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Search of human proteins with 21040279
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
(99 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 210 2e-55
gi|83582802 beta-defensin 128 [Homo sapiens] 62 1e-10
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens] 44 4e-05
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens] 44 4e-05
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens] 44 4e-05
gi|16905373 beta-defensin 118 [Homo sapiens] 43 5e-05
gi|82734223 beta-defensin 124 [Homo sapiens] 40 4e-04
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 39 7e-04
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 38 0.002
gi|58865339 defensin, beta 121 [Homo sapiens] 37 0.003
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens] 37 0.003
gi|116517226 beta-defensin 135 [Homo sapiens] 35 0.013
gi|23503331 defensin, beta 123 precursor [Homo sapiens] 35 0.013
gi|83582800 beta-defensin 116 [Homo sapiens] 34 0.022
gi|103485139 defensin, beta 104A precursor [Homo sapiens] 32 0.14
gi|103485137 defensin, beta 104B precursor [Homo sapiens] 32 0.14
gi|22748611 defensin, beta 106A precursor [Homo sapiens] 31 0.19
gi|103485143 defensin, beta 106B precursor [Homo sapiens] 31 0.19
gi|46409558 beta-defensin 32 precursor [Homo sapiens] 30 0.41
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens] 28 1.2
gi|22748617 defensin, beta 105A precursor [Homo sapiens] 28 1.2
gi|103485141 defensin, beta 105B precursor [Homo sapiens] 28 1.2
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 28 1.6
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 28 1.6
gi|83582798 beta-defensin 115 [Homo sapiens] 28 1.6
gi|18250304 beta defensin 129 precursor [Homo sapiens] 28 1.6
gi|4501989 alpha-fetoprotein precursor [Homo sapiens] 28 2.0
gi|67763814 death-inducing-protein [Homo sapiens] 28 2.0
gi|50344744 beta-defensin 108B [Homo sapiens] 27 3.5
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 27 3.5
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 210 bits (534), Expect = 2e-55
Identities = 99/99 (100%), Positives = 99/99 (100%)
Query: 1 MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKEL 60
MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKEL
Sbjct: 1 MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKEL 60
Query: 61 EACKKITKPPRPKPATLALTLQDYVTIIENFPSLKTQST 99
EACKKITKPPRPKPATLALTLQDYVTIIENFPSLKTQST
Sbjct: 61 EACKKITKPPRPKPATLALTLQDYVTIIENFPSLKTQST 99
>gi|83582802 beta-defensin 128 [Homo sapiens]
Length = 93
Score = 62.0 bits (149), Expect = 1e-10
Identities = 35/87 (40%), Positives = 52/87 (59%), Gaps = 2/87 (2%)
Query: 1 MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKEL 60
M LF+++ ILLF+ T +LKKC+N V G+CRK C+V E E C +G+ CC N +E
Sbjct: 1 MKLFLVLIILLFEVLTDGARLKKCFNK-VTGYCRKKCKVGERYEIGCLSGKLCCANDEEE 59
Query: 61 EACKKITKPPRPKPATLALTLQDYVTI 87
+ KP + L++ LQDY+ +
Sbjct: 60 KKHVSFKKPHQHSGEKLSV-LQDYIIL 85
>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 43.5 bits (101), Expect = 4e-05
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 16 TVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCL 55
+V K CW ++GHCRK C+ E + C+NG YCC+
Sbjct: 10 SVCRSQKSCW--IIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 43.5 bits (101), Expect = 4e-05
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 16 TVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCL 55
+V K CW ++GHCRK C+ E + C+NG YCC+
Sbjct: 10 SVCRSQKSCW--IIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 43.5 bits (101), Expect = 4e-05
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 16 TVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCL 55
+V K CW ++GHCRK C+ E + C+NG YCC+
Sbjct: 10 SVCRSQKSCW--IIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|16905373 beta-defensin 118 [Homo sapiens]
Length = 123
Score = 43.1 bits (100), Expect = 5e-05
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 22 KKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPPRPKPATLALTL 81
KKCWN GHCRK C+ E + C+N R CC+ E T P +T + +
Sbjct: 25 KKCWNR--SGHCRKQCKDGEAVKDTCKNLRACCIPSNEDHRRVPATSPTPLSDSTPGI-I 81
Query: 82 QDYVTI 87
D +T+
Sbjct: 82 DDILTV 87
>gi|82734223 beta-defensin 124 [Homo sapiens]
Length = 71
Score = 40.0 bits (92), Expect = 4e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 3 LFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEA 62
LF++ ++L P+ + K+CW QG C+ C E LC + CCL+
Sbjct: 6 LFLVALLVLGHVPSGRSEFKRCWKG--QGACQTYCTRQETYMHLCPDASLCCLSY----- 58
Query: 63 CKKITKPPRPK 73
+ PP PK
Sbjct: 59 --ALKPPPVPK 67
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 39.3 bits (90), Expect = 7e-04
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 3 LFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEA 62
L II LL + + + +KCW N V GHCR+ C E LC N CC++I E
Sbjct: 6 LTFIICGLLTRVTKGSFEPQKCWKNNV-GHCRRRCLDTERYILLCRNKLSCCISIISHEY 64
Query: 63 CKKITKP 69
++ P
Sbjct: 65 TRRPAFP 71
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 38.1 bits (87), Expect = 0.002
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 5/56 (8%)
Query: 3 LFMIIAILL-FQKPTVT--EQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCL 55
L++ +AILL ++P ++ + +C N G CR C+ NE P C N + CCL
Sbjct: 4 LYLFLAILLAIEEPVISGKRHILRCMGN--SGICRASCKKNEQPYLYCRNCQSCCL 57
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 37.4 bits (85), Expect = 0.003
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 6/65 (9%)
Query: 3 LFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEA 62
L + + +LL Q V KCW G CR C+ +EV LC+ CC++ K +
Sbjct: 6 LLLTVTLLLAQVTPVM----KCWGK--SGRCRTTCKESEVYYILCKTEAKCCVDPKYVPV 59
Query: 63 CKKIT 67
K+T
Sbjct: 60 KPKLT 64
>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
Length = 88
Score = 37.4 bits (85), Expect = 0.003
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 7/54 (12%)
Query: 3 LFMIIAILL-FQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCL 55
L++ +AILL ++P ++ + CW + GHCR +C+ E C N + CC+
Sbjct: 4 LYLFLAILLAIEEPVISVE---CW---MDGHCRLLCKDGEDSIIRCRNRKRCCV 51
>gi|116517226 beta-defensin 135 [Homo sapiens]
Length = 77
Score = 35.0 bits (79), Expect = 0.013
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%)
Query: 3 LFMIIAILLFQKPT--------VTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCC 54
L +++ LLF P + + CW +QG CR C NE LC+ CC
Sbjct: 8 LALVVLNLLFYVPPGRSGPNVYIQKIFASCWR--LQGTCRPKCLKNEQYRILCDTIHLCC 65
Query: 55 LNIKEL 60
+N K L
Sbjct: 66 VNPKYL 71
>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
Length = 67
Score = 35.0 bits (79), Expect = 0.013
Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 3 LFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIK 58
L + + +LL ++CWN Y G CR C E C N + CC+ K
Sbjct: 4 LLLTLTVLLLLSQLTPGGTQRCWNLY--GKCRYRCSKKERVYVYCINNKMCCVKPK 57
>gi|83582800 beta-defensin 116 [Homo sapiens]
Length = 102
Score = 34.3 bits (77), Expect = 0.022
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 25 WN--NYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPPRPKPATLALT 80
WN QG CR CR E+ C N + CCL + K K + L++T
Sbjct: 37 WNPCELYQGMCRNACREYEIQYLTCPNDQKCCLKLSVKITSSKNVKEDYDSNSNLSVT 94
>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
Length = 72
Score = 31.6 bits (70), Expect = 0.14
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Query: 3 LFMIIAILLFQKPTVTEQLKK---CWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKE 59
L + I++LL+Q V + + C Y CRK CR E C N CCL K
Sbjct: 6 LLLAISLLLYQDLPVRSEFELDRIC--GYGTARCRKKCRSQEYRIGRCPNTYACCLR-KW 62
Query: 60 LEACKKITKP 69
E+ TKP
Sbjct: 63 DESLLNRTKP 72
>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
Length = 72
Score = 31.6 bits (70), Expect = 0.14
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Query: 3 LFMIIAILLFQKPTVTEQLKK---CWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKE 59
L + I++LL+Q V + + C Y CRK CR E C N CCL K
Sbjct: 6 LLLAISLLLYQDLPVRSEFELDRIC--GYGTARCRKKCRSQEYRIGRCPNTYACCLR-KW 62
Query: 60 LEACKKITKP 69
E+ TKP
Sbjct: 63 DESLLNRTKP 72
>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
Length = 65
Score = 31.2 bits (69), Expect = 0.19
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 6 IIAILLFQKPTVTEQL-KKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIK 58
+ A+L F P +KC N ++G C+ C NE ALC+ CC I+
Sbjct: 7 LFAVLFFLTPAKNAFFDEKC--NKLKGTCKNNCGKNEELIALCQKSLKCCRTIQ 58
>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
Length = 65
Score = 31.2 bits (69), Expect = 0.19
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 6 IIAILLFQKPTVTEQL-KKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIK 58
+ A+L F P +KC N ++G C+ C NE ALC+ CC I+
Sbjct: 7 LFAVLFFLTPAKNAFFDEKC--NKLKGTCKNNCGKNEELIALCQKSLKCCRTIQ 58
>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
Length = 95
Score = 30.0 bits (66), Expect = 0.41
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 3 LFMIIAILLFQKPTVTEQL--KKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLN 56
L +++A L F + KC +N G+CR C E +C R CC++
Sbjct: 4 LLLVLAALGFLTQVIPASAGGSKCVSN-TPGYCRTCCHWGETALFMCNASRKCCIS 58
>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
Length = 73
Score = 28.5 bits (62), Expect = 1.2
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 6/57 (10%)
Query: 5 MIIAILLFQKPTVTEQLKKCWNNYVQ------GHCRKICRVNEVPEALCENGRYCCL 55
M IA+LLF Q+ + + G CR C E+ C N R CCL
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCL 57
>gi|22748617 defensin, beta 105A precursor [Homo sapiens]
Length = 78
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/25 (44%), Positives = 13/25 (52%)
Query: 30 QGHCRKICRVNEVPEALCENGRYCC 54
+G CRK C NE P+ C CC
Sbjct: 50 RGKCRKECLENEKPDGNCRLNFLCC 74
>gi|103485141 defensin, beta 105B precursor [Homo sapiens]
Length = 78
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/25 (44%), Positives = 13/25 (52%)
Query: 30 QGHCRKICRVNEVPEALCENGRYCC 54
+G CRK C NE P+ C CC
Sbjct: 50 RGKCRKECLENEKPDGNCRLNFLCC 74
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 28.1 bits (61), Expect = 1.6
Identities = 11/25 (44%), Positives = 12/25 (48%)
Query: 31 GHCRKICRVNEVPEALCENGRYCCL 55
G CR C E+ C N R CCL
Sbjct: 43 GSCRDFCLETEIHVGRCLNSRPCCL 67
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 28.1 bits (61), Expect = 1.6
Identities = 11/25 (44%), Positives = 12/25 (48%)
Query: 31 GHCRKICRVNEVPEALCENGRYCCL 55
G CR C E+ C N R CCL
Sbjct: 43 GSCRDFCLETEIHVGRCLNSRPCCL 67
>gi|83582798 beta-defensin 115 [Homo sapiens]
Length = 88
Score = 28.1 bits (61), Expect = 1.6
Identities = 11/55 (20%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 1 MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCL 55
+ + ++ +++ + +++C+ Y G CRK C+ E + C CC+
Sbjct: 15 LSVLALVVLVVLAQTAPDGWIRRCY--YGTGRCRKSCKEIERKKEKCGEKHICCV 67
>gi|18250304 beta defensin 129 precursor [Homo sapiens]
Length = 183
Score = 28.1 bits (61), Expect = 1.6
Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 16/109 (14%)
Query: 3 LFMIIAILLFQKPTVTE--QLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKEL 60
LF I A L+ Q TE L++C G CR C V+E C+ + CC+ K +
Sbjct: 4 LFPIFASLMLQYQVNTEFIGLRRCLMGL--GRCRDHCNVDEKEIQKCKM-KKCCVGPKVV 60
Query: 61 EACKKITKPPRP-----------KPATLALTLQDYVTIIENFPSLKTQS 98
+ K + P KPA + + I+ P +K+ S
Sbjct: 61 KLIKNYLQYGTPNVLNEDVQEMLKPAKNSSAVIQRKHILSVLPQIKSTS 109
>gi|4501989 alpha-fetoprotein precursor [Homo sapiens]
Length = 609
Score = 27.7 bits (60), Expect = 2.0
Identities = 19/77 (24%), Positives = 29/77 (37%), Gaps = 8/77 (10%)
Query: 8 AILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPE--------ALCENGRYCCLNIKE 59
A+ +KPT EQ C N + ++C E+ E + E GR+ C +
Sbjct: 70 ALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHK 129
Query: 60 LEACKKITKPPRPKPAT 76
I P+P T
Sbjct: 130 KPTPASIPLFQVPEPVT 146
>gi|67763814 death-inducing-protein [Homo sapiens]
Length = 578
Score = 27.7 bits (60), Expect = 2.0
Identities = 11/16 (68%), Positives = 12/16 (75%)
Query: 40 NEVPEALCENGRYCCL 55
NE P A+CENG CCL
Sbjct: 456 NERPLAVCENGWRCCL 471
>gi|50344744 beta-defensin 108B [Homo sapiens]
Length = 73
Score = 26.9 bits (58), Expect = 3.5
Identities = 17/57 (29%), Positives = 23/57 (40%), Gaps = 6/57 (10%)
Query: 5 MIIAILLFQKPTVTEQLKKCWNNYVQ------GHCRKICRVNEVPEALCENGRYCCL 55
M IA+LLF Q+ + + G CR C E+ C N + CCL
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCCL 57
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 26.9 bits (58), Expect = 3.5
Identities = 14/56 (25%), Positives = 23/56 (41%), Gaps = 4/56 (7%)
Query: 30 QGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPPRPKPATLALTLQDYV 85
Q C + C ++ C CC+N+ L +C P P T A + + +V
Sbjct: 46 QSTCERECSRDQD----CAAAEKCCINVCGLHSCVAARFPGSPAAPTTAASCEGFV 97
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,446,666
Number of Sequences: 37866
Number of extensions: 200254
Number of successful extensions: 510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 476
Number of HSP's gapped (non-prelim): 39
length of query: 99
length of database: 18,247,518
effective HSP length: 70
effective length of query: 29
effective length of database: 15,596,898
effective search space: 452310042
effective search space used: 452310042
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.