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Search of human proteins with 209413728
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 759 0.0
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 738 0.0
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 734 0.0
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 696 0.0
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 334 7e-92
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 333 1e-91
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 179 4e-45
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 178 8e-45
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 174 9e-44
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 146 3e-35
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 125 5e-29
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 87 3e-17
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 85 1e-16
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 84 2e-16
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 84 3e-16
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 77 2e-14
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens] 74 2e-13
gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens] 74 2e-13
gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens] 70 3e-12
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 62 1e-09
gi|157739930 TAP binding protein-like [Homo sapiens] 61 2e-09
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] 60 2e-09
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 56 6e-08
gi|166295173 kin of IRRE like [Homo sapiens] 56 6e-08
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 55 1e-07
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 55 1e-07
gi|90903245 CD200 antigen isoform b [Homo sapiens] 54 2e-07
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens] 54 2e-07
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 52 7e-07
gi|67188443 CD276 antigen isoform a [Homo sapiens] 51 1e-06
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 759 bits (1961), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHVSYSAVSREN 360
PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHVSYSAVSREN
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHVSYSAVSREN 360
Query: 361 SSSQDPQTEGTR 372
SSSQDPQTEGTR
Sbjct: 361 SSSQDPQTEGTR 372
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 738 bits (1905), Expect = 0.0
Identities = 372/417 (89%), Positives = 372/417 (89%), Gaps = 45/417 (10%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG--------------------- 339
PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG 360
Query: 340 ------------------------TEHASASANGHVSYSAVSRENSSSQDPQTEGTR 372
TEHASASANGHVSYSAVSRENSSSQDPQTEGTR
Sbjct: 361 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR 417
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 734 bits (1896), Expect = 0.0
Identities = 364/372 (97%), Positives = 364/372 (97%), Gaps = 8/372 (2%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHVSYSAVSREN 360
PVDKPINTTLICNVTNALGARQAELTVQVK GTEHASASANGHVSYSAVSREN
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVK--------GTEHASASANGHVSYSAVSREN 352
Query: 361 SSSQDPQTEGTR 372
SSSQDPQTEGTR
Sbjct: 353 SSSQDPQTEGTR 364
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 696 bits (1795), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61 VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG 339
PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG 339
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 334 bits (857), Expect = 7e-92
Identities = 180/344 (52%), Positives = 229/344 (66%), Gaps = 19/344 (5%)
Query: 9 WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68
WPLLL+ LL G DV VQ +V G LG +V LPC+L +P + ++S +TW R
Sbjct: 19 WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
Query: 69 HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115
+ +A FH GPS+ S+RL FV+A+ AEL++A+L + GL V
Sbjct: 73 PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
Query: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175
EDEGNYTC F TFP+GS WLRV+AKP+N AE QKV + +P +A C+S GRPPA
Sbjct: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
+I+W S L +QV G L+GTVTVTS + LVPS + DG VTCKVEHESFE+P L+
Sbjct: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
Query: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295
V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G P AVAQG+
Sbjct: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
Query: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG 339
QL+I VD NTT +C VTNA+G +AE + V+E P + +G
Sbjct: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAG 356
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 333 bits (854), Expect = 1e-91
Identities = 179/338 (52%), Positives = 226/338 (66%), Gaps = 19/338 (5%)
Query: 9 WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68
WPLLL+ LL G DV VQ +V G LG +V LPC+L +P + ++S +TW R
Sbjct: 19 WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
Query: 69 HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115
+ +A FH GPS+ S+RL FV+A+ AEL++A+L + GL V
Sbjct: 73 PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
Query: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175
EDEGNYTC F TFP+GS WLRV+AKP+N AE QKV + +P +A C+S GRPPA
Sbjct: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
+I+W S L +QV G L+GTVTVTS + LVPS + DG VTCKVEHESFE+P L+
Sbjct: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
Query: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295
V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G P AVAQG+
Sbjct: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
Query: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
QL+I VD NTT +C VTNA+G +AE + V+E P
Sbjct: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 179 bits (454), Expect = 4e-45
Identities = 119/351 (33%), Positives = 180/351 (51%), Gaps = 25/351 (7%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
+A A W L AL + ++ PG VVQ + GF+G V L C P V
Sbjct: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
Query: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E
Sbjct: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
Query: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G
Sbjct: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
Query: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
+PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V +
Sbjct: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
Query: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
+ LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP
Sbjct: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
Query: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP----PSEH 337
AQ L + P++ + T IC TN +G R ++ V + E P P EH
Sbjct: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEH 345
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 178 bits (451), Expect = 8e-45
Identities = 116/343 (33%), Positives = 177/343 (51%), Gaps = 21/343 (6%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
+A A W L AL + ++ PG VVQ + GF+G V L C P V
Sbjct: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
Query: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E
Sbjct: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
Query: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G
Sbjct: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
Query: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
+PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V +
Sbjct: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
Query: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
+ LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP
Sbjct: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
Query: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
AQ L + P++ + T IC TN +G R ++ V + E P
Sbjct: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 174 bits (442), Expect = 9e-44
Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
+A A W L AL + ++ PG VVQ + GF+G V L C P V
Sbjct: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
Query: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E
Sbjct: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
Query: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G
Sbjct: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
Query: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
+PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V +
Sbjct: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
Query: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
+ LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP
Sbjct: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
Query: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329
AQ L + P++ + T IC TN +G R ++ V +
Sbjct: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 146 bits (369), Expect = 3e-35
Identities = 99/329 (30%), Positives = 154/329 (46%), Gaps = 16/329 (4%)
Query: 11 LLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR-H 69
LLL LL+ S ++ P V G +V+L C ++V ++Q++W + H
Sbjct: 41 LLLFPLLLFSRLCGALAGPIIVEP-HVTAVWGKNVSLKCLIEVNET----ITQISWEKIH 95
Query: 70 GESGSMAVFHQTQGPSYSESKRLEFVAARL--GAELRNASLRMFGLRVEDEGNYTCLFVT 127
G+S H P Y S + E+ L L +A++ + + D G Y C VT
Sbjct: 96 GKSSQTVAVHH---PQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVT 152
Query: 128 FPQGSRSVDIWLRVLAKPQNTAEVQKVQLT--GEPVPMARCVSTGGRPPAQITWHSDLGG 185
FP G+ + VL +P + L G A C++ G+P A I W DLG
Sbjct: 153 FPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGE 212
Query: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPE 245
M +T+ F + T T+ S + L P+ G+ +TC V+H + EK + L + Y PE
Sbjct: 213 MESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270
Query: 246 VSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQL-LIRPVDK 304
VS++GYD NW++G+ L C+A +NP P WS G P +A L + P+
Sbjct: 271 VSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTF 330
Query: 305 PINTTLICNVTNALGARQAELTVQVKEGP 333
+ IC VTN+LG R + + + + P
Sbjct: 331 NYSGVYICKVTNSLGQRSDQKVIYISDPP 359
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 125 bits (315), Expect = 5e-29
Identities = 104/350 (29%), Positives = 155/350 (44%), Gaps = 23/350 (6%)
Query: 8 AWPLLLVALLVLSWPPPG----TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQ 63
AW LLL+ L + P T DVV LG LPC+ + + E V Q
Sbjct: 14 AWLLLLLLLASFTGRCPAGELETSDVVTVV-------LGQDAKLPCFYRGDSGE--QVGQ 64
Query: 64 LTWAR--HGESGS-MAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
+ WAR GE +A+ H G S + + S+ + DEG
Sbjct: 65 VAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGE 124
Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Y C TFP GS + LRVL P + G+ + +A + G P +TW
Sbjct: 125 YECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWD 184
Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
+++ G TS S + VTS + LVPS ++G+ +TC V H + Q +T L V
Sbjct: 185 TEVKG--TTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHV 242
Query: 241 YYPPEVSISGYD--NNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLL 298
+ E S+ G + N W++G+ A L C + P P+ YNW+ GPLP G L
Sbjct: 243 SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSGVRVDGDTLG 301
Query: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASAN 348
P+ + +C+V+N +R +++TV V + P E SG + SA+
Sbjct: 302 FPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD--PQEDSGKQVDLVSAS 349
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 86.7 bits (213), Expect = 3e-17
Identities = 98/355 (27%), Positives = 144/355 (40%), Gaps = 46/355 (12%)
Query: 7 AAWPLLLVALLVLSWPP-----------PGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN 55
AA LLL+ L W P P T D V A G +V L C QV +
Sbjct: 5 AASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--------GGTVVLKC--QVKD 54
Query: 56 MEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAEL-RNASLRMFGLR 114
E S L W+ + Q + E + L +L S+ + +
Sbjct: 55 HED---SSLQWSNPAQ----------QTLYFGEKRALRDNRIQLVTSTPHELSISISNVA 101
Query: 115 VEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRP 173
+ DEG YTC T P + ++S+ L + KP T K L + C S+G +P
Sbjct: 102 LADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLNCQSSGSKP 159
Query: 174 PAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
A++TW +L G P Q T TV+S + + DG ++ C V HES +
Sbjct: 160 AARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
Query: 231 PQLLT-VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPF 289
T + V Y P I + GQ + L C+ R NP P Y W G +PP
Sbjct: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEKE-GSVPPL 276
Query: 290 AVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKE-GPPSEHSGTEHA 343
+ Q + L+ ++K + T C T+ +G+ +A T+ V + P S T HA
Sbjct: 277 KMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHA 331
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 84.7 bits (208), Expect = 1e-16
Identities = 71/243 (29%), Positives = 109/243 (44%), Gaps = 11/243 (4%)
Query: 107 SLRMFGLRVEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR 165
S+ + + + DEG YTC T P + ++S+ L + KP T K L +
Sbjct: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLN 185
Query: 166 CVSTGGRPPAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCK 222
C S+G +P A++TW +L G P Q T TV+S + + DG ++ C
Sbjct: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCS 244
Query: 223 VEHESFEKPQLLT-VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
V HES + T + V Y P I + GQ + L C+ R NP P Y W
Sbjct: 245 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEK 303
Query: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKE-GPPSEHSGT 340
G +PP + Q + L+ ++K + T C T+ +G+ +A T+ V + P S T
Sbjct: 304 E-GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSST 362
Query: 341 EHA 343
HA
Sbjct: 363 YHA 365
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 84.3 bits (207), Expect = 2e-16
Identities = 94/340 (27%), Positives = 138/340 (40%), Gaps = 27/340 (7%)
Query: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
Query: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
V QL + F + S + L F ++ L L N S + DE
Sbjct: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
Query: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
Query: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
G L I ++K N T C +N +G ++ + V + P
Sbjct: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 83.6 bits (205), Expect = 3e-16
Identities = 96/358 (26%), Positives = 141/358 (39%), Gaps = 27/358 (7%)
Query: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
Query: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
V QL + F + S + L F ++ L L N S + DE
Sbjct: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
Query: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
Query: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHV 351
G L I ++K N T C +N +G ++ + V + E + G V
Sbjct: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGV 352
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 77.0 bits (188), Expect = 2e-14
Identities = 69/245 (28%), Positives = 104/245 (42%), Gaps = 21/245 (8%)
Query: 101 AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEP 160
A S+ + + + DEG YTC T P ++ +L VL P +K Q++G
Sbjct: 84 ASWHELSISVSDVSLSDEGQYTCSLFTMP--VKTSKAYLTVLGVP------EKPQISGFS 135
Query: 161 VPMAR-------CVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSG--TVTVTSLWILVPS 211
P+ C ++G +P A I W + + + + + T TV+S
Sbjct: 136 SPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVD 195
Query: 212 SQVDGKNVTCKVEHESFE-KPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARS 270
DG V C+V+HES PQ+ L ++Y P V I GQ LTC+++
Sbjct: 196 RSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQ-PLILTCESKG 254
Query: 271 NPEPTGYNWSTTMG--PLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQ 328
P P W+ G P P V G +L I ++K N T C TN +G AE +
Sbjct: 255 KPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLI 314
Query: 329 VKEGP 333
V + P
Sbjct: 315 VHDVP 319
>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
Length = 708
Score = 73.9 bits (180), Expect = 2e-13
Identities = 90/367 (24%), Positives = 137/367 (37%), Gaps = 51/367 (13%)
Query: 10 PLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARH 69
P LLV L G +Q P + LG+ LPC L + + W +
Sbjct: 7 PALLVLLFCFRGRA-GPSPHFLQQPEDLVVLLGEEARLPCALGA------YWGLVQWTKS 59
Query: 70 GESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFP 129
G +A+ Q P +S +++ + +R + +EDE +Y C
Sbjct: 60 G----LALGGQRDLPGWSRY----WISGNAANGQHDLHIRP--VELEDEASYECQATQ-- 107
Query: 130 QGSRSVDIWLRVLAKPQNTAEV--QKVQLTGEPVPMARCVSTG-GRPPAQITWHSD---L 183
G RS L VL P+ + V L C S G RP ++ W D L
Sbjct: 108 AGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLL 167
Query: 184 GGMPNTSQV-----PGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNL 238
G + PG + T+T+T P S DG C+ ++ + + L
Sbjct: 168 DGATFHQTLLKEGTPGSVESTLTLT------PFSHDDGATFVCRARSQALPTGRDTAITL 221
Query: 239 TVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPL-----PPFAVAQ 293
++ YPPEV++S + G+ + C A + P TGY W+ P+ P V
Sbjct: 222 SLQYPPEVTLSASPHTVQEGE-KVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVA 280
Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHVSY 353
A L PV C V+NA+G+ + V GP + + E S S+
Sbjct: 281 DASFLTEPVS--------CEVSNAVGSANRSTALDVLFGPILQ-AKPEPVSVDVGEDASF 331
Query: 354 SAVSREN 360
S R N
Sbjct: 332 SCAWRGN 338
>gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]
Length = 633
Score = 73.9 bits (180), Expect = 2e-13
Identities = 90/367 (24%), Positives = 137/367 (37%), Gaps = 51/367 (13%)
Query: 10 PLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARH 69
P LLV L G +Q P + LG+ LPC L + + W +
Sbjct: 7 PALLVLLFCFRGRA-GPSPHFLQQPEDLVVLLGEEARLPCALGA------YWGLVQWTKS 59
Query: 70 GESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFP 129
G +A+ Q P +S +++ + +R + +EDE +Y C
Sbjct: 60 G----LALGGQRDLPGWSRY----WISGNAANGQHDLHIRP--VELEDEASYECQATQ-- 107
Query: 130 QGSRSVDIWLRVLAKPQNTAEV--QKVQLTGEPVPMARCVSTG-GRPPAQITWHSD---L 183
G RS L VL P+ + V L C S G RP ++ W D L
Sbjct: 108 AGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLL 167
Query: 184 GGMPNTSQV-----PGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNL 238
G + PG + T+T+T P S DG C+ ++ + + L
Sbjct: 168 DGATFHQTLLKEGTPGSVESTLTLT------PFSHDDGATFVCRARSQALPTGRDTAITL 221
Query: 239 TVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPL-----PPFAVAQ 293
++ YPPEV++S + G+ + C A + P TGY W+ P+ P V
Sbjct: 222 SLQYPPEVTLSASPHTVQEGE-KVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVA 280
Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHVSY 353
A L PV C V+NA+G+ + V GP + + E S S+
Sbjct: 281 DASFLTEPVS--------CEVSNAVGSANRSTALDVLFGPILQ-AKPEPVSVDVGEDASF 331
Query: 354 SAVSREN 360
S R N
Sbjct: 332 SCAWRGN 338
>gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]
Length = 583
Score = 70.1 bits (170), Expect = 3e-12
Identities = 69/264 (26%), Positives = 102/264 (38%), Gaps = 34/264 (12%)
Query: 113 LRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEV--QKVQLTGEPVPMARCVSTG 170
+ +EDE +Y C G RS L VL P+ + V L C S G
Sbjct: 43 VELEDEASYECQATQ--AGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRG 100
Query: 171 -GRPPAQITWHSD---LGGMPNTSQV-----PGFLSGTVTVTSLWILVPSSQVDGKNVTC 221
RP ++ W D L G + PG + T+T+T P S DG C
Sbjct: 101 DARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLT------PFSHDDGATFVC 154
Query: 222 KVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
+ ++ + + L++ YPPEV++S + G+ + C A + P TGY W+
Sbjct: 155 RARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGE-KVIFLCQATAQPPVTGYRWAK 213
Query: 282 TMGPL-----PPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSE 336
P+ P V A L PV C V+NA+G+ + V GP +
Sbjct: 214 GGSPVLGARGPRLEVVADASFLTEPVS--------CEVSNAVGSANRSTALDVLFGPILQ 265
Query: 337 HSGTEHASASANGHVSYSAVSREN 360
+ E S S+S R N
Sbjct: 266 -AKPEPVSVDVGEDASFSCAWRGN 288
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 61.6 bits (148), Expect = 1e-09
Identities = 83/335 (24%), Positives = 127/335 (37%), Gaps = 45/335 (13%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
M RA WPLLL+ PG G V Q N+ V
Sbjct: 1 MGRARRFQWPLLLLWAAAAG---PGAGQEV---------------------QTENVTVAE 36
Query: 61 --VSQLTWARHGESGSMAVFHQT--QGPSYSESKRLEFVAARLGA-ELRNASLRMFGLRV 115
V+++T H GS+ V Q ++ ++ L+ +L R +R+ R+
Sbjct: 37 GGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARL 96
Query: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQN-TAEVQKVQLTGEPVPMARCVSTGGRPP 174
EDEG Y C T + + L VL P+N EV++ + G V ++ C+ RP
Sbjct: 97 EDEGGYFCQLYT--EDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELS-CLVPRSRPA 153
Query: 175 AQITWHSD---LGGMPNTSQVPGFLSGTV-TVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
A + W+ D L G+ ++ + +G V +V S + DG + C+ ++++
Sbjct: 154 ATLRWYRDRKELKGVSSSQE-----NGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPS 208
Query: 231 PQLLTVN--LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPP 288
L V Y P I G LTC NP P W+ LP
Sbjct: 209 GHSKQTQYVLDVQYSPTARIHASQAVVREGDT-LVLTCAVTGNPRPNQIRWNRGNESLPE 267
Query: 289 FAVAQGAQLLIRPVDKPINTTLICNVTNALGARQA 323
A A G L + + N T C +N G +A
Sbjct: 268 RAEAVGETLTLPGLVSADNGTYTCEASNKHGHARA 302
>gi|157739930 TAP binding protein-like [Homo sapiens]
Length = 468
Score = 60.8 bits (146), Expect = 2e-09
Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 21/211 (9%)
Query: 31 VQAPTQVPGFL-GDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSE 88
V TQ FL G S +L C + P +++ V W + V+ T G +
Sbjct: 193 VMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVE---WRLQHKGRGQLVYSWTAGQGQAV 249
Query: 89 SKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNT 148
K A+LG R+ASL + GL ++DEG Y C T ++ + I L + A P+
Sbjct: 250 RKGATLEPAQLGMA-RDASLTLPGLTIQDEGTYICQITTSLYRAQQI-IQLNIQASPKVR 307
Query: 149 AEVQKVQLTGEPVPMARCVSTGGRP-PAQITW-HSDLGGMP------NTSQVPGFLSGTV 200
+ L +P C G P +TW +LGG P + S + ++GT
Sbjct: 308 LSLANEAL----LPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTY 363
Query: 201 TVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
+++S P S G TC+V H S E+P
Sbjct: 364 SISSSLTAEPGSA--GATYTCQVTHISLEEP 392
>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
Length = 526
Score = 60.5 bits (145), Expect = 2e-09
Identities = 62/230 (26%), Positives = 99/230 (43%), Gaps = 13/230 (5%)
Query: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDV-VVQAPTQVPGFLGDSVTLPCYLQVPNMEVT 59
MA ++ P L+ L++L P + V+ P + +G+ LPC L PN
Sbjct: 1 MAVFPSSGLPRCLLTLILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLS-PNASAE 59
Query: 60 HVSQLTWARHGESGSMAVFH--QTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVED 117
H+ +L W R S ++ V + Q R + G +LR+ G+RV D
Sbjct: 60 HL-ELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSD 118
Query: 118 EGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQI 177
+G YTC F ++ + L+V A + +VQ GE C S G P Q+
Sbjct: 119 DGEYTCFFREDGSYEEAL-VHLKVAALGSDPHISMQVQENGE--ICLECTSVGWYPEPQV 175
Query: 178 TWHSDLG-GMPNTSQVPG-FLSGTVTVTSLWILVPSSQVDGKNVTCKVEH 225
W + G P+TS+ G TV + I+ +S KNV+C +++
Sbjct: 176 QWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTS---AKNVSCYIQN 222
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 55.8 bits (133), Expect = 6e-08
Identities = 76/269 (28%), Positives = 109/269 (40%), Gaps = 45/269 (16%)
Query: 86 YSESKRLEFVAARLGAELRNASLRMFGLRVE-DEGNYTCLFVTFPQGSRSVDIWLRVLAK 144
Y S L F ++ E N +L++ ++ E DEG YTC + PQ S S + + V
Sbjct: 538 YKNSNLLPFNHRQVAFE-NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 596
Query: 145 P-QNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGT---V 200
P E + + G+ V CV G P ITW D G P +PG L T +
Sbjct: 597 PFIQPFEFPRFSI-GQRV-FIPCVVVSGDLPITITWQKD--GRP----IPGSLGVTIDNI 648
Query: 201 TVTSLWILVPSSQVDGKNVTC-------KVEHESFEKPQLLTVNLTVYYPPEVSISGYDN 253
TS + S + N TC VEH+S L V PP+ + D
Sbjct: 649 DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQS---------QLIVRVPPKFVVQPRDQ 699
Query: 254 NWYLGQNEATLTCDARSNPEPTGYNWSTTMGP-LPPF---------AVAQGAQLLIRPVD 303
+ G+ L C A P PT W + G +P F V LLI+ V
Sbjct: 700 DGIYGK-AVILNCSAEGYPVPT-IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVV 757
Query: 304 KPINTTLICNVTNALGA---RQAELTVQV 329
+ + +C V+N +GA + LTV++
Sbjct: 758 EEDSGYYLCKVSNDVGADVSKSMYLTVKI 786
Score = 35.0 bits (79), Expect = 0.11
Identities = 54/236 (22%), Positives = 89/236 (37%), Gaps = 18/236 (7%)
Query: 129 PQGS-RSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCV--STGGRPPAQITWHSDLGG 185
P G RS D+ ++ + + T V+ + V + +C+ S+ ++W D
Sbjct: 107 PSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVS 166
Query: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK-NVTCKVEHE-SFEKPQLLTVNLTVYYP 243
+ + S+ FL +T T + DG N C H + E Q + L V P
Sbjct: 167 LVSGSR---FL---ITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDP 220
Query: 244 PEVS---ISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQG--AQLL 298
+ + G+D+ + L C A +PEP Y W PL Q LL
Sbjct: 221 ANSAPSILDGFDHRKAMAGQRVELPCKALGHPEP-DYRWLKDNMPLELSGRFQKTVTGLL 279
Query: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHVSYS 354
I + + + +C V+N G + + VK+ P +S VS S
Sbjct: 280 IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQ-PLKATISPRKVKSSVGSQVSLS 334
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 55.8 bits (133), Expect = 6e-08
Identities = 68/286 (23%), Positives = 109/286 (38%), Gaps = 48/286 (16%)
Query: 12 LLVALLVLSWP-PPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHG 70
LLV +L LS GT Q P G LPC L + + + W + G
Sbjct: 4 LLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVL------LNYSGIVQWTKDG 57
Query: 71 ESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQ 130
+ M G R V + A+ +L + + D+ +Y C
Sbjct: 58 LALGM-------GQGLKAWPRYRVVGS---ADAGQYNLEITDAELSDDASYECQATEAAL 107
Query: 131 GSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR--------CVSTGGRPPAQITWHSD 182
SR L VL P++T ++ G PV + + C + +P A I W D
Sbjct: 108 RSRRAK--LTVLIPPEDT------RIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRD 159
Query: 183 LGGMPNTSQVPGFLSGTV--------TVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLL 234
+Q G ++ T T S ++ P+ G+ TC+ +E+ +
Sbjct: 160 ------GTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSGKET 213
Query: 235 TVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWS 280
++ L V++PP V++S G+ TC A +NPE GY W+
Sbjct: 214 SIELDVHHPPTVTLSIEPQTVQEGE-RVVFTCQATANPEILGYRWA 258
>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
Length = 600
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/241 (22%), Positives = 99/241 (41%), Gaps = 32/241 (13%)
Query: 108 LRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT---GEPVPMA 164
L++ ++D+ Y C + SR L VL P + + ++ G+P+ +
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPAR--LTVLVPPDDPVILGGPVISLRAGDPLNLT 169
Query: 165 RCVSTGGRPPAQITWHSDLGGMPNTSQVPGFL---SGTVTVTSLWILVPSSQVDGKNVTC 221
C + +P A I W G + N + L ++ S + P +G+++ C
Sbjct: 170 -CHADNAKPAASIIWLRK-GEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVC 227
Query: 222 KVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
+ +++ + +V + + +PP V++S + L N T C A++NP T Y W
Sbjct: 228 RATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRW-- 284
Query: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTT---------LICNVTNALGARQAELTVQVKEG 332
A+ Q++ + TT + C VTNALG+ TV V G
Sbjct: 285 ----------AKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFG 334
Query: 333 P 333
P
Sbjct: 335 P 335
Score = 28.9 bits (63), Expect = 7.8
Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 107 SLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARC 166
+L + +R ED G Y C V G+ ++ L V P ++ + L GE +C
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEK-GQIKC 440
Query: 167 VSTGGRPPAQITW 179
PP +I W
Sbjct: 441 FIRSTPPPDRIAW 453
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/241 (22%), Positives = 99/241 (41%), Gaps = 32/241 (13%)
Query: 108 LRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT---GEPVPMA 164
L++ ++D+ Y C + SR L VL P + + ++ G+P+ +
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPAR--LTVLVPPDDPVILGGPVISLRAGDPLNLT 169
Query: 165 RCVSTGGRPPAQITWHSDLGGMPNTSQVPGFL---SGTVTVTSLWILVPSSQVDGKNVTC 221
C + +P A I W G + N + L ++ S + P +G+++ C
Sbjct: 170 -CHADNAKPAASIIWLRK-GEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVC 227
Query: 222 KVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
+ +++ + +V + + +PP V++S + L N T C A++NP T Y W
Sbjct: 228 RATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRW-- 284
Query: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTT---------LICNVTNALGARQAELTVQVKEG 332
A+ Q++ + TT + C VTNALG+ TV V G
Sbjct: 285 ----------AKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFG 334
Query: 333 P 333
P
Sbjct: 335 P 335
Score = 28.9 bits (63), Expect = 7.8
Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 107 SLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARC 166
+L + +R ED G Y C V G+ ++ L V P ++ + L GE +C
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEK-GQIKC 440
Query: 167 VSTGGRPPAQITW 179
PP +I W
Sbjct: 441 FIRSTPPPDRIAW 453
>gi|90903245 CD200 antigen isoform b [Homo sapiens]
Length = 294
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 9/153 (5%)
Query: 74 SMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSR 133
+M F + G + + + +LG L+N+++ + + +EDEG Y CLF TF G
Sbjct: 99 NMVTFSENHGVVIQPAYKDKINITQLG--LQNSTITFWNITLEDEGCYMCLFNTFGFGKI 156
Query: 134 SVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVP 193
S L V +P + + + S RP + W G+ N++
Sbjct: 157 SGTACLTVYVQP-----IVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTL 211
Query: 194 GFLSGTVTVTS-LWILVPSSQVDGKNVTCKVEH 225
+GT +VTS L I P +QV GK V C+V H
Sbjct: 212 SHPNGTTSVTSILHIKDPKNQV-GKEVICQVLH 243
>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
Length = 269
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 9/153 (5%)
Query: 74 SMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSR 133
+M F + G + + + +LG L+N+++ + + +EDEG Y CLF TF G
Sbjct: 74 NMVTFSENHGVVIQPAYKDKINITQLG--LQNSTITFWNITLEDEGCYMCLFNTFGFGKI 131
Query: 134 SVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVP 193
S L V +P + + + S RP + W G+ N++
Sbjct: 132 SGTACLTVYVQP-----IVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTL 186
Query: 194 GFLSGTVTVTS-LWILVPSSQVDGKNVTCKVEH 225
+GT +VTS L I P +QV GK V C+V H
Sbjct: 187 SHPNGTTSVTSILHIKDPKNQV-GKEVICQVLH 218
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 52.4 bits (124), Expect = 7e-07
Identities = 81/334 (24%), Positives = 128/334 (38%), Gaps = 57/334 (17%)
Query: 19 LSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVF 78
L++P T + ++ P+ G ++ L C VP +H +Q+TW + G GS+ V
Sbjct: 2333 LAYPAGSTQPIRIE-PSSSQVAEGQTLDLNCV--VPGQ--SH-AQVTWHKRG--GSLPVR 2384
Query: 79 HQTQGP-----SYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSR 133
HQT G S + E+V LG+ + + + + +E G+ L VT
Sbjct: 2385 HQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVL--VTIEPAGSVPALGVTPT---- 2438
Query: 134 SVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVP 193
+R+ + AE Q + L C+ G+ AQ+TWH G +P QV
Sbjct: 2439 -----VRIESSSSQVAEGQTLDLN--------CL-VAGQAHAQVTWHKRGGSLPARHQVH 2484
Query: 194 GFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLT----------VYYP 243
G + VT D C+V S + + V + V YP
Sbjct: 2485 GSRLRLLQVTP---------ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYP 2535
Query: 244 PEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVD 303
+ S + L C S P W G LP G++L I V
Sbjct: 2536 VRIESSSAS---LANGHTLDLNCLVASQA-PHTITWYKRGGSLPSRHQIVGSRLRIPQVT 2591
Query: 304 KPINTTLICNVTNALGARQAELTVQVKEGPPSEH 337
+ +C+V+N G+R+ L V + +G S H
Sbjct: 2592 PADSGEYVCHVSNGAGSRETSLIVTI-QGSGSSH 2624
Score = 50.4 bits (119), Expect = 2e-06
Identities = 72/311 (23%), Positives = 111/311 (35%), Gaps = 57/311 (18%)
Query: 62 SQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNY 121
+Q+TW + G GS+ HQ +G + L +F D G Y
Sbjct: 2274 AQVTWYKRG--GSLPARHQVRG----------------------SRLYIFQASPADAGQY 2309
Query: 122 TCLFVTFPQGSRSVDIWLRV---LAKPQNTAEVQKVQLTGEPVPMARCVSTG----GRPP 174
C + S +V + LA P + + +++ + V + + G+
Sbjct: 2310 VCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSH 2369
Query: 175 AQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHES--FEKPQ 232
AQ+TWH G +P Q G SL L +S D C+V S E
Sbjct: 2370 AQVTWHKRGGSLPVRHQTHG---------SLLRLYQASPADSGEYVCRVLGSSVPLEASV 2420
Query: 233 LLTVNLTVYYP-----PEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLP 287
L+T+ P P V I + GQ L C W G LP
Sbjct: 2421 LVTIEPAGSVPALGVTPTVRIESSSSQVAEGQT-LDLNCLVAGQAHAQ-VTWHKRGGSLP 2478
Query: 288 PFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHS-------GT 340
G++L + V + +C V + G ++A + V +++ HS
Sbjct: 2479 ARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRI 2538
Query: 341 EHASAS-ANGH 350
E +SAS ANGH
Sbjct: 2539 ESSSASLANGH 2549
Score = 49.7 bits (117), Expect = 4e-06
Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 262 ATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGAR 321
ATL C A +P PT +WS PLP +G L+I V + + ICN T+ G
Sbjct: 3229 ATLRCSATGSPAPT-IHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHA 3287
Query: 322 QAELTVQVKEGPPSEHSGTEHASASANGHVSYSAVS 357
+A + + V E PP + EHAS A V ++
Sbjct: 3288 EATIILHV-ESPPYATTVPEHASVQAGETVQLQCLA 3322
Score = 47.0 bits (110), Expect = 3e-05
Identities = 70/293 (23%), Positives = 109/293 (37%), Gaps = 49/293 (16%)
Query: 62 SQLTWARHGESGSMAVFHQTQGPSY-----SESKRLEFVAARLGAELRNASLRMFGLRVE 116
+Q+TW + G GS+ HQT+G S + E+V +G+ + L L
Sbjct: 2756 AQVTWHKRG--GSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGS---SGPLEASVLVTI 2810
Query: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQ 176
+ + + V P G+ + R+ AE Q + L +CV G+ AQ
Sbjct: 2811 EASGSSAVHVPAPGGAPPI----RIEPSSSRVAEGQTLDL--------KCV-VPGQAHAQ 2857
Query: 177 ITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTV 236
+TWH G +P QV G L L S D +C+V S + V
Sbjct: 2858 VTWHKRGGNLPARHQVHG---------PLLRLNQVSPADSGEYSCQVTGSSGTLEASVLV 2908
Query: 237 NLTVYYPPEVSISGYDNNWYLGQNEATLT----------CDARSNPEPTGYNWSTTMGPL 286
+ P + G Y+ + + +T +++ + T W G L
Sbjct: 2909 TIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVT---WYKRGGSL 2965
Query: 287 PPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQ-AELTVQVKEGPPSEHS 338
P G+QL + V + +C + G Q A TV V PPSE S
Sbjct: 2966 PARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTV---PPSEGS 3015
Score = 43.5 bits (101), Expect = 3e-04
Identities = 56/248 (22%), Positives = 95/248 (38%), Gaps = 20/248 (8%)
Query: 101 AELRNASLRMFGLRVEDEGNYTCLFVTFP--QGSRSVDIWLRVLAKPQNTAEVQKVQLTG 158
A++ LR+ + D+ Y C + Q +R+V + + P+ ++ Q+
Sbjct: 1911 AQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAV-LHVHGGGGPRVQVSPERTQVHA 1969
Query: 159 EPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPS-SQVDGK 217
C G P A ITW + G +P P S + +L L+P+ + D
Sbjct: 1970 GRTVRLYC-RAAGVPSATITWRKEGGSLP-----PQARSERTDIATL--LIPAITTADAG 2021
Query: 218 NVTCKVEHESFE---KPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEP 274
C + + Q++ ++ + PP V I + GQ L C +
Sbjct: 2022 FYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQT-LDLNCVVAGSAHA 2080
Query: 275 TGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPP 334
W G LPP G++L + V + +C V N G ++A +TV V G
Sbjct: 2081 Q-VTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHG-- 2137
Query: 335 SEHSGTEH 342
HSG +
Sbjct: 2138 -THSGPSY 2144
Score = 39.7 bits (91), Expect = 0.004
Identities = 67/300 (22%), Positives = 105/300 (35%), Gaps = 74/300 (24%)
Query: 64 LTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTC 123
+TW + G GS+ HQT G + LR+ + V D G Y C
Sbjct: 2661 ITWYKRG--GSLPSRHQTHG----------------------SHLRLHQMSVADSGEYVC 2696
Query: 124 --------------LFVTFPQGSRSV---DIWLRVLAKPQNTAEVQKVQLTGEPVPMARC 166
+ V+ GS S + +R+ + + AE + + L C
Sbjct: 2697 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLN--------C 2748
Query: 167 VSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHE 226
V G+ AQ+TWH G +P+ Q G S L S D C+V
Sbjct: 2749 V-VPGQAHAQVTWHKRGGSLPSHHQTRG---------SRLRLHHVSPADSGEYVCRVMGS 2798
Query: 227 S--FEKPQLLTVNLT----VYYP-----PEVSISGYDNNWYLGQN-EATLTCDARSNPEP 274
S E L+T+ + V+ P P + I + GQ + +++ +
Sbjct: 2799 SGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2858
Query: 275 TGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPP 334
T W G LP G L + V + C VT + G +A + V ++ P
Sbjct: 2859 T---WHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSP 2915
Score = 37.7 bits (86), Expect = 0.017
Identities = 70/279 (25%), Positives = 103/279 (36%), Gaps = 44/279 (15%)
Query: 62 SQLTWARHGESGSMAVFHQTQG-----PSYSESKRLEFVA-ARLGAELRNASLRMFGLRV 115
+Q+TW R G GS+ Q G P S + E+V G+ + AS+ + L
Sbjct: 2080 AQVTWYRRG--GSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHG 2137
Query: 116 EDEG-NYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPP 174
G +YT + P +R + R+ + AE Q + L CV G+
Sbjct: 2138 THSGPSYTPV----PGSTRPI----RIEPSSSHVAEGQTLDLN--------CV-VPGQAH 2180
Query: 175 AQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHES--FEKPQ 232
AQ+TWH G +P Q G SL L + D C V S E
Sbjct: 2181 AQVTWHKRGGSLPARHQTHG---------SLLRLHQVTPADSGEYVCHVVGTSGPLEASV 2231
Query: 233 LLTVNLTVYYP--PEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFA 290
L+T+ +V P V I + GQ L+C W G LP
Sbjct: 2232 LVTIEASVIPGPIPPVRIESSSSTVAEGQT-LDLSCVVAGQAH-AQVTWYKRGGSLPARH 2289
Query: 291 VAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQV 329
+G++L I +C +N + +A +TV V
Sbjct: 2290 QVRGSRLYIFQASPADAGQYVCRASNGM---EASITVTV 2325
Score = 37.0 bits (84), Expect = 0.029
Identities = 58/291 (19%), Positives = 103/291 (35%), Gaps = 59/291 (20%)
Query: 62 SQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNY 121
+Q+TW + G GS+ HQT G + LR+ + D G Y
Sbjct: 2954 AQVTWYKRG--GSLPARHQTHG----------------------SQLRLHLVSPADSGEY 2989
Query: 122 TCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMA---------RCVSTGGR 172
C + P + + V ++ ++ ++ +P +C+ G
Sbjct: 2990 VCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGA 3049
Query: 173 PPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQ 232
P + W + + + + +G++ I + ++ V ++ Q
Sbjct: 3050 APISLEWKTRNQELEDNVHISP--NGSI------ITIVGTRPSNHGTYRCVASNAYGVAQ 3101
Query: 233 LLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWS-----------T 281
+ VNL+V+ PP VS+ W TL C + P + W+
Sbjct: 3102 SV-VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSA-RWTRISSTPAKLEQR 3159
Query: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEG 332
T G + AV Q + +P D T +C NALG Q ++ V V G
Sbjct: 3160 TYGLMDSHAVLQISS--AKPSDA---GTYVCLAQNALGTAQKQVEVIVDTG 3205
Score = 35.8 bits (81), Expect = 0.064
Identities = 56/239 (23%), Positives = 87/239 (36%), Gaps = 28/239 (11%)
Query: 100 GAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQ---KVQL 156
G +++ LR+ L +G Y C P G L + A P ++ + +
Sbjct: 3443 GHSVQDGVLRIQNLDQSCQGTYICQ-AHGPWGKAQASAQLVIQALPSVLINIRTSVQTVV 3501
Query: 157 TGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDG 216
G V C++ G P Q+TW S +GG V G V + + + D
Sbjct: 3502 VGHAVEF-ECLALGD-PKPQVTW-SKVGGHLRPGIVQS--GGVVRIAHVEL------ADA 3550
Query: 217 KNVTCKVEHES--FEKPQLLTVNLT--VYYPPEVSISGYDNNWYLGQNEATLTCDARSNP 272
C + + + LL V + P EV + + A C A P
Sbjct: 3551 GQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPA--------GSAAVFPCIASGYP 3602
Query: 273 EPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKE 331
P +WS G LPP + + L++ V T +C TN G +A +QV E
Sbjct: 3603 TPD-ISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPE 3660
Score = 30.4 bits (67), Expect = 2.7
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 266 CDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAEL 325
C A +P+P WS G L P V G + I V+ C TNA G Q+ +
Sbjct: 3510 CLALGDPKPQ-VTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHV 3568
Query: 326 TVQVKEGP 333
+ V+ P
Sbjct: 3569 LLLVQALP 3576
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 51.2 bits (121), Expect = 1e-06
Identities = 53/172 (30%), Positives = 75/172 (43%), Gaps = 12/172 (6%)
Query: 26 TGDVVVQAPTQ-VPGFLGDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQ--T 81
TG V VQ P V +G TL C + P + ++ L W + F +
Sbjct: 244 TGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLN-LIWQLTDTKQLVHSFTEGRD 302
Query: 82 QGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRV 141
QG +Y+ L G NASLR+ +RV DEG++TC GS +V + +
Sbjct: 303 QGSAYANRTALFPDLLAQG----NASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAA 358
Query: 142 -LAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQV 192
+KP T E K G+ V + C S G P A++ W D G+P T V
Sbjct: 359 PYSKPSMTLEPNKDLRPGDTVTIT-CSSYRGYPEAEVFW-QDGQGVPLTGNV 408
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/172 (30%), Positives = 75/172 (43%), Gaps = 12/172 (6%)
Query: 26 TGDVVVQAPTQ-VPGFLGDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFH--QT 81
TG + VQ P V +G TL C + P + ++ L W + F Q
Sbjct: 26 TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLN-LIWQLTDTKQLVHSFAEGQD 84
Query: 82 QGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRV 141
QG +Y+ L G NASLR+ +RV DEG++TC GS +V + +
Sbjct: 85 QGSAYANRTALFPDLLAQG----NASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAA 140
Query: 142 -LAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQV 192
+KP T E K G+ V + C S G P A++ W D G+P T V
Sbjct: 141 PYSKPSMTLEPNKDLRPGDTVTIT-CSSYQGYPEAEVFW-QDGQGVPLTGNV 190
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,191,504
Number of Sequences: 37866
Number of extensions: 771724
Number of successful extensions: 2631
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 207
Number of HSP's that attempted gapping in prelim test: 2098
Number of HSP's gapped (non-prelim): 622
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.