BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] (2285 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 4707 0.0 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 2841 0.0 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 1998 0.0 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 1992 0.0 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 1974 0.0 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 123 2e-27 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 119 3e-26 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 117 2e-25 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 112 3e-24 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 112 5e-24 gi|57864582 hornerin [Homo sapiens] 107 1e-22 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 107 2e-22 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 106 3e-22 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 106 3e-22 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 105 7e-22 gi|153792074 proline rich 12 [Homo sapiens] 105 7e-22 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 103 1e-21 gi|55956910 meningioma 1 [Homo sapiens] 103 3e-21 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 103 3e-21 gi|150170670 piccolo isoform 2 [Homo sapiens] 102 3e-21 gi|150378539 piccolo isoform 1 [Homo sapiens] 102 3e-21 gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 102 4e-21 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 102 6e-21 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 102 6e-21 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 102 6e-21 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 101 1e-20 gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 101 1e-20 gi|163965366 nascent polypeptide-associated complex alpha subuni... 100 1e-20 gi|48762934 alpha 2 type I collagen [Homo sapiens] 100 2e-20 gi|55750053 atrophin-1 [Homo sapiens] 100 2e-20 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 4707 bits (12209), Expect = 0.0 Identities = 2285/2285 (100%), Positives = 2285/2285 (100%) Query: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG Sbjct: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60 Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP Sbjct: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120 Query: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG Sbjct: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 Query: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA Sbjct: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360 Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ Sbjct: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420 Query: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ Sbjct: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480 Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST Sbjct: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540 Query: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600 Query: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG Sbjct: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660 Query: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720 Query: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ Sbjct: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780 Query: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ Sbjct: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840 Query: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA Sbjct: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900 Query: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG Sbjct: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960 Query: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER Sbjct: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020 Query: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL Sbjct: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080 Query: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS Sbjct: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140 Query: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ Sbjct: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200 Query: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY Sbjct: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260 Query: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS Sbjct: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320 Query: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPP 1380 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPP Sbjct: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPP 1380 Query: 1381 AKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATAT 1440 AKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATAT Sbjct: 1381 AKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATAT 1440 Query: 1441 AATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQG 1500 AATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQG Sbjct: 1441 AATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQG 1500 Query: 1501 RNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAP 1560 RNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAP Sbjct: 1501 RNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAP 1560 Query: 1561 VPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1620 VPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV Sbjct: 1561 VPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1620 Query: 1621 PASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGL 1680 PASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGL Sbjct: 1621 PASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGL 1680 Query: 1681 LAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPG 1740 LAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPG Sbjct: 1681 LAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPG 1740 Query: 1741 QRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASEN 1800 QRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASEN Sbjct: 1741 QRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASEN 1800 Query: 1801 SEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFE 1860 SEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFE Sbjct: 1801 SEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFE 1860 Query: 1861 SKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSS 1920 SKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSS Sbjct: 1861 SKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSS 1920 Query: 1921 TLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKR 1980 TLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKR Sbjct: 1921 TLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKR 1980 Query: 1981 CVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQG 2040 CVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQG Sbjct: 1981 CVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQG 2040 Query: 2041 VSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQ 2100 VSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQ Sbjct: 2041 VSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQ 2100 Query: 2101 DPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKN 2160 DPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKN Sbjct: 2101 DPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKN 2160 Query: 2161 PVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQN 2220 PVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQN Sbjct: 2161 PVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQN 2220 Query: 2221 PPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLF 2280 PPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLF Sbjct: 2221 PPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLF 2280 Query: 2281 LIGQS 2285 LIGQS Sbjct: 2281 LIGQS 2285 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 2841 bits (7365), Expect = 0.0 Identities = 1385/1449 (95%), Positives = 1393/1449 (96%), Gaps = 21/1449 (1%) Query: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG Sbjct: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60 Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP Sbjct: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120 Query: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG Sbjct: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 Query: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA Sbjct: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360 Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ Sbjct: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420 Query: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ Sbjct: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480 Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST Sbjct: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540 Query: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP Sbjct: 541 TQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP 600 Query: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG Sbjct: 601 QELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660 Query: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720 Query: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ Sbjct: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780 Query: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ Sbjct: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQ 840 Query: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA Sbjct: 841 MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVA 900 Query: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG Sbjct: 901 MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAG 960 Query: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER Sbjct: 961 MAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPER 1020 Query: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL Sbjct: 1021 KMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNL 1080 Query: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS Sbjct: 1081 NVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGS 1140 Query: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ Sbjct: 1141 MQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200 Query: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY Sbjct: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPY 1260 Query: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS Sbjct: 1261 SRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYS 1320 Query: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQ-----NYKRPMDG 1375 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQ RPM+ Sbjct: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMEN 1380 Query: 1376 TYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAY 1435 P P+ G Q+ PP PAS P+P Q + + Sbjct: 1381 RTSPSKS---------PF-LHSGMKMQKAGPPV---PASH---IAPAPVQPPMIRRDITF 1424 Query: 1436 PATATAATE 1444 P + AT+ Sbjct: 1425 PPGSVEATQ 1433 Score = 1420 bits (3676), Expect = 0.0 Identities = 753/946 (79%), Positives = 773/946 (81%), Gaps = 48/946 (5%) Query: 1379 PPAKRHEGEMYS--VPYSTGQGQPQQQQLPPAQPQPASQQQAAQP-------SPQQDVYN 1429 PP+ G M P ST + L P P PAS + P S + + Sbjct: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKP--PTPASTPHSQIPPLPGMSRSNSVGIQD 1189 Query: 1430 QYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASA 1489 + + +T P G Q R+S P + +M P +S Sbjct: 1190 AFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSG 1249 Query: 1490 EVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYH-GVNRTDEMLHTDQRANHEGSWPSH 1548 + G Y+ A G+ GP H + + T+ EG+ S Sbjct: 1250 QGPNGGM------GDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNM-ST 1302 Query: 1549 GTRQPPYGPSAPVPPMTRP---PPSNYQ----------------------PPPSMQNHI- 1582 G QP PS P M P PP Q P PS Q + Sbjct: 1303 GAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMY 1362 Query: 1583 ---PQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDI 1639 QVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDI Sbjct: 1363 QQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDI 1422 Query: 1640 TFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDN 1699 TFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDN Sbjct: 1423 TFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDN 1482 Query: 1700 SIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPM 1759 SIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPM Sbjct: 1483 SIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPM 1542 Query: 1760 EGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQK 1819 EGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQK Sbjct: 1543 EGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQK 1602 Query: 1820 NDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPR 1879 NDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPR Sbjct: 1603 NDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPR 1662 Query: 1880 KHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKF 1939 KHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKF Sbjct: 1663 KHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKF 1722 Query: 1940 PFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDF 1999 PFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDF Sbjct: 1723 PFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDF 1782 Query: 2000 EMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLREN 2059 EMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLREN Sbjct: 1783 EMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLREN 1842 Query: 2060 TLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVL 2119 TLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVL Sbjct: 1843 TLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVL 1902 Query: 2120 ETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS 2179 ETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS Sbjct: 1903 ETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS 1962 Query: 2180 LAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALL 2239 LAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALL Sbjct: 1963 LAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALL 2022 Query: 2240 ALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS 2285 ALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS Sbjct: 2023 ALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS 2068 Score = 86.3 bits (212), Expect = 3e-16 Identities = 141/573 (24%), Positives = 200/573 (34%), Gaps = 73/573 (12%) Query: 1102 AFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLK 1161 A+ RG P AAA SK PPS + S S Q +M GG Sbjct: 228 AYALSSPRGGTPGSGAAAAAGSKP------PPSSSASASSSSSSFAQQRFGAMGGGGPSA 281 Query: 1162 P----PTPASTPH-SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMN 1216 P P +TP +Q+ P +R G Q G D + ++ G P+ Sbjct: 282 AGGGTPQPTATPTLNQLLTSPSSAR----GYQGY--PGGDYSGGPQDG---GAGKGPADM 332 Query: 1217 TSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPR 1276 S G + + MS G +GG G P +R P MG Sbjct: 333 ASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS--SGGGGQPLARTPQPSSPMDQMGKM 390 Query: 1277 QHYPYGG--PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334 + PYGG PY + + P +G+ G P G +P RYP Q + Q Sbjct: 391 RPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPY----------GSQTPQRYPMTMQGRAQS 440 Query: 1335 RHD--SYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVP 1392 SY Q G S + Q T Y QQ + + Y P Sbjct: 441 AMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQP----------P 490 Query: 1393 YSTGQGQPQQQQLPPAQP------QPASQQQAAQPSPQQDVYNQYGNAYPATATAATERR 1446 T QP QQ P +QP QP QQ +QP P Q Y + T + Sbjct: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP-PHQQSPAPYPSQQSTTQQHPQSQP 549 Query: 1447 PAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTY 1506 P PQ Q P+Q + + A P T +QQ PQ Q S + A + +++ Sbjct: 550 PYSQPQAQSPYQQQQPQQPA-PSTLSQQAAYPQPQS---QQSQQTAYSQQRFPPPQELSQ 605 Query: 1507 NYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANH----EGS-----WPSHGTRQP---P 1554 + Q++ SAP + G + D L R + GS + G P Sbjct: 606 DSFGSQAS-SAPSMTSSKG-GQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST 663 Query: 1555 YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQ 1614 G S+ + P S + P S H+P + P+P P + S+S L Sbjct: 664 SGISSSQGEQSNPAQSPFSPHTS--PHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPG 721 Query: 1615 KAGPPVPASHIAPAPVQPPMIRRDITFPPGSVE 1647 PP P S + + + P M + I G ++ Sbjct: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQ 754 Score = 73.2 bits (178), Expect = 3e-12 Identities = 205/995 (20%), Positives = 307/995 (30%), Gaps = 175/995 (17%) Query: 714 LSPAAVPG-NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS 772 ++PAA PP PPS + A +R G A+ Sbjct: 5 VAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVG 64 Query: 773 PRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGI 832 P QP G ++ G S + G GG G GG +P+ L N+N +AG + Sbjct: 65 PPQPLGKELQDGAES-------NGGGGGGGAGSGGGPGAEPD---LKNSN-GNAGPRPAL 113 Query: 833 N------PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPP 886 N P G GG G PP H++ P PP G G Sbjct: 114 NNNLTEPPGGGGGGSSDGVGAPP----------HSAAAALP--------PPAYGFGQ--- 152 Query: 887 PGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQG- 945 P G + A A + PG + GG G P G NS + G Sbjct: 153 PYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNS-----HDHGF 207 Query: 946 PPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTN 1005 P + N SA +P TP + A P S + SSSS++ Sbjct: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267 Query: 1006 EKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLT 1065 ++ GG + A + + A G Y+ Y GG Sbjct: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG------YQGYPGGDYSGGPQ 321 Query: 1066 QVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKK 1125 K ++A+ +++AA++ Q +R P + + Sbjct: 322 DGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ---------QRSHHAP--MSPGSSGGG 370 Query: 1126 SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPH--------SQIP--- 1174 QP + P P+ G PQ + PP+ H SQ P Sbjct: 371 GQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY 430 Query: 1175 PLPGMSRSNSV-------------GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221 P+ R+ S G Q G N +P+P Q + Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490 Query: 1222 GRMSYEPNKDPYGSMRKAPGSDP-FMSSGQGPNGGMGD--PYSRAAGP---GLGNVAMGP 1275 S P+ P S ++ P S P + S Q P P+ ++ P P Sbjct: 491 ---SQTPHAQP--SYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545 Query: 1276 RQHYPYG-----GPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQ 1330 + PY PY + + + + PQP S + YS R+PP Q+ Sbjct: 546 QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA--YSQQRFPPPQEL 603 Query: 1331 QQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYS 1390 Q DS+G+Q S+ + + S + + Q + + + G+ EG + Sbjct: 604 SQ----DSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSP 659 Query: 1391 VPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGG 1450 ++G Q +Q PAQ + P + + G+ + + PA Sbjct: 660 GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAV 719 Query: 1451 PQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYAN 1510 P NQ P PP + M P M Q ++ Q R M N Sbjct: 720 PGNQMP--------PRPPSGQSDSIMHPSM------------NQSSIAQDRGYMQRNPQM 759 Query: 1511 RQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVP-------- 1562 Q + P G A + +HT + + S S+G + YGP P Sbjct: 760 PQYSSPQP-GSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNAL 818 Query: 1563 ---------------PMTRP---------PPSNYQPP--------------PSMQNHIPQ 1584 PM PP PP P+M N PQ Sbjct: 819 PNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ 878 Query: 1585 VSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPP 1619 V S P NR + + +H + PP Sbjct: 879 VGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913 Score = 43.1 bits (100), Expect = 0.003 Identities = 74/319 (23%), Positives = 100/319 (31%), Gaps = 47/319 (14%) Query: 1344 STQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQ 1403 S+ G P P PS+ QQQ++ G A GEM + +G Sbjct: 11 SSLGNPPPPP-PSELKKAEQQQREE----AGGEAAAAAAAERGEMKAAAGQESEGPA--- 62 Query: 1404 QLPPAQPQPASQQQAAQ---------------PSPQQDVYNQYGNAYPATATAATERRPA 1448 + P QP Q A+ P + D+ N GNA P A P Sbjct: 63 -VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121 Query: 1449 GGPQNQFPFQFGRDRVSAPPGTNAQQNMPP-----QMMGGPIQASAEVAQQGTMWQGRND 1503 GG D V APP + A PP Q G A A A Q Sbjct: 122 GGGGGG-----SSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQ 176 Query: 1504 MTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPP 1563 + A QS G P Y G Q+ +H+ +P+H + Y P+ P Sbjct: 177 QSPGLAALQSGGGGGLEP-YAG----------PQQNSHDHGFPNH--QYNSYYPNRSAYP 223 Query: 1564 MTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPAS 1623 P + P ++ + P S S S F G P A Sbjct: 224 PPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283 Query: 1624 HIAPAPVQPPMIRRDITFP 1642 P P P + + +T P Sbjct: 284 GGTPQPTATPTLNQLLTSP 302 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 1998 bits (5177), Expect = 0.0 Identities = 1167/2315 (50%), Positives = 1403/2315 (60%), Gaps = 250/2315 (10%) Query: 25 KKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-KELQDGAESNGGG 83 ++ +QQQ+++ + + A G GP + PQ G K+ G +++ G Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Query: 84 GGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSA 139 + G A P + G P L T+ P GGGGG Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP----------- 166 Query: 140 AAALPP--PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG--GLEPY 195 AA+P YG P P A QHGGQQSPG+ + S G Sbjct: 167 -AAVPEFNNYYGSAAPASGGPGGRAGPC----FDQHGGQQSPGMGMMHSASAAAAGAPGS 221 Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255 P QNSH+ G+PN Q N Y P Y+ GG G G Sbjct: 222 MDPLQNSHE-GYPNSQCNHY-----------PGYSRPGAGGGGGGGGGGGGGSG------ 263 Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315 G GGGG A G G A GY G G Sbjct: 264 ----------------GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 Query: 316 ---YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372 S Q GG GP GAA+ + AAA ++ G QR P + Sbjct: 308 GVLSSPRQQGGGMMMGPGG-----GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362 Query: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNP-YSQQQGPP---SGPQQGHGYPGQPYGSQTPQ 428 L +P P + YGG+ P YS PP S PQ G G Q Sbjct: 363 QLLTSPSPMM----------RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ--- 409 Query: 429 RYPMTMQGRAQSAMG---GLSYTQQIPPYGQQGPSGY-----GQQGQTPYYNQQSPHPQQ 480 Q A +G G Y P + + G G T +Q SP Sbjct: 410 ------QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463 Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ-----PSQPPHQQSPAPYP 535 PH+QP QS P S PP Q+ + P + YP Sbjct: 464 VMKRPQLYGMGSNPHSQPQ-----QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518 Query: 536 SQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQ 595 QQ Q Q Y Q Q Q PY QQPQ P L QA Y QSQQ Sbjct: 519 QQQMPPQYGQQGVSGYCQ-QGQQPYYSQQPQPPH---LPPQAQYLPSQSQQ--------- 565 Query: 596 RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEG 655 R+ P Q++SQ+ +G++ S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE Sbjct: 566 RYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEA 623 Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPL 714 LS VS SG +SSQG+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+ Sbjct: 624 TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPI 683 Query: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSAL 771 SPA++PG+QMPP+PP QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++ Sbjct: 684 SPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743 Query: 772 SPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAG 830 SP GGQ+H G+ S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803 Query: 831 GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGM 883 GI+ A QMHGQ P G +P GRM A M NRP+ NM++M P Q G GM Sbjct: 804 GIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860 Query: 884 CPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMIN 942 PP +NRK QE A A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N Sbjct: 861 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMN 920 Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSST 1002 Q PPYSM M N+SA +MM G+ KL K + K +GTP+ ESKSKKSSSST Sbjct: 921 TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 980 Query: 1003 TTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIG 1062 TT EKITK+YELG EPERK+WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIG Sbjct: 981 TTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIG 1040 Query: 1063 GLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAAD 1122 GL QVNKNKKWRELATNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D Sbjct: 1041 GLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD 1100 Query: 1123 SKKSQPKIQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMS 1180 +KK QPK+QPPSPA SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G Sbjct: 1101 TKK-QPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-G 1158 Query: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAP 1240 RS+++ + D F+D SDS+F KRNSMTPN YQ M+ D+MGRM YEPNK Sbjct: 1159 RSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK---------- 1208 Query: 1241 GSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNM 1300 DPF + P G +P+ + G + Y++ P G M Sbjct: 1209 --DPFGGMRKVP--GSSEPF----------MTQGQMPNSSMQDMYNQ-------SPSGAM 1247 Query: 1301 STGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSP-FPSQQT 1359 S + GM ++P +RH+ YG Q+ QG PSG P + Q Sbjct: 1248 S-------------NLGMGQRQQFP--YGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1292 Query: 1360 TMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAA 1419 +Y QQ NYKR MDG YGPPAKRHEG+MY++ YS Sbjct: 1293 GLYPQQP-NYKRHMDGMYGPPAKRHEGDMYNMQYS------------------------- 1326 Query: 1420 QPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQ 1479 S QQ++YNQYG +Y + +RRP Q Q+P+ + R+R+ P G +PPQ Sbjct: 1327 --SQQQEMYNQYGGSY-----SGPDRRPI---QGQYPYPYSRERMQGP-GQIQTHGIPPQ 1375 Query: 1480 MMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRA 1539 MMGGP+Q+S+ Q MW RNDM Y Y NRQ G Q P Y G+NRTD+M+ DQR Sbjct: 1376 MMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRI 1435 Query: 1540 NHEGSWPSHGTRQPPY-GPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENR 1598 NHE WPSH +++ PY SA + P+TRPP +YQ PPS+ NHI + SPA R +ENR Sbjct: 1436 NHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1495 Query: 1599 TSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRR 1658 SPSKSPFL S MKMQK P VP S + P QPP IRR+ITFPPGSVEA+QPVLKQRR+ Sbjct: 1496 MSPSKSPFLPS-MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRK 1554 Query: 1659 LTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVE 1718 +T KDI TPEAWRVMMSLKSGLLAESTWALDTINILLYDD+++ TFNLSQL G LELLVE Sbjct: 1555 ITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVE 1614 Query: 1719 YFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEE--ELLGPKLEEE 1776 YFR+CLI+IFGIL EYEVGDP Q+ L S + G+EEE E + E+E Sbjct: 1615 YFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDE 1674 Query: 1777 EEEEV----VENDEE--IAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDK 1830 E+EE E+DE+ IA + D A + K SKFDKLP+KIV+KN+ FVVD SDK Sbjct: 1675 EDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDK 1734 Query: 1831 LGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTP 1889 LGRVQEF+SGLLHW++GGGDTTEHIQTHFESK E+ P R P P A RK EG Sbjct: 1735 LGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKG 1792 Query: 1890 GTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSH 1949 + +Q+ EK I AT+DD+LS R L ED + ESSKFPFGI A+SH Sbjct: 1793 DSEEQQ--------EKSIIATIDDVLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSH 1842 Query: 1950 RNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLL 2009 RNIK+LEDEP S+DETPLCT+ WQDSLAKRC+CVSN +RSLSFVPGND EMSKHPGL+L Sbjct: 1843 RNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVL 1902 Query: 2010 ILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISG 2069 ILGKLILLHH+HPERK+AP TYEKEE++D+GV+C+K EWWWDCLE+LR+NTLVTLANISG Sbjct: 1903 ILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISG 1962 Query: 2070 QLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQD 2129 QLDLS Y ESICLP+LDGLLHW VCPSAEAQDPF T+GPN+VLSPQRLVLETL KLSIQD Sbjct: 1963 QLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQD 2022 Query: 2130 NNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQK 2189 NNVDLILATPPFSR EK Y+T+VR++ DRKNPVCREM++ LL+NLAQGD+LAARAIAVQK Sbjct: 2023 NNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQK 2082 Query: 2190 GSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHS 2249 GSIGNL+ FLED + Q+QQSQ +L+HMQ PP EP SVDMM RAA+ALLA+A+VDEN S Sbjct: 2083 GSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRS 2142 Query: 2250 EFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQ 2284 EF L+E RLLDIS+S ++NSLV+ VICDVLF IGQ Sbjct: 2143 EFLLHEGRLLDISISAVLNSLVASVICDVLFQIGQ 2177 Score = 52.0 bits (123), Expect = 7e-06 Identities = 230/1051 (21%), Positives = 313/1051 (29%), Gaps = 216/1051 (20%) Query: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568 + P+ PPHQQ A + QQ Q Q Q QQQQ Q P Sbjct: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75 Query: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625 + S A PQP Q P + G QA SK G Sbjct: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126 Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 ED + P G + +G G P V+ G G A F+ + Sbjct: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176 Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745 P GP G G SP G + + M P N Sbjct: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227 Query: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804 GY P YS P G GG GS G GG Sbjct: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271 Query: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864 GG A+ A +A AGG G GG G YG L Sbjct: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310 Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918 + P Q G GM PGG + A A A + QN+ P P + Sbjct: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361 Query: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967 NQ MM G+ P Y +S + P P S + G A+ M Sbjct: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417 Query: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018 MG +PA + + GTP + S K +LY +G P Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 Query: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKE---------IGGLTQV 1067 + G P GR P + + ++ + G Q Sbjct: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQ 537 Query: 1068 NKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQ 1127 + + + ++ + S +Q Q P D+ +SQ Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ--------------PQQDMSQEGYGTRSQ 583 Query: 1128 PKIQP---------------PS--PAGSGSMQG-PQTPQST-------SSSMAEGGDLKP 1162 P + P PS P SGS+ P ++T S S + GD Sbjct: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643 Query: 1163 P-----TPASTPH-SQIPPLP---------GMSRSNSVGIQDAFNDGSDSTFQKRNSMTP 1207 P +P ++PH S IP P G ++S S I A GS Q S + Sbjct: 644 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703 Query: 1208 NPGYQPSMNTSDM------MGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD-PY 1260 + + P+++ S M M P YG + P P S G + G+ Sbjct: 704 SSSH-PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 762 Query: 1261 SRAAGP-GLGNVAMGPRQHYPYGGPYDRV--RTEPGIGPEGNMSTGAPQPNLMPSNPDSG 1317 S ++G G GP+ +Y Y V + G GP +S PS P G Sbjct: 763 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQP-CG 821 Query: 1318 MYSPSRYPPQQQQQQ-----QQRHDSYGNQFSTQGTPS-GSPFPS------QQTTMYQQQ 1365 R P Q + S QG P G P P+ + Q Sbjct: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQA 881 Query: 1366 QQNYKRPMDGTYGPPAKRHEGEM-YSVPYS---TGQGQPQQQQLPPAQPQPASQQQAAQP 1421 N + G++ P G M S PYS Q PP PA +A Sbjct: 882 AANSAQSRQGSF--PGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939 Query: 1422 SPQQDVYNQYGNAYPATATAATERRPAGGPQ 1452 D+ + + P A + + G PQ Sbjct: 940 VGLADMMSPGESKLPLPLKA--DGKEEGTPQ 968 Score = 50.1 bits (118), Expect = 3e-05 Identities = 219/1053 (20%), Positives = 324/1053 (30%), Gaps = 183/1053 (17%) Query: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511 PP+ Q + ++ H QQQ QQ QQQ Q Q Q Sbjct: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69 Query: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567 Q Q P S S AP P QH ++ + QA P + + Sbjct: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128 Query: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614 AP + + A Y P +QQ P + +GS A + Sbjct: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188 Query: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666 A GGQ+ + + S ++ GS+D L EG + PG S G Sbjct: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248 Query: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723 G G G V + A+ A + +G G+ Sbjct: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 Query: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771 PR G +M P S+++++ G QR Q P ++P L Sbjct: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 Query: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831 + P M SYG +Y P P+ P + +AG A G Sbjct: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407 Query: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 MG G M Q + SH +M GP M GS M P Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463 Query: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940 + ++ Q + + + Q+ P YP GG G P G+ +MAGM Sbjct: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515 Query: 941 INPQ---GPPYSMGGTMANNSAGM----AASPE----------MMGLGDVKLTPATKMNN 983 PQ P Y G G + P+ + + P M+ Sbjct: 516 QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQ 575 Query: 984 KADGT----PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMT 1039 + GT P K + E+ + L +L G + + A G T Sbjct: 576 EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635 Query: 1040 NLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQC 1099 + P + S L+ + + + VG++ S + + I Sbjct: 636 SSQGDQSNPA---QSPFSPHASPHLSSIPGGPSPSPVGS--PVGSNQSRSGPISPASIP- 689 Query: 1100 LYAFECKIERGEDPPPDIFAAADSKKSQPKI-QPPSPAGSGSMQGPQ-TPQSTSSSMAEG 1157 G PP + S P + Q P P G M G Q PQ + Sbjct: 690 ----------GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 739 Query: 1158 GDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNT 1217 G P+ +PH P PG + S+FQ+ NS + Y P M+ Sbjct: 740 G------PSMSPH----PSPGGQMHAGI-----------SSFQQSNS---SGTYGPQMSQ 775 Query: 1218 SDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGP 1275 G S P Y + A S P G N M G S+ G LG + Sbjct: 776 YGPQGNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 832 Query: 1276 RQHYPYGGPYDRVR-TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334 Q+ P+ G + + PG+ +G G P MP+ + + Q Sbjct: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP----MPTVNRKAQEAAAAVMQAAANSAQS 888 Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394 R S+ + S SP+ Q N + T PP + S S Sbjct: 889 RQGSFPGMNQSGLMASSSPY---------SQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939 Query: 1395 TGQG---QPQQQQLPPAQPQPASQQQAAQPSPQ 1424 G P + +LP P A ++ P P+ Sbjct: 940 VGLADMMSPGESKLP--LPLKADGKEEGTPQPE 970 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 1992 bits (5160), Expect = 0.0 Identities = 1168/2324 (50%), Positives = 1407/2324 (60%), Gaps = 255/2324 (10%) Query: 25 KKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-KELQDGAESNGGG 83 ++ +QQQ+++ + + A G GP + PQ G K+ G +++ G Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Query: 84 GGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSA 139 + G A P + G P L T+ P GGGGG Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP----------- 166 Query: 140 AAALPP--PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG--GLEPY 195 AA+P YG P P A QHGGQQSPG+ + S G Sbjct: 167 -AAVPEFNNYYGSAAPASGGPGGRAGPC----FDQHGGQQSPGMGMMHSASAAAAGAPGS 221 Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255 P QNSH+ G+PN Q N Y P Y+ GG G G Sbjct: 222 MDPLQNSHE-GYPNSQCNHY-----------PGYSRPGAGGGGGGGGGGGGGSG------ 263 Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315 G GGGG A G G A GY G G Sbjct: 264 ----------------GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 Query: 316 ---YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372 S Q GG GP GAA+ + AAA ++ G QR P + Sbjct: 308 GVLSSPRQQGGGMMMGPGG-----GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362 Query: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNP-YSQQQGPP---SGPQQGHGYPGQPYGSQTPQ 428 L +P P + YGG+ P YS PP S PQ G G Q Sbjct: 363 QLLTSPSPMM----------RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ--- 409 Query: 429 RYPMTMQGRAQSAMG---GLSYTQQIPPYGQQGPSGY-----GQQGQTPYYNQQSPHPQQ 480 Q A +G G Y P + + G G T +Q SP Sbjct: 410 ------QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463 Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ-----PSQPPHQQSPAPYP 535 PH+QP QS P S PP Q+ + P + YP Sbjct: 464 VMKRPQLYGMGSNPHSQPQ-----QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518 Query: 536 SQQ----STTQQHPQSQPPYSQPQAQSPY--QQQQP---QQPAPSTLSQQAAYPQPQSQQ 586 QQ +T ++ PP Q S Y Q QQP QQP P L QA Y QSQQ Sbjct: 519 QQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 578 Query: 587 SQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSI 646 R+ P Q++SQ+ +G++ S P + K ED+NL Q RPSSLPDLSGSI Sbjct: 579 ---------RYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSI 627 Query: 647 DDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPAS 705 DDLP GTE LS VS SG +SSQG+QSNPAQSPFSPH SPHL I G PSPSPVGSP Sbjct: 628 DDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVG 687 Query: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQY 762 QSRSGP+SPA++PG+QMPP+PP QS+S HP+++QS + Q+RG+M QRNPQM QY Sbjct: 688 SNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY 747 Query: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNA 821 Q G ++SP GGQ+H G+ S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A Sbjct: 748 GPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSA 807 Query: 822 NYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP---- 877 +Y G GI+ A QMHGQ P G +P GRM A M NRP+ NM++M P Sbjct: 808 SYSGPGPGMGIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPG 864 Query: 878 ---QVGSGMCPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQG 933 Q G GM PP +NRK QE A A M AANS Q+R +P MNQ G+M + PY Q Sbjct: 865 MSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP 924 Query: 934 INSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTES 993 +N+ + ++N Q PPYSM M N+SA +MM G+ KL K + K +GTP+ ES Sbjct: 925 MNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPES 984 Query: 994 KSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYR 1053 KSKKSSSSTTT EKITK+YELG EPERK+WVDRYL F EE+ +++LPAVG+KPLDL+R Sbjct: 985 KSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFR 1044 Query: 1054 LYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDP 1113 LYV VKEIGGL QVNKNKKWRELATNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+P Sbjct: 1045 LYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEP 1104 Query: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHS 1171 PP++F+ D+KK QPK+QPPSPA SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH Sbjct: 1105 PPEVFSTGDTKK-QPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHG 1163 Query: 1172 QIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKD 1231 Q+ P+ G RS+++ + D F+D SDS+F KRNSMTPN YQ M+ D+MGRM YEPNK Sbjct: 1164 QMTPMQG-GRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK- 1221 Query: 1232 PYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTE 1291 DPF + P G +P+ + G + Y++ Sbjct: 1222 -----------DPFGGMRKVP--GSSEPF----------MTQGQMPNSSMQDMYNQ---- 1254 Query: 1292 PGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSG 1351 P G MS + GM ++P +RH+ YG Q+ QG PSG Sbjct: 1255 ---SPSGAMS-------------NLGMGQRQQFP--YGASYDRRHEPYGQQYPGQGPPSG 1296 Query: 1352 SP-FPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQP 1410 P + Q +Y QQ NYKR MDG YGPPAKRHEG+MY++ YS Sbjct: 1297 QPPYGGHQPGLYPQQP-NYKRHMDGMYGPPAKRHEGDMYNMQYS---------------- 1339 Query: 1411 QPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGT 1470 S QQ++YNQYG +Y + +RRP Q Q+P+ + R+R+ P G Sbjct: 1340 -----------SQQQEMYNQYGGSY-----SGPDRRPI---QGQYPYPYSRERMQGP-GQ 1379 Query: 1471 NAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTD 1530 +PPQMMGGP+Q+S+ Q MW RNDM Y Y NRQ G Q P Y G+NRTD Sbjct: 1380 IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD 1439 Query: 1531 EMLHTDQRANHEGSWPSHGTRQPPY-GPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPA 1589 +M+ DQR NHE WPSH +++ PY SA + P+TRPP +YQ PPS+ NHI + SPA Sbjct: 1440 DMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPA 1499 Query: 1590 PLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEAT 1649 R +ENR SPSKSPFL S MKMQK P VP S + P QPP IRR+ITFPPGSVEA+ Sbjct: 1500 SFQRSLENRMSPSKSPFLPS-MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEAS 1558 Query: 1650 QPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQL 1709 QPVLKQRR++T KDI TPEAWRVMMSLKSGLLAESTWALDTINILLYDD+++ TFNLSQL Sbjct: 1559 QPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQL 1618 Query: 1710 PGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEE--E 1767 G LELLVEYFR+CLI+IFGIL EYEVGDP Q+ L S + G+EEE E Sbjct: 1619 SGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAE 1678 Query: 1768 LLGPKLEEEEEEEV----VENDEE--IAFSGKDKPASENSEEKLISKFDKLPVKIVQKND 1821 + E+EE+EE E+DE+ IA + D A + K SKFDKLP+KIV+KN+ Sbjct: 1679 CIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNN 1738 Query: 1822 PFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRK 1880 FVVD SDKLGRVQEF+SGLLHW++GGGDTTEHIQTHFESK E+ P R P P A RK Sbjct: 1739 LFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRK 1798 Query: 1881 HVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFP 1940 EG + +Q+ EK I AT+DD+LS R L ED + ESSKFP Sbjct: 1799 K--EQEGKGDSEEQQ--------EKSIIATIDDVLSARPGALPEDANPGPQT--ESSKFP 1846 Query: 1941 FGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFE 2000 FGI A+SHRNIK+LEDEP S+DETPLCT+ WQDSLAKRC+CVSN +RSLSFVPGND E Sbjct: 1847 FGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAE 1906 Query: 2001 MSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENT 2060 MSKHPGL+LILGKLILLHH+HPERK+AP TYEKEE++D+GV+C+K EWWWDCLE+LR+NT Sbjct: 1907 MSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNT 1966 Query: 2061 LVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLE 2120 LVTLANISGQLDLS Y ESICLP+LDGLLHW VCPSAEAQDPF T+GPN+VLSPQRLVLE Sbjct: 1967 LVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLE 2026 Query: 2121 TLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSL 2180 TL KLSIQDNNVDLILATPPFSR EK Y+T+VR++ DRKNPVCREM++ LL+NLAQGD+L Sbjct: 2027 TLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDAL 2086 Query: 2181 AARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLA 2240 AARAIAVQKGSIGNL+ FLED + Q+QQSQ +L+HMQ PP EP SVDMM RAA+ALLA Sbjct: 2087 AARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLA 2146 Query: 2241 LAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQ 2284 +A+VDEN SEF L+E RLLDIS+S ++NSLV+ VICDVLF IGQ Sbjct: 2147 MARVDENRSEFLLHEGRLLDISISAVLNSLVASVICDVLFQIGQ 2190 Score = 68.2 bits (165), Expect = 9e-11 Identities = 241/1129 (21%), Positives = 331/1129 (29%), Gaps = 229/1129 (20%) Query: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568 + P+ PPHQQ A + QQ Q Q Q QQQQ Q P Sbjct: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75 Query: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625 + S A PQP Q P + G QA SK G Sbjct: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126 Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 ED + P G + +G G P V+ G G A F+ + Sbjct: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176 Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745 P GP G G SP G + + M P N Sbjct: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227 Query: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804 GY P YS P G GG GS G GG Sbjct: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271 Query: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864 GG A+ A +A AGG G GG G YG L Sbjct: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310 Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918 + P Q G GM PGG + A A A + QN+ P P + Sbjct: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361 Query: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967 NQ MM G+ P Y +S + P P S + G A+ M Sbjct: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417 Query: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018 MG +PA + + GTP + S K +LY +G P Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 Query: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076 + G P GR P + + ++ G + W+E Sbjct: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSG------DATWKET 531 Query: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136 + S +Q Q Y+ + P P P + P + Sbjct: 532 FWLMPPQYGQQGVSGYCQQGQQPYYS--------QQPQP------------PHLPPQAQY 571 Query: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV-GIQDAFNDGS 1195 Q PQ S G +PP P+ + L R +S+ + + +D Sbjct: 572 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLP 631 Query: 1196 DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPY-GSMRKAPGSDPFMSSGQGPNG 1254 T +S G S + + P+ P+ S+ P P + S G N Sbjct: 632 TGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSP-VGSPVGSNQ 690 Query: 1255 GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNL--MPS 1312 P S A+ PG M P+ P G+ S + P L P Sbjct: 691 SRSGPISPASIPG---SQMPPQ-------------------PPGSQSESSSHPALSQSPM 728 Query: 1313 NPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRP 1372 + G + ++ PQ Q YG Q Q PS SP PS M+ + Sbjct: 729 PQERGFMAGTQRNPQMAQ--------YGPQ---QTGPSMSPHPSPGGQMHAGISSFQQSN 777 Query: 1373 MDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPA-QPQPASQQQAAQPSPQQDVYNQY 1431 GTYGP ++ G PPA P++ P NQ Sbjct: 778 SSGTYGPQMSQY-------------GPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQM 824 Query: 1432 GNAYPATATAATE--RRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASA 1489 P+ A R P+ G QN+ PF P M +S Sbjct: 825 HGQGPSQPCGAVPLGRMPSAGMQNR-PF--------------------PGNMSSMTPSSP 863 Query: 1490 EVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHG 1549 ++QQG G T N +++ + Q A +R N G S Sbjct: 864 GMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSF----PGMNQSGLMASSS 919 Query: 1550 TRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENR 1598 P S+ + PP Y P+M N A + P E++ Sbjct: 920 PYSQPMNNSSSLMNTQAPP---YSMAPAMVNSSAASVGLADMMSPGESK 965 Score = 48.9 bits (115), Expect = 6e-05 Identities = 223/1049 (21%), Positives = 330/1049 (31%), Gaps = 162/1049 (15%) Query: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511 PP+ Q + ++ H QQQ QQ QQQ Q Q Q Sbjct: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69 Query: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567 Q Q P S S AP P QH ++ + QA P + + Sbjct: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128 Query: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614 AP + + A Y P +QQ P + +GS A + Sbjct: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188 Query: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666 A GGQ+ + + S ++ GS+D L EG + PG S G Sbjct: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248 Query: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723 G G G V + A+ A + +G G+ Sbjct: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 Query: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771 PR G +M P S+++++ G QR Q P ++P L Sbjct: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 Query: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831 + P M SYG +Y P P+ P + +AG A G Sbjct: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407 Query: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 MG G M Q + SH +M GP M GS M P Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463 Query: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940 + ++ Q + + + Q+ P YP GG G P G+ +MAGM Sbjct: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515 Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSS 1000 PQ +G A E L + G S+ + Sbjct: 516 QYPQ-----------QQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH 564 Query: 1001 STTTNEKITKLYELGGEPERKMWVDRYLAFTEEK-AMGMTNLPAVG----RKPLDLYRLY 1055 + + + +P++ M + Y ++ A G N + +P L L Sbjct: 565 LPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLS 624 Query: 1056 VSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPP 1115 S+ ++ T+ + + + G S+ A S + I G P P Sbjct: 625 GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS---PHLSSIPGGPSPSP 681 Query: 1116 DIFAAADSKKSQPKIQPPSPAG-SGSMQGPQTPQSTSSSMAEGGDLKPPTP------AST 1168 + +Q + P SPA GS PQ P S S S + + P P A T Sbjct: 682 ---VGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGT 738 Query: 1169 PH----SQIPPL---PGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221 +Q P P MS S G Q S+FQ+ NS + Y P M+ Sbjct: 739 QRNPQMAQYGPQQTGPSMSPHPSPGGQ---MHAGISSFQQSNS---SGTYGPQMSQYGPQ 792 Query: 1222 GRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGPRQHY 1279 G S P Y + A S P G N M G S+ G LG + Q+ Sbjct: 793 GNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 Query: 1280 PYGGPYDRVR-TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDS 1338 P+ G + + PG+ +G G P MP+ + + Q R S Sbjct: 850 PFPGNMSSMTPSSPGMSQQGGPGMGPP----MPTVNRKAQEAAAAVMQAAANSAQSRQGS 905 Query: 1339 YGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQG 1398 + + S SP+ Q N + T PP + S S G Sbjct: 906 FPGMNQSGLMASSSPY---------SQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLA 956 Query: 1399 ---QPQQQQLPPAQPQPASQQQAAQPSPQ 1424 P + +LP P A ++ P P+ Sbjct: 957 DMMSPGESKLP--LPLKADGKEEGTPQPE 983 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 1974 bits (5113), Expect = 0.0 Identities = 1167/2368 (49%), Positives = 1403/2368 (59%), Gaps = 303/2368 (12%) Query: 25 KKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLG-KELQDGAESNGGG 83 ++ +QQQ+++ + + A G GP + PQ G K+ G +++ G Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Query: 84 GGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSA 139 + G A P + G P L T+ P GGGGG Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP----------- 166 Query: 140 AAALPP--PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG--GLEPY 195 AA+P YG P P A QHGGQQSPG+ + S G Sbjct: 167 -AAVPEFNNYYGSAAPASGGPGGRAGPC----FDQHGGQQSPGMGMMHSASAAAAGAPGS 221 Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255 P QNSH+ G+PN Q N Y P Y+ GG G G Sbjct: 222 MDPLQNSHE-GYPNSQCNHY-----------PGYSRPGAGGGGGGGGGGGGGSG------ 263 Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315 G GGGG A G G A GY G G Sbjct: 264 ----------------GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 Query: 316 ---YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372 S Q GG GP GAA+ + AAA ++ G QR P + Sbjct: 308 GVLSSPRQQGGGMMMGPGG-----GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362 Query: 373 PLARTPQPSSPMDQMGKMRPQPYGGTNP-YSQQQGPP---SGPQQGHGYPGQPYGSQTPQ 428 L +P P + YGG+ P YS PP S PQ G G Q Sbjct: 363 QLLTSPSPMM----------RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ--- 409 Query: 429 RYPMTMQGRAQSAMG---GLSYTQQIPPYGQQGPSGY-----GQQGQTPYYNQQSPHPQQ 480 Q A +G G Y P + + G G T +Q SP Sbjct: 410 ------QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463 Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ-----PSQPPHQQSPAPYP 535 PH+QP QS P S PP Q+ + P + YP Sbjct: 464 VMKRPQLYGMGSNPHSQPQ-----QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP 518 Query: 536 SQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQ 595 QQ Q Q Y Q Q Q PY QQPQ P L QA Y QSQQ Sbjct: 519 QQQMPPQYGQQGVSGYCQ-QGQQPYYSQQPQPPH---LPPQAQYLPSQSQQ--------- 565 Query: 596 RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEG 655 R+ P Q++SQ+ +G++ S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE Sbjct: 566 RYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEA 623 Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPL 714 LS VS SG +SSQG+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+ Sbjct: 624 TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPI 683 Query: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSAL 771 SPA++PG+QMPP+PP QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++ Sbjct: 684 SPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743 Query: 772 SPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAG 830 SP GGQ+H G+ S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803 Query: 831 GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGM 883 GI+ A QMHGQ P G +P GRM A M NRP+ NM++M P Q G GM Sbjct: 804 GIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGM 860 Query: 884 CPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMIN 942 PP +NRK QE A A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N Sbjct: 861 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMN 920 Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSK------ 996 Q PPYSM M N+SA +MM G+ KL K + K +GTP+ ESKSK Sbjct: 921 TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQ 980 Query: 997 -----------------------------------------------KSSSSTTTNEKIT 1009 KSSSSTTT EKIT Sbjct: 981 GISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKIT 1040 Query: 1010 KLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNK 1069 K+YELG EPERK+WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIGGL QVNK Sbjct: 1041 KVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNK 1100 Query: 1070 NKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPK 1129 NKKWRELATNLNVGTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D+KK QPK Sbjct: 1101 NKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKK-QPK 1159 Query: 1130 IQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMSRSNSVGI 1187 +QPPSPA SGS+QGPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G RS+++ + Sbjct: 1160 LQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISV 1218 Query: 1188 QDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMS 1247 D F+D SDS+F KRNSMTPN YQ M+ D+MGRM YEPNK DPF Sbjct: 1219 HDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK------------DPFGG 1266 Query: 1248 SGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQP 1307 + P G +P+ + G + Y++ P G MS Sbjct: 1267 MRKVP--GSSEPF----------MTQGQMPNSSMQDMYNQ-------SPSGAMS------ 1301 Query: 1308 NLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSP-FPSQQTTMYQQQQ 1366 + GM ++P +RH+ YG Q+ QG PSG P + Q +Y QQ Sbjct: 1302 -------NLGMGQRQQFP--YGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQP 1352 Query: 1367 QNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQD 1426 NYKR MDG YGPPAKRHEG+MY++ YS S QQ+ Sbjct: 1353 -NYKRHMDGMYGPPAKRHEGDMYNMQYS---------------------------SQQQE 1384 Query: 1427 VYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486 +YNQYG +Y + +RRP Q Q+P+ + R+R+ P G +PPQMMGGP+Q Sbjct: 1385 MYNQYGGSY-----SGPDRRPI---QGQYPYPYSRERMQGP-GQIQTHGIPPQMMGGPLQ 1435 Query: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWP 1546 +S+ Q MW RNDM Y Y NRQ G Q P Y G+NRTD+M+ DQR NHE WP Sbjct: 1436 SSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWP 1495 Query: 1547 SHGTRQPPY-GPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSP 1605 SH +++ PY SA + P+TRPP +YQ PPS+ NHI + SPA R +ENR SPSKSP Sbjct: 1496 SHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSP 1555 Query: 1606 FLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIG 1665 FL S MKMQK P VP S + P QPP IRR+ITFPPGSVEA+QPVLKQRR++T KDI Sbjct: 1556 FLPS-MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIV 1614 Query: 1666 TPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLI 1725 TPEAWRVMMSLKSGLLAESTWALDTINILLYDD+++ TFNLSQL G LELLVEYFR+CLI Sbjct: 1615 TPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLI 1674 Query: 1726 EIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEE--ELLGPKLEEEEEEEV-- 1781 +IFGIL EYEVGDP Q+ L S + G+EEE E + E+EE+EE Sbjct: 1675 DIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDS 1734 Query: 1782 --VENDEE--IAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEF 1837 E+DE+ IA + D A + K SKFDKLP+KIV+KN+ FVVD SDKLGRVQEF Sbjct: 1735 EKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEF 1794 Query: 1838 DSGLLHWRIGGGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTPGTTDQEG 1896 +SGLLHW++GGGDTTEHIQTHFESK E+ P R P P A RK EG + +Q+ Sbjct: 1795 NSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKGDSEEQQ- 1851 Query: 1897 PPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILE 1956 EK I AT+DD+LS R L ED + ESSKFPFGI A+SHRNIK+LE Sbjct: 1852 -------EKSIIATIDDVLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSHRNIKLLE 1902 Query: 1957 DEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLIL 2016 DEP S+DETPLCT+ WQDSLAKRC+CVSN +RSLSFVPGND EMSKHPGL+LILGKLIL Sbjct: 1903 DEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLIL 1962 Query: 2017 LHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPY 2076 LHH+HPERK+AP TYEKEE++D+GV+C+K EWWWDCLE+LR+NTLVTLANISGQLDLS Y Sbjct: 1963 LHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAY 2022 Query: 2077 PESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLIL 2136 ESICLP+LDGLLHW VCPSAEAQDPF T+GPN+VLSPQRLVLETL KLSIQDNNVDLIL Sbjct: 2023 TESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLIL 2082 Query: 2137 ATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLL 2196 ATPPFSR EK Y+T+VR++ DRKNPVCREM++ LL+NLAQGD+LAARAIAVQKGSIGNL+ Sbjct: 2083 ATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLI 2142 Query: 2197 GFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYES 2256 FLED + Q+QQSQ +L+HMQ PP EP SVDMM RAA+ALLA+A+VDEN SEF L+E Sbjct: 2143 SFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEG 2202 Query: 2257 RLLDISVSPLMNSLVSQVICDVLFLIGQ 2284 RLLDIS+S ++NSLV+ VICDVLF IGQ Sbjct: 2203 RLLDISISAVLNSLVASVICDVLFQIGQ 2230 Score = 57.8 bits (138), Expect = 1e-07 Identities = 236/1087 (21%), Positives = 324/1087 (29%), Gaps = 217/1087 (19%) Query: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568 + P+ PPHQQ A + QQ Q Q Q QQQQ Q P Sbjct: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75 Query: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625 + S A PQP Q P + G QA SK G Sbjct: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126 Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 ED + P G + +G G P V+ G G A F+ + Sbjct: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176 Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745 P GP G G SP G + + M P N Sbjct: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227 Query: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804 GY P YS P G GG GS G GG Sbjct: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271 Query: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864 GG A+ A +A AGG G GG G YG L Sbjct: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310 Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918 + P Q G GM PGG + A A A + QN+ P P + Sbjct: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361 Query: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967 NQ MM G+ P Y +S + P P S + G A+ M Sbjct: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417 Query: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018 MG +PA + + GTP + S K +LY +G P Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477 Query: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKE---------IGGLTQV 1067 + G P GR P + + ++ + G Q Sbjct: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQ 537 Query: 1068 NKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQ 1127 + + + ++ + S +Q Q P D+ +SQ Sbjct: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ--------------PQQDMSQEGYGTRSQ 583 Query: 1128 PKIQP---------------PS--PAGSGSMQG-PQTPQST-------SSSMAEGGDLKP 1162 P + P PS P SGS+ P ++T S S + GD Sbjct: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643 Query: 1163 P-----TPASTPH-SQIPPLP---------GMSRSNSVGIQDAFNDGSDSTFQKRNSMTP 1207 P +P ++PH S IP P G ++S S I A GS Q S + Sbjct: 644 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703 Query: 1208 NPGYQPSMNTSDM------MGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD-PY 1260 + + P+++ S M M P YG + P P S G + G+ Sbjct: 704 SSSH-PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 762 Query: 1261 SRAAGP-GLGNVAMGPRQHYPYGGPYDRV--RTEPGIGPEGNMSTGAPQPNLMPSNPDSG 1317 S ++G G GP+ +Y Y V + G GP +S PS P G Sbjct: 763 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQP-CG 821 Query: 1318 MYSPSRYPPQQQQQQ-----QQRHDSYGNQFSTQGTPS-GSPFPS------QQTTMYQQQ 1365 R P Q + S QG P G P P+ + Q Sbjct: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQA 881 Query: 1366 QQNYKRPMDGTYGPPAKRHEGEM-YSVPYS---TGQGQPQQQQLPPAQPQPASQQQAAQP 1421 N + G++ P G M S PYS Q PP PA +A Sbjct: 882 AANSAQSRQGSF--PGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939 Query: 1422 SPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481 D+ + + P A + P+++ + +S PP N+P Sbjct: 940 VGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPP---TPGNLPVPSP 996 Query: 1482 GGPIQAS 1488 P AS Sbjct: 997 MSPSSAS 1003 Score = 55.1 bits (131), Expect = 8e-07 Identities = 223/1068 (20%), Positives = 330/1068 (30%), Gaps = 182/1068 (17%) Query: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511 PP+ Q + ++ H QQQ QQ QQQ Q Q Q Sbjct: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69 Query: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567 Q Q P S S AP P QH ++ + QA P + + Sbjct: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128 Query: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614 AP + + A Y P +QQ P + +GS A + Sbjct: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188 Query: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666 A GGQ+ + + S ++ GS+D L EG + PG S G Sbjct: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248 Query: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723 G G G V + A+ A + +G G+ Sbjct: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 Query: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771 PR G +M P S+++++ G QR Q P ++P L Sbjct: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365 Query: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831 + P M SYG +Y P P+ P + +AG A G Sbjct: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407 Query: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 MG G M Q + SH +M GP M GS M P Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463 Query: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940 + ++ Q + + + Q+ P YP GG G P G+ +MAGM Sbjct: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515 Query: 941 INPQ---GPPYSMGGTMANNSAGM----AASPE----------MMGLGDVKLTPATKMNN 983 PQ P Y G G + P+ + + P M+ Sbjct: 516 QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQ 575 Query: 984 KADGT----PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMT 1039 + GT P K + E+ + L +L G + + A G T Sbjct: 576 EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635 Query: 1040 NLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQC 1099 + P + S L+ + + + VG++ S + + I Sbjct: 636 SSQGDQSNPA---QSPFSPHASPHLSSIPGGPSPSPVGS--PVGSNQSRSGPISPASIP- 689 Query: 1100 LYAFECKIERGEDPPPDIFAAADSKKSQPKI-QPPSPAGSGSMQGPQ-TPQSTSSSMAEG 1157 G PP + S P + Q P P G M G Q PQ + Sbjct: 690 ----------GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 739 Query: 1158 GDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNT 1217 G P+ +PH P PG + S+FQ+ NS + Y P M+ Sbjct: 740 G------PSMSPH----PSPGGQMHAGI-----------SSFQQSNS---SGTYGPQMSQ 775 Query: 1218 SDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGP 1275 G S P Y + A S P G N M G S+ G LG + Sbjct: 776 YGPQGNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 832 Query: 1276 RQHYPYGGPYDRVR-TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334 Q+ P+ G + + PG+ +G G P MP+ + + Q Sbjct: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP----MPTVNRKAQEAAAAVMQAAANSAQS 888 Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394 R S+ + S SP+ Q N + T PP + S S Sbjct: 889 RQGSFPGMNQSGLMASSSPY---------SQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939 Query: 1395 TGQG---QPQQQQLPPAQPQPASQQQAAQP-SPQQDVYNQYGNAYPAT 1438 G P + +LP ++ QP S +D Y+ G + P T Sbjct: 940 VGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT 987 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 123 bits (309), Expect = 2e-27 Identities = 238/953 (24%), Positives = 314/953 (32%), Gaps = 156/953 (16%) Query: 7 PAAASSLGN-----------PPPPPPSELKKAEQQQREE---AGGEAAAAAAAERGEMKA 52 P AA + GN PP PP + + E AG + A +RGE Sbjct: 314 PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373 Query: 53 AAGQESEGPAVGPP----QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAG 108 ++GP GPP P GK A G G GA GP G AG Sbjct: 374 QGHAGAQGPP-GPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432 Query: 109 PRPALNNNLTEP-----------PGGGGGGSSDGV-GAPPHSAAAALPPPAYGFGQPYGR 156 P N EP PG G DG G+P A LP A G P R Sbjct: 433 -EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFR 491 Query: 157 ---SPSAVAAAAAAVFHQQHGGQQSPGLAALQSG-----GGGGLEPYAGPQQNSHDHGFP 208 P+ + + G P AA + G GG G+ G G P Sbjct: 492 GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP 551 Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ 268 + R PP P S PRG G G+ P + Q Sbjct: 552 GPPGSQGESGRPG--PPGP----SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605 Query: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP--QDGGAG 326 G G GP G P PT P ++ T P +G QG PG +GGP ++G G Sbjct: 606 GPPGKNGETGPQ----GPPGPTG-PGGDKGDTGPPGPQGLQGLPG---TGGPPGENGKPG 657 Query: 327 K-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP-------LARTP 378 + GP A GA A A ++ +PG GG G P A P Sbjct: 658 EPGPKGDA----GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713 Query: 379 QP----------SSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP-------QQGHGYPGQP 421 P P ++ G P P G +G P GP + G P P Sbjct: 714 GPPGAAGTPGLQGMPGERGGLGSPGPKG-------DKGEPGGPGADGVPGKDGPRGPTGP 766 Query: 422 YGSQTPQRYPMTMQGRAQSAMGGLSYTQQIP----PYGQQGPSGY----GQQGQTPYYNQ 473 G P P + G++ + P G GP+G+ GQ G+ + Sbjct: 767 IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGE 826 Query: 474 QSPHPQQQQ--PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531 + ++ + PP PP + A P P Q + + P P + P Sbjct: 827 RGAPGEKGEGGPPGVAGPPGGSGPAGP-----PGPQGVKGERGSPGGPGAAGFPGARGLP 881 Query: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591 P S + P P P + P P S A P ++ A Sbjct: 882 GPPGSNGNPGPPGPSGSPGKDGPPGPAG-NTGAPGSPGVSGPKGDAGQP---GEKGSPGA 937 Query: 592 YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM 651 P P ++ + + P M +G + +S LSG + P Sbjct: 938 QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSG--ERGPP 995 Query: 652 GTEGALSPGVSTSGISSSQGEQSNPAQSPF-----SP--------HTSPHLPGIRG--PS 696 G +G PG+ +G + G NP SP + SP PG G Sbjct: 996 GPQGL--PGL--AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051 Query: 697 PSPVGSPASVAQSR--SGPLSPAAVP---GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751 P PVG PA + R SGP PA P G++ P P + D + I RG Sbjct: 1052 PGPVG-PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRG 1110 Query: 752 YMQRNPQMP----------QYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG- 800 + NP P SP P P PSG G + +G GP+G Sbjct: 1111 F-PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGH-PGPIGPPGPRGN 1168 Query: 801 -GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850 G+ G +G G+P QP P A P G G G GG+ G G PY Sbjct: 1169 RGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAG--GFAPY 1219 Score = 112 bits (280), Expect = 4e-24 Identities = 254/1070 (23%), Positives = 333/1070 (31%), Gaps = 181/1070 (16%) Query: 7 PAAASSLGNPPPP----PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA 62 P + G+P P PP E +A G + A + G+ E Sbjct: 185 PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL 244 Query: 63 VGPPQ---PLGKELQDGAESNGG--GGGGGAGSGGGPGAE-----PDLKNSNGNAGPRPA 112 GPP P G G + + G G G G G PG + P + G GPR A Sbjct: 245 PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304 Query: 113 L-NNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF-GQPYGRSPSAVAAAAAAVFH 170 PG G +DG PP GF G P + A + + Sbjct: 305 PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364 Query: 171 QQHGGQQSP-GLAALQS-GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA 228 G+ P G A Q G G+ G + G P A PP PA Sbjct: 365 PGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP-----GLMGARGPPGPA 419 Query: 229 YALSSP--RGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGT 286 A +P RGG G A G P A A+ G G G A G Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG-- 477 Query: 287 PQPTATPTLNQLLTSPSSARGYQGY--PGGDYSGGPQDGGAGKGPADMASQCWGAAAAAA 344 L + RG G+ P G + G AG+ A + GAA Sbjct: 478 ------------LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525 Query: 345 AAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR-------TPQPSSPMDQMGKMR-PQPYG 396 G + +P PGS G G P ++ P PS P Q G M P P G Sbjct: 526 RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG 585 Query: 397 --GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYP-MTMQGRAQSAMGGLSYTQQIPP 453 G + ++G P GP G PG+ G PQ P T G + G P Sbjct: 586 NDGAPGKNGERGGPGGPGP-QGPPGK-NGETGPQGPPGPTGPGGDKGDTG---------P 634 Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ--SQPPQL 511 G QG G G P N + P + + P A ++ P + P L Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694 Query: 512 QSSQPPYSQQPSQ----PPHQQSPAPYPSQQSTTQQH---PQSQPPYSQPQAQSPYQQQQ 564 + P + + PP A P Q + P + + P Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV 754 Query: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP-------PPQELSQDSFGSQAS--SA 615 P + P + P P Q + P P E + A A Sbjct: 755 PGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGA 814 Query: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSN 675 P GG+ + + P ++G P G G P G+ +G Sbjct: 815 PGQNGEPGGKGERGAPGEKGEGGPPGVAG-----PPGGSGPAGP-PGPQGVKGERGSPGG 868 Query: 676 PAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDS 735 P + F PG RG P P GS GP P+ PG PP P+G + + Sbjct: 869 PGAAGF--------PGARG-LPGPPGS-----NGNPGPPGPSGSPGKDGPP-GPAGNTGA 913 Query: 736 IMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSP--RQPSGGQIHTGMGSYQQNSM 793 P ++ P+ + QPG SP + P G G+ + Sbjct: 914 PGSPGVSG----------------PKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI-TGAR 956 Query: 794 GSYGPQG-----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQ- 840 G GP G G GPQG G +P N L P G+AG G G Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016 Query: 841 -------------------MHGQPGIP--PYGTLPPGRMSHA-SMGNR----PYGPNMAN 874 +G PG P P PPG + A G+R P GP A Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP--AG 1074 Query: 875 MPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRP--PGYPN----MNQGGMMG--- 925 P GS P P G ET + P PG P Q G +G Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG 1134 Query: 926 ----------TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP 965 +GPP G + G I P GP + G + S G P Sbjct: 1135 PAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184 Score = 100 bits (250), Expect = 1e-20 Identities = 237/1032 (22%), Positives = 313/1032 (30%), Gaps = 139/1032 (13%) Query: 17 PPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ-----PLGK 71 P PP + + Q + G+ R GQ + GPP P G Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148 Query: 72 E----------LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121 + ++ G G G G GP P G+ G + PP Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG-----SPGYQGPP 203 Query: 122 GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL 181 G G G PP + + P G GR + G PG Sbjct: 204 GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGI----KGPAGIPGF 259 Query: 182 AALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTP 239 ++ G + G + G P + + P + P P RG G P Sbjct: 260 PGMKGHRG-----FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP 314 Query: 240 GS-------GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTAT 292 G+ GA + G PP +A S A+ G G G + A G +P Sbjct: 315 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEP--G 372 Query: 293 PTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG 352 P + P G G PGG GP G P M ++ A A A GG Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGP--AGIPGAPGLMGARGPPGPAGANGAPGLRGG 430 Query: 353 AQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412 A + PG +G G+P P + G+ G + G P P Sbjct: 431 AGE--------PGKNGAKGEP--------GPRGERGEAGIPGVPGAKGEDGKDGSPGEP- 473 Query: 413 QGHGYPGQPYGSQTPQ-RYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYY 471 +G PG P R P G G P G +G +G + P Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNG-IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532 Query: 472 NQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531 P P S P P +P P QP P P Sbjct: 533 PGMRGMPGSPGGPGSDGKPG--PPGSQGESGRPGPPGPSGPRGQPGVMGFPG--PKGNDG 588 Query: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591 AP + + P Q P + P Q P P P PQ Q Sbjct: 589 APGKNGERGGPGGPGPQGPPGKNGETGP--QGPPGPTGPGGDKGDTGPPGPQGLQGLPGT 646 Query: 592 YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSL---PDLSGSIDD 648 PP + G + + + GG+ D + P L P L G Sbjct: 647 GG----PPGENGKPGEPGPKGDA--GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP 700 Query: 649 L-PMGTEGALSP-----GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGS 702 P G +GA P T G+ GE+ PG +G P G Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS-----------PGPKGDKGEPGGP 749 Query: 703 PASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM-QRNPQMPQ 761 A + GP P G PP P D + IA RG +R P Sbjct: 750 GADGVPGKDGPRGPTGPIG---PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPP 806 Query: 762 YSSPQPGSALSPRQPSGGQIHTGMGSYQQNS-MGSYGPQGGQ-----YGPQG-----GYP 810 + PG+ +P G G + G GP GG GPQG G P Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP 866 Query: 811 RQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTL----PPGRMSHASMGNR 866 P P A G+ G P G+ G G PG P G+ PPG + Sbjct: 867 GGPGAAGFPGAR----GLPG---PPGSNGN-PGPPG--PSGSPGKDGPPGPAGNTGAPGS 916 Query: 867 P--YGP-NMANMPPQVGS-GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMN--- 919 P GP A P + GS G PPG +A A + PPG P Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPG----PLGIAGITGARGLAG-PPGMPGPRGSP 971 Query: 920 --QGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTP 977 QG +G P G++ G PQG P + GT G +P GL +P Sbjct: 972 GPQGVKGESGKPGANGLSGERGPPGPQGLP-GLAGTA--GEPGRDGNPGSDGLPGRDGSP 1028 Query: 978 ATKMNNKADGTP 989 K + +G+P Sbjct: 1029 GGKGDRGENGSP 1040 Score = 89.4 bits (220), Expect = 4e-17 Identities = 138/524 (26%), Positives = 166/524 (31%), Gaps = 75/524 (14%) Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGE-----MKAAAGQ 56 A P PP PP + Q E GG + ++GE G+ Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757 Query: 57 ES-EGPA--VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--P 111 + GP +GPP P G Q G G GG G GP P + G GP P Sbjct: 758 DGPRGPTGPIGPPGPAG---QPG--DKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812 Query: 112 ALNNNLTEP--------PGGGGGGSSDGVGAPPHSAAAALPPPAYGF----GQPYGRSPS 159 EP PG G G GV PP + A PP G G P G P Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG--PG 870 Query: 160 AVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNR 219 A A G +PG G G + GP N+ G P P Sbjct: 871 AAGFPGARGLPGPPGSNGNPGPPG--PSGSPGKDGPPGPAGNTGAPGSPGVS----GPKG 924 Query: 220 SAYPPPAPAYALSSPRGGTPG----SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMG 275 A P + G PG +G A G PP S + G G Sbjct: 925 DAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPG 984 Query: 276 GGGPSAAGGGTPQPTATPTLNQLLTSP--SSARGYQGYPGGDYS-GGPQDGGAGKGPADM 332 G S G P P P L P G G PG D S GG D G P Sbjct: 985 ANGLSGE-RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP 1043 Query: 333 ASQCWGAAAAAAAAAAASGGAQQRSHHAPM-SPGSSGGGGQPLARTPQPSSPMDQMGKMR 391 + A SG + P +PG +G G P P P G+ Sbjct: 1044 GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRG-----APGPQGPRGDKGETG 1098 Query: 392 PQPYGGT--------NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMG 443 + G NP + P+G Q G PG P G + P S Sbjct: 1099 ERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG-PAGPRGPV---------GPSGPP 1148 Query: 444 GLSYTQQIP-PYGQQGPSG-YGQQGQTPYYNQQSP-HPQQQQPP 484 G T P P G GP G G++G ++ SP HP Q PP Sbjct: 1149 GKDGTSGHPGPIGPPGPRGNRGERG-----SEGSPGHPGQPGPP 1187 Score = 65.9 bits (159), Expect = 4e-10 Identities = 103/380 (27%), Positives = 123/380 (32%), Gaps = 59/380 (15%) Query: 3 AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESE--- 59 A+ P S GNP PP PS + AG A + G K AGQ E Sbjct: 877 ARGLPGPPGSNGNPGPPGPSG-SPGKDGPPGPAGNTGAPGSPGVSGP-KGDAGQPGEKGS 934 Query: 60 ----GPAVGPPQPLGKELQDGAESNGG-----------GGGGGAGSGGGPGAEPDLKNSN 104 GP G P PLG GA G G G G G PGA L Sbjct: 935 PGAQGPP-GAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGAN-GLSGER 992 Query: 105 GNAGPR--PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVA 162 G GP+ P L E PG G SDG+ G P G+ Sbjct: 993 GPPGPQGLPGLAGTAGE-PGRDGNPGSDGLPGRD--------------GSPGGKGDRGEN 1037 Query: 163 AAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAY 222 + A H G P A +SG G P AGP G +R A Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGP-AGPAGAPGPAG-----------SRGAP 1085 Query: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAA 282 P P +G T GAA G + P + + S + Q G+ G GP Sbjct: 1086 GPQGP----RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141 Query: 283 GGGTPQPTATPTLNQL-LTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341 G + P T P RG +G G + S G GP C G Sbjct: 1142 VGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVG 1201 Query: 342 AAAAAAAASGGAQQRSHHAP 361 AAA A G ++ AP Sbjct: 1202 AAAIAGI---GGEKAGGFAP 1218 Score = 58.5 bits (140), Expect = 7e-08 Identities = 128/535 (23%), Positives = 174/535 (32%), Gaps = 118/535 (22%) Query: 515 QPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP-----PYSQPQAQSPYQQQQPQQPA 569 QPP + P++PP+ Q P Q P+ P P P Q P P Sbjct: 90 QPPTA--PTRPPNGQGP-----------QGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG 136 Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQR---------FPPPQELSQDSFGSQASSAPSMTS 620 P + + PQ+ Q +Y + +P P S P Sbjct: 137 PPGICESCP-TGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG 195 Query: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680 S G Q Q+ PS P G GA+ P SG + GE P + Sbjct: 196 SPGYQGPPGEPGQAGPSG-----------PPGPPGAIGP----SGPAGKDGESGRPGRP- 239 Query: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQ----SRSGPLSPAAVPG----NQMP------- 725 P PGI+GP+ P G P R+G PG N +P Sbjct: 240 -GERGLPGPPGIKGPAGIP-GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPG 297 Query: 726 PRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGM 785 P P G P + ++ A+ + + P P PG+A P P G + G Sbjct: 298 PMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP-PGTAGFPGSP-GAKGEVGP 355 Query: 786 GSYQQNSMGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGINPMGAG 838 S GS G G G+ GPQG G P P N P GG MG Sbjct: 356 AG----SPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP----------GGKGEMGPA 401 Query: 839 GQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPNMANMPPQVGSGMCPP--------PGG 889 G + G PG+ MG R P GP AN P + G P PG Sbjct: 402 G-IPGAPGL---------------MGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP 445 Query: 890 MNRKTQETAVAMHVAANSI-QNRPPGYPNMN--------QGGMMGTGPPYGQGINSMAGM 940 + + + A ++ PG P N +G GP GI G Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505 Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKS 995 +G P G A G P G+ + +P ++ G P ++ +S Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560 Score = 51.6 bits (122), Expect = 9e-06 Identities = 99/381 (25%), Positives = 122/381 (32%), Gaps = 106/381 (27%) Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--------PSP 699 ++P G A+ P T+ G Q P P P PGI G + P Sbjct: 78 EIPFGECCAVCPQPPTAPTRPPNG------QGPQGPKGDPGPPGIPGRNGDPGIPGQPGS 131 Query: 700 VGSPASVAQSRSGPLSP---------------------AAVPGNQMPPRPPSGQSDSIMH 738 GSP S P P A PG PP PP G + H Sbjct: 132 PGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPP-GPPGTSGH 190 Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSPQ----PGSALSPRQPSGGQIHTGMGSYQQNSMG 794 P S GY Q P P + P P A+ P P+G +G + G Sbjct: 191 PGSPGSP-----GY-QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPG-RPGERG 243 Query: 795 SYGPQG--------------------GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGI 832 GP G G+ G +G G P N LP N G G + Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN----GAPGPM 299 Query: 833 NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNR 892 P GA G+ G+PG+P + S G +P P PP G PG Sbjct: 300 GPRGAPGE-RGRPGLPGAAGARGNDGARGSDG-QPGPPG----PP----GTAGFPGSPGA 349 Query: 893 KTQETAVAMHVAANSIQNRPPGYPNMNQG-GMMGTGPPYGQGINSMAGMINPQGPP---Y 948 K + P G P N G G P G AG P GPP Sbjct: 350 KGEVG--------------PAGSPGSNGAPGQRGEPGPQGH-----AGAQGPPGPPGING 390 Query: 949 SMGGTMANNSAGMAASPEMMG 969 S GG AG+ +P +MG Sbjct: 391 SPGGKGEMGPAGIPGAPGLMG 411 Score = 40.0 bits (92), Expect = 0.026 Identities = 122/523 (23%), Positives = 155/523 (29%), Gaps = 109/523 (20%) Query: 1132 PPSPAGSGSMQ---GPQTPQSTSSSMAEGG----DLKPPTPASTPHSQIPPLPG------ 1178 PP P G G + GP PQ GG + KP P + P PG Sbjct: 619 PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAG 678 Query: 1179 -------MSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKD 1231 + + G++ + PG + M G + Sbjct: 679 APGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738 Query: 1232 PYGSMRK--APGSD--PFMSSGQGPNGGMGDP--------YSRAAGPGLGNVAMGPRQHY 1279 P G + PG+D P +GP G +G P PGL +A GPR Sbjct: 739 PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA-GPR--- 794 Query: 1280 PYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSY 1339 G P +R T P GP G GAP N P R P ++ + Sbjct: 795 --GSPGERGETGPP-GPAG--FPGAPGQNGEPGG------KGERGAPGEKGE-------- 835 Query: 1340 GNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRH-EGEMYSVPYSTGQG 1398 G G P GS G GPP + +GE S G Sbjct: 836 GGPPGVAGPPGGS----------------------GPAGPPGPQGVKGERGSPGGPGAAG 873 Query: 1399 QPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQF--P 1456 P + LP P S P P + G PA T A GP+ P Sbjct: 874 FPGARGLP---GPPGSNGNPGPPGPSGSP-GKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929 Query: 1457 FQFGRDRVSAPPG----------TNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTY 1506 + G PPG T A+ P M GP QG + + Sbjct: 930 GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGP---RGSPGPQGV----KGESGK 982 Query: 1507 NYANRQSTGSAPQGP-------AYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSA 1559 AN S P GP G D +D +GS G R P A Sbjct: 983 PGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGA 1042 Query: 1560 PVPPMTRPPPSNYQPP-PSMQNHIPQVSSPAPLPRPMENRTSP 1601 P P PP P S + PA P P +R +P Sbjct: 1043 PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP 1085 Score = 38.1 bits (87), Expect = 0.100 Identities = 92/384 (23%), Positives = 118/384 (30%), Gaps = 55/384 (14%) Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNS----VGIQ 1188 P P G QGP P + S G++ P + IP PG+ + G Sbjct: 371 PGPQGHAGAQGPPGPPGINGSPGGKGEMGP--------AGIPGAPGLMGARGPPGPAGAN 422 Query: 1189 DAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSS 1248 A + +N PG + + + G + GS PG +P + Sbjct: 423 GAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGS----PG-EPGANG 477 Query: 1249 GQGPNGGMGDPYSRA-AGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQP 1307 G G G P R AGP GP GP G +G G P Sbjct: 478 LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDG--VPGGPGM 535 Query: 1308 NLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS--GSPFPSQQTTMYQQQ 1365 MP +P G S + P Q + R G +G P G P P + Sbjct: 536 RGMPGSP-GGPGSDGKPGPPGSQGESGRPGPPGPS-GPRGQPGVMGFPGPKGNDGAPGKN 593 Query: 1366 QQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQG---------QPQ-QQQLPPAQPQPASQ 1415 + G GPP K E P TG G PQ Q LP P Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653 Query: 1416 QQAAQPSPQQDVYNQYGNAYPATATAATERRPAG-----------GPQNQFPFQFGRDRV 1464 + +P P+ D A A ER P G GP P G Sbjct: 654 GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP----PGPEGGKGA 709 Query: 1465 SAPP------GTNAQQNMPPQMMG 1482 + PP GT Q MP + G Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGG 733 Score = 34.7 bits (78), Expect = 1.1 Identities = 89/394 (22%), Positives = 122/394 (30%), Gaps = 82/394 (20%) Query: 1105 CKIERGEDPPPDI-FAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPP 1163 C + + P P+I F + QP P P QGP+ GD P Sbjct: 67 CDDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIP 126 Query: 1164 TPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGR 1223 +P S P PG+ S G Q+ Y P ++ D+ Sbjct: 127 GQPGSPGS--PGPPGICESCPTGPQN---------------------YSPQYDSYDVKSG 163 Query: 1224 MSYEPNKDPYGSMRKAPGSDPFMSSG-QGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG 1282 ++ G + PG P G GP G G P S PG P Q P G Sbjct: 164 VA-------VGGLAGYPG--PAGPPGPPGPPGTSGHPGS-PGSPGYQGPPGEPGQAGPSG 213 Query: 1283 --GPYDRVRTEPGIGPEGNMS-TGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSY 1339 GP + G +G G P +P P G+ P+ P + + D Sbjct: 214 PPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP--GIKGPAGIPGFPGMKGHRGFDGR 271 Query: 1340 GNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKR-HEGEMYSVPYSTGQG 1398 + G P + +N +G GP R GE +G Sbjct: 272 NGEKGETGAPG-------------LKGENGLPGENGAPGPMGPRGAPGE---------RG 309 Query: 1399 QPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNA-YPATATAATERRPAGGP------ 1451 +P A+ ++ QP P G A +P + A E PAG P Sbjct: 310 RPGLPGAAGARGNDGARGSDGQPGPP----GPPGTAGFPGSPGAKGEVGPAGSPGSNGAP 365 Query: 1452 -QNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGP 1484 Q P G PPG PP + G P Sbjct: 366 GQRGEPGPQGHAGAQGPPG-------PPGINGSP 392 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 119 bits (298), Expect = 3e-26 Identities = 184/719 (25%), Positives = 250/719 (34%), Gaps = 133/719 (18%) Query: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA------QQRFGA 273 +A P A A L +PR PGS PPP + A+ ++ A +R G Sbjct: 13 AARTPAARAPGLLTPR--PPGSPRP------PPPVTPAALRVLGAAGAVGRKPLAERAGG 64 Query: 274 MGGGG--PSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDG-GAGKGPA 330 +GG SA G + T + N P+S RG + P + S GP G G Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124 Query: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPM------ 384 +A A G A + + +S G+ P TP P+ Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184 Query: 385 DQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGG 444 ++G RP P P P GP++ S+ P R SA GG Sbjct: 185 TEVGLPRPAPSARPRP------PTEGPRKSVSS-----ASEHSTTEPSPAARRRPSAGGG 233 Query: 445 L---------SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSP------HPQQQQPPYSQQP 489 L S + + GPS G + +Q P P Q PP Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293 Query: 490 P-----SQTPHAQPSYQQQPQSQPP--------------QLQSSQPPYSQQPSQPPHQQS 530 P S +P A PS QSQ P QL + P PS PP Q+ Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353 Query: 531 ----PAPYPSQQSTTQQHPQSQ-----------------PPYSQPQAQSPYQQQQPQQPA 569 PA PSQ +T+ P Q PP + P P Q P PA Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413 Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRF-PPPQELSQDSFGSQASSAPSMTSSKGGQEDM 628 LS A P PQ+ + Q F PPP Q F AS S +++ Q Sbjct: 414 SPPLSPLAT-PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472 Query: 629 NLS---LQSRPS--SLPDLSGSIDDLPMGTEGALSP-------------GVSTSGISSSQ 670 +L+ LQ PS + P +S S P +P ++T + + Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532 Query: 671 GEQSN-PAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPP 729 ++ P Q+PFSP S LP +P P P A P SP A P Q P RPP Sbjct: 533 SPPASFPGQAPFSPSAS--LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 590 Query: 730 SGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQ 789 + D +S++ R + P P S P S LS +G H+ + Sbjct: 591 TPGPD---------TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG---HSSSATST 638 Query: 790 QNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIP 848 + Y GP+GG P +A A +P+A G P+ G PG P Sbjct: 639 PEELRGY-----DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA----FRGAPGAP 688 Score = 83.6 bits (205), Expect = 2e-15 Identities = 193/787 (24%), Positives = 253/787 (32%), Gaps = 122/787 (15%) Query: 5 VAPAAASSLGNPPPPPPSELKK-------AEQQQREEAGGEAAAAA--AAERGEMKAAAG 55 + P S PPP P+ L+ + E AGG A +A R +AG Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84 Query: 56 QESEGPAVGPPQ-------PLGKELQDGAESNGGGGGGGAGSG--GGPG----AEPDLKN 102 S PA PP P K G S+ G G G G G AE + Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144 Query: 103 SNGNAGP-RPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAA---LPPPAYGFGQPYGRSP 158 P R AL+ G G+ A AA LP PA +P R P Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS-ARP--RPP 201 Query: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGG-------GLEPYAGPQQNSHDHGFPNHQ 211 + + + + + SP S GGG L A P + G P+ + Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG-PSAR 260 Query: 212 YNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271 P + P P AL P+ P AA A G P SSS A+ S S+ Q + Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG---PLSSSPLATPSPSAALQSQA 317 Query: 272 GAMGGGGPSAAGG----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK 327 P ++ TP P A P SPS+ Q P + Q + Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPP-------SPSAPPSLQTLPSPPATPPSQATTSLG 370 Query: 328 GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA--RTPQPSSPMD 385 P A+ + + + A A P+ S PL+ TP P +P Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430 Query: 386 QMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL 445 + P+ PPS P Q P P S P T +A ++ Sbjct: 431 LAVHLLQAPFSP---------PPSPPVQA---PFSPPASP-PVSPSATPPSQAPPSLAAP 477 Query: 446 SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505 Q+PP P P +P PQ PP PP Q A+P P Sbjct: 478 PL--QVPPSPPASP---------PMSPSATPPPQA--PPPLAAPPLQL--AKP-----PP 517 Query: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQP 565 PP L + PP PS P AP+ S + PP + P +P Q P Sbjct: 518 QAPPALAT--PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575 Query: 566 QQPAPSTLSQQAAYPQPQSQQSQQ-----TAYSQQRFPPPQE-----LSQDSFGSQASSA 615 PA TL P P S A + PPP LS +SSA Sbjct: 576 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635 Query: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLS-----------GSIDDLPM-GTEGALSPGVST 663 S G D + S PD G L G GA P Sbjct: 636 TSTPEELRGY-DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 694 Query: 664 SGISSSQG----------EQSNPAQSPFSPHTSPHLPGIRGPSPSPVG-SPASVAQSRSG 712 +G S+ G E + PA P SP G + + + G S S Q+R G Sbjct: 695 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 754 Query: 713 PLSPAAV 719 L A+ Sbjct: 755 ELPLGAL 761 Score = 52.4 bits (124), Expect = 5e-06 Identities = 127/549 (23%), Positives = 169/549 (30%), Gaps = 83/549 (15%) Query: 1113 PPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ 1172 PP A A S + PSP+ + Q P T +T S + L P P + P Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346 Query: 1173 IPP-LPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQP-SMNTSDMMGRMSYEPNK 1230 PP L + + A T Q +S P+P P + ++ P + Sbjct: 347 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406 Query: 1231 DPYGSMRKAPGSDPFMSSGQGPNG----GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYD 1286 P P S S Q PN + P+S P + P P P Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSP----PASPPVS 461 Query: 1287 RVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQ 1346 T P P S AP + PS P S SPS PP Q Sbjct: 462 PSATPPSQAPP---SLAAPPLQVPPSPPASPPMSPSATPPPQAP---------------- 502 Query: 1347 GTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLP 1406 P +P Q P+ PPA G+ P ++ P P Sbjct: 503 -PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPLATPPP 560 Query: 1407 PAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERR-PAGGPQNQFPFQFGRDRVS 1465 A P A+ PSP PA+ T RR P GP VS Sbjct: 561 QAPPVLAAPLLQVPPSP------------PASPTLQAPRRPPTPGPDTS---------VS 599 Query: 1466 APPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGR-NDMTYNYANRQSTGSAPQGPAYH 1524 P T A PP P S G G + T + S P+G A Sbjct: 600 GPRLTLALAPGPPP----PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655 Query: 1525 GVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSM----QN 1580 E+ A H +W S G P AP P+ PP + + + Sbjct: 656 SPPPDAEL-----AACHPAAW-SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 709 Query: 1581 HIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDIT 1640 P+ ++PAP P SP G AG A A + P R Sbjct: 710 EGPESATPAP------GALDPGPSPGTSGGKAAAGAG--------AGASSRSPKQARLGE 755 Query: 1641 FPPGSVEAT 1649 P G+++A+ Sbjct: 756 LPLGALQAS 764 Score = 48.1 bits (113), Expect = 1e-04 Identities = 142/601 (23%), Positives = 185/601 (30%), Gaps = 107/601 (17%) Query: 1119 AAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPT------------PA 1166 AA P + P P GS P TP + A G + P P Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 1167 STPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTP--NPGYQPSMNTSDMMGRM 1224 S P + G S N A G + K S P +PG +G+ Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132 Query: 1225 SYEPNKDPY---GSMRKAPGSDPFMSSGQ----GPNGGMGDPY----SRAAGP--GLGNV 1271 + + G +AP + + GP G P SRAAG GL Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192 Query: 1272 AMGPRQHYPYGGPYDRVR-------TEPGIGPEGNMSTGA----PQPNLMPSNPDSGMYS 1320 A R P GP V TEP S G P + S+ + + S Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA-TPLSS 251 Query: 1321 PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPP 1380 P+R P S +GTP PSQ Q RP T PP Sbjct: 252 PARSGP-----------------SARGTPRAPAHPSQPKPKGLQAL----RPPQVT--PP 288 Query: 1381 AKRHE---GEMYSVPYST-GQGQPQQQQLPPAQP----------QPASQQQAAQPSPQQD 1426 K G + S P +T Q Q PP P Q A+ A PSP Sbjct: 289 RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348 Query: 1427 VYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486 Q + PAT + G P Q F +P T Q PP + P+Q Sbjct: 349 PSLQTLPSPPATPPSQATTS-LGSPTLQATHSFLPSPPLSPLATPPPQ-APPALALPPLQ 406 Query: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWP 1546 A + +PQ P V+ + P Sbjct: 407 APPSPPASPPL-------------SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA--P 451 Query: 1547 SHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPF 1606 PP PSA P ++ PPS PP + SP P + T P ++P Sbjct: 452 FSPPASPPVSPSATPP--SQAPPSLAAPP------LQVPPSPPASPPMSPSATPPPQAPP 503 Query: 1607 LHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGT 1666 + +Q A PP A PA PP+ + + PP S P L M + T Sbjct: 504 PLAAPPLQLAKPPPQA---PPALATPPL--QALPSPPASFPGQAP-FSPSASLPMSPLAT 557 Query: 1667 P 1667 P Sbjct: 558 P 558 Score = 40.0 bits (92), Expect = 0.026 Identities = 66/251 (26%), Positives = 82/251 (32%), Gaps = 29/251 (11%) Query: 107 AGPRP--ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPP---AYGFGQPYGRSPSAV 161 +GPR AL PP + G HS++A P Y G G + S Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658 Query: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGGGGLE--PYAGPQQNSHDHGFPNHQYNSYYPNR 219 A A H + A + G L P GP G + Y Sbjct: 659 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP-------GSADGLCTIYETEG 711 Query: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGP 279 PAP P GT G AAA AG A +SS S Q R G + G Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAAAGAG----------AGASSRSPKQARLGELPLGAL 761 Query: 280 SAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGA 339 A+ Q + TL LL + A G G G GG GGA +D W Sbjct: 762 QAS---VVQHLLSRTL--LLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAE 816 Query: 340 AAAAAAAAAAS 350 + + AS Sbjct: 817 LLSPLDESRAS 827 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 117 bits (292), Expect = 2e-25 Identities = 176/685 (25%), Positives = 242/685 (35%), Gaps = 123/685 (17%) Query: 225 PAPAYALSSPRGGTPGS----GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG-P 279 P P + P TP + GAA A G KP +R G +GG P Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKP---------------LAERAGGIGGATIP 71 Query: 280 SAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP-QDGGAGKGPADMASQCWG 338 +A P T+ P P+S RG + P + S GP G G Sbjct: 72 ESAPRAGPTRTSRP--------PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPS------SPMDQMGKMRP 392 +A A G A + + +S G+ P TP P+ + ++G RP Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183 Query: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL------- 445 P P P GP++ S+ P R SA GGL Sbjct: 184 APSARPRP------PTEGPRK-----SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232 Query: 446 --SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSP------HPQQQQPPYSQQPP-----SQ 492 S + + GPS G + +Q P P Q PP P S Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292 Query: 493 TPHAQPSYQQQPQ-SQPPQLQSSQPPYSQQPSQPPHQQSPA-PYPSQQSTTQQHPQ---- 546 +P A PS P S PP LQ+ P P+ PP Q + + P+ Q+T P Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSP----PATPPSQATTSLGSPTLQATHSFLPSPPLS 348 Query: 547 ---SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF-PPPQE 602 + PP + P P Q P PA LS A P PQ+ + Q F PPP Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFSPPPSP 407 Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLS---LQSRPS--SLPDLSGSIDDLPMGTEGAL 657 Q F AS S +++ Q +L+ LQ PS + P +S S P Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467 Query: 658 S-------------PGVSTSGISSSQGEQSN-PAQSPFSPHTSPHLPGIRGPSPSPVGSP 703 + P ++T + + ++ P Q+PFSP S LP +P P P Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS--LPMSPLATPPPQAPP 525 Query: 704 ASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS 763 A P SP A P Q P RPP+ D +S++ R + P P Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPD---------TSVSGPRLTLALAPGPPPPP 576 Query: 764 SPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANY 823 S P S LS +G H+ + + Y GP+GG P +A A + Sbjct: 577 SRSPSSTLSGPDLAG---HSSSATSTPEELRGY-----DSGPEGGAAASPPPDAELAACH 628 Query: 824 PSAGMAGGINPMGAGGQMHGQPGIP 848 P+A G P+ G PG P Sbjct: 629 PAAWSRGPAPPLA----FRGAPGAP 649 Score = 74.7 bits (182), Expect = 1e-12 Identities = 176/750 (23%), Positives = 233/750 (31%), Gaps = 170/750 (22%) Query: 6 APAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGP 65 +P AS P P L+ + EE A A +R + A A +++ GP G Sbjct: 107 SPGRASGTTRPGPLGQKGLRISA----EETVARGKATEAPKRSALSAGARRDTSGPTPGT 162 Query: 66 PQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGG 125 P P A G E L +A PRP TE P Sbjct: 163 PSPAMARRSRAA-----------------GTEVGLPRPAPSARPRPP-----TEGPRKSV 200 Query: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQ 185 +S+ P AA R PSA GG Q P +L Sbjct: 201 SSASEHSTTEPSPAAR--------------RRPSA------------GGGLQRPASRSLS 234 Query: 186 SGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAA 245 S P + P ++ P+ + P + P P AL P+ P AA Sbjct: 235 SSA----TPLSSPARSG-----PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 285 Query: 246 AAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA 305 A G P SSS A+ S S+ P P+A P+L L + P++ Sbjct: 286 ALG---PLSSSPLATPSPSA--------------------PPSPSAPPSLQTLPSPPATP 322 Query: 306 RGYQGYPGGDYSGGPQDGGAGKG-PADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP 364 P G P A+ + + + A A P+ Sbjct: 323 --------------PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 368 Query: 365 GSSGGGGQPLA--RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPY 422 S PL+ TP P +P + P+ PPS P Q P P Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP---------PPSPPVQA---PFSPP 416 Query: 423 GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQ 482 S P T +A ++ Q+PP P P +P PQ Sbjct: 417 ASP-PVSPSATPPSQAPPSLAAPPL--QVPPSPPASP---------PMSPSATPPPQA-- 462 Query: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542 PP PP Q A+P P PP L + PP PS P AP+ S Sbjct: 463 PPPLAAPPLQL--AKP-----PPQAPPALAT--PPLQALPSPPASFPGQAPFSPSASLPM 513 Query: 543 QHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQ-----TAYSQQRF 597 + PP + P +P Q P PA TL P P S A + Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573 Query: 598 PPPQE-----LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLS--------- 643 PPP LS +SSA S G D + S PD Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-DSGPEGGAAASPPPDAELAACHPAAW 632 Query: 644 --GSIDDLPM-GTEGALSPGVSTSGISSSQG----------EQSNPAQSPFSPHTSPHLP 690 G L G GA P +G S+ G E + PA P SP Sbjct: 633 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 692 Query: 691 GIRGPSPSPVG-SPASVAQSRSGPLSPAAV 719 G + + + G S S Q+R G L A+ Sbjct: 693 GGKAAAGAGAGASSRSPKQARLGELPLGAL 722 Score = 48.5 bits (114), Expect = 7e-05 Identities = 125/546 (22%), Positives = 169/546 (30%), Gaps = 93/546 (17%) Query: 1121 ADSKKSQPK------IQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIP 1174 A + SQPK ++PP P +SS +A PP+P++ P Q Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315 Query: 1175 PLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQP-SMNTSDMMGRMSYEPNKDPY 1233 P P + + A T Q +S P+P P + ++ P + P Sbjct: 316 PSPPATPPS-----QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370 Query: 1234 GSMRKAPGSDPFMSSGQGPNG----GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR 1289 P S S Q PN + P+S P + P P P Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSP----PASPPVSPSA 425 Query: 1290 TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP 1349 T P P S AP + PS P S SPS PP Q P Sbjct: 426 TPPSQAPP---SLAAPPLQVPPSPPASPPMSPSATPPPQAP-----------------PP 465 Query: 1350 SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQ 1409 +P Q P+ PPA G+ P ++ P P A Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPLATPPPQAP 524 Query: 1410 PQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERR-PAGGPQNQFPFQFGRDRVSAPP 1468 P A+ PSP PA+ T RR P GP VS P Sbjct: 525 PVLAAPLLQVPPSP------------PASPTLQAPRRPPTPGPDTS---------VSGPR 563 Query: 1469 GTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGR-NDMTYNYANRQSTGSAPQGPAYHGVN 1527 T A PP P S G G + T + S P+G A Sbjct: 564 LTLALAPGPPP----PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619 Query: 1528 RTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSM----QNHIP 1583 E+ A H +W S G P AP P+ PP + + + P Sbjct: 620 PDAEL-----AACHPAAW-SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673 Query: 1584 QVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPP 1643 + ++PAP P SP G AG A A + P R P Sbjct: 674 ESATPAP------GALDPGPSPGTSGGKAAAGAG--------AGASSRSPKQARLGELPL 719 Query: 1644 GSVEAT 1649 G+++A+ Sbjct: 720 GALQAS 725 Score = 47.4 bits (111), Expect = 2e-04 Identities = 140/597 (23%), Positives = 185/597 (30%), Gaps = 138/597 (23%) Query: 1119 AAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTP--------ASTPH 1170 AA P + P P GS P TP + A G + P A+ P Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 1171 SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTP--NPGYQPSMNTSDMMGRMSYEP 1228 S P G +R++ A G + K S P +PG +G+ Sbjct: 73 SA--PRAGPTRTSR---PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 127 Query: 1229 NKDPY---GSMRKAPGSDPFMSSGQ----GPNGGMGDPY----SRAAGP--GLGNVAMGP 1275 + + G +AP + + GP G P SRAAG GL A Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187 Query: 1276 RQHYPYGGPYDRVR-------TEPGIGPEGNMSTGA----PQPNLMPSNPDSGMYSPSRY 1324 R P GP V TEP S G P + S+ + + SP+R Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA-TPLSSPARS 246 Query: 1325 PPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRH 1384 P S +GTP PSQ Q RP T PP K Sbjct: 247 GP-----------------SARGTPRAPAHPSQPKPKGLQAL----RPPQVT--PPRKDA 283 Query: 1385 E---GEMYSVPYSTGQ--------GQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGN 1433 G + S P +T P Q LP P SQ + SP + + Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343 Query: 1434 AYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQ 1493 + P + P P Q P + APP A + P P Sbjct: 344 SPPLS--------PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP--------- 386 Query: 1494 QGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQP 1553 Q N + + Q+ S P P Q Sbjct: 387 -----QAPNALAVHLL--QAPFSPPPSPPV----------------------------QA 411 Query: 1554 PYGP--SAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPME-NRTSPSKSPFLHSG 1610 P+ P S PV P PP Q PPS+ QV P PM + T P ++P + Sbjct: 412 PFSPPASPPVSPSATPPS---QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 468 Query: 1611 MKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTP 1667 +Q A PP A PA PP+ + + PP S P L M + TP Sbjct: 469 PPLQLAKPPPQA---PPALATPPL--QALPSPPASFPGQAP-FSPSASLPMSPLATP 519 Score = 40.0 bits (92), Expect = 0.026 Identities = 66/251 (26%), Positives = 82/251 (32%), Gaps = 29/251 (11%) Query: 107 AGPRP--ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPP---AYGFGQPYGRSPSAV 161 +GPR AL PP + G HS++A P Y G G + S Sbjct: 560 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619 Query: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGGGGLE--PYAGPQQNSHDHGFPNHQYNSYYPNR 219 A A H + A + G L P GP G + Y Sbjct: 620 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP-------GSADGLCTIYETEG 672 Query: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGP 279 PAP P GT G AAA AG A +SS S Q R G + G Sbjct: 673 PESATPAPGALDPGPSPGTSGGKAAAGAG----------AGASSRSPKQARLGELPLGAL 722 Query: 280 SAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGA 339 A+ Q + TL LL + A G G G GG GGA +D W Sbjct: 723 QAS---VVQHLLSRTL--LLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAE 777 Query: 340 AAAAAAAAAAS 350 + + AS Sbjct: 778 LLSPLDESRAS 788 Score = 34.7 bits (78), Expect = 1.1 Identities = 59/280 (21%), Positives = 89/280 (31%), Gaps = 64/280 (22%) Query: 650 PMGTEGALSPG-VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIR----GPSPSPVGSPA 704 P G PG + G+ S E ++ +P S G R GP+P SPA Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG-TPSPA 166 Query: 705 SVAQSRS-GPLSPAAVPGNQMPPRPPS-GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762 +SR+ G P PRPP+ G S+ S ++ Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------------------EH 206 Query: 763 SSPQPGSALSPRQPSGGQIHT------GMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYN 816 S+ +P A R +GG + + +S GP +P QP Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266 Query: 817 AL-----PNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPG--------------- 856 L P P A + P+ + P PP + PP Sbjct: 267 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326 Query: 857 ---------RMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 + +H+ + + P P +A PPQ + PP Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSP-LATPPPQAPPALALPP 365 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 112 bits (281), Expect = 3e-24 Identities = 255/1061 (24%), Positives = 329/1061 (31%), Gaps = 202/1061 (19%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAV--- 63 P S P PP + + Q E G A+ RG +G A Sbjct: 180 PMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPG 239 Query: 64 -----GPPQPLGKELQDGAESNGG--------------GGGGGAGSGGGPGAEPDLKNSN 104 GPP P G G G G G AG G PG+ P + Sbjct: 240 RPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS-PGENGAP 298 Query: 105 GNAGPRPALNNNLTEP--PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVA 162 G GPR L P PG G +DG + AA PP G P G P AV Sbjct: 299 GQMGPR-GLPGERGRPGAPGPAGARGNDG------ATGAAGPPGPTGPAGPPG-FPGAVG 350 Query: 163 AAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAY 222 A A G + G+ G G AGP N G P + + P + Sbjct: 351 AKGEAGPQGPRGSEGPQGVRG--EPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408 Query: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAA 282 P A S P+G PG G G+ P + S + + G G GP+ Sbjct: 409 PGFPGARGPSGPQG--PG-GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465 Query: 283 GG-----GTPQPTATPTLNQLLTSPSSARG---YQGYPGGDYSGGPQDGGAGKGPADMAS 334 G G P PT P P RG +G+PG D GP+ +G A Sbjct: 466 EGKRGARGEPGPTGLP-------GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518 Query: 335 QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQP 394 A A GA+ + +P SPG G G P P Q G+ P Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTG-SPGSPGPDGKTGPP--------GPAGQDGRPGPPG 569 Query: 395 YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPY 454 G + G P GP+ G PG+ P A+G + Sbjct: 570 PPGARGQAGVMGFP-GPKGAAGEPGKAGERGVPG---------PPGAVGPAGKDGEAGAQ 619 Query: 455 GQQGPSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513 G GP+G G++G+ Q P P +Q P P ++ Sbjct: 620 GPPGPAGPAGERGE------------------------QGPAGSPGFQGLPGPAGPPGEA 655 Query: 514 SQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQ--------QP 565 +P P AP PS + P + P P + Sbjct: 656 GKPGEQGVPGD-----LGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710 Query: 566 QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKG-- 623 AP Q A P Q ++ A P P+ D+ A +P +G Sbjct: 711 DAGAPGAPGSQGA-PGLQGMPGERGAAG---LPGPKGDRGDAGPKGADGSPGKDGVRGLT 766 Query: 624 ----------GQEDMNLSLQSRPSSLPDLSGSIDDL----PMGTEGALSPGVSTSGISSS 669 D S S P+ G+ D P G G P G Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP----PGADGQ 822 Query: 670 QGEQSNPAQSPFSPHTSPHLPGIRGPSPSP-----VGSP-ASVAQSRSGPLSPAAVPG-- 721 G + P + P PG GP+ P VG+P A A+ +GP PG Sbjct: 823 PGAKGEPGDAGAKGDAGP--PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880 Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI 781 ++ P PSG + P ++ G R P + +PG P P Sbjct: 881 GRVGPPGPSGNAG----PPGPPGPAGKEGGKGPRGETGP---AGRPGEVGPPGPPGPAG- 932 Query: 782 HTGMGSYQQNSMGSYGPQG--GQYGPQG--------GYPRQPNYNALPNANYPSAGMAGG 831 ++ S G+ GP G G GPQG G P Q P PS G G Sbjct: 933 -------EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS-GEPGK 984 Query: 832 INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGS---------- 881 P GA G+ G PG P G PPG R P P + GS Sbjct: 985 QGPSGASGE-RGPPG--PMG--PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039 Query: 882 GMCPPPG--------------GMNRKTQETAVAMHVA-ANSIQNRPPGYPNMNQGGMMGT 926 G PPG G + ET A + R P P +G T Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET 1099 Query: 927 GPPYGQGINSMAGMINPQGPPYSMG--GTMANNSAGMAASP 965 G +GI G QGPP G G + A A P Sbjct: 1100 GEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGP 1140 Score = 102 bits (254), Expect = 4e-21 Identities = 239/1046 (22%), Positives = 326/1046 (31%), Gaps = 234/1046 (22%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66 P G P PP P L GG A + E K+ G GP +GP Sbjct: 138 PGLPGPPGPPGPPGPPGL-----------GGNFAPQLSYGYDE-KSTGGISVPGP-MGPS 184 Query: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGG 126 P G G G G GP EP ++G GPR PPG G Sbjct: 185 GPRGLP--------GPPGAPGPQGFQGPPGEPGEPGASGPMGPRG--------PPGPPGK 228 Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186 DG P G+P R P G + PG A L Sbjct: 229 NGDDGEAGKP--------------GRPGERGPPG-----------PQGARGLPGTAGLP- 262 Query: 187 GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG-SGAAA 245 G G ++G D G PA P G+PG +GA Sbjct: 263 -GMKGHRGFSGLDGAKGDAG--------------------PAGPKGEP--GSPGENGAPG 299 Query: 246 AAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA 305 G + P + + A+ GA G GP P PT P+ Sbjct: 300 QMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP-------PGPTG----------PAGP 342 Query: 306 RGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA--QQRSHHAPMS 363 G+ G G GPQ +GP + + A AA A + GA Q + A + Sbjct: 343 PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402 Query: 364 PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG 423 PG +G G P AR PS P Q G P GP+ G PG P Sbjct: 403 PGIAGAPGFPGAR--GPSGP-------------------QGPGGPPGPKGNSGEPGAP-- 439 Query: 424 SQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSP-----H 477 + G + P G QGP G G++G+ + P Sbjct: 440 ----------------GSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483 Query: 478 PQQQQPPYSQQPPSQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPS 536 P ++ P S+ P A P + P P P + +P + A P Sbjct: 484 PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE-------AGLPG 536 Query: 537 QQSTTQQHPQSQPPYSQPQAQSPY-QQQQPQQPAPSTLSQQA---AYPQPQSQQSQQTAY 592 + T P S P + P Q +P P P QA +P P+ + Sbjct: 537 AKGLTGS-PGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 593 SQQRFPPPQEL-----SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID 647 ++ P P G+Q P+ + + G++ S + LP +G Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ--GLPGPAGPPG 653 Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVG-SPASV 706 + E + + G S ++GE+ P + G++GP P P G A+ Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGERGFPGER-----------GVQGP-PGPAGPRGANG 701 Query: 707 AQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQ 766 A G A PG P Q M + + +G R P+ + Sbjct: 702 APGNDGAKGDAGAPGAPGSQGAPGLQG---MPGERGAAGLPGPKG--DRGDAGPKGADGS 756 Query: 767 PG--------SALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--------GQYGPQG--G 808 PG + P P+G G + G GP G G+ GP G G Sbjct: 757 PGKDGVRGLTGPIGPPGPAGAPGDKG----ESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812 Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTL--PPGRMSHASMG 864 + P + P A AG G P G G G PG P G + P + + S G Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA-GPPG--PIGNVGAPGAKGARGSAG 869 Query: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM 924 P P G P P G N+ PPG P +GG Sbjct: 870 ----PPGATGFPGAAGRVGPPGPSG----------------NAGPPGPPG-PAGKEGGKG 908 Query: 925 GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG---DVKLTPATKM 981 G G G P GP G A+ AG +P G+ V P + Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968 Query: 982 NNKADGTPKTESKSKKSSSSTTTNEK 1007 G P + K S + E+ Sbjct: 969 ERGFPGLPGPSGEPGKQGPSGASGER 994 Score = 99.8 bits (247), Expect = 3e-20 Identities = 230/982 (23%), Positives = 297/982 (30%), Gaps = 172/982 (17%) Query: 31 QREEAGGEAAAAAAAERGEMKAAAGQESEGPA--------------VGPPQPLGKELQDG 76 +R G A A G AA GPA GP P G E G Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368 Query: 77 AESNGG--GGGGGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV 132 G G G AG G PGA+ P K +NG G A PG G G Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF-----PGARGPSGPQGP 423 Query: 133 GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192 G PP + P G P + + V G Q PG A + G Sbjct: 424 GGPPGPKGNSGEP-----GAPGSKGDTGAKGEPGPV-----GVQGPPGPAGEEGKRGARG 473 Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP 252 EP GP G P P +P A ++ P+G G+ AG K Sbjct: 474 EP--GPT------GLPGPPGERGGPGSRGFPG---ADGVAGPKGPAGERGSPGPAGPKGS 522 Query: 253 PSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYP 312 P + + A+ G+ G GP G P A P ARG G Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG--PPGPAGQDGRPGPPGPPGARGQAGV- 579 Query: 313 GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP----GSSG 368 G P GA P + A A G A + P P G G Sbjct: 580 ----MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635 Query: 369 GGGQP-LARTPQPSSPMDQMGKMR----PQPYGGTNPYSQQ-----------QGPP--SG 410 G P P P+ P + GK P G P + QGPP +G Sbjct: 636 PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695 Query: 411 PQQGHGYPGQP--YGSQTPQRYPMTMQGRAQSAMGGLSYTQQIP-PYGQQGPSGYGQQGQ 467 P+ +G PG G P + M G +P P G +G +G Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755 Query: 468 TPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP---QSQPPQLQSSQPPYSQQPSQ 524 +P + PP P + PS P + P PP + Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815 Query: 525 PPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584 PP + + PP P P P + + A + + Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPP-------GPAGPAGPPGPIGNVGAPGAKGARGSA 868 Query: 585 QQSQQTAY--SQQRFPPPQELSQDS-------FGSQASSAPSMTSSKGGQEDMNLSLQSR 635 T + + R PP G + P + G+ + Sbjct: 869 GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPG-EVGPPGP 927 Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGP 695 P + D P G G P GI+ +G P Q PG+ GP Sbjct: 928 PGPAGEKGSPGADGPAGAPGTPGP----QGIAGQRGVVGLPGQ-----RGERGFPGLPGP 978 Query: 696 SPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS--GQSDSIMHPSMNQSSIAQ-DRGY 752 S P S A GP P PG PP G + P + S A+ DRG Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG- 1037 Query: 753 MQRNPQMPQYSSPQPGSA--LSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGG 808 + P P + PG+ + P SG + TG G GP G G GPQG Sbjct: 1038 -ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAG----PAGPVGPVGARGPAGPQG- 1091 Query: 809 YPRQPNYNALPNANYPSAGMAG--GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866 P + G G GI + G PG PPG S G + Sbjct: 1092 ----------PRGDKGETGEQGDRGIKGHRGFSGLQGPPG-------PPG-----SPGEQ 1129 Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926 GP+ A+ P +G PPG PG +N G+ G Sbjct: 1130 --GPSGASGP----AGPRGPPGSAGA--------------------PGKDGLN--GLPGP 1161 Query: 927 -GPPYGQGINSMAGMINPQGPP 947 GPP +G AG + P GPP Sbjct: 1162 IGPPGPRGRTGDAGPVGPPGPP 1183 Score = 98.6 bits (244), Expect = 6e-20 Identities = 196/822 (23%), Positives = 257/822 (31%), Gaps = 146/822 (17%) Query: 17 PPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDG 76 PP P E + ++ R E G ERG + ++G A GP P G+ G Sbjct: 459 PPGPAGE--EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA-GPKGPAGERGSPG 515 Query: 77 AESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134 G G G G G PGA+ L S G+ GP + T PPG G G Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAK-GLTGSPGSPGP-----DGKTGPPGPAGQDGRPGPPG 569 Query: 135 PPHSAAAA----LPPPAYGFGQPYGRS-----PSAVAAAAAAVFHQQHGGQQSPGLAALQ 185 PP + A P P G+P G++ P A A + G Q PG A Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEP-GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628 Query: 186 S-------GGGGGLEPYAGPQQNSHDHGFPNHQ----------------YNSYYPNRSAY 222 G G + GP + G P Q + R Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688 Query: 223 PPPAPAYALSSPRG--GTPGS-------GAAAAAGSKPPPSSSASASSSSSSFAQQRFGA 273 PP PA PRG G PG+ GA A GS+ P ++ G Sbjct: 689 GPPGPA----GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744 Query: 274 MGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDG----GAGKGP 329 G GP A G + LT P G G PG GP GA P Sbjct: 745 RGDAGPKGADGSPGKDGVRG-----LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP 799 Query: 330 ADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQ-PSSPMDQMG 388 D G A A Q + P G+ G G P P P P+ +G Sbjct: 800 GDRGEP--GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVG 857 Query: 389 KMRPQ-------PYGGTN-PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA-- 438 + P G T P + + P GP G PG P P +G Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG--------PAGKEGGKGP 909 Query: 439 QSAMGGLSYTQQIPPYGQQGPSGY----------------------GQQGQTPYYNQQSP 476 + G ++ P G GP+G GQ+G Q+ Sbjct: 910 RGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGE 969 Query: 477 HPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP--Y 534 P S +P Q P + P P + P S + P + SP Sbjct: 970 RGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGS 1029 Query: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594 P + + + PP P A P P P P +S +T + Sbjct: 1030 PGAKGDRGETGPAGPP-GAPGA--------PGAPGP-------VGPAGKSGDRGETGPAG 1073 Query: 595 QRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654 P ++ G Q G Q D + S L G P G+ Sbjct: 1074 PAGPVGPVGARGPAGPQGPRGDK--GETGEQGDRGIKGHRGFSGLQGPPG-----PPGSP 1126 Query: 655 GALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSR-SGP 713 G P SG S G + P + +P G+ G P P+G P ++ +GP Sbjct: 1127 GEQGP----SGASGPAGPRGPPGSAG-----APGKDGLNG-LPGPIGPPGPRGRTGDAGP 1176 Query: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQR 755 + P PG PP PPS D P Q A D G R Sbjct: 1177 VGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEK-AHDGGRYYR 1217 Score = 82.8 bits (203), Expect = 4e-15 Identities = 127/505 (25%), Positives = 158/505 (31%), Gaps = 90/505 (17%) Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGK-ELQ 74 PP P + K E AG A A +RGE GP QP K E Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830 Query: 75 DGAESNGGGGGGGAGSGGGPG-----AEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129 D G G AG G PG P K + G+AGP P G G++ Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP----------PGATGFPGAA 880 Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189 VG P S A P P G+ G+ P G+ P +G Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKGPR---------------GETGP------AGRP 919 Query: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAA 247 G + P GP + + G P + P P P ++ RG G PG Sbjct: 920 GEVGP-PGPPGPAGEKGSPGADGPAGAPG-----TPGP-QGIAGQRGVVGLPGQRGERGF 972 Query: 248 GSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSA 305 P PS G G GPS A G G P P P L P Sbjct: 973 PGLPGPS-----------------GEPGKQGPSGASGERGPPGPMGPPG----LAGPPGE 1011 Query: 306 RGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAA----AASGGAQQRSHHAP 361 G +G PG + S G KG A A A +G + R P Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGP 1071 Query: 362 MSPGSSGG--GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP-QQGHGYP 418 P G G + A P + G+ + G +S QGPP P G P Sbjct: 1072 AGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGP 1131 Query: 419 GQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSPH 477 G P+ P + + + GL P G GP G G G P Sbjct: 1132 SGASGPAGPRGPPGSAGAPGKDGLNGLP-----GPIGPPGPRGRTGDAGPVGPPGPPGP- 1185 Query: 478 PQQQQPP-------YSQQPPSQTPH 495 P PP + QPP + H Sbjct: 1186 PGPPGPPSAGFDFSFLPQPPQEKAH 1210 Score = 62.0 bits (149), Expect = 6e-09 Identities = 113/447 (25%), Positives = 146/447 (32%), Gaps = 111/447 (24%) Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGP 61 A +V P S PP PP K+ + R E G AG+ E Sbjct: 880 AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG----------------PAGRPGEVG 923 Query: 62 AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121 GPP P G++ GA+ G AG+ G PG + G AG R + P Sbjct: 924 PPGPPGPAGEKGSPGAD-------GPAGAPGTPGPQ-------GIAGQR-----GVVGLP 964 Query: 122 GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL 181 G G G LP P+ G+P + PS + G++ P Sbjct: 965 GQRGERGFPG-----------LPGPS---GEPGKQGPSGAS------------GERGP-- 996 Query: 182 AALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGS 241 G G AGP S G P + + P R P + P G Sbjct: 997 -----PGPMGPPGLAGPPGESGREGAPGAEGS---PGRDGSPGAKGDRGETGPAGPPGAP 1048 Query: 242 GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTS 301 GA A G P S + + G +G GP AG P+ T Q Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP--AGPQGPRGDKGETGEQ---G 1103 Query: 302 PSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAP 361 +G++G+ G GP +GP + ASG A R Sbjct: 1104 DRGIKGHRGFSGLQGPPGPPGSPGEQGP-----------------SGASGPAGPRG---- 1142 Query: 362 MSPGSSGGGGQP-LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420 PGS+G G+ L P P P P P G T + GPP GP G PG Sbjct: 1143 -PPGSAGAPGKDGLNGLPGPIGP--------PGPRGRTGD-AGPVGPP-GPPGPPGPPGP 1191 Query: 421 PYGSQTPQRYPMTMQGRAQSAMGGLSY 447 P P Q +A GG Y Sbjct: 1192 PSAGFDFSFLPQPPQEKAHD--GGRYY 1216 Score = 48.1 bits (113), Expect = 1e-04 Identities = 125/586 (21%), Positives = 168/586 (28%), Gaps = 77/586 (13%) Query: 1108 ERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAS 1167 ERG PP A PP PAG +G Q P + G PP A Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656 Query: 1168 TPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYE 1227 P Q P +G + F + PG + G + Sbjct: 657 KPGEQGVP-------GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK 709 Query: 1228 PNKDPYGS--MRKAPG-----SDPFMSSGQGPNGGMGD--PYSRAAGPGLGNV-----AM 1273 + G+ + APG + + GP G GD P PG V + Sbjct: 710 GDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI 769 Query: 1274 GPRQHYPYGGPYDRVRTEPGIGPEG-NMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQ 1332 GP P G P D+ + P GP G + GAP P P ++ PP Q Sbjct: 770 GPPG--PAGAPGDKGESGPS-GPAGPTGARGAPGDRGEPGPPGPAGFAG---PPGADGQP 823 Query: 1333 QQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPP-AKRHEGEMYSV 1391 + + P G P+ + G+ GPP A G V Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883 Query: 1392 PYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERR----- 1446 G P PP P PA ++ P + + G P + Sbjct: 884 ----GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA 939 Query: 1447 --PAGGPQNQFPFQF-GRDRVSAPPGTNAQQNMP--PQMMG-----GPIQASAEVAQQGT 1496 PAG P P G+ V PG ++ P P G GP AS E G Sbjct: 940 DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP 999 Query: 1497 MWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQP--- 1553 M + R+ A P G A G+ + G P Sbjct: 1000 MGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGP 1059 Query: 1554 -----------PYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSS--------------- 1587 P GP+ PV P+ P+ Q P + + Sbjct: 1060 AGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGP 1119 Query: 1588 PAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1633 P P P E S + P G P + P P+ PP Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPP 1165 Score = 37.0 bits (84), Expect = 0.22 Identities = 85/359 (23%), Positives = 111/359 (30%), Gaps = 73/359 (20%) Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFN 1192 P G+ GPQ P+ + G+ PP PA A N Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG------------------AAGPAGN 387 Query: 1193 DGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252 G+D PG + + + G + + P G + PG P GP Sbjct: 388 PGADG----------QPGAKGANGAPGIAGAPGFPGARGPSGP--QGPGGPP------GP 429 Query: 1253 NGGMGDPYSRAAGPGLGNVAMGPRQHYPYG-----GPYDR-----VRTEPG----IGPEG 1298 G G+P PG + P G GP R EPG GP G Sbjct: 430 KGNSGEP----GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPG 485 Query: 1299 NM----STGAPQPNLM--PSNPDSGMYSPSRYPPQQQQQQQQRHDSYG--NQFSTQGTPS 1350 S G P + + P P SP P+ + R G G+P Sbjct: 486 ERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP- 544 Query: 1351 GSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQP 1410 GSP P +T Q+ RP G GPP R + + P G + P Sbjct: 545 GSPGPDGKTGPPGPAGQD-GRP--GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601 Query: 1411 QPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPG 1469 P A + G A PA E+ PAG P Q G + PPG Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERG--EQGPAGSPGFQ-----GLPGPAGPPG 653 Score = 34.7 bits (78), Expect = 1.1 Identities = 54/228 (23%), Positives = 78/228 (34%), Gaps = 32/228 (14%) Query: 1110 GEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTP 1169 G + P + +K + + P P G+ G P + + G+ P PA Sbjct: 1019 GAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG-- 1076 Query: 1170 HSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPN 1229 P+ + G Q D ++ Q + + G+ S + G P Sbjct: 1077 -----PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGF------SGLQG-----PP 1120 Query: 1230 KDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR 1289 P + P S GP G G P S A PG + P P G P R R Sbjct: 1121 GPPGSPGEQGP------SGASGPAGPRGPPGS-AGAPGKDGLNGLPG---PIGPPGPRGR 1170 Query: 1290 TEPGIGPEGNMSTGAPQPNLMPSNPDSGM-YSPSRYPPQQQQQQQQRH 1336 T GP G G P P P P +G +S PPQ++ R+ Sbjct: 1171 TGDA-GPVG--PPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRY 1215 Score = 33.1 bits (74), Expect = 3.2 Identities = 89/409 (21%), Positives = 119/409 (29%), Gaps = 61/409 (14%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPP-------------LPG 1178 PP G GP P+ + GD P + PP LPG Sbjct: 204 PPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPG 263 Query: 1179 MSRSNSV-GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMR 1237 M G+ A D + + G M + G P G Sbjct: 264 MKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG--- 320 Query: 1238 KAPGSDPFMSSG--QGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPG-- 1293 A G+D + GP G G P A G GP+ GP VR EPG Sbjct: 321 -ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA--GPQGPRGSEGP-QGVRGEPGPP 376 Query: 1294 -----IGPEGNM----------STGAP----QPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334 GP GN + GAP P + SG P P + + Sbjct: 377 GPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP 436 Query: 1335 RHDSYGNQFSTQGTP-----SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMY 1389 +G P G P P+ + ++ + G GPP +R Sbjct: 437 GAPGSKGDTGAKGEPGPVGVQGPPGPAGEE---GKRGARGEPGPTGLPGPPGERGGPGSR 493 Query: 1390 SVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAG 1449 P + G P+ P PA P + G A A T + Sbjct: 494 GFPGADGVAGPKGPAGERGSPGPAG------PKGSPGEAGRPGEAGLPGAKGLTGSPGSP 547 Query: 1450 GPQNQF--PFQFGRDRVSAPPGTNAQQNMPPQM-MGGPIQASAEVAQQG 1495 GP + P G+D PPG + M GP A+ E + G Sbjct: 548 GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 112 bits (279), Expect = 5e-24 Identities = 244/1004 (24%), Positives = 314/1004 (31%), Gaps = 172/1004 (17%) Query: 7 PAAASSLGNP----PPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA 62 P G+P PP PP + +R + G E G + GP Sbjct: 639 PGEKGHRGDPGPSGPPGPPGD-----DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPP 693 Query: 63 VGPPQPLGKELQDGAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEP 120 GPP G + Q G + N G G G G G PGA+ L G GP P L +P Sbjct: 694 -GPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQ-GLPGPQGAIGP-PGEKGPLGKP 750 Query: 121 PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 G G+ G P H P G G P + P PG Sbjct: 751 GLPGMPGAD---GPPGHPGKEGPPGEKGGQGPPGPQGPIGY-----------------PG 790 Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYN-SYYPNRSAYPPPAPAYALSSPRGGTP 239 ++ G G+ G + + GFP + + +R PP P P G Sbjct: 791 PRGVK--GADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPR-GEDGPEGPKG 847 Query: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG----GGPSAAG--GGTPQPTATP 293 G G PP R G G G P A G GG P Sbjct: 848 RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPG 907 Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA 353 Q P+ RG +G G GP+ G GPA + G Sbjct: 908 PRGQ--RGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGP 965 Query: 354 QQRSHHAPMSPGSSGGGGQPLARTPQ----PSSPMDQMGKMRPQ-PYGGTNPYSQQQGP- 407 P PG G G P R + P G + PQ P G T P ++ P Sbjct: 966 -------PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018 Query: 408 PSGPQQGHGYPGQPYGSQTP-QRYPMTMQGR-AQSAMGGLSYTQQIP-PYGQQGPSGY-- 462 P GP G PG T P + G+ + G + +P P G G G Sbjct: 1019 PPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG 1078 Query: 463 --GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ 520 G G ++ P +P Q P + P + PQ + + Q Sbjct: 1079 PPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGL-Q 1137 Query: 521 QPSQPPHQQSPAPYPSQQSTTQQ--HPQSQPPYSQPQAQSPYQQQQPQ----QPAPSTLS 574 P P P P + + P + Q P PQ QP PS Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD 1197 Query: 575 QQAAYPQPQSQQS---QQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631 + P P+ QQ Q+ + FP P G Q P KG D+ Sbjct: 1198 GE---PGPRGQQGLFGQKGDEGPRGFPGPP----GPVGLQGLPGPP--GEKGETGDVG-- 1246 Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS--SQGEQSNPAQSPFSPHTSPHL 689 Q P P G P G GA P GI + + GE+ P ++ P L Sbjct: 1247 -QMGPPGPPGPRG-----PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAG-----EPGL 1295 Query: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRP--PSGQSDSIMHPS------- 740 PG GP P P G + SGP A PG + PP P G + P Sbjct: 1296 PGEGGP-PGPKGERGE--KGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGE 1352 Query: 741 ---MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQ-------- 789 Q D+G + + Q SP P P P G + G + Sbjct: 1353 PGPAGQDGPPGDKG---DDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGA 1409 Query: 790 QNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQP 845 + G GP G G GPQG P +P + L P G+ G P G G M G P Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGA-PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPM-GPP 1467 Query: 846 GIPPY--GTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHV 903 G+P + P G H + G+ PPG K Sbjct: 1468 GLPGLKGDSGPKGEKGHPGL-----------------IGLIGPPGEQGEKGDR------- 1503 Query: 904 AANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPP 947 G P G +GP QGI +G I P GPP Sbjct: 1504 ----------GLP----GPQGSSGPKGEQGITGPSGPIGPPGPP 1533 Score = 105 bits (263), Expect = 4e-22 Identities = 257/1020 (25%), Positives = 329/1020 (32%), Gaps = 154/1020 (15%) Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG---------GGGG 86 G E A G M GQ + GPP G DG G GGGG Sbjct: 472 GPEGPAGLPGPPGTM-GPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGG 530 Query: 87 GAGSGGG------PGAEPDLKNSN----GNAGPRPALNN-NLTEPPGGGG-GGSSDGVGA 134 AGS G A+ L+ + G AGP PPG GG G VG Sbjct: 531 DAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGP 590 Query: 135 PPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ--HGGQQSPGLAALQSGGGGGL 192 P PA G+P GR A + A + Q G + GLA L G Sbjct: 591 QGPRGVQGPPGPA---GKP-GRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRG 646 Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAAGSK 250 +P GP G + + P L P+G G PG + Sbjct: 647 DP--GPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQ 704 Query: 251 PPPSSSASASSSSSSFAQQ-RFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSARG 307 P P + QQ GA G GP A G G P P L + A G Sbjct: 705 PGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGM----PGADG 760 Query: 308 YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSS 367 G+PG + G + G GP A G + PG Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF-PGFK 819 Query: 368 GGGGQPLARTP-QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPS-----GPQQGHGYPGQ- 420 G G R P P + G P+ GG N GPP G GYPG+ Sbjct: 820 GDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ 879 Query: 421 -PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSPHP 478 P GS +P A GG + P GQ+GP+G G++G + P Sbjct: 880 GPKGSIGFPGFP-----GANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKG 934 Query: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ 538 + P + P+ Q P P + P PP + +P Q+ Sbjct: 935 NSGGDGPAGPPGERGPNGP----QGPTGFPGP---------KGPPGPPGKDGLPGHPGQR 981 Query: 539 STTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ-QAAYPQPQSQQSQQTAYSQQRF 597 T ++ PP P PQ P T + +P P +Q Sbjct: 982 GETGFQGKTGPP-------GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL------ 1028 Query: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGA 656 P ++ G++ P+ K G L+ P L G + L + G EG Sbjct: 1029 --PGLAGKE--GTKGDPGPAGLPGKDGPP----GLRGFPGDR-GLPGPVGALGLKGNEGP 1079 Query: 657 LSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS------- 709 P G + S GE+ PA + P P PG +GP P P G + + Sbjct: 1080 PGP----PGPAGSPGERG-PAGAA-GPIGIPGRPGPQGP-PGPAGEKGAPGEKGPQGPAG 1132 Query: 710 RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM-QRNPQMPQYSSPQPG 768 R G P +PG P PP D Q D+G P PQ QPG Sbjct: 1133 RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG 1192 Query: 769 SALSPRQPSG-GQIHTGMGSYQQNSMGSYGPQG--------------------GQYGPQG 807 + + +P GQ + G GP G GQ GP G Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG 1252 Query: 808 GY-PRQPNYNALPNANYPSAGMAGGINPMGAGGQMH-----GQPGIPPYGTLPPGRMSHA 861 PR P+ P A+ P G GGI GA G+ G+PG+P G P + Sbjct: 1253 PPGPRGPS--GAPGADGPQ-GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERG 1309 Query: 862 SMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMH-------VAANSIQNRPPG 914 G GP+ A PP G PPG K V + Q+ PPG Sbjct: 1310 EKGES--GPSGAAGPP----GPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPG 1363 Query: 915 YPNMN----QGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMG 969 + Q G G TG P G G P GP G A AG+ P G Sbjct: 1364 DKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG 1423 Score = 101 bits (252), Expect = 7e-21 Identities = 211/897 (23%), Positives = 277/897 (30%), Gaps = 152/897 (16%) Query: 14 GNPPPPPPSELKKAEQQQREEAGG-EAAAAAAAERGE-----MKAAAGQESEGPAVGPPQ 67 G PP P + + + A G E+GE K G + + +GPP Sbjct: 776 GQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835 Query: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGAE-----PDLKNSNGNAGPRPALNNNLTEPPG 122 P G++ +G + GG G G G PG + P L G GP+ ++ P Sbjct: 836 PRGEDGPEGPKGR-GGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK----GSIGFPGF 890 Query: 123 GGGGGSSDGVGAP----PHSAAAALPP-----PAYGFGQPYGRSPSAVAAAAAAVFHQQH 173 G G G G P P P P G+P + S A + Sbjct: 891 PGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950 Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS 233 G Q P G G + GP G P + + + ++ P P Sbjct: 951 NGPQGP-------TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQG 1003 Query: 234 PRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTA 291 P G T G G PP + G G GP+ G G P Sbjct: 1004 PTGETGPMGERGHPGPPGPPGEQGLPGLAGKE------GTKGDPGPAGLPGKDGPPGLRG 1057 Query: 292 TPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG 351 P ++ L P A G +G G GP +GPA A Sbjct: 1058 FPG-DRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPA 1116 Query: 352 GAQ-QRSHHAPMSPGSSGGGGQPLARTPQPSSPM------DQMGKMRPQPYGGTNPYSQQ 404 G + P P G P+ P P+ P+ G++ G+ + Sbjct: 1117 GEKGAPGEKGPQGPAGRDGLQGPVG-LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGE 1175 Query: 405 QGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQG--RAQSAMGGLSYTQQIPPYGQQG-P 459 QGP P+GPQ G PG P P QG + G + P G QG P Sbjct: 1176 QGPPGPTGPQGPIGQPGPSGADGEPG--PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLP 1233 Query: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519 G++G+T Q P S P + P P P + + +P + Sbjct: 1234 GPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVG---EKGEPGEA 1290 Query: 520 QQPSQPPHQQSPAPYPSQQSTTQQHPQSQ--------PPYSQPQAQSPYQQQQPQQPAPS 571 +P P P P + + P PP SP P P P Sbjct: 1291 GEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGP- 1349 Query: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631 P P Q PP + D Q S P T G Sbjct: 1350 -----PGEPGPAGQDG-----------PPGDKGDDGEPGQTGS-PGPTGEPG-------- 1384 Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQS-PFSPHTSPHLP 690 PS P G P G EG G G + P ++ P P +P P Sbjct: 1385 ----PSGPPGKRGPPG--PAGPEGR----QGEKGAKGEAGLEGPPGKTGPIGPQGAPGKP 1434 Query: 691 ---GIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747 G+RG P PVG Q G P PG PP P + DS Sbjct: 1435 GPDGLRG-IPGPVGE-----QGLPGSPGPDGPPGPMGPPGLPGLKGDS------------ 1476 Query: 748 QDRGYMQRNPQMPQYSSPQPG--SALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQY 803 P+ PG + P G + G+ Q GS GP+G G Sbjct: 1477 -----------GPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ----GSSGPKGEQGIT 1521 Query: 804 GPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRM 858 GP G G P P LP P G G P G G+ G PG PP PPG + Sbjct: 1522 GPSGPIGPPGPP---GLPGPPGPK-GAKGSSGPTGPKGEA-GHPG-PPGPPGPPGEV 1572 Score = 81.6 bits (200), Expect = 8e-15 Identities = 231/1029 (22%), Positives = 311/1029 (30%), Gaps = 175/1029 (17%) Query: 8 AAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67 A S+ NP PPP E + EE + S +GP Sbjct: 381 ADTSNSSNPAPPPGEGADDLEGEFTEET------IRNLDENYYDPYYDPTSSPSEIGPGM 434 Query: 68 PLGKELQDGAESNGGGGGGGAGSGG---------------GPGAEPDLKNSNGNAGPRPA 112 P QD GG G G G GP L G GP Sbjct: 435 PAN---QDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQ 491 Query: 113 LNN-NLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSP--SAVAAAAAAVF 169 + + PPG G +DG+ PP LP G G + P SA + A A+ Sbjct: 492 VGDPGERGPPGRPGLPGADGLPGPP-GTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAIL 550 Query: 170 HQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAY 229 Q + P +G G + GP + G P P R PP PA Sbjct: 551 QQARLALRGPAGPMGLTGRPGPV----GPPGSGGLKGEPG-DVGPQGP-RGVQGPPGPA- 603 Query: 230 ALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288 G PG G A + G++ P + F + G G P Sbjct: 604 -------GKPGRRGRAGSDGARGMPGQTGPKGDRG-------FDGLAGLPGEKGHRGDPG 649 Query: 289 PTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAA 348 P+ P G G G D GP+ GP + Sbjct: 650 PSGPP----------GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVT 699 Query: 349 ASGGAQ-QRSHHAPMS-PGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQ 405 G + + P PG G G P A+ P P + G+ P G Sbjct: 700 GMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGAD 759 Query: 406 GPPSGPQQGHGYPGQ-----PYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPS 460 GPP P + G PG+ P G Q P YP + + GL T+ G++G Sbjct: 760 GPPGHPGK-EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTK-----GEKGED 813 Query: 461 GY-GQQGQTPYYNQQS----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ 515 G+ G +G + P P+ + P + P+ P P + Sbjct: 814 GFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGG-PNGDPGPLGPPGEKGKLGVPGL 872 Query: 516 PPYSQQPSQPPHQQSPA-PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ----QPAP 570 P Y + P P + + + P P Q P ++ P+ +P P Sbjct: 873 PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932 Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630 S P ++ FP P+ P K G Sbjct: 933 KGNSGGDGPAGPPGERGPNGPQGPTGFPGPK-------------GPPGPPGKDG------ 973 Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690 L P + P G G + P T G + GE+ +P P P LP Sbjct: 974 -LPGHPGQRGETGFQGKTGPPGPPGVVGPQGPT-GETGPMGERGHPG--PPGPPGEQGLP 1029 Query: 691 GIRGPS-----PSPVGSPASVA----------QSRSGPLSPAAVPGNQMPPRPPS-GQSD 734 G+ G P P G P + GP+ + GN+ PP PP S Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089 Query: 735 SIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMG 794 P+ I + P P PG P+ P+G G+ Q +G Sbjct: 1090 GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEK-GPQGPAG---RDGL----QGPVG 1141 Query: 795 SYGPQG-----GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI 847 GP G G+ G +G G P Q G G P G G + GQPG Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKG-------DKGEQGPPGPTGPQGPI-GQPGP 1193 Query: 848 PPYGTLPPGRMSHASMGNR-PYGPNMANMPP-QVGSGMCPPPGGMNRKTQETAVAMHVAA 905 P R G + GP PP VG P P G +T + Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVG------- 1246 Query: 906 NSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMA---NNSAGMA 962 Q PPG PP +G + G PQGPP +G A G A Sbjct: 1247 ---QMGPPG-------------PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEA 1290 Query: 963 ASPEMMGLG 971 P + G G Sbjct: 1291 GEPGLPGEG 1299 Score = 59.7 bits (143), Expect = 3e-08 Identities = 137/602 (22%), Positives = 194/602 (32%), Gaps = 127/602 (21%) Query: 478 PQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ 537 PQ Q P + + Y + P + P+ +P S++P + + + P Sbjct: 252 PQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELT 311 Query: 538 QSTTQQHPQSQP------------------PYSQPQAQSPYQ-------QQQPQQPAPST 572 + T+ P + P SPY ++ P QP Sbjct: 312 PTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPT--- 368 Query: 573 LSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSL 632 A P S + T+ S PPP E + D G + ++ + D Sbjct: 369 -DPGAGAEIPTS--TADTSNSSNPAPPPGEGADDLEGE--FTEETIRNLDENYYDPYYDP 423 Query: 633 QSRPSSL-PDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPA-----------QSP 680 S PS + P + + D + G G +G++ PA P Sbjct: 424 TSSPSEIGPGMPANQDTIYEG----------IGGPRGEKGQKGEPAIIEPGMLIEGPPGP 473 Query: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPP----------S 730 P P PG GP+ VG P GP +PG P PP Sbjct: 474 EGPAGLPGPPGTMGPT-GQVGDP-----GERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527 Query: 731 GQSDSIMHPSMNQSSIAQDRGYMQ------RNPQMPQYSSPQPGSA-------------- 770 G D+ M + +Q + +Q R P P + +PG Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587 Query: 771 LSPRQPSGGQIHTGMGSY--QQNSMGSYGPQG--GQYGPQG--------GYPRQPNYNAL 818 + P+ P G Q G ++ GS G +G GQ GP+G G P + + Sbjct: 588 VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647 Query: 819 PNANYPSAGMAGGINPMGAGGQM--HGQPGIP-PYGTL-------PPGRMSHASMGNRPY 868 P + P G G G G++ G PG P P G L PPG M +P Sbjct: 648 PGPSGP-PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQP- 705 Query: 869 GPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT-G 927 GP N+ PQ G PP N Q + P G P + GM G G Sbjct: 706 GPK-GNVGPQGEPG--PPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGL--PGMPGADG 760 Query: 928 PPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADG 987 PP G G QGPP G G+ + + GL TK DG Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGL------KGTKGEKGEDG 814 Query: 988 TP 989 P Sbjct: 815 FP 816 Score = 53.1 bits (126), Expect = 3e-06 Identities = 97/426 (22%), Positives = 138/426 (32%), Gaps = 85/426 (19%) Query: 525 PPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584 P QS P P + T Y P + P + ++P PS +AA Sbjct: 249 PDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDP--EDLGKEPTPSKKPVEAA------ 300 Query: 585 QQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG 644 + T ++ P P E A+ P + G +ED+ + G Sbjct: 301 --KETTEVPEELTPTPTE---------AAPMPETSEGAGKEEDVGI-------------G 336 Query: 645 SIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPA 704 D +P SP ++ +GE+ NP Q P+ G+ A Sbjct: 337 DYDYVPSEDYYTPSP---YDDLTYGEGEE-NPDQ------------------PTDPGAGA 374 Query: 705 SVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSS 764 + S A N P PP G+ + + +I + N P Y Sbjct: 375 EIPTS-------TADTSNSSNPAPPPGEGADDLEGEFTEETIRN----LDENYYDPYYDP 423 Query: 765 PQPGSALSPRQPSGGQ-IHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNA 821 S + P P+ I+ G+G GP+G GQ G P Sbjct: 424 TSSPSEIGPGMPANQDTIYEGIG----------GPRGEKGQKGEPAIIEPGMLIEGPPGP 473 Query: 822 NYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPN-MANMPPQVG 880 P AG+ G MG GQ+ G PG PPGR P P M +P + G Sbjct: 474 EGP-AGLPGPPGTMGPTGQV-GDPGERG----PPGRPGLPGADGLPGPPGTMLMLPFRFG 527 Query: 881 SGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGM 940 G G QE+ + + R P P G GPP G+ G Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587 Query: 941 INPQGP 946 + PQGP Sbjct: 588 VGPQGP 593 Score = 52.4 bits (124), Expect = 5e-06 Identities = 174/805 (21%), Positives = 242/805 (30%), Gaps = 152/805 (18%) Query: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGG----------GPSAAGGGTPQ 288 P S A + S P P A F ++ + PS G G Sbjct: 377 PTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPG--M 434 Query: 289 PTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAG-KGPADMASQCWGAAAAAAAAA 347 P T+ + + P +G +G P G +G G +GPA + G Sbjct: 435 PANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP----GPPGTMGPTG 490 Query: 348 AASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407 ++ P PG+ G P P M M P +GG + +GP Sbjct: 491 QVGDPGERGPPGRPGLPGADG--------LPGPPGTM----LMLPFRFGGGGD-AGSKGP 537 Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ 467 Q+ Q+ + ++G A G + T + P G G G +G+ Sbjct: 538 MVSAQESQA-------QAILQQARLALRGPA----GPMGLTGRPGPVGPPGSGGL--KGE 584 Query: 468 TPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH 527 Q P Q P + +P + + P P+ + P + H Sbjct: 585 PGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH 644 Query: 528 QQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS 587 + P P + P+ P +P P L P P Sbjct: 645 RGDPGPSGPPGPPGDDGERGDDGEVGPRGL-------PGEPGPRGLLGPKGPPGPPG--- 694 Query: 588 QQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID 647 PP D KG N+ Q P Sbjct: 695 -----------PPGVTGMDG----------QPGPKG-----NVGPQGEPG---------- 718 Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQS-PFSPHTSPHLPGIRGPS--PSPVGSPA 704 P G +G +PG G+ QG P + P P +PG GP P G P Sbjct: 719 --PPGQQG--NPGAQ--GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPG 772 Query: 705 SVA-QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD-----RGYMQRNPQ 758 Q GP P PG PR G +D I + +D +G M Sbjct: 773 EKGGQGPPGPQGPIGYPG----PRGVKG-ADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 827 Query: 759 MPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG--GYP-RQP 813 + P P P P G G G GP G G+ G G GYP RQ Sbjct: 828 RGEIGPPGPRGEDGPEGPKGRGGPNG-------DPGPLGPPGEKGKLGVPGLPGYPGRQG 880 Query: 814 NYNALPNANYPSA-------GMAGGINPMGAGGQMHGQPGIPPYG-TLPPGRMSHASMGN 865 ++ +P A G G P G G + P G T PG ++ G+ Sbjct: 881 PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSG-GD 939 Query: 866 RPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-----QNRPPGYPNM 918 P GP P PQ +G P P G + + H + PPG P + Sbjct: 940 GPAGPPGERGPNGPQGPTGF-PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998 Query: 919 -------NQGGMMGT-------GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAAS 964 + G MG GPP QG+ +AG +G P G + G+ Sbjct: 999 VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF 1058 Query: 965 PEMMGLGDVKLTPATKMNNKADGTP 989 P GL K N G P Sbjct: 1059 PGDRGLPGPVGALGLKGNEGPPGPP 1083 Score = 47.4 bits (111), Expect = 2e-04 Identities = 107/475 (22%), Positives = 143/475 (30%), Gaps = 85/475 (17%) Query: 1106 KIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTP 1165 K E+GED P K + +I PP P G GP+ P+ + G L P P Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGE---DGPEGPKGRGGPNGDPGPLGP--P 861 Query: 1166 ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTP-NPGYQPSMNTSDMMGRM 1224 +P LPG F + +K TP PG + + G Sbjct: 862 GEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGER 921 Query: 1225 SYEPNKDPYGSMRKAPGSDPFMSSGQ-GPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGG 1283 G + G P G+ GPNG P PG P + G Sbjct: 922 GPRGITGKPGPKGNSGGDGPAGPPGERGPNG----PQGPTGFPGPKGPPGPPGKDGLPGH 977 Query: 1284 PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP--DSGMYSPSRYPPQQQQQQQQRHDSYGN 1341 P R T G +G P + P P ++G +P +Q Sbjct: 978 PGQRGET----GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG 1033 Query: 1342 QFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQ 1401 + T+G P + P G GPP R +P G + Sbjct: 1034 KEGTKGDPGPAGLP-------------------GKDGPPGLRGFPGDRGLPGPVGALGLK 1074 Query: 1402 QQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGR 1461 + PP P PA SP G PA A P G P GR Sbjct: 1075 GNEGPPGPPGPAG-------SP--------GERGPAGAAG-----PIGIP--------GR 1106 Query: 1462 DRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGP 1521 PPG ++ P + GP + QG + P GP Sbjct: 1107 PGPQGPPGPAGEKGAPGEK--GPQGPAGRDGLQGPVGL----------------PGPAGP 1148 Query: 1522 AYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPP 1576 G D +GS G + PP GP+ P P+ +P PS P Sbjct: 1149 V--GPPGEDGDKGEIGEPGQKGSKGDKGEQGPP-GPTGPQGPIGQPGPSGADGEP 1200 Score = 35.8 bits (81), Expect = 0.50 Identities = 122/549 (22%), Positives = 163/549 (29%), Gaps = 146/549 (26%) Query: 1106 KIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTP 1165 K ++GE PP Q I P P+G+ GP+ Q + G P P Sbjct: 1170 KGDKGEQGPPG------PTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGP 1223 Query: 1166 ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS 1225 PG VG+Q + PG + MG Sbjct: 1224 -----------PG-----PVGLQ---------------GLPGPPGEKGETGDVGQMGPPG 1252 Query: 1226 YEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDP--YSRAAGPGLGNVAMGPRQHYPYGG 1283 + P G APG+D QGP GG+G+P PG P + P G Sbjct: 1253 PPGPRGPSG----APGAD----GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGP-PG 1303 Query: 1284 PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP-DSGMYSPSRYPPQQQQQQQQRHDSYGNQ 1342 P + GP G + G P P P + G P +P Sbjct: 1304 PKGERGEKGESGPSG--AAGPPGPKGPPGDDGPKGSPGPVGFPGDP-------------- 1347 Query: 1343 FSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPA-KRHEGEMYSVPYSTGQGQPQ 1401 P G P P+ G GPP K +GE P TG P Sbjct: 1348 -----GPPGEPGPA------------------GQDGPPGDKGDDGE----PGQTGSPGPT 1380 Query: 1402 QQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGR 1461 + P P A P +Q + G A + GPQ P + G Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQ---GEKGAKGEAGLEGPPGKTGPIGPQGA-PGKPGP 1436 Query: 1462 DRVSAPPGTNAQQNMP----PQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSA 1517 D + PG +Q +P P GP+ +G S Sbjct: 1437 DGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKG-------------------DSG 1477 Query: 1518 PQGPAYHG-----VNRTDEMLHTDQRA--NHEGSWPSHGTRQPPYGPSAPVPPMTRPPPS 1570 P+G H + E R +GS G Q GPS P+ P P P Sbjct: 1478 PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKG-EQGITGPSGPIGP---PGPP 1533 Query: 1571 NYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV 1630 PP P+ + + P+ P +G P P I P P+ Sbjct: 1534 GLPGPPG--------------PKGAKGSSGPT-GPKGEAGHPGPPGPPGPPGEVIQPLPI 1578 Query: 1631 QPPMIRRDI 1639 Q RR+I Sbjct: 1579 QASRTRRNI 1587 Score = 35.4 bits (80), Expect = 0.65 Identities = 127/577 (22%), Positives = 172/577 (29%), Gaps = 89/577 (15%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ-IPPLPGMSRSNSVGIQDA 1190 PP P G + GP + + + G+ PP P + +P PG + + Sbjct: 470 PPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPG----TMLMLPFR 525 Query: 1191 FNDGSDSTFQKRNSMTPNPGYQPSMNTSDM-MGRMSYEPNKDPYGSMRK-----APGS-- 1242 F G D+ S P Q S + + R++ P G + PGS Sbjct: 526 FGGGGDA-----GSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGG 580 Query: 1243 ---DPFMSSGQGPNGGMGDP--------YSRAAGPGLGNV--AMGPRQHYPYGG----PY 1285 +P QGP G G P RA G + GP+ + G P Sbjct: 581 LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640 Query: 1286 DR-VRTEPG-IGPEG-------NMSTGAPQPNLMPSNP-DSGMYSPSRYPPQQQQQQQQR 1335 ++ R +PG GP G G P +P P G+ P P Sbjct: 641 EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTG 700 Query: 1336 HDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYST 1395 D G P G P P Q Q P G GPP ++ +P Sbjct: 701 MDGQPGPKGNVG-PQGEPGPPGQ--QGNPGAQGLPGP-QGAIGPPGEKGPLGKPGLPGMP 756 Query: 1396 GQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQ- 1454 G P P + P + P PQ + G P A R G + + Sbjct: 757 GADGPPGH--PGKEGPPGEKGGQGPPGPQGPI----GYPGPRGVKGADGIRGLKGTKGEK 810 Query: 1455 ----FPFQFGRDRVS------APPGTNAQQNMP-PQMMGGPIQASAEVAQQGTMWQGRND 1503 FP G + PPG + P+ GGP + G + Sbjct: 811 GEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVP 870 Query: 1504 MTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPP 1563 Y RQ + P + G N T + G G P G P Sbjct: 871 GLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTG----PRGERGPRGI 926 Query: 1564 MTRPPPSNYQ-------PPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFL-HSGMKMQ- 1614 +P P PP + PQ P P P P K H G + + Sbjct: 927 TGKPGPKGNSGGDGPAGPPGERGPNGPQ--GPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984 Query: 1615 ----KAGPPVPASHI---APAPVQPPMIRRDITFPPG 1644 K GPP P + P PM R PPG Sbjct: 985 GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPG 1021 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 107 bits (268), Expect = 1e-22 Identities = 229/1038 (22%), Positives = 351/1038 (33%), Gaps = 123/1038 (11%) Query: 21 PSELKKAEQQQREEAGGE--AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAE 78 PS ++ + G+ + ++ + RG ++ +GQ S G Q Q Sbjct: 307 PSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTS-----GFGQHESGSGQSSGY 361 Query: 79 SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138 S G G G + S G G+ +S+G G +++ G S G HS Sbjct: 362 SKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSY----GQHESASRHSSGRGQHS 417 Query: 139 AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP 198 + + G+SP H Q G ++ Q G G G +GP Sbjct: 418 SGS-------------GQSPG----------HGQRGSGSGQSPSSGQHGTGFGRSSSSGP 454 Query: 199 --QQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS 256 + + GF +H+ +S + S Y SS G ++ G + Sbjct: 455 YVSGSGYSSGFGHHESSS--EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGER-----Q 507 Query: 257 ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ-PTATPTLNQLLTSPSSARGYQGYPGG- 314 S++ SSSS+ Q G+ G S G G+ Q P+ + ++ + SS+ G GY G Sbjct: 508 GSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGR 567 Query: 315 DYSGGPQDGGAG--KGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQ 372 S GP + G+G G S+ G ++ ++SG + H S G S GQ Sbjct: 568 SSSRGPYESGSGHSSGLGHQESRS-GQSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQ 625 Query: 373 PLARTPQPSS-PMDQMGKMRPQPYG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQ 425 A + Q SS G + YG G +P + G G +G G G Sbjct: 626 HGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS 685 Query: 426 TPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG-----PSGYGQQGQTPYYNQQSPHPQQ 480 + ++ G++ S G S + Q Y Q G SGY + G + +S + Sbjct: 686 SSNGPHGSVSGQS-SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRS----E 740 Query: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540 Q S S H S+Q + P + S H S + S S Sbjct: 741 QHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSC 800 Query: 541 T-----------------QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 + Q S YSQ + S + Q + ST Q ++ Q Sbjct: 801 SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRH--GSTSGQSSSSGQHD 858 Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAP--SMTSSKGGQEDMNLSLQSRPSSLPD 641 S Q ++Y Q + GS + +P S GQ PS Sbjct: 859 SSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQS---------PSYGRH 909 Query: 642 LSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQ--------SPFSPHTSPHLPGIR 693 SGS G G+ S S G SS G+ S Q S + H S R Sbjct: 910 GSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969 Query: 694 GPS-PSPVGSPASVAQSRSGPLSPAA----VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQ 748 S GS +S Q SG G+ P P G+ S S + Sbjct: 970 SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029 Query: 749 DRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGG 808 G+ + + P S S L R+ GQ G Q S + GQ+G G Sbjct: 1030 GSGW--SSSRGPYESGSGHSSGLGHRESRSGQ---SSGYGQHGSSSGHSSTHGQHGSTSG 1084 Query: 809 YPRQPNYNALPNANYPSAGM--AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866 + + S G +G G G Q G P +G G S G Sbjct: 1085 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144 Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY-PNMNQGGMMG 925 G ++ Q GSG+ G + ++ + + S GY + ++ G Sbjct: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1204 Query: 926 TGPPYG--QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNN 983 G +G G +S G + G S G + +G + S G G L ++ Sbjct: 1205 RGERHGSSSGSSSHYGQ-HGSGSRQSSGHGRQGSGSGHSPSRGRHGSG---LGHSSSHGQ 1260 Query: 984 KADGTPKTESKSKKSSSS 1001 G+ ++ S+ S S Sbjct: 1261 HGSGSGRSSSRGPYESRS 1278 Score = 100 bits (250), Expect = 1e-20 Identities = 233/1070 (21%), Positives = 349/1070 (32%), Gaps = 137/1070 (12%) Query: 33 EEAGGEAAAAAAAERGEMKAAAGQ-ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG 91 + G + ++ + G + + E G + G G+ G+ + G G G+GSG Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH-GSGSHQSSGHGRQGSGSG 773 Query: 92 GGP-----GAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS-------DGVGAPPH-- 137 P G+ +S+G G + +++ G G S G G H Sbjct: 774 HSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGS 833 Query: 138 -----------------SAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180 S+++ + G YG+ SA A+ H GQ SPG Sbjct: 834 ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ-SPG 892 Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 Q G G G P G + + ++ S S + + + S G Sbjct: 893 HG--QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSG 950 Query: 241 SGAAAAA---GSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293 SG +++ GS+ SS + S+S SSSS+ Q G+ G G G+ Q Sbjct: 951 SGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ----- 1005 Query: 294 TLNQLLTSPSSARGYQGYPGGDYSG-GPQDGGAG----KGPADMAS----------QCWG 338 SPS +RG G G S GP G+G +GP + S G Sbjct: 1006 -------SPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1058 Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQ-MGKMRPQPYGG 397 ++ ++SG + H S G S GQ A + Q SS G + YG Sbjct: 1059 QSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG- 1116 Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL------------ 445 +QG SG GHG G GS+ Y G +S+ G Sbjct: 1117 ------RQGSGSGQSPGHGQRGS--GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1168 Query: 446 ---SYTQQIPPYGQQGP-----SGYGQQGQTPYYNQQ---------SPHPQQQQPPYSQQ 488 S + Q Y Q G SGYGQ G + + S Q S+Q Sbjct: 1169 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228 Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ---STTQQHP 545 S + + + Q S S PY S+ S QH Sbjct: 1229 SSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1288 Query: 546 QSQ---PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602 YSQ + S + Q Q ST Q + + Q S Q ++Y + Q Sbjct: 1289 SGSGHSSAYSQHGSGSGHFCSQGQHG--STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQS 1346 Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662 G+ + +PS G + Q S S G S Sbjct: 1347 SGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES 1406 Query: 663 TSGISS--SQGEQSNPAQSPFSPHTSPHLPGIRGPSP-SPVGSPASVAQSRSGPLSPAAV 719 +S SS +Q + S + H S RG S GS +S Q SG Sbjct: 1407 SSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGH 1466 Query: 720 ----PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQ 775 G+ P P G+ S S + S G+ + + P S S L R+ Sbjct: 1467 GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWS--SSRGPYESGSSHSSGLGHRE 1524 Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGM--AGGIN 833 GQ G Q S + GQ+G G + + S G +G Sbjct: 1525 SRSGQ---SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1581 Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893 G G Q G P +G G S G G ++ Q GSG+ G + + Sbjct: 1582 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 1641 Query: 894 TQETAVAMHVAANSIQNRPPGY-PNMNQGGMMGTGPPYGQGINSMAGM-INPQGPPYSMG 951 + + + S GY + ++ G G +G S + + G S G Sbjct: 1642 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG 1701 Query: 952 GTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSS 1001 + +G + S G G L ++ G+ ++ S+ S S Sbjct: 1702 HGRQGSGSGQSPSRGRHGSG---LGHSSSHGQHGSGSGRSSSRGPYESRS 1748 Score = 100 bits (248), Expect = 2e-20 Identities = 230/1005 (22%), Positives = 335/1005 (33%), Gaps = 163/1005 (16%) Query: 31 QREEAGGEAAAAAA--------AERGEMKAAAGQES----EGPAVGPPQPLGKELQDGAE 78 Q E G ++A + +G+ + +GQ S EG + G G+ ++ Sbjct: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815 Query: 79 SNG----GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA 134 S+ G G G + S G G+ +S G G +++ G G G S G G Sbjct: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH--GSGSGQSSGFGH 1873 Query: 135 PPHSAAAALPPPAYGFGQPYG--------------RSPSAVAAAAAAVFHQQHGGQQSPG 180 S+ + +G G + R +++ ++ + QHG Sbjct: 1874 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQS 1933 Query: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG-TP 239 L Q G G G P P + H G S+Y P SS RG Sbjct: 1934 LGHGQHGSGSGQSP--SPSRGRHGSGSGQS---------SSYGPYGSGSGWSSSRGPYES 1982 Query: 240 GSGAAAAAGSKPPPSSSAS------ASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293 GSG ++ G + S +S +SS SS Q A G G + +++ Sbjct: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042 Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDG------------GAGKGPADMASQCW---G 338 + +S SS G QG G G Q G G+G G + + Q G Sbjct: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102 Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGT 398 ++ ++SG + S H S G S G GQ +R+ Q S G+ G + Sbjct: 2103 ESSGFGHHESSSGQSSSYSQHGSGS-GHSSGYGQHGSRSGQSSR-----GERHGSSSGSS 2156 Query: 399 NPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG 458 + Y Q G S GHG G G +P R GR S G S +GQ G Sbjct: 2157 SRYGQH-GSGSRQSSGHGRQGSGSG-HSPSR------GRHGSGSGHSS------SHGQHG 2202 Query: 459 PSGYGQQGQTPYYNQQSPHPQQ--QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516 SG G+ Y +S H Q S + + H S Q Q Sbjct: 2203 -SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2261 Query: 517 PYSQQPSQPPHQQSPAPYPSQQSTTQQHPQS------QPPYSQPQAQSPYQQQQPQQPAP 570 + Q+ S S + S S + + Q P + + S + Q + Sbjct: 2262 TFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 2321 Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630 S S + S QS + + +Q GS SS+ S+ GQ Sbjct: 2322 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS---- 2377 Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690 S R S S S G+ +L G SG QSP SP H Sbjct: 2378 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG----------SGQSP-SPSRGRHGS 2426 Query: 691 GI-RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749 G + S SP GS + + SR P SG S + H +S Q Sbjct: 2427 GSGQSSSYSPYGSGSGWSSSRG-------------PYESGSGHSSGLGH---RESRSGQS 2470 Query: 750 RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGY 809 GY Q S+ + S + S GQ G S Q +S G +G Q GY Sbjct: 2471 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ--HGASSGQSSSHGQHGSGSSQ---SSGY 2525 Query: 810 PRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYG 869 RQ G G +P HGQ G G S G G Sbjct: 2526 GRQ--------------GSGSGQSPG------HGQRG--------SGSRQSPSYGRHGSG 2557 Query: 870 PNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY-PNMNQGGMMGTGP 928 ++ Q GSG+ G + ++ + + S GY + ++ G G Sbjct: 2558 SGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE 2617 Query: 929 PYG--QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971 +G G +S G + G S G + +G + S G G Sbjct: 2618 RHGSSSGSSSHYGQ-HGSGSRQSSGHGRQGSGSGQSPSRGRHGSG 2661 Score = 90.1 bits (222), Expect = 2e-17 Identities = 236/1078 (21%), Positives = 357/1078 (33%), Gaps = 147/1078 (13%) Query: 26 KAEQQQREEAGGEAAAAAAA--ERGE-MKAAAGQESEGPAVGP-PQPLGKELQDGAESNG 81 ++ Q R E G +A ++++ + G + + G G G P P + G+ + Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556 Query: 82 GGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAP--PHSA 139 G G GSG P ++ +G++ + + G G GSS G + H + Sbjct: 557 SYGPHGYGSGRSSSRGP-YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615 Query: 140 AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQ 199 + G G+S S H QHG S Q G G G P G Sbjct: 616 TSGQSSSCGQHGATSGQSSS----------HGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665 Query: 200 QNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA------------- 246 + H Q+ S S+ P SS G GSG ++ Sbjct: 666 GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG 725 Query: 247 ---AGSKPPPSSSA----SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP---------- 289 GS+ SS + S+S SSS+ Q G+ G G G+ Sbjct: 726 YRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785 Query: 290 --TATPTLNQLLTSPSSARGYQGYPGGDYSG-GPQDGGAGKGPADMAS------------ 334 +++ + TS SS+ G+ G SG G + G+G+G + S Sbjct: 786 GHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHG 845 Query: 335 QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQP 394 G ++++ ++SG + H S +SG G P G + Sbjct: 846 STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905 Query: 395 YG------GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448 YG G + S + G SG G G+ S Y G S+ SY Sbjct: 906 YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKS---SSGQSSGYTQHGSGSGHSS----SYE 958 Query: 449 QQIPPYGQQ-----------GPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497 Q GQ S YGQ G Q H Q PS+ H Sbjct: 959 QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRHGS 1016 Query: 498 PSYQQQ---PQSQPPQLQSSQPPY---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQ 548 S Q P SS+ PY S S H++S + S Q ++ H + Sbjct: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076 Query: 549 PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608 + QS Q ++ Q +++ Q S SQ + Y +Q Q Sbjct: 1077 GQHGSTSGQSSSCGQH-----GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1131 Query: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG-SIDDLPMGTEGALSPGVSTSGIS 667 GS + +PS G + S S L + SG + G + S S SG S Sbjct: 1132 GSGSRQSPSY-GRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190 Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPR 727 S G+ ++S S H G S S G S ++ SG + G+ P R Sbjct: 1191 SGYGQHG--SRSGQSSRGERH--GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS-PSR 1245 Query: 728 PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG- 786 G S + + Q + SS P + S GQ +G G Sbjct: 1246 GRHG------------SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293 Query: 787 --SYQQNSMGS-YGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843 +Y Q+ GS + GQ+G G + S G G + +G HG Sbjct: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHG 1353 Query: 844 QPG--IPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK-------- 893 P G G +S G G ++ + GSG G + + Sbjct: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413 Query: 894 -TQETAVAMHVAANSIQNRPPGYPNMNQ--GGMMGTGPPYGQ-GINS-------MAGMIN 942 TQ + + H ++ G + + G G+ YGQ G S G + Sbjct: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473 Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLG-DVKLTPATKMNNKADGTPKTESKSKKSS 999 Q P S G + + + SP G G P ++ + G ES+S +SS Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSS 1531 Score = 85.9 bits (211), Expect = 4e-16 Identities = 197/889 (22%), Positives = 310/889 (34%), Gaps = 113/889 (12%) Query: 150 FGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP------QQNSH 203 F + + ++ + +++ Q QS G Q G G G P G Q +S+ Sbjct: 161 FQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRG--QCGSGSGQSPNYGQHGSGSGQSSSN 218 Query: 204 D-HGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGA-AAAAGSKPPPSSSASASS 261 D HG + Q + + ++S+ + S G + G G + +G S+S Sbjct: 219 DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSG 278 Query: 262 SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG-DYSGGP 320 SSSS+ Q G+ G G G+ Q + + + + SS+ G G YS G Sbjct: 279 SSSSYGQHGSGSRQSLGHGRQGSGSRQ-SPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGH 337 Query: 321 QDGGAGK----GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR 376 + G+G+ G + S G ++ + + SG + + H S G + GQ + Sbjct: 338 YESGSGQTSGFGQHESGS---GQSSGYSKHGSGSGHSSSQGQHGSTS-GQASSSGQHGSS 393 Query: 377 TPQPSS-------PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQR 429 + Q SS G+ + G +P Q+G SG G G +G + Sbjct: 394 SRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSG 453 Query: 430 YPMTMQGRAQSAMGGLSYTQQIPPYGQQG-----PSGYGQQ-----------------GQ 467 ++ G + S ++ Y Q G SG+GQ G Sbjct: 454 PYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGS 513 Query: 468 TPYYNQQSPHPQQ-----QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ-----LQSSQPP 517 + Y Q +Q + S Q PS + S +Q S P SS+ P Sbjct: 514 SSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGP 573 Query: 518 Y---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPS 571 Y S S HQ+S + S Q ++ H + + QS Q + Sbjct: 574 YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH-----GA 628 Query: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631 T Q +++ Q S SQ + Y QQ Q S+ GS SS GQ Sbjct: 629 TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGH-----SSSYGQHGSGSG 683 Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVST--SGISSSQGEQSNPAQSPFSPHTSPHL 689 S +SG + S G S SG S S G + + ++S S + H Sbjct: 684 WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQH- 742 Query: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749 G S G S + SG + G+ P R G S S + SS Q Sbjct: 743 -GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHS-PSRVRHGSS------SGHSSSHGQH 794 Query: 750 RGYMQRNPQMPQYSSPQ-PGSALSPRQPSGGQIHT--GMGSYQQNSMGSYGPQGGQYGPQ 806 + Y S S + GQ ++ G S +S G +G GQ Sbjct: 795 GSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854 Query: 807 GGYPRQPNYNALPNANYPSAGMAGGINPMGAG-GQM--HGQPG-----IPPYGTLPPGRM 858 G + ++ + ++ A G G+G GQ HGQ G P YG G Sbjct: 855 GQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914 Query: 859 SHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNM 918 +S G G ++ G G G + TQ + + H ++ G + Sbjct: 915 RSSSSGRHGSGSGQSS-----GFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969 Query: 919 NQ--GGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP 965 ++ G G+ YGQ + G S+G + +G + SP Sbjct: 970 SEQHGSSSGSSSSYGQ---------HGSGSRQSLGHGQHGSGSGQSPSP 1009 Score = 85.5 bits (210), Expect = 5e-16 Identities = 203/918 (22%), Positives = 299/918 (32%), Gaps = 138/918 (15%) Query: 14 GNPPPPPPSELKKAEQQQREEAGGEAAAAA--AAERGEMKAAAGQES--------EGPAV 63 G+ P PS + + + G + + ++ RG ++ +G S G + Sbjct: 1942 GSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS 2001 Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGG 123 G Q G G + S G GA +S+G G + ++ G Sbjct: 2002 GYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ--G 2059 Query: 124 GGGGSSDGVGAPPHSAAAALPPPAYG-FGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLA 182 G G S G G + + P+YG G GRS S+ GQ PGL Sbjct: 2060 SGSGQSPGHG---QRGSGSRQSPSYGRHGSGSGRSSSS--------------GQHGPGLG 2102 Query: 183 ALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSS---PRGG 237 +S G G E +G + HG + + Y + +RS + SS R G Sbjct: 2103 --ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG 2160 Query: 238 TPGSGAAAAAG-------SKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPT 290 GSG+ ++G S PS S S S + + G+ G G S++ G + Sbjct: 2161 QHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGS--GSGRSSSRGPYESRS 2218 Query: 291 ATPTL---NQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAA 347 ++ ++ + SSA G G + Q G G ++ Sbjct: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS-----------GQSSTFDQEG 2267 Query: 348 AASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYG------GTNPY 401 +++G + H S SS G Q PS G YG G + Sbjct: 2268 SSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 2327 Query: 402 SQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQG--- 458 S + G SG G G+ + S + Q T G SY Q GQ Sbjct: 2328 SGRHGSGSGQSSGFGH----HESSSWQSSGYTQHGSGSGHSS--SYEQHGSRSGQSSRGE 2381 Query: 459 --------PSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQ---PQSQ 507 S YGQ G Q H Q PS+ H S Q P Sbjct: 2382 RHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS 2439 Query: 508 PPQLQSSQPPY---SQQPSQPPHQQSPAPYPS---QQSTTQQHPQSQPPYSQPQAQSPYQ 561 SS+ PY S S H++S + S Q ++ H + + QS Sbjct: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 2499 Query: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSM--- 618 Q ++ Q +++ Q S SQ + Y +Q Q GS + +PS Sbjct: 2500 GQHG-----ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554 Query: 619 -----TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGALSPGVSTSGISSSQGE 672 SS GQ L S SG G+ S G G S Q Sbjct: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2614 Query: 673 QS--NPAQSPFSPHTSPHLPGIR------------GPSPSP------VGSPASVAQ--SR 710 + + + S S H H G R G SPS +G +S Q S Sbjct: 2615 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 2674 Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP----- 765 SG S +++ GQ +S S S G+ Q S Sbjct: 2675 SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2734 Query: 766 QPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPS 825 Q GS+ G H G GS Q + G +G GQ G + ++ + Sbjct: 2735 QEGSSTGQSSSYG---HRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSG 2791 Query: 826 AGMAGGINPMGAGGQMHG 843 +G + G + G+G G Sbjct: 2792 SGQSSGYSQHGSGSGQDG 2809 Score = 84.3 bits (207), Expect = 1e-15 Identities = 197/808 (24%), Positives = 267/808 (33%), Gaps = 115/808 (14%) Query: 52 AAAGQESEGPAVGPPQPLGK-ELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR 110 +++GQ GP +G G E G S+ G G+G G G ++ + G R Sbjct: 2092 SSSGQH--GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS-RSGQSSRGER 2148 Query: 111 PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170 ++ + G G GS G H G G SPS + + Sbjct: 2149 HGSSSGSSSRYGQHGSGSRQSSG---HGRQ----------GSGSGHSPSRGRHGSGSGHS 2195 Query: 171 QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA-- 228 HG Q G G G GP ++ H Q+ S + SAY Sbjct: 2196 SSHG----------QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 2245 Query: 229 -YALSSPRGGTPG-SGAAAAAGSKPPPSSS----ASASSSSSSFAQQRFGAMGGGGPSAA 282 + G T G S GS SSS S SS SSS+ QQ G+ G PS Sbjct: 2246 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ--GSGSGQSPSRG 2303 Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342 G+ ++ S G+ G SG Q G G S W ++ Sbjct: 2304 RHGSGSGHSSS-----YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE----SSSW-QSSG 2353 Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402 + SG + H S SS G + S G + +G S Sbjct: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413 Query: 403 QQQGPPSGPQQGHGYPGQ-----PYGSQTPQRYPMTMQGRAQSAMG---GLSYTQQIPPY 454 Q PS + G G GQ PYGS + + +G +S G GL + + Sbjct: 2414 GQSPSPSRGRHGSG-SGQSSSYSPYGSGSGWS---SSRGPYESGSGHSSGLGHRESRS-- 2467 Query: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS 514 GQ SGYGQ G + ++ S H Q S Q S H S Q Q S Sbjct: 2468 GQS--SGYGQHGSSSGHS--STHGQHGST--SGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521 Query: 515 QPPYSQQPS----QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570 Y +Q S P H Q + S + S S Q S + Sbjct: 2522 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 2581 Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630 S+ Q ++Y Q S + Y Q Q + GS + S SS GQ Sbjct: 2582 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS-----SSHYGQHGSG- 2635 Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGI--SSSQGEQSNPAQSPFSPHTSPH 688 SR SS GS G+ + S G SG+ SSS G+ + + S Sbjct: 2636 ---SRQSSGHGRQGS------GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS------ 2680 Query: 689 LPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN---------QMPPRPPSGQSDSIMHP 739 RGP S +G + Q SG +A + Q SGQS + Sbjct: 2681 ----RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF--- 2733 Query: 740 SMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQ 799 SS Q Y R Q S A S + S G+ +G G SYG Sbjct: 2734 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQ-----SSSYGQH 2788 Query: 800 GGQYGPQGGYPRQPNYNALPNANYPSAG 827 G G GY + + + +Y G Sbjct: 2789 GSGSGQSSGYSQHGSGSGQDGYSYCKGG 2816 Score = 79.3 bits (194), Expect = 4e-14 Identities = 204/937 (21%), Positives = 286/937 (30%), Gaps = 173/937 (18%) Query: 54 AGQESEGPAVGPPQPLGKEL-QDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPA 112 +GQ S G G Q G+ S G G GSG G P S G G Sbjct: 1434 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP----SRGRHGSGSG 1489 Query: 113 LNNNLTEPPGGGGGGSSDGV--GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFH 170 +++ + G G SS G HS+ G YG+ S+ ++ H Sbjct: 1490 QSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST---H 1546 Query: 171 QQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSH-DHGFPNHQYNSY------------YP 217 QHG + Q G G Q +SH HG + Q + Y + Sbjct: 1547 GQHGSTSGQSSSCGQHGASSG-------QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 1599 Query: 218 NRSAYPPPAPAYALS------SPRGGTPGSGAAAAAGSKPPPSSSASASS---------- 261 R + +P+Y S G GSG ++G SSS +SS Sbjct: 1600 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 1659 Query: 262 -------------------------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLN 296 SSS + Q G+ G G G+ Q Sbjct: 1660 SSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQ-------- 1711 Query: 297 QLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQR 356 SPS R G G S G G+G+ +++ G + R Sbjct: 1712 ----SPSRGRHGSGL-GHSSSHGQHGSGSGR-------------------SSSRGPYESR 1747 Query: 357 SHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHG 416 S H+ + G G A + S + + G + Q+G +G HG Sbjct: 1748 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 1807 Query: 417 YPGQPYGSQTPQRYPMTMQGRAQSAMGGL--SYTQQIPPYGQQGP------------SGY 462 G GS Y G QS G S + YGQ G SG Sbjct: 1808 QHGS--GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865 Query: 463 GQQGQTPYYNQQS--PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ 520 GQ ++ S Q S S H S Q Q S Y Q Sbjct: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ 1925 Query: 521 QPSQPPHQ-----------QSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569 S QSP+P + + S PY S + P Sbjct: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWS-----SSRGPY 1980 Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629 S + +S+ Q + Y Q + GS AS S G + Sbjct: 1981 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-ASGQSSSCGQHGASSGQS 2039 Query: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ--SNPAQSPFSPHTSP 687 S S SG G+ SPG G S Q + + S S + Sbjct: 2040 SSHGQHGSGSSQSSGY---GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQ 2096 Query: 688 HLPGIR-----GPSPSPVGSPASVAQ--SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740 H PG+ G S G +S +Q S SG S G++ SGQS Sbjct: 2097 HGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR------SGQSS---RGE 2147 Query: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG 800 + SS Y Q Q S + S PS G+ G GS +S G +G Sbjct: 2148 RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR--HGSGSGHSSSHGQHGSGS 2205 Query: 801 GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG----------GQMHGQPGIPPY 850 G+ +G Y + ++++ + +G + + G+G G GQ Sbjct: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265 Query: 851 GTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 G+ S S G G + ++ Q GSG P Sbjct: 2266 EGSSTGQSS--SHGQHGSGSSQSSSYGQQGSGSGQSP 2300 Score = 61.2 bits (147), Expect = 1e-08 Identities = 152/705 (21%), Positives = 223/705 (31%), Gaps = 79/705 (11%) Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393 S +G + + ++ G S +P G GQ + S G + + Sbjct: 176 SSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHK 235 Query: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453 G + Q G SG G+G G G + + G + S S ++Q Sbjct: 236 SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295 Query: 454 YGQQG------------------PSGYGQQGQTPYYNQQSPHPQQ---------QQPPYS 486 +G+QG S +GQ G Y+ H + Q S Sbjct: 296 HGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS 355 Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546 Q + H S Q Q S Q S Q Q S Q + +H Sbjct: 356 GQSSGYSKHGSGSGHSSSQGQHGS-TSGQASSSGQHGSSSRQSSSY---GQHESASRHSS 411 Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS----QQTAYSQQRFPPPQE 602 + +S QSP Q+ S S Q +S S + YS F + Sbjct: 412 GRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS-SGFGHHES 470 Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM-GTEGALSPGV 661 S+ S G + S SS GQ SR +GS G+ S G Sbjct: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH 530 Query: 662 STSGISSSQG--------EQSNPAQSPFSPH-TSPHLPGIRGPSPSPVGSPASVA--QSR 710 S G S Q E + S + PH RGP S G + + +SR Sbjct: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590 Query: 711 SGPLSPAAVPGNQM-------PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYS 763 SG S G+ SGQS S + + + Q +Y Sbjct: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650 Query: 764 SPQPGSALSPRQPSGGQIHTGMGSYQQNSMG-----SYGPQG---GQ---YGPQGGYPRQ 812 GS SP + G SY Q+ G S GP G GQ +G + G + Sbjct: 651 QQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710 Query: 813 PNYNALPNANYPSAGMA--GGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGP 870 Y+ + + S+G G + + + HG G SH S G+ G Sbjct: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS 770 Query: 871 NMANMPPQV----GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926 + P +V SG G T ++ H + S Q G G+ Sbjct: 771 GSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHE------SGS 824 Query: 927 GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971 G Y Q S +G + QG S G +++ ++S + G Sbjct: 825 GQGYSQH-GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868 Score = 35.8 bits (81), Expect = 0.50 Identities = 92/435 (21%), Positives = 147/435 (33%), Gaps = 36/435 (8%) Query: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSD 1196 GSGS Q P Q S S + + + S G+ S+ G ++ + S Sbjct: 1589 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648 Query: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNG-G 1255 S Q + + GY + S R + S GS SSG G G G Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708 Query: 1256 MGDPYSRAA-GPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP 1314 G SR G GLG+ + H +G R + GP + S + + Sbjct: 1709 SGQSPSRGRHGSGLGHSS----SHGQHGSGSGRSSSR---GPYESRSGHSS----VFGQH 1757 Query: 1315 DSGMYSPSRYPPQQQQQ----QQQRHDSYGNQFST---QGTPSGSPFPSQQTTMYQQQQQ 1367 +SG S Y Q +H S Q ST +G+ +G Q Q Sbjct: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 1817 Query: 1368 NYKRPMDGTYGPPAKRHEGEMYSVPYSTGQ-GQPQQQQLPPAQPQPASQQQAA-----QP 1421 +Y + G+ P++ G S GQ G + S Q + Sbjct: 1818 SYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 1877 Query: 1422 SPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481 S Q Y Q+G+ + +++ E+ + Q+ Q G S + Q + Sbjct: 1878 SWQSSGYTQHGSG--SGHSSSYEQHGSRSGQSSRGEQHGSS--SGSSSSYGQHGSGSRQS 1933 Query: 1482 GGPIQASAEVAQQGTMWQGRN------DMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHT 1535 G Q + Q + +GR+ +Y S S+ +GP G + + H Sbjct: 1934 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHR 1993 Query: 1536 DQRANHEGSWPSHGT 1550 + R+ + HG+ Sbjct: 1994 ESRSGQSSGYGQHGS 2008 Score = 35.0 bits (79), Expect = 0.85 Identities = 91/435 (20%), Positives = 148/435 (34%), Gaps = 36/435 (8%) Query: 1137 GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSD 1196 GSGS Q P Q S S + + + S PG+ S+ G ++ + S Sbjct: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118 Query: 1197 STFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNG-G 1255 S Q + + GY + S R + S GS SSG G G G Sbjct: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178 Query: 1256 MGDPYSRAA-GPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNP 1314 G SR G G G+ + H +G R + GP + S + + Sbjct: 2179 SGHSPSRGRHGSGSGHSS----SHGQHGSGSGRSSSR---GPYESRSGHSS----VFGQH 2227 Query: 1315 DSGMYSPSRYPPQQQQQ----QQQRHDSYGNQFST---QGTPSGSPFPSQQTTMYQQQQQ 1367 +SG S Y Q +H S Q ST +G+ +G Q Q Sbjct: 2228 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS 2287 Query: 1368 NYKRPMDGTYGPPAKRHEGEMYSVPYSTGQ-GQPQQQQLPPAQPQPASQQQAA-----QP 1421 +Y + G+ P++ G S GQ G + S Q + Sbjct: 2288 SYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS 2347 Query: 1422 SPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481 S Q Y Q+G+ + +++ E+ + Q+ + G S + Q + Sbjct: 2348 SWQSSGYTQHGSG--SGHSSSYEQHGSRSGQSSRGERHGSS--SGSSSSYGQHGSGSRQS 2403 Query: 1482 GGPIQASAEVAQQGTMWQGRN------DMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHT 1535 G Q + Q + +GR+ +Y+ S S+ +GP G + + H Sbjct: 2404 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHR 2463 Query: 1536 DQRANHEGSWPSHGT 1550 + R+ + HG+ Sbjct: 2464 ESRSGQSSGYGQHGS 2478 Score = 33.9 bits (76), Expect = 1.9 Identities = 87/445 (19%), Positives = 147/445 (33%), Gaps = 60/445 (13%) Query: 1137 GSGSMQGPQTPQ-----STSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAF 1191 GSGS Q P + SSS + G + ++ PH + S G Sbjct: 653 GSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS-------GQSSGFGHKS 705 Query: 1192 NDGSDSTFQKRNS-MTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQ 1250 G S + + S + + GY+ + S R + S GS SSG Sbjct: 706 GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGH 765 Query: 1251 GPNG------------GMGDPYSRAAGP-GLGNVAMGPRQHYPYGGP----YDRVRTEPG 1293 G G G +S + G G G HY G + + + G Sbjct: 766 GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSG 825 Query: 1294 IG------PEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347 G G+ S+ + + SG + S Q +H+S + S +G Sbjct: 826 QGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSS----SGQSSSYGQHESASHHASGRG 881 Query: 1348 TP-SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLP 1406 SGS Q Q+ + + P G +G + R S + +G GQ Sbjct: 882 RHGSGS---GQSPGHGQRGSGSGQSPSYGRHGSGSGRSSS---SGRHGSGSGQSSGFGHK 935 Query: 1407 PAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSA 1466 + Q + Q S Y Q+G+ + + R G + +G+ Sbjct: 936 SSSGQSSGYTQHGSGSGHSSSYEQHGSR-----SGQSSRSEQHGSSSGSSSSYGQH---- 986 Query: 1467 PPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG-SAPQGPAYHG 1525 G+ ++Q++ G S ++ G G + R +G S+ +GP G Sbjct: 987 --GSGSRQSLGHGQHGSGSGQSPSPSR-GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESG 1043 Query: 1526 VNRTDEMLHTDQRANHEGSWPSHGT 1550 + + H + R+ + HG+ Sbjct: 1044 SGHSSGLGHRESRSGQSSGYGQHGS 1068 Score = 32.7 bits (73), Expect = 4.2 Identities = 88/426 (20%), Positives = 139/426 (32%), Gaps = 44/426 (10%) Query: 1136 AGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGS 1195 +GSG T S S + K + S+ +SQ G S+ G Q G Sbjct: 210 SGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGS--GSGHSSGYG-QHGSRSGQ 266 Query: 1196 DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAP-----GSDPFMSSGQ 1250 S ++ S + G S R S + GS R++P GS SS Sbjct: 267 SSRGERHRSSS---GSSSSYGQHGSGSRQSLGHGRQGSGS-RQSPSHVRHGSGSGHSSSH 322 Query: 1251 GPNG-GMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNL 1309 G +G G YSR G+ G Q +G + E G G S Sbjct: 323 GQHGSGSSYSYSR------GHYESGSGQTSGFG------QHESGSGQSSGYSKHGSGSGH 370 Query: 1310 MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSG----SPFPSQQTTMYQQQ 1365 S G S Q ++ SYG S SG S Q Q+ Sbjct: 371 SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRG 430 Query: 1366 QQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPAS-QQQAAQPSPQ 1424 + + P G +G R S PY +G G + + +S Q S Sbjct: 431 SGSGQSPSSGQHGTGFGRSSS---SGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487 Query: 1425 QDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGP 1484 + Q+G+ ++ + AG + +G+ G+ ++Q++ G Sbjct: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSS-----YGQH------GSGSRQSLGHSRHGSG 536 Query: 1485 IQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGS 1544 S ++ R +Y S S+ +GP G + + H + R+ Sbjct: 537 SGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSG 596 Query: 1545 WPSHGT 1550 + HG+ Sbjct: 597 YGQHGS 602 Score = 31.6 bits (70), Expect = 9.4 Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 77 AESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPP 136 A S G G G S G G+ ++ G +++ G G GSS G Sbjct: 2706 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY----GHRGSGSSQSSGYGR 2761 Query: 137 HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYA 196 H A + G +GR S +++ + QHG Q G G G + Y+ Sbjct: 2762 HGAGS-------GQSLSHGRHGSGSGQSSS---YGQHGSGSGQSSGYSQHGSGSGQDGYS 2811 Query: 197 GPQQNS-HDHGFPNHQYNSYYPNRSAY 222 + S HD G + S+ + S Y Sbjct: 2812 YCKGGSNHDGGSSGSYFLSFPSSTSPY 2838 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 107 bits (266), Expect = 2e-22 Identities = 130/470 (27%), Positives = 175/470 (37%), Gaps = 74/470 (15%) Query: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375 +GGP G AG G M + G + + A G S P PG+SG +A Sbjct: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143 Query: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430 TPQ + Q+ + Q + QQQ QQ Q Q+ Q++ Sbjct: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200 Query: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490 +Q + Q I + Q QQ Q Q QQQQ QQ Sbjct: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260 Query: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549 Q AQP QQ P QP P + P QQ H Q P P P Q Q P P Sbjct: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319 Query: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597 P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q Sbjct: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379 Query: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL 657 P ++SQ SS P ++S GQ+ P S+P + + Sbjct: 380 APGVQVSQ-------SSLPMLSSPSPGQQ------VQTPQSMPP----------PPQPSP 416 Query: 658 SPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPV--GSPASVAQSRSGPLS 715 PG +S +S+ P+ S F P SP PS SPV +P + + GPL+ Sbjct: 417 QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ------PSQSPVTARTPQNFSVPSPGPLN 470 Query: 716 PAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765 P + M P SS A+++ Y+ + Q+ +Y P Sbjct: 471 TPVNPSSVMSPA---------------GSSQAEEQQYLDKLKQLSKYIEP 505 Score = 66.6 bits (161), Expect = 3e-10 Identities = 117/502 (23%), Positives = 164/502 (32%), Gaps = 100/502 (19%) Query: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308 G G G MG P S + P G M P +ST PQ Sbjct: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSM-------------------AVVSTATPQTQ 152 Query: 1309 LM-------PSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPS----Q 1357 L + QQQQQQQQ+ QF Q + F + Q Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ-----QQFQAQQSAMQQQFQAVVQQQ 207 Query: 1358 QTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSV------PYSTGQGQPQQQQLPPAQPQ 1411 Q QQQQQ + + ++ + ++ + Q Q QQQQ Q Q Sbjct: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267 Query: 1412 PASQQ---QAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPP 1468 P QQ Q QP P Q + Q + +P PQ Q P P Sbjct: 268 PPIQQPPMQQPQPPPSQALPQQLQQMH-----HTQHHQPP--PQPQQP----------PV 310 Query: 1469 GTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNR 1528 N +PPQ P+ + A+ A G M + + + A Q P V + Sbjct: 311 AQNQPSQLPPQSQTQPLVSQAQ-ALPGQMLYTQPPLKFVRAPM----VVQQPPVQPQVQQ 365 Query: 1529 TDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVP------PMTRPPPSNYQPPPSMQNHI 1582 + T Q A P S+P P P + PPP P P + Sbjct: 366 QQTAVQTAQAAQMVAPGVQVSQSSLPM-LSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424 Query: 1583 PQVS-SPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITF 1641 P + S P P P SPS P A P S +P P+ P+ + Sbjct: 425 PNSNVSSGPAPSPSSFLPSPSPQP----SQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS 480 Query: 1642 PPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSI 1701 P GS +A + + + K I E R M++ D N Sbjct: 481 PAGSSQAEEQQYLDKLKQLSKYI---EPLRRMIN-------------------KIDKNED 518 Query: 1702 MTFNLSQLPGLLELLVEYFRRC 1723 +LS++ LL++L + +RC Sbjct: 519 RKKDLSKMKSLLDILTDPSKRC 540 Score = 62.4 bits (150), Expect = 5e-09 Identities = 105/423 (24%), Positives = 139/423 (32%), Gaps = 99/423 (23%) Query: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486 P ++ G + G+ + P G G GQ + Q P P+S Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140 Query: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542 S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q Sbjct: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197 Query: 543 QHPQSQPPYSQPQAQSPYQQQQP-------------------QQPAPSTLSQQAAYPQPQ 583 Q Q+ Q Q Q QQQQ Q+ A L QQ Q Q Sbjct: 198 QQFQAVVQQQQ-QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256 Query: 584 SQQSQQTAYS---------QQRFPP-----PQELSQDSFGSQ------------ASSAPS 617 QQ QQ + QQ PP PQ+L Q A + PS Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316 Query: 618 MTSSKGGQEDMNLSLQSRPSSL------------------PDLSGSIDDLPMGTEGA--- 656 + + + Q+ P + P + + + A Sbjct: 317 QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAA 376 Query: 657 --LSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPL 714 ++PGV S S +P Q +P + P P PSP P G P+S S Sbjct: 377 QMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP---QPSPQP-GQPSSQPNSNVSS- 431 Query: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPR 774 PA P + +P PS P +QS + R PQ +S P PG +P Sbjct: 432 GPAPSPSSFLP--SPS--------PQPSQSPVT------ARTPQ--NFSVPSPGPLNTPV 473 Query: 775 QPS 777 PS Sbjct: 474 NPS 476 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 106 bits (264), Expect = 3e-22 Identities = 236/1002 (23%), Positives = 321/1002 (32%), Gaps = 140/1002 (13%) Query: 54 AGQESEGPAVGPPQPLGKELQDGAESNGGGGG--------GGAGSGGGPGAEPDLKNSNG 105 AG+ + GPP P G G G G G G G PG + + + Sbjct: 257 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 316 Query: 106 NAGPRPALNNNL------TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQP-YGRSP 158 N P P L T P G G +DG P A P P G P + +P Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP-----AGPPGPVGPAGGPGFPGAP 371 Query: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPN 218 A A G Q G + G G P AG N G P + ++ P Sbjct: 372 GAKGEAGPTGARGPEGAQGPRG----EPGTPGSPGP-AGASGNPGTDGIPGAKGSAGAPG 426 Query: 219 RSAYP-------PPAPAYALS--SPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQ 269 + P PP P A P+G T G A G + P A Sbjct: 427 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ------- 479 Query: 270 RFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGP 329 GA G G G +P + A G +G+PG D GP+ +GP Sbjct: 480 --GAPGPAGEEGKRGARGEPGGVGPIGP--PGERGAPGNRGFPGQDGLAGPKGAPGERGP 535 Query: 330 ADMASQCWG-------AAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381 + +A A +G + P G+ G G+P P P Sbjct: 536 SGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP--GPPGPQ 593 Query: 382 SPMDQMGKMR-PQPYG--GTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTPQRYPMTMQG 436 Q G M P P G G + ++G P P G PG+ G+ P Sbjct: 594 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL-RGLPGKDGETGAAGPPGPAGPAGE 652 Query: 437 RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496 R + G S Q +P G GP G G + ++ P P + P + Sbjct: 653 RGEQGAPGPSGFQGLP--GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 710 Query: 497 QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA 556 Q P+ P + P + P+ PP Q P + P + Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 770 Query: 557 QSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQ-------TAYSQQRFPPPQELSQDSFG 609 + P + L+ P P ++ A S P E + Sbjct: 771 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830 Query: 610 SQASSA--PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667 A A P G + + + Q + P G P G G P +G Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-----PSGAPGPQGP-TGVTGPK 884 Query: 668 SSQGEQSNPAQSPF-------SPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAV 719 ++G Q P + F P S PG GP P P G A+ SGP A Sbjct: 885 GARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-PGPSGKDGPKGARGDSGPPGRAGE 943 Query: 720 PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGG 779 PG Q P PP + + P + S A+ P PQ + Q G P Q G Sbjct: 944 PGLQGPAGPPGEKGE----PGDDGPSGAE-------GPPGPQGLAGQRGIVGLPGQ-RGE 991 Query: 780 QIHTGMGSY-----QQNSMGSYGPQG--GQYGPQG--GYPRQPNYNALPNANYP-----S 825 + G+ +Q + G+ G +G G GP G G +P P A+ P + Sbjct: 992 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051 Query: 826 AGMAGGINPMGAGGQMHGQPGIP--PYGTLPPGRMSHASMGNR--PYGPNMANMPPQVGS 881 AG+ G GA G G PG P P P G+ P GP+ P Sbjct: 1052 AGVKGDRGETGAVGAP-GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS----GPAGAR 1106 Query: 882 GMCPPPGGMNRKTQ-----ETAVAMHVAANSIQNRP-PGYPNMNQGGMMGTGP------- 928 G+ P G K + E + H +Q P P P+ +QG GP Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166 Query: 929 ----PYGQ-GINSMAGMINPQGPPYSMGGTMANNSAGMAASP 965 P G+ G N + G I P GP G T G P Sbjct: 1167 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208 Score = 102 bits (253), Expect = 6e-21 Identities = 210/834 (25%), Positives = 269/834 (32%), Gaps = 156/834 (18%) Query: 26 KAEQQQREE---AGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKEL------QDG 76 K EQ + E AG + A A E G+ A GP +GPP G QDG Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDG 522 Query: 77 AESNGGGGG--------GGAGSGGGPG--AEPDLKNSNGNAG-PRPALNNNLTEPPGGGG 125 G G G G+ G PG EP L + G G P A P G G Sbjct: 523 LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 582 Query: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL- 184 DG PP A P GF P G + A + G +PGL L Sbjct: 583 ---EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG-------EKGLPGAPGLRGLP 632 Query: 185 ----QSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 ++G G P AGP + G P P PP P G PG Sbjct: 633 GKDGETGAAGPPGP-AGPAGERGEQGAPGPSGFQGLPG----PPGPPGEGGKPGDQGVPG 687 Query: 241 S----GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPT 294 G G + P S + + G G GP A G G P P Sbjct: 688 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 747 Query: 295 LNQL--------LTSPSSARGYQGYPGGDYSGGPQDGGAG-------KGPADMASQCWGA 339 L + + P RG G G + + G +DGG G GPA + Sbjct: 748 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG-KDGGRGLTGPIGPPGPAGANGEKGEV 806 Query: 340 AAAAAAAAAASGGAQ-QRSHHAPMSP----GSSGGGGQPLARTPQ-PSSPMDQMGKMRPQ 393 A +A + GA +R P P G G GQP A+ Q + G PQ Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866 Query: 394 -PYGGTNPYSQQQGPP--SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ 450 P G P QGP +GP+ G G P + P A +G Sbjct: 867 GPSGAPGP----QGPTGVTGPKGARGAQGPPGATGFPG---------AAGRVGPPGSNGN 913 Query: 451 IPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510 P G GPSG + G P P + +P Q P P + +P P Sbjct: 914 PGPPGPPGPSG--KDGPKGARGDSGP------PGRAGEPGLQGPAGPPGEKGEPGDDGPS 965 Query: 511 LQSSQPPYSQQ----------PSQPPHQQSPA-PYPSQQSTTQQHPQSQ----------P 549 + PP Q P Q + P P PS + Q P + P Sbjct: 966 -GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 1024 Query: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609 P A P ++ P P A + + + A P P G Sbjct: 1025 PGLTGPAGEPGREGSPGADGPPGRDGAAGV---KGDRGETGAVGAPGAPGPP-------G 1074 Query: 610 SQASSAPSMTSSKGGQEDMNLSL-QSRPSSLPDLSGSIDDLPMGTEG-ALSPGV----ST 663 S + P+ G+ + S P+ + G P G +G A PG Sbjct: 1075 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG--PRGDKGEAGEPGERGLKGH 1132 Query: 664 SGISSSQGEQSNP-------AQSPFSPHTSPHLPGIRGPS--------PSPVGSPASVAQ 708 G + QG P A P P PG GPS P P+G P + Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP--R 1190 Query: 709 SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762 RSG PA PGN PP PP P ++ S+ A G ++ P QY Sbjct: 1191 GRSGETGPAGPPGNPGPPGPPGPPG-----PGIDMSAFA-GLGPREKGPDPLQY 1238 Score = 101 bits (252), Expect = 7e-21 Identities = 243/1002 (24%), Positives = 316/1002 (31%), Gaps = 229/1002 (22%) Query: 14 GNPPPP----PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPL 69 GNP PP PP + AGG A A+ G M+ G GP GPP P Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM--GPR-GPPGP- 214 Query: 70 GKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129 G G G G PG EP +G GPR PPG G Sbjct: 215 ------------AGAPGPQGFQGNPG-EPGEPGVSGPMGPRG--------PPGPPGKPGD 253 Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189 DG P A PP G G +PGL ++ G Sbjct: 254 DGEAGKPGKAGERGPPGPQG----------------------ARGFPGTPGLPGVKGHRG 291 Query: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249 Y G + G P + S P + P P L RG T +GAA A G+ Sbjct: 292 -----YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346 Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309 P G G GP GG P A + P+ ARG + Sbjct: 347 DGQP------------------GPAGPPGPVGPAGGPGFPGAPGAKGE--AGPTGARGPE 386 Query: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369 G G G P G+ GPA + A S GA PG +G Sbjct: 387 GAQGP--RGEPGTPGS-PGPAGASGN---PGTDGIPGAKGSAGA----------PGIAGA 430 Query: 370 GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTP 427 G P R P P P G T P GP+ G PG G Q P Sbjct: 431 PGFPGPRGP-------------PGPQGATGPL--------GPKGQTGEPGIAGFKGEQGP 469 Query: 428 QRYPMTMQGRAQSAMGGLSYTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486 + P G + Q P P G++G G +G+ P P ++ P + Sbjct: 470 KGEP------------GPAGPQGAPGPAGEEGKRG--ARGEPGGVGPIGP-PGERGAPGN 514 Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546 + P Q A P + P + P + + P +P P + T + Sbjct: 515 RGFPGQDGLAGP--KGAPGERGPSGLAGPKGANGDPGRP----GEPGLPGARGLTGRPGD 568 Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606 + P + +P + +P P P Q A QP FP P+ Sbjct: 569 AGPQGKVGPSGAPGEDGRPGPPGP-----QGARGQP----------GVMGFPGPKG---- 609 Query: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM--GTEGALSPGVSTS 664 A+ P KG LP G + LP G GA P + Sbjct: 610 -----ANGEPGKAGEKG---------------LPGAPG-LRGLPGKDGETGAAGPP-GPA 647 Query: 665 GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAVPGNQ 723 G + +GEQ P S F P P G P G P A GP PG + Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 707 Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783 P + + P + D P P + PG P + I Sbjct: 708 GSPG-----AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 762 Query: 784 GMGSYQQNSMGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGINPMG 836 G + +G GP+G G+ G +G G P N P G AG G Sbjct: 763 PKGD--RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP-GPAGSAGARG 819 Query: 837 AGGQMHGQPGIP-PYGTL-PPG-------RMSHASMGNR-------PYGPNMANMPPQVG 880 A G+ G+ G P P G PPG + G + P GP+ A PQ Sbjct: 820 APGE-RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP-GPQGP 877 Query: 881 SGMCPPPGGMNRKTQETAVAMHVAANSI-------QNRPPGYPNMN-----QGGMMGTGP 928 +G+ P G + A AA + PPG P + +G +GP Sbjct: 878 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 937 Query: 929 PYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 P G G+ P GPP G + +G P GL Sbjct: 938 P---GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976 Score = 84.3 bits (207), Expect = 1e-15 Identities = 144/574 (25%), Positives = 176/574 (30%), Gaps = 67/574 (11%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAER---GEMKAAAGQESEGP-- 61 P+ L PP PP K +Q EAG ER GE + Q +GP Sbjct: 661 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720 Query: 62 ------------AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGP 109 A GP P G + G + G G AG G G D+ P Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGM-PGERGAAGIAGPKGDRGDVGEKGPEGAP 779 Query: 110 RPALNNNLT---EPPGGGGGGSSDGVGAPPHSAAAA------------LPPPAYGFGQPY 154 LT PPG G G PP A +A PP GF P Sbjct: 780 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839 Query: 155 GR--SPSAVAAAAAAVFHQQHG--GQQSPGLAALQSGGGG--GLEPYAGPQQNSHDHGFP 208 G P A A G G Q P A G G G + G Q GFP Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899 Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ 268 P + P P P G + G A G PP + + Sbjct: 900 GAAGRVGPPGSNGNPGP------PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 953 Query: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPG-GDYSGGPQDGGAGK 327 G G GPS A G P P ++ P RG +G+PG SG P GA Sbjct: 954 GEKGEPGDDGPSGA-EGPPGPQGLAGQRGIVGLPGQ-RGERGFPGLPGPSGEPGKQGAPG 1011 Query: 328 GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR-------TPQP 380 D G A ++ S A PG G G R P Sbjct: 1012 ASGDRGPP--GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1069 Query: 381 SSPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438 P G P G + QGP PSGP G G P G + + R Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG-PQGPRGDKGEAGEPGERG 1128 Query: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPH-PQQQQPPYSQQPPSQTPHAQ 497 G + Q +P G GPS G QG + P P P + + P Sbjct: 1129 LKGHRGFTGLQGLP--GPPGPS--GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP--G 1182 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531 P P+ + + + PP + P PP P Sbjct: 1183 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216 Score = 83.6 bits (205), Expect = 2e-15 Identities = 138/495 (27%), Positives = 158/495 (31%), Gaps = 117/495 (23%) Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75 PP P + +K E AG A A ERGE GPP P G Sbjct: 793 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE-------------TGPPGPAGFAGPP 839 Query: 76 GAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133 GA+ G G G AG G GA P + +G GP+ +T P G G G Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGAT 896 Query: 134 APPHSAAAALPPPAYGF-GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192 P +A PP + G G P PS A G PG A G GL Sbjct: 897 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-----RGDSGPPGRA-----GEPGL 946 Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAAGSK 250 + AGP + G A PP P L+ RG G PG Sbjct: 947 QGPAGPPGEKGEPGDDGPS--------GAEGPPGP-QGLAGQRGIVGLPGQRGERGFPGL 997 Query: 251 PPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTLNQLLTSPSSARGYQ 309 P PS G P A+G G P P P LT P+ G + Sbjct: 998 PGPSGEPGKQ----------------GAPGASGDRGPPGPVGPPG----LTGPAGEPGRE 1037 Query: 310 GYPGGDYSGGPQDGGAG----------------------KGPA-DMASQCWGAAAAAAAA 346 G PG D G +DG AG GPA Q A A Sbjct: 1038 GSPGADGPPG-RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096 Query: 347 AAASGGAQQRSHHAPMSP-GSSGGGGQP-------------LARTPQPSSPMDQMGKMRP 392 SG A R P P G G G+P L P P P G P Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156 Query: 393 Q-PYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ 449 P G P GP PSG +G PG P G P R +S G + Sbjct: 1157 AGPSGPRGP----PGPVGPSGKDGANGIPG-PIGPPGP---------RGRSGETGPAGPP 1202 Query: 450 QIP-PYGQQGPSGYG 463 P P G GP G G Sbjct: 1203 GNPGPPGPPGPPGPG 1217 Score = 64.3 bits (155), Expect = 1e-09 Identities = 155/667 (23%), Positives = 206/667 (30%), Gaps = 93/667 (13%) Query: 364 PGSSGGGGQP--LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP 421 PG G G+P + P P G Q G ++G P GP+ G PG P Sbjct: 100 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP-GPRGRDGEPGTP 158 Query: 422 YGSQTPQ------------RYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTP 469 P + M G GG P G GP G P Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 218 Query: 470 YYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQ 529 P Q P +P P P P +P + P PP Q Sbjct: 219 -----GPQGFQGNPGEPGEPGVSGPMG-PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272 Query: 530 SPAPYPSQQSTT-----QQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577 +P + +P ++ P + ++ SP + P P L + Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332 Query: 578 AYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPS 637 P + Q P + G AP G P Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392 Query: 638 SLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP 697 P GS P G G +PG T GI ++G P + +P PG RGP P Sbjct: 393 GEPGTPGSPG--PAGASG--NPG--TDGIPGAKGSAGAPGIAG-----APGFPGPRGP-P 440 Query: 698 SPVGSPASVA-QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRN 756 P G+ + + ++G A G Q P P + RG Sbjct: 441 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG----- 495 Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG------- 807 +PG + P P G + G + G GP+G G+ GP G Sbjct: 496 ---------EPGG-VGPIGPPGERGAPGNRGFPGQD-GLAGPKGAPGERGPSGLAGPKGA 544 Query: 808 -GYPRQPNYNALPNANYPS-----AGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHA 861 G P +P LP A + AG G + P GA G+ G+PG P P G Sbjct: 545 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE-DGRPGPPG----PQGARGQP 599 Query: 862 SMGNRPYGPNMANMPPQVGS--GMCPPPG--GMNRKTQETAVA-----MHVAANSIQNRP 912 + P GP AN P G+ PG G+ K ET A A + Sbjct: 600 GVMGFP-GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658 Query: 913 PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972 PG P+ QG GPP G G+ G P +G G SP GL Sbjct: 659 PG-PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 717 Query: 973 VKLTPAT 979 + P T Sbjct: 718 PRGLPGT 724 Score = 64.3 bits (155), Expect = 1e-09 Identities = 88/351 (25%), Positives = 113/351 (32%), Gaps = 43/351 (12%) Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG-----GEAAAAAAAERGEMKAAAGQ 56 A +V P ++ PP PP K + R ++G GE A K G Sbjct: 902 AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 961 Query: 57 ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG-GGPGAEPDLKNSNGNAG----PRP 111 + A GPP P G Q G G G G GP EP + + G +G P P Sbjct: 962 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021 Query: 112 ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYG----FGQPYGRSPSAVAAAAAA 167 LT P G G S G PP AA G G P P A Sbjct: 1022 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1081 Query: 168 VFHQ---QHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQ----YNSYYPNRS 220 Q G Q P + G G++ GP+ + + G P + + + + Sbjct: 1082 TGKQGDRGEAGAQGP-MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1140 Query: 221 AYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPS 280 PP P+ G SG A +G + PP S A G +G GP Sbjct: 1141 LPGPPGPS-------GDQGASGPAGPSGPRGPP---GPVGPSGKDGANGIPGPIGPPGPR 1190 Query: 281 AAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPAD 331 G T P G G PG G AG GP + Sbjct: 1191 GRSGETGP-----------AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPRE 1230 Score = 49.7 bits (117), Expect = 3e-05 Identities = 91/359 (25%), Positives = 113/359 (31%), Gaps = 38/359 (10%) Query: 648 DLPMGTEGALSPG--VSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGPSPSPV 700 ++P G + P + SG +G++ P P P G +GP Sbjct: 79 EIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRG 138 Query: 701 GSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMP 760 A G PGN PP PP P + + AQ G Sbjct: 139 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP----PGLGGNFAAQMAGGFDEKAGGA 194 Query: 761 QYSSPQ-PGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG--GYPRQPNY 815 Q Q P + PR P G G +Q N G G G G GP+G G P +P Sbjct: 195 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNP-GEPGEPGVSGPMGPRGPPGPPGKPGD 253 Query: 816 NALPNANYPS-AGMAGGINPMGAGGQMHGQPGIPPYGTLP--PGRMSHASMGNRPYGPNM 872 + A P AG G P GA G G PG+P PG P Sbjct: 254 DG--EAGKPGKAGERGPPGPQGARG-FPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE 310 Query: 873 ANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA--NSIQNRPPGYPNMNQGGMMGTGPPY 930 + P + GS P G+ + T A A N Q P G P GP Sbjct: 311 SGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP-------VGPAG 363 Query: 931 GQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP 989 G G G GP + G A G +P G P T DG P Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGT------DGIP 416 Score = 39.3 bits (90), Expect = 0.045 Identities = 80/353 (22%), Positives = 110/353 (31%), Gaps = 50/353 (14%) Query: 1108 ERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAS 1167 E+GE PP +A ++ + + P G GP + E G+ A Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861 Query: 1168 TPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYE 1227 P Q P S + G Q G R + P PG + +G Sbjct: 862 APGPQGP-------SGAPGPQGP--TGVTGPKGARGAQGP-PGATGFPGAAGRVGPPGSN 911 Query: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD--PYSRAAGPGLGNVAMGPRQHYPYGGPY 1285 N P G P S GP G GD P RA PGL A P + Sbjct: 912 GNPGPPG--------PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-------- 955 Query: 1286 DRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFS 1344 + EPG GP G + G P P + +G P Q+ ++ + Sbjct: 956 ---KGEPGDDGPSG--AEGPPGPQGL-----AGQRGIVGLPGQRGERGFPGLPGPSGEPG 1005 Query: 1345 TQGTPS-----GSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQ 1399 QG P G P P + + + G GPP + + TG Sbjct: 1006 KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVG 1065 Query: 1400 PQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQ 1452 PP P PA P+ +Q + G P + R GPQ Sbjct: 1066 APGAPGPPGSPGPAG------PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ 1112 Score = 35.0 bits (79), Expect = 0.85 Identities = 85/364 (23%), Positives = 106/364 (29%), Gaps = 60/364 (16%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPP----LPGM-------- 1179 PP PAG +G Q S G PP P Q P PG+ Sbjct: 643 PPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERG 702 Query: 1180 --SRSNSVGIQDAFN----DGSDSTFQKRNSMTP--NPGYQPSMNTSDMMGRMSYEPNKD 1231 S G Q G+ T + + P PG Q M G Sbjct: 703 FPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 762 Query: 1232 PYGSM----RKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDR 1287 P G K P P G+G G +G P A G V GP GP Sbjct: 763 PKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV--GP------PGPAGS 814 Query: 1288 VRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347 G G TG P P P + P + +Q + QG Sbjct: 815 AGARGAPGERG--ETGPPGPAGFAGPPGA-----DGQPGAKGEQGEAGQKGDAGAPGPQG 867 Query: 1348 TPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP 1407 PSG+P P T + + G GPP P + G+ P P Sbjct: 868 -PSGAPGPQGPTGV------TGPKGARGAQGPPGAT------GFPGAAGRVGPPGSNGNP 914 Query: 1408 AQPQPASQQQAAQPSPQQDVYNQYGNA-YPATATAATERRPAGGP-QNQFPFQFGRDRVS 1465 P P PS + G++ P A + PAG P + P G Sbjct: 915 GPPGPPG------PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 968 Query: 1466 APPG 1469 PPG Sbjct: 969 GPPG 972 Score = 34.3 bits (77), Expect = 1.4 Identities = 100/414 (24%), Positives = 132/414 (31%), Gaps = 60/414 (14%) Query: 1109 RGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAST 1168 RG PP A + ++ PP G+ GP P GD PP A Sbjct: 887 RGAQGPP---GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943 Query: 1169 PHSQIPPLPGMSRS--NSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSY 1226 P Q P P + G A + + PG + + G S Sbjct: 944 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSG 1002 Query: 1227 EPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GP 1284 EP K + APG+ S +GP G +G PGL A P + G GP Sbjct: 1003 EPGK------QGAPGA----SGDRGPPGPVGP-------PGLTGPAGEPGREGSPGADGP 1045 Query: 1285 YDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFS 1344 R G G TGA P P SP P +Q + + G Sbjct: 1046 PGRDGAAGVKGDRG--ETGAVGAPGAPGPPG----SPGPAGPTGKQGDRGEAGAQG---- 1095 Query: 1345 TQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHE-GEMYSVPYSTGQGQPQQQ 1403 P G P+ R + G GP + E GE +G Q Sbjct: 1096 ----PMGPSGPAG------------ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1139 Query: 1404 QLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDR 1463 L P P P+ Q A+ P+ G P+ A GP P GR Sbjct: 1140 GL-PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP----PGPRGRSG 1194 Query: 1464 VSAPPGT--NAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG 1515 + P G N PP G I SA A G +G + + Y A++ + G Sbjct: 1195 ETGPAGPPGNPGPPGPPGPPGPGIDMSA-FAGLGPREKGPDPLQYMRADQAAGG 1247 Score = 32.7 bits (73), Expect = 4.2 Identities = 46/172 (26%), Positives = 59/172 (34%), Gaps = 32/172 (18%) Query: 1126 SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGD--LK-------------PPTPASTPH 1170 +Q + P PAG+ +QGPQ P+ E G+ LK PP P+ Sbjct: 1093 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQG 1152 Query: 1171 SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNP-GYQPSMNTSDMMGRMSYEPN 1229 + P P R + + DG++ P P G S G N Sbjct: 1153 ASGPAGPSGPRGPPGPVGPSGKDGANG--------IPGPIGPPGPRGRSGETGPAGPPGN 1204 Query: 1230 KDPYGSM-RKAPGSDPFMSSGQGPNGGMGDP--YSRAAGPGLGNVAMGPRQH 1278 P G PG D +G GP DP Y RA A G RQH Sbjct: 1205 PGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRA-----DQAAGGLRQH 1251 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 106 bits (264), Expect = 3e-22 Identities = 236/1002 (23%), Positives = 321/1002 (32%), Gaps = 140/1002 (13%) Query: 54 AGQESEGPAVGPPQPLGKELQDGAESNGGGGG--------GGAGSGGGPGAEPDLKNSNG 105 AG+ + GPP P G G G G G G G PG + + + Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 247 Query: 106 NAGPRPALNNNL------TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQP-YGRSP 158 N P P L T P G G +DG P A P P G P + +P Sbjct: 248 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP-----AGPPGPVGPAGGPGFPGAP 302 Query: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPN 218 A A G Q G + G G P AG N G P + ++ P Sbjct: 303 GAKGEAGPTGARGPEGAQGPRG----EPGTPGSPGP-AGASGNPGTDGIPGAKGSAGAPG 357 Query: 219 RSAYP-------PPAPAYALS--SPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQ 269 + P PP P A P+G T G A G + P A Sbjct: 358 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ------- 410 Query: 270 RFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGP 329 GA G G G +P + A G +G+PG D GP+ +GP Sbjct: 411 --GAPGPAGEEGKRGARGEPGGVGPIGP--PGERGAPGNRGFPGQDGLAGPKGAPGERGP 466 Query: 330 ADMASQCWG-------AAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381 + +A A +G + P G+ G G+P P P Sbjct: 467 SGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP--GPPGPQ 524 Query: 382 SPMDQMGKMR-PQPYG--GTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTPQRYPMTMQG 436 Q G M P P G G + ++G P P G PG+ G+ P Sbjct: 525 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL-RGLPGKDGETGAAGPPGPAGPAGE 583 Query: 437 RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496 R + G S Q +P G GP G G + ++ P P + P + Sbjct: 584 RGEQGAPGPSGFQGLP--GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 641 Query: 497 QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA 556 Q P+ P + P + P+ PP Q P + P + Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 701 Query: 557 QSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQ-------TAYSQQRFPPPQELSQDSFG 609 + P + L+ P P ++ A S P E + Sbjct: 702 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761 Query: 610 SQASSA--PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667 A A P G + + + Q + P G P G G P +G Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-----PSGAPGPQGP-TGVTGPK 815 Query: 668 SSQGEQSNPAQSPF-------SPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAV 719 ++G Q P + F P S PG GP P P G A+ SGP A Sbjct: 816 GARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-PGPSGKDGPKGARGDSGPPGRAGE 874 Query: 720 PGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGG 779 PG Q P PP + + P + S A+ P PQ + Q G P Q G Sbjct: 875 PGLQGPAGPPGEKGE----PGDDGPSGAE-------GPPGPQGLAGQRGIVGLPGQ-RGE 922 Query: 780 QIHTGMGSY-----QQNSMGSYGPQG--GQYGPQG--GYPRQPNYNALPNANYP-----S 825 + G+ +Q + G+ G +G G GP G G +P P A+ P + Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982 Query: 826 AGMAGGINPMGAGGQMHGQPGIP--PYGTLPPGRMSHASMGNR--PYGPNMANMPPQVGS 881 AG+ G GA G G PG P P P G+ P GP+ P Sbjct: 983 AGVKGDRGETGAVGAP-GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS----GPAGAR 1037 Query: 882 GMCPPPGGMNRKTQ-----ETAVAMHVAANSIQNRP-PGYPNMNQGGMMGTGP------- 928 G+ P G K + E + H +Q P P P+ +QG GP Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097 Query: 929 ----PYGQ-GINSMAGMINPQGPPYSMGGTMANNSAGMAASP 965 P G+ G N + G I P GP G T G P Sbjct: 1098 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139 Score = 102 bits (253), Expect = 6e-21 Identities = 210/834 (25%), Positives = 269/834 (32%), Gaps = 156/834 (18%) Query: 26 KAEQQQREE---AGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKEL------QDG 76 K EQ + E AG + A A E G+ A GP +GPP G QDG Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDG 453 Query: 77 AESNGGGGG--------GGAGSGGGPG--AEPDLKNSNGNAG-PRPALNNNLTEPPGGGG 125 G G G G+ G PG EP L + G G P A P G G Sbjct: 454 LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 513 Query: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL- 184 DG PP A P GF P G + A + G +PGL L Sbjct: 514 ---EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG-------EKGLPGAPGLRGLP 563 Query: 185 ----QSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 ++G G P AGP + G P P PP P G PG Sbjct: 564 GKDGETGAAGPPGP-AGPAGERGEQGAPGPSGFQGLPG----PPGPPGEGGKPGDQGVPG 618 Query: 241 S----GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPT 294 G G + P S + + G G GP A G G P P Sbjct: 619 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678 Query: 295 LNQL--------LTSPSSARGYQGYPGGDYSGGPQDGGAG-------KGPADMASQCWGA 339 L + + P RG G G + + G +DGG G GPA + Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG-KDGGRGLTGPIGPPGPAGANGEKGEV 737 Query: 340 AAAAAAAAAASGGAQ-QRSHHAPMSP----GSSGGGGQPLARTPQ-PSSPMDQMGKMRPQ 393 A +A + GA +R P P G G GQP A+ Q + G PQ Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797 Query: 394 -PYGGTNPYSQQQGPP--SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ 450 P G P QGP +GP+ G G P + P A +G Sbjct: 798 GPSGAPGP----QGPTGVTGPKGARGAQGPPGATGFPG---------AAGRVGPPGSNGN 844 Query: 451 IPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510 P G GPSG + G P P + +P Q P P + +P P Sbjct: 845 PGPPGPPGPSG--KDGPKGARGDSGP------PGRAGEPGLQGPAGPPGEKGEPGDDGPS 896 Query: 511 LQSSQPPYSQQ----------PSQPPHQQSPA-PYPSQQSTTQQHPQSQ----------P 549 + PP Q P Q + P P PS + Q P + P Sbjct: 897 -GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 955 Query: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609 P A P ++ P P A + + + A P P G Sbjct: 956 PGLTGPAGEPGREGSPGADGPPGRDGAAGV---KGDRGETGAVGAPGAPGPP-------G 1005 Query: 610 SQASSAPSMTSSKGGQEDMNLSL-QSRPSSLPDLSGSIDDLPMGTEG-ALSPGV----ST 663 S + P+ G+ + S P+ + G P G +G A PG Sbjct: 1006 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG--PRGDKGEAGEPGERGLKGH 1063 Query: 664 SGISSSQGEQSNP-------AQSPFSPHTSPHLPGIRGPS--------PSPVGSPASVAQ 708 G + QG P A P P PG GPS P P+G P + Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP--R 1121 Query: 709 SRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762 RSG PA PGN PP PP P ++ S+ A G ++ P QY Sbjct: 1122 GRSGETGPAGPPGNPGPPGPPGPPG-----PGIDMSAFA-GLGPREKGPDPLQY 1169 Score = 101 bits (252), Expect = 7e-21 Identities = 243/1002 (24%), Positives = 316/1002 (31%), Gaps = 229/1002 (22%) Query: 14 GNPPPP----PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPL 69 GNP PP PP + AGG A A+ G M+ G GP GPP P Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM--GPR-GPPGP- 145 Query: 70 GKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129 G G G G PG EP +G GPR PPG G Sbjct: 146 ------------AGAPGPQGFQGNPG-EPGEPGVSGPMGPRG--------PPGPPGKPGD 184 Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189 DG P A PP G G +PGL ++ G Sbjct: 185 DGEAGKPGKAGERGPPGPQG----------------------ARGFPGTPGLPGVKGHRG 222 Query: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249 Y G + G P + S P + P P L RG T +GAA A G+ Sbjct: 223 -----YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277 Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309 P G G GP GG P A + P+ ARG + Sbjct: 278 DGQP------------------GPAGPPGPVGPAGGPGFPGAPGAKGE--AGPTGARGPE 317 Query: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369 G G G P G+ GPA + A S GA PG +G Sbjct: 318 GAQGP--RGEPGTPGS-PGPAGASGN---PGTDGIPGAKGSAGA----------PGIAGA 361 Query: 370 GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP--YGSQTP 427 G P R P P P G T P GP+ G PG G Q P Sbjct: 362 PGFPGPRGP-------------PGPQGATGPL--------GPKGQTGEPGIAGFKGEQGP 400 Query: 428 QRYPMTMQGRAQSAMGGLSYTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486 + P G + Q P P G++G G +G+ P P ++ P + Sbjct: 401 KGEP------------GPAGPQGAPGPAGEEGKRG--ARGEPGGVGPIGP-PGERGAPGN 445 Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546 + P Q A P + P + P + + P +P P + T + Sbjct: 446 RGFPGQDGLAGP--KGAPGERGPSGLAGPKGANGDPGRP----GEPGLPGARGLTGRPGD 499 Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606 + P + +P + +P P P Q A QP FP P+ Sbjct: 500 AGPQGKVGPSGAPGEDGRPGPPGP-----QGARGQP----------GVMGFPGPKG---- 540 Query: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM--GTEGALSPGVSTS 664 A+ P KG LP G + LP G GA P + Sbjct: 541 -----ANGEPGKAGEKG---------------LPGAPG-LRGLPGKDGETGAAGPP-GPA 578 Query: 665 GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASV-AQSRSGPLSPAAVPGNQ 723 G + +GEQ P S F P P G P G P A GP PG + Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 638 Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783 P + + P + D P P + PG P + I Sbjct: 639 GSPG-----AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 693 Query: 784 GMGSYQQNSMGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGINPMG 836 G + +G GP+G G+ G +G G P N P G AG G Sbjct: 694 PKGD--RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP-GPAGSAGARG 750 Query: 837 AGGQMHGQPGIP-PYGTL-PPG-------RMSHASMGNR-------PYGPNMANMPPQVG 880 A G+ G+ G P P G PPG + G + P GP+ A PQ Sbjct: 751 APGE-RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP-GPQGP 808 Query: 881 SGMCPPPGGMNRKTQETAVAMHVAANSI-------QNRPPGYPNMN-----QGGMMGTGP 928 +G+ P G + A AA + PPG P + +G +GP Sbjct: 809 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP 868 Query: 929 PYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 P G G+ P GPP G + +G P GL Sbjct: 869 P---GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907 Score = 84.3 bits (207), Expect = 1e-15 Identities = 144/574 (25%), Positives = 176/574 (30%), Gaps = 67/574 (11%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAER---GEMKAAAGQESEGP-- 61 P+ L PP PP K +Q EAG ER GE + Q +GP Sbjct: 592 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651 Query: 62 ------------AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGP 109 A GP P G + G + G G AG G G D+ P Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGM-PGERGAAGIAGPKGDRGDVGEKGPEGAP 710 Query: 110 RPALNNNLT---EPPGGGGGGSSDGVGAPPHSAAAA------------LPPPAYGFGQPY 154 LT PPG G G PP A +A PP GF P Sbjct: 711 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770 Query: 155 GR--SPSAVAAAAAAVFHQQHG--GQQSPGLAALQSGGGG--GLEPYAGPQQNSHDHGFP 208 G P A A G G Q P A G G G + G Q GFP Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830 Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQ 268 P + P P P G + G A G PP + + Sbjct: 831 GAAGRVGPPGSNGNPGP------PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 884 Query: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPG-GDYSGGPQDGGAGK 327 G G GPS A G P P ++ P RG +G+PG SG P GA Sbjct: 885 GEKGEPGDDGPSGA-EGPPGPQGLAGQRGIVGLPGQ-RGERGFPGLPGPSGEPGKQGAPG 942 Query: 328 GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR-------TPQP 380 D G A ++ S A PG G G R P Sbjct: 943 ASGDRGPP--GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1000 Query: 381 SSPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438 P G P G + QGP PSGP G G P G + + R Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG-PQGPRGDKGEAGEPGERG 1059 Query: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPH-PQQQQPPYSQQPPSQTPHAQ 497 G + Q +P G GPS G QG + P P P + + P Sbjct: 1060 LKGHRGFTGLQGLP--GPPGPS--GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIP--G 1113 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP 531 P P+ + + + PP + P PP P Sbjct: 1114 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147 Score = 83.6 bits (205), Expect = 2e-15 Identities = 138/495 (27%), Positives = 158/495 (31%), Gaps = 117/495 (23%) Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75 PP P + +K E AG A A ERGE GPP P G Sbjct: 724 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE-------------TGPPGPAGFAGPP 770 Query: 76 GAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133 GA+ G G G AG G GA P + +G GP+ +T P G G G Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGAT 827 Query: 134 APPHSAAAALPPPAYGF-GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192 P +A PP + G G P PS A G PG A G GL Sbjct: 828 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-----RGDSGPPGRA-----GEPGL 877 Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAAAAGSK 250 + AGP + G A PP P L+ RG G PG Sbjct: 878 QGPAGPPGEKGEPGDDGPS--------GAEGPPGP-QGLAGQRGIVGLPGQRGERGFPGL 928 Query: 251 PPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTLNQLLTSPSSARGYQ 309 P PS G P A+G G P P P LT P+ G + Sbjct: 929 PGPSGEPGKQ----------------GAPGASGDRGPPGPVGPPG----LTGPAGEPGRE 968 Query: 310 GYPGGDYSGGPQDGGAG----------------------KGPA-DMASQCWGAAAAAAAA 346 G PG D G +DG AG GPA Q A A Sbjct: 969 GSPGADGPPG-RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027 Query: 347 AAASGGAQQRSHHAPMSP-GSSGGGGQP-------------LARTPQPSSPMDQMGKMRP 392 SG A R P P G G G+P L P P P G P Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087 Query: 393 Q-PYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ 449 P G P GP PSG +G PG P G P R +S G + Sbjct: 1088 AGPSGPRGP----PGPVGPSGKDGANGIPG-PIGPPGP---------RGRSGETGPAGPP 1133 Query: 450 QIP-PYGQQGPSGYG 463 P P G GP G G Sbjct: 1134 GNPGPPGPPGPPGPG 1148 Score = 64.3 bits (155), Expect = 1e-09 Identities = 155/667 (23%), Positives = 206/667 (30%), Gaps = 93/667 (13%) Query: 364 PGSSGGGGQP--LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQP 421 PG G G+P + P P G Q G ++G P GP+ G PG P Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP-GPRGRDGEPGTP 89 Query: 422 YGSQTPQ------------RYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTP 469 P + M G GG P G GP G P Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149 Query: 470 YYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQ 529 P Q P +P P P P +P + P PP Q Sbjct: 150 -----GPQGFQGNPGEPGEPGVSGPMG-PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203 Query: 530 SPAPYPSQQSTT-----QQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577 +P + +P ++ P + ++ SP + P P L + Sbjct: 204 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263 Query: 578 AYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPS 637 P + Q P + G AP G P Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323 Query: 638 SLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP 697 P GS P G G +PG T GI ++G P + +P PG RGP P Sbjct: 324 GEPGTPGSPG--PAGASG--NPG--TDGIPGAKGSAGAPGIAG-----APGFPGPRGP-P 371 Query: 698 SPVGSPASVA-QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRN 756 P G+ + + ++G A G Q P P + RG Sbjct: 372 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG----- 426 Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQG------- 807 +PG + P P G + G + G GP+G G+ GP G Sbjct: 427 ---------EPGG-VGPIGPPGERGAPGNRGFPGQD-GLAGPKGAPGERGPSGLAGPKGA 475 Query: 808 -GYPRQPNYNALPNANYPS-----AGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHA 861 G P +P LP A + AG G + P GA G+ G+PG P P G Sbjct: 476 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE-DGRPGPPG----PQGARGQP 530 Query: 862 SMGNRPYGPNMANMPPQVGS--GMCPPPG--GMNRKTQETAVA-----MHVAANSIQNRP 912 + P GP AN P G+ PG G+ K ET A A + Sbjct: 531 GVMGFP-GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589 Query: 913 PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972 PG P+ QG GPP G G+ G P +G G SP GL Sbjct: 590 PG-PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 648 Query: 973 VKLTPAT 979 + P T Sbjct: 649 PRGLPGT 655 Score = 64.3 bits (155), Expect = 1e-09 Identities = 88/351 (25%), Positives = 113/351 (32%), Gaps = 43/351 (12%) Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG-----GEAAAAAAAERGEMKAAAGQ 56 A +V P ++ PP PP K + R ++G GE A K G Sbjct: 833 AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 892 Query: 57 ESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSG-GGPGAEPDLKNSNGNAG----PRP 111 + A GPP P G Q G G G G GP EP + + G +G P P Sbjct: 893 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952 Query: 112 ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYG----FGQPYGRSPSAVAAAAAA 167 LT P G G S G PP AA G G P P A Sbjct: 953 VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012 Query: 168 VFHQ---QHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQ----YNSYYPNRS 220 Q G Q P + G G++ GP+ + + G P + + + + Sbjct: 1013 TGKQGDRGEAGAQGP-MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1071 Query: 221 AYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPS 280 PP P+ G SG A +G + PP S A G +G GP Sbjct: 1072 LPGPPGPS-------GDQGASGPAGPSGPRGPP---GPVGPSGKDGANGIPGPIGPPGPR 1121 Query: 281 AAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPAD 331 G T P G G PG G AG GP + Sbjct: 1122 GRSGETGP-----------AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPRE 1161 Score = 47.4 bits (111), Expect = 2e-04 Identities = 84/316 (26%), Positives = 102/316 (32%), Gaps = 37/316 (11%) Query: 690 PGIRGPS--PSPVGSPASVAQSRS----GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743 PG +GP+ P G + + G PGN PP PP P + Sbjct: 53 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP----PGLGG 108 Query: 744 SSIAQDRGYMQRNPQMPQYSSPQ-PGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-- 800 + AQ G Q Q P + PR P G G +Q N G G G Sbjct: 109 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNP-GEPGEPGVS 167 Query: 801 GQYGPQG--GYPRQPNYNALPNANYPS-AGMAGGINPMGAGGQMHGQPGIPPYGTLP--P 855 G GP+G G P +P + A P AG G P GA G G PG+P P Sbjct: 168 GPMGPRGPPGPPGKPGDDG--EAGKPGKAGERGPPGPQGARG-FPGTPGLPGVKGHRGYP 224 Query: 856 GRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAA--NSIQNRPP 913 G P + P + GS P G+ + T A A N Q P Sbjct: 225 GLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 284 Query: 914 GYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973 G P GP G G G GP + G A G +P G Sbjct: 285 GPPGP-------VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337 Query: 974 KLTPATKMNNKADGTP 989 P T DG P Sbjct: 338 SGNPGT------DGIP 347 Score = 39.3 bits (90), Expect = 0.045 Identities = 80/353 (22%), Positives = 110/353 (31%), Gaps = 50/353 (14%) Query: 1108 ERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAS 1167 E+GE PP +A ++ + + P G GP + E G+ A Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792 Query: 1168 TPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYE 1227 P Q P S + G Q G R + P PG + +G Sbjct: 793 APGPQGP-------SGAPGPQGP--TGVTGPKGARGAQGP-PGATGFPGAAGRVGPPGSN 842 Query: 1228 PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD--PYSRAAGPGLGNVAMGPRQHYPYGGPY 1285 N P G P S GP G GD P RA PGL A P + Sbjct: 843 GNPGPPG--------PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE-------- 886 Query: 1286 DRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFS 1344 + EPG GP G + G P P + +G P Q+ ++ + Sbjct: 887 ---KGEPGDDGPSG--AEGPPGPQGL-----AGQRGIVGLPGQRGERGFPGLPGPSGEPG 936 Query: 1345 TQGTPS-----GSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQ 1399 QG P G P P + + + G GPP + + TG Sbjct: 937 KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVG 996 Query: 1400 PQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQ 1452 PP P PA P+ +Q + G P + R GPQ Sbjct: 997 APGAPGPPGSPGPAG------PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ 1043 Score = 35.0 bits (79), Expect = 0.85 Identities = 85/364 (23%), Positives = 106/364 (29%), Gaps = 60/364 (16%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPP----LPGM-------- 1179 PP PAG +G Q S G PP P Q P PG+ Sbjct: 574 PPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERG 633 Query: 1180 --SRSNSVGIQDAFN----DGSDSTFQKRNSMTP--NPGYQPSMNTSDMMGRMSYEPNKD 1231 S G Q G+ T + + P PG Q M G Sbjct: 634 FPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG 693 Query: 1232 PYGSM----RKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDR 1287 P G K P P G+G G +G P A G V GP GP Sbjct: 694 PKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV--GP------PGPAGS 745 Query: 1288 VRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347 G G TG P P P + P + +Q + QG Sbjct: 746 AGARGAPGERG--ETGPPGPAGFAGPPGA-----DGQPGAKGEQGEAGQKGDAGAPGPQG 798 Query: 1348 TPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP 1407 PSG+P P T + + G GPP P + G+ P P Sbjct: 799 -PSGAPGPQGPTGV------TGPKGARGAQGPPGAT------GFPGAAGRVGPPGSNGNP 845 Query: 1408 AQPQPASQQQAAQPSPQQDVYNQYGNA-YPATATAATERRPAGGP-QNQFPFQFGRDRVS 1465 P P PS + G++ P A + PAG P + P G Sbjct: 846 GPPGPPG------PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 899 Query: 1466 APPG 1469 PPG Sbjct: 900 GPPG 903 Score = 34.3 bits (77), Expect = 1.4 Identities = 100/414 (24%), Positives = 132/414 (31%), Gaps = 60/414 (14%) Query: 1109 RGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAST 1168 RG PP A + ++ PP G+ GP P GD PP A Sbjct: 818 RGAQGPP---GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874 Query: 1169 PHSQIPPLPGMSRS--NSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSY 1226 P Q P P + G A + + PG + + G S Sbjct: 875 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSG 933 Query: 1227 EPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GP 1284 EP K + APG+ S +GP G +G PGL A P + G GP Sbjct: 934 EPGK------QGAPGA----SGDRGPPGPVGP-------PGLTGPAGEPGREGSPGADGP 976 Query: 1285 YDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFS 1344 R G G TGA P P SP P +Q + + G Sbjct: 977 PGRDGAAGVKGDRG--ETGAVGAPGAPGPPG----SPGPAGPTGKQGDRGEAGAQG---- 1026 Query: 1345 TQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHE-GEMYSVPYSTGQGQPQQQ 1403 P G P+ R + G GP + E GE +G Q Sbjct: 1027 ----PMGPSGPAG------------ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1070 Query: 1404 QLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDR 1463 L P P P+ Q A+ P+ G P+ A GP P GR Sbjct: 1071 GL-PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP----PGPRGRSG 1125 Query: 1464 VSAPPGT--NAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG 1515 + P G N PP G I SA A G +G + + Y A++ + G Sbjct: 1126 ETGPAGPPGNPGPPGPPGPPGPGIDMSA-FAGLGPREKGPDPLQYMRADQAAGG 1178 Score = 32.7 bits (73), Expect = 4.2 Identities = 46/172 (26%), Positives = 59/172 (34%), Gaps = 32/172 (18%) Query: 1126 SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGD--LK-------------PPTPASTPH 1170 +Q + P PAG+ +QGPQ P+ E G+ LK PP P+ Sbjct: 1024 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQG 1083 Query: 1171 SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNP-GYQPSMNTSDMMGRMSYEPN 1229 + P P R + + DG++ P P G S G N Sbjct: 1084 ASGPAGPSGPRGPPGPVGPSGKDGANG--------IPGPIGPPGPRGRSGETGPAGPPGN 1135 Query: 1230 KDPYGSM-RKAPGSDPFMSSGQGPNGGMGDP--YSRAAGPGLGNVAMGPRQH 1278 P G PG D +G GP DP Y RA A G RQH Sbjct: 1136 PGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRA-----DQAAGGLRQH 1182 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 105 bits (261), Expect = 7e-22 Identities = 139/480 (28%), Positives = 182/480 (37%), Gaps = 54/480 (11%) Query: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375 +GGP G AG G M + G + + A G S P PG+SG +A Sbjct: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143 Query: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430 TPQ + Q+ + Q + QQQ QQ Q Q+ Q++ Sbjct: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200 Query: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490 +Q + Q I + Q QQ Q Q QQQQ QQ Sbjct: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260 Query: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549 Q AQP QQ P QP P + P QQ H Q P P P Q Q P P Sbjct: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319 Query: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597 P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q Sbjct: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379 Query: 598 PP-----PQELSQDSFGSQASSAPSMTSSKGGQEDMNLS----LQSRPSSLPDLSGSIDD 648 P + L+Q +A P+ S + L Q SSLP LS Sbjct: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439 Query: 649 LPMGTEGALSPGVSTS---GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPAS 705 + T ++ P S G SSQ SN + P +P S LP PSP P SP + Sbjct: 440 QQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNVSSGP-APSPSSFLP---SPSPQPSQSPVT 494 Query: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765 +R+ PG P PS S+M P+ SS A+++ Y+ + Q+ +Y P Sbjct: 495 ---ARTPQNFSVPSPGPLNTPVNPS----SVMSPA--GSSQAEEQQYLDKLKQLSKYIEP 545 Score = 61.2 bits (147), Expect = 1e-08 Identities = 111/416 (26%), Positives = 140/416 (33%), Gaps = 67/416 (16%) Query: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486 P ++ G + G+ + P G G GQ + Q P P+S Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140 Query: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542 S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q Sbjct: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197 Query: 543 QHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602 Q Q+ Q Q Q QQQ QQ Q Q Q QQ Q+ A Q + Q+ Sbjct: 198 QQFQAVVQQQQ-QLQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253 Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662 Q QA A Q+ Q+ P L + + P P Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP-------PPQPQ 306 Query: 663 TSGISSSQGEQSNPAQSPFSP-------------HTSPHLPGIRGPS--PSPVGSPASVA 707 ++ +Q Q P QS P +T P L +R P P P Sbjct: 307 QPPVAQNQPSQL-PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365 Query: 708 QSRSGPLSPAA---VPGNQMPPR-------------PPSGQSDSIMHPSMNQSSIAQDRG 751 Q + + AA PG QM PP+ +I PS SSI R Sbjct: 366 QQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAI--PS---SSIPLGRQ 420 Query: 752 YMQRNPQ--MPQYSSPQPGSALS-------PRQPSGGQIHTGMGSYQQNSMGSYGP 798 M + Q +P SSP PG + P QPS G S Q NS S GP Sbjct: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP---QPGQPSSQPNSNVSSGP 473 Score = 58.9 bits (141), Expect = 5e-08 Identities = 102/400 (25%), Positives = 138/400 (34%), Gaps = 74/400 (18%) Query: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEG 1386 QQQQQQQQ+ + Q Q P P P + QQ QQ + + PP + Sbjct: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQ---HHQPPPQ---- 304 Query: 1387 EMYSVPYSTGQGQPQQQQLPP-AQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATER 1445 P Q Q QLPP +Q QP Q AQ P Q +Y Q + + Sbjct: 305 -----PQQPPVAQNQPSQLPPQSQTQPLVSQ--AQALPGQMLYTQPPLKF--VRAPMVVQ 355 Query: 1446 RPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMT 1505 +P PQ Q T Q QM+ +Q E QG M Sbjct: 356 QPPVQPQVQ------------QQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPP 403 Query: 1506 YNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMT 1565 + + S P G M Q + S PS G +Q S P PP Sbjct: 404 TTAVSAIPSSSIPLG--------RQPMAQVSQSSLPMLSSPSPG-QQVQTPQSMPPPPQP 454 Query: 1566 RPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTS--PSKSPFLHSGMKMQKAGPPVPAS 1623 P P PS Q + S PAP P S PS+SP A P S Sbjct: 455 SPQPGQ----PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV--------TARTPQNFS 502 Query: 1624 HIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAE 1683 +P P+ P+ + P GS +A + + + K I E R M++ Sbjct: 503 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYI---EPLRRMIN-------- 551 Query: 1684 STWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRC 1723 D N +LS++ LL++L + +RC Sbjct: 552 -----------KIDKNEDRKKDLSKMKSLLDILTDPSKRC 580 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 105 bits (261), Expect = 7e-22 Identities = 198/833 (23%), Positives = 272/833 (32%), Gaps = 178/833 (21%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66 PA+A PPPPPP+ A Q G + A G+ S P G P Sbjct: 295 PASAQP---PPPPPPAH---ALQHYLSCGGSYPSMGHRANLACSPLGGGEPS--PGAGEP 346 Query: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGG 126 G GA + G G + GG GA G G RP + + + GG G Sbjct: 347 SKAGPS---GATAGASGRATGPEAAGGGGA------GGGGGGYRPIIQSPGYKTGKGGYG 397 Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186 ++ G PP + A P G P + A+ A Q + Q GL Sbjct: 398 AAAGGATRPPPPRSTATPK-CQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLL---- 452 Query: 187 GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA 246 GPQ G Q S P+ S PP P+ Sbjct: 453 ----------GPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPS------------------ 484 Query: 247 AGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSAR 306 PPP + S S Q +G G P A PTA+P+L+ + Sbjct: 485 --GPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALS 542 Query: 307 GYQGYPGGDYSGG----------------PQDG---GAGKGPAD-------MASQCWGAA 340 G+ G G GG P G G G A +AS + A Sbjct: 543 GHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAP 602 Query: 341 AAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTP----------QPSSPMDQMGKM 390 A + AA +GG + + + + +G GG P RT Q SP G Sbjct: 603 PGAGSYAAGAGGYKGKGDGSEL---LAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGAD 659 Query: 391 RPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPY--GSQTPQRYPMTMQGRAQSA------- 441 G S+ G G G PG PY + PQRY + R ++ Sbjct: 660 GLVGEDGAADASKGLGGSGG---AGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATA 716 Query: 442 -----MGGLSYTQQIPPYGQQGPSG-------YGQQG-QTPYYNQQSPHPQQQQPPYSQQ 488 +G L ++ P G + P G YG + + Q+SP P PP + Q Sbjct: 717 ALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPP----PPPTAQ 772 Query: 489 PPSQTPHA---QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPS-------QQ 538 TPH + P PP PP PS H SP+P S + Sbjct: 773 STQPTPHGLLLEAGGPDLPLVLPP------PPPQLLPSVLSHAPSPSPSASKVGVHLLEP 826 Query: 539 STTQQHPQSQPPYSQPQAQSPYQQQ--------QPQQPAPSTLSQQAAYPQPQSQ----- 585 +T PQ PP P P Q + +P P+P +++ P Q Sbjct: 827 ATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGA 886 Query: 586 -QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG 644 + A PP +D G+ S PS +K + S+ S L D Sbjct: 887 LEPLPPAPGDTGVGPPNSEGKDPAGAYRS--PSPQGTKAPRFVPLTSICFPDSLLQDEER 944 Query: 645 SIDDLPMGTE---GALSPGVSTSGISSSQGE--------QSNPAQSPFSPH-------TS 686 S P E G + +G +G+ PA P+ P+ Sbjct: 945 SF--FPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAG 1002 Query: 687 PHLPGIRGPSPSPVGSPASVAQS-----RSGPLSPAAVPGNQMPPRPPSGQSD 734 P PG+ P P++V +SGP AA P PP PP+ S+ Sbjct: 1003 PETPGLGLDPNKPPELPSTVNAEPLGLIQSGP-HQAAPPPPPPPPPPPAPASE 1054 Score = 83.2 bits (204), Expect = 3e-15 Identities = 236/1048 (22%), Positives = 323/1048 (30%), Gaps = 282/1048 (26%) Query: 34 EAGGEAAAAAAAERGEMKAAAGQESEGPAVGP------PQPLGKELQDGAESNGGG---- 83 + G A +A + M + ES GP GP Q Q + G Sbjct: 73 DTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFI 132 Query: 84 GGGGAGSGGGPGAE---------------------------PDLKNSNGNAGPRPALNNN 116 G GS P + P +NG P L+ Sbjct: 133 SGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLK 192 Query: 117 LTEPP-----------GGGGGGSSDGVG---APPHSAAAA-LPPPAYGFGQPYGRSPSAV 161 ++ P GGG G+G PP+ PPP + S+ Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252 Query: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEP-YAGPQQNSHDHGFPNHQYNSYYPNRS 220 AAAAAA Q SP L G P A P+Q++ Y S Sbjct: 253 AAAAAA-------EQSSPQLYNFSGAAPGPPPPERALPRQDT--------VIKHYQRPAS 297 Query: 221 AY--PPPAPAYALS--------------------SPRGG---TPGSGAAAAAGSKPPPSS 255 A PPP PA+AL SP GG +PG+G + AG PS Sbjct: 298 AQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG----PSG 353 Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGD 315 + + +S ++ + A GGGG GGG ++ SP G GY G Sbjct: 354 ATAGASGRATGPE----AAGGGGAGGGGGG---------YRPIIQSPGYKTGKGGY--GA 398 Query: 316 YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA 375 +GG + A Q G AAA A AS G+ G GGQ Sbjct: 399 AAGGATRPPPPRSTATPKCQSLGGPAAAYATGKAS--------------GAGGAGGQAY- 443 Query: 376 RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQ 435 SP G + PQ YG Q Q P G P P G P T Q Sbjct: 444 ------SPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGL--ATCQ 495 Query: 436 GRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQT-----PYYNQQSPHPQQQQPPYSQQPP 490 + + G Y Q PY GP+ + Q T Y SP + Sbjct: 496 SYSPDQLQGQLYGVQGEPY--PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSL 553 Query: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPP 550 A PS+ +P PP + +PP P P S + P Sbjct: 554 GGGGEASPSHIIRPLQSPP--ATGRPPGVGSPGAPGKYLSSV-------------LASAP 598 Query: 551 YSQPQAQSPYQQQQPQQPAPSTLSQQAAYP-QPQSQQSQQTAYSQQRF----PPPQELSQ 605 + P Y S+ A P P +++++ + Q PP+ Sbjct: 599 FLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGA 658 Query: 606 DSF--------------GSQASSAPSMTSSKGGQED-----------MNLSLQSRPSSLP 640 D GS + P T + +ED + SL ++ Sbjct: 659 DGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAAL 718 Query: 641 DLS-GSIDDLPMGTE--GALSPGVSTSGISSSQG--------EQSNPAQSPFSPHTSPHL 689 +L G + + G E G G++TS + G ++S P P + T P Sbjct: 719 ELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTP 778 Query: 690 PGI--------------------------RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ 723 G+ PSPSP S V L PA G Sbjct: 779 HGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL-----LEPATRDGAP 833 Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ---MPQYSSPQPGS------ALSPR 774 PP PP + + + + G P P+ S PG+ AL P Sbjct: 834 QPPPPPPPPPPPM---PLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPL 890 Query: 775 QPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSA-------- 826 P+ G TG+G NS G P G P + P + L + +P + Sbjct: 891 PPAPGD--TGVG--PPNSEGK-DPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERS 945 Query: 827 -----------------GMAGGI----NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGN 865 G AG +P G G P PYG PGR S G Sbjct: 946 FFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRAS----GA 1001 Query: 866 RPYGPNMA---NMPPQVGSGMCPPPGGM 890 P P + N PP++ S + P G+ Sbjct: 1002 GPETPGLGLDPNKPPELPSTVNAEPLGL 1029 Score = 61.2 bits (147), Expect = 1e-08 Identities = 116/477 (24%), Positives = 152/477 (31%), Gaps = 96/477 (20%) Query: 527 HQQS-PAPYPSQQSTTQQHP---------------QSQPPYSQPQAQSPYQQQQPQQPAP 570 H+Q+ AP+P Q T HP + P S S + + P QP P Sbjct: 46 HRQAYAAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGP-QPGP 104 Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630 S S + + P Q + T P P EL +S+ PS ++ Q Sbjct: 105 SASSLLSQFRSPSWQTAMHT-------PGPTELFISGALPGSSTFPSSSALSAYQHP--A 155 Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690 S SRP +P S S+ D P S PA SPH HL Sbjct: 156 SFGSRPFPVPS-SLSLQDPPF----------------------SPPANGLLSPHDVLHLK 192 Query: 691 GIRGPS-PSPVGSPASVAQSRSGP--LSPAAVPGNQM-PPRPPSGQSDSIMHPSMNQSSI 746 + P+ PS +G GP L PA P + PP PP ++ SS Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252 Query: 747 AQDRGYMQRNPQMPQYSSPQPG----------------------SALSPRQP-------- 776 A Q +PQ+ +S PG SA P P Sbjct: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQH 312 Query: 777 --SGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINP 834 S G + MG + G GG+ P G +P+ A ++G A G Sbjct: 313 YLSCGGSYPSMGHRANLACSPLG--GGEPSPGAG---EPSKAGPSGATAGASGRATGPEA 367 Query: 835 MGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKT 894 G GG G G P P + G G P + C GG Sbjct: 368 AGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGG-PAAA 426 Query: 895 QETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMG 951 T A Q PG P G++G YGQG + P YS G Sbjct: 427 YATGKASGAGGAGGQAYSPGQPQ----GLLGP-QAYGQGFGGGQAQDLSKAPSYSGG 478 Score = 47.4 bits (111), Expect = 2e-04 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 10/93 (10%) Query: 482 QPPYSQQPPSQTPHAQPSYQQQPQSQP----PQLQSSQPPYSQQPSQPPHQQSPAPYPSQ 537 +PP ++ P TP P+ Q QP P P L S P + PS PP P P P Sbjct: 1449 EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPA 1508 Query: 538 QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570 + P PP + P A P ++P P+P Sbjct: 1509 MPSP---PPPPPPAAAPLAAPP---EEPAAPSP 1535 Score = 45.1 bits (105), Expect = 8e-04 Identities = 138/670 (20%), Positives = 218/670 (32%), Gaps = 123/670 (18%) Query: 1074 RELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADS-----KKSQP 1128 R L T N+ SSSAA++ +Q LY F G PP D+ ++ Sbjct: 239 RHLPTQFNLLASSSAAAAAAEQSSPQLYNFS-GAAPGPPPPERALPRQDTVIKHYQRPAS 297 Query: 1129 KIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLK-------PPTPASTPHSQIPPLPGMSR 1181 PP P + ++Q + + SM +L P+P + S+ P + Sbjct: 298 AQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAG 357 Query: 1182 SN--SVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSM-NTSDMMGRMSYEPNKDPYGSMRK 1238 ++ + G + A G+ + +PGY+ G + P + + Sbjct: 358 ASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKC 417 Query: 1239 APGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEG 1298 P + G G G +A PG +GP+ YG + + + + Sbjct: 418 QSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQ---AYGQGFGGGQAQ-DLSKAP 473 Query: 1299 NMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQ---QQRHDSYGNQFSTQGTPSGSPFP 1355 + S G PQP P P G+ + Y P Q Q Q Q G +QG P+ SP Sbjct: 474 SYSGGPPQPPSGP--PPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASP-- 529 Query: 1356 SQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGE------MYSVPYSTGQGQPQQQQLPPAQ 1409 + Y G +GP + GE + + G+P P A Sbjct: 530 ---SLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAP 586 Query: 1410 PQPASQQQAAQP---SPQQDVYNQYGNAYPATATAATERRPAGGP------QNQFPFQF- 1459 + S A+ P P Y Y + GGP +F Q Sbjct: 587 GKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHL 646 Query: 1460 -----------------------------GRDRVSAPPGTN---AQQNMPPQMMGGPIQA 1487 G PPGT A+++ + I+ Sbjct: 647 LQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRT 706 Query: 1488 SAEVAQQGT--MWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSW 1545 SA + + T + G + + G P+G A ++H A G++ Sbjct: 707 SASLDEGATAALELGLGRLKEKKKGPERGGETPEGLA-------TSVVHYGAGAKELGAF 759 Query: 1546 ---------PSHGTRQP-PYG----PSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPL 1591 P+ + QP P+G P P+ PP PPP + +P V S AP Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPP-----PPPQL---LPSVLSHAPS 811 Query: 1592 PRPMENRTSPS-KSPFLHSGMKMQKAGPPVP------------ASH-IAPAPVQPPMIRR 1637 P P ++ P G PP P SH + PA P + Sbjct: 812 PSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE 871 Query: 1638 DITFPPGSVE 1647 + PPG+++ Sbjct: 872 ESLDPPGAMQ 881 Score = 43.9 bits (102), Expect = 0.002 Identities = 67/248 (27%), Positives = 85/248 (34%), Gaps = 53/248 (21%) Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75 PPPPPP + + G E AA + R E ES P G Q L L+ Sbjct: 838 PPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE-------ESLDPP-GAMQELLGALEP 889 Query: 76 GAESNGGGGGGGAGSGG-GPGAEPDLKNSNGNAGPRPALNNNLTEPPG------------ 122 + G G G S G P + G PR ++ P Sbjct: 890 LPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPT 949 Query: 123 -----GGGGGSSDGVGAPPHSA----AAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173 GGG G PP A A PPP PYG P A+ A Sbjct: 950 MEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYG--PYCPGRASGA------ 1001 Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA----Y 229 G ++PGL GL+P P+ S + P S P+++A PPP P Sbjct: 1002 -GPETPGL---------GLDPNKPPELPSTVNAEPLGLIQSG-PHQAAPPPPPPPPPPPA 1050 Query: 230 ALSSPRGG 237 S P+GG Sbjct: 1051 PASEPKGG 1058 Score = 43.9 bits (102), Expect = 0.002 Identities = 32/105 (30%), Positives = 37/105 (35%), Gaps = 13/105 (12%) Query: 1547 SHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPF 1606 S+GT +PP P P P QPPP P + SP PL P + P P Sbjct: 1444 SNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLP- 1502 Query: 1607 LHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQP 1651 PP PA P P PP + PP A P Sbjct: 1503 ----------PPPPPAMPSPPPP--PPPAAAPLAAPPEEPAAPSP 1535 Score = 43.5 bits (101), Expect = 0.002 Identities = 120/547 (21%), Positives = 183/547 (33%), Gaps = 113/547 (20%) Query: 1142 QGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPP-------LPGMSRSNSVGIQDAFNDG 1194 +GPQ S SS +++ + P+ + H+ P LPG S S A+ Sbjct: 98 RGPQPGPSASSLLSQ---FRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQH- 153 Query: 1195 SDSTFQKRNSMTPN------PGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSS 1248 ++F R P+ P + P N G +S P+ + P P + S Sbjct: 154 -PASFGSRPFPVPSSLSLQDPPFSPPAN-----GLLS------PHDVLHLKPSQAPTVPS 201 Query: 1249 GQGPNGGMGDPYSRAAGPG-LGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNM--STGA 1304 G + R AG G LG +GP Q PY GP D + + N+ S+ A Sbjct: 202 SLG--------FERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSA 253 Query: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQ 1364 S+P +S + P ++ R D+ + + P P + Sbjct: 254 AAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHAL--- 310 Query: 1365 QQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424 Q+Y G+Y P+ H + P G+ P + A P A+ Sbjct: 311 --QHYLS-CGGSY--PSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA--------- 356 Query: 1425 QDVYNQYGNAYPATATAATERRPAGG------PQNQFP-FQFGRDRVSAPPGTNAQQNMP 1477 G + AT A AGG P Q P ++ G+ A G A + P Sbjct: 357 -------GASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG-GATRPPP 408 Query: 1478 P--------QMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRT 1529 P Q +GGP A YA +++G+ G + + Sbjct: 409 PRSTATPKCQSLGGPAAA--------------------YATGKASGAGGAGGQAYSPGQP 448 Query: 1530 DEMLHTDQRANHEGSWPSHG-TRQPPYGPSAPVPPMTRPPPS----NYQPPPSMQNHIPQ 1584 +L G + ++ P Y P PP PPP P +Q + Sbjct: 449 QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYG 508 Query: 1585 VSSPAPLPRP-MENRTSPSKSPFL-----HSGMKMQKAGPPVPASHIAPAPVQPPMIRRD 1638 V P P P ++ P+ SP L HS G P+S P I R Sbjct: 509 VQG-EPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRP 567 Query: 1639 ITFPPGS 1645 + PP + Sbjct: 568 LQSPPAT 574 Score = 43.1 bits (100), Expect = 0.003 Identities = 48/186 (25%), Positives = 62/186 (33%), Gaps = 27/186 (14%) Query: 381 SSPMDQMGKMRPQPYGGTNPYSQQQGPP-SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ 439 S D + K R ++ S PP +GP+ G P P + G Sbjct: 1382 SDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS 1441 Query: 440 SAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499 + G PP ++ P P +P PQ Q PP P P P Sbjct: 1442 ANSNGTPE----PPLLEEKP---------PPTPPPAPTPQPQPPPPPPPPQPALPSPPPL 1488 Query: 500 YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559 P S PP PP P PP SP P P + P + PP +P A SP Sbjct: 1489 VAPTPSSPPP------PPL--PPPPPPAMPSPPPPPPPAAA----PLAAPP-EEPAAPSP 1535 Query: 560 YQQQQP 565 + P Sbjct: 1536 EDPELP 1541 Score = 42.4 bits (98), Expect = 0.005 Identities = 33/108 (30%), Positives = 39/108 (36%), Gaps = 12/108 (11%) Query: 1553 PPYGPSAPVPPMTRPPP--------SNYQP-PPSMQNHIPQVSSPAPLPRPMENRTSPSK 1603 PP P+A VP PPP SN P PP ++ P PAP P+P P Sbjct: 1422 PPLAPAAAVPG---PPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPP 1478 Query: 1604 SPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQP 1651 P L S + P P P P P M PP + P Sbjct: 1479 QPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526 Score = 40.0 bits (92), Expect = 0.026 Identities = 28/104 (26%), Positives = 36/104 (34%), Gaps = 11/104 (10%) Query: 498 PSYQQQPQSQPPQLQSSQPPY-----SQQPSQPPHQQSPAP-YPSQQSTTQQHPQSQPPY 551 PS +PP L+ PP + QP PP P P PS P S PP Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499 Query: 552 SQPQAQSPYQQQQPQQPAPSTL-----SQQAAYPQPQSQQSQQT 590 P P P P P+ ++ A P P+ + T Sbjct: 1500 PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT 1543 Score = 39.7 bits (91), Expect = 0.034 Identities = 54/236 (22%), Positives = 81/236 (34%), Gaps = 33/236 (13%) Query: 549 PPYSQPQAQSP------YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602 PP S P++ P Q Q P PA A+ + ++ ++ P P + Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCK 1364 Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662 + + PS +S + N LQ S+ ++DD P+ Sbjct: 1365 RLDEELKRNLETLPSFSSDEEDSVAKNRDLQE---SISSAISALDDPPLA---------G 1412 Query: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSP--AAVP 720 S+ G PA + P P LPG+ PS + G+P P +P A P Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGP---PPLPGL--PSANSNGTPEPPLLEEKPPPTPPPAPTP 1467 Query: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQP 776 Q PP PP Q P + + +P P P P + SP P Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPT--------PSSPPPPPLPPPPPPAMPSPPPP 1515 Score = 39.7 bits (91), Expect = 0.034 Identities = 36/138 (26%), Positives = 46/138 (33%), Gaps = 14/138 (10%) Query: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH-QQSPAPYPSQQSTT 541 PP + + TP P PP L S +PP ++ P P P T Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467 Query: 542 QQHPQSQPPYSQPQAQSP--YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPP 599 Q P PP QP SP P P P L P P + S PP Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP----PPPPAMPSPPP-------PP 1516 Query: 600 PQELSQDSFGSQASSAPS 617 P + + + +APS Sbjct: 1517 PPAAAPLAAPPEEPAAPS 1534 Score = 37.4 bits (85), Expect = 0.17 Identities = 231/1070 (21%), Positives = 339/1070 (31%), Gaps = 167/1070 (15%) Query: 591 AYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650 A+ Q+ PPP +Q + P + G D+ L L P L L + P Sbjct: 758 AFLQKSPPPPPPTAQST-----QPTPHGLLLEAGGPDLPLVLPPPPPQL--LPSVLSHAP 810 Query: 651 MGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSP-----HLP--GIRGPSPSPVGSP 703 + A GV ++ G P P P P HL G+ +PSP P Sbjct: 811 SPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRP 870 Query: 704 ASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ----- 758 +S P + + G + P PP+ + P+ A Y +PQ Sbjct: 871 E---ESLDPPGAMQELLG-ALEPLPPAPGDTGVGPPNSEGKDPAG--AYRSPSPQGTKAP 924 Query: 759 --MPQYSSPQPGSALSPRQPSGGQIHTGM-GSYQQNSMGSYGPQGGQYGPQGGYPRQPNY 815 +P S P S L + S M G + G GP + P+ G P Sbjct: 925 RFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984 Query: 816 NALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANM 875 A G A G P G + P PP P ++ +G GP+ A Sbjct: 985 PAYDPYGPYCPGRASGAGPETPGLGL--DPNKPPE---LPSTVNAEPLGLIQSGPHQAAP 1039 Query: 876 P-----PQVGSGMCPPPGGMNR----KTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926 P P + P GG+ T+ + + + ++ R P + + Sbjct: 1040 PPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKK------ 1093 Query: 927 GPPYGQGINSMAGMINPQGP------PYSMGGTMANNSAGMAASPEMMGLGDVKLTPATK 980 Y Q A P P + +++ + A SP LGD+ P Sbjct: 1094 --LYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSP----LGDIDFCPP-- 1145 Query: 981 MNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTN 1040 N DG + K K+ + G P R L + Sbjct: 1146 -NPGPDGPRRRGRKPTKAKRDGPPRPR--------GRPRI-----RPLEVPTTAGPASAS 1191 Query: 1041 LPAVG-RKPLDLYRLYVSVKEIGGLTQVNKNK----KWRELATNLNVGTSSSAA------ 1089 P G +KP R E G T++ K K +GTSS A Sbjct: 1192 TPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDH 1251 Query: 1090 ----SSLKKQYIQCLYAFECKIERGEDPPPDI---FAAA--DSKKSQPKIQPPSPAGSGS 1140 SSL ++ I E KI+ E+ P++ F A+ D KS + P AG Sbjct: 1252 NSLDSSLTREKI------EAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTP 1305 Query: 1141 MQGPQTPQSTSSSM-AEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTF 1199 P P+S S+ A G +PP + PH G+ + + G S Sbjct: 1306 PLSP--PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPC 1363 Query: 1200 QKRNS-MTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGS--DPFMSSGQGPNGGM 1256 ++ + + N PS ++ + S N+D S+ A + DP P G Sbjct: 1364 KRLDEELKRNLETLPSFSSDE---EDSVAKNRDLQESISSAISALDDP-------PLAGP 1413 Query: 1257 GDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDS 1316 D S GP L A P GP PG+ P N S G P+P L+ P Sbjct: 1414 KDT-STPDGPPLAPAAAVP-------GPPPL----PGL-PSAN-SNGTPEPPLLEEKP-- 1457 Query: 1317 GMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS-GSPFPSQQTTMYQQQQQNYKRPMDG 1375 P PP Q Q Q + P +P PS P Sbjct: 1458 ----PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513 Query: 1376 TYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQ--AAQPSPQQDVYNQYGN 1433 PPA + + P P+ +LP +P +++Q AA + + G Sbjct: 1514 PPPPPAA---APLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGG 1570 Query: 1434 AYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQ----QNMPPQMMGGPIQASA 1489 R P + Q GR+ PP Q Q P++ G Q A Sbjct: 1571 EGIFRERDEFVIRAEDIPSLKLALQTGRE---PPPIWRVQKALLQKFTPEIKDGQRQFCA 1627 Query: 1490 EVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHG 1549 G +N Y VN+ D + ++ H P Sbjct: 1628 TSNYLGYFGDAKNRYQRLYVK-----------FLENVNKKDYVRVCARKPWHRPPVPVRR 1676 Query: 1550 TRQPPY-----GPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRP 1594 + Q G SAP P PPP P + P+ + +P P Sbjct: 1677 SGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEP 1726 Score = 34.3 bits (77), Expect = 1.4 Identities = 29/108 (26%), Positives = 42/108 (38%), Gaps = 25/108 (23%) Query: 16 PPPPPPSELKKAEQQQREEA--------GGEAAAAAAAERGEMKAAAGQESEG------- 60 P P PS L+ E+++ +E GE A + R E A GQ + Sbjct: 1727 PAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARP 1786 Query: 61 ---PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNG 105 A PP+ K L++ GG GG PG+ D ++S G Sbjct: 1787 TKVKAEPPPKKRKKWLKEA-------GGNATAGGGPPGSSSDSESSPG 1827 Score = 32.7 bits (73), Expect = 4.2 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 1557 PSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKA 1616 P P PP PPP Q +++H + ++P+P RP E+ P L ++ Sbjct: 833 PQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPL-- 890 Query: 1617 GPPVP 1621 PP P Sbjct: 891 -PPAP 894 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 103 bits (258), Expect = 1e-21 Identities = 257/1057 (24%), Positives = 340/1057 (32%), Gaps = 181/1057 (17%) Query: 55 GQESEGPAVGP---PQPLGKELQDGAESNGG--GGGGGAGSGGGPG-----------AEP 98 G++ E A+GP P G++ Q G + +GG G G G G PG +P Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDP 437 Query: 99 DLKNSNGNAG-PRPALNNNLTEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQP 153 G AG P P L PPG G G+ G PP ++ +P G+P Sbjct: 438 GFVGPEGLAGEPGPP---GLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKP 494 Query: 154 YGR--------SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP---QQNS 202 G+ P V F G PG G G P G Q Sbjct: 495 -GKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPG----PKGEPGDPVPARGDPGIQGIK 549 Query: 203 HDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG-SGAAAAAGSKPPPSSSASASS 261 + G P +S + + + SP G PG G A G K + A Sbjct: 550 GEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGP 609 Query: 262 SSSSFAQQRFGAMGGGGPSAAGGGTPQP-TATPTLNQL---------LTSPSSARGYQGY 311 + S G G GP+ G +P P L+ L L PS +G G Sbjct: 610 AGSP------GPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP 663 Query: 312 PG-------------------GDYSGGPQDGG----------AGKGPADMASQCWGAAAA 342 PG GD +G P D G +G+ + G Sbjct: 664 PGFGLPGKQGKAGERGLKGQKGD-AGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGD 722 Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSG-GGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPY 401 A + G P PG G G + + R +P P G Q G Sbjct: 723 GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQP----GLPGVQGPPGLKGV 778 Query: 402 SQQQGPP----SGPQQGHGYPGQP--YGSQTPQRYP-MTMQGRAQSAMGGLSYTQQIPPY 454 + GPP GPQ G PG P G P+ P T + AQ + G T + P Sbjct: 779 QGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPP 838 Query: 455 GQ--QGPSGY-GQQGQTPYY---NQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQP 508 G GP G GQQGQT ++ P ++ +P P + P + Sbjct: 839 GASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP----SQGDLIFSGMPGAPG 894 Query: 509 PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP-QSQPPYSQPQAQSPYQQQQPQQ 567 + SS P Q P P P P Q + QP + P +Q + Sbjct: 895 LWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKS 954 Query: 568 PAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQ-----------DSFGSQASSAP 616 + Q A+P ++ ++ P +Q ++ G + P Sbjct: 955 ICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDP 1014 Query: 617 SMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL----PMGTEGAL-SPGV-------STS 664 S G L Q P + GS P G GA+ SPG+ + Sbjct: 1015 GCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLT 1074 Query: 665 GISSSQGEQSNPAQSPFSPHTS-PHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ 723 G++ +GE P Q + T P LPGI+G GS + GP PG++ Sbjct: 1075 GLTGDKGEPGPPGQPGYPGATGPPGLPGIKG-ERGYTGSAGE--KGEPGP------PGSE 1125 Query: 724 MPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQ--PGSALSPRQPSGGQI 781 P PP S D+G+ Q P P P PG SP P G Q Sbjct: 1126 GLPGPPGPAGPRGERGPQGNSGEKGDQGF-QGQPGFPGPPGPPGFPGKVGSP-GPPGPQA 1183 Query: 782 HTGMGSYQQNS--MGSYGPQG--GQYGPQG-----GYPRQPNYNALPNANYPSAGMAGGI 832 G + S GS GP G G GP G G +P P AG G + Sbjct: 1184 EKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPG----PAGPPGLM 1239 Query: 833 NPMGAGGQMHGQPGIP-PYGTL----PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887 P G G+ G PG+P P G PPG P P G P P Sbjct: 1240 GPPGFKGKT-GHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGP 1298 Query: 888 GGMNRKTQETAVAMH----------VAANSIQNRPPGYPNM-----NQGGMMGTGPPYGQ 932 G +AV + +A Q PPG+P G GPP Q Sbjct: 1299 PGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQ 1358 Query: 933 GINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMG 969 G G G G AGM P G Sbjct: 1359 GFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395 Score = 87.4 bits (215), Expect = 1e-16 Identities = 245/1045 (23%), Positives = 333/1045 (31%), Gaps = 181/1045 (17%) Query: 10 ASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPL 69 A S G P P P+ +K A+ + E A + + G+++ A G G P P Sbjct: 610 AGSPGPPGPVGPAGIKGAKGEPCEPC----PALSNLQDGDVRVVALPGPSGEK-GEPGPP 664 Query: 70 GKELQDGAESNGGGGG--GGAGSGGGPGAEPDLKNSNGNAGPRPALNNNL-TEPPGGGGG 126 G L G + G G G G G PG +P + G RP L+ + P G G Sbjct: 665 GFGLP-GKQGKAGERGLKGQKGDAGNPG-DPGTPGTTG----RPGLSGEPGVQGPAGPKG 718 Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRS---PSAVAAAAAAVFHQQHGGQQSPGLAA 183 DG A P S + A GQP + P V G Q PGL Sbjct: 719 EKGDGCTACP-SLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKG 777 Query: 184 LQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGA 243 +Q G GPQ G P Q P P + +G G Sbjct: 778 VQGEPGPPGRGVQGPQGEPGAPGLPGIQ---------GLPGPRGPPGPTGEKGAQGSPGV 828 Query: 244 AAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTS 301 A G PP +S S Q + G G G G G P + P+ L+ S Sbjct: 829 KGATGPVGPPGASVSGPPGRDG-QQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFS 887 Query: 302 PSSARGYQGYPG----GDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRS 357 G G PG + GPQ GP G Sbjct: 888 -----GMPGAPGLWMGSSWQPGPQGPPGIPGPP-------GPPGVPGLQGV--------- 926 Query: 358 HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGP----PSGPQQ 413 PG++G GQP S P++Q + G Q+ P G + Sbjct: 927 ------PGNNGLPGQPGLTAELGSLPIEQH---LLKSICGDCVQGQRAHPGYLVEKGEKG 977 Query: 414 GHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQ--IPPYGQQGPSGY-GQQGQT-P 469 G PG P Q + + RA+ A G S + G GP G GQ+G+ P Sbjct: 978 DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037 Query: 470 YYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQ--------------PQSQPPQLQSSQ 515 + SP P P +P P Q + P QP ++ Sbjct: 1038 PGMRGSPGPPGPIGPPGFPGAVGSP-GLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATG 1096 Query: 516 PP----------------YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559 PP +P P + P P ++ PQ S + Sbjct: 1097 PPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGN---SGEKGDQG 1153 Query: 560 YQQQQ--PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPS 617 +Q Q P P P + P P Q+++ + R P S G P+ Sbjct: 1154 FQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGI-RGPSGLPGSPGPPGPPGIQGPA 1212 Query: 618 MTSSKGGQEDM-NLSLQSRPSSLPDLSGSIDDLPMGTEGALS-PGV----------STSG 665 G++ L P+ P L G P G +G PG+ G Sbjct: 1213 GLDGLDGKDGKPGLRGDPGPAGPPGLMG-----PPGFKGKTGHPGLPGPKGDCGKPGPPG 1267 Query: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSR---------SGPLSP 716 + G + P P P PG GP P P G P S +G Sbjct: 1268 STGRPGAEGEPGA--MGPQGRPGPPGHVGP-PGPPGQPGPAGISAVGLKGDRGATGERGL 1324 Query: 717 AAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQP 776 A +PG PP P + + + +G+ P PG+A Q Sbjct: 1325 AGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYG-----PPGPKGDPGAAGQKGQ- 1378 Query: 777 SGGQIHTGM--GSYQQNSMGSYGPQG--------GQYGPQG--GYPRQP-------NYNA 817 +G + GM G + SMG GP G G GP G G P P NY+ Sbjct: 1379 AGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDE 1438 Query: 818 LPN------ANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPN 871 + MA + M +M PG P PPG+ RP P Sbjct: 1439 IKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPG----PPGK---DGAPGRPGAPG 1491 Query: 872 MANMPPQVG----SGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMG-T 926 +P Q+G G+ G K ++ + + +A + PPG G MG T Sbjct: 1492 SPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGAT 1551 Query: 927 GPPYGQGINSMAGMINPQGPPYSMG 951 GP QGI + G P G P G Sbjct: 1552 GPMGQQGIPGIPGPPGPMGQPGKAG 1576 Score = 77.8 bits (190), Expect = 1e-13 Identities = 238/1020 (23%), Positives = 308/1020 (30%), Gaps = 163/1020 (15%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGG---EAAAAAAAERGEMKAAAGQESEGPAV 63 P G P P P+ Q + E G ++ A+ A + P Sbjct: 524 PGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGF 583 Query: 64 GPPQPLGKELQDGAESNGG--GGGGGAGSGGGPG--AEPDLKNSNGN-AGPRPALNNNLT 118 G P G+ G + G G G AGS G PG +K + G P PAL+N Sbjct: 584 GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643 Query: 119 EPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQS 178 G V P S P P GFG P G+Q Sbjct: 644 --------GDVRVVALPGPSGEKGEPGPP-GFGLP---------------------GKQG 673 Query: 179 PGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG-- 236 G GL+ G N D G P + P S P + P G Sbjct: 674 -------KAGERGLKGQKGDAGNPGDPGTPG---TTGRPGLSGEP------GVQGPAGPK 717 Query: 237 GTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTL 295 G G G A + + A +Q G G G P G G P P L Sbjct: 718 GEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQ--GPEGVGRPGKPGQPGLPGVQGPPGL 775 Query: 296 NQLLTSPS----SARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG 351 + P +G QG PG G Q +GP + + A Sbjct: 776 KGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPV 835 Query: 352 GAQQRSHHAPMSPGSSGGGGQP-LARTPQPSSPMDQMGKMRPQ--PYGGTNPYSQQQGPP 408 G S P PG G GQ L TP P + G+ P G +S G P Sbjct: 836 GPPGASVSGP--PGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAP 893 Query: 409 S---------GPQQGHGYPGQPYGSQTP--QRYP----MTMQGRAQSAMGGLSYTQQIPP 453 GPQ G PG P P Q P + Q + +G L Q + Sbjct: 894 GLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLK 953 Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPS-------QTPHAQPSYQQQPQS 506 G GQ+ Y ++ Q P + P A+ + + Sbjct: 954 -SICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEG 1012 Query: 507 QPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ 566 P + S P P P Q+ P + + PP SP Sbjct: 1013 DPGCVGSPGLP---GPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQG 1069 Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626 + + L+ P P Q Y PP + G S+ G E Sbjct: 1070 ERGLTGLTGDKGEPGPPGQPG----YPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSE 1125 Query: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPF-SPHT 685 LP G P G G P G S +G+Q Q F P Sbjct: 1126 -----------GLPGPPG-----PAGPRGERGP----QGNSGEKGDQGFQGQPGFPGPPG 1165 Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745 P PG G SP P G A + G P+ +PG+ PP PP Q + + + Sbjct: 1166 PPGFPGKVG-SPGPPGPQAE--KGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDG 1222 Query: 746 IAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQY 803 RG P P P G + TG G GP+G G+ Sbjct: 1223 KPGLRG------------DPGPAGPPGLMGPPGFKGKTG-------HPGLPGPKGDCGKP 1263 Query: 804 GPQGGYPRQPNYNALPNANYPSA--GMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHA 861 GP G R P P A P G G + P G GQ G GI G + Sbjct: 1264 GPPGSTGR-PGAEGEPGAMGPQGRPGPPGHVGPPGPPGQ-PGPAGISAVGL----KGDRG 1317 Query: 862 SMGNRPYGPNMANMPPQVG-SGMCPPPG-----GMNRKTQETAVAMHVAANSIQNRPPGY 915 + G R +A +P Q G G PPG G K + P Sbjct: 1318 ATGER----GLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAA 1373 Query: 916 PNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMG-LGDV 973 Q G G G P G G + G + P GP G A +G P + G +GD+ Sbjct: 1374 GQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDM 1433 Score = 73.6 bits (179), Expect = 2e-12 Identities = 129/547 (23%), Positives = 178/547 (32%), Gaps = 97/547 (17%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA---- 62 P S G P PP P+ R E G + + ++G GP Sbjct: 1119 PGPPGSEGLPGPPGPAG-------PRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPG 1171 Query: 63 -VGPPQPLGKELQDGAESNGGGGG--GGAGSGGGPGAE-----PDLKNSNGNAG----PR 110 VG P P G + + G+E G G G G G PG + L +G G P Sbjct: 1172 KVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPG 1231 Query: 111 PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF----GQPYGRSPSAVAAAAA 166 PA L PPG G G+ P PP + G G+P P Sbjct: 1232 PAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPG 1291 Query: 167 AVFHQQHGGQQSP-GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP 225 V GQ P G++A+ G G G G P H PP Sbjct: 1292 HVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPG----------PPG 1341 Query: 226 APAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGG 285 P ++ + G PG G P +A + + R G GG G S + G Sbjct: 1342 EPGTDGAAGKEGPPGK--QGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGP 1399 Query: 286 TPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345 P P+ RG+ G PG SG P G DM + + Sbjct: 1400 VGPP-----------GPAGERGHPGAPGP--SGSPGLPGVPGSMGDMVN--YDEIKRFIR 1444 Query: 346 AAAASGGAQQRSHHA-----PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400 ++ +++ PM ++ G P + P P Sbjct: 1445 QEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRP----------------- 1487 Query: 401 YSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTM-----QGRAQSAMGGLSYTQQIP-PY 454 G P P G PGQ G + Q P +G G++ +P P Sbjct: 1488 -----GAPGSP----GLPGQ-IGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPP 1537 Query: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS--YQQQP-QSQPPQL 511 G QGP GYG+ G T QQ P PP P + H PS + P + Q P + Sbjct: 1538 GPQGPPGYGKMGATGPMGQQG-IPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPM 1596 Query: 512 QSSQPPY 518 ++ + P+ Sbjct: 1597 KTMKGPF 1603 Score = 65.9 bits (159), Expect = 4e-10 Identities = 162/695 (23%), Positives = 219/695 (31%), Gaps = 115/695 (16%) Query: 94 PGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQP 153 P AE + + N P + L PPG G +G PP + PP G P Sbjct: 1000 PRAE-EARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEG---PPGMRGSPGPPGPIG---P 1052 Query: 154 YGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYN 213 G P AV SPGL LQ G GL G D G P Sbjct: 1053 PG-FPGAVG---------------SPGLPGLQ--GERGLTGLTG------DKGEPGPPGQ 1088 Query: 214 SYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGA 273 YP + PP P + RG T G+A G PP S + + G Sbjct: 1089 PGYPGATG-PPGLPG--IKGERGYT---GSAGEKGEPGPPGSEGLPGPPGPAGPRGERGP 1142 Query: 274 MGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQ--DGGAG-KGPA 330 G G G QP P G+ G G GPQ G G +GP+ Sbjct: 1143 QGNSGEKGDQGFQGQPG--------FPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPS 1194 Query: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP--------LARTPQPSS 382 + A G + P G G G P +T P Sbjct: 1195 GLPGSPGPPGPPGIQGPAGLDGLDGKDGK-PGLRGDPGPAGPPGLMGPPGFKGKTGHPGL 1253 Query: 383 PMDQMGKMRPQPYGGTN-PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441 P + +P P G T P ++ + GPQ G PG G P P A Sbjct: 1254 PGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGH-VGPPGPPGQPGPAGISAVGL 1312 Query: 442 MGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPS-QTPHAQPSY 500 G T G++G +G Q P + P + PP Q + P Sbjct: 1313 KGDRGAT------GERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGP 1366 Query: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPY-PSQQSTTQQHPQSQPPYSQPQAQSP 559 + P + + Q+ + + P P S P P + + HP + P P Sbjct: 1367 KGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPG- 1425 Query: 560 YQQQQPQQPAPSTLSQQAAYPQPQ--------SQQSQQTAYSQQRFPPPQELSQDSFGSQ 611 P ++ Y + + ++ AY R P E++ Sbjct: 1426 ---------VPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMA------- 1469 Query: 612 ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS-PGVSTSGISSSQ 670 +AP G +D P S P L G I G EG PGV G+ ++ Sbjct: 1470 --AAPGRPGPPG--KDGAPGRPGAPGS-PGLPGQI-----GREGRQGLPGVR--GLPGTK 1517 Query: 671 GEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730 GE+ + + G+ GP P P G P +GP+ +PG PP P Sbjct: 1518 GEKGDIGIGIAGEN------GLPGP-PGPQGPPGYGKMGATGPMGQQGIPGIPGPP-GPM 1569 Query: 731 GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765 GQ H N S Q+ P M P Sbjct: 1570 GQPGKAGH--CNPSDCFGAMPMEQQYPPMKTMKGP 1602 Score = 32.3 bits (72), Expect = 5.5 Identities = 57/215 (26%), Positives = 67/215 (31%), Gaps = 31/215 (14%) Query: 1110 GEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEG--GDLKPPTPAS 1167 G PP + K P P G GP P ST AEG G + P Sbjct: 1231 GPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGP--PGSTGRPGAEGEPGAMGPQGRPG 1288 Query: 1168 TPHSQIPP----LPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGR 1223 P PP PG + ++VG++ D + PG G Sbjct: 1289 PPGHVGPPGPPGQPGPAGISAVGLK------GDRGATGERGLAGLPGQPGPPGHPGPPG- 1341 Query: 1224 MSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGG 1283 EP D PG F GP G GDP A G R P GG Sbjct: 1342 ---EPGTDGAAGKEGPPGKQGF----YGPPGPKGDP---GAAGQKGQAGEKGRAGMP-GG 1390 Query: 1284 PYDRVRTEPGIGPEGNMS----TGAPQPNLMPSNP 1314 P P +GP G GAP P+ P P Sbjct: 1391 PGKSGSMGP-VGPPGPAGERGHPGAPGPSGSPGLP 1424 >gi|55956910 meningioma 1 [Homo sapiens] Length = 1320 Score = 103 bits (256), Expect = 3e-21 Identities = 288/1239 (23%), Positives = 401/1239 (32%), Gaps = 273/1239 (22%) Query: 97 EPDLKNSNGNAGPRP------ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAAL-PPPAYG 149 EP + + N G R ++N + P GG P A +AL PP G Sbjct: 8 EPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPG-----PVDPAMSALGEPPILG 62 Query: 150 FG-QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSGGG-GGLEPYAGPQQNSHDHG 206 +PYG FH + H + GL A G GG +P+ G + H H Sbjct: 63 MNMEPYG-------------FHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPH- 108 Query: 207 FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS---ASASSSS 263 Q++ ++ P P + G GAA GS+PP + + S Sbjct: 109 ----QHHPHFGGNFGGPDPGASCLHGGRLLGY--GGAAGGLGSQPPFAEGYEHMAESQGP 162 Query: 264 SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG----- 318 SF QR G + S A P L SP+ A + G P S Sbjct: 163 ESFGPQRPGNLPDFHSSGASSHAVPAPCLP----LDQSPNRAASFHGLPSSSGSDSHSLE 218 Query: 319 -------GPQD-------GGAGKGPADM--ASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362 G D G A G DM S G AA GGA + P Sbjct: 219 PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278 Query: 363 SPGSSGGG---GQPLARTPQPSSPMDQ-------------------------MGKMRP-- 392 + G G QP + PQ Q +G P Sbjct: 279 AAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLM 338 Query: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG-----SQTPQRYPMTMQGRAQSAMGGLSY 447 QP P QQQ P PQQ P P G + P P QG A + GGL Sbjct: 339 QPPQQAPPPPQQQPPQQPPQQ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ- 394 Query: 448 TQQIPPYGQQGPSGYGQQGQTPY----YNQQSPHPQQQQPPYSQQ--PPSQTPHAQ---- 497 GP Q Q Y +S HP + P +S Q PP Q P+ + Sbjct: 395 --------DGGPMLPSQHAQFEYPIHRLENRSMHPYSE-PVFSMQHPPPQQAPNQRLQHF 445 Query: 498 --PSYQQ----------------------------------QPQSQPPQLQSSQPPYSQQ 521 P Y P + P PP Sbjct: 446 DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDS 505 Query: 522 -PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP 580 PS PP Q + S Q QQ Q Q Q Q Q QQQQ +Q A + Q A+ Sbjct: 506 FPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS-- 563 Query: 581 QPQSQQSQQTAYSQQRFP------------PPQELSQDSFGSQASSAPSMTSSKGGQEDM 628 + Q Q+ +Q +Q P P L+Q +F + S + Q+ Sbjct: 564 RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAP 623 Query: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688 +L+ +S S P D LP G SG+ + G PH Sbjct: 624 HLAQESAWFSGPHPPPG-DLLPRRMGG--------SGLPADCG---------------PH 659 Query: 689 LPGIRGPSPSPVGSPASVAQSRSGPL-SPAAVPGNQMPPRPPS------GQSDSIMHPSM 741 P + P P P GS GPL P +PG P PS G + Sbjct: 660 DPSL-APPPPPGGSGVLF----RGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQS 714 Query: 742 NQSSIAQDRGYMQRNPQMPQYSSP----QPGSALSPRQPSGGQI--HTGMGSYQQNSMGS 795 + + +R P P +++ QPG P +G Q H+G G S G Sbjct: 715 PGAGVGLPSAASERRPPPPDFATSALGGQPG---FPFGAAGRQSTPHSGPGVNSPPSAGG 771 Query: 796 YGPQGGQYGPQGGYPRQPNYNALPNANYPSAG--MAGGINPMGAGGQMHGQPGIPPYGTL 853 G G G G YP QP++ + G G N + + GQ + T Sbjct: 772 GGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTA 831 Query: 854 PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913 + AS+G PN+ V PP G + +Q VA N P Sbjct: 832 CQNMI--ASLG----APNL-----NVTFNKKNPPEGKRKLSQNETDGAAVAGN------P 874 Query: 914 G---YPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 G +P G G G P G +S + P PP GT + + + ++ G Sbjct: 875 GSDYFPGGTAPGAPGPGGPSGTS-SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG- 932 Query: 971 GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAF 1030 P + + G K +S S T +K + + GG P V Sbjct: 933 -----KPVSGGGGRGRGRRKRDS---GHVSPGTFFDKYSAAPDSGGAP----GVSPGQQQ 980 Query: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090 A+G ++ P + S G + ++ +L +L+ G S ++S Sbjct: 981 ASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQP--DLIGSLDGGAKSDSSS 1038 Query: 1091 ----SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSK--KSQPKIQPPSPAGSGSMQGP 1144 + YA E ++ D P + A+ S PK+ PP G+G GP Sbjct: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKL-PPRGVGAGE-HGP 1096 Query: 1145 QTP----------QSTSSSMAEGGDLKPPTPASTPHSQI 1173 + P STS+ + GG P P + Q+ Sbjct: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135 Score = 81.6 bits (200), Expect = 8e-15 Identities = 267/1221 (21%), Positives = 392/1221 (32%), Gaps = 236/1221 (19%) Query: 191 GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK 250 GL+ + PQ NS + G +N + + + APA+ P G P A +A G Sbjct: 3 GLDQFE-PQVNSRNAGQGERNFNETGLSMNTHFK-APAFHTGGPPG--PVDPAMSALGEP 58 Query: 251 PPPSSSASASSSSSSFAQQRFGAMGGGGPSAA------GGGTPQPTATPTLNQLLTSPSS 304 P + F + + GG A GG P P S Sbjct: 59 P----ILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG----------HPGS 104 Query: 305 ARGYQGYP--GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362 +Q +P GG++ GGP G + + A + A G P Sbjct: 105 HHPHQHHPHFGGNF-GGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPE 163 Query: 363 SPGSSGGGGQPLART--------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414 S G G P + P P P+DQ P+ Sbjct: 164 SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQS--------------------PNRAASF 203 Query: 415 HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-------GQQGQ 467 HG P GS + P + Q A+ L Y Y + PSG+ +GQ Sbjct: 204 HGLPSSS-GSDSHSLEPRRVTN--QGAVDSLEYN-----YPGEAPSGHFDMFSPSDSEGQ 255 Query: 468 TPYYNQQSPHPQQQQPPYSQQPPS------QTPHAQPSYQQQPQSQPPQLQSSQPPYSQQ 521 P+Y P P S P + HAQP QQ Q Q PQ Q Q + Sbjct: 256 LPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFE 315 Query: 522 PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ 581 + P + S +HP QPP QA P QQQ PQQP PQ Sbjct: 316 RFSGARKM---PVGLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQP-----------PQ 358 Query: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641 Q Q PP Q + PS GG +D L S+ + Sbjct: 359 QQPPPPPGLLVRQNSCPPALPRPQQG----EAGTPS-----GGLQDGGPMLPSQHAQFEY 409 Query: 642 LSGSIDDLPMG--TEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHL--PGIRGPSP 697 +++ M +E S + +Q Q A + P PG G Sbjct: 410 PIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDR 469 Query: 698 SPVGSPASVAQSRSGPLSPAA---VPGNQMPPRPPSGQSDS-IMHPSMNQSSIAQDRGYM 753 + + + LSP+A +PG PP P S S + HP+ + S+ Q + Sbjct: 470 CASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQ 529 Query: 754 QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQP 813 Q+ Q Q Q ++ + + M S Q RQP Sbjct: 530 QQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR----------------LRQP 573 Query: 814 NYNALPNANYPSAGMAGGINPMGAGGQMHGQP--GIP-PYGTLPPGRMSHASMGN-RPYG 869 N L G +G GG +HG P G+ P G +G Sbjct: 574 NLAQL-----------GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQA 622 Query: 870 PNMANMPPQVGSGMCPPPGGM-NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGP 928 P++A SG PPPG + R+ + + + PP P Sbjct: 623 PHLAQESAWF-SGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP-------------P 668 Query: 929 PYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGT 988 P G G+ + P P G A S G+ + GLG ++ A G Sbjct: 669 PGGSGVLFRGPLQEPMRMP-GEGHVPALPSPGLQFGGSLGGLGQLQSPGA------GVGL 721 Query: 989 PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGR-- 1046 P S+ + T+ LGG+P + T G+ + P+ G Sbjct: 722 PSAASERRPPPPDFATSA-------LGGQPGFPFGAAGRQS-TPHSGPGVNSPPSAGGGG 773 Query: 1047 --------------KPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSL 1092 +P S ++G L+ + NK + NL + +A S+ Sbjct: 774 GSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSK--DNLFGQSCLAALSTA 831 Query: 1093 KKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQ---------- 1142 + I L A + + PP+ K SQ + + AG+ Sbjct: 832 CQNMIASLGAPNLNVTFNKKNPPE----GKRKLSQNETDGAAVAGNPGSDYFPGGTAPGA 887 Query: 1143 -GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQK 1201 GP P TSSS ++ P S P S S + G + G +K Sbjct: 888 PGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRK 947 Query: 1202 RNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYS 1261 R+S +PG + S P+ G P +S GQ Sbjct: 948 RDSGHVSPG--------TFFDKYSAAPDS----------GGAPGVSPGQ----------Q 979 Query: 1262 RAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSP 1321 +A+G +G + G + P P+++ T P G + G QP+L+ S D G S Sbjct: 980 QASGAAVGGSSAGETRGAP--TPHEKALTSPSWGKGAELLLG-DQPDLIGS-LDGGAKSD 1035 Query: 1322 SRYPPQQQQQQQQRHDSYGNQ 1342 S P + + SY N+ Sbjct: 1036 SSSPNVGEFASDEVSTSYANE 1056 Score = 60.1 bits (144), Expect = 2e-08 Identities = 130/561 (23%), Positives = 180/561 (32%), Gaps = 112/561 (19%) Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSG---GGPGAEPDLKNSNGNAGPRPALNNNL 117 P++ PP P G GSG GP EP G+ P+ Sbjct: 661 PSLAPPPPPG------------------GSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702 Query: 118 TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG-QPYGRSPSAVAAAAAAVFHQQHGGQ 176 GG G S G G SAA+ PP F G P AA +Q Sbjct: 703 GGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG----RQSTPH 758 Query: 177 QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP---APAYALSS 233 PG+ + S GGGG G AYPP P+ S+ Sbjct: 759 SGPGVNSPPSAGGGGGSSGGG-------------------GGGGAYPPQPDFQPSQRTSA 799 Query: 234 PRGGTPGSGAAAAAGSKPPPSS-----SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288 + G A + GS PSS S ++ S+ Q ++G + Sbjct: 800 SKLG------ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP 853 Query: 289 PTATPTLNQLLTSPSSARGYQG---YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345 P L+Q T ++ G G +PGG G P G GP+ +S A+ Sbjct: 854 PEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG----GPSGTSSSGSKASGPPNP 909 Query: 346 AAAASGGAQQRSHHAPMSPGS-----SGGGGQPLARTPQPS---SPMDQMGKMRPQP-YG 396 A G + ++ + G+ SGGGG+ R + S SP K P G Sbjct: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969 Query: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAM-------------- 442 G S Q SG G G+ G+ TP +T + A Sbjct: 970 GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029 Query: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQ-----QSPHPQ----QQQPPYSQQPPSQT 493 GG P G+ + T Y N+ S +PQ + P P Sbjct: 1030 GGAKSDSSSPNVGEFA----SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085 Query: 494 PHAQPSYQQQPQSQPPQL-------QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ--- 543 P + + P++ PP L +S P P H +P + T+ Sbjct: 1086 PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 Query: 544 HPQSQPPYSQPQAQSPYQQQQ 564 P P QAQ Q+QQ Sbjct: 1146 PPDEIHPLEILQAQIQLQRQQ 1166 Score = 57.4 bits (137), Expect = 2e-07 Identities = 107/440 (24%), Positives = 143/440 (32%), Gaps = 72/440 (16%) Query: 24 LKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES---EGPAVGPPQPLGKELQDGAESN 80 L A ++R A +A + G AAG++S GP V P + Sbjct: 721 LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP------------S 768 Query: 81 GGGGGGGAGSGGGPGA---EPDLKNS-NGNAGPRPALNNNLTEPPGGG----GGGSSDGV 132 GGGGG +G GGG GA +PD + S +A AL+ P G + Sbjct: 769 AGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAAL 828 Query: 133 GAPPHSAAAALPPPAYGF-----GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSG 187 + A+L P P G+ + A G PG A + Sbjct: 829 STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP 888 Query: 188 GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAA 245 G GG P S G PN P + +P Y L S G G P SG Sbjct: 889 GPGG--PSGTSSSGSKASGPPNP------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940 Query: 246 AAGSKPPPSS------------SASASSSS----SSFAQQRFGAMGGGGPSAAGGGTPQP 289 + S SA+ S S QQ GA GG + G P P Sbjct: 941 RGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTP 1000 Query: 290 TATPTLNQLLTSPSSARGYQGYPG------GDYSGGPQDGGAGKGPADMASQCWGAAAAA 343 + LTSPS +G + G G GG + + + AS + A Sbjct: 1001 H-----EKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN 1055 Query: 344 AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403 ++S Q A SP +G + P + G P P G S Sbjct: 1056 EDEVSSSSDNPQALVKASRSPLVTGS-----PKLPPRGVGAGEHGPKAPPPALGLGIMSN 1110 Query: 404 QQGPPS--GPQQGHGYPGQP 421 P G G G+PG P Sbjct: 1111 STSTPDSYGGGGGPGHPGTP 1130 Score = 52.4 bits (124), Expect = 5e-06 Identities = 85/329 (25%), Positives = 116/329 (35%), Gaps = 82/329 (24%) Query: 20 PPSELKKAEQQQREEA------------GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67 PP +K Q + + A GG A A +++G ++ GP P Q Sbjct: 853 PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQ 912 Query: 68 PLGKELQDG--AESNGGGGG----GGAGSGGG----------PGAEPDLKNSNGNAGPRP 111 G L ES G G GG G G G PG D ++ ++G P Sbjct: 913 GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAP 972 Query: 112 ALNNNLTEPPGGGGGGSSDGV--GAP-PHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168 ++ + G GGSS G GAP PH A P G G P + Sbjct: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLI------- 1025 Query: 169 FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHG-FPNHQYNSYYPNR-----SAY 222 G L+ A +S + G F + + ++ Y N S+ Sbjct: 1026 ---------------------GSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064 Query: 223 PPPAPAYALSSPR-GGTP-----GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276 P A A SP G+P G GA PPP+ S+S+S +G GG Sbjct: 1065 NPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS-TPDSYG--GG 1121 Query: 277 GGPSAAGGGTPQPTATPTLNQLLTSPSSA 305 GGP G TP L Q+ T SS+ Sbjct: 1122 GGPGHPG--------TPGLEQVRTPTSSS 1142 Score = 47.0 bits (110), Expect = 2e-04 Identities = 95/418 (22%), Positives = 135/418 (32%), Gaps = 88/418 (21%) Query: 1267 GLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPP 1326 G G A G P+ Y+ + G PE S G +P +P SG S + P Sbjct: 135 GYGGAAGGLGSQPPFAEGYEHMAESQG--PE---SFGPQRPGNLPDFHSSGASSHAVPAP 189 Query: 1327 -QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGP----PA 1381 Q R S+ S+ G+ S S P + T Y P + G Sbjct: 190 CLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSP 249 Query: 1382 KRHEGEM-----------------YSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424 EG++ ++P + G + P Q QP QQQ Q Q Sbjct: 250 SDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQ 309 Query: 1425 QDVYNQ---------------YGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPG 1469 V+ + G+ +P P PQ Q P Q + + PPG Sbjct: 310 HGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPP---PQQQPPQQPPQQQPPPPPG 366 Query: 1470 TNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRT 1529 +QN P + P Q A GT G D P P+ H + Sbjct: 367 LLVRQNSCPPALPRPQQGEA-----GTPSGGLQD------------GGPMLPSQHA--QF 407 Query: 1530 DEMLH-TDQRANHEGSWPSHGTRQPP--YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVS 1586 + +H + R+ H S P + PP P+ + PP N P Sbjct: 408 EYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRF-----DFP 462 Query: 1587 SPAPLPR-----------PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1633 A + R ++N SPS P L + PPVP S + P+Q P Sbjct: 463 GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG-----EFTPPVPDSFPSGPPLQHP 515 Score = 44.3 bits (103), Expect = 0.001 Identities = 75/300 (25%), Positives = 97/300 (32%), Gaps = 61/300 (20%) Query: 1128 PKIQPPSPAGSGSMQGP--QTPQSTSSSMAEGGDLKPPTPA------STPHSQIPPLPGM 1179 P +QPP A Q P Q PQ PP P S P + P G Sbjct: 336 PLMQPPQQAPPPPQQQPPQQPPQQQP----------PPPPGLLVRQNSCPPALPRPQQGE 385 Query: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKA 1239 + + S G+QD M P+ Q + R S P +P SM+ Sbjct: 386 AGTPSGGLQDG------------GPMLPSQHAQFEYPIHRLENR-SMHPYSEPVFSMQHP 432 Query: 1240 PGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEG- 1298 P Q PN + P NVA PR +P DR + G G Sbjct: 433 PPQ-------QAPNQRL----QHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGA 481 Query: 1299 ---NMSTGA----------PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345 ++S A P P+ PS P +P QQQQQQQQ+ Q Sbjct: 482 LDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541 Query: 1346 QGTPSGSPFPSQQTTMYQQ-----QQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQP 1400 Q M +Q QQQ ++P G P +G + G QP Sbjct: 542 QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQP 601 Score = 32.3 bits (72), Expect = 5.5 Identities = 75/345 (21%), Positives = 107/345 (31%), Gaps = 78/345 (22%) Query: 1116 DIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPP 1175 D+F+ +DS+ P G+ G ++ M + P P Q P Sbjct: 245 DMFSPSDSEGQLPHYAAGRQVPGGAFPGASA-MPRAAGMVGLSKMHAQPPQQQPQQQQQP 303 Query: 1176 LPGM------------SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGR 1223 +R VG++ + Q P P QP Sbjct: 304 QQQQQQHGVFFERFSGARKMPVGLEPSVGS-RHPLMQPPQQAPPPPQQQPPQQPPQQ--- 359 Query: 1224 MSYEPNKDPYGSMRK--APGSDPFMSSGQG--PNGGMGDPYSRAAGPGLGNVAMGPRQHY 1279 +P P +R+ P + P G+ P+GG+ D GP L P QH Sbjct: 360 ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD-----GGPML------PSQHA 405 Query: 1280 PYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP-SNPDSGMYSPSRYPPQQQQQQQQRH-- 1336 + P R+ ++ P S P M P PPQQ Q+ +H Sbjct: 406 QFEYPIHRLENR----------------SMHPYSEPVFSMQHP---PPQQAPNQRLQHFD 446 Query: 1337 -DSYGN-----QFSTQGTPSGSPFPSQQTTMYQQQQQNYKRP-----MDGTYGPPAKRHE 1385 Y N +F G+ S +M+ N+ P + G + PP Sbjct: 447 APPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP----- 501 Query: 1386 GEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQ 1430 VP S G P Q P Q QQQ Q QQ Q Sbjct: 502 -----VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541 Score = 32.0 bits (71), Expect = 7.2 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 3/59 (5%) Query: 55 GQESEGPAVGPPQPLGKELQDGAES--NGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRP 111 G GP PP LG + + S + GGGGG G G PG E ++ + P P Sbjct: 1090 GAGEHGPKA-PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 103 bits (256), Expect = 3e-21 Identities = 253/1049 (24%), Positives = 322/1049 (30%), Gaps = 161/1049 (15%) Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75 PP PP S K Q ++ G + + GQ GPP LG Q Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514 Query: 76 GAESNGGGGG--GGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDG 131 G + G G G G G PGA P K G+ P + + E G G Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574 Query: 132 VGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGG 191 G P LP P G+P G F + G +PGL L G Sbjct: 575 PGTPGQDGLPGLPGPK---GEPGG-----------ITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 192 LEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPA--PAYALSSP-RGGTPGS-GAAAAA 247 P GP + G N P + P P P ++ P + G PG+ G Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGN---PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 248 GSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG 307 G P ++ G G G P G P P P + P A G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPPGPKGFPGI----PGPPGAPG 728 Query: 308 YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP--- 364 G G + GP KG A A G R P P Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788 Query: 365 ----------GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ----------- 403 G G GQP P + G P P G P Q Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP--PGPPGIPGPIGQPGLHGIPGEKG 846 Query: 404 QQGPPS----GPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ-QIPPYGQQG 458 GPP GP G PG P G+ P P + ++ G T+ ++ G G Sbjct: 847 DPGPPGLDVPGPPGERGSPGIP-GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG 905 Query: 459 PSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPP 517 P G G G++ + Q QP + +P P P L S+ Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 518 YSQQPSQP--PHQQSPAPY------PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569 + P P P P Y P Q + Q PP + P Q P Sbjct: 966 KGE-PGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024 Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629 +P PQ + PP GS P + KG + D Sbjct: 1025 LKGTIGDMGFPGPQGVEG----------PPGPSGVPGQPGS-----PGLPGQKGDKGDPG 1069 Query: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQSPFSPHTS-- 686 +S LP L G P G G PG GI S G+ P P +P Sbjct: 1070 IS----SIGLPGLPG-----PKGEPGL--PGYPGNPGIKGSVGDPGLPGL-PGTPGAKGQ 1117 Query: 687 PHLPGIRG----PSPSPVGSPASVA--QSRSGPLSPAAVPGNQMPP--RPPSGQSDSIMH 738 P LPG G P P + P GP+ PG PP + GQ D I Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ-DGIPG 1176 Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSPQ-----PGSALSPRQPSGGQIHTGMGSYQQNSM 793 P+ + Q P +P S + PG +P P G + G + Sbjct: 1177 PAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKGEPGFHGFP-GVQ 1234 Query: 794 GSYGPQG----------GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843 G GP G G GPQG P +P + LP P G+ G G G G Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGP-PGRPGFQGLPGPEGPP-GLPGNGGIKGEKGNP-G 1291 Query: 844 QPGIPPYGTLP-----------PGRMSHASMGNRPYGPNMANMPPQVG-SGMCPPPGGMN 891 QPG+P L PGR M P P + P G SG+ PG Sbjct: 1292 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV---PGSAG 1348 Query: 892 RKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM---GTGPPYGQGINSMAGMINPQGPPY 948 + + + PPG P + ++ GPP G + G+ PQGP Sbjct: 1349 PEGEPGLIG--------PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1400 Query: 949 SMGGTMANNSAGMAASPEMMGLGDVKLTP 977 G T G P G G K P Sbjct: 1401 LPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1429 Score = 91.7 bits (226), Expect = 8e-18 Identities = 208/882 (23%), Positives = 264/882 (29%), Gaps = 165/882 (18%) Query: 60 GPAVGPPQPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAG------ 108 GP P Q + + + G N G G G G G PG P + S G G Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL-PGIPGSKGEPGIPGIGL 708 Query: 109 ---PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAA 165 P P + PPG G G+ PP P GF P P + Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768 Query: 166 AAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP 225 A+ + G P G GL+ GP+ + +G P P PP Sbjct: 769 GALGPKGDRGFPGPP----GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP 824 Query: 226 APA-----------YALSSPRG----------GTPGS----GAAAAAGSKPPPSSSASAS 260 P + + +G G PG G A G PP S Sbjct: 825 GPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884 Query: 261 SSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLN--------QLLTSPSSARGYQG 310 + +S G MG GP G G P + P L L P+ +G +G Sbjct: 885 KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944 Query: 311 YPGGDYSGGPQD----GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS 366 PG GP D G G+ G + Q P PG Sbjct: 945 EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004 Query: 367 SGGGGQP-------LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP----QQGH 415 G G P L P + MG PQ G S G P P Q+G Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Query: 416 ------------------------GYPGQP-----YGSQTPQRYPMTMQGRAQSAMGGLS 446 GYPG P G P T + Q + G Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124 Query: 447 YTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505 T P P G GP G P HP Q PP + P Q P+ Q+ Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184 Query: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQ-PQAQSPYQQQQ 564 QP P Q P P P+ +P + P Q P Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPG-IPGNPGLPG--PKGEPGFHGFPGVQGP--PGP 1239 Query: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGG 624 P P P+ L P PQ + Q P P+ P + + G Sbjct: 1240 PGSPGPA-LEGPKGNPGPQGPPGRP---GFQGLPGPE------------GPPGLPGNGGI 1283 Query: 625 QEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPH 684 + + Q LP L G D P G +G +PG G++ +G+ P Sbjct: 1284 KGEKGNPGQPGLPGLPGLKG--DQGPPGLQG--NPG--RPGLNGMKGDPGLPGV------ 1331 Query: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744 P PG++GPS P G P PG PP PP + PS Sbjct: 1332 --PGFPGMKGPSGVP------------GSAGPEGEPGLIGPPGPP-----GLPGPSGQSI 1372 Query: 745 SIAQDRGYMQRNPQMPQYSSPQPG--SALSPRQPSGGQIHTG-MGSYQQNSMGSYGPQGG 801 I D G P QPG P+ P G TG G +N + + GG Sbjct: 1373 IIKGDAG--------PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1424 Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843 + G G P QP L P G+ G P G HG Sbjct: 1425 RKG-DPGLPGQPGTRGLDGPPGPD-GLQGPPGPPGTSSVAHG 1464 Score = 90.9 bits (224), Expect = 1e-17 Identities = 244/1051 (23%), Positives = 321/1051 (30%), Gaps = 151/1051 (14%) Query: 13 LGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKE 72 L P P + E+ Q+ + G R G++ G P G+ Sbjct: 314 LPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373 Query: 73 LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV 132 G + G G + GP P G G ++ PPG G + G+ Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL 433 Query: 133 GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192 PP A + PP+ +P P + + G + G G G Sbjct: 434 PGPPGPAGPHI-PPSDEICEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG-- 488 Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGS-GAAAAAGS 249 +GP G P + +P + A A + P+G G PG+ GA GS Sbjct: 489 --ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA---TGPKGLPGIPGAPGAPGFPGS 543 Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSAR- 306 K P + G +G G G GTP P L P Sbjct: 544 KGEPGDILTFPGMKGD-----KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Query: 307 -------GYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH 359 G G PG + GP G G GP + A G + Sbjct: 599 KGERGPPGNPGLPGLPGNIGPM-GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 360 APMSPGSSGGGGQP-------LARTP----QPSSPMDQMGKMRPQPYGGTNPYSQQQGPP 408 PG G G P L P QP P K P G P GPP Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPP 712 Query: 409 SGPQQGHGYPGQPYGSQTPQRYPMT----------MQGRAQSAMGGLSYTQQIP------ 452 GP+ G PG P TP R + +G A+ G +P Sbjct: 713 -GPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771 Query: 453 -PYGQQG-PSGYGQQGQTPYYNQQSPH----PQQQQPPYS---------QQPPSQTPHAQ 497 P G +G P G G+T P P Q P Q PP Sbjct: 772 GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP----APYPSQQSTTQQHPQSQPPYSQ 553 P Q P + PP P P + SP AP P + P Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 554 PQAQSPY-QQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612 P + P P P + ++ P + Q Q P P Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ---GQPGLPGP------------ 936 Query: 613 SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL-SPGV-STSGISSSQ 670 T KG + + LP G +D +G++G PG+ G+S + Sbjct: 937 ------TGEKGSKGE---------PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 671 GEQSNPAQSPFSPHTS--PHLPGIRGPSPSP--VGSPASVA----------------QSR 710 G Q P P P S P LPG GP +P G P + Q Sbjct: 982 GYQGLPG-DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040 Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSA 770 GP P+ VPG P P GQ P ++ + G + P +P Y PG Sbjct: 1041 EGPPGPSGVPGQPGSPGLP-GQKGDKGDPGISSIGLPGLPG-PKGEPGLPGYPG-NPGIK 1097 Query: 771 LSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG--GYPRQPNYNALPNANYPSAGM 828 S P + G+ Q + + G GP+G G P P P G Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGH 1156 Query: 829 AGGINPMGAGGQMHGQPGIP-PYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPP- 886 G P G G+ GQ GIP P G G GN P P + + Q G G P Sbjct: 1157 PGQPGPPGEKGK-PGQDGIPGPAG--QKGEPGQPGFGN-PGPPGLPGLSGQKGDGGLPGI 1212 Query: 887 PGGMNRKTQETAVAMHVAANSIQN--RPPGYPNMNQGGMMGTGPPYG-QGINSMAGMINP 943 PG + H +Q PPG P G G P G G G+ P Sbjct: 1213 PGNPGLPGPKGEPGFH-GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGP 1271 Query: 944 QGPPYSMGGTMANNSAGMAASPEMMGLGDVK 974 +GPP G G P + GL +K Sbjct: 1272 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1302 Score = 73.2 bits (178), Expect = 3e-12 Identities = 222/979 (22%), Positives = 289/979 (29%), Gaps = 197/979 (20%) Query: 76 GAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133 G++ + G G G G PG E P L G GP PG G DG+ Sbjct: 35 GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGP-----------PGPRGQKGDDGIP 83 Query: 134 APPHSAAAALPPPAYGF-------GQP-YGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQ 185 PP PP GF G P + +P + G SPG LQ Sbjct: 84 GPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQ 143 Query: 186 SGGGG-GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGS--- 241 G G+ G + P + N YP P L P G PG Sbjct: 144 GPPGPPGIPGMKGEPGSIIMSSLPGPKGNP------GYPGPPGIQGLPGPTG-IPGPIGP 196 Query: 242 -GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 G G PP + +F + G G G G P P + + Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPK-GEKGEQGLQ----GPPGPPGQISEQKRPI 251 Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360 +G QG PG GP +GP G + + Sbjct: 252 DVEFQKGDQGLPG---DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308 Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420 P PG G G P P Q G P G G G + G PG Sbjct: 309 PGIPGLPGDPGYP--GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 421 PY--------GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472 P G Q P P G + + G +GP G G P + Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLD 425 Query: 473 QQSPHPQQQQPPYSQQP--PSQTPHAQPSYQQQPQSQPPQ-LQSSQ-------------- 515 Q P PP P P +P P S + LQ Q Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCI 485 Query: 516 -PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA-PSTL 573 S P QP P P S Q+ + Q + P+ P P P P + Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGL-PGIPGAPGAPGFPGSK 544 Query: 574 SQQA---AYPQPQSQQSQQTAYSQQRFPP-PQELSQDSFGSQASSAPSMTSSKGGQEDMN 629 + +P + + + + P P QD P + KG + Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL-------PGLPGPKGEPGGIT 597 Query: 630 LSLQSRPSSLPDLSGSIDDL-PMGTEGALSPG-VSTSGISSSQGEQSNPAQ--------S 679 + P P L G ++ PMG G PG V GI QG NP Q Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI---QGVAGNPGQPGIPGPKGD 654 Query: 680 PFSPHTSPHLPGIRGPS-----------------------PSPVGSPASVAQSRSGPLSP 716 P T P PG+ G P G P GP P Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP 714 Query: 717 AAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPR 774 PG PP P R ++ P P + P +PG AL P Sbjct: 715 KGFPGIPGPPGAPG----------------TPGRIGLEGPPGPPGFPGPKGEPGFAL-PG 757 Query: 775 QPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGI 832 P G+ ++ G+ GP+G G GP G P + + LP G G + Sbjct: 758 PPGP----PGLPGFK----GALGPKGDRGFPGPPGP-PGRTGLDGLP-------GPKGDV 801 Query: 833 NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGS-GMCPPPGGMN 891 P G G M G PG+P G P P +P +G G+ PG Sbjct: 802 GPNGQPGPM-GPPGLPGIGVQGP--------------PGPPGIPGPIGQPGLHGIPG--- 843 Query: 892 RKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMG 951 + PG P G+ GPP +G + G P GPP S G Sbjct: 844 -----------------EKGDPGPP-----GLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Query: 952 GTMANNSAGMAASPEMMGL 970 ++G + MG+ Sbjct: 882 LPGKAGASGFPGTKGEMGM 900 Score = 65.9 bits (159), Expect = 4e-10 Identities = 234/1043 (22%), Positives = 312/1043 (29%), Gaps = 218/1043 (20%) Query: 5 VAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVG 64 + P L PP PP K G E+GE Q +GP G Sbjct: 194 IGPPGPPGLMGPPGPPGLPGPKGNM-------GLNFQGPKGEKGE------QGLQGPP-G 239 Query: 65 PP-------QPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAGPRPA 112 PP +P+ E Q G + G G G G G PG E K G G R Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK 299 Query: 113 LNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172 PG G G+ P P Y G+P GR Sbjct: 300 --------PGKDGENGQPGIPGLPGD-------PGYP-GEP-GRDGEKGQKGDT------ 336 Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYP--PPAPAYA 230 G PGL + G G + G + N G P + +P P P P A Sbjct: 337 -GPPGPPGLVIPRPGTGITI----GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391 Query: 231 LSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG------ 284 + P G G G + PP S + GA G GP G Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG----QPGAPGLPGPPGPAGPHIPPS 447 Query: 285 ------GTPQPTATPTLNQLLTSPSSARGYQGYP-----GGDYSGGPQDGGAGKGPADMA 333 G P P +P ++ L +G +G G SG P G P Sbjct: 448 DEICEPGPPGPPGSPG-DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506 Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393 S + A A+G P PG+ G G P ++ +P + G + Sbjct: 507 SLGFPGQKGEKGQAGATG-----PKGLPGIPGAPGAPGFPGSKG-EPGDILTFPGMKGDK 560 Query: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453 G+ G P P Q G PG P P+ P + + + G +P Sbjct: 561 GELGSPGAPGLPGLPGTPGQD-GLPGLP----GPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 454 -YGQQGPSGYGQQGQTPYYNQQ--SPHPQQQQPPYSQQPPSQ--TPHAQPSYQQQPQSQP 508 G GP G+G G Q + +P Q P + P Q T +P P Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 509 PQLQSSQPPYSQQPSQP--PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ 566 P QP P P + P P+ P P Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG---------- 725 Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626 AP T + P FP P+ G+ Sbjct: 726 --APGTPGRIGLEGPP----------GPPGFPGPK----------------------GEP 751 Query: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG-----VSTSGISSSQGEQS-NPAQSP 680 L P LP G++ P G G P G+ +G+ N P Sbjct: 752 GFALPGPPGPPGLPGFKGALG--PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809 Query: 681 FSPHTSPHLPGI--RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH 738 P P LPGI +GP P P G P + Q +PG + P PP Sbjct: 810 MGP---PGLPGIGVQGP-PGPPGIPGPIGQP-----GLHGIPGEKGDPGPPG-------- 852 Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPRQPSGGQIHTGMGSYQQNSMGSY 796 ++ +RG +P +P P PGS P + G MG Sbjct: 853 --LDVPGPPGERG----SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE-----MGMM 901 Query: 797 GPQGGQYGPQGGYPRQPNYNALPNANYPSA--GMAGGINPMGAGGQMHGQPGIPPYGTLP 854 GP G GP G P + +P G G P G G G+PG+P P Sbjct: 902 GPPGPP-GPLG----IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK-GEPGLPG----P 951 Query: 855 PGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRP-- 912 PG P PN+ + G P G++ Q P Sbjct: 952 PG----------PMDPNLLGSKGEKGEPGLPGIPGVS------------GPKGYQGLPGD 989 Query: 913 PGYPNMN-QGGMMGT-GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 PG P ++ Q G+ G GP G+ G+I P G ++G G+ P G+ Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 971 GDVKLTPATKMNNKADGTPKTES 993 +P G P S Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISS 1072 Score = 36.2 bits (82), Expect = 0.38 Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 7/127 (5%) Query: 53 AAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPR 110 +AG E E +GPP P G G G G G G PG + P + G GP Sbjct: 1346 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1405 Query: 111 ----PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF-GQPYGRSPSAVAAAA 165 N L G GG G+ P + PP G G P S+VA Sbjct: 1406 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGF 1465 Query: 166 AAVFHQQ 172 H Q Sbjct: 1466 LITRHSQ 1472 Score = 34.3 bits (77), Expect = 1.4 Identities = 75/339 (22%), Positives = 105/339 (30%), Gaps = 50/339 (14%) Query: 1109 RGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAST 1168 +G PP I S P P G+ GP Q G + PP P Sbjct: 143 QGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202 Query: 1169 PHSQIPP-LPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPS-----MNTSDMMG 1222 PP LPG + + Q + + Q P P Q S ++ G Sbjct: 203 MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRPIDVEFQKG 258 Query: 1223 RMSYEPNKDPYG--SMRKAPGSDPFMSSGQGPNGGMGDPYSRA--------AGPGLGNVA 1272 ++ P G +R PG +G G G+P R PG+ + Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPP---GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315 Query: 1273 MGPRQHYPYGGPYDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQ 1331 P YP D + + G GP G P+P + + G P ++ ++ Sbjct: 316 GDP--GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373 Query: 1332 QQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNY--KRPMDGTYGPPAKRHEGEMY 1389 F P G P P M + +R G GPP Sbjct: 374 ----------GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-------I 416 Query: 1390 SVPYSTG-QGQPQQQQLP----PAQPQPASQQQAAQPSP 1423 S+P G GQP LP PA P + +P P Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455 Score = 31.6 bits (70), Expect = 9.4 Identities = 75/346 (21%), Positives = 109/346 (31%), Gaps = 56/346 (16%) Query: 1122 DSKKSQPKIQPPS----PAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPA----STP--HS 1171 D + QP + P+ G + GP P + ++G +P P S P + Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 1172 QIPPLPGM-SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNK 1230 +P PG S G+ + + + PG + ++ G E Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 1231 DPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAG----------PGLGNVAMGPRQHYP 1280 P G PG P G G GDP + G PGL P Sbjct: 1045 GPSG----VPGQ-PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGS 1099 Query: 1281 YGGP-------YDRVRTEPGI-------GPEGNMSTGAPQPNL-MPSNPD---SGMYSPS 1322 G P + +PG+ GP G P N +P P G + Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159 Query: 1323 RYPPQQQQQQQQRHDSYGNQFSTQGTPS----GSPFPSQQTTMYQQQQQNYKRPMDGTYG 1378 PP ++ + Q D +G P G+P P + Q+ + G G Sbjct: 1160 PGPPGEKGKPGQ--DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG 1217 Query: 1379 PPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424 P + E + P QG P PP P PA + P PQ Sbjct: 1218 LPGPKGEPGFHGFPGV--QGPPG----PPGSPGPALEGPKGNPGPQ 1257 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 102 bits (255), Expect = 3e-21 Identities = 224/949 (23%), Positives = 332/949 (34%), Gaps = 184/949 (19%) Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186 G +G+ PP P P Q GR P ++ QQ P Q Sbjct: 201 GKPEGIIKPPLQQQPPKPIPKQ---QGPGRDPLQQDGTPKSISSQQ------PEKIKSQP 251 Query: 187 GGGGGLEPYAGPQQNSH-DHGFPNHQYNSYYPNRS--------AYPPPAPAYALSSPRGG 237 G G +P GP Q DH Q ++ P + P P+ + + Sbjct: 252 PGTG--KPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309 Query: 238 TPGSGAAAAAG---SKPPPSSS-ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293 TPG A G S+P P+ A S + AQQ G P GT +P A P Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKPPAQP 365 Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA 353 P+ P +G + GP A A A Sbjct: 366 L------GPAK-------PPAQQTGSEKPSSEQPGPK----------ALAQPPGVGKTPA 402 Query: 354 QQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQ 413 QQ P P G +PLA+ P SP G T QQ GP P Q Sbjct: 403 QQPGPAKP--PTQQVGTPKPLAQQPGLQSPAKAPGP--------TKTPVQQPGPGKIPAQ 452 Query: 414 GHGYPGQPYGSQT-PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472 G PG+ QT P + P + G A+ PP Q GP+ + P Sbjct: 453 QAG-PGKTSAQQTGPTKPPSQLPGPAK------------PPPQQPGPA------KPPPQQ 493 Query: 473 QQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQ-SSQPPYSQQPS--QPPHQQ 529 S P QQP ++ PP Q A+PS QQ ++PP Q S P +QQPS +P QQ Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553 Query: 530 SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ---- 585 S P S T QPP P A+ P Q P+ P + + P+ Sbjct: 554 STKPV----SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609 Query: 586 --QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLS 643 + Q T S F P P +T K E + L+ Q + + L Sbjct: 610 CTECQTTVCSLCGFNPN---------------PHLTEVK---EWLCLNCQMKRA----LG 647 Query: 644 GSIDDLPMGTEGAL--SPGVSTSGISSS--QGEQSNPAQSP-----FSPHTSPHLPGIRG 694 G + +P + L +P +TS +S S Q +Q++P + S P P Sbjct: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707 Query: 695 PSPSPVGSPASVAQS--RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752 P+ GSP++ A+ + LS A PP+ PS S+ +++ +A D+ Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPA------PPKEPSVPSEQ------DKAPVADDK-- 753 Query: 753 MQRNPQMPQYSSPQPGSALSPRQPS--GGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYP 810 + P+M + ++ S+ + +P ++ + + + + Q P G Sbjct: 754 -PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK 812 Query: 811 RQP-NYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYG 869 P + A+P A + I+ G + GQ + P + + M +P Sbjct: 813 VSPFDSKAIPRP----ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868 Query: 870 ---PNMANMPP--QVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM 924 P + PP + +G P + K QE + + SI + P P Q + Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928 Query: 925 GTGPPYGQGINSMAGMI-----------------------NPQGPPYSMGGTMANNSAGM 961 G +G I S A + P PP S G + A Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP 988 Query: 962 AASPEMMGLGDVKLTPATKMNNKADGTP---KTESKSK----KSSSSTT 1003 A + + + K A K+ KA+ P +TE++ K K S S T Sbjct: 989 APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037 Score = 82.8 bits (203), Expect = 4e-15 Identities = 139/588 (23%), Positives = 196/588 (33%), Gaps = 88/588 (14%) Query: 338 GAAAAAAAAAAASGGAQ---------------QRSHHAPMSPGSSGGGGQPLARTPQPSS 382 G AAAAAA ASG Q S + Q L + P + Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPA 74 Query: 383 PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQ----RYPMTMQGRA 438 + R Q ++P Q PP G P QP S++ R + GR+ Sbjct: 75 AAESPSMHRKQELDSSHPPKQSGRPPDP-----GRPAQPGLSKSRTTDTFRSEQKLPGRS 129 Query: 439 QSAMG---GLSYTQQIPPYGQQGPSGYGQQ-----GQTPYYNQQSPHPQQQQPPYSQQPP 490 S + S T + G+ + + N+ +P SQ+ Sbjct: 130 PSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET 189 Query: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP-PHQQSPAPYPSQQ-----STTQQH 544 ++ Q +P+ +PP QQP +P P QQ P P QQ S + Q Sbjct: 190 TKKQKVVQKEQGKPEG------IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243 Query: 545 PQ---SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601 P+ SQPP + Q P Q Q A L + A+ PQ + + + P P Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDH-AKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302 Query: 602 E--LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD--LPMGTE--- 654 + + Q + G + P S+ G L G++ P GT Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP 362 Query: 655 ----GALSPGVSTSGISSSQGEQSNP---AQSPFSPHTSPHLPGIRGPSPSPVGSPASVA 707 G P +G EQ P AQ P T PG P VG+P +A Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422 Query: 708 QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP-- 765 Q + G SPA PG P G + + AQ G + Q+P + P Sbjct: 423 Q-QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481 Query: 766 -QPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNY--------- 815 QPG A P Q G GS P Q GP P+QP Sbjct: 482 QQPGPAKPPPQ------QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535 Query: 816 NALPNANYPSAGMAGG------INPMGAGGQMHGQPGIPPYGTLPPGR 857 +A P+A PS ++ G+G + P + P PP + Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ-PPTVSPSAKQPPSQ 582 Score = 81.3 bits (199), Expect = 1e-14 Identities = 106/418 (25%), Positives = 146/418 (34%), Gaps = 61/418 (14%) Query: 389 KMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448 K + +P G P QQQ P P+Q Q P R P+ G +S + Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQ-----------QGPGRDPLQQDGTPKSI------S 240 Query: 449 QQIPPYGQQGPSGYGQQGQTPYYNQQSPH-----------PQQQQPPY---SQQPPSQTP 494 Q P + P G G+ Q P Q+ H PQ +Q PS Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300 Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP-SQQSTTQQHPQSQPPYSQ 553 ++P QQ +PP Q P++PP Q S P +QQ T + P P ++ Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360 Query: 554 PQAQ------SPYQQ---QQP--QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602 P AQ P QQ ++P +QP P L+Q + +QQ Q+ P+ Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420 Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662 L+Q + AP T + Q P +P G P Sbjct: 421 LAQQPGLQSPAKAPGPTKTP--------VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472 Query: 663 TSGISSSQGEQSNPA----QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA 718 G + +Q PA Q P S PG P P G PA + + G P Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGSTKP-- 529 Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSS--IAQDRGYMQRNPQMPQYSSPQPGSALSPR 774 P Q PS Q S PS QS+ ++Q P S+ QP S P+ Sbjct: 530 -PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586 Score = 77.4 bits (189), Expect = 1e-13 Identities = 226/1083 (20%), Positives = 347/1083 (32%), Gaps = 199/1083 (18%) Query: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPA--PYPSQQSTT 541 P PP+ +Q+ S P QS +PP +P+QP +S + S+Q Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126 Query: 542 QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601 + P S + ++++ +++ P LS+ A S ++ P Sbjct: 127 GRSP-STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN---------PF 176 Query: 602 ELSQDSFGSQ--ASSAPSMTSSKGGQEDMNLS---LQSRPSSLPDLSGSIDDLPMGTEGA 656 +L DS SQ + + + G+ + + Q P +P G D P+ +G Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRD-PLQQDG- 234 Query: 657 LSPGVSTSGISSSQGEQ------------SNPAQSPFSPHTSPHL--------------- 689 + ISS Q E+ P Q+P + H L Sbjct: 235 -----TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV 289 Query: 690 ------PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743 P + PS P+ P P + PG PP PSG + Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT---------- 339 Query: 744 SSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG--PQGG 801 +AQ G ++ Q P + P P L P +P Q + S +Q + P G Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398 Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLP-----PG 856 + Q P +P + P A G +P A G P G +P PG Sbjct: 399 KTPAQQPGPAKPPTQQVGTPK-PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457 Query: 857 RMSHASMG-NRPYG--PNMANMPPQVGSGMCPP---PGGMNRKTQETAVAMHVAANSIQN 910 + S G +P P A PPQ PP PG +Q+ Q Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP----QQ 513 Query: 911 RPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP-EMMG 969 P P+ Q G T PP Q P + + A SA + P G Sbjct: 514 PGPAKPSPQQPG--STKPPSQQ---------PGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562 Query: 970 LGDVKLTPATKMNNK---ADGTPKTESK-----------SKKSSSSTTTNEKITKLYELG 1015 G P + K + G PKT +K++ +T T + T G Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622 Query: 1016 GEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRE 1075 P + TE K N + +GG + + Sbjct: 623 FNPNPHL--------TEVKEWLCLNCQ--------------MKRALGGDLAPVPSSPQPK 660 Query: 1076 LATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSP 1135 L T TS+ + SS + Q + ++ P D+ A + KK P ++ P+ Sbjct: 661 LKTAPVTTTSAVSKSSPQPQ--------QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712 Query: 1136 AGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ--------IPPLPGMSRSNSVGI 1187 GS S + Q P++ S S PP S P Q P P M + + + Sbjct: 713 HGSPSAKAKQPPEADSLSKP-----APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767 Query: 1188 QDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKD---PYGSMR-KAPGSD 1243 + + P + T S+ P + P+ S P SD Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827 Query: 1244 PFMSSGQGPNG-----GMGDPYSRAAGPGLGNVAMGPR---QHYPYGGPYDRVRTEPGIG 1295 + S GP+ DP + P M P+ + P G P T PG Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-----TPPGPR 882 Query: 1296 PEGNMSTGAPQPNLMPS--------NPDSGMYSPSRYPPQQQQQQQQRHDSYG------- 1340 P + PQ + P N S +P P Q+ + +G Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQA 942 Query: 1341 -NQFSTQGTP-----SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394 N ST G P SG P +Q Q + P PPA S+P Sbjct: 943 SNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK-----SIPVK 997 Query: 1395 TGQGQPQQQQL-PPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQN 1453 P ++L P A+ P ++ + P ++ A P A T+ + P++ Sbjct: 998 KETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057 Query: 1454 QFP 1456 P Sbjct: 1058 TCP 1060 Score = 63.9 bits (154), Expect = 2e-09 Identities = 100/412 (24%), Positives = 136/412 (33%), Gaps = 68/412 (16%) Query: 1237 RKAPGSDPFMSSGQGPNGGMGDPYS-RAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIG 1295 ++ PG DP G + P ++ PG G GP Q P Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQT-PQTDHAKLPLQRDASR 280 Query: 1296 PEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFP 1355 P+ + ++ PS P SPS+ P QQ + G++ S G P Sbjct: 281 PQTKQADIVRGESVKPSLP-----SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP 335 Query: 1356 SQQTTMYQQQQQNYKRPMD--GTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP---AQP 1410 S T QQ K P+ GT PPA+ G TG +P +Q P AQP Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALAQP 394 Query: 1411 QPASQQQAAQPSPQQDVYNQYGNAYP-ATATAATERRPAGGPQNQFPFQFGRDRVSA--- 1466 + A QP P + Q G P A A GP Q G ++ A Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454 Query: 1467 -PPGTNAQQN---MPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPA 1522 P T+AQQ PP + GP + Q G A P Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPP----------------------QQPGPAKPPPQ 492 Query: 1523 YHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHI 1582 G + G+ +PP P P + P S PPS Q Sbjct: 493 QPGSAKPPSQ--------------QPGSTKPPPQQPGPAKPSPQQPGST--KPPSQQ--- 533 Query: 1583 PQVSSP-APLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1633 P + P A P P + S P +G +G P+ ++P+ QPP Sbjct: 534 PGSAKPSAQQPSPAKPSAQQSTKPVSQTG-----SGKPLQPPTVSPSAKQPP 580 Score = 60.5 bits (145), Expect = 2e-08 Identities = 170/816 (20%), Positives = 268/816 (32%), Gaps = 151/816 (18%) Query: 12 SLGNPPPPP---PSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQE--SEGPAVGPP 66 SL +P PP P+ K QQ E A A+ + Q+ + P V PP Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356 Query: 67 -------QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTE 119 QPLG ++ G+E K S+ GP+ L + Sbjct: 357 GTTKPPAQPLGPAKPPAQQT---------------GSE---KPSSEQPGPKA-----LAQ 393 Query: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG--QPYGRSPSAVAAAAAAVFHQQHGGQQ 177 PPG VG P PP G +P + P + A A + Q Sbjct: 394 PPG---------VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444 Query: 178 SPG-LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG 236 PG + A Q+G G GP + S P + PP P A P+ Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPP-----------SQLPGPAKPPPQQPGPAKPPPQ- 492 Query: 237 GTPGSG---AAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293 PGS + +KPPP A S + + P +A QP+ Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ---QPGSAKPSAQQPSPAK 548 Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGP---QDGGAGKGPADMASQC-------------- 336 Q T P S G G P + P Q G P + C Sbjct: 549 PSAQQSTKPVSQTG-SGKPLQPPTVSPSAKQPPSQGL-PKTICPLCNTTELLLHVPEKAN 606 Query: 337 WGAAAAAAAAAAASGGAQQRSHHAPMS---------PGSSGGGGQPLARTPQPS------ 381 + + G H + + GG P+ +PQP Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQG--- 436 + + K PQP QQ P + P+Q +P + P T+ G Sbjct: 667 TTTSAVSKSSPQP--------QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP-TLHGSPS 717 Query: 437 -RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP------PYSQQP 489 +A+ S ++ PP + PS +Q + P + + P+ +P S Sbjct: 718 AKAKQPPEADSLSKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774 Query: 490 PSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPS---QPPHQQSPAPYPSQQSTTQQHP 545 P ++ Q + ++ PP + S++P S P+ P P P+ S HP Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834 Query: 546 -QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ--------QTAYSQQR 596 S Q Q ++++P++ + A P P+ + QT + Q+ Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894 Query: 597 FPPPQELSQD---SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGT 653 P PQE S+ + GS + S ++ QE + L +S+ + ++ + T Sbjct: 895 SPKPQEQSRRFSLNLGSITDAPKSQPTTP--QETVTGKLFGFGASIFSQASNL----IST 948 Query: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713 G PG + S G A +P P TS P G +P V + P Sbjct: 949 AG--QPGPHS---QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003 Query: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749 + P + P +++ P + S+ + Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039 Score = 58.9 bits (141), Expect = 5e-08 Identities = 85/383 (22%), Positives = 130/383 (33%), Gaps = 43/383 (11%) Query: 1110 GEDPPPDIFAAADSKKSQP---KIQPPSPAG--SGSMQGPQT-------------PQSTS 1151 G DP QP K QPP G Q PQT PQ+ Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285 Query: 1152 SSMAEGGDLKP--PTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNP 1209 + + G +KP P+P+ P Q P PG + G + + G + + +T Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQ--PTPGKPPAQQPGHEKS-QPGPAKPPAQPSGLTKPL 342 Query: 1210 GYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSG-QGPNGGMGDPYSRAAGPGL 1268 QP + + +P P G P P +G + P+ P + A PG+ Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLG-----PAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397 Query: 1269 GNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQ 1328 G +Q P P +V T + + + + A P P+ P + P QQ Sbjct: 398 GKTPA--QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQ 453 Query: 1329 QQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEM 1388 + G P + P QQ + Q G+ PP+++ G Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ-----PGSAKPPSQQ-PGST 507 Query: 1389 YSVPYSTGQGQPQQQQ----LPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATE 1444 P G +P QQ PP+Q +++ A QPSP + Q T + Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567 Query: 1445 RRPAGGPQNQFPFQFGRDRVSAP 1467 + P P + P G + P Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICP 590 Score = 54.3 bits (129), Expect = 1e-06 Identities = 123/545 (22%), Positives = 179/545 (32%), Gaps = 58/545 (10%) Query: 1131 QPPSPA------GSGSMQGPQTPQSTSSSMAEGGDLKPP-------TPASTP---HSQIP 1174 QPP P G +Q TP+S SS E +PP P TP H+++P Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP 273 Query: 1175 PLPGMSRSNSVGIQDAFNDGSDSTF---QKRNSMTPNPGYQPSMNTSDMMGRMS-YEPNK 1230 SR + + + K P PG P+ + +P Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA 333 Query: 1231 DPYG---SMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDR 1287 P G + + PG+ G P A P + P P GP Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP--GP-KA 390 Query: 1288 VRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347 + PG+G T A QP P+ P + + P QQ Q + G + Sbjct: 391 LAQPPGVG-----KTPAQQPG--PAKPPTQQVGTPK-PLAQQPGLQSPAKAPGPTKTPVQ 442 Query: 1348 TPSGSPFPSQQT--TMYQQQQQNYKRPMDGTYGP--PAKRHEGEMYSVPYSTGQGQPQQQ 1403 P P+QQ QQ +P GP P + G P G +P Q Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502 Query: 1404 QLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATER----RPAGGPQNQFPFQF 1459 Q P + P Q A+PSPQQ + + P +A + ++ +P+ + Q Sbjct: 503 Q-PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561 Query: 1460 GRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANR-QSTGSAP 1518 G + PP + PP G P + +N Q+T + Sbjct: 562 GSGKPLQPPTVSPSAKQPPS-QGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620 Query: 1519 QG--PAYHGVNRTDEMLHTD---QRANHEGSWPSHGTRQPPY--GPSAPVPPMTRPPPSN 1571 G P H + E L + +RA P + QP P +++ P Sbjct: 621 CGFNPNPH-LTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679 Query: 1572 YQPPPSMQNHIPQVSSPAPLPRPMENRTSP-SKSPFLHSGMKMQKAGPPVPASHIAPAPV 1630 Q P Q S AP P+ + P K P LH + PP S PAP Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPK----KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735 Query: 1631 QPPMI 1635 + P + Sbjct: 736 KEPSV 740 Score = 45.4 bits (106), Expect = 6e-04 Identities = 96/448 (21%), Positives = 148/448 (33%), Gaps = 67/448 (14%) Query: 1246 MSSGQG-PNGGMGDPYSRAAGPGLGNVAMGPRQHYPY--GGPYDRVR-TEPGIGPEGNMS 1301 MS QG P G + P + A P + H P G P D R +PG+ Sbjct: 60 MSRAQGLPKGSV--PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTD 117 Query: 1302 TGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRH--------------DSYGNQFSTQG 1347 T + L +P + S+ +++ + S N+F+ Sbjct: 118 TFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFD 177 Query: 1348 TPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQ--- 1404 S S ++TT Q+ Q + +G PP ++ + +P G G+ QQ Sbjct: 178 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK--PIPKQQGPGRDPLQQDGT 235 Query: 1405 ---LPPAQPQPASQQ--------QAAQPSPQQD---VYNQYGNAYPATATAATERRPAGG 1450 + QP+ Q Q +PQ D + Q + P T A R + Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK 295 Query: 1451 PQNQFPFQFGRDRVSAP---------PGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGR 1501 P P + + P PG Q P + P + +AQQ G Sbjct: 296 PSLPSP---SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ----PGT 348 Query: 1502 NDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPV 1561 + P GPA +T ++ + E P + P G + Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTG-----SEKPSSEQPGPKALAQPPGVGKTPAQ 403 Query: 1562 PPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPME---NRTSPSKSPFLHSG---MKMQK 1615 P PP+ P P + SPA P P + + P K P +G Q+ Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463 Query: 1616 AGPPVPASHIAPAPVQPPMIRRDITFPP 1643 GP P S + P P +PP + PP Sbjct: 464 TGPTKPPSQL-PGPAKPPPQQPGPAKPP 490 Score = 44.7 bits (104), Expect = 0.001 Identities = 183/939 (19%), Positives = 310/939 (33%), Gaps = 163/939 (17%) Query: 1113 PPPDIFAAADSKKSQP-KIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPT--PASTP 1169 PPP A QP +PPS + PQ P S + G KPP+ P S Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538 Query: 1170 HSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSM----------NTSD 1219 S P P + + GS Q +++P+ PS NT++ Sbjct: 539 PSAQQPSPAKPSAQQ-STKPVSQTGSGKPLQPP-TVSPSAKQPPSQGLPKTICPLCNTTE 596 Query: 1220 MMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD---------PYSRAAGPGLGN 1270 ++ + P K + + + + + G PN + + RA G L Sbjct: 597 LL---LHVPEKANFNTCTECQTTVCSLC-GFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652 Query: 1271 VAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQP-------NLMPSNPDSGMYSPSR 1323 V P+ +++T P + +S +PQP + P S P + Sbjct: 653 VPSSPQP---------KLKTAP-VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702 Query: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPM--DGTYGPPA 1381 PP +Q S + + P P ++ ++ +Q K P+ D P Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD---KAPVADDKPKQPKM 759 Query: 1382 KRHEGEMYS---------VPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYG 1432 + ++ S +P S Q Q +++ PP + A Q+ P+ ++ V Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-VSPFDS 818 Query: 1433 NAYPATATAATERRPAG------GPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486 A P A+ + G G + P Q + A + + + P G P Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878 Query: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQ---STGSAPQGPAYHGV----------------- 1526 T+ + +R+ + GS P Sbjct: 879 PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938 Query: 1527 -NRTDEMLHT-DQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIP- 1583 ++ ++ T Q H S P +Q P PS P P PP S Q PP+ IP Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAP-APSQP-PTSQGPPKSTGQAPPAPAKSIPV 996 Query: 1584 QVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPP 1643 + + AP +E + + + + +K PP+ S A Q ++ + P Sbjct: 997 KKETKAPAAEKLEPKAEQAPTV---KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Query: 1644 GSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMT 1703 E+T P+ K + KD P + K+ + ++ Sbjct: 1054 -KPESTCPLCKTELNIGSKD---PPNFNTCTECKNQVC------------------NLCG 1091 Query: 1704 FNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGE 1763 FN P L E+ C + G G + P +SP P+ Sbjct: 1092 FN--PTPHLTEIQEWLCLNCQTQ------RAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143 Query: 1764 EEEELLGP---KLEEEEEEEV--------VENDEEIAFSGKDKPASENSEEKLISKFDKL 1812 ++ P KL +++E+EV +E +E K P +++ SK +K Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKD 1203 Query: 1813 PVKIVQKNDPF-----------VVDCSDKLGRVQE-----FDSGLL-HWRIGGGDTTEH- 1854 +Q+ P + +K ++E D LL + + +H Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD 1263 Query: 1855 -IQTHFESKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRI------ 1907 +++ + E L R ++ T EG P T Q P D K I Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQP 1323 Query: 1908 --TATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGIS 1944 TA D + + T ED KS + + K P G+S Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDD-KSDTSSSQQPKSPQGLS 1361 Score = 44.3 bits (103), Expect = 0.001 Identities = 47/170 (27%), Positives = 61/170 (35%), Gaps = 30/170 (17%) Query: 408 PSGPQQGHGYPGQPYGSQTP--QRYPMTMQGRAQSAMGGLSYTQ---QIPPYGQQGPSGY 462 P+ + HG QT Q P Q +Q YTQ P Q P+ Y Sbjct: 3844 PTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSY 3903 Query: 463 GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522 QQ ++ QQ+ + QQ P YQ QP Q S P P Sbjct: 3904 TQQS---HFEQQTLYHQQVSP----------------YQTQPTFQAVATMSFTPQVQPTP 3944 Query: 523 SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ--QQQPQQPAP 570 + P Q PSQ QQ P+ Y +P+ S Y+ + QP AP Sbjct: 3945 TPQPSYQ----LPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAP 3990 Score = 41.2 bits (95), Expect = 0.012 Identities = 57/254 (22%), Positives = 90/254 (35%), Gaps = 26/254 (10%) Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546 ++P SQ P PS P P +SS S QP PP P P P P Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---------PP 2420 Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS-QQTAYSQQRFPPPQEL-- 603 PP P SP P++ A P + + + TA + P + Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480 Query: 604 -SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRP--SSLPDLSGSIDDL-PMGTEGALSP 659 + + SS PS E + +P LP + D+ P T +L+ Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540 Query: 660 GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG---------PSPSPVGSPASVAQSR 710 ++ + ++S+ + +P SP SPH++ P PS G+P + S+ Sbjct: 2541 SMTLNLVTSADYKLPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599 Query: 711 SGPLSPAAVPGNQM 724 + P P + Sbjct: 2600 AITSWPLGSPSKDL 2613 Score = 40.8 bits (94), Expect = 0.015 Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 25/234 (10%) Query: 364 PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG 423 P S G + + + P KM P+P P P P G P Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP----- 890 Query: 424 SQTPQRYPMTMQGRAQSAMGGLSYT---QQIPPYGQQGPSGYGQQGQTPYYNQQSP--HP 478 TPQ+ P + + ++ S T + P Q+ +G ++Q S Sbjct: 891 --TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948 Query: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ- 537 Q P+SQ P P+ Q P SQ P + Q P + S P +++ AP + Sbjct: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008 Query: 538 QSTTQQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584 + +Q P + +PP P S +PQ+ T +++ P+P+S Sbjct: 1009 EPKAEQAPTVKRTETEKKPP---PIKDSKSLTAEPQKAVLPTKLEKS--PKPES 1057 Score = 38.5 bits (88), Expect = 0.077 Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%) Query: 475 SPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPSQPPHQQSPAP 533 S P + + + + P P + S PQ+Q QL PY+Q P + AP Sbjct: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900 Query: 534 YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLS-----QQAAYPQPQSQQSQ 588 T Q H + Q Y Q SPY Q QP A +T+S Q PQP Q Sbjct: 3901 ---TSYTQQSHFEQQTLYHQQV--SPY-QTQPTFQAVATMSFTPQVQPTPTPQPSYQLPS 3954 Query: 589 QTAYSQQR 596 Q QQ+ Sbjct: 3955 QMMVIQQK 3962 Score = 38.1 bits (87), Expect = 0.100 Identities = 69/282 (24%), Positives = 113/282 (40%), Gaps = 41/282 (14%) Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQP 554 HA SY+ P+S+ + S+ +Q ++ Q PA Q+ + + P S+ Sbjct: 4150 HADTSYRHFPKSEKYSI--SRLTLEKQAAK----QLPAAILYQKQSKHKKSLIDPKMSK- 4202 Query: 555 QAQSPYQQQQPQQP------APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608 SP Q+ + +P ST S + + Q T ++ Q+ S Sbjct: 4203 --FSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260 Query: 609 GSQASS-APSMTSSKGGQEDMNLSL--QSRPSSLP------DLS----GSIDDLPMGTEG 655 G+ + ++ S+ + D S +SRPSS P DLS S L + + Sbjct: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320 Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP-----SPVGSPASVAQSR 710 A + VS S SSS ++ P P S + +P + S SPVG P +A++ Sbjct: 4321 AEALDVSFSHASSSA--RTKPTSLPIS-QSRGRIPIVAQNSEEESPLSPVGQPMGMARAA 4377 Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752 +GPL P + R G S S+ + ++ RGY Sbjct: 4378 AGPLPPISA-----DTRDQFGSSHSLPEVQQHMREESRTRGY 4414 Score = 35.0 bits (79), Expect = 0.85 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 6/98 (6%) Query: 520 QQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY 579 ++P P + P Q T Q PY+Q Q SP Q AP++ +QQ+ + Sbjct: 3854 ERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQ----APTSYTQQSHF 3909 Query: 580 PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPS 617 Q Q + Y Q P Q ++ SF Q P+ Sbjct: 3910 EQQTLYHQQVSPYQTQ--PTFQAVATMSFTPQVQPTPT 3945 Score = 34.3 bits (77), Expect = 1.4 Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 25/129 (19%) Query: 1552 QPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAP--LPRPMENRTSP--SKSPF- 1606 QPP P P PP PPP PPP +P +SP P LP+ SP + +P Sbjct: 2404 QPPPPPPPPPPPPPPPPPP--PPPP-----LPPPTSPKPTILPKKKLTVASPVTTATPLF 2456 Query: 1607 -----LHSGMKMQKAGPPVP---ASHIAPAPVQPPMIRRDITF-----PPGSVEATQPVL 1653 L + ++ G PV + P P +P I + F P A +PV+ Sbjct: 2457 DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVI 2516 Query: 1654 KQRRRLTMK 1662 Q T K Sbjct: 2517 PQLPTTTQK 2525 Score = 32.0 bits (71), Expect = 7.2 Identities = 42/188 (22%), Positives = 70/188 (37%), Gaps = 24/188 (12%) Query: 469 PYYNQQSPHPQQQQ--PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526 P ++ P P+ ++ P P + H + Q Q +L+ P + Q + P Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEEQKH--DLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291 Query: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQ 586 + + PQS P ++ +Q QP A + + Sbjct: 1292 QTK-------MEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDD 1344 Query: 587 SQQTAYSQQRFPPPQELSQDSFGSQASSA-----PSMTSS------KGGQEDMNLSLQSR 635 T+ SQQ PQ LS + S S+ PS+ + KG ++D + S +S Sbjct: 1345 KSDTSSSQQP-KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD-SFSQESS 1402 Query: 636 PSSLPDLS 643 PSS DL+ Sbjct: 1403 PSSPSDLA 1410 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 102 bits (255), Expect = 3e-21 Identities = 224/949 (23%), Positives = 332/949 (34%), Gaps = 184/949 (19%) Query: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186 G +G+ PP P P Q GR P ++ QQ P Q Sbjct: 201 GKPEGIIKPPLQQQPPKPIPKQ---QGPGRDPLQQDGTPKSISSQQ------PEKIKSQP 251 Query: 187 GGGGGLEPYAGPQQNSH-DHGFPNHQYNSYYPNRS--------AYPPPAPAYALSSPRGG 237 G G +P GP Q DH Q ++ P + P P+ + + Sbjct: 252 PGTG--KPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309 Query: 238 TPGSGAAAAAG---SKPPPSSS-ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293 TPG A G S+P P+ A S + AQQ G P GT +P A P Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKPPAQP 365 Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGA 353 P+ P +G + GP A A A Sbjct: 366 L------GPAK-------PPAQQTGSEKPSSEQPGPK----------ALAQPPGVGKTPA 402 Query: 354 QQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQ 413 QQ P P G +PLA+ P SP G T QQ GP P Q Sbjct: 403 QQPGPAKP--PTQQVGTPKPLAQQPGLQSPAKAPGP--------TKTPVQQPGPGKIPAQ 452 Query: 414 GHGYPGQPYGSQT-PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472 G PG+ QT P + P + G A+ PP Q GP+ + P Sbjct: 453 QAG-PGKTSAQQTGPTKPPSQLPGPAK------------PPPQQPGPA------KPPPQQ 493 Query: 473 QQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQ-SSQPPYSQQPS--QPPHQQ 529 S P QQP ++ PP Q A+PS QQ ++PP Q S P +QQPS +P QQ Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553 Query: 530 SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ---- 585 S P S T QPP P A+ P Q P+ P + + P+ Sbjct: 554 STKPV----SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609 Query: 586 --QSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLS 643 + Q T S F P P +T K E + L+ Q + + L Sbjct: 610 CTECQTTVCSLCGFNPN---------------PHLTEVK---EWLCLNCQMKRA----LG 647 Query: 644 GSIDDLPMGTEGAL--SPGVSTSGISSS--QGEQSNPAQSP-----FSPHTSPHLPGIRG 694 G + +P + L +P +TS +S S Q +Q++P + S P P Sbjct: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707 Query: 695 PSPSPVGSPASVAQS--RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752 P+ GSP++ A+ + LS A PP+ PS S+ +++ +A D+ Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPA------PPKEPSVPSEQ------DKAPVADDK-- 753 Query: 753 MQRNPQMPQYSSPQPGSALSPRQPS--GGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYP 810 + P+M + ++ S+ + +P ++ + + + + Q P G Sbjct: 754 -PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK 812 Query: 811 RQP-NYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYG 869 P + A+P A + I+ G + GQ + P + + M +P Sbjct: 813 VSPFDSKAIPRP----ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868 Query: 870 ---PNMANMPP--QVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM 924 P + PP + +G P + K QE + + SI + P P Q + Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928 Query: 925 GTGPPYGQGINSMAGMI-----------------------NPQGPPYSMGGTMANNSAGM 961 G +G I S A + P PP S G + A Sbjct: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP 988 Query: 962 AASPEMMGLGDVKLTPATKMNNKADGTP---KTESKSK----KSSSSTT 1003 A + + + K A K+ KA+ P +TE++ K K S S T Sbjct: 989 APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037 Score = 82.8 bits (203), Expect = 4e-15 Identities = 139/588 (23%), Positives = 196/588 (33%), Gaps = 88/588 (14%) Query: 338 GAAAAAAAAAAASGGAQ---------------QRSHHAPMSPGSSGGGGQPLARTPQPSS 382 G AAAAAA ASG Q S + Q L + P + Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPA 74 Query: 383 PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQ----RYPMTMQGRA 438 + R Q ++P Q PP G P QP S++ R + GR+ Sbjct: 75 AAESPSMHRKQELDSSHPPKQSGRPPDP-----GRPAQPGLSKSRTTDTFRSEQKLPGRS 129 Query: 439 QSAMG---GLSYTQQIPPYGQQGPSGYGQQ-----GQTPYYNQQSPHPQQQQPPYSQQPP 490 S + S T + G+ + + N+ +P SQ+ Sbjct: 130 PSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET 189 Query: 491 SQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP-PHQQSPAPYPSQQ-----STTQQH 544 ++ Q +P+ +PP QQP +P P QQ P P QQ S + Q Sbjct: 190 TKKQKVVQKEQGKPEG------IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243 Query: 545 PQ---SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601 P+ SQPP + Q P Q Q A L + A+ PQ + + + P P Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDH-AKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302 Query: 602 E--LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD--LPMGTE--- 654 + + Q + G + P S+ G L G++ P GT Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP 362 Query: 655 ----GALSPGVSTSGISSSQGEQSNP---AQSPFSPHTSPHLPGIRGPSPSPVGSPASVA 707 G P +G EQ P AQ P T PG P VG+P +A Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422 Query: 708 QSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP-- 765 Q + G SPA PG P G + + AQ G + Q+P + P Sbjct: 423 Q-QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481 Query: 766 -QPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNY--------- 815 QPG A P Q G GS P Q GP P+QP Sbjct: 482 QQPGPAKPPPQ------QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535 Query: 816 NALPNANYPSAGMAGG------INPMGAGGQMHGQPGIPPYGTLPPGR 857 +A P+A PS ++ G+G + P + P PP + Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ-PPTVSPSAKQPPSQ 582 Score = 81.3 bits (199), Expect = 1e-14 Identities = 106/418 (25%), Positives = 146/418 (34%), Gaps = 61/418 (14%) Query: 389 KMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448 K + +P G P QQQ P P+Q Q P R P+ G +S + Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQ-----------QGPGRDPLQQDGTPKSI------S 240 Query: 449 QQIPPYGQQGPSGYGQQGQTPYYNQQSPH-----------PQQQQPPY---SQQPPSQTP 494 Q P + P G G+ Q P Q+ H PQ +Q PS Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300 Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP-SQQSTTQQHPQSQPPYSQ 553 ++P QQ +PP Q P++PP Q S P +QQ T + P P ++ Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360 Query: 554 PQAQ------SPYQQ---QQP--QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE 602 P AQ P QQ ++P +QP P L+Q + +QQ Q+ P+ Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420 Query: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662 L+Q + AP T + Q P +P G P Sbjct: 421 LAQQPGLQSPAKAPGPTKTP--------VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472 Query: 663 TSGISSSQGEQSNPA----QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA 718 G + +Q PA Q P S PG P P G PA + + G P Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGSTKP-- 529 Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSS--IAQDRGYMQRNPQMPQYSSPQPGSALSPR 774 P Q PS Q S PS QS+ ++Q P S+ QP S P+ Sbjct: 530 -PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586 Score = 77.4 bits (189), Expect = 1e-13 Identities = 226/1083 (20%), Positives = 347/1083 (32%), Gaps = 199/1083 (18%) Query: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPA--PYPSQQSTT 541 P PP+ +Q+ S P QS +PP +P+QP +S + S+Q Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126 Query: 542 QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601 + P S + ++++ +++ P LS+ A S ++ P Sbjct: 127 GRSP-STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN---------PF 176 Query: 602 ELSQDSFGSQ--ASSAPSMTSSKGGQEDMNLS---LQSRPSSLPDLSGSIDDLPMGTEGA 656 +L DS SQ + + + G+ + + Q P +P G D P+ +G Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRD-PLQQDG- 234 Query: 657 LSPGVSTSGISSSQGEQ------------SNPAQSPFSPHTSPHL--------------- 689 + ISS Q E+ P Q+P + H L Sbjct: 235 -----TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV 289 Query: 690 ------PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQ 743 P + PS P+ P P + PG PP PSG + Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT---------- 339 Query: 744 SSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG--PQGG 801 +AQ G ++ Q P + P P L P +P Q + S +Q + P G Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398 Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLP-----PG 856 + Q P +P + P A G +P A G P G +P PG Sbjct: 399 KTPAQQPGPAKPPTQQVGTPK-PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457 Query: 857 RMSHASMG-NRPYG--PNMANMPPQVGSGMCPP---PGGMNRKTQETAVAMHVAANSIQN 910 + S G +P P A PPQ PP PG +Q+ Q Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP----QQ 513 Query: 911 RPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASP-EMMG 969 P P+ Q G T PP Q P + + A SA + P G Sbjct: 514 PGPAKPSPQQPG--STKPPSQQ---------PGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562 Query: 970 LGDVKLTPATKMNNK---ADGTPKTESK-----------SKKSSSSTTTNEKITKLYELG 1015 G P + K + G PKT +K++ +T T + T G Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622 Query: 1016 GEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRE 1075 P + TE K N + +GG + + Sbjct: 623 FNPNPHL--------TEVKEWLCLNCQ--------------MKRALGGDLAPVPSSPQPK 660 Query: 1076 LATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSP 1135 L T TS+ + SS + Q + ++ P D+ A + KK P ++ P+ Sbjct: 661 LKTAPVTTTSAVSKSSPQPQ--------QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712 Query: 1136 AGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ--------IPPLPGMSRSNSVGI 1187 GS S + Q P++ S S PP S P Q P P M + + + Sbjct: 713 HGSPSAKAKQPPEADSLSKP-----APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767 Query: 1188 QDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKD---PYGSMR-KAPGSD 1243 + + P + T S+ P + P+ S P SD Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827 Query: 1244 PFMSSGQGPNG-----GMGDPYSRAAGPGLGNVAMGPR---QHYPYGGPYDRVRTEPGIG 1295 + S GP+ DP + P M P+ + P G P T PG Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-----TPPGPR 882 Query: 1296 PEGNMSTGAPQPNLMPS--------NPDSGMYSPSRYPPQQQQQQQQRHDSYG------- 1340 P + PQ + P N S +P P Q+ + +G Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQA 942 Query: 1341 -NQFSTQGTP-----SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394 N ST G P SG P +Q Q + P PPA S+P Sbjct: 943 SNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK-----SIPVK 997 Query: 1395 TGQGQPQQQQL-PPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQN 1453 P ++L P A+ P ++ + P ++ A P A T+ + P++ Sbjct: 998 KETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057 Query: 1454 QFP 1456 P Sbjct: 1058 TCP 1060 Score = 63.9 bits (154), Expect = 2e-09 Identities = 100/412 (24%), Positives = 136/412 (33%), Gaps = 68/412 (16%) Query: 1237 RKAPGSDPFMSSGQGPNGGMGDPYS-RAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIG 1295 ++ PG DP G + P ++ PG G GP Q P Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQT-PQTDHAKLPLQRDASR 280 Query: 1296 PEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFP 1355 P+ + ++ PS P SPS+ P QQ + G++ S G P Sbjct: 281 PQTKQADIVRGESVKPSLP-----SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP 335 Query: 1356 SQQTTMYQQQQQNYKRPMD--GTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP---AQP 1410 S T QQ K P+ GT PPA+ G TG +P +Q P AQP Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALAQP 394 Query: 1411 QPASQQQAAQPSPQQDVYNQYGNAYP-ATATAATERRPAGGPQNQFPFQFGRDRVSA--- 1466 + A QP P + Q G P A A GP Q G ++ A Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454 Query: 1467 -PPGTNAQQN---MPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPA 1522 P T+AQQ PP + GP + Q G A P Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPP----------------------QQPGPAKPPPQ 492 Query: 1523 YHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHI 1582 G + G+ +PP P P + P S PPS Q Sbjct: 493 QPGSAKPPSQ--------------QPGSTKPPPQQPGPAKPSPQQPGST--KPPSQQ--- 533 Query: 1583 PQVSSP-APLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1633 P + P A P P + S P +G +G P+ ++P+ QPP Sbjct: 534 PGSAKPSAQQPSPAKPSAQQSTKPVSQTG-----SGKPLQPPTVSPSAKQPP 580 Score = 60.5 bits (145), Expect = 2e-08 Identities = 170/816 (20%), Positives = 268/816 (32%), Gaps = 151/816 (18%) Query: 12 SLGNPPPPP---PSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQE--SEGPAVGPP 66 SL +P PP P+ K QQ E A A+ + Q+ + P V PP Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356 Query: 67 -------QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTE 119 QPLG ++ G+E K S+ GP+ L + Sbjct: 357 GTTKPPAQPLGPAKPPAQQT---------------GSE---KPSSEQPGPKA-----LAQ 393 Query: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG--QPYGRSPSAVAAAAAAVFHQQHGGQQ 177 PPG VG P PP G +P + P + A A + Q Sbjct: 394 PPG---------VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444 Query: 178 SPG-LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG 236 PG + A Q+G G GP + S P + PP P A P+ Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPP-----------SQLPGPAKPPPQQPGPAKPPPQ- 492 Query: 237 GTPGSG---AAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP 293 PGS + +KPPP A S + + P +A QP+ Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ---QPGSAKPSAQQPSPAK 548 Query: 294 TLNQLLTSPSSARGYQGYPGGDYSGGP---QDGGAGKGPADMASQC-------------- 336 Q T P S G G P + P Q G P + C Sbjct: 549 PSAQQSTKPVSQTG-SGKPLQPPTVSPSAKQPPSQGL-PKTICPLCNTTELLLHVPEKAN 606 Query: 337 WGAAAAAAAAAAASGGAQQRSHHAPMS---------PGSSGGGGQPLARTPQPS------ 381 + + G H + + GG P+ +PQP Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGP--PSGPQQGHGYPGQPYGSQTPQRYPMTMQG--- 436 + + K PQP QQ P + P+Q +P + P T+ G Sbjct: 667 TTTSAVSKSSPQP--------QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP-TLHGSPS 717 Query: 437 -RAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQP------PYSQQP 489 +A+ S ++ PP + PS +Q + P + + P+ +P S Sbjct: 718 AKAKQPPEADSLSKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774 Query: 490 PSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPS---QPPHQQSPAPYPSQQSTTQQHP 545 P ++ Q + ++ PP + S++P S P+ P P P+ S HP Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834 Query: 546 -QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ--------QTAYSQQR 596 S Q Q ++++P++ + A P P+ + QT + Q+ Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894 Query: 597 FPPPQELSQD---SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGT 653 P PQE S+ + GS + S ++ QE + L +S+ + ++ + T Sbjct: 895 SPKPQEQSRRFSLNLGSITDAPKSQPTTP--QETVTGKLFGFGASIFSQASNL----IST 948 Query: 654 EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP 713 G PG + S G A +P P TS P G +P V + P Sbjct: 949 AG--QPGPHS---QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003 Query: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749 + P + P +++ P + S+ + Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039 Score = 58.9 bits (141), Expect = 5e-08 Identities = 85/383 (22%), Positives = 130/383 (33%), Gaps = 43/383 (11%) Query: 1110 GEDPPPDIFAAADSKKSQP---KIQPPSPAG--SGSMQGPQT-------------PQSTS 1151 G DP QP K QPP G Q PQT PQ+ Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285 Query: 1152 SSMAEGGDLKP--PTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNP 1209 + + G +KP P+P+ P Q P PG + G + + G + + +T Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQ--PTPGKPPAQQPGHEKS-QPGPAKPPAQPSGLTKPL 342 Query: 1210 GYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSG-QGPNGGMGDPYSRAAGPGL 1268 QP + + +P P G P P +G + P+ P + A PG+ Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLG-----PAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397 Query: 1269 GNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQ 1328 G +Q P P +V T + + + + A P P+ P + P QQ Sbjct: 398 GKTPA--QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQ 453 Query: 1329 QQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEM 1388 + G P + P QQ + Q G+ PP+++ G Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQ-----PGSAKPPSQQ-PGST 507 Query: 1389 YSVPYSTGQGQPQQQQ----LPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATE 1444 P G +P QQ PP+Q +++ A QPSP + Q T + Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567 Query: 1445 RRPAGGPQNQFPFQFGRDRVSAP 1467 + P P + P G + P Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICP 590 Score = 54.3 bits (129), Expect = 1e-06 Identities = 123/545 (22%), Positives = 179/545 (32%), Gaps = 58/545 (10%) Query: 1131 QPPSPA------GSGSMQGPQTPQSTSSSMAEGGDLKPP-------TPASTP---HSQIP 1174 QPP P G +Q TP+S SS E +PP P TP H+++P Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP 273 Query: 1175 PLPGMSRSNSVGIQDAFNDGSDSTF---QKRNSMTPNPGYQPSMNTSDMMGRMS-YEPNK 1230 SR + + + K P PG P+ + +P Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA 333 Query: 1231 DPYG---SMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDR 1287 P G + + PG+ G P A P + P P GP Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP--GP-KA 390 Query: 1288 VRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347 + PG+G T A QP P+ P + + P QQ Q + G + Sbjct: 391 LAQPPGVG-----KTPAQQPG--PAKPPTQQVGTPK-PLAQQPGLQSPAKAPGPTKTPVQ 442 Query: 1348 TPSGSPFPSQQT--TMYQQQQQNYKRPMDGTYGP--PAKRHEGEMYSVPYSTGQGQPQQQ 1403 P P+QQ QQ +P GP P + G P G +P Q Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502 Query: 1404 QLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATER----RPAGGPQNQFPFQF 1459 Q P + P Q A+PSPQQ + + P +A + ++ +P+ + Q Sbjct: 503 Q-PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561 Query: 1460 GRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANR-QSTGSAP 1518 G + PP + PP G P + +N Q+T + Sbjct: 562 GSGKPLQPPTVSPSAKQPPS-QGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620 Query: 1519 QG--PAYHGVNRTDEMLHTD---QRANHEGSWPSHGTRQPPY--GPSAPVPPMTRPPPSN 1571 G P H + E L + +RA P + QP P +++ P Sbjct: 621 CGFNPNPH-LTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679 Query: 1572 YQPPPSMQNHIPQVSSPAPLPRPMENRTSP-SKSPFLHSGMKMQKAGPPVPASHIAPAPV 1630 Q P Q S AP P+ + P K P LH + PP S PAP Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPK----KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735 Query: 1631 QPPMI 1635 + P + Sbjct: 736 KEPSV 740 Score = 45.4 bits (106), Expect = 6e-04 Identities = 96/448 (21%), Positives = 148/448 (33%), Gaps = 67/448 (14%) Query: 1246 MSSGQG-PNGGMGDPYSRAAGPGLGNVAMGPRQHYPY--GGPYDRVR-TEPGIGPEGNMS 1301 MS QG P G + P + A P + H P G P D R +PG+ Sbjct: 60 MSRAQGLPKGSV--PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTD 117 Query: 1302 TGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRH--------------DSYGNQFSTQG 1347 T + L +P + S+ +++ + S N+F+ Sbjct: 118 TFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFD 177 Query: 1348 TPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQ--- 1404 S S ++TT Q+ Q + +G PP ++ + +P G G+ QQ Sbjct: 178 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK--PIPKQQGPGRDPLQQDGT 235 Query: 1405 ---LPPAQPQPASQQ--------QAAQPSPQQD---VYNQYGNAYPATATAATERRPAGG 1450 + QP+ Q Q +PQ D + Q + P T A R + Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK 295 Query: 1451 PQNQFPFQFGRDRVSAP---------PGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGR 1501 P P + + P PG Q P + P + +AQQ G Sbjct: 296 PSLPSP---SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ----PGT 348 Query: 1502 NDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPV 1561 + P GPA +T ++ + E P + P G + Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTG-----SEKPSSEQPGPKALAQPPGVGKTPAQ 403 Query: 1562 PPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPME---NRTSPSKSPFLHSG---MKMQK 1615 P PP+ P P + SPA P P + + P K P +G Q+ Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463 Query: 1616 AGPPVPASHIAPAPVQPPMIRRDITFPP 1643 GP P S + P P +PP + PP Sbjct: 464 TGPTKPPSQL-PGPAKPPPQQPGPAKPP 490 Score = 44.7 bits (104), Expect = 0.001 Identities = 183/939 (19%), Positives = 310/939 (33%), Gaps = 163/939 (17%) Query: 1113 PPPDIFAAADSKKSQP-KIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPT--PASTP 1169 PPP A QP +PPS + PQ P S + G KPP+ P S Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538 Query: 1170 HSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSM----------NTSD 1219 S P P + + GS Q +++P+ PS NT++ Sbjct: 539 PSAQQPSPAKPSAQQ-STKPVSQTGSGKPLQPP-TVSPSAKQPPSQGLPKTICPLCNTTE 596 Query: 1220 MMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD---------PYSRAAGPGLGN 1270 ++ + P K + + + + + G PN + + RA G L Sbjct: 597 LL---LHVPEKANFNTCTECQTTVCSLC-GFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652 Query: 1271 VAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQP-------NLMPSNPDSGMYSPSR 1323 V P+ +++T P + +S +PQP + P S P + Sbjct: 653 VPSSPQP---------KLKTAP-VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702 Query: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPM--DGTYGPPA 1381 PP +Q S + + P P ++ ++ +Q K P+ D P Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD---KAPVADDKPKQPKM 759 Query: 1382 KRHEGEMYS---------VPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYG 1432 + ++ S +P S Q Q +++ PP + A Q+ P+ ++ V Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-VSPFDS 818 Query: 1433 NAYPATATAATERRPAG------GPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486 A P A+ + G G + P Q + A + + + P G P Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878 Query: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQ---STGSAPQGPAYHGV----------------- 1526 T+ + +R+ + GS P Sbjct: 879 PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938 Query: 1527 -NRTDEMLHT-DQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIP- 1583 ++ ++ T Q H S P +Q P PS P P PP S Q PP+ IP Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAP-APSQP-PTSQGPPKSTGQAPPAPAKSIPV 996 Query: 1584 QVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPP 1643 + + AP +E + + + + +K PP+ S A Q ++ + P Sbjct: 997 KKETKAPAAEKLEPKAEQAPTV---KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Query: 1644 GSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMT 1703 E+T P+ K + KD P + K+ + ++ Sbjct: 1054 -KPESTCPLCKTELNIGSKD---PPNFNTCTECKNQVC------------------NLCG 1091 Query: 1704 FNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGE 1763 FN P L E+ C + G G + P +SP P+ Sbjct: 1092 FN--PTPHLTEIQEWLCLNCQTQ------RAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143 Query: 1764 EEEELLGP---KLEEEEEEEV--------VENDEEIAFSGKDKPASENSEEKLISKFDKL 1812 ++ P KL +++E+EV +E +E K P +++ SK +K Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKD 1203 Query: 1813 PVKIVQKNDPF-----------VVDCSDKLGRVQE-----FDSGLL-HWRIGGGDTTEH- 1854 +Q+ P + +K ++E D LL + + +H Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD 1263 Query: 1855 -IQTHFESKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRI------ 1907 +++ + E L R ++ T EG P T Q P D K I Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQP 1323 Query: 1908 --TATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGIS 1944 TA D + + T ED KS + + K P G+S Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDD-KSDTSSSQQPKSPQGLS 1361 Score = 44.3 bits (103), Expect = 0.001 Identities = 47/170 (27%), Positives = 61/170 (35%), Gaps = 30/170 (17%) Query: 408 PSGPQQGHGYPGQPYGSQTP--QRYPMTMQGRAQSAMGGLSYTQ---QIPPYGQQGPSGY 462 P+ + HG QT Q P Q +Q YTQ P Q P+ Y Sbjct: 3844 PTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSY 3903 Query: 463 GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522 QQ ++ QQ+ + QQ P YQ QP Q S P P Sbjct: 3904 TQQS---HFEQQTLYHQQVSP----------------YQTQPTFQAVATMSFTPQVQPTP 3944 Query: 523 SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ--QQQPQQPAP 570 + P Q PSQ QQ P+ Y +P+ S Y+ + QP AP Sbjct: 3945 TPQPSYQ----LPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAP 3990 Score = 41.2 bits (95), Expect = 0.012 Identities = 57/254 (22%), Positives = 90/254 (35%), Gaps = 26/254 (10%) Query: 487 QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQ 546 ++P SQ P PS P P +SS S QP PP P P P P Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---------PP 2420 Query: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS-QQTAYSQQRFPPPQEL-- 603 PP P SP P++ A P + + + TA + P + Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480 Query: 604 -SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRP--SSLPDLSGSIDDL-PMGTEGALSP 659 + + SS PS E + +P LP + D+ P T +L+ Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540 Query: 660 GVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG---------PSPSPVGSPASVAQSR 710 ++ + ++S+ + +P SP SPH++ P PS G+P + S+ Sbjct: 2541 SMTLNLVTSADYKLPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599 Query: 711 SGPLSPAAVPGNQM 724 + P P + Sbjct: 2600 AITSWPLGSPSKDL 2613 Score = 40.8 bits (94), Expect = 0.015 Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 25/234 (10%) Query: 364 PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG 423 P S G + + + P KM P+P P P P G P Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP----- 890 Query: 424 SQTPQRYPMTMQGRAQSAMGGLSYT---QQIPPYGQQGPSGYGQQGQTPYYNQQSP--HP 478 TPQ+ P + + ++ S T + P Q+ +G ++Q S Sbjct: 891 --TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948 Query: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ- 537 Q P+SQ P P+ Q P SQ P + Q P + S P +++ AP + Sbjct: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008 Query: 538 QSTTQQHP-------QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQS 584 + +Q P + +PP P S +PQ+ T +++ P+P+S Sbjct: 1009 EPKAEQAPTVKRTETEKKPP---PIKDSKSLTAEPQKAVLPTKLEKS--PKPES 1057 Score = 38.5 bits (88), Expect = 0.077 Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%) Query: 475 SPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPP-QLQSSQPPYSQQPSQPPHQQSPAP 533 S P + + + + P P + S PQ+Q QL PY+Q P + AP Sbjct: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900 Query: 534 YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLS-----QQAAYPQPQSQQSQ 588 T Q H + Q Y Q SPY Q QP A +T+S Q PQP Q Sbjct: 3901 ---TSYTQQSHFEQQTLYHQQV--SPY-QTQPTFQAVATMSFTPQVQPTPTPQPSYQLPS 3954 Query: 589 QTAYSQQR 596 Q QQ+ Sbjct: 3955 QMMVIQQK 3962 Score = 38.1 bits (87), Expect = 0.100 Identities = 69/282 (24%), Positives = 113/282 (40%), Gaps = 41/282 (14%) Query: 495 HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQP 554 HA SY+ P+S+ + S+ +Q ++ Q PA Q+ + + P S+ Sbjct: 4150 HADTSYRHFPKSEKYSI--SRLTLEKQAAK----QLPAAILYQKQSKHKKSLIDPKMSK- 4202 Query: 555 QAQSPYQQQQPQQP------APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608 SP Q+ + +P ST S + + Q T ++ Q+ S Sbjct: 4203 --FSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260 Query: 609 GSQASS-APSMTSSKGGQEDMNLSL--QSRPSSLP------DLS----GSIDDLPMGTEG 655 G+ + ++ S+ + D S +SRPSS P DLS S L + + Sbjct: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320 Query: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP-----SPVGSPASVAQSR 710 A + VS S SSS ++ P P S + +P + S SPVG P +A++ Sbjct: 4321 AEALDVSFSHASSSA--RTKPTSLPIS-QSRGRIPIVAQNSEEESPLSPVGQPMGMARAA 4377 Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGY 752 +GPL P + R G S S+ + ++ RGY Sbjct: 4378 AGPLPPISA-----DTRDQFGSSHSLPEVQQHMREESRTRGY 4414 Score = 35.0 bits (79), Expect = 0.85 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 6/98 (6%) Query: 520 QQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY 579 ++P P + P Q T Q PY+Q Q SP Q AP++ +QQ+ + Sbjct: 3854 ERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQ----APTSYTQQSHF 3909 Query: 580 PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPS 617 Q Q + Y Q P Q ++ SF Q P+ Sbjct: 3910 EQQTLYHQQVSPYQTQ--PTFQAVATMSFTPQVQPTPT 3945 Score = 34.3 bits (77), Expect = 1.4 Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 25/129 (19%) Query: 1552 QPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAP--LPRPMENRTSP--SKSPF- 1606 QPP P P PP PPP PPP +P +SP P LP+ SP + +P Sbjct: 2404 QPPPPPPPPPPPPPPPPPP--PPPP-----LPPPTSPKPTILPKKKLTVASPVTTATPLF 2456 Query: 1607 -----LHSGMKMQKAGPPVP---ASHIAPAPVQPPMIRRDITF-----PPGSVEATQPVL 1653 L + ++ G PV + P P +P I + F P A +PV+ Sbjct: 2457 DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVI 2516 Query: 1654 KQRRRLTMK 1662 Q T K Sbjct: 2517 PQLPTTTQK 2525 Score = 32.0 bits (71), Expect = 7.2 Identities = 42/188 (22%), Positives = 70/188 (37%), Gaps = 24/188 (12%) Query: 469 PYYNQQSPHPQQQQ--PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526 P ++ P P+ ++ P P + H + Q Q +L+ P + Q + P Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEEQKH--DLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291 Query: 527 HQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQ 586 + + PQS P ++ +Q QP A + + Sbjct: 1292 QTK-------MEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDD 1344 Query: 587 SQQTAYSQQRFPPPQELSQDSFGSQASSA-----PSMTSS------KGGQEDMNLSLQSR 635 T+ SQQ PQ LS + S S+ PS+ + KG ++D + S +S Sbjct: 1345 KSDTSSSQQP-KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD-SFSQESS 1402 Query: 636 PSSLPDLS 643 PSS DL+ Sbjct: 1403 PSSPSDLA 1410 >gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein [Homo sapiens] Length = 593 Score = 102 bits (254), Expect = 4e-21 Identities = 66/194 (34%), Positives = 104/194 (53%), Gaps = 21/194 (10%) Query: 1003 TTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIG 1062 T E+ +LYEL G+P+RK ++D +F +++ + +P + ++ LDL+ LYV V E G Sbjct: 224 TYEEQFKQLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKG 283 Query: 1063 GLTQVNKNKKWRELATNLNVGTS-SSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAA 1121 GL +V K WRE+ LN+ TS +SAA +L+ QY++ LY +EC+ +RG P ++ AA Sbjct: 284 GLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECE-KRGLSNPNELQAAI 342 Query: 1122 DSKKSQPKIQ-------PPSPAGS-GSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI 1173 DS + + + Q SP G+ G + P+ P S+ AST S I Sbjct: 343 DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLG-----------LAASTNGSSI 391 Query: 1174 PPLPGMSRSNSVGI 1187 P P + + I Sbjct: 392 TPAPKIKKEEDSAI 405 Score = 38.1 bits (87), Expect = 0.100 Identities = 45/197 (22%), Positives = 63/197 (31%), Gaps = 10/197 (5%) Query: 15 NPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ--PLGKE 72 +PP PP + A + RE A A M+AAA + G + P G E Sbjct: 30 DPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASPGGSEDGPPGSE 89 Query: 73 LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR---PALNNNLTEPPGGGGGGSS 129 +D A G G G G D+ S+ + P+ + +L E Sbjct: 90 EEDAAREGTPGSPGRGREGPGEEHFEDMA-SDEDMKPKWEEEEMEEDLGEDEEEEEEDYE 148 Query: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189 D P + G + R A + GGQ+ PG GG Sbjct: 149 DEEEEEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGVPRVLGGQERPGPGPAHPGGA 208 Query: 190 GGLEPYAGPQQNSHDHG 206 + PQ DHG Sbjct: 209 A----HVAPQLQPPDHG 221 Score = 32.7 bits (73), Expect = 4.2 Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 5/45 (11%) Query: 65 PPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGP 109 PP P A + GGGGGGG+ S G G + S G AGP Sbjct: 538 PPAPT----PTSAPNKGGGGGGGSSSNAG-GRGGNTGTSGGQAGP 577 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 102 bits (253), Expect = 6e-21 Identities = 244/1052 (23%), Positives = 312/1052 (29%), Gaps = 206/1052 (19%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERG-----EMKAAAGQESEGP 61 P + PP P K+ G A +RG + G E Sbjct: 572 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 631 Query: 62 AVGPPQPLGKELQDGAESNGGGGG--GGAGSGG--GPGAEPDLKNSNGNAGPRPALNNNL 117 GPP P G + G + G G G AG G GP P G AG + Sbjct: 632 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG--------V 683 Query: 118 TEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173 PPG G G PP + LP P G P + P Sbjct: 684 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP--------------- 728 Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF---PNHQYNSYYPNRSAYPPPAPAYA 230 Q PGLA L G G + G + S + G P Q YP Sbjct: 729 --QGKPGLAGLP--GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 784 Query: 231 LSSPRG-----GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284 L +G G PG G G + + R G G GPS G Sbjct: 785 LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 844 Query: 285 -----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK-GPADMASQCWG 338 G P P P + G+ G+PG + G + G AGK GP Sbjct: 845 EKGKLGVPGLPGYPGRQ----GPKGSTGFPGFPGANGEKGAR-GVAGKPGPRGQRGPTGP 899 Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ-PYGG 397 + A G + G+SGG G P P + G PQ P G Sbjct: 900 RGSRGARGPTGKPGPK----------GTSGGDGPP--------GPPGERGPQGPQGPVGF 941 Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ-----SAMGGLSYTQQIP 452 P +GPP GP G PG P QR QG+ +G T + Sbjct: 942 PGP----KGPP-GPPGKDGLPGHP-----GQRGETGFQGKTGPPGPGGVVGPQGPTGETG 991 Query: 453 PYGQQG----PSGYGQQGQTPYYNQQS----PHPQ----------------QQQPPYSQQ 488 P G++G P G+QG ++ P PQ ++ P +Q Sbjct: 992 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1051 Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS-QQPSQPPHQQSPAPYPSQQSTTQQHPQS 547 P P P P + S+ P +P Q P P + + ++ PQ Sbjct: 1052 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1111 Query: 548 QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDS 607 P + Q P P PA S + Q + PP Q Sbjct: 1112 --PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1169 Query: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667 G+ + GQ+ M D+ G G P + G+ Sbjct: 1170 VGAPGIAGGDGEPGPRGQQGM-------------FGQKGDEGARGFPGPPGP-IGLQGLP 1215 Query: 668 SSQGEQS-NPAQSPFSPHTSPHLPGIRGP-----SPSPVGSPASVAQSRSGPLSPAAVPG 721 GE+ N P P P PG RGP + P G P SV G + PG Sbjct: 1216 GPPGEKGENGDVGPMGP---PGPPGPRGPQGPNGADGPQGPPGSVGSV--GGVGEKGEPG 1270 Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM----QRNPQMPQYSSPQPGSALSPRQPS 777 P PP + A G + P PG P P Sbjct: 1271 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1330 Query: 778 -------GGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGM 828 GQ G + G GP G G+ GP G P P A AG Sbjct: 1331 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG----PPGKRGPPGA----AGA 1382 Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-------S 881 G GA G+ G G PP T P G A +P + +P VG + Sbjct: 1383 EGRQGEKGAKGEA-GAEG-PPGKTGPVGPQGPAG---KPGPEGLRGIPGPVGEQGLPGAA 1437 Query: 882 GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMI 941 G PPG M PPG P + G P +G G+I Sbjct: 1438 GQDGPPGPMG--------------------PPGLPGLK-------GDPGSKGEKGHPGLI 1470 Query: 942 NPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973 GPP G G SP G G + Sbjct: 1471 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1502 Score = 96.7 bits (239), Expect = 2e-19 Identities = 229/972 (23%), Positives = 291/972 (29%), Gaps = 190/972 (19%) Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPG 95 GG ++ A E G+ G + GPP P GK + G G GG G G PG Sbjct: 556 GGPGSSGAKGESGD----PGPQGPRGVQGPPGPTGKPGKRGRP----GADGGRGMPGEPG 607 Query: 96 AE--------PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPA 147 A+ P L G+ G R PPG G DG P A P Sbjct: 608 AKGDRGFDGLPGLPGDKGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 665 Query: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF 207 G P G G PG+A G++ GP+ N G Sbjct: 666 LG---PRGTP----------------GAPGQPGMA--------GVDGPPGPKGNMGPQGE 698 Query: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267 P P P P +G G A G+ PP S Sbjct: 699 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK-- 756 Query: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG--GDYSGGPQDG 323 GA+G GP G P P + + L +G G+PG GD G Sbjct: 757 ----GALGPPGPQGPIG-YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 811 Query: 324 GAGK-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381 G+ GP R P P G +G G P Sbjct: 812 EVGQIGP--------------------------RGEDGPEGPKGRAGPTGDP-------- 837 Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441 P Q G+ G Y +QGP G+PG P A Sbjct: 838 GPSGQAGEKGKLGVPGLPGYPGRQGPKGST----GFPGFP---------------GANGE 878 Query: 442 MGGLSYTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497 G + P GQ+GP+G G +G T P + PP Sbjct: 879 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTG-------KPGPKGTSGGDGPPGPPGERG 931 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557 P Q P P + P PP + +P Q+ T ++ PP Sbjct: 932 PQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPP------- 975 Query: 558 SPYQQQQPQQPAPST--LSQQA--AYPQPQSQQSQQTAYSQQRF---PPPQELSQDSFGS 610 P PQ P T + ++ P P +Q A ++ P PQ +S + Sbjct: 976 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1035 Query: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS-PG-VSTSGIS 667 P G Q L P P GS + GT G + PG G Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1095 Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-------RSGPLSPAA 718 GE+ P + P G++GP P P G S + G Sbjct: 1096 GPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1153 Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS---PRQ 775 G PP PP Q + IA G Q + A P Sbjct: 1154 DKGENGPPGPPGLQGP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1207 Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGIN 833 P G Q G ++ G GP G G GP+G P+ PN P S G GG+ Sbjct: 1208 PIGLQGLPGPPG-EKGENGDVGPMGPPGPPGPRG--PQGPNGADGPQGPPGSVGSVGGVG 1264 Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893 G G+ G PG P + + G GP A PP G PPG K Sbjct: 1265 EKGEPGEA-GNPGPPGEAGVGGPKGERGEKGEA--GPPGAAGPP----GAKGPPGDDGPK 1317 Query: 894 TQETAVAMHVAANSIQNRPPGYPN-MNQGGMMG----TGPPYGQGINSMAGMINPQGPPY 948 V PPG P Q G+ G G P G +G P GPP Sbjct: 1318 GNPGPVGFPGDPG-----PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1372 Query: 949 SMGGTMANNSAG 960 G A + G Sbjct: 1373 KRGPPGAAGAEG 1384 Score = 90.1 bits (222), Expect = 2e-17 Identities = 237/1039 (22%), Positives = 326/1039 (31%), Gaps = 141/1039 (13%) Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAV-GPPQPLGKELQDGAESNGGGGGGGAGSGGGP 94 GG+ + E +A A + A+ GPP P+G + G G G G G G P Sbjct: 512 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG-PVGGPGSSGAKGESGDP 570 Query: 95 GAEPDLKNSNGNAGP--------RPALNNNLTEP--PGGGGGGSSDGV-GAPPHSAAAAL 143 G + + G GP RP + P PG G DG+ G P Sbjct: 571 GPQGP-RGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 629 Query: 144 PPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP-GL-------AALQSGGGGGLEPY 195 P G P + + + G+ P GL A G G++ Sbjct: 630 RGPQ---GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686 Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255 GP+ N G P P P P +G G A G+ PP Sbjct: 687 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746 Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG 313 S GA+G GP G P P + + L +G G+PG Sbjct: 747 PGKEGQSGEK------GALGPPGPQGP-IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799 Query: 314 --------GDYSG----GPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG--------A 353 GD GP+ +GP A + A G Sbjct: 800 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 859 Query: 354 QQRSHHAPMSPGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412 +Q + PG G G+ AR P Q G P+ G + + G P G Sbjct: 860 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-PKGTS 918 Query: 413 QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYY 471 G G PG P G + PQ Q +G P G+ G G+ GQ+G+T + Sbjct: 919 GGDGPPGPP-GERGPQ--------GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 969 Query: 472 NQQSPHPQ-----QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526 + P Q P P + H P Q P P Sbjct: 970 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1029 Query: 527 HQQSPA---------PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577 + PA P Q P SP ++ P L + Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1089 Query: 578 AYPQPQSQQSQQTAYSQQ--RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR 635 P ++ A ++ + P ++ Q G + P+ S G ED + Sbjct: 1090 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA--GSPG--EDGDKGEIGE 1145 Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRG 694 P ++ P G G P V GI+ GE Q F G G Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGP-VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204 Query: 695 PSPSPV------GSPASVAQSRS-GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747 P P P+ G P ++ GP+ P PG PR P G + + P S+ Sbjct: 1205 P-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG----PRGPQGPNGA-DGPQGPPGSVG 1258 Query: 748 QDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807 G ++ +PG A +P P G+ G ++ G GP G GP G Sbjct: 1259 SVGGVGEKG---------EPGEAGNPGPP--GEAGVGGPKGERGEKGEAGPPGAA-GPPG 1306 Query: 808 GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI--------PPYGTLPPGRMS 859 + P + P N G G P G G GQ G+ P PPG Sbjct: 1307 A--KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSG 1363 Query: 860 HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-QNRPPGYPNM 918 A P GP PP +G G K + A + P G P Sbjct: 1364 EAG----PPGPPGKRGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418 Query: 919 NQGGMMGTGPPYG-QGINSMAGMINPQGP--PYSMGGTMAN-NSAGMAASPEMMGLGDVK 974 G+ G P G QG+ AG P GP P + G + S G P ++GL Sbjct: 1419 E--GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---- 1472 Query: 975 LTPATKMNNKAD-GTPKTE 992 + P + K D G P T+ Sbjct: 1473 IGPPGEQGEKGDRGLPGTQ 1491 Score = 80.5 bits (197), Expect = 2e-14 Identities = 229/986 (23%), Positives = 299/986 (30%), Gaps = 188/986 (19%) Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGA-EPDL--KNSNGNAGPR---------- 110 GP P ++ + NG G G G G P EP + + G AGP Sbjct: 414 GPGVPAETDITE-TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQG 472 Query: 111 ---PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAA 167 P + PPG G +DG+ PP + P YG G + SA A A A Sbjct: 473 PTGPPGDPGDRGPPGRPGLPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQA 530 Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQN--SHDHGFPNHQYNSYYPNRSAYPPP 225 + Q + P +G G P GP + + G P Q R PP Sbjct: 531 ILQQARIALRGPPGPMGLTGRPG---PVGGPGSSGAKGESGDPGPQ-----GPRGVQGPP 582 Query: 226 APAYALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--GGPSAA 282 P G PG G A G + P + + F + G G Sbjct: 583 GPT--------GKPGKRGRPGADGGRGMPGEPGAK-------GDRGFDGLPGLPGDKGHR 627 Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342 G PQ P + + G +G PG GP+ +G Q A Sbjct: 628 GERGPQGPPGPPGDDGMRGEDGEIGPRGLPG---EAGPRGLLGPRGTPGAPGQPGMAGVD 684 Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402 + G Q P PG G G P P P+ G+ PQ G Sbjct: 685 GPPGPKGNMGPQGE----PGPPGQQGNPGP--QGLPGPQGPIGPPGEKGPQGKPGLAGLP 738 Query: 403 QQQGPPSGP----QQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ--------- 449 GPP P Q G P G Q P YP + + GL ++ Sbjct: 739 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 798 Query: 450 ----------------QIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQP 489 QI P G+ GP G G G Q + P P Sbjct: 799 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 858 Query: 490 PSQTPHAQPSYQQQPQSQPPQ----LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545 Q P + P + + + P Q+ P A P+ + + Sbjct: 859 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 918 Query: 546 QSQPPYSQPQAQSPYQQQQP-------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598 P P + P Q P P P +P Q +T + + P Sbjct: 919 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP----GQRGETGFQGKTGP 974 Query: 599 PPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658 P G + P G Q P + D P G G Sbjct: 975 PGPGGVVGPQGPTGETGPIGERGHPGPPGPP-GEQGLPGAAGKEGAKGDPGPQGISGKDG 1033 Query: 659 PGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-RSGPLS 715 P +G+ GE+ P +P L G GP P PVGSP + +GP+ Sbjct: 1034 P----AGLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1084 Query: 716 PAAVPGNQMPPRP--------------PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761 PG Q PP P P+G+ D + P + A G + + Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-DGVQGP-VGLPGPAGPAGSPGEDGDKGE 1142 Query: 762 YSSP-QPGS-----ALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-----GQYGPQG--G 808 P Q GS P P G Q G G GP+G GQ G +G G Sbjct: 1143 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD-GEPGPRGQQGMFGQKGDEGARG 1201 Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866 +P P L P G G + PMG G PPG Sbjct: 1202 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG--------------PPGPRG------- 1240 Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926 P GPN A+ PQ G GG+ K + A N PG P G G Sbjct: 1241 PQGPNGAD-GPQGPPGSVGSVGGVGEKGEPGE-----AGN------PGPP-----GEAGV 1283 Query: 927 GPPYGQ-GINSMAGMINPQGPPYSMG 951 G P G+ G AG GPP + G Sbjct: 1284 GGPKGERGEKGEAGPPGAAGPPGAKG 1309 Score = 79.3 bits (194), Expect = 4e-14 Identities = 174/760 (22%), Positives = 235/760 (30%), Gaps = 105/760 (13%) Query: 32 REEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG-----GGGG 86 R E G E A G+ +GQ E +G P G + G + + G G G Sbjct: 819 RGEDGPEGPKGRAGPTGD-PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 877 Query: 87 GAGSGGGPGAEPDLKNSNGNAGPRPALN-NNLTEPPGGGGGGSSDGVGAPPHSAAAALPP 145 G+ G G +P + G GPR + T PG G DG PP P Sbjct: 878 EKGARGVAG-KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 936 Query: 146 PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDH 205 GF P G P H G+ G GG + P GP + Sbjct: 937 GPVGFPGPKG--PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ-GPTGETGPI 993 Query: 206 GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSS 265 G H P P A G SG AG + P + + Sbjct: 994 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1053 Query: 266 FAQQRFGAMGGGGPSAAGG-----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP 320 + G G GP + G GT P P P A G +G PG GP Sbjct: 1054 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1112 Query: 321 QDGGAGKGPADMASQCWGAAAAAA-------AAAAASGGAQQRSHHAPM----------S 363 +GP + A + G + + P + Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1172 Query: 364 PGSSGGGGQPLART----------------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407 PG +GG G+P R P P P+ G P G N GP Sbjct: 1173 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232 Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY----G 463 P P G P P G+ PQ P ++ ++GG+ + G GP G G Sbjct: 1233 PGPP--GPRGPQGPNGADGPQGPPGSV-----GSVGGVGEKGEPGEAGNPGPPGEAGVGG 1285 Query: 464 QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523 +G+ + P P PP ++ PP P+ P + P Sbjct: 1286 PKGERGEKGEAGP-PGAAGPPGAKGPPGD---------DGPKGNPGPVGFPGDP------ 1329 Query: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 PP + PA Q + P QP P + P P AA + + Sbjct: 1330 GPPGEPGPA---GQDGVGGDKGEDGDP-GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1385 Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN-LSLQSRPSSLPDL 642 + + PP G P + K G E + + LP Sbjct: 1386 QGEKGAKGEAGAEGPP---------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436 Query: 643 SGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQ-SPFSPHTSPHLPGIRGPSPSPV 700 +G D P G G PG+ G S+GE+ +P P G RG P Sbjct: 1437 AGQ--DGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-LPGTQ 1491 Query: 701 GSPASVAQSR----SGPLSPAAVPGNQMP-PRPPSGQSDS 735 GSP + +GPL P PG +P P+ P G S Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPG--LPGPQGPKGNKGS 1529 Score = 52.4 bits (124), Expect = 5e-06 Identities = 106/423 (25%), Positives = 139/423 (32%), Gaps = 95/423 (22%) Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPA-------QSPFSP------HTSPHLPGIRG 694 D P G +G + P G G+Q NP Q P P P L G+ G Sbjct: 684 DGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 739 Query: 695 PSPSPVGSPASVAQSRS-------GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747 + P G P QS GP P PG PR G +D + ++ Sbjct: 740 -ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG----PRGVKG-ADGVRGLKGSKGEKG 793 Query: 748 QD-----RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG--SYQQNSMGSYGPQG 800 +D +G M + P P P G TG S Q G G G Sbjct: 794 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853 Query: 801 -----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQMH--GQPG 846 G+ GP+G G+P P N A + G G P G+ G G+PG Sbjct: 854 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 913 Query: 847 IPPYGTLPPGRMSHASMGNRPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVA 904 P GT S G+ P GP P PQ G P P G + + H Sbjct: 914 --PKGT---------SGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHPG 961 Query: 905 ANSI-----QNRPPGYPNMNQGGMMGT-------------------GPPYGQGINSMAGM 940 + PPG GG++G GPP QG+ AG Sbjct: 962 QRGETGFQGKTGPPG-----PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016 Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP-KTESKSKKSS 999 +G P G + + AG+ P GL + P K G P S ++ S Sbjct: 1017 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1076 Query: 1000 SST 1002 + T Sbjct: 1077 AGT 1079 Score = 47.8 bits (112), Expect = 1e-04 Identities = 83/339 (24%), Positives = 111/339 (32%), Gaps = 82/339 (24%) Query: 661 VSTSGISSSQGEQSNPA-----------QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS 709 ++ G +G++ PA P P PG++GP+ P G P Sbjct: 428 INGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPGDPGD---- 482 Query: 710 RSGPLSPAAVPGNQMPPRPPS-------------GQSDSIMHPSMNQSSIAQDRGYMQRN 756 GP +PG P PP + +I +I Q R Sbjct: 483 -RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 541 Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPN 814 P P + +PG P GG +G + G GPQG G GP G + P Sbjct: 542 PPGPMGLTGRPG-------PVGGPGSSGA----KGESGDPGPQGPRGVQGPPGPTGK-PG 589 Query: 815 YNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPNMA 873 P A+ GM G G G G PG+P G H G R P GP Sbjct: 590 KRGRPGAD-GGRGMPGEPGAKGDRG-FDGLPGLP-------GDKGHR--GERGPQGPP-- 636 Query: 874 NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPN-MNQGGMMGT-GPPYG 931 PPG + ++ + P G P G++G G P Sbjct: 637 -----------GPPGDDGMRGEDGEIG-----------PRGLPGEAGPRGLLGPRGTPGA 674 Query: 932 QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 G MAG+ P GP +MG G +P GL Sbjct: 675 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713 Score = 45.8 bits (107), Expect = 5e-04 Identities = 71/258 (27%), Positives = 87/258 (33%), Gaps = 58/258 (22%) Query: 7 PAAASSLGNPPPP----PP----SELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES 58 P + G P PP PP +E ++ E+ + EAG E G A Sbjct: 1359 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418 Query: 59 EGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--PALNNN 116 EG G P P+G++ GA G G G G PG P LK G+ G + P L Sbjct: 1419 EG-LRGIPGPVGEQGLPGA----AGQDGPPGPMGPPGL-PGLKGDPGSKGEKGHPGL-IG 1471 Query: 117 LTEPPGGGGGGSSDGV----GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172 L PPG G G+ G+P +P PA G P Sbjct: 1472 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP------------------- 1512 Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPP-----PAP 227 PGL Q G G + GP D G P P S PP P P Sbjct: 1513 ----GPPGLPGPQ--GPKGNKGSTGPAGQKGDSGLPG-------PPGSPGPPGEVIQPLP 1559 Query: 228 AYALSSPRGGTPGSGAAA 245 + R T G A A Sbjct: 1560 ILSSKKTRRHTEGMQADA 1577 Score = 40.8 bits (94), Expect = 0.015 Identities = 56/201 (27%), Positives = 67/201 (33%), Gaps = 13/201 (6%) Query: 791 NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850 N G+YG +G Q G P L AG AG + P G G G PG P Sbjct: 429 NGHGAYGEKG-----QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPG-DPG 481 Query: 851 GTLPPGRMSHASMGNRPYGPN-MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQ 909 PPGR P P M +P + G P ++ Q A+ A Sbjct: 482 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ--ARIAL 539 Query: 910 NRPPGYPNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMM 968 PPG M G G G P G +G PQGP G G P Sbjct: 540 RGPPG--PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597 Query: 969 GLGDVKLTPATKMNNKADGTP 989 G + P K + DG P Sbjct: 598 GGRGMPGEPGAKGDRGFDGLP 618 Score = 40.8 bits (94), Expect = 0.015 Identities = 106/513 (20%), Positives = 147/513 (28%), Gaps = 79/513 (15%) Query: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186 Q K PP P G + GPQ P + + E G PP P P Q LPG + G Sbjct: 969 QGKTGPPGPGG---VVGPQGPTGETGPIGERGHPGPPGP---PGEQ--GLPG-----AAG 1015 Query: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246 + A D ++ G+ G + + P Sbjct: 1016 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP-------------- 1061 Query: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GPYDRVRTEPGIGPEGNMSTGA 1304 QGP G +G P R + G + + P + P G GP GP+G Sbjct: 1062 ---QGPPGPVGSPGERGSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1117 Query: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP--------------- 1349 Q + P SP + + + + S G++ G P Sbjct: 1118 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK-GENGPPGPPGLQGPVGAPGIA 1176 Query: 1350 --SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP 1407 G P P Q M+ Q+ R G GPP + P G+ PP Sbjct: 1177 GGDGEPGPRGQQGMFGQKGDEGAR---GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233 Query: 1408 AQPQPASQQ----QAAQPSPQQDVYNQYGNAYPATATAATERRP-----AGGPQNQF--- 1455 P P Q P V + G A P GGP+ + Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293 Query: 1456 -----PFQFGRDRVSAPPGTNAQQNMPPQM----MGGPIQASAEVAQQGTMWQGRNDMTY 1506 P G PPG + + P + GP Q G D Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1353 Query: 1507 NYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPP--YGPSAPVPPM 1564 P G + R +G+ G PP GP P P Sbjct: 1354 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1413 Query: 1565 TRPPPSNYQ--PPPSMQNHIPQVSSPAPLPRPM 1595 +P P + P P + +P + P PM Sbjct: 1414 GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1446 Score = 37.7 bits (86), Expect = 0.13 Identities = 127/570 (22%), Positives = 167/570 (29%), Gaps = 115/570 (20%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ-IPPLPGM----------- 1179 PP PAG + GP Q + + GD PP P + +P PG Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 514 Query: 1180 -SRSNSVGIQDAFNDGSDSTFQKRN----------SMTPNPGYQPSMNTSDMMGRMSYEP 1228 S+ ++ Q+A + + Q+ +T PG +S G Sbjct: 515 GSKGPTISAQEA---QAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 571 Query: 1229 NKDPYGSM-RKAPGSDPFMSSGQGPNGGMGDPYSRAAG--------PGLGNVAMGPRQHY 1279 + P G P P G +GG G P A PGL + Sbjct: 572 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 631 Query: 1280 PYGGP----YDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334 P G P D +R E G IGP G P+ G+ P P Q Sbjct: 632 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR----------GLLGPRGTPGAPGQPGMA 681 Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394 D G P G P P Q Q P G GPP ++ Sbjct: 682 GVDGPPGPKGNMG-PQGEPGPPGQ--QGNPGPQGLPGP-QGPIGPPGEKGP--------- 728 Query: 1395 TGQGQPQQQQLPPAQPQPASQQQAAQ---------PSPQQDVYNQYGNAYPATATAATER 1445 QG+P LP A P + Q P PQ + G P A Sbjct: 729 --QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----GYPGPRGVKGADGV 782 Query: 1446 RPAGGPQNQ-----FP-------FQFGRDRVS--APPGTNAQQNMPPQMMGGPIQASAEV 1491 R G + + FP + R V P G + + P+ GP Sbjct: 783 RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG--PKGRAGPTGDPGPS 840 Query: 1492 AQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPS-HGT 1550 Q G + Y RQ + P + G N ++ A P G Sbjct: 841 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN-------GEKGARGVAGKPGPRGQ 893 Query: 1551 RQP--PYGPSAPVPPMTRPPPSNYQ----PPPSMQNHIPQ-VSSPAPLPRPMENRTSPSK 1603 R P P G P +P P PP PQ P P P P K Sbjct: 894 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 953 Query: 1604 SPFL-HSGMKMQ-----KAGPPVPASHIAP 1627 H G + + K GPP P + P Sbjct: 954 DGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983 Score = 37.7 bits (86), Expect = 0.13 Identities = 86/381 (22%), Positives = 121/381 (31%), Gaps = 50/381 (13%) Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV-GIQDAF 1191 P AG GP E G L PP P P G+ ++ V G++ + Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP--IGYPGPRGVKGADGVRGLKGSK 789 Query: 1192 NDGSDSTFQKRNSMTPNPGYQPSMNTS---DMMGRMSYEPNKDPYGSM-RKAPGSDPFMS 1247 + + F PG++ M +G++ P G R P DP S Sbjct: 790 GEKGEDGF---------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 840 Query: 1248 SGQGPNGGMGDP----YSRAAG-------PGLGNVAMGPRQHYPYGGPYDRVRTEPGIGP 1296 G G +G P Y G PG G P R + P GP Sbjct: 841 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP-TGP 899 Query: 1297 EGNMSTGAPQPNLMPS-NPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFP 1355 G S GA P P SG P P ++ Q Q + P G P P Sbjct: 900 RG--SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG-------PKGPPGP 950 Query: 1356 SQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQ 1415 + + Q + G GPP G + TG+ P ++ P P P + Sbjct: 951 PGKDGLPGHPGQRGETGFQGKTGPPG---PGGVVGPQGPTGETGPIGERGHPGPPGPPGE 1007 Query: 1416 QQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQN 1475 Q + ++ P + + PAG FP + G PG + Sbjct: 1008 QGLPGAAGKEGAKGD-----PGPQGISGKDGPAG--LRGFPGERGLPGAQGAPGLKGGEG 1060 Query: 1476 MPPQMMGGPIQASAEVAQQGT 1496 PQ GP+ + E GT Sbjct: 1061 --PQGPPGPVGSPGERGSAGT 1079 Score = 34.3 bits (77), Expect = 1.4 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 14/88 (15%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDL---KPPTPASTPHSQIPPLPGMS----RSNS 1184 PP P G QGP+ + ++ + GD PP P I PLP +S R ++ Sbjct: 1511 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1570 Query: 1185 VGIQ-DA------FNDGSDSTFQKRNSM 1205 G+Q DA ++DG + F NS+ Sbjct: 1571 EGMQADADDNILDYSDGMEEIFGSLNSL 1598 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 102 bits (253), Expect = 6e-21 Identities = 244/1052 (23%), Positives = 312/1052 (29%), Gaps = 206/1052 (19%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERG-----EMKAAAGQESEGP 61 P + PP P K+ G A +RG + G E Sbjct: 521 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 580 Query: 62 AVGPPQPLGKELQDGAESNGGGGG--GGAGSGG--GPGAEPDLKNSNGNAGPRPALNNNL 117 GPP P G + G + G G G AG G GP P G AG + Sbjct: 581 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG--------V 632 Query: 118 TEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173 PPG G G PP + LP P G P + P Sbjct: 633 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP--------------- 677 Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF---PNHQYNSYYPNRSAYPPPAPAYA 230 Q PGLA L G G + G + S + G P Q YP Sbjct: 678 --QGKPGLAGLP--GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 733 Query: 231 LSSPRG-----GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284 L +G G PG G G + + R G G GPS G Sbjct: 734 LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 793 Query: 285 -----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK-GPADMASQCWG 338 G P P P + G+ G+PG + G + G AGK GP Sbjct: 794 EKGKLGVPGLPGYPGRQ----GPKGSTGFPGFPGANGEKGAR-GVAGKPGPRGQRGPTGP 848 Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ-PYGG 397 + A G + G+SGG G P P + G PQ P G Sbjct: 849 RGSRGARGPTGKPGPK----------GTSGGDGPP--------GPPGERGPQGPQGPVGF 890 Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ-----SAMGGLSYTQQIP 452 P +GPP GP G PG P QR QG+ +G T + Sbjct: 891 PGP----KGPP-GPPGKDGLPGHP-----GQRGETGFQGKTGPPGPGGVVGPQGPTGETG 940 Query: 453 PYGQQG----PSGYGQQGQTPYYNQQS----PHPQ----------------QQQPPYSQQ 488 P G++G P G+QG ++ P PQ ++ P +Q Sbjct: 941 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1000 Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS-QQPSQPPHQQSPAPYPSQQSTTQQHPQS 547 P P P P + S+ P +P Q P P + + ++ PQ Sbjct: 1001 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1060 Query: 548 QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDS 607 P + Q P P PA S + Q + PP Q Sbjct: 1061 --PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1118 Query: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667 G+ + GQ+ M D+ G G P + G+ Sbjct: 1119 VGAPGIAGGDGEPGPRGQQGM-------------FGQKGDEGARGFPGPPGP-IGLQGLP 1164 Query: 668 SSQGEQS-NPAQSPFSPHTSPHLPGIRGP-----SPSPVGSPASVAQSRSGPLSPAAVPG 721 GE+ N P P P PG RGP + P G P SV G + PG Sbjct: 1165 GPPGEKGENGDVGPMGP---PGPPGPRGPQGPNGADGPQGPPGSVGSV--GGVGEKGEPG 1219 Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM----QRNPQMPQYSSPQPGSALSPRQPS 777 P PP + A G + P PG P P Sbjct: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1279 Query: 778 -------GGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGM 828 GQ G + G GP G G+ GP G P P A AG Sbjct: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG----PPGKRGPPGA----AGA 1331 Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-------S 881 G GA G+ G G PP T P G A +P + +P VG + Sbjct: 1332 EGRQGEKGAKGEA-GAEG-PPGKTGPVGPQGPAG---KPGPEGLRGIPGPVGEQGLPGAA 1386 Query: 882 GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMI 941 G PPG M PPG P + G P +G G+I Sbjct: 1387 GQDGPPGPMG--------------------PPGLPGLK-------GDPGSKGEKGHPGLI 1419 Query: 942 NPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973 GPP G G SP G G + Sbjct: 1420 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1451 Score = 96.7 bits (239), Expect = 2e-19 Identities = 229/972 (23%), Positives = 291/972 (29%), Gaps = 190/972 (19%) Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPG 95 GG ++ A E G+ G + GPP P GK + G G GG G G PG Sbjct: 505 GGPGSSGAKGESGD----PGPQGPRGVQGPPGPTGKPGKRGRP----GADGGRGMPGEPG 556 Query: 96 AE--------PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPA 147 A+ P L G+ G R PPG G DG P A P Sbjct: 557 AKGDRGFDGLPGLPGDKGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 614 Query: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF 207 G P G G PG+A G++ GP+ N G Sbjct: 615 LG---PRGTP----------------GAPGQPGMA--------GVDGPPGPKGNMGPQGE 647 Query: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267 P P P P +G G A G+ PP S Sbjct: 648 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK-- 705 Query: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG--GDYSGGPQDG 323 GA+G GP G P P + + L +G G+PG GD G Sbjct: 706 ----GALGPPGPQGPIG-YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 760 Query: 324 GAGK-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381 G+ GP R P P G +G G P Sbjct: 761 EVGQIGP--------------------------RGEDGPEGPKGRAGPTGDP-------- 786 Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441 P Q G+ G Y +QGP G+PG P A Sbjct: 787 GPSGQAGEKGKLGVPGLPGYPGRQGPKGST----GFPGFP---------------GANGE 827 Query: 442 MGGLSYTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497 G + P GQ+GP+G G +G T P + PP Sbjct: 828 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTG-------KPGPKGTSGGDGPPGPPGERG 880 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557 P Q P P + P PP + +P Q+ T ++ PP Sbjct: 881 PQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPP------- 924 Query: 558 SPYQQQQPQQPAPST--LSQQA--AYPQPQSQQSQQTAYSQQRF---PPPQELSQDSFGS 610 P PQ P T + ++ P P +Q A ++ P PQ +S + Sbjct: 925 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 984 Query: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS-PG-VSTSGIS 667 P G Q L P P GS + GT G + PG G Sbjct: 985 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044 Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-------RSGPLSPAA 718 GE+ P + P G++GP P P G S + G Sbjct: 1045 GPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102 Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS---PRQ 775 G PP PP Q + IA G Q + A P Sbjct: 1103 DKGENGPPGPPGLQGP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156 Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGIN 833 P G Q G ++ G GP G G GP+G P+ PN P S G GG+ Sbjct: 1157 PIGLQGLPGPPG-EKGENGDVGPMGPPGPPGPRG--PQGPNGADGPQGPPGSVGSVGGVG 1213 Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893 G G+ G PG P + + G GP A PP G PPG K Sbjct: 1214 EKGEPGEA-GNPGPPGEAGVGGPKGERGEKGEA--GPPGAAGPP----GAKGPPGDDGPK 1266 Query: 894 TQETAVAMHVAANSIQNRPPGYPN-MNQGGMMG----TGPPYGQGINSMAGMINPQGPPY 948 V PPG P Q G+ G G P G +G P GPP Sbjct: 1267 GNPGPVGFPGDPG-----PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1321 Query: 949 SMGGTMANNSAG 960 G A + G Sbjct: 1322 KRGPPGAAGAEG 1333 Score = 90.1 bits (222), Expect = 2e-17 Identities = 237/1039 (22%), Positives = 326/1039 (31%), Gaps = 141/1039 (13%) Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAV-GPPQPLGKELQDGAESNGGGGGGGAGSGGGP 94 GG+ + E +A A + A+ GPP P+G + G G G G G G P Sbjct: 461 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG-PVGGPGSSGAKGESGDP 519 Query: 95 GAEPDLKNSNGNAGP--------RPALNNNLTEP--PGGGGGGSSDGV-GAPPHSAAAAL 143 G + + G GP RP + P PG G DG+ G P Sbjct: 520 GPQGP-RGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 578 Query: 144 PPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP-GL-------AALQSGGGGGLEPY 195 P G P + + + G+ P GL A G G++ Sbjct: 579 RGPQ---GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635 Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255 GP+ N G P P P P +G G A G+ PP Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695 Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG 313 S GA+G GP G P P + + L +G G+PG Sbjct: 696 PGKEGQSGEK------GALGPPGPQGP-IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 748 Query: 314 --------GDYSG----GPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG--------A 353 GD GP+ +GP A + A G Sbjct: 749 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 808 Query: 354 QQRSHHAPMSPGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412 +Q + PG G G+ AR P Q G P+ G + + G P G Sbjct: 809 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-PKGTS 867 Query: 413 QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYY 471 G G PG P G + PQ Q +G P G+ G G+ GQ+G+T + Sbjct: 868 GGDGPPGPP-GERGPQ--------GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 918 Query: 472 NQQSPHPQ-----QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526 + P Q P P + H P Q P P Sbjct: 919 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 978 Query: 527 HQQSPA---------PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577 + PA P Q P SP ++ P L + Sbjct: 979 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1038 Query: 578 AYPQPQSQQSQQTAYSQQ--RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR 635 P ++ A ++ + P ++ Q G + P+ S G ED + Sbjct: 1039 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA--GSPG--EDGDKGEIGE 1094 Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRG 694 P ++ P G G P V GI+ GE Q F G G Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGP-VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153 Query: 695 PSPSPV------GSPASVAQSRS-GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747 P P P+ G P ++ GP+ P PG PR P G + + P S+ Sbjct: 1154 P-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG----PRGPQGPNGA-DGPQGPPGSVG 1207 Query: 748 QDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807 G ++ +PG A +P P G+ G ++ G GP G GP G Sbjct: 1208 SVGGVGEKG---------EPGEAGNPGPP--GEAGVGGPKGERGEKGEAGPPGAA-GPPG 1255 Query: 808 GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI--------PPYGTLPPGRMS 859 + P + P N G G P G G GQ G+ P PPG Sbjct: 1256 A--KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSG 1312 Query: 860 HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-QNRPPGYPNM 918 A P GP PP +G G K + A + P G P Sbjct: 1313 EAG----PPGPPGKRGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367 Query: 919 NQGGMMGTGPPYG-QGINSMAGMINPQGP--PYSMGGTMAN-NSAGMAASPEMMGLGDVK 974 G+ G P G QG+ AG P GP P + G + S G P ++GL Sbjct: 1368 E--GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---- 1421 Query: 975 LTPATKMNNKAD-GTPKTE 992 + P + K D G P T+ Sbjct: 1422 IGPPGEQGEKGDRGLPGTQ 1440 Score = 80.5 bits (197), Expect = 2e-14 Identities = 229/986 (23%), Positives = 299/986 (30%), Gaps = 188/986 (19%) Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGA-EPDL--KNSNGNAGPR---------- 110 GP P ++ + NG G G G G P EP + + G AGP Sbjct: 363 GPGVPAETDITE-TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQG 421 Query: 111 ---PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAA 167 P + PPG G +DG+ PP + P YG G + SA A A A Sbjct: 422 PTGPPGDPGDRGPPGRPGLPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQA 479 Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQN--SHDHGFPNHQYNSYYPNRSAYPPP 225 + Q + P +G G P GP + + G P Q R PP Sbjct: 480 ILQQARIALRGPPGPMGLTGRPG---PVGGPGSSGAKGESGDPGPQ-----GPRGVQGPP 531 Query: 226 APAYALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--GGPSAA 282 P G PG G A G + P + + F + G G Sbjct: 532 GPT--------GKPGKRGRPGADGGRGMPGEPGAK-------GDRGFDGLPGLPGDKGHR 576 Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342 G PQ P + + G +G PG GP+ +G Q A Sbjct: 577 GERGPQGPPGPPGDDGMRGEDGEIGPRGLPG---EAGPRGLLGPRGTPGAPGQPGMAGVD 633 Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402 + G Q P PG G G P P P+ G+ PQ G Sbjct: 634 GPPGPKGNMGPQGE----PGPPGQQGNPGP--QGLPGPQGPIGPPGEKGPQGKPGLAGLP 687 Query: 403 QQQGPPSGP----QQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ--------- 449 GPP P Q G P G Q P YP + + GL ++ Sbjct: 688 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 747 Query: 450 ----------------QIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQP 489 QI P G+ GP G G G Q + P P Sbjct: 748 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 807 Query: 490 PSQTPHAQPSYQQQPQSQPPQ----LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545 Q P + P + + + P Q+ P A P+ + + Sbjct: 808 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867 Query: 546 QSQPPYSQPQAQSPYQQQQP-------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598 P P + P Q P P P +P Q +T + + P Sbjct: 868 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP----GQRGETGFQGKTGP 923 Query: 599 PPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658 P G + P G Q P + D P G G Sbjct: 924 PGPGGVVGPQGPTGETGPIGERGHPGPPGPP-GEQGLPGAAGKEGAKGDPGPQGISGKDG 982 Query: 659 PGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-RSGPLS 715 P +G+ GE+ P +P L G GP P PVGSP + +GP+ Sbjct: 983 P----AGLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1033 Query: 716 PAAVPGNQMPPRP--------------PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761 PG Q PP P P+G+ D + P + A G + + Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-DGVQGP-VGLPGPAGPAGSPGEDGDKGE 1091 Query: 762 YSSP-QPGS-----ALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-----GQYGPQG--G 808 P Q GS P P G Q G G GP+G GQ G +G G Sbjct: 1092 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD-GEPGPRGQQGMFGQKGDEGARG 1150 Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866 +P P L P G G + PMG G PPG Sbjct: 1151 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG--------------PPGPRG------- 1189 Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926 P GPN A+ PQ G GG+ K + A N PG P G G Sbjct: 1190 PQGPNGAD-GPQGPPGSVGSVGGVGEKGEPGE-----AGN------PGPP-----GEAGV 1232 Query: 927 GPPYGQ-GINSMAGMINPQGPPYSMG 951 G P G+ G AG GPP + G Sbjct: 1233 GGPKGERGEKGEAGPPGAAGPPGAKG 1258 Score = 79.3 bits (194), Expect = 4e-14 Identities = 174/760 (22%), Positives = 235/760 (30%), Gaps = 105/760 (13%) Query: 32 REEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG-----GGGG 86 R E G E A G+ +GQ E +G P G + G + + G G G Sbjct: 768 RGEDGPEGPKGRAGPTGD-PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826 Query: 87 GAGSGGGPGAEPDLKNSNGNAGPRPALN-NNLTEPPGGGGGGSSDGVGAPPHSAAAALPP 145 G+ G G +P + G GPR + T PG G DG PP P Sbjct: 827 EKGARGVAG-KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 885 Query: 146 PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDH 205 GF P G P H G+ G GG + P GP + Sbjct: 886 GPVGFPGPKG--PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ-GPTGETGPI 942 Query: 206 GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSS 265 G H P P A G SG AG + P + + Sbjct: 943 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002 Query: 266 FAQQRFGAMGGGGPSAAGG-----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP 320 + G G GP + G GT P P P A G +G PG GP Sbjct: 1003 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1061 Query: 321 QDGGAGKGPADMASQCWGAAAAAA-------AAAAASGGAQQRSHHAPM----------S 363 +GP + A + G + + P + Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121 Query: 364 PGSSGGGGQPLART----------------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407 PG +GG G+P R P P P+ G P G N GP Sbjct: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181 Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY----G 463 P P G P P G+ PQ P ++ ++GG+ + G GP G G Sbjct: 1182 PGPP--GPRGPQGPNGADGPQGPPGSV-----GSVGGVGEKGEPGEAGNPGPPGEAGVGG 1234 Query: 464 QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523 +G+ + P P PP ++ PP P+ P + P Sbjct: 1235 PKGERGEKGEAGP-PGAAGPPGAKGPPGD---------DGPKGNPGPVGFPGDP------ 1278 Query: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 PP + PA Q + P QP P + P P AA + + Sbjct: 1279 GPPGEPGPA---GQDGVGGDKGEDGDP-GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1334 Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN-LSLQSRPSSLPDL 642 + + PP G P + K G E + + LP Sbjct: 1335 QGEKGAKGEAGAEGPP---------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385 Query: 643 SGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQ-SPFSPHTSPHLPGIRGPSPSPV 700 +G D P G G PG+ G S+GE+ +P P G RG P Sbjct: 1386 AGQ--DGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-LPGTQ 1440 Query: 701 GSPASVAQSR----SGPLSPAAVPGNQMP-PRPPSGQSDS 735 GSP + +GPL P PG +P P+ P G S Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPG--LPGPQGPKGNKGS 1478 Score = 52.4 bits (124), Expect = 5e-06 Identities = 106/423 (25%), Positives = 139/423 (32%), Gaps = 95/423 (22%) Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPA-------QSPFSP------HTSPHLPGIRG 694 D P G +G + P G G+Q NP Q P P P L G+ G Sbjct: 633 DGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 688 Query: 695 PSPSPVGSPASVAQSRS-------GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747 + P G P QS GP P PG PR G +D + ++ Sbjct: 689 -ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG----PRGVKG-ADGVRGLKGSKGEKG 742 Query: 748 QD-----RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG--SYQQNSMGSYGPQG 800 +D +G M + P P P G TG S Q G G G Sbjct: 743 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802 Query: 801 -----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQMH--GQPG 846 G+ GP+G G+P P N A + G G P G+ G G+PG Sbjct: 803 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 862 Query: 847 IPPYGTLPPGRMSHASMGNRPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVA 904 P GT S G+ P GP P PQ G P P G + + H Sbjct: 863 --PKGT---------SGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHPG 910 Query: 905 ANSI-----QNRPPGYPNMNQGGMMGT-------------------GPPYGQGINSMAGM 940 + PPG GG++G GPP QG+ AG Sbjct: 911 QRGETGFQGKTGPPG-----PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965 Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP-KTESKSKKSS 999 +G P G + + AG+ P GL + P K G P S ++ S Sbjct: 966 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1025 Query: 1000 SST 1002 + T Sbjct: 1026 AGT 1028 Score = 47.8 bits (112), Expect = 1e-04 Identities = 83/339 (24%), Positives = 111/339 (32%), Gaps = 82/339 (24%) Query: 661 VSTSGISSSQGEQSNPA-----------QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS 709 ++ G +G++ PA P P PG++GP+ P G P Sbjct: 377 INGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPGDPGD---- 431 Query: 710 RSGPLSPAAVPGNQMPPRPPS-------------GQSDSIMHPSMNQSSIAQDRGYMQRN 756 GP +PG P PP + +I +I Q R Sbjct: 432 -RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 490 Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPN 814 P P + +PG P GG +G + G GPQG G GP G + P Sbjct: 491 PPGPMGLTGRPG-------PVGGPGSSGA----KGESGDPGPQGPRGVQGPPGPTGK-PG 538 Query: 815 YNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPNMA 873 P A+ GM G G G G PG+P G H G R P GP Sbjct: 539 KRGRPGAD-GGRGMPGEPGAKGDRG-FDGLPGLP-------GDKGHR--GERGPQGPP-- 585 Query: 874 NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPN-MNQGGMMGT-GPPYG 931 PPG + ++ + P G P G++G G P Sbjct: 586 -----------GPPGDDGMRGEDGEIG-----------PRGLPGEAGPRGLLGPRGTPGA 623 Query: 932 QGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 G MAG+ P GP +MG G +P GL Sbjct: 624 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662 Score = 45.8 bits (107), Expect = 5e-04 Identities = 71/258 (27%), Positives = 87/258 (33%), Gaps = 58/258 (22%) Query: 7 PAAASSLGNPPPP----PP----SELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES 58 P + G P PP PP +E ++ E+ + EAG E G A Sbjct: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367 Query: 59 EGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--PALNNN 116 EG G P P+G++ GA G G G G PG P LK G+ G + P L Sbjct: 1368 EG-LRGIPGPVGEQGLPGA----AGQDGPPGPMGPPGL-PGLKGDPGSKGEKGHPGL-IG 1420 Query: 117 LTEPPGGGGGGSSDGV----GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172 L PPG G G+ G+P +P PA G P Sbjct: 1421 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP------------------- 1461 Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPP-----PAP 227 PGL Q G G + GP D G P P S PP P P Sbjct: 1462 ----GPPGLPGPQ--GPKGNKGSTGPAGQKGDSGLPG-------PPGSPGPPGEVIQPLP 1508 Query: 228 AYALSSPRGGTPGSGAAA 245 + R T G A A Sbjct: 1509 ILSSKKTRRHTEGMQADA 1526 Score = 40.8 bits (94), Expect = 0.015 Identities = 56/201 (27%), Positives = 67/201 (33%), Gaps = 13/201 (6%) Query: 791 NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850 N G+YG +G Q G P L AG AG + P G G G PG P Sbjct: 378 NGHGAYGEKG-----QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPG-DPG 430 Query: 851 GTLPPGRMSHASMGNRPYGPN-MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQ 909 PPGR P P M +P + G P ++ Q A+ A Sbjct: 431 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ--ARIAL 488 Query: 910 NRPPGYPNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMM 968 PPG M G G G P G +G PQGP G G P Sbjct: 489 RGPPG--PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546 Query: 969 GLGDVKLTPATKMNNKADGTP 989 G + P K + DG P Sbjct: 547 GGRGMPGEPGAKGDRGFDGLP 567 Score = 40.8 bits (94), Expect = 0.015 Identities = 106/513 (20%), Positives = 147/513 (28%), Gaps = 79/513 (15%) Query: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186 Q K PP P G + GPQ P + + E G PP P P Q LPG + G Sbjct: 918 QGKTGPPGPGG---VVGPQGPTGETGPIGERGHPGPPGP---PGEQ--GLPG-----AAG 964 Query: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246 + A D ++ G+ G + + P Sbjct: 965 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP-------------- 1010 Query: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GPYDRVRTEPGIGPEGNMSTGA 1304 QGP G +G P R + G + + P + P G GP GP+G Sbjct: 1011 ---QGPPGPVGSPGERGSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1066 Query: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP--------------- 1349 Q + P SP + + + + S G++ G P Sbjct: 1067 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK-GENGPPGPPGLQGPVGAPGIA 1125 Query: 1350 --SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP 1407 G P P Q M+ Q+ R G GPP + P G+ PP Sbjct: 1126 GGDGEPGPRGQQGMFGQKGDEGAR---GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182 Query: 1408 AQPQPASQQ----QAAQPSPQQDVYNQYGNAYPATATAATERRP-----AGGPQNQF--- 1455 P P Q P V + G A P GGP+ + Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242 Query: 1456 -----PFQFGRDRVSAPPGTNAQQNMPPQM----MGGPIQASAEVAQQGTMWQGRNDMTY 1506 P G PPG + + P + GP Q G D Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1302 Query: 1507 NYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPP--YGPSAPVPPM 1564 P G + R +G+ G PP GP P P Sbjct: 1303 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1362 Query: 1565 TRPPPSNYQ--PPPSMQNHIPQVSSPAPLPRPM 1595 +P P + P P + +P + P PM Sbjct: 1363 GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1395 Score = 37.7 bits (86), Expect = 0.13 Identities = 127/570 (22%), Positives = 167/570 (29%), Gaps = 115/570 (20%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ-IPPLPGM----------- 1179 PP PAG + GP Q + + GD PP P + +P PG Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 463 Query: 1180 -SRSNSVGIQDAFNDGSDSTFQKRN----------SMTPNPGYQPSMNTSDMMGRMSYEP 1228 S+ ++ Q+A + + Q+ +T PG +S G Sbjct: 464 GSKGPTISAQEA---QAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 520 Query: 1229 NKDPYGSM-RKAPGSDPFMSSGQGPNGGMGDPYSRAAG--------PGLGNVAMGPRQHY 1279 + P G P P G +GG G P A PGL + Sbjct: 521 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 580 Query: 1280 PYGGP----YDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334 P G P D +R E G IGP G P+ G+ P P Q Sbjct: 581 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR----------GLLGPRGTPGAPGQPGMA 630 Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394 D G P G P P Q Q P G GPP ++ Sbjct: 631 GVDGPPGPKGNMG-PQGEPGPPGQ--QGNPGPQGLPGP-QGPIGPPGEKGP--------- 677 Query: 1395 TGQGQPQQQQLPPAQPQPASQQQAAQ---------PSPQQDVYNQYGNAYPATATAATER 1445 QG+P LP A P + Q P PQ + G P A Sbjct: 678 --QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----GYPGPRGVKGADGV 731 Query: 1446 RPAGGPQNQ-----FP-------FQFGRDRVS--APPGTNAQQNMPPQMMGGPIQASAEV 1491 R G + + FP + R V P G + + P+ GP Sbjct: 732 RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG--PKGRAGPTGDPGPS 789 Query: 1492 AQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPS-HGT 1550 Q G + Y RQ + P + G N ++ A P G Sbjct: 790 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN-------GEKGARGVAGKPGPRGQ 842 Query: 1551 RQP--PYGPSAPVPPMTRPPPSNYQ----PPPSMQNHIPQ-VSSPAPLPRPMENRTSPSK 1603 R P P G P +P P PP PQ P P P P K Sbjct: 843 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 902 Query: 1604 SPFL-HSGMKMQ-----KAGPPVPASHIAP 1627 H G + + K GPP P + P Sbjct: 903 DGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932 Score = 37.7 bits (86), Expect = 0.13 Identities = 86/381 (22%), Positives = 121/381 (31%), Gaps = 50/381 (13%) Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV-GIQDAF 1191 P AG GP E G L PP P P G+ ++ V G++ + Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP--IGYPGPRGVKGADGVRGLKGSK 738 Query: 1192 NDGSDSTFQKRNSMTPNPGYQPSMNTS---DMMGRMSYEPNKDPYGSM-RKAPGSDPFMS 1247 + + F PG++ M +G++ P G R P DP S Sbjct: 739 GEKGEDGF---------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 789 Query: 1248 SGQGPNGGMGDP----YSRAAG-------PGLGNVAMGPRQHYPYGGPYDRVRTEPGIGP 1296 G G +G P Y G PG G P R + P GP Sbjct: 790 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP-TGP 848 Query: 1297 EGNMSTGAPQPNLMPS-NPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFP 1355 G S GA P P SG P P ++ Q Q + P G P P Sbjct: 849 RG--SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG-------PKGPPGP 899 Query: 1356 SQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQ 1415 + + Q + G GPP G + TG+ P ++ P P P + Sbjct: 900 PGKDGLPGHPGQRGETGFQGKTGPPG---PGGVVGPQGPTGETGPIGERGHPGPPGPPGE 956 Query: 1416 QQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQN 1475 Q + ++ P + + PAG FP + G PG + Sbjct: 957 QGLPGAAGKEGAKGD-----PGPQGISGKDGPAG--LRGFPGERGLPGAQGAPGLKGGEG 1009 Query: 1476 MPPQMMGGPIQASAEVAQQGT 1496 PQ GP+ + E GT Sbjct: 1010 --PQGPPGPVGSPGERGSAGT 1028 Score = 34.3 bits (77), Expect = 1.4 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 14/88 (15%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDL---KPPTPASTPHSQIPPLPGMS----RSNS 1184 PP P G QGP+ + ++ + GD PP P I PLP +S R ++ Sbjct: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1519 Query: 1185 VGIQ-DA------FNDGSDSTFQKRNSM 1205 G+Q DA ++DG + F NS+ Sbjct: 1520 EGMQADADDNILDYSDGMEEIFGSLNSL 1547 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 102 bits (253), Expect = 6e-21 Identities = 244/1052 (23%), Positives = 312/1052 (29%), Gaps = 206/1052 (19%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERG-----EMKAAAGQESEGP 61 P + PP P K+ G A +RG + G E Sbjct: 560 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 619 Query: 62 AVGPPQPLGKELQDGAESNGGGGG--GGAGSGG--GPGAEPDLKNSNGNAGPRPALNNNL 117 GPP P G + G + G G G AG G GP P G AG + Sbjct: 620 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG--------V 671 Query: 118 TEPPGGGGGGSSDGVGAPP----HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173 PPG G G PP + LP P G P + P Sbjct: 672 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP--------------- 716 Query: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF---PNHQYNSYYPNRSAYPPPAPAYA 230 Q PGLA L G G + G + S + G P Q YP Sbjct: 717 --QGKPGLAGLP--GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 772 Query: 231 LSSPRG-----GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284 L +G G PG G G + + R G G GPS G Sbjct: 773 LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 832 Query: 285 -----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGK-GPADMASQCWG 338 G P P P + G+ G+PG + G + G AGK GP Sbjct: 833 EKGKLGVPGLPGYPGRQ----GPKGSTGFPGFPGANGEKGAR-GVAGKPGPRGQRGPTGP 887 Query: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ-PYGG 397 + A G + G+SGG G P P + G PQ P G Sbjct: 888 RGSRGARGPTGKPGPK----------GTSGGDGPP--------GPPGERGPQGPQGPVGF 929 Query: 398 TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQ-----SAMGGLSYTQQIP 452 P +GPP GP G PG P QR QG+ +G T + Sbjct: 930 PGP----KGPP-GPPGKDGLPGHP-----GQRGETGFQGKTGPPGPGGVVGPQGPTGETG 979 Query: 453 PYGQQG----PSGYGQQGQTPYYNQQS----PHPQ----------------QQQPPYSQQ 488 P G++G P G+QG ++ P PQ ++ P +Q Sbjct: 980 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1039 Query: 489 PPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS-QQPSQPPHQQSPAPYPSQQSTTQQHPQS 547 P P P P + S+ P +P Q P P + + ++ PQ Sbjct: 1040 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1099 Query: 548 QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDS 607 P + Q P P PA S + Q + PP Q Sbjct: 1100 --PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1157 Query: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667 G+ + GQ+ M D+ G G P + G+ Sbjct: 1158 VGAPGIAGGDGEPGPRGQQGM-------------FGQKGDEGARGFPGPPGP-IGLQGLP 1203 Query: 668 SSQGEQS-NPAQSPFSPHTSPHLPGIRGP-----SPSPVGSPASVAQSRSGPLSPAAVPG 721 GE+ N P P P PG RGP + P G P SV G + PG Sbjct: 1204 GPPGEKGENGDVGPMGP---PGPPGPRGPQGPNGADGPQGPPGSVGSV--GGVGEKGEPG 1258 Query: 722 NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM----QRNPQMPQYSSPQPGSALSPRQPS 777 P PP + A G + P PG P P Sbjct: 1259 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1318 Query: 778 -------GGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGM 828 GQ G + G GP G G+ GP G P P A AG Sbjct: 1319 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG----PPGKRGPPGA----AGA 1370 Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-------S 881 G GA G+ G G PP T P G A +P + +P VG + Sbjct: 1371 EGRQGEKGAKGEA-GAEG-PPGKTGPVGPQGPAG---KPGPEGLRGIPGPVGEQGLPGAA 1425 Query: 882 GMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMI 941 G PPG M PPG P + G P +G G+I Sbjct: 1426 GQDGPPGPMG--------------------PPGLPGLK-------GDPGSKGEKGHPGLI 1458 Query: 942 NPQGPPYSMGGTMANNSAGMAASPEMMGLGDV 973 GPP G G SP G G + Sbjct: 1459 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1490 Score = 96.7 bits (239), Expect = 2e-19 Identities = 229/972 (23%), Positives = 291/972 (29%), Gaps = 190/972 (19%) Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPG 95 GG ++ A E G+ G + GPP P GK + G G GG G G PG Sbjct: 544 GGPGSSGAKGESGD----PGPQGPRGVQGPPGPTGKPGKRGRP----GADGGRGMPGEPG 595 Query: 96 AE--------PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPA 147 A+ P L G+ G R PPG G DG P A P Sbjct: 596 AKGDRGFDGLPGLPGDKGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 653 Query: 148 YGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGF 207 G P G G PG+A G++ GP+ N G Sbjct: 654 LG---PRGTP----------------GAPGQPGMA--------GVDGPPGPKGNMGPQGE 686 Query: 208 PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFA 267 P P P P +G G A G+ PP S Sbjct: 687 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK-- 744 Query: 268 QQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG--GDYSGGPQDG 323 GA+G GP G P P + + L +G G+PG GD G Sbjct: 745 ----GALGPPGPQGPIG-YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 799 Query: 324 GAGK-GPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP-GSSGGGGQPLARTPQPS 381 G+ GP R P P G +G G P Sbjct: 800 EVGQIGP--------------------------RGEDGPEGPKGRAGPTGDP-------- 825 Query: 382 SPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSA 441 P Q G+ G Y +QGP G+PG P A Sbjct: 826 GPSGQAGEKGKLGVPGLPGYPGRQGPKGST----GFPGFP---------------GANGE 866 Query: 442 MGGLSYTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497 G + P GQ+GP+G G +G T P + PP Sbjct: 867 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTG-------KPGPKGTSGGDGPPGPPGERG 919 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557 P Q P P + P PP + +P Q+ T ++ PP Sbjct: 920 PQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPP------- 963 Query: 558 SPYQQQQPQQPAPST--LSQQA--AYPQPQSQQSQQTAYSQQRF---PPPQELSQDSFGS 610 P PQ P T + ++ P P +Q A ++ P PQ +S + Sbjct: 964 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1023 Query: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS-PG-VSTSGIS 667 P G Q L P P GS + GT G + PG G Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083 Query: 668 SSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-------RSGPLSPAA 718 GE+ P + P G++GP P P G S + G Sbjct: 1084 GPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141 Query: 719 VPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALS---PRQ 775 G PP PP Q + IA G Q + A P Sbjct: 1142 DKGENGPPGPPGLQGP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195 Query: 776 PSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGIN 833 P G Q G ++ G GP G G GP+G P+ PN P S G GG+ Sbjct: 1196 PIGLQGLPGPPG-EKGENGDVGPMGPPGPPGPRG--PQGPNGADGPQGPPGSVGSVGGVG 1252 Query: 834 PMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRK 893 G G+ G PG P + + G GP A PP G PPG K Sbjct: 1253 EKGEPGEA-GNPGPPGEAGVGGPKGERGEKGEA--GPPGAAGPP----GAKGPPGDDGPK 1305 Query: 894 TQETAVAMHVAANSIQNRPPGYPN-MNQGGMMG----TGPPYGQGINSMAGMINPQGPPY 948 V PPG P Q G+ G G P G +G P GPP Sbjct: 1306 GNPGPVGFPGDPG-----PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1360 Query: 949 SMGGTMANNSAG 960 G A + G Sbjct: 1361 KRGPPGAAGAEG 1372 Score = 90.1 bits (222), Expect = 2e-17 Identities = 237/1039 (22%), Positives = 326/1039 (31%), Gaps = 141/1039 (13%) Query: 36 GGEAAAAAAAERGEMKAAAGQESEGPAV-GPPQPLGKELQDGAESNGGGGGGGAGSGGGP 94 GG+ + E +A A + A+ GPP P+G + G G G G G G P Sbjct: 500 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG-PVGGPGSSGAKGESGDP 558 Query: 95 GAEPDLKNSNGNAGP--------RPALNNNLTEP--PGGGGGGSSDGV-GAPPHSAAAAL 143 G + + G GP RP + P PG G DG+ G P Sbjct: 559 GPQGP-RGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 617 Query: 144 PPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP-GL-------AALQSGGGGGLEPY 195 P G P + + + G+ P GL A G G++ Sbjct: 618 RGPQ---GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674 Query: 196 AGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSS 255 GP+ N G P P P P +G G A G+ PP Sbjct: 675 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734 Query: 256 SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL--LTSPSSARGYQGYPG 313 S GA+G GP G P P + + L +G G+PG Sbjct: 735 PGKEGQSGEK------GALGPPGPQGP-IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787 Query: 314 --------GDYSG----GPQDGGAGKGPADMASQCWGAAAAAAAAAAASGG--------A 353 GD GP+ +GP A + A G Sbjct: 788 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 847 Query: 354 QQRSHHAPMSPGSSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ 412 +Q + PG G G+ AR P Q G P+ G + + G P G Sbjct: 848 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG-PKGTS 906 Query: 413 QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYY 471 G G PG P G + PQ Q +G P G+ G G+ GQ+G+T + Sbjct: 907 GGDGPPGPP-GERGPQ--------GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957 Query: 472 NQQSPHPQ-----QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPP 526 + P Q P P + H P Q P P Sbjct: 958 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017 Query: 527 HQQSPA---------PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577 + PA P Q P SP ++ P L + Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077 Query: 578 AYPQPQSQQSQQTAYSQQ--RFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR 635 P ++ A ++ + P ++ Q G + P+ S G ED + Sbjct: 1078 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA--GSPG--EDGDKGEIGE 1133 Query: 636 PSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQS-NPAQSPFSPHTSPHLPGIRG 694 P ++ P G G P V GI+ GE Q F G G Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGP-VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192 Query: 695 PSPSPV------GSPASVAQSRS-GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747 P P P+ G P ++ GP+ P PG PR P G + + P S+ Sbjct: 1193 P-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG----PRGPQGPNGA-DGPQGPPGSVG 1246 Query: 748 QDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807 G ++ +PG A +P P G+ G ++ G GP G GP G Sbjct: 1247 SVGGVGEKG---------EPGEAGNPGPP--GEAGVGGPKGERGEKGEAGPPGAA-GPPG 1294 Query: 808 GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGI--------PPYGTLPPGRMS 859 + P + P N G G P G G GQ G+ P PPG Sbjct: 1295 A--KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSG 1351 Query: 860 HASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSI-QNRPPGYPNM 918 A P GP PP +G G K + A + P G P Sbjct: 1352 EAG----PPGPPGKRGPPG-AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406 Query: 919 NQGGMMGTGPPYG-QGINSMAGMINPQGP--PYSMGGTMAN-NSAGMAASPEMMGLGDVK 974 G+ G P G QG+ AG P GP P + G + S G P ++GL Sbjct: 1407 E--GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---- 1460 Query: 975 LTPATKMNNKAD-GTPKTE 992 + P + K D G P T+ Sbjct: 1461 IGPPGEQGEKGDRGLPGTQ 1479 Score = 80.5 bits (197), Expect = 2e-14 Identities = 229/986 (23%), Positives = 299/986 (30%), Gaps = 188/986 (19%) Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGA-EPDL--KNSNGNAGPR---------- 110 GP P ++ + NG G G G G P EP + + G AGP Sbjct: 402 GPGVPAETDITE-TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQG 460 Query: 111 ---PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAA 167 P + PPG G +DG+ PP + P YG G + SA A A A Sbjct: 461 PTGPPGDPGDRGPPGRPGLPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQA 518 Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQN--SHDHGFPNHQYNSYYPNRSAYPPP 225 + Q + P +G G P GP + + G P Q R PP Sbjct: 519 ILQQARIALRGPPGPMGLTGRPG---PVGGPGSSGAKGESGDPGPQ-----GPRGVQGPP 570 Query: 226 APAYALSSPRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--GGPSAA 282 P G PG G A G + P + + F + G G Sbjct: 571 GPT--------GKPGKRGRPGADGGRGMPGEPGAK-------GDRGFDGLPGLPGDKGHR 615 Query: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342 G PQ P + + G +G PG GP+ +G Q A Sbjct: 616 GERGPQGPPGPPGDDGMRGEDGEIGPRGLPG---EAGPRGLLGPRGTPGAPGQPGMAGVD 672 Query: 343 AAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYS 402 + G Q P PG G G P P P+ G+ PQ G Sbjct: 673 GPPGPKGNMGPQGE----PGPPGQQGNPGP--QGLPGPQGPIGPPGEKGPQGKPGLAGLP 726 Query: 403 QQQGPPSGP----QQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ--------- 449 GPP P Q G P G Q P YP + + GL ++ Sbjct: 727 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 786 Query: 450 ----------------QIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQP 489 QI P G+ GP G G G Q + P P Sbjct: 787 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 846 Query: 490 PSQTPHAQPSYQQQPQSQPPQ----LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545 Q P + P + + + P Q+ P A P+ + + Sbjct: 847 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906 Query: 546 QSQPPYSQPQAQSPYQQQQP-------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598 P P + P Q P P P +P Q +T + + P Sbjct: 907 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP----GQRGETGFQGKTGP 962 Query: 599 PPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALS 658 P G + P G Q P + D P G G Sbjct: 963 PGPGGVVGPQGPTGETGPIGERGHPGPPGPP-GEQGLPGAAGKEGAKGDPGPQGISGKDG 1021 Query: 659 PGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVGSPASVAQS-RSGPLS 715 P +G+ GE+ P +P L G GP P PVGSP + +GP+ Sbjct: 1022 P----AGLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1072 Query: 716 PAAVPGNQMPPRP--------------PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761 PG Q PP P P+G+ D + P + A G + + Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR-DGVQGP-VGLPGPAGPAGSPGEDGDKGE 1130 Query: 762 YSSP-QPGS-----ALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG-----GQYGPQG--G 808 P Q GS P P G Q G G GP+G GQ G +G G Sbjct: 1131 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD-GEPGPRGQQGMFGQKGDEGARG 1189 Query: 809 YPRQPNYNALPNANYP--SAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR 866 +P P L P G G + PMG G PPG Sbjct: 1190 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG--------------PPGPRG------- 1228 Query: 867 PYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGT 926 P GPN A+ PQ G GG+ K + A N PG P G G Sbjct: 1229 PQGPNGAD-GPQGPPGSVGSVGGVGEKGEPGE-----AGN------PGPP-----GEAGV 1271 Query: 927 GPPYGQ-GINSMAGMINPQGPPYSMG 951 G P G+ G AG GPP + G Sbjct: 1272 GGPKGERGEKGEAGPPGAAGPPGAKG 1297 Score = 79.3 bits (194), Expect = 4e-14 Identities = 174/760 (22%), Positives = 235/760 (30%), Gaps = 105/760 (13%) Query: 32 REEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG-----GGGG 86 R E G E A G+ +GQ E +G P G + G + + G G G Sbjct: 807 RGEDGPEGPKGRAGPTGD-PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865 Query: 87 GAGSGGGPGAEPDLKNSNGNAGPRPALN-NNLTEPPGGGGGGSSDGVGAPPHSAAAALPP 145 G+ G G +P + G GPR + T PG G DG PP P Sbjct: 866 EKGARGVAG-KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 924 Query: 146 PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDH 205 GF P G P H G+ G GG + P GP + Sbjct: 925 GPVGFPGPKG--PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ-GPTGETGPI 981 Query: 206 GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSS 265 G H P P A G SG AG + P + + Sbjct: 982 GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041 Query: 266 FAQQRFGAMGGGGPSAAGG-----GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGP 320 + G G GP + G GT P P P A G +G PG GP Sbjct: 1042 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1100 Query: 321 QDGGAGKGPADMASQCWGAAAAAA-------AAAAASGGAQQRSHHAPM----------S 363 +GP + A + G + + P + Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1160 Query: 364 PGSSGGGGQPLART----------------PQPSSPMDQMGKMRPQPYGGTNPYSQQQGP 407 PG +GG G+P R P P P+ G P G N GP Sbjct: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220 Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGY----G 463 P P G P P G+ PQ P ++ ++GG+ + G GP G G Sbjct: 1221 PGPP--GPRGPQGPNGADGPQGPPGSV-----GSVGGVGEKGEPGEAGNPGPPGEAGVGG 1273 Query: 464 QQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS 523 +G+ + P P PP ++ PP P+ P + P Sbjct: 1274 PKGERGEKGEAGP-PGAAGPPGAKGPPGD---------DGPKGNPGPVGFPGDP------ 1317 Query: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583 PP + PA Q + P QP P + P P AA + + Sbjct: 1318 GPPGEPGPA---GQDGVGGDKGEDGDP-GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR 1373 Query: 584 SQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN-LSLQSRPSSLPDL 642 + + PP G P + K G E + + LP Sbjct: 1374 QGEKGAKGEAGAEGPP---------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424 Query: 643 SGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQ-SPFSPHTSPHLPGIRGPSPSPV 700 +G D P G G PG+ G S+GE+ +P P G RG P Sbjct: 1425 AGQ--DGPPGPMGP--PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-LPGTQ 1479 Query: 701 GSPASVAQSR----SGPLSPAAVPGNQMP-PRPPSGQSDS 735 GSP + +GPL P PG +P P+ P G S Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPG--LPGPQGPKGNKGS 1517 Score = 52.4 bits (124), Expect = 5e-06 Identities = 106/423 (25%), Positives = 139/423 (32%), Gaps = 95/423 (22%) Query: 648 DLPMGTEGALSPGVSTSGISSSQGEQSNPA-------QSPFSP------HTSPHLPGIRG 694 D P G +G + P G G+Q NP Q P P P L G+ G Sbjct: 672 DGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 727 Query: 695 PSPSPVGSPASVAQSRS-------GPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIA 747 + P G P QS GP P PG PR G +D + ++ Sbjct: 728 -ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG----PRGVKG-ADGVRGLKGSKGEKG 781 Query: 748 QD-----RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMG--SYQQNSMGSYGPQG 800 +D +G M + P P P G TG S Q G G G Sbjct: 782 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841 Query: 801 -----GQYGPQG--GYPRQPNYNALPNANYPSA-----GMAGGINPMGAGGQMH--GQPG 846 G+ GP+G G+P P N A + G G P G+ G G+PG Sbjct: 842 LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 901 Query: 847 IPPYGTLPPGRMSHASMGNRPYGPNMANMP--PQVGSGMCPPPGGMNRKTQETAVAMHVA 904 P GT S G+ P GP P PQ G P P G + + H Sbjct: 902 --PKGT---------SGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHPG 949 Query: 905 ANSI-----QNRPPGYPNMNQGGMMGT-------------------GPPYGQGINSMAGM 940 + PPG GG++G GPP QG+ AG Sbjct: 950 QRGETGFQGKTGPPG-----PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004 Query: 941 INPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP-KTESKSKKSS 999 +G P G + + AG+ P GL + P K G P S ++ S Sbjct: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGS 1064 Query: 1000 SST 1002 + T Sbjct: 1065 AGT 1067 Score = 48.9 bits (115), Expect = 6e-05 Identities = 112/521 (21%), Positives = 176/521 (33%), Gaps = 102/521 (19%) Query: 493 TPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYS 552 +P S + Q+Q PQ+ P + + ++ A Y +S T+ ++ + Sbjct: 240 SPDCDSSAPKAAQAQEPQIDEYAP---EDIIEYDYEYGEAEYKEAESVTEGPTVTEETIA 296 Query: 553 QPQAQ--SPYQQ------QQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELS 604 Q +A +Q+ + Q AP +S P P + + + + + ++ S Sbjct: 297 QTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNE-PNPVEEIFTEEYLTGEDYDSQRKNS 355 Query: 605 QDSFGSQAS----SAPSMTSSKGGQEDMN--LSLQSRPSSLPDLSGSIDDLPMGTEGALS 658 +D+ + + G+ D + +P+S P+ +P T+ Sbjct: 356 EDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFG-PGVPAETD-ITE 413 Query: 659 PGVSTSGISSSQGEQSNPA-----------QSPFSPHTSPHLPGIRGPSPSPVGSPASVA 707 ++ G +G++ PA P P PG++GP+ P G P Sbjct: 414 TSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPGDPGD-- 470 Query: 708 QSRSGPLSPAAVPGNQMPPRPPS-------------GQSDSIMHPSMNQSSIAQDRGYMQ 754 GP +PG P PP + +I +I Q Sbjct: 471 ---RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIAL 527 Query: 755 RNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQ 812 R P P + +PG P GG +G + G GPQG G GP G + Sbjct: 528 RGPPGPMGLTGRPG-------PVGGPGSSGA----KGESGDPGPQGPRGVQGPPGPTGK- 575 Query: 813 PNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNR-PYGPN 871 P P A+ GM G G G G PG+P G H G R P GP Sbjct: 576 PGKRGRPGAD-GGRGMPGEPGAKGDRG-FDGLPGLP-------GDKGHR--GERGPQGPP 624 Query: 872 MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPN-MNQGGMMGT-GPP 929 PPG + ++ + P G P G++G G P Sbjct: 625 -------------GPPGDDGMRGEDGEIG-----------PRGLPGEAGPRGLLGPRGTP 660 Query: 930 YGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 G MAG+ P GP +MG G +P GL Sbjct: 661 GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701 Score = 45.8 bits (107), Expect = 5e-04 Identities = 71/258 (27%), Positives = 87/258 (33%), Gaps = 58/258 (22%) Query: 7 PAAASSLGNPPPP----PP----SELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES 58 P + G P PP PP +E ++ E+ + EAG E G A Sbjct: 1347 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406 Query: 59 EGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR--PALNNN 116 EG G P P+G++ GA G G G G PG P LK G+ G + P L Sbjct: 1407 EG-LRGIPGPVGEQGLPGA----AGQDGPPGPMGPPGL-PGLKGDPGSKGEKGHPGL-IG 1459 Query: 117 LTEPPGGGGGGSSDGV----GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172 L PPG G G+ G+P +P PA G P Sbjct: 1460 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP------------------- 1500 Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPP-----PAP 227 PGL Q G G + GP D G P P S PP P P Sbjct: 1501 ----GPPGLPGPQ--GPKGNKGSTGPAGQKGDSGLPG-------PPGSPGPPGEVIQPLP 1547 Query: 228 AYALSSPRGGTPGSGAAA 245 + R T G A A Sbjct: 1548 ILSSKKTRRHTEGMQADA 1565 Score = 40.8 bits (94), Expect = 0.015 Identities = 56/201 (27%), Positives = 67/201 (33%), Gaps = 13/201 (6%) Query: 791 NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPY 850 N G+YG +G Q G P L AG AG + P G G G PG P Sbjct: 417 NGHGAYGEKG-----QKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPT-GPPG-DPG 469 Query: 851 GTLPPGRMSHASMGNRPYGPN-MANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQ 909 PPGR P P M +P + G P ++ Q A+ A Sbjct: 470 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ--ARIAL 527 Query: 910 NRPPGYPNMNQGGMMG-TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMM 968 PPG M G G G P G +G PQGP G G P Sbjct: 528 RGPPG--PMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585 Query: 969 GLGDVKLTPATKMNNKADGTP 989 G + P K + DG P Sbjct: 586 GGRGMPGEPGAKGDRGFDGLP 606 Score = 40.8 bits (94), Expect = 0.015 Identities = 106/513 (20%), Positives = 147/513 (28%), Gaps = 79/513 (15%) Query: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186 Q K PP P G + GPQ P + + E G PP P P Q LPG + G Sbjct: 957 QGKTGPPGPGG---VVGPQGPTGETGPIGERGHPGPPGP---PGEQ--GLPG-----AAG 1003 Query: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246 + A D ++ G+ G + + P Sbjct: 1004 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP-------------- 1049 Query: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYG--GPYDRVRTEPGIGPEGNMSTGA 1304 QGP G +G P R + G + + P + P G GP GP+G Sbjct: 1050 ---QGPPGPVGSPGERGSAGTAGPIGL-PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105 Query: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP--------------- 1349 Q + P SP + + + + S G++ G P Sbjct: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDK-GENGPPGPPGLQGPVGAPGIA 1164 Query: 1350 --SGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP 1407 G P P Q M+ Q+ R G GPP + P G+ PP Sbjct: 1165 GGDGEPGPRGQQGMFGQKGDEGAR---GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221 Query: 1408 AQPQPASQQ----QAAQPSPQQDVYNQYGNAYPATATAATERRP-----AGGPQNQF--- 1455 P P Q P V + G A P GGP+ + Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281 Query: 1456 -----PFQFGRDRVSAPPGTNAQQNMPPQM----MGGPIQASAEVAQQGTMWQGRNDMTY 1506 P G PPG + + P + GP Q G D Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1341 Query: 1507 NYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPP--YGPSAPVPPM 1564 P G + R +G+ G PP GP P P Sbjct: 1342 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPA 1401 Query: 1565 TRPPPSNYQ--PPPSMQNHIPQVSSPAPLPRPM 1595 +P P + P P + +P + P PM Sbjct: 1402 GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1434 Score = 37.7 bits (86), Expect = 0.13 Identities = 127/570 (22%), Positives = 167/570 (29%), Gaps = 115/570 (20%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQ-IPPLPGM----------- 1179 PP PAG + GP Q + + GD PP P + +P PG Sbjct: 443 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 502 Query: 1180 -SRSNSVGIQDAFNDGSDSTFQKRN----------SMTPNPGYQPSMNTSDMMGRMSYEP 1228 S+ ++ Q+A + + Q+ +T PG +S G Sbjct: 503 GSKGPTISAQEA---QAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 559 Query: 1229 NKDPYGSM-RKAPGSDPFMSSGQGPNGGMGDPYSRAAG--------PGLGNVAMGPRQHY 1279 + P G P P G +GG G P A PGL + Sbjct: 560 PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG 619 Query: 1280 PYGGP----YDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334 P G P D +R E G IGP G P+ G+ P P Q Sbjct: 620 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR----------GLLGPRGTPGAPGQPGMA 669 Query: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394 D G P G P P Q Q P G GPP ++ Sbjct: 670 GVDGPPGPKGNMG-PQGEPGPPGQ--QGNPGPQGLPGP-QGPIGPPGEKGP--------- 716 Query: 1395 TGQGQPQQQQLPPAQPQPASQQQAAQ---------PSPQQDVYNQYGNAYPATATAATER 1445 QG+P LP A P + Q P PQ + G P A Sbjct: 717 --QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----GYPGPRGVKGADGV 770 Query: 1446 RPAGGPQNQ-----FP-------FQFGRDRVS--APPGTNAQQNMPPQMMGGPIQASAEV 1491 R G + + FP + R V P G + + P+ GP Sbjct: 771 RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG--PKGRAGPTGDPGPS 828 Query: 1492 AQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPS-HGT 1550 Q G + Y RQ + P + G N ++ A P G Sbjct: 829 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN-------GEKGARGVAGKPGPRGQ 881 Query: 1551 RQP--PYGPSAPVPPMTRPPPSNYQ----PPPSMQNHIPQ-VSSPAPLPRPMENRTSPSK 1603 R P P G P +P P PP PQ P P P P K Sbjct: 882 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 941 Query: 1604 SPFL-HSGMKMQ-----KAGPPVPASHIAP 1627 H G + + K GPP P + P Sbjct: 942 DGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971 Score = 37.7 bits (86), Expect = 0.13 Identities = 86/381 (22%), Positives = 121/381 (31%), Gaps = 50/381 (13%) Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV-GIQDAF 1191 P AG GP E G L PP P P G+ ++ V G++ + Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP--IGYPGPRGVKGADGVRGLKGSK 777 Query: 1192 NDGSDSTFQKRNSMTPNPGYQPSMNTS---DMMGRMSYEPNKDPYGSM-RKAPGSDPFMS 1247 + + F PG++ M +G++ P G R P DP S Sbjct: 778 GEKGEDGF---------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 828 Query: 1248 SGQGPNGGMGDP----YSRAAG-------PGLGNVAMGPRQHYPYGGPYDRVRTEPGIGP 1296 G G +G P Y G PG G P R + P GP Sbjct: 829 GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP-TGP 887 Query: 1297 EGNMSTGAPQPNLMPS-NPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFP 1355 G S GA P P SG P P ++ Q Q + P G P P Sbjct: 888 RG--SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG-------PKGPPGP 938 Query: 1356 SQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQ 1415 + + Q + G GPP G + TG+ P ++ P P P + Sbjct: 939 PGKDGLPGHPGQRGETGFQGKTGPPG---PGGVVGPQGPTGETGPIGERGHPGPPGPPGE 995 Query: 1416 QQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQN 1475 Q + ++ P + + PAG FP + G PG + Sbjct: 996 QGLPGAAGKEGAKGD-----PGPQGISGKDGPAG--LRGFPGERGLPGAQGAPGLKGGEG 1048 Query: 1476 MPPQMMGGPIQASAEVAQQGT 1496 PQ GP+ + E GT Sbjct: 1049 --PQGPPGPVGSPGERGSAGT 1067 Score = 34.3 bits (77), Expect = 1.4 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 14/88 (15%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDL---KPPTPASTPHSQIPPLPGMS----RSNS 1184 PP P G QGP+ + ++ + GD PP P I PLP +S R ++ Sbjct: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1558 Query: 1185 VGIQ-DA------FNDGSDSTFQKRNSM 1205 G+Q DA ++DG + F NS+ Sbjct: 1559 EGMQADADDNILDYSDGMEEIFGSLNSL 1586 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 101 bits (251), Expect = 1e-20 Identities = 253/1051 (24%), Positives = 321/1051 (30%), Gaps = 162/1051 (15%) Query: 16 PPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQD 75 PP PP S K Q ++ G + + GQ GPP LG Q Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514 Query: 76 GAESNGGGGG--GGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDG 131 G + G G G G G PGA P K G+ P + + E G G Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574 Query: 132 VGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGG 191 G P LP P G+P G F + G +PGL L G Sbjct: 575 PGTPGQDGLPGLPGPK---GEPGG-----------ITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 192 LEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPA--PAYALSSP-RGGTPGS-GAAAAA 247 P GP + G N P + P P P ++ P + G PG+ G Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGN---PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 248 GSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG 307 G P ++ G G G P G P P P + P A G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPPGPKGFPGI----PGPPGAPG 728 Query: 308 YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP--- 364 G G + GP KG A A G R P P Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788 Query: 365 ----------GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ----------- 403 G G GQP P + G P P G P Q Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP--PGPPGIPGPIGQPGLHGIPGEKG 846 Query: 404 QQGPPS----GPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQ-QIPPYGQQG 458 GPP GP G PG P G+ P P + ++ G T+ ++ G G Sbjct: 847 DPGPPGLDVPGPPGERGSPGIP-GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG 905 Query: 459 PSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPP 517 P G G G++ + Q QP + +P P P L S+ Sbjct: 906 PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 518 YSQQPSQP--PHQQSPAPY------PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA 569 + P P P P Y P Q + Q PP + P Q P Sbjct: 966 KGE-PGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024 Query: 570 PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMN 629 +P PQ + PP GS P + KG + D Sbjct: 1025 LKGTIGDMGFPGPQGVEG----------PPGPSGVPGQPGS-----PGLPGQKGDKGDPG 1069 Query: 630 LSLQSRPSSLPDLSGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQSPFSPHTS-- 686 +S LP L G P G G PG GI S G+ P P +P Sbjct: 1070 IS----SIGLPGLPG-----PKGEPGL--PGYPGNPGIKGSVGDPGLPGL-PGTPGAKGQ 1117 Query: 687 PHLPGIRG----PSPSPVGSPASVA--QSRSGPLSPAAVPGNQMPP--RPPSGQSDSIMH 738 P LPG G P P + P GP+ PG PP + GQ D I Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ-DGIPG 1176 Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSPQ-----PGSALSPRQPSGGQIHTGMGSYQQNSM 793 P+ + Q P +P S + PG +P P G + G + Sbjct: 1177 PAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP-GPKGEPGFHGFP-GVQ 1234 Query: 794 GSYGPQG----------GQYGPQG--GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQM 841 G GP G G GPQG G P + LP P G+ G G G Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPP-GLPGNGGIKGEKGNP 1293 Query: 842 HGQPGIPPYGTLP-----------PGRMSHASMGNRPYGPNMANMPPQVG-SGMCPPPGG 889 GQPG+P L PGR M P P + P G SG+ PG Sbjct: 1294 -GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV---PGS 1349 Query: 890 MNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMM---GTGPPYGQGINSMAGMINPQGP 946 + + + PPG P + ++ GPP G + G+ PQGP Sbjct: 1350 AGPEGEPGLIG--------PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP 1401 Query: 947 PYSMGGTMANNSAGMAASPEMMGLGDVKLTP 977 G T G P G G K P Sbjct: 1402 QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1432 Score = 95.1 bits (235), Expect = 7e-19 Identities = 208/882 (23%), Positives = 264/882 (29%), Gaps = 162/882 (18%) Query: 60 GPAVGPPQPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAG------ 108 GP P Q + + + G N G G G G G PG P + S G G Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGL-PGIPGSKGEPGIPGIGL 708 Query: 109 ---PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAA 165 P P + PPG G G+ PP P GF P P + Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768 Query: 166 AAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP 225 A+ + G P G GL+ GP+ + +G P P PP Sbjct: 769 GALGPKGDRGFPGPP----GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP 824 Query: 226 APA-----------YALSSPRG----------GTPGS----GAAAAAGSKPPPSSSASAS 260 P + + +G G PG G A G PP S Sbjct: 825 GPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884 Query: 261 SSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLN--------QLLTSPSSARGYQG 310 + +S G MG GP G G P + P L L P+ +G +G Sbjct: 885 KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944 Query: 311 YPGGDYSGGPQD----GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGS 366 PG GP D G G+ G + Q P PG Sbjct: 945 EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004 Query: 367 SGGGGQP-------LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP----QQGH 415 G G P L P + MG PQ G S G P P Q+G Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Query: 416 ------------------------GYPGQP-----YGSQTPQRYPMTMQGRAQSAMGGLS 446 GYPG P G P T + Q + G Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124 Query: 447 YTQQIP-PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505 T P P G GP G P HP Q PP + P Q P+ Q+ Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184 Query: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQ-PQAQSPYQQQQ 564 QP P Q P P P+ +P + P Q P Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPG-IPGNPGLPG--PKGEPGFHGFPGVQGP--PGP 1239 Query: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGG 624 P P P+ L P PQ + Q P P+ P + + G Sbjct: 1240 PGSPGPA-LEGPKGNPGPQGPPGRPGPTGFQGLPGPE------------GPPGLPGNGGI 1286 Query: 625 QEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPH 684 + + Q LP L G D P G +G +PG G++ +G+ P Sbjct: 1287 KGEKGNPGQPGLPGLPGLKG--DQGPPGLQG--NPG--RPGLNGMKGDPGLPGV------ 1334 Query: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744 P PG++GPS P G P PG PP PP + PS Sbjct: 1335 --PGFPGMKGPSGVP------------GSAGPEGEPGLIGPPGPP-----GLPGPSGQSI 1375 Query: 745 SIAQDRGYMQRNPQMPQYSSPQPG--SALSPRQPSGGQIHTG-MGSYQQNSMGSYGPQGG 801 I D G P QPG P+ P G TG G +N + + GG Sbjct: 1376 IIKGDAG--------PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1427 Query: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHG 843 + G G P QP L P G+ G P G HG Sbjct: 1428 RKG-DPGLPGQPGTRGLDGPPGPD-GLQGPPGPPGTSSVAHG 1467 Score = 94.4 bits (233), Expect = 1e-18 Identities = 243/1052 (23%), Positives = 324/1052 (30%), Gaps = 168/1052 (15%) Query: 13 LGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKE 72 L P P + E+ Q+ + G R G++ G P G+ Sbjct: 314 LPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373 Query: 73 LQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGV 132 G + G G + GP P G G ++ PPG G + G+ Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL 433 Query: 133 GAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGL 192 PP A + PP+ +P P + + G + G G G Sbjct: 434 PGPPGPAGPHI-PPSDEICEP--GPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG-- 488 Query: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGS-GAAAAAGS 249 +GP G P + +P + A A + P+G G PG+ GA GS Sbjct: 489 --ISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA---TGPKGLPGIPGAPGAPGFPGS 543 Query: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--GTPQPTATPTLNQLLTSPSSAR- 306 K P + G +G G G GTP P L P Sbjct: 544 KGEPGDILTFPGMKGD-----KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Query: 307 -------GYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH 359 G G PG + GP G G GP + A G + Sbjct: 599 KGERGPPGNPGLPGLPGNIGPM-GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 360 APMSPGSSGGGGQP-------LARTP----QPSSPMDQMGKMRPQPYGGTNPYSQQQGPP 408 PG G G P L P QP P K P G P GPP Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP-----GPP 712 Query: 409 SGPQQGHGYPGQPYGSQTPQRYPMT----------MQGRAQSAMGGLSYTQQIP------ 452 GP+ G PG P TP R + +G A+ G +P Sbjct: 713 -GPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771 Query: 453 -PYGQQG-PSGYGQQGQTPYYNQQSPH----PQQQQPPYS---------QQPPSQTPHAQ 497 P G +G P G G+T P P Q P Q PP Sbjct: 772 GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSP----APYPSQQSTTQQHPQSQPPYSQ 553 P Q P + PP P P + SP AP P + P Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 554 PQAQSPY-QQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612 P + P P P + ++ P + Q Q P P Sbjct: 892 PGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ---GQPGLPGP------------ 936 Query: 613 SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL-SPGV-STSGISSSQ 670 T KG + + LP G +D +G++G PG+ G+S + Sbjct: 937 ------TGEKGSKGE---------PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Query: 671 GEQSNPAQSPFSPHTS--PHLPGIRGPSPSP--VGSPASVA----------------QSR 710 G Q P P P S P LPG GP +P G P + Q Sbjct: 982 GYQGLPG-DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040 Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSA 770 GP P+ VPG P P GQ P ++ + G + P +P Y PG Sbjct: 1041 EGPPGPSGVPGQPGSPGLP-GQKGDKGDPGISSIGLPGLPG-PKGEPGLPGYPG-NPGIK 1097 Query: 771 LSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQG--GYPRQPNYNALPNANYPSAGM 828 S P + G+ Q + + G GP+G G P P G+ Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP-------------GL 1144 Query: 829 AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPG 888 G P+G GG GQPG PPG P P Q G G PPG Sbjct: 1145 PGEPGPVGGGGH-PGQPG-------PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 889 --GMNRKTQETAVAMHVAANSIQNRPPGYPNMNQ-GGMMG-TGPP--YGQGINSMAGMIN 942 G++ + + + + N P G P + G+ G GPP G + G Sbjct: 1197 LPGLSGQKGDGGLP-GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255 Query: 943 PQGPPYSMGGTMANNSAGMAASPEMMGLGDVK 974 PQGPP G T G P + G G +K Sbjct: 1256 PQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIK 1287 Score = 73.2 bits (178), Expect = 3e-12 Identities = 222/979 (22%), Positives = 289/979 (29%), Gaps = 197/979 (20%) Query: 76 GAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVG 133 G++ + G G G G PG E P L G GP PG G DG+ Sbjct: 35 GSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGP-----------PGPRGQKGDDGIP 83 Query: 134 APPHSAAAALPPPAYGF-------GQP-YGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQ 185 PP PP GF G P + +P + G SPG LQ Sbjct: 84 GPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQ 143 Query: 186 SGGGG-GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGS--- 241 G G+ G + P + N YP P L P G PG Sbjct: 144 GPPGPPGIPGMKGEPGSIIMSSLPGPKGNP------GYPGPPGIQGLPGPTG-IPGPIGP 196 Query: 242 -GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 G G PP + +F + G G G G P P + + Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPK-GEKGEQGLQ----GPPGPPGQISEQKRPI 251 Query: 301 SPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHA 360 +G QG PG GP +GP G + + Sbjct: 252 DVEFQKGDQGLPG---DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308 Query: 361 PMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQ 420 P PG G G P P Q G P G G G + G PG Sbjct: 309 PGIPGLPGDPGYP--GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 421 PY--------GSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472 P G Q P P G + + G +GP G G P + Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP-PGLD 425 Query: 473 QQSPHPQQQQPPYSQQP--PSQTPHAQPSYQQQPQSQPPQ-LQSSQ-------------- 515 Q P PP P P +P P S + LQ Q Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCI 485 Query: 516 -PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA-PSTL 573 S P QP P P S Q+ + Q + P+ P P P P + Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGL-PGIPGAPGAPGFPGSK 544 Query: 574 SQQA---AYPQPQSQQSQQTAYSQQRFPP-PQELSQDSFGSQASSAPSMTSSKGGQEDMN 629 + +P + + + + P P QD P + KG + Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL-------PGLPGPKGEPGGIT 597 Query: 630 LSLQSRPSSLPDLSGSIDDL-PMGTEGALSPG-VSTSGISSSQGEQSNPAQ--------S 679 + P P L G ++ PMG G PG V GI QG NP Q Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI---QGVAGNPGQPGIPGPKGD 654 Query: 680 PFSPHTSPHLPGIRGPS-----------------------PSPVGSPASVAQSRSGPLSP 716 P T P PG+ G P G P GP P Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP 714 Query: 717 AAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPR 774 PG PP P R ++ P P + P +PG AL P Sbjct: 715 KGFPGIPGPPGAPG----------------TPGRIGLEGPPGPPGFPGPKGEPGFAL-PG 757 Query: 775 QPSGGQIHTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGI 832 P G+ ++ G+ GP+G G GP G P + + LP G G + Sbjct: 758 PPGP----PGLPGFK----GALGPKGDRGFPGPPGP-PGRTGLDGLP-------GPKGDV 801 Query: 833 NPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGS-GMCPPPGGMN 891 P G G M G PG+P G P P +P +G G+ PG Sbjct: 802 GPNGQPGPM-GPPGLPGIGVQGP--------------PGPPGIPGPIGQPGLHGIPG--- 843 Query: 892 RKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMG 951 + PG P G+ GPP +G + G P GPP S G Sbjct: 844 -----------------EKGDPGPP-----GLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Query: 952 GTMANNSAGMAASPEMMGL 970 ++G + MG+ Sbjct: 882 LPGKAGASGFPGTKGEMGM 900 Score = 65.9 bits (159), Expect = 4e-10 Identities = 234/1043 (22%), Positives = 312/1043 (29%), Gaps = 218/1043 (20%) Query: 5 VAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVG 64 + P L PP PP K G E+GE Q +GP G Sbjct: 194 IGPPGPPGLMGPPGPPGLPGPKGNM-------GLNFQGPKGEKGE------QGLQGPP-G 239 Query: 65 PP-------QPLGKELQDGAESNGGGGG-----GGAGSGGGPGAEPDLKNSNGNAGPRPA 112 PP +P+ E Q G + G G G G G PG E K G G R Sbjct: 240 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK 299 Query: 113 LNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQ 172 PG G G+ P P Y G+P GR Sbjct: 300 --------PGKDGENGQPGIPGLPGD-------PGYP-GEP-GRDGEKGQKGDT------ 336 Query: 173 HGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYP--PPAPAYA 230 G PGL + G G + G + N G P + +P P P P A Sbjct: 337 -GPPGPPGLVIPRPGTGITI----GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391 Query: 231 LSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG------ 284 + P G G G + PP S + GA G GP G Sbjct: 392 VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG----QPGAPGLPGPPGPAGPHIPPS 447 Query: 285 ------GTPQPTATPTLNQLLTSPSSARGYQGYP-----GGDYSGGPQDGGAGKGPADMA 333 G P P +P ++ L +G +G G SG P G P Sbjct: 448 DEICEPGPPGPPGSPG-DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506 Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQ 393 S + A A+G P PG+ G G P ++ +P + G + Sbjct: 507 SLGFPGQKGEKGQAGATG-----PKGLPGIPGAPGAPGFPGSKG-EPGDILTFPGMKGDK 560 Query: 394 PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453 G+ G P P Q G PG P P+ P + + + G +P Sbjct: 561 GELGSPGAPGLPGLPGTPGQD-GLPGLP----GPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 454 -YGQQGPSGYGQQGQTPYYNQQ--SPHPQQQQPPYSQQPPSQ--TPHAQPSYQQQPQSQP 508 G GP G+G G Q + +P Q P + P Q T +P P Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 509 PQLQSSQPPYSQQPSQP--PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ 566 P QP P P + P P+ P P Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG---------- 725 Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626 AP T + P FP P+ G+ Sbjct: 726 --APGTPGRIGLEGPP----------GPPGFPGPK----------------------GEP 751 Query: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG-----VSTSGISSSQGEQS-NPAQSP 680 L P LP G++ P G G P G+ +G+ N P Sbjct: 752 GFALPGPPGPPGLPGFKGALG--PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP 809 Query: 681 FSPHTSPHLPGI--RGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH 738 P P LPGI +GP P P G P + Q +PG + P PP Sbjct: 810 MGP---PGLPGIGVQGP-PGPPGIPGPIGQP-----GLHGIPGEKGDPGPPG-------- 852 Query: 739 PSMNQSSIAQDRGYMQRNPQMPQYSSP--QPGSALSPRQPSGGQIHTGMGSYQQNSMGSY 796 ++ +RG +P +P P PGS P + G MG Sbjct: 853 --LDVPGPPGERG----SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE-----MGMM 901 Query: 797 GPQGGQYGPQGGYPRQPNYNALPNANYPSA--GMAGGINPMGAGGQMHGQPGIPPYGTLP 854 GP G GP G P + +P G G P G G G+PG+P P Sbjct: 902 GPPGPP-GPLG----IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK-GEPGLPG----P 951 Query: 855 PGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRP-- 912 PG P PN+ + G P G++ Q P Sbjct: 952 PG----------PMDPNLLGSKGEKGEPGLPGIPGVS------------GPKGYQGLPGD 989 Query: 913 PGYPNMN-QGGMMGT-GPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 PG P ++ Q G+ G GP G+ G+I P G ++G G+ P G+ Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 971 GDVKLTPATKMNNKADGTPKTES 993 +P G P S Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISS 1072 Score = 36.2 bits (82), Expect = 0.38 Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 7/127 (5%) Query: 53 AAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAE--PDLKNSNGNAGPR 110 +AG E E +GPP P G G G G G G PG + P + G GP Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408 Query: 111 ----PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF-GQPYGRSPSAVAAAA 165 N L G GG G+ P + PP G G P S+VA Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGF 1468 Query: 166 AAVFHQQ 172 H Q Sbjct: 1469 LITRHSQ 1475 Score = 34.3 bits (77), Expect = 1.4 Identities = 75/339 (22%), Positives = 105/339 (30%), Gaps = 50/339 (14%) Query: 1109 RGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPAST 1168 +G PP I S P P G+ GP Q G + PP P Sbjct: 143 QGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202 Query: 1169 PHSQIPP-LPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPS-----MNTSDMMG 1222 PP LPG + + Q + + Q P P Q S ++ G Sbjct: 203 MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRPIDVEFQKG 258 Query: 1223 RMSYEPNKDPYG--SMRKAPGSDPFMSSGQGPNGGMGDPYSRA--------AGPGLGNVA 1272 ++ P G +R PG +G G G+P R PG+ + Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPP---GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315 Query: 1273 MGPRQHYPYGGPYDRVRTEPG-IGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQ 1331 P YP D + + G GP G P+P + + G P ++ ++ Sbjct: 316 GDP--GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373 Query: 1332 QQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNY--KRPMDGTYGPPAKRHEGEMY 1389 F P G P P M + +R G GPP Sbjct: 374 ----------GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-------I 416 Query: 1390 SVPYSTG-QGQPQQQQLP----PAQPQPASQQQAAQPSP 1423 S+P G GQP LP PA P + +P P Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455 Score = 31.6 bits (70), Expect = 9.4 Identities = 75/346 (21%), Positives = 109/346 (31%), Gaps = 56/346 (16%) Query: 1122 DSKKSQPKIQPPS----PAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPA----STP--HS 1171 D + QP + P+ G + GP P + ++G +P P S P + Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 1172 QIPPLPGM-SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNK 1230 +P PG S G+ + + + PG + ++ G E Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 1231 DPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAG----------PGLGNVAMGPRQHYP 1280 P G PG P G G GDP + G PGL P Sbjct: 1045 GPSG----VPGQ-PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGS 1099 Query: 1281 YGGP-------YDRVRTEPGI-------GPEGNMSTGAPQPNL-MPSNPD---SGMYSPS 1322 G P + +PG+ GP G P N +P P G + Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159 Query: 1323 RYPPQQQQQQQQRHDSYGNQFSTQGTPS----GSPFPSQQTTMYQQQQQNYKRPMDGTYG 1378 PP ++ + Q D +G P G+P P + Q+ + G G Sbjct: 1160 PGPPGEKGKPGQ--DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG 1217 Query: 1379 PPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424 P + E + P QG P PP P PA + P PQ Sbjct: 1218 LPGPKGEPGFHGFPGV--QGPPG----PPGSPGPALEGPKGNPGPQ 1257 >gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] Length = 2063 Score = 101 bits (251), Expect = 1e-20 Identities = 174/721 (24%), Positives = 247/721 (34%), Gaps = 118/721 (16%) Query: 353 AQQRSHHAPMS-PGSSGGGGQPLARTPQPSSP----MDQMGKMRPQPYGGTNPYSQQQGP 407 AQ RS M+ P +G + A P S P M+ + P G N S P Sbjct: 140 AQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPP--GGNVSSSMMAP 197 Query: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ 467 P+ QP +TP+ P + + GL QQ P G P + Q Sbjct: 198 GPNPEL------QP---RTPR--PASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPV 246 Query: 468 TPYYNQQS-----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522 + N+Q P QQQQ QQ Q Q QQQ Q++PPQ Q P +P Sbjct: 247 S--VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRP 304 Query: 523 SQPPHQQSPAP--YPSQQSTTQQHPQSQ---------PPYSQPQAQSPYQQQQPQQPAPS 571 Q P P + S Q P +Q + + P QQQ +P+ + Sbjct: 305 QFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA 364 Query: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631 T+ + P P SQQ + + FP Q +AP M S +GG + Sbjct: 365 TVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQ-------FTAPQMKSLQGGPSRVPTP 417 Query: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPG 691 LQ P L+ + P + + G S SS Q+ P P +P G Sbjct: 418 LQQ-----PHLT---NKSPASSPSSFQQG---SPASSPTVNQTQQQMGPRPPQNNPLPQG 466 Query: 692 IRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751 + PV SP + G + P + Q PP Q +HP + G Sbjct: 467 FQ----QPVSSPGRNPMVQQGNVPPNFMVMQQQPP----NQGPQSLHPGLGGMPKRLPPG 518 Query: 752 YM--QRNP-----QMPQYSSPQPGSALSPR-------QPSGGQ-----------IHTGMG 786 + Q NP Q+P ++ PG++ +P+ Q +GGQ H Sbjct: 519 FSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPN 578 Query: 787 SYQQNSMGSYGPQGGQYGPQGGYPR--QPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844 Q + MG +G Q G P+ N P PS M + + GQM Q Sbjct: 579 MMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQ 638 Query: 845 PG-IPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------------QVGSGMCPPPGGM 890 G + P + R G P N+ P Q G M P M Sbjct: 639 QGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQM 698 Query: 891 -----NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPY---GQGINSMAGMIN 942 Q+ + + N +Q + NQ +M GP G N M+ Sbjct: 699 MGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVM-PGPAQIMRGPTPNMQGNMVQ 757 Query: 943 PQGPPYSMGGTMANNSAGMAASP-EMMGLGDVKLTPATKMNNKAD--GTPKTESKSKKSS 999 G M G M + SP ++MG+ L P + A G P T + + S Sbjct: 758 FTG---QMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSL 814 Query: 1000 S 1000 S Sbjct: 815 S 815 Score = 100 bits (250), Expect = 1e-20 Identities = 335/1574 (21%), Positives = 496/1574 (31%), Gaps = 351/1574 (22%) Query: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEG 60 + A+ + A + +PPPP P ++A Q + G+ A + +G Sbjct: 357 LQARPSLATVQTPSHPPPPYPFGSQQASQAHTN-------FPQMSNPGQFTAPQMKSLQG 409 Query: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNL--- 117 P PL Q + + G P + P + + GPRP NN L Sbjct: 410 GPSRVPTPLQ---QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQG 466 Query: 118 ---------------------------TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGF 150 +PP G G+G P PP + Sbjct: 467 FQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRL-----PPGFSA 521 Query: 151 GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSH--DHGFP 208 GQ + A G Q +Q GG G AGP QN HG P Sbjct: 522 GQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQG----AGPPQNQMQVSHGPP 577 Query: 209 NHQYNSY------YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASS- 261 N S N+ A P LS+ + G P G PPS Sbjct: 578 NMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQ-GQPQQG---------PPSQLMGMHQQ 627 Query: 262 ---SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG 318 S QQ+ G + P P ++ PS G P Sbjct: 628 IVPSQGQMVQQQ-GTLNPQNPMILSRAQLMPQG----QMMVNPPSQNLG----PSPQRMT 678 Query: 319 GPQDGGAGKGPADMA--SQCWGAAAAA----------AAAAAASGGAQQ--RSHHAPMSP 364 P+ + +GP MA +Q G G QQ + + + P Sbjct: 679 PPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMP 738 Query: 365 GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGP-PSGPQQGHGYPGQPYG 423 G + + R P P+ M + Q G P QQGP + P Q G GQ Sbjct: 739 GPA-----QIMRGPTPNM-QGNMVQFTGQMSGQMLP---QQGPVNNSPSQVMGIQGQVLR 789 Query: 424 SQTPQRYPMTMQG-RAQSAMGGLSYTQQIPPYGQQ-----GPSGYGQQGQTPYYNQQSPH 477 P + G A +A +S +Q +P Q P QG + N S H Sbjct: 790 PPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGH 849 Query: 478 PQQQQPPYS--------------------------------------------------- 486 P+S Sbjct: 850 GMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNT 909 Query: 487 --QQPPSQTPHAQPSYQQQ----PQSQPPQL-QSSQPPY---------SQQPSQPPHQQS 530 +P + P + QQ P ++P L ++ QPP + P P Sbjct: 910 NANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNR 969 Query: 531 PAPYPSQ---QSTTQQHPQS---------QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAA 578 P YPSQ Q QQ P QPP QPQ Q P QQQ P P + QQ Sbjct: 970 PPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQ 1029 Query: 579 YPQ-------PQSQQSQQTAYSQQRFPPPQELSQDSFG---SQASSAPSMTSSKGGQEDM 628 Q Q +S + SQ PP L+ DS Q+ S P M S +G Sbjct: 1030 QQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG----- 1084 Query: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688 P+S+P S +PM +P S S Q NP+ SP + S Sbjct: 1085 -------PASVPP-SPDKQRMPMPVN---TPLGSNSRKMVYQESPQNPSSSPLAEMAS-- 1131 Query: 689 LPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG-QSDSIMHPSMNQSSI 746 LP G +PS G P ++ P + + G + P P S Q + P +N S+ Sbjct: 1132 LPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVN--SL 1189 Query: 747 AQDRGYMQRNPQMP-QYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGP 805 G+ N P Q S P+ + SPR P Q + S S P+ Sbjct: 1190 PSSHGHHFPNVAAPTQTSRPKTPNRASPR-PYYPQTPNNRPPSTEPSEISLSPERLNASI 1248 Query: 806 QGGYPRQPNYNALPNANYPSAGMAGGINP--MGAGGQMHGQPGIPPYGTLPP-------- 855 G +P Q N P N G+NP + A GQ + P P Sbjct: 1249 AGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSV 1308 Query: 856 ----GRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNR 911 G+ S++ R N P P PG N K + +A A +QN Sbjct: 1309 VVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNV 1368 Query: 912 PPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYS---MGGTMANNSAGM------- 961 + + P G N+ +NPQ S +GG + +N + Sbjct: 1369 ELPRNVLVSPTPLANPPVPGSFPNNSG--LNPQNSTVSVAAVGGVVEDNKESLNVPQDSD 1426 Query: 962 ----AASPEMMGLGDVKLTPATKM-------NNKADGTPK--------TESKSKKSSSST 1002 + E + + ++K PA ++ +K DG P E+K+ S + Sbjct: 1427 CQNSQSRKEQVNI-ELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMR 1485 Query: 1003 TTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNL----PAVGRKPLDLYRLYVSV 1058 +++L + G P + K G+T+L P V + L + ++ Sbjct: 1486 EAPTSLSQLLDNSGAPNVTI-----------KPPGLTDLEVTPPVVSGEDLKKASVIPTL 1534 Query: 1059 KEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIF 1118 +++ +E + +LN+ S+ SSL + E + P I Sbjct: 1535 QDLSSS---------KEPSNSLNLPHSNELCSSLVHPELS---------EVSSNVAPSIP 1576 Query: 1119 AAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTP-HSQIPPLP 1177 S I P P ++ P +TS++ T A+ P H Q + Sbjct: 1577 PVMSRPVSSSSISTPLPPNQITVFVTSNPITTSAN----------TSAALPTHLQSALMS 1626 Query: 1178 GMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMR 1237 + + G + ++G + P + +N+S ++ M GS Sbjct: 1627 TVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVF---INSSSIIQVMK--------GSQP 1675 Query: 1238 KAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGI--- 1294 + P + N G+ P GP H P + P Sbjct: 1676 STIPAAPLTT-----NSGLMPPSVAVVGP----------LHIPQNIKFSSAPVPPNALSS 1720 Query: 1295 GPEGNMSTGAP-------QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG 1347 P N+ TG P P +PS P + +PP QQ ++ D Q +T Sbjct: 1721 SPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPP-VQQVKELNPDEASPQVNTSA 1779 Query: 1348 TPSGSPFPSQQTTM 1361 + P SQ TTM Sbjct: 1780 DQNTLP-SSQSTTM 1792 Score = 89.7 bits (221), Expect = 3e-17 Identities = 267/1210 (22%), Positives = 393/1210 (32%), Gaps = 229/1210 (18%) Query: 448 TQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQP--SYQQQPQ 505 T IPP G S +P P + P + +P SQ+ P S Q Sbjct: 181 TVMIPPGGNVSSS------------MMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQ 228 Query: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQP 565 P + P + QP Q +PA +P Q QQ Q Q Q Q QQQQ Sbjct: 229 QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQ------QQQQQQQQQQQ 282 Query: 566 QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625 QQ + QQ QPQ + Q TA P Q + S A ++G Sbjct: 283 QQQLQARPPQQHQQQQPQGIRPQFTA-------PTQVPVPPGWNQLPSGALQPPPAQGSL 335 Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 M + + + LP PM + P ++T Q+P P Sbjct: 336 GTMTANQGWKKAPLPG--------PMQQQLQARPSLAT-------------VQTPSHP-- 372 Query: 686 SPHLPGIRGPSPSPVGSP-ASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744 P P P GS AS A + +S PG P+ S Q PS + Sbjct: 373 ---------PPPYPFGSQQASQAHTNFPQMSN---PGQFTAPQMKSLQGG----PSRVPT 416 Query: 745 SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804 + Q P ++ P S+ S S+QQ S S P Q Sbjct: 417 PL-----------QQPHLTNKSPASSPS--------------SFQQGSPAS-SPTVNQTQ 450 Query: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGR---MSHA 861 Q G PR P N LP + + G NPM G + P PP + H Sbjct: 451 QQMG-PRPPQNNPLPQG-FQQPVSSPGRNPMVQQGNV--PPNFMVMQQQPPNQGPQSLHP 506 Query: 862 SMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQG 921 +G P +PP +G P + TA NS + N+ Sbjct: 507 GLGGMP-----KRLPPGFSAGQANPNFMQGQVPSTTATT---PGNSGAPQLQANQNVQHA 558 Query: 922 GMMGTGPPYGQGINSMAGMINPQGPPYSMG-------GTMANNSAGMAASPEMMGLGDVK 974 G G GPP Q M GPP M G M N AG + P++ L +++ Sbjct: 559 GGQGAGPPQNQ-------MQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQV-NLSNMQ 610 Query: 975 LTPATKMNNKADG-----TPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLA 1029 P ++ G P ++ + N I +L P+ +M V+ Sbjct: 611 GQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL--MPQGQMMVNPPSQ 668 Query: 1030 FTEEKAMGMTN-LPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSA 1088 MT + ++ + + + G + +N ++ TN G Sbjct: 669 NLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQ- 727 Query: 1089 ASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQ 1148 F + + P P + Q + + SG M Q P Sbjct: 728 --------------FNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773 Query: 1149 STSSSMA---EGGDLKPPTPASTPH-SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNS 1204 + S S +G L+PP P+ PH +Q P + +N V + D S Q+ N Sbjct: 774 NNSPSQVMGIQGQVLRPPGPS--PHMAQQHGDPATTANNDVSLSQMMPDVS---IQQTNM 828 Query: 1205 MTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDP----FMSSGQGPNGGMGDPY 1260 + P+ M G + + +G AP S MS GQ P G P Sbjct: 829 VPPH--------VQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNP----GFPV 876 Query: 1261 SR---AAGPGLGNVAMGPRQHYPYGGPYDRVRT---EPGIGPEGNMSTGAPQPNLMPSNP 1314 ++ P L N+ +G + T +P + Q P Sbjct: 877 NKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTR 936 Query: 1315 DSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMD 1374 +G+ + PP +Q +S P G +PSQ QQ Sbjct: 937 PAGLEEADQ-PPLPGEQGINLDNSGPKLPEFSNRPPG--YPSQPVEQRPLQQMP------ 987 Query: 1375 GTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNA 1434 P +H P Q Q QQQ PP QP SQQQ Q + + Sbjct: 988 ----PQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDP 1043 Query: 1435 YPATATAATERRPAGGPQN----QFPFQFG---------RDRVSAPPGTNAQQNMPPQMM 1481 + P GP N + P Q + S PP + Q+ P + Sbjct: 1044 KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQR--MPMPV 1101 Query: 1482 GGPIQASAE--VAQQGTMWQGRNDMTYNYANRQSTG----SAPQGP---AYHGVNRTDEM 1532 P+ +++ V Q+ + + + +++G S P GP H V +++ Sbjct: 1102 NTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQL 1161 Query: 1533 LHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLP 1592 + T G + P SA + PP N P S +H P V++P Sbjct: 1162 MMT-------------GPKPGPSPLSATQGATPQQPPVN-SLPSSHGHHFPNVAAPTQTS 1207 Query: 1593 RP-MENRTSP 1601 RP NR SP Sbjct: 1208 RPKTPNRASP 1217 Score = 63.9 bits (154), Expect = 2e-09 Identities = 155/683 (22%), Positives = 226/683 (33%), Gaps = 178/683 (26%) Query: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI 1173 PP + + SQ P + G PQ +GG + PTP PH Sbjct: 372 PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKS------LQGGPSRVPTPLQQPH--- 422 Query: 1174 PPLPGMSRSNSVGIQDAFNDGSDSTF----QKRNSMTPNP--------GYQ-----PSMN 1216 ++ + +F GS ++ Q + M P P G+Q P N Sbjct: 423 -----LTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRN 477 Query: 1217 TSDMMGRM--------SYEPNKDPY-------GSMRKAPGSDPFMSSGQ-GPNGGMGD-P 1259 G + PN+ P G ++ P P S+GQ PN G P Sbjct: 478 PMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLP---PGFSAGQANPNFMQGQVP 534 Query: 1260 YSRAAGPG-LGNVAMGPRQHYPYGG------PYDRVRTEPG---------IGPEGNM--- 1300 + A PG G + Q+ + G P ++++ G +G GNM Sbjct: 535 STTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQ 594 Query: 1301 ---STGAPQPNL--MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGT--PSGSP 1353 ++G PQ NL M P G P Q QQ S G QGT P Sbjct: 595 QAGTSGVPQVNLSNMQGQPQQGP------PSQLMGMHQQIVPSQGQMVQQQGTLNPQNPM 648 Query: 1354 FPSQQTTMYQQQQQNYKRPMDGTYGPPAKR---------HEGEMYSVPYST---GQGQPQ 1401 S+ M Q Q P GP +R +G P++ QGQ Sbjct: 649 ILSRAQLMPQGQMM--VNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVL 706 Query: 1402 QQQLPPAQPQPASQQQA------------AQPSPQQ----DVYNQYGNAYPATATAATER 1445 QQ P + +Q Q P P Q N GN T + + Sbjct: 707 LQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM 766 Query: 1446 RPAGGPQNQFPFQFG--RDRVSAPPGTN---AQQNMPP-----------QMMGG-PIQAS 1488 P GP N P Q + +V PPG + AQQ+ P QMM IQ + Sbjct: 767 LPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQT 826 Query: 1489 AEV-----AQQGTMWQGR----NDMTYN-------YANRQSTGSAPQGPAYHGVNRTD-- 1530 V A QG G + M++N N+ S G P P V T Sbjct: 827 NMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPL 886 Query: 1531 --EMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSP 1588 +L +D A H +G + P +PP +N +++P Sbjct: 887 LVNLLQSDISAGH-------------FGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTP 933 Query: 1589 APLPRPMENRTSPSKSPFLHSGMKMQKAGPPV----------PASHIAPAPVQ--PPMIR 1636 P +E P G+ + +GP + P+ + P+Q PP + Sbjct: 934 DTRPAGLEEADQPPLPG--EQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLM 991 Query: 1637 RDITFPP-GSVEATQPVLKQRRR 1658 + + PP + QP L Q+++ Sbjct: 992 QHVAPPPQPPQQQPQPQLPQQQQ 1014 Score = 58.5 bits (140), Expect = 7e-08 Identities = 98/407 (24%), Positives = 131/407 (32%), Gaps = 79/407 (19%) Query: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308 G G + M + A+GPG+ + P GG PG PE T P Sbjct: 154 GAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQ 213 Query: 1309 LMPSNP------------DSGMYSPSRYP---------------PQQQQQQQQRHDSYGN 1341 +P SG +P +P PQ QQQQQQ+ Sbjct: 214 SDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQ 273 Query: 1342 QFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQ 1401 Q Q ++ +QQQQ RP + P + VP Q Sbjct: 274 QQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQ---FTAPTQ------VPVPPGWNQLPSG 324 Query: 1402 QQQLPPAQ----PQPASQ--QQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQF 1455 Q PPAQ A+Q ++A P P Q Q A P+ AT T P Sbjct: 325 ALQPPPAQGSLGTMTANQGWKKAPLPGPMQ----QQLQARPSLATVQTPSHPPP------ 374 Query: 1456 PFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG 1515 P+ FG + S A N P G A + QG + + + +S Sbjct: 375 PYPFGSQQAS-----QAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPA 429 Query: 1516 SAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPP 1575 S+P + +GS S T P PP P P +Q P Sbjct: 430 SSPS-------------------SFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQP 470 Query: 1576 PSMQNHIPQVSSPAPLPRPM-ENRTSPSKSP-FLHSGM-KMQKAGPP 1619 S P V P M + P++ P LH G+ M K PP Sbjct: 471 VSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPP 517 Score = 50.4 bits (119), Expect = 2e-05 Identities = 243/1158 (20%), Positives = 377/1158 (32%), Gaps = 207/1158 (17%) Query: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 E + + QS L DL I + + EGA++ ++ + S + P + S Sbjct: 106 ERLRILAQSNNQQLRDLG--ILSVQIEGEGAINLALAQN--RSQDVRMNGPMGAGNSVRM 161 Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAV---PGNQMPPRPP--SGQSDSIMHPS 740 P GP + +PA+V G +S + + P ++ PR P + QSD+ M P Sbjct: 162 EAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDA-MDPL 220 Query: 741 MNQSSIAQDRGYMQRNPQ---MPQYSSPQPGSALSPRQPSG-GQIHTGMGSYQQNSMGSY 796 ++ I Q Q +P P + QP S P+ Q+ QQ Sbjct: 221 LSGLHIQQ-----QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQ------ 269 Query: 797 GPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPG 856 Q Q Q +Q A P + P G Q +P +PPG Sbjct: 270 --QQQQQQQQQQQQQQQQLQARPPQQHQQQ------QPQGIRPQFTAPTQVP----VPPG 317 Query: 857 --RMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPG 914 ++ ++ P ++ M G P PG M ++ Q V S + PP Sbjct: 318 WNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPS--HPPPP 375 Query: 915 YP-NMNQGGMMGTGPPY--GQGINSMAGMINPQGPPYSMGGTMAN---NSAGMAASPEMM 968 YP Q T P G + M + QG P + + + A+SP Sbjct: 376 YPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSF 435 Query: 969 GLGDVKLTPATKMNNKADGT-PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRY 1027 G +P + G P + + ++ + + G P M + + Sbjct: 436 QQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQ- 494 Query: 1028 LAFTEEKAMGMTNL-PAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSS 1086 + G +L P +G P L + + Q N N ++ + + Sbjct: 495 ----QPPNQGPQSLHPGLGGMPKRLPPGFSA-------GQANPNFMQGQVPSTTATTPGN 543 Query: 1087 SAASSLK-KQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAG-SGSMQGP 1144 S A L+ Q +Q +G PP + + P + PS G G+M Sbjct: 544 SGAPQLQANQNVQHAGG------QGAGPPQNQMQVSHGP---PNMMQPSLMGIHGNMNNQ 594 Query: 1145 QT-----PQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDG----- 1194 Q PQ S+M PP+ H QI P S+ V Q N Sbjct: 595 QAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVP----SQGQMVQQQGTLNPQNPMIL 650 Query: 1195 SDSTFQKRNSMTPNPGYQ----------PSMNTSDMMGRMSYEPNKDPYGS-----MRKA 1239 S + + M NP Q P G P+ G +++ Sbjct: 651 SRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQN 710 Query: 1240 PGSDPFMSSG-QGPNGGMGDPYSRAAGPGLGNVAMGPR----------------QHYPYG 1282 P + M++ QG PG + GP Q P Sbjct: 711 PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQ 770 Query: 1283 GPYD-----------RVRTEPGIGPEGNMSTGAPQP------NLMPSNPDSGMYSPSRYP 1325 GP + +V PG P G P +L PD + + P Sbjct: 771 GPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVP 830 Query: 1326 PQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPM--DGTYGPP--- 1380 P Q Q + + GN FS G +PF QN P+ D T P Sbjct: 831 PHVQAMQG--NSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLV 888 Query: 1381 -------AKRHEGEMYSVPYSTGQGQPQ-----------QQQLPPAQPQPASQQQAAQPS 1422 + H G + + +T +P+ QQ L +PA ++A QP Sbjct: 889 NLLQSDISAGHFG-VNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPP 947 Query: 1423 -PQQDVYN---------QYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNA 1472 P + N ++ N P + E+RP Q P Q V+ PP Sbjct: 948 LPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPL----QQMPPQL-MQHVAPPPQPPQ 1002 Query: 1473 QQNMP--PQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTD 1530 QQ P PQ P + + QQ Q + Q + + P V+ Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQ----QQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPR 1058 Query: 1531 EMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPM-TRPPPSNYQPPPSMQNHIPQVSSP- 1588 L+ D +++ P S VP M + P++ P P Q V++P Sbjct: 1059 GPLNPD-------------SQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPL 1105 Query: 1589 APLPRPM---ENRTSPSKSPFLHSGMKMQKAG---PPVPAS-HIAPAPVQPPMIRRDITF 1641 R M E+ +PS SP + +G P VP + P+ V P + +T Sbjct: 1106 GSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTG 1165 Query: 1642 P---PGSVEATQPVLKQR 1656 P P + ATQ Q+ Sbjct: 1166 PKPGPSPLSATQGATPQQ 1183 Score = 47.4 bits (111), Expect = 2e-04 Identities = 93/425 (21%), Positives = 131/425 (30%), Gaps = 69/425 (16%) Query: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPF 1245 G+ + N+ + + +K+ Q +NT D E ++ P PG Sbjct: 901 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPL------PGEQGI 954 Query: 1246 MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAP 1305 GP + + +R G V P Q P P P P P Sbjct: 955 NLDNSGPK--LPEFSNRPPGYPSQPVEQRPLQQMP---PQLMQHVAPPPQP--------P 1001 Query: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365 Q P P P P QQQQQQQ+ M QQ Sbjct: 1002 QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQ-------------------MMMMLMMQQD 1042 Query: 1366 QQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQ 1425 ++ + P+ PP + +P P L P S + P P Sbjct: 1043 PKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMP-- 1100 Query: 1426 DVYNQYGNAYPATATAATERRPAGGP---QNQFPFQFGRDRVSAPPGTNAQQNMPPQMMG 1482 V G+ + + P+ P P G + S P G N NMP ++ Sbjct: 1101 -VNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPN---NMPSHVV- 1155 Query: 1483 GPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHE 1542 + Q M G + Q G+ PQ P + + + + A + Sbjct: 1156 --------LPQNQLMMTGPKPGPSPLSATQ--GATPQQPPVNSLPSSHGHHFPNVAAPTQ 1205 Query: 1543 GSWPSHGTRQPPYGPSAPVPPMTRPP---PSNYQPPPSMQN------HIPQVSSPAPLPR 1593 S P R P P P P RPP PS P N PQ++ P P PR Sbjct: 1206 TSRPKTPNRASP-RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLP-PR 1263 Query: 1594 PMENR 1598 P NR Sbjct: 1264 PNLNR 1268 Score = 33.9 bits (76), Expect = 1.9 Identities = 76/410 (18%), Positives = 134/410 (32%), Gaps = 52/410 (12%) Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557 P+ Q S+ P + P ++ S H + + ++ P P S+P + Sbjct: 1532 PTLQDLSSSKEPSNSLNLPHSNELCSSLVHPEL------SEVSSNVAPSIPPVMSRPVSS 1585 Query: 558 SPYQQQQP---------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608 S P P ++ + AA P T + +S+ Sbjct: 1586 SSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQS 1645 Query: 609 GSQASSAPSMTSSK--GGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE-GALSPGVSTSG 665 +Q+++ P + + + S+PS++P P+ T G + P V+ G Sbjct: 1646 AAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAA-------PLTTNSGLMPPSVAVVG 1698 Query: 666 -ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724 + Q + + A P + +S P I+ P + S A+ Q S P + + V + Sbjct: 1699 PLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHP 1758 Query: 725 PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784 P + + P +N S+ Q + + PGS+ + R P G Sbjct: 1759 PVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKG 1818 Query: 785 ---------MGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPM 835 + + GS QYG G Q P G + Sbjct: 1819 KVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAP----------GLMGTE 1868 Query: 836 GAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCP 885 ++ + PP TL M + P GP A+ P + G P Sbjct: 1869 QLSTELDSKTPTPPAPTL-------LKMTSSPVGPGTASAGPSLPGGALP 1911 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 100 bits (250), Expect = 1e-20 Identities = 196/917 (21%), Positives = 299/917 (32%), Gaps = 137/917 (14%) Query: 111 PALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPP---PAYGFGQPYGRSPSAVAAAAAA 167 PAL+ + P + G+ A P A PP P G P SP AA Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968 Query: 168 VFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAP 227 GG +P S G P A P P+ + P+ P P P Sbjct: 969 TPPSPKGGPATP------SPKGAPTPPAATP---------PSPKGGPATPSPKGAPTP-P 1012 Query: 228 AYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTP 287 A SP+G +P + S PP ++ S S ++ + G P+ P Sbjct: 1013 AVTPPSPKG-SPAATPFPKGASTPPAATPPSPKGSPAATPLPK------GAPTTPAATLP 1065 Query: 288 QPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAA 347 P P L +P+ P G P GA PA A Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGG-PATPSPKGAPMPPA-------------ATPP 1111 Query: 348 AASGGAQQRSHH-APMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGG--TNPYSQQ 404 + GG H AP +P ++ + TP P P P GG T P Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP---P 1168 Query: 405 QGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQ 464 +G P+ P P + +P+ P T S GGL+ P + P+ Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA-----TPSPKGAPT---- 1219 Query: 465 QGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPS- 523 TP SP P P TP A P + + PP + PP + PS Sbjct: 1220 ---TPAATPPSPKGGLATPSPKGAPT--TPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274 Query: 524 -----QPPHQQSPAPYPSQQSTTQQHPQSQPPY---SQPQAQSPYQQQQPQQPAPSTLSQ 575 PPH+ +P P + + P + PP + P A P + P P P Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334 Query: 576 QAAY--PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQ 633 A P P+ + + P S++ + P+ T S G M Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG-----PTPPAATPSHKGGPAMTPPSP 1389 Query: 634 SRPSSLPDLSGSIDD---LPMGTEGALSPGVSTSGISS-SQGEQSNPAQSPFSPHTSPHL 689 R ++P G +P+ + A + V+ G ++ S+G+ + PA +P S +P Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP-- 1447 Query: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD 749 + +P G PA+ + S+ P PA P + P PP+ + + + Sbjct: 1448 -----ATSAPKGGPATPS-SKGDPTLPAVTPPS--PKEPPAPKQVATSSSPKKAPATPAP 1499 Query: 750 RGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGY 809 G +P P + S R P I + + + P+ P Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDP----IAPTATLLSKKTPATLAPKEALIPPAMTV 1555 Query: 810 PRQPNYNALPNANY----PSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGN 865 P A+P PS+ A P G P P L P ++ S Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASS-PPAVTPSTYKGAPS--PKELLIPPAVTSPSPKE 1612 Query: 866 RPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMG 925 P P + P+ G P G T + V +S+++ P Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKG--------TPTSPPVTPSSLKDSPT------------ 1652 Query: 926 TGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKA 985 +P MG T+ S G+ A L +V + PA + Sbjct: 1653 ----------------SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696 Query: 986 DGTPKTESKSKKSSSST 1002 + ++KKSS+++ Sbjct: 1697 TAPTRKGPQTKKSSATS 1713 Score = 99.4 bits (246), Expect = 4e-20 Identities = 184/832 (22%), Positives = 268/832 (32%), Gaps = 162/832 (19%) Query: 7 PAAASSLGNPPPP---PPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAV 63 PA S G P PP PPS G AA AA +G Sbjct: 1000 PATPSPKGAPTPPAVTPPSP-----------KGSPAATPFPKGASTPPAATPPSPKGSPA 1048 Query: 64 GPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGG 123 P P G A GG S G P + GP PP Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108 Query: 124 GGGGSSDGVGAPPHSAA----AALPP-PAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQS 178 G+ PPH A AA PP P G P P AA GG + Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP---PPKGAPTTPAATPPSPKGGLAT 1165 Query: 179 PGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGG- 237 P G P A P P+ + P PA SP+GG Sbjct: 1166 P------PPKGAPTTPAATPPSPKGGLATPSPKG----------APTTPAATPPSPKGGL 1209 Query: 238 -TPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTL 295 TP A + PPS ++ S A A PS GG TP P PT Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP---PSPKGGPATPPPKGAPT- 1265 Query: 296 NQLLTSPSSARG------YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAA 349 +P S +G ++G P P G GPA + GA AA + Sbjct: 1266 -PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG---GPATSPPK--GAPTPPAATPPS 1319 Query: 350 SGGAQQRSHHAPMSPGSSGGGGQPLARTPQP--------SSPMDQMGKMRPQPYGGTNPY 401 G+ P +P G P P P ++P + G P G P Sbjct: 1320 PKGS-------PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372 Query: 402 ----SQQQGP---PSGPQQGHGYPGQ----------PYGSQTPQRYPMTMQGRAQSAMGG 444 S + GP P P++G P P + P+T +G A + G Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432 Query: 445 LSYTQQIPPYGQQGPSGYGQQG--QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502 L+ P ++ P+ +G TP ++ P PP ++PP+ Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPS-SKGDPTLPAVTPPSPKEPPA----------- 1480 Query: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562 P Q+ +S P + P +P P+ + P+ P +P + Sbjct: 1481 -----PKQVATSS-----SPKKAPATPAPMGAPTLPAVIPSSPKEVPA-------TPSSR 1523 Query: 563 QQPQQPAPSTLSQQAAY---PQPQSQQSQQTAYSQQR---FPPPQELSQDSFGSQASSAP 616 + P P + LS++ P+ T S ++ P P+E +ASS P Sbjct: 1524 RDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583 Query: 617 SMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNP 676 ++T S + P E + P V++ S + + P Sbjct: 1584 AVTPS-----------------------TYKGAPSPKELLIPPAVTSP---SPKEAPTPP 1617 Query: 677 AQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMP--------PRP 728 A +P SP P P +G SP +P+S+ S + P S G +P + Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677 Query: 729 PSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780 P+ + ++ P+ + I ++ PQ + S+ P P +G + Sbjct: 1678 PTALKEVLVAPAPESTPII--TAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727 Score = 97.8 bits (242), Expect = 1e-19 Identities = 186/839 (22%), Positives = 265/839 (31%), Gaps = 165/839 (19%) Query: 224 PPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283 PP+P A +P TP S G PP + + S + F ++ G Sbjct: 858 PPSPKGA-PTPSAVTPLS----PKGVTLPPKETPTPSVVNLPFPKE-------------G 899 Query: 284 GGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGG--------AGKGPADMASQ 335 TP P P L+ +SP AR G S P+ + KG S Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959 Query: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPY 395 W AA + GG P +P G P A P P G P P Sbjct: 960 KWAPTPPAATPPSPKGG--------PATPSPKGAPTPPAATPPSPKG-----GPATPSPK 1006 Query: 396 GGTNPYSQQQGPPSGPQQGHGYP---------------GQPYGSQTPQRYPMTMQGRAQS 440 G P + P G +P G P + P+ P T S Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066 Query: 441 AMGGLSYTQ---------QIPPYGQQGPSGYGQQG--QTPYYNQQSPHPQQQQPPYSQQP 489 GG + PP + GP+ +G P SP PP+ P Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126 Query: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549 TP A P + + PP + P + PS P P P TT P + P Sbjct: 1127 T--TPAATPPSPKGGLATPPPKGAPTTPAATPPS--PKGGLATPPPKGAPTT---PAATP 1179 Query: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609 P + +P + P PA + S + P + + T + P + G Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239 Query: 610 SQASSAPSMTSSKGGQEDMNLSLQSRPSSL--PDLSGSIDDLPMGTEGALSPGVSTS--- 664 + + A + S KGG P + P L G + P +GA +P V T Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH--KGAPNPAVVTPPSP 1297 Query: 665 ----GISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS-------PSPVGSP---ASVAQSR 710 S +G + PA +P SP SP P +G PSP G+P A+ S+ Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357 Query: 711 SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSA 770 GP +P++ G P PS + M P + R P +P A Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK-----------RGPAIPSPKGDPTSPA 1406 Query: 771 LSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAG 830 + P P + G+ P G P P +L A SA G Sbjct: 1407 VIPLSPKKAP------ATPVTREGAATPSKGDLTPPAVTPV-----SLKKAPATSAPKGG 1455 Query: 831 GINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPP---- 886 P G P +P PP P P QV + P Sbjct: 1456 PATPSSKG-----DPTLP--AVTPPS-------------PKEPPAPKQVATSSSPKKAPA 1495 Query: 887 -PGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQG 945 P M T + S P P+ + + T A +++ + Sbjct: 1496 TPAPMGAPTLPAVIP------SSPKEVPATPSSRRDPIAPT-----------ATLLSKKT 1538 Query: 946 PPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTT 1004 P T+A A + P M + K TPA +A TP ++ S + + +T Sbjct: 1539 P-----ATLAPKEALI---PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589 Score = 97.1 bits (240), Expect = 2e-19 Identities = 182/828 (21%), Positives = 275/828 (33%), Gaps = 117/828 (14%) Query: 225 PAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284 P+P SP+ P + +A P + S+ S +SF + + G S A Sbjct: 794 PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853 Query: 285 GTPQPTA---TPTLNQLLTSPSSARGYQGYPGGDYSGG------PQDGGAGKGP--ADMA 333 +P P + PT + + +P S +G P + P++G A P A Sbjct: 854 HSPTPPSPKGAPTPSAV--TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911 Query: 334 SQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSS-PMDQMGKMRP 392 S + A A A G P SP G P A P P P K P Sbjct: 912 SMTSSSPKKARATPAPKG--------IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963 Query: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY--PMTMQGRAQSAMGGLSYTQQ 450 P T P +G P+ P P G+ TP P G A + G Sbjct: 964 TPPAATPP--SPKGGPATPS--------PKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013 Query: 451 IPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510 + P PS G TP+ P+ P + PPS P P+ P+ P Sbjct: 1014 VTP-----PSPKGSPAATPF-------PKGASTPPAATPPS--PKGSPAATPLPKGAPTT 1059 Query: 511 LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570 ++ P P+ P + +P P P + PP + +P + P PA Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTP-----------PAATPPSPKGGPATPSPKGAPMPPAA 1108 Query: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630 + S + P + + T + P + G+ + A + S KGG Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT--- 1165 Query: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSP-GVSTSGISSSQGEQS-----NPAQSPFSPH 684 P P + P G SP G T+ ++ + +P +P +P Sbjct: 1166 ---PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222 Query: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744 +P P +PSP G+P + A + P A P + P PP+ S+ + Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL------KG 1276 Query: 745 SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG--PQGGQ 802 +A NP + SP+ G A SP P G T + + GS G P G Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAP--TPPAATPPSPKGSPGTPPPKGA 1332 Query: 803 YGPQGGYPRQPNYNALPNANYPSA-------GMAGGINPMGAGGQMHGQPGIPPYG---- 851 P P P A PS+ G P A G P + P Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392 Query: 852 -TLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQN 910 +P + S P P A P G P G T V++ A + + Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT--S 1450 Query: 911 RPPGYPNMNQGGMMGTGPPYGQGINSMAGMI--NPQGPPYSMGGTMANNSAGMAASPEMM 968 P G G P +G ++ + +P+ PP +++ A+P M Sbjct: 1451 APKG----------GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500 Query: 969 GL--------GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKI 1008 G K PAT + + P SKK+ ++ E + Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548 Score = 94.0 bits (232), Expect = 2e-18 Identities = 150/685 (21%), Positives = 212/685 (30%), Gaps = 112/685 (16%) Query: 96 AEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYG 155 A P K + P+ A PP GG ++ P AA P P G P Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK---GGPAT 979 Query: 156 RSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSY 215 SP AA GG +P Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGA------------------------------- 1008 Query: 216 YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMG 275 P A PP+P G+P + S PP ++ S S ++ + Sbjct: 1009 -PTPPAVTPPSPK--------GSPAATPFPKGASTPPAATPPSPKGSPAATPLPK----- 1054 Query: 276 GGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQ 335 G P+ P P P L +P+ P G GPA + + Sbjct: 1055 -GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG-------------GPATPSPK 1100 Query: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPY 395 AA + G A AP +P ++ + TP P P P Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160 Query: 396 GG--TNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453 GG T P +G P+ P P + +P+ P T S GGL+ P Sbjct: 1161 GGLATPP---PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA-----TP 1212 Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513 + P+ TP SP P S + TP A P + + PP + Sbjct: 1213 SPKGAPT-------TPAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGPATPPPKGA 1263 Query: 514 SQPPYSQQPS------QPPHQQSPAPYPSQQSTTQQHPQSQPPY---SQPQAQSPYQQQQ 564 PP + PS PPH+ +P P + + P + PP + P A P + Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323 Query: 565 PQQPAPSTLSQQAAYPQPQ------------SQQSQQTAYSQQRFPPPQELSQDSFGSQA 612 P P P A P S + T S + P P + G A Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383 Query: 613 SSAPS-----MTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGIS 667 + PS S G + P P + + ++G L+P T Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443 Query: 668 SSQGEQSNPAQSPFSPHT--SPHLPGIRGPSPSPVGSPASVAQSRS---GPLSPAAVPGN 722 S P P +P + P LP + PSP +P VA S S P +PA + Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503 Query: 723 QMPPRPPSGQSDSIMHPSMNQSSIA 747 +P PS + PS + IA Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIA 1528 Score = 71.6 bits (174), Expect = 8e-12 Identities = 143/583 (24%), Positives = 185/583 (31%), Gaps = 142/583 (24%) Query: 1113 PPPDIFAAADSKK---SQPKIQPPSPAGSGSMQGPQ---TPQSTSSSMAEGGDLKP-PTP 1165 P P A+ S K + P PPSP G + P+ TP + + +GG P P Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG 984 Query: 1166 ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMS 1225 A TP + PP P G +T + + TP PS S Sbjct: 985 APTPPAATPPSP---------------KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP 1029 Query: 1226 YEPNKDPYG---SMRKAPGSDPFMSSGQ--------GPNGG------MGDPYSRAAGPGL 1268 + P S + +P + P P GG G P AA P Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP- 1088 Query: 1269 GNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMST----GAPQ-PNLMPSNPDSGMYSPSR 1323 + GP P G P T P P+G ++T GAP P P +P G+ +P Sbjct: 1089 -SPKGGPATPSPKGAPMPPAATPPS--PKGGLATPPHKGAPTTPAATPPSPKGGLATP-- 1143 Query: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKR 1383 PP+ TP+ +P PS P G PP K Sbjct: 1144 -PPK----------------GAPTTPAATP-PS---------------PKGGLATPPPKG 1170 Query: 1384 HEGEMYSVPYSTGQG----QPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATA 1439 + P S G P+ PA P+ + A PSP+ T Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG----------APTT 1220 Query: 1440 TAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQ 1499 AAT P GG P + + P T PP GGP + A Sbjct: 1221 PAATPPSPKGGLATPSP----KGAPTTPAAT------PPSPKGGPATPPPKGAP------ 1264 Query: 1500 GRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHG-TRQPPYGPS 1558 T A P+ G T A P G PP G Sbjct: 1265 --------------TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG-- 1308 Query: 1559 APVPPMTRPPP---SNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSG--MKM 1613 AP PP PP S PPP P V+ P+P P T P+ +P G Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP----TLPATTPSSKGGPTTPS 1364 Query: 1614 QKAGPPVPA---SHIAPAPVQPPMIRRDITFPPGSVEATQPVL 1653 K GP PA SH + PP +R P + T P + Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407 Score = 66.6 bits (161), Expect = 3e-10 Identities = 134/568 (23%), Positives = 184/568 (32%), Gaps = 74/568 (13%) Query: 1113 PPPDIFAAADSKK---SQPKIQPPSPAGSGSM----QGPQTPQSTSSSMAEGGDLKPPTP 1165 P P A S K + P + PPSP GS + +G TP + + +G P P Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053 Query: 1166 ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDST--FQKRNSMTPNPG---YQPSMNTSDM 1220 P + LP + +T K TP+P P+ Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113 Query: 1221 MGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGL--GNVAMGPRQH 1278 G ++ P+K G+ + P G G P + AA P G +A P Sbjct: 1114 KGGLATPPHK---GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP--- 1167 Query: 1279 YPYGGPYDRVRTEPGIGPEGNMSTGAPQ-----PNLMPSNPDSGMYSPSRYPPQQQQQQQ 1333 P G P T P P+G ++T +P+ P P +P G+ +PS P Sbjct: 1168 -PKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGLATPS--PKGAPTTPA 1222 Query: 1334 QRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPY 1393 S +T +P G+P T P G PP K + P Sbjct: 1223 ATPPSPKGGLATP-SPKGAPTTPAATP---------PSPKGGPATPPPKGAPTPPAATPP 1272 Query: 1394 ST--GQGQPQQQQLP-PAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGG 1450 S G P + P PA P S + SP + T AAT P G Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA---------PTPPAATPPSPKGS 1323 Query: 1451 PQNQFPFQFGRDRVSAPPGTNAQQNMP---PQMMGGPIQASAEVAQQGTM----WQGRND 1503 P P PP +P P GGP S++ +G Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383 Query: 1504 MTYNYANRQSTGSAPQG-PAYHGVNRTDEMLHTDQRANHEGS-WPSHGTRQPPYGP--SA 1559 MT R +P+G P V EG+ PS G PP S Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443 Query: 1560 PVPPMTRPPPSNYQPPPSMQNH-IPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGP 1618 P T P P S + +P V+ P+P P + + S SP K P Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP---------KKAP 1494 Query: 1619 PVPASHIAPA-PVQPPMIRRDITFPPGS 1645 PA AP P P +++ P S Sbjct: 1495 ATPAPMGAPTLPAVIPSSPKEVPATPSS 1522 Score = 61.2 bits (147), Expect = 1e-08 Identities = 129/581 (22%), Positives = 190/581 (32%), Gaps = 118/581 (20%) Query: 475 SPHPQQQQPPYSQQPPS-QTPHAQPSYQQQPQSQPPQLQ--------SSQPPYSQQPSQP 525 +P PQ P + + + P + PS P PP + S+ P + P + Sbjct: 711 APSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKEC 770 Query: 526 PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQ 585 P + S A + T + P P S PQ P T A P Sbjct: 771 PTEDSGASATASSKGTLTYLADSP---SPLGVSV----SPQTKRPPTKKGSAGPDTPIGN 823 Query: 586 QSQQTAYSQQRFPPPQELS-QDSFGSQASS-APSMTSSKGGQEDMNLS-LQSRPSSLPDL 642 S + + F P LS Q S S A++ +P+ S KG ++ L + +LP Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPK 883 Query: 643 ---SGSIDDLPMGTEGALSPGVSTS--------------------GISSS---QGEQSNP 676 + S+ +LP EG +P + GI +S +G + P Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943 Query: 677 AQSPFSPHTSPHLPGIR---------------GPS-PSPVGSPASVAQSRSGPLSPAAVP 720 A +P SP P P + GP+ PSP G+P A + P A P Sbjct: 944 AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003 Query: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQ 780 + P PP ++ PS S A P+ +S P A +P P G Sbjct: 1004 SPKGAPTPP-----AVTPPSPKGSPAA---------TPFPKGASTPP--AATPPSPKGSP 1047 Query: 781 IHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPN--ANYPSAGMAGGINPMGAG 838 T + + + P P+GG P P+ P A P + G P G Sbjct: 1048 AATPLPKGAPTTPAATLP-----SPKGG-PATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101 Query: 839 GQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETA 898 M PP T P + A+ ++ A PP G+ PP Sbjct: 1102 APM------PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP----------- 1144 Query: 899 VAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMA---------GMINPQGPPYS 949 P P +GG + T PP G A +P+G P + Sbjct: 1145 ------PKGAPTTPAATPPSPKGG-LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197 Query: 950 MGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPK 990 T + G+A TP + A +PK Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238 Score = 59.3 bits (142), Expect = 4e-08 Identities = 116/557 (20%), Positives = 173/557 (31%), Gaps = 55/557 (9%) Query: 1128 PKIQPPSPAGSGSMQ----GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSN 1183 P PPSP G + P TP +T S G PP A T + PP P + Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165 Query: 1184 SVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSD 1243 + K TP+P P+ + P G+ + Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225 Query: 1244 PFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMST- 1302 P G G P + AA P + GP P G P T P + +G ++T Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPP--SPKGGPATPPPKGAPTPPAATPPSL--KGGLATP 1281 Query: 1303 ---GAPQPNLM-PSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQ 1358 GAP P ++ P +P G P+ PP+ P G+P P Sbjct: 1282 PHKGAPNPAVVTPPSPKGG---PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338 Query: 1359 TTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQA 1418 T + + G P E + P +T + PA P+ ++ Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-----PSHKGGPAMTPPSPKRGP 1393 Query: 1419 AQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPP 1478 A PSP+ D + PA + ++ PA + + ++ P T P Sbjct: 1394 AIPSPKGDPTS------PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447 Query: 1479 QMM---GGPIQASAE----VAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDE 1531 GGP S++ + A S AP PA G Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507 Query: 1532 MLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRP----------PPSNYQPPPSMQNH 1581 ++ + + + PS +R+ P P+A + P PP+ P P Sbjct: 1508 VIPSSPK--EVPATPS--SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563 Query: 1582 IPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQK-------AGPPVPASHIAPAPVQPPM 1634 IP P E + P+ +P + G K P P P V PP Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623 Query: 1635 IRRDITFPPGSVEATQP 1651 + P T P Sbjct: 1624 PEKGPATPAPKGTPTSP 1640 Score = 56.2 bits (134), Expect = 4e-07 Identities = 124/553 (22%), Positives = 188/553 (33%), Gaps = 69/553 (12%) Query: 1128 PKIQPPSPAGSGSMQGPQ----TPQSTSSSMAEGGDLKPPTPASTPHSQIPPLP--GMSR 1181 P PPSP G + P+ TP +T S G PP A T + PP P G++ Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188 Query: 1182 SNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG 1241 + G + K TP+P P+ + P G+ Sbjct: 1189 PSPKGAPTT--PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246 Query: 1242 SDPFMSSGQGPNGGMGDPYSRAAGPGL--GNVAMGPRQHYPYGGPYDRVRTEPGIGPEGN 1299 + P G G P AA P G +A P + G P V T P P+G Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK----GAPNPAVVTPPS--PKGG 1300 Query: 1300 MSTGAPQ--PNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS-GSPFPS 1356 +T P+ P + P S SP PP+ S +GTP+ + PS Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP-----SPKGTPTLPATTPS 1355 Query: 1357 QQ---TTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQ-- 1411 + TT ++ G PA + +G P + P P+ Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415 Query: 1412 ---PASQQQAAQPSPQQDVYNQYGNAYPATATAATERR------PAGGPQNQFPFQFGRD 1462 P +++ AA PS G+ P T + ++ P GGP P G Sbjct: 1416 PATPVTREGAATPSK--------GDLTPPAVTPVSLKKAPATSAPKGGPAT--PSSKGDP 1465 Query: 1463 RVSAPPGTNAQQNMPPQMMG---GPIQASAEVAQQG--TMWQGRNDMTYNYANRQSTGSA 1517 + A + ++ P+ + P +A A A G T+ S+ Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525 Query: 1518 PQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPS---APVPPMTR----PP-- 1568 P P +++ + A + ++ P P+ AP P ++ PP Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585 Query: 1569 -PSNYQPPPSMQNHI--PQVSSPAPLPRPME---NRTSPSKSPFLHSGMKMQKAGPPVPA 1622 PS Y+ PS + + P V+SP+P P SP K P K PPV Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP-ATPAPKGTPTSPPVTP 1644 Query: 1623 SHIAPAPVQPPMI 1635 S + +P P + Sbjct: 1645 SSLKDSPTSPASV 1657 Score = 33.1 bits (74), Expect = 3.2 Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 40/215 (18%) Query: 508 PPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQ 567 P + + P Q+ QP + + P S S T QP + P SP PQQ Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTA--ALGQPGPTLPPPCSP----APQQ 55 Query: 568 PAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQED 627 S +Q + +P P + A + P PQ S ++ P T+ + Sbjct: 56 CPLSAANQASPFPSPST-----IASTPLEVPFPQ-------SSSGTALPLGTAPEA---- 99 Query: 628 MNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTS--GISSSQGEQSNPAQSPFSPHT 685 P+ LP+L G + SP ++ + G SS + A +P S Sbjct: 100 --------PTFLPNLIG--PPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQK 149 Query: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVP 720 S P P+ + SP SVA + SG + + P Sbjct: 150 SSAFP------PNLLTSPPSVAVAESGSVITLSAP 178 Score = 32.7 bits (73), Expect = 4.2 Identities = 63/302 (20%), Positives = 103/302 (34%), Gaps = 38/302 (12%) Query: 1349 PSG-SPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRH---EGEMYSVPYSTGQGQPQQQQ 1404 P+G +P ++ T+ Y + ++GT K H EG + ++P P + Sbjct: 655 PAGVAPTTAKGTSTYTTTASPF---LEGTVSLAPKNHPVKEGTLTTLPLV-----PTASE 706 Query: 1405 LPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRV 1464 P P P Q P + + + P+ + PAG P Sbjct: 707 NCPVAPSP---QNTCAPLATLVLAPEIPKSVPSPSLP-----PAGTPPGTKKVDGISHTS 758 Query: 1465 SAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMT------YNYANRQSTGSAP 1518 + P ++ + P + G ASA + +GT+ + + R T Sbjct: 759 ALAPVASSPKECPTEDSG----ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS 814 Query: 1519 QGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTR--PPPSNYQPPP 1576 GP N + + + E S G++ P +P PP + P PS P Sbjct: 815 AGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLS 874 Query: 1577 SMQNHIPQVSSPAP----LPRPMENRTSPS--KSPFLHSGMKMQKAGPPVPASHIAPAPV 1630 +P +P P LP P E +P+ ++P L K PA PA Sbjct: 875 PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934 Query: 1631 QP 1632 P Sbjct: 935 SP 936 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 100 bits (249), Expect = 2e-20 Identities = 233/985 (23%), Positives = 308/985 (31%), Gaps = 171/985 (17%) Query: 37 GEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGG--GGAGSGGGP 94 GE A A G E VG P P G DG+ G G G AG G P Sbjct: 199 GEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFP 258 Query: 95 GAEPDLKN---SNGNAGPR-----------PALNNNLTEPPGGGGGGSSDGVGAPPHSAA 140 GA P K + GNAGP P L+ + P G G + GA Sbjct: 259 GA-PGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGA------ 311 Query: 141 AALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEP-YAGPQ 199 A LP A G P R AA A + G+ P + +SG G EP AGPQ Sbjct: 312 AGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG--EPGSAGPQ 369 Query: 200 QNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASA 259 PP P S G +G A +AG PP S Sbjct: 370 G-----------------------PPGP----SGEEGKRGPNGEAGSAGPPGPPGLRGSP 402 Query: 260 SSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGG 319 S A R G MG G A G P+ RG P GD +G Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASG-----------------PAGVRG----PNGD-AGR 440 Query: 320 PQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP-LARTP 378 P + G GP + A G R P G +G G+P P Sbjct: 441 PGEPGL-MGPRGLPGSPGNIGPAGKEGPVGLPGIDGR----PGPIGPAGARGEPGNIGFP 495 Query: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438 P P GK + + G + +G P GP +G G P G Q Q G+ Sbjct: 496 GPKGPTGDPGKNGDKGHAG---LAGARGAP-GPDGNNGAQGPP-GPQGVQ------GGKG 544 Query: 439 QSAMGGLSYTQQIPPYGQQGPSG-YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQ 497 + G Q +P G GP+G G+ G+ + + P P + PP ++ A Sbjct: 545 EQGPPGPPGFQGLP--GPSGPAGEVGKPGERGLHGEFG-LPGPAGPRGERGPPGESGAAG 601 Query: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP---PYSQP 554 P + P S+ PS PP P S P P + Sbjct: 602 P---------------TGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERG 646 Query: 555 QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS 614 A P + + +P L + P + A P P + D + A+ Sbjct: 647 AAGIPGGKGEKGEPG---LRGEIGNPGRDGARGAPGAVGA---PGPAGATGDRGEAGAAG 700 Query: 615 APSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALSPGVSTSGISSSQGEQ 673 +G + + P+ +G+ G GA P +G+ G Sbjct: 701 PAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGP-KGENGVVGPTGPV 759 Query: 674 SNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQS 733 A P P+ P G RG P + A R+GP P+ + G PP P Sbjct: 760 G--AAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAG--K 815 Query: 734 DSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSM 793 + + P +Q + + P PG A + PSG Sbjct: 816 EGLRGPRGDQGPVGRTGEVGAVGP---------PGFA-GEKGPSG-------------EA 852 Query: 794 GSYGPQGGQYGPQG--------GYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP 845 G+ GP G GPQG G P LP AG G P+G G Sbjct: 853 GTAGPPGTP-GPQGLLGAPGILGLPGSRGERGLPGV----AGAVGEPGPLGIAG------ 901 Query: 846 GIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVG-SGMCPPPGGMNRKTQETAVAMHVA 904 PP PPG + + P P G G PG + + A Sbjct: 902 --PPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA 959 Query: 905 ANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAAS 964 A + P P G TGP G G P GP G G Sbjct: 960 AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGL 1019 Query: 965 PEMMGLGDVKLTPATKMNNKADGTP 989 P + G ++ P ++ G P Sbjct: 1020 PGLKGHNGLQGLPGIAGHHGDQGAP 1044 Score = 99.0 bits (245), Expect = 5e-20 Identities = 244/1073 (22%), Positives = 328/1073 (30%), Gaps = 182/1073 (16%) Query: 39 AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGG--GGGGGAGSGGGPGA 96 A + E K AG GPP P G++ +DG G G G G GG A Sbjct: 20 ATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAA 79 Query: 97 EPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAP---PHSAAAALPPPAYGFGQP 153 + D K GP + PPG G G P P P A G P Sbjct: 80 QYDGKGVGLGPGPMGLMGPR--GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGP 137 Query: 154 YGRS-----PSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFP 208 G++ P G + PG L G G+ + G G P Sbjct: 138 PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLP--GFKGIRGHNGLDGLKGQPGAP 195 Query: 209 NHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPG-------SGAAAAAGSKPPPSSSASA 259 + P + P A L RG G PG G+ G P S+ Sbjct: 196 GVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPP 255 Query: 260 SSSSSSFAQQRFGAMGGGGPSAAGG-----------GTPQPTATPTLNQLLTSPSSARGY 308 + + GA+G GP+ G G P P N L + A+G Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGL----TGAKGA 311 Query: 309 QGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSG 368 G PG +G P GP + A A A G S G SG Sbjct: 312 AGLPG--VAGAP----GLPGPRGIPGPVGAAGATGARGLVGEPGPAG-------SKGESG 358 Query: 369 GGGQPLARTPQ-PSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427 G+P + PQ P P + GK P G+ GPP P G G P P Sbjct: 359 NKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS------AGPPGPP----GLRGSPGSRGLP 408 Query: 428 QRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQ 487 GRA MG P G +GP+ G G+ P P Sbjct: 409 -----GADGRA-GVMGPPGSRGASGPAGVRGPN--GDAGRPGEPGLMGPRGLPGSPGNIG 460 Query: 488 QPPSQTPHAQPSYQQQPQSQPPQLQSSQP-----PYSQQPSQPPHQQSP----------- 531 + P P +P P +P P + P+ P + Sbjct: 461 PAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARG 520 Query: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ-QPAPSTLSQQAAYPQPQSQQSQ-- 588 AP P + Q P Q Q P Q P PS + + P + + Sbjct: 521 APGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFG 580 Query: 589 ---QTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQED-------MNLSLQSRPSS 638 +R PP + + G S PS G + + + S PS Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640 Query: 639 LPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPS 698 LP G+ +P G PG+ +GE NP + +P G GP+ + Sbjct: 641 LPGERGAA-GIPGGKGEKGEPGL--------RGEIGNPGRD--GARGAPGAVGAPGPAGA 689 Query: 699 PVGSPASVAQSRSGPLSPAAVPG--NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRN 756 + A +GP P PG ++ P P+G + + Q +RG Sbjct: 690 TGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA--GAAGQPGAKGERGAKGPK 747 Query: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG--------GQYGPQG- 807 + P A P P+G G S G GP G G+ GP G Sbjct: 748 GENGVVGPTGPVGAAGPAGPNGPPGPAG-------SRGDGGPPGMTGFPGAAGRTGPPGP 800 Query: 808 ----GYPRQPNYNALPNANYP--------SAGMAGGINPMGAGGQ--------MHGQPGI 847 G P P P G G + P G G+ G PG Sbjct: 801 SGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGT 860 Query: 848 P-PYGTL-PPGRMS-HASMGNRPYGPNMANMPPQVGS-GMCPPPGGMNRKTQETAVAMHV 903 P P G L PG + S G R P +A + G G+ PPG + ++ Sbjct: 861 PGPQGLLGAPGILGLPGSRGERGL-PGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNG 919 Query: 904 A-------ANSIQNRPP------------GYP-NMNQGGMMGTGPPYG-------QGINS 936 A N + PP GYP N+ G G P+G G Sbjct: 920 APGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRG 979 Query: 937 MAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTP 989 G P GP ++G + G+ G + P K +N G P Sbjct: 980 ETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLP 1032 Score = 90.5 bits (223), Expect = 2e-17 Identities = 209/858 (24%), Positives = 281/858 (32%), Gaps = 130/858 (15%) Query: 35 AGGEAAAAAAAERGEM--KAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGG 92 AG A E G K +G + E + GP P G ++G G G AGS G Sbjct: 336 AGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKR----GPNGEAGSAG 391 Query: 93 GPGAEPDLKNSNGNAG-PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG 151 PG P L+ S G+ G P + PPG G GV P A P G Sbjct: 392 PPGP-PGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMG-- 448 Query: 152 QPYGR--SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPN 209 P G SP + A + G PG+ G G + P AG + + GFP Sbjct: 449 -PRGLPGSPGNIGPAG------KEGPVGLPGI----DGRPGPIGP-AGARGEPGNIGFPG 496 Query: 210 HQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQ 269 + + P ++ A L+ RG G A G PP Sbjct: 497 PKGPTGDPGKNGDKGHA---GLAGARGAPGPDGNNGAQG---PPGPQGVQGGKGEQGPPG 550 Query: 270 RFGAMGGGGPSAAGGGTPQPTATPTLNQL-LTSPSSARGYQGYPGGDYSGGPQDGGAGKG 328 G G GPS G +P + L P+ RG +G PG + GP +G Sbjct: 551 PPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRG 610 Query: 329 PA-----DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLAR----TPQ 379 P+ D G A A + A PG G G+P R P Sbjct: 611 PSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG 670 Query: 380 PSSPMDQMGKM-RPQPYGGTNPYSQQQGP-PSGPQQGHGYPGQPYGSQTPQRYPMTMQGR 437 G + P P G T + P+GP G PG+ R Sbjct: 671 RDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGE----------------R 714 Query: 438 AQSAMGGLSYTQQIPPYGQQGPSGY-GQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496 + G P G GP+G GQ G + P + P A Sbjct: 715 GEVGPAG--------PNGFAGPAGAAGQPGAKGERGAKGPKGENGVVG----PTGPVGAA 762 Query: 497 QPSYQQQPQSQPPQLQSSQPP-YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQ 555 P+ P PP + P P P S P P + Sbjct: 763 GPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGP-----SGISGPPGPPGPAGKEG 817 Query: 556 AQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSA 615 + P + Q P T A P + + + + PP Q G A Sbjct: 818 LRGP---RGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLG-----A 869 Query: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDL-PMGTEGALS----PG-VSTSGISSS 669 P + G + + L P ++G++ + P+G G PG V + G++ + Sbjct: 870 PGILGLPGSRGERGL---------PGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGA 920 Query: 670 QGE---QSNPAQS-PFSPHTSPHLPGIRG--PSPSPVGSPASVAQSRSGPLSPAAVPGN- 722 GE NP P P G RG + PVG A+ A GP+ PA GN Sbjct: 921 PGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG--AAGAPGPHGPVGPAGKHGNR 978 Query: 723 -QMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI 781 + P P G + ++ RG PQ + +PG PR G + Sbjct: 979 GETGPSGPVGPAGAV-----------GPRG--PSGPQGIRGDKGEPGEK-GPRGLPGLKG 1024 Query: 782 HTGMGSYQQNSMGSYGPQG--GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMG-AG 838 H G+ G +G QG G GP G PR P + P G G + P G G Sbjct: 1025 HNGLQGLP-GIAGHHGDQGAPGSVGPAG--PRGPAGPSGPAGKDGRTGHPGTVGPAGIRG 1081 Query: 839 GQMHGQPGIPPYGTLPPG 856 Q H P PP PPG Sbjct: 1082 PQGHQGPAGPPGPPGPPG 1099 Score = 82.0 bits (201), Expect = 6e-15 Identities = 192/789 (24%), Positives = 243/789 (30%), Gaps = 116/789 (14%) Query: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66 P +A G PP P E K+ + AG G + G + +GPP Sbjct: 363 PGSAGPQG-PPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGS-RGLPGADGRAGVMGPP 420 Query: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPG--AEPDLKNSNGNAGPRPALNNNLTEPPGGG 124 G G G G AG G PG L S GN GP E P G Sbjct: 421 GSRGASGPAGVR----GPNGDAGRPGEPGLMGPRGLPGSPGNIGPAG------KEGPVGL 470 Query: 125 GGGSSDGVGAPPHSAAAALPPPAYGFGQPYG----------RSPSAVAAAAAAVFHQ-QH 173 G DG P A A P GF P G + + +A A A + Sbjct: 471 PG--IDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNN 528 Query: 174 GGQQSPGLAALQSG-------GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPA 226 G Q PG +Q G G G + GP + + G P + + P Sbjct: 529 GAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGER-----GLHGEFGLPG 583 Query: 227 PAYALSSPRG--GTPG-SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAG 283 PA PRG G PG SGAA G S + GA+G GPS Sbjct: 584 PA----GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPS 639 Query: 284 G--GTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341 G G P P RG G PG D + G GPA A A Sbjct: 640 GLPGERGAAGIPGGKGEKGEP-GLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGA 698 Query: 342 AAAAAAAASGGAQ-QRSHHAPMSP----GSSGGGGQPLARTPQ-PSSPMDQMGKMRPQ-P 394 A A A G+ +R P P G +G GQP A+ + P + G + P P Sbjct: 699 AGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGP 758 Query: 395 YGGTNPYSQQQGPP--------SGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLS 446 G P + GPP GP G+PG +T P + G G Sbjct: 759 VGAAGP-AGPNGPPGPAGSRGDGGPPGMTGFPGA--AGRTGPPGPSGISG-PPGPPGPAG 814 Query: 447 YTQQIPPYGQQGPSG----YGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502 P G QGP G G G + ++ P + P Q P Sbjct: 815 KEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILG 874 Query: 503 QPQS--------------QPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQ 548 P S +P L + PP ++ P P + Sbjct: 875 LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDG 934 Query: 549 PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608 PP Q ++ P P A P P + + P Sbjct: 935 PPGRDGQPGHKGERGYPGNIGP---VGAAGAPGPHGPVGPAGKHGNRGETGPSG-PVGPA 990 Query: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS 668 G+ PS +G + D + P LP L G G +G GI+ Sbjct: 991 GAVGPRGPS--GPQGIRGDKGEPGEKGPRGLPGLKGH-----NGLQG-------LPGIAG 1036 Query: 669 SQGEQSNPAQ-SPFSPHTSPHLPGIRGPS-----PSPVGSPASV--AQSRSGPLSPAAVP 720 G+Q P P P G G P VG PA + Q GP P P Sbjct: 1037 HHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVG-PAGIRGPQGHQGPAGPPGPP 1095 Query: 721 GNQMPPRPP 729 G PP PP Sbjct: 1096 G---PPGPP 1101 Score = 69.7 bits (169), Expect = 3e-11 Identities = 131/511 (25%), Positives = 173/511 (33%), Gaps = 105/511 (20%) Query: 3 AQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPA 62 A+ AP A + P P + + E AG + ERGE+ A GPA Sbjct: 674 ARGAPGAVGA----PGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPA 729 Query: 63 VGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG 122 QP G + + GA+ G G G G GA G AGP N P G Sbjct: 730 GAAGQP-GAKGERGAK-GPKGENGVVGPTGPVGAA-------GPAGP-----NGPPGPAG 775 Query: 123 GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLA 182 G G G+ P +A PP G P P A G Q G Sbjct: 776 SRGDGGPPGMTGFPGAAGRTGPPGPSGISGP----PGPPGPAGKEGLRGPRGDQGPVG-- 829 Query: 183 ALQSGGGGGLEP--YAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240 ++G G + P +AG + S + G +A PP GTPG Sbjct: 830 --RTGEVGAVGPPGFAGEKGPSGEAG-------------TAGPP------------GTPG 862 Query: 241 -SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLL 299 G A G P S + A G +G GP A G P +P +N Sbjct: 863 PQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGA-RGPPGAVGSPGVN--- 918 Query: 300 TSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH 359 +P A G G PG D GP G P + + AA A G H Sbjct: 919 GAPGEA-GRDGNPGND---GPP--GRDGQPGHKGERGYPGNIGPVGAAGAPG------PH 966 Query: 360 APMSP-GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYP 418 P+ P G G G+ PS P+ G + P+ PSGPQ G Sbjct: 967 GPVGPAGKHGNRGE-----TGPSGPVGPAGAVGPR-------------GPSGPQGIRGDK 1008 Query: 419 GQPYGSQTPQRYPMTMQGRAQSAMGGLS-------YTQQIPPYGQQGPSG----YGQQGQ 467 G+P G + P+ P + G++ + P G +GP+G G+ G+ Sbjct: 1009 GEP-GEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067 Query: 468 TPYYNQQSP----HPQQQQPPYSQQPPSQTP 494 T + P PQ Q P P P Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP 1098 Score = 55.8 bits (133), Expect = 5e-07 Identities = 94/390 (24%), Positives = 118/390 (30%), Gaps = 95/390 (24%) Query: 2 AAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGP 61 A + P S + PP PP AG E ++G + G+ E Sbjct: 792 AGRTGPPGPSGISGPPGPP------------GPAGKEGLRGPRGDQGPV----GRTGEVG 835 Query: 62 AVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPP 121 AVGPP G++ G G AG+ G P G GP+ L Sbjct: 836 AVGPPGFAGEK----------GPSGEAGTAGPP----------GTPGPQGLL-------- 867 Query: 122 GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGL 181 G+ +G P LP A G+P P +A G + PG Sbjct: 868 -----GAPGILGLPGSRGERGLPGVAGAVGEP---GPLGIAGPP--------GARGPPG- 910 Query: 182 AALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYP---PPAPAYALSSPRGGT 238 A+ S G G AG N + G P + YP P A P G Sbjct: 911 -AVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPV 969 Query: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG--------GTPQPT 290 +G G P A GA+G GPS G G P Sbjct: 970 GPAGKHGNRGETGPSGPVGPA------------GAVGPRGPSGPQGIRGDKGEPGEKGPR 1017 Query: 291 ATPTLN-----QLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345 P L Q L + G QG PG GP+ GPA + A Sbjct: 1018 GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPA 1077 Query: 346 AAAASGGAQQRS-----HHAPMSPGSSGGG 370 G Q + P PG SGGG Sbjct: 1078 GIRGPQGHQGPAGPPGPPGPPGPPGVSGGG 1107 Score = 36.2 bits (82), Expect = 0.38 Identities = 81/373 (21%), Positives = 119/373 (31%), Gaps = 39/373 (10%) Query: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFN 1192 P P G+ QGP PQ E G PP P P + + G+ F Sbjct: 522 PGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLP-GPSGPAGEVGKPGERGLHGEF- 579 Query: 1193 DGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252 G R P PG + + +G P G+ + PG + + GP Sbjct: 580 -GLPGPAGPRGERGP-PGESGAAGPTGPIGSRGPSGPPGPDGN-KGEPGVVGAVGTA-GP 635 Query: 1253 NGGMGDPYSRAAG--PGLGNVAMGPRQHYPYGGP-YDRVRTEPG-IGPEGNMSTGAPQPN 1308 +G G P R A PG P G P D R PG +G G + Sbjct: 636 SGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGE 695 Query: 1309 LMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQN 1368 + P +G P P ++ + + + G P + + Sbjct: 696 AGAAGP-AGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVG 754 Query: 1369 YKRPM--------DGTYGPPAKRHEG---EMYSVPYSTGQ-GQPQQQQL--PPAQPQPAS 1414 P+ +G GP R +G M P + G+ G P + PP P PA Sbjct: 755 PTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAG 814 Query: 1415 QQQAAQPSPQQDVYNQYGNAYPATATA-ATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQ 1473 ++ P Q + G A E+ P+ G + PPGT Sbjct: 815 KEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPS-----------GEAGTAGPPGTPGP 863 Query: 1474 QNM--PPQMMGGP 1484 Q + P ++G P Sbjct: 864 QGLLGAPGILGLP 876 Score = 32.0 bits (71), Expect = 7.2 Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 13/137 (9%) Query: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKP-PTPASTPHSQIPPLPGMS-------RSN 1183 P PAG+ +GP PQ E G+ P P H+ + LPG++ Sbjct: 986 PVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPG 1045 Query: 1184 SVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSD 1243 SVG S ++ T +PG ++ + + G ++ P G P Sbjct: 1046 SVGPAGPRGPAGPSGPAGKDGRTGHPG---TVGPAGIRGPQGHQGPAGPPGP--PGPPGP 1100 Query: 1244 PFMSSGQGPNGGMGDPY 1260 P +S G G GD Y Sbjct: 1101 PGVSGGGYDFGYDGDFY 1117 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 100 bits (249), Expect = 2e-20 Identities = 172/702 (24%), Positives = 231/702 (32%), Gaps = 102/702 (14%) Query: 102 NSNGNAGPRPA-LNNNLTEP----PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGR 156 N +G++ PR +N T P PG S G A PPP + P + Sbjct: 114 NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF---PPSPQ 170 Query: 157 SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYY 216 P + A F P + +G +EP + P H Y Sbjct: 171 PPDSTPRQPEASFE--------PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP--QLY 220 Query: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK------PPPSSSASASSSSSSFAQQR 270 P + LS P G G GAA++ G PPP++ S SSS +S Sbjct: 221 PGGTGG-------VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGAS----- 268 Query: 271 FGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPA 330 GA P+ GG P+A P N +P+ P + S P GA P Sbjct: 269 -GAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG 327 Query: 331 DMAS-QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGK 389 + S G G S H+ + P SS P+ R P SS Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS-LPPASSSAPAPPM-RFPYSSSSSSSAAA 385 Query: 390 MRPQPYGGTN--PYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSY 447 ++ P+ Q PS P H +P P + P Q S Sbjct: 386 SSSSSSSSSSASPFPASQALPSYP---HSFP-PPTSLSVSNQPPKYTQPSLPSQAVWSQG 441 Query: 448 TQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQ 507 PPYG+ + G P P + PP T H QQQ Q Q Sbjct: 442 PPPPPPYGRLLANSNAHPG---------PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQ 492 Query: 508 PPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP-YQQQQPQ 566 Q Q Q + PP P +P H ++ P A SP +P Sbjct: 493 QQQQQQQQQQHHGNSGPPP----PGAFPHPLEGGSSH------HAHPYAMSPSLGSLRPY 542 Query: 567 QPAPSTLSQQAAYPQPQSQQSQQTAYSQ--QRFPPPQELSQDSFGSQASSAP-SMTSSKG 623 P P+ L P P SQ S YSQ PP S S + S P S S Sbjct: 543 PPGPAHL------PPPHSQVS----YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592 Query: 624 GQEDMNLSLQSRP------SSLPDLSGSIDDLPMGTEGALSPGVSTSG-ISSSQGEQSNP 676 G + P ++L + ++ P G + A PG G + S G Sbjct: 593 GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTA 652 Query: 677 AQSPFSPHTSPHL-----PGIRGPSPSPVG----SPASVAQSRSGPLSPAAVPGNQMPPR 727 + P + P PG RG SP P G P S GPL PA G P Sbjct: 653 TPPGYKPGSPPSFRTGTPPGYRGTSP-PAGPGTFKPGSPTVG-PGPLPPAGPSGLPSLPP 710 Query: 728 PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ--MPQYSSPQP 767 PP+ + P ++ + I Q+ P+ +P SP P Sbjct: 711 PPAAPASG---PPLSATQIKQEPAEEYETPESPVPPARSPSP 749 Score = 97.4 bits (241), Expect = 1e-19 Identities = 199/825 (24%), Positives = 263/825 (31%), Gaps = 151/825 (18%) Query: 225 PAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284 P P L S +PG + +++ K S + + + + G + Sbjct: 21 PGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESE 80 Query: 285 G--TPQPTATPTLNQLLT--SPSSARGYQGYP-GGDYSGGPQDGGAGKGPADMASQCWGA 339 T P T T +L SPS G D S P+D + G+ Sbjct: 81 SEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGS 140 Query: 340 AAAAA-AAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTP-QPSSPMDQMGKMRPQPYGG 397 + +++ S G + H P+ P S QP TP QP + + + P Y Sbjct: 141 VENDSDSSSGLSQGPARPYHPPPLFPPSP----QPPDSTPRQPEASFEPHPSVTPTGYHA 196 Query: 398 TN--PYSQQ-QGPPSGPQ-QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453 P S+ Q PP P YPG G + G A S G Q PP Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256 Query: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513 S G G P +P P S PP+ PH P+ P +P S Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLP--SAPPPANFPHVTPNLPPPPALRPLNNAS 314 Query: 514 SQPPYSQQPSQPPHQQSP----------APYPSQQSTTQQHPQSQPPYSQ----PQAQSP 559 + PP P H SP P P + T P S PP S P + P Sbjct: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374 Query: 560 YQQQQPQQPAPSTLSQQA---AYPQPQSQQSQQTAYSQQRFPPPQELS---------QDS 607 Y A S+ S + A P P SQ +S FPPP LS Q S Sbjct: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS---FPPPTSLSVSNQPPKYTQPS 431 Query: 608 FGSQA--SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSG 665 SQA S P G + + + P P +G+ + P VST Sbjct: 432 LPSQAVWSQGPPPPPPYGR---LLANSNAHPGPFPPSTGA--------QSTAHPPVSTHH 480 Query: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMP 725 Q +Q Q H SGP P A P Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQH-------------------HGNSGPPPPGAFP----- 516 Query: 726 PRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQ--PSGGQIHT 783 P G S HP S+ R Y P P + P P S +S Q P+G + + Sbjct: 517 -HPLEGGSSHHAHPYAMSPSLGSLRPY----PPGPAHLPP-PHSQVSYSQAGPNGPPVSS 570 Query: 784 GMGSYQQNSMGSYG---PQGGQYGPQGG-YPRQPNYNALPNANYPSAGMAGGINPMG--- 836 S S GSY P Q GPQG YP P +P SA ++ I + Sbjct: 571 SSNSSSSTSQGSYPCSHPSPSQ-GPQGAPYPFPP----VPTVTTSSATLSTVIATVASSP 625 Query: 837 AGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQE 896 AG + PG PPYG P ++ + Y P PP +G Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---PPSFRTGT------------- 669 Query: 897 TAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMA------GMINPQGPPYSM 950 PPGY GT PP G G G + P GP S Sbjct: 670 ---------------PPGY--------RGTSPPAGPGTFKPGSPTVGPGPLPPAGP--SG 704 Query: 951 GGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKS 995 ++ A A+ P + +K PA + P S S Sbjct: 705 LPSLPPPPAAPASGPPLSAT-QIKQEPAEEYETPESPVPPARSPS 748 Score = 68.6 bits (166), Expect = 7e-11 Identities = 130/559 (23%), Positives = 184/559 (32%), Gaps = 128/559 (22%) Query: 1124 KKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDL-KPPTPASTPH--SQIPPLPGMS 1180 K+ P P S + SG+ P T T+ GG+L P PA+ PH +PP P + Sbjct: 251 KQHPPPTTPISVSSSGASGAPPTKPPTTP--VGGGNLPSAPPPANFPHVTPNLPPPPALR 308 Query: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDM-MGRMSYEPNKDPYGSMRKA 1239 N+ S P PG+ PS + MG + P K P ++ + Sbjct: 309 PLNNA-----------SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGP--TLAPS 355 Query: 1240 PGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQ--------------HYPYGGP- 1284 P S P +S P M PYS ++ + YP+ P Sbjct: 356 PHSLP-PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP 414 Query: 1285 --------YDRVRTEPGIGPEGNMSTGAPQPN-----LMPSNPDSGMYSPS------RYP 1325 T+P + + S G P P L SN G + PS +P Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474 Query: 1326 P--------QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTY 1377 P QQQQQQQQ+ Q SG P P + P++G Sbjct: 475 PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA-----------FPHPLEG-- 521 Query: 1378 GPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPA 1437 H Y++ S G +P P P P SQ +Q P + N+ + Sbjct: 522 ---GSSHHAHPYAMSPSLGSLRPYPPG-PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS 577 Query: 1438 TATAA---TERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQ 1494 T+ + + P+ GPQ P+ F PP P + S +A Sbjct: 578 TSQGSYPCSHPSPSQGPQGA-PYPF-------PP--------VPTVTTSSATLSTVIATV 621 Query: 1495 GTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPP 1554 + G T S P P Y +RA G++ + P Sbjct: 622 ASSPAG-----------YKTASPPGPPPY------------GKRAPSPGAYKT--ATPPG 656 Query: 1555 YGPSAPVPPMTRPPPS--NYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMK 1612 Y P +P T PP PP P + P P P PS P L Sbjct: 657 YKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP---PAGPSGLPSLPPPPA 713 Query: 1613 MQKAGPPVPASHIAPAPVQ 1631 +GPP+ A+ I P + Sbjct: 714 APASGPPLSATQIKQEPAE 732 Score = 67.8 bits (164), Expect = 1e-10 Identities = 150/640 (23%), Positives = 198/640 (30%), Gaps = 143/640 (22%) Query: 17 PPP--PPSELKKAEQQQREEAGGEA--AAAAAAERGEMKAAAGQESEGPAVGPPQ----- 67 PPP PPS ++ EA E + M+ + + P PP Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220 Query: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGA--------EPDLKNSNGNAGPRPALNNNLTE 119 P G G GGG A S GGP P +S+G +G P T Sbjct: 221 PGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT--KPPTT 278 Query: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP 179 P GGG S+ PH PPPA SP + A Q G Sbjct: 279 PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA-------QPLPGHLPS 331 Query: 180 GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTP 239 A Q GG P GP H P P S+ P P + SS Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLP--------PASSSAPAPPMRFPYSS------ 377 Query: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLL 299 S +++AA S SSS+SAS +S A + S + P P+L Sbjct: 378 -SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL---- 432 Query: 300 TSPSSARGYQGYPGGD-YSGGPQDGGAGKGPADMASQCWGAAAAAAAA------------ 346 PS A QG P Y + A GP ++ A + Sbjct: 433 --PSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ 490 Query: 347 -AAASGGAQQRSHHAPMSPGSSGGGGQPL----ARTPQPSSPMDQMGKMRPQPYGGTN-- 399 QQ+ HH P G PL + P + +G +RP P G + Sbjct: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP 550 Query: 400 -PYSQ---QQGPPSGP------------QQGHGYPGQPYGSQTPQRYPM----------- 432 P+SQ Q P+GP QG P SQ PQ P Sbjct: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610 Query: 433 -----TMQGRAQSAMGGLSYTQQI--PPYGQQGPS----------GYG-------QQGQT 468 T+ S+ G PPYG++ PS GY + G Sbjct: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670 Query: 469 PYYNQQSPHPQQ------------------------QQPPYSQQPPSQTPHAQPSYQQQP 504 P Y SP PP P S P + +Q+P Sbjct: 671 PGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP 730 Query: 505 QSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQH 544 + +S PP ++ PS PP + SQ + +H Sbjct: 731 AEEYETPESPVPP-ARSPSPPPKVVDVPSHASQSARFNKH 769 Score = 41.2 bits (95), Expect = 0.012 Identities = 81/374 (21%), Positives = 117/374 (31%), Gaps = 55/374 (14%) Query: 1286 DRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQ---QQQQQRHDSYGNQ 1342 D T P I G++ + + + P + P +PP Q +Q S+ Sbjct: 127 DNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPH 186 Query: 1343 FSTQGTPSGSPFPSQQTTMYQ-------QQQQNYKRPMDGTY-GPPAKRHEGEMYSVPYS 1394 S T +P + M+Q Q Y G GPP G S S Sbjct: 187 PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAAS---S 243 Query: 1395 TGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQ 1454 G +Q PP P S A+ P + P T P+ P Sbjct: 244 VGGPNGGKQHPPPTTPISVSSSGASGAPPTK----------PPTTPVGGGNLPSAPPPAN 293 Query: 1455 FPFQFGRDRVSAPPGTNAQQN---MPPQMMGGPIQASAEVAQQGTMWQGRNDMTYN---- 1507 FP + PP N PP + P+ + M QG + Sbjct: 294 FPHV--TPNLPPPPALRPLNNASASPPGLGAQPL--PGHLPSPHAMGQGMGGLPPGPEKG 349 Query: 1508 -------YANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAP 1560 ++ ++ SAP P + + + A+ S S P + P Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSS---SSAAASSSSSSSSSSASPFPASQALP 406 Query: 1561 VPPMTRPPPSNY----QPPPSMQNHIPQ--VSSPAPLPRPMENR----TSPSKSPFLHSG 1610 P + PPP++ QPP Q +P V S P P P R ++ PF S Sbjct: 407 SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST 466 Query: 1611 MKMQKAGPPVPASH 1624 A PPV H Sbjct: 467 GAQSTAHPPVSTHH 480 Score = 36.6 bits (83), Expect = 0.29 Identities = 84/382 (21%), Positives = 122/382 (31%), Gaps = 85/382 (22%) Query: 1085 SSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGP 1144 +S + S+ +Y Q + +G PPP + + P PPS + P Sbjct: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475 Query: 1145 ----------------QTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMS-------- 1180 Q Q G+ PP P + PH PL G S Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH----PLEGGSSHHAHPYA 531 Query: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMT-----PN-PGYQPSMNTSDMMGRMSY-----EPN 1229 S S+G + G + ++ PN P S N+S + SY P+ Sbjct: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS 591 Query: 1230 KDPYGSMRKAP-------------------GSDPFMSSGQGPNGGMGDPY-SRAAGPGLG 1269 + P G+ P S P P G PY RA PG Sbjct: 592 QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG--PPPYGKRAPSPGAY 649 Query: 1270 NVAMGPRQHYPYGGPYDRVRTEPG-------IGPEGNMSTGAPQ--PNLMPSNPDSGMYS 1320 A P + P P R T PG GP G G+P P +P SG+ S Sbjct: 650 KTAT-PPGYKPGSPPSFRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPLPPAGPSGLPS 707 Query: 1321 -------PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTT---MYQQQQQNYK 1370 P+ PP Q +Q + P+ SP P + + Q + Sbjct: 708 LPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFN 767 Query: 1371 RPMDGTYGPPAKRHEGEMYSVP 1392 + +D + A+ ++Y VP Sbjct: 768 KHLDRGFNSCAR---SDLYFVP 786 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.128 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 123,747,145 Number of Sequences: 37866 Number of extensions: 8492200 Number of successful extensions: 124166 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 787 Number of HSP's successfully gapped in prelim test: 2868 Number of HSP's that attempted gapping in prelim test: 41902 Number of HSP's gapped (non-prelim): 46660 length of query: 2285 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2167 effective length of database: 13,779,330 effective search space: 29859808110 effective search space used: 29859808110 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.