Guide to the Human Genome
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Name: AFP Sequence: fasta or formatted (609aa) NCBI GI: 4501989
Description:

alpha-fetoprotein precursor

Referenced in:

Proteins Measured in Common Diagnostic Tests
Liver
Nuclear Receptors

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         50           2
 C cysteine            5.3         32           2
 D aspartate           3.8         23           2
 E glutamate           9.7         59           3
 F phenylalanine       5.3         32           2
 G glycine             4.3         26           1
 H histidine           2.6         16           1
 I isoleucine          5.6         34           3
 K lysine              6.9         42           2
 L leucine             9.9         60           2
 M methionine          1.5          9           1
 N asparagine          3.3         20           1
 P proline             3.4         21           2
 Q glutamine           6.6         40           2
 R arginine            3.6         22           2
 S serine              6.2         38           2
 T threonine           5.9         36           2
 V valine              4.9         30           2
 W tryptophan          0.3          2           1
 Y tyrosine            2.8         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   alpha-fetoprotein precursor 
ALB                   0.392   albumin preproprotein 
AFM                   0.376   afamin precursor 
GC                    0.067   vitamin D-binding protein precursor 
LOC100294358          0.007   PREDICTED: hypothetical protein 
TLN1                  0.006   talin 1 
FRMD3                 0.004   FERM domain containing 3 
ATF3                  0.004   activating transcription factor 3 isoform 1 
ATF3                  0.004   activating transcription factor 3 isoform 1 
PCDHGB4               0.004   protocadherin gamma subfamily B, 4 isoform 2 precurs...
PCDHGB4               0.004   protocadherin gamma subfamily B, 4 isoform 1 precurs...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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