Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 21040364
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040364 beta-site APP-cleaving enzyme 1 isoform C
preproprotein [Homo sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot... 942 0.0
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote... 921 0.0
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot... 877 0.0
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot... 875 0.0
gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprot... 385 e-107
gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprot... 306 3e-83
gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprot... 286 3e-77
gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens] 75 2e-13
gi|4503143 cathepsin D preproprotein [Homo sapiens] 74 2e-13
gi|4505757 progastricsin (pepsinogen C) [Homo sapiens] 74 4e-13
gi|119372302 pepsinogen 4, group I [Homo sapiens] 72 1e-12
gi|119372298 pepsinogen 3, group I [Homo sapiens] 72 1e-12
gi|23943854 pepsinogen 5, group I [Homo sapiens] 71 2e-12
gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens] 59 7e-09
gi|4506475 renin preproprotein [Homo sapiens] 58 2e-08
gi|4758754 napsin A preproprotein [Homo sapiens] 50 4e-06
gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ... 37 0.049
gi|195972905 zinc finger protein 385A isoform b [Homo sapiens] 36 0.083
gi|110349761 NSL1, MIND kinetochore complex component isoform 2 ... 33 0.41
gi|110349759 NSL1, MIND kinetochore complex component isoform 1 ... 33 0.41
gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3... 31 2.7
gi|195972903 zinc finger protein 385A isoform a [Homo sapiens] 30 4.6
gi|24308079 zinc finger protein 385A isoform c [Homo sapiens] 30 4.6
gi|44890065 hypothetical protein LOC6936 [Homo sapiens] 30 5.9
gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens] 30 5.9
gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo sapi... 29 7.8
gi|40255133 hypothetical protein LOC222256 [Homo sapiens] 29 7.8
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 29 7.8
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 29 7.8
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 29 7.8
>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
[Homo sapiens]
Length = 457
Score = 942 bits (2435), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDLPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQ 180
YRDLRKGVYVPYTQGKWEGELGTDLPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQ
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDLPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQ 180
Query: 181 SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD 240
SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD
Sbjct: 181 SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD 240
Query: 241 KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI 300
KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI
Sbjct: 241 KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI 300
Query: 301 SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV 360
SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV
Sbjct: 301 SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV 360
Query: 361 VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA 420
VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA
Sbjct: 361 VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA 420
Query: 421 ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 457
ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Sbjct: 421 ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 457
>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
[Homo sapiens]
Length = 501
Score = 921 bits (2380), Expect = 0.0
Identities = 457/501 (91%), Positives = 457/501 (91%), Gaps = 44/501 (8%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDL----------------------------------- 145
YRDLRKGVYVPYTQGKWEGELGTDL
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL 180
Query: 146 ---------PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 196
PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 197 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 256
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 257 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT 316
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
Sbjct: 301 VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT 360
Query: 317 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC 376
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
Sbjct: 361 ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC 420
Query: 377 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW 436
HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
Sbjct: 421 HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW 480
Query: 437 RCLRCLRQQHDDFADDISLLK 457
RCLRCLRQQHDDFADDISLLK
Sbjct: 481 RCLRCLRQQHDDFADDISLLK 501
>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
[Homo sapiens]
Length = 432
Score = 877 bits (2267), Expect = 0.0
Identities = 432/457 (94%), Positives = 432/457 (94%), Gaps = 25/457 (5%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDLPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQ 180
YRDLRKGVYVPYTQGKWEGELGTDL LCGAGFPLNQ
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDL-------------------------LCGAGFPLNQ 155
Query: 181 SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD 240
SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD
Sbjct: 156 SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYD 215
Query: 241 KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI 300
KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI
Sbjct: 216 KSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI 275
Query: 301 SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV 360
SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV
Sbjct: 276 SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYV 335
Query: 361 VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA 420
VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA
Sbjct: 336 VFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAA 395
Query: 421 ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 457
ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Sbjct: 396 ICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 432
>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
[Homo sapiens]
Length = 476
Score = 875 bits (2261), Expect = 0.0
Identities = 434/476 (91%), Positives = 444/476 (93%), Gaps = 19/476 (3%)
Query: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF
Sbjct: 1 MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSF 60
Query: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST 120
Query: 121 YRDLRKGVYVPYTQGKWEGELGTDL------PDDSLEPFFDSLVKQ-------THVPNLF 167
YRDLRKGVYVPYTQGKWEGELGTDL P+ ++ ++ + ++ +
Sbjct: 121 YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL 180
Query: 168 SL------QLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIV 221
L +LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIV
Sbjct: 181 GLAYAEIARLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIV 240
Query: 222 RVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLG 281
RVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLG
Sbjct: 241 RVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLG 300
Query: 282 EQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAI 341
EQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAI
Sbjct: 301 EQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAI 360
Query: 342 SQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY 401
SQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY
Sbjct: 361 SQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY 420
Query: 402 NIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 457
NIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Sbjct: 421 NIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 476
>gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprotein
[Homo sapiens]
Length = 518
Score = 385 bits (988), Expect = e-107
Identities = 198/448 (44%), Positives = 272/448 (60%), Gaps = 51/448 (11%)
Query: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
Query: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDL---------------------------- 145
+ SSTYR V V YTQG W G +G DL
Sbjct: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
Query: 146 ----------------PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG 189
P SLE FFDSLV Q ++PN+FS+Q+CGAG P+ S + GG
Sbjct: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
Query: 190 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 249
S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
Query: 250 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 309
LRLP+KVF+A V+++ AS +F DGFW G QL CW TPW+ FP IS+YL E +
Sbjct: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
Query: 310 NQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRI 369
++SFRITILPQ Y++P+ + +CY+F IS S+ V+GA +MEGFYV+FDRA+KR+
Sbjct: 368 SRSFRITILPQLYIQPMMGAGLNY-ECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRV 426
Query: 370 GFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAIC-ALFMLP 428
GFA S C + + GPF T D+ E L ++Y + ++C A+ ++
Sbjct: 427 GFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVL 486
Query: 429 LCLMVCQWRCLRCLRQQHDDFADDISLL 456
+ L++ +RC R R + + +D S L
Sbjct: 487 IVLLLLPFRCQR--RPRDPEVVNDESSL 512
>gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprotein
[Homo sapiens]
Length = 396
Score = 306 bits (784), Expect = 3e-83
Identities = 152/312 (48%), Positives = 197/312 (63%), Gaps = 47/312 (15%)
Query: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
Query: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDL---------------------------- 145
+ SSTYR V V YTQG W G +G DL
Sbjct: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
Query: 146 ----------------PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG 189
P SLE FFDSLV Q ++PN+FS+Q+CGAG P+ S + GG
Sbjct: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
Query: 190 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 249
S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
Query: 250 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 309
LRLP+KVF+A V+++ AS +F DGFW G QL CW TPW+ FP IS+YL E +
Sbjct: 308 LLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS 367
Query: 310 NQSFRITILPQQ 321
++SFRITILPQ+
Sbjct: 368 SRSFRITILPQK 379
>gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprotein
[Homo sapiens]
Length = 468
Score = 286 bits (732), Expect = 3e-77
Identities = 167/448 (37%), Positives = 232/448 (51%), Gaps = 101/448 (22%)
Query: 54 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY 113
P +F+ MVDNL+G SG+GYY+EM +G+PPQ L ILVDTGSSNFAV PH ++ Y+
Sbjct: 71 PAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYF 130
Query: 114 QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDL---------------------------- 145
+ SSTYR V V YTQG W G +G DL
Sbjct: 131 DTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPG 190
Query: 146 ----------------PDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGG 189
P SLE FFDSLV Q ++PN+FS+Q+CGAG P+ S + GG
Sbjct: 191 IKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGS---GTNGG 247
Query: 190 SMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTT 249
S+++GGI+ SLY G +WYTPI+ EWYY++ I+++EI GQ L +DC+EYN DK+IVDSGTT
Sbjct: 248 SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT 307
Query: 250 NLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVT 309
LRLP+KVF+A V+++ AS P G C++ G +P
Sbjct: 308 LLRLPQKVFDAVVEAVARASLLYIQP-MMGAGLNYECYRFGISP---------------- 350
Query: 310 NQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRI 369
S+ V+GA +MEGFYV+FDRA+KR+
Sbjct: 351 ----------------------------------STNALVIGATVMEGFYVIFDRAQKRV 376
Query: 370 GFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAIC-ALFMLP 428
GFA S C + + GPF T D+ E L ++Y + ++C A+ ++
Sbjct: 377 GFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVL 436
Query: 429 LCLMVCQWRCLRCLRQQHDDFADDISLL 456
+ L++ +RC R R + + +D S L
Sbjct: 437 IVLLLLPFRCQR--RPRDPEVVNDESSL 462
>gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]
Length = 396
Score = 74.7 bits (182), Expect = 2e-13
Identities = 82/347 (23%), Positives = 133/347 (38%), Gaps = 81/347 (23%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 131 PYTQGKWEGELGTD----------------------------------------LPDDSL 150
Y G G +G D L +
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGV 197
Query: 151 EPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPI 210
P FD+++ Q NL L + N G +I GG DHS ++GSL + P+
Sbjct: 198 TPVFDNMMAQ----NLVDLPMFSVYMSSNPE---GGAGSELIFGGYDHSHFSGSLNWVPV 250
Query: 211 RREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASS 270
++ Y+++ + +++ G M C E ++IVD+GT+ + P + +I AA
Sbjct: 251 TKQAYWQIALDNIQVGG--TVMFCSE--GCQAIVDTGTSLITGPSDKIKQLQNAIGAAP- 305
Query: 271 TEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVA 330
DG + E N+ P ++ + G T+ P Y + D
Sbjct: 306 ----VDGEYAVE--------CANLNVMPDVTFTING------VPYTLSPTAY--TLLDFV 345
Query: 331 TSQDDC---YKFAISQSSTGT--VMGAVIMEGFYVVFDRARKRIGFA 372
C ++ G ++G V + FY VFDR R+G A
Sbjct: 346 DGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392
>gi|4503143 cathepsin D preproprotein [Homo sapiens]
Length = 412
Score = 74.3 bits (181), Expect = 2e-13
Identities = 99/366 (27%), Positives = 147/366 (40%), Gaps = 99/366 (27%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYR------ 122
YY E+ +G+PPQ ++ DTGSSN V + L H Y SSTY
Sbjct: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSF 138
Query: 123 DLRKG------------VYVP------------------------------YTQGKWEGE 140
D+ G V VP + K++G
Sbjct: 139 DIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGI 198
Query: 141 LGTDLPDDSLE---PFFDSLVKQTHVP-NLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 196
LG P S+ P FD+L++Q V N+FS L + A GG +++GG
Sbjct: 199 LGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYL--------SRDPDAQPGGELMLGGT 250
Query: 197 DHSLYTGSLWYTPIRREWYYEVIIVRVEI-NGQDLKMDCKEYNYDKSIVDSGTTNLRLPK 255
D Y GSL Y + R+ Y++V + +VE+ +G L CKE ++IVD+GT+ + P
Sbjct: 251 DSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTL---CKE--GCEAIVDTGTSLMVGPV 305
Query: 256 KVFEAAVKSIKAASSTEKFPDGFWLGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFR 314
K+I A + GE ++ C + T P I+L L G+ S
Sbjct: 306 DEVRELQKAIGAVPLIQ--------GEYMIPCEKVST-----LPAITLKLGGKGYKLS-- 350
Query: 315 ITILPQQYLRPVEDVATSQDDCYKFAISQ-----SSTGTVMGAVIMEGFYVVFDRARKRI 369
P+ Y V + C + S ++G V + +Y VFDR R+
Sbjct: 351 ----PEDYTLKVSQAGKTL--CLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRV 404
Query: 370 GFAVSA 375
GFA +A
Sbjct: 405 GFAEAA 410
>gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]
Length = 388
Score = 73.6 bits (179), Expect = 4e-13
Identities = 83/338 (24%), Positives = 140/338 (41%), Gaps = 59/338 (17%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Y+ E+++G+PPQ +L DTGSSN V + + H + SSTY + +
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSL 132
Query: 131 PYTQGKWEGELGTD--------LPDDSL-----EPF-------FDSLVKQTHVPNLF--- 167
Y G G G D +P+ EP FD ++ + P L
Sbjct: 133 QYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY-PALSVDE 191
Query: 168 ---SLQ-------LCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYE 217
++Q L F + S S GG+++ GG+D SLYTG +++ P+ +E Y++
Sbjct: 192 ATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQ 251
Query: 218 VIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDG 277
+ I I GQ C E ++IVD+GT+ L +P++ A +++ A
Sbjct: 252 IGIEEFLIGGQASGW-CSE--GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDE------ 302
Query: 278 FWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCY 337
G+ LV N + +L + + N + P Y+ T +
Sbjct: 303 --YGQFLV---------NCNSIQNLPSLTFIIN-GVEFPLPPSSYILSNNGYCTVGVEPT 350
Query: 338 KFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSA 375
+ ++G V + +Y V+D R+GFA +A
Sbjct: 351 YLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA 388
>gi|119372302 pepsinogen 4, group I [Homo sapiens]
Length = 388
Score = 71.6 bits (174), Expect = 1e-12
Identities = 85/344 (24%), Positives = 138/344 (40%), Gaps = 80/344 (23%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL----HRYYQRQLSSTYRDLRKGVYV 130
Y+ + +G+P Q ++ DTGSSN V + L H + + SSTY+ + V +
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 131 PYTQGKWEGELGTDL---------------------------PDDSL------------- 150
Y G G LG D P D +
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGA 195
Query: 151 EPFFDSLVKQTHVP-NLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTP 209
P FD++ Q V +LFS+ L +QS G +I GGID S YTGSL + P
Sbjct: 196 TPVFDNIWNQGLVSQDLFSVYLSAD----DQS------GSVVIFGGIDSSYYTGSLNWVP 245
Query: 210 IRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 269
+ E Y+++ + + +NG+ + C E ++IVD+GT+ L P I A+
Sbjct: 246 VTVEGYWQITVDSITMNGEAIA--CAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGASE 301
Query: 270 STEKFPDGFWLGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVED 328
+++ G+ +V C + P +F T + + P Y+ E
Sbjct: 302 NSD--------GDMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSEG 342
Query: 329 VATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFA 372
S ++S ++G V + ++ VFDRA ++G A
Sbjct: 343 SCISGFQGMNLP-TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|119372298 pepsinogen 3, group I [Homo sapiens]
Length = 388
Score = 71.6 bits (174), Expect = 1e-12
Identities = 85/344 (24%), Positives = 138/344 (40%), Gaps = 80/344 (23%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL----HRYYQRQLSSTYRDLRKGVYV 130
Y+ + +G+P Q ++ DTGSSN V + L H + + SSTY+ + V +
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 131 PYTQGKWEGELGTDL---------------------------PDDSL------------- 150
Y G G LG D P D +
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGA 195
Query: 151 EPFFDSLVKQTHVP-NLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTP 209
P FD++ Q V +LFS+ L +QS G +I GGID S YTGSL + P
Sbjct: 196 TPVFDNIWNQGLVSQDLFSVYLSAD----DQS------GSVVIFGGIDSSYYTGSLNWVP 245
Query: 210 IRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 269
+ E Y+++ + + +NG+ + C E ++IVD+GT+ L P I A+
Sbjct: 246 VTVEGYWQITVDSITMNGEAIA--CAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGASE 301
Query: 270 STEKFPDGFWLGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVED 328
+++ G+ +V C + P +F T + + P Y+ E
Sbjct: 302 NSD--------GDMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSEG 342
Query: 329 VATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFA 372
S ++S ++G V + ++ VFDRA ++G A
Sbjct: 343 SCISGFQGMNLP-TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|23943854 pepsinogen 5, group I [Homo sapiens]
Length = 388
Score = 70.9 bits (172), Expect = 2e-12
Identities = 83/344 (24%), Positives = 135/344 (39%), Gaps = 80/344 (23%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL----HRYYQRQLSSTYRDLRKGVYV 130
Y+ + +G+P Q ++ DTGSSN V + L H + + SSTY+ + V +
Sbjct: 76 YFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSI 135
Query: 131 PYTQGKWEGELGTDL---------------------------PDDSL------------- 150
Y G G LG D P D +
Sbjct: 136 TYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGA 195
Query: 151 EPFFDSLVKQTHVP-NLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTP 209
P FD++ Q V +LFS+ L G +I GGID S YTGSL + P
Sbjct: 196 TPVFDNIWNQGLVSQDLFSVYLSADD----------KSGSVVIFGGIDSSYYTGSLNWVP 245
Query: 210 IRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 269
+ E Y+++ + + +NG+ + C E ++IVD+GT+ L P I A+
Sbjct: 246 VTVEGYWQITVDSITMNGETIA--CAE--GCQAIVDTGTSLLTGPTSPIANIQSDIGASE 301
Query: 270 STEKFPDGFWLGEQLV-CWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVED 328
+++ G+ +V C + P +F T + + P Y+ E
Sbjct: 302 NSD--------GDMVVSCSAISSLPDIVF-----------TINGVQYPVPPSAYILQSEG 342
Query: 329 VATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFA 372
S ++S ++G V + ++ VFDRA ++G A
Sbjct: 343 SCISGFQGMNVP-TESGELWILGDVFIRQYFTVFDRANNQVGLA 385
>gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]
Length = 363
Score = 59.3 bits (142), Expect = 7e-09
Identities = 46/190 (24%), Positives = 74/190 (38%), Gaps = 51/190 (26%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 131 PYTQGKWEGELGTD----------------------------------------LPDDSL 150
Y G G +G D L +
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGV 197
Query: 151 EPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPI 210
P FD+++ Q NL L + N G +I GG DHS ++GSL + P+
Sbjct: 198 TPVFDNMMAQ----NLVDLPMFSVYMSSNPE---GGAGSELIFGGYDHSHFSGSLNWVPV 250
Query: 211 RREWYYEVII 220
++ Y+++ +
Sbjct: 251 TKQAYWQIAL 260
>gi|4506475 renin preproprotein [Homo sapiens]
Length = 406
Score = 58.2 bits (139), Expect = 2e-08
Identities = 75/345 (21%), Positives = 135/345 (39%), Gaps = 70/345 (20%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 128
YY E+ +G+PPQT ++ DTGSSN V ++ L H+ + SS+Y+ +
Sbjct: 86 YYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTEL 145
Query: 129 YVPYTQGKWEGELGTDL---PDDSLEPFFDSLVKQTHVPNL-----------FSLQLCGA 174
+ Y+ G G L D+ ++ F + + +P + F Q G
Sbjct: 146 TLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGR 205
Query: 175 GFPL--------------------NQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREW 214
P+ SE S+GG +++GG D Y G+ Y + +
Sbjct: 206 VTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTG 265
Query: 215 YYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKF 274
+++ + V + L + + ++VD+G + + + SS EK
Sbjct: 266 VWQIQMKGVSVGSSTLLCE----DGCLALVDTGASYIS-------------GSTSSIEKL 308
Query: 275 PDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQD 334
+ ++L + P IS +L G+ T+ Y+ ++ +S+
Sbjct: 309 MEALGAKKRLFDYVVKCNEGPTLPDISFHLGGK------EYTLTSADYV--FQESYSSKK 360
Query: 335 DC----YKFAISQSSTGT-VMGAVIMEGFYVVFDRARKRIGFAVS 374
C + I + T +GA + FY FDR RIGFA++
Sbjct: 361 LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>gi|4758754 napsin A preproprotein [Homo sapiens]
Length = 420
Score = 50.1 bits (118), Expect = 4e-06
Identities = 83/308 (26%), Positives = 126/308 (40%), Gaps = 71/308 (23%)
Query: 6 PWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLG--LRLPRETDEEPE----EPGRRGS 59
P LLL V P+ T IR+PL G + LR RE E P+ PG +
Sbjct: 9 PLLLLLPLLNVEPSGATL--IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPI 66
Query: 60 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYY 113
FV + N R Y+ E+ +G+PPQ + DTGSSN V + F LH +
Sbjct: 67 FVPL-SNYRDVQ---YFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRF 122
Query: 114 QRQLSSTYRDLR--------------------------KGVYVPYTQGKWE--------- 138
+ SS+++ KG V + + WE
Sbjct: 123 DPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAH 182
Query: 139 --GELGTDLPDDSLE---PFFDSLVKQTHVPN-LFSLQLCGAGFPLNQSEVLASVGGSMI 192
G LG P S+E P D LV+Q + +FS F LN+ GG ++
Sbjct: 183 FDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFS-------FYLNRDPEEPD-GGELV 234
Query: 193 IGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLR 252
+GG D + Y L + P+ Y+++ + RV++ G L + K +I+D+GT+ +
Sbjct: 235 LGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKV-GPGLTLCAKGC---AAILDTGTSLIT 290
Query: 253 LPKKVFEA 260
P + A
Sbjct: 291 GPTEEIRA 298
>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2
[Homo sapiens]
Length = 1461
Score = 36.6 bits (83), Expect = 0.049
Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 17/141 (12%)
Query: 26 IRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNL------RGKSGQGYYVEM 79
+ +P+ S LG + P E+ + G + ++ +D G Q ++
Sbjct: 687 LNIPILSSLGSSA-----PSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDK 741
Query: 80 TVGSPPQTLNIL---VDTGSSNFAVGAAPHPFLHRYYQRQLS---STYRDLRKGVYVPYT 133
S T+++L + GSS + +P P Y R+LS STYR G PY
Sbjct: 742 PTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYK 801
Query: 134 QGKWEGELGTDLPDDSLEPFF 154
Q E + L D S E F+
Sbjct: 802 QPSDGMERPSSLMDSSQEKFY 822
>gi|195972905 zinc finger protein 385A isoform b [Homo sapiens]
Length = 305
Score = 35.8 bits (81), Expect = 0.083
Identities = 23/59 (38%), Positives = 29/59 (49%)
Query: 13 GAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKS 71
G GV P GT+H L RSGLG RL T EPE P + +F + N++ S
Sbjct: 133 GDGVAPRPGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNS 191
>gi|110349761 NSL1, MIND kinetochore complex component isoform 2
[Homo sapiens]
Length = 213
Score = 33.5 bits (75), Expect = 0.41
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 213 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 260
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
Query: 261 AVKSIKA 267
+K+IKA
Sbjct: 137 VIKTIKA 143
>gi|110349759 NSL1, MIND kinetochore complex component isoform 1
[Homo sapiens]
Length = 281
Score = 33.5 bits (75), Expect = 0.41
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
Query: 213 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 260
+W +E + + INGQ D + E +D+ IVD T + P+K+ E
Sbjct: 77 QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
Query: 261 AVKSIKA 267
+K+IKA
Sbjct: 137 VIKTIKA 143
>gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
[Homo sapiens]
Length = 406
Score = 30.8 bits (68), Expect = 2.7
Identities = 32/114 (28%), Positives = 41/114 (35%), Gaps = 32/114 (28%)
Query: 41 LRLP---RETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSS 97
L+LP R P + G ++ E L G G +PP TL +L+D GS
Sbjct: 91 LQLPQWRRRRPPAPRDDGEEAAWEEESPGLSGGPGGSGAGSTVAEAPPGTLALLLDEGSK 150
Query: 98 NF---------------------------AVGAAPHPFLHRYYQRQLSSTYRDL 124
AVGA PH F R Y + L + YRDL
Sbjct: 151 QLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPH-FFDRSYDKGL-AWYRDL 202
>gi|195972903 zinc finger protein 385A isoform a [Homo sapiens]
Length = 386
Score = 30.0 bits (66), Expect = 4.6
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 17 LPAH--GTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKS 71
L AH GT+H L RSGLG RL T EPE P + +F + N++ S
Sbjct: 216 LEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNS 272
>gi|24308079 zinc finger protein 385A isoform c [Homo sapiens]
Length = 366
Score = 30.0 bits (66), Expect = 4.6
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 17 LPAH--GTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKS 71
L AH GT+H L RSGLG RL T EPE P + +F + N++ S
Sbjct: 196 LEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNS 252
>gi|44890065 hypothetical protein LOC6936 [Homo sapiens]
Length = 781
Score = 29.6 bits (65), Expect = 5.9
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 36 GAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQG 74
GAP L +P +EEP G R + +RG G+G
Sbjct: 30 GAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRG 68
>gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens]
Length = 497
Score = 29.6 bits (65), Expect = 5.9
Identities = 11/40 (27%), Positives = 22/40 (55%)
Query: 279 WLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITIL 318
++ L+ W TPW ++ +IS+ ++G V Q + +L
Sbjct: 99 FVAANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVL 138
>gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo
sapiens]
Length = 588
Score = 29.3 bits (64), Expect = 7.8
Identities = 23/89 (25%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 23 QHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVG 82
+HG + LR G G PLG+ + E +G V + G E G
Sbjct: 198 KHGGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVLAL----ADDGASVLFEAAGG 253
Query: 83 SPPQTLNILVDTGSSNFAVGAAPHPFLHR 111
P +++L++ G S A H +HR
Sbjct: 254 GNPDCISLLLEYGGSGNVPNRAGHLPIHR 282
>gi|40255133 hypothetical protein LOC222256 [Homo sapiens]
Length = 885
Score = 29.3 bits (64), Expect = 7.8
Identities = 17/57 (29%), Positives = 26/57 (45%)
Query: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVP 131
Y + + S + LV+TG+ ++ PHP + TY+ LRK VY P
Sbjct: 651 YVTDDNLMSDRKKAEALVETGTVTLSIKVIPHPTTIITTTPRPRVTYQVLRKNVYSP 707
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 29.3 bits (64), Expect = 7.8
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 173 GAGFPLNQSEVLASVGGSMI----IGGIDHSLYTGSLWYTPIRREWYYEVII 220
GAG N+ V++ G S + + GI + LY LW T I +W Y++ +
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGI-YLLYLQDLWTTVIDMKWRYKLTL 69
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 29.3 bits (64), Expect = 7.8
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 173 GAGFPLNQSEVLASVGGSMI----IGGIDHSLYTGSLWYTPIRREWYYEVII 220
GAG N+ V++ G S + + GI + LY LW T I +W Y++ +
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGI-YLLYLQDLWTTVIDMKWRYKLTL 69
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 29.3 bits (64), Expect = 7.8
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 173 GAGFPLNQSEVLASVGGSMI----IGGIDHSLYTGSLWYTPIRREWYYEVII 220
GAG N+ V++ G S + + GI + LY LW T I +W Y++ +
Sbjct: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGI-YLLYLQDLWTTVIDMKWRYKLTL 69
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,920,899
Number of Sequences: 37866
Number of extensions: 827912
Number of successful extensions: 1837
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1780
Number of HSP's gapped (non-prelim): 49
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.