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Search of human proteins with 21040368
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040368 beta-site APP-cleaving enzyme 1 isoform D
preproprotein [Homo sapiens]
(432 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot... 891 0.0
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot... 877 0.0
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot... 870 0.0
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote... 592 e-169
gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprot... 267 1e-71
gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprot... 189 5e-48
gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprot... 169 6e-42
gi|4505757 progastricsin (pepsinogen C) [Homo sapiens] 68 2e-11
gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens] 67 3e-11
gi|119372302 pepsinogen 4, group I [Homo sapiens] 66 5e-11
gi|119372298 pepsinogen 3, group I [Homo sapiens] 66 5e-11
gi|23943854 pepsinogen 5, group I [Homo sapiens] 66 5e-11
gi|4503143 cathepsin D preproprotein [Homo sapiens] 54 3e-07
gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens] 52 1e-06
gi|4758754 napsin A preproprotein [Homo sapiens] 48 2e-05
gi|4506475 renin preproprotein [Homo sapiens] 47 3e-05
gi|195972905 zinc finger protein 385A isoform b [Homo sapiens] 36 0.078
gi|110349761 NSL1, MIND kinetochore complex component isoform 2 ... 33 0.38
gi|110349759 NSL1, MIND kinetochore complex component isoform 1 ... 33 0.38
gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ... 31 1.9
gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3... 31 2.5
gi|195972903 zinc finger protein 385A isoform a [Homo sapiens] 30 4.3
gi|24308079 zinc finger protein 385A isoform c [Homo sapiens] 30 4.3
gi|44890065 hypothetical protein LOC6936 [Homo sapiens] 30 5.6
gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens] 30 5.6
gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo sapi... 29 7.3
gi|40255133 hypothetical protein LOC222256 [Homo sapiens] 29 7.3
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 29 7.3
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 29 7.3
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 29 7.3
>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
[Homo sapiens]
Length = 432
Score = 891 bits (2303), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDLLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSL 180
YRDLRKGVYVPYTQGKWEGELGTDLLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSL
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDLLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSL 180
Query: 181 WYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSI 240
WYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSI
Sbjct: 181 WYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSI 240
Query: 241 KAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRP 300
KAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRP
Sbjct: 241 KAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRP 300
Query: 301 VEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTA 360
VEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTA
Sbjct: 301 VEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTA 360
Query: 361 AVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQ 420
AVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQ
Sbjct: 361 AVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQ 420
Query: 421 HDDFADDISLLK 432
HDDFADDISLLK
Sbjct: 421 HDDFADDISLLK 432
>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
[Homo sapiens]
Length = 457
Score = 877 bits (2267), Expect = 0.0
Identities = 432/457 (94%), Positives = 432/457 (94%), Gaps = 25/457 (5%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDL-------------------------LCGAGFPLNQ 155
YRDLRKGVYVPYTQGKWEGELGTDL LCGAGFPLNQ
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDLPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQ 180
Query: 156 SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD 215
SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD
Sbjct: 181 SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD 240
Query: 216 KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI 275
KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI
Sbjct: 241 KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI 300
Query: 276 SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV 335
SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV
Sbjct: 301 SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV 360
Query: 336 VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA 395
VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA
Sbjct: 361 VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA 420
Query: 396 ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 432
ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Sbjct: 421 ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 457
>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
[Homo sapiens]
Length = 476
Score = 870 bits (2248), Expect = 0.0
Identities = 432/476 (90%), Positives = 432/476 (90%), Gaps = 44/476 (9%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDL----------------------------------- 145
YRDLRKGVYVPYTQGKWEGELGTDL
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL 180
Query: 146 ---------LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIV 196
LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIV
Sbjct: 181 GLAYAEIARLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIV 240
Query: 197 RVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLG 256
RVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLG
Sbjct: 241 RVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLG 300
Query: 257 EQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAI 316
EQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAI
Sbjct: 301 EQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAI 360
Query: 317 SQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY 376
SQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY
Sbjct: 361 SQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY 420
Query: 377 NIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 432
NIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Sbjct: 421 NIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 476
>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
[Homo sapiens]
Length = 501
Score = 592 bits (1525), Expect = e-169
Identities = 287/287 (100%), Positives = 287/287 (100%)
Query: 146 LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL 205
LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL
Sbjct: 215 LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL 274
Query: 206 KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG 265
KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG
Sbjct: 275 KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG 334
Query: 266 TTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM 325
TTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM
Sbjct: 335 TTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM 394
Query: 326 GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST 385
GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST
Sbjct: 395 GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST 454
Query: 386 LMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 432
LMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Sbjct: 455 LMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 501
Score = 304 bits (779), Expect = 9e-83
Identities = 145/146 (99%), Positives = 146/146 (100%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDLL 146
YRDLRKGVYVPYTQGKWEGELGTDL+
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDLV 146
>gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprotein
[Homo sapiens]
Length = 518
Score = 267 bits (683), Expect = 1e-71
Identities = 131/287 (45%), Positives = 189/287 (65%), Gaps = 7/287 (2%)
Query: 146 LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL 205
+CGAG P+ S + GGS+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L
Sbjct: 232 MCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSL 288
Query: 206 KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG 265
+DC+EYN DK+IVDSGTT LRLP+KVF+A V+++ AS +F DGFW G QL CW
Sbjct: 289 NLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNS 348
Query: 266 TTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM 325
TPW+ FP IS+YL E +++SFRITILPQ Y++P+ + +CY+F IS S+ V+
Sbjct: 349 ETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNY-ECYRFGISPSTNALVI 407
Query: 326 GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST 385
GA +MEGFYV+FDRA+KR+GFA S C + + GPF T D+ E
Sbjct: 408 GATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPI 467
Query: 386 LMTIAYVMAAIC-ALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLL 431
L ++Y + ++C A+ ++ + L++ +RC R R + + +D S L
Sbjct: 468 LWIVSYALMSVCGAILLVLIVLLLLPFRCQR--RPRDPEVVNDESSL 512
Score = 109 bits (273), Expect = 4e-24
Identities = 51/93 (54%), Positives = 64/93 (68%)
Query: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
Query: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLL 146
+ SSTYR V V YTQG W G +G DL+
Sbjct: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLV 163
>gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprotein
[Homo sapiens]
Length = 396
Score = 189 bits (479), Expect = 5e-48
Identities = 85/151 (56%), Positives = 114/151 (75%), Gaps = 3/151 (1%)
Query: 146 LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL 205
+CGAG P+ S + GGS+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L
Sbjct: 232 MCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSL 288
Query: 206 KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG 265
+DC+EYN DK+IVDSGTT LRLP+KVF+A V+++ AS +F DGFW G QL CW
Sbjct: 289 NLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNS 348
Query: 266 TTPWNIFPVISLYLMGEVTNQSFRITILPQQ 296
TPW+ FP IS+YL E +++SFRITILPQ+
Sbjct: 349 ETPWSYFPKISIYLRDENSSRSFRITILPQK 379
Score = 109 bits (273), Expect = 4e-24
Identities = 51/93 (54%), Positives = 64/93 (68%)
Query: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
Query: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLL 146
+ SSTYR V V YTQG W G +G DL+
Sbjct: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLV 163
>gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprotein
[Homo sapiens]
Length = 468
Score = 169 bits (427), Expect = 6e-42
Identities = 100/287 (34%), Positives = 149/287 (51%), Gaps = 57/287 (19%)
Query: 146 LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDL 205
+CGAG P+ S + GGS+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L
Sbjct: 232 MCGAGLPVAGS---GTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSL 288
Query: 206 KMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG 265
+DC+EYN DK+IVDSGTT LRLP+KVF+A V+++ AS P G C++ G
Sbjct: 289 NLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLLYIQP-MMGAGLNYECYRFG 347
Query: 266 TTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM 325
+P S+ V+
Sbjct: 348 ISP--------------------------------------------------STNALVI 357
Query: 326 GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST 385
GA +MEGFYV+FDRA+KR+GFA S C + + GPF T D+ E
Sbjct: 358 GATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPI 417
Query: 386 LMTIAYVMAAIC-ALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLL 431
L ++Y + ++C A+ ++ + L++ +RC R R + + +D S L
Sbjct: 418 LWIVSYALMSVCGAILLVLIVLLLLPFRCQR--RPRDPEVVNDESSL 462
Score = 109 bits (273), Expect = 4e-24
Identities = 51/93 (54%), Positives = 64/93 (68%)
Query: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
Query: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLL 146
+ SSTYR V V YTQG W G +G DL+
Sbjct: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLV 163
>gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]
Length = 388
Score = 67.8 bits (164), Expect = 2e-11
Identities = 80/337 (23%), Positives = 133/337 (39%), Gaps = 82/337 (24%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYR------DL 124
Y+ E+++G+PPQ +L DTGSSN V + + H + SSTY L
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSL 132
Query: 125 RKG-----------------VYVPYTQ-GKWEGELGT-------DLLCGAGFP------- 152
+ G + VP + G E E GT D + G +P
Sbjct: 133 QYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEA 192
Query: 153 -------------------LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEV 193
+ S S GG+++ GG+D SLYTG +++ P+ +E Y+++
Sbjct: 193 TTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQI 252
Query: 194 IIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGF 253
I I GQ C E ++IVD+GT+ L +P++ A +++ A
Sbjct: 253 GIEEFLIGGQASGW-CSE--GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDE------- 302
Query: 254 WLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYK 313
G+ LV N + +L + + N + P Y+ T +
Sbjct: 303 -YGQFLV---------NCNSIQNLPSLTFIIN-GVEFPLPPSSYILSNNGYCTVGVEPTY 351
Query: 314 FAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSA 350
+ ++G V + +Y V+D R+GFA +A
Sbjct: 352 LSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA 388
>gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]
Length = 396
Score = 67.0 bits (162), Expect = 3e-11
Identities = 77/340 (22%), Positives = 125/340 (36%), Gaps = 92/340 (27%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 131 PYTQGKWEGELGTDL-------------------------------LCGAGFP------- 152
Y G G +G D + G G+P
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGV 197
Query: 153 --------------------LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYE 192
S G +I GG DHS ++GSL + P+ ++ Y++
Sbjct: 198 TPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQ 257
Query: 193 VIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDG 252
+ + +++ G M C E ++IVD+GT+ + P + +I AA DG
Sbjct: 258 IALDNIQVGG--TVMFCSE--GCQAIVDTGTSLITGPSDKIKQLQNAIGAAP-----VDG 308
Query: 253 FWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDC- 311
+ E N+ P ++ + G T+ P Y + D C
Sbjct: 309 EYAVE--------CANLNVMPDVTFTING------VPYTLSPTAY--TLLDFVDGMQFCS 352
Query: 312 --YKFAISQSSTGT--VMGAVIMEGFYVVFDRARKRIGFA 347
++ G ++G V + FY VFDR R+G A
Sbjct: 353 SGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392
>gi|119372302 pepsinogen 4, group I [Homo sapiens]
Length = 388
Score = 66.2 bits (160), Expect = 5e-11
Identities = 80/334 (23%), Positives = 130/334 (38%), Gaps = 85/334 (25%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL----HRYYQRQLSSTYRDLRKGVYV 130
Y+ + +G+P Q ++ DTGSSN V + L H + + SSTY+ + V +
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 131 PYTQGKWEGELGTDL-------------------------------LCGAGFPL------ 153
Y G G LG D + G +P
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGA 195
Query: 154 --------NQ---SEVLASV--------GGSMIIGGIDHSLYTGSLWYTPIRREWYYEVI 194
NQ S+ L SV G +I GGID S YTGSL + P+ E Y+++
Sbjct: 196 TPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQIT 255
Query: 195 IVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFW 254
+ + +NG+ + C E ++IVD+GT+ L P I A+ +++
Sbjct: 256 VDSITMNGEAIA--CAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGASENSD------- 304
Query: 255 LGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYK 313
G+ +V C + P +F T + + P Y+ E S
Sbjct: 305 -GDMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSEGSCISGFQGMN 352
Query: 314 FAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFA 347
++S ++G V + ++ VFDRA ++G A
Sbjct: 353 LP-TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|119372298 pepsinogen 3, group I [Homo sapiens]
Length = 388
Score = 66.2 bits (160), Expect = 5e-11
Identities = 80/334 (23%), Positives = 130/334 (38%), Gaps = 85/334 (25%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL----HRYYQRQLSSTYRDLRKGVYV 130
Y+ + +G+P Q ++ DTGSSN V + L H + + SSTY+ + V +
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 131 PYTQGKWEGELGTDL-------------------------------LCGAGFPL------ 153
Y G G LG D + G +P
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGA 195
Query: 154 --------NQ---SEVLASV--------GGSMIIGGIDHSLYTGSLWYTPIRREWYYEVI 194
NQ S+ L SV G +I GGID S YTGSL + P+ E Y+++
Sbjct: 196 TPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQIT 255
Query: 195 IVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFW 254
+ + +NG+ + C E ++IVD+GT+ L P I A+ +++
Sbjct: 256 VDSITMNGEAIA--CAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGASENSD------- 304
Query: 255 LGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYK 313
G+ +V C + P +F T + + P Y+ E S
Sbjct: 305 -GDMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSEGSCISGFQGMN 352
Query: 314 FAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFA 347
++S ++G V + ++ VFDRA ++G A
Sbjct: 353 LP-TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|23943854 pepsinogen 5, group I [Homo sapiens]
Length = 388
Score = 66.2 bits (160), Expect = 5e-11
Identities = 80/334 (23%), Positives = 130/334 (38%), Gaps = 85/334 (25%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL----HRYYQRQLSSTYRDLRKGVYV 130
Y+ + +G+P Q ++ DTGSSN V + L H + + SSTY+ + V +
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 131 PYTQGKWEGELGTDL-------------------------------LCGAGFPL------ 153
Y G G LG D + G +P
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGA 195
Query: 154 --------NQ---SEVLASV--------GGSMIIGGIDHSLYTGSLWYTPIRREWYYEVI 194
NQ S+ L SV G +I GGID S YTGSL + P+ E Y+++
Sbjct: 196 TPVFDNIWNQGLVSQDLFSVYLSADDKSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQIT 255
Query: 195 IVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFW 254
+ + +NG+ + C E ++IVD+GT+ L P I A+ +++
Sbjct: 256 VDSITMNGETIA--CAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGASENSD------- 304
Query: 255 LGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYK 313
G+ +V C + P +F T + + P Y+ E S
Sbjct: 305 -GDMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSEGSCISGFQGMN 352
Query: 314 FAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFA 347
++S ++G V + ++ VFDRA ++G A
Sbjct: 353 VP-TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|4503143 cathepsin D preproprotein [Homo sapiens]
Length = 412
Score = 53.9 bits (128), Expect = 3e-07
Identities = 57/198 (28%), Positives = 89/198 (44%), Gaps = 33/198 (16%)
Query: 160 ASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEI-NGQDLKMDCKEYNYDKSI 218
A GG +++GG D Y GSL Y + R+ Y++V + +VE+ +G L CKE ++I
Sbjct: 239 AQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTL---CKE--GCEAI 293
Query: 219 VDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLV-CWQAGTTPWNIFPVISL 277
VD+GT+ + P K+I A + GE ++ C + T P I+L
Sbjct: 294 VDTGTSLMVGPVDEVRELQKAIGAVPLIQ--------GEYMIPCEKVST-----LPAITL 340
Query: 278 YLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQ-----SSTGTVMGAVIMEG 332
L G+ S P+ Y V + C + S ++G V +
Sbjct: 341 KLGGKGYKLS------PEDYTLKVSQAGKTL--CLSGFMGMDIPPPSGPLWILGDVFIGR 392
Query: 333 FYVVFDRARKRIGFAVSA 350
+Y VFDR R+GFA +A
Sbjct: 393 YYTVFDRDNNRVGFAEAA 410
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 9/96 (9%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 128
YY E+ +G+PPQ ++ DTGSSN V + L H Y SSTY
Sbjct: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSF 138
Query: 129 YVPYTQGKWEGELGTDLLCGAGFPLNQSEVLASVGG 164
+ Y G G L D + P + +++GG
Sbjct: 139 DIHYGSGSLSGYLSQDTV---SVPCQSASSASALGG 171
>gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]
Length = 363
Score = 51.6 bits (122), Expect = 1e-06
Identities = 41/183 (22%), Positives = 66/183 (36%), Gaps = 62/183 (33%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 131 PYTQGKWEGELGTDL-------------------------------LCGAGFP------- 152
Y G G +G D + G G+P
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGV 197
Query: 153 --------------------LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYE 192
S G +I GG DHS ++GSL + P+ ++ Y++
Sbjct: 198 TPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQ 257
Query: 193 VII 195
+ +
Sbjct: 258 IAL 260
>gi|4758754 napsin A preproprotein [Homo sapiens]
Length = 420
Score = 47.8 bits (112), Expect = 2e-05
Identities = 75/300 (25%), Positives = 115/300 (38%), Gaps = 80/300 (26%)
Query: 6 PWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLG--LRLPRETDEEPE----EPGRRGS 59
P LLL V P+ T IR+PL G + LR RE E P+ PG +
Sbjct: 9 PLLLLLPLLNVEPSGATL--IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPI 66
Query: 60 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYY 113
FV + N R Y+ E+ +G+PPQ + DTGSSN V + F LH +
Sbjct: 67 FVPL-SNYRDVQ---YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRF 122
Query: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLL--------------------------- 146
+ SS+++ + Y G+ +G L D L
Sbjct: 123 DPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAH 182
Query: 147 ----CGAGFPLNQSE-------VLASV--------------------GGSMIIGGIDHSL 175
G GFP+ E VL GG +++GG D +
Sbjct: 183 FDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAH 242
Query: 176 YTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 235
Y L + P+ Y+++ + RV++ G L + K +I+D+GT+ + P + A
Sbjct: 243 YIPPLTFVPVTVPAYWQIHMERVKV-GPGLTLCAKGC---AAILDTGTSLITGPTEEIRA 298
>gi|4506475 renin preproprotein [Homo sapiens]
Length = 406
Score = 47.4 bits (111), Expect = 3e-05
Identities = 76/327 (23%), Positives = 125/327 (38%), Gaps = 59/327 (18%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 128
YY E+ +G+PPQT ++ DTGSSN V ++ L H+ + SS+Y+ +
Sbjct: 86 YYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTEL 145
Query: 129 YVPYTQGKWEGELGTDLLCGAGFPLNQ--SEV---------LASVGGSMIIGGIDHSL-- 175
+ Y+ G G L D++ G + Q EV LA G + +G I+ ++
Sbjct: 146 TLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGR 205
Query: 176 ---YTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK- 231
++ + +E + R N Q L D + + L K
Sbjct: 206 VTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTG 265
Query: 232 VFEAAVKSIKAASSTEKFPDG-FWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRI 290
V++ +K + SST DG L + + +G+T S+ + E R+
Sbjct: 266 VWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTS-------SIEKLMEALGAKKRL 318
Query: 291 ----------TILP--QQYLRPVEDVATSQDDCYKFAISQSSTGTV-------------- 324
LP +L E TS D ++ + S T+
Sbjct: 319 FDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPT 378
Query: 325 --MGAVIMEGFYVVFDRARKRIGFAVS 349
+GA + FY FDR RIGFA++
Sbjct: 379 WALGATFIRKFYTEFDRRNNRIGFALA 405
>gi|195972905 zinc finger protein 385A isoform b [Homo sapiens]
Length = 305
Score = 35.8 bits (81), Expect = 0.078
Identities = 23/59 (38%), Positives = 29/59 (49%)
Query: 13 GAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKS 71
G GV P GT+H L RSGLG RL T EPE P + +F + N++ S
Sbjct: 133 GDGVAPRPGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNS 191
>gi|110349761 NSL1, MIND kinetochore complex component isoform 2
[Homo sapiens]
Length = 213
Score = 33.5 bits (75), Expect = 0.38
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 188 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 235
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
Query: 236 AVKSIKA 242
+K+IKA
Sbjct: 137 VIKTIKA 143
>gi|110349759 NSL1, MIND kinetochore complex component isoform 1
[Homo sapiens]
Length = 281
Score = 33.5 bits (75), Expect = 0.38
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 188 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 235
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
Query: 236 AVKSIKA 242
+K+IKA
Sbjct: 137 VIKTIKA 143
>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2
[Homo sapiens]
Length = 1461
Score = 31.2 bits (69), Expect = 1.9
Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 17/121 (14%)
Query: 26 IRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNL------RGKSGQGYYVEM 79
+ +P+ S LG + P E+ + G + ++ +D G Q ++
Sbjct: 687 LNIPILSSLGSSA-----PSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDK 741
Query: 80 TVGSPPQTLNIL---VDTGSSNFAVGAAPHPFLHRYYQRQLS---STYRDLRKGVYVPYT 133
S T+++L + GSS + +P P Y R+LS STYR G PY
Sbjct: 742 PTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYK 801
Query: 134 Q 134
Q
Sbjct: 802 Q 802
>gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
[Homo sapiens]
Length = 406
Score = 30.8 bits (68), Expect = 2.5
Identities = 32/114 (28%), Positives = 41/114 (35%), Gaps = 32/114 (28%)
Query: 41 LRLP---RETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSS 97
L+LP R P + G ++ E L G G +PP TL +L+D GS
Sbjct: 91 LQLPQWRRRRPPAPRDDGEEAAWEEESPGLSGGPGGSGAGSTVAEAPPGTLALLLDEGSK 150
Query: 98 NF---------------------------AVGAAPHPFLHRYYQRQLSSTYRDL 124
AVGA PH F R Y + L + YRDL
Sbjct: 151 QLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPH-FFDRSYDKGL-AWYRDL 202
>gi|195972903 zinc finger protein 385A isoform a [Homo sapiens]
Length = 386
Score = 30.0 bits (66), Expect = 4.3
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 17 LPAH--GTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKS 71
L AH GT+H L RSGLG RL T EPE P + +F + N++ S
Sbjct: 216 LEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNS 272
>gi|24308079 zinc finger protein 385A isoform c [Homo sapiens]
Length = 366
Score = 30.0 bits (66), Expect = 4.3
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 17 LPAH--GTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKS 71
L AH GT+H L RSGLG RL T EPE P + +F + N++ S
Sbjct: 196 LEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNS 252
>gi|44890065 hypothetical protein LOC6936 [Homo sapiens]
Length = 781
Score = 29.6 bits (65), Expect = 5.6
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 36 GAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQG 74
GAP L +P +EEP G R + +RG G+G
Sbjct: 30 GAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRG 68
>gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens]
Length = 497
Score = 29.6 bits (65), Expect = 5.6
Identities = 11/40 (27%), Positives = 22/40 (55%)
Query: 254 WLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITIL 293
++ L+ W TPW ++ +IS+ ++G V Q + +L
Sbjct: 99 FVAANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVL 138
>gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo
sapiens]
Length = 588
Score = 29.3 bits (64), Expect = 7.3
Identities = 23/89 (25%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 23 QHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVG 82
+HG + LR G G PLG+ + E +G V + G E G
Sbjct: 198 KHGGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVLAL----ADDGASVLFEAAGG 253
Query: 83 SPPQTLNILVDTGSSNFAVGAAPHPFLHR 111
P +++L++ G S A H +HR
Sbjct: 254 GNPDCISLLLEYGGSGNVPNRAGHLPIHR 282
>gi|40255133 hypothetical protein LOC222256 [Homo sapiens]
Length = 885
Score = 29.3 bits (64), Expect = 7.3
Identities = 17/57 (29%), Positives = 26/57 (45%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVP 131
Y + + S + LV+TG+ ++ PHP + TY+ LRK VY P
Sbjct: 651 YVTDDNLMSDRKKAEALVETGTVTLSIKVIPHPTTIITTTPRPRVTYQVLRKNVYSP 707
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 29.3 bits (64), Expect = 7.3
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 148 GAGFPLNQSEVLASVGGSMI----IGGIDHSLYTGSLWYTPIRREWYYEVII 195
GAG N+ V++ G S + + GI + LY LW T I +W Y++ +
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGI-YLLYLQDLWTTVIDMKWRYKLTL 69
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 29.3 bits (64), Expect = 7.3
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 148 GAGFPLNQSEVLASVGGSMI----IGGIDHSLYTGSLWYTPIRREWYYEVII 195
GAG N+ V++ G S + + GI + LY LW T I +W Y++ +
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGI-YLLYLQDLWTTVIDMKWRYKLTL 69
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 29.3 bits (64), Expect = 7.3
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 148 GAGFPLNQSEVLASVGGSMI----IGGIDHSLYTGSLWYTPIRREWYYEVII 195
GAG N+ V++ G S + + GI + LY LW T I +W Y++ +
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGI-YLLYLQDLWTTVIDMKWRYKLTL 69
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,896,370
Number of Sequences: 37866
Number of extensions: 777170
Number of successful extensions: 1688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1637
Number of HSP's gapped (non-prelim): 49
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.