjct: 1065 NPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS-TPDSYG--GG 1121
Query: 277 GGPSAAGGGTPQPTATPTLNQLLTSPSSA 305
GGP G TP L Q+ T SS+
Sbjct: 1122 GGPGHPG--------TPGLEQVRTPTSSS 1142
Score = 32.0 bits (71), Expect = 6.4
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
Query: 55 GQESEGPAVGPPQPLGKELQDGAES--NGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRP 111
G GP PP LG + + S + GGGGG G G PG E ++ + P P
Sbjct: 1090 GAGEHGPKA-PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 103 bits (256), Expect = 2e-21
Identities = 253/1049 (24%), Positives = 322/1049 (30%), Gaps = 161/1049 (15%)
Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75
PP PP S K Q ++ G + + GQ GPP LG Q
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514
Query: 76 GAESNGGGGG--GGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDG 131
G + G G G G G PGA P K G+ P + + E G G
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574
Query: 132 VGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGG 191
G P LP P G+P G F + G +PGL L G
Sbjct: 575 PGTPGQDGLPGLPGPK---GEPGG-----------ITFKGERGPPGNPGLPGLPGNIGPM 620
Query: 192 LEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPA--PAYALSSP-RGGTPGS-GAAAAA 247
P GP + G N P + P P P ++ P + G PG+ G
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGN---PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677
Query: 248 GSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG 307
G P ++ G G G P G P P P + P A G
Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPPGPKGFPGI----PGPPGAPG 728
Query: 308 YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP--- 364
G G + GP KG A A G R P P
Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788
Query: 365 ----------GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ----------- 403
G G GQP P + G P P G P Q
Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP--PGPPGIPGPIGQPGLHGIPGEKG 846
Query: 404 QQGPPS----GPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ-QIPPYGQQG 458
GPP GP G PG P G+ P P + ++ G T+ ++ G G
Sbjct: 847 DPGPPGLDVPGPPGERGSPGIP-GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG 905
Query: 459 PSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPP 517
P G G G++ + Q QP + +P P P L S+
Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965
Query: 518 YSQQPSQP--PHQQSPAPY------PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569
+ P P P P Y P Q + Q PP + P Q P
Sbjct: 966 KGE-PGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024
Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629
+P PQ + PP GS P + KG + D
Sbjct: 1025 LKGTIGDMGFPGPQGVEG----------PPGPSGVPGQPGS-----PGLPGQKGDKGDPG 1069
Query: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQSPFSPHTS-- 686
+S LP L G P G G PG GI S G+ P P +P
Sbjct: 1070 IS----SIGLPGLPG-----PKGEPGL--PGYPGNPGIKGSVGDPGLPGL-PGTPGAKGQ 1117
Query: 687 PHLPGIRG----PSPSPVGSPASVA--QSRSGPLSPAAVPGNQMPP--RPPSGQSDSIMH 738
P LPG G P P + P GP+ PG PP + GQ D I
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ-DGIPG 1176
Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSPQ-----PGSALSPRQPSGGQIHTGMGSYQQNSM 793
P+ + Q P +P S + PG +P P G + G +
Sbjct: 1177 PAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKGEPGFHGFP-GVQ 1234
Query: 794 GSYGPQG----------GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843
G GP G G GPQG P +P + LP P G+ G G G G
Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGP-PGRPGFQGLPGPEGPP-GLPGNGGIKGEKGNP-G 1291
Query: 844 QPGIPPYGTLP-----------PGRMSHASMGNRPYGPNMANMPPQVG-SGMCPPPGGMN 891
QPG+P L PGR M P P + P G SG+ PG
Sbjct: 1292 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV---PGSAG 1348
Query: 892 RKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM---GTGPPYGQGINSMAGMINPQGPPY 948
+ + + PPG P + ++ GPP G + G+ PQGP
Sbjct: 1349 PEGEPGLIG--------PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1400
Query: 949 SMGGTMANNSAGMAASPEMMGLGDVKLTP 977
G T G P G G K P
Sbjct: 1401 LPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1429
Score = 91.7 bits (226), Expect = 7e-18
Identities = 208/882 (23%), Positives = 264/882 (29%), Gaps = 165/882 (18%)
Query: 60 GPAVGPPQPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAG------ 108
GP P Q + + + G N G G G G G PG P + S G G
Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL-PGIPGSKGEPGIPGIGL 708
Query: 109 ---PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAA 165
P P + PPG G G+ PP P GF P P +
Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768
Query: 166 AAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP 225
A+ + G P G GL+ GP+ + +G P P PP
Sbjct: 769 GALGPKGDRGFPGPP----GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP 824
Query: 226 APA-----------YALSSPRG----------GTPGS----GAAAAAGSKPPPSSSASAS 260
P + + +G G PG G A G PP S
Sbjct: 825 GPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884
Query: 261 SSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLN--------QLLTSPSSARGYQG 310
+ +S G MG GP G G P + P L L P+ +G +G
Sbjct: 885 KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944
Query: 311 YPGGDYSGGPQD----GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS 366
PG GP D G G+ G + Q P PG
Sbjct: 945 EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004
Query: 367 SGGGGQP-------LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP----QQGH 415
G G P L P + MG PQ G S G P P Q+G
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064
Query: 416 ------------------------GYPGQP-----YGSQTPQRYPMTMQGRAQSAMGGLS 446
GYPG P G P T + Q + G
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124
Query: 447 YTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505
T P P G GP G P HP Q PP + P Q P+ Q+
Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184
Query: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQ-PQAQSPYQQQQ 564
QP P Q P P P+ +P + P Q P
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPG-IPGNPGLPG--PKGEPGFHGFPGVQGP--PGP 1239
Query: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGG 624
P P P+ L P PQ + Q P P+ P + + G
Sbjct: 1240 PGSPGPA-LEGPKGNPGPQGPPGRP---GFQGLPGPE------------GPPGLPGNGGI 1283
Query: 625 QEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPH 684
+ + Q LP L G D P G +G +PG G++ +G+ P
Sbjct: 1284 KGEKGNPGQPGLPGLPGLKG--DQGPPGLQG--NPG--RPGLNGMKGDPGLPGV------ 1331
Query: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744
P PG++GPS P G P PG PP PP + PS
Sbjct: 1332 --PGFPGMKGPSGVP------------GSAGPEGEPGLIGPPGPP-----GLPGPSGQSI 1372
Query: 745 SIAQDRGYMQRNPQMPQYSSPQPG--SALSPRQPSGGQIHTG-MGSYQQNSMGSYGPQGG 801
I D G P QPG P+ P G TG G +N + + GG
Sbjct: 1373 IIKGDAG--------PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1424
Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843
+ G G P QP L P G+ G P G HG
Sbjct: 1425 RKG-DPGLPGQPGTRGLDGPPGPD-GLQGPPGPPGTSSVAHG 1464
Score = 90.9 bits (224), Expect = 1e-17
Identities = 244/1051 (23%), Positives = 321/1051 (30%), Gaps = 151/1051 (14%)
Query: 13 LGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKE 72
L P P + E+ Q+ + G R G++ G P G+
Sbjct: 314 LPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373
Query: 73 LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV 132
G + G G + GP P G G ++ PPG G + G+
Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL 433
Query: 133 GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192
PP A + PP+ +P P + + G + G G G
Sbjct: 434 PGPPGPAGPHI-PPSDEICEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG-- 488
Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGS-GAAAAAGS 249
+GP G P + +P + A A + P+G G PG+ GA GS
Sbjct: 489 --ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA---TGPKGLPGIPGAPGAPGFPGS 543
Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSAR- 306
K P + G +G G G GTP P L P
Sbjct: 544 KGEPGDILTFPGMKGD-----KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598
Query: 307 -------GYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH 359
G G PG + GP G G GP + A G +
Sbjct: 599 KGERGPPGNPGLPGLPGNIGPM-GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657
Query: 360 APMSPGSSGGGGQP-------LARTP----QPSSPMDQMGKMRPQPYGGTNPYSQQQGPP 408
PG G G P L P QP P K P G P GPP
Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPP 712
Query: 409 SGPQQGHGYPGQPYGSQTPQRYPMT----------MQGRAQSAMGGLSYTQQIP------ 452
GP+ G PG P TP R + +G A+ G +P
Sbjct: 713 -GPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771
Query: 453 -PYGQQG-PSGYGQQGQTPYYNQQSPH----PQQQQPPYS---------QQPPSQTPHAQ 497
P G +G P G G+T P P Q P Q PP
Sbjct: 772 GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP----APYPSQQSTTQQHPQSQPPYSQ 553
P Q P + PP P P + SP AP P + P
Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891
Query: 554 PQAQSPY-QQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612
P + P P P + ++ P + Q Q P P
Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ---GQPGLPGP------------ 936
Query: 613 SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL-SPGV-STSGISSSQ 670
T KG + + LP G +D +G++G PG+ G+S +
Sbjct: 937 ------TGEKGSKGE---------PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981
Query: 671 GEQSNPAQSPFSPHTS--PHLPGIRGPSPSP--VGSPASVA----------------QSR 710
G Q P P P S P LPG GP +P G P + Q
Sbjct: 982 GYQGLPG-DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040
Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSA 770
GP P+ VPG P P GQ P ++ + G + P +P Y PG
Sbjct: 1041 EGPPGPSGVPGQPGSPGLP-GQKGDKGDPGISSIGLPGLPG-PKGEPGLPGYPG-NPGIK 1097
Query: 771 LSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG--GYPRQPNYNALPNANYPSAGM 828
S P + G+ Q + + G GP+G G P P P G
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGH 1156
Query: 829 AGGINPMGAGGQMHGQPGIP-PYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPP- 886
G P G G+ GQ GIP P G G GN P P + + Q G G P
Sbjct: 1157 PGQPGPPGEKGK-PGQDGIPGPAG--QKGEPGQPGFGN-PGPPGLPGLSGQKGDGGLPGI 1212
Query: 887 PGGMNRKTQETAVAMHVAANSIQN--RPPGYPNMNQGGMMGTGPPYG-QGINSMAGMINP 943
PG + H +Q PPG P G G P G G G+ P
Sbjct: 1213 PGNPGLPGPKGEPGFH-GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGP 1271
Query: 944 QGPPYSMGGTMANNSAGMAASPEMMGLGDVK 974
+GPP G G P + GL +K
Sbjct: 1272 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1302
Score = 73.2 bits (178), Expect = 3e-12
Identities = 222/979 (22%), Positives = 289/979 (29%), Gaps = 197/979 (20%)
Query: 76 GAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133
G++ + G G G G PG E P L G GP PG G DG+
Sbjct: 35 GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGP-----------PGPRGQKGDDGIP 83
Query: 134 APPHSAAAALPPPAYGF-------GQP-YGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQ 185
PP PP GF G P + +P + G SPG LQ
Sbjct: 84 GPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQ 143
Query: 186 SGGGG-GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGS--- 241
G G+ G + P + N YP P L P G PG
Sbjct: 144 GPPGPPGIPGMKGEPGSIIMSSLPGPKGNP------GYPGPPGIQGLPGPTG-IPGPIGP 196
Query: 242 -GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300
G G PP + +F + G G G G P P + +
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPK-GEKGEQGLQ----GPPGPPGQISEQKRPI 251
Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360
+G QG PG GP +GP G + +
Sbjct: 252 DVEFQKGDQGLPG---DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308
Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420
P PG G G P P Q G P G G G + G PG
Sbjct: 309 PGIPGLPGDPGYP--GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366
Query: 421 PY--------GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472
P G Q P P G + + G +GP G G P +
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLD 425
Query: 473 QQSPHPQQQQPPYSQQP--PSQTPHAQPSYQQQPQSQPPQ-LQSSQ-------------- 515
Q P PP P P +P P S + LQ Q
Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCI 485
Query: 516 -PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA-PSTL 573
S P QP P P S Q+ + Q + P+ P P P P +
Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGL-PGIPGAPGAPGFPGSK 544
Query: 574 SQQA---AYPQPQSQQSQQTAYSQQRFPP-PQELSQDSFGSQASSAPSMTSSKGGQEDMN 629
+ +P + + + + P P QD P + KG +
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL-------PGLPGPKGEPGGIT 597
Query: 630 LSLQSRPSSLPDLSGSIDDL-PMGTEGALSPG-VSTSGISSSQGEQSNPAQ--------S 679
+ P P L G ++ PMG G PG V GI QG NP Q
Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI---QGVAGNPGQPGIPGPKGD 654
Query: 680 PFSPHTSPHLPGIRGPS-----------------------PSPVGSPASVAQSRSGPLSP 716
P T P PG+ G P G P GP P
Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP 714
Query: 717 AAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPR 774
PG PP P R ++ P P + P +PG AL P
Sbjct: 715 KGFPGIPGPPGAPG----------------TPGRIGLEGPPGPPGFPGPKGEPGFAL-PG 757
Query: 775 QPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGI 832
P G+ ++ G+ GP+G G GP G P + + LP G G +
Sbjct: 758 PPGP----PGLPGFK----GALGPKGDRGFPGPPGP-PGRTGLDGLP-------GPKGDV 801
Query: 833 NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGS-GMCPPPGGMN 891
P G G M G PG+P G P P +P +G G+ PG
Sbjct: 802 GPNGQPGPM-GPPGLPGIGVQGP--------------PGPPGIPGPIGQPGLHGIPG--- 843
Query: 892 RKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMG 951
+ PG P G+ GPP +G + G P GPP S G
Sbjct: 844 -----------------EKGDPGPP-----GLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881
Query: 952 GTMANNSAGMAASPEMMGL 970
++G + MG+
Sbjct: 882 LPGKAGASGFPGTKGEMGM 900
Score = 65.9 bits (159), Expect = 4e-10
Identities = 234/1043 (22%), Positives = 312/1043 (29%), Gaps = 218/1043 (20%)
Query: 5 VAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVG 64
+ P L PP PP K G E+GE Q +GP G
Sbjct: 194 IGPPGPPGLMGPPGPPGLPGPKGNM-------GLNFQGPKGEKGE------QGLQGPP-G 239
Query: 65 PP-------QPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAGPRPA 112
PP +P+ E Q G + G G G G G PG E K G G R
Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK 299
Query: 113 LNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172
PG G G+ P P Y G+P GR
Sbjct: 300 --------PGKDGENGQPGIPGLPGD-------PGYP-GEP-GRDGEKGQKGDT------ 336
Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYP--PPAPAYA 230
G PGL + G G + G + N G P + +P P P P A
Sbjct: 337 -GPPGPPGLVIPRPGTGITI----GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391
Query: 231 LSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG------ 284
+ P G G G + PP S + GA G GP G
Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG----QPGAPGLPGPPGPAGPHIPPS 447
Query: 285 ------GTPQPTATPTLNQLLTSPSSARGYQGYP-----GGDYSGGPQDGGAGKGPADMA 333
G P P +P ++ L +G +G G SG P G P
Sbjct: 448 DEICEPGPPGPPGSPG-DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506
Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393
S + A A+G P PG+ G G P ++ +P + G +
Sbjct: 507 SLGFPGQKGEKGQAGATG-----PKGLPGIPGAPGAPGFPGSKG-EPGDILTFPGMKGDK 560
Query: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453
G+ G P P Q G PG P P+ P + + + G +P
Sbjct: 561 GELGSPGAPGLPGLPGTPGQD-GLPGLP----GPKGEPGGITFKGERGPPGNPGLPGLPG 615
Query: 454 -YGQQGPSGYGQQGQTPYYNQQ--SPHPQQQQPPYSQQPPSQ--TPHAQPSYQQQPQSQP 508
G GP G+G G Q + +P Q P + P Q T +P P
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675
Query: 509 PQLQSSQPPYSQQPSQP--PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ 566
P QP P P + P P+ P P
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG---------- 725
Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626
AP T + P FP P+ G+
Sbjct: 726 --APGTPGRIGLEGPP----------GPPGFPGPK----------------------GEP 751
Query: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG-----VSTSGISSSQGEQS-NPAQSP 680
L P LP G++ P G G P G+ +G+ N P
Sbjct: 752 GFALPGPPGPPGLPGFKGALG--PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809
Query: 681 FSPHTSPHLPGI--RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH 738
P P LPGI +GP P P G P + Q +PG + P PP
Sbjct: 810 MGP---PGLPGIGVQGP-PGPPGIPGPIGQP-----GLHGIPGEKGDPGPPG-------- 852
Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPRQPSGGQIHTGMGSYQQNSMGSY 796
++ +RG +P +P P PGS P + G MG
Sbjct: 853 --LDVPGPPGERG----SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE-----MGMM 901
Query: 797 GPQGGQYGPQGGYPRQPNYNALPNANYPSA--GMAGGINPMGAGGQMHGQPGIPPYGTLP 854
GP G GP G P + +P G G P G G G+PG+P P
Sbjct: 902 GPPGPP-GPLG----IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK-GEPGLPG----P 951
Query: 855 PGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRP-- 912
PG P PN+ + G P G++ Q P
Sbjct: 952 PG----------PMDPNLLGSKGEKGEPGLPGIPGVS------------GPKGYQGLPGD 989
Query: 913 PGYPNMN-QGGMMGT-GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
PG P ++ Q G+ G GP G+ G+I P G ++G G+ P G+
Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049
Query: 971 GDVKLTPATKMNNKADGTPKTES 993
+P G P S
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISS 1072
Score = 36.2 bits (82), Expect = 0.34
Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 7/127 (5%)
Query: 53 AAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPR 110
+AG E E +GPP P G G G G G G PG + P + G GP
Sbjct: 1346 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1405
Query: 111 ----PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF-GQPYGRSPSAVAAAA 165
N L G GG G+ P + PP G G P S+VA
Sbjct: 1406 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGF 1465
Query: 166 AAVFHQQ 172
H Q
Sbjct: 1466 LITRHSQ 1472
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 102 bits (255), Expect = 3e-21
Identities = 224/949 (23%), Positives = 332/949 (34%), Gaps = 184/949 (19%)
Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
G +G+ PP P P Q GR P ++ QQ P Q
Sbjct: 201 GKPEGIIKPPLQQQPPKPIPKQ---QGPGRDPLQQDGTPKSISSQQ------PEKIKSQP 251
Query: 187 GGGGGLEPYAGPQQNSH-DHGFPNHQYNSYYPNRS--------AYPPPAPAYALSSPRGG 237
G G +P GP Q DH Q ++ P + P P+ + +
Sbjct: 252 PGTG--KPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 238 TPGSGAAAAAG---SKPPPSSS-ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293
TPG A G S+P P+ A S + AQQ G P GT +P A P
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKPPAQP 365
Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA 353
P+ P +G + GP A A A
Sbjct: 366 L------GPAK-------PPAQQTGSEKPSSEQPGPK----------ALAQPPGVGKTPA 402
Query: 354 QQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQ 413
QQ P P G +PLA+ P SP G T QQ GP P Q
Sbjct: 403 QQPGPAKP--PTQQVGTPKPLAQQPGLQSPAKAPGP--------TKTPVQQPGPGKIPAQ 452
Query: 414 GHGYPGQPYGSQT-PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472
G PG+ QT P + P + G A+ PP Q GP+ + P
Sbjct: 453 QAG-PGKTSAQQTGPTKPPSQLPGPAK------------PPPQQPGPA------KPPPQQ 493
Query: 473 QQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQ-SSQPPYSQQPS--QPPHQQ 529
S P QQP ++ PP Q A+PS QQ ++PP Q S P +QQPS +P QQ
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Query: 530 SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ---- 585
S P S T QPP P A+ P Q P+ P + + P+
Sbjct: 554 STKPV----SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609
Query: 586 --QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLS 643
+ Q T S F P P +T K E + L+ Q + + L
Sbjct: 610 CTECQTTVCSLCGFNPN---------------PHLTEVK---EWLCLNCQMKRA----LG 647
Query: 644 GSIDDLPMGTEGAL--SPGVSTSGISSS--QGEQSNPAQSP-----FSPHTSPHLPGIRG 694
G + +P + L +P +TS +S S Q +Q++P + S P P
Sbjct: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 695 PSPSPVGSPASVAQS--RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752
P+ GSP++ A+ + LS A PP+ PS S+ +++ +A D+
Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPA------PPKEPSVPSEQ------DKAPVADDK-- 753
Query: 753 MQRNPQMPQYSSPQPGSALSPRQPS--GGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYP 810
+ P+M + ++ S+ + +P ++ + + + + Q P G
Sbjct: 754 -PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK 812
Query: 811 RQP-NYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYG 869
P + A+P A + I+ G + GQ + P + + M +P
Sbjct: 813 VSPFDSKAIPRP----ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 870 ---PNMANMPP--QVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM 924
P + PP + +G P + K QE + + SI + P P Q +
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928
Query: 925 GTGPPYGQGINSMAGMI-----------------------NPQGPPYSMGGTMANNSAGM 961
G +G I S A + P PP S G + A
Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP 988
Query: 962 AASPEMMGLGDVKLTPATKMNNKADGTP---KTESKSK----KSSSSTT 1003
A + + + K A K+ KA+ P +TE++ K K S S T
Sbjct: 989 APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037
Score = 82.8 bits (203), Expect = 3e-15
Identities = 139/588 (23%), Positives = 196/588 (33%), Gaps = 88/588 (14%)
Query: 338 GAAAAAAAAAAASGGAQ---------------QRSHHAPMSPGSSGGGGQPLARTPQPSS 382
G AAAAAA ASG Q S + Q L + P +
Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPA 74
Query: 383 PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQ----RYPMTMQGRA 438
+ R Q ++P Q PP G P QP S++ R + GR+
Sbjct: 75 AAESPSMHRKQELDSSHPPKQSGRPPDP-----GRPAQPGLSKSRTTDTFRSEQKLPGRS 129
Query: 439 QSAMG---GLSYTQQIPPYGQQGPSGYGQQ-----GQTPYYNQQSPHPQQQQPPYSQQPP 490
S + S T + G+ + + N+ +P SQ+
Sbjct: 130 PSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET 189
Query: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP-PHQQSPAPYPSQQ-----STTQQH 544
++ Q +P+ +PP QQP +P P QQ P P QQ S + Q
Sbjct: 190 TKKQKVVQKEQGKPEG------IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243
Query: 545 PQ---SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601
P+ SQPP + Q P Q Q A L + A+ PQ + + + P P
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDH-AKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302
Query: 602 E--LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD--LPMGTE--- 654
+ + Q + G + P S+ G L G++ P GT
Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP 362
Query: 655 ----GALSPGVSTSGISSSQGEQSNP---AQSPFSPHTSPHLPGIRGPSPSPVGSPASVA 707
G P +G EQ P AQ P T PG P VG+P +A
Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422
Query: 708 QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP-- 765
Q + G SPA PG P G + + AQ G + Q+P + P
Sbjct: 423 Q-QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Query: 766 -QPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNY--------- 815
QPG A P Q G GS P Q GP P+QP
Sbjct: 482 QQPGPAKPPPQ------QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
Query: 816 NALPNANYPSAGMAGG------INPMGAGGQMHGQPGIPPYGTLPPGR 857
+A P+A PS ++ G+G + P + P PP +
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ-PPTVSPSAKQPPSQ 582
Score = 82.4 bits (202), Expect = 4e-15
Identities = 293/1403 (20%), Positives = 453/1403 (32%), Gaps = 267/1403 (19%)
Query: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPA--PYPSQQSTT 541
P PP+ +Q+ S P QS +PP +P+QP +S + S+Q
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 542 QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601
+ P S + ++++ +++ P LS+ A S ++ P
Sbjct: 127 GRSP-STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN---------PF 176
Query: 602 ELSQDSFGSQ--ASSAPSMTSSKGGQEDMNLS---LQSRPSSLPDLSGSIDDLPMGTEGA 656
+L DS SQ + + + G+ + + Q P +P G D P+ +G
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRD-PLQQDG- 234
Query: 657 LSPGVSTSGISSSQGEQ------------SNPAQSPFSPHTSPHL--------------- 689
+ ISS Q E+ P Q+P + H L
Sbjct: 235 -----TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV 289
Query: 690 ------PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743
P + PS P+ P P + PG PP PSG +
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT---------- 339
Query: 744 SSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG--PQGG 801
+AQ G ++ Q P + P P L P +P Q + S +Q + P G
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLP-----PG 856
+ Q P +P + P A G +P A G P G +P PG
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPK-PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 857 RMSHASMG-NRPYG--PNMANMPPQVGSGMCPP---PGGMNRKTQETAVAMHVAANSIQN 910
+ S G +P P A PPQ PP PG +Q+ Q
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP----QQ 513
Query: 911 RPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP-EMMG 969
P P+ Q G T PP Q P + + A SA + P G
Sbjct: 514 PGPAKPSPQQPG--STKPPSQQ---------PGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 970 LGDVKLTPATKMNNK---ADGTPKTESK-----------SKKSSSSTTTNEKITKLYELG 1015
G P + K + G PKT +K++ +T T + T G
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 1016 GEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRE 1075
P + TE K N + +GG + +
Sbjct: 623 FNPNPHL--------TEVKEWLCLNCQ--------------MKRALGGDLAPVPSSPQPK 660
Query: 1076 LATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSP 1135
L T TS+ + SS + Q + ++ P D+ A + KK P ++ P+
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQ--------QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 1136 AGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ--------IPPLPGMSRSNSVGI 1187
GS S + Q P++ S S PP S P Q P P M + + +
Sbjct: 713 HGSPSAKAKQPPEADSLSKP-----APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
Query: 1188 QDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKD---PYGSMR-KAPGSD 1243
+ + P + T S+ P + P+ S P SD
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 1244 PFMSSGQGPNG-----GMGDPYSRAAGPGLGNVAMGPR---QHYPYGGPYDRVRTEPGIG 1295
+ S GP+ DP + P M P+ + P G P T PG
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-----TPPGPR 882
Query: 1296 PEGNMSTGAPQPNLMPS--------NPDSGMYSPSRYPPQQQQQQQQRHDSYG----NQF 1343
P + PQ + P N S +P P Q+ + +G +Q
Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQA 942
Query: 1344 STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1403
S + +G P P Q S P PM+ +PS+ P K PP
Sbjct: 943 SNLISTAGQPGPHSQ----------SGPG---APMKQAPAPSQPPTSQGPPKSTGQAPPA 989
Query: 1404 PASHI-------APAPVQ-PPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRV 1455
PA I APA + P + T E P +K + LT + P+ +
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE----PQKAVL 1045
Query: 1456 MMSLKSGLLAESTWAL--DTINILLYDDNSIMT-----------FNLSQLPGLLELLVEY 1502
L+ EST L +NI D + T + P L E+
Sbjct: 1046 PTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWL 1105
Query: 1503 FRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGP---KLEEE 1559
C + G G + P +SP P+ ++ P KL ++
Sbjct: 1106 CLNCQTQ------RAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 1560 EEEEV--------VENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPF----- 1606
+E+EV +E +E K P +++ SK +K +Q+ P
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 1607 ------VVDCSDKLGRVQE-----FDSGLL-HWRIGGGDTTEH--IQTHFESKTELLPSR 1652
+ +K ++E D LL + + +H +++ + E L R
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279
Query: 1653 PHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRI--------TATMDDMLSTRSST 1704
++ T EG P T Q P D K I TA D + + T
Sbjct: 1280 VAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKT 1339
Query: 1705 LTEDGAKSSEAIKESSKFPFGIS 1727
ED KS + + K P G+S
Sbjct: 1340 EKEDD-KSDTSSSQQPKSPQGLS 1361
Score = 81.3 bits (199), Expect = 9e-15
Identities = 106/418 (25%), Positives = 146/418 (34%), Gaps = 61/418 (14%)
Query: 389 KMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448
K + +P G P QQQ P P+Q Q P R P+ G +S +
Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQ-----------QGPGRDPLQQDGTPKSI------S 240
Query: 449 QQIPPYGQQGPSGYGQQGQTPYYNQQSPH-----------PQQQQPPY---SQQPPSQTP 494
Q P + P G G+ Q P Q+ H PQ +Q PS
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300
Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP-SQQSTTQQHPQSQPPYSQ 553
++P QQ +PP Q P++PP Q S P +QQ T + P P ++
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 554 PQAQ------SPYQQ---QQP--QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602
P AQ P QQ ++P +QP P L+Q + +QQ Q+ P+
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
L+Q + AP T + Q P +P G P
Sbjct: 421 LAQQPGLQSPAKAPGPTKTP--------VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 663 TSGISSSQGEQSNPA----QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA 718
G + +Q PA Q P S PG P P G PA + + G P
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGSTKP-- 529
Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSS--IAQDRGYMQRNPQMPQYSSPQPGSALSPR 774
P Q PS Q S PS QS+ ++Q P S+ QP S P+
Sbjct: 530 -PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Score = 60.5 bits (145), Expect = 2e-08
Identities = 170/816 (20%), Positives = 268/816 (32%), Gaps = 151/816 (18%)
Query: 12 SLGNPPPPP---PSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQE--SEGPAVGPP 66
SL +P PP P+ K QQ E A A+ + Q+ + P V PP
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356
Query: 67 -------QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTE 119
QPLG ++ G+E K S+ GP+ L +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQT---------------GSE---KPSSEQPGPKA-----LAQ 393
Query: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG--QPYGRSPSAVAAAAAAVFHQQHGGQQ 177
PPG VG P PP G +P + P + A A + Q
Sbjct: 394 PPG---------VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 178 SPG-LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG 236
PG + A Q+G G GP + S P + PP P A P+
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPP-----------SQLPGPAKPPPQQPGPAKPPPQ- 492
Query: 237 GTPGSG---AAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293
PGS + +KPPP A S + + P +A QP+
Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ---QPGSAKPSAQQPSPAK 548
Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGP---QDGGAGKGPADMASQC-------------- 336
Q T P S G G P + P Q G P + C
Sbjct: 549 PSAQQSTKPVSQTG-SGKPLQPPTVSPSAKQPPSQGL-PKTICPLCNTTELLLHVPEKAN 606
Query: 337 WGAAAAAAAAAAASGGAQQRSHHAPMS---------PGSSGGGGQPLARTPQPS------ 381
+ + G H + + GG P+ +PQP
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666
Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQG--- 436
+ + K PQP QQ P + P+Q +P + P T+ G
Sbjct: 667 TTTSAVSKSSPQP--------QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP-TLHGSPS 717
Query: 437 -RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP------PYSQQP 489
+A+ S ++ PP + PS +Q + P + + P+ +P S
Sbjct: 718 AKAKQPPEADSLSKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 490 PSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPS---QPPHQQSPAPYPSQQSTTQQHP 545
P ++ Q + ++ PP + S++P S P+ P P P+ S HP
Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Query: 546 -QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ--------QTAYSQQR 596
S Q Q ++++P++ + A P P+ + QT + Q+
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894
Query: 597 FPPPQELSQD---SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGT 653
P PQE S+ + GS + S ++ QE + L +S+ + ++ + T
Sbjct: 895 SPKPQEQSRRFSLNLGSITDAPKSQPTTP--QETVTGKLFGFGASIFSQASNL----IST 948
Query: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713
G PG + S G A +P P TS P G +P V + P
Sbjct: 949 AG--QPGPHS---QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749
+ P + P +++ P + S+ +
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 44.3 bits (103), Expect = 0.001
Identities = 47/170 (27%), Positives = 61/170 (35%), Gaps = 30/170 (17%)
Query: 408 PSGPQQGHGYPGQPYGSQTP--QRYPMTMQGRAQSAMGGLSYTQ---QIPPYGQQGPSGY 462
P+ + HG QT Q P Q +Q YTQ P Q P+ Y
Sbjct: 3844 PTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSY 3903
Query: 463 GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522
QQ ++ QQ+ + QQ P YQ QP Q S P P
Sbjct: 3904 TQQS---HFEQQTLYHQQVSP----------------YQTQPTFQAVATMSFTPQVQPTP 3944
Query: 523 SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ--QQQPQQPAP 570
+ P Q PSQ QQ P+ Y +P+ S Y+ + QP AP
Sbjct: 3945 TPQPSYQ----LPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAP 3990
Score = 41.2 bits (95), Expect = 0.011
Identities = 57/254 (22%), Positives = 90/254 (35%), Gaps = 26/254 (10%)
Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546
++P SQ P PS P P +SS S QP PP P P P P
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---------PP 2420
Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS-QQTAYSQQRFPPPQEL-- 603
PP P SP P++ A P + + + TA + P +
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480
Query: 604 -SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRP--SSLPDLSGSIDDL-PMGTEGALSP 659
+ + SS PS E + +P LP + D+ P T +L+
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540
Query: 660 GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG---------PSPSPVGSPASVAQSR 710
++ + ++S+ + +P SP SPH++ P PS G+P + S+
Sbjct: 2541 SMTLNLVTSADYKLPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599
Query: 711 SGPLSPAAVPGNQM 724
+ P P +
Sbjct: 2600 AITSWPLGSPSKDL 2613
Score = 40.8 bits (94), Expect = 0.014
Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 25/234 (10%)
Query: 364 PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG 423
P S G + + + P KM P+P P P P G P
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP----- 890
Query: 424 SQTPQRYPMTMQGRAQSAMGGLSYT---QQIPPYGQQGPSGYGQQGQTPYYNQQSP--HP 478
TPQ+ P + + ++ S T + P Q+ +G ++Q S
Sbjct: 891 --TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948
Query: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ- 537
Q P+SQ P P+ Q P SQ P + Q P + S P +++ AP +
Sbjct: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008
Query: 538 QSTTQQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584
+ +Q P + +PP P S +PQ+ T +++ P+P+S
Sbjct: 1009 EPKAEQAPTVKRTETEKKPP---PIKDSKSLTAEPQKAVLPTKLEKS--PKPES 1057
Score = 38.5 bits (88), Expect = 0.069
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 475 SPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPSQPPHQQSPAP 533
S P + + + + P P + S PQ+Q QL PY+Q P + AP
Sbjct: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900
Query: 534 YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLS-----QQAAYPQPQSQQSQ 588
T Q H + Q Y Q SPY Q QP A +T+S Q PQP Q
Sbjct: 3901 ---TSYTQQSHFEQQTLYHQQV--SPY-QTQPTFQAVATMSFTPQVQPTPTPQPSYQLPS 3954
Query: 589 QTAYSQQR 596
Q QQ+
Sbjct: 3955 QMMVIQQK 3962
Score = 38.1 bits (87), Expect = 0.090
Identities = 69/282 (24%), Positives = 113/282 (40%), Gaps = 41/282 (14%)
Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQP 554
HA SY+ P+S+ + S+ +Q ++ Q PA Q+ + + P S+
Sbjct: 4150 HADTSYRHFPKSEKYSI--SRLTLEKQAAK----QLPAAILYQKQSKHKKSLIDPKMSK- 4202
Query: 555 QAQSPYQQQQPQQP------APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608
SP Q+ + +P ST S + + Q T ++ Q+ S
Sbjct: 4203 --FSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260
Query: 609 GSQASS-APSMTSSKGGQEDMNLSL--QSRPSSLP------DLS----GSIDDLPMGTEG 655
G+ + ++ S+ + D S +SRPSS P DLS S L + +
Sbjct: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320
Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP-----SPVGSPASVAQSR 710
A + VS S SSS ++ P P S + +P + S SPVG P +A++
Sbjct: 4321 AEALDVSFSHASSSA--RTKPTSLPIS-QSRGRIPIVAQNSEEESPLSPVGQPMGMARAA 4377
Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752
+GPL P + R G S S+ + ++ RGY
Sbjct: 4378 AGPLPPISA-----DTRDQFGSSHSLPEVQQHMREESRTRGY 4414
Score = 35.0 bits (79), Expect = 0.76
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 6/98 (6%)
Query: 520 QQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY 579
++P P + P Q T Q PY+Q Q SP Q AP++ +QQ+ +
Sbjct: 3854 ERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQ----APTSYTQQSHF 3909
Query: 580 PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPS 617
Q Q + Y Q P Q ++ SF Q P+
Sbjct: 3910 EQQTLYHQQVSPYQTQ--PTFQAVATMSFTPQVQPTPT 3945
Score = 32.7 bits (73), Expect = 3.8
Identities = 26/127 (20%), Positives = 50/127 (39%), Gaps = 2/127 (1%)
Query: 1284 PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQF 1343
P DR R E + T P + S + SPS + +QQ++ RH +G
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLL 1767
Query: 1344 STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1403
T S ++ + ++Q++ R ++ S L + + ++ P
Sbjct: 1768 PTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRER--PKT 1825
Query: 1404 PASHIAP 1410
P S+++P
Sbjct: 1826 PPSNLSP 1832
Score = 32.0 bits (71), Expect = 6.4
Identities = 42/188 (22%), Positives = 70/188 (37%), Gaps = 24/188 (12%)
Query: 469 PYYNQQSPHPQQQQ--PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526
P ++ P P+ ++ P P + H + Q Q +L+ P + Q + P
Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEEQKH--DLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291
Query: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQ 586
+ + PQS P ++ +Q QP A + +
Sbjct: 1292 QTK-------MEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDD 1344
Query: 587 SQQTAYSQQRFPPPQELSQDSFGSQASSA-----PSMTSS------KGGQEDMNLSLQSR 635
T+ SQQ PQ LS + S S+ PS+ + KG ++D + S +S
Sbjct: 1345 KSDTSSSQQP-KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD-SFSQESS 1402
Query: 636 PSSLPDLS 643
PSS DL+
Sbjct: 1403 PSSPSDLA 1410
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 102 bits (255), Expect = 3e-21
Identities = 224/949 (23%), Positives = 332/949 (34%), Gaps = 184/949 (19%)
Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
G +G+ PP P P Q GR P ++ QQ P Q
Sbjct: 201 GKPEGIIKPPLQQQPPKPIPKQ---QGPGRDPLQQDGTPKSISSQQ------PEKIKSQP 251
Query: 187 GGGGGLEPYAGPQQNSH-DHGFPNHQYNSYYPNRS--------AYPPPAPAYALSSPRGG 237
G G +P GP Q DH Q ++ P + P P+ + +
Sbjct: 252 PGTG--KPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 238 TPGSGAAAAAG---SKPPPSSS-ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293
TPG A G S+P P+ A S + AQQ G P GT +P A P
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKPPAQP 365
Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA 353
P+ P +G + GP A A A
Sbjct: 366 L------GPAK-------PPAQQTGSEKPSSEQPGPK----------ALAQPPGVGKTPA 402
Query: 354 QQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQ 413
QQ P P G +PLA+ P SP G T QQ GP P Q
Sbjct: 403 QQPGPAKP--PTQQVGTPKPLAQQPGLQSPAKAPGP--------TKTPVQQPGPGKIPAQ 452
Query: 414 GHGYPGQPYGSQT-PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472
G PG+ QT P + P + G A+ PP Q GP+ + P
Sbjct: 453 QAG-PGKTSAQQTGPTKPPSQLPGPAK------------PPPQQPGPA------KPPPQQ 493
Query: 473 QQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQ-SSQPPYSQQPS--QPPHQQ 529
S P QQP ++ PP Q A+PS QQ ++PP Q S P +QQPS +P QQ
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Query: 530 SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ---- 585
S P S T QPP P A+ P Q P+ P + + P+
Sbjct: 554 STKPV----SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609
Query: 586 --QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLS 643
+ Q T S F P P +T K E + L+ Q + + L
Sbjct: 610 CTECQTTVCSLCGFNPN---------------PHLTEVK---EWLCLNCQMKRA----LG 647
Query: 644 GSIDDLPMGTEGAL--SPGVSTSGISSS--QGEQSNPAQSP-----FSPHTSPHLPGIRG 694
G + +P + L +P +TS +S S Q +Q++P + S P P
Sbjct: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 695 PSPSPVGSPASVAQS--RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752
P+ GSP++ A+ + LS A PP+ PS S+ +++ +A D+
Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPA------PPKEPSVPSEQ------DKAPVADDK-- 753
Query: 753 MQRNPQMPQYSSPQPGSALSPRQPS--GGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYP 810
+ P+M + ++ S+ + +P ++ + + + + Q P G
Sbjct: 754 -PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK 812
Query: 811 RQP-NYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYG 869
P + A+P A + I+ G + GQ + P + + M +P
Sbjct: 813 VSPFDSKAIPRP----ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 870 ---PNMANMPP--QVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM 924
P + PP + +G P + K QE + + SI + P P Q +
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928
Query: 925 GTGPPYGQGINSMAGMI-----------------------NPQGPPYSMGGTMANNSAGM 961
G +G I S A + P PP S G + A
Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP 988
Query: 962 AASPEMMGLGDVKLTPATKMNNKADGTP---KTESKSK----KSSSSTT 1003
A + + + K A K+ KA+ P +TE++ K K S S T
Sbjct: 989 APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037
Score = 82.8 bits (203), Expect = 3e-15
Identities = 139/588 (23%), Positives = 196/588 (33%), Gaps = 88/588 (14%)
Query: 338 GAAAAAAAAAAASGGAQ---------------QRSHHAPMSPGSSGGGGQPLARTPQPSS 382
G AAAAAA ASG Q S + Q L + P +
Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPA 74
Query: 383 PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQ----RYPMTMQGRA 438
+ R Q ++P Q PP G P QP S++ R + GR+
Sbjct: 75 AAESPSMHRKQELDSSHPPKQSGRPPDP-----GRPAQPGLSKSRTTDTFRSEQKLPGRS 129
Query: 439 QSAMG---GLSYTQQIPPYGQQGPSGYGQQ-----GQTPYYNQQSPHPQQQQPPYSQQPP 490
S + S T + G+ + + N+ +P SQ+
Sbjct: 130 PSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET 189
Query: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP-PHQQSPAPYPSQQ-----STTQQH 544
++ Q +P+ +PP QQP +P P QQ P P QQ S + Q
Sbjct: 190 TKKQKVVQKEQGKPEG------IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243
Query: 545 PQ---SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601
P+ SQPP + Q P Q Q A L + A+ PQ + + + P P
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDH-AKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302
Query: 602 E--LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD--LPMGTE--- 654
+ + Q + G + P S+ G L G++ P GT
Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP 362
Query: 655 ----GALSPGVSTSGISSSQGEQSNP---AQSPFSPHTSPHLPGIRGPSPSPVGSPASVA 707
G P +G EQ P AQ P T PG P VG+P +A
Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422
Query: 708 QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP-- 765
Q + G SPA PG P G + + AQ G + Q+P + P
Sbjct: 423 Q-QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Query: 766 -QPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNY--------- 815
QPG A P Q G GS P Q GP P+QP
Sbjct: 482 QQPGPAKPPPQ------QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
Query: 816 NALPNANYPSAGMAGG------INPMGAGGQMHGQPGIPPYGTLPPGR 857
+A P+A PS ++ G+G + P + P PP +
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ-PPTVSPSAKQPPSQ 582
Score = 82.4 bits (202), Expect = 4e-15
Identities = 293/1403 (20%), Positives = 453/1403 (32%), Gaps = 267/1403 (19%)
Query: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPA--PYPSQQSTT 541
P PP+ +Q+ S P QS +PP +P+QP +S + S+Q
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 542 QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601
+ P S + ++++ +++ P LS+ A S ++ P
Sbjct: 127 GRSP-STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN---------PF 176
Query: 602 ELSQDSFGSQ--ASSAPSMTSSKGGQEDMNLS---LQSRPSSLPDLSGSIDDLPMGTEGA 656
+L DS SQ + + + G+ + + Q P +P G D P+ +G
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRD-PLQQDG- 234
Query: 657 LSPGVSTSGISSSQGEQ------------SNPAQSPFSPHTSPHL--------------- 689
+ ISS Q E+ P Q+P + H L
Sbjct: 235 -----TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV 289
Query: 690 ------PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743
P + PS P+ P P + PG PP PSG +
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT---------- 339
Query: 744 SSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG--PQGG 801
+AQ G ++ Q P + P P L P +P Q + S +Q + P G
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLP-----PG 856
+ Q P +P + P A G +P A G P G +P PG
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPK-PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 857 RMSHASMG-NRPYG--PNMANMPPQVGSGMCPP---PGGMNRKTQETAVAMHVAANSIQN 910
+ S G +P P A PPQ PP PG +Q+ Q
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP----QQ 513
Query: 911 RPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP-EMMG 969
P P+ Q G T PP Q P + + A SA + P G
Sbjct: 514 PGPAKPSPQQPG--STKPPSQQ---------PGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 970 LGDVKLTPATKMNNK---ADGTPKTESK-----------SKKSSSSTTTNEKITKLYELG 1015
G P + K + G PKT +K++ +T T + T G
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 1016 GEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRE 1075
P + TE K N + +GG + +
Sbjct: 623 FNPNPHL--------TEVKEWLCLNCQ--------------MKRALGGDLAPVPSSPQPK 660
Query: 1076 LATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSP 1135
L T TS+ + SS + Q + ++ P D+ A + KK P ++ P+
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQ--------QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 1136 AGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ--------IPPLPGMSRSNSVGI 1187
GS S + Q P++ S S PP S P Q P P M + + +
Sbjct: 713 HGSPSAKAKQPPEADSLSKP-----APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
Query: 1188 QDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKD---PYGSMR-KAPGSD 1243
+ + P + T S+ P + P+ S P SD
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 1244 PFMSSGQGPNG-----GMGDPYSRAAGPGLGNVAMGPR---QHYPYGGPYDRVRTEPGIG 1295
+ S GP+ DP + P M P+ + P G P T PG
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-----TPPGPR 882
Query: 1296 PEGNMSTGAPQPNLMPS--------NPDSGMYSPSRYPPQQQQQQQQRHDSYG----NQF 1343
P + PQ + P N S +P P Q+ + +G +Q
Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQA 942
Query: 1344 STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1403
S + +G P P Q S P PM+ +PS+ P K PP
Sbjct: 943 SNLISTAGQPGPHSQ----------SGPG---APMKQAPAPSQPPTSQGPPKSTGQAPPA 989
Query: 1404 PASHI-------APAPVQ-PPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRV 1455
PA I APA + P + T E P +K + LT + P+ +
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE----PQKAVL 1045
Query: 1456 MMSLKSGLLAESTWAL--DTINILLYDDNSIMT-----------FNLSQLPGLLELLVEY 1502
L+ EST L +NI D + T + P L E+
Sbjct: 1046 PTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWL 1105
Query: 1503 FRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGP---KLEEE 1559
C + G G + P +SP P+ ++ P KL ++
Sbjct: 1106 CLNCQTQ------RAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 1560 EEEEV--------VENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPF----- 1606
+E+EV +E +E K P +++ SK +K +Q+ P
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 1607 ------VVDCSDKLGRVQE-----FDSGLL-HWRIGGGDTTEH--IQTHFESKTELLPSR 1652
+ +K ++E D LL + + +H +++ + E L R
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279
Query: 1653 PHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRI--------TATMDDMLSTRSST 1704
++ T EG P T Q P D K I TA D + + T
Sbjct: 1280 VAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKT 1339
Query: 1705 LTEDGAKSSEAIKESSKFPFGIS 1727
ED KS + + K P G+S
Sbjct: 1340 EKEDD-KSDTSSSQQPKSPQGLS 1361
Score = 81.3 bits (199), Expect = 9e-15
Identities = 106/418 (25%), Positives = 146/418 (34%), Gaps = 61/418 (14%)
Query: 389 KMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448
K + +P G P QQQ P P+Q Q P R P+ G +S +
Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQ-----------QGPGRDPLQQDGTPKSI------S 240
Query: 449 QQIPPYGQQGPSGYGQQGQTPYYNQQSPH-----------PQQQQPPY---SQQPPSQTP 494
Q P + P G G+ Q P Q+ H PQ +Q PS
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300
Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP-SQQSTTQQHPQSQPPYSQ 553
++P QQ +PP Q P++PP Q S P +QQ T + P P ++
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 554 PQAQ------SPYQQ---QQP--QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602
P AQ P QQ ++P +QP P L+Q + +QQ Q+ P+
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
L+Q + AP T + Q P +P G P
Sbjct: 421 LAQQPGLQSPAKAPGPTKTP--------VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 663 TSGISSSQGEQSNPA----QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA 718
G + +Q PA Q P S PG P P G PA + + G P
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGSTKP-- 529
Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSS--IAQDRGYMQRNPQMPQYSSPQPGSALSPR 774
P Q PS Q S PS QS+ ++Q P S+ QP S P+
Sbjct: 530 -PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Score = 60.5 bits (145), Expect = 2e-08
Identities = 170/816 (20%), Positives = 268/816 (32%), Gaps = 151/816 (18%)
Query: 12 SLGNPPPPP---PSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQE--SEGPAVGPP 66
SL +P PP P+ K QQ E A A+ + Q+ + P V PP
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356
Query: 67 -------QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTE 119
QPLG ++ G+E K S+ GP+ L +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQT---------------GSE---KPSSEQPGPKA-----LAQ 393
Query: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG--QPYGRSPSAVAAAAAAVFHQQHGGQQ 177
PPG VG P PP G +P + P + A A + Q
Sbjct: 394 PPG---------VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 178 SPG-LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG 236
PG + A Q+G G GP + S P + PP P A P+
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPP-----------SQLPGPAKPPPQQPGPAKPPPQ- 492
Query: 237 GTPGSG---AAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293
PGS + +KPPP A S + + P +A QP+
Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ---QPGSAKPSAQQPSPAK 548
Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGP---QDGGAGKGPADMASQC-------------- 336
Q T P S G G P + P Q G P + C
Sbjct: 549 PSAQQSTKPVSQTG-SGKPLQPPTVSPSAKQPPSQGL-PKTICPLCNTTELLLHVPEKAN 606
Query: 337 WGAAAAAAAAAAASGGAQQRSHHAPMS---------PGSSGGGGQPLARTPQPS------ 381
+ + G H + + GG P+ +PQP
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666
Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQG--- 436
+ + K PQP QQ P + P+Q +P + P T+ G
Sbjct: 667 TTTSAVSKSSPQP--------QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP-TLHGSPS 717
Query: 437 -RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP------PYSQQP 489
+A+ S ++ PP + PS +Q + P + + P+ +P S
Sbjct: 718 AKAKQPPEADSLSKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 490 PSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPS---QPPHQQSPAPYPSQQSTTQQHP 545
P ++ Q + ++ PP + S++P S P+ P P P+ S HP
Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Query: 546 -QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ--------QTAYSQQR 596
S Q Q ++++P++ + A P P+ + QT + Q+
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894
Query: 597 FPPPQELSQD---SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGT 653
P PQE S+ + GS + S ++ QE + L +S+ + ++ + T
Sbjct: 895 SPKPQEQSRRFSLNLGSITDAPKSQPTTP--QETVTGKLFGFGASIFSQASNL----IST 948
Query: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713
G PG + S G A +P P TS P G +P V + P
Sbjct: 949 AG--QPGPHS---QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749
+ P + P +++ P + S+ +
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 44.3 bits (103), Expect = 0.001
Identities = 47/170 (27%), Positives = 61/170 (35%), Gaps = 30/170 (17%)
Query: 408 PSGPQQGHGYPGQPYGSQTP--QRYPMTMQGRAQSAMGGLSYTQ---QIPPYGQQGPSGY 462
P+ + HG QT Q P Q +Q YTQ P Q P+ Y
Sbjct: 3844 PTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSY 3903
Query: 463 GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522
QQ ++ QQ+ + QQ P YQ QP Q S P P
Sbjct: 3904 TQQS---HFEQQTLYHQQVSP----------------YQTQPTFQAVATMSFTPQVQPTP 3944
Query: 523 SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ--QQQPQQPAP 570
+ P Q PSQ QQ P+ Y +P+ S Y+ + QP AP
Sbjct: 3945 TPQPSYQ----LPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAP 3990
Score = 41.2 bits (95), Expect = 0.011
Identities = 57/254 (22%), Positives = 90/254 (35%), Gaps = 26/254 (10%)
Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546
++P SQ P PS P P +SS S QP PP P P P P
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---------PP 2420
Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS-QQTAYSQQRFPPPQEL-- 603
PP P SP P++ A P + + + TA + P +
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480
Query: 604 -SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRP--SSLPDLSGSIDDL-PMGTEGALSP 659
+ + SS PS E + +P LP + D+ P T +L+
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540
Query: 660 GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG---------PSPSPVGSPASVAQSR 710
++ + ++S+ + +P SP SPH++ P PS G+P + S+
Sbjct: 2541 SMTLNLVTSADYKLPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599
Query: 711 SGPLSPAAVPGNQM 724
+ P P +
Sbjct: 2600 AITSWPLGSPSKDL 2613
Score = 40.8 bits (94), Expect = 0.014
Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 25/234 (10%)
Query: 364 PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG 423
P S G + + + P KM P+P P P P G P
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP----- 890
Query: 424 SQTPQRYPMTMQGRAQSAMGGLSYT---QQIPPYGQQGPSGYGQQGQTPYYNQQSP--HP 478
TPQ+ P + + ++ S T + P Q+ +G ++Q S
Sbjct: 891 --TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948
Query: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ- 537
Q P+SQ P P+ Q P SQ P + Q P + S P +++ AP +
Sbjct: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008
Query: 538 QSTTQQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584
+ +Q P + +PP P S +PQ+ T +++ P+P+S
Sbjct: 1009 EPKAEQAPTVKRTETEKKPP---PIKDSKSLTAEPQKAVLPTKLEKS--PKPES 1057
Score = 38.5 bits (88), Expect = 0.069
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 475 SPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPSQPPHQQSPAP 533
S P + + + + P P + S PQ+Q QL PY+Q P + AP
Sbjct: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900
Query: 534 YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLS-----QQAAYPQPQSQQSQ 588
T Q H + Q Y Q SPY Q QP A +T+S Q PQP Q
Sbjct: 3901 ---TSYTQQSHFEQQTLYHQQV--SPY-QTQPTFQAVATMSFTPQVQPTPTPQPSYQLPS 3954
Query: 589 QTAYSQQR 596
Q QQ+
Sbjct: 3955 QMMVIQQK 3962
Score = 38.1 bits (87), Expect = 0.090
Identities = 69/282 (24%), Positives = 113/282 (40%), Gaps = 41/282 (14%)
Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQP 554
HA SY+ P+S+ + S+ +Q ++ Q PA Q+ + + P S+
Sbjct: 4150 HADTSYRHFPKSEKYSI--SRLTLEKQAAK----QLPAAILYQKQSKHKKSLIDPKMSK- 4202
Query: 555 QAQSPYQQQQPQQP------APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608
SP Q+ + +P ST S + + Q T ++ Q+ S
Sbjct: 4203 --FSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260
Query: 609 GSQASS-APSMTSSKGGQEDMNLSL--QSRPSSLP------DLS----GSIDDLPMGTEG 655
G+ + ++ S+ + D S +SRPSS P DLS S L + +
Sbjct: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320
Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP-----SPVGSPASVAQSR 710
A + VS S SSS ++ P P S + +P + S SPVG P +A++
Sbjct: 4321 AEALDVSFSHASSSA--RTKPTSLPIS-QSRGRIPIVAQNSEEESPLSPVGQPMGMARAA 4377
Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752
+GPL P + R G S S+ + ++ RGY
Sbjct: 4378 AGPLPPISA-----DTRDQFGSSHSLPEVQQHMREESRTRGY 4414
Score = 35.0 bits (79), Expect = 0.76
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 6/98 (6%)
Query: 520 QQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY 579
++P P + P Q T Q PY+Q Q SP Q AP++ +QQ+ +
Sbjct: 3854 ERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQ----APTSYTQQSHF 3909
Query: 580 PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPS 617
Q Q + Y Q P Q ++ SF Q P+
Sbjct: 3910 EQQTLYHQQVSPYQTQ--PTFQAVATMSFTPQVQPTPT 3945
Score = 32.7 bits (73), Expect = 3.8
Identities = 26/127 (20%), Positives = 50/127 (39%), Gaps = 2/127 (1%)
Query: 1284 PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQF 1343
P DR R E + T P + S + SPS + +QQ++ RH +G
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLL 1767
Query: 1344 STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1403
T S ++ + ++Q++ R ++ S L + + ++ P
Sbjct: 1768 PTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRER--PKT 1825
Query: 1404 PASHIAP 1410
P S+++P
Sbjct: 1826 PPSNLSP 1832
Score = 32.0 bits (71), Expect = 6.4
Identities = 42/188 (22%), Positives = 70/188 (37%), Gaps = 24/188 (12%)
Query: 469 PYYNQQSPHPQQQQ--PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526
P ++ P P+ ++ P P + H + Q Q +L+ P + Q + P
Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEEQKH--DLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291
Query: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQ 586
+ + PQS P ++ +Q QP A + +
Sbjct: 1292 QTK-------MEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDD 1344
Query: 587 SQQTAYSQQRFPPPQELSQDSFGSQASSA-----PSMTSS------KGGQEDMNLSLQSR 635
T+ SQQ PQ LS + S S+ PS+ + KG ++D + S +S
Sbjct: 1345 KSDTSSSQQP-KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD-SFSQESS 1402
Query: 636 PSSLPDLS 643
PSS DL+
Sbjct: 1403 PSSPSDLA 1410
>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein [Homo
sapiens]
Length = 593
Score = 102 bits (254), Expect = 4e-21
Identities = 66/194 (34%), Positives = 104/194 (53%), Gaps = 21/194 (10%)
Query: 1003 TTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIG 1062
T E+ +LYEL G+P+RK ++D +F +++ + +P + ++ LDL+ LYV V E G
Sbjct: 224 TYEEQFKQLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKG 283
Query: 1063 GLTQVNKNKKWRELATNLNVGTS-SSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAA 1121
GL +V K WRE+ LN+ TS +SAA +L+ QY++ LY +EC+ +RG P ++ AA
Sbjct: 284 GLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECE-KRGLSNPNELQAAI 342
Query: 1122 DSKKSQPKIQ-------PPSPAGS-GSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI 1173
DS + + + Q SP G+ G + P+ P S+ AST S I
Sbjct: 343 DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLG-----------LAASTNGSSI 391
Query: 1174 PPLPGMSRSNSVGI 1187
P P + + I
Sbjct: 392 TPAPKIKKEEDSAI 405
Score = 38.1 bits (87), Expect = 0.090
Identities = 45/197 (22%), Positives = 63/197 (31%), Gaps = 10/197 (5%)
Query: 15 NPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ--PLGKE 72
+PP PP + A + RE A A M+AAA + G + P G E
Sbjct: 30 DPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASPGGSEDGPPGSE 89
Query: 73 LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR---PALNNNLTEPPGGGGGGSS 129
+D A G G G G D+ S+ + P+ + +L E
Sbjct: 90 EEDAAREGTPGSPGRGREGPGEEHFEDMA-SDEDMKPKWEEEEMEEDLGEDEEEEEEDYE 148
Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
D P + G + R A + GGQ+ PG GG
Sbjct: 149 DEEEEEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGVPRVLGGQERPGPGPAHPGGA 208
Query: 190 GGLEPYAGPQQNSHDHG 206
+ PQ DHG
Sbjct: 209 A----HVAPQLQPPDHG 221
Score = 32.7 bits (73), Expect = 3.8
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 5/45 (11%)
Query: 65 PPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGP 109
PP P A + GGGGGGG+ S G G + S G AGP
Sbjct: 538 PPAPT----PTSAPNKGGGGGGGSSSNAG-GRGGNTGTSGGQAGP 577
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 102 bits (253), Expect = 5e-21
Identities = 244/1052 (23%), Positives = 312/1052 (29%), Gaps = 206/1052 (19%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERG-----EMKAAAGQESEGP 61
P + PP P K+ G A +RG + G E
Sbjct: 572 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 631
Query: 62 AVGPPQPLGKELQDGAESNGGGGG--GGAGSGG--GPGAEPDLKNSNGNAGPRPALNNNL 117
GPP P G + G + G G G AG G GP P G AG +
Sbjct: 632 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG--------V 683
Query: 118 TEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
PPG G G PP + LP P G P + P
Sbjct: 684 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP--------------- 728
Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF---PNHQYNSYYPNRSAYPPPAPAYA 230
Q PGLA L G G + G + S + G P Q YP
Sbjct: 729 --QGKPGLAGLP--GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 784
Query: 231 LSSPRG-----GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284
L +G G PG G G + + R G G GPS G
Sbjct: 785 LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 844
Query: 285 -----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK-GPADMASQCWG 338
G P P P + G+ G+PG + G + G AGK GP
Sbjct: 845 EKGKLGVPGLPGYPGRQ----GPKGSTGFPGFPGANGEKGAR-GVAGKPGPRGQRGPTGP 899
Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ-PYGG 397
+ A G + G+SGG G P P + G PQ P G
Sbjct: 900 RGSRGARGPTGKPGPK----------GTSGGDGPP--------GPPGERGPQGPQGPVGF 941
Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ-----SAMGGLSYTQQIP 452
P +GPP GP G PG P QR QG+ +G T +
Sbjct: 942 PGP----KGPP-GPPGKDGLPGHP-----GQRGETGFQGKTGPPGPGGVVGPQGPTGETG 991
Query: 453 PYGQQG----PSGYGQQGQTPYYNQQS----PHPQ----------------QQQPPYSQQ 488
P G++G P G+QG ++ P PQ ++ P +Q
Sbjct: 992 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1051
Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS-QQPSQPPHQQSPAPYPSQQSTTQQHPQS 547
P P P P + S+ P +P Q P P + + ++ PQ
Sbjct: 1052 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1111
Query: 548 QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDS 607
P + Q P P PA S + Q + PP Q
Sbjct: 1112 --PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1169
Query: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667
G+ + GQ+ M D+ G G P + G+
Sbjct: 1170 VGAPGIAGGDGEPGPRGQQGM-------------FGQKGDEGARGFPGPPGP-IGLQGLP 1215
Query: 668 SSQGEQS-NPAQSPFSPHTSPHLPGIRGP-----SPSPVGSPASVAQSRSGPLSPAAVPG 721
GE+ N P P P PG RGP + P G P SV G + PG
Sbjct: 1216 GPPGEKGENGDVGPMGP---PGPPGPRGPQGPNGADGPQGPPGSVGSV--GGVGEKGEPG 1270
Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM----QRNPQMPQYSSPQPGSALSPRQPS 777
P PP + A G + P PG P P
Sbjct: 1271 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1330
Query: 778 -------GGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGM 828
GQ G + G GP G G+ GP G P P A AG
Sbjct: 1331 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG----PPGKRGPPGA----AGA 1382
Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-------S 881
G GA G+ G G PP T P G A +P + +P VG +
Sbjct: 1383 EGRQGEKGAKGEA-GAEG-PPGKTGPVGPQGPAG---KPGPEGLRGIPGPVGEQGLPGAA 1437
Query: 882 GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMI 941
G PPG M PPG P + G P +G G+I
Sbjct: 1438 GQDGPPGPMG--------------------PPGLPGLK-------GDPGSKGEKGHPGLI 1470
Query: 942 NPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973
GPP G G SP G G +
Sbjct: 1471 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1502
Score = 96.7 bits (239), Expect = 2e-19
Identities = 229/972 (23%), Positives = 291/972 (29%), Gaps = 190/972 (19%)
Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPG 95
GG ++ A E G+ G + GPP P GK + G G GG G G PG
Sbjct: 556 GGPGSSGAKGESGD----PGPQGPRGVQGPPGPTGKPGKRGRP----GADGGRGMPGEPG 607
Query: 96 AE--------PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPA 147
A+ P L G+ G R PPG G DG P A P
Sbjct: 608 AKGDRGFDGLPGLPGDKGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 665
Query: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF 207
G P G G PG+A G++ GP+ N G
Sbjct: 666 LG---PRGTP----------------GAPGQPGMA--------GVDGPPGPKGNMGPQGE 698
Query: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267
P P P P +G G A G+ PP S
Sbjct: 699 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK-- 756
Query: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG--GDYSGGPQDG 323
GA+G GP G P P + + L +G G+PG GD G
Sbjct: 757 ----GALGPPGPQGPIG-YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 811
Query: 324 GAGK-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381
G+ GP R P P G +G G P
Sbjct: 812 EVGQIGP--------------------------RGEDGPEGPKGRAGPTGDP-------- 837
Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441
P Q G+ G Y +QGP G+PG P A
Sbjct: 838 GPSGQAGEKGKLGVPGLPGYPGRQGPKGST----GFPGFP---------------GANGE 878
Query: 442 MGGLSYTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497
G + P GQ+GP+G G +G T P + PP
Sbjct: 879 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTG-------KPGPKGTSGGDGPPGPPGERG 931
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557
P Q P P + P PP + +P Q+ T ++ PP
Sbjct: 932 PQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPP------- 975
Query: 558 SPYQQQQPQQPAPST--LSQQA--AYPQPQSQQSQQTAYSQQRF---PPPQELSQDSFGS 610
P PQ P T + ++ P P +Q A ++ P PQ +S +
Sbjct: 976 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1035
Query: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS-PG-VSTSGIS 667
P G Q L P P GS + GT G + PG G
Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1095
Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-------RSGPLSPAA 718
GE+ P + P G++GP P P G S + G
Sbjct: 1096 GPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1153
Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS---PRQ 775
G PP PP Q + IA G Q + A P
Sbjct: 1154 DKGENGPPGPPGLQGP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1207
Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGIN 833
P G Q G ++ G GP G G GP+G P+ PN P S G GG+
Sbjct: 1208 PIGLQGLPGPPG-EKGENGDVGPMGPPGPPGPRG--PQGPNGADGPQGPPGSVGSVGGVG 1264
Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893
G G+ G PG P + + G GP A PP G PPG K
Sbjct: 1265 EKGEPGEA-GNPGPPGEAGVGGPKGERGEKGEA--GPPGAAGPP----GAKGPPGDDGPK 1317
Query: 894 TQETAVAMHVAANSIQNRPPGYPN-MNQGGMMG----TGPPYGQGINSMAGMINPQGPPY 948
V PPG P Q G+ G G P G +G P GPP
Sbjct: 1318 GNPGPVGFPGDPG-----PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1372
Query: 949 SMGGTMANNSAG 960
G A + G
Sbjct: 1373 KRGPPGAAGAEG 1384
Score = 90.1 bits (222), Expect = 2e-17
Identities = 237/1039 (22%), Positives = 326/1039 (31%), Gaps = 141/1039 (13%)
Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAV-GPPQPLGKELQDGAESNGGGGGGGAGSGGGP 94
GG+ + E +A A + A+ GPP P+G + G G G G G G P
Sbjct: 512 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG-PVGGPGSSGAKGESGDP 570
Query: 95 GAEPDLKNSNGNAGP--------RPALNNNLTEP--PGGGGGGSSDGV-GAPPHSAAAAL 143
G + + G GP RP + P PG G DG+ G P
Sbjct: 571 GPQGP-RGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 629
Query: 144 PPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP-GL-------AALQSGGGGGLEPY 195
P G P + + + G+ P GL A G G++
Sbjct: 630 RGPQ---GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686
Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255
GP+ N G P P P P +G G A G+ PP
Sbjct: 687 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746
Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG 313
S GA+G GP G P P + + L +G G+PG
Sbjct: 747 PGKEGQSGEK------GALGPPGPQGP-IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799
Query: 314 --------GDYSG----GPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG--------A 353
GD GP+ +GP A + A G
Sbjct: 800 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 859
Query: 354 QQRSHHAPMSPGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412
+Q + PG G G+ AR P Q G P+ G + + G P G
Sbjct: 860 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-PKGTS 918
Query: 413 QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYY 471
G G PG P G + PQ Q +G P G+ G G+ GQ+G+T +
Sbjct: 919 GGDGPPGPP-GERGPQ--------GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 969
Query: 472 NQQSPHPQ-----QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526
+ P Q P P + H P Q P P
Sbjct: 970 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1029
Query: 527 HQQSPA---------PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
+ PA P Q P SP ++ P L +
Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1089
Query: 578 AYPQPQSQQSQQTAYSQQ--RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR 635
P ++ A ++ + P ++ Q G + P+ S G ED +
Sbjct: 1090 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA--GSPG--EDGDKGEIGE 1145
Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRG 694
P ++ P G G P V GI+ GE Q F G G
Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGP-VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204
Query: 695 PSPSPV------GSPASVAQSRS-GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747
P P P+ G P ++ GP+ P PG PR P G + + P S+
Sbjct: 1205 P-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG----PRGPQGPNGA-DGPQGPPGSVG 1258
Query: 748 QDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807
G ++ +PG A +P P G+ G ++ G GP G GP G
Sbjct: 1259 SVGGVGEKG---------EPGEAGNPGPP--GEAGVGGPKGERGEKGEAGPPGAA-GPPG 1306
Query: 808 GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI--------PPYGTLPPGRMS 859
+ P + P N G G P G G GQ G+ P PPG
Sbjct: 1307 A--KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSG 1363
Query: 860 HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-QNRPPGYPNM 918
A P GP PP +G G K + A + P G P
Sbjct: 1364 EAG----PPGPPGKRGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418
Query: 919 NQGGMMGTGPPYG-QGINSMAGMINPQGP--PYSMGGTMAN-NSAGMAASPEMMGLGDVK 974
G+ G P G QG+ AG P GP P + G + S G P ++GL
Sbjct: 1419 E--GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---- 1472
Query: 975 LTPATKMNNKAD-GTPKTE 992
+ P + K D G P T+
Sbjct: 1473 IGPPGEQGEKGDRGLPGTQ 1491
Score = 80.5 bits (197), Expect = 2e-14
Identities = 229/986 (23%), Positives = 299/986 (30%), Gaps = 188/986 (19%)
Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGA-EPDL--KNSNGNAGPR---------- 110
GP P ++ + NG G G G G P EP + + G AGP
Sbjct: 414 GPGVPAETDITE-TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQG 472
Query: 111 ---PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAA 167
P + PPG G +DG+ PP + P YG G + SA A A A
Sbjct: 473 PTGPPGDPGDRGPPGRPGLPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQA 530
Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQN--SHDHGFPNHQYNSYYPNRSAYPPP 225
+ Q + P +G G P GP + + G P Q R PP
Sbjct: 531 ILQQARIALRGPPGPMGLTGRPG---PVGGPGSSGAKGESGDPGPQ-----GPRGVQGPP 582
Query: 226 APAYALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--GGPSAA 282
P G PG G A G + P + + F + G G
Sbjct: 583 GPT--------GKPGKRGRPGADGGRGMPGEPGAK-------GDRGFDGLPGLPGDKGHR 627
Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342
G PQ P + + G +G PG GP+ +G Q A
Sbjct: 628 GERGPQGPPGPPGDDGMRGEDGEIGPRGLPG---EAGPRGLLGPRGTPGAPGQPGMAGVD 684
Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402
+ G Q P PG G G P P P+ G+ PQ G
Sbjct: 685 GPPGPKGNMGPQGE----PGPPGQQGNPGP--QGLPGPQGPIGPPGEKGPQGKPGLAGLP 738
Query: 403 QQQGPPSGP----QQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ--------- 449
GPP P Q G P G Q P YP + + GL ++
Sbjct: 739 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 798
Query: 450 ----------------QIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQP 489
QI P G+ GP G G G Q + P P
Sbjct: 799 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 858
Query: 490 PSQTPHAQPSYQQQPQSQPPQ----LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545
Q P + P + + + P Q+ P A P+ + +
Sbjct: 859 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 918
Query: 546 QSQPPYSQPQAQSPYQQQQP-------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598
P P + P Q P P P +P Q +T + + P
Sbjct: 919 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP----GQRGETGFQGKTGP 974
Query: 599 PPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658
P G + P G Q P + D P G G
Sbjct: 975 PGPGGVVGPQGPTGETGPIGERGHPGPPGPP-GEQGLPGAAGKEGAKGDPGPQGISGKDG 1033
Query: 659 PGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-RSGPLS 715
P +G+ GE+ P +P L G GP P PVGSP + +GP+
Sbjct: 1034 P----AGLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1084
Query: 716 PAAVPGNQMPPRP--------------PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761
PG Q PP P P+G+ D + P + A G + +
Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-DGVQGP-VGLPGPAGPAGSPGEDGDKGE 1142
Query: 762 YSSP-QPGS-----ALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-----GQYGPQG--G 808
P Q GS P P G Q G G GP+G GQ G +G G
Sbjct: 1143 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD-GEPGPRGQQGMFGQKGDEGARG 1201
Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866
+P P L P G G + PMG G PPG
Sbjct: 1202 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG--------------PPGPRG------- 1240
Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926
P GPN A+ PQ G GG+ K + A N PG P G G
Sbjct: 1241 PQGPNGAD-GPQGPPGSVGSVGGVGEKGEPGE-----AGN------PGPP-----GEAGV 1283
Query: 927 GPPYGQ-GINSMAGMINPQGPPYSMG 951
G P G+ G AG GPP + G
Sbjct: 1284 GGPKGERGEKGEAGPPGAAGPPGAKG 1309
Score = 79.3 bits (194), Expect = 4e-14
Identities = 174/760 (22%), Positives = 235/760 (30%), Gaps = 105/760 (13%)
Query: 32 REEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG-----GGGG 86
R E G E A G+ +GQ E +G P G + G + + G G G
Sbjct: 819 RGEDGPEGPKGRAGPTGD-PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 877
Query: 87 GAGSGGGPGAEPDLKNSNGNAGPRPALN-NNLTEPPGGGGGGSSDGVGAPPHSAAAALPP 145
G+ G G +P + G GPR + T PG G DG PP P
Sbjct: 878 EKGARGVAG-KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 936
Query: 146 PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDH 205
GF P G P H G+ G GG + P GP +
Sbjct: 937 GPVGFPGPKG--PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ-GPTGETGPI 993
Query: 206 GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSS 265
G H P P A G SG AG + P + +
Sbjct: 994 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1053
Query: 266 FAQQRFGAMGGGGPSAAGG-----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP 320
+ G G GP + G GT P P P A G +G PG GP
Sbjct: 1054 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1112
Query: 321 QDGGAGKGPADMASQCWGAAAAAA-------AAAAASGGAQQRSHHAPM----------S 363
+GP + A + G + + P +
Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1172
Query: 364 PGSSGGGGQPLART----------------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407
PG +GG G+P R P P P+ G P G N GP
Sbjct: 1173 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232
Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY----G 463
P P G P P G+ PQ P ++ ++GG+ + G GP G G
Sbjct: 1233 PGPP--GPRGPQGPNGADGPQGPPGSV-----GSVGGVGEKGEPGEAGNPGPPGEAGVGG 1285
Query: 464 QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523
+G+ + P P PP ++ PP P+ P + P
Sbjct: 1286 PKGERGEKGEAGP-PGAAGPPGAKGPPGD---------DGPKGNPGPVGFPGDP------ 1329
Query: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583
PP + PA Q + P QP P + P P AA + +
Sbjct: 1330 GPPGEPGPA---GQDGVGGDKGEDGDP-GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1385
Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN-LSLQSRPSSLPDL 642
+ + PP G P + K G E + + LP
Sbjct: 1386 QGEKGAKGEAGAEGPP---------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436
Query: 643 SGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQ-SPFSPHTSPHLPGIRGPSPSPV 700
+G D P G G PG+ G S+GE+ +P P G RG P
Sbjct: 1437 AGQ--DGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-LPGTQ 1491
Query: 701 GSPASVAQSR----SGPLSPAAVPGNQMP-PRPPSGQSDS 735
GSP + +GPL P PG +P P+ P G S
Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPG--LPGPQGPKGNKGS 1529
Score = 52.4 bits (124), Expect = 5e-06
Identities = 106/423 (25%), Positives = 139/423 (32%), Gaps = 95/423 (22%)
Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPA-------QSPFSP------HTSPHLPGIRG 694
D P G +G + P G G+Q NP Q P P P L G+ G
Sbjct: 684 DGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 739
Query: 695 PSPSPVGSPASVAQSRS-------GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747
+ P G P QS GP P PG PR G +D + ++
Sbjct: 740 -ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG----PRGVKG-ADGVRGLKGSKGEKG 793
Query: 748 QD-----RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG--SYQQNSMGSYGPQG 800
+D +G M + P P P G TG S Q G G G
Sbjct: 794 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853
Query: 801 -----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQMH--GQPG 846
G+ GP+G G+P P N A + G G P G+ G G+PG
Sbjct: 854 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 913
Query: 847 IPPYGTLPPGRMSHASMGNRPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVA 904
P GT S G+ P GP P PQ G P P G + + H
Sbjct: 914 --PKGT---------SGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHPG 961
Query: 905 ANSI-----QNRPPGYPNMNQGGMMGT-------------------GPPYGQGINSMAGM 940
+ PPG GG++G GPP QG+ AG
Sbjct: 962 QRGETGFQGKTGPPG-----PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016
Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP-KTESKSKKSS 999
+G P G + + AG+ P GL + P K G P S ++ S
Sbjct: 1017 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1076
Query: 1000 SST 1002
+ T
Sbjct: 1077 AGT 1079
Score = 47.8 bits (112), Expect = 1e-04
Identities = 83/339 (24%), Positives = 111/339 (32%), Gaps = 82/339 (24%)
Query: 661 VSTSGISSSQGEQSNPA-----------QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS 709
++ G +G++ PA P P PG++GP+ P G P
Sbjct: 428 INGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPGDPGD---- 482
Query: 710 RSGPLSPAAVPGNQMPPRPPS-------------GQSDSIMHPSMNQSSIAQDRGYMQRN 756
GP +PG P PP + +I +I Q R
Sbjct: 483 -RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 541
Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPN 814
P P + +PG P GG +G + G GPQG G GP G + P
Sbjct: 542 PPGPMGLTGRPG-------PVGGPGSSGA----KGESGDPGPQGPRGVQGPPGPTGK-PG 589
Query: 815 YNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPNMA 873
P A+ GM G G G G PG+P G H G R P GP
Sbjct: 590 KRGRPGAD-GGRGMPGEPGAKGDRG-FDGLPGLP-------GDKGHR--GERGPQGPP-- 636
Query: 874 NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPN-MNQGGMMGT-GPPYG 931
PPG + ++ + P G P G++G G P
Sbjct: 637 -----------GPPGDDGMRGEDGEIG-----------PRGLPGEAGPRGLLGPRGTPGA 674
Query: 932 QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
G MAG+ P GP +MG G +P GL
Sbjct: 675 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713
Score = 45.8 bits (107), Expect = 4e-04
Identities = 71/258 (27%), Positives = 87/258 (33%), Gaps = 58/258 (22%)
Query: 7 PAAASSLGNPPPP----PP----SELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES 58
P + G P PP PP +E ++ E+ + EAG E G A
Sbjct: 1359 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418
Query: 59 EGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--PALNNN 116
EG G P P+G++ GA G G G G PG P LK G+ G + P L
Sbjct: 1419 EG-LRGIPGPVGEQGLPGA----AGQDGPPGPMGPPGL-PGLKGDPGSKGEKGHPGL-IG 1471
Query: 117 LTEPPGGGGGGSSDGV----GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172
L PPG G G+ G+P +P PA G P
Sbjct: 1472 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP------------------- 1512
Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPP-----PAP 227
PGL Q G G + GP D G P P S PP P P
Sbjct: 1513 ----GPPGLPGPQ--GPKGNKGSTGPAGQKGDSGLPG-------PPGSPGPPGEVIQPLP 1559
Query: 228 AYALSSPRGGTPGSGAAA 245
+ R T G A A
Sbjct: 1560 ILSSKKTRRHTEGMQADA 1577
Score = 40.8 bits (94), Expect = 0.014
Identities = 56/201 (27%), Positives = 67/201 (33%), Gaps = 13/201 (6%)
Query: 791 NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850
N G+YG +G Q G P L AG AG + P G G G PG P
Sbjct: 429 NGHGAYGEKG-----QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPG-DPG 481
Query: 851 GTLPPGRMSHASMGNRPYGPN-MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQ 909
PPGR P P M +P + G P ++ Q A+ A
Sbjct: 482 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ--ARIAL 539
Query: 910 NRPPGYPNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMM 968
PPG M G G G P G +G PQGP G G P
Sbjct: 540 RGPPG--PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597
Query: 969 GLGDVKLTPATKMNNKADGTP 989
G + P K + DG P
Sbjct: 598 GGRGMPGEPGAKGDRGFDGLP 618
Score = 34.3 bits (77), Expect = 1.3
Identities = 78/335 (23%), Positives = 100/335 (29%), Gaps = 70/335 (20%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ-IPPLPGM----------- 1179
PP PAG + GP Q + + GD PP P + +P PG
Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 514
Query: 1180 -SRSNSVGIQDAFNDGSDSTFQKRN----------SMTPNPGYQPSMNTSDMMGRMSYEP 1228
S+ ++ Q+A + + Q+ +T PG +S G
Sbjct: 515 GSKGPTISAQEA---QAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 571
Query: 1229 NKDPYGSM-RKAPGSDPFMSSGQGPNGGMGDPYSRAAG--------PGLGNVAMGPRQHY 1279
+ P G P P G +GG G P A PGL +
Sbjct: 572 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 631
Query: 1280 PYGGP----YDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334
P G P D +R E G IGP G P+ G+ P P Q
Sbjct: 632 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR----------GLLGPRGTPGAPGQPGMA 681
Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFL---- 1390
D G P G P P Q Q P+ P E P P L
Sbjct: 682 GVDGPPGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK--GPQGKPGLAGLP 738
Query: 1391 -------HSGMKMQKA-----GPPVPASHIA-PAP 1412
H G + Q GPP P I P P
Sbjct: 739 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 773
Score = 34.3 bits (77), Expect = 1.3
Identities = 73/325 (22%), Positives = 102/325 (31%), Gaps = 58/325 (17%)
Query: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186
Q K PP P G + GPQ P + + E G PP P P Q LPG + G
Sbjct: 969 QGKTGPPGPGG---VVGPQGPTGETGPIGERGHPGPPGP---PGEQ--GLPG-----AAG 1015
Query: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246
+ A D ++ G+ G + + P
Sbjct: 1016 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP-------------- 1061
Query: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GPYDRVRTEPGIGPEGNMSTGA 1304
QGP G +G P R + G + + P + P G GP GP+G
Sbjct: 1062 ---QGPPGPVGSPGERGSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1117
Query: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP--------------- 1349
Q + P SP + + + + S G++ G P
Sbjct: 1118 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK-GENGPPGPPGLQGPVGAPGIA 1176
Query: 1350 --SGSPFPSQQTTMYQQQQQVSS---PAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVP 1404
G P P Q M+ Q+ + P P P P+ + P + GPP P
Sbjct: 1177 GGDGEPGPRGQQGMFGQKGDEGARGFPGP-PGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1235
Query: 1405 ASHIAPAPVQPPMIRRDITFPPGSV 1429
P Q P PPGSV
Sbjct: 1236 P---GPRGPQGPNGADGPQGPPGSV 1257
Score = 34.3 bits (77), Expect = 1.3
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDL---KPPTPASTPHSQIPPLPGMS----RSNS 1184
PP P G QGP+ + ++ + GD PP P I PLP +S R ++
Sbjct: 1511 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1570
Query: 1185 VGIQ-DA------FNDGSDSTFQKRNSM 1205
G+Q DA ++DG + F NS+
Sbjct: 1571 EGMQADADDNILDYSDGMEEIFGSLNSL 1598
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 102 bits (253), Expect = 5e-21
Identities = 244/1052 (23%), Positives = 312/1052 (29%), Gaps = 206/1052 (19%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERG-----EMKAAAGQESEGP 61
P + PP P K+ G A +RG + G E
Sbjct: 521 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 580
Query: 62 AVGPPQPLGKELQDGAESNGGGGG--GGAGSGG--GPGAEPDLKNSNGNAGPRPALNNNL 117
GPP P G + G + G G G AG G GP P G AG +
Sbjct: 581 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG--------V 632
Query: 118 TEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
PPG G G PP + LP P G P + P
Sbjct: 633 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP--------------- 677
Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF---PNHQYNSYYPNRSAYPPPAPAYA 230
Q PGLA L G G + G + S + G P Q YP
Sbjct: 678 --QGKPGLAGLP--GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 733
Query: 231 LSSPRG-----GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284
L +G G PG G G + + R G G GPS G
Sbjct: 734 LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 793
Query: 285 -----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK-GPADMASQCWG 338
G P P P + G+ G+PG + G + G AGK GP
Sbjct: 794 EKGKLGVPGLPGYPGRQ----GPKGSTGFPGFPGANGEKGAR-GVAGKPGPRGQRGPTGP 848
Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ-PYGG 397
+ A G + G+SGG G P P + G PQ P G
Sbjct: 849 RGSRGARGPTGKPGPK----------GTSGGDGPP--------GPPGERGPQGPQGPVGF 890
Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ-----SAMGGLSYTQQIP 452
P +GPP GP G PG P QR QG+ +G T +
Sbjct: 891 PGP----KGPP-GPPGKDGLPGHP-----GQRGETGFQGKTGPPGPGGVVGPQGPTGETG 940
Query: 453 PYGQQG----PSGYGQQGQTPYYNQQS----PHPQ----------------QQQPPYSQQ 488
P G++G P G+QG ++ P PQ ++ P +Q
Sbjct: 941 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1000
Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS-QQPSQPPHQQSPAPYPSQQSTTQQHPQS 547
P P P P + S+ P +P Q P P + + ++ PQ
Sbjct: 1001 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1060
Query: 548 QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDS 607
P + Q P P PA S + Q + PP Q
Sbjct: 1061 --PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1118
Query: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667
G+ + GQ+ M D+ G G P + G+
Sbjct: 1119 VGAPGIAGGDGEPGPRGQQGM-------------FGQKGDEGARGFPGPPGP-IGLQGLP 1164
Query: 668 SSQGEQS-NPAQSPFSPHTSPHLPGIRGP-----SPSPVGSPASVAQSRSGPLSPAAVPG 721
GE+ N P P P PG RGP + P G P SV G + PG
Sbjct: 1165 GPPGEKGENGDVGPMGP---PGPPGPRGPQGPNGADGPQGPPGSVGSV--GGVGEKGEPG 1219
Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM----QRNPQMPQYSSPQPGSALSPRQPS 777
P PP + A G + P PG P P
Sbjct: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1279
Query: 778 -------GGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGM 828
GQ G + G GP G G+ GP G P P A AG
Sbjct: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG----PPGKRGPPGA----AGA 1331
Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-------S 881
G GA G+ G G PP T P G A +P + +P VG +
Sbjct: 1332 EGRQGEKGAKGEA-GAEG-PPGKTGPVGPQGPAG---KPGPEGLRGIPGPVGEQGLPGAA 1386
Query: 882 GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMI 941
G PPG M PPG P + G P +G G+I
Sbjct: 1387 GQDGPPGPMG--------------------PPGLPGLK-------GDPGSKGEKGHPGLI 1419
Query: 942 NPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973
GPP G G SP G G +
Sbjct: 1420 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1451
Score = 96.7 bits (239), Expect = 2e-19
Identities = 229/972 (23%), Positives = 291/972 (29%), Gaps = 190/972 (19%)
Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPG 95
GG ++ A E G+ G + GPP P GK + G G GG G G PG
Sbjct: 505 GGPGSSGAKGESGD----PGPQGPRGVQGPPGPTGKPGKRGRP----GADGGRGMPGEPG 556
Query: 96 AE--------PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPA 147
A+ P L G+ G R PPG G DG P A P
Sbjct: 557 AKGDRGFDGLPGLPGDKGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 614
Query: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF 207
G P G G PG+A G++ GP+ N G
Sbjct: 615 LG---PRGTP----------------GAPGQPGMA--------GVDGPPGPKGNMGPQGE 647
Query: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267
P P P P +G G A G+ PP S
Sbjct: 648 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK-- 705
Query: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG--GDYSGGPQDG 323
GA+G GP G P P + + L +G G+PG GD G
Sbjct: 706 ----GALGPPGPQGPIG-YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 760
Query: 324 GAGK-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381
G+ GP R P P G +G G P
Sbjct: 761 EVGQIGP--------------------------RGEDGPEGPKGRAGPTGDP-------- 786
Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441
P Q G+ G Y +QGP G+PG P A
Sbjct: 787 GPSGQAGEKGKLGVPGLPGYPGRQGPKGST----GFPGFP---------------GANGE 827
Query: 442 MGGLSYTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497
G + P GQ+GP+G G +G T P + PP
Sbjct: 828 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTG-------KPGPKGTSGGDGPPGPPGERG 880
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557
P Q P P + P PP + +P Q+ T ++ PP
Sbjct: 881 PQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPP------- 924
Query: 558 SPYQQQQPQQPAPST--LSQQA--AYPQPQSQQSQQTAYSQQRF---PPPQELSQDSFGS 610
P PQ P T + ++ P P +Q A ++ P PQ +S +
Sbjct: 925 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 984
Query: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS-PG-VSTSGIS 667
P G Q L P P GS + GT G + PG G
Sbjct: 985 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044
Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-------RSGPLSPAA 718
GE+ P + P G++GP P P G S + G
Sbjct: 1045 GPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102
Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS---PRQ 775
G PP PP Q + IA G Q + A P
Sbjct: 1103 DKGENGPPGPPGLQGP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156
Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGIN 833
P G Q G ++ G GP G G GP+G P+ PN P S G GG+
Sbjct: 1157 PIGLQGLPGPPG-EKGENGDVGPMGPPGPPGPRG--PQGPNGADGPQGPPGSVGSVGGVG 1213
Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893
G G+ G PG P + + G GP A PP G PPG K
Sbjct: 1214 EKGEPGEA-GNPGPPGEAGVGGPKGERGEKGEA--GPPGAAGPP----GAKGPPGDDGPK 1266
Query: 894 TQETAVAMHVAANSIQNRPPGYPN-MNQGGMMG----TGPPYGQGINSMAGMINPQGPPY 948
V PPG P Q G+ G G P G +G P GPP
Sbjct: 1267 GNPGPVGFPGDPG-----PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1321
Query: 949 SMGGTMANNSAG 960
G A + G
Sbjct: 1322 KRGPPGAAGAEG 1333
Score = 90.1 bits (222), Expect = 2e-17
Identities = 237/1039 (22%), Positives = 326/1039 (31%), Gaps = 141/1039 (13%)
Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAV-GPPQPLGKELQDGAESNGGGGGGGAGSGGGP 94
GG+ + E +A A + A+ GPP P+G + G G G G G G P
Sbjct: 461 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG-PVGGPGSSGAKGESGDP 519
Query: 95 GAEPDLKNSNGNAGP--------RPALNNNLTEP--PGGGGGGSSDGV-GAPPHSAAAAL 143
G + + G GP RP + P PG G DG+ G P
Sbjct: 520 GPQGP-RGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 578
Query: 144 PPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP-GL-------AALQSGGGGGLEPY 195
P G P + + + G+ P GL A G G++
Sbjct: 579 RGPQ---GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635
Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255
GP+ N G P P P P +G G A G+ PP
Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695
Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG 313
S GA+G GP G P P + + L +G G+PG
Sbjct: 696 PGKEGQSGEK------GALGPPGPQGP-IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 748
Query: 314 --------GDYSG----GPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG--------A 353
GD GP+ +GP A + A G
Sbjct: 749 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 808
Query: 354 QQRSHHAPMSPGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412
+Q + PG G G+ AR P Q G P+ G + + G P G
Sbjct: 809 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-PKGTS 867
Query: 413 QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYY 471
G G PG P G + PQ Q +G P G+ G G+ GQ+G+T +
Sbjct: 868 GGDGPPGPP-GERGPQ--------GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 918
Query: 472 NQQSPHPQ-----QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526
+ P Q P P + H P Q P P
Sbjct: 919 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 978
Query: 527 HQQSPA---------PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
+ PA P Q P SP ++ P L +
Sbjct: 979 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1038
Query: 578 AYPQPQSQQSQQTAYSQQ--RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR 635
P ++ A ++ + P ++ Q G + P+ S G ED +
Sbjct: 1039 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA--GSPG--EDGDKGEIGE 1094
Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRG 694
P ++ P G G P V GI+ GE Q F G G
Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGP-VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153
Query: 695 PSPSPV------GSPASVAQSRS-GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747
P P P+ G P ++ GP+ P PG PR P G + + P S+
Sbjct: 1154 P-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG----PRGPQGPNGA-DGPQGPPGSVG 1207
Query: 748 QDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807
G ++ +PG A +P P G+ G ++ G GP G GP G
Sbjct: 1208 SVGGVGEKG---------EPGEAGNPGPP--GEAGVGGPKGERGEKGEAGPPGAA-GPPG 1255
Query: 808 GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI--------PPYGTLPPGRMS 859
+ P + P N G G P G G GQ G+ P PPG
Sbjct: 1256 A--KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSG 1312
Query: 860 HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-QNRPPGYPNM 918
A P GP PP +G G K + A + P G P
Sbjct: 1313 EAG----PPGPPGKRGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367
Query: 919 NQGGMMGTGPPYG-QGINSMAGMINPQGP--PYSMGGTMAN-NSAGMAASPEMMGLGDVK 974
G+ G P G QG+ AG P GP P + G + S G P ++GL
Sbjct: 1368 E--GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---- 1421
Query: 975 LTPATKMNNKAD-GTPKTE 992
+ P + K D G P T+
Sbjct: 1422 IGPPGEQGEKGDRGLPGTQ 1440
Score = 80.5 bits (197), Expect = 2e-14
Identities = 229/986 (23%), Positives = 299/986 (30%), Gaps = 188/986 (19%)
Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGA-EPDL--KNSNGNAGPR---------- 110
GP P ++ + NG G G G G P EP + + G AGP
Sbjct: 363 GPGVPAETDITE-TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQG 421
Query: 111 ---PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAA 167
P + PPG G +DG+ PP + P YG G + SA A A A
Sbjct: 422 PTGPPGDPGDRGPPGRPGLPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQA 479
Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQN--SHDHGFPNHQYNSYYPNRSAYPPP 225
+ Q + P +G G P GP + + G P Q R PP
Sbjct: 480 ILQQARIALRGPPGPMGLTGRPG---PVGGPGSSGAKGESGDPGPQ-----GPRGVQGPP 531
Query: 226 APAYALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--GGPSAA 282
P G PG G A G + P + + F + G G
Sbjct: 532 GPT--------GKPGKRGRPGADGGRGMPGEPGAK-------GDRGFDGLPGLPGDKGHR 576
Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342
G PQ P + + G +G PG GP+ +G Q A
Sbjct: 577 GERGPQGPPGPPGDDGMRGEDGEIGPRGLPG---EAGPRGLLGPRGTPGAPGQPGMAGVD 633
Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402
+ G Q P PG G G P P P+ G+ PQ G
Sbjct: 634 GPPGPKGNMGPQGE----PGPPGQQGNPGP--QGLPGPQGPIGPPGEKGPQGKPGLAGLP 687
Query: 403 QQQGPPSGP----QQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ--------- 449
GPP P Q G P G Q P YP + + GL ++
Sbjct: 688 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 747
Query: 450 ----------------QIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQP 489
QI P G+ GP G G G Q + P P
Sbjct: 748 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 807
Query: 490 PSQTPHAQPSYQQQPQSQPPQ----LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545
Q P + P + + + P Q+ P A P+ + +
Sbjct: 808 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867
Query: 546 QSQPPYSQPQAQSPYQQQQP-------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598
P P + P Q P P P +P Q +T + + P
Sbjct: 868 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP----GQRGETGFQGKTGP 923
Query: 599 PPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658
P G + P G Q P + D P G G
Sbjct: 924 PGPGGVVGPQGPTGETGPIGERGHPGPPGPP-GEQGLPGAAGKEGAKGDPGPQGISGKDG 982
Query: 659 PGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-RSGPLS 715
P +G+ GE+ P +P L G GP P PVGSP + +GP+
Sbjct: 983 P----AGLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1033
Query: 716 PAAVPGNQMPPRP--------------PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761
PG Q PP P P+G+ D + P + A G + +
Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-DGVQGP-VGLPGPAGPAGSPGEDGDKGE 1091
Query: 762 YSSP-QPGS-----ALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-----GQYGPQG--G 808
P Q GS P P G Q G G GP+G GQ G +G G
Sbjct: 1092 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD-GEPGPRGQQGMFGQKGDEGARG 1150
Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866
+P P L P G G + PMG G PPG
Sbjct: 1151 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG--------------PPGPRG------- 1189
Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926
P GPN A+ PQ G GG+ K + A N PG P G G
Sbjct: 1190 PQGPNGAD-GPQGPPGSVGSVGGVGEKGEPGE-----AGN------PGPP-----GEAGV 1232
Query: 927 GPPYGQ-GINSMAGMINPQGPPYSMG 951
G P G+ G AG GPP + G
Sbjct: 1233 GGPKGERGEKGEAGPPGAAGPPGAKG 1258
Score = 79.3 bits (194), Expect = 4e-14
Identities = 174/760 (22%), Positives = 235/760 (30%), Gaps = 105/760 (13%)
Query: 32 REEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG-----GGGG 86
R E G E A G+ +GQ E +G P G + G + + G G G
Sbjct: 768 RGEDGPEGPKGRAGPTGD-PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826
Query: 87 GAGSGGGPGAEPDLKNSNGNAGPRPALN-NNLTEPPGGGGGGSSDGVGAPPHSAAAALPP 145
G+ G G +P + G GPR + T PG G DG PP P
Sbjct: 827 EKGARGVAG-KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 885
Query: 146 PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDH 205
GF P G P H G+ G GG + P GP +
Sbjct: 886 GPVGFPGPKG--PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ-GPTGETGPI 942
Query: 206 GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSS 265
G H P P A G SG AG + P + +
Sbjct: 943 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002
Query: 266 FAQQRFGAMGGGGPSAAGG-----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP 320
+ G G GP + G GT P P P A G +G PG GP
Sbjct: 1003 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1061
Query: 321 QDGGAGKGPADMASQCWGAAAAAA-------AAAAASGGAQQRSHHAPM----------S 363
+GP + A + G + + P +
Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121
Query: 364 PGSSGGGGQPLART----------------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407
PG +GG G+P R P P P+ G P G N GP
Sbjct: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181
Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY----G 463
P P G P P G+ PQ P ++ ++GG+ + G GP G G
Sbjct: 1182 PGPP--GPRGPQGPNGADGPQGPPGSV-----GSVGGVGEKGEPGEAGNPGPPGEAGVGG 1234
Query: 464 QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523
+G+ + P P PP ++ PP P+ P + P
Sbjct: 1235 PKGERGEKGEAGP-PGAAGPPGAKGPPGD---------DGPKGNPGPVGFPGDP------ 1278
Query: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583
PP + PA Q + P QP P + P P AA + +
Sbjct: 1279 GPPGEPGPA---GQDGVGGDKGEDGDP-GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1334
Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN-LSLQSRPSSLPDL 642
+ + PP G P + K G E + + LP
Sbjct: 1335 QGEKGAKGEAGAEGPP---------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385
Query: 643 SGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQ-SPFSPHTSPHLPGIRGPSPSPV 700
+G D P G G PG+ G S+GE+ +P P G RG P
Sbjct: 1386 AGQ--DGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-LPGTQ 1440
Query: 701 GSPASVAQSR----SGPLSPAAVPGNQMP-PRPPSGQSDS 735
GSP + +GPL P PG +P P+ P G S
Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPG--LPGPQGPKGNKGS 1478
Score = 52.4 bits (124), Expect = 5e-06
Identities = 106/423 (25%), Positives = 139/423 (32%), Gaps = 95/423 (22%)
Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPA-------QSPFSP------HTSPHLPGIRG 694
D P G +G + P G G+Q NP Q P P P L G+ G
Sbjct: 633 DGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 688
Query: 695 PSPSPVGSPASVAQSRS-------GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747
+ P G P QS GP P PG PR G +D + ++
Sbjct: 689 -ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG----PRGVKG-ADGVRGLKGSKGEKG 742
Query: 748 QD-----RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG--SYQQNSMGSYGPQG 800
+D +G M + P P P G TG S Q G G G
Sbjct: 743 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802
Query: 801 -----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQMH--GQPG 846
G+ GP+G G+P P N A + G G P G+ G G+PG
Sbjct: 803 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 862
Query: 847 IPPYGTLPPGRMSHASMGNRPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVA 904
P GT S G+ P GP P PQ G P P G + + H
Sbjct: 863 --PKGT---------SGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHPG 910
Query: 905 ANSI-----QNRPPGYPNMNQGGMMGT-------------------GPPYGQGINSMAGM 940
+ PPG GG++G GPP QG+ AG
Sbjct: 911 QRGETGFQGKTGPPG-----PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965
Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP-KTESKSKKSS 999
+G P G + + AG+ P GL + P K G P S ++ S
Sbjct: 966 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1025
Query: 1000 SST 1002
+ T
Sbjct: 1026 AGT 1028
Score = 47.8 bits (112), Expect = 1e-04
Identities = 83/339 (24%), Positives = 111/339 (32%), Gaps = 82/339 (24%)
Query: 661 VSTSGISSSQGEQSNPA-----------QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS 709
++ G +G++ PA P P PG++GP+ P G P
Sbjct: 377 INGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPGDPGD---- 431
Query: 710 RSGPLSPAAVPGNQMPPRPPS-------------GQSDSIMHPSMNQSSIAQDRGYMQRN 756
GP +PG P PP + +I +I Q R
Sbjct: 432 -RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 490
Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPN 814
P P + +PG P GG +G + G GPQG G GP G + P
Sbjct: 491 PPGPMGLTGRPG-------PVGGPGSSGA----KGESGDPGPQGPRGVQGPPGPTGK-PG 538
Query: 815 YNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPNMA 873
P A+ GM G G G G PG+P G H G R P GP
Sbjct: 539 KRGRPGAD-GGRGMPGEPGAKGDRG-FDGLPGLP-------GDKGHR--GERGPQGPP-- 585
Query: 874 NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPN-MNQGGMMGT-GPPYG 931
PPG + ++ + P G P G++G G P
Sbjct: 586 -----------GPPGDDGMRGEDGEIG-----------PRGLPGEAGPRGLLGPRGTPGA 623
Query: 932 QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
G MAG+ P GP +MG G +P GL
Sbjct: 624 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662
Score = 45.8 bits (107), Expect = 4e-04
Identities = 71/258 (27%), Positives = 87/258 (33%), Gaps = 58/258 (22%)
Query: 7 PAAASSLGNPPPP----PP----SELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES 58
P + G P PP PP +E ++ E+ + EAG E G A
Sbjct: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367
Query: 59 EGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--PALNNN 116
EG G P P+G++ GA G G G G PG P LK G+ G + P L
Sbjct: 1368 EG-LRGIPGPVGEQGLPGA----AGQDGPPGPMGPPGL-PGLKGDPGSKGEKGHPGL-IG 1420
Query: 117 LTEPPGGGGGGSSDGV----GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172
L PPG G G+ G+P +P PA G P
Sbjct: 1421 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP------------------- 1461
Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPP-----PAP 227
PGL Q G G + GP D G P P S PP P P
Sbjct: 1462 ----GPPGLPGPQ--GPKGNKGSTGPAGQKGDSGLPG-------PPGSPGPPGEVIQPLP 1508
Query: 228 AYALSSPRGGTPGSGAAA 245
+ R T G A A
Sbjct: 1509 ILSSKKTRRHTEGMQADA 1526
Score = 40.8 bits (94), Expect = 0.014
Identities = 56/201 (27%), Positives = 67/201 (33%), Gaps = 13/201 (6%)
Query: 791 NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850
N G+YG +G Q G P L AG AG + P G G G PG P
Sbjct: 378 NGHGAYGEKG-----QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPG-DPG 430
Query: 851 GTLPPGRMSHASMGNRPYGPN-MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQ 909
PPGR P P M +P + G P ++ Q A+ A
Sbjct: 431 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ--ARIAL 488
Query: 910 NRPPGYPNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMM 968
PPG M G G G P G +G PQGP G G P
Sbjct: 489 RGPPG--PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546
Query: 969 GLGDVKLTPATKMNNKADGTP 989
G + P K + DG P
Sbjct: 547 GGRGMPGEPGAKGDRGFDGLP 567
Score = 34.3 bits (77), Expect = 1.3
Identities = 78/335 (23%), Positives = 100/335 (29%), Gaps = 70/335 (20%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ-IPPLPGM----------- 1179
PP PAG + GP Q + + GD PP P + +P PG
Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 463
Query: 1180 -SRSNSVGIQDAFNDGSDSTFQKRN----------SMTPNPGYQPSMNTSDMMGRMSYEP 1228
S+ ++ Q+A + + Q+ +T PG +S G
Sbjct: 464 GSKGPTISAQEA---QAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 520
Query: 1229 NKDPYGSM-RKAPGSDPFMSSGQGPNGGMGDPYSRAAG--------PGLGNVAMGPRQHY 1279
+ P G P P G +GG G P A PGL +
Sbjct: 521 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 580
Query: 1280 PYGGP----YDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334
P G P D +R E G IGP G P+ G+ P P Q
Sbjct: 581 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR----------GLLGPRGTPGAPGQPGMA 630
Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFL---- 1390
D G P G P P Q Q P+ P E P P L
Sbjct: 631 GVDGPPGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK--GPQGKPGLAGLP 687
Query: 1391 -------HSGMKMQKA-----GPPVPASHIA-PAP 1412
H G + Q GPP P I P P
Sbjct: 688 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 722
Score = 34.3 bits (77), Expect = 1.3
Identities = 73/325 (22%), Positives = 102/325 (31%), Gaps = 58/325 (17%)
Query: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186
Q K PP P G + GPQ P + + E G PP P P Q LPG + G
Sbjct: 918 QGKTGPPGPGG---VVGPQGPTGETGPIGERGHPGPPGP---PGEQ--GLPG-----AAG 964
Query: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246
+ A D ++ G+ G + + P
Sbjct: 965 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP-------------- 1010
Query: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GPYDRVRTEPGIGPEGNMSTGA 1304
QGP G +G P R + G + + P + P G GP GP+G
Sbjct: 1011 ---QGPPGPVGSPGERGSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1066
Query: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP--------------- 1349
Q + P SP + + + + S G++ G P
Sbjct: 1067 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK-GENGPPGPPGLQGPVGAPGIA 1125
Query: 1350 --SGSPFPSQQTTMYQQQQQVSS---PAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVP 1404
G P P Q M+ Q+ + P P P P+ + P + GPP P
Sbjct: 1126 GGDGEPGPRGQQGMFGQKGDEGARGFPGP-PGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1184
Query: 1405 ASHIAPAPVQPPMIRRDITFPPGSV 1429
P Q P PPGSV
Sbjct: 1185 P---GPRGPQGPNGADGPQGPPGSV 1206
Score = 34.3 bits (77), Expect = 1.3
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDL---KPPTPASTPHSQIPPLPGMS----RSNS 1184
PP P G QGP+ + ++ + GD PP P I PLP +S R ++
Sbjct: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1519
Query: 1185 VGIQ-DA------FNDGSDSTFQKRNSM 1205
G+Q DA ++DG + F NS+
Sbjct: 1520 EGMQADADDNILDYSDGMEEIFGSLNSL 1547
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 102 bits (253), Expect = 5e-21
Identities = 244/1052 (23%), Positives = 312/1052 (29%), Gaps = 206/1052 (19%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERG-----EMKAAAGQESEGP 61
P + PP P K+ G A +RG + G E
Sbjct: 560 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 619
Query: 62 AVGPPQPLGKELQDGAESNGGGGG--GGAGSGG--GPGAEPDLKNSNGNAGPRPALNNNL 117
GPP P G + G + G G G AG G GP P G AG +
Sbjct: 620 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG--------V 671
Query: 118 TEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
PPG G G PP + LP P G P + P
Sbjct: 672 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP--------------- 716
Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF---PNHQYNSYYPNRSAYPPPAPAYA 230
Q PGLA L G G + G + S + G P Q YP
Sbjct: 717 --QGKPGLAGLP--GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 772
Query: 231 LSSPRG-----GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284
L +G G PG G G + + R G G GPS G
Sbjct: 773 LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 832
Query: 285 -----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK-GPADMASQCWG 338
G P P P + G+ G+PG + G + G AGK GP
Sbjct: 833 EKGKLGVPGLPGYPGRQ----GPKGSTGFPGFPGANGEKGAR-GVAGKPGPRGQRGPTGP 887
Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ-PYGG 397
+ A G + G+SGG G P P + G PQ P G
Sbjct: 888 RGSRGARGPTGKPGPK----------GTSGGDGPP--------GPPGERGPQGPQGPVGF 929
Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ-----SAMGGLSYTQQIP 452
P +GPP GP G PG P QR QG+ +G T +
Sbjct: 930 PGP----KGPP-GPPGKDGLPGHP-----GQRGETGFQGKTGPPGPGGVVGPQGPTGETG 979
Query: 453 PYGQQG----PSGYGQQGQTPYYNQQS----PHPQ----------------QQQPPYSQQ 488
P G++G P G+QG ++ P PQ ++ P +Q
Sbjct: 980 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1039
Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS-QQPSQPPHQQSPAPYPSQQSTTQQHPQS 547
P P P P + S+ P +P Q P P + + ++ PQ
Sbjct: 1040 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1099
Query: 548 QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDS 607
P + Q P P PA S + Q + PP Q
Sbjct: 1100 --PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1157
Query: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667
G+ + GQ+ M D+ G G P + G+
Sbjct: 1158 VGAPGIAGGDGEPGPRGQQGM-------------FGQKGDEGARGFPGPPGP-IGLQGLP 1203
Query: 668 SSQGEQS-NPAQSPFSPHTSPHLPGIRGP-----SPSPVGSPASVAQSRSGPLSPAAVPG 721
GE+ N P P P PG RGP + P G P SV G + PG
Sbjct: 1204 GPPGEKGENGDVGPMGP---PGPPGPRGPQGPNGADGPQGPPGSVGSV--GGVGEKGEPG 1258
Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM----QRNPQMPQYSSPQPGSALSPRQPS 777
P PP + A G + P PG P P
Sbjct: 1259 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1318
Query: 778 -------GGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGM 828
GQ G + G GP G G+ GP G P P A AG
Sbjct: 1319 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG----PPGKRGPPGA----AGA 1370
Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-------S 881
G GA G+ G G PP T P G A +P + +P VG +
Sbjct: 1371 EGRQGEKGAKGEA-GAEG-PPGKTGPVGPQGPAG---KPGPEGLRGIPGPVGEQGLPGAA 1425
Query: 882 GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMI 941
G PPG M PPG P + G P +G G+I
Sbjct: 1426 GQDGPPGPMG--------------------PPGLPGLK-------GDPGSKGEKGHPGLI 1458
Query: 942 NPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973
GPP G G SP G G +
Sbjct: 1459 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1490
Score = 96.7 bits (239), Expect = 2e-19
Identities = 229/972 (23%), Positives = 291/972 (29%), Gaps = 190/972 (19%)
Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPG 95
GG ++ A E G+ G + GPP P GK + G G GG G G PG
Sbjct: 544 GGPGSSGAKGESGD----PGPQGPRGVQGPPGPTGKPGKRGRP----GADGGRGMPGEPG 595
Query: 96 AE--------PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPA 147
A+ P L G+ G R PPG G DG P A P
Sbjct: 596 AKGDRGFDGLPGLPGDKGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 653
Query: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF 207
G P G G PG+A G++ GP+ N G
Sbjct: 654 LG---PRGTP----------------GAPGQPGMA--------GVDGPPGPKGNMGPQGE 686
Query: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267
P P P P +G G A G+ PP S
Sbjct: 687 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK-- 744
Query: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG--GDYSGGPQDG 323
GA+G GP G P P + + L +G G+PG GD G
Sbjct: 745 ----GALGPPGPQGPIG-YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 799
Query: 324 GAGK-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381
G+ GP R P P G +G G P
Sbjct: 800 EVGQIGP--------------------------RGEDGPEGPKGRAGPTGDP-------- 825
Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441
P Q G+ G Y +QGP G+PG P A
Sbjct: 826 GPSGQAGEKGKLGVPGLPGYPGRQGPKGST----GFPGFP---------------GANGE 866
Query: 442 MGGLSYTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497
G + P GQ+GP+G G +G T P + PP
Sbjct: 867 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTG-------KPGPKGTSGGDGPPGPPGERG 919
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557
P Q P P + P PP + +P Q+ T ++ PP
Sbjct: 920 PQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPP------- 963
Query: 558 SPYQQQQPQQPAPST--LSQQA--AYPQPQSQQSQQTAYSQQRF---PPPQELSQDSFGS 610
P PQ P T + ++ P P +Q A ++ P PQ +S +
Sbjct: 964 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1023
Query: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS-PG-VSTSGIS 667
P G Q L P P GS + GT G + PG G
Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083
Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-------RSGPLSPAA 718
GE+ P + P G++GP P P G S + G
Sbjct: 1084 GPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141
Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS---PRQ 775
G PP PP Q + IA G Q + A P
Sbjct: 1142 DKGENGPPGPPGLQGP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195
Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGIN 833
P G Q G ++ G GP G G GP+G P+ PN P S G GG+
Sbjct: 1196 PIGLQGLPGPPG-EKGENGDVGPMGPPGPPGPRG--PQGPNGADGPQGPPGSVGSVGGVG 1252
Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893
G G+ G PG P + + G GP A PP G PPG K
Sbjct: 1253 EKGEPGEA-GNPGPPGEAGVGGPKGERGEKGEA--GPPGAAGPP----GAKGPPGDDGPK 1305
Query: 894 TQETAVAMHVAANSIQNRPPGYPN-MNQGGMMG----TGPPYGQGINSMAGMINPQGPPY 948
V PPG P Q G+ G G P G +G P GPP
Sbjct: 1306 GNPGPVGFPGDPG-----PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1360
Query: 949 SMGGTMANNSAG 960
G A + G
Sbjct: 1361 KRGPPGAAGAEG 1372
Score = 90.1 bits (222), Expect = 2e-17
Identities = 237/1039 (22%), Positives = 326/1039 (31%), Gaps = 141/1039 (13%)
Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAV-GPPQPLGKELQDGAESNGGGGGGGAGSGGGP 94
GG+ + E +A A + A+ GPP P+G + G G G G G G P
Sbjct: 500 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG-PVGGPGSSGAKGESGDP 558
Query: 95 GAEPDLKNSNGNAGP--------RPALNNNLTEP--PGGGGGGSSDGV-GAPPHSAAAAL 143
G + + G GP RP + P PG G DG+ G P
Sbjct: 559 GPQGP-RGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 617
Query: 144 PPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP-GL-------AALQSGGGGGLEPY 195
P G P + + + G+ P GL A G G++
Sbjct: 618 RGPQ---GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674
Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255
GP+ N G P P P P +G G A G+ PP
Sbjct: 675 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734
Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG 313
S GA+G GP G P P + + L +G G+PG
Sbjct: 735 PGKEGQSGEK------GALGPPGPQGP-IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787
Query: 314 --------GDYSG----GPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG--------A 353
GD GP+ +GP A + A G
Sbjct: 788 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 847
Query: 354 QQRSHHAPMSPGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412
+Q + PG G G+ AR P Q G P+ G + + G P G
Sbjct: 848 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-PKGTS 906
Query: 413 QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYY 471
G G PG P G + PQ Q +G P G+ G G+ GQ+G+T +
Sbjct: 907 GGDGPPGPP-GERGPQ--------GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957
Query: 472 NQQSPHPQ-----QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526
+ P Q P P + H P Q P P
Sbjct: 958 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017
Query: 527 HQQSPA---------PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
+ PA P Q P SP ++ P L +
Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077
Query: 578 AYPQPQSQQSQQTAYSQQ--RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR 635
P ++ A ++ + P ++ Q G + P+ S G ED +
Sbjct: 1078 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA--GSPG--EDGDKGEIGE 1133
Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRG 694
P ++ P G G P V GI+ GE Q F G G
Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGP-VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192
Query: 695 PSPSPV------GSPASVAQSRS-GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747
P P P+ G P ++ GP+ P PG PR P G + + P S+
Sbjct: 1193 P-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG----PRGPQGPNGA-DGPQGPPGSVG 1246
Query: 748 QDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807
G ++ +PG A +P P G+ G ++ G GP G GP G
Sbjct: 1247 SVGGVGEKG---------EPGEAGNPGPP--GEAGVGGPKGERGEKGEAGPPGAA-GPPG 1294
Query: 808 GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI--------PPYGTLPPGRMS 859
+ P + P N G G P G G GQ G+ P PPG
Sbjct: 1295 A--KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSG 1351
Query: 860 HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-QNRPPGYPNM 918
A P GP PP +G G K + A + P G P
Sbjct: 1352 EAG----PPGPPGKRGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406
Query: 919 NQGGMMGTGPPYG-QGINSMAGMINPQGP--PYSMGGTMAN-NSAGMAASPEMMGLGDVK 974
G+ G P G QG+ AG P GP P + G + S G P ++GL
Sbjct: 1407 E--GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---- 1460
Query: 975 LTPATKMNNKAD-GTPKTE 992
+ P + K D G P T+
Sbjct: 1461 IGPPGEQGEKGDRGLPGTQ 1479
Score = 80.5 bits (197), Expect = 2e-14
Identities = 229/986 (23%), Positives = 299/986 (30%), Gaps = 188/986 (19%)
Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGA-EPDL--KNSNGNAGPR---------- 110
GP P ++ + NG G G G G P EP + + G AGP
Sbjct: 402 GPGVPAETDITE-TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQG 460
Query: 111 ---PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAA 167
P + PPG G +DG+ PP + P YG G + SA A A A
Sbjct: 461 PTGPPGDPGDRGPPGRPGLPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQA 518
Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQN--SHDHGFPNHQYNSYYPNRSAYPPP 225
+ Q + P +G G P GP + + G P Q R PP
Sbjct: 519 ILQQARIALRGPPGPMGLTGRPG---PVGGPGSSGAKGESGDPGPQ-----GPRGVQGPP 570
Query: 226 APAYALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--GGPSAA 282
P G PG G A G + P + + F + G G
Sbjct: 571 GPT--------GKPGKRGRPGADGGRGMPGEPGAK-------GDRGFDGLPGLPGDKGHR 615
Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342
G PQ P + + G +G PG GP+ +G Q A
Sbjct: 616 GERGPQGPPGPPGDDGMRGEDGEIGPRGLPG---EAGPRGLLGPRGTPGAPGQPGMAGVD 672
Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402
+ G Q P PG G G P P P+ G+ PQ G
Sbjct: 673 GPPGPKGNMGPQGE----PGPPGQQGNPGP--QGLPGPQGPIGPPGEKGPQGKPGLAGLP 726
Query: 403 QQQGPPSGP----QQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ--------- 449
GPP P Q G P G Q P YP + + GL ++
Sbjct: 727 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 786
Query: 450 ----------------QIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQP 489
QI P G+ GP G G G Q + P P
Sbjct: 787 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 846
Query: 490 PSQTPHAQPSYQQQPQSQPPQ----LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545
Q P + P + + + P Q+ P A P+ + +
Sbjct: 847 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906
Query: 546 QSQPPYSQPQAQSPYQQQQP-------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598
P P + P Q P P P +P Q +T + + P
Sbjct: 907 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP----GQRGETGFQGKTGP 962
Query: 599 PPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658
P G + P G Q P + D P G G
Sbjct: 963 PGPGGVVGPQGPTGETGPIGERGHPGPPGPP-GEQGLPGAAGKEGAKGDPGPQGISGKDG 1021
Query: 659 PGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-RSGPLS 715
P +G+ GE+ P +P L G GP P PVGSP + +GP+
Sbjct: 1022 P----AGLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1072
Query: 716 PAAVPGNQMPPRP--------------PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761
PG Q PP P P+G+ D + P + A G + +
Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-DGVQGP-VGLPGPAGPAGSPGEDGDKGE 1130
Query: 762 YSSP-QPGS-----ALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-----GQYGPQG--G 808
P Q GS P P G Q G G GP+G GQ G +G G
Sbjct: 1131 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD-GEPGPRGQQGMFGQKGDEGARG 1189
Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866
+P P L P G G + PMG G PPG
Sbjct: 1190 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG--------------PPGPRG------- 1228
Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926
P GPN A+ PQ G GG+ K + A N PG P G G
Sbjct: 1229 PQGPNGAD-GPQGPPGSVGSVGGVGEKGEPGE-----AGN------PGPP-----GEAGV 1271
Query: 927 GPPYGQ-GINSMAGMINPQGPPYSMG 951
G P G+ G AG GPP + G
Sbjct: 1272 GGPKGERGEKGEAGPPGAAGPPGAKG 1297
Score = 79.3 bits (194), Expect = 4e-14
Identities = 174/760 (22%), Positives = 235/760 (30%), Gaps = 105/760 (13%)
Query: 32 REEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG-----GGGG 86
R E G E A G+ +GQ E +G P G + G + + G G G
Sbjct: 807 RGEDGPEGPKGRAGPTGD-PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865
Query: 87 GAGSGGGPGAEPDLKNSNGNAGPRPALN-NNLTEPPGGGGGGSSDGVGAPPHSAAAALPP 145
G+ G G +P + G GPR + T PG G DG PP P
Sbjct: 866 EKGARGVAG-KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 924
Query: 146 PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDH 205
GF P G P H G+ G GG + P GP +
Sbjct: 925 GPVGFPGPKG--PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ-GPTGETGPI 981
Query: 206 GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSS 265
G H P P A G SG AG + P + +
Sbjct: 982 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041
Query: 266 FAQQRFGAMGGGGPSAAGG-----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP 320
+ G G GP + G GT P P P A G +G PG GP
Sbjct: 1042 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1100
Query: 321 QDGGAGKGPADMASQCWGAAAAAA-------AAAAASGGAQQRSHHAPM----------S 363
+GP + A + G + + P +
Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1160
Query: 364 PGSSGGGGQPLART----------------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407
PG +GG G+P R P P P+ G P G N GP
Sbjct: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220
Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY----G 463
P P G P P G+ PQ P ++ ++GG+ + G GP G G
Sbjct: 1221 PGPP--GPRGPQGPNGADGPQGPPGSV-----GSVGGVGEKGEPGEAGNPGPPGEAGVGG 1273
Query: 464 QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523
+G+ + P P PP ++ PP P+ P + P
Sbjct: 1274 PKGERGEKGEAGP-PGAAGPPGAKGPPGD---------DGPKGNPGPVGFPGDP------ 1317
Query: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583
PP + PA Q + P QP P + P P AA + +
Sbjct: 1318 GPPGEPGPA---GQDGVGGDKGEDGDP-GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1373
Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN-LSLQSRPSSLPDL 642
+ + PP G P + K G E + + LP
Sbjct: 1374 QGEKGAKGEAGAEGPP---------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424
Query: 643 SGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQ-SPFSPHTSPHLPGIRGPSPSPV 700
+G D P G G PG+ G S+GE+ +P P G RG P
Sbjct: 1425 AGQ--DGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-LPGTQ 1479
Query: 701 GSPASVAQSR----SGPLSPAAVPGNQMP-PRPPSGQSDS 735
GSP + +GPL P PG +P P+ P G S
Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPG--LPGPQGPKGNKGS 1517
Score = 52.4 bits (124), Expect = 5e-06
Identities = 106/423 (25%), Positives = 139/423 (32%), Gaps = 95/423 (22%)
Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPA-------QSPFSP------HTSPHLPGIRG 694
D P G +G + P G G+Q NP Q P P P L G+ G
Sbjct: 672 DGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 727
Query: 695 PSPSPVGSPASVAQSRS-------GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747
+ P G P QS GP P PG PR G +D + ++
Sbjct: 728 -ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG----PRGVKG-ADGVRGLKGSKGEKG 781
Query: 748 QD-----RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG--SYQQNSMGSYGPQG 800
+D +G M + P P P G TG S Q G G G
Sbjct: 782 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841
Query: 801 -----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQMH--GQPG 846
G+ GP+G G+P P N A + G G P G+ G G+PG
Sbjct: 842 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 901
Query: 847 IPPYGTLPPGRMSHASMGNRPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVA 904
P GT S G+ P GP P PQ G P P G + + H
Sbjct: 902 --PKGT---------SGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHPG 949
Query: 905 ANSI-----QNRPPGYPNMNQGGMMGT-------------------GPPYGQGINSMAGM 940
+ PPG GG++G GPP QG+ AG
Sbjct: 950 QRGETGFQGKTGPPG-----PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004
Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP-KTESKSKKSS 999
+G P G + + AG+ P GL + P K G P S ++ S
Sbjct: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1064
Query: 1000 SST 1002
+ T
Sbjct: 1065 AGT 1067
Score = 48.9 bits (115), Expect = 5e-05
Identities = 112/521 (21%), Positives = 176/521 (33%), Gaps = 102/521 (19%)
Query: 493 TPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYS 552
+P S + Q+Q PQ+ P + + ++ A Y +S T+ ++ +
Sbjct: 240 SPDCDSSAPKAAQAQEPQIDEYAP---EDIIEYDYEYGEAEYKEAESVTEGPTVTEETIA 296
Query: 553 QPQAQ--SPYQQ------QQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELS 604
Q +A +Q+ + Q AP +S P P + + + + + ++ S
Sbjct: 297 QTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNE-PNPVEEIFTEEYLTGEDYDSQRKNS 355
Query: 605 QDSFGSQAS----SAPSMTSSKGGQEDMN--LSLQSRPSSLPDLSGSIDDLPMGTEGALS 658
+D+ + + G+ D + +P+S P+ +P T+
Sbjct: 356 EDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFG-PGVPAETD-ITE 413
Query: 659 PGVSTSGISSSQGEQSNPA-----------QSPFSPHTSPHLPGIRGPSPSPVGSPASVA 707
++ G +G++ PA P P PG++GP+ P G P
Sbjct: 414 TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPGDPGD-- 470
Query: 708 QSRSGPLSPAAVPGNQMPPRPPS-------------GQSDSIMHPSMNQSSIAQDRGYMQ 754
GP +PG P PP + +I +I Q
Sbjct: 471 ---RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIAL 527
Query: 755 RNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQ 812
R P P + +PG P GG +G + G GPQG G GP G +
Sbjct: 528 RGPPGPMGLTGRPG-------PVGGPGSSGA----KGESGDPGPQGPRGVQGPPGPTGK- 575
Query: 813 PNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPN 871
P P A+ GM G G G G PG+P G H G R P GP
Sbjct: 576 PGKRGRPGAD-GGRGMPGEPGAKGDRG-FDGLPGLP-------GDKGHR--GERGPQGPP 624
Query: 872 MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPN-MNQGGMMGT-GPP 929
PPG + ++ + P G P G++G G P
Sbjct: 625 -------------GPPGDDGMRGEDGEIG-----------PRGLPGEAGPRGLLGPRGTP 660
Query: 930 YGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
G MAG+ P GP +MG G +P GL
Sbjct: 661 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701
Score = 45.8 bits (107), Expect = 4e-04
Identities = 71/258 (27%), Positives = 87/258 (33%), Gaps = 58/258 (22%)
Query: 7 PAAASSLGNPPPP----PP----SELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES 58
P + G P PP PP +E ++ E+ + EAG E G A
Sbjct: 1347 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406
Query: 59 EGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--PALNNN 116
EG G P P+G++ GA G G G G PG P LK G+ G + P L
Sbjct: 1407 EG-LRGIPGPVGEQGLPGA----AGQDGPPGPMGPPGL-PGLKGDPGSKGEKGHPGL-IG 1459
Query: 117 LTEPPGGGGGGSSDGV----GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172
L PPG G G+ G+P +P PA G P
Sbjct: 1460 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP------------------- 1500
Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPP-----PAP 227
PGL Q G G + GP D G P P S PP P P
Sbjct: 1501 ----GPPGLPGPQ--GPKGNKGSTGPAGQKGDSGLPG-------PPGSPGPPGEVIQPLP 1547
Query: 228 AYALSSPRGGTPGSGAAA 245
+ R T G A A
Sbjct: 1548 ILSSKKTRRHTEGMQADA 1565
Score = 40.8 bits (94), Expect = 0.014
Identities = 56/201 (27%), Positives = 67/201 (33%), Gaps = 13/201 (6%)
Query: 791 NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850
N G+YG +G Q G P L AG AG + P G G G PG P
Sbjct: 417 NGHGAYGEKG-----QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPG-DPG 469
Query: 851 GTLPPGRMSHASMGNRPYGPN-MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQ 909
PPGR P P M +P + G P ++ Q A+ A
Sbjct: 470 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ--ARIAL 527
Query: 910 NRPPGYPNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMM 968
PPG M G G G P G +G PQGP G G P
Sbjct: 528 RGPPG--PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585
Query: 969 GLGDVKLTPATKMNNKADGTP 989
G + P K + DG P
Sbjct: 586 GGRGMPGEPGAKGDRGFDGLP 606
Score = 34.3 bits (77), Expect = 1.3
Identities = 78/335 (23%), Positives = 100/335 (29%), Gaps = 70/335 (20%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ-IPPLPGM----------- 1179
PP PAG + GP Q + + GD PP P + +P PG
Sbjct: 443 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 502
Query: 1180 -SRSNSVGIQDAFNDGSDSTFQKRN----------SMTPNPGYQPSMNTSDMMGRMSYEP 1228
S+ ++ Q+A + + Q+ +T PG +S G
Sbjct: 503 GSKGPTISAQEA---QAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 559
Query: 1229 NKDPYGSM-RKAPGSDPFMSSGQGPNGGMGDPYSRAAG--------PGLGNVAMGPRQHY 1279
+ P G P P G +GG G P A PGL +
Sbjct: 560 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 619
Query: 1280 PYGGP----YDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334
P G P D +R E G IGP G P+ G+ P P Q
Sbjct: 620 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR----------GLLGPRGTPGAPGQPGMA 669
Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFL---- 1390
D G P G P P Q Q P+ P E P P L
Sbjct: 670 GVDGPPGPKGNMG-PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK--GPQGKPGLAGLP 726
Query: 1391 -------HSGMKMQKA-----GPPVPASHIA-PAP 1412
H G + Q GPP P I P P
Sbjct: 727 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP 761
Score = 34.3 bits (77), Expect = 1.3
Identities = 73/325 (22%), Positives = 102/325 (31%), Gaps = 58/325 (17%)
Query: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186
Q K PP P G + GPQ P + + E G PP P P Q LPG + G
Sbjct: 957 QGKTGPPGPGG---VVGPQGPTGETGPIGERGHPGPPGP---PGEQ--GLPG-----AAG 1003
Query: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246
+ A D ++ G+ G + + P
Sbjct: 1004 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP-------------- 1049
Query: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GPYDRVRTEPGIGPEGNMSTGA 1304
QGP G +G P R + G + + P + P G GP GP+G
Sbjct: 1050 ---QGPPGPVGSPGERGSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105
Query: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP--------------- 1349
Q + P SP + + + + S G++ G P
Sbjct: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK-GENGPPGPPGLQGPVGAPGIA 1164
Query: 1350 --SGSPFPSQQTTMYQQQQQVSS---PAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVP 1404
G P P Q M+ Q+ + P P P P+ + P + GPP P
Sbjct: 1165 GGDGEPGPRGQQGMFGQKGDEGARGFPGP-PGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1223
Query: 1405 ASHIAPAPVQPPMIRRDITFPPGSV 1429
P Q P PPGSV
Sbjct: 1224 P---GPRGPQGPNGADGPQGPPGSV 1245
Score = 34.3 bits (77), Expect = 1.3
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDL---KPPTPASTPHSQIPPLPGMS----RSNS 1184
PP P G QGP+ + ++ + GD PP P I PLP +S R ++
Sbjct: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1558
Query: 1185 VGIQ-DA------FNDGSDSTFQKRNSM 1205
G+Q DA ++DG + F NS+
Sbjct: 1559 EGMQADADDNILDYSDGMEEIFGSLNSL 1586
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 101 bits (251), Expect = 9e-21
Identities = 253/1051 (24%), Positives = 321/1051 (30%), Gaps = 162/1051 (15%)
Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75
PP PP S K Q ++ G + + GQ GPP LG Q
Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514
Query: 76 GAESNGGGGG--GGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDG 131
G + G G G G G PGA P K G+ P + + E G G
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574
Query: 132 VGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGG 191
G P LP P G+P G F + G +PGL L G
Sbjct: 575 PGTPGQDGLPGLPGPK---GEPGG-----------ITFKGERGPPGNPGLPGLPGNIGPM 620
Query: 192 LEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPA--PAYALSSP-RGGTPGS-GAAAAA 247
P GP + G N P + P P P ++ P + G PG+ G
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGN---PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677
Query: 248 GSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG 307
G P ++ G G G P G P P P + P A G
Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPPGPKGFPGI----PGPPGAPG 728
Query: 308 YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP--- 364
G G + GP KG A A G R P P
Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788
Query: 365 ----------GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ----------- 403
G G GQP P + G P P G P Q
Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP--PGPPGIPGPIGQPGLHGIPGEKG 846
Query: 404 QQGPPS----GPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ-QIPPYGQQG 458
GPP GP G PG P G+ P P + ++ G T+ ++ G G
Sbjct: 847 DPGPPGLDVPGPPGERGSPGIP-GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG 905
Query: 459 PSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPP 517
P G G G++ + Q QP + +P P P L S+
Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965
Query: 518 YSQQPSQP--PHQQSPAPY------PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569
+ P P P P Y P Q + Q PP + P Q P
Sbjct: 966 KGE-PGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024
Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629
+P PQ + PP GS P + KG + D
Sbjct: 1025 LKGTIGDMGFPGPQGVEG----------PPGPSGVPGQPGS-----PGLPGQKGDKGDPG 1069
Query: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQSPFSPHTS-- 686
+S LP L G P G G PG GI S G+ P P +P
Sbjct: 1070 IS----SIGLPGLPG-----PKGEPGL--PGYPGNPGIKGSVGDPGLPGL-PGTPGAKGQ 1117
Query: 687 PHLPGIRG----PSPSPVGSPASVA--QSRSGPLSPAAVPGNQMPP--RPPSGQSDSIMH 738
P LPG G P P + P GP+ PG PP + GQ D I
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ-DGIPG 1176
Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSPQ-----PGSALSPRQPSGGQIHTGMGSYQQNSM 793
P+ + Q P +P S + PG +P P G + G +
Sbjct: 1177 PAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKGEPGFHGFP-GVQ 1234
Query: 794 GSYGPQG----------GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQM 841
G GP G G GPQG G P + LP P G+ G G G
Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPP-GLPGNGGIKGEKGNP 1293
Query: 842 HGQPGIPPYGTLP-----------PGRMSHASMGNRPYGPNMANMPPQVG-SGMCPPPGG 889
GQPG+P L PGR M P P + P G SG+ PG
Sbjct: 1294 -GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV---PGS 1349
Query: 890 MNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM---GTGPPYGQGINSMAGMINPQGP 946
+ + + PPG P + ++ GPP G + G+ PQGP
Sbjct: 1350 AGPEGEPGLIG--------PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP 1401
Query: 947 PYSMGGTMANNSAGMAASPEMMGLGDVKLTP 977
G T G P G G K P
Sbjct: 1402 QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1432
Score = 95.1 bits (235), Expect = 6e-19
Identities = 208/882 (23%), Positives = 264/882 (29%), Gaps = 162/882 (18%)
Query: 60 GPAVGPPQPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAG------ 108
GP P Q + + + G N G G G G G PG P + S G G
Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL-PGIPGSKGEPGIPGIGL 708
Query: 109 ---PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAA 165
P P + PPG G G+ PP P GF P P +
Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768
Query: 166 AAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP 225
A+ + G P G GL+ GP+ + +G P P PP
Sbjct: 769 GALGPKGDRGFPGPP----GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP 824
Query: 226 APA-----------YALSSPRG----------GTPGS----GAAAAAGSKPPPSSSASAS 260
P + + +G G PG G A G PP S
Sbjct: 825 GPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884
Query: 261 SSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLN--------QLLTSPSSARGYQG 310
+ +S G MG GP G G P + P L L P+ +G +G
Sbjct: 885 KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944
Query: 311 YPGGDYSGGPQD----GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS 366
PG GP D G G+ G + Q P PG
Sbjct: 945 EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004
Query: 367 SGGGGQP-------LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP----QQGH 415
G G P L P + MG PQ G S G P P Q+G
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064
Query: 416 ------------------------GYPGQP-----YGSQTPQRYPMTMQGRAQSAMGGLS 446
GYPG P G P T + Q + G
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124
Query: 447 YTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505
T P P G GP G P HP Q PP + P Q P+ Q+
Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184
Query: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQ-PQAQSPYQQQQ 564
QP P Q P P P+ +P + P Q P
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPG-IPGNPGLPG--PKGEPGFHGFPGVQGP--PGP 1239
Query: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGG 624
P P P+ L P PQ + Q P P+ P + + G
Sbjct: 1240 PGSPGPA-LEGPKGNPGPQGPPGRPGPTGFQGLPGPE------------GPPGLPGNGGI 1286
Query: 625 QEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPH 684
+ + Q LP L G D P G +G +PG G++ +G+ P
Sbjct: 1287 KGEKGNPGQPGLPGLPGLKG--DQGPPGLQG--NPG--RPGLNGMKGDPGLPGV------ 1334
Query: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744
P PG++GPS P G P PG PP PP + PS
Sbjct: 1335 --PGFPGMKGPSGVP------------GSAGPEGEPGLIGPPGPP-----GLPGPSGQSI 1375
Query: 745 SIAQDRGYMQRNPQMPQYSSPQPG--SALSPRQPSGGQIHTG-MGSYQQNSMGSYGPQGG 801
I D G P QPG P+ P G TG G +N + + GG
Sbjct: 1376 IIKGDAG--------PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1427
Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843
+ G G P QP L P G+ G P G HG
Sbjct: 1428 RKG-DPGLPGQPGTRGLDGPPGPD-GLQGPPGPPGTSSVAHG 1467
Score = 94.4 bits (233), Expect = 1e-18
Identities = 243/1052 (23%), Positives = 324/1052 (30%), Gaps = 168/1052 (15%)
Query: 13 LGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKE 72
L P P + E+ Q+ + G R G++ G P G+
Sbjct: 314 LPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373
Query: 73 LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV 132
G + G G + GP P G G ++ PPG G + G+
Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL 433
Query: 133 GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192
PP A + PP+ +P P + + G + G G G
Sbjct: 434 PGPPGPAGPHI-PPSDEICEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG-- 488
Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGS-GAAAAAGS 249
+GP G P + +P + A A + P+G G PG+ GA GS
Sbjct: 489 --ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA---TGPKGLPGIPGAPGAPGFPGS 543
Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSAR- 306
K P + G +G G G GTP P L P
Sbjct: 544 KGEPGDILTFPGMKGD-----KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598
Query: 307 -------GYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH 359
G G PG + GP G G GP + A G +
Sbjct: 599 KGERGPPGNPGLPGLPGNIGPM-GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657
Query: 360 APMSPGSSGGGGQP-------LARTP----QPSSPMDQMGKMRPQPYGGTNPYSQQQGPP 408
PG G G P L P QP P K P G P GPP
Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPP 712
Query: 409 SGPQQGHGYPGQPYGSQTPQRYPMT----------MQGRAQSAMGGLSYTQQIP------ 452
GP+ G PG P TP R + +G A+ G +P
Sbjct: 713 -GPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771
Query: 453 -PYGQQG-PSGYGQQGQTPYYNQQSPH----PQQQQPPYS---------QQPPSQTPHAQ 497
P G +G P G G+T P P Q P Q PP
Sbjct: 772 GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP----APYPSQQSTTQQHPQSQPPYSQ 553
P Q P + PP P P + SP AP P + P
Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891
Query: 554 PQAQSPY-QQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612
P + P P P + ++ P + Q Q P P
Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ---GQPGLPGP------------ 936
Query: 613 SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL-SPGV-STSGISSSQ 670
T KG + + LP G +D +G++G PG+ G+S +
Sbjct: 937 ------TGEKGSKGE---------PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981
Query: 671 GEQSNPAQSPFSPHTS--PHLPGIRGPSPSP--VGSPASVA----------------QSR 710
G Q P P P S P LPG GP +P G P + Q
Sbjct: 982 GYQGLPG-DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040
Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSA 770
GP P+ VPG P P GQ P ++ + G + P +P Y PG
Sbjct: 1041 EGPPGPSGVPGQPGSPGLP-GQKGDKGDPGISSIGLPGLPG-PKGEPGLPGYPG-NPGIK 1097
Query: 771 LSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG--GYPRQPNYNALPNANYPSAGM 828
S P + G+ Q + + G GP+G G P P G+
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP-------------GL 1144
Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPG 888
G P+G GG GQPG PPG P P Q G G PPG
Sbjct: 1145 PGEPGPVGGGGH-PGQPG-------PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196
Query: 889 --GMNRKTQETAVAMHVAANSIQNRPPGYPNMNQ-GGMMG-TGPP--YGQGINSMAGMIN 942
G++ + + + + N P G P + G+ G GPP G + G
Sbjct: 1197 LPGLSGQKGDGGLP-GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255
Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLGDVK 974
PQGPP G T G P + G G +K
Sbjct: 1256 PQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIK 1287
Score = 73.2 bits (178), Expect = 3e-12
Identities = 222/979 (22%), Positives = 289/979 (29%), Gaps = 197/979 (20%)
Query: 76 GAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133
G++ + G G G G PG E P L G GP PG G DG+
Sbjct: 35 GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGP-----------PGPRGQKGDDGIP 83
Query: 134 APPHSAAAALPPPAYGF-------GQP-YGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQ 185
PP PP GF G P + +P + G SPG LQ
Sbjct: 84 GPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQ 143
Query: 186 SGGGG-GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGS--- 241
G G+ G + P + N YP P L P G PG
Sbjct: 144 GPPGPPGIPGMKGEPGSIIMSSLPGPKGNP------GYPGPPGIQGLPGPTG-IPGPIGP 196
Query: 242 -GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300
G G PP + +F + G G G G P P + +
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPK-GEKGEQGLQ----GPPGPPGQISEQKRPI 251
Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360
+G QG PG GP +GP G + +
Sbjct: 252 DVEFQKGDQGLPG---DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308
Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420
P PG G G P P Q G P G G G + G PG
Sbjct: 309 PGIPGLPGDPGYP--GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366
Query: 421 PY--------GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472
P G Q P P G + + G +GP G G P +
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLD 425
Query: 473 QQSPHPQQQQPPYSQQP--PSQTPHAQPSYQQQPQSQPPQ-LQSSQ-------------- 515
Q P PP P P +P P S + LQ Q
Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCI 485
Query: 516 -PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA-PSTL 573
S P QP P P S Q+ + Q + P+ P P P P +
Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGL-PGIPGAPGAPGFPGSK 544
Query: 574 SQQA---AYPQPQSQQSQQTAYSQQRFPP-PQELSQDSFGSQASSAPSMTSSKGGQEDMN 629
+ +P + + + + P P QD P + KG +
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL-------PGLPGPKGEPGGIT 597
Query: 630 LSLQSRPSSLPDLSGSIDDL-PMGTEGALSPG-VSTSGISSSQGEQSNPAQ--------S 679
+ P P L G ++ PMG G PG V GI QG NP Q
Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI---QGVAGNPGQPGIPGPKGD 654
Query: 680 PFSPHTSPHLPGIRGPS-----------------------PSPVGSPASVAQSRSGPLSP 716
P T P PG+ G P G P GP P
Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP 714
Query: 717 AAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPR 774
PG PP P R ++ P P + P +PG AL P
Sbjct: 715 KGFPGIPGPPGAPG----------------TPGRIGLEGPPGPPGFPGPKGEPGFAL-PG 757
Query: 775 QPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGI 832
P G+ ++ G+ GP+G G GP G P + + LP G G +
Sbjct: 758 PPGP----PGLPGFK----GALGPKGDRGFPGPPGP-PGRTGLDGLP-------GPKGDV 801
Query: 833 NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGS-GMCPPPGGMN 891
P G G M G PG+P G P P +P +G G+ PG
Sbjct: 802 GPNGQPGPM-GPPGLPGIGVQGP--------------PGPPGIPGPIGQPGLHGIPG--- 843
Query: 892 RKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMG 951
+ PG P G+ GPP +G + G P GPP S G
Sbjct: 844 -----------------EKGDPGPP-----GLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881
Query: 952 GTMANNSAGMAASPEMMGL 970
++G + MG+
Sbjct: 882 LPGKAGASGFPGTKGEMGM 900
Score = 65.9 bits (159), Expect = 4e-10
Identities = 234/1043 (22%), Positives = 312/1043 (29%), Gaps = 218/1043 (20%)
Query: 5 VAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVG 64
+ P L PP PP K G E+GE Q +GP G
Sbjct: 194 IGPPGPPGLMGPPGPPGLPGPKGNM-------GLNFQGPKGEKGE------QGLQGPP-G 239
Query: 65 PP-------QPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAGPRPA 112
PP +P+ E Q G + G G G G G PG E K G G R
Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK 299
Query: 113 LNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172
PG G G+ P P Y G+P GR
Sbjct: 300 --------PGKDGENGQPGIPGLPGD-------PGYP-GEP-GRDGEKGQKGDT------ 336
Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYP--PPAPAYA 230
G PGL + G G + G + N G P + +P P P P A
Sbjct: 337 -GPPGPPGLVIPRPGTGITI----GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391
Query: 231 LSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG------ 284
+ P G G G + PP S + GA G GP G
Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG----QPGAPGLPGPPGPAGPHIPPS 447
Query: 285 ------GTPQPTATPTLNQLLTSPSSARGYQGYP-----GGDYSGGPQDGGAGKGPADMA 333
G P P +P ++ L +G +G G SG P G P
Sbjct: 448 DEICEPGPPGPPGSPG-DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506
Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393
S + A A+G P PG+ G G P ++ +P + G +
Sbjct: 507 SLGFPGQKGEKGQAGATG-----PKGLPGIPGAPGAPGFPGSKG-EPGDILTFPGMKGDK 560
Query: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453
G+ G P P Q G PG P P+ P + + + G +P
Sbjct: 561 GELGSPGAPGLPGLPGTPGQD-GLPGLP----GPKGEPGGITFKGERGPPGNPGLPGLPG 615
Query: 454 -YGQQGPSGYGQQGQTPYYNQQ--SPHPQQQQPPYSQQPPSQ--TPHAQPSYQQQPQSQP 508
G GP G+G G Q + +P Q P + P Q T +P P
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675
Query: 509 PQLQSSQPPYSQQPSQP--PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ 566
P QP P P + P P+ P P
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG---------- 725
Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626
AP T + P FP P+ G+
Sbjct: 726 --APGTPGRIGLEGPP----------GPPGFPGPK----------------------GEP 751
Query: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG-----VSTSGISSSQGEQS-NPAQSP 680
L P LP G++ P G G P G+ +G+ N P
Sbjct: 752 GFALPGPPGPPGLPGFKGALG--PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809
Query: 681 FSPHTSPHLPGI--RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH 738
P P LPGI +GP P P G P + Q +PG + P PP
Sbjct: 810 MGP---PGLPGIGVQGP-PGPPGIPGPIGQP-----GLHGIPGEKGDPGPPG-------- 852
Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPRQPSGGQIHTGMGSYQQNSMGSY 796
++ +RG +P +P P PGS P + G MG
Sbjct: 853 --LDVPGPPGERG----SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE-----MGMM 901
Query: 797 GPQGGQYGPQGGYPRQPNYNALPNANYPSA--GMAGGINPMGAGGQMHGQPGIPPYGTLP 854
GP G GP G P + +P G G P G G G+PG+P P
Sbjct: 902 GPPGPP-GPLG----IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK-GEPGLPG----P 951
Query: 855 PGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRP-- 912
PG P PN+ + G P G++ Q P
Sbjct: 952 PG----------PMDPNLLGSKGEKGEPGLPGIPGVS------------GPKGYQGLPGD 989
Query: 913 PGYPNMN-QGGMMGT-GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970
PG P ++ Q G+ G GP G+ G+I P G ++G G+ P G+
Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049
Query: 971 GDVKLTPATKMNNKADGTPKTES 993
+P G P S
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISS 1072
Score = 36.2 bits (82), Expect = 0.34
Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 7/127 (5%)
Query: 53 AAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPR 110
+AG E E +GPP P G G G G G G PG + P + G GP
Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408
Query: 111 ----PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF-GQPYGRSPSAVAAAA 165
N L G GG G+ P + PP G G P S+VA
Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGF 1468
Query: 166 AAVFHQQ 172
H Q
Sbjct: 1469 LITRHSQ 1475
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 100 bits (250), Expect = 1e-20
Identities = 196/917 (21%), Positives = 299/917 (32%), Gaps = 137/917 (14%)
Query: 111 PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPP---PAYGFGQPYGRSPSAVAAAAAA 167
PAL+ + P + G+ A P A PP P G P SP AA
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAP 227
GG +P S G P A P P+ + P+ P P P
Sbjct: 969 TPPSPKGGPATP------SPKGAPTPPAATP---------PSPKGGPATPSPKGAPTP-P 1012
Query: 228 AYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTP 287
A SP+G +P + S PP ++ S S ++ + G P+ P
Sbjct: 1013 AVTPPSPKG-SPAATPFPKGASTPPAATPPSPKGSPAATPLPK------GAPTTPAATLP 1065
Query: 288 QPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAA 347
P P L +P+ P G P GA PA A
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGG-PATPSPKGAPMPPA-------------ATPP 1111
Query: 348 AASGGAQQRSHH-APMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGG--TNPYSQQ 404
+ GG H AP +P ++ + TP P P P GG T P
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP---P 1168
Query: 405 QGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQ 464
+G P+ P P + +P+ P T S GGL+ P + P+
Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA-----TPSPKGAPT---- 1219
Query: 465 QGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS- 523
TP SP P P TP A P + + PP + PP + PS
Sbjct: 1220 ---TPAATPPSPKGGLATPSPKGAPT--TPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
Query: 524 -----QPPHQQSPAPYPSQQSTTQQHPQSQPPY---SQPQAQSPYQQQQPQQPAPSTLSQ 575
PPH+ +P P + + P + PP + P A P + P P P
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
Query: 576 QAAY--PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQ 633
A P P+ + + P S++ + P+ T S G M
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG-----PTPPAATPSHKGGPAMTPPSP 1389
Query: 634 SRPSSLPDLSGSIDD---LPMGTEGALSPGVSTSGISS-SQGEQSNPAQSPFSPHTSPHL 689
R ++P G +P+ + A + V+ G ++ S+G+ + PA +P S +P
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP-- 1447
Query: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749
+ +P G PA+ + S+ P PA P + P PP+ + + +
Sbjct: 1448 -----ATSAPKGGPATPS-SKGDPTLPAVTPPS--PKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 750 RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGY 809
G +P P + S R P I + + + P+ P
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDP----IAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Query: 810 PRQPNYNALPNANY----PSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGN 865
P A+P PS+ A P G P P L P ++ S
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASS-PPAVTPSTYKGAPS--PKELLIPPAVTSPSPKE 1612
Query: 866 RPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMG 925
P P + P+ G P G T + V +S+++ P
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKG--------TPTSPPVTPSSLKDSPT------------ 1652
Query: 926 TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKA 985
+P MG T+ S G+ A L +V + PA +
Sbjct: 1653 ----------------SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696
Query: 986 DGTPKTESKSKKSSSST 1002
+ ++KKSS+++
Sbjct: 1697 TAPTRKGPQTKKSSATS 1713
Score = 99.4 bits (246), Expect = 3e-20
Identities = 184/832 (22%), Positives = 268/832 (32%), Gaps = 162/832 (19%)
Query: 7 PAAASSLGNPPPP---PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAV 63
PA S G P PP PPS G AA AA +G
Sbjct: 1000 PATPSPKGAPTPPAVTPPSP-----------KGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGG 123
P P G A GG S G P + GP PP
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 124 GGGGSSDGVGAPPHSAA----AALPP-PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQS 178
G+ PPH A AA PP P G P P AA GG +
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP---PPKGAPTTPAATPPSPKGGLAT 1165
Query: 179 PGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG- 237
P G P A P P+ + P PA SP+GG
Sbjct: 1166 P------PPKGAPTTPAATPPSPKGGLATPSPKG----------APTTPAATPPSPKGGL 1209
Query: 238 -TPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTL 295
TP A + PPS ++ S A A PS GG TP P PT
Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP---PSPKGGPATPPPKGAPT- 1265
Query: 296 NQLLTSPSSARG------YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAA 349
+P S +G ++G P P G GPA + GA AA +
Sbjct: 1266 -PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG---GPATSPPK--GAPTPPAATPPS 1319
Query: 350 SGGAQQRSHHAPMSPGSSGGGGQPLARTPQP--------SSPMDQMGKMRPQPYGGTNPY 401
G+ P +P G P P P ++P + G P G P
Sbjct: 1320 PKGS-------PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372
Query: 402 ----SQQQGP---PSGPQQGHGYPGQ----------PYGSQTPQRYPMTMQGRAQSAMGG 444
S + GP P P++G P P + P+T +G A + G
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 445 LSYTQQIPPYGQQGPSGYGQQG--QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502
L+ P ++ P+ +G TP ++ P PP ++PP+
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPS-SKGDPTLPAVTPPSPKEPPA----------- 1480
Query: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562
P Q+ +S P + P +P P+ + P+ P +P +
Sbjct: 1481 -----PKQVATSS-----SPKKAPATPAPMGAPTLPAVIPSSPKEVPA-------TPSSR 1523
Query: 563 QQPQQPAPSTLSQQAAY---PQPQSQQSQQTAYSQQR---FPPPQELSQDSFGSQASSAP 616
+ P P + LS++ P+ T S ++ P P+E +ASS P
Sbjct: 1524 RDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583
Query: 617 SMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNP 676
++T S + P E + P V++ S + + P
Sbjct: 1584 AVTPS-----------------------TYKGAPSPKELLIPPAVTSP---SPKEAPTPP 1617
Query: 677 AQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMP--------PRP 728
A +P SP P P +G SP +P+S+ S + P S G +P +
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677
Query: 729 PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780
P+ + ++ P+ + I ++ PQ + S+ P P +G +
Sbjct: 1678 PTALKEVLVAPAPESTPII--TAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727
Score = 97.8 bits (242), Expect = 1e-19
Identities = 186/839 (22%), Positives = 265/839 (31%), Gaps = 165/839 (19%)
Query: 224 PPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283
PP+P A +P TP S G PP + + S + F ++ G
Sbjct: 858 PPSPKGA-PTPSAVTPLS----PKGVTLPPKETPTPSVVNLPFPKE-------------G 899
Query: 284 GGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGG--------AGKGPADMASQ 335
TP P P L+ +SP AR G S P+ + KG S
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPY 395
W AA + GG P +P G P A P P G P P
Sbjct: 960 KWAPTPPAATPPSPKGG--------PATPSPKGAPTPPAATPPSPKG-----GPATPSPK 1006
Query: 396 GGTNPYSQQQGPPSGPQQGHGYP---------------GQPYGSQTPQRYPMTMQGRAQS 440
G P + P G +P G P + P+ P T S
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 441 AMGGLSYTQ---------QIPPYGQQGPSGYGQQG--QTPYYNQQSPHPQQQQPPYSQQP 489
GG + PP + GP+ +G P SP PP+ P
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Query: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
TP A P + + PP + P + PS P P P TT P + P
Sbjct: 1127 T--TPAATPPSPKGGLATPPPKGAPTTPAATPPS--PKGGLATPPPKGAPTT---PAATP 1179
Query: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609
P + +P + P PA + S + P + + T + P + G
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239
Query: 610 SQASSAPSMTSSKGGQEDMNLSLQSRPSSL--PDLSGSIDDLPMGTEGALSPGVSTS--- 664
+ + A + S KGG P + P L G + P +GA +P V T
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH--KGAPNPAVVTPPSP 1297
Query: 665 ----GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS-------PSPVGSP---ASVAQSR 710
S +G + PA +P SP SP P +G PSP G+P A+ S+
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSA 770
GP +P++ G P PS + M P + R P +P A
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK-----------RGPAIPSPKGDPTSPA 1406
Query: 771 LSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAG 830
+ P P + G+ P G P P +L A SA G
Sbjct: 1407 VIPLSPKKAP------ATPVTREGAATPSKGDLTPPAVTPV-----SLKKAPATSAPKGG 1455
Query: 831 GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPP---- 886
P G P +P PP P P QV + P
Sbjct: 1456 PATPSSKG-----DPTLP--AVTPPS-------------PKEPPAPKQVATSSSPKKAPA 1495
Query: 887 -PGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQG 945
P M T + S P P+ + + T A +++ +
Sbjct: 1496 TPAPMGAPTLPAVIP------SSPKEVPATPSSRRDPIAPT-----------ATLLSKKT 1538
Query: 946 PPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTT 1004
P T+A A + P M + K TPA +A TP ++ S + + +T
Sbjct: 1539 P-----ATLAPKEALI---PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589
Score = 97.1 bits (240), Expect = 2e-19
Identities = 182/828 (21%), Positives = 275/828 (33%), Gaps = 117/828 (14%)
Query: 225 PAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284
P+P SP+ P + +A P + S+ S +SF + + G S A
Sbjct: 794 PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853
Query: 285 GTPQPTA---TPTLNQLLTSPSSARGYQGYPGGDYSGG------PQDGGAGKGP--ADMA 333
+P P + PT + + +P S +G P + P++G A P A
Sbjct: 854 HSPTPPSPKGAPTPSAV--TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911
Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSS-PMDQMGKMRP 392
S + A A A G P SP G P A P P P K P
Sbjct: 912 SMTSSSPKKARATPAPKG--------IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Query: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY--PMTMQGRAQSAMGGLSYTQQ 450
P T P +G P+ P P G+ TP P G A + G
Sbjct: 964 TPPAATPP--SPKGGPATPS--------PKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 451 IPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510
+ P PS G TP+ P+ P + PPS P P+ P+ P
Sbjct: 1014 VTP-----PSPKGSPAATPF-------PKGASTPPAATPPS--PKGSPAATPLPKGAPTT 1059
Query: 511 LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570
++ P P+ P + +P P P + PP + +P + P PA
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTP-----------PAATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630
+ S + P + + T + P + G+ + A + S KGG
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT--- 1165
Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSP-GVSTSGISSSQGEQS-----NPAQSPFSPH 684
P P + P G SP G T+ ++ + +P +P +P
Sbjct: 1166 ---PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222
Query: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744
+P P +PSP G+P + A + P A P + P PP+ S+ +
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL------KG 1276
Query: 745 SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG--PQGGQ 802
+A NP + SP+ G A SP P G T + + GS G P G
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAP--TPPAATPPSPKGSPGTPPPKGA 1332
Query: 803 YGPQGGYPRQPNYNALPNANYPSA-------GMAGGINPMGAGGQMHGQPGIPPYG---- 851
P P P A PS+ G P A G P + P
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
Query: 852 -TLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQN 910
+P + S P P A P G P G T V++ A + +
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT--S 1450
Query: 911 RPPGYPNMNQGGMMGTGPPYGQGINSMAGMI--NPQGPPYSMGGTMANNSAGMAASPEMM 968
P G G P +G ++ + +P+ PP +++ A+P M
Sbjct: 1451 APKG----------GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
Query: 969 GL--------GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKI 1008
G K PAT + + P SKK+ ++ E +
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548
Score = 94.0 bits (232), Expect = 1e-18
Identities = 150/685 (21%), Positives = 212/685 (30%), Gaps = 112/685 (16%)
Query: 96 AEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYG 155
A P K + P+ A PP GG ++ P AA P P G P
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK---GGPAT 979
Query: 156 RSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSY 215
SP AA GG +P
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGA------------------------------- 1008
Query: 216 YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMG 275
P A PP+P G+P + S PP ++ S S ++ +
Sbjct: 1009 -PTPPAVTPPSPK--------GSPAATPFPKGASTPPAATPPSPKGSPAATPLPK----- 1054
Query: 276 GGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQ 335
G P+ P P P L +P+ P G GPA + +
Sbjct: 1055 -GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG-------------GPATPSPK 1100
Query: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPY 395
AA + G A AP +P ++ + TP P P P
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160
Query: 396 GG--TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453
GG T P +G P+ P P + +P+ P T S GGL+ P
Sbjct: 1161 GGLATPP---PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA-----TP 1212
Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513
+ P+ TP SP P S + TP A P + + PP +
Sbjct: 1213 SPKGAPT-------TPAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGPATPPPKGA 1263
Query: 514 SQPPYSQQPS------QPPHQQSPAPYPSQQSTTQQHPQSQPPY---SQPQAQSPYQQQQ 564
PP + PS PPH+ +P P + + P + PP + P A P +
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Query: 565 PQQPAPSTLSQQAAYPQPQ------------SQQSQQTAYSQQRFPPPQELSQDSFGSQA 612
P P P A P S + T S + P P + G A
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383
Query: 613 SSAPS-----MTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667
+ PS S G + P P + + ++G L+P T
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
Query: 668 SSQGEQSNPAQSPFSPHT--SPHLPGIRGPSPSPVGSPASVAQSRS---GPLSPAAVPGN 722
S P P +P + P LP + PSP +P VA S S P +PA +
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503
Query: 723 QMPPRPPSGQSDSIMHPSMNQSSIA 747
+P PS + PS + IA
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIA 1528
Score = 73.6 bits (179), Expect = 2e-12
Identities = 268/1316 (20%), Positives = 409/1316 (31%), Gaps = 208/1316 (15%)
Query: 207 FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSF 266
FP + P P +PA A + + AA P S S+S
Sbjct: 526 FPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLS 585
Query: 267 AQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAG 326
+ G P G +P ++ T + S +S Y G D S GP +
Sbjct: 586 PEATLAKKSLGEPLPIG----KPASSMTSPLGVNSSASVIKTDSYAGPD-SAGPLLKSSL 640
Query: 327 KGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS-------------------- 366
P A A A A A G + + +P G+
Sbjct: 641 ITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPL 700
Query: 367 --SGGGGQPLARTPQPS-SPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQ----GHGYPG 419
+ P+A +PQ + +P+ + P +P G P G ++ H
Sbjct: 701 VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSAL 760
Query: 420 QPYGSQTPQRYPMTMQGRAQSAM--GGLSYTQQIP--------PYGQQGPSGYGQQG-QT 468
P S +P+ P G + +A G L+Y P P ++ P+ G G T
Sbjct: 761 APVAS-SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT 819
Query: 469 PYYNQQSP---------------------------HPQQQQPPYSQQPPSQTPHAQPSYQ 501
P N SP P P + P + TP +
Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879
Query: 502 QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP-PYSQPQAQSPY 560
P+ P + P + P+ P +Q+PA S S++ + ++ P P P + SP
Sbjct: 880 LPPKETPTPSVVNLPFPKEGPATPAPKQAPAL--SMTSSSPKKARATPAPKGIPASPSPK 937
Query: 561 QQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTS 620
P P + A P P+ + A P + G+ A + S
Sbjct: 938 GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS--PKGGPATPSPKGAPTPPAATPPS 995
Query: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGA--LSPGVSTSGISSSQGEQSNPAQ 678
KGG + P P P G+ A G ST ++ + +PA
Sbjct: 996 PKGGPATPS------PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049
Query: 679 SPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP----GNQMPPRPPSGQSD 734
+P P +P P PSP G PA+ + + P PAA P G P P
Sbjct: 1050 TPL-PKGAPTTPA--ATLPSPKGGPATPSL-KGAPTPPAATPPSPKGGPATPSPKGAPMP 1105
Query: 735 SIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIH-TGMGSYQQNSM 793
P + +A + P P + P P L+ P G + +
Sbjct: 1106 PAATPPSPKGGLATPPH--KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 794 GSYGPQGGQY-------GPQGGY--PRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844
+ P+G P+GG P P A PS GG+ G
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP--KGGLATPSPKGAPTTP 1221
Query: 845 PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVA 904
PP P G ++ S P P A P G PPP G T ++
Sbjct: 1222 AATPPS---PKGGLATPSPKGAPTTP-AATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 905 ANSIQNRPPGYPNM------NQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNS 958
+ ++ G PN + G T PP G A +P+G P GT
Sbjct: 1278 LATPPHK--GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP----GTPPPKG 1331
Query: 959 AGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018
A + PAT ++K T + + ++T +++ G P
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK---------GGP 1382
Query: 1019 ERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELAT 1078
A T +P+ P + +S K+ T V RE A
Sbjct: 1383 ----------AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA-TPVT-----REGAA 1426
Query: 1079 NLNVGTSSSAAS---SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSP 1135
+ G + A SLKK A +G P ++ + P + PPSP
Sbjct: 1427 TPSKGDLTPPAVTPVSLKK-------APATSAPKGGPATP----SSKGDPTLPAVTPPSP 1475
Query: 1136 AGSGSMQGPQTPQSTSSSMAEGGDLKPPT-PASTPHS--QIPPLPGMSRSNSVGIQDAFN 1192
+ + T S + A + PT PA P S ++P P R +
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 1193 DGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252
+ +T + ++ P PS P K P K + P P
Sbjct: 1536 KKTPATLAPKEALIPPAMTVPS-------------PKKTPAIPTPKEAPATPSSKEASSP 1582
Query: 1253 NGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQ--PNLM 1310
Y A P + P P T P PE +T AP+ P
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS--PEKGPATPAPKGTPTSP 1640
Query: 1311 PSNPDSGMYSPSR-----------YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQT 1359
P P S SP+ P + ++ + + P +P + T
Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPT 1700
Query: 1360 TMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQP 1415
Q ++ S+ +P P + + SK P S +APAP+ P
Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPL----------------STVAPAPLLP 1740
Score = 61.2 bits (147), Expect = 1e-08
Identities = 205/1008 (20%), Positives = 312/1008 (30%), Gaps = 201/1008 (19%)
Query: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPY 560
Q+ Q+ P L+ + P+S + ++ P P Q+ + P Q S P+
Sbjct: 529 QKDLQTVPASLEGA--PFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEI---- 582
Query: 561 QQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTS 620
P P + + P P + + + DS+ S+ P + S
Sbjct: 583 ----PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKS 638
Query: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQS- 679
S + ++ + P D +G GT + + S +++P +
Sbjct: 639 SL-----ITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEG 693
Query: 680 -----PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPR---PPSG 731
P P S + P +PSP + A +A P P +VP +PP P +
Sbjct: 694 TLTTLPLVPTASENCP----VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTK 749
Query: 732 QSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQN 791
+ D I H S P SSP+ P + SG
Sbjct: 750 KVDGISHTSA----------------LAPVASSPKE----CPTEDSGASATASSKGTLTY 789
Query: 792 SMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ------- 844
S P G PQ P +A P+ P ++ ++P+ A
Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDT--PIGNLSSPVSPVEASFLPENSLSFQGSK 847
Query: 845 --PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMN----RKTQETA 898
P T P + + P P +PP+ P P +N ++ T
Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE----TPTPSVVNLPFPKEGPATP 903
Query: 899 VAMHVAANSIQNRPPGYPNMNQG--GMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMAN 956
A S+ + P G+ + P G A +P+G P A
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP-------AT 956
Query: 957 NSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGG 1016
S A +P K PAT A P S K +T + + G
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK---------G 1007
Query: 1017 EPERKMWVDRYLAFTEEKAMGM---TNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKW 1073
P A T G T P P + K
Sbjct: 1008 APTPP-------AVTPPSPKGSPAATPFPKGASTPP---------------AATPPSPKG 1045
Query: 1074 RELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPP 1133
AT L G ++ A++L +G P + A + P PP
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSP-------------KGGPATPSLKGAP----TPPAATPP 1088
Query: 1134 SPAGSGSMQGPQ----TPQSTSSSMAEGGDLKPP------TPASTPHS-----QIPPLPG 1178
SP G + P+ P +T S +GG PP TPA+TP S PP G
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPS-PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG 1147
Query: 1179 MSRSNSV-------GIQDAFNDGSDST------FQKRNSMTPNPGYQPSMNTSDMMGRMS 1225
+ + G+ G+ +T K TP+P P+ +
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207
Query: 1226 YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPY 1285
P G+ + P G G P + AA P + GP P G P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP--PSPKGGPATPPPKGAPT 1265
Query: 1286 DRVRTEPGIGPEGNMST----GAPQPNLM-PSNPDSGMYSPSRYPPQQQQQQQQRHDSYG 1340
T P + +G ++T GAP P ++ P +P G P+ PP+
Sbjct: 1266 PPAATPPSL--KGGLATPPHKGAPNPAVVTPPSPKGG---PATSPPKGAPTPPA------ 1314
Query: 1341 NQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAG 1400
+T +P GSP AP P P SP +P L + K G
Sbjct: 1315 ---ATPPSPKGSP-----------GTPPPKGAPTP-PAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 1401 PPVPASHIAPAP------------VQPPMIRRDITFPPGSVEATQPVL 1436
P P+S P P + PP +R P + T P +
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Score = 48.9 bits (115), Expect = 5e-05
Identities = 82/386 (21%), Positives = 122/386 (31%), Gaps = 70/386 (18%)
Query: 1113 PPPDIFAAADSKK---SQPKIQPPSPAGSGSMQGPQ----TPQSTSSSMAEGGDLKPPTP 1165
P P A S K + P PPSP G + P+ TP +T S G PP
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262
Query: 1166 ASTPHSQIPPL--------PGMSRSNSVGIQDAFNDGSDSTFQKRNSMTP---------- 1207
A TP + PP P N + G +T + + TP
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
Query: 1208 NPGYQPSMNTSDMMGRMSYEPNKDPY--GSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAG 1265
+PG P P P + + G SS +GP P S G
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP-SHKGG 1381
Query: 1266 PGL--GNVAMGPRQHYPYGGPYDRVRTEPGIGP-EGNMSTGAPQPNLMPSNPDSGMYSPS 1322
P + + GP P G P T P + P + P + P G +P
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDP-----TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPP 1436
Query: 1323 RYPPQQQQQQQQRHDSYGNQFS------------TQGTPSGSPFPSQQTTMYQQQQQVSS 1370
P ++ G + T +P P P Q T ++ ++
Sbjct: 1437 AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 1371 PAPL------------PRPMENRTSPSKSPFLHSGMKMQKAGPP--------VPASHIAP 1410
PAP+ P+ + S + P + + K P +P + P
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 1411 APVQPPMI--RRDITFPPGSVEATQP 1434
+P + P I ++ P S EA+ P
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSP 1582
Score = 33.1 bits (74), Expect = 2.9
Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 40/215 (18%)
Query: 508 PPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQ 567
P + + P Q+ QP + + P S S T QP + P SP PQQ
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTA--ALGQPGPTLPPPCSP----APQQ 55
Query: 568 PAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQED 627
S +Q + +P P + A + P PQ S ++ P T+ +
Sbjct: 56 CPLSAANQASPFPSPST-----IASTPLEVPFPQ-------SSSGTALPLGTAPEA---- 99
Query: 628 MNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTS--GISSSQGEQSNPAQSPFSPHT 685
P+ LP+L G + SP ++ + G SS + A +P S
Sbjct: 100 --------PTFLPNLIG--PPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQK 149
Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720
S P P+ + SP SVA + SG + + P
Sbjct: 150 SSAFP------PNLLTSPPSVAVAESGSVITLSAP 178
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 100 bits (249), Expect = 1e-20
Identities = 233/985 (23%), Positives = 308/985 (31%), Gaps = 171/985 (17%)
Query: 37 GEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGG--GGAGSGGGP 94
GE A A G E VG P P G DG+ G G G AG G P
Sbjct: 199 GEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFP 258
Query: 95 GAEPDLKN---SNGNAGPR-----------PALNNNLTEPPGGGGGGSSDGVGAPPHSAA 140
GA P K + GNAGP P L+ + P G G + GA
Sbjct: 259 GA-PGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGA------ 311
Query: 141 AALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEP-YAGPQ 199
A LP A G P R AA A + G+ P + +SG G EP AGPQ
Sbjct: 312 AGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG--EPGSAGPQ 369
Query: 200 QNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASA 259
PP P S G +G A +AG PP S
Sbjct: 370 G-----------------------PPGP----SGEEGKRGPNGEAGSAGPPGPPGLRGSP 402
Query: 260 SSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGG 319
S A R G MG G A G P+ RG P GD +G
Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASG-----------------PAGVRG----PNGD-AGR 440
Query: 320 PQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP-LARTP 378
P + G GP + A G R P G +G G+P P
Sbjct: 441 PGEPGL-MGPRGLPGSPGNIGPAGKEGPVGLPGIDGR----PGPIGPAGARGEPGNIGFP 495
Query: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
P P GK + + G + +G P GP +G G P G Q Q G+
Sbjct: 496 GPKGPTGDPGKNGDKGHAG---LAGARGAP-GPDGNNGAQGPP-GPQGVQ------GGKG 544
Query: 439 QSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497
+ G Q +P G GP+G G+ G+ + + P P + PP ++ A
Sbjct: 545 EQGPPGPPGFQGLP--GPSGPAGEVGKPGERGLHGEFG-LPGPAGPRGERGPPGESGAAG 601
Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP---PYSQP 554
P + P S+ PS PP P S P P +
Sbjct: 602 P---------------TGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERG 646
Query: 555 QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS 614
A P + + +P L + P + A P P + D + A+
Sbjct: 647 AAGIPGGKGEKGEPG---LRGEIGNPGRDGARGAPGAVGA---PGPAGATGDRGEAGAAG 700
Query: 615 APSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALSPGVSTSGISSSQGEQ 673
+G + + P+ +G+ G GA P +G+ G
Sbjct: 701 PAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGP-KGENGVVGPTGPV 759
Query: 674 SNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQS 733
A P P+ P G RG P + A R+GP P+ + G PP P
Sbjct: 760 G--AAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAG--K 815
Query: 734 DSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSM 793
+ + P +Q + + P PG A + PSG
Sbjct: 816 EGLRGPRGDQGPVGRTGEVGAVGP---------PGFA-GEKGPSG-------------EA 852
Query: 794 GSYGPQGGQYGPQG--------GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP 845
G+ GP G GPQG G P LP AG G P+G G
Sbjct: 853 GTAGPPGTP-GPQGLLGAPGILGLPGSRGERGLPGV----AGAVGEPGPLGIAG------ 901
Query: 846 GIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-SGMCPPPGGMNRKTQETAVAMHVA 904
PP PPG + + P P G G PG + + A
Sbjct: 902 --PPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA 959
Query: 905 ANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAAS 964
A + P P G TGP G G P GP G G
Sbjct: 960 AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGL 1019
Query: 965 PEMMGLGDVKLTPATKMNNKADGTP 989
P + G ++ P ++ G P
Sbjct: 1020 PGLKGHNGLQGLPGIAGHHGDQGAP 1044
Score = 99.0 bits (245), Expect = 4e-20
Identities = 244/1073 (22%), Positives = 328/1073 (30%), Gaps = 182/1073 (16%)
Query: 39 AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG--GGGGGAGSGGGPGA 96
A + E K AG GPP P G++ +DG G G G G GG A
Sbjct: 20 ATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAA 79
Query: 97 EPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAP---PHSAAAALPPPAYGFGQP 153
+ D K GP + PPG G G P P P A G P
Sbjct: 80 QYDGKGVGLGPGPMGLMGPR--GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGP 137
Query: 154 YGRS-----PSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFP 208
G++ P G + PG L G G+ + G G P
Sbjct: 138 PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLP--GFKGIRGHNGLDGLKGQPGAP 195
Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPG-------SGAAAAAGSKPPPSSSASA 259
+ P + P A L RG G PG G+ G P S+
Sbjct: 196 GVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPP 255
Query: 260 SSSSSSFAQQRFGAMGGGGPSAAGG-----------GTPQPTATPTLNQLLTSPSSARGY 308
+ + GA+G GP+ G G P P N L + A+G
Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGL----TGAKGA 311
Query: 309 QGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSG 368
G PG +G P GP + A A A G S G SG
Sbjct: 312 AGLPG--VAGAP----GLPGPRGIPGPVGAAGATGARGLVGEPGPAG-------SKGESG 358
Query: 369 GGGQPLARTPQ-PSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427
G+P + PQ P P + GK P G+ GPP P G G P P
Sbjct: 359 NKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS------AGPPGPP----GLRGSPGSRGLP 408
Query: 428 QRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQ 487
GRA MG P G +GP+ G G+ P P
Sbjct: 409 -----GADGRA-GVMGPPGSRGASGPAGVRGPN--GDAGRPGEPGLMGPRGLPGSPGNIG 460
Query: 488 QPPSQTPHAQPSYQQQPQSQPPQLQSSQP-----PYSQQPSQPPHQQSP----------- 531
+ P P +P P +P P + P+ P +
Sbjct: 461 PAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARG 520
Query: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ-QPAPSTLSQQAAYPQPQSQQSQ-- 588
AP P + Q P Q Q P Q P PS + + P + +
Sbjct: 521 APGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFG 580
Query: 589 ---QTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQED-------MNLSLQSRPSS 638
+R PP + + G S PS G + + + S PS
Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640
Query: 639 LPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPS 698
LP G+ +P G PG+ +GE NP + +P G GP+ +
Sbjct: 641 LPGERGAA-GIPGGKGEKGEPGL--------RGEIGNPGRD--GARGAPGAVGAPGPAGA 689
Query: 699 PVGSPASVAQSRSGPLSPAAVPG--NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRN 756
+ A +GP P PG ++ P P+G + + Q +RG
Sbjct: 690 TGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA--GAAGQPGAKGERGAKGPK 747
Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--------GQYGPQG- 807
+ P A P P+G G S G GP G G+ GP G
Sbjct: 748 GENGVVGPTGPVGAAGPAGPNGPPGPAG-------SRGDGGPPGMTGFPGAAGRTGPPGP 800
Query: 808 ----GYPRQPNYNALPNANYP--------SAGMAGGINPMGAGGQ--------MHGQPGI 847
G P P P G G + P G G+ G PG
Sbjct: 801 SGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGT 860
Query: 848 P-PYGTL-PPGRMS-HASMGNRPYGPNMANMPPQVGS-GMCPPPGGMNRKTQETAVAMHV 903
P P G L PG + S G R P +A + G G+ PPG + ++
Sbjct: 861 PGPQGLLGAPGILGLPGSRGERGL-PGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNG 919
Query: 904 A-------ANSIQNRPP------------GYP-NMNQGGMMGTGPPYG-------QGINS 936
A N + PP GYP N+ G G P+G G
Sbjct: 920 APGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRG 979
Query: 937 MAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP 989
G P GP ++G + G+ G + P K +N G P
Sbjct: 980 ETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLP 1032
Score = 90.5 bits (223), Expect = 2e-17
Identities = 209/858 (24%), Positives = 281/858 (32%), Gaps = 130/858 (15%)
Query: 35 AGGEAAAAAAAERGEM--KAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGG 92
AG A E G K +G + E + GP P G ++G G G AGS G
Sbjct: 336 AGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKR----GPNGEAGSAG 391
Query: 93 GPGAEPDLKNSNGNAG-PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG 151
PG P L+ S G+ G P + PPG G GV P A P G
Sbjct: 392 PPGP-PGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMG-- 448
Query: 152 QPYGR--SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPN 209
P G SP + A + G PG+ G G + P AG + + GFP
Sbjct: 449 -PRGLPGSPGNIGPAG------KEGPVGLPGI----DGRPGPIGP-AGARGEPGNIGFPG 496
Query: 210 HQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQ 269
+ + P ++ A L+ RG G A G PP
Sbjct: 497 PKGPTGDPGKNGDKGHA---GLAGARGAPGPDGNNGAQG---PPGPQGVQGGKGEQGPPG 550
Query: 270 RFGAMGGGGPSAAGGGTPQPTATPTLNQL-LTSPSSARGYQGYPGGDYSGGPQDGGAGKG 328
G G GPS G +P + L P+ RG +G PG + GP +G
Sbjct: 551 PPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRG 610
Query: 329 PA-----DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR----TPQ 379
P+ D G A A + A PG G G+P R P
Sbjct: 611 PSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG 670
Query: 380 PSSPMDQMGKM-RPQPYGGTNPYSQQQGP-PSGPQQGHGYPGQPYGSQTPQRYPMTMQGR 437
G + P P G T + P+GP G PG+ R
Sbjct: 671 RDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGE----------------R 714
Query: 438 AQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496
+ G P G GP+G GQ G + P + P A
Sbjct: 715 GEVGPAG--------PNGFAGPAGAAGQPGAKGERGAKGPKGENGVVG----PTGPVGAA 762
Query: 497 QPSYQQQPQSQPPQLQSSQPP-YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQ 555
P+ P PP + P P P S P P +
Sbjct: 763 GPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGP-----SGISGPPGPPGPAGKEG 817
Query: 556 AQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSA 615
+ P + Q P T A P + + + + PP Q G A
Sbjct: 818 LRGP---RGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLG-----A 869
Query: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS----PG-VSTSGISSS 669
P + G + + L P ++G++ + P+G G PG V + G++ +
Sbjct: 870 PGILGLPGSRGERGL---------PGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGA 920
Query: 670 QGE---QSNPAQS-PFSPHTSPHLPGIRG--PSPSPVGSPASVAQSRSGPLSPAAVPGN- 722
GE NP P P G RG + PVG A+ A GP+ PA GN
Sbjct: 921 PGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG--AAGAPGPHGPVGPAGKHGNR 978
Query: 723 -QMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI 781
+ P P G + ++ RG PQ + +PG PR G +
Sbjct: 979 GETGPSGPVGPAGAV-----------GPRG--PSGPQGIRGDKGEPGEK-GPRGLPGLKG 1024
Query: 782 HTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMG-AG 838
H G+ G +G QG G GP G PR P + P G G + P G G
Sbjct: 1025 HNGLQGLP-GIAGHHGDQGAPGSVGPAG--PRGPAGPSGPAGKDGRTGHPGTVGPAGIRG 1081
Query: 839 GQMHGQPGIPPYGTLPPG 856
Q H P PP PPG
Sbjct: 1082 PQGHQGPAGPPGPPGPPG 1099
Score = 82.0 bits (201), Expect = 5e-15
Identities = 192/789 (24%), Positives = 243/789 (30%), Gaps = 116/789 (14%)
Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66
P +A G PP P E K+ + AG G + G + +GPP
Sbjct: 363 PGSAGPQG-PPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGS-RGLPGADGRAGVMGPP 420
Query: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPG--AEPDLKNSNGNAGPRPALNNNLTEPPGGG 124
G G G G AG G PG L S GN GP E P G
Sbjct: 421 GSRGASGPAGVR----GPNGDAGRPGEPGLMGPRGLPGSPGNIGPAG------KEGPVGL 470
Query: 125 GGGSSDGVGAPPHSAAAALPPPAYGFGQPYG----------RSPSAVAAAAAAVFHQ-QH 173
G DG P A A P GF P G + + +A A A +
Sbjct: 471 PG--IDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNN 528
Query: 174 GGQQSPGLAALQSG-------GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPA 226
G Q PG +Q G G G + GP + + G P + + P
Sbjct: 529 GAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGER-----GLHGEFGLPG 583
Query: 227 PAYALSSPRG--GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283
PA PRG G PG SGAA G S + GA+G GPS
Sbjct: 584 PA----GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPS 639
Query: 284 G--GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341
G G P P RG G PG D + G GPA A A
Sbjct: 640 GLPGERGAAGIPGGKGEKGEP-GLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGA 698
Query: 342 AAAAAAAASGGAQ-QRSHHAPMSP----GSSGGGGQPLARTPQ-PSSPMDQMGKMRPQ-P 394
A A A G+ +R P P G +G GQP A+ + P + G + P P
Sbjct: 699 AGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGP 758
Query: 395 YGGTNPYSQQQGPP--------SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLS 446
G P + GPP GP G+PG +T P + G G
Sbjct: 759 VGAAGP-AGPNGPPGPAGSRGDGGPPGMTGFPGA--AGRTGPPGPSGISG-PPGPPGPAG 814
Query: 447 YTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502
P G QGP G G G + ++ P + P Q P
Sbjct: 815 KEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILG 874
Query: 503 QPQS--------------QPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQ 548
P S +P L + PP ++ P P +
Sbjct: 875 LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDG 934
Query: 549 PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608
PP Q ++ P P A P P + + P
Sbjct: 935 PPGRDGQPGHKGERGYPGNIGP---VGAAGAPGPHGPVGPAGKHGNRGETGPSG-PVGPA 990
Query: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS 668
G+ PS +G + D + P LP L G G +G GI+
Sbjct: 991 GAVGPRGPS--GPQGIRGDKGEPGEKGPRGLPGLKGH-----NGLQG-------LPGIAG 1036
Query: 669 SQGEQSNPAQ-SPFSPHTSPHLPGIRGPS-----PSPVGSPASV--AQSRSGPLSPAAVP 720
G+Q P P P G G P VG PA + Q GP P P
Sbjct: 1037 HHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVG-PAGIRGPQGHQGPAGPPGPP 1095
Query: 721 GNQMPPRPP 729
G PP PP
Sbjct: 1096 G---PPGPP 1101
Score = 69.7 bits (169), Expect = 3e-11
Identities = 131/511 (25%), Positives = 173/511 (33%), Gaps = 105/511 (20%)
Query: 3 AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA 62
A+ AP A + P P + + E AG + ERGE+ A GPA
Sbjct: 674 ARGAPGAVGA----PGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA 729
Query: 63 VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG 122
QP G + + GA+ G G G G GA G AGP N P G
Sbjct: 730 GAAGQP-GAKGERGAK-GPKGENGVVGPTGPVGAA-------GPAGP-----NGPPGPAG 775
Query: 123 GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLA 182
G G G+ P +A PP G P P A G Q G
Sbjct: 776 SRGDGGPPGMTGFPGAAGRTGPPGPSGISGP----PGPPGPAGKEGLRGPRGDQGPVG-- 829
Query: 183 ALQSGGGGGLEP--YAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240
++G G + P +AG + S + G +A PP GTPG
Sbjct: 830 --RTGEVGAVGPPGFAGEKGPSGEAG-------------TAGPP------------GTPG 862
Query: 241 -SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLL 299
G A G P S + A G +G GP A G P +P +N
Sbjct: 863 PQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGA-RGPPGAVGSPGVN--- 918
Query: 300 TSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH 359
+P A G G PG D GP G P + + AA A G H
Sbjct: 919 GAPGEA-GRDGNPGND---GPP--GRDGQPGHKGERGYPGNIGPVGAAGAPG------PH 966
Query: 360 APMSP-GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYP 418
P+ P G G G+ PS P+ G + P+ PSGPQ G
Sbjct: 967 GPVGPAGKHGNRGE-----TGPSGPVGPAGAVGPR-------------GPSGPQGIRGDK 1008
Query: 419 GQPYGSQTPQRYPMTMQGRAQSAMGGLS-------YTQQIPPYGQQGPSG----YGQQGQ 467
G+P G + P+ P + G++ + P G +GP+G G+ G+
Sbjct: 1009 GEP-GEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067
Query: 468 TPYYNQQSP----HPQQQQPPYSQQPPSQTP 494
T + P PQ Q P P P
Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP 1098
Score = 55.8 bits (133), Expect = 4e-07
Identities = 94/390 (24%), Positives = 118/390 (30%), Gaps = 95/390 (24%)
Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGP 61
A + P S + PP PP AG E ++G + G+ E
Sbjct: 792 AGRTGPPGPSGISGPPGPP------------GPAGKEGLRGPRGDQGPV----GRTGEVG 835
Query: 62 AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121
AVGPP G++ G G AG+ G P G GP+ L
Sbjct: 836 AVGPPGFAGEK----------GPSGEAGTAGPP----------GTPGPQGLL-------- 867
Query: 122 GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL 181
G+ +G P LP A G+P P +A G + PG
Sbjct: 868 -----GAPGILGLPGSRGERGLPGVAGAVGEP---GPLGIAGPP--------GARGPPG- 910
Query: 182 AALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYP---PPAPAYALSSPRGGT 238
A+ S G G AG N + G P + YP P A P G
Sbjct: 911 -AVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPV 969
Query: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--------GTPQPT 290
+G G P A GA+G GPS G G P
Sbjct: 970 GPAGKHGNRGETGPSGPVGPA------------GAVGPRGPSGPQGIRGDKGEPGEKGPR 1017
Query: 291 ATPTLN-----QLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345
P L Q L + G QG PG GP+ GPA + A
Sbjct: 1018 GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPA 1077
Query: 346 AAAASGGAQQRS-----HHAPMSPGSSGGG 370
G Q + P PG SGGG
Sbjct: 1078 GIRGPQGHQGPAGPPGPPGPPGPPGVSGGG 1107
Score = 33.9 bits (76), Expect = 1.7
Identities = 80/352 (22%), Positives = 105/352 (29%), Gaps = 71/352 (20%)
Query: 1109 RGEDPPPDI--FAAADSKKSQPKIQ-------PPSPAGSGSMQGPQTPQSTSSSMAEGGD 1159
RG+ PP + F A + P PP PAG ++GP+ Q E G
Sbjct: 777 RGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836
Query: 1160 LKPP---------------TPASTPHSQ-------IPPLPGMSRSNSV-GIQDAFNDGSD 1196
+ PP P TP Q I LPG + G+ A +
Sbjct: 837 VGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGP 896
Query: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM 1256
PG S + G + N PG+D GP G
Sbjct: 897 LGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGN----------PGND-------GPPGRD 939
Query: 1257 GDPYSRAAGPGLGNV-----AMGPRQHYPYG--GPY-DRVRTEPG--IGPEGNMSTGAPQ 1306
G P + GN+ A P H P G G + +R T P +GP G + P
Sbjct: 940 GQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPS 999
Query: 1307 --PNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQ 1364
+ + G P P + Q QG P GS P+
Sbjct: 1000 GPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAP-GSVGPAGPRGPAGP 1058
Query: 1365 QQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1416
P + + P H G AGPP P P P PP
Sbjct: 1059 SGPAGKDGRTGHPGTVGPAGIRGPQGHQG----PAGPPGP-----PGPPGPP 1101
Score = 31.6 bits (70), Expect = 8.4
Identities = 46/178 (25%), Positives = 59/178 (33%), Gaps = 16/178 (8%)
Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFN 1192
P P G+ QGP PQ E G PP P P + + G+ F
Sbjct: 522 PGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLP-GPSGPAGEVGKPGERGLHGEF- 579
Query: 1193 DGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252
G R P PG + + +G P G+ + PG + + GP
Sbjct: 580 -GLPGPAGPRGERGP-PGESGAAGPTGPIGSRGPSGPPGPDGN-KGEPGVVGAVGTA-GP 635
Query: 1253 NGGMGDPYSRAAG--PGLGNVAMGPRQHYPYGGP-YDRVRTEPGIGPEGNMSTGAPQP 1307
+G G P R A PG P G P D R PG + GAP P
Sbjct: 636 SGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPG-------AVGAPGP 686
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 100 bits (249), Expect = 1e-20
Identities = 172/702 (24%), Positives = 231/702 (32%), Gaps = 102/702 (14%)
Query: 102 NSNGNAGPRPA-LNNNLTEP----PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGR 156
N +G++ PR +N T P PG S G A PPP + P +
Sbjct: 114 NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF---PPSPQ 170
Query: 157 SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYY 216
P + A F P + +G +EP + P H Y
Sbjct: 171 PPDSTPRQPEASFE--------PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP--QLY 220
Query: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK------PPPSSSASASSSSSSFAQQR 270
P + LS P G G GAA++ G PPP++ S SSS +S
Sbjct: 221 PGGTGG-------VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGAS----- 268
Query: 271 FGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPA 330
GA P+ GG P+A P N +P+ P + S P GA P
Sbjct: 269 -GAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG 327
Query: 331 DMAS-QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGK 389
+ S G G S H+ + P SS P+ R P SS
Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS-LPPASSSAPAPPM-RFPYSSSSSSSAAA 385
Query: 390 MRPQPYGGTN--PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSY 447
++ P+ Q PS P H +P P + P Q S
Sbjct: 386 SSSSSSSSSSASPFPASQALPSYP---HSFP-PPTSLSVSNQPPKYTQPSLPSQAVWSQG 441
Query: 448 TQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQ 507
PPYG+ + G P P + PP T H QQQ Q Q
Sbjct: 442 PPPPPPYGRLLANSNAHPG---------PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQ 492
Query: 508 PPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP-YQQQQPQ 566
Q Q Q + PP P +P H ++ P A SP +P
Sbjct: 493 QQQQQQQQQQHHGNSGPPP----PGAFPHPLEGGSSH------HAHPYAMSPSLGSLRPY 542
Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQ--QRFPPPQELSQDSFGSQASSAP-SMTSSKG 623
P P+ L P P SQ S YSQ PP S S + S P S S
Sbjct: 543 PPGPAHL------PPPHSQVS----YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592
Query: 624 GQEDMNLSLQSRP------SSLPDLSGSIDDLPMGTEGALSPGVSTSG-ISSSQGEQSNP 676
G + P ++L + ++ P G + A PG G + S G
Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTA 652
Query: 677 AQSPFSPHTSPHL-----PGIRGPSPSPVG----SPASVAQSRSGPLSPAAVPGNQMPPR 727
+ P + P PG RG SP P G P S GPL PA G P
Sbjct: 653 TPPGYKPGSPPSFRTGTPPGYRGTSP-PAGPGTFKPGSPTVG-PGPLPPAGPSGLPSLPP 710
Query: 728 PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ--MPQYSSPQP 767
PP+ + P ++ + I Q+ P+ +P SP P
Sbjct: 711 PPAAPASG---PPLSATQIKQEPAEEYETPESPVPPARSPSP 749
Score = 97.4 bits (241), Expect = 1e-19
Identities = 199/825 (24%), Positives = 263/825 (31%), Gaps = 151/825 (18%)
Query: 225 PAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284
P P L S +PG + +++ K S + + + + G +
Sbjct: 21 PGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESE 80
Query: 285 G--TPQPTATPTLNQLLT--SPSSARGYQGYP-GGDYSGGPQDGGAGKGPADMASQCWGA 339
T P T T +L SPS G D S P+D + G+
Sbjct: 81 SEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGS 140
Query: 340 AAAAA-AAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTP-QPSSPMDQMGKMRPQPYGG 397
+ +++ S G + H P+ P S QP TP QP + + + P Y
Sbjct: 141 VENDSDSSSGLSQGPARPYHPPPLFPPSP----QPPDSTPRQPEASFEPHPSVTPTGYHA 196
Query: 398 TN--PYSQQ-QGPPSGPQ-QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453
P S+ Q PP P YPG G + G A S G Q PP
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513
S G G P +P P S PP+ PH P+ P +P S
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLP--SAPPPANFPHVTPNLPPPPALRPLNNAS 314
Query: 514 SQPPYSQQPSQPPHQQSP----------APYPSQQSTTQQHPQSQPPYSQ----PQAQSP 559
+ PP P H SP P P + T P S PP S P + P
Sbjct: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374
Query: 560 YQQQQPQQPAPSTLSQQA---AYPQPQSQQSQQTAYSQQRFPPPQELS---------QDS 607
Y A S+ S + A P P SQ +S FPPP LS Q S
Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS---FPPPTSLSVSNQPPKYTQPS 431
Query: 608 FGSQA--SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSG 665
SQA S P G + + + P P +G+ + P VST
Sbjct: 432 LPSQAVWSQGPPPPPPYGR---LLANSNAHPGPFPPSTGA--------QSTAHPPVSTHH 480
Query: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMP 725
Q +Q Q H SGP P A P
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQH-------------------HGNSGPPPPGAFP----- 516
Query: 726 PRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQ--PSGGQIHT 783
P G S HP S+ R Y P P + P P S +S Q P+G + +
Sbjct: 517 -HPLEGGSSHHAHPYAMSPSLGSLRPY----PPGPAHLPP-PHSQVSYSQAGPNGPPVSS 570
Query: 784 GMGSYQQNSMGSYG---PQGGQYGPQGG-YPRQPNYNALPNANYPSAGMAGGINPMG--- 836
S S GSY P Q GPQG YP P +P SA ++ I +
Sbjct: 571 SSNSSSSTSQGSYPCSHPSPSQ-GPQGAPYPFPP----VPTVTTSSATLSTVIATVASSP 625
Query: 837 AGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQE 896
AG + PG PPYG P ++ + Y P PP +G
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---PPSFRTGT------------- 669
Query: 897 TAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMA------GMINPQGPPYSM 950
PPGY GT PP G G G + P GP S
Sbjct: 670 ---------------PPGY--------RGTSPPAGPGTFKPGSPTVGPGPLPPAGP--SG 704
Query: 951 GGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKS 995
++ A A+ P + +K PA + P S S
Sbjct: 705 LPSLPPPPAAPASGPPLSAT-QIKQEPAEEYETPESPVPPARSPS 748
Score = 67.8 bits (164), Expect = 1e-10
Identities = 150/640 (23%), Positives = 198/640 (30%), Gaps = 143/640 (22%)
Query: 17 PPP--PPSELKKAEQQQREEAGGEA--AAAAAAERGEMKAAAGQESEGPAVGPPQ----- 67
PPP PPS ++ EA E + M+ + + P PP
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220
Query: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGA--------EPDLKNSNGNAGPRPALNNNLTE 119
P G G GGG A S GGP P +S+G +G P T
Sbjct: 221 PGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT--KPPTT 278
Query: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP 179
P GGG S+ PH PPPA SP + A Q G
Sbjct: 279 PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA-------QPLPGHLPS 331
Query: 180 GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTP 239
A Q GG P GP H P P S+ P P + SS
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLP--------PASSSAPAPPMRFPYSS------ 377
Query: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLL 299
S +++AA S SSS+SAS +S A + S + P P+L
Sbjct: 378 -SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL---- 432
Query: 300 TSPSSARGYQGYPGGD-YSGGPQDGGAGKGPADMASQCWGAAAAAAAA------------ 346
PS A QG P Y + A GP ++ A +
Sbjct: 433 --PSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ 490
Query: 347 -AAASGGAQQRSHHAPMSPGSSGGGGQPL----ARTPQPSSPMDQMGKMRPQPYGGTN-- 399
QQ+ HH P G PL + P + +G +RP P G +
Sbjct: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP 550
Query: 400 -PYSQ---QQGPPSGP------------QQGHGYPGQPYGSQTPQRYPM----------- 432
P+SQ Q P+GP QG P SQ PQ P
Sbjct: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610
Query: 433 -----TMQGRAQSAMGGLSYTQQI--PPYGQQGPS----------GYG-------QQGQT 468
T+ S+ G PPYG++ PS GY + G
Sbjct: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
Query: 469 PYYNQQSPHPQQ------------------------QQPPYSQQPPSQTPHAQPSYQQQP 504
P Y SP PP P S P + +Q+P
Sbjct: 671 PGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP 730
Query: 505 QSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQH 544
+ +S PP ++ PS PP + SQ + +H
Sbjct: 731 AEEYETPESPVPP-ARSPSPPPKVVDVPSHASQSARFNKH 769
Score = 58.5 bits (140), Expect = 6e-08
Identities = 186/869 (21%), Positives = 278/869 (31%), Gaps = 143/869 (16%)
Query: 654 EGALSPGVSTSG----ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS 709
E A +P V+ G IS S+ E++N +P T LP R SPS + S + +
Sbjct: 60 EEASTPKVNKQGRSEEISESESEETN---APKKTKTEQELP--RPQSPSDLDSLDGRSLN 114
Query: 710 RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD--RGY-----MQRNPQMPQY 762
G P + + P S+ + S + S ++Q R Y +PQ P
Sbjct: 115 DDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDS 174
Query: 763 SSPQPGSALSPRQ---PSG--GQIHTGMGSYQQNSMGSYGPQ-----GGQYGPQGGYPRQ 812
+ QP ++ P P+G + Q G+ P GG G G P
Sbjct: 175 TPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG 234
Query: 813 PNYNALPNANYPSAGMAGGINPMGAGGQMHGQP------------GIPPYGTLPPGRMSH 860
P +A GG N GG+ H P G PP T PP +
Sbjct: 235 PKGGG-------AASSVGGPN----GGKQHPPPTTPISVSSSGASGAPP--TKPP--TTP 279
Query: 861 ASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQ 920
GN P P AN P + PPP + +A + A + P M Q
Sbjct: 280 VGGGNLPSAPPPANFPHVTPN--LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQ 337
Query: 921 G-GMMGTGPPYGQGINSMAGMINPQG-----PPYSMGGTMANNSAGMAASPEMMGLGDVK 974
G G + GP G + + P PP + +++S+ A+S
Sbjct: 338 GMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397
Query: 975 LTPATK-MNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEE 1033
PA++ + + P S S + T + P R LA +
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457
Query: 1034 KAMGM---TNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090
T + P+ + + ++ Q + ++ ++ + G S
Sbjct: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQ-----QQQQQQQQQQQQQQQHHGNSGPPPP 512
Query: 1091 SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAG--------SGSMQ 1142
AF +E G +A + S S + PP PA S S
Sbjct: 513 G----------AFPHPLEGGSSHHAHPYAMSPSLGSL-RPYPPGPAHLPPPHSQVSYSQA 561
Query: 1143 GPQTPQSTSSSMAEGGDLKPPTPASTPHSQ---------IPPLPGMSRSNSVGIQDAFND 1193
GP P +SSS + + P S P PP+P ++ S++
Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATV 621
Query: 1194 GSDSTFQKRNSMTPNPGY---QPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQ 1250
S K S P Y PS Y+P P PG G
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPG-----YRGT 676
Query: 1251 GPNGGMG--DPYSRAAGPG-------LGNVAMGPRQHYPYGGP---YDRVRTEPGIGPEG 1298
P G G P S GPG G ++ P P GP +++ EP E
Sbjct: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP--AEEY 734
Query: 1299 NMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG-----TPSGSP 1353
P PS P + PS Q + +H G + GS
Sbjct: 735 ETPESPVPPARSPSPPPKVVDVPSH---ASQSARFNKHLDRGFNSCARSDLYFVPLEGSK 791
Query: 1354 FPSQQTTMY-------QQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAG-PPVPA 1405
++ + +Q+ + R E K L +K+ + G PV
Sbjct: 792 LAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVEC 851
Query: 1406 SHIAPAPVQPPMIRRDITFPPGSVEATQP 1434
+ P P +PP F PGS AT P
Sbjct: 852 PSLGPVPHRPP-------FEPGSAVATVP 873
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 110,990,868
Number of Sequences: 37866
Number of extensions: 7584739
Number of successful extensions: 110823
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 758
Number of HSP's successfully gapped in prelim test: 2790
Number of HSP's that attempted gapping in prelim test: 38885
Number of HSP's gapped (non-prelim): 40516
length of query: 2068
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1950
effective length of database: 13,779,330
effective search space: 26869693500
effective search space used: 26869693500
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.