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Search of human proteins with 209571555
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209571555 von Willebrand factor D and EGF domains [Homo
sapiens]
(1590 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 3396 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 194 7e-49
gi|122937283 6720455I24Rik homolog [Homo sapiens] 191 6e-48
gi|24041035 notch 2 preproprotein [Homo sapiens] 187 7e-47
gi|55770876 notch4 preproprotein [Homo sapiens] 185 3e-46
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens] 182 2e-45
gi|153946395 tenascin C precursor [Homo sapiens] 180 9e-45
gi|134244285 Notch homolog 3 [Homo sapiens] 179 2e-44
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 172 2e-42
gi|4557679 jagged 1 precursor [Homo sapiens] 167 6e-41
gi|110735443 delta-like 1 [Homo sapiens] 164 8e-40
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 160 9e-39
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 156 1e-37
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 153 1e-36
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 152 3e-36
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 149 2e-35
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 148 4e-35
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 148 4e-35
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 148 4e-35
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 145 4e-34
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 142 2e-33
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 142 2e-33
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 139 3e-32
gi|93102379 low density lipoprotein-related protein 1B precursor... 138 4e-32
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 135 2e-31
gi|148886654 polydom [Homo sapiens] 131 5e-30
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 131 6e-30
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 127 7e-29
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 125 4e-28
gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens] 123 2e-27
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 3396 bits (8806), Expect = 0.0
Identities = 1590/1590 (100%), Positives = 1590/1590 (100%)
Query: 1 MPGGACVLVIALMFLAWGEAQECSPGGHQFLRSPYRSVRFDSWHLQQSAVQDLICDHSLS 60
MPGGACVLVIALMFLAWGEAQECSPGGHQFLRSPYRSVRFDSWHLQQSAVQDLICDHSLS
Sbjct: 1 MPGGACVLVIALMFLAWGEAQECSPGGHQFLRSPYRSVRFDSWHLQQSAVQDLICDHSLS 60
Query: 61 PGWYRFLILDRPAEMPTKCVEMNHCGTQAPIWLSLRDSETLPSPGEIKQLTACATWQFLF 120
PGWYRFLILDRPAEMPTKCVEMNHCGTQAPIWLSLRDSETLPSPGEIKQLTACATWQFLF
Sbjct: 61 PGWYRFLILDRPAEMPTKCVEMNHCGTQAPIWLSLRDSETLPSPGEIKQLTACATWQFLF 120
Query: 121 STTKDCCLFQIPVSVRNCGNFSVYLLQPTQGCMGYCAEAISDARLHPCGSDETETGGDCV 180
STTKDCCLFQIPVSVRNCGNFSVYLLQPTQGCMGYCAEAISDARLHPCGSDETETGGDCV
Sbjct: 121 STTKDCCLFQIPVSVRNCGNFSVYLLQPTQGCMGYCAEAISDARLHPCGSDETETGGDCV 180
Query: 181 RQLAASLPPPPAGRPEVLVELIESRLFCRCSFDVPATKNSVGFHIAWSRLSSQEVKEELT 240
RQLAASLPPPPAGRPEVLVELIESRLFCRCSFDVPATKNSVGFHIAWSRLSSQEVKEELT
Sbjct: 181 RQLAASLPPPPAGRPEVLVELIESRLFCRCSFDVPATKNSVGFHIAWSRLSSQEVKEELT 240
Query: 241 QETTVQAFSLLELDGINLRLGDRIFCSASVFFLENPHVQSVAIESQEFFAGFKLQPELST 300
QETTVQAFSLLELDGINLRLGDRIFCSASVFFLENPHVQSVAIESQEFFAGFKLQPELST
Sbjct: 241 QETTVQAFSLLELDGINLRLGDRIFCSASVFFLENPHVQSVAIESQEFFAGFKLQPELST 300
Query: 301 ISEDGKEYYLRIESTVPIICSEFSELDQECKISLKLKTIGQGREHLGLNLALSSCHVDLL 360
ISEDGKEYYLRIESTVPIICSEFSELDQECKISLKLKTIGQGREHLGLNLALSSCHVDLL
Sbjct: 301 ISEDGKEYYLRIESTVPIICSEFSELDQECKISLKLKTIGQGREHLGLNLALSSCHVDLL 360
Query: 361 QTSSCANGTCSHTFVYYTAVTDFSRDGDRVSNIVVQPIVNEDFLWNNYIPDSIQIKVKDV 420
QTSSCANGTCSHTFVYYTAVTDFSRDGDRVSNIVVQPIVNEDFLWNNYIPDSIQIKVKDV
Sbjct: 361 QTSSCANGTCSHTFVYYTAVTDFSRDGDRVSNIVVQPIVNEDFLWNNYIPDSIQIKVKDV 420
Query: 421 PTAYCYTFTDPHIITFDGRVYDNFKTGTFVLYKSMSRDFEVHVRQWDCRSLHYPVSCNCG 480
PTAYCYTFTDPHIITFDGRVYDNFKTGTFVLYKSMSRDFEVHVRQWDCRSLHYPVSCNCG
Sbjct: 421 PTAYCYTFTDPHIITFDGRVYDNFKTGTFVLYKSMSRDFEVHVRQWDCRSLHYPVSCNCG 480
Query: 481 FVAQEGGDIVTFDMCNGQLRESQPYLFIKSQDVTRNIKISESYLGRKVTIWFSSGAFIRA 540
FVAQEGGDIVTFDMCNGQLRESQPYLFIKSQDVTRNIKISESYLGRKVTIWFSSGAFIRA
Sbjct: 481 FVAQEGGDIVTFDMCNGQLRESQPYLFIKSQDVTRNIKISESYLGRKVTIWFSSGAFIRA 540
Query: 541 DLGEWGMSLTIRAPSVDYRNTLGLCGTFDENPENDFHDKNGMQIDQNFNNYVAFINEWRI 600
DLGEWGMSLTIRAPSVDYRNTLGLCGTFDENPENDFHDKNGMQIDQNFNNYVAFINEWRI
Sbjct: 541 DLGEWGMSLTIRAPSVDYRNTLGLCGTFDENPENDFHDKNGMQIDQNFNNYVAFINEWRI 600
Query: 601 LPGKSMSDTLPVSMTSPGKPSYCSCSLDTAAYPSSEDLDSVSRSEIALGCKDLNHVSLSS 660
LPGKSMSDTLPVSMTSPGKPSYCSCSLDTAAYPSSEDLDSVSRSEIALGCKDLNHVSLSS
Sbjct: 601 LPGKSMSDTLPVSMTSPGKPSYCSCSLDTAAYPSSEDLDSVSRSEIALGCKDLNHVSLSS 660
Query: 661 LIPELDVTSEYINSDTLVREINKHTSPEEYNLNLFLQEKKHINLTKLGLNVQKHPGNEKE 720
LIPELDVTSEYINSDTLVREINKHTSPEEYNLNLFLQEKKHINLTKLGLNVQKHPGNEKE
Sbjct: 661 LIPELDVTSEYINSDTLVREINKHTSPEEYNLNLFLQEKKHINLTKLGLNVQKHPGNEKE 720
Query: 721 DSLQYLANKKYTQGRGSHSQEMRYNRQNRWKRQNFHEFPPLFAFPSLSQTDLEELTYFFP 780
DSLQYLANKKYTQGRGSHSQEMRYNRQNRWKRQNFHEFPPLFAFPSLSQTDLEELTYFFP
Sbjct: 721 DSLQYLANKKYTQGRGSHSQEMRYNRQNRWKRQNFHEFPPLFAFPSLSQTDLEELTYFFP 780
Query: 781 EDHAEDVQQEFFPSWPTPSGLTEYSTLTLCQETLANSSIGRLCLAFLGKRLDSVIEMCVK 840
EDHAEDVQQEFFPSWPTPSGLTEYSTLTLCQETLANSSIGRLCLAFLGKRLDSVIEMCVK
Sbjct: 781 EDHAEDVQQEFFPSWPTPSGLTEYSTLTLCQETLANSSIGRLCLAFLGKRLDSVIEMCVK 840
Query: 841 DVLLKDDLSWAEAGVALLENECEKRIVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQC 900
DVLLKDDLSWAEAGVALLENECEKRIVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQC
Sbjct: 841 DVLLKDDLSWAEAGVALLENECEKRIVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQC 900
Query: 901 MEWGCACSPSFSSYDCSDSYDKAPEITELGNAGFCDVQKYNCMMVRVFGKGFKELPSIKC 960
MEWGCACSPSFSSYDCSDSYDKAPEITELGNAGFCDVQKYNCMMVRVFGKGFKELPSIKC
Sbjct: 901 MEWGCACSPSFSSYDCSDSYDKAPEITELGNAGFCDVQKYNCMMVRVFGKGFKELPSIKC 960
Query: 961 EVTKLQYNSSEWMPGEPIYTQTVFHNSRAVDCQLPTDVQQFDTMDLVGGKPTGKWQLKVS 1020
EVTKLQYNSSEWMPGEPIYTQTVFHNSRAVDCQLPTDVQQFDTMDLVGGKPTGKWQLKVS
Sbjct: 961 EVTKLQYNSSEWMPGEPIYTQTVFHNSRAVDCQLPTDVQQFDTMDLVGGKPTGKWQLKVS 1020
Query: 1021 NDGYKFSNPKITVIYDGACQVCGLYKNDSCTIKENVCIIDGLCYVEGDKNPTSPCLICRP 1080
NDGYKFSNPKITVIYDGACQVCGLYKNDSCTIKENVCIIDGLCYVEGDKNPTSPCLICRP
Sbjct: 1021 NDGYKFSNPKITVIYDGACQVCGLYKNDSCTIKENVCIIDGLCYVEGDKNPTSPCLICRP 1080
Query: 1081 KISRFTWSFLENNQPPVIQALQDKLQTFYGENFEYQFVAFDPEGSDIHFTLDSGPEGASV 1140
KISRFTWSFLENNQPPVIQALQDKLQTFYGENFEYQFVAFDPEGSDIHFTLDSGPEGASV
Sbjct: 1081 KISRFTWSFLENNQPPVIQALQDKLQTFYGENFEYQFVAFDPEGSDIHFTLDSGPEGASV 1140
Query: 1141 SSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSG 1200
SSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSG
Sbjct: 1141 SSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSG 1200
Query: 1201 VYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQFVNQFTTQ 1260
VYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQFVNQFTTQ
Sbjct: 1201 VYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQFVNQFTTQ 1260
Query: 1261 TVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGY 1320
TVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGY
Sbjct: 1261 TVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGY 1320
Query: 1321 IGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTC 1380
IGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTC
Sbjct: 1321 IGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTC 1380
Query: 1381 PYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN 1440
PYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN
Sbjct: 1381 PYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN 1440
Query: 1441 TCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKC 1500
TCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKC
Sbjct: 1441 TCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKC 1500
Query: 1501 VGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLY 1560
VGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLY
Sbjct: 1501 VGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLY 1560
Query: 1561 GGRCIFPNVCSCRTEYSGVKCEKKIQIRRH 1590
GGRCIFPNVCSCRTEYSGVKCEKKIQIRRH
Sbjct: 1561 GGRCIFPNVCSCRTEYSGVKCEKKIQIRRH 1590
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 194 bits (492), Expect = 7e-49
Identities = 144/470 (30%), Positives = 193/470 (41%), Gaps = 83/470 (17%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCD 1242
C NGG+C G + C C G+H C +++ C SNPC G+ + Y CD
Sbjct: 687 CHNGGTC------EDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCD 740
Query: 1243 CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQG-----RKRHVKPTSGNAFTI 1297
C P +N + S+ VN G R+ P
Sbjct: 741 CDPGWSGTNCDINNNECE------SNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE 794
Query: 1298 C-KYPCGKSREC---VAPNICKCKPGYIGSNCQTAL--CDPD-CKNHGKCIKPN-----I 1345
C PC C VA C C Y G+ C+ L C P C+N G+C +
Sbjct: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFS 854
Query: 1346 CQCLPGHGGATCD---EEHCNPPCQHGGTCL---AGNLCTCPYGFVGPRCETMV--CNRH 1397
C C G G TC+ E PC+HG +C G C C G+ G CET + C +
Sbjct: 855 CVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPN 914
Query: 1398 -CENGGQC---LTPDICQCKPGWYGPTCSTAL----CDPVCLNGGSCNK---PNTCLCPN 1446
C NGG C + C C PG+ G C + DP C NG +C TC CP
Sbjct: 915 PCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDP-CRNGANCTDCVDSYTCTCPA 973
Query: 1447 GFFGEHCQN---AFCHPPCKNGGHC---MRNNVCVCREGYTGRRFQKSI--CD-PTCMNG 1497
GF G HC+N C NGG C + + C+C G+TG Q + CD C++G
Sbjct: 974 GFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG 1033
Query: 1498 GKC---VGPSTCSCPSGWSGKRCNTPI--C-LQKCKNGGECIAPSI---CHCPSSWEGVR 1548
G C G C+CP G++G C + C CKNGG+C C CPS W G+
Sbjct: 1034 GTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLY 1093
Query: 1549 CQIPICNPK-------------CLYGGRCI---FPNVCSCRTEYSGVKCE 1582
C +P + + C +GG C+ + C C+ Y+G CE
Sbjct: 1094 CDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143
Score = 184 bits (467), Expect = 6e-46
Identities = 155/495 (31%), Positives = 205/495 (41%), Gaps = 121/495 (24%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISG-FHSYSC 1241
C NGGSC G C CLPGF G+ CE DI+ C S+PC G+ + SY+C
Sbjct: 916 CHNGGSCTD------GINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 969
Query: 1242 DCP------------PELKVETQF--------VNQFTTQT---VVLTRSDKSVNKEEDDK 1278
CP P+ + F +N FT + VN+ +
Sbjct: 970 TCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQP 1029
Query: 1279 NAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL--CDPD-CK 1335
G C+ CG R C C GY G NCQ + CD CK
Sbjct: 1030 CLHGGT-------------CQDGCGSYR-------CTCPQGYTGPNCQNLVHWCDSSPCK 1069
Query: 1336 NHGKCIKPNI---CQCLPGHGGATCDEEHCNPP-------------CQHGGTCL-AGNL- 1377
N GKC + + C+C G G CD + CQHGG C+ AGN
Sbjct: 1070 NGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH 1129
Query: 1378 -CTCPYGFVGPRCETMV--CNRH-CENGGQC---LTPDICQCKPGWYGPTCSTALCDPV- 1429
C C G+ G CE +V C+ C+NG C L C+C G++G CS + + +
Sbjct: 1130 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLS 1189
Query: 1430 --CLNGGSC-NKPNT--CLCPNGFFGEHCQNAF--CHPP---------CKNGGHCMRN-- 1471
C NGG+C + PNT C CP G G HC+ C+PP C N G C+
Sbjct: 1190 HPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVG 1249
Query: 1472 -NVCVCREGYTGRRFQKSI-------CDPT-CMNGGKCVGPSTCSCPSGWSGKRCNTPI- 1521
C C G+ G R + + CD N + V C C +G +G+RC + I
Sbjct: 1250 GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN 1309
Query: 1522 -CLQK-CKNGGECIAPS------ICHCPSSWEGVRCQ--IPICNP-KCLYGGRCIF---P 1567
C K CKNGG C S IC CP+ +EG C+ C +CL GG CI
Sbjct: 1310 GCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRS 1369
Query: 1568 NVCSCRTEYSGVKCE 1582
C C ++G +C+
Sbjct: 1370 PTCLCLGPFTGPECQ 1384
Score = 177 bits (450), Expect = 6e-44
Identities = 145/485 (29%), Positives = 194/485 (40%), Gaps = 113/485 (23%)
Query: 1173 TIEVTVKSC---DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-G 1228
T EV + C C +G SC + G Y C C G+ G CE DI C+ NPC
Sbjct: 865 TCEVDINECVLSPCRHGASCQNTH------GGYRCHCQAGYSGRNCETDIDDCRPNPCHN 918
Query: 1229 LGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVK 1288
GS G ++ CDC P + T ++ +N+ D G
Sbjct: 919 GGSCTDGINTAFCDCLPGFRG---------------TFCEEDINECASDPCRNG------ 957
Query: 1289 PTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCD---PDCKNHGKC---IK 1342
+CV C C G+ G +C+ D C N G C I
Sbjct: 958 --------------ANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN 1003
Query: 1343 PNICQCLPGHGGATC--DEEHCNP-PCQHGGTCLAG---NLCTCPYGFVGPRCETMV--C 1394
C C PG G+ C D C+ PC HGGTC G CTCP G+ GP C+ +V C
Sbjct: 1004 SFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWC 1063
Query: 1395 NRH-CENGGQCL---TPDICQCKPGWYGPTCS--TALCDP-----------VCLNGGSC- 1436
+ C+NGG+C T C+C GW G C + C+ +C +GG C
Sbjct: 1064 DSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCV 1123
Query: 1437 --NKPNTCLCPNGFFGEHCQNAF--CHP-PCKNGGHC---MRNNVCVCREGYTGRRFQKS 1488
+ C C G+ G +C++ C P PC+NG C + C C GY G +
Sbjct: 1124 DAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE 1183
Query: 1489 ICD---PTCMNGGKCVG-PST--CSCPSGWSGKRC-------NTPIC----LQKCKNGGE 1531
I + C NGG C+ P+T CSCP G G C N P+ KC N G
Sbjct: 1184 IDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGT 1243
Query: 1532 CI---APSICHCPSSWEGVRCQIPI----CNPKCLYGGRCIFPNV----CSCRTEYSGVK 1580
C+ C CP + G RC+ + NP G + V C CR ++G +
Sbjct: 1244 CVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRR 1303
Query: 1581 CEKKI 1585
CE I
Sbjct: 1304 CESVI 1308
Score = 174 bits (440), Expect = 8e-43
Identities = 146/464 (31%), Positives = 185/464 (39%), Gaps = 72/464 (15%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C NGG+C G + C CLPGF G CE +I C N C G+ + G ++Y+C
Sbjct: 227 CQNGGTCRPT-----GDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNC 281
Query: 1242 DCPPELKVETQFVNQFTTQTV-VLTRSDKSVNKEEDDKNAQGRKRHV-------KPTSGN 1293
CPPE + Q+ T+ V + N G V + S N
Sbjct: 282 RCPPE------WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSEN 335
Query: 1294 AFTICKYPCGKSREC---VAPNICKCKPGYIGSNCQ-TALCDPDCKNHGKCIKPN----- 1344
C C VA C+C G G C C + N G N
Sbjct: 336 IDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGK 395
Query: 1345 -ICQCLPGHGGATC--DEEHCN---PPCQHGGTC---LAGNLCTCPYGFVGPRCETMV-- 1393
IC C G+ G C D + C+ PC+H G C L C C G+ GPRCE V
Sbjct: 396 AICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNE 455
Query: 1394 -CNRHCENGGQCLT---PDICQCKPGWYGPTC--STALC-DPVCLNGGSC-NKPN--TCL 1443
+ C+N CL C C PG+ G C +T C CL+ G C +K N C
Sbjct: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCE 515
Query: 1444 CPNGFFGEHCQ---NAFCHPPCKNGGHCM---RNNVCVCREGYTGRRFQKSI--CDPTCM 1495
CP GF G CQ + PCKNG C+ CVC EGYTG + I CDP
Sbjct: 516 CPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC 575
Query: 1496 NGGKC---VGPSTCSCPSGWSGKRCNTPI---CLQKCKNGGECIAPS---ICHCPSSWEG 1546
+ G C V TC C G++G C T I Q C++GG C +C C G
Sbjct: 576 HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG 635
Query: 1547 VRCQIPI--CNPKCLYGGRC---IFPNVCSCRTEYSGVKCEKKI 1585
C+I + C G C I C+C Y+G C I
Sbjct: 636 PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINI 679
Score = 174 bits (440), Expect = 8e-43
Identities = 139/508 (27%), Positives = 207/508 (40%), Gaps = 111/508 (21%)
Query: 1175 EVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYI 1233
E ++ + C + G C++ G + C CL G+ G CE+D++ C SNPC + +
Sbjct: 415 ECSLGANPCEHAGKCINTL------GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL 468
Query: 1234 SGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
+ C C P + VN + + + ++K + + + +G
Sbjct: 469 DQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ--------CECPTGF 520
Query: 1294 AFTICKY--------PCGKSRECV-APN--ICKCKPGYIGSNCQTAL--CDPDCKNHGKC 1340
+C+Y PC +C+ PN C C GY G++C+ + CDPD ++G C
Sbjct: 521 TGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSC 580
Query: 1341 ---IKPNICQCLPGHGGATCD---EEHCNPPCQHGGTCLAGN---LCTCPYGFVGPRCET 1391
+ C C PG+ G C+ E + PC+HGGTC + LC C G GP CE
Sbjct: 581 KDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI 640
Query: 1392 --------------------------------MVCN--------RHCENGGQC---LTPD 1408
+CN C NGG C +
Sbjct: 641 NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF 700
Query: 1409 ICQCKPGWYGPTCSTAL--CDP-VCLNGGSCNKPN--TCLCPNGFFGEHC--QNAFCHP- 1460
C+C G++ PTC + + C+ C++G + N C C G+ G +C N C
Sbjct: 701 TCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN 760
Query: 1461 PCKNGGHC---MRNNVCVCREGYTGRRFQKSI---CDPTCMNGGKC---VGPSTCSCPSG 1511
PC NGG C VC CREG++G Q +I C+N G C V C+C
Sbjct: 761 PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLP 820
Query: 1512 WSGKRCN---TPICLQKCKNGGEC-----IAPSICHCPSSWEGVRCQIPICN---PKCLY 1560
++G C P C+NGGEC C CP+ W+G C++ I C +
Sbjct: 821 YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRH 880
Query: 1561 GGRCIFPN---VCSCRTEYSGVKCEKKI 1585
G C + C C+ YSG CE I
Sbjct: 881 GASCQNTHGGYRCHCQAGYSGRNCETDI 908
Score = 162 bits (411), Expect = 2e-39
Identities = 140/504 (27%), Positives = 194/504 (38%), Gaps = 143/504 (28%)
Query: 1180 SCDCLNGGSC-VSDRNFSPGSGVYLCVCLPGFHGSLCEVDI-SGCQSNPCGLGSY--ISG 1235
S C N G+C V DR G Y C C GF G LC + + C +NPC G +
Sbjct: 65 STPCKNAGTCHVVDRR---GVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT 121
Query: 1236 FHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAF 1295
Y C CPP S KS + + P + N
Sbjct: 122 LTEYKCRCPPGW-------------------SGKSCQQAD-------------PCASN-- 147
Query: 1296 TICKYPCGKSRECV---APNICKCKPGYIGSNCQTALCDPD-----CKNHGKC---IKPN 1344
PC +C+ A IC C P + G C+ + + C++ G C +
Sbjct: 148 -----PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSY 202
Query: 1345 ICQCLPGHGGATCDEEH--CNP-PCQHGGTCL-AGNL---CTCPYGFVGPRCETMV--C- 1394
C C H G C+ + C+P PCQ+GGTC G++ C C GF G CE + C
Sbjct: 203 RCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCP 262
Query: 1395 NRHCENGGQC---LTPDICQCKPGWYGPTCS-----TALCDPVCLNGGSCNKPN---TCL 1443
+C+NGG C + C+C P W G C+ L C NGG+C+ + C+
Sbjct: 263 GNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCV 322
Query: 1444 CPNGFFGEHC-------------QNAFCHP---------------------------PCK 1463
C NG+ GE C A CH PC
Sbjct: 323 CVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCN 382
Query: 1464 NGGHCMRNNV-----CVCREGYTGRRFQKSICDPT-----CMNGGKCV---GPSTCSCPS 1510
G +C N V C C GYTG + + + + C + GKC+ G C C
Sbjct: 383 EGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQ 442
Query: 1511 GWSGKRCNTPI--CLQK-CKNGGEC---IAPSICHCPSSWEGVRCQI---PICNPKCLYG 1561
G++G RC + C+ C+N C I C C +EGV C++ + CL+
Sbjct: 443 GYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHN 502
Query: 1562 GRC---IFPNVCSCRTEYSGVKCE 1582
GRC I C C T ++G C+
Sbjct: 503 GRCLDKINEFQCECPTGFTGHLCQ 526
Score = 160 bits (406), Expect = 7e-39
Identities = 138/502 (27%), Positives = 182/502 (36%), Gaps = 107/502 (21%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFH-SYSC 1241
C NGG+C Y C C PG+ G C+ C SNPC G F SY C
Sbjct: 111 CRNGGTCDLLTLTE-----YKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYIC 164
Query: 1242 DCPPELKVET--QFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICK 1299
CPP T Q VN+ Q L R + + E R H P + C
Sbjct: 165 HCPPSFHGPTCRQDVNE-CGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
Query: 1300 -YPCGKSREC----VAPNICKCKPGYIGSNCQTALCD---PDCKNHGKCI---------- 1341
PC C + C C PG+ G NC+ + D +CKN G C+
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
Query: 1342 ------------------KPNICQ----CLPGHGGATC------DEEHC--------NPP 1365
PN CQ C HGG C E C +
Sbjct: 284 PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA 343
Query: 1366 CQHGGTC---LAGNLCTCPYGFVGPRC--ETMVCNRHCENGGQCLT-----PDICQCKPG 1415
C HG TC +A C CP+G G C + C G C T IC C G
Sbjct: 344 CFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSG 403
Query: 1416 WYGPTCSTALCDPVCLNGGSCNKPNTCL---------CPNGFFGEHCQ---NAFCHPPCK 1463
+ GP CS + D L C C+ C G+ G C+ N PC+
Sbjct: 404 YTGPACSQDV-DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQ 462
Query: 1464 NGGHCM---RNNVCVCREGYTGRRFQ---KSICDPTCMNGGKC---VGPSTCSCPSGWSG 1514
N C+ C+C GY G + C++ G+C + C CP+G++G
Sbjct: 463 NDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTG 522
Query: 1515 KRCNTPI---CLQKCKNGGECI-APS--ICHCPSSWEGVRCQIPI--CNPKCLYGGRC-- 1564
C + CKNG +C+ P+ C C + G C++ I C+P + G C
Sbjct: 523 HLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKD 582
Query: 1565 -IFPNVCSCRTEYSGVKCEKKI 1585
+ C CR Y+G CE I
Sbjct: 583 GVATFTCLCRPGYTGHHCETNI 604
Score = 149 bits (375), Expect = 3e-35
Identities = 138/453 (30%), Positives = 178/453 (39%), Gaps = 101/453 (22%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYIS-GFHSYSC 1241
C NGG+CV G + C+C PGF GS C+ D++ C S PC G G SY C
Sbjct: 992 CFNGGTCVD------GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRC 1045
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
CP Q Q +V D S K + + SG C P
Sbjct: 1046 TCP-------QGYTGPNCQNLVHW-CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVP 1097
Query: 1302 ------------------CGKSRECV-APNI--CKCKPGYIGSNCQTAL--CDPD-CKNH 1337
C CV A N C+C+ GY GS C+ + C P C+N
Sbjct: 1098 SVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNG 1157
Query: 1338 GKC---IKPNICQCLPGHGGATCDEE--HC-NPPCQHGGTCLA---GNLCTCPYGFVGPR 1388
C + C+C+ G+ G C EE C + PCQ+GGTCL C+CP G G
Sbjct: 1158 ATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
Query: 1389 CETMV--CNR---------HCENGGQCLTPD---ICQCKPGWYGPTCSTALCDPVCLNGG 1434
CE V CN C N G C+ C C PG+ G C + + CL+
Sbjct: 1218 CEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNE--CLSN- 1274
Query: 1435 SCNKPNT-----------CLCPNGFFGEHCQ---NAFCHPPCKNGGHCM------RNNVC 1474
C+ T C C G G C+ N PCKNGG C R +C
Sbjct: 1275 PCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFIC 1334
Query: 1475 VCREGYTGRRFQ---KSICDPTCMNGGKCV-GPS--TCSCPSGWSGKRCNTPI---CL-- 1523
C G+ G + ++ C+NGG C+ GP TC C ++G C P CL
Sbjct: 1335 KCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGG 1394
Query: 1524 QKCKNGGECIAPSI-----CHCPSSWEGVRCQI 1551
C N G C S C CP+ + G+ C I
Sbjct: 1395 NPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427
Score = 145 bits (365), Expect = 4e-34
Identities = 105/347 (30%), Positives = 145/347 (41%), Gaps = 63/347 (18%)
Query: 1298 CKYP---CGKSRECVAPN---ICKCKPGYIGSNCQ--TALCDPDCKNHGKC-------IK 1342
C P C +C A N C C ++G CQ CKN G C +
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVA 83
Query: 1343 PNICQCLPGHGGATC----DEEHCNPPCQHGGTC----LAGNLCTCPYGFVGPRCETM-- 1392
C C G G C D PC++GGTC L C CP G+ G C+
Sbjct: 84 DYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP 143
Query: 1393 VCNRHCENGGQCLTPD---ICQCKPGWYGPTCSTALCD-----PVCLNGGSCNK---PNT 1441
+ C NGGQCL + IC C P ++GPTC + + +C +GG+C+
Sbjct: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYR 203
Query: 1442 CLCPNGFFGEHCQNAF--CHP-PCKNGGHCMR----NNVCVCREGYTGRRFQKSICD--- 1491
C+C G +C+ + C P PC+NGG C + C C G+TG+ +++I D
Sbjct: 204 CVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPG 263
Query: 1492 PTCMNGGKCV-GPST--CSCPSGWSGKRCNTPI-----CLQKCKNGGEC---IAPSICHC 1540
C NGG CV G +T C CP W+G+ C + C+NGG C C C
Sbjct: 264 NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC 323
Query: 1541 PSSWEGVRCQIPI---CNPKCLYGGRC---IFPNVCSCRTEYSGVKC 1581
+ W G C I + C +G C + C C +G+ C
Sbjct: 324 VNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
Score = 141 bits (356), Expect = 4e-33
Identities = 122/420 (29%), Positives = 164/420 (39%), Gaps = 94/420 (22%)
Query: 1178 VKSCD---CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYIS 1234
V CD CL+GG+C G G Y C C G+ G C+ + C S+PC G
Sbjct: 1022 VNECDSQPCLHGGTC------QDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCW 1075
Query: 1235 GFHS-YSCDCP----------PELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGR 1283
H+ Y C+CP P + E Q + V+ G
Sbjct: 1076 QTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD--------AGN 1127
Query: 1284 KRHVKPTSGNAFTICK--------YPCGKSREC---VAPNICKCKPGYIGSNCQTAL--- 1329
H + +G + C+ PC C + CKC GY G NC +
Sbjct: 1128 THHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDEC 1187
Query: 1330 CDPDCKNHGKCIK-PNI--CQCLPGHGGATCD--EEHCNPP---------CQHGGTC--- 1372
C+N G C+ PN C C G G C+ + CNPP C + GTC
Sbjct: 1188 LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQ 1247
Query: 1373 LAGNLCTCPYGFVGPRCETMV-------CN-RHCENGGQCLTPDICQCKPGWYGPTCSTA 1424
+ G CTCP GFVG RCE V C+ R +N Q + C+C+ G G C +
Sbjct: 1248 VGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESV 1307
Query: 1425 L--C-DPVCLNGGSCNKPNT------CLCPNGFFGEHCQN--AFCHP-PCKNGGHCM--- 1469
+ C C NGG+C + C CP GF G C+N C C NGG C+
Sbjct: 1308 INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGP 1367
Query: 1470 RNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCS-----------CPSGWSGKRCN 1518
R+ C+C +TG Q P C+ G C TC CP+ ++G C+
Sbjct: 1368 RSPTCLCLGPFTGPECQFPASSP-CLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCH 1426
Score = 134 bits (337), Expect = 7e-31
Identities = 104/348 (29%), Positives = 145/348 (41%), Gaps = 64/348 (18%)
Query: 1301 PCGKSREC-------VAPNICKCKPGYIGSNCQTALCDP----DCKNHGKC----IKPNI 1345
PC + C VA C C G+ G C T L + C+N G C +
Sbjct: 67 PCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYK 126
Query: 1346 CQCLPGHGGATCDEEH--CNPPCQHGGTCL---AGNLCTCPYGFVGPRCETMV--CNRH- 1397
C+C PG G +C + + PC +GG CL A +C CP F GP C V C +
Sbjct: 127 CRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKP 186
Query: 1398 --CENGGQC---LTPDICQCKPGWYGPTCSTAL--CDP-VCLNGGSC----NKPNTCLCP 1445
C +GG C + C C+ GP C C P C NGG+C + + C C
Sbjct: 187 GLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL 246
Query: 1446 NGFFGEHCQNAFCHPP---CKNGGHC---MRNNVCVCREGYTGRRFQKSICD-----PTC 1494
GF G++C+ P CKNGG C + C C +TG+ + + + C
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 1495 MNGGKC---VGPSTCSCPSGWSGKRCNTPI---CLQKCKNGGEC---IAPSICHCPSSWE 1545
NGG C G C C +GW+G+ C+ I C +G C +A C CP
Sbjct: 307 QNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRT 366
Query: 1546 GVRCQIP---ICNPKCLYGGRCIF-----PNVCSCRTEYSGVKCEKKI 1585
G+ C + I NP C G C +C+C + Y+G C + +
Sbjct: 367 GLLCHLNDACISNP-CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDV 413
Score = 133 bits (334), Expect = 2e-30
Identities = 104/309 (33%), Positives = 132/309 (42%), Gaps = 60/309 (19%)
Query: 1334 CKNHGKCIKPN---ICQCLPGHGGATCDEEH--CNPPCQHGGTC-------LAGNLCTCP 1381
C N GKC N C C G C + + + PC++ GTC +A C+C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
Query: 1382 YGFVGPRCETMVCN----RHCENGGQC----LTPDICQCKPGWYGPTCSTALCDPV---- 1429
GF GP C T + N C NGG C LT C+C PGW G +C A DP
Sbjct: 91 LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA--DPCASNP 148
Query: 1430 CLNGGSC---NKPNTCLCPNGFFGEHCQ---NAFCHPP--CKNGGHCMRNNV----CVCR 1477
C NGG C C CP F G C+ N P C++GG C N V CVCR
Sbjct: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC-HNEVGSYRCVCR 207
Query: 1478 EGYTGRRFQKSI--CDPT-CMNGGKC--VGPST--CSCPSGWSGKRC--NTPICL-QKCK 1527
+TG ++ C P+ C NGG C G T C+C G++G+ C N C CK
Sbjct: 208 ATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCK 267
Query: 1528 NGGEC---IAPSICHCPSSWEGVRC-----QIPICNPKCLYGGRCIFPN---VCSCRTEY 1576
NGG C + C CP W G C + + C GG C + C C +
Sbjct: 268 NGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGW 327
Query: 1577 SGVKCEKKI 1585
+G C + I
Sbjct: 328 TGEDCSENI 336
Score = 110 bits (275), Expect = 1e-23
Identities = 69/199 (34%), Positives = 86/199 (43%), Gaps = 35/199 (17%)
Query: 1418 GPTCSTALCDPVCLNGGSCNKPN---TCLCPNGFFGEHCQ--NAFCHPPCKNGGHC---- 1468
GP CS CLNGG C N C+C F G CQ N PCKN G C
Sbjct: 21 GPRCSQP--GETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVD 78
Query: 1469 ---MRNNVCVCREGYTG----RRFQKSICDPTCMNGGKC----VGPSTCSCPSGWSGKRC 1517
+ + C C G++G + C NGG C + C CP GWSGK C
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC 138
Query: 1518 N--TPICLQKCKNGGECI---APSICHCPSSWEGVRCQIPI--CNPK---CLYGGRC--- 1564
P C NGG+C+ A ICHCP S+ G C+ + C K C +GG C
Sbjct: 139 QQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNE 198
Query: 1565 IFPNVCSCRTEYSGVKCEK 1583
+ C CR ++G CE+
Sbjct: 199 VGSYRCVCRATHTGPNCER 217
Score = 82.4 bits (202), Expect = 3e-15
Identities = 108/427 (25%), Positives = 150/427 (35%), Gaps = 110/427 (25%)
Query: 1155 TQQITVRLN-DDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGS 1213
TQ + +N DDC+ ++ +S C N G+CV G Y C C PGF G
Sbjct: 1213 TQGVHCEINVDDCNPP----VDPVSRSPKCFNNGTCVDQ------VGGYSCTCPPGFVGE 1262
Query: 1214 LCEVDISGCQSNPC---GLGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKS 1270
CE D++ C SNPC G + + + + C+C
Sbjct: 1263 RCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC--------------------------- 1295
Query: 1271 VNKEEDDKNAQGRKRHVKPTSGNAFTICK-YPCGKSREC-VAPN-----ICKCKPGYIGS 1323
R H + CK PC C VA N ICKC G+ G+
Sbjct: 1296 ------------RAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGA 1343
Query: 1324 NCQ--TALCDP-DCKNHGKCI---KPNICQCLPGHGGATCDEEHCNP-----PCQHGGTC 1372
C+ C C N G CI + C CL G C +P PC + GTC
Sbjct: 1344 TCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTC 1403
Query: 1373 LAGN-----LCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQ--CKPGWYGPTCSTAL 1425
+ C CP F G C + + G+ + P + + C+ P C
Sbjct: 1404 EPTSESPFYRCLCPAKFNGLLCHILDYS-FGGGAGRDIPPPLIEEACEL----PECQEDA 1458
Query: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRF 1485
+ VC CN + C G+ G C F + P KN C ++ C + F
Sbjct: 1459 GNKVC--SLQCNN-HAC----GWDGGDCSLNF-NDPWKN---CTQSLQC-------WKYF 1500
Query: 1486 QKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCK---NGGECIAPSICHCPS 1542
CD C + G C G +CN P+ Q CK + G C
Sbjct: 1501 SDGHCDSQCNSAGCLFDGFDCQRAEG----QCN-PLYDQYCKDHFSDGHC-DQGCNSAEC 1554
Query: 1543 SWEGVRC 1549
W+G+ C
Sbjct: 1555 EWDGLDC 1561
Score = 37.0 bits (84), Expect = 0.15
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 8/59 (13%)
Query: 891 PNLCSGNGQCMEWG-----CACSPSFSSYDCSDSYDKAPEITELGNAGFC--DVQKYNC 942
P+ C G C G CAC P F+ +C ++ D P N G C V YNC
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPG-NNCKNGGACVDGVNTYNC 281
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 191 bits (484), Expect = 6e-48
Identities = 146/466 (31%), Positives = 192/466 (41%), Gaps = 98/466 (21%)
Query: 1167 DAETRV-----TIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISG 1221
DA+ RV T V + CLNGG C+ D G+ Y C CL GF G C +D++
Sbjct: 257 DAQVRVGGCGHTTSVCLALRPCLNGGKCIDD--CVTGNPSYTCSCLSGFTGRRCHLDVNE 314
Query: 1222 CQSNPCGLGSYIS-GFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNA 1280
C S PC G + G +S+ C CP T ++ D K
Sbjct: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTC----------------ETAQSPCDTKEC 358
Query: 1281 Q-GRKRHVKPTSGNAFTICKY-----------------PCGKSRECV---APNICKCKPG 1319
Q G + V+ +G+A +C+ PC CV C C
Sbjct: 359 QHGGQCQVE--NGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP 416
Query: 1320 YIGSNCQT-------ALCDPDCKNHGKCIKPN---ICQCLPGHGGATCDE---EHCNPPC 1366
+ G C+T A C N G C+ + +C+C G G C E + C C
Sbjct: 417 FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE--C 474
Query: 1367 QHGGTCLAGN--LCTCPYGFVGPRCE----TMVCNRH--CENGGQCLTPD---ICQCKPG 1415
++GG CL N LC CP GF G CE M CN + C +GG C+ +C C
Sbjct: 475 RNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD 534
Query: 1416 WYGPTCSTALCD-PVCLNGGSCNKPN---TCLCPNGFFGEHCQNAFCH----PPCKNGGH 1467
+ CD C NGGSC+ + TC CP GF G+HC+ A H PC+NGG
Sbjct: 535 HNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGT 594
Query: 1468 CMR---NNVCVCREGYTGRRFQ----KSICDPTCMNGGKC---VGPSTCSCPSGWSGKRC 1517
C C C +TGR + S C NGG C +G C CP G+SG+ C
Sbjct: 595 CKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHC 654
Query: 1518 N---TPICLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI-CNP 1556
+P C NGG C CHC + + G RCQ + C P
Sbjct: 655 EIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP 700
Score = 162 bits (411), Expect = 2e-39
Identities = 113/321 (35%), Positives = 145/321 (45%), Gaps = 52/321 (16%)
Query: 1314 CKCKPGYIGSNCQTAL--CD-PDCKNHGKCIKPN---ICQCLPGHGGATC--DEEHCNP- 1364
C+C G+ G C+TA CD +C++ G+C N +C C G+ GA C D + C+P
Sbjct: 335 CQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPD 394
Query: 1365 PCQHGGTC--LAGN-LCTCPYGFVGPRCET-------MVCNRHCENGGQCLTPD---ICQ 1411
PC +GG+C L GN C C F G RCET + C NGG C+ D +C+
Sbjct: 395 PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCE 454
Query: 1412 CKPGWYGPTCSTALCDPV-CLNGGSCNKPNT--CLCPNGFFGEHCQNAFCHPPCK----- 1463
C G+ G C + D C NGG C NT C CP GFFG C+ PC
Sbjct: 455 CPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQC 514
Query: 1464 -NGGHCMRNN---VCVCREGYTGRRFQKSICD-PTCMNGGKCVGPS---TCSCPSGWSGK 1515
+GG+CM + +CVC + S CD C NGG C TC CP G+ GK
Sbjct: 515 PDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGK 574
Query: 1516 RCNTP---ICLQ-KCKNGGECIAPS---ICHCPSSWEGVRCQI----PICNPKCLYGGRC 1564
C +C C+NGG C C CP + G C+I + C GG C
Sbjct: 575 HCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 634
Query: 1565 ---IFPNVCSCRTEYSGVKCE 1582
I C C +SG CE
Sbjct: 635 FHYIGKYKCDCPPGFSGRHCE 655
Score = 149 bits (376), Expect = 2e-35
Identities = 106/316 (33%), Positives = 137/316 (43%), Gaps = 51/316 (16%)
Query: 1319 GYIGSNCQTALCDPDCKNHGKCIKPNI-------CQCLPGHGGATC--DEEHC-NPPCQH 1368
G G L C N GKCI + C CL G G C D C + PCQ+
Sbjct: 263 GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQN 322
Query: 1369 GGTCLAGN---LCTCPYGFVGPRCETMVC---NRHCENGGQCLTPD---ICQCKPGWYGP 1419
GGTC G C CP GF GP CET + C++GGQC + +C C+ G+ G
Sbjct: 323 GGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGA 382
Query: 1420 TCSTAL--CDP-VCLNGGSCNK---PNTCLCPNGFFGEHCQ-------NAFCHPPCKNGG 1466
C + C P CLNGGSC TCLC F G C+ +A PC NGG
Sbjct: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
Query: 1467 HCM---RNNVCVCREGYTGRRFQKSICDP-TCMNGGKCVGPST--CSCPSGWSGKRCNTP 1520
C+ + VC C EG+ G ++ + D C NGG+C+G +T C CP G+ G C
Sbjct: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFE 502
Query: 1521 ICLQ------KCKNGGECI---APSICHCPSSWEGVR-CQIPICNPKCLYGGRCIFPN-- 1568
I +C +GG C+ +C C + P + C GG C +
Sbjct: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDS 562
Query: 1569 -VCSCRTEYSGVKCEK 1583
C C + G CEK
Sbjct: 563 YTCECPRGFHGKHCEK 578
Score = 139 bits (350), Expect = 2e-32
Identities = 134/482 (27%), Positives = 186/482 (38%), Gaps = 124/482 (25%)
Query: 1181 CDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSN---PCGLGSY-ISGF 1236
C+C NGG C+ G+ LC C GF G LCE +I+ N C G Y +
Sbjct: 472 CECRNGGRCL-------GANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHG 524
Query: 1237 HSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFT 1296
SY C C D NA H P+ ++
Sbjct: 525 GSYLCVC-------------------------------HTDHNAS----HSLPSPCDSD- 548
Query: 1297 ICKYPCGKSRECVAPN---ICKCKPGYIGSNCQTA---LCDPD-CKNHGKCIKPN---IC 1346
PC C A + C+C G+ G +C+ A LC C+N G C + C
Sbjct: 549 ----PCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
Query: 1347 QCLPGHGGATCD----EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCETMV--CNRH 1397
C G C+ + + PC +GGTC + C CP GF G CE C R
Sbjct: 605 SCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 664
Query: 1398 -CENGGQCLTPD---ICQCKPGWYGPTCSTAL-CDP----------------------VC 1430
C NGG C D C C+ G+ G C + C P C
Sbjct: 665 PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
Query: 1431 LNGGSCNKPNTC-LC-PNGFFGEHCQ----NAFCHPPCKNGGHC---MRNNVCVCREGYT 1481
G S + P+ +C P+G + E Q + PC +GG C + +C+C GY
Sbjct: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
Query: 1482 GRR--FQKSICDP-TCMNGGKC---VGPSTCSCPSGWSGKRCNTPI--C-LQKCKNGGEC 1532
G ++ C C NGG C G C CP+G+ G C T + C C++GG C
Sbjct: 785 GAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC 844
Query: 1533 IAPS---ICHCPSSWEGVRCQI---PICNPKCLYGGRCIFPN---VCSCRTEYSGVKCEK 1583
+ +C CP S+ G C+ P + C G C+ N C+C+ Y+G C K
Sbjct: 845 ESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAK 904
Query: 1584 KI 1585
++
Sbjct: 905 EL 906
Score = 120 bits (302), Expect = 8e-27
Identities = 105/379 (27%), Positives = 136/379 (35%), Gaps = 121/379 (31%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDI-SGCQSNPCGLGSYISGFH---S 1238
C NGG+C G Y C C F G CE+ C S PC G + FH
Sbjct: 589 CRNGGTC------KEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGG--TCFHYIGK 640
Query: 1239 YSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTIC 1298
Y CDCPP GR + P+
Sbjct: 641 YKCDCPPGFS---------------------------------GRHCEIAPSP-----CF 662
Query: 1299 KYPCGKSRECVAPN---ICKCKPGYIGSNCQTAL-CDPD--------------------- 1333
+ PC C + C C+ GY+G CQ + C P
Sbjct: 663 RSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALY 722
Query: 1334 ----------------CKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTC---LA 1374
C+ HG +P QCL +E + PC HGG+C +A
Sbjct: 723 ACDRGYSLSAPSRIRVCQPHGVWSEPP--QCLE-------IDECRSQPCLHGGSCQDRVA 773
Query: 1375 GNLCTCPYGFVGPRCETM--VCNRH-CENGGQCLTPD---ICQCKPGWYGPTCSTAL--C 1426
G LC C G+ G CE C H C NGG C +C+C G+ G C T + C
Sbjct: 774 GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC 833
Query: 1427 DPV-CLNGGSCNKPN---TCLCPNGFFGEHCQ---NAFCHPPCKNGGHCMRNN---VCVC 1476
D C +GG C C+CP FFG HC+ + PC G+C+ +N C C
Sbjct: 834 DSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC 893
Query: 1477 REGYTGRRFQKSICDPTCM 1495
+ GYTG K + PT +
Sbjct: 894 KVGYTGEDCAKELFPPTAL 912
Score = 103 bits (258), Expect = 1e-21
Identities = 77/248 (31%), Positives = 100/248 (40%), Gaps = 70/248 (28%)
Query: 1408 DICQCKPGWYGPTCSTALCDPVCLNGGSC-------NKPNTCLCPNGFFGEHCQ---NAF 1457
D Q + G G T S L CLNGG C N TC C +GF G C N
Sbjct: 256 DDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC 315
Query: 1458 CHPPCKNGGHCMR-----------------------------------------NNVCVC 1476
PC+NGG C + VCVC
Sbjct: 316 ASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVC 375
Query: 1477 REGYTGRRFQKSI--CDP-TCMNGGKC---VGPSTCSCPSGWSGKRCNT---PI---CLQ 1524
+ GYTG + + C P C+NGG C VG TC C + G RC T P+ CL
Sbjct: 376 QAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS 435
Query: 1525 -KCKNGGECIAPS---ICHCPSSWEGVRCQIPICNP-KCLYGGRCIFPN--VCSCRTEYS 1577
C NGG C+ +C CP + G+ C+ + + +C GGRC+ N +C C +
Sbjct: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFF 495
Query: 1578 GVKCEKKI 1585
G+ CE +I
Sbjct: 496 GLLCEFEI 503
Score = 55.5 bits (132), Expect = 4e-07
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 20/163 (12%)
Query: 1179 KSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGF-H 1237
+S CL+GGSC DR YLC+C G+ G+ CE++ C+++PC G
Sbjct: 758 RSQPCLHGGSC-QDRVAG-----YLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPG 811
Query: 1238 SYSCDCPP-----ELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSG 1292
+Y C CP + E + Q S ++ G H + S
Sbjct: 812 AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG--YHCETVSD 869
Query: 1293 NAFTICKYPCGKSRECVAPN---ICKCKPGYIGSNCQTALCDP 1332
F+ PCG C+A N C CK GY G +C L P
Sbjct: 870 PCFS---SPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPP 909
Score = 52.8 bits (125), Expect = 3e-06
Identities = 35/89 (39%), Positives = 40/89 (44%), Gaps = 19/89 (21%)
Query: 1172 VTIEVTVKSCD---CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCG 1228
V E V +CD C +GG C S G G YLCVC F G CE C S+PCG
Sbjct: 824 VHCETEVDACDSSPCQHGGRCES------GGGAYLCVCPESFFGYHCETVSDPCFSSPCG 877
Query: 1229 LGSYI---SGFHSYSC-------DCPPEL 1247
Y +G HS +C DC EL
Sbjct: 878 GRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 38.5 bits (88), Expect = 0.052
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 14/52 (26%)
Query: 1349 LPGHGG-------ATCDEEHCNPPCQHGGTCLAG---NLCTCPYGFVGPRCE 1390
LP HG C E PCQ+GGTC+ G + C C GF G RCE
Sbjct: 1296 LPEHGSKDIGNVPGNCSEN----PCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 36.2 bits (82), Expect = 0.26
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 6/35 (17%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEV 1217
C NGG+CV PG+ + C C PGF G CE+
Sbjct: 1316 CQNGGTCV------PGADAHSCDCGPGFKGRRCEL 1344
Score = 31.2 bits (69), Expect = 8.4
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 1201 VYLCVCLPGFHGSLCEVDISG-CQSNPC-GLGSYISGFHSYSCDCPPELK 1248
V L + LP HGS ++ G C NPC G+ + G ++SCDC P K
Sbjct: 1290 VSLALQLPE-HGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFK 1338
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 187 bits (475), Expect = 7e-47
Identities = 149/474 (31%), Positives = 203/474 (42%), Gaps = 93/474 (19%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C NGG+C N Y C C GF G CE +I+ C + C G+ + G +S+SC
Sbjct: 958 CKNGGTCSDYVNS------YTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSC 1011
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKP---TSGNAFTI- 1297
CP F F + S +N E + G R P T N T+
Sbjct: 1012 LCP------VGFTGSFCLHEINECSSHPCLN-EGTCVDGLGTYRCSCPLGYTGKNCQTLV 1064
Query: 1298 ---CKYPCGKSRECV---APNICKCKPGYIGSNCQT-------------ALCDPDCKNHG 1338
+ PC CV A + C C G+ G+ C L + C++ G
Sbjct: 1065 NLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSG 1124
Query: 1339 KCI---KPNICQCLPGHGGATCDE---EHCNPPCQHGGTC---LAGNLCTCPYGFVGPRC 1389
CI + CQC G+ G+ C+E E + PCQHG TC + G C C G+ G C
Sbjct: 1125 VCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNC 1184
Query: 1390 ETMV--C-NRHCENGGQCLTPDI-----CQCKPGWYGPTCSTALCD----PVCLNGGSCN 1437
E V C N+ C+NGG C+ D+ C C PG G C + D P CLNGG C
Sbjct: 1185 EYEVDECQNQPCQNGGTCI--DLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM 1242
Query: 1438 K---PNTCLCPNGFFGEHCQ---NAFCHPPCKNGG--HCMR---NNVCVCREGYTGRRFQ 1486
+C C GF GE C+ N PC + G C++ + +CVCR +TGR +
Sbjct: 1243 DRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Query: 1487 K--SIC-DPTCMNGGKCVGPST------CSCPSGWSGKRCNTPICLQKCKNGGECIAPSI 1537
+C C+NGG C S C CP G+SG RC + KC+ G +C+ +
Sbjct: 1303 TFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTAS 1362
Query: 1538 ---CHCPSSWEGVRCQIPICNPKCLYGGRCIFPN------VCSCRTEYSGVKCE 1582
C CPS + C+ + C +GG C P C C +SG +CE
Sbjct: 1363 GPRCFCPSPRD---CESGCASSPCQHGGSC-HPQRQPPYYSCQCAPPFSGSRCE 1412
Score = 182 bits (461), Expect = 3e-45
Identities = 152/489 (31%), Positives = 201/489 (41%), Gaps = 114/489 (23%)
Query: 1166 CDAE-TRVTIEVTVKSC---DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISG 1221
CDA + EV C C NGG+C N G Y C C GF G C+V+I
Sbjct: 745 CDAGWVGINCEVDKNECLSNPCQNGGTC---DNLVNG---YRCTCKKGFKGYNCQVNIDE 798
Query: 1222 CQSNPC-GLGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNA 1280
C SNPC G+ Y+C C V +T KN
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHC----------VLPYT------------------GKNC 830
Query: 1281 QGRKRHVKPTSGNAFTICKYPCGKSRECV-APNI----CKCKPGYIGSNCQTALCD---P 1332
Q + P S N PC + C +PN C C PG+ G C + +
Sbjct: 831 Q---TVLAPCSPN-------PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 1333 DCKNHGKCIKPN---ICQCLPGHGGATCDEEHCN---PPCQHGGTCLAGN---LCTCPYG 1383
C NHG C +C+C PG G C+E+ + PCQ+GG+C+ G C C G
Sbjct: 881 PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPG 940
Query: 1384 FVGPRCETMV---CNRHCENGGQC---LTPDICQCKPGWYGPTCSTAL---CDPVCLNGG 1434
F G +C+T + + C+NGG C + C+C+ G+ G C + + C NGG
Sbjct: 941 FTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGG 1000
Query: 1435 SCN---KPNTCLCPNGFFGEHCQ---NAFCHPPCKNGGHC---MRNNVCVCREGYTGRRF 1485
+C +CLCP GF G C N PC N G C + C C GYTG+
Sbjct: 1001 TCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Query: 1486 QK--SICDPT-CMNGGKCV---GPSTCSCPSGWSGKRCNTP-------------ICLQKC 1526
Q ++C + C N G CV S C CPSGW+G C+ P + C
Sbjct: 1061 QTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLC 1120
Query: 1527 KNGGECIAPS---ICHCPSSWEGVRC--QIPIC--NPKCLYGGRC---IFPNVCSCRTEY 1576
++ G CI C CP + G C Q+ C NP C +G C I C C Y
Sbjct: 1121 QHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP-CQHGATCSDFIGGYRCECVPGY 1179
Query: 1577 SGVKCEKKI 1585
GV CE ++
Sbjct: 1180 QGVNCEYEV 1188
Score = 165 bits (418), Expect = 3e-40
Identities = 132/481 (27%), Positives = 195/481 (40%), Gaps = 86/481 (17%)
Query: 1181 CDCLNGGS---------------CVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSN 1225
C+CL G + C +D G + C+C+PGF G CE++I+ CQSN
Sbjct: 442 CECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSN 501
Query: 1226 PC-GLGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRK 1284
PC G + + + C CPP ++ + K + D N
Sbjct: 502 PCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI----DHPNGY--- 554
Query: 1285 RHVKPTSGNAFTICKY--------PC--GKSRECVAPNICKCKPGYIGSNCQTALCD--- 1331
+ +G +C+ PC G+ ++ + C C PGY+G+ C + +
Sbjct: 555 -ECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYS 613
Query: 1332 PDCKNHGKCI---KPNICQCLPGHGGATCD---EEHCNPPCQHGGTCLAG---NLCTCPY 1382
C N G+CI C C PG G C+ ++ + PC H G C+ G C C
Sbjct: 614 SPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVCSP 672
Query: 1383 GFVGPRCETMV---CNRHCENGGQCL---TPDICQCKPGWYGPTC----STALCDPVCLN 1432
GF G RC + + C G C+ C C G + P+C + L +P C++
Sbjct: 673 GFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNP-CIH 731
Query: 1433 GGSCN--KPNTCLCPNGFFGEHCQ---NAFCHPPCKNGGHC---MRNNVCVCREGYTGRR 1484
G CLC G+ G +C+ N PC+NGG C + C C++G+ G
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYN 791
Query: 1485 FQKSI---CDPTCMNGGKC---VGPSTCSCPSGWSGKRCNT---PICLQKCKNGGEC--- 1532
Q +I C+N G C + TC C ++GK C T P C+N C
Sbjct: 792 CQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKES 851
Query: 1533 --IAPSICHCPSSWEGVRCQIPI--CNPK-CLYGGRCIFPN---VCSCRTEYSGVKCEKK 1584
C C W+G RC I I C K C+ G C +C C +SG+ CE+
Sbjct: 852 PNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEED 911
Query: 1585 I 1585
I
Sbjct: 912 I 912
Score = 165 bits (418), Expect = 3e-40
Identities = 138/464 (29%), Positives = 183/464 (39%), Gaps = 71/464 (15%)
Query: 1180 SCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSY 1239
S CLNG C+ N Y C C GF G LCE +I C +PC G G SY
Sbjct: 538 STPCLNGAKCIDHPNG------YECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSY 591
Query: 1240 SCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKP-TSG-----N 1293
+C C P ++ + + S +N G + + +P TSG N
Sbjct: 592 TCICNP------GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEIN 645
Query: 1294 AFTICKYPC--GKSRECVAPNICKCKPGYIGSNCQTAL---CDPDCKNHGKCIK-----P 1343
PC G + + C C PG+ G C + C+ CI
Sbjct: 646 FDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705
Query: 1344 NICQCLPGHGGATCDEEHC-NPPCQHGGTC--LAGNLCTCPYGFVGPRCE---TMVCNRH 1397
IC P H C + PC HG L+G C C G+VG CE +
Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNP 765
Query: 1398 CENGGQC---LTPDICQCKPGWYGPTCSTAL---CDPVCLNGGSC---NKPNTCLCPNGF 1448
C+NGG C + C CK G+ G C + CLN G+C TC C +
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY 825
Query: 1449 FGEHCQN--AFCHP-PCKNGGHC-----MRNNVCVCREGYTGRR----FQKSICDPTCMN 1496
G++CQ A C P PC+N C + C+C G+ G+R + I P CMN
Sbjct: 826 TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP-CMN 884
Query: 1497 GGKC---VGPSTCSCPSGWSGKRCNTPI--CL-QKCKNGGEC---IAPSICHCPSSWEGV 1547
G C G C CP G+SG C I CL C+NGG C + C C + G
Sbjct: 885 HGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGD 944
Query: 1548 RCQIPI---CNPKCLYGGRC---IFPNVCSCRTEYSGVKCEKKI 1585
+CQ + + C GG C + C C+ + GV CE I
Sbjct: 945 KCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI 988
Score = 163 bits (412), Expect = 1e-39
Identities = 142/480 (29%), Positives = 199/480 (41%), Gaps = 104/480 (21%)
Query: 1171 RVTIEVT-VKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-G 1228
R TI++ S C+N G C + + G Y+C C PGF G CE DI C +NPC
Sbjct: 869 RCTIDIDECISKPCMNHGLCHNTQ------GSYMCECPPGFSGMDCEEDIDDCLANPCQN 922
Query: 1229 LGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVK 1288
GS + G +++SC C P + ++D + E KN +V
Sbjct: 923 GGSCMDGVNTFSCLCLPGFTGDK-------------CQTDMNECLSEPCKNGGTCSDYV- 968
Query: 1289 PTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL---CDPDCKNHGKC---IK 1342
N++T CKC+ G+ G +C+ + + C N G C I
Sbjct: 969 ----NSYT-----------------CKCQAGFDGVHCENNINECTESSCFNGGTCVDGIN 1007
Query: 1343 PNICQCLPGHGGATCDEE--HCNP-PCQHGGTCLAG---NLCTCPYGFVGPRCETMV--C 1394
C C G G+ C E C+ PC + GTC+ G C+CP G+ G C+T+V C
Sbjct: 1008 SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLC 1067
Query: 1395 NRH-CENGGQCLTPDI---CQCKPGWYGPTCST-------------ALCDPVCLNGGSC- 1436
+R C+N G C+ C C GW G C L + +C + G C
Sbjct: 1068 SRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI 1127
Query: 1437 NKPNT--CLCPNGFFGEHCQNAF---CHPPCKNGGHC---MRNNVCVCREGYTGRRFQKS 1488
N NT C CP G+ G +C+ PC++G C + C C GY G +
Sbjct: 1128 NAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE 1187
Query: 1489 ICD---PTCMNGGKC---VGPSTCSCPSGWSGKRCNTPI--CLQ--KCKNGGEC---IAP 1535
+ + C NGG C V CSCP G G C I C + C NGG+C I
Sbjct: 1188 VDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGG 1247
Query: 1536 SICHCPSSWEGVRCQIPI----CNPKCLYGGR-CIFPN---VCSCRTEYSGVKCEKKIQI 1587
C C + G RC+ I NP G CI +C CR+ ++G CE + +
Sbjct: 1248 YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDV 1307
Score = 148 bits (374), Expect = 4e-35
Identities = 146/507 (28%), Positives = 194/507 (38%), Gaps = 142/507 (28%)
Query: 1175 EVTVKSCD----CLNGGSCVSDRNFSPGSGVYLCV------------------------- 1205
E V CD C +GG+C++ PGS Y C
Sbjct: 180 ETDVNECDIPGHCQHGGTCLN----LPGS--YQCQCPQGFTGQYCDSLYVPCAPSPCVNG 233
Query: 1206 --------------CLPGFHGSLCEVDISGCQSNPCGLGSY-ISGFHSYSCDCPPELKVE 1250
CLPGF GS CE +I C ++ C G + G ++Y+C CPP
Sbjct: 234 GTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPP----- 288
Query: 1251 TQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVA 1310
Q+ QF T+ V D+ + ++P + C C
Sbjct: 289 -QWTGQFCTEDV-----DECL---------------LQPNA----------CQNGGTCAN 317
Query: 1311 PN---ICKCKPGYIGSNCQTALCD---PDCKNHGKCI---KPNICQCLPGHGGATC--DE 1359
N C C G+ G +C + D C CI C C G G C D+
Sbjct: 318 RNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDD 377
Query: 1360 EHCNPPCQHGGTC----LAGN-LCTCPYGFVGPRCE------TMVCNRHCENGGQCLTPD 1408
+ PC G C L G +CTCP G+ G C M + CE+ G+C+ D
Sbjct: 378 ACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTD 437
Query: 1409 ---ICQCKPGWYGPTCSTAL----CDPVCLNGGSCNKP---NTCLCPNGFFGEHCQ---N 1455
C+C G+ GP C + DP C N +C TCLC GF G HC+ N
Sbjct: 438 GAFHCECLKGYAGPRCEMDINECHSDP-CQNDATCLDKIGGFTCLCMPGFKGVHCELEIN 496
Query: 1456 AFCHPPCKNGGHC---MRNNVCVCREGYTGRRFQKSI--CDPT-CMNGGKCVGPST---C 1506
PC N G C + C+C G+TG Q I C T C+NG KC+ C
Sbjct: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYEC 556
Query: 1507 SCPSGWSGKRC--NTPICLQKCKNGGEC---IAPSICHCPSSWEGVRC--QIPIC-NPKC 1558
C +G++G C N C + G+C I C C + G C QI C + C
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 1559 LYGGRCI---FPNVCSCRTEYSGVKCE 1582
L GRCI C+C+ SGV CE
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCE 643
Score = 147 bits (372), Expect = 6e-35
Identities = 114/340 (33%), Positives = 152/340 (44%), Gaps = 59/340 (17%)
Query: 1301 PCGKSRECVA----PNICKCKPGYIGSNCQ-TALCDPD-CKNHGKCIKPNI-----CQCL 1349
PC CV CKC G++G CQ C+ + C+N G C+ + C+C
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCA 93
Query: 1350 PGHGGATCDEEHCNP-----PCQHGGTC--LAGNL--CTCPYGFVGPRCE-TMVCNRH-C 1398
G G C +P PC +GGTC L+ + CTC GF G C+ T C H C
Sbjct: 94 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPC 153
Query: 1399 ENGGQCLT---PDICQCKPGWYGPTCSTAL--CD--PVCLNGGSC-NKPNT--CLCPNGF 1448
NG C T C+C G+ G C T + CD C +GG+C N P + C CP GF
Sbjct: 154 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF 213
Query: 1449 FGEHCQNAF--CHP-PCKNGGHCMRNN----VCVCREGYTGRRFQKSICD---PTCMNGG 1498
G++C + + C P PC NGG C + C C G+ G +++I D C NGG
Sbjct: 214 TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGG 273
Query: 1499 KCV-GPST--CSCPSGWSGKRCNTPI--CL---QKCKNGGECIAPS---ICHCPSSWEGV 1547
CV G +T C CP W+G+ C + CL C+NGG C + C C + W G
Sbjct: 274 VCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
Query: 1548 RCQIPICN---PKCLYGGRCI---FPNVCSCRTEYSGVKC 1581
C I + C G CI C C +G+ C
Sbjct: 334 DCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLC 373
Score = 147 bits (371), Expect = 8e-35
Identities = 146/516 (28%), Positives = 191/516 (37%), Gaps = 137/516 (26%)
Query: 1164 DDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQ 1223
+DC T V S CLNGG+C Y C C GF G C+ C
Sbjct: 99 EDCQYSTSHPCFV---SRPCLNGGTC-----HMLSRDTYECTCQVGFTGKECQW-TDACL 149
Query: 1224 SNPCGLGSYISGF-HSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQG 1282
S+PC GS + + +SC C + FT Q K E D N
Sbjct: 150 SHPCANGSTCTTVANQFSCKC----------LTGFTGQ------------KCETDVNECD 187
Query: 1283 RKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL--CDPD-CKNHGK 1339
H C++ G C+C G+ G C + C P C N G
Sbjct: 188 IPGH-----------CQHG-GTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGT 235
Query: 1340 CIKPN----ICQCLPGHGGATCDE--EHC-NPPCQHGGTCLAG---NLCTCPYGFVGPRC 1389
C + C CLPG G+TC+ + C N CQ+GG C+ G C CP + G C
Sbjct: 236 CRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
Query: 1390 -----ETMVCNRHCENGGQCLTPD---ICQCKPGWYGPTCSTALCD---PVCLNGGSC-- 1436
E ++ C+NGG C + C C GW G CS + D C G +C
Sbjct: 296 TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
Query: 1437 -NKPNTCLCPNGFFGE--HCQNAFCHPPCKNGGHCMRN-----NVCVCREGYTGRRFQKS 1488
+C+CP G G H +A PC G C N +C C +GY G +
Sbjct: 356 RVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED 415
Query: 1489 ICD------PTCMNGGKCV---GPSTCSCPSGWSGKRC-------------NTPICLQK- 1525
+ + C + GKCV G C C G++G RC N CL K
Sbjct: 416 VDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKI 475
Query: 1526 ---------------------------CKNGGECIAP---SICHCPSSWEGVRCQIPI-- 1553
C N G+C+ C CP + G CQI I
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDD 535
Query: 1554 -CNPKCLYGGRCI-FPN--VCSCRTEYSGVKCEKKI 1585
+ CL G +CI PN C C T ++GV CE+ I
Sbjct: 536 CSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
Score = 136 bits (342), Expect = 2e-31
Identities = 135/465 (29%), Positives = 193/465 (41%), Gaps = 77/465 (16%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSY-----ISGFH 1237
C G +C+ DR S + C+C G G LC +D C SNPC G+ ++G
Sbjct: 347 CTPGSTCI-DRVAS-----FSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNG-- 397
Query: 1238 SYSCDCPPELKVE--TQFVNQFT-TQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNA 1294
Y C CP K T+ V++ + + K VN + + + K + P
Sbjct: 398 QYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN-TDGAFHCECLKGYAGPRCEMD 456
Query: 1295 FTIC-KYPCGKSREC---VAPNICKCKPGYIGSNCQTAL--CDPD-CKNHGKCI-KPNIC 1346
C PC C + C C PG+ G +C+ + C + C N+G+C+ K N
Sbjct: 457 INECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRF 516
Query: 1347 QCL--PGHGGATC--DEEHC-NPPCQHGGTCL---AGNLCTCPYGFVGPRCETMV--CNR 1396
QCL PG G C D + C + PC +G C+ G C C GF G CE + C+
Sbjct: 517 QCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
Query: 1397 HCENGGQC---LTPDICQCKPGWYGPTCSTALCD---PVCLNGGSC---NKPNTCLCPNG 1447
+ GQC + C C PG+ G CS + + CLN G C C C G
Sbjct: 577 DPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 1448 FFGEHCQNAF---CHPPCKNGGHCM---RNNVCVCREGYTGRRFQKSICD---------P 1492
G +C+ F PC + G CM CVC G+TG+R I +
Sbjct: 637 TSGVNCEINFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGA 695
Query: 1493 TCMNGGKCVGPSTCSCPSGWSGKRCNTPI--CLQKCKNGGEC---IAPSICHCPSSWEGV 1547
TC+NG V C CP G C + + CL G C ++ C C + W G+
Sbjct: 696 TCING---VNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGI 752
Query: 1548 RCQIP----ICNPKCLYGGRC---IFPNVCSCRTEYSGVKCEKKI 1585
C++ + NP C GG C + C+C+ + G C+ I
Sbjct: 753 NCEVDKNECLSNP-CQNGGTCDNLVNGYRCTCKKGFKGYNCQVNI 796
Score = 105 bits (262), Expect = 3e-22
Identities = 71/229 (31%), Positives = 97/229 (42%), Gaps = 43/229 (18%)
Query: 1398 CENGGQCLT----PDICQCKPGWYGPTCSTALCDPV----CLNGGSCNKPN-----TCLC 1444
C N G C+T C+C G+ G C DP C NGG+C TC C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR--DPCEKNRCQNGGTCVAQAMLGKATCRC 92
Query: 1445 PNGFFGEHCQNAFCHP-----PCKNGGHC----MRNNVCVCREGYTGRRFQ--KSICDPT 1493
+GF GE CQ + HP PC NGG C C C+ G+TG+ Q +
Sbjct: 93 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 152
Query: 1494 CMNGGKC---VGPSTCSCPSGWSGKRCNTPI----CLQKCKNGGECI---APSICHCPSS 1543
C NG C +C C +G++G++C T + C++GG C+ C CP
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 1544 WEGVRCQ---IPICNPKCLYGGRC----IFPNVCSCRTEYSGVKCEKKI 1585
+ G C +P C+ GG C F C+C + G CE+ I
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNI 261
Score = 95.9 bits (237), Expect = 3e-19
Identities = 102/418 (24%), Positives = 150/418 (35%), Gaps = 92/418 (22%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C +G +C S G Y C C+PG+ G CE ++ CQ+ PC G+ I + + C
Sbjct: 1158 CQHGATC------SDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKC 1211
Query: 1242 DCPPELKVETQFVNQFTTQTVV-LTRSDKSVNKEEDDKNAQGRKRHVKP------TSGNA 1294
CPP + + + R +N + G P G+
Sbjct: 1212 SCPPGTR------GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDI 1265
Query: 1295 FTICKYPCGK--SRECVAPN---ICKCKPGYIGSNCQTAL--CDP-DCKNHGKCIKPN-- 1344
PC S +C+ +C C+ + G +C+T + C C N G C +
Sbjct: 1266 NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
Query: 1345 ----ICQCLPGHGGATCDEEHCNPPCQHGGTCL---AGNLCTCPYGFVGPR-CETMVCNR 1396
IC+C PG GA C C+ G C+ +G C CP PR CE+ +
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCP----SPRDCESGCASS 1381
Query: 1397 HCENGGQCLTPD-----ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGE 1451
C++GG C CQC P + G C P P TCL + + +
Sbjct: 1382 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPP-------STPPATCL--SQYCAD 1432
Query: 1452 HCQNAFCHPPCK------NGGHC---MRNNVCVCREGYTGRRFQKSICDPTC------MN 1496
++ C C +GG C M N C + + CD C +
Sbjct: 1433 KARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFD 1492
Query: 1497 GGKCVGPS-TCS----CPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRC 1549
+C G S TC C + C+ Q C N EC W+G+ C
Sbjct: 1493 NFECQGNSKTCKYDKYCADHFKDNHCD-----QGC-NSEEC----------GWDGLDC 1534
Score = 34.7 bits (78), Expect = 0.76
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 4/44 (9%)
Query: 882 EDILSVLKCPNLCSGNGQCME----WGCACSPSFSSYDCSDSYD 921
ED+ L PN C G C +GC C +S DCS++ D
Sbjct: 297 EDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENID 340
Score = 33.9 bits (76), Expect = 1.3
Identities = 22/67 (32%), Positives = 25/67 (37%), Gaps = 8/67 (11%)
Query: 883 DILSVLKCPNLCSGNGQCMEWG-----CACSPSFSSYDCSDSYDKAPEITELGNAGFC-- 935
D L V P+ C G C + G C C P F C + D P N G C
Sbjct: 219 DSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPN-HRCQNGGVCVD 277
Query: 936 DVQKYNC 942
V YNC
Sbjct: 278 GVNTYNC 284
Score = 31.6 bits (70), Expect = 6.4
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 4/38 (10%)
Query: 1180 SCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEV 1217
S C +GGSC R Y C C P F GS CE+
Sbjct: 1380 SSPCQHGGSCHPQRQ----PPYYSCQCAPPFSGSRCEL 1413
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 185 bits (470), Expect = 3e-46
Identities = 160/533 (30%), Positives = 211/533 (39%), Gaps = 139/533 (26%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGS-YISGFHSYSC 1241
C +GGSC++ +PGS + C+C PG+ GS CE D + C S PC GS + ++ C
Sbjct: 446 CEHGGSCLN----TPGS--FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Query: 1242 DCPPEL-----KVET---------------QFVNQFTTQTVVL-----TRSDKSVNKEED 1276
CPP L +VET +N F Q + L TR ++ +++
Sbjct: 500 LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF--QCICLPGFSGTRCEEDIDECRS 557
Query: 1277 DKNAQGRK-------RHVKPTSGNAFTICKY--------PCGKSRECV---APNICKCKP 1318
A G + H K G C+ PC C+ C C
Sbjct: 558 SPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
Query: 1319 GYIGSNCQTALCDP----------DCKNHGKCIKPNICQ-CLPGHGGATCDEEHC----- 1362
G+ G C+ LC P D K+ C+ P+ C P TC HC
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
Query: 1363 -------------------NPPCQHGGTCL---AGNLCTCPYGFVGPRCETMVCNRH--- 1397
+ PC HGGTC +G CTCP G+ GP C + H
Sbjct: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
Query: 1398 CENGGQCLTPD----ICQCKPGWYGPTCSTA---LCDPVCLNGGSC-NKPNT--CLCPNG 1447
C NGG C P C C P GP C T+ C NGG+C N+P T CLC G
Sbjct: 738 CLNGGSC-NPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Query: 1448 FFGEHCQN----AFCHPPCKNGGHCM---RNNVCVCREGYTGRRFQ--KSIC-DPTCMNG 1497
F G C+ + PC+N C + C+C GYTG Q +C C
Sbjct: 797 FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRN 856
Query: 1498 GKCV--GPS-TCSCPSGWSGKRCNTPI-CLQK------------CKNGGECI--APS-IC 1538
C+ GPS C C GW+G CN P+ QK C NGG C+ PS C
Sbjct: 857 SHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 1539 HCPSSWEGVRCQ---IPICNPKCLYGGRCIFP---NVCSCRTEYSGVKCEKKI 1585
HCP ++G CQ P + C G C+ +C C Y G C K++
Sbjct: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL 969
Score = 163 bits (413), Expect = 1e-39
Identities = 148/492 (30%), Positives = 195/492 (39%), Gaps = 98/492 (19%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSY-ISGFHSYSC 1241
C NGG+C + +G + CVC+ G+ G+ CE ++ C + C GS I S+SC
Sbjct: 326 CRNGGTCQNS------AGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC 379
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKY- 1300
CPP + + S N + + PT C
Sbjct: 380 LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439
Query: 1301 -----PCGKSRECV-APNI--CKCKPGYIGSNCQT----ALCDPDCKNHGKCIKPNI--- 1345
PC C+ P C C PGY GS C+ L P C C+
Sbjct: 440 QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCLDLLATFH 498
Query: 1346 CQCLPGHGGATCD---EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCETMV--CNRH 1397
C C PG G C+ E + PC + C L G C C GF G RCE + C
Sbjct: 499 CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSS 558
Query: 1398 -CENGGQCLTPD---ICQCKPGWYGPTCST----ALCDPVCLNGGSC-NKPNT--CLCPN 1446
C NGGQC C+C PG+ GP C T L DP C G SC + P CLCP+
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP-CPVGASCLDLPGAFFCLCPS 617
Query: 1447 GFFGEHCQNAFCHPP------------------CKNG---------------GHCMRNNV 1473
GF G+ C+ C P C +G GHC R++
Sbjct: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS- 676
Query: 1474 CVCREGYTGRRFQKSI---CDPTCMNGGKCVG-PS--TCSCPSGWSGKRCN---TPICLQ 1524
CVC G+TG + + C +GG C PS C+CP+G++G C+ T
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG 736
Query: 1525 KCKNGGECIAPS----ICHCPSSWEGVRCQIPI---CNPKCLYGGRCIF-PNV--CSCRT 1574
C NGG C PS C CP S G +CQ + C GG C+ P C C
Sbjct: 737 PCLNGGSC-NPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAM 795
Query: 1575 EYSGVKCEKKIQ 1586
+ G +CE K++
Sbjct: 796 GFQGPRCEGKLR 807
Score = 156 bits (394), Expect = 2e-37
Identities = 143/501 (28%), Positives = 195/501 (38%), Gaps = 111/501 (22%)
Query: 1183 CLNGGSCVSDRNFSP--GSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSY 1239
C NGG+C P S +LC+C PGF G CEV+ C S+ C G+ G +Y
Sbjct: 243 CSNGGTC----QLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTY 298
Query: 1240 SCDCPPELKVE--TQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTI 1297
+C CP ++ V++ TQ R+ + +N+ G H SG T
Sbjct: 299 TCLCPETWTGWDCSEDVDECETQGPPHCRNGGTC------QNSAG-SFHCVCVSGWGGTS 351
Query: 1298 CK--------YPCGKSREC---VAPNICKCKPGYIGSNC--QTALCDPDCKNHGKC---- 1340
C+ C C V C C PG G C + C +C
Sbjct: 352 CEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNP 411
Query: 1341 -IKPNICQCLPGHGGATC--DEEHC------NPPCQHGGTCL--AGNL-CTCPYGFVGPR 1388
+C C PG+ G TC D + C PC+HGG+CL G+ C CP G+ G R
Sbjct: 412 LTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSR 471
Query: 1389 CE---TMVCNRHCENGGQC---LTPDICQCKPGWYGPTC---STALCDPVCLNGGSCN-- 1437
CE ++ C G C L C C PG G C + CLN C+
Sbjct: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDL 531
Query: 1438 -KPNTCLCPNGFFGEHCQNAF--CH-PPCKNGGHCMRNN---VCVCREGYTGRRFQ---- 1486
C+C GF G C+ C PC NGG C C C G+ G R Q
Sbjct: 532 LNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVD 591
Query: 1487 KSICDPTCMNGGKCV---GPSTCSCPSGWSGKRCNTPICL-------QKC---KNGGECI 1533
+ + DP C G C+ G C CPSG++G+ C P+C Q C K+ C+
Sbjct: 592 ECLSDP-CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCL 650
Query: 1534 AP----------------------SICHCPSSWEGVRCQIPI---CNPKCLYGGRCIFPN 1568
P S C C W G C+ + + C +GG C +P
Sbjct: 651 CPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTC-YPQ 709
Query: 1569 V----CSCRTEYSGVKCEKKI 1585
C+C T Y+G C +++
Sbjct: 710 PSGYNCTCPTGYTGPTCSEEM 730
Score = 145 bits (365), Expect = 4e-34
Identities = 145/481 (30%), Positives = 183/481 (38%), Gaps = 123/481 (25%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEV-----DISGCQSN---------PCG 1228
C NGG+C+S S G G C C PGF G C+ + CQ+ P G
Sbjct: 35 CANGGTCLS---LSLGQGT--CQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLG 89
Query: 1229 LGSYISGF-HSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHV 1287
L S S S+ C C P E Q +
Sbjct: 90 LPSSPSPLTPSFLCTCLPGFTGE----------------------------RCQAKLEDP 121
Query: 1288 KPTSGNAFTICKYPCGKSREC----VAPNICKCKPGYIGSNCQTA-LCDPD-CKNHGKCI 1341
P S C K C C C PG+ G CQ C + C N G C+
Sbjct: 122 CPPSF---------CSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCL 172
Query: 1342 K--PNI-CQCLPGHGGATC--DEEHC--NP-PCQHGGTC---LAGNLCTCPYGFVGPRCE 1390
P I C C PG G C D C +P PC G +C L C CP G GPRCE
Sbjct: 173 ATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 1391 TMV--C-NRHCENGGQC-LTPD------ICQCKPGWYGPTCSTALCDPV---CLNGGSCN 1437
C R C NGG C L P+ +C C PG+ GP C + V C NGG+C
Sbjct: 233 LRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQ 292
Query: 1438 ---KPNTCLCPNGFFGEHCQNAF--CH----PPCKNGGHCMRNN---VCVCREGYTGRRF 1485
TCLCP + G C C P C+NGG C + CVC G+ G
Sbjct: 293 DGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSC 352
Query: 1486 QKSICD---PTCMNGGKC---VGPSTCSCPSGWSGKRCN-TPICL-QKCKNGGEC----- 1532
++++ D TC G C VG +C CP G +G C+ +CL Q C +C
Sbjct: 353 EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPL 412
Query: 1533 IAPSICHCPSSWEGVRCQIPICN--------PKCLYGGRCI-FPNV--CSCRTEYSGVKC 1581
++C C + G C + C +GG C+ P C C Y+G +C
Sbjct: 413 TGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRC 472
Query: 1582 E 1582
E
Sbjct: 473 E 473
Score = 142 bits (359), Expect = 2e-33
Identities = 135/488 (27%), Positives = 183/488 (37%), Gaps = 135/488 (27%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGC--QSNPCGLG-SYISGFHSY 1239
C+NGG C++ C C PGF G CE D++ C PC G S + S+
Sbjct: 165 CVNGGVCLATYP------QIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSF 218
Query: 1240 SCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICK 1299
C CP V Q R + + G + P + F +C
Sbjct: 219 QCLCP---------VGQEG------PRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263
Query: 1300 YPCG-KSREC-VAPNICKCKPGYIGSNCQ------TALC--------------------D 1331
P G +C V P+ C G CQ T LC
Sbjct: 264 CPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGP 323
Query: 1332 PDCKNHGKCIKPN---ICQCLPGHGGATCDE--EHC-NPPCQHGGTCL--AGNL-CTCPY 1382
P C+N G C C C+ G GG +C+E + C C G TC+ G+ C CP
Sbjct: 324 PHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPP 383
Query: 1383 GFVGPRC--ETMVCNRHCENGGQCLT-----PDICQCKPGWYGPTCSTALCDPV------ 1429
G G C E M ++ C QC T +C C+PG+ GPTC L + +
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP 443
Query: 1430 --CLNGGSC-NKPNT--CLCPNGFFGEHCQ-------NAFCHP----------------- 1460
C +GGSC N P + CLCP G+ G C+ + CHP
Sbjct: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP 503
Query: 1461 -----------------PCKNGGHC---MRNNVCVCREGYTGRRFQKSICD---PTCMNG 1497
PC N C + C+C G++G R ++ I + C NG
Sbjct: 504 GLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANG 563
Query: 1498 GKC---VGPSTCSCPSGWSGKRCNTPI--CL-QKCKNGGECI---APSICHCPSSWEGVR 1548
G+C G C C G+ G RC T + CL C G C+ C CPS + G
Sbjct: 564 GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL 623
Query: 1549 CQIPICNP 1556
C++P+C P
Sbjct: 624 CEVPLCAP 631
Score = 142 bits (358), Expect = 3e-33
Identities = 133/479 (27%), Positives = 183/479 (38%), Gaps = 76/479 (15%)
Query: 1183 CLNGGSCVS--------DRNFSPGSGVYLCVCLPGFHGSLCEVDISG-CQSNPCGLGS-- 1231
C NGGSC + + SP + +LC CLPGF G C+ + C + C
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRC 133
Query: 1232 YISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNA-QGRKRHVKPT 1290
+I C C P E + F + + + + G + H
Sbjct: 134 HIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER 193
Query: 1291 SGNAFTICKYPCGKSREC---VAPNICKCKPGYIGSNCQ--TALCDP-DCKNHGKC-IKP 1343
N PC K C + C C G G C+ C P C N G C + P
Sbjct: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMP 253
Query: 1344 ------NICQCLPGHGGATCD--EEHC-NPPCQHGGTCLAG---NLCTCPYGFVGPRCET 1391
++C C PG G C+ ++C + CQ+GGTC G C CP + G C
Sbjct: 254 EKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSE 313
Query: 1392 MV--CNR----HCENGGQCLTPD---ICQCKPGWYGPTCSTALCDPV---CLNGGSCNK- 1438
V C HC NGG C C C GW G +C L D + C G +C
Sbjct: 314 DVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDR 373
Query: 1439 --PNTCLCPNGFFGE--HCQNAFCHPPCKNGGHCMRN-----NVCVCREGYTGRRFQKSI 1489
+CLCP G G H ++ PC C N +C+C+ GY+G + +
Sbjct: 374 VGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDL 433
Query: 1490 CD--------PTCMNGGKCV---GPSTCSCPSGWSGKRCNTP--ICL-QKCKNGGEC--- 1532
+ C +GG C+ G C CP G++G RC CL Q C G C
Sbjct: 434 DECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDL 493
Query: 1533 IAPSICHCPSSWEGVRCQI---PICNPKCLYGGRC---IFPNVCSCRTEYSGVKCEKKI 1585
+A C CP EG C++ + CL C + C C +SG +CE+ I
Sbjct: 494 LATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDI 552
Score = 133 bits (334), Expect = 2e-30
Identities = 131/472 (27%), Positives = 183/472 (38%), Gaps = 93/472 (19%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
CLNGGSC +P G Y C C P G C+ C S PC G+ ++ ++SC
Sbjct: 738 CLNGGSC------NPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC 791
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTS---GNAFTI- 1297
C F + + +D +++ R + PT G+ T+
Sbjct: 792 LCA------MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 845
Query: 1298 ---CKYPCGKSRECV--APNI-CKCKPGYIG-------SNCQTALCDPD------CKNHG 1338
+ PC ++ C+ P+ C C G+ G S+CQ A C N G
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 1339 KCIKPN---ICQCLPGHGGATCDEEHCNP----PCQHGGTCLA---GNLCTCPYGFVGPR 1388
C+ C C PG G+ C ++H NP PCQ+G TC+A G LC C G+ G
Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLC-QDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQN 964
Query: 1389 C--ETMVC-NRHCENGGQCLTPDI----CQCKPGWYGPTCSTALCDPVCLNGGSCNKPNT 1441
C E C ++ C N G C TP C C PG+ G C + + CL+ C+ T
Sbjct: 965 CSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRCEGDVDE--CLDQ-PCHPTGT 1020
Query: 1442 -----------CLCPNGFFGEHCQNAF--CHP-PCKNGGHCMRNN------VCVCREGYT 1481
C C G G+ C+ CH PC +GG C +C C +G+
Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE 1080
Query: 1482 GRRFQK---SICDPTCMNGGKCVG------PSTCSCPSGWSGKRCNTPICLQKCKNGGEC 1532
G S C +GG C+ P C+C SG+ G C TP + C C
Sbjct: 1081 GPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
Query: 1533 IAPSICHCPS--SWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCE 1582
+ C + G RC P +P G RC P C C+
Sbjct: 1141 LYNGSCSETTGLGGPGFRCSCPHSSP----GPRCQKPGAKGCEGRSGDGACD 1188
Score = 78.6 bits (192), Expect = 5e-14
Identities = 94/381 (24%), Positives = 125/381 (32%), Gaps = 111/381 (29%)
Query: 1179 KSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC---GLGSYISG 1235
+S C N G+C +P G + C C PGF G CE D+ C PC G + S
Sbjct: 973 QSQPCHNHGTC------TPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSL 1026
Query: 1236 FHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAF 1295
+++ C C P + + E D ++Q
Sbjct: 1027 ANAFYCQCLP-------------------GHTGQWCEVEIDPCHSQ-------------- 1053
Query: 1296 TICKYPCGKSRECVAPN------ICKCKPGYIGSNCQTALCDPDCKNH-----GKCIK-- 1342
PC C A IC C G+ G C P C H G C+
Sbjct: 1054 -----PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRA--PSCGFHHCHHGGLCLPSP 1106
Query: 1343 ----PNICQCLPGHGGATC----DEEHCNP--PCQHGGTCL-------AGNLCTCPYGFV 1385
P C CL G+GG C + C P PC + G+C G C+CP+
Sbjct: 1107 KPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSP 1166
Query: 1386 GPRCETMVCNRHCENGGQCLTPDICQCKPG--WYGPTCSTALCDPVCLNGGSCNKPNTCL 1443
GPRC+ + CE D PG W G CS + DP C + C
Sbjct: 1167 GPRCQKPGA-KGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDP----WKGCPSHSRCW 1221
Query: 1444 CPNGFFGEHCQNAFCHPPCK------NGGHCMRNNVCV-CREGYTGRRFQKSICDPTCMN 1496
++ CHP C +G C C + Y F C+ C
Sbjct: 1222 L-------LFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGC-- 1272
Query: 1497 GGKCVGPSTCSCPSGWSGKRC 1517
+T C GW G C
Sbjct: 1273 -------NTAEC--GWDGGDC 1284
Score = 44.7 bits (104), Expect = 7e-04
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 26/102 (25%)
Query: 1494 CMNGGKCV----GPSTCSCPSGWSGKRCNTPICLQK---CKNGGECIA--PSICHCPSSW 1544
C NGG C+ G TC C G+ G+ C P Q C+NGG C A P+ PSS
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94
Query: 1545 EGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKIQ 1586
+ P L C+C ++G +C+ K++
Sbjct: 95 SPL-------TPSFL----------CTCLPGFTGERCQAKLE 119
>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
Length = 379
Score = 182 bits (463), Expect = 2e-45
Identities = 72/163 (44%), Positives = 91/163 (55%)
Query: 1356 TCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPG 1415
TC + C C++GG C +C CP GF GP CE +C C NGG C+TP C C PG
Sbjct: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
Query: 1416 WYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCV 1475
+YG C A C C NGG+C P C+CP G GE C+ + C PC+NGG C+ + C
Sbjct: 236 FYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCK 295
Query: 1476 CREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCN 1518
C +GY G K +C+P C G C P+ C C GW G+ CN
Sbjct: 296 CSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCN 338
Score = 171 bits (433), Expect = 5e-42
Identities = 71/167 (42%), Positives = 89/167 (53%)
Query: 1420 TCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREG 1479
TC A C C NGG CN+ C CP+GF G HC+ A C P C NGG C+ C+C G
Sbjct: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
Query: 1480 YTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICH 1539
+ G K+ C TC NGG C P C CP G G++C C Q C+NGG+CI S C
Sbjct: 236 FYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCK 295
Query: 1540 CPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKIQ 1586
C ++G C P+C P C G C PN C C+ + G C K+ +
Sbjct: 296 CSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYE 342
Score = 166 bits (420), Expect = 2e-40
Identities = 68/161 (42%), Positives = 84/161 (52%)
Query: 1389 CETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGF 1448
C+ C C NGG C IC+C G++GP C ALC P C+NGG C P C+CP GF
Sbjct: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
Query: 1449 FGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSC 1508
+G +C A C C NGG C C+C G G + + S C C NGGKC+G S C C
Sbjct: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
Query: 1509 PSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRC 1549
G+ G C+ P+C C G C P+ C C W G C
Sbjct: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337
Score = 157 bits (397), Expect = 8e-38
Identities = 63/160 (39%), Positives = 85/160 (53%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357
C C C IC+C G+ G +C+ ALC P C N G C+ P C C PG G C
Sbjct: 182 CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241
Query: 1358 DEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWY 1417
D+ +C+ C +GGTC C CP G G +CE C + C NGG+C+ C+C G+
Sbjct: 242 DKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQ 301
Query: 1418 GPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAF 1457
G CS +C+P C G+C++PN C C G+ G HC +
Sbjct: 302 GDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRY 341
Score = 148 bits (373), Expect = 5e-35
Identities = 64/163 (39%), Positives = 79/163 (48%)
Query: 1325 CQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGF 1384
CQ A C C+N G C + IC+C G G C++ C P C +GG C+ C CP GF
Sbjct: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
Query: 1385 VGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLC 1444
G C+ C+ C NGG C P C C PG G C + C C NGG C + C C
Sbjct: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
Query: 1445 PNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQK 1487
G+ G+ C C P C G C N C C+EG+ GR K
Sbjct: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
Score = 137 bits (344), Expect = 1e-31
Identities = 58/140 (41%), Positives = 73/140 (52%)
Query: 1446 NGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPST 1505
N F + CQ A C C+NGG C +C C +G+ G +K++C P CMNGG CV P
Sbjct: 170 NAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGF 229
Query: 1506 CSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCI 1565
C CP G+ G C+ C C NGG C P C CP EG +C+I C C GG+CI
Sbjct: 230 CICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCI 289
Query: 1566 FPNVCSCRTEYSGVKCEKKI 1585
+ C C Y G C K +
Sbjct: 290 GKSKCKCSKGYQGDLCSKPV 309
Score = 117 bits (292), Expect = 1e-25
Identities = 49/126 (38%), Positives = 61/126 (48%)
Query: 1297 ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGAT 1356
+C C CV P C C PG+ G NC A C C N G C P C C PG G
Sbjct: 213 LCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQ 272
Query: 1357 CDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGW 1416
C+ C PC++GG C+ + C C G+ G C VC C G C P+ CQC+ GW
Sbjct: 273 CEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGW 332
Query: 1417 YGPTCS 1422
+G C+
Sbjct: 333 HGRHCN 338
Score = 82.8 bits (203), Expect = 2e-15
Identities = 52/179 (29%), Positives = 72/179 (40%), Gaps = 55/179 (30%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCD 1242
C+NGG CV+ PG C+C PGF+G C D + C S C G + F+ C
Sbjct: 218 CMNGGLCVT-----PG----FCICPPGFYGVNC--DKANC-STTCFNGG--TCFYPGKCI 263
Query: 1243 CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPC 1302
CPP L+ E +++ C PC
Sbjct: 264 CPPGLEGEQCEISK-----------------------------------------CPQPC 282
Query: 1303 GKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEH 1361
+C+ + CKC GY G C +C+P C HG C +PN CQC G G C++ +
Sbjct: 283 RNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRY 341
Score = 42.7 bits (99), Expect = 0.003
Identities = 41/146 (28%), Positives = 49/146 (33%), Gaps = 55/146 (37%)
Query: 1180 SCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSY 1239
S C NGG+C F PG C+C PG G CE IS C PC G G
Sbjct: 247 STTCFNGGTC-----FYPGK----CICPPGLEGEQCE--ISKC-PQPCRNGGKCIG--KS 292
Query: 1240 SCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICK 1299
C C K QG KP +C+
Sbjct: 293 KCKC---------------------------------SKGYQG-DLCSKP-------VCE 311
Query: 1300 YPCGKSRECVAPNICKCKPGYIGSNC 1325
CG C PN C+C+ G+ G +C
Sbjct: 312 PGCGAHGTCHEPNKCQCQEGWHGRHC 337
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 180 bits (457), Expect = 9e-45
Identities = 96/285 (33%), Positives = 122/285 (42%), Gaps = 10/285 (3%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357
C C C+ C C G+ G +C C DC + GKC+ +C C G+ GA C
Sbjct: 190 CPGNCHLRGRCIDGQ-CICDDGFTGEDCSQLACPSDCNDQGKCVN-GVCICFEGYAGADC 247
Query: 1358 DEEHCNPPC-QHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGW 1416
E C PC + GTC+ G LC C GF G C +C +C N G+C+ + C C G+
Sbjct: 248 SREICPVPCSEEHGTCVDG-LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENE-CVCDEGF 305
Query: 1417 YGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVC 1476
G CS +C C + G C TC C GF GE C C C G C CVC
Sbjct: 306 TGEDCSELICPNDCFDRGRCIN-GTCYCEEGFTGEDCGKPTCPHACHTQGRC-EEGQCVC 363
Query: 1477 REGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPS 1536
EG+ G + C C N G+CV C C G++G C C C G C+
Sbjct: 364 DEGFAGVDCSEKRCPADCHNRGRCV-DGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQ 422
Query: 1537 ICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
C C + G C C C GRC+ C C + G C
Sbjct: 423 -CVCDEGYTGEDCSQLRCPNDCHSRGRCV-EGKCVCEQGFKGYDC 465
Score = 171 bits (433), Expect = 5e-42
Identities = 111/389 (28%), Positives = 148/389 (38%), Gaps = 41/389 (10%)
Query: 1203 LCVCLPGFHGSLCEVDI--------SGCQSNPCGLGSYISGFHSYSCDCPPELKVETQFV 1254
LCVC GF G C + C N C +G CP + + +
Sbjct: 267 LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCI 326
Query: 1255 NQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNIC 1314
N T D KPT C + C C C
Sbjct: 327 NGTCYCEEGFTGEDCG-----------------KPT-------CPHACHTQGRCEEGQ-C 361
Query: 1315 KCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLA 1374
C G+ G +C C DC N G+C+ C+C G GA C E C C G C+
Sbjct: 362 VCDEGFAGVDCSEKRCPADCHNRGRCVDGR-CECDDGFTGADCGELKCPNGCSGHGRCVN 420
Query: 1375 GNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGG 1434
G C C G+ G C + C C + G+C+ C C+ G+ G CS C C G
Sbjct: 421 GQ-CVCDEGYTGEDCSQLRCPNDCHSRGRCVEGK-CVCEQGFKGYDCSDMSCPNDCHQHG 478
Query: 1435 SCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTC 1494
C C+C +G+ GE C++ C C N G C+ + CVC +G+TG + C C
Sbjct: 479 RCVN-GMCVCDDGYTGEDCRDRQCPRDCSNRGLCV-DGQCVCEDGFTGPDCAELSCPNDC 536
Query: 1495 MNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPIC 1554
G+CV C C G+ GK C C C G C+ C C + G+ C C
Sbjct: 537 HGQGRCVN-GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQ-CICHEGFTGLDCGQHSC 594
Query: 1555 NPKCLYGGRCIFPNVCSCRTEYSGVKCEK 1583
C G+C+ C C YSG C +
Sbjct: 595 PSDCNNLGQCV-SGRCICNEGYSGEDCSE 622
Score = 170 bits (431), Expect = 9e-42
Identities = 117/402 (29%), Positives = 149/402 (37%), Gaps = 44/402 (10%)
Query: 1189 CVSDRNFSP-GSGVYLCVCLPGFHGSLC-EVDISG-------CQSNPCGLGSYISGFHSY 1239
C NFS G G CVC PG+ G C E + G C C +G
Sbjct: 161 CSGRGNFSTEGCG---CVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCS 217
Query: 1240 SCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICK 1299
CP + + + VN +D S IC
Sbjct: 218 QLACPSDCNDQGKCVNGVCICFEGYAGADCSRE------------------------ICP 253
Query: 1300 YPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDE 1359
PC + +C C G+ G +C LC +C N G+C++ N C C G G C E
Sbjct: 254 VPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVE-NECVCDEGFTGEDCSE 312
Query: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
C C G C+ G C C GF G C C C G+C C C G+ G
Sbjct: 313 LICPNDCFDRGRCINGT-CYCEEGFTGEDCGKPTCPHACHTQGRC-EEGQCVCDEGFAGV 370
Query: 1420 TCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREG 1479
CS C C N G C C C +GF G C C C G C+ N CVC EG
Sbjct: 371 DCSEKRCPADCHNRGRC-VDGRCECDDGFTGADCGELKCPNGCSGHGRCV-NGQCVCDEG 428
Query: 1480 YTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICH 1539
YTG + C C + G+CV C C G+ G C+ C C G C+ +C
Sbjct: 429 YTGEDCSQLRCPNDCHSRGRCV-EGKCVCEQGFKGYDCSDMSCPNDCHQHGRCV-NGMCV 486
Query: 1540 CPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
C + G C+ C C G C+ C C ++G C
Sbjct: 487 CDDGYTGEDCRDRQCPRDCSNRGLCV-DGQCVCEDGFTGPDC 527
Score = 130 bits (327), Expect = 1e-29
Identities = 67/175 (38%), Positives = 82/175 (46%), Gaps = 6/175 (3%)
Query: 1410 CQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCM 1469
C C+PGW GP CS C C G C C+C +GF GE C C C + G C+
Sbjct: 174 CVCEPGWKGPNCSEPECPGNCHLRGRCID-GQCICDDGFTGEDCSQLACPSDCNDQGKCV 232
Query: 1470 RNNVCVCREGYTGRRFQKSICDPTCM-NGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKN 1528
N VC+C EGY G + IC C G CV C C G++G CN P+CL C N
Sbjct: 233 -NGVCICFEGYAGADCSREICPVPCSEEHGTCV-DGLCVCHDGFAGDDCNKPLCLNNCYN 290
Query: 1529 GGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEK 1583
G C+ + C C + G C IC C GRCI C C ++G C K
Sbjct: 291 RGRCV-ENECVCDEGFTGEDCSELICPNDCFDRGRCI-NGTCYCEEGFTGEDCGK 343
Score = 129 bits (325), Expect = 2e-29
Identities = 84/316 (26%), Positives = 116/316 (36%), Gaps = 31/316 (9%)
Query: 1182 DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDI--------SGCQSNPCGLGSYI 1233
DC + G C++ C C GF G C C+ C
Sbjct: 318 DCFDRGRCINGT----------CYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGF 367
Query: 1234 SGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
+G CP + + V+ T +D K + + GR + +
Sbjct: 368 AGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDE 427
Query: 1294 AFT-------ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNIC 1346
+T C C CV C C+ G+ G +C C DC HG+C+ +C
Sbjct: 428 GYTGEDCSQLRCPNDCHSRGRCVEGK-CVCEQGFKGYDCSDMSCPNDCHQHGRCVN-GMC 485
Query: 1347 QCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLT 1406
C G+ G C + C C + G C+ G C C GF GP C + C C G+C+
Sbjct: 486 VCDDGYTGEDCRDRQCPRDCSNRGLCVDGQ-CVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
Query: 1407 PDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGG 1466
C C G+ G C C C G C C+C GF G C C C N G
Sbjct: 545 GQ-CVCHEGFMGKDCKEQRCPSDCHGQGRC-VDGQCICHEGFTGLDCGQHSCPSDCNNLG 602
Query: 1467 HCMRNNVCVCREGYTG 1482
C+ C+C EGY+G
Sbjct: 603 QCVSGR-CICNEGYSG 617
Score = 67.4 bits (163), Expect = 1e-10
Identities = 68/262 (25%), Positives = 93/262 (35%), Gaps = 42/262 (16%)
Query: 1166 CDAETRVTIEVTVKSC--DCLNGGSCVSDR------------------NFSPGSGVYL-- 1203
CD E ++ + K C DC N G CV R N G G +
Sbjct: 363 CD-EGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNG 421
Query: 1204 -CVCLPGFHGSLCEV--DISGCQSNP-CGLGSYI--SGFHSYSCD---CPPELKVETQFV 1254
CVC G+ G C + C S C G + GF Y C CP + + V
Sbjct: 422 QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCV 481
Query: 1255 NQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFT-------ICKYPCGKSRE 1307
N T D + D + +G + + FT C C
Sbjct: 482 NGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGR 541
Query: 1308 CVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQ 1367
CV C C G++G +C+ C DC G+C+ C C G G C + C C
Sbjct: 542 CVNGQ-CVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQ-CICHEGFTGLDCGQHSCPSDCN 599
Query: 1368 HGGTCLAGNLCTCPYGFVGPRC 1389
+ G C++G C C G+ G C
Sbjct: 600 NLGQCVSGR-CICNEGYSGEDC 620
Score = 63.9 bits (154), Expect = 1e-09
Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 2/112 (1%)
Query: 1474 CVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECI 1533
CVC G+ G + C C G+C+ C C G++G+ C+ C C + G+C+
Sbjct: 174 CVCEPGWKGPNCSEPECPGNCHLRGRCID-GQCICDDGFTGEDCSQLACPSDCNDQGKCV 232
Query: 1534 APSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKI 1585
+C C + G C IC C +C C ++G C K +
Sbjct: 233 N-GVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPL 283
Score = 45.8 bits (107), Expect = 3e-04
Identities = 17/33 (51%), Positives = 20/33 (60%)
Query: 886 SVLKCPNLCSGNGQCMEWGCACSPSFSSYDCSD 918
S L+CPN C G+C+E C C F YDCSD
Sbjct: 435 SQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSD 467
Score = 42.4 bits (98), Expect = 0.004
Identities = 15/30 (50%), Positives = 20/30 (66%)
Query: 888 LKCPNLCSGNGQCMEWGCACSPSFSSYDCS 917
LKCPN CSG+G+C+ C C ++ DCS
Sbjct: 406 LKCPNGCSGHGRCVNGQCVCDEGYTGEDCS 435
Score = 37.4 bits (85), Expect = 0.12
Identities = 13/31 (41%), Positives = 16/31 (51%)
Query: 888 LKCPNLCSGNGQCMEWGCACSPSFSSYDCSD 918
L CPN C G G+C+ C C F DC +
Sbjct: 530 LSCPNDCHGQGRCVNGQCVCHEGFMGKDCKE 560
Score = 36.2 bits (82), Expect = 0.26
Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 22/121 (18%)
Query: 807 LTLCQETLANSSIGR-LCLAFLGKRLDSVIEMCVKDVLLKDDLSWAEAGVALLENECEKR 865
L +C + A + LCL R V CV D + + + + N+C R
Sbjct: 267 LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCD----EGFTGEDCSELICPNDCFDR 322
Query: 866 --------IVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDCS 917
EEG + E+ G CP+ C G+C E C C F+ DCS
Sbjct: 323 GRCINGTCYCEEG-FTGEDCGKPT--------CPHACHTQGRCEEGQCVCDEGFAGVDCS 373
Query: 918 D 918
+
Sbjct: 374 E 374
Score = 36.2 bits (82), Expect = 0.26
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 860 NECEKR-IVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDCSD 918
N+C R EGK E+ + S + CPN C +G+C+ C C ++ DC D
Sbjct: 441 NDCHSRGRCVEGKCVCEQGFKGYD--CSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRD 498
Query: 919 SYDKAPEITELGNAGFC 935
+ P + N G C
Sbjct: 499 R--QCPR--DCSNRGLC 511
Score = 35.4 bits (80), Expect = 0.44
Identities = 11/28 (39%), Positives = 17/28 (60%)
Query: 889 KCPNLCSGNGQCMEWGCACSPSFSSYDC 916
+CP+ C G G+C++ C C F+ DC
Sbjct: 562 RCPSDCHGQGRCVDGQCICHEGFTGLDC 589
Score = 35.4 bits (80), Expect = 0.44
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDCSD 918
CP+ C+ GQC+ C C+ +S DCS+
Sbjct: 594 CPSDCNNLGQCVSGRCICNEGYSGEDCSE 622
Score = 34.3 bits (77), Expect = 0.99
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 2/52 (3%)
Query: 886 SVLKCPNLCSGNGQCMEWGCACSPSFSSYDCSDSYDKAPEITELGNA--GFC 935
S L CP+ C+ G+C+ C C ++ DCS P E G G C
Sbjct: 217 SQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLC 268
Score = 34.3 bits (77), Expect = 0.99
Identities = 11/30 (36%), Positives = 17/30 (56%)
Query: 889 KCPNLCSGNGQCMEWGCACSPSFSSYDCSD 918
+CP CS G C++ C C F+ DC++
Sbjct: 500 QCPRDCSNRGLCVDGQCVCEDGFTGPDCAE 529
Score = 33.9 bits (76), Expect = 1.3
Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 868 EEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDCSD 918
EEG+ +E ++ S +CP C G+C++ C C F+ DC +
Sbjct: 357 EEGQCVCDEGFAGVD--CSEKRCPADCHNRGRCVDGRCECDDGFTGADCGE 405
Score = 33.1 bits (74), Expect = 2.2
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 5/53 (9%)
Query: 870 GKYNTEEYGTSIED-----ILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDCS 917
G ++TE G E S +CP C G+C++ C C F+ DCS
Sbjct: 165 GNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCS 217
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 179 bits (454), Expect = 2e-44
Identities = 143/470 (30%), Positives = 203/470 (43%), Gaps = 84/470 (17%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C NGG+C G Y C CLPGF G CEV++ C + C G+ + G ++Y+C
Sbjct: 206 CRNGGTCRQS-----GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
Query: 1242 DCPPELKVETQFVNQFTTQTV-VLTRSDKSVNKEEDDKNAQGRKRHV-------KPTSGN 1293
CPPE + QF T+ V + + N G V + S N
Sbjct: 261 QCPPE------WTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQN 314
Query: 1294 AFTICKYPCGKSREC---VAPNICKCKPGYIGSNC------------QTALCDPDCKNHG 1338
C C VA C C G G C + A+CD + N G
Sbjct: 315 IDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVN-G 373
Query: 1339 KCIKPNICQCLPGHGGATCDE--EHCN---PPCQHGGTCL---AGNLCTCPYGFVGPRCE 1390
+ IC C PG G CD+ + C+ PC+H G C+ LC C G+ GPRCE
Sbjct: 374 RA----ICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE 429
Query: 1391 TMV---CNRHCENGGQCLT---PDICQCKPGWYGPTCSTALCD---PVCLNGGSC-NKPN 1440
T V + C N CL C C G+ G C + + C+NGG C ++ N
Sbjct: 430 TDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVN 489
Query: 1441 --TCLCPNGFFGEHCQ---NAFCHPPCKNGGHCM---RNNVCVCREGYTGRRFQKSI--C 1490
+C CP+GF G CQ + PC+NG C+ C C EG+ G +++ C
Sbjct: 490 GFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDC 549
Query: 1491 DPTCMNGGKCV---GPSTCSCPSGWSGKRCNTPI--C-LQKCKNGGEC---IAPSICHCP 1541
P + G+CV +C+C G++G RC + + C Q C++GG+C + +C CP
Sbjct: 550 SPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP 609
Query: 1542 SSWEGVRCQIPI----CNPKCLYG--GRCIFPNVCSCRTEYSGVKCEKKI 1585
S GV C++ I NP C +G I C C+ ++G C +I
Sbjct: 610 SGTTGVNCEVNIDDCASNP-CTFGVCRDGINRYDCVCQPGFTGPLCNVEI 658
Score = 176 bits (447), Expect = 1e-43
Identities = 140/471 (29%), Positives = 192/471 (40%), Gaps = 74/471 (15%)
Query: 1173 TIEVTVKSC---DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGL 1229
T ++ V C C NG CV + Y C C GF G+LC+ ++ C +PC
Sbjct: 503 TCQLDVDECASTPCRNGAKCVDQPDG------YECRCAEGFEGTLCDRNVDDCSPDPCHH 556
Query: 1230 GSYISGFHSYSCDCPP---ELKVETQFVNQFTTQTV-----VLTRSDKSVNKEEDDKNAQ 1281
G + G S+SC C P + E+Q V++ +Q L DK + +
Sbjct: 557 GRCVDGIASFSCACAPGYTGTRCESQ-VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGV 615
Query: 1282 GRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL---CDPDCKNHG 1338
+ ++ + N T G R+ + C C+PG+ G C + C G
Sbjct: 616 NCEVNIDDCASNPCTF-----GVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGG 670
Query: 1339 KCIKPN---ICQCLPGHGGATC---DEEHCNPPCQHGGTCL---AGNLCTCPYGFVGPRC 1389
C+ C C PG C + PC H G C G C C G+ GPRC
Sbjct: 671 SCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSH-GICYDAPGGFRCVCEPGWSGPRC 729
Query: 1390 ETMVCNRHCEN-----GGQCLTPDI---CQCKPGWYGPTCS-TALCDP-VCLNGGSCNKP 1439
+ CE+ GG C + + C C PG G C + C P C +GG C
Sbjct: 730 SQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESA 789
Query: 1440 ----NTCLCPNGFFGEHCQNAF--CHPPCKNGGHCMRNNV-----CVCREGYTGRRFQKS 1488
C CP G+ G CQ C P G H + N+ C C GYTG +
Sbjct: 790 PGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQD 849
Query: 1489 I--CDPT-CMNGGKC---VGPSTCSCPSGWSGKRCNTPI--CLQKCKNGGEC---IAPSI 1537
I CDP C+NGG C VG +CSC G++G RC + CL G C +A
Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFT 909
Query: 1538 CHCPSSWEGVRCQ--IPICNP-KCLYGGRC---IFPNVCSCRTEYSGVKCE 1582
C CP + G C+ +P C+P C GG C + C CR Y+G C+
Sbjct: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ 960
Score = 176 bits (446), Expect = 2e-43
Identities = 134/456 (29%), Positives = 188/456 (41%), Gaps = 91/456 (19%)
Query: 1182 DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISG-FHSYS 1240
+CL+G C + G + C+C+ GF G+ CEVDI CQS+PC G + +S
Sbjct: 434 ECLSG-PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 492
Query: 1241 CDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKY 1300
C CP + F+ T L +
Sbjct: 493 CTCP----------SGFSGSTCQLDVDE----------------------------CAST 514
Query: 1301 PCGKSRECV-APN--ICKCKPGYIGSNCQTAL--CDPDCKNHGKC---IKPNICQCLPGH 1352
PC +CV P+ C+C G+ G+ C + C PD +HG+C I C C PG+
Sbjct: 515 PCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGY 574
Query: 1353 GGATCD---EEHCNPPCQHGGTCL---AGNLCTCPYGFVGPRCETMV--CNRHCENGGQC 1404
G C+ +E + PC+HGG CL LC CP G G CE + C + G C
Sbjct: 575 TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVC 634
Query: 1405 ---LTPDICQCKPGWYGPTCSTAL---CDPVCLNGGSC---NKPNTCLCPNGFFGEHC-- 1453
+ C C+PG+ GP C+ + C GGSC CLCP G C
Sbjct: 635 RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP 694
Query: 1454 -QNAFCHPPCKNG--GHCMRNNVCVCREGYTGRRFQKSICDPTCMN-----GGKCVGPST 1505
+ H PC +G CVC G++G R +S+ C + GG C
Sbjct: 695 PSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM 754
Query: 1506 ---CSCPSGWSGKRCN--TPICLQKCKNGGEC-IAPS---ICHCPSSWEGVRCQ--IPIC 1554
C+CP G G++C +P C++GG C AP +C CP W+G RCQ + C
Sbjct: 755 GFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDEC 814
Query: 1555 NPKCLYGGRCIFPNV-----CSCRTEYSGVKCEKKI 1585
G I N+ C+C Y+G C++ I
Sbjct: 815 AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDI 850
Score = 172 bits (437), Expect = 2e-42
Identities = 135/456 (29%), Positives = 182/456 (39%), Gaps = 113/456 (24%)
Query: 1199 SGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSCDCPPELKVETQFVNQF 1257
+G + C C G+ G C+ DI+ C NPC GS G S+SC C P F
Sbjct: 830 AGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPG------FAGPR 883
Query: 1258 TTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSR--ECVAPNICK 1315
+ V D+ ++ PCG + VA C
Sbjct: 884 CARDV-----DECLSN---------------------------PCGPGTCTDHVASFTCT 911
Query: 1316 CKPGYIGSNCQTAL--CDPD-CKNHGKCI---KPNICQCLPGHGGATCDEEH---CNPPC 1366
C PGY G +C+ L C P C N G C+ C C PG+ GA C E + PC
Sbjct: 912 CPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPC 971
Query: 1367 QHGGTCLA---GNLCTCPYGFVGPRCETMV--CNRH-CENGGQCL-TPDICQCKPGWYGP 1419
HGG C A G CTC F GP+C+T+V C+R C+NGG+C+ T C C PGW G
Sbjct: 972 LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGR 1031
Query: 1420 TCST-------------ALCDPVCLNGGSC---NKPNTCLCPNGFFGEHCQ---NAFCHP 1460
C + +C GG C + + C+CP G G HC+ +
Sbjct: 1032 LCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQ 1091
Query: 1461 PCKNGGHC---MRNNVCVCREGYTGRRFQKSI---CDPTCMNGGKC---VGPSTCSCPSG 1511
PC++GG C M +C C GY G + + C +GG C V CSCP G
Sbjct: 1092 PCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPG 1151
Query: 1512 WSGKRC--NTPIC--------LQKCKNGGEC---IAPSICHCPSSWEGVRCQIPICNPKC 1558
G C N C +C + G C + C CP + G+RC+ I +
Sbjct: 1152 TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECR- 1210
Query: 1559 LYGGRCIFPNV------------CSCRTEYSGVKCE 1582
G C + C C +SG +C+
Sbjct: 1211 --SGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQ 1244
Score = 150 bits (378), Expect = 1e-35
Identities = 128/488 (26%), Positives = 194/488 (39%), Gaps = 102/488 (20%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFH-SYSC 1241
C NGG+CV G + C+C PG+ G+ C+ + C S PC G S H + C
Sbjct: 933 CFNGGTCVD------GVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRC 986
Query: 1242 DC-----PPELKVETQFVNQFTTQT---VVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
C P+ + + ++ Q V T + + R + +
Sbjct: 987 TCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQ 1046
Query: 1294 AFTICKYPCGKSRECV---APNICKCKPGYIGSNCQTALCDP----DCKNHGKC---IKP 1343
+ C +CV + + C C G GS+C+ + DP C++ G C +
Sbjct: 1047 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEV-DPCLAQPCQHGGTCRGYMGG 1105
Query: 1344 NICQCLPGHGGATCD---EEHCNPPCQHGGTCL---AGNLCTCPYGFVGPRCE------- 1390
+C+CLPG+ G C+ +E + PCQHGG+C+ A LC+CP G +G CE
Sbjct: 1106 YMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCG 1165
Query: 1391 ---TMVCNRHCENGGQCLTPDI-----CQCKPGWYGPTCSTALCDPVCLNGGSCNKPNT- 1441
+ C + G C+ D+ C C PG+ G C + + G+C+ +T
Sbjct: 1166 PGPPLDSGPRCLHNGTCV--DLVGGFRCTCPPGYTGLRCEADINE---CRSGACHAAHTR 1220
Query: 1442 -----------CLCPNGFFGEHCQNAFC---HPPCKNGGHCMRNN--------VCVCREG 1479
CLC GF G CQ PC++GG C + C C +
Sbjct: 1221 DCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1280
Query: 1480 YTG---RRFQKSICDPTCMNGGKCV----GPSTCSCPSGWSGKRC-----------NTPI 1521
+ G R +S + C G C GP C+CP G SG C N
Sbjct: 1281 FWGPRCERVARSCRELQCPVGVPCQQTPRGP-RCACPPGLSGPSCRSFPGSPPGASNASC 1339
Query: 1522 CLQKCKNGGEC----IAPSI-CHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEY 1576
C +GG C +AP C C W G RC+ P P+ RC P +C+ +
Sbjct: 1340 AAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRC--PR-AACQAKR 1396
Query: 1577 SGVKCEKK 1584
+C+++
Sbjct: 1397 GDQRCDRE 1404
Score = 146 bits (368), Expect = 2e-34
Identities = 139/502 (27%), Positives = 190/502 (37%), Gaps = 147/502 (29%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLG----SYISGFH 1237
C NGG C S C+C PG+ G C+++ C S PC G G S ++G
Sbjct: 49 CANGGRCTQ-----LPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTA 102
Query: 1238 SYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTI 1297
+SC CP + P
Sbjct: 103 RFSCRCPRGFR---------------------------------------GPDCSLPDPC 123
Query: 1298 CKYPCGKSREC-VAPN---ICKCKPGYIGSNCQTALCD----PDCKNHGKCIKPN---IC 1346
PC C V P+ +C C PGY G +C++ + + C++ G C+ C
Sbjct: 124 LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRC 183
Query: 1347 QCLPGHGGATCDEE--HCNP-PCQHGGTC-LAGNL---CTCPYGFVGPRCETMV--CNRH 1397
QC G+ G C+ C P PC++GGTC +G+L C C GF G CE V C H
Sbjct: 184 QCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGH 243
Query: 1398 -CENGGQC---LTPDICQCKPGWYGPTCS-----TALCDPVCLNGGSCNKP---NTCLCP 1445
C NGG C + CQC P W G C+ L C NGG+C ++C+C
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCV 303
Query: 1446 NGFFGEHC-------------QNAFCHP---------------------------PCKNG 1465
NG+ GE C A CH PC
Sbjct: 304 NGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHED 363
Query: 1466 GHCMRNNV-----CVCREGYTGRRFQK-----SICDPTCMNGGKCV---GPSTCSCPSGW 1512
C N V C C G+TG + SI C + G+CV G C C G+
Sbjct: 364 AICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY 423
Query: 1513 SGKRCNTPI--CLQ-KCKNGGEC---IAPSICHCPSSWEGVRCQIPI--C-NPKCLYGGR 1563
+G RC T + CL C+N C I C C + + G C++ I C + C+ GG
Sbjct: 424 TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV 483
Query: 1564 C---IFPNVCSCRTEYSGVKCE 1582
C + C+C + +SG C+
Sbjct: 484 CKDRVNGFSCTCPSGFSGSTCQ 505
Score = 140 bits (352), Expect = 1e-32
Identities = 108/331 (32%), Positives = 146/331 (44%), Gaps = 63/331 (19%)
Query: 1314 CKCKPGYIGSNCQTALCDP----DCKNHGKC-IKPN---ICQCLPGHGGATC----DEEH 1361
C+C G+ G +C +L DP C + +C + P+ +C C PG+ G +C DE
Sbjct: 106 CRCPRGFRGPDC--SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECR 163
Query: 1362 CNPPCQHGGTCL---AGNLCTCPYGFVGPRCETMV---CNRHCENGGQC-----LTPDIC 1410
PC+HGGTCL C CP G+ GP CE C NGG C LT D C
Sbjct: 164 VGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYD-C 222
Query: 1411 QCKPGWYGPTCSTALCD---PVCLNGGSC-NKPNT--CLCPNGFFGEHCQNAF--CH--- 1459
C PG+ G C + D CLNGG+C + NT C CP + G+ C C
Sbjct: 223 ACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQP 282
Query: 1460 PPCKNGGHC---MRNNVCVCREGYTGRRFQKSICD---PTCMNGGKC---VGPSTCSCPS 1510
C NGG C + + CVC G+TG ++I D C +G C V C+CP
Sbjct: 283 NACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPM 342
Query: 1511 GWSGKRCN-TPICLQK-CKNGGEC-----IAPSICHCPSSWEGVRCQIPI------CNPK 1557
G +G C+ C+ C C +IC CP + G C + NP
Sbjct: 343 GKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANP- 401
Query: 1558 CLYGGRCIFPN---VCSCRTEYSGVKCEKKI 1585
C + GRC+ +C C Y+G +CE +
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDV 432
Score = 138 bits (348), Expect = 4e-32
Identities = 129/503 (25%), Positives = 180/503 (35%), Gaps = 141/503 (28%)
Query: 1180 SCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQ-SNPCGL-GSYISGFH 1237
S C +G C + P G +LC C PG+ G C D+ C+ PC G+ ++
Sbjct: 125 SSPCAHGARC----SVGP-DGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPG 179
Query: 1238 SYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTI 1297
S+ C CP + P N
Sbjct: 180 SFRCQCP---------------------------------------AGYTGPLCENPAVP 200
Query: 1298 C-KYPCGKSRECVAPN----ICKCKPGYIGSNCQTALCD---PDCKNHGKC---IKPNIC 1346
C PC C C C PG+ G NC+ + D C N G C + C
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
Query: 1347 QCLPGHGGATC--DEEHCN---PPCQHGGTC---LAGNLCTCPYGFVGPRCETMV---CN 1395
QC P G C D + C C +GGTC L G+ C C G+ G C +
Sbjct: 261 QCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT 320
Query: 1396 RHCENGGQC---LTPDICQCKPGWYGPTC------------STALCD------------P 1428
C +G C + C C G G C A+CD P
Sbjct: 321 AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCP 380
Query: 1429 VCLNGGSCNKP------------------NT-----CLCPNGFFGEHCQ---NAFCHPPC 1462
GG+C++ NT C C G+ G C+ N PC
Sbjct: 381 PGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC 440
Query: 1463 KNGGHCM---RNNVCVCREGYTGRRFQKSI--CDPT-CMNGGKC---VGPSTCSCPSGWS 1513
+N C+ C+C G+TG + I C + C+NGG C V +C+CPSG+S
Sbjct: 441 RNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFS 500
Query: 1514 GKRCNTPI---CLQKCKNGGECIAPS---ICHCPSSWEGVRC--QIPICNPKCLYGGRC- 1564
G C + C+NG +C+ C C +EG C + C+P + GRC
Sbjct: 501 GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCV 560
Query: 1565 --IFPNVCSCRTEYSGVKCEKKI 1585
I C+C Y+G +CE ++
Sbjct: 561 DGIASFSCACAPGYTGTRCESQV 583
Score = 129 bits (325), Expect = 2e-29
Identities = 129/469 (27%), Positives = 174/469 (37%), Gaps = 109/469 (23%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCD 1242
CL+GG C + PG + C CL F G C+ + C PC G +Y C
Sbjct: 971 CLHGGVCSAAH---PG---FRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY-CL 1023
Query: 1243 CPP-------------------ELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGR 1283
CPP ++ V + + Q Q V S V E +
Sbjct: 1024 CPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPE--GRTGSHC 1081
Query: 1284 KRHVKPTSGNAFTICKYPC---GKSRECVAPNICKCKPGYIGSNCQTAL---CDPDCKNH 1337
++ V P PC G R + +C+C PGY G NC+ + C++
Sbjct: 1082 EQEVDPCLAQ-------PCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHG 1134
Query: 1338 GKCIK---PNICQCLPGHGGATCD--EEHCNPP--------CQHGGTCL---AGNLCTCP 1381
G CI +C C PG G C+ E+ C P C H GTC+ G CTCP
Sbjct: 1135 GSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1194
Query: 1382 YGFVGPRCETMVCNRHCENGG-------QCLTPD----ICQCKPGWYGPTCSTAL--CDP 1428
G+ G RCE + C +G CL C C G+ GP C T L C+
Sbjct: 1195 PGYTGLRCEADI--NECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
Query: 1429 V-CLNGGSCNKPN---------TCLCPNGFFGEHCQNAF--CHP-PCKNGGHCM---RNN 1472
C +GG C +P+ TC C F+G C+ C C G C R
Sbjct: 1253 QPCQHGGQC-RPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGP 1311
Query: 1473 VCVCREGYTG---RRF--------QKSICDPTCMNGGKC----VGPS-TCSCPSGWSGKR 1516
C C G +G R F S C++GG C + P C+C GW+G R
Sbjct: 1312 RCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPR 1371
Query: 1517 CNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLY-GGRC 1564
C P + C + C + RC +P C + GG C
Sbjct: 1372 CEAPAAAPEVSEEPRCPRAA---CQAKRGDQRCDRECNSPGCGWDGGDC 1417
Score = 108 bits (271), Expect = 3e-23
Identities = 87/309 (28%), Positives = 124/309 (40%), Gaps = 91/309 (29%)
Query: 1364 PPCQHGGTCLAGNLCT----------CPYGFVGPRCETM------------VC------- 1394
PPC G C G CT CP G+VG RC+ VC
Sbjct: 41 PPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAG 100
Query: 1395 ------------------------NRHCENGGQC-LTPD---ICQCKPGWYGPTCSTALC 1426
+ C +G +C + PD +C C PG+ G +C + +
Sbjct: 101 TARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD 160
Query: 1427 D----PVCLNGGSC-NKPNT--CLCPNGFFGEHCQNAF--CHP-PCKNGGHCMRNN---- 1472
+ C +GG+C N P + C CP G+ G C+N C P PC+NGG C ++
Sbjct: 161 ECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTY 220
Query: 1473 VCVCREGYTGRRFQKSICD---PTCMNGGKCV-GPST--CSCPSGWSGKRCNTPI--CL- 1523
C C G+ G+ + ++ D C+NGG CV G +T C CP W+G+ C + C
Sbjct: 221 DCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQL 280
Query: 1524 --QKCKNGGEC---IAPSICHCPSSWEGVRCQIPI---CNPKCLYGGRC---IFPNVCSC 1572
C NGG C + C C + W G C I C +G C + C+C
Sbjct: 281 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 340
Query: 1573 RTEYSGVKC 1581
+G+ C
Sbjct: 341 PMGKTGLLC 349
Score = 102 bits (255), Expect = 2e-21
Identities = 120/451 (26%), Positives = 153/451 (33%), Gaps = 127/451 (28%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLG-SYISGFHSYSC 1241
C +GG+C R + G Y+C CLPG++G CE D+ C S PC G S I Y C
Sbjct: 1093 CQHGGTC---RGYMGG---YMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLC 1146
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
CPP +N+ D G P C +
Sbjct: 1147 SCPPGTLGVLCEINE--------------------DDCGPGPPLDSGPR-------CLHN 1179
Query: 1302 CGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGA---TCD 1358
G + V C C PGY G C+ + +C++ G C + CL GG C
Sbjct: 1180 -GTCVDLVGGFRCTCPPGYTGLRCEADI--NECRS-GACHAAHTRDCLQDPGGGFRCLCH 1235
Query: 1359 EEHCNP------------PCQHGGTCL-----AGNL---CTCPYGFVGPRCETMV--CNR 1396
P PCQHGG C G L C C F GPRCE + C
Sbjct: 1236 AGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRE 1295
Query: 1397 -HCENGGQCL-TP--DICQCKPGWYGPTC----------STALCDPV-CLNGGSCNKPNT 1441
C G C TP C C PG GP+C S A C CL+GGSC
Sbjct: 1296 LQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPL 1355
Query: 1442 -----CLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREG----------------- 1479
C C G+ G C+ P C R C + G
Sbjct: 1356 APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRA-ACQAKRGDQRCDRECNSPGCGWDG 1414
Query: 1480 -----------------YTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPIC 1522
R F S CDP C + C+ C +G + CN P+
Sbjct: 1415 GDCSLSVGDPWRQCEALQCWRLFNNSRCDPAC-SSPACL-YDNFDCHAGGRERTCN-PVY 1471
Query: 1523 LQKCKN---GGECIAPSICHCPS-SWEGVRC 1549
+ C + G C C+ W+G+ C
Sbjct: 1472 EKYCADHFADGRC--DQGCNTEECGWDGLDC 1500
Score = 90.1 bits (222), Expect = 2e-17
Identities = 68/207 (32%), Positives = 90/207 (43%), Gaps = 40/207 (19%)
Query: 1414 PGWYGPTCSTALCDPVCLNGGSC----NKPNTCLCPNGFFGEHCQ-NAFCHP-PCKNGGH 1467
PG P C L C NGG C ++ CLCP G+ GE CQ CH PC G
Sbjct: 36 PGAAAPPC---LDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGV 92
Query: 1468 CMRNNV-------CVCREGYTGRRFQKSICDP----TCMNGGKC-VGPS---TCSCPSGW 1512
C + V C C G+ G S+ DP C +G +C VGP CSCP G+
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGP--DCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY 150
Query: 1513 SGKRCNTPI--CL--QKCKNGGECI---APSICHCPSSWEGVRCQIPI--CNPK-CLYGG 1562
G+ C + + C + C++GG C+ C CP+ + G C+ P C P C GG
Sbjct: 151 QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGG 210
Query: 1563 RC----IFPNVCSCRTEYSGVKCEKKI 1585
C C+C + G CE +
Sbjct: 211 TCRQSGDLTYDCACLPGFEGQNCEVNV 237
Score = 65.1 bits (157), Expect = 5e-10
Identities = 89/389 (22%), Positives = 121/389 (31%), Gaps = 119/389 (30%)
Query: 1166 CDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSN 1225
C+A+ E +C + C+ D PG G + C+C GF G C+ +S C+S
Sbjct: 1202 CEADIN---ECRSGACHAAHTRDCLQD----PGGG-FRCLCHAGFSGPRCQTVLSPCESQ 1253
Query: 1226 PCGLGSYI------SGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKN 1279
PC G G +++C C Q R ++ + +
Sbjct: 1254 PCQHGGQCRPSPGPGGGLTFTCHC---------------AQPFWGPRCERVARSCRELQC 1298
Query: 1280 AQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGK 1339
G PC ++ P C C PG G +C++ P
Sbjct: 1299 PVG-----------------VPCQQTPR--GPR-CACPPGLSGPSCRSFPGSP------- 1331
Query: 1340 CIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNL-----CTCPYGFVGPRCETMVC 1394
PG A+C PC HGG+C L C C G+ GPRCE
Sbjct: 1332 ----------PGASNASC----AAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAA 1377
Query: 1395 NRHCENGGQCLTPDICQCKP--------------GWYGPTCSTALCDPVCLNGGSCNKPN 1440
+C CQ K GW G CS ++ DP +
Sbjct: 1378 APEVSEEPRC-PRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDP-------WRQCE 1429
Query: 1441 TCLCPNGFFGEHCQNAFCHP-------PCKNGGHCMRNNVC-VCREGYTGRRFQKSICDP 1492
C F C A P C GG R C E Y F CD
Sbjct: 1430 ALQCWRLFNNSRCDPACSSPACLYDNFDCHAGG---RERTCNPVYEKYCADHFADGRCDQ 1486
Query: 1493 TCMNGGKCVGPSTCSCPSGWSGKRCNTPI 1521
C N +C GW G C + +
Sbjct: 1487 GC-NTEEC----------GWDGLDCASEV 1504
Score = 34.7 bits (78), Expect = 0.76
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 8/59 (13%)
Query: 891 PNLCSGNGQCMEWG-----CACSPSFSSYDCSDSYDKAPEITELGNAGFC--DVQKYNC 942
P+ C G C + G CAC P F +C + D P L N G C V YNC
Sbjct: 203 PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCL-NGGTCVDGVNTYNC 260
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 172 bits (436), Expect = 2e-42
Identities = 95/284 (33%), Positives = 113/284 (39%), Gaps = 9/284 (3%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357
C C CV C C PGY G +C C DC+ G+C++ +C C G G C
Sbjct: 187 CPDDCNDQGRCVRGR-CVCFPGYTGPSCGWPSCPGDCQGRGRCVQ-GVCVCRAGFSGPDC 244
Query: 1358 DEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWY 1417
+ C C G C G C C G+ G C C R C G+C C C PG+
Sbjct: 245 SQRSCPRGCSQRGRC-EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRC-ENGRCVCNPGYT 302
Query: 1418 GPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCR 1477
G C C C G C K C+C G+ GE C C C GG C+ + CVC
Sbjct: 303 GEDCGVRSCPRGCSQRGRC-KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCV-DGRCVCW 360
Query: 1478 EGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSI 1537
GYTG C C G+C C C +G+SG C C C G C
Sbjct: 361 PGYTGEDCSTRTCPRDCRGRGRC-EDGECICDTGYSGDDCGVRSCPGDCNQRGRC-EDGR 418
Query: 1538 CHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
C C + G C C C GRC VC C YSG C
Sbjct: 419 CVCWPGYTGTDCGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDC 461
Score = 171 bits (433), Expect = 5e-42
Identities = 118/415 (28%), Positives = 155/415 (37%), Gaps = 34/415 (8%)
Query: 1182 DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDIS--GC-QSNPCGLGSYIS--GF 1236
DC G CV +CVC GF G C GC Q C G + G+
Sbjct: 221 DCQGRGRCVQG----------VCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGY 270
Query: 1237 HSYSC---DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
C CP + N T D V + +GR + +
Sbjct: 271 TGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDP 330
Query: 1294 AFT-------ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNIC 1346
+T C + CG+ CV C C PGY G +C T C DC+ G+C + C
Sbjct: 331 GYTGEDCGTRSCPWDCGEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRC-EDGEC 388
Query: 1347 QCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLT 1406
C G+ G C C C G C G C C G+ G C + C R C G+C
Sbjct: 389 ICDTGYSGDDCGVRSCPGDCNQRGRCEDGR-CVCWPGYTGTDCGSRACPRDCRGRGRC-E 446
Query: 1407 PDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGG 1466
+C C G+ G C C C G C + C+C G+ G C C C+ G
Sbjct: 447 NGVCVCNAGYSGEDCGVRSCPGDCRGRGRC-ESGRCMCWPGYTGRDCGTRACPGDCRGRG 505
Query: 1467 HCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKC 1526
C+ + CVC G+TG C C G C C C +G+SG+ C+T C C
Sbjct: 506 RCV-DGRCVCNPGFTGEDCGSRRCPGDCRGHGLC-EDGVCVCDAGYSGEDCSTRSCPGGC 563
Query: 1527 KNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
+ G+C+ C C + G C + C C G C VC C Y C
Sbjct: 564 RGRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQHGVC-QDGVCICWEGYVSEDC 616
Score = 167 bits (424), Expect = 6e-41
Identities = 92/283 (32%), Positives = 120/283 (42%), Gaps = 23/283 (8%)
Query: 1314 CKCKPGYIGSNCQ---------------TALCDPDCKNHGKCIKPNICQCLPGHGGATCD 1358
C C+PG+ G C + C DC + G+C++ C C PG+ G +C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGR-CVCFPGYTGPSCG 214
Query: 1359 EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYG 1418
C CQ G C+ G +C C GF GP C C R C G+C C C PG+ G
Sbjct: 215 WPSCPGDCQGRGRCVQG-VCVCRAGFSGPDCSQRSCPRGCSQRGRC-EGGRCVCDPGYTG 272
Query: 1419 PTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCRE 1478
C C C G C C+C G+ GE C C C G C ++ CVC
Sbjct: 273 DDCGMRSCPRGCSQRGRCEN-GRCVCNPGYTGEDCGVRSCPRGCSQRGRC-KDGRCVCDP 330
Query: 1479 GYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSIC 1538
GYTG C C GG+CV C C G++G+ C+T C + C+ G C C
Sbjct: 331 GYTGEDCGTRSCPWDCGEGGRCV-DGRCVCWPGYTGEDCSTRTCPRDCRGRGRC-EDGEC 388
Query: 1539 HCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
C + + G C + C C GRC C C Y+G C
Sbjct: 389 ICDTGYSGDDCGVRSCPGDCNQRGRC-EDGRCVCWPGYTGTDC 430
Score = 167 bits (423), Expect = 7e-41
Identities = 119/428 (27%), Positives = 155/428 (36%), Gaps = 39/428 (9%)
Query: 1179 KSC--DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEV-----DISG---CQSNPCG 1228
+SC DC GG CV R CVC PG+ G C D G C+ C
Sbjct: 340 RSCPWDCGEGGRCVDGR----------CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI 389
Query: 1229 LGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVK 1288
+ SG CP + + + T +D D +GR +
Sbjct: 390 CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGV 449
Query: 1289 PTSGNAFT-------ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCI 1341
++ C C C + C C PGY G +C T C DC+ G+C+
Sbjct: 450 CVCNAGYSGEDCGVRSCPGDCRGRGRCESGR-CMCWPGYTGRDCGTRACPGDCRGRGRCV 508
Query: 1342 KPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENG 1401
C C PG G C C C+ G C G +C C G+ G C T C C
Sbjct: 509 DGR-CVCNPGFTGEDCGSRRCPGDCRGHGLCEDG-VCVCDAGYSGEDCSTRSCPGGCRGR 566
Query: 1402 GQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPP 1461
GQCL C C+ G+ G C C C G C + C+C G+ E C C
Sbjct: 567 GQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQHGVC-QDGVCICWEGYVSEDCSIRTCPSN 624
Query: 1462 CKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPI 1521
C G C C+C GYTG +C C G+CV C C G+ G+ C
Sbjct: 625 CHGRGRCEEGR-CLCDPGYTGPTCATRMCPADCRGRGRCV-QGVCLCHVGYGGEDCGQEE 682
Query: 1522 CLQKCKNGG----ECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYS 1577
GG E C C + G C I C C G C C C+ Y+
Sbjct: 683 PPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGEC-HDGSCVCKDGYA 741
Query: 1578 GVKCEKKI 1585
G C +++
Sbjct: 742 GEDCGEEV 749
Score = 144 bits (362), Expect = 9e-34
Identities = 89/287 (31%), Positives = 112/287 (39%), Gaps = 27/287 (9%)
Query: 1315 KCKPGYIGSNCQTALCDPD----CKNHGKC-IKPNICQCLPGHGGATCDEE--------- 1360
+C G ++ Q D C HG + C C PG GG TC +
Sbjct: 120 QCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSS 179
Query: 1361 ------HCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKP 1414
C C G C+ G C C G+ GP C C C+ G+C+ +C C+
Sbjct: 180 PPSASGSCPDDCNDQGRCVRGR-CVCFPGYTGPSCGWPSCPGDCQGRGRCV-QGVCVCRA 237
Query: 1415 GWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVC 1474
G+ GP CS C C G C + C+C G+ G+ C C C G C N C
Sbjct: 238 GFSGPDCSQRSCPRGCSQRGRC-EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRC-ENGRC 295
Query: 1475 VCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIA 1534
VC GYTG C C G+C C C G++G+ C T C C GG C+
Sbjct: 296 VCNPGYTGEDCGVRSCPRGCSQRGRC-KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCV- 353
Query: 1535 PSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
C C + G C C C GRC C C T YSG C
Sbjct: 354 DGRCVCWPGYTGEDCSTRTCPRDCRGRGRC-EDGECICDTGYSGDDC 399
Score = 57.8 bits (138), Expect = 8e-08
Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 20/119 (16%)
Query: 1481 TGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPI---------------CLQK 1525
TG+ +++C ++G + TCSC GW G C+ P C
Sbjct: 134 TGQTDVRTLCS---LHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDD 190
Query: 1526 CKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKK 1584
C + G C+ C C + G C P C C GRC+ VC CR +SG C ++
Sbjct: 191 CNDQGRCVR-GRCVCFPGYTGPSCGWPSCPGDCQGRGRCV-QGVCVCRAGFSGPDCSQR 247
Score = 40.0 bits (92), Expect = 0.018
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 845 KDDLSWAEAGVALLENECEKR-IVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCMEW 903
+D S + GV N+C + + ++G E G ED S+ CP+ C G G+C E
Sbjct: 577 EDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWE-GYVSEDC-SIRTCPSNCHGRGRCEEG 634
Query: 904 GCACSPSFSSYDCS 917
C C P ++ C+
Sbjct: 635 RCLCDPGYTGPTCA 648
Score = 38.1 bits (87), Expect = 0.068
Identities = 12/27 (44%), Positives = 17/27 (62%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC 916
CP C G G+C++ C C+P F+ DC
Sbjct: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDC 523
Score = 38.1 bits (87), Expect = 0.068
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 878 GTSIEDILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
G S ED S CP C G GQC++ C C +S DC
Sbjct: 548 GYSGEDC-STRSCPGGCRGRGQCLDGRCVCEDGYSGEDC 585
Score = 36.6 bits (83), Expect = 0.20
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDCS 917
CP C G G+C++ C C FS DCS
Sbjct: 218 CPGDCQGRGRCVQGVCVCRAGFSGPDCS 245
Score = 35.4 bits (80), Expect = 0.44
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 887 VLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
V CP CS G+C + C C P ++ DC
Sbjct: 308 VRSCPRGCSQRGRCKDGRCVCDPGYTGEDC 337
Score = 34.7 bits (78), Expect = 0.76
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 878 GTSIEDILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
G S ED V CP C G G+C C C P ++ DC
Sbjct: 455 GYSGEDC-GVRSCPGDCRGRGRCESGRCMCWPGYTGRDC 492
Score = 34.7 bits (78), Expect = 0.76
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 889 KCPNLCSGNGQCMEWGCACSPSFSSYDCS 917
+CP C G+G C + C C +S DCS
Sbjct: 527 RCPGDCRGHGLCEDGVCVCDAGYSGEDCS 555
Score = 34.7 bits (78), Expect = 0.76
Identities = 10/33 (30%), Positives = 17/33 (51%)
Query: 886 SVLKCPNLCSGNGQCMEWGCACSPSFSSYDCSD 918
++ CP C G G+C + C C ++ DC +
Sbjct: 715 AIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGE 747
Score = 34.3 bits (77), Expect = 0.99
Identities = 12/34 (35%), Positives = 17/34 (50%)
Query: 883 DILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
D + CP CS G+C C C+P ++ DC
Sbjct: 273 DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDC 306
Score = 33.9 bits (76), Expect = 1.3
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 8/53 (15%)
Query: 865 RIVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDCS 917
R V + Y E+ GT CP C G+C++ C C P ++ DCS
Sbjct: 325 RCVCDPGYTGEDCGTR--------SCPWDCGEGGRCVDGRCVCWPGYTGEDCS 369
Score = 33.5 bits (75), Expect = 1.7
Identities = 12/34 (35%), Positives = 17/34 (50%)
Query: 883 DILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
D V CP C+ G+C + C C P ++ DC
Sbjct: 397 DDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC 430
Score = 33.1 bits (74), Expect = 2.2
Identities = 12/31 (38%), Positives = 15/31 (48%)
Query: 886 SVLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
S CP C G G+C + C C +S DC
Sbjct: 369 STRTCPRDCRGRGRCEDGECICDTGYSGDDC 399
Score = 32.7 bits (73), Expect = 2.9
Identities = 11/27 (40%), Positives = 14/27 (51%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC 916
CP C G G+C C C+ +S DC
Sbjct: 435 CPRDCRGRGRCENGVCVCNAGYSGEDC 461
Score = 32.3 bits (72), Expect = 3.7
Identities = 11/27 (40%), Positives = 14/27 (51%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC 916
CP CS G+C C C P ++ DC
Sbjct: 249 CPRGCSQRGRCEGGRCVCDPGYTGDDC 275
Score = 31.2 bits (69), Expect = 8.4
Identities = 16/52 (30%), Positives = 20/52 (38%), Gaps = 6/52 (11%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDCSDSYDKAPEI------TELGNAGFC 935
CP C G G+C++ C C + DC A EL AG C
Sbjct: 652 CPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQC 703
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 167 bits (424), Expect = 6e-41
Identities = 140/489 (28%), Positives = 190/489 (38%), Gaps = 105/489 (21%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
CLNGG+C + G Y C C G+ G CE+ C S+PC GS + C
Sbjct: 306 CLNGGTCSNT-----GPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFT--ICK 1299
+C P +T T D S N Q K +T C+
Sbjct: 361 ECSP----------GWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410
Query: 1300 Y--------PCGKSREC---VAPNICKCKPGYIGSNCQTAL--CDPDCKNHGKC---IKP 1343
PC ++ C +A C C PG++G NC + C C+N C +
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 1344 NICQCLPGHGGATCD---EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCETMV--CN 1395
C C PG+ G C+ +E + PC +GG C + C CP GF G C+ + C
Sbjct: 471 YRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCE 530
Query: 1396 RH-CENGGQC---LTPDICQCKPGWYGPTCS-------TALCD----------------- 1427
+ C+NG QC + C+C + G CS T C+
Sbjct: 531 PNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEG 590
Query: 1428 ------PVCLNGGSCNKPN----TCLCPNGFFGEHCQ---NAFCHPPCKNGGHC---MRN 1471
VC G C + TC C GF G +C N PC+NGG C + +
Sbjct: 591 VRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNS 650
Query: 1472 NVCVCREGYTGRRFQKSICDPT---CMNGGKC---VGPSTCSCPSGWSGKRCNT--PICL 1523
C+C +G+ G + +I D + C NGG C V C C +GW GK C++ C
Sbjct: 651 YKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCD 710
Query: 1524 Q-KCKNGGECIAPS---ICHCPSSWEGVRCQI---PICNPK-CLYGGRCIFPN---VCSC 1572
+ C NGG C C CP WEG C I C P C GG C+ C C
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC 770
Query: 1573 RTEYSGVKC 1581
+ + G C
Sbjct: 771 KEGWEGPIC 779
Score = 167 bits (424), Expect = 6e-41
Identities = 141/439 (32%), Positives = 180/439 (41%), Gaps = 87/439 (19%)
Query: 1181 CDCLNG--------------GSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNP 1226
CDCL G G C +D + Y C+C PG+ G CE DI C SNP
Sbjct: 436 CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNP 495
Query: 1227 CGLGSYISG-FHSYSCDCPP-------ELKVETQFVNQFTTQTVVLTRSDKSVNKEEDD- 1277
C G + + + C CP +L ++ N R+ K +D
Sbjct: 496 CLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 1278 --KNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKP---GYIGSNCQTALCDP 1332
KN K H + T PC C P YI SN +C P
Sbjct: 556 EGKNCSHLKDHCRTT----------PCEVIDSCTVAMASNDTPEGVRYISSN----VCGP 601
Query: 1333 DCKNHGKCIKPN----ICQCLPGHGGATCDE--EHC-NPPCQHGGTCLAG---NLCTCPY 1382
HGKC + C C G G C E C + PC++GGTC+ G C C
Sbjct: 602 ----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSD 657
Query: 1383 GFVGPRCETMV--CNRH-CENGGQC--LTPDI-CQCKPGWYGPTCST--ALCD-PVCLNG 1433
G+ G CET + C+++ C NGG C L D C CK GW G TC + + CD C NG
Sbjct: 658 GWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNG 717
Query: 1434 GSCNKPN---TCLCPNGFFGEHC---QNAFCHP-PCKNGGHCMRNN---VCVCREGYTGR 1483
G+C C+CP G+ G C +N+ C P PC NGG C+ N CVC+EG+ G
Sbjct: 718 GTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGP 777
Query: 1484 RFQKSI--CDP-TCMNGGKCVGPST---CSCPSGWSGKRCNTPI--CLQK-CKNGGEC-- 1532
++ C P C N G CV C C G++G C I C C G C
Sbjct: 778 ICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVD 837
Query: 1533 -IAPSICHCPSSWEGVRCQ 1550
I C CP G +CQ
Sbjct: 838 EINGYRCVCPPGHSGAKCQ 856
Score = 162 bits (409), Expect = 3e-39
Identities = 110/329 (33%), Positives = 144/329 (43%), Gaps = 45/329 (13%)
Query: 1297 ICKYPCG-KSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGA 1355
IC+ C K C P C+C+ G+ G C + P C HG C +P C C GG
Sbjct: 233 ICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQ 291
Query: 1356 TCDEE--HC--NPPCQHGGTCLAGN----LCTCPYGFVGPRCETM---VCNRHCENGGQC 1404
CD++ +C + PC +GGTC C+CP G+ GP CE + C N G C
Sbjct: 292 LCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSC 351
Query: 1405 LTPDI---CQCKPGWYGPTCSTAL--CDP-VCLNGGSCN---KPNTCLCPNGFFGEHCQ- 1454
+ C+C PGW GPTCST + C P C +GG+C C+CP + G+ CQ
Sbjct: 352 KETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1455 --NAFCHPPCKNGGHC---MRNNVCVCREGYTGRRFQKSI--CDPTCMNGGKC---VGPS 1504
N PC N C + + C C G+ G+ +I C C N C V
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGY 471
Query: 1505 TCSCPSGWSGKRCNTPI---CLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI--CNP 1556
C CP G++G C I C NGG C I C CP+ + G CQ+ I C P
Sbjct: 472 RCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEP 531
Query: 1557 K-CLYGGRC---IFPNVCSCRTEYSGVKC 1581
C G +C C C +Y G C
Sbjct: 532 NPCQNGAQCYNRASDYFCKCPEDYEGKNC 560
Score = 127 bits (318), Expect = 1e-28
Identities = 85/268 (31%), Positives = 112/268 (41%), Gaps = 40/268 (14%)
Query: 1356 TCDEEH----CNPPCQHGGTCLAGNLC------TCPYGFVGPRCETMVCNRHCE-NGGQC 1404
TCD+ + CN C+ C TC G++GP C +C + C G C
Sbjct: 186 TCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSC 245
Query: 1405 LTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQN--AFC--HP 1460
P C+C+ GW G C + P C++ G CN+P CLC + G+ C +C H
Sbjct: 246 KLPGDCRCQYGWQGLYCDKCIPHPGCVH-GICNEPWQCLCETNWGGQLCDKDLNYCGTHQ 304
Query: 1461 PCKNGGHCMRNN----VCVCREGYTGRRFQ----KSICDPTCMNGGKCVGPS---TCSCP 1509
PC NGG C C C EGY+G + + DP C N G C S C C
Sbjct: 305 PCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDP-CHNRGSCKETSLGFECECS 363
Query: 1510 SGWSGKRCNTPI---CLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI--CNPK-CLY 1560
GW+G C+T I C +GG C + C CP W G CQ+ C K C+
Sbjct: 364 PGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVN 423
Query: 1561 GGRC---IFPNVCSCRTEYSGVKCEKKI 1585
C I C C + G C+ I
Sbjct: 424 AKSCKNLIASYYCDCLPGWMGQNCDINI 451
Score = 99.0 bits (245), Expect = 3e-20
Identities = 91/329 (27%), Positives = 125/329 (37%), Gaps = 76/329 (23%)
Query: 1179 KSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGF-H 1237
+S C NGG+C+ G Y C+C G+ G+ CE +I+ C NPC G +
Sbjct: 634 ESNPCRNGGTCID------GVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVN 687
Query: 1238 SYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTI 1297
+ CDC K +T + +Q T ++ +E G+AF
Sbjct: 688 DFYCDCKNGWKGKT--CHSRDSQCDEATCNNGGTCYDE----------------GDAFK- 728
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTA---LCDPD-CKNHGKCI---KPNICQCLP 1350
C C G+ G+ C A C P+ C N G C+ + C C
Sbjct: 729 ----------------CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKE 772
Query: 1351 GHGGATC--DEEHCNP-PCQHGGTCLAGN---LCTCPYGFVGPRCETMV--C-NRHCENG 1401
G G C + C+P PC + GTC+ G+ C C GF GP C + C + C G
Sbjct: 773 GWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG 832
Query: 1402 GQC---LTPDICQCKPGWYGPTCSTALCDPVCLNGGSC--------NKPNTCLCPNGFFG 1450
C + C C PG G C P C+ GS + NTC C NG
Sbjct: 833 ATCVDEINGYRCVCPPGHSGAKCQEVSGRP-CITMGSVIPDGAKWDDDCNTCQCLNGRIA 891
Query: 1451 EHCQNAFCHP-PC---KNGGHCMRNNVCV 1475
C +C P PC K C C+
Sbjct: 892 --CSKVWCGPRPCLLHKGHSECPSGQSCI 918
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 164 bits (414), Expect = 8e-40
Identities = 112/323 (34%), Positives = 140/323 (43%), Gaps = 47/323 (14%)
Query: 1300 YPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDC-KNHGKCIKPNICQCLPGHGGATCD 1358
+ CG+ E V C PG+ G C +C P C + HG C KP C+C G G CD
Sbjct: 202 FTCGERGEKV------CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCD 255
Query: 1359 EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRC--ETMVCNRH--CENGGQCLTPD----IC 1410
E P C H GTC C C G+ G C + C H C+NG C C
Sbjct: 256 ECIRYPGCLH-GTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTC 314
Query: 1411 QCKPGWYGPTCSTAL--CDP-VCLNGGSC---NKPNTCLCPNGFFGEHCQ---NAFCHPP 1461
C+PG+ G TC + CDP C NGGSC +C CP GF+G+ C+ P
Sbjct: 315 SCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP 374
Query: 1462 CKNGGHCMRN----NVCVCREGYTGRRFQKSI--CDPT-CMNGGKCV---GPSTCSCPSG 1511
C NGG C + C C GY+G +K I C + C NG KCV C C +G
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAG 434
Query: 1512 WSGKRC--NTPICLQK-CKNGGEC---IAPSICHCPSSWEGVRCQIPIC---NPKCLYGG 1562
+SG+ C N C C NGG C + C CP + G C P+ + C G
Sbjct: 435 FSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGA 494
Query: 1563 RCI---FPNVCSCRTEYSGVKCE 1582
C VC C Y G C+
Sbjct: 495 TCHERGHRYVCECARGYGGPNCQ 517
Score = 120 bits (300), Expect = 1e-26
Identities = 87/258 (33%), Positives = 109/258 (42%), Gaps = 39/258 (15%)
Query: 1299 KYPCGKSRECVAPNICKCKPGYIGSNCQTAL--C--DPDCKNHGKCIKPN----ICQCLP 1350
+YP C P C C+ G+ G C L C CKN C C C P
Sbjct: 259 RYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP 318
Query: 1351 GHGGATCD--EEHCNP-PCQHGGTCL---AGNLCTCPYGFVGPRCE--TMVC-NRHCENG 1401
G+ GATC+ + C+P PC++GG+C CTCP GF G CE M C + C NG
Sbjct: 319 GYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNG 378
Query: 1402 GQCL-TPD---ICQCKPGWYGPTCSTAL---CDPVCLNGGSC---NKPNTCLCPNGFFGE 1451
G+C +PD C+C G+ G C + C NG C C C GF G
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGR 438
Query: 1452 HCQNAF---CHPPCKNGGHC---MRNNVCVCREGYTGRRFQKSI--CD-PTCMNGGKCVG 1502
HC + PC NGG C + + C C GYTGR + C+ C NG C
Sbjct: 439 HCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHE 498
Query: 1503 PS---TCSCPSGWSGKRC 1517
C C G+ G C
Sbjct: 499 RGHRYVCECARGYGGPNC 516
Score = 109 bits (273), Expect = 2e-23
Identities = 76/266 (28%), Positives = 103/266 (38%), Gaps = 66/266 (24%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGF-HSYSC 1241
C NG +C + G G Y C C PG+ G+ CE+ I C +PC G + +SYSC
Sbjct: 298 CKNGATCTNT-----GQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSC 352
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
CPP + K +A T P
Sbjct: 353 TCPPGF--------------------------------------YGKICELSAMTCADGP 374
Query: 1302 CGKSRECV-APN---ICKCKPGYIGSNCQTAL---CDPDCKNHGKCIKPN---ICQCLPG 1351
C C +P+ C+C GY G NC+ + C N KC+ +C+C G
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAG 434
Query: 1352 HGGATCDE---EHCNPPCQHGGTCLAGN---LCTCPYGFVGPRCETMVC---NRHCENGG 1402
G CD+ + + PC +GGTC G CTCP G+ G C V + C NG
Sbjct: 435 FSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGA 494
Query: 1403 QCLTPD---ICQCKPGWYGPTCSTAL 1425
C +C+C G+ GP C L
Sbjct: 495 TCHERGHRYVCECARGYGGPNCQFLL 520
Score = 108 bits (271), Expect = 3e-23
Identities = 70/196 (35%), Positives = 89/196 (45%), Gaps = 23/196 (11%)
Query: 1412 CKPGWYGPTCSTALCDPVC-LNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR 1470
C PGW GP C+ +C P C G C+KP C C G+ G +C +P C +G C +
Sbjct: 212 CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGT-CQQ 270
Query: 1471 NNVCVCREGYTGRRFQKSICDPT----CMNGGKCV----GPSTCSCPSGWSGKRCNTPI- 1521
C C+EG+ G + + T C NG C G TCSC G++G C I
Sbjct: 271 PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID 330
Query: 1522 -C-LQKCKNGGECIAPS---ICHCPSSWEGVRCQIPI---CNPKCLYGGRCI-FPN---V 1569
C CKNGG C C CP + G C++ + C GGRC P+
Sbjct: 331 ECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYS 390
Query: 1570 CSCRTEYSGVKCEKKI 1585
C C YSG CEKKI
Sbjct: 391 CRCPVGYSGFNCEKKI 406
Score = 86.7 bits (213), Expect = 2e-16
Identities = 66/244 (27%), Positives = 92/244 (37%), Gaps = 64/244 (26%)
Query: 1170 TRVTIEVTVKSCD---CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNP 1226
T T E+ + CD C NGGSC N Y C C PGF+G +CE+ C P
Sbjct: 321 TGATCELGIDECDPSPCKNGGSCTDLENS------YSCTCPPGFYGKICELSAMTCADGP 374
Query: 1227 CGLGSYISGF--HSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRK 1284
C G S YSC CP + S + K+ D ++
Sbjct: 375 CFNGGRCSDSPDGGYSCRCP-------------------VGYSGFNCEKKIDYCSSS--- 412
Query: 1285 RHVKPTSGNAFTICKYPCGKSRECV---APNICKCKPGYIGSNCQTALCD---PDCKNHG 1338
PC +CV +C+C+ G+ G +C + D C N G
Sbjct: 413 ----------------PCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGG 456
Query: 1339 KC---IKPNICQCLPGHGGATCDE--EHC-NPPCQHGGTCLAGN---LCTCPYGFVGPRC 1389
C + C C PG+ G C C + PC +G TC +C C G+ GP C
Sbjct: 457 TCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNC 516
Query: 1390 ETMV 1393
+ ++
Sbjct: 517 QFLL 520
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 160 bits (405), Expect = 9e-39
Identities = 102/305 (33%), Positives = 139/305 (45%), Gaps = 46/305 (15%)
Query: 1297 ICKYPCGKSRE-CVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGA 1355
IC C + C P C C+PG+ G C + C+ HG C P C C G GG
Sbjct: 221 ICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCR-HGTCSTPWQCTCDEGWGGL 279
Query: 1356 TCDEE--HC--NPPCQHGGTCLAGN----LCTCPYGFVGPRCETMV--CNRH-CENGGQC 1404
CD++ +C + PC++G TC CTC G+ G CE + C+ + C NGG C
Sbjct: 280 FCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSC 339
Query: 1405 LTPDI---CQCKPGWYGPTC--STALC-DPVCLNGGSCNKPN-----TCLCPNGFFGEHC 1453
+ C C PG+YG C ST C D C NGGSC + N C CP F G +C
Sbjct: 340 KDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNC 399
Query: 1454 QNAF---CHPPCKNGGHCMR---NNVCVCREGYTGRRFQKSICDPT---CMNGGKCVGPS 1504
+ PC NGG C+ + +C CR G+TG + + D C +GG C
Sbjct: 400 EKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLE 459
Query: 1505 T---CSCPSGWSGKRCNTPICLQKCK-----NGGECIAPS-----ICHCPSSWEGVRCQI 1551
C+CP+G+SG+RC + C N C +C+CP + G RC+
Sbjct: 460 NGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEF 519
Query: 1552 PICNP 1556
P+ P
Sbjct: 520 PVGLP 524
Score = 159 bits (402), Expect = 2e-38
Identities = 109/336 (32%), Positives = 148/336 (44%), Gaps = 52/336 (15%)
Query: 1298 CKYPCGKSRECVAPNICK------CKPGYIGSNCQTALCDPDC-KNHGKCIKPNICQCLP 1350
C C K + +C+ C PG+ G CQ +C C + +G C KP C C P
Sbjct: 184 CSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRP 243
Query: 1351 GHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMV--CNRH--CENGGQCLT 1406
G G C+E + C+H GTC CTC G+ G C+ + C H C+NG C
Sbjct: 244 GWQGRLCNECIPHNGCRH-GTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSN 302
Query: 1407 PD----ICQCKPGWYGPTCSTAL--CDP-VCLNGGSCNKPNT---CLCPNGFFGEHCQN- 1455
C C+PG+ G C L CD C NGGSC CLCP G++G HC++
Sbjct: 303 SGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHS 362
Query: 1456 --AFCHPPCKNGGHCMRNN-----VCVCREGYTGRRFQKSICDPT---CMNGGKCV--GP 1503
+ PC NGG C N C C +TG +K + T C NGG+C+ GP
Sbjct: 363 TLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGP 422
Query: 1504 S-TCSCPSGWSGKRCNTPI--CLQK-CKNGGECIAPS---ICHCPSSWEGVRCQI----- 1551
S C C G++G C + C + C +GG C +C CP+ + G RC++
Sbjct: 423 SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSID 482
Query: 1552 -----PICNPKCLYGGRCIFPNVCSCRTEYSGVKCE 1582
P N Y VC+C + G +CE
Sbjct: 483 ACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 133 bits (334), Expect = 2e-30
Identities = 96/310 (30%), Positives = 127/310 (40%), Gaps = 41/310 (13%)
Query: 1316 CKPGYIGSNCQTALCDP--DCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPC-QHGGTC 1372
C Y G NC + LC D H C CLPG G C + C C + G C
Sbjct: 175 CSDNYYGDNC-SRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYC 233
Query: 1373 LAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTAL--CD--P 1428
C C G+ G C + + C +G C TP C C GW G C L C
Sbjct: 234 SKPAECLCRPGWQGRLCNECIPHNGCRHG-TCSTPWQCTCDEGWGGLFCDQDLNYCTHHS 292
Query: 1429 VCLNGGSCNKPN----TCLCPNGFFGEHCQNAFCH---PPCKNGGHCMRNNV---CVCRE 1478
C NG +C+ TC C G+ G C+ PC+NGG C C+C
Sbjct: 293 PCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 352
Query: 1479 GYTGRRFQKSI---CDPTCMNGGKCVGPS-----TCSCPSGWSGKRCNTPI--CLQK-CK 1527
GY G + S D C NGG C + C CP ++G C + C C
Sbjct: 353 GYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCA 412
Query: 1528 NGGECI--APS-ICHCPSSWEGVRCQIPIC----NPKCLYGGRCIFPN---VCSCRTEYS 1577
NGG+C+ PS +C C + G C++ + NP C +GG C +C+C +S
Sbjct: 413 NGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNP-CAHGGTCHDLENGLMCTCPAGFS 471
Query: 1578 GVKCEKKIQI 1587
G +CE + I
Sbjct: 472 GRRCEVRTSI 481
Score = 107 bits (268), Expect = 7e-23
Identities = 82/292 (28%), Positives = 108/292 (36%), Gaps = 73/292 (25%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C NG +C + G Y C C PG+ G CE+++S C SNPC GS Y C
Sbjct: 294 CKNGATCSNS-----GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHC 348
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
CPP + + + N + QG
Sbjct: 349 LCPP------GYYGLHCEHSTLSCADSPCFNGGSCRERNQG------------------- 383
Query: 1302 CGKSRECVAPNICKCKPGYIGSNCQTAL--CDPD-CKNHGKCIK---PNICQCLPGHGGA 1355
A C+C P + GSNC+ + C + C N G+C+ +C+C PG G
Sbjct: 384 --------ANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGT 435
Query: 1356 TCD---EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDI 1409
C+ + PC HGGTC G +CTCP GF G RCE + D
Sbjct: 436 YCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT------------SIDA 483
Query: 1410 CQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPP 1461
C P + TC T L + C CP GF G C+ PP
Sbjct: 484 CASSPCFNRATCYTDLSTDTFV----------CNCPYGFVGSRCEFPVGLPP 525
Score = 79.0 bits (193), Expect = 3e-14
Identities = 47/154 (30%), Positives = 68/154 (44%), Gaps = 13/154 (8%)
Query: 1443 LCPNGFFGEHCQNAFCHPPCKNGGH--CMRNNVCVCREGYTGRRFQKSICDPTCMN-GGK 1499
+C + ++G++C C + GH C + C G+TG Q+ IC C G
Sbjct: 174 ICSDNYYGDNCSR-LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGY 232
Query: 1500 CVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQ--IPIC--N 1555
C P+ C C GW G+ CN I C++G C P C C W G+ C + C +
Sbjct: 233 CSKPAECLCRPGWQGRLCNECIPHNGCRHG-TCSTPWQCTCDEGWGGLFCDQDLNYCTHH 291
Query: 1556 PKCLYGGRCIFPN----VCSCRTEYSGVKCEKKI 1585
C G C C+CR Y+GV CE ++
Sbjct: 292 SPCKNGATCSNSGQRSYTCTCRPGYTGVDCELEL 325
Score = 63.5 bits (153), Expect = 2e-09
Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 1475 VCREGYTGRRFQKSICDPTCMNGGKCVGPSTC------SCPSGWSGKRCNTPICLQKC-K 1527
+C + Y G C C G C SC GW+G+ C PICL C +
Sbjct: 174 ICSDNYYGDN-----CSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHE 228
Query: 1528 NGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKIQI 1587
G C P+ C C W+G C I + C +G C P C+C + G+ C++ +
Sbjct: 229 QNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHG-TCSTPWQCTCDEGWGGLFCDQDLNY 287
Query: 1588 RRH 1590
H
Sbjct: 288 CTH 290
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 156 bits (395), Expect = 1e-37
Identities = 87/265 (32%), Positives = 118/265 (44%), Gaps = 18/265 (6%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357
C C + ECV+ +C C PG++G++C A C C +G+ K CQC G GA C
Sbjct: 576 CPRNCHGNGECVS-GVCHCFPGFLGADCAKAACPVLCSGNGQYSK-GTCQCYSGWKGAEC 633
Query: 1358 D---EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVC-NRHCENGGQCLTPDICQCK 1413
D + +P C G+C+ GN C C G+ G CE + C + C + G C+ + C C
Sbjct: 634 DVPMNQCIDPSCGGHGSCIDGN-CVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGE-CLCS 691
Query: 1414 PGWYGPTCSTA--LCDPVCLNGGSCNKPNT--CLCPNGFFGEHCQNAFCHPPCKNGGHCM 1469
PGW G C A C C +G P+T C C + G C C C G C+
Sbjct: 692 PGWGGLNCELARVQCPDQC-SGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCI 750
Query: 1470 RNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNG 1529
C C EG+TG + +C P C+ G C C C GW+G+ C C C
Sbjct: 751 -GGACRCEEGWTGAACDQRVCHPRCIEHGTC-KDGKCECREGWNGEHCTIDGCPDLCNGN 808
Query: 1530 GECIAPS---ICHCPSSWEGVRCQI 1551
G C C C + W G C +
Sbjct: 809 GRCTLGQNSWQCVCQTGWRGPGCNV 833
Score = 137 bits (346), Expect = 6e-32
Identities = 77/230 (33%), Positives = 102/230 (44%), Gaps = 15/230 (6%)
Query: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
+ C C G C++G +C C GF+G C C C GQ + CQC GW G
Sbjct: 574 QDCPRNCHGNGECVSG-VCHCFPGFLGADCAKAACPVLCSGNGQ-YSKGTCQCYSGWKGA 631
Query: 1420 TCSTAL---CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475
C + DP C GSC N C+C G+ GEHC+ C P C + G C+ N C+
Sbjct: 632 ECDVPMNQCIDPSCGGHGSCIDGN-CVCSAGYKGEHCEEVDCLDPTCSSHGVCV-NGECL 689
Query: 1476 CREGYTGRRFQ--KSICDPTCMNGGKCVGPST--CSCPSGWSGKRCNTPICLQKCKNGGE 1531
C G+ G + + C C G + P T CSC W G C+ +C C G
Sbjct: 690 CSPGWGGLNCELARVQCPDQCSGHGTYL-PDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 748
Query: 1532 CIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
CI C C W G C +C+P+C+ G C C CR ++G C
Sbjct: 749 CIG-GACRCEEGWTGAACDQRVCHPRCIEHGTC-KDGKCECREGWNGEHC 796
Score = 132 bits (332), Expect = 3e-30
Identities = 78/262 (29%), Positives = 106/262 (40%), Gaps = 16/262 (6%)
Query: 1330 CDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRC 1389
C +C +G+C+ +C C PG GA C + C C G G C C G+ G C
Sbjct: 576 CPRNCHGNGECVS-GVCHCFPGFLGADCAKAACPVLCSGNGQYSKGT-CQCYSGWKGAEC 633
Query: 1390 ETMV---CNRHCENGGQCLTPDICQCKPGWYGPTCSTALC-DPVCLNGGSCNKPNTCLCP 1445
+ + + C G C+ + C C G+ G C C DP C + G C CLC
Sbjct: 634 DVPMNQCIDPSCGGHGSCIDGN-CVCSAGYKGEHCEEVDCLDPTCSSHGVCVN-GECLCS 691
Query: 1446 NGFFGEHCQNAFCHPPCKNGGH---CMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVG 1502
G+ G +C+ A P + GH +C C + G +C C G C+G
Sbjct: 692 PGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG 751
Query: 1503 PSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGG 1562
C C GW+G C+ +C +C G C C C W G C I C C G
Sbjct: 752 -GACRCEEGWTGAACDQRVCHPRCIEHGTC-KDGKCECREGWNGEHCTIDGCPDLCNGNG 809
Query: 1563 RCIFPN---VCSCRTEYSGVKC 1581
RC C C+T + G C
Sbjct: 810 RCTLGQNSWQCVCQTGWRGPGC 831
Score = 104 bits (260), Expect = 6e-22
Identities = 96/356 (26%), Positives = 132/356 (37%), Gaps = 57/356 (16%)
Query: 1177 TVKSC--DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGS-----LCEVDISGCQSNPCGL 1229
+V+ C +C G CVS +C C PGF G+ C V SG G
Sbjct: 572 SVQDCPRNCHGNGECVSG----------VCHCFPGFLGADCAKAACPVLCSGNGQYSKGT 621
Query: 1230 GSYISGFHSYSCDCPPELKVETQFVNQFTT--QTVVLTRSDKSVNKEEDDKNAQGRKRHV 1287
SG+ CD P ++ + V + K + EE D H
Sbjct: 622 CQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHG 681
Query: 1288 KPTSGN--------------AFTICKYPC-GKSRECVAPNICKCKPGYIGSNCQTALCDP 1332
+G A C C G +C C P ++G +C +C
Sbjct: 682 VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSV 741
Query: 1333 DCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETM 1392
DC HG CI C+C G GA CD+ C+P C GTC G C C G+ G C
Sbjct: 742 DCGTHGVCI-GGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGK-CECREGWNGEHCTID 799
Query: 1393 VCNRHCENGGQCLTPD---ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN------TCL 1443
C C G+C C C+ GW GP C+ A+ + C + NK N CL
Sbjct: 800 GCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAM-ETSCAD----NKDNEGDGLVDCL 854
Query: 1444 CPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGK 1499
P+ CQN+ C+ R+ + + ++G T KS D + GK
Sbjct: 855 DPDCCLQSACQNSLL---CRGS----RDPLDIIQQGQTDWPAVKSFYDRIKLLAGK 903
Score = 82.0 bits (201), Expect = 4e-15
Identities = 63/249 (25%), Positives = 84/249 (33%), Gaps = 71/249 (28%)
Query: 1175 EVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYIS 1234
EV C + G CV+ C+C PG+ G CE+ C G G+Y+
Sbjct: 669 EVDCLDPTCSSHGVCVNGE----------CLCSPGWGGLNCELARVQCPDQCSGHGTYLP 718
Query: 1235 GFHSYSCD---CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTS 1291
SCD P+ VE
Sbjct: 719 DTGLCSCDPNWMGPDCSVE----------------------------------------- 737
Query: 1292 GNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPG 1351
+C CG C+ C+C+ G+ G+ C +C P C HG C K C+C G
Sbjct: 738 -----VCSVDCGTHGVCIG-GACRCEEGWTGAACDQRVCHPRCIEHGTC-KDGKCECREG 790
Query: 1352 HGGATCDEEHCNPPCQHGGTCLAGN---LCTCPYGFVGPRCETMV---CNRHCENGG--- 1402
G C + C C G C G C C G+ GP C + C + +N G
Sbjct: 791 WNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGL 850
Query: 1403 -QCLTPDIC 1410
CL PD C
Sbjct: 851 VDCLDPDCC 859
Score = 39.3 bits (90), Expect = 0.031
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 886 SVLKCPNLCSGNGQCMEWGCACSPSFSSYDCS 917
SV CP C GNG+C+ C C P F DC+
Sbjct: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCA 603
Score = 34.3 bits (77), Expect = 0.99
Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 11/73 (15%)
Query: 854 GVALLENECEKRIVE-----EGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCM----EWG 904
G A + C R +E +GK E + ++ CP+LC+GNG+C W
Sbjct: 762 GAACDQRVCHPRCIEHGTCKDGKCECREGWNG--EHCTIDGCPDLCNGNGRCTLGQNSWQ 819
Query: 905 CACSPSFSSYDCS 917
C C + C+
Sbjct: 820 CVCQTGWRGPGCN 832
Score = 32.0 bits (71), Expect = 4.9
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC 916
CP LCSGNGQ + C C + +C
Sbjct: 607 CPVLCSGNGQYSKGTCQCYSGWKGAEC 633
Score = 31.2 bits (69), Expect = 8.4
Identities = 14/35 (40%), Positives = 24/35 (68%), Gaps = 2/35 (5%)
Query: 885 LSVLKCPNLCSGNGQCM-EWG-CACSPSFSSYDCS 917
L+ ++CP+ CSG+G + + G C+C P++ DCS
Sbjct: 701 LARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCS 735
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 153 bits (387), Expect = 1e-36
Identities = 84/264 (31%), Positives = 111/264 (42%), Gaps = 16/264 (6%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357
C C + ECV+ C C PG++G +C A C C +G+ K C C G G C
Sbjct: 518 CPRNCHGNGECVS-GTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGR-CLCFSGWKGTEC 575
Query: 1358 D---EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVC-NRHCENGGQCLTPDICQCK 1413
D + +P C G C+ G+ C C G+ G CE C + C N G C+ + C C
Sbjct: 576 DVPTTQCIDPQCGGRGICIMGS-CACNSGYKGESCEEADCIDPGCSNHGVCIHGE-CHCS 633
Query: 1414 PGWYGPTCS--TALCDPVCLNGGS-CNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR 1470
PGW G C +C C G+ + +C C + G C N C C + G CM
Sbjct: 634 PGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCM- 692
Query: 1471 NNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGG 1530
C C EG+TG + C P C G C C C GW+G+ C C C + G
Sbjct: 693 GGTCRCEEGWTGPACNQRACHPRCAEHGTC-KDGKCECSQGWNGEHCTIEGCPGLCNSNG 751
Query: 1531 ECIAPS---ICHCPSSWEGVRCQI 1551
C C C W G C +
Sbjct: 752 RCTLDQNGWHCVCQPGWRGAGCDV 775
Score = 139 bits (349), Expect = 3e-32
Identities = 81/263 (30%), Positives = 105/263 (39%), Gaps = 16/263 (6%)
Query: 1330 CDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRC 1389
C +C +G+C+ C C PG G C C C G G C C G+ G C
Sbjct: 518 CPRNCHGNGECVS-GTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGR-CLCFSGWKGTEC 575
Query: 1390 E---TMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALC-DPVCLNGGSCNKPNTCLCP 1445
+ T + C G C+ C C G+ G +C A C DP C N G C C C
Sbjct: 576 DVPTTQCIDPQCGGRGICIMGS-CACNSGYKGESCEEADCIDPGCSNHGVCIH-GECHCS 633
Query: 1446 NGFFGEHCQ--NAFCHPPCK-NGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVG 1502
G+ G +C+ C C +G + + C C +TG IC C + G C+G
Sbjct: 634 PGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG 693
Query: 1503 PSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGG 1562
TC C GW+G CN C +C G C C C W G C I C C G
Sbjct: 694 -GTCRCEEGWTGPACNQRACHPRCAEHGTC-KDGKCECSQGWNGEHCTIEGCPGLCNSNG 751
Query: 1563 RCIFPN---VCSCRTEYSGVKCE 1582
RC C C+ + G C+
Sbjct: 752 RCTLDQNGWHCVCQPGWRGAGCD 774
Score = 137 bits (346), Expect = 6e-32
Identities = 105/368 (28%), Positives = 139/368 (37%), Gaps = 87/368 (23%)
Query: 1163 NDDCDAE----TRVTIEVTVKSC-DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHG----- 1212
ND +AE + IE V+ +C G CVS C C PGF G
Sbjct: 497 NDGKNAEQVSFNTIVIESVVECPRNCHGNGECVSGT----------CHCFPGFLGPDCSR 546
Query: 1213 SLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVN 1272
+ C V SG G SG+ CD P ++ Q
Sbjct: 547 AACPVLCSGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQ-------------------- 586
Query: 1273 KEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALC-D 1331
CG C+ + C C GY G +C+ A C D
Sbjct: 587 -----------------------------CGGRGICIMGS-CACNSGYKGESCEEADCID 616
Query: 1332 PDCKNHGKCIKPNICQCLPGHGGATCD--EEHCNPPCQHGGTCL-AGNLCTCPYGFVGPR 1388
P C NHG CI C C PG GG+ C+ + C C GT L CTC + GP
Sbjct: 617 PGCSNHGVCIHGE-CHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPD 675
Query: 1389 CETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGF 1448
C +C+ C + G C+ C+C+ GW GP C+ C P C G+C K C C G+
Sbjct: 676 CSNEICSVDCGSHGVCM-GGTCRCEEGWTGPACNQRACHPRCAEHGTC-KDGKCECSQGW 733
Query: 1449 FGEHCQNAFCHPPCKNGGHCMRNN---VCVCREGYTGRR---FQKSICDPTCMNGG---- 1498
GEHC C C + G C + CVC+ G+ G +++C + N G
Sbjct: 734 NGEHCTIEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLI 793
Query: 1499 KCVGPSTC 1506
C+ P C
Sbjct: 794 DCMDPDCC 801
Score = 61.6 bits (148), Expect = 6e-09
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 1490 CDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRC 1549
C C G+CV TC C G+ G C+ C C G+ + C C S W+G C
Sbjct: 518 CPRNCHGNGECVS-GTCHCFPGFLGPDCSRAACPVLCSGNGQ-YSKGRCLCFSGWKGTEC 575
Query: 1550 QIPIC---NPKCLYGGRCIFPNVCSCRTEYSGVKCEK 1583
+P +P+C G CI + C+C + Y G CE+
Sbjct: 576 DVPTTQCIDPQCGGRGICIMGS-CACNSGYKGESCEE 611
Score = 47.8 bits (112), Expect = 9e-05
Identities = 33/104 (31%), Positives = 45/104 (43%), Gaps = 13/104 (12%)
Query: 869 EGKYNTEEYGTSIEDILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDCS----------- 917
+GK N E+ + I SV++CP C GNG+C+ C C P F DCS
Sbjct: 498 DGK-NAEQVSFNTIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGN 556
Query: 918 DSYDKAPEITELGNAGF-CDVQKYNCMMVRVFGKGFKELPSIKC 960
Y K + G G CDV C+ + G+G + S C
Sbjct: 557 GQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICIMGSCAC 600
Score = 33.9 bits (76), Expect = 1.3
Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 877 YGTSIEDILSVLKCPNLCSGNGQCME--WGCACSPSFSSYDCSDSYDKAPEITELGNAGF 934
+G S +IL + CP+ CSG+G ++ C C P+++ DCS+ + G+ G
Sbjct: 636 WGGSNCEILKTM-CPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICS----VDCGSHGV 690
Query: 935 C 935
C
Sbjct: 691 C 691
Score = 33.1 bits (74), Expect = 2.2
Identities = 12/31 (38%), Positives = 15/31 (48%), Gaps = 4/31 (12%)
Query: 890 CPNLCSGNGQCM----EWGCACSPSFSSYDC 916
CP LC+ NG+C W C C P + C
Sbjct: 743 CPGLCNSNGRCTLDQNGWHCVCQPGWRGAGC 773
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 152 bits (383), Expect = 3e-36
Identities = 103/329 (31%), Positives = 138/329 (41%), Gaps = 45/329 (13%)
Query: 1297 ICKYPCGKSRE-CVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGA 1355
+CK C C P C+C G+ G C + P C HG C++P C C GG
Sbjct: 244 VCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGL 302
Query: 1356 TCDEE--HC--NPPCQHGGTCLAGN----LCTCPYGFVGPRCETM--VCNRH-CENGGQC 1404
CD++ +C + PC +GGTC+ CTCP G+ G CE C + C NGG C
Sbjct: 303 LCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC 362
Query: 1405 LTPDI---CQCKPGWYGPTCSTAL---CDPVCLNGGSCNKP---NTCLCPNGFFGEHCQ- 1454
C C GW GPTC+ + C GG+C C+CP + G CQ
Sbjct: 363 HEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL 422
Query: 1455 --NAFCHPPCKNGGHC---MRNNVCVCREGYTGRRFQKSI--CDPTCMNGGKC---VGPS 1504
N PC N C + C C G+ G ++ C C +GG C V
Sbjct: 423 DANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGY 482
Query: 1505 TCSCPSGWSGKRC---NTPICLQKCKNGGEC--IAPSI-CHCPSSWEGVRCQIPI--CNP 1556
C CP G+ G+ C C +GG C +A CHCP + G C++ + C P
Sbjct: 483 QCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP 542
Query: 1557 K-CLYGGRCI---FPNVCSCRTEYSGVKC 1581
C G RC C+C ++ G C
Sbjct: 543 SPCRNGARCYNLEGDYYCACPDDFGGKNC 571
Score = 150 bits (380), Expect = 7e-36
Identities = 136/473 (28%), Positives = 178/473 (37%), Gaps = 116/473 (24%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGL-GSYISGFHSYSC 1241
C NGGSC SG + C C G+ G C +DI C SNPC G+ + + C
Sbjct: 356 CANGGSC-----HEVPSG-FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFEC 409
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
CP Q+ T L D +G KP NAF+ CK
Sbjct: 410 ICP----------EQWVGATCQL-----------DANECEG-----KPCL-NAFS-CK-- 439
Query: 1302 CGKSRECVAPNICKCKPGYIGSNCQTAL--CDPDCKNHGKC---IKPNICQCLPGHGGAT 1356
+ C C PG+ G NC + C C++ G C + C C G GG
Sbjct: 440 -----NLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRH 494
Query: 1357 CD---EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCETMV--CN-RHCENGGQCLTP 1407
C+ +E + PC GG C G C CP GF GP CE V C C NG +C
Sbjct: 495 CELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNL 554
Query: 1408 D---ICQCKPGWYGPTCST--------------------------ALCDPVCLNGGSC-N 1437
+ C C + G CS VC G C +
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVS 614
Query: 1438 KPN---TCLCPNGFFGEHCQNAF---CHPPCKNGGHCMRN---NVCVCREGYTGRRFQKS 1488
+P +C+C +GF G +C PC+NGG C+ C C G+ G +
Sbjct: 615 QPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTN 674
Query: 1489 ----ICDPTCMNGGKC---VGPSTCSCPSGWSGKRCNT---PICLQKCKNGGECIAPS-- 1536
+ DP C + G+C V C+C GW GK C++ C NGG C
Sbjct: 675 PNDCLPDP-CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDT 733
Query: 1537 -ICHCPSSWEGVRCQI---PICNPK-CLYGGRCIFPNV---CSCRTEYSGVKC 1581
C CP W+G C + C P C+ GG C+ C CR + G C
Sbjct: 734 FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTC 786
Score = 144 bits (363), Expect = 7e-34
Identities = 135/464 (29%), Positives = 183/464 (39%), Gaps = 79/464 (17%)
Query: 1172 VTIEVTVKSC--DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGL 1229
+ + V C C +GG+C N Y CVC GF G CE++ C S+PC
Sbjct: 456 INCHINVNDCRGQCQHGGTCKDLVNG------YQCVCPRGFGGRHCELERDECASSPCHS 509
Query: 1230 GSYIS----GFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKE-------EDDK 1278
G GFH C CP V+ + + N E DD
Sbjct: 510 GGLCEDLADGFH---CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 566
Query: 1279 NAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHG 1338
+ +P G A + CG PG G+ + +C P HG
Sbjct: 567 GGKNCSVPREPCPGGACRVID-GCGSD----------AGPGMPGT-AASGVCGP----HG 610
Query: 1339 KCIKPN----ICQCLPGHGGATCDE--EHC-NPPCQHGGTCLA---GNLCTCPYGFVGPR 1388
+C+ C C G G C E + C PC++GGTC+ C CP G+ G
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670
Query: 1389 CETMVCN---RHCENGGQC--LTPDI-CQCKPGWYGPTCSTA--LCDP-VCLNGGSCNKP 1439
C+T + C + G+C L D C C GW G TC + CD C NGG+C
Sbjct: 671 CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS 730
Query: 1440 NT---CLCPNGFFGEHC---QNAFCHP-PCKNGGHCMRNNV---CVCREGYTGRRFQKSI 1489
C CP G+ G C +N+ C P PC NGG C+ + C+CR+G+ GR +
Sbjct: 731 GDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNT 790
Query: 1490 --CDPT-CMNGGKCVGPST---CSCPSGWSGKRCNTPI--CLQK-CKNGGECIAPSI--- 1537
C+P C NGG CV C C G++G C I C C G C+
Sbjct: 791 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 850
Query: 1538 CHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
C CP G RCQ I + + FP+ S + + +C
Sbjct: 851 CSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC 894
Score = 137 bits (345), Expect = 8e-32
Identities = 135/458 (29%), Positives = 176/458 (38%), Gaps = 72/458 (15%)
Query: 1181 CD-CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQS-NPCGLGSYISGFH- 1237
CD C+ CV P + C C + G LC+ D++ C S +PC G
Sbjct: 273 CDECVPYPGCVHGSCVEP----WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 328
Query: 1238 -SYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVK-----PTS 1291
Y C CP + + + S+ N + G + H PT
Sbjct: 329 DQYRCTCP------DGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382
Query: 1292 GNAFTIC-KYPCGKSRECVAP---NICKCKPGYIGSNCQTAL--CD-PDCKNHGKC---I 1341
C PC CV C C ++G+ CQ C+ C N C I
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLI 442
Query: 1342 KPNICQCLPGHGGATC--DEEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCE---TMV 1393
C C+PG G C + C CQHGGTC + G C CP GF G CE
Sbjct: 443 GGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDEC 502
Query: 1394 CNRHCENGGQCLTPDI-----CQCKPGWYGPTC--STALCDP-VCLNGGSC---NKPNTC 1442
+ C +GG C D+ C C G+ GP C LC+P C NG C C
Sbjct: 503 ASSPCHSGGLC--EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYC 560
Query: 1443 LCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCV- 1501
CP+ F G++C + PC GG C + C G + C G+CV
Sbjct: 561 ACPDDFGGKNC--SVPREPCP-GGACRVIDGC---GSDAGPGMPGTAASGVCGPHGRCVS 614
Query: 1502 ---GPSTCSCPSGWSGKRCNTPI--CL-QKCKNGGECI---APSICHCPSSWEGVRCQI- 1551
G +C C SG++G C+ I CL Q C+NGG CI C CPS WEG C
Sbjct: 615 QPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTN 674
Query: 1552 -PICNP-KCLYGGRC---IFPNVCSCRTEYSGVKCEKK 1584
C P C GRC + C+C + G C +
Sbjct: 675 PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Score = 90.9 bits (224), Expect = 9e-18
Identities = 98/377 (25%), Positives = 133/377 (35%), Gaps = 104/377 (27%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C NGG+C+ + + + C C G+ G LC+ + + C +PC G + + C
Sbjct: 645 CRNGGTCIDEVD------AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 698
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
C K +T +F + + SG+ F
Sbjct: 699 ACDDGWKGKTCHSREFQCDAYTCSNGGTCYD------------------SGDTFR----- 735
Query: 1302 CGKSRECVAPNICKCKPGYIGSNCQTA---LCDPD-CKNHGKCIKPNI---CQCLPGHGG 1354
C C PG+ GS C A C P+ C N G C+ C C G G
Sbjct: 736 ------------CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEG 783
Query: 1355 ATC--DEEHCNP-PCQHGGTCLAG---NLCTCPYGFVGPRCETMVCNRHCENGGQCLTPD 1408
TC + CNP PC +GG C+ G C C GF GP C + D
Sbjct: 784 RTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINI--------------D 829
Query: 1409 ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAF-----C---HP 1460
CQ P YG TC +NG C+ CP G G CQ C
Sbjct: 830 ECQSSPCAYGATCVDE------INGYRCS------CPPGRAGPRCQEVIGFGRSCWSRGT 877
Query: 1461 PCKNGGHCMRN-NVCVCREGYTGRRFQKSICD-PTCMNGGKCVGPSTCSCPSGWSGKRCN 1518
P +G + + N C C +G R K C C+ G+ S CP G
Sbjct: 878 PFPHGSSWVEDCNSCRCLDG--RRDCSKVWCGWKPCLLAGQPEALS-AQCPLGQR----- 929
Query: 1519 TPICLQKCKNGGECIAP 1535
CL+K G+C+ P
Sbjct: 930 ---CLEKAP--GQCLRP 941
Score = 78.6 bits (192), Expect = 5e-14
Identities = 64/228 (28%), Positives = 87/228 (38%), Gaps = 59/228 (25%)
Query: 1411 QCKPGWYGPTCSTALCDPVCLNGG--SCNKPNTCLCPNGFFGEHCQNAFCHPPCK--NGG 1466
+C +Y TC+ C P G +C++ C +G+ G+ C+ A C C +GG
Sbjct: 197 RCDENYYSATCNK-FCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG 255
Query: 1467 HCMRNNVCVCREGYTGRRFQKSI--------------------------CDP-------- 1492
C C C G+ GR + + CD
Sbjct: 256 -CTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 1493 -TCMNGGKCVGPS----TCSCPSGWSGKRCNTP--ICLQK-CKNGGEC-IAPS--ICHCP 1541
C NGG C+ C+CP G+SG+ C C C NGG C PS CHCP
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374
Query: 1542 SSWEGVRCQIPI----CNPKCLYGGRCIFP---NVCSCRTEYSGVKCE 1582
S W G C + I NP C GG C+ C C ++ G C+
Sbjct: 375 SGWSGPTCALDIDECASNP-CAAGGTCVDQVDGFECICPEQWVGATCQ 421
Score = 70.1 bits (170), Expect = 2e-11
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 1485 FQKSICDPTCMNGGKCVGPSTC------SCPSGWSGKRCNTPICLQKCK--NGGECIAPS 1536
+ + C+ C G TC +C GW GK C +C Q C +GG C P
Sbjct: 202 YYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG-CTVPG 260
Query: 1537 ICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKI 1585
C C W+G C + P C++G C+ P C+C T + G+ C+K +
Sbjct: 261 ECRCSYGWQGRFCDECVPYPGCVHGS-CVEPWQCNCETNWGGLLCDKDL 308
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 149 bits (376), Expect = 2e-35
Identities = 95/294 (32%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1297 ICKYPCGKSRE-CVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGA 1355
+CK C C P C+C G+ G C + P C HG C++P C C GG
Sbjct: 244 VCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGL 302
Query: 1356 TCDEE--HC--NPPCQHGGTCLAGN----LCTCPYGFVGPRCETM--VCNRH-CENGGQC 1404
CD++ +C + PC +GGTC+ CTCP G+ G CE C + C NGG C
Sbjct: 303 LCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC 362
Query: 1405 LTPDI---CQCKPGWYGPTCSTAL---CDPVCLNGGSCNKP---NTCLCPNGFFGEHCQN 1455
C C GW GPTC+ + C GG+C C+CP + G CQ
Sbjct: 363 HEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL 422
Query: 1456 AF--CHPPCKNGGHC---MRNNVCVCREGYTGR--RFQKSIC-DPTCMNGGKCVGPST-- 1505
C C++GG C + CVC G+ GR ++ C C +GG C +
Sbjct: 423 DVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGF 482
Query: 1506 -CSCPSGWSGKRCNTPICL---QKCKNGGECI---APSICHCPSSWEGVRCQIP 1552
C CP G+SG C + L C+NG C C CP + G C +P
Sbjct: 483 HCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVP 536
Score = 144 bits (364), Expect = 5e-34
Identities = 136/463 (29%), Positives = 184/463 (39%), Gaps = 79/463 (17%)
Query: 1173 TIEVTVKSC--DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLG 1230
T ++ V C C +GG+C N Y CVC GF G CE++ C S+PC G
Sbjct: 419 TCQLDVNDCRGQCQHGGTCKDLVNG------YQCVCPRGFGGRHCELERDECASSPCHSG 472
Query: 1231 SYIS----GFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKE-------EDDKN 1279
GFH C CP V+ + + N E DD
Sbjct: 473 GLCEDLADGFH---CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFG 529
Query: 1280 AQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGK 1339
+ +P G A + CG PG G+ + +C P HG+
Sbjct: 530 GKNCSVPREPCPGGACRVID-GCGSD----------AGPGMPGT-AASGVCGP----HGR 573
Query: 1340 CIKPN----ICQCLPGHGGATCDE--EHC-NPPCQHGGTCLA---GNLCTCPYGFVGPRC 1389
C+ C C G G C E + C PC++GGTC+ C CP G+ G C
Sbjct: 574 CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC 633
Query: 1390 ETMVCN---RHCENGGQC--LTPDI-CQCKPGWYGPTCSTA--LCDP-VCLNGGSCNKPN 1440
+T + C + G+C L D C C GW G TC + CD C NGG+C
Sbjct: 634 DTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSG 693
Query: 1441 T---CLCPNGFFGEHC---QNAFCHP-PCKNGGHCMRNNV---CVCREGYTGRRFQKSI- 1489
C CP G+ G C +N+ C P PC NGG C+ + C+CR+G+ GR +
Sbjct: 694 DTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTN 753
Query: 1490 -CDPT-CMNGGKCVGPST---CSCPSGWSGKRCNTPI--CLQK-CKNGGECIAPSI---C 1538
C+P C NGG CV C C G++G C I C C G C+ C
Sbjct: 754 DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRC 813
Query: 1539 HCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
CP G RCQ I + + FP+ S + + +C
Sbjct: 814 SCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC 856
Score = 144 bits (363), Expect = 7e-34
Identities = 129/476 (27%), Positives = 172/476 (36%), Gaps = 121/476 (25%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHS-YSC 1241
C NGG+C+ N P Y C C G+ G CE C SNPC G S + C
Sbjct: 317 CTNGGTCI---NAEPDQ--YRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC 371
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
CP + ++ T L + + N P
Sbjct: 372 HCP----------SGWSGPTCALDIDECASN----------------------------P 393
Query: 1302 CGKSRECVAPNI---CKCKPGYIGSNCQTAL--CDPDCKNHGKC---IKPNICQCLPGHG 1353
C CV C C ++G+ CQ + C C++ G C + C C G G
Sbjct: 394 CAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG 453
Query: 1354 GATCD---EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCETMV--CNRH-CENGGQC 1404
G C+ +E + PC GG C G C CP GF GP CE V C C NG +C
Sbjct: 454 GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARC 513
Query: 1405 LTPD---ICQCKPGWYGPTCST--------------------------ALCDPVCLNGGS 1435
+ C C + G CS VC G
Sbjct: 514 YNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 573
Query: 1436 C-NKPN---TCLCPNGFFGEHCQNAF---CHPPCKNGGHCMRNNV---CVCREGYTGRRF 1485
C ++P +C+C +GF G +C PC+NGG C+ C C G+ G
Sbjct: 574 CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC 633
Query: 1486 QKS----ICDPTCMNGGKC---VGPSTCSCPSGWSGKRCNT---PICLQKCKNGGECIAP 1535
+ + DP C + G+C V C+C GW GK C++ C NGG C
Sbjct: 634 DTNPNDCLPDP-CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS 692
Query: 1536 SI---CHCPSSWEGVRCQI---PICNPK-CLYGGRCIFPNV---CSCRTEYSGVKC 1581
C CP W+G C + C P C+ GG C+ C CR + G C
Sbjct: 693 GDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTC 748
Score = 142 bits (357), Expect = 3e-33
Identities = 97/304 (31%), Positives = 131/304 (43%), Gaps = 39/304 (12%)
Query: 1316 CKPGYIGSNCQTALCDPDCKN-HGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLA 1374
C G++G C+ A+C C HG C P C+C G G CDE P C H G+C+
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVH-GSCVE 289
Query: 1375 GNLCTCPYGFVGPRCETMV--CNRH--CENGGQCLT--PD--ICQCKPGWYGPTCST--- 1423
C C + G C+ + C H C NGG C+ PD C C G+ G C
Sbjct: 290 PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEH 349
Query: 1424 ALCDPVCLNGGSCNKPNT---CLCPNGFFGEHCQ---NAFCHPPCKNGGHC---MRNNVC 1474
A C NGGSC++ + C CP+G+ G C + PC GG C + C
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFEC 409
Query: 1475 VCREGYTGRRFQKSI--CDPTCMNGGKC---VGPSTCSCPSGWSGKRC---NTPICLQKC 1526
+C E + G Q + C C +GG C V C CP G+ G+ C C
Sbjct: 410 ICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPC 469
Query: 1527 KNGGEC--IAPSI-CHCPSSWEGVRCQIPI--CNPK-CLYGGRCI---FPNVCSCRTEYS 1577
+GG C +A CHCP + G C++ + C P C G RC C+C ++
Sbjct: 470 HSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFG 529
Query: 1578 GVKC 1581
G C
Sbjct: 530 GKNC 533
Score = 101 bits (251), Expect = 7e-21
Identities = 113/407 (27%), Positives = 150/407 (36%), Gaps = 81/407 (19%)
Query: 1161 RLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDIS 1220
R+ D C ++ + T S C G CVS PG G + C+C GF G+ C +I
Sbjct: 546 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ----PG-GNFSCICDSGFTGTYCHENID 600
Query: 1221 GCQSNPC-GLGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEED--- 1276
C PC G+ I ++ C CP + E N + + D
Sbjct: 601 DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 660
Query: 1277 --DKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPN---ICKCKPGYIGSNCQTA--- 1328
D +G+ H + +A+T C C C C PG+ GS C A
Sbjct: 661 ACDDGWKGKTCHSREFQCDAYT-----CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS 715
Query: 1329 LCDPD-CKNHGKCIKPNI---CQCLPGHGGATC--DEEHCNP-PCQHGGTCLAG---NLC 1378
C P+ C N G C+ C C G G TC + CNP PC +GG C+ G C
Sbjct: 716 SCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRC 775
Query: 1379 TCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNK 1438
C GF GP C + D CQ P YG TC +NG C+
Sbjct: 776 ECAPGFAGPDCRINI--------------DECQSSPCAYGATCVDE------INGYRCS- 814
Query: 1439 PNTCLCPNGFFGEHCQNAF-----C---HPPCKNGGHCMRN-NVCVCREGYTGRRFQKSI 1489
CP G G CQ C P +G + + N C C +G R K
Sbjct: 815 -----CPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDG--RRDCSKVW 867
Query: 1490 CD-PTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAP 1535
C C+ G+ S CP G CL+K G+C+ P
Sbjct: 868 CGWKPCLLAGQPEALS-AQCPLGQR--------CLEKAP--GQCLRP 903
Score = 78.6 bits (192), Expect = 5e-14
Identities = 64/228 (28%), Positives = 87/228 (38%), Gaps = 59/228 (25%)
Query: 1411 QCKPGWYGPTCSTALCDPVCLNGG--SCNKPNTCLCPNGFFGEHCQNAFCHPPCK--NGG 1466
+C +Y TC+ C P G +C++ C +G+ G+ C+ A C C +GG
Sbjct: 197 RCDENYYSATCNK-FCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG 255
Query: 1467 HCMRNNVCVCREGYTGRRFQKSI--------------------------CDP-------- 1492
C C C G+ GR + + CD
Sbjct: 256 -CTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 1493 -TCMNGGKCVGPS----TCSCPSGWSGKRCNTP--ICLQK-CKNGGEC-IAPS--ICHCP 1541
C NGG C+ C+CP G+SG+ C C C NGG C PS CHCP
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374
Query: 1542 SSWEGVRCQIPI----CNPKCLYGGRCIFP---NVCSCRTEYSGVKCE 1582
S W G C + I NP C GG C+ C C ++ G C+
Sbjct: 375 SGWSGPTCALDIDECASNP-CAAGGTCVDQVDGFECICPEQWVGATCQ 421
Score = 70.1 bits (170), Expect = 2e-11
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 1485 FQKSICDPTCMNGGKCVGPSTC------SCPSGWSGKRCNTPICLQKCK--NGGECIAPS 1536
+ + C+ C G TC +C GW GK C +C Q C +GG C P
Sbjct: 202 YYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG-CTVPG 260
Query: 1537 ICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKI 1585
C C W+G C + P C++G C+ P C+C T + G+ C+K +
Sbjct: 261 ECRCSYGWQGRFCDECVPYPGCVHGS-CVEPWQCNCETNWGGLLCDKDL 308
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 148 bits (374), Expect = 4e-35
Identities = 89/278 (32%), Positives = 118/278 (42%), Gaps = 30/278 (10%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNC---QTALCDPDCKNHGKCIKPNICQCLPGHGG 1354
C CG + E + C C+ G+ G C + DP C HG CI +C C+PG+ G
Sbjct: 563 CPVLCGGNGEYEKGH-CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKG 620
Query: 1355 ATCDEEHC-NPPCQHGGTCLAGNLCTCPYGFVGPRCET--MVCNRHCENGGQ-CLTPDIC 1410
C+EE C +P C + G C+ G C C G+ G CET VC C G L +C
Sbjct: 621 EICEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVC 679
Query: 1411 QCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR 1470
C P W G CST LC C + G C++ C C G+ G C+ CH C G C +
Sbjct: 680 SCDPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQC-K 737
Query: 1471 NNVCVCREGYTGRRFQ--------KSICDPTCMNGGKCVGPST---CSCPSGWSGKRCNT 1519
+ C C G+ G + C C G+C C C GWSG CN
Sbjct: 738 DGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Query: 1520 ---PICLQKCKNGG----ECIAPSICHCPSSWEGVRCQ 1550
+C N G +C+ P C + + CQ
Sbjct: 798 VMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 835
Score = 134 bits (337), Expect = 7e-31
Identities = 83/270 (30%), Positives = 107/270 (39%), Gaps = 24/270 (8%)
Query: 1330 CDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRC 1389
C +C +G+CI + C C PG G C + C C G G+ C C +G+ GP C
Sbjct: 532 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEKGH-CVCRHGWKGPEC 589
Query: 1390 ---ETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALC-DPVCLNGGSCNKPNTCLCP 1445
E + C G C+ +C C PG+ G C C DP+C N G C K C C
Sbjct: 590 DVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICVK-GECHCS 647
Query: 1446 NGFFGEHCQNAF--CHPPCKNGGHCMRN-NVCVCREGYTGRRFQKSICDPTCMNGGKCVG 1502
G+ G +C+ C C G + + VC C +TG +C C + G C
Sbjct: 648 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC-S 706
Query: 1503 PSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPI--------C 1554
C C GW G C C C G+C C C WEG C I C
Sbjct: 707 RGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHCTIAHYLDAVRDGC 765
Query: 1555 NPKCLYGGRCIFPN---VCSCRTEYSGVKC 1581
C GRC C C+ +SG C
Sbjct: 766 PGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 795
Score = 128 bits (321), Expect = 5e-29
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Query: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
+ C+ C G C++G+ C C GF+GP C C C G+ C C+ GW GP
Sbjct: 530 DDCSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGP 587
Query: 1420 TCSTA---LCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475
C DP C G+C C+C G+ GE C+ C P C N G C++ C
Sbjct: 588 ECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CH 645
Query: 1476 CREGYTGRRFQKS--ICDPTCMNGGK-CVGPSTCSCPSGWSGKRCNTPICLQKCKNGGEC 1532
C G+ G + +C C G + CSC W+G C+T +C +C + G C
Sbjct: 646 CSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC 705
Query: 1533 IAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
+ IC C W G C+ C+ C G+C C C + G C
Sbjct: 706 -SRGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHC 752
Score = 119 bits (299), Expect = 2e-26
Identities = 97/346 (28%), Positives = 124/346 (35%), Gaps = 73/346 (21%)
Query: 1131 LDSGPEGASVSSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNG---G 1187
+D GP + + G M + +LTT + + DDC E C C G
Sbjct: 500 MDQGPWYLAFYNDGKKMEQVFVLTT---AIEIMDDCSTNCNGNGECISGHCHCFPGFLGP 556
Query: 1188 SCVSDRN--FSPGSGVYL---CVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C D G+G Y CVC G+ G C+V C C G G+ I G C
Sbjct: 557 DCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----C 612
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
C P K E + +EED C P
Sbjct: 613 ICVPGYKGE--------------------ICEEED---------------------CLDP 631
Query: 1302 CGKSRECVAPNICKCKPGYIGSNCQTAL--CDPDCKNHGK-CIKPNICQCLPGHGGATCD 1358
+ C C G+ G NC+T L C C HG + +C C P G+ C
Sbjct: 632 MCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 691
Query: 1359 EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYG 1418
E C C G C G +C C G+VGP CE C+ HC GQC C+C PGW G
Sbjct: 692 TELCTMECGSHGVCSRG-ICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEG 749
Query: 1419 PTCSTAL--------CDPVCLNGGSCNKPNT---CLCPNGFFGEHC 1453
C+ A C +C G C C+C G+ G C
Sbjct: 750 DHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 795
Score = 94.7 bits (234), Expect = 6e-19
Identities = 53/167 (31%), Positives = 75/167 (44%), Gaps = 11/167 (6%)
Query: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRF 1485
C C G C + C C GF G C C C G + + CVCR G+ G
Sbjct: 532 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEKGH-CVCRHGWKGPEC 589
Query: 1486 ---QKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQK-CKNGGECIAPSICHCP 1541
++ DPTC G C+ C C G+ G+ C CL C N G C+ CHC
Sbjct: 590 DVPEEQCIDPTCFGHGTCI-MGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CHCS 647
Query: 1542 SSWEGVRCQ--IPICNPKCL-YGGRCIFPNVCSCRTEYSGVKCEKKI 1585
+ W GV C+ +P+C +C +G + VCSC +++G C ++
Sbjct: 648 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTEL 694
Score = 64.7 bits (156), Expect = 7e-10
Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 8/134 (5%)
Query: 1458 CHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRC 1517
C C G C+ + C C G+ G + C C G+ C C GW G C
Sbjct: 532 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGPEC 589
Query: 1518 NTPI--CLQK-CKNGGECIAPSICHCPSSWEGVRCQIPIC-NPKCLYGGRCIFPNVCSCR 1573
+ P C+ C G CI +C C ++G C+ C +P C G C+ C C
Sbjct: 590 DVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICV-KGECHCS 647
Query: 1574 TEYSGVKCEKKIQI 1587
T + GV CE + +
Sbjct: 648 TGWGGVNCETPLPV 661
Score = 40.0 bits (92), Expect = 0.018
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 12/74 (16%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC-----------SDSYDKAPEITELGNAG-FCDV 937
C C+GNG+C+ C C P F DC + Y+K + G G CDV
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 938 QKYNCMMVRVFGKG 951
+ C+ FG G
Sbjct: 592 PEEQCIDPTCFGHG 605
Score = 33.1 bits (74), Expect = 2.2
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 4/32 (12%)
Query: 890 CPNLCSGNGQCM----EWGCACSPSFSSYDCS 917
CP LC GNG+C W C C +S C+
Sbjct: 765 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 148 bits (374), Expect = 4e-35
Identities = 89/278 (32%), Positives = 118/278 (42%), Gaps = 30/278 (10%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNC---QTALCDPDCKNHGKCIKPNICQCLPGHGG 1354
C CG + E + C C+ G+ G C + DP C HG CI +C C+PG+ G
Sbjct: 562 CPVLCGGNGEYEKGH-CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKG 619
Query: 1355 ATCDEEHC-NPPCQHGGTCLAGNLCTCPYGFVGPRCET--MVCNRHCENGGQ-CLTPDIC 1410
C+EE C +P C + G C+ G C C G+ G CET VC C G L +C
Sbjct: 620 EICEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVC 678
Query: 1411 QCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR 1470
C P W G CST LC C + G C++ C C G+ G C+ CH C G C +
Sbjct: 679 SCDPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQC-K 736
Query: 1471 NNVCVCREGYTGRRFQ--------KSICDPTCMNGGKCVGPST---CSCPSGWSGKRCNT 1519
+ C C G+ G + C C G+C C C GWSG CN
Sbjct: 737 DGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796
Query: 1520 ---PICLQKCKNGG----ECIAPSICHCPSSWEGVRCQ 1550
+C N G +C+ P C + + CQ
Sbjct: 797 VMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 834
Score = 134 bits (337), Expect = 7e-31
Identities = 83/270 (30%), Positives = 107/270 (39%), Gaps = 24/270 (8%)
Query: 1330 CDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRC 1389
C +C +G+CI + C C PG G C + C C G G+ C C +G+ GP C
Sbjct: 531 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEKGH-CVCRHGWKGPEC 588
Query: 1390 ---ETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALC-DPVCLNGGSCNKPNTCLCP 1445
E + C G C+ +C C PG+ G C C DP+C N G C K C C
Sbjct: 589 DVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICVK-GECHCS 646
Query: 1446 NGFFGEHCQNAF--CHPPCKNGGHCMRN-NVCVCREGYTGRRFQKSICDPTCMNGGKCVG 1502
G+ G +C+ C C G + + VC C +TG +C C + G C
Sbjct: 647 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC-S 705
Query: 1503 PSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPI--------C 1554
C C GW G C C C G+C C C WEG C I C
Sbjct: 706 RGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHCTIAHYLDAVRDGC 764
Query: 1555 NPKCLYGGRCIFPN---VCSCRTEYSGVKC 1581
C GRC C C+ +SG C
Sbjct: 765 PGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794
Score = 128 bits (321), Expect = 5e-29
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Query: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
+ C+ C G C++G+ C C GF+GP C C C G+ C C+ GW GP
Sbjct: 529 DDCSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGP 586
Query: 1420 TCSTA---LCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475
C DP C G+C C+C G+ GE C+ C P C N G C++ C
Sbjct: 587 ECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CH 644
Query: 1476 CREGYTGRRFQKS--ICDPTCMNGGK-CVGPSTCSCPSGWSGKRCNTPICLQKCKNGGEC 1532
C G+ G + +C C G + CSC W+G C+T +C +C + G C
Sbjct: 645 CSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC 704
Query: 1533 IAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
+ IC C W G C+ C+ C G+C C C + G C
Sbjct: 705 -SRGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHC 751
Score = 119 bits (299), Expect = 2e-26
Identities = 97/346 (28%), Positives = 124/346 (35%), Gaps = 73/346 (21%)
Query: 1131 LDSGPEGASVSSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNG---G 1187
+D GP + + G M + +LTT + + DDC E C C G
Sbjct: 499 MDQGPWYLAFYNDGKKMEQVFVLTT---AIEIMDDCSTNCNGNGECISGHCHCFPGFLGP 555
Query: 1188 SCVSDRN--FSPGSGVYL---CVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C D G+G Y CVC G+ G C+V C C G G+ I G C
Sbjct: 556 DCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----C 611
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
C P K E + +EED C P
Sbjct: 612 ICVPGYKGE--------------------ICEEED---------------------CLDP 630
Query: 1302 CGKSRECVAPNICKCKPGYIGSNCQTAL--CDPDCKNHGK-CIKPNICQCLPGHGGATCD 1358
+ C C G+ G NC+T L C C HG + +C C P G+ C
Sbjct: 631 MCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 690
Query: 1359 EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYG 1418
E C C G C G +C C G+VGP CE C+ HC GQC C+C PGW G
Sbjct: 691 TELCTMECGSHGVCSRG-ICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEG 748
Query: 1419 PTCSTAL--------CDPVCLNGGSCNKPNT---CLCPNGFFGEHC 1453
C+ A C +C G C C+C G+ G C
Sbjct: 749 DHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794
Score = 94.7 bits (234), Expect = 6e-19
Identities = 53/167 (31%), Positives = 75/167 (44%), Gaps = 11/167 (6%)
Query: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRF 1485
C C G C + C C GF G C C C G + + CVCR G+ G
Sbjct: 531 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEKGH-CVCRHGWKGPEC 588
Query: 1486 ---QKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQK-CKNGGECIAPSICHCP 1541
++ DPTC G C+ C C G+ G+ C CL C N G C+ CHC
Sbjct: 589 DVPEEQCIDPTCFGHGTCI-MGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CHCS 646
Query: 1542 SSWEGVRCQ--IPICNPKCL-YGGRCIFPNVCSCRTEYSGVKCEKKI 1585
+ W GV C+ +P+C +C +G + VCSC +++G C ++
Sbjct: 647 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTEL 693
Score = 64.7 bits (156), Expect = 7e-10
Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 8/134 (5%)
Query: 1458 CHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRC 1517
C C G C+ + C C G+ G + C C G+ C C GW G C
Sbjct: 531 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGPEC 588
Query: 1518 NTPI--CLQK-CKNGGECIAPSICHCPSSWEGVRCQIPIC-NPKCLYGGRCIFPNVCSCR 1573
+ P C+ C G CI +C C ++G C+ C +P C G C+ C C
Sbjct: 589 DVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICV-KGECHCS 646
Query: 1574 TEYSGVKCEKKIQI 1587
T + GV CE + +
Sbjct: 647 TGWGGVNCETPLPV 660
Score = 40.0 bits (92), Expect = 0.018
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 12/74 (16%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC-----------SDSYDKAPEITELGNAG-FCDV 937
C C+GNG+C+ C C P F DC + Y+K + G G CDV
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 938 QKYNCMMVRVFGKG 951
+ C+ FG G
Sbjct: 591 PEEQCIDPTCFGHG 604
Score = 33.1 bits (74), Expect = 2.2
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 4/32 (12%)
Query: 890 CPNLCSGNGQCM----EWGCACSPSFSSYDCS 917
CP LC GNG+C W C C +S C+
Sbjct: 764 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 795
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 148 bits (374), Expect = 4e-35
Identities = 89/278 (32%), Positives = 118/278 (42%), Gaps = 30/278 (10%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNC---QTALCDPDCKNHGKCIKPNICQCLPGHGG 1354
C CG + E + C C+ G+ G C + DP C HG CI +C C+PG+ G
Sbjct: 563 CPVLCGGNGEYEKGH-CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKG 620
Query: 1355 ATCDEEHC-NPPCQHGGTCLAGNLCTCPYGFVGPRCET--MVCNRHCENGGQ-CLTPDIC 1410
C+EE C +P C + G C+ G C C G+ G CET VC C G L +C
Sbjct: 621 EICEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVC 679
Query: 1411 QCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR 1470
C P W G CST LC C + G C++ C C G+ G C+ CH C G C +
Sbjct: 680 SCDPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQC-K 737
Query: 1471 NNVCVCREGYTGRRFQ--------KSICDPTCMNGGKCVGPST---CSCPSGWSGKRCNT 1519
+ C C G+ G + C C G+C C C GWSG CN
Sbjct: 738 DGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Query: 1520 ---PICLQKCKNGG----ECIAPSICHCPSSWEGVRCQ 1550
+C N G +C+ P C + + CQ
Sbjct: 798 VMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 835
Score = 134 bits (337), Expect = 7e-31
Identities = 83/270 (30%), Positives = 107/270 (39%), Gaps = 24/270 (8%)
Query: 1330 CDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRC 1389
C +C +G+CI + C C PG G C + C C G G+ C C +G+ GP C
Sbjct: 532 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEKGH-CVCRHGWKGPEC 589
Query: 1390 ---ETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALC-DPVCLNGGSCNKPNTCLCP 1445
E + C G C+ +C C PG+ G C C DP+C N G C K C C
Sbjct: 590 DVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICVK-GECHCS 647
Query: 1446 NGFFGEHCQNAF--CHPPCKNGGHCMRN-NVCVCREGYTGRRFQKSICDPTCMNGGKCVG 1502
G+ G +C+ C C G + + VC C +TG +C C + G C
Sbjct: 648 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC-S 706
Query: 1503 PSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPI--------C 1554
C C GW G C C C G+C C C WEG C I C
Sbjct: 707 RGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHCTIAHYLDAVRDGC 765
Query: 1555 NPKCLYGGRCIFPN---VCSCRTEYSGVKC 1581
C GRC C C+ +SG C
Sbjct: 766 PGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 795
Score = 128 bits (321), Expect = 5e-29
Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Query: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
+ C+ C G C++G+ C C GF+GP C C C G+ C C+ GW GP
Sbjct: 530 DDCSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGP 587
Query: 1420 TCSTA---LCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475
C DP C G+C C+C G+ GE C+ C P C N G C++ C
Sbjct: 588 ECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CH 645
Query: 1476 CREGYTGRRFQKS--ICDPTCMNGGK-CVGPSTCSCPSGWSGKRCNTPICLQKCKNGGEC 1532
C G+ G + +C C G + CSC W+G C+T +C +C + G C
Sbjct: 646 CSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC 705
Query: 1533 IAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
+ IC C W G C+ C+ C G+C C C + G C
Sbjct: 706 -SRGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHC 752
Score = 119 bits (299), Expect = 2e-26
Identities = 97/346 (28%), Positives = 124/346 (35%), Gaps = 73/346 (21%)
Query: 1131 LDSGPEGASVSSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNG---G 1187
+D GP + + G M + +LTT + + DDC E C C G
Sbjct: 500 MDQGPWYLAFYNDGKKMEQVFVLTT---AIEIMDDCSTNCNGNGECISGHCHCFPGFLGP 556
Query: 1188 SCVSDRN--FSPGSGVYL---CVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241
C D G+G Y CVC G+ G C+V C C G G+ I G C
Sbjct: 557 DCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----C 612
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
C P K E + +EED C P
Sbjct: 613 ICVPGYKGE--------------------ICEEED---------------------CLDP 631
Query: 1302 CGKSRECVAPNICKCKPGYIGSNCQTAL--CDPDCKNHGK-CIKPNICQCLPGHGGATCD 1358
+ C C G+ G NC+T L C C HG + +C C P G+ C
Sbjct: 632 MCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 691
Query: 1359 EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYG 1418
E C C G C G +C C G+VGP CE C+ HC GQC C+C PGW G
Sbjct: 692 TELCTMECGSHGVCSRG-ICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEG 749
Query: 1419 PTCSTAL--------CDPVCLNGGSCNKPNT---CLCPNGFFGEHC 1453
C+ A C +C G C C+C G+ G C
Sbjct: 750 DHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 795
Score = 94.7 bits (234), Expect = 6e-19
Identities = 53/167 (31%), Positives = 75/167 (44%), Gaps = 11/167 (6%)
Query: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRF 1485
C C G C + C C GF G C C C G + + CVCR G+ G
Sbjct: 532 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEKGH-CVCRHGWKGPEC 589
Query: 1486 ---QKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQK-CKNGGECIAPSICHCP 1541
++ DPTC G C+ C C G+ G+ C CL C N G C+ CHC
Sbjct: 590 DVPEEQCIDPTCFGHGTCI-MGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CHCS 647
Query: 1542 SSWEGVRCQ--IPICNPKCL-YGGRCIFPNVCSCRTEYSGVKCEKKI 1585
+ W GV C+ +P+C +C +G + VCSC +++G C ++
Sbjct: 648 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTEL 694
Score = 64.7 bits (156), Expect = 7e-10
Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 8/134 (5%)
Query: 1458 CHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRC 1517
C C G C+ + C C G+ G + C C G+ C C GW G C
Sbjct: 532 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGPEC 589
Query: 1518 NTPI--CLQK-CKNGGECIAPSICHCPSSWEGVRCQIPIC-NPKCLYGGRCIFPNVCSCR 1573
+ P C+ C G CI +C C ++G C+ C +P C G C+ C C
Sbjct: 590 DVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICV-KGECHCS 647
Query: 1574 TEYSGVKCEKKIQI 1587
T + GV CE + +
Sbjct: 648 TGWGGVNCETPLPV 661
Score = 40.0 bits (92), Expect = 0.018
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 12/74 (16%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC-----------SDSYDKAPEITELGNAG-FCDV 937
C C+GNG+C+ C C P F DC + Y+K + G G CDV
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 938 QKYNCMMVRVFGKG 951
+ C+ FG G
Sbjct: 592 PEEQCIDPTCFGHG 605
Score = 33.1 bits (74), Expect = 2.2
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 4/32 (12%)
Query: 890 CPNLCSGNGQCM----EWGCACSPSFSSYDCS 917
CP LC GNG+C W C C +S C+
Sbjct: 765 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 145 bits (365), Expect = 4e-34
Identities = 110/342 (32%), Positives = 143/342 (41%), Gaps = 86/342 (25%)
Query: 1315 KCKPGYIGSNCQTALCDPDCKN---HGKCIKPNICQCLPGHGG----ATCDEEHCNPPCQ 1367
+C PG+ S +C P C + HG+CI PN CQC PG GG + CD +H P C
Sbjct: 93 QCCPGFYESG---EMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCT 149
Query: 1368 HGGTCLAGNLCT-------CPYGFVGPRCETMV--------CNR--HCENGGQC--LTPD 1408
C G LC C GF G RCE C++ C+NG C +T +
Sbjct: 150 SRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE 209
Query: 1409 ICQCKPGWYGPTCSTALCDP-----------VCLNGGSCNK-PNTCLCPNGFFGEHC--- 1453
C+C PG+ G C LC P C NGG C+ C CP+G+ G C
Sbjct: 210 -CRCPPGYTGAFCED-LCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQP 267
Query: 1454 -------QNAFCHPPCKNGGHC-MRNNVCVCREGYTGRRFQKS--------ICDPT--CM 1495
+N C NGG C C C GYTG R Q +C T C+
Sbjct: 268 CPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCV 327
Query: 1496 NGGKCVGPS-TCSCPSGWSGKRCNTPICLQ-----KCKNGGECIAPSI---------CHC 1540
NGGKC S C C +G++G+RC +C + KC C + C C
Sbjct: 328 NGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECAC 387
Query: 1541 PSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCE 1582
W G+ C C+P YG C +CSC+ +G C+
Sbjct: 388 KPGWSGLYCN-ETCSPG-FYGEAC--QQICSCQ---NGADCD 422
Score = 140 bits (354), Expect = 7e-33
Identities = 110/379 (29%), Positives = 149/379 (39%), Gaps = 100/379 (26%)
Query: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPD-----------CKNHGKCIK-PNI 1345
C C R C+APN C+C+PG+ G+NC +A CD D CKN C
Sbjct: 109 CADKCVHGR-CIAPNTCQCEPGWGGTNCSSA-CDGDHWGPHCTSRCQCKNGALCNPITGA 166
Query: 1346 CQCLPGHGGATCDEE----------HCNPPCQHGGTC--LAGNLCTCPYGFVGPRCETMV 1393
C C G G C++ H CQ+G TC + G C CP G+ G CE +
Sbjct: 167 CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE-CRCPPGYTGAFCEDLC 225
Query: 1394 --------CNRH--CENGGQC--LTPDICQCKPGWYGPTCSTAL--------CDPVCL-- 1431
C + C+NGG C +T + C C GW G C C C
Sbjct: 226 PPGKHGPQCEQRCPCQNGGVCHHVTGE-CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCH 284
Query: 1432 NGGSCN-KPNTCLCPNGFFGEHCQN--------AFCHPPCK--NGGHCMR-NNVCVCREG 1479
NGG+C+ C C G+ GE CQ+ C C+ NGG C + C+C G
Sbjct: 285 NGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAG 344
Query: 1480 YTGRRFQKSICDPTCMNGGKC---------------VGPSTCSCPSGWSGKRCNT----- 1519
+ G R + +C P + G KC C+C GWSG CN
Sbjct: 345 FAGERCEARLC-PEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPG 403
Query: 1520 ---PICLQ--KCKNGGEC-IAPSICHCPSSWEGVRCQIPI--------CNPKCLYGGRCI 1565
C Q C+NG +C C C ++G+ C P C+ +C +
Sbjct: 404 FYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAV 463
Query: 1566 FPNV---CSCRTEYSGVKC 1581
V C+C+ + GV C
Sbjct: 464 CSPVDGSCTCKAGWHGVDC 482
Score = 124 bits (312), Expect = 6e-28
Identities = 134/504 (26%), Positives = 181/504 (35%), Gaps = 141/504 (27%)
Query: 1181 CDCLNGGSC---VSDRNFSPGSGVYLC--VCLPGFHGSLCEVDISGCQSNPCGLGSYISG 1235
C C NG +C + PG C +C PG HG CE C G+ +++G
Sbjct: 195 CQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCE---QRCPCQNGGVCHHVTG 251
Query: 1236 FHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKN-----AQGRKRHVKP- 1289
C CP + ++ Q R K+ ++E N A + H P
Sbjct: 252 ----ECSCP------SGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPG 301
Query: 1290 -TSGNAFTICKYP-----CGKSRECV-------APNICKCKPGYIGSNCQTALCDP---- 1332
T C C ++ +CV C C+ G+ G C+ LC
Sbjct: 302 YTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYG 361
Query: 1333 -DCKNHGKCIKPNI---------CQCLPGHGGATCDEEHCNP-----------PCQHGGT 1371
C C N C C PG G C+E C+P CQ+G
Sbjct: 362 IKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNET-CSPGFYGEACQQICSCQNGAD 420
Query: 1372 C-LAGNLCTCPYGFVGPRCET--------MVCNRH--CENGGQCLTPD-ICQCKPGWYGP 1419
C CTC GF G C T + C+ C+N C D C CK GW+G
Sbjct: 421 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
Query: 1420 TCSTAL--------CDPV--CLNGGSCNK-PNTCLCPNGFFGEHCQNAFCHPPCKNGGHC 1468
CS C+ CLNGG+CN TC C G+ GE C+ PC++G +
Sbjct: 481 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCE-----LPCQDGTYG 535
Query: 1469 MRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPST--CSCPSGWSGKRCNTPICLQ-- 1524
+ C E CD C + C P+T C C GWSG C++ +C +
Sbjct: 536 LN-----CAER----------CD--CSHADGC-HPTTGHCRCLPGWSGVHCDS-VCAEGR 576
Query: 1525 ---------KCKNGGECIA-PSICHCPSSWEGVRCQIPICNPKCLYGGRCI--------- 1565
CKNG C IC C + G CQ IC+P YG RC
Sbjct: 577 WGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQ-RICSPG-FYGHRCSQTCPQCVHS 634
Query: 1566 ------FPNVCSCRTEYSGVKCEK 1583
+C C ++G C +
Sbjct: 635 SGPCHHITGLCDCLPGFTGALCNE 658
Score = 122 bits (305), Expect = 4e-27
Identities = 84/253 (33%), Positives = 108/253 (42%), Gaps = 62/253 (24%)
Query: 1393 VCNRHCENG---GQCLTPDICQCKPGWYGPTCSTALCDP-----------VCLNGGSCNK 1438
+C HC + G+C+ P+ CQC+PGW G CS+A CD C NG CN
Sbjct: 104 MCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSA-CDGDHWGPHCTSRCQCKNGALCNP 162
Query: 1439 -PNTCLCPNGFFGEHCQNAF--------CHP--PCKNGGHCMR-NNVCVCREGYTGRRFQ 1486
C C GF G C++ CH C+NG C C C GYTG F
Sbjct: 163 ITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTG-AFC 221
Query: 1487 KSICDP-----------TCMNGGKCVG-PSTCSCPSGWSGKRCNTPI--------CLQKC 1526
+ +C P C NGG C CSCPSGW G C P C Q+C
Sbjct: 222 EDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQEC 281
Query: 1527 K--NGGEC-IAPSICHCPSSWEGVRCQIP--------IC--NPKCLYGGRCI-FPNVCSC 1572
+ NGG C A CHC + G RCQ +C +C+ GG+C C C
Sbjct: 282 QCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLC 341
Query: 1573 RTEYSGVKCEKKI 1585
++G +CE ++
Sbjct: 342 EAGFAGERCEARL 354
Score = 118 bits (295), Expect = 5e-26
Identities = 136/521 (26%), Positives = 177/521 (33%), Gaps = 135/521 (25%)
Query: 1161 RLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDIS 1220
R D+C T + ++C C+NGG C SG C+C GF G CE +
Sbjct: 306 RCQDECPVGTYGVL--CAETCQCVNGGKCYHV------SGA--CLCEAGFAGERCEARLC 355
Query: 1221 GCQSNPCGLGSYISGFHSYSCD--CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDK 1278
G + CD CP L+ T + + + E
Sbjct: 356 P------------EGLYGIKCDKRCPCHLE-NTHSCHPMSGECACKPGWSGLYCNETCSP 402
Query: 1279 NAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL--------C 1330
G IC G + V C C PG+ G +C T C
Sbjct: 403 GFYGEACQ---------QICSCQNGADCDSVTGK-CTCAPGFKGIDCSTPCPLGTYGINC 452
Query: 1331 DP--DCKNHGKCIKPN-ICQCLPGHGGATCDEE--------HCNPPCQ--HGGTC-LAGN 1376
CKN C + C C G G C CN CQ +GG C
Sbjct: 453 SSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDG 512
Query: 1377 LCTCPYGFVGPRCET--------MVCNRHCENG---GQCLTPDICQCKPGWYGPTCSTAL 1425
CTC G+ G +CE + C C+ G T C+C PGW G C +
Sbjct: 513 TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVC 572
Query: 1426 CDP----------VCLNGGSCN------------KPNTC--LCPNGFFGEHCQNAFCHPP 1461
+ C NG SC+ + TC +C GF+G C C
Sbjct: 573 AEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQT-CPQC 631
Query: 1462 CKNGGHCMR-NNVCVCREGYTGR---------RFQKS---ICDPTCMNGGKCVG-PSTCS 1507
+ G C +C C G+TG RF K+ IC TC N G C +C
Sbjct: 632 VHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGIC--TCTNNGTCNPIDRSCQ 689
Query: 1508 CPSGWSGKRCNTPI--------CLQKCK--NGGECIA-PSICHCPSSWEGVRC--QIP-- 1552
C GW G C+ P C+ C NG C A C C W G+ C + P
Sbjct: 690 CYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLG 749
Query: 1553 --------ICNPKCLYGGRCI-FPNVCSCRTEYSGVKCEKK 1584
IC +C G C C+CRT + G CE+K
Sbjct: 750 FYGKDCALIC--QCQNGADCDHISGQCTCRTGFMGRHCEQK 788
Score = 73.9 bits (180), Expect = 1e-12
Identities = 79/287 (27%), Positives = 99/287 (34%), Gaps = 83/287 (28%)
Query: 1181 CDCLNGGSCVSDRNF---SPGSGVYLC--VCLPGFHGSLCEVDISGC--QSNPCGLGSYI 1233
C C NG SC D +PG C +C PGF+G C C S PC +I
Sbjct: 585 CYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPC---HHI 641
Query: 1234 SGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
+G CDC P F + R K N
Sbjct: 642 TGL----CDCLPG------FTGALCNEVCPSGRFGK-----------------------N 668
Query: 1294 AFTICKYPCGKSREC-VAPNICKCKPGYIGSNCQTALCDP-----------DCKNHGKCI 1341
IC C + C C+C PG+IGS+C C P +C N C
Sbjct: 669 CAGICT--CTNNGTCNPIDRSCQCYPGWIGSDCSQP-CPPAHWGPNCIHTCNCHNGAFCS 725
Query: 1342 K-PNICQCLPGHGGATCDE--------EHCNP--PCQHGGTC--LAGNLCTCPYGFVGPR 1388
C+C PG G C + + C CQ+G C ++G CTC GF+G
Sbjct: 726 AYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQ-CTCRTGFMGRH 784
Query: 1389 CETMV--------CNRHCE--NGGQC-LTPDICQCKPGWYGPTCSTA 1424
CE C + C+ N C C C PGW G C A
Sbjct: 785 CEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 142 bits (359), Expect = 2e-33
Identities = 130/463 (28%), Positives = 188/463 (40%), Gaps = 94/463 (20%)
Query: 1202 YLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISG-FHSYSCDCPPELKVETQFVNQFTTQ 1260
Y CVCL + G+ CE + + C+ NPC S + + SY C+C + +T Q
Sbjct: 755 YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCEC----------TSGWTGQ 804
Query: 1261 TVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTIC-----------KY--------P 1301
+ +N+ + D G H G +C +Y P
Sbjct: 805 -----NCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNP 859
Query: 1302 CGKSRECV----APNICKCKPGYIGSNCQTALCD---PDCKNHGKC---IKPNICQCLPG 1351
C + C+ A C C+ + G NC+ + D C+++G C + C C PG
Sbjct: 860 CRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPG 919
Query: 1352 HGGATCD---EEHCNPPCQHGGTCLAGN---LCTCPYGFVGPRCETMV--CN-RHCENGG 1402
G+ C+ E + PC++ GTC+ C C + GP CE V C C +
Sbjct: 920 FSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEE 979
Query: 1403 QCLTPD---ICQCKPGWYGPTC----STALCDPVCLNGGSC---NKPNTCLCPNGFFGEH 1452
C+ C C PG+ G C L +P CL+ G C TC C +GFFG H
Sbjct: 980 NCVYRTDGYNCLCAPGYTGINCEINLDECLSEP-CLHDGVCIDGINHYTCDCKSGFFGTH 1038
Query: 1453 CQ---NAFCHPPCKNG--GHCMRNNVCVCREGYTGRRFQKSICDPT---CMNGGKCVGPS 1504
C+ N PC +G + C C T + + I D T CMN G C +
Sbjct: 1039 CETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA 1098
Query: 1505 ---TCSCPSGWSGKRCNTPI--CLQK------CKNGGECI-APS---ICHCPSSWEGVRC 1549
TC CP G++G C I C + C NGG C+ P C C + G C
Sbjct: 1099 HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFC 1158
Query: 1550 QIPI---CNPKCLYGGRC---IFPNVCSCRTEYSGVKCEKKIQ 1586
+I I + CL+G C I VC C+ +SG CE +++
Sbjct: 1159 EININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE 1201
Score = 137 bits (346), Expect = 6e-32
Identities = 132/478 (27%), Positives = 188/478 (39%), Gaps = 78/478 (16%)
Query: 1179 KSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLG-SYISGFH 1237
KS C NG + R G + C+PGF G+ CE+DI C S+PC G + I
Sbjct: 648 KSASCKNGTTSTHLR------GYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPG 701
Query: 1238 SYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNK---EEDDKNAQGRKRH-------V 1287
+Y C C P KV F + V R ++ ++ + N+ + H +
Sbjct: 702 NYFCQCVPPFKVVDGF-SCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCL 760
Query: 1288 KPTSGN----AFTICKY-PCGKSRECV---APNICKCKPGYIGSNCQTAL--CDPD-CKN 1336
GN CK PC + C C+C G+ G NC + CD D C N
Sbjct: 761 SDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMN 820
Query: 1337 HGKCIKPNI-----CQCLPGHGGATCDEEH-----CNPPCQHGGTCL----AGNLCTCPY 1382
G C + I C C P + G C + + + PC++ TCL A C C
Sbjct: 821 GGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICRE 880
Query: 1383 GFVGPRCETMVCN---RHCENGGQC---LTPDICQCKPGWYGPTCSTAL---CDPVCLNG 1433
F G CE V + C++ G C + C C+PG+ G C + C N
Sbjct: 881 EFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNN 940
Query: 1434 GSC---NKPNTCLCPNGFFGEHCQ---NAFCHPPCKNGGHCMRNN---VCVCREGYTGRR 1484
G+C C C + G C+ N PC + +C+ C+C GYTG
Sbjct: 941 GTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGIN 1000
Query: 1485 FQKSI---CDPTCMNGGKC---VGPSTCSCPSGWSGKRCNTPI--CLQK-CKNG--GECI 1533
+ ++ C++ G C + TC C SG+ G C T CL C +G E I
Sbjct: 1001 CEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELI 1060
Query: 1534 APSICHCPSSWEGVRCQIPI---CNPKCLYGGRC---IFPNVCSCRTEYSGVKCEKKI 1585
C C + +C+I I + C+ G C C C Y+G CEK I
Sbjct: 1061 NEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
Score = 134 bits (336), Expect = 9e-31
Identities = 189/815 (23%), Positives = 297/815 (36%), Gaps = 160/815 (19%)
Query: 894 CSGNGQCME---------WGCACSPSFSSYDCSDSYDKA-PEITELGNAGFCDVQKYNCM 943
C NG C+ + C C P F+ +CS+ + P + GN + C
Sbjct: 222 CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICE 281
Query: 944 MVRVFGKGFKELPSIKCEVTKLQYNSSEWMPGEPIYTQTVFHNSRAVDCQLPTDVQQFDT 1003
F F E+ + C V+ L + YT S + + + TDV +F
Sbjct: 282 CDEQFSGPFCEVSAKPC-VSLLFWKRGICPNSSSAYTYECPKGSSSQNGE--TDVSEFSL 338
Query: 1004 MDLVGGKPTGKWQLKVSNDGYKFSNPKITVI----YDGACQVCGLYKNDSC--TIKENVC 1057
+ G +K+SND +P T + +C+ L N +C K+ C
Sbjct: 339 VPCQNGTDC----IKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPC 394
Query: 1058 -IIDGLC------YVEGDKNPTSPCL--------------ICRPKISRFTWSFLENNQPP 1096
I G ++ K + CL +C P ++ FL+N
Sbjct: 395 SCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVY-L 453
Query: 1097 VIQALQDKLQTFYG-------ENFEYQFVAFDPEGSDIHFTLDSGPEGASVSSAGLFMWK 1149
+ Q L TF+G FEY + + F G + V A F+
Sbjct: 454 IHQHLCYCGVTFHGICQDKGPAQFEYVW--------QLGFAGSEGEKCQGVIDAYFFLAA 505
Query: 1150 TDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPG 1209
T+ T +ND D + C NG SC+S+ + S Y +C
Sbjct: 506 N---CTEDATY-VNDPEDNNSSCWFPHEGTKEICANGCSCLSEED----SQEYRYLCFLR 557
Query: 1210 FHGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCP---PELKVETQFVNQFTTQTVVLTR 1266
+ G++ + + Q N C H C P ++ + V
Sbjct: 558 WAGNMYLENTTDDQENECQ--------HEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCL 609
Query: 1267 SDKSVNKE------EDDKNAQGRKRHVKPTSGNAFTICKYPCGK----SRECVAPNICKC 1316
+ S++ + N G +R+ + CK K S KC
Sbjct: 610 GNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKC 669
Query: 1317 KPGYIGSNCQTAL---CDPDCKNHGKCI-KPN--ICQCL--------------PGHGGAT 1356
PG+ G+ C+ + CKN CI +P CQC+ PG+ G
Sbjct: 670 VPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIR 729
Query: 1357 CDEEHCN---PPCQHGGTCLAGNL---CTCPYGFVGPRC--ETMVCNRH-CENGGQCLTP 1407
C+++ + C+H TC +L C C + G C E+ C + C+N C
Sbjct: 730 CEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTC--T 787
Query: 1408 DI-----CQCKPGWYGPTCSTAL--CD-PVCLNGGSCNKPN-----TCLCPNGFFGEHCQ 1454
D+ C+C GW G CS + CD C+NGG C++ CLCP + G+ C
Sbjct: 788 DLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCH 847
Query: 1455 NAF-----CHPPCKNGGHCM----RNNVCVCREGYTGRRFQKSICD---PTCMNGGKC-- 1500
+ H PC+N C+ N C+CRE + G+ + + D +C + G C
Sbjct: 848 QRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCED 907
Query: 1501 -VGPSTCSCPSGWSGKRCNTPI---CLQKCKNGGECIAPS---ICHCPSSWEGVRCQIPI 1553
V C C G+SG C I + CKN G C+ + C+C + G C++ +
Sbjct: 908 MVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDV 967
Query: 1554 CNPK---CLYGGRCIFPN---VCSCRTEYSGVKCE 1582
K CL C++ C C Y+G+ CE
Sbjct: 968 NKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCE 1002
Score = 110 bits (276), Expect = 8e-24
Identities = 98/355 (27%), Positives = 137/355 (38%), Gaps = 64/355 (18%)
Query: 1175 EVTVKSC---DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC-GLG 1230
E+ VK C C + G C N + C+C PGF GSLCE++I+ C S PC G
Sbjct: 888 EIDVKDCLFLSCQDYGDCEDMVNN------FRCICRPGFSGSLCEIEINECSSEPCKNNG 941
Query: 1231 SYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKP- 1289
+ + + + C+C PE + F V + +++E G P
Sbjct: 942 TCVDLTNRFFCNCEPE------YHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPG 995
Query: 1290 -----TSGNAFTICKYPCGKSREC---VAPNICKCKPGYIGSNCQTALCDPDCKN----H 1337
N PC C + C CK G+ G++C+T DC + H
Sbjct: 996 YTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNA--NDCLSNPCLH 1053
Query: 1338 GKC---IKPNICQCLPGHGGATCD---EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPR 1388
G+C I C C C + + PC + G C G C CP G+ G
Sbjct: 1054 GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAY 1113
Query: 1389 CETMVCNRH--------CENGGQCL-----TPDICQCKPGWYGPTCSTAL---CDPVCLN 1432
CE + N C NGG C+ T D C+C PG+ G C + CL+
Sbjct: 1114 CEKSIDNCAEPELNSVICLNGGICVDGPGHTFD-CRCLPGFSGQFCEININECSSSPCLH 1172
Query: 1433 GGSCN---KPNTCLCPNGFFGEHCQNAF-CHPPCKNGGHCMRN---NVCVCREGY 1480
G C C C G+ G HC+N C P CM N + C+C G+
Sbjct: 1173 GADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGF 1227
Score = 96.3 bits (238), Expect = 2e-19
Identities = 89/324 (27%), Positives = 131/324 (40%), Gaps = 49/324 (15%)
Query: 1154 TTQQITVRLNDDCDAETRVTI-EVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHG 1212
T +T R +C+ E E+ V C C+ + N + Y C+C PG+ G
Sbjct: 942 TCVDLTNRFFCNCEPEYHGPFCELDVNKCKI---SPCLDEENCVYRTDGYNCLCAPGYTG 998
Query: 1213 SLCEVDISGCQSNPC-GLGSYISGFHSYSCDCPPEL---KVETQFVNQFTTQTVVLTRSD 1268
CE+++ C S PC G I G + Y+CDC ET N + + R
Sbjct: 999 INCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETN-ANDCLSNPCLHGRCT 1057
Query: 1269 KSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPC---GKSRECVAPNICKCKPGYIGSNC 1325
+ +N+ +A G K + +I PC G ++ C C GY G+ C
Sbjct: 1058 ELINEYPCSCDADGTSTQCKIKINDCTSI---PCMNEGFCQKSAHGFTCICPRGYTGAYC 1114
Query: 1326 QTAL---CDPD-----CKNHGKCI----KPNICQCLPGHGGATCD---EEHCNPPCQHGG 1370
+ ++ +P+ C N G C+ C+CLPG G C+ E + PC HG
Sbjct: 1115 EKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGA 1174
Query: 1371 TC---LAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCD 1427
C + G +C C G+ G HCEN +C+ P+ C + ST LC
Sbjct: 1175 DCEDHINGYVCKCQPGWSG---------HHCENELECI-PNSCVHELCMENEPGSTCLCT 1224
Query: 1428 P---VCLNGGSCN---KPNTCLCP 1445
P C G C + TCL P
Sbjct: 1225 PGFMTCSIGLLCGDEIRRITCLTP 1248
Score = 78.2 bits (191), Expect = 6e-14
Identities = 70/237 (29%), Positives = 98/237 (41%), Gaps = 41/237 (17%)
Query: 1325 CQTALCDPDCKNHGKCI-----KPNICQCLPGHGGATCDE-EHCN-PPCQHGGTCL---- 1373
CQ +L C HGKC+ K C C P G C E + C+ PC++ G+C+
Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
Query: 1374 ----AGNLCTCPYGFVGPRCETMV--CNRHCENGGQC--LTPD--ICQCKPGWYGPTCST 1423
C C F G C ++ C H G C +T + IC+C + GP C
Sbjct: 234 NWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEV 293
Query: 1424 ALCDPVCL---NGGSC---NKPNTCLCPNGFF---GEHCQNAFCHPPCKNGGHCMR--NN 1472
+ V L G C + T CP G GE + F PC+NG C++ N+
Sbjct: 294 SAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISND 353
Query: 1473 V-CVCREGYTG---RRFQKSICDPTCMNGG----KCVGPSTCSCPSGWSGKRCNTPI 1521
V C+C +T + Q S C+ + KC CSC SG++ K C I
Sbjct: 354 VMCICSPIFTDLLCKSIQTS-CESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI 409
Score = 55.1 bits (131), Expect = 5e-07
Identities = 63/248 (25%), Positives = 83/248 (33%), Gaps = 74/248 (29%)
Query: 1314 CKCKPGYIGSNCQT--ALCDPDCKNHGKCIKPNI--------CQCLPGHGGATCDE--EH 1361
C C+P + G CQ A CKN+G CI C C P G C E
Sbjct: 200 CHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQ 259
Query: 1362 CNPPCQHGGTC--LAGN--LCTCPYGFVGPRCE------------------------TMV 1393
C P G C + N +C C F GP CE T
Sbjct: 260 CQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYE 319
Query: 1394 CNRH-----------------CENGGQCLTPD---ICQCKPGWYGPTCST--ALCDPVCL 1431
C + C+NG C+ +C C P + C + C+ L
Sbjct: 320 CPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPL 379
Query: 1432 NGGS----CNKPNTCLCPNGFFGEHCQNAFCHPPCK-NGGHCMRNNVCVCREGYTGRRFQ 1486
+ C K C C +GF ++C+ A H CK +C+ C G RF
Sbjct: 380 RNNATCKKCEKDYPCSCISGFTEKNCEKAIDH--CKLLSINCLNEEWCFNIIG----RF- 432
Query: 1487 KSICDPTC 1494
K +C P C
Sbjct: 433 KYVCIPGC 440
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/75 (37%), Positives = 36/75 (48%), Gaps = 9/75 (12%)
Query: 1324 NCQTALCDPD-CKNHGKCIKPN---ICQCLPGHGGATCDEEHC-NPPCQHGGTCLAGN-- 1376
NC C C+N+G CI N C+C + G C C N PC +G TC+ +
Sbjct: 2333 NCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGT 2392
Query: 1377 --LCTCPYGFVGPRC 1389
+C CPYG GP C
Sbjct: 2393 DIVCLCPYGRSGPLC 2407
Score = 49.7 bits (117), Expect = 2e-05
Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 21/118 (17%)
Query: 1486 QKSICDPTCMNGGKCVGPS-----TCSCPSGWSGKRCNT--PICLQKCKNGGECIAPS-- 1536
Q+S+ C GKC+ + +C C +SGK C + CKN G CI
Sbjct: 175 QESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKREN 234
Query: 1537 --------ICHCPSSWEGVRCQIPICNPKCLYGGRC--IFPN--VCSCRTEYSGVKCE 1582
+CH P + + I C P + G C I N +C C ++SG CE
Sbjct: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
Score = 48.9 bits (115), Expect = 4e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 14/80 (17%)
Query: 1360 EHCNPP------CQHGGTCLAGN---LCTCPYGFVGPRCETMVC-NRHCENGGQCL---- 1405
E+C+ P C++ GTC++ N C CP + G C+ C N C NG C+
Sbjct: 2332 ENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSG 2391
Query: 1406 TPDICQCKPGWYGPTCSTAL 1425
T +C C G GP C+ A+
Sbjct: 2392 TDIVCLCPYGRSGPLCTDAI 2411
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 1389 CETMVCNRH-CENGGQCL---TPDICQCKPGWYGPTC--STALCDPVCLNGGSC----NK 1438
C+ C + C NGG+C T C+C P W G TC S + + +CL+ C +
Sbjct: 2874 CDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSF 2933
Query: 1439 PNTCLCPNGFFGEHCQN 1455
+CLC G+ G +C+N
Sbjct: 2934 SYSCLCTLGWVGRYCEN 2950
Score = 48.1 bits (113), Expect = 7e-05
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 9/89 (10%)
Query: 1451 EHCQNAFC-HPPCKNGGHCMRNN---VCVCREGYTGRRFQKSICDPT-CMNGGKCVGPS- 1504
E+C +C H C+N G C+ +N C C Y+G+ Q + C+ C NG CV S
Sbjct: 2332 ENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSG 2391
Query: 1505 ---TCSCPSGWSGKRCNTPICLQKCKNGG 1530
C CP G SG C I + + + G
Sbjct: 2392 TDIVCLCPYGRSGPLCTDAINITQPRFSG 2420
Score = 47.8 bits (112), Expect = 9e-05
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 15/84 (17%)
Query: 1388 RCETMVCN-RHCENGGQCL---TPDICQCKPGWYGPTCSTAL--CDPV------CLNGGS 1435
+C C+ C NGG C+ T C C GW G C+ + CDP C G +
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 1436 C-NKPN--TCLCPNGFFGEHCQNA 1456
C + P+ TC CP G G +C+ A
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCEQA 2691
Score = 46.6 bits (109), Expect = 2e-04
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 15/93 (16%)
Query: 1510 SGWSGKRCN-TPICLQKCKNGGECIAPS---ICHCPSSWEGVRC--QIPICNPK------ 1557
+G S +C+ +P L KC NGG CI C+C + W+G C + C+P+
Sbjct: 2602 AGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH 2661
Query: 1558 CLYGGRCI-FPN--VCSCRTEYSGVKCEKKIQI 1587
C G CI P+ C C +G+ CE+ + I
Sbjct: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCEQALSI 2694
Score = 45.4 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 36/82 (43%), Gaps = 17/82 (20%)
Query: 1325 CQTALCD-PDCKNHGKCIKPNI---CQCLPGHGGA-------TCDEEHCNPP--CQHGGT 1371
C + C C N G CI+ C C G G+ TCD EH +PP C G T
Sbjct: 2609 CHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH-DPPHHCSRGAT 2667
Query: 1372 CLA---GNLCTCPYGFVGPRCE 1390
C++ G C CP G G CE
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCE 2689
Score = 43.9 bits (102), Expect = 0.001
Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 9/82 (10%)
Query: 1515 KRCNTPICLQK-CKNGGECIAPS---ICHCPSSWEGVRCQIPIC-NPKCLYGGRCIFPN- 1568
+ C+ P C C+N G CI+ + C CP + G CQ C N C G C+ +
Sbjct: 2332 ENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSG 2391
Query: 1569 ---VCSCRTEYSGVKCEKKIQI 1587
VC C SG C I I
Sbjct: 2392 TDIVCLCPYGRSGPLCTDAINI 2413
Score = 42.0 bits (97), Expect = 0.005
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 1389 CETMVCNRH-CENGGQCLTPD---ICQCKPGWYGPTCSTALCDP-VCLNGGSCNKPN--- 1440
C C H C N G C++ + C+C + G C A C+ C NG +C +
Sbjct: 2334 CHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTD 2393
Query: 1441 -TCLCPNGFFGEHCQNA 1456
CLCP G G C +A
Sbjct: 2394 IVCLCPYGRSGPLCTDA 2410
Score = 42.0 bits (97), Expect = 0.005
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 8/62 (12%)
Query: 1429 VCLNGGSCNKPNT---CLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNN----VCVCREGY 1480
+C N G+C N C CP + G+ CQ A C + PC NG C+ + VC+C G
Sbjct: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGR 2402
Query: 1481 TG 1482
+G
Sbjct: 2403 SG 2404
Score = 42.0 bits (97), Expect = 0.005
Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 8/64 (12%)
Query: 1494 CMNGGKCVGPST---CSCPSGWSGKRCNTPICLQK-CKNGGECIAPS----ICHCPSSWE 1545
C N G C+ + C CP +SGK C C C NG C+ S +C CP
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS 2403
Query: 1546 GVRC 1549
G C
Sbjct: 2404 GPLC 2407
Score = 41.6 bits (96), Expect = 0.006
Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 14/71 (19%)
Query: 1494 CMNGGKCVGPST---CSCPSGWSGKRCNTPICL--------QKCKNGGECIA---PSICH 1539
C NGG C+ T C+C +GW G C + C G CI+ C
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 1540 CPSSWEGVRCQ 1550
CP G+ C+
Sbjct: 2679 CPLGTTGIYCE 2689
Score = 41.2 bits (95), Expect = 0.008
Identities = 65/291 (22%), Positives = 101/291 (34%), Gaps = 70/291 (24%)
Query: 1166 CDAETRVTIEVTVKSCD-------CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVD 1218
C R+ + V + C C G C+S+ S Y C C P F G C+ +
Sbjct: 159 CPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEA----WSKTYSCHCQPPFSGKYCQ-E 213
Query: 1219 ISGCQSNPC-GLGSYIS-----GFHSYSCDCPPEL--KVETQFVNQF------------T 1258
+ C PC GS I+ +Y C C P K ++ + Q
Sbjct: 214 LDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI 273
Query: 1259 TQTVVLTRSDKSVNKEEDDKNAQG------RKRHVKPTSGNAFTICKYPCGKSRECVAPN 1312
T + D+ + + +A+ KR + P S +A+T
Sbjct: 274 TSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTY--------------- 318
Query: 1313 ICKCKPGYIGSNCQTALCD---PDCKNHGKCIKPN---ICQCLPGHGGATCD--EEHCNP 1364
+C G N +T + + C+N CIK + +C C P C + C
Sbjct: 319 --ECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCES 376
Query: 1365 -PCQHGGTCLAGNL---CTCPYGFVGPRCETMVCNRHCE-NGGQCLTPDIC 1410
P ++ TC C+C GF CE + HC+ CL + C
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI--DHCKLLSINCLNEEWC 425
Score = 40.8 bits (94), Expect = 0.011
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQ-----SNPCGLG-SYISGF 1236
C NGG+C+ G+ VY C C G+ GS C +S C + C G + IS
Sbjct: 2619 CGNGGTCIES-----GTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP 2672
Query: 1237 HSYSCDCP 1244
H Y+C CP
Sbjct: 2673 HGYTCFCP 2680
Score = 40.0 bits (92), Expect = 0.018
Identities = 28/82 (34%), Positives = 36/82 (43%), Gaps = 13/82 (15%)
Query: 1322 GSN---CQTALCDPD-CKNHGKCIKPNI---CQCLPGHGGATCDEE-HC-NPPCQHGGTC 1372
GSN C C + C+N G+C C+CLP G TC++ C N C H C
Sbjct: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLC 2927
Query: 1373 LAGN----LCTCPYGFVGPRCE 1390
+ C C G+VG CE
Sbjct: 2928 IPDQSFSYSCLCTLGWVGRYCE 2949
Score = 39.7 bits (91), Expect = 0.023
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 1493 TCMNGGKCVGPST---CSCPSGWSGKRCNTPI-CLQK-CKNGGECIAPS----ICHCPSS 1543
TC NGG+C T C C W+G CN + CL C + CI C C
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
Query: 1544 WEGVRCQ 1550
W G C+
Sbjct: 2943 WVGRYCE 2949
Score = 37.0 bits (84), Expect = 0.15
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 14/76 (18%)
Query: 1462 CKNGGHCMRNNV---CVCREGYTGRRFQKSI--CDPT------CMNGGKCVGPS---TCS 1507
C NGG C+ + C C G+ G +++ CDP C G C+ TC
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 1508 CPSGWSGKRCNTPICL 1523
CP G +G C + +
Sbjct: 2679 CPLGTTGIYCEQALSI 2694
Score = 37.0 bits (84), Expect = 0.15
Identities = 21/85 (24%), Positives = 32/85 (37%), Gaps = 10/85 (11%)
Query: 1453 CQNAFC-HPPCKNGGHCMRNNV---CVCREGYTGRRFQKSIC--DPTCMNGGKCVGPST- 1505
C C + C+NGG C N C C + G +S+ + C++ C+ +
Sbjct: 2874 CDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSF 2933
Query: 1506 ---CSCPSGWSGKRCNTPICLQKCK 1527
C C GW G+ C K
Sbjct: 2934 SYSCLCTLGWVGRYCENKTSFSTAK 2958
Score = 36.6 bits (83), Expect = 0.20
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 8/49 (16%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGS 1231
C N G+C+SD C C + G LC+ + C++NPCG G+
Sbjct: 2344 CRNNGTCISDNEN------LFCECPRLYSGKLCQ--FASCENNPCGNGA 2384
Score = 35.4 bits (80), Expect = 0.44
Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 8/66 (12%)
Query: 1302 CGKSRECVAPN---ICKCKPGYIGSNCQTALCDPD-CKNHGKCIKPN----ICQCLPGHG 1353
C + C++ N C+C Y G CQ A C+ + C N C+ + +C C G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS 2403
Query: 1354 GATCDE 1359
G C +
Sbjct: 2404 GPLCTD 2409
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 142 bits (359), Expect = 2e-33
Identities = 90/283 (31%), Positives = 126/283 (44%), Gaps = 45/283 (15%)
Query: 1314 CKCKPGYIGSNCQT--ALCDPDCKNHGKCIKPN--------ICQCLPGHGGATCDE--EH 1361
C C+ Y+G+ C+ A C+N+ CI N C CLPG+ G C ++
Sbjct: 336 CTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDY 395
Query: 1362 CN-PPCQHGGTC---LAGNLCTCPYGFVGPRCETMV---CNRHCENGGQCLTPDI---CQ 1411
C PC++G TC L+G C CP G+ G CE V + C+N G C + C
Sbjct: 396 CILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCN 455
Query: 1412 CKPGWYGPTCSTAL--CDPVCLNGGSCNKPNT---CLCPNGFFGEHCQ---NAFCHPPCK 1463
C PG+ GPTC+ + C G+C T CLC G+ G +C+ N PC
Sbjct: 456 CSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCL 515
Query: 1464 NGGHC---MRNNVCVCREGYTGRR---FQKSICDPTCMNGGKCVGPS---TCSCPSGWSG 1514
N C + CVC Y G ++ + +C+NG C TC C G++G
Sbjct: 516 NAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTG 575
Query: 1515 KRCNTPI--C-LQKCKNGGECIAPSI---CHCPSSWEGVRCQI 1551
+ C+ I C C +GG C+ CHCP W G C+I
Sbjct: 576 EECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 96.7 bits (239), Expect = 2e-19
Identities = 83/343 (24%), Positives = 131/343 (38%), Gaps = 51/343 (14%)
Query: 1151 DLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGF 1210
D +T + +RL T V E +C G C + P + C C +
Sbjct: 287 DSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTT----KPSEATFSCTCEEQY 342
Query: 1211 HGSLCEVDISGCQSNPCGLGSYISGFH------SYSCDCPP-------ELKVETQFVNQF 1257
G+ CE + CQ PC + + +++C C P + K++ ++
Sbjct: 343 VGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPC 401
Query: 1258 TTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNI---C 1314
++ + + + V P + + PC + C + C
Sbjct: 402 RNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS-------PCQNNGTCYVDGVHFTC 454
Query: 1315 KCKPGYIGSNCQTAL--CDPDCKNHGKCIKPNI---CQCLPGHGGATCDEEH---CNPPC 1366
C PG+ G C + C HG C C C PG+ G C+EE+ + PC
Sbjct: 455 NCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPC 514
Query: 1367 QHGGTC---LAGNLCTCPYGFVGPRCETM---VCNRHCENGGQCLTPDI---CQCKPGWY 1417
+ TC + G C C + G CE N C NG C + + C C PG+
Sbjct: 515 LNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFT 574
Query: 1418 GPTCSTAL--CDP-VCLNGGSC-NKPN--TCLCPNGFFGEHCQ 1454
G C + CD C +GGSC ++PN C CP+G+ G +C+
Sbjct: 575 GEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 92.4 bits (228), Expect = 3e-18
Identities = 76/270 (28%), Positives = 100/270 (37%), Gaps = 34/270 (12%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSY-ISGFHSYSC 1241
C N SC+ GS + CVCLPG+ G LC+ I C +PC G+ IS ++C
Sbjct: 358 CQNNASCIDANEKQDGSN-FTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTC 416
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNK-----EEDDKNAQGRKRHVKPTSGNAFT 1296
CP + + V S N + PT
Sbjct: 417 QCPEG------YFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLID 470
Query: 1297 ICKY-PC--GKSRECVAPNICKCKPGYIGSNCQ---TALCDPDCKNHGKC---IKPNICQ 1347
C PC G R C C PGY G C+ C N C + C
Sbjct: 471 FCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECV 530
Query: 1348 CLPGHGGATCD--EEHC-NPPCQHGGTCLAGNL---CTCPYGFVGPRCETMV--CNRH-C 1398
CL + G C+ ++ C N C +G TC + L C C GF G C+ + C+ + C
Sbjct: 531 CLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPC 590
Query: 1399 ENGGQCLTPDI---CQCKPGWYGPTCSTAL 1425
+GG CL C C GW G C L
Sbjct: 591 HHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
Score = 80.1 bits (196), Expect = 2e-14
Identities = 77/276 (27%), Positives = 100/276 (36%), Gaps = 76/276 (27%)
Query: 1345 ICQCLPGHGGATCDEEHCNP-PCQHGGTCL-----AGNLCTCPYGFVGPRCETMVCNRHC 1398
+ C+PG E H N C G C A CTC +VG CE
Sbjct: 304 VSTCVPG-------ESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY------ 350
Query: 1399 ENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN--------TCLCPNGFFG 1450
D CQ KP C N SC N TC+C G+ G
Sbjct: 351 ---------DACQRKP---------------CQNNASCIDANEKQDGSNFTCVCLPGYTG 386
Query: 1451 EHCQNAFCH---PPCKNGGHCMRNN---VCVCREGYTGRRFQKSICDPT----CMNGGKC 1500
E CQ+ + PC+NG C+ + C C EGY G ++ + DP C N G C
Sbjct: 387 ELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKV-DPCASSPCQNNGTC 445
Query: 1501 VGPS---TCSCPSGWSGKRCNTPI---CLQKCKNGG-ECIAPSI-CHCPSSWEGVRCQIP 1552
TC+C G++G C I L C +G + S C C + G+ C+
Sbjct: 446 YVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEE 505
Query: 1553 I---CNPKCLYGGRC---IFPNVCSCRTEYSGVKCE 1582
+ CL C + C C EY G CE
Sbjct: 506 YNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCE 541
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/120 (27%), Positives = 47/120 (39%), Gaps = 11/120 (9%)
Query: 1310 APNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNI-CQCLPGHGGATCD---EEHCNPP 1365
AP C +P G C T+ +PD ++ +P C C G GA C + + P
Sbjct: 44 APGPCAAQPCRNGGVC-TSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNP 102
Query: 1366 CQHGGTCLA------GNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
C HG + G LC C G+ GP CE + + + + P Q P P
Sbjct: 103 CHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEP 162
Score = 43.1 bits (100), Expect = 0.002
Identities = 43/169 (25%), Positives = 57/169 (33%), Gaps = 63/169 (37%)
Query: 1427 DPVCLNGGSCN-KPN----TCLCPNGFFGEHCQ--NAFCHPPCKNGGHCMRNNVCVCREG 1479
D C G C KP+ +C C + G C+ +A PC+N C+ N E
Sbjct: 316 DLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDAN-----EK 370
Query: 1480 YTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPI---CLQKCKNGGECIAPS 1536
G F TC C G++G+ C + I L C+NG CI
Sbjct: 371 QDGSNF-------------------TCVCLPGYTGELCQSKIDYCILDPCRNGATCI--- 408
Query: 1537 ICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKI 1585
SS G CQ C Y G CE+K+
Sbjct: 409 -----SSLSGFTCQ---------------------CPEGYFGSACEEKV 431
Score = 41.2 bits (95), Expect = 0.008
Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 24/85 (28%)
Query: 1365 PCQHGGTCLA---------------GNLCTCPYGFVGPRCETMV--CNRHCENGGQCLTP 1407
PC++GG C + G CTCP G G C+ + C + + G C +
Sbjct: 52 PCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSS 111
Query: 1408 D-------ICQCKPGWYGPTCSTAL 1425
+C C G+ GP C AL
Sbjct: 112 SSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 41.2 bits (95), Expect = 0.008
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 10/71 (14%)
Query: 1183 CLNGGSCVSDRNFSP------GSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGF 1236
C NGG C S P G Y C C G G+ C++ C SNPC G+ S
Sbjct: 53 CRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSS 112
Query: 1237 HS----YSCDC 1243
S Y C C
Sbjct: 113 SSSSDGYLCIC 123
Score = 37.4 bits (85), Expect = 0.12
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 13/94 (13%)
Query: 1407 PDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN-TCLCPNGFFGEHCQ---NAFCHPPC 1462
P C +P G C T+ +P + +P +C CP G G +CQ + PC
Sbjct: 45 PGPCAAQPCRNGGVC-TSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC 103
Query: 1463 KNGGHCMRNN-------VCVCREGYTGRRFQKSI 1489
+ G+C ++ +C+C EGY G ++++
Sbjct: 104 HH-GNCSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 35.8 bits (81), Expect = 0.34
Identities = 25/91 (27%), Positives = 35/91 (38%), Gaps = 26/91 (28%)
Query: 1520 PICLQKCKNGGECI----------APS-----ICHCPSSWEGVRCQI---PICNPKCLYG 1561
P Q C+NGG C AP+ C CP+ G CQ+ P + C +
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HH 105
Query: 1562 GRCIFPN-------VCSCRTEYSGVKCEKKI 1585
G C + +C C Y G CE+ +
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 33.5 bits (75), Expect = 1.7
Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 30/101 (29%)
Query: 1461 PCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPS-TCSCPSGWSGKRCN- 1518
PC+NGG VC R +P + P +C+CP+G SG C
Sbjct: 52 PCRNGG------VCTSRP------------EPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Query: 1519 --TPICLQKCKNGGECIAPS-------ICHCPSSWEGVRCQ 1550
P C + G C + S +C C +EG C+
Sbjct: 94 VADPCASNPCHH-GNCSSSSSSSSDGYLCICNEGYEGPNCE 133
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 139 bits (349), Expect = 3e-32
Identities = 94/273 (34%), Positives = 114/273 (41%), Gaps = 41/273 (15%)
Query: 1314 CKCKPGYIGSNCQ--TALC-DPDCKNHGKCIKPNICQCLPGHGGATCDEEHC-NPPCQHG 1369
C C G+ G+ C T C D C NHG CI C C PG+ G +C+E C +P C
Sbjct: 612 CLCHSGWKGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEVDCMDPTCSGR 670
Query: 1370 GTCLAGNLCTCPYGFVGPRCET--MVCNRHCENGGQCLTPD--ICQCKPGWYGPTCSTAL 1425
G C+ G C C G+ G CET C C G L PD +C C P W G CS +
Sbjct: 671 GVCVRGE-CHCSVGWGGTNCETPRATCLDQCSGHGTFL-PDTGLCSCDPSWTGHDCSIEI 728
Query: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGR-- 1483
C C G C TC C +G+ G C CHP C G C R+ C C G+ G
Sbjct: 729 CAADCGGHGVC-VGGTCRCEDGWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHC 786
Query: 1484 -------RFQKSICDPTCMNGGKC---VGPSTCSCPSGWSGKRCNTPI---CLQKCKNGG 1530
R K C C G+C + C C GW G C+T + C N G
Sbjct: 787 TIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDG 846
Query: 1531 ----ECIAPSICHCPSSWEGVRCQIPICNPKCL 1559
+C+ P C P C I NP CL
Sbjct: 847 DGLVDCMDPDCCLQP------LCHI---NPLCL 870
Score = 129 bits (323), Expect = 3e-29
Identities = 76/230 (33%), Positives = 100/230 (43%), Gaps = 15/230 (6%)
Query: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
++C C G C++G C C GF+GP C C C GQ + C C GW G
Sbjct: 564 DNCPSNCYGNGDCISGT-CHCFLGFLGPDCGRASCPVLCSGNGQYMKGR-CLCHSGWKGA 621
Query: 1420 TCS--TALC-DPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475
C T C D C N G+C TC+C G+ GE C+ C P C G C+R C
Sbjct: 622 ECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGE-CH 679
Query: 1476 CREGYTGRRFQ--KSICDPTCMNGGKCVGPST--CSCPSGWSGKRCNTPICLQKCKNGGE 1531
C G+ G + ++ C C G + P T CSC W+G C+ IC C G
Sbjct: 680 CSVGWGGTNCETPRATCLDQCSGHGTFL-PDTGLCSCDPSWTGHDCSIEICAADCGGHGV 738
Query: 1532 CIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
C+ + C C W G C C+P+C G C C C ++G C
Sbjct: 739 CVGGT-CRCEDGWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHC 786
Score = 99.8 bits (247), Expect = 2e-20
Identities = 92/332 (27%), Positives = 125/332 (37%), Gaps = 64/332 (19%)
Query: 1163 NDDCDAETRVTIEVTVKSCD-----CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEV 1217
ND ++E + ++S D C G C+S C C GF G C
Sbjct: 545 NDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGT----------CHCFLGFLGPDC-- 592
Query: 1218 DISGCQSNPCGLGSYI-------SGFHSYSCDCPPELKVETQFVNQFT--TQTVVLTRSD 1268
+ C G G Y+ SG+ CD P ++ N T T T +
Sbjct: 593 GRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGY 652
Query: 1269 KSVNKEEDD---KNAQGRKRHVKP----TSGNAFTICKYP--------CGKSRECVAPNI 1313
K + EE D GR V+ + G T C+ P G +
Sbjct: 653 KGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGL 712
Query: 1314 CKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCL 1373
C C P + G +C +C DC HG C+ C+C G GA CD+ C+P C GTC
Sbjct: 713 CSCDPSWTGHDCSIEICAADCGGHGVCV-GGTCRCEDGWMGAACDQRACHPRCAEHGTCR 771
Query: 1374 AGNLCTCPYGFVGPRC------ETMV---CNRHCENGGQCLTPDI----CQCKPGWYGPT 1420
G C C G+ G C + +V C C G+C T D+ C C+ GW G
Sbjct: 772 DGK-CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRC-TLDLNGWHCVCQLGWRGAG 829
Query: 1421 CSTAL---CDPVCLNGG----SCNKPNTCLCP 1445
C T++ C N G C P+ CL P
Sbjct: 830 CDTSMETACGDSKDNDGDGLVDCMDPDCCLQP 861
Score = 84.7 bits (208), Expect = 6e-16
Identities = 51/167 (30%), Positives = 66/167 (39%), Gaps = 11/167 (6%)
Query: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRF 1485
C C G C TC C GF G C A C C G M+ C+C G+ G
Sbjct: 566 CPSNCYGNGDCIS-GTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGR-CLCHSGWKGAEC 623
Query: 1486 Q---KSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQK-CKNGGECIAPSICHCP 1541
D C N G C+ TC C G+ G+ C C+ C G C+ CHC
Sbjct: 624 DVPTNQCIDVACSNHGTCI-TGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGE-CHCS 681
Query: 1542 SSWEGVRCQIP--ICNPKCLYGGRCI-FPNVCSCRTEYSGVKCEKKI 1585
W G C+ P C +C G + +CSC ++G C +I
Sbjct: 682 VGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEI 728
Score = 35.4 bits (80), Expect = 0.44
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 890 CPNLCSGNGQCMEWGCACSPSFSSYDCSDSYDKAPEITELGNAGFC 935
CP LCSGNGQ M+ C C + +C ++ ++ N G C
Sbjct: 597 CPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVA-CSNHGTC 641
Score = 34.3 bits (77), Expect = 0.99
Identities = 15/33 (45%), Positives = 17/33 (51%)
Query: 884 ILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
I SV CP+ C GNG C+ C C F DC
Sbjct: 560 IESVDNCPSNCYGNGDCISGTCHCFLGFLGPDC 592
Score = 34.3 bits (77), Expect = 0.99
Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 4/38 (10%)
Query: 890 CPNLCSGNGQCM----EWGCACSPSFSSYDCSDSYDKA 923
CP LC+GNG+C W C C + C S + A
Sbjct: 800 CPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETA 837
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 138 bits (348), Expect = 4e-32
Identities = 77/217 (35%), Positives = 103/217 (47%), Gaps = 30/217 (13%)
Query: 1330 CDPDCKNHGKCI---KPNI-CQCLPGHGGATCDEEHCNPPCQHGGTCLAGNL----CTCP 1381
C C+N G+CI K ++ C C P + G C+ HC+ CQ+GGTC+ L C+C
Sbjct: 4217 CKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNHCSNYCQNGGTCVPSVLGRPTCSCA 4276
Query: 1382 YGFVGPRCETMVCNRHCENGGQCL----TPDICQCKPGWYGPTCSTALCDPVCLNGGSCN 1437
GF GP C VC C+NGG C+ C C+P + G C +C C+N SC
Sbjct: 4277 LGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCT 4336
Query: 1438 KPN----TCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNN-----VCVCREGYTGRRFQKS 1488
+ C+CP + G C+ C C +GGHC+ N C C G Q
Sbjct: 4337 IGDDGSVECVCPTRYEGPKCEVDKC-VRC-HGGHCIINKDSEDIFCNCTNGKIASSCQ-- 4392
Query: 1489 ICDPTCMNGGKC-VGPST----CSCPSGWSGKRCNTP 1520
+CD C NGG C + P T C C + WSG +C P
Sbjct: 4393 LCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCERP 4429
Score = 127 bits (318), Expect = 1e-28
Identities = 79/244 (32%), Positives = 111/244 (45%), Gaps = 39/244 (15%)
Query: 1374 AGNLCTCPYG--FVGPRC--ETMV---CNRHCENGGQCLTPDI----CQCKPGWYGPTCS 1422
+G C CP G + C ++++ C CENGG+C+ + C C P + G C
Sbjct: 4190 SGATCVCPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCE 4249
Query: 1423 TALCDPVCLNGGSC-----NKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCM----RNNV 1473
C C NGG+C +P TC C GF G +C C C+NGG C+
Sbjct: 4250 VNHCSNYCQNGGTCVPSVLGRP-TCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPY 4308
Query: 1474 CVCREGYTGRRFQKSICDPTCMNGGKCV----GPSTCSCPSGWSGKRCNTPICLQKCKNG 1529
C C+ YTG R Q +C C+N C G C CP+ + G +C C+ +C +G
Sbjct: 4309 CHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCV-RC-HG 4366
Query: 1530 GECIAPS-----ICHCPSSWEGVRCQIPICNPKCLYGGRC-IFPN----VCSCRTEYSGV 1579
G CI C+C + CQ+ C+ C GG C + P VC C T +SG
Sbjct: 4367 GHCIINKDSEDIFCNCTNGKIASSCQL--CDGYCYNGGTCQLDPETNVPVCLCSTNWSGT 4424
Query: 1580 KCEK 1583
+CE+
Sbjct: 4425 QCER 4428
Score = 118 bits (296), Expect = 4e-26
Identities = 90/309 (29%), Positives = 132/309 (42%), Gaps = 57/309 (18%)
Query: 1289 PTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSN---------CQTALCDPDCKNHGK 1339
P +G F + K+ G S E +A NI K K I C C+ C
Sbjct: 4133 PKNG-VFRVQKFGHG-SVEYLALNIDKTKGVLISHRYKQLDLPNPCLDLACEFLC----- 4185
Query: 1340 CIKPNICQCLPGHG----GATCDEEH-----CNPPCQHGGTCLA---GNL-CTCPYGFVG 1386
+ P+ C+ G TC+++ C C++GG C+ G+L C C + G
Sbjct: 4186 LLNPSGATCVCPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSG 4245
Query: 1387 PRCETMVCNRHCENGGQCLTPDI----CQCKPGWYGPTCSTALCDPVCLNGGSC-----N 1437
RCE C+ +C+NGG C+ + C C G+ GP C +C+ C NGG+C N
Sbjct: 4246 ERCEVNHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGN 4305
Query: 1438 KPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNN----VCVCREGYTGRRFQKSICDPT 1493
+P C C + G+ CQ CH C N C + CVC Y G + + C
Sbjct: 4306 QPY-CHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKC--V 4362
Query: 1494 CMNGGKCVGPST-----CSCPSGWSGKRCNTPICLQKCKNGGEC-IAPS----ICHCPSS 1543
+GG C+ C+C +G C +C C NGG C + P +C C ++
Sbjct: 4363 RCHGGHCIINKDSEDIFCNCTNGKIASSCQ--LCDGYCYNGGTCQLDPETNVPVCLCSTN 4420
Query: 1544 WEGVRCQIP 1552
W G +C+ P
Sbjct: 4421 WSGTQCERP 4429
Score = 112 bits (280), Expect = 3e-24
Identities = 64/193 (33%), Positives = 86/193 (44%), Gaps = 26/193 (13%)
Query: 1421 CSTALCDPVCLNGGSCNKPNTCLCPNGFF-------GEHCQNAFCHPPCKNGGHCMRNNV 1473
C C+ +CL S TC+CP G + + + C C+NGG C+ N
Sbjct: 4176 CLDLACEFLCLLNPS---GATCVCPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEK 4232
Query: 1474 ----CVCREGYTGRRFQKSICDPTCMNGGKCV----GPSTCSCPSGWSGKRCNTPICLQK 1525
C C Y+G R + + C C NGG CV G TCSC G++G C +C
Sbjct: 4233 GDLRCHCWPSYSGERCEVNHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDF 4292
Query: 1526 CKNGGECIAPS----ICHCPSSWEGVRCQIPICNPKCLYGGRCIFPN----VCSCRTEYS 1577
C+NGG CI + CHC + G RCQ +C+ C+ C + C C T Y
Sbjct: 4293 CQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYE 4352
Query: 1578 GVKCEKKIQIRRH 1590
G KCE +R H
Sbjct: 4353 GPKCEVDKCVRCH 4365
Score = 36.2 bits (82), Expect = 0.26
Identities = 50/203 (24%), Positives = 72/203 (35%), Gaps = 55/203 (27%)
Query: 1322 GSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC----DEEHCNPP---CQHGG--TC 1372
G N C PD G C+ P++ +C G C DE+ CN C H +C
Sbjct: 1052 GCNGNEFQCHPD----GNCV-PDLWRC---DGEKDCEDGSDEKGCNGTIRLCDHKTKFSC 1103
Query: 1373 LAGNLCT-----------CPYGFVGPRCETMVCN--RH-CENGGQ-CLTPD-ICQCKPGW 1416
+ C C C++ +C +H C N CL P+ +C K
Sbjct: 1104 WSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKLCNGKKDC 1163
Query: 1417 YGPTCSTALCDPVCLNGGSCN--------KPNTCLCPNGF----------FGEHCQNAF- 1457
+ LCD LN G C+ + C CP G ++C N
Sbjct: 1164 PDGSDEGYLCDECSLNNGGCSNHCSVVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSNHLK 1223
Query: 1458 CHPPCKNGGHCMRNNVCVCREGY 1480
C C+ H ++ C C EG+
Sbjct: 1224 CSQVCEQHKHTVK---CSCYEGW 1243
Score = 31.2 bits (69), Expect = 8.4
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 6/49 (12%)
Query: 1170 TRVTIEVTVKSCD--CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCE 1216
T I + + CD C NGG+C D P + V +C+C + G+ CE
Sbjct: 4383 TNGKIASSCQLCDGYCYNGGTCQLD----PETNVPVCLCSTNWSGTQCE 4427
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 135 bits (341), Expect = 2e-31
Identities = 109/381 (28%), Positives = 147/381 (38%), Gaps = 102/381 (26%)
Query: 1297 ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCD-----PDCKNHGKCIKPNICQ---- 1347
+C C R CV+P+ C C+PG+ G +C + CD P C N +C +C
Sbjct: 102 LCTEECVHGR-CVSPDTCHCEPGWGGPDCSSG-CDSDHWGPHCSNRCQCQNGALCNPITG 159
Query: 1348 ---CLPGHGGATCDE--------EHCNPPCQ--HGGTC--LAGNLCTCPYGFVGPRCETM 1392
C G G C+E + C PCQ HG +C AG C C G+ G CE +
Sbjct: 160 ACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGE-CLCAPGYTGVYCEEL 218
Query: 1393 V--------CNRH--CENGGQC--LTPDICQCKPGWYGPTCSTALCDP-----------V 1429
C C+NGG C +T + C C PGW G C+ C P
Sbjct: 219 CPPGSHGAHCELRCPCQNGGTCHHITGE-CACPPGWTGAVCAQP-CPPGTFGQNCSQDCP 276
Query: 1430 CLNGGSCNK-PNTCLCPNGFFGEHCQ----------NAFCHPPCKNGGHCM-RNNVCVCR 1477
C +GG C+ C C G+ G+ CQ H C NGG C C C
Sbjct: 277 CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECE 336
Query: 1478 EGYTGRRFQKSICDPTCMNGGKCVGP---------------STCSCPSGWSGKRCNTPIC 1522
GY G R Q+ +C P ++G C P C+C GWSG CN
Sbjct: 337 PGYKGPRCQERLC-PEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCP 395
Query: 1523 LQ----------KCKNGGECIA-PSICHCPSSWEGVRCQI--------PICNP--KCLYG 1561
+ C+NG +C + C C + G C + P C+ C G
Sbjct: 396 VGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG 455
Query: 1562 GRCI-FPNVCSCRTEYSGVKC 1581
G C C+C+ + G+ C
Sbjct: 456 GTCSPVDGSCTCKEGWQGLDC 476
Score = 132 bits (333), Expect = 2e-30
Identities = 102/325 (31%), Positives = 132/325 (40%), Gaps = 67/325 (20%)
Query: 1315 KCKPGYI--GSNCQTALCDPDCKNHGKCIKPNICQCLPGHGG----ATCDEEHCNPPCQH 1368
+C PGY G C LC +C HG+C+ P+ C C PG GG + CD +H P C +
Sbjct: 87 QCCPGYYESGDFC-IPLCTEECV-HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSN 144
Query: 1369 GGTCLAGNL-------CTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPG-WYGPT 1420
C G L C C GF G RCE + +G C P CQC+ G P
Sbjct: 145 RCQCQNGALCNPITGACVCAAGFRGWRCEELCAPG--THGKGCQLP--CQCRHGASCDPR 200
Query: 1421 CSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR-NNVCVCREG 1479
LC P G C + LCP G G HC+ PC+NGG C C C G
Sbjct: 201 AGECLCAP-GYTGVYCEE----LCPPGSHGAHCE---LRCPCQNGGTCHHITGECACPPG 252
Query: 1480 YTGRRF----------QKSICDPTCMNGGKCVG-PSTCSCPSGWSGKRCNTPI------- 1521
+TG Q D C +GG+C C C +G+ G RC
Sbjct: 253 WTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGF 312
Query: 1522 -CLQ--KCKNGGECI-APSICHCPSSWEGVRCQIPICNPKCLYGGRCIFP---------- 1567
C Q C NGG+C C C ++G RCQ +C P+ L+G C P
Sbjct: 313 QCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLC-PEGLHGPGCTLPCPCDADNTIS 371
Query: 1568 -----NVCSCRTEYSGVKCEKKIQI 1587
C+C+ +SG C + +
Sbjct: 372 CHPVTGACTCQPGWSGHHCNESCPV 396
Score = 126 bits (316), Expect = 2e-28
Identities = 131/509 (25%), Positives = 175/509 (34%), Gaps = 149/509 (29%)
Query: 1181 CDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYS 1240
CDC NGG C SP +G C C PG+ G C Q C G + G +
Sbjct: 318 CDCHNGGQC------SPTTGA--CECEPGYKGPRC-------QERLCPEGLHGPGC-TLP 361
Query: 1241 CDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKY 1300
C C + + V T G + G C+
Sbjct: 362 CPCDADNTISCHPVTGACTC----------------QPGWSGHHCNESCPVGYYGDGCQL 405
Query: 1301 PCGKSRECVAPNI---CKCKPGYIGS----NCQTALCDPDCKNHGKCIKPNICQCLPGHG 1353
PC +I C C PG++G +C P+C + C C P G
Sbjct: 406 PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCS--PVDG 463
Query: 1354 GATCDEE----HCNPPCQHGG---------TCLAG-------NLCTCPYGFVGPRCET-- 1391
TC E C PC G TC G C+C G++G CE
Sbjct: 464 SCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPC 523
Query: 1392 ------MVCNRHCE----NGGQCLTPDIC------------QCKPGWYGPTCSTALCDPV 1429
+ C+ HC+ +G +T C C PG +GP CS +
Sbjct: 524 PDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCS--- 580
Query: 1430 CLNGGSCN-KPNTCLCPNGFFGEHCQNAF--------CHPPCKNGGHCMR-----NNVCV 1475
C NGGSC+ + +C C GF G CQ C PC H R + +C
Sbjct: 581 CENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE 640
Query: 1476 CREGYTGRRFQKSICDPTCMNGG---------KCVGPSTCS-------CPSGWSGKRCNT 1519
C G++G ++C+ C G C TCS C GW GK C+
Sbjct: 641 CLPGFSG-----ALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ 695
Query: 1520 --------PICLQKCK--NGGECIAPS-ICHCPSSWEGVRC--QIP----------ICNP 1556
P C C NG C A CHC W G+ C + P +C
Sbjct: 696 ACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVC-- 753
Query: 1557 KCLYGGRCI-FPNVCSCRTEYSGVKCEKK 1584
+C G C C+CRT ++G CE++
Sbjct: 754 QCQNGASCDHISGKCTCRTGFTGQHCEQR 782
Score = 122 bits (305), Expect = 4e-27
Identities = 133/508 (26%), Positives = 184/508 (36%), Gaps = 149/508 (29%)
Query: 1181 CDCLNGGSC---VSDRNFSPG-SGVYLC--VCLPGFHGSLCEVDISGCQSNPCGLGSYIS 1234
C C +G SC + +PG +GVY C +C PG HG+ CE+ C G +I+
Sbjct: 189 CQCRHGASCDPRAGECLCAPGYTGVY-CEELCPPGSHGAHCEL---RCPCQNGGTCHHIT 244
Query: 1235 GFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKP----T 1290
G C CPP + Q ++ +++ + G+ HV T
Sbjct: 245 G----ECACPP------GWTGAVCAQPCPPGTFGQNCSQDCPCHHG-GQCDHVTGQCHCT 293
Query: 1291 SGNAFTICK---------YPCGKSREC-------VAPNICKCKPGYIGSNCQTALC---- 1330
+G C+ + C + +C C+C+PGY G CQ LC
Sbjct: 294 AGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGL 353
Query: 1331 -DPDCKNHGKCIKPNICQCLPGHGGATCDE----EHCNP---------------PCQHGG 1370
P C C N C P G TC HCN CQ+G
Sbjct: 354 HGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGA 413
Query: 1371 TC--LAGNLCTCPYGFVGPRCE------------TMVCNRHCENGGQCLTPD-ICQCKPG 1415
C + G CTC GF+G C + +C+ C NGG C D C CK G
Sbjct: 414 DCHSITGG-CTCAPGFMGEVCAVSCAAGTYGPNCSSICS--CNNGGTCSPVDGSCTCKEG 470
Query: 1416 WYGPTCSTAL--------CDP--VCLNGGSCNK-PNTCLCPNGFFGEHCQNAFCHPPCKN 1464
W G C+ C+ C NG +C+ +C C G+ G+ C+ PC +
Sbjct: 471 WQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCE-----LPCPD 525
Query: 1465 GG---HCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNT-- 1519
G +C + C +G CDP C C +GW+G RC++
Sbjct: 526 GTFGLNCSEHCDCSHADG----------CDPV---------TGHCCCLAGWTGIRCDSTC 566
Query: 1520 ------PICLQ--KCKNGGECI-APSICHCPSSWEGVRCQIPICNPKCLYGGRCIFP--- 1567
P C C+NGG C C C + G CQ IC P YG C P
Sbjct: 567 PPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RIC-PPGFYGHGCAQPCPL 624
Query: 1568 ------------NVCSCRTEYSGVKCEK 1583
+C C +SG C +
Sbjct: 625 CVHSSRPCHHISGICECLPGFSGALCNQ 652
Score = 112 bits (280), Expect = 3e-24
Identities = 115/414 (27%), Positives = 150/414 (36%), Gaps = 117/414 (28%)
Query: 1179 KSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFH- 1237
+SC C NG +C SP G C C PG+ G CE+ PC G++ G +
Sbjct: 491 ESCTCANGAAC------SPIDGS--CSCTPGWLGDTCEL--------PCPDGTF--GLNC 532
Query: 1238 SYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTI 1297
S CDC + T L D GR N
Sbjct: 533 SEHCDCS-----HADGCDPVTGHCCCLAGW---TGIRCDSTCPPGR------WGPNCSVS 578
Query: 1298 CKYPCGKSRECVAPN-ICKCKPGYIGSNCQTALCDPDCKNHGKCIKP------------- 1343
C C C + C+C PG+ G CQ +C P HG C +P
Sbjct: 579 CS--CENGGSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHG-CAQPCPLCVHSSRPCHH 634
Query: 1344 --NICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENG 1401
IC+CLPG GA C++ C G+ G C +C+ C N
Sbjct: 635 ISGICECLPGFSGALCNQ-------------------VCAGGYFGQDC-AQLCS--CANN 672
Query: 1402 GQCLTPD-ICQCKPGWYGPTCSTALCDP-----------VCLNGGSCNKPN--------- 1440
G C D CQC PGW G CS A C P C NG SC+ +
Sbjct: 673 GTCSPIDGSCQCFPGWIGKDCSQA-CPPGFWGPACFHACSCHNGASCSAEDGACHCTPGW 731
Query: 1441 -----TCLCPNGFFGEHCQNAFCHPPCKNGGHCMR-NNVCVCREGYTGRRFQKSICDPT- 1493
T CP FFG+ C C C+NG C + C CR G+TG+ ++ T
Sbjct: 732 TGLFCTQRCPAAFFGKDC-GRVCQ--CQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTF 788
Query: 1494 ---------CMNGGKCVG-PSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSI 1537
CMN C TC C G+ G RC+ + + N I+P++
Sbjct: 789 GYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISPAL 842
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 131 bits (330), Expect = 5e-30
Identities = 55/121 (45%), Positives = 68/121 (56%), Gaps = 12/121 (9%)
Query: 1429 VCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKS 1488
VCL G+ P C A C PC+NGG C R N C C EG+ GR ++
Sbjct: 3455 VCLENGTWTSPPIC------------RAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEP 3502
Query: 1489 ICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVR 1548
IC C+NGG+CV P C CP GW+G RC+T +C C NGG+C+ P+ CHC SSW G
Sbjct: 3503 ICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHN 3562
Query: 1549 C 1549
C
Sbjct: 3563 C 3563
Score = 125 bits (314), Expect = 3e-28
Identities = 48/113 (42%), Positives = 65/113 (57%)
Query: 1472 NVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGE 1531
+VC+ +T +++C C NGG C P+ CSCP GW G+ C PIC+ C NGG
Sbjct: 3454 SVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGR 3513
Query: 1532 CIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKK 1584
C+AP C CP W G RC +C CL GG+C+ PN C C + ++G C +K
Sbjct: 3514 CVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRK 3566
Score = 115 bits (288), Expect = 3e-25
Identities = 46/110 (41%), Positives = 59/110 (53%)
Query: 1409 ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHC 1468
+C W P A+C C NGG C +PN C CP G+ G C+ C PC NGG C
Sbjct: 3455 VCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRC 3514
Query: 1469 MRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCN 1518
+ C C G+TG R ++C C+NGGKCV P+ C C S W+G C+
Sbjct: 3515 VAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCS 3564
Score = 114 bits (286), Expect = 6e-25
Identities = 49/120 (40%), Positives = 64/120 (53%), Gaps = 12/120 (10%)
Query: 1334 CKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMV 1393
C +G P IC+ + C PCQ+GG C N C+CP G++G CE +
Sbjct: 3456 CLENGTWTSPPICRAV------------CRFPCQNGGICQRPNACSCPEGWMGRLCEEPI 3503
Query: 1394 CNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHC 1453
C C NGG+C+ P C C PGW G C TA+C CLNGG C +PN C C + + G +C
Sbjct: 3504 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3563
Score = 112 bits (281), Expect = 2e-24
Identities = 82/237 (34%), Positives = 109/237 (45%), Gaps = 38/237 (16%)
Query: 1283 RKRHVKPTSGNAFTICKY-PCGKSRECVAPN---ICKCKPGYIGSNCQTAL--CDP-DCK 1335
+KRH S F C + PC S C +C C GY G C+T + C P C
Sbjct: 1184 KKRH--EISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCL 1241
Query: 1336 NHGKC---IKPNICQCLPGHGGATCDE---EHCNPPCQHGGTCL---AGNLCTCPYGFVG 1386
N+G C + IC+C G+ G C+E E + PC + G C+ AG CTC GFVG
Sbjct: 1242 NNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVG 1301
Query: 1387 PRCETMV--CNRH-CENGGQC---LTPDICQCKPGWYGPTC----STALCDPVCLNGGSC 1436
CET V C + C N C + +C+C PG+ G C L P C NG +C
Sbjct: 1302 LHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP-CKNGATC 1360
Query: 1437 N---KPNTCLCPNGFFGEHCQ---NAFCHPPCKNGGHC---MRNNVCVCREGYTGRR 1484
CLC GF G HC+ N PC+N C + + C C+ G++G+R
Sbjct: 1361 KDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKR 1417
Score = 104 bits (259), Expect = 8e-22
Identities = 48/111 (43%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 1372 CLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCL 1431
CL T P P C VC C+NGG C P+ C C GW G C +C CL
Sbjct: 3456 CLENGTWTSP-----PICRA-VCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCL 3509
Query: 1432 NGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTG 1482
NGG C P C CP G+ G C A C PC NGG C+R N C C +TG
Sbjct: 3510 NGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTG 3560
Score = 102 bits (253), Expect = 4e-21
Identities = 43/95 (45%), Positives = 53/95 (55%)
Query: 1328 ALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGP 1387
A+C C+N G C +PN C C G G C+E C PC +GG C+A C CP G+ G
Sbjct: 3470 AVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGS 3529
Query: 1388 RCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCS 1422
RC T VC C NGG+C+ P+ C C W G CS
Sbjct: 3530 RCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCS 3564
Score = 97.8 bits (242), Expect = 7e-20
Identities = 101/362 (27%), Positives = 137/362 (37%), Gaps = 74/362 (20%)
Query: 1222 CQSNPCGLGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQ 1281
C+S C LG+Y F S SC PE N T + + S V E +
Sbjct: 1069 CES--CPLGTYQPKFGSRSCLSCPE--------NTSTVKRGAVNISACGVPCPEGKFSRS 1118
Query: 1282 G-------RKRHVKPTSGNAFTICKYPCGKSRECVAPNICKC------------------ 1316
G + + +P +G AF + G + + +I +C
Sbjct: 1119 GLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPA 1178
Query: 1317 ------KPGYIGSNCQTALCDPDCKNHGKCI---KPNICQCLPGHGGATC--DEEHCNP- 1364
K I S C N G C + +C C G+ G C D + C+P
Sbjct: 1179 SLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPL 1238
Query: 1365 PCQHGGTC--LAGN-LCTCPYGFVGPRCETMV---CNRHCENGGQCLTPDI---CQCKPG 1415
PC + G C L G +C CP G+ G RCE + + C N G C+ C C G
Sbjct: 1239 PCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKG 1298
Query: 1416 WYGPTCSTALCD---PVCLNGGSCNKP---NTCLCPNGFFGEHC---QNAFCHPPCKNGG 1466
+ G C T + + CLN C C CP GF G C + PCKNG
Sbjct: 1299 FVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGA 1358
Query: 1467 HC---MRNNVCVCREGYTGRRFQKSI--CDPT-CMNGGKCV---GPSTCSCPSGWSGKRC 1517
C + C+C G+TG + +I C C N CV +C C G+SGKRC
Sbjct: 1359 TCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Query: 1518 NT 1519
T
Sbjct: 1419 ET 1420
Score = 94.4 bits (233), Expect = 8e-19
Identities = 72/219 (32%), Positives = 95/219 (43%), Gaps = 35/219 (15%)
Query: 1398 CENGGQCLTPD---ICQCKPGWYGPTCSTAL--CDPV-CLNGGSCNK---PNTCLCPNGF 1448
C N G C +C C G+ G C T + C P+ CLN G C C CP+G+
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 1449 FGEHCQ---NAFCHPPCKNGGHCMRNNV---CVCREGYTGRRFQKSI--CDPT-CMNGGK 1499
G+ C+ N PC N G C+ C C +G+ G + + C C+N
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV 1321
Query: 1500 C---VGPSTCSCPSGWSGKRC--NTPICL-QKCKNGGECI--APSI-CHCPSSWEGVRCQ 1550
C VG C CP G+ G RC N CL Q CKNG C A S C C + + G C+
Sbjct: 1322 CEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCE 1381
Query: 1551 IPI----CNPKCLYGGRCIFP---NVCSCRTEYSGVKCE 1582
+ I NP C C+ C C+ +SG +CE
Sbjct: 1382 LNINECQSNP-CRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 89.0 bits (219), Expect = 3e-17
Identities = 34/93 (36%), Positives = 47/93 (50%)
Query: 1297 ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGAT 1356
+C++PC C PN C C G++G C+ +C C N G+C+ P C C PG G+
Sbjct: 3471 VCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSR 3530
Query: 1357 CDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRC 1389
C C PC +GG C+ N C C + G C
Sbjct: 3531 CHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3563
Score = 85.9 bits (211), Expect = 3e-16
Identities = 74/265 (27%), Positives = 108/265 (40%), Gaps = 70/265 (26%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPC---GLGSYISGFHSY 1239
C N G+C G G Y+C+C G+ G CE DI C PC G+ + G +
Sbjct: 1202 CHNSGTCQQ-----LGRG-YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVG--EF 1253
Query: 1240 SCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICK 1299
C+CP + +T Q R ++++N+
Sbjct: 1254 ICECP----------SGYTGQ-----RCEENINE-----------------------CSS 1275
Query: 1300 YPCGKSREC---VAPNICKCKPGYIGSNCQTAL--CDPD-CKNHGKC---IKPNICQCLP 1350
PC C VA C C G++G +C+T + C + C N+ C + +C+C P
Sbjct: 1276 SPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPP 1335
Query: 1351 GHGGATCD---EEHCNPPCQHGGTCLAGN---LCTCPYGFVGPRCETMV--CNRH-CENG 1401
G G C +E + PC++G TC G C C GF G CE + C + C N
Sbjct: 1336 GFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQ 1395
Query: 1402 GQC---LTPDICQCKPGWYGPTCST 1423
C L C+C+PG+ G C T
Sbjct: 1396 ATCVDELNSYSCKCQPGFSGKRCET 1420
Score = 79.3 bits (194), Expect = 3e-14
Identities = 83/353 (23%), Positives = 114/353 (32%), Gaps = 97/353 (27%)
Query: 1303 GKSRECVAPNICKC----KPGYIGSNCQTALCD-PDCKNHGKCIKPN-------ICQCLP 1350
G + E V ++C+ +P + +C C P+ HG + I QC P
Sbjct: 3210 GYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEP 3269
Query: 1351 GH------------------GGATCDEEHCNPPCQH-GGTCLAGNLCTCP---------Y 1382
G+ G A C E C P + G N T P Y
Sbjct: 3270 GYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGY 3329
Query: 1383 GFVGPRCETMVCNRHCENGGQCLTPDICQCKPG-------------------WYGPTCST 1423
GP HC G P + CKP + S
Sbjct: 3330 SLEGPS------EAHCTENGTWSHP-VPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSI 3382
Query: 1424 ALCDPVCLNGG---SCNKPNTCLCPNGFFGEHCQNAFCHPPCK------NGGHCMRNNVC 1474
+ L G +CN T + C+ C PP G H ++
Sbjct: 3383 KCREGFLLQGHGIITCNPDETWTQTSA----KCEKISCGPPAHVENAIARGVHYQYGDMI 3438
Query: 1475 V--CREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGEC 1532
C GY F +S+C + G P C +C C+NGG C
Sbjct: 3439 TYSCYSGYMLEGFLRSVC----LENGTWTSPPICRA------------VCRFPCQNGGIC 3482
Query: 1533 IAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKI 1585
P+ C CP W G C+ PIC CL GGRC+ P C C ++G +C +
Sbjct: 3483 QRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAV 3535
Score = 75.5 bits (184), Expect = 4e-13
Identities = 50/147 (34%), Positives = 67/147 (45%), Gaps = 23/147 (15%)
Query: 1461 PCKNGGHCM---RNNVCVCREGYTGRRFQKSI--CDPT-CMNGGKC---VGPSTCSCPSG 1511
PC N G C R VC+C GYTG + + I C P C+N G C VG C CPSG
Sbjct: 1201 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSG 1260
Query: 1512 WSGKRCNTPI---CLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI----CNPKCLYG 1561
++G+RC I C N G C +A C C + G+ C+ + NP CL
Sbjct: 1261 YTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP-CLNN 1319
Query: 1562 GRC---IFPNVCSCRTEYSGVKCEKKI 1585
C + +C C + G +C K +
Sbjct: 1320 AVCEDQVGGFLCKCPPGFLGTRCGKNV 1346
Score = 74.3 bits (181), Expect = 9e-13
Identities = 30/64 (46%), Positives = 35/64 (54%)
Query: 1297 ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGAT 1356
IC PC CVAP C C PG+ GS C TA+C C N GKC++PN C CL G
Sbjct: 3503 ICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHN 3562
Query: 1357 CDEE 1360
C +
Sbjct: 3563 CSRK 3566
Score = 40.4 bits (93), Expect = 0.014
Identities = 36/143 (25%), Positives = 42/143 (29%), Gaps = 55/143 (38%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCD 1242
C NGG C C C G+ G LCE I PC G Y CD
Sbjct: 3476 CQNGGICQRPN---------ACSCPEGWMGRLCEEPICIL---PCLNGGRCVA--PYQCD 3521
Query: 1243 CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPC 1302
CPP G + H +C+ PC
Sbjct: 3522 CPP---------------------------------GWTGSRCHT--------AVCQSPC 3540
Query: 1303 GKSRECVAPNICKCKPGYIGSNC 1325
+CV PN C C + G NC
Sbjct: 3541 LNGGKCVRPNRCHCLSSWTGHNC 3563
Score = 37.0 bits (84), Expect = 0.15
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 13/68 (19%)
Query: 1175 EVTVKSCD---CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGS 1231
E+ + C C N +CV + N Y C C PGF G CE + QS L
Sbjct: 1381 ELNINECQSNPCRNQATCVDELNS------YSCKCQPGFSGKRCETE----QSTGFNLDF 1430
Query: 1232 YISGFHSY 1239
+SG + Y
Sbjct: 1431 EVSGIYGY 1438
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 131 bits (329), Expect = 6e-30
Identities = 136/519 (26%), Positives = 176/519 (33%), Gaps = 126/519 (24%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDIS------GC-QSNPCGLG---SY 1232
C CV S C C GF G C+ + GC Q+ C +G
Sbjct: 650 CSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDS 709
Query: 1233 ISGFHSYSC-------DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKR 1285
+SG C DC E V T VN ++ + + G
Sbjct: 710 VSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC 769
Query: 1286 HVKPTSGNAFTICKYPCGKSRECVA----PNICKCKPGYIGSNCQTAL--------CDP- 1332
G C+ C + C C PG++GS CQ C
Sbjct: 770 EADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR 829
Query: 1333 -DCKNHGKCIKPN-ICQCLPGHGGATC----DEEHCNPPCQHGGTCLAGN--------LC 1378
C N G C C C PG G +C D H P C H C AG+ LC
Sbjct: 830 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLC 889
Query: 1379 TCPYGFVGPRCETMVCNRH----------CENGGQC-LTPDICQCKPGWYGPTCSTA--- 1424
C G+VGPRCE H C++G C C C GW G C A
Sbjct: 890 LCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
Query: 1425 ---------LCDPVCLNGGSCNKPN-TCLCPNGFFGEHC----------QNAFCHPPCKN 1464
C+ C G +C+ N +CLCP G G C N C N
Sbjct: 950 GFFGLDCRSACN--CTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFN 1007
Query: 1465 GGHC-MRNNVCVCREGYTGRRFQKSI--------CDPTCM--NGGKCVGPS-TCSCPSGW 1512
G C + C C G+ G ++ C +C+ NGG C S C+CP GW
Sbjct: 1008 GASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGW 1067
Query: 1513 SGKRCNTPICLQK-----CKNGGECIAPSICH-------CPSSWEGVRCQIPICNPKCLY 1560
+G C CL + C++ G C+ +C CP+ W G +CQ P CL
Sbjct: 1068 AGLACEKE-CLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSP-----CLR 1121
Query: 1561 G-------GRCIFP---------NVCSCRTEYSGVKCEK 1583
G RC P C C ++G CE+
Sbjct: 1122 GWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQ 1160
Score = 129 bits (325), Expect = 2e-29
Identities = 112/383 (29%), Positives = 147/383 (38%), Gaps = 109/383 (28%)
Query: 1302 CGKSREC-VAPNICKCKPGYIGSNCQTALCD-----PDCKN-------HGKCIK-PNICQ 1347
C C A C C PG+ G +CQ A CD PDC + HG C +C
Sbjct: 832 CANDGHCHPATGHCSCAPGWTGFSCQRA-CDTGHWGPDCSHPCNCSAGHGSCDAISGLCL 890
Query: 1348 CLPGHGGATCDEE----HCNP------PCQHGGTC-LAGNLCTCPYGFVGPRCE------ 1390
C G+ G C+++ H P CQHG C CTCP G+ G CE
Sbjct: 891 CEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG 950
Query: 1391 ------TMVCNRHCENGGQC-LTPDICQCKPGWYGPTCSTAL--------CDPVC--LNG 1433
CN C G C C C G GP C+ C C NG
Sbjct: 951 FFGLDCRSACN--CTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNG 1008
Query: 1434 GSCNKPN------------TCL--CPNGFFGEHCQNAFCHPPCKNGGHCMR-NNVCVCRE 1478
SC+ + +CL CP G +G++C+++ C+NGG C + C C E
Sbjct: 1009 ASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL---CQNGGTCDPVSGHCACPE 1065
Query: 1479 GYTGRRFQKSICDPT-----------CMNGGKCVGPST--CSCPSGWSGKRCNTPI---- 1521
G+ G +K C P C+NGG C P T C CP+GW+G +C +P
Sbjct: 1066 GWAGLACEKE-CLPRDVRAGCRHSGGCLNGGLC-DPHTGRCLCPAGWTGDKCQSPCLRGW 1123
Query: 1522 ----CLQKCK--NGGECI-APSICHCPSSWEGVRCQIPICNP-----KCLYGGRCIFPN- 1568
C Q+C G C C CP + G C+ C P C +C N
Sbjct: 1124 FGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE-QACPPGSFGEDCAQMCQCPGENP 1182
Query: 1569 -------VCSCRTEYSGVKCEKK 1584
CSC Y G C+++
Sbjct: 1183 ACHPATGTCSCAAGYHGPSCQQR 1205
Score = 112 bits (281), Expect = 2e-24
Identities = 132/473 (27%), Positives = 172/473 (36%), Gaps = 128/473 (27%)
Query: 1180 SCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDI------SGCQSNPCGLGSYI 1233
SC C NGG+C P SG C C G+ G CE + +GC+ + L +
Sbjct: 1045 SCLCQNGGTC------DPVSGH--CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGL 1096
Query: 1234 SGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
H+ C CP DK + ++ G
Sbjct: 1097 CDPHTGRCLCPAGWT------------------GDKC------------QSPCLRGWFGE 1126
Query: 1294 AFTI-CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDP-----DCKNHGKCIKPNICQ 1347
A C P G + V C+C PG+ GS C+ A C P DC +C N
Sbjct: 1127 ACAQRCSCPPGAACHHVT-GACRCPPGFTGSGCEQA-CPPGSFGEDCAQMCQCPGENPA- 1183
Query: 1348 CLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQC-LT 1406
C P G +C + P CQ CP G GP CE +C C NGG C
Sbjct: 1184 CHPATGTCSCAAGYHGPSCQQ----------RCPPGRYGPGCE-QLCG--CLNGGSCDAA 1230
Query: 1407 PDICQCKPGWYGPTCS------------TALCDPVCLNGGSCNK-PNTCLCPNGFFGEHC 1453
C+C G+ G C+ T +C C G +C+ TCLCP G G C
Sbjct: 1231 TGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAACDPVTGTCLCPPGRAGVRC 1288
Query: 1454 -----QNAF---CHP--PCKNGGHC-MRNNVCVCREGYTGRRFQKSICDP---------- 1492
QN F C C+NGG C N C C G+TGR + + C P
Sbjct: 1289 ERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELA-CPPGRYGAACHLE 1347
Query: 1493 -TCMNGGKC-VGPSTCSCPSGWSGKRCNTPI--------C--LQKCKNGGECIAPS-ICH 1539
+C N C TC C G+ G+ C P C L C++G C S C
Sbjct: 1348 CSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCL 1407
Query: 1540 CPSSWEGVRCQIPI--------CNPKC-LYGGRCIFP--NVCSCRTEYSGVKC 1581
CP+ + G C+ C+ +C GG P +C C SG C
Sbjct: 1408 CPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATC 1460
Score = 105 bits (262), Expect = 3e-22
Identities = 121/464 (26%), Positives = 155/464 (33%), Gaps = 146/464 (31%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCV-----------CLPGFHGSLCEVDISGCQSNPCGLGS 1231
CLNGG C P +G LC CL G+ G C C P
Sbjct: 1091 CLNGGLC------DPHTGRCLCPAGWTGDKCQSPCLRGWFGEACA---QRCSCPPGAACH 1141
Query: 1232 YISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTS 1291
+++G +C CPP G ++ P S
Sbjct: 1142 HVTG----ACRCPPGF-------------------------------TGSGCEQACPPGS 1166
Query: 1292 --GNAFTICKYPCGKSREC-VAPNICKCKPGYIGSNCQTALCDPD-----------CKNH 1337
+ +C+ P G++ C A C C GY G +CQ C P C N
Sbjct: 1167 FGEDCAQMCQCP-GENPACHPATGTCSCAAGYHGPSCQQR-CPPGRYGPGCEQLCGCLNG 1224
Query: 1338 GKC-IKPNICQCLPGHGGA----TCDEEHCNPPCQHGGTCLAG-------NLCTCPYGFV 1385
G C C+C G G TC + P C H C G C CP G
Sbjct: 1225 GSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRA 1284
Query: 1386 GPRCET--------MVCNR--HCENGGQCLTPD-ICQCKPGWYGPTCSTALCDP------ 1428
G RCE + C C NGG C + C C GW G C A C P
Sbjct: 1285 GVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELA-CPPGRYGAA 1343
Query: 1429 -----VCLNGGSCNKPN-TCLCPNGFFGEHCQNAFCHPP-----------CKNGGHCMR- 1470
C N +C TC C GF+G+ C++ C P C++G C
Sbjct: 1344 CHLECSCHNNSTCEPATGTCRCGPGFYGQACEHP-CPPGFHGAGCQGLCWCQHGAPCDPI 1402
Query: 1471 NNVCVCREGYTGRRFQKSICDP-----------TCMNGGKCVGPST--CSCPSGWSGKRC 1517
+ C+C G+ G ++ C+P C G C P T C CP G SG C
Sbjct: 1403 SGRCLCPAGFHGHFCERG-CEPGSFGEGCHQRCDCDGGAPC-DPVTGLCLCPPGRSGATC 1460
Query: 1518 NT--------PICLQKCKNGGECIAPSI---CHCPSSWEGVRCQ 1550
N P C C GG + CHC + G C+
Sbjct: 1461 NLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCR 1504
Score = 100 bits (250), Expect = 9e-21
Identities = 125/501 (24%), Positives = 166/501 (33%), Gaps = 157/501 (31%)
Query: 1182 DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSC 1241
DC NGG+C+ G+ C C G+ G +C C + G S+SC
Sbjct: 526 DCRNGGTCLL--------GLDGCDCPEGWTGLICN---ETCPPDTFGKNC------SFSC 568
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301
C N T +V G R SG T C+
Sbjct: 569 SCQ----------NGGTCDSVT------------------GACRCPPGVSG---TNCEDG 597
Query: 1302 CGKS-------RECVAPN---------ICKCKPGYIGSNCQTAL----CDPDCKNHGKCI 1341
C K ++C N C C PG G C P C +C+
Sbjct: 598 CPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCV 657
Query: 1342 KPNI---------CQCLPGHGGATCDEE----HCNPPCQHGGTCLAGNLC---------T 1379
+P+ C C G G C E + P C TC G C
Sbjct: 658 QPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKR 717
Query: 1380 CPYGFVGPRCET--------MVCNRHCENGGQCL--TPDICQCKPGWYGPTCST------ 1423
CP GF G C + C+ C GG C+C PG G C
Sbjct: 718 CPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGR 777
Query: 1424 ------ALCDPVCLNGGSCN-KPNTCLCPNGFFGEHCQN---AFCHPP-------CKNGG 1466
+C P C + C+ + CLC GF G CQ+ A + P C N G
Sbjct: 778 WGLGCQEIC-PACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDG 836
Query: 1467 HC-MRNNVCVCREGYTGRRFQKSICD-----PTCMNGGKCVG--------PSTCSCPSGW 1512
HC C C G+TG Q++ CD P C + C C C +G+
Sbjct: 837 HCHPATGHCSCAPGWTGFSCQRA-CDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGY 895
Query: 1513 SGKRCNT--------PICLQK--CKNGGECIAPS-ICHCPSSWEGVRCQIPICNPKCLYG 1561
G RC P C Q+ C++G C S C CP+ W G C+ P +G
Sbjct: 896 VGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHAC--PAGFFG 953
Query: 1562 GRCIFPNVCSCRTEYSGVKCE 1582
C + C+C +G C+
Sbjct: 954 LDC--RSACNCT---AGAACD 969
Score = 94.7 bits (234), Expect = 6e-19
Identities = 93/368 (25%), Positives = 121/368 (32%), Gaps = 109/368 (29%)
Query: 1298 CKYPCGKSRECVAPNI---CKCKPGYIGSNCQTALCDP-----------DCKNHGKCIK- 1342
C + C ++ C+C PG G+NC+ C +C N G+C +
Sbjct: 564 CSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDG-CPKGYYGKHCRKKCNCANRGRCHRL 622
Query: 1343 PNICQCLPGHGGATCD--------EEHCNPPCQ----HGGTC-LAGNLCTCPYGFVGPRC 1389
C C PG G C C+ CQ H +C C+C GF G RC
Sbjct: 623 YGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERC 682
Query: 1390 ETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLN----GGSCNKPNTCLCP 1445
+ +C+ G++GP C A PV + G C K CP
Sbjct: 683 Q-------------------AECELGYFGPGCWQACTCPVGVACDSVSGECGK----RCP 719
Query: 1446 NGFFGEHCQ--------NAFCHPPCKNGGHCMR--NNVCVCREGYTGRRFQ--------- 1486
GF GE C C C GG C C G TG +
Sbjct: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
Query: 1487 ---KSICDPTCMNGGKC---VGPSTC-----------SCPSGWSGKRCNTPICLQKCKNG 1529
+ IC P C + +C G C CP+GW G C T C N
Sbjct: 780 LGCQEIC-PACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRC---SCAND 835
Query: 1530 GEC-IAPSICHCPSSWEGVRCQIPI------------CNPKCLYGGRCIFPNVCSCRTEY 1576
G C A C C W G CQ CN +G +C C Y
Sbjct: 836 GHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGY 895
Query: 1577 SGVKCEKK 1584
G +CE++
Sbjct: 896 VGPRCEQQ 903
Score = 91.3 bits (225), Expect = 7e-18
Identities = 81/286 (28%), Positives = 107/286 (37%), Gaps = 97/286 (33%)
Query: 1356 TCDEEHCNPPCQHGGTCLAG-NLCTCPYGFVGPRCETMVCNR---------------HCE 1399
TCD+ C++GGTCL G + C CP G+ G ++CN C+
Sbjct: 523 TCDD------CRNGGTCLLGLDGCDCPEGWTG-----LICNETCPPDTFGKNCSFSCSCQ 571
Query: 1400 NGGQC-LTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC 1458
NGG C C+C PG G C CP G++G+HC+ C
Sbjct: 572 NGGTCDSVTGACRCPPGVSGTNCEDG-------------------CPKGYYGKHCRKK-C 611
Query: 1459 HPPCKNGGHCMR-NNVCVCREGYTGRRFQKSICDPTCMNGG-----KCVGPST------- 1505
+ C N G C R C+C G G RF C P G +CV P T
Sbjct: 612 N--CANRGRCHRLYGACLCDPGLYG-RFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRD 668
Query: 1506 --CSCPSGWSGKRCNT--------PICLQKC---------KNGGECIAPSICHCPSSWEG 1546
CSC +G+ G+RC P C Q C GEC CP+ ++G
Sbjct: 669 GSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGK----RCPAGFQG 724
Query: 1547 VRC--QIPI------CNPKCLYGGRCI--FPNVCSCRTEYSGVKCE 1582
C + P+ C+ C GG C C +G CE
Sbjct: 725 EDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCE 770
Score = 79.0 bits (193), Expect = 3e-14
Identities = 91/346 (26%), Positives = 120/346 (34%), Gaps = 117/346 (33%)
Query: 1181 CDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNP-------CGLGSYI 1233
C CLNGGSC + C C GF G+ C + + P CG G+
Sbjct: 1219 CGCLNGGSC--------DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC 1270
Query: 1234 SGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
+C CPP + R + N
Sbjct: 1271 DPVTG-TCLCPP----------------------------------GRAGVRCERGCPQN 1295
Query: 1294 AFTI-CKYPCG--KSRECVAPN-ICKCKPGYIGSNCQTALCDP-----------DCKNHG 1338
F + C++ C C A N C C G+ G +C+ A C P C N+
Sbjct: 1296 RFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELA-CPPGRYGAACHLECSCHNNS 1354
Query: 1339 KCIKPN-ICQCLPGHGGATCDEEHCNPP------------CQHGGTC--LAGNLCTCPYG 1383
C C+C PG G C EH PP CQHG C ++G C CP G
Sbjct: 1355 TCEPATGTCRCGPGFYGQAC--EHPCPPGFHGAGCQGLCWCQHGAPCDPISGR-CLCPAG 1411
Query: 1384 FVGPRCETMV--------CNRHCE-NGGQCLTP--DICQCKPGWYGPTCS---------- 1422
F G CE C++ C+ +GG P +C C PG G TC+
Sbjct: 1412 FHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP 1471
Query: 1423 --TALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGG 1466
T CD C G C+ P + C HC + + P C+ GG
Sbjct: 1472 SCTLHCD--CGGGADCD-PVSGQC-------HCVDGYMGPTCREGG 1507
Score = 67.4 bits (163), Expect = 1e-10
Identities = 59/189 (31%), Positives = 78/189 (41%), Gaps = 53/189 (28%)
Query: 1358 DEEHCNPP------CQHGGTCLAGNL--CTCPYGFVGPRCETMVCNRHCENGG---QCL- 1405
DEE C C HGG C+ G+ C CP GF GPRC+ V NGG +C+
Sbjct: 119 DEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVN 178
Query: 1406 TPD--ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHC-------QNA 1456
TP +C+CKPG+ T S +C N+C NG HC
Sbjct: 179 TPGSYLCECKPGFRLHTDSR-----------TCLAINSCALGNGGCQHHCVQLTITRHRC 227
Query: 1457 FCHPPC---KNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCV-GPSTCSCPSGW 1512
C P ++G HC+R + C R G +CM+ + V G + C C G+
Sbjct: 228 QCRPGFQLQEDGRHCVRRSPCANRNG-------------SCMHRCQVVRGLARCECHVGY 274
Query: 1513 ----SGKRC 1517
GK C
Sbjct: 275 QLAADGKAC 283
Score = 62.4 bits (150), Expect = 3e-09
Identities = 53/210 (25%), Positives = 74/210 (35%), Gaps = 68/210 (32%)
Query: 1398 CENGGQCLTP-DICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNA 1456
C NGG CL D C C GW G C+ CP FG++C +
Sbjct: 527 CRNGGTCLLGLDGCDCPEGWTGLICNET-------------------CPPDTFGKNCSFS 567
Query: 1457 FCHPPCKNGGHCMR-NNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGK 1515
C+NGG C C C G +G C +G CP G+ GK
Sbjct: 568 CS---CQNGGTCDSVTGACRCPPGVSGTN---------CEDG----------CPKGYYGK 605
Query: 1516 RCNTPICLQKCKNGGECIAP-SICHCPSSWEGVRCQI--------PICNPKCLYGGRCIF 1566
C C N G C C C G C + P C+ +C +C+
Sbjct: 606 HCRKKC---NCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC----QCVQ 658
Query: 1567 PNV---------CSCRTEYSGVKCEKKIQI 1587
P+ CSC+ + G +C+ + ++
Sbjct: 659 PHTQSCDKRDGSCSCKAGFRGERCQAECEL 688
Score = 61.2 bits (147), Expect = 8e-09
Identities = 80/320 (25%), Positives = 111/320 (34%), Gaps = 70/320 (21%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSY-ISGFHSYSC 1241
C +GG CV PGS C C PGF G C+ D+ C+++ G ++ SY C
Sbjct: 133 CFHGGRCV------PGSA-QPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLC 185
Query: 1242 DCPPELKVETQF-----VN---------QFTTQTVVLTRSD----KSVNKEEDDKNAQGR 1283
+C P ++ T +N Q + +TR +ED ++ R
Sbjct: 186 ECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV-R 244
Query: 1284 KRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYI----GSNCQT--------ALCD 1331
+ +G+ C+ G +R C+C GY G C+ A C
Sbjct: 245 RSPCANRNGSCMHRCQVVRGLAR-------CECHVGYQLAADGKACEDVDECAAGLAQCA 297
Query: 1332 PDCKNHGKCIKPNICQCLPGH----GGATCDE---------EHCNPPCQHGGT-CLAGNL 1377
C N K C C G+ G C E N C HG + AG L
Sbjct: 298 HGCLNTQGSFK---CVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPL 354
Query: 1378 CTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQ--CKPGWYGPTCSTALCDPVCLNGGS 1435
CTCP G+ E R C + C CQ C G C + +G
Sbjct: 355 CTCPRGY-----ELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCG 409
Query: 1436 CNKPNTCLCPNGFFGEHCQN 1455
C + C G HC N
Sbjct: 410 CEDVDECASSRGGCEHHCTN 429
Score = 53.5 bits (127), Expect = 2e-06
Identities = 72/279 (25%), Positives = 95/279 (34%), Gaps = 90/279 (32%)
Query: 1314 CKCKPGYIGSNCQTALCDPDCKNHG-----KCIK---PNICQCLPGHGGATCDEEHCNPP 1365
C C PG+ G CQ + +C+ H +C+ +C+C PG T
Sbjct: 147 CHCPPGFQGPRCQYDV--DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHT--------- 195
Query: 1366 CQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWY----GPTC 1421
TCLA N C G C + RH CQC+PG+ G C
Sbjct: 196 --DSRTCLAINSCALGNGGCQHHCVQLTITRH-----------RCQCRPGFQLQEDGRHC 242
Query: 1422 STALCDPVCLNGGSC-------NKPNTCLCPNGF----FGEHCQN--------AFCHPPC 1462
P GSC C C G+ G+ C++ A C C
Sbjct: 243 VRR--SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC 300
Query: 1463 KNGGHCMRNNVCVCREGY----TGR---RFQKSICDPTCMNGGKC--------VGPSTCS 1507
N + CVC GY GR R + I + N G C GP C+
Sbjct: 301 LNTQGSFK---CVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP-LCT 356
Query: 1508 CPSGW----SGKRC-------NTPICLQKCKN---GGEC 1532
CP G+ + C ++P C Q C N G EC
Sbjct: 357 CPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYEC 395
Score = 37.0 bits (84), Expect = 0.15
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 13/79 (16%)
Query: 1508 CPSGW----SGKRCNTPICLQK-CKNGGECIAPSI--CHCPSSWEGVRCQIPICNPKCLY 1560
C GW + C + C C +GG C+ S CHCP ++G RCQ + +
Sbjct: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHN 169
Query: 1561 GG---RCI---FPNVCSCR 1573
GG RC+ +C C+
Sbjct: 170 GGCQHRCVNTPGSYLCECK 188
Score = 36.6 bits (83), Expect = 0.20
Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 8/55 (14%)
Query: 1494 CMNGGKCVGPST--CSCPSGWSGKRCNTPICLQKCKNGG---ECI---APSICHC 1540
C +GG+CV S C CP G+ G RC + + NGG C+ +C C
Sbjct: 133 CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCEC 187
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 127 bits (320), Expect = 7e-29
Identities = 124/467 (26%), Positives = 178/467 (38%), Gaps = 124/467 (26%)
Query: 1162 LNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISG 1221
L+ DCD ++ S C +CV+ +PG +LC C PG+ G++CE I
Sbjct: 63 LDKDCD-----NMKDPCFSNPCQGSATCVN----TPGERSFLCKCPPGYSGTICETTIGS 113
Query: 1222 CQSNPCGLGSYISGFHSYS-CDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNA 1280
C N C G Y C CP + +F + + D+ A
Sbjct: 114 CGKNSCQHGGICHQDPIYPVCICP------AGYAGRFC--------------EIDHDECA 153
Query: 1281 QGRKRHVKPTSGNAFTICKYPCGKSREC---VAPNICKCKPGYIGSNCQTAL--CDPD-C 1334
PC C + C C PGY G +C + C D C
Sbjct: 154 SS------------------PCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPC 195
Query: 1335 KNHGKCIKP---NICQCLPGHGGATCD---EEHCNPPCQHGGTC---LAGNLCTCPYGFV 1385
KN C+ C C + G C+ +E + PC +G TC L C C GF+
Sbjct: 196 KNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 1386 GPRCE--TMVC-NRHCENGGQCLTPD---ICQCK-PGWYGPTCSTA--LC-DPVCLNGGS 1435
G CE T C ++ C +GG C+ + C C G+ G C T LC C N +
Sbjct: 256 GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNAT 315
Query: 1436 CNKP---NTCLCPNGFFGEHCQ---NAFCHPPCKNGGHCMRNN----------------- 1472
C TC C G+ G C+ N PC++ G C+ +
Sbjct: 316 CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 375
Query: 1473 ------VCVCREGYTGRRFQKSICDPT---CMNGGKCV---GPSTCSCP------SGWSG 1514
VC+C+ G+TG ++ + + + C NGG C G TC CP + + G
Sbjct: 376 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGG 435
Query: 1515 KRCNTPI--CL-QKCKNGGECIAPS-------ICHCPSSWEGVRCQI 1551
+ C+ + C Q+C N G CI C CPS + G C+I
Sbjct: 436 RDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 125 bits (314), Expect = 3e-28
Identities = 117/455 (25%), Positives = 164/455 (36%), Gaps = 125/455 (27%)
Query: 1175 EVTVKSC---DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGS 1231
E T+ SC C +GG C D + +C+C G+ G CE+D C S+PC G+
Sbjct: 108 ETTIGSCGKNSCQHGGICHQDPIYP------VCICPAGYAGRFCEIDHDECASSPCQNGA 161
Query: 1232 YIS-GFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPT 1290
G YSC C P + D V++ D
Sbjct: 162 VCQDGIDGYSCFCVPGYQGR---------------HCDLEVDECASD------------- 193
Query: 1291 SGNAFTICKYPCGKSREC---VAPNICKCKPGYIGSNCQTALCD---PDCKNHGKC---I 1341
PC C + C C Y G NC+ + + C N C +
Sbjct: 194 ----------PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDAL 243
Query: 1342 KPNICQCLPGHGGATCD---EEHCNPPCQHGGTCLAGN---LCTCP-YGFVGPRCETMV- 1393
C C PG G C+ +E + PC HGG C+ G C C GF G CET++
Sbjct: 244 GAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMP 303
Query: 1394 --CNRHCENGGQC---LTPDICQCKPGWYGPTCSTAL--CDP-VCLNGGSCNKPNT---- 1441
++ C N C + C C PG+ G C L C+ C + G C + ++
Sbjct: 304 LCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQY 363
Query: 1442 -------------------CLCPNGFFGEHCQ---NAFCHPPCKNGGHCMR---NNVCVC 1476
C+C GF G HC+ N PC+NGG C N C C
Sbjct: 364 GRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
Query: 1477 ------REGYTGRRFQKSICDPT---CMNGGKCVGPS-------TCSCPSGWSGKRCNTP 1520
R Y GR + T C+N G C+ +C CPSG++G C
Sbjct: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIA 483
Query: 1521 ICLQ-------KCKNGGECIAPSICHCPSSWEGVR 1548
L K+G S+C+ ++ V+
Sbjct: 484 TTLSFEGDGFLWVKSGSVTTKGSVCNIALRFQTVQ 518
Score = 116 bits (290), Expect = 2e-25
Identities = 118/461 (25%), Positives = 174/461 (37%), Gaps = 128/461 (27%)
Query: 1249 VETQFVNQFTTQTVVLTRSDKSVNKE---EDDKNAQGRKRHVKPTSGNAFTIC-KYPCGK 1304
++ F N+ T+ + + + S K+ ++D + ++ N C PC
Sbjct: 22 IKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQG 81
Query: 1305 SRECV-APN----ICKCKPGYIGSNCQTAL------------------------------ 1329
S CV P +CKC PGY G+ C+T +
Sbjct: 82 SATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA 141
Query: 1330 ---CDPD--------CKNHGKC---IKPNICQCLPGHGGATCD---EEHCNPPCQHGGTC 1372
C+ D C+N C I C C+PG+ G CD +E + PC++ TC
Sbjct: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
Query: 1373 L---AGNLCTCPYGFVGPRCETMV---CNRHCENGGQC---LTPDICQCKPGWYGPTC-- 1421
L C CP+ + G CE + ++ C NG C L C C PG+ G C
Sbjct: 202 LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 1422 STALC-DPVCLNGGSC---NKPNTCLCP-NGFFGEHCQNAF---CHPPCKNGGHC---MR 1470
+T C CL+GG C +C C +GF G HC+ PC N C +
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD 321
Query: 1471 NNVCVCREGYTGRRFQKSI--CDPT-CMNGGKCVGPST---------------------- 1505
N C C GYTG + + + C+ C + G+CV S+
Sbjct: 322 NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381
Query: 1506 -CSCPSGWSGKRCNTPI---CLQKCKNGGEC---IAPSICHCP------SSWEGVRCQ-- 1550
C C G++G C + C+NGG C CHCP + + G C
Sbjct: 382 VCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDI 441
Query: 1551 -IPICNPKCLYGGRCIFPNV--------CSCRTEYSGVKCE 1582
+ + +CL G CI P+ C C + Y+G CE
Sbjct: 442 LLGCTHQQCLNNGTCI-PHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 114 bits (286), Expect = 6e-25
Identities = 88/321 (27%), Positives = 133/321 (41%), Gaps = 70/321 (21%)
Query: 1334 CKNHGKCI-----KPNICQCLPGHGGATCDEE--HCNP-PCQHGGTCLAGNL---CTCPY 1382
C+ C+ + +C+C PG+ G C+ C CQHGG C + C CP
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPA 138
Query: 1383 GFVGPRCET---MVCNRHCENGGQC---LTPDICQCKPGWYGPTCSTAL----CDPVCLN 1432
G+ G CE + C+NG C + C C PG+ G C + DP C N
Sbjct: 139 GYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDP-CKN 197
Query: 1433 GGSCNKP---NTCLCPNGFFGEHCQ---NAFCHPPCKNGGHC---MRNNVCVCREGYTGR 1483
+C TC+CP+ + G +C+ + PC NG C + C C G+ G
Sbjct: 198 EATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGD 257
Query: 1484 RFQKSI---CDPTCMNGGKCVGPS---TCSCP-SGWSGKRCNT--PICLQK-CKNGGEC- 1532
+ + C++GG CV +C+C SG++G C T P+C K C N C
Sbjct: 258 HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE 317
Query: 1533 --IAPSICHCPSSWEGVRCQIPI--CNPK-CLYGGRCI-------------FPN------ 1568
+ CHC + G +C+I + CN C G C+ P+
Sbjct: 318 DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHE 377
Query: 1569 ----VCSCRTEYSGVKCEKKI 1585
VC C+ ++G+ CE+ +
Sbjct: 378 ASGYVCICQPGFTGIHCEEDV 398
Score = 82.0 bits (201), Expect = 4e-15
Identities = 62/214 (28%), Positives = 87/214 (40%), Gaps = 42/214 (19%)
Query: 1308 CVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCD---EEHCNP 1364
C+ N+C P G NC+ D H C C G G C+ +E +
Sbjct: 1137 CLQLNVCNSNPCLHGGNCE----DIYSSYH--------CSCPLGWSGKHCELNIDECFSN 1184
Query: 1365 PCQHGGTC--LAGNLCTCPYGFVGPRCETMV--CNRH-CENGGQCLTPD---ICQCKPGW 1416
PC HG +A CTC G+ G CE + C H C NG C++ C C +
Sbjct: 1185 PCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF 1244
Query: 1417 YGPTC-----STALC-----DPVCLNGGSCNKPNT---CLCPNGFFGEHCQ---NAFCHP 1460
G C + +C + C NGG+C + T C+C GF GE C+ +
Sbjct: 1245 TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASD 1304
Query: 1461 PCKNGGHC---MRNNVCVCREGYTGRRFQKSICD 1491
PC NGG C + C+C + G R + + D
Sbjct: 1305 PCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 70.9 bits (172), Expect = 1e-11
Identities = 62/219 (28%), Positives = 80/219 (36%), Gaps = 44/219 (20%)
Query: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCD 1242
CL+GG+C + Y C C G+ G CE++I C SNPC G+ +Y C
Sbjct: 1148 CLHGGNCEDIYSS------YHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCT 1201
Query: 1243 CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPC 1302
C P VN E D N Q + N T +
Sbjct: 1202 CEP---------------------GYTGVNCEVDIDNCQSHQ------CANGATCISHTN 1234
Query: 1303 GKSRECVAPNICK-CKPGYIGSN-CQTALCDPDCKNHGKCIKPNI---CQCLPGHGGATC 1357
G S C K C+ + S C + C N G C + C C PG G C
Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWC 1294
Query: 1358 D---EEHCNPPCQHGGTC---LAGNLCTCPYGFVGPRCE 1390
+ +E + PC +GG C L C C F G RCE
Sbjct: 1295 EKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 67.0 bits (162), Expect = 1e-10
Identities = 57/212 (26%), Positives = 84/212 (39%), Gaps = 48/212 (22%)
Query: 1404 CLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNT---CLCPNGFFGEHCQ---NAF 1457
CL ++C P CL+GG+C + C CP G+ G+HC+ +
Sbjct: 1137 CLQLNVCNSNP---------------CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC 1181
Query: 1458 CHPPCKNGGHCMRNNV--CVCREGYTGRRFQKSI--CDP-TCMNGGKCVGPS---TCSCP 1509
PC +G R C C GYTG + I C C NG C+ + +C C
Sbjct: 1182 FSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCF 1241
Query: 1510 SGWSGKRCN-----TPICLQK-----CKNGGECI---APSICHCPSSWEGVRCQIPI--- 1553
++GK C + +C + C NGG C C C + G C+ I
Sbjct: 1242 GNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC 1301
Query: 1554 CNPKCLYGGRC---IFPNVCSCRTEYSGVKCE 1582
+ C+ GG C + C C ++G +CE
Sbjct: 1302 ASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 63.5 bits (153), Expect = 2e-09
Identities = 54/194 (27%), Positives = 80/194 (41%), Gaps = 45/194 (23%)
Query: 1430 CLNGGSC---NKPNTCLCPN--GFFGEHCQN----AFCHPPCKNGGHCM-----RNNVCV 1475
C N +C +K N C C + + C N F +P C+ C+ R+ +C
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP-CQGSATCVNTPGERSFLCK 97
Query: 1476 CREGYTGRRFQKSICDPT--------CMNGGKC----VGPSTCSCPSGWSGKRC---NTP 1520
C GY+G +IC+ T C +GG C + P C CP+G++G+ C +
Sbjct: 98 CPPGYSG-----TICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
Query: 1521 ICLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI---CNPKCLYGGRC---IFPNVCS 1571
C+NG C I C C ++G C + + + C C I C
Sbjct: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCI 211
Query: 1572 CRTEYSGVKCEKKI 1585
C YSGV CE +I
Sbjct: 212 CPHNYSGVNCELEI 225
Score = 55.8 bits (133), Expect = 3e-07
Identities = 36/113 (31%), Positives = 49/113 (43%), Gaps = 15/113 (13%)
Query: 1486 QKSICDPT-CMNGGKC---VGPSTCSCPSGWSGKRC--NTPICLQKCKNGGEC---IAPS 1536
Q ++C+ C++GG C CSCP GWSGK C N C G C +A
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY 1198
Query: 1537 ICHCPSSWEGVRCQIPICN---PKCLYGGRCIFPN---VCSCRTEYSGVKCEK 1583
C C + GV C++ I N +C G CI C C ++G C +
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
Score = 53.1 bits (126), Expect = 2e-06
Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 27/152 (17%)
Query: 1461 PCKNGGHC---MRNNVCVCREGYTGRRFQKSI--CDPTCMNGGKC---VGPSTCSCPSGW 1512
PC +GG+C + C C G++G+ + +I C G C V C+C G+
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGY 1206
Query: 1513 SGKRCNTPI--CLQ-KCKNGGECIAPS---ICHCPSSWEGVRCQ---IP--IC-----NP 1556
+G C I C +C NG CI+ + C C ++ G C+ +P +C N
Sbjct: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
Query: 1557 KCLYGGRCIFPNV---CSCRTEYSGVKCEKKI 1585
C GG C C CR ++G CEK I
Sbjct: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
Score = 40.8 bits (94), Expect = 0.011
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 14/78 (17%)
Query: 1517 CNTPICLQKCKNGGEC---IAPSICHCPSSWEGVRCQIPI----CNPKCLYGGRC--IFP 1567
CN+ CL +GG C + C CP W G C++ I NP C++G +
Sbjct: 1143 CNSNPCL----HGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAA 1197
Query: 1568 NVCSCRTEYSGVKCEKKI 1585
C+C Y+GV CE I
Sbjct: 1198 YHCTCEPGYTGVNCEVDI 1215
Score = 39.3 bits (90), Expect = 0.031
Identities = 30/117 (25%), Positives = 40/117 (34%), Gaps = 43/117 (36%)
Query: 1170 TRVTIEVTVKSCD---CLNGGSCVSDRN------FSPGSGVYL----------------- 1203
T V EV + +C C NG +C+S N F +G +
Sbjct: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
Query: 1204 ----------------CVCLPGFHGSLCEVDISGCQSNPCGLGSYISG-FHSYSCDC 1243
C+C PGF G CE DI C S+PC G + + C C
Sbjct: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLC 1323
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 125 bits (313), Expect = 4e-28
Identities = 165/636 (25%), Positives = 198/636 (31%), Gaps = 238/636 (37%)
Query: 1164 DDCDAETRVTI--EVTVKSCDCLNGGSCVSDRNFSPGSGVYLCV-----------CLPGF 1210
DDC +E + K C C N SC P SGV C C PG+
Sbjct: 129 DDCSSECAPGMWGPQCDKPCSCGNNSSC------DPKSGVCSCPSGLQPPNCLQPCTPGY 182
Query: 1211 HGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKS 1270
+G C+ C PC + +C CP E + V+ + S S
Sbjct: 183 YGPACQFRCQ-CHGAPCDP-------QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHS 234
Query: 1271 VNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGK-------SRECVAPN---------IC 1314
+ QG G TIC PC + S+EC N C
Sbjct: 235 CQNGGVFQTPQGS---CSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQC 291
Query: 1315 KCKPGYIGSNC--------------QTALCDPDCK----------NHG------------ 1338
+C PGY G C +T C PD + HG
Sbjct: 292 RCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCP 351
Query: 1339 ------KCIKP---------------NICQCLPGHGGATCDE------------EHCNPP 1365
C P C CLPG G C+E EHC
Sbjct: 352 DGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCL-- 409
Query: 1366 CQHGGTCLA-GNLCTCPYGFVGPRCETMV--------CNRHC--ENGGQCLTPD-ICQCK 1413
C HGG C A LC C G+ GP C ++ C+ C EN C D C CK
Sbjct: 410 CLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCK 469
Query: 1414 PGWYGPTCSTALCDPVCLNGGSCN-----------KPNT--CLCPNGFFGEHCQ------ 1454
GW CS C P G SCN P T C C G+ G HCQ
Sbjct: 470 EGWQRGNCSVP-CPPGTW-GFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKG 527
Query: 1455 --------------------------------NAFCHPPC---------------KNGGH 1467
A CH C KNGG
Sbjct: 528 QFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGT 587
Query: 1468 CM-RNNVCVCREGYTGRRFQKSICDP----------TCMNGGKCVGPS--TCSCPSGWSG 1514
C+ N CVC G+ G Q+S C P C N C PS TC C +GW+G
Sbjct: 588 CLPENGNCVCAPGFRGPSCQRS-CQPGRYGKRCVPCKCANHSFC-HPSNGTCYCLAGWTG 645
Query: 1515 KRCNTPI--------CLQ--KCKNGGEC-IAPSICHCPSSWEGVRCQIPICNPKCLYGGR 1563
C+ P C Q +C +GG C C CP W G C + C P +G
Sbjct: 646 PDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHC-LEGC-PLGTFGAN 703
Query: 1564 CIFP-------------NVCSCRTEYSGVKCEKKIQ 1586
C P C C +SG C IQ
Sbjct: 704 CSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
Score = 124 bits (312), Expect = 6e-28
Identities = 105/361 (29%), Positives = 131/361 (36%), Gaps = 86/361 (23%)
Query: 1292 GNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL--------CDPDCK--NHGKC- 1340
G +C C R CVAPN C+C PG+ G +C + CD C N+ C
Sbjct: 99 GFCVPLCAQECVHGR-CVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCD 157
Query: 1341 IKPNICQC----LPGHGGATCDEEHCNPPCQ-----HGGTC-LAGNLCTCPYGFVGPRCE 1390
K +C C P + C + P CQ HG C C CP GP C+
Sbjct: 158 PKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCD 217
Query: 1391 TMV----------CNRHCENGGQCLTPD-ICQCKPGWYGPTCSTALCDPV---------- 1429
C+NGG TP C C PGW G CS +
Sbjct: 218 VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECR 277
Query: 1430 CLNGGSCNK-PNTCLCPNGFFGEHC----------QNAFCHPPCKNGGHCM-RNNVCVCR 1477
C NGG C++ C C G+ G+ C Q+ C C N C+C
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCE 337
Query: 1478 EGYTGRRFQKSICDPTCMNGGKCVGPST---------------CSCPSGWSGKRCNT--- 1519
G+TG R +C P G C P T CSC GW+G CN
Sbjct: 338 HGFTGDRCTDRLC-PDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCP 396
Query: 1520 -----PICLQK--CKNGGECIAPS-ICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCS 1571
P C + C +GG C A S +C C + G C +C P YG C CS
Sbjct: 397 QDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHC-ASLCPPD-TYGVNC--SARCS 452
Query: 1572 C 1572
C
Sbjct: 453 C 453
Score = 115 bits (288), Expect = 3e-25
Identities = 119/456 (26%), Positives = 156/456 (34%), Gaps = 109/456 (23%)
Query: 1182 DCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSC 1241
DC C D P +G C+C GF G C + GF+ SC
Sbjct: 314 DCAETCDCAPDARCFPANGA--CLCEHGFTGDRCTDRLCP------------DGFYGLSC 359
Query: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEED---DKNAQGRKRHVKPTSGNAFTIC 1298
P E ++ E D + G + H G +C
Sbjct: 360 QAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGG---VC 416
Query: 1299 KYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKN---HGKCIKPNICQCLPGHGGA 1355
+ G +C+C PGY G +C +LC PD +C N C P G
Sbjct: 417 QATSG---------LCQCAPGYTGPHC-ASLCPPDTYGVNCSARCSCENAIACSPIDGEC 466
Query: 1356 TCDEE----HCNPPCQHGG---TCLAG-------------NLCTCPYGFVGPRCETMV-- 1393
C E +C+ PC G +C A CTC G+ G C+
Sbjct: 467 VCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPK 526
Query: 1394 ------CNRHCE---NGGQCLTPDICQCKPGWYGPTCSTALCDPV----------CLNGG 1434
C C+ + G CQC+ GW G C + + + C NGG
Sbjct: 527 GQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGG 586
Query: 1435 SCNKPN-TCLCPNGFFGEHCQNAFCHP--------PCKNGGHCM---RNNVCVCREGYTG 1482
+C N C+C GF G CQ + C P PCK H N C C G+TG
Sbjct: 587 TCLPENGNCVCAPGFRGPSCQRS-CQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTG 645
Query: 1483 RRFQKSI--------CDPTCM--NGGKC-VGPSTCSCPSGWSGKRC--NTPI------CL 1523
+ C TC +GG C +C CP GW+G C P+ C
Sbjct: 646 PDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS 705
Query: 1524 QKCKNG-GECIAPSI--CHCPSSWEGVRCQIPICNP 1556
Q C+ G GE P C CP G C+I I P
Sbjct: 706 QPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEP 741
Score = 89.0 bits (219), Expect = 3e-17
Identities = 74/238 (31%), Positives = 98/238 (41%), Gaps = 45/238 (18%)
Query: 1380 CPYGFVGPRCETM-VCNRHCENGGQCLTPDICQCKPGWYGPTCSTAL--------CDPVC 1430
C +GF R + +C + C +G +C+ P+ CQC PGW G CS+ CD C
Sbjct: 90 CCHGFYESRGFCVPLCAQECVHG-RCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPC 148
Query: 1431 L--NGGSCN-KPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQK 1487
N SC+ K C CP+G Q C PC G + C R G
Sbjct: 149 SCGNNSSCDPKSGVCSCPSGL-----QPPNCLQPCTPGYY---GPACQFRCQCHG----- 195
Query: 1488 SICDP---TCMNGGKCVGPST-CSCPSGWSGKRCNTPICLQKCKNGGECIAPS-ICHCPS 1542
+ CDP C + GPS SC G SG C + C+NGG P C CP
Sbjct: 196 APCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPST---HSCQNGGVFQTPQGSCSCPP 252
Query: 1543 SWEGVRCQIPI--------CNPKCLY--GGRCI-FPNVCSCRTEYSGVKCEKKIQIRR 1589
W G C +P C+ +C GG C F C C Y+G +C ++ + R
Sbjct: 253 GWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGR 310
>gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]
Length = 618
Score = 123 bits (308), Expect = 2e-27
Identities = 97/305 (31%), Positives = 121/305 (39%), Gaps = 45/305 (14%)
Query: 1283 RKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL-CDPDCK-NHGKC 1340
R R P G A T P C P + C P + C+ L C C HG C
Sbjct: 175 RARCEPPAVGTACTRLCRPRSAPSRC-GPGLRPCAP--LEDECEAPLVCRAGCSPEHGFC 231
Query: 1341 IKPNICQCLPGHGGATCDEEHCNPPC-QHGGTCLAGNLCTCPYGFVGPR-CETMVCNRHC 1398
+P C+CL G G C C G A C P GP C+ C
Sbjct: 232 EQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVP----GPGPCD----GNPC 283
Query: 1399 ENGGQCL-TPDI--CQCKPGWYGPTCSTA---LCDPVCLNGGSC------NKPNTCLCPN 1446
NGG C TP C C G+YG C + D C NGG C + C CP
Sbjct: 284 ANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPP 343
Query: 1447 GFFGEHCQNAFCH---PPCKNGGHCMRNNV---CVCREGYTGRRFQKSICD---PTCMNG 1497
GF G +C+ PC+NGG C+ C CR G+ G R + + D C NG
Sbjct: 344 GFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANG 403
Query: 1498 GKCV---GPSTCSCPSGWSGKRCNT---PICLQKCKNGGECIAPS---ICHCPSSWEGVR 1548
G CV G CSC G+ G+ C P + C +GG C A +C C + G R
Sbjct: 404 GTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGAR 463
Query: 1549 CQIPI 1553
C+ P+
Sbjct: 464 CEFPV 468
Score = 106 bits (265), Expect = 2e-22
Identities = 93/324 (28%), Positives = 128/324 (39%), Gaps = 91/324 (28%)
Query: 1315 KCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLA 1374
+C+P +G+ C T LC P + +C PG E+ C P C A
Sbjct: 177 RCEPPAVGTAC-TRLCRP---------RSAPSRCGPGLRPCAPLEDECEAPL----VCRA 222
Query: 1375 GNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTC----STALC---- 1426
G C+ +GF CE G+C +C GW GP C ST+ C
Sbjct: 223 G--CSPEHGF-------------CEQPGEC------RCLEGWTGPLCTVPVSTSSCLSPR 261
Query: 1427 ------------------DPVCLNGGSCNK-PNT--CLCPNGFFGEHCQNA---FCHPPC 1462
C NGGSC++ P + C CP GF+G C+ + PC
Sbjct: 262 GPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPC 321
Query: 1463 KNGGHCMRN------NVCVCREGYTGRRFQKSI--CD-PTCMNGGKCVG---PSTCSCPS 1510
NGG C+ +C C G+ G +K + C C NGG C+ C C +
Sbjct: 322 FNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRA 381
Query: 1511 GWSGKRCNTPI--CL-QKCKNGGECI---APSICHCPSSWEGVRCQ---IPICNPKCLYG 1561
G++G RC + C + C NGG C+ C C + G C+ P C +G
Sbjct: 382 GFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHG 441
Query: 1562 GRC---IFPNVCSCRTEYSGVKCE 1582
GRC VC+C Y G +CE
Sbjct: 442 GRCYAHFSGLVCACAPGYMGARCE 465
Score = 80.9 bits (198), Expect = 9e-15
Identities = 68/233 (29%), Positives = 87/233 (37%), Gaps = 68/233 (29%)
Query: 1181 CD---CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISG-- 1235
CD C NGGSC +P S + C C GF+G CEV C PC G G
Sbjct: 278 CDGNPCANGGSCSE----TPRS--FECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGA 331
Query: 1236 --FHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
+Y C CPP + + K D + Q
Sbjct: 332 DPDSAYICHCPPGFQ-------------------GSNCEKRVDRCSLQ------------ 360
Query: 1294 AFTICKYPCGKSRECVAPN---ICKCKPGYIGSNCQTALCD---PDCKNHGKCIK---PN 1344
PC C+ C+C+ G+ G C+ L D C N G C++ +
Sbjct: 361 -------PCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAH 413
Query: 1345 ICQCLPGHGGATCDEEHCNP----PCQHGGTCLA---GNLCTCPYGFVGPRCE 1390
C C G GG C E +P PC HGG C A G +C C G++G RCE
Sbjct: 414 RCSCALGFGGRDC-RERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCE 465
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/194 (26%), Positives = 65/194 (33%), Gaps = 53/194 (27%)
Query: 1176 VTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISG 1235
VT C NGG CV + P S Y+C C PGF GS CE + C PC G
Sbjct: 314 VTCADGPCFNGGLCVGGAD--PDSA-YICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLD 370
Query: 1236 F-HSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNA 1294
H+ C C E D + GR
Sbjct: 371 LGHALRCRC---------------------RAGFAGPRCEHDLDDCAGR----------- 398
Query: 1295 FTICKYPCGKSRECV---APNICKCKPGYIGSNCQTALCDP----DCKNHGKC---IKPN 1344
C CV + C C G+ G +C+ DP C + G+C
Sbjct: 399 ------ACANGGTCVEGGGAHRCSCALGFGGRDCRER-ADPCAARPCAHGGRCYAHFSGL 451
Query: 1345 ICQCLPGHGGATCD 1358
+C C PG+ GA C+
Sbjct: 452 VCACAPGYMGARCE 465
Score = 54.3 bits (129), Expect = 9e-07
Identities = 39/149 (26%), Positives = 51/149 (34%), Gaps = 51/149 (34%)
Query: 1475 VCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPI----CL------- 1523
VCR G C P G C P C C GW+G C P+ CL
Sbjct: 219 VCRAG----------CSP---EHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSS 265
Query: 1524 ---------------QKCKNGGECIAPS---ICHCPSSWEGVRCQ---IPICNPKCLYGG 1562
C NGG C C CP + G+RC+ + + C GG
Sbjct: 266 ATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGG 325
Query: 1563 RCI------FPNVCSCRTEYSGVKCEKKI 1585
C+ +C C + G CEK++
Sbjct: 326 LCVGGADPDSAYICHCPPGFQGSNCEKRV 354
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,391,522
Number of Sequences: 37866
Number of extensions: 3777101
Number of successful extensions: 17065
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 310
Number of HSP's that attempted gapping in prelim test: 7782
Number of HSP's gapped (non-prelim): 4114
length of query: 1590
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1474
effective length of database: 13,855,062
effective search space: 20422361388
effective search space used: 20422361388
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.