Guide to the Human Genome
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Search of human proteins with 209413726

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
         (417 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]         853   0.0  
gi|209413732 poliovirus receptor isoform delta [Homo sapiens]         793   0.0  
gi|209413728 poliovirus receptor isoform beta [Homo sapiens]          738   0.0  
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]         702   0.0  
gi|5360210 poliovirus receptor related 2 isoform alpha precursor...   336   3e-92
gi|112789532 poliovirus receptor related 2 isoform delta precurs...   336   3e-92
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]    184   2e-46
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]    183   3e-46
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]    174   1e-43
gi|11386199 poliovirus receptor-related 3 [Homo sapiens]              146   3e-35
gi|222136611 poliovirus receptor-related 4 [Homo sapiens]             130   3e-30
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]         96   5e-20
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          94   2e-19
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho...    91   2e-18
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho...    84   2e-16
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]       77   3e-14
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]               72   7e-13
gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]               72   7e-13
gi|21686977 cell adhesion molecule 4 [Homo sapiens]                    70   5e-12
gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]               69   1e-11
gi|157739930 TAP binding protein-like [Homo sapiens]                   61   2e-09
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]       60   3e-09
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42...    56   7e-08
gi|166295173 kin of IRRE like [Homo sapiens]                           56   7e-08
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]               55   2e-07
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]                55   2e-07
gi|90903245 CD200 antigen isoform b [Homo sapiens]                     54   2e-07
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]           54   2e-07
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             52   8e-07
gi|67188443 CD276 antigen isoform a [Homo sapiens]                     51   2e-06

>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
          Length = 417

 Score =  853 bits (2205), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
           VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120

Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
           YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180

Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
           SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240

Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
           YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300

Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG 360
           PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG 360

Query: 361 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR 417
           IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
Sbjct: 361 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR 417


>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
          Length = 392

 Score =  793 bits (2049), Expect = 0.0
 Identities = 386/389 (99%), Positives = 386/389 (99%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
           VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120

Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
           YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180

Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
           SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240

Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
           YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300

Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG 360
           PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG 360

Query: 361 IGIYFYWSKCSREVLWHCHLCPSSTEHAS 389
           IGIYFYWSKCSREVLWHCHLCPSS  H S
Sbjct: 361 IGIYFYWSKCSREVLWHCHLCPSSEHHQS 389


>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
          Length = 372

 Score =  738 bits (1905), Expect = 0.0
 Identities = 372/417 (89%), Positives = 372/417 (89%), Gaps = 45/417 (10%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
           VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120

Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
           YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180

Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
           SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240

Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
           YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300

Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG 360
           PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG                     
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG--------------------- 339

Query: 361 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR 417
                                   TEHASASANGHVSYSAVSRENSSSQDPQTEGTR
Sbjct: 340 ------------------------TEHASASANGHVSYSAVSRENSSSQDPQTEGTR 372


>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
          Length = 364

 Score =  702 bits (1811), Expect = 0.0
 Identities = 358/417 (85%), Positives = 360/417 (86%), Gaps = 53/417 (12%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
           VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
Sbjct: 61  VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120

Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
           YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180

Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
           SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240

Query: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300
           YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
Sbjct: 241 YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR 300

Query: 301 PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLG 360
           PVDKPINTTLICNVTNALGARQAELTVQVK    +EH+  S N                 
Sbjct: 301 PVDKPINTTLICNVTNALGARQAELTVQVK---GTEHASASAN----------------- 340

Query: 361 IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR 417
                                            GHVSYSAVSRENSSSQDPQTEGTR
Sbjct: 341 ---------------------------------GHVSYSAVSRENSSSQDPQTEGTR 364


>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
           [Homo sapiens]
          Length = 479

 Score =  336 bits (861), Expect = 3e-92
 Identities = 186/372 (50%), Positives = 242/372 (65%), Gaps = 23/372 (6%)

Query: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72

Query: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132

Query: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192

Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252

Query: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312

Query: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLG--IL 353
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P +    +    +++  +G  +L
Sbjct: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDV--GPLVWGAVGGTLL 370

Query: 354 VFLILLGIGIYF 365
           V L+L G  + F
Sbjct: 371 VLLLLAGGSLAF 382


>gi|112789532 poliovirus receptor related 2 isoform delta precursor
           [Homo sapiens]
          Length = 538

 Score =  336 bits (861), Expect = 3e-92
 Identities = 182/358 (50%), Positives = 235/358 (65%), Gaps = 19/358 (5%)

Query: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72

Query: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132

Query: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192

Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252

Query: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312

Query: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGIL 353
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P +  +G +   I  ++  I+
Sbjct: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGGIIAAII 370


>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
          Length = 517

 Score =  184 bits (466), Expect = 2e-46
 Identities = 130/378 (34%), Positives = 195/378 (51%), Gaps = 29/378 (7%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           +A A    W L   AL + ++  PG    VVQ    + GF+G  V L C    P   V  
Sbjct: 6   LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61

Query: 61  VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
           ++Q+TW +  +G   ++A+++ + G S      +R+EF    L     + ++R+  L +E
Sbjct: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117

Query: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
           DEG Y C F TFP G+R   + L V+AKP N  E  +  L       + V +A C S  G
Sbjct: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177

Query: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
           +PP+ ++W + L G     ++    +GTVTV S + LVPS +   +++ C V +      
Sbjct: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236

Query: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
           + LT+N  V Y PEV+I G+D NWYL + +  LTC A +NP  T Y+W+T  G LP    
Sbjct: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294

Query: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP----PSEH---SGISRN 343
           AQ   L  + P++  +  T IC  TN +G R  ++ V + E P    P EH   +G    
Sbjct: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPT 354

Query: 344 AIIFLVLG-ILVFLILLG 360
           AII  V G IL+ LI++G
Sbjct: 355 AIIGGVAGSILLVLIVVG 372


>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
          Length = 458

 Score =  183 bits (464), Expect = 3e-46
 Identities = 126/377 (33%), Positives = 192/377 (50%), Gaps = 25/377 (6%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           +A A    W L   AL + ++  PG    VVQ    + GF+G  V L C    P   V  
Sbjct: 6   LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61

Query: 61  VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
           ++Q+TW +  +G   ++A+++ + G S      +R+EF    L     + ++R+  L +E
Sbjct: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117

Query: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
           DEG Y C F TFP G+R   + L V+AKP N  E  +  L       + V +A C S  G
Sbjct: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177

Query: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
           +PP+ ++W + L G     ++    +GTVTV S + LVPS +   +++ C V +      
Sbjct: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236

Query: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
           + LT+N  V Y PEV+I G+D NWYL + +  LTC A +NP  T Y+W+T  G LP    
Sbjct: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294

Query: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP-PSEHSGISRNAIIFLV 349
           AQ   L  + P++  +  T IC  TN +G R  ++ V + E P P    G   +A   L 
Sbjct: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLG---SAARLLA 351

Query: 350 LGILVFLILLGIGIYFY 366
             + VFLIL+ +   F+
Sbjct: 352 GTVAVFLILVAVLTVFF 368


>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
          Length = 352

 Score =  174 bits (442), Expect = 1e-43
 Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           +A A    W L   AL + ++  PG    VVQ    + GF+G  V L C    P   V  
Sbjct: 6   LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61

Query: 61  VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
           ++Q+TW +  +G   ++A+++ + G S      +R+EF    L     + ++R+  L +E
Sbjct: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117

Query: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
           DEG Y C F TFP G+R   + L V+AKP N  E  +  L       + V +A C S  G
Sbjct: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177

Query: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
           +PP+ ++W + L G     ++    +GTVTV S + LVPS +   +++ C V +      
Sbjct: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236

Query: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
           + LT+N  V Y PEV+I G+D NWYL + +  LTC A +NP  T Y+W+T  G LP    
Sbjct: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294

Query: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329
           AQ   L  + P++  +  T IC  TN +G R  ++ V +
Sbjct: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333


>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
          Length = 549

 Score =  146 bits (369), Expect = 3e-35
 Identities = 99/329 (30%), Positives = 154/329 (46%), Gaps = 16/329 (4%)

Query: 11  LLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR-H 69
           LLL  LL+ S         ++  P  V    G +V+L C ++V       ++Q++W + H
Sbjct: 41  LLLFPLLLFSRLCGALAGPIIVEP-HVTAVWGKNVSLKCLIEVNET----ITQISWEKIH 95

Query: 70  GESGSMAVFHQTQGPSYSESKRLEFVAARL--GAELRNASLRMFGLRVEDEGNYTCLFVT 127
           G+S      H    P Y  S + E+    L     L +A++ +  +   D G Y C  VT
Sbjct: 96  GKSSQTVAVHH---PQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVT 152

Query: 128 FPQGSRSVDIWLRVLAKPQNTAEVQKVQLT--GEPVPMARCVSTGGRPPAQITWHSDLGG 185
           FP G+      + VL +P  +       L   G     A C++  G+P A I W  DLG 
Sbjct: 153 FPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGE 212

Query: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPE 245
           M +T+    F + T T+ S + L P+    G+ +TC V+H + EK    +  L + Y PE
Sbjct: 213 MESTTT--SFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270

Query: 246 VSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQL-LIRPVDK 304
           VS++GYD NW++G+    L C+A +NP P    WS   G  P   +A    L  + P+  
Sbjct: 271 VSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTF 330

Query: 305 PINTTLICNVTNALGARQAELTVQVKEGP 333
             +   IC VTN+LG R  +  + + + P
Sbjct: 331 NYSGVYICKVTNSLGQRSDQKVIYISDPP 359


>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
          Length = 510

 Score =  130 bits (326), Expect = 3e-30
 Identities = 107/366 (29%), Positives = 164/366 (44%), Gaps = 28/366 (7%)

Query: 8   AWPLLLVALLVLSWPPPG----TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQ 63
           AW LLL+ L   +   P     T DVV          LG    LPC+ +  + E   V Q
Sbjct: 14  AWLLLLLLLASFTGRCPAGELETSDVVTVV-------LGQDAKLPCFYRGDSGE--QVGQ 64

Query: 64  LTWAR--HGESGS-MAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
           + WAR   GE    +A+ H   G   S +               + S+ +      DEG 
Sbjct: 65  VAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGE 124

Query: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
           Y C   TFP GS    + LRVL  P  +         G+ + +A   +  G P   +TW 
Sbjct: 125 YECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWD 184

Query: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
           +++ G   TS      S +  VTS + LVPS  ++G+ +TC V H    + Q +T  L V
Sbjct: 185 TEVKG--TTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHV 242

Query: 241 YYPPEVSISGYD--NNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLL 298
            +  E S+ G +  N W++G+  A L C +   P P+ YNW+   GPLP      G  L 
Sbjct: 243 SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSGVRVDGDTLG 301

Query: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG-----ISRNAIIFLVLGIL 353
             P+    +   +C+V+N   +R +++TV V +  P E SG     +S + ++  V+  L
Sbjct: 302 FPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD--PQEDSGKQVDLVSASVVVVGVIAAL 359

Query: 354 VFLILL 359
           +F +L+
Sbjct: 360 LFCLLV 365


>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
          Length = 398

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 102/370 (27%), Positives = 155/370 (41%), Gaps = 45/370 (12%)

Query: 7   AAWPLLLVALLVLSWPP-----------PGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPN 55
           AA  LLL+ L    W P           P T D  V A        G +V L C  QV +
Sbjct: 5   AASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVA--------GGTVVLKC--QVKD 54

Query: 56  MEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAEL-RNASLRMFGLR 114
            E    S L W+   +          Q   + E + L     +L        S+ +  + 
Sbjct: 55  HED---SSLQWSNPAQ----------QTLYFGEKRALRDNRIQLVTSTPHELSISISNVA 101

Query: 115 VEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRP 173
           + DEG YTC   T P + ++S+   L +  KP  T    K  L  +      C S+G +P
Sbjct: 102 LADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLNCQSSGSKP 159

Query: 174 PAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
            A++TW     +L G P   Q       T TV+S      + + DG ++ C V HES + 
Sbjct: 160 AARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218

Query: 231 PQLLTVN-LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPF 289
               T   + V Y P   I     +   GQ +  L C+ R NP P  Y W    G +PP 
Sbjct: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEKE-GSVPPL 276

Query: 290 AVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLV 349
            + Q + L+   ++K  + T  C  T+ +G+ +A  T+ V +  P   S  + +AII  +
Sbjct: 277 KMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGI 336

Query: 350 LGILVFLILL 359
           +  +VFL+L+
Sbjct: 337 VAFIVFLLLI 346


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 75/258 (29%), Positives = 120/258 (46%), Gaps = 10/258 (3%)

Query: 107 SLRMFGLRVEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR 165
           S+ +  + + DEG YTC   T P + ++S+   L +  KP  T    K  L  +      
Sbjct: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLN 185

Query: 166 CVSTGGRPPAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCK 222
           C S+G +P A++TW     +L G P   Q       T TV+S      + + DG ++ C 
Sbjct: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCS 244

Query: 223 VEHESFEKPQLLTVN-LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
           V HES +     T   + V Y P   I     +   GQ +  L C+ R NP P  Y W  
Sbjct: 245 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEK 303

Query: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGIS 341
             G +PP  + Q + L+   ++K  + T  C  T+ +G+ +A  T+ V +  P   S  +
Sbjct: 304 E-GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSST 362

Query: 342 RNAIIFLVLGILVFLILL 359
            +AII  ++  +VFL+L+
Sbjct: 363 YHAIIGGIVAFIVFLLLI 380


>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 104/377 (27%), Positives = 156/377 (41%), Gaps = 32/377 (8%)

Query: 2   ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
           A A AAA P L + LL+L +       TGD        V    G+  T+ C +   N   
Sbjct: 14  AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70

Query: 59  THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
             V QL       +     F   +    S  + L F ++ L   L N S       + DE
Sbjct: 71  DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119

Query: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
           G Y C L+   PQ S +    + VL  P+N   ++QK   + GE + +  C +   +P  
Sbjct: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175

Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
            I W      +   S+V  + S   TVTS  +L    + DG  V C+VEH +        
Sbjct: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234

Query: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
             L V Y P+V I   Y       + +A  LTC+A   P+P    W      +P  AV  
Sbjct: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294

Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISR--NAIIFLVLG 351
           G  L I  ++K  N T  C  +N +G   ++  + V +    E   I    +A+I  V+ 
Sbjct: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVA 354

Query: 352 ILVF---LILLGIGIYF 365
           ++VF    +L+ +G YF
Sbjct: 355 VVVFAMLCLLIILGRYF 371


>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 94/340 (27%), Positives = 138/340 (40%), Gaps = 27/340 (7%)

Query: 2   ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
           A A AAA P L + LL+L +       TGD        V    G+  T+ C +   N   
Sbjct: 14  AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70

Query: 59  THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
             V QL       +     F   +    S  + L F ++ L   L N S       + DE
Sbjct: 71  DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119

Query: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
           G Y C L+   PQ S +    + VL  P+N   ++QK   + GE + +  C +   +P  
Sbjct: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175

Query: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
            I W      +   S+V  + S   TVTS  +L    + DG  V C+VEH +        
Sbjct: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234

Query: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
             L V Y P+V I   Y       + +A  LTC+A   P+P    W      +P  AV  
Sbjct: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294

Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
           G  L I  ++K  N T  C  +N +G   ++  + V + P
Sbjct: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334


>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
          Length = 437

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 69/245 (28%), Positives = 104/245 (42%), Gaps = 21/245 (8%)

Query: 101 AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEP 160
           A     S+ +  + + DEG YTC   T P   ++   +L VL  P      +K Q++G  
Sbjct: 84  ASWHELSISVSDVSLSDEGQYTCSLFTMP--VKTSKAYLTVLGVP------EKPQISGFS 135

Query: 161 VPMAR-------CVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSG--TVTVTSLWILVPS 211
            P+         C ++G +P A I W  +   + +   +    +   T TV+S       
Sbjct: 136 SPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVD 195

Query: 212 SQVDGKNVTCKVEHESFE-KPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARS 270
              DG  V C+V+HES    PQ+    L ++Y P V I         GQ    LTC+++ 
Sbjct: 196 RSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQ-PLILTCESKG 254

Query: 271 NPEPTGYNWSTTMG--PLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQ 328
            P P    W+   G  P P   V  G +L I  ++K  N T  C  TN +G   AE  + 
Sbjct: 255 KPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLI 314

Query: 329 VKEGP 333
           V + P
Sbjct: 315 VHDVP 319


>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
          Length = 708

 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 84/340 (24%), Positives = 128/340 (37%), Gaps = 50/340 (14%)

Query: 10  PLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARH 69
           P LLV L        G     +Q P  +   LG+   LPC L        +   + W + 
Sbjct: 7   PALLVLLFCFRGRA-GPSPHFLQQPEDLVVLLGEEARLPCALGA------YWGLVQWTKS 59

Query: 70  GESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFP 129
           G    +A+  Q   P +S      +++        +  +R   + +EDE +Y C      
Sbjct: 60  G----LALGGQRDLPGWSRY----WISGNAANGQHDLHIRP--VELEDEASYECQATQ-- 107

Query: 130 QGSRSVDIWLRVLAKPQNTAEV--QKVQLTGEPVPMARCVSTG-GRPPAQITWHSD---L 183
            G RS    L VL  P+    +    V L         C S G  RP  ++ W  D   L
Sbjct: 108 AGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLL 167

Query: 184 GGMPNTSQV-----PGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNL 238
            G      +     PG +  T+T+T      P S  DG    C+   ++    +   + L
Sbjct: 168 DGATFHQTLLKEGTPGSVESTLTLT------PFSHDDGATFVCRARSQALPTGRDTAITL 221

Query: 239 TVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPL-----PPFAVAQ 293
           ++ YPPEV++S   +    G+ +    C A + P  TGY W+    P+     P   V  
Sbjct: 222 SLQYPPEVTLSASPHTVQEGE-KVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVA 280

Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
            A  L  PV         C V+NA+G+      + V  GP
Sbjct: 281 DASFLTEPVS--------CEVSNAVGSANRSTALDVLFGP 312


>gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]
          Length = 633

 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 84/340 (24%), Positives = 128/340 (37%), Gaps = 50/340 (14%)

Query: 10  PLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARH 69
           P LLV L        G     +Q P  +   LG+   LPC L        +   + W + 
Sbjct: 7   PALLVLLFCFRGRA-GPSPHFLQQPEDLVVLLGEEARLPCALGA------YWGLVQWTKS 59

Query: 70  GESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFP 129
           G    +A+  Q   P +S      +++        +  +R   + +EDE +Y C      
Sbjct: 60  G----LALGGQRDLPGWSRY----WISGNAANGQHDLHIRP--VELEDEASYECQATQ-- 107

Query: 130 QGSRSVDIWLRVLAKPQNTAEV--QKVQLTGEPVPMARCVSTG-GRPPAQITWHSD---L 183
            G RS    L VL  P+    +    V L         C S G  RP  ++ W  D   L
Sbjct: 108 AGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLL 167

Query: 184 GGMPNTSQV-----PGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNL 238
            G      +     PG +  T+T+T      P S  DG    C+   ++    +   + L
Sbjct: 168 DGATFHQTLLKEGTPGSVESTLTLT------PFSHDDGATFVCRARSQALPTGRDTAITL 221

Query: 239 TVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPL-----PPFAVAQ 293
           ++ YPPEV++S   +    G+ +    C A + P  TGY W+    P+     P   V  
Sbjct: 222 SLQYPPEVTLSASPHTVQEGE-KVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVA 280

Query: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
            A  L  PV         C V+NA+G+      + V  GP
Sbjct: 281 DASFLTEPVS--------CEVSNAVGSANRSTALDVLFGP 312


>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
          Length = 388

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 95/371 (25%), Positives = 143/371 (38%), Gaps = 46/371 (12%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
           M RA    WPLLL+         PG G  V                     Q  N+ V  
Sbjct: 1   MGRARRFQWPLLLLWAAAAG---PGAGQEV---------------------QTENVTVAE 36

Query: 61  --VSQLTWARHGESGSMAVFHQT--QGPSYSESKRLEFVAARLGA-ELRNASLRMFGLRV 115
             V+++T   H   GS+ V      Q   ++ ++ L+    +L     R   +R+   R+
Sbjct: 37  GGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARL 96

Query: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQN-TAEVQKVQLTGEPVPMARCVSTGGRPP 174
           EDEG Y C   T  + +      L VL  P+N   EV++  + G  V ++ C+    RP 
Sbjct: 97  EDEGGYFCQLYT--EDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELS-CLVPRSRPA 153

Query: 175 AQITWHSD---LGGMPNTSQVPGFLSGTV-TVTSLWILVPSSQVDGKNVTCKVEHESFEK 230
           A + W+ D   L G+ ++ +     +G V +V S        + DG  + C+ ++++   
Sbjct: 154 ATLRWYRDRKELKGVSSSQE-----NGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPS 208

Query: 231 PQLLTVN--LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPP 288
                    L V Y P   I         G     LTC    NP P    W+     LP 
Sbjct: 209 GHSKQTQYVLDVQYSPTARIHASQAVVREGDT-LVLTCAVTGNPRPNQIRWNRGNESLPE 267

Query: 289 FAVAQGAQLLIRPVDKPINTTLICNVTNALG-ARQAELTVQVKEGPPSEHSGISRNAIIF 347
            A A G  L +  +    N T  C  +N  G AR   + V    G   E       AI+ 
Sbjct: 268 RAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTSVPYAIVG 327

Query: 348 LVLGILVFLIL 358
            +L +LVFLI+
Sbjct: 328 GILALLVFLII 338


>gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]
          Length = 583

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 63/237 (26%), Positives = 93/237 (39%), Gaps = 33/237 (13%)

Query: 113 LRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEV--QKVQLTGEPVPMARCVSTG 170
           + +EDE +Y C       G RS    L VL  P+    +    V L         C S G
Sbjct: 43  VELEDEASYECQATQ--AGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRG 100

Query: 171 -GRPPAQITWHSD---LGGMPNTSQV-----PGFLSGTVTVTSLWILVPSSQVDGKNVTC 221
             RP  ++ W  D   L G      +     PG +  T+T+T      P S  DG    C
Sbjct: 101 DARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLT------PFSHDDGATFVC 154

Query: 222 KVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
           +   ++    +   + L++ YPPEV++S   +    G+ +    C A + P  TGY W+ 
Sbjct: 155 RARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGE-KVIFLCQATAQPPVTGYRWAK 213

Query: 282 TMGPL-----PPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
              P+     P   V   A  L  PV         C V+NA+G+      + V  GP
Sbjct: 214 GGSPVLGARGPRLEVVADASFLTEPVS--------CEVSNAVGSANRSTALDVLFGP 262


>gi|157739930 TAP binding protein-like [Homo sapiens]
          Length = 468

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 21/211 (9%)

Query: 31  VQAPTQVPGFL-GDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSE 88
           V   TQ   FL G S +L C +   P +++  V    W    +     V+  T G   + 
Sbjct: 193 VMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVE---WRLQHKGRGQLVYSWTAGQGQAV 249

Query: 89  SKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNT 148
            K      A+LG   R+ASL + GL ++DEG Y C   T    ++ + I L + A P+  
Sbjct: 250 RKGATLEPAQLGMA-RDASLTLPGLTIQDEGTYICQITTSLYRAQQI-IQLNIQASPKVR 307

Query: 149 AEVQKVQLTGEPVPMARCVSTGGRP-PAQITW-HSDLGGMP------NTSQVPGFLSGTV 200
             +    L    +P   C   G  P    +TW   +LGG P      + S +   ++GT 
Sbjct: 308 LSLANEAL----LPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTY 363

Query: 201 TVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
           +++S     P S   G   TC+V H S E+P
Sbjct: 364 SISSSLTAEPGSA--GATYTCQVTHISLEEP 392


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 62/230 (26%), Positives = 99/230 (43%), Gaps = 13/230 (5%)

Query: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDV-VVQAPTQVPGFLGDSVTLPCYLQVPNMEVT 59
           MA   ++  P  L+ L++L  P   +    V+  P  +   +G+   LPC L  PN    
Sbjct: 1   MAVFPSSGLPRCLLTLILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLS-PNASAE 59

Query: 60  HVSQLTWARHGESGSMAVFH--QTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVED 117
           H+ +L W R   S ++ V    + Q        R      + G      +LR+ G+RV D
Sbjct: 60  HL-ELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSD 118

Query: 118 EGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQI 177
           +G YTC F        ++ + L+V A   +     +VQ  GE      C S G  P  Q+
Sbjct: 119 DGEYTCFFREDGSYEEAL-VHLKVAALGSDPHISMQVQENGE--ICLECTSVGWYPEPQV 175

Query: 178 TWHSDLG-GMPNTSQVPG-FLSGTVTVTSLWILVPSSQVDGKNVTCKVEH 225
            W +  G   P+TS+       G  TV +  I+  +S    KNV+C +++
Sbjct: 176 QWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTS---AKNVSCYIQN 222


>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
           precursor [Homo sapiens]
          Length = 2012

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 76/269 (28%), Positives = 109/269 (40%), Gaps = 45/269 (16%)

Query: 86  YSESKRLEFVAARLGAELRNASLRMFGLRVE-DEGNYTCLFVTFPQGSRSVDIWLRVLAK 144
           Y  S  L F   ++  E  N +L++  ++ E DEG YTC  +  PQ S S  + + V   
Sbjct: 538 YKNSNLLPFNHRQVAFE-NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 596

Query: 145 P-QNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGT---V 200
           P     E  +  + G+ V    CV   G  P  ITW  D  G P    +PG L  T   +
Sbjct: 597 PFIQPFEFPRFSI-GQRV-FIPCVVVSGDLPITITWQKD--GRP----IPGSLGVTIDNI 648

Query: 201 TVTSLWILVPSSQVDGKNVTC-------KVEHESFEKPQLLTVNLTVYYPPEVSISGYDN 253
             TS   +   S +   N TC        VEH+S          L V  PP+  +   D 
Sbjct: 649 DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQS---------QLIVRVPPKFVVQPRDQ 699

Query: 254 NWYLGQNEATLTCDARSNPEPTGYNWSTTMGP-LPPF---------AVAQGAQLLIRPVD 303
           +   G+    L C A   P PT   W  + G  +P F          V     LLI+ V 
Sbjct: 700 DGIYGK-AVILNCSAEGYPVPT-IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVV 757

Query: 304 KPINTTLICNVTNALGA---RQAELTVQV 329
           +  +   +C V+N +GA   +   LTV++
Sbjct: 758 EEDSGYYLCKVSNDVGADVSKSMYLTVKI 786



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 49/213 (23%), Positives = 83/213 (38%), Gaps = 17/213 (7%)

Query: 129 PQGS-RSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCV--STGGRPPAQITWHSDLGG 185
           P G  RS D+ ++ + +   T  V+  +     V + +C+  S+       ++W  D   
Sbjct: 107 PSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVS 166

Query: 186 MPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK-NVTCKVEHE-SFEKPQLLTVNLTVYYP 243
           + + S+   FL   +T T    +      DG  N  C   H  + E  Q  +  L V  P
Sbjct: 167 LVSGSR---FL---ITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDP 220

Query: 244 PEVS---ISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQG--AQLL 298
              +   + G+D+   +      L C A  +PEP  Y W     PL      Q     LL
Sbjct: 221 ANSAPSILDGFDHRKAMAGQRVELPCKALGHPEP-DYRWLKDNMPLELSGRFQKTVTGLL 279

Query: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKE 331
           I  +    + + +C V+N  G  +    + VK+
Sbjct: 280 IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQ 312


>gi|166295173 kin of IRRE like [Homo sapiens]
          Length = 757

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 68/286 (23%), Positives = 109/286 (38%), Gaps = 48/286 (16%)

Query: 12  LLVALLVLSWP-PPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHG 70
           LLV +L LS     GT     Q P       G    LPC L      + +   + W + G
Sbjct: 4   LLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVL------LNYSGIVQWTKDG 57

Query: 71  ESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQ 130
            +  M       G       R   V +   A+    +L +    + D+ +Y C       
Sbjct: 58  LALGM-------GQGLKAWPRYRVVGS---ADAGQYNLEITDAELSDDASYECQATEAAL 107

Query: 131 GSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR--------CVSTGGRPPAQITWHSD 182
            SR     L VL  P++T      ++ G PV + +        C +   +P A I W  D
Sbjct: 108 RSRRAK--LTVLIPPEDT------RIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRD 159

Query: 183 LGGMPNTSQVPGFLSGTV--------TVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLL 234
                  +Q  G ++ T         T  S  ++ P+    G+  TC+  +E+    +  
Sbjct: 160 ------GTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSGKET 213

Query: 235 TVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWS 280
           ++ L V++PP V++S        G+     TC A +NPE  GY W+
Sbjct: 214 SIELDVHHPPTVTLSIEPQTVQEGE-RVVFTCQATANPEILGYRWA 258


>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
          Length = 600

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 55/241 (22%), Positives = 99/241 (41%), Gaps = 32/241 (13%)

Query: 108 LRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT---GEPVPMA 164
           L++    ++D+  Y C  +     SR     L VL  P +   +    ++   G+P+ + 
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPAR--LTVLVPPDDPVILGGPVISLRAGDPLNLT 169

Query: 165 RCVSTGGRPPAQITWHSDLGGMPNTSQVPGFL---SGTVTVTSLWILVPSSQVDGKNVTC 221
            C +   +P A I W    G + N +     L       ++ S   + P    +G+++ C
Sbjct: 170 -CHADNAKPAASIIWLRK-GEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVC 227

Query: 222 KVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
           +  +++    +  +V + + +PP V++S  +    L  N  T  C A++NP  T Y W  
Sbjct: 228 RATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRW-- 284

Query: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTT---------LICNVTNALGARQAELTVQVKEG 332
                     A+  Q++     +   TT         + C VTNALG+     TV V  G
Sbjct: 285 ----------AKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFG 334

Query: 333 P 333
           P
Sbjct: 335 P 335



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 1/73 (1%)

Query: 107 SLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARC 166
           +L +  +R ED G Y C  V    G+   ++ L V   P  ++   +  L GE     +C
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEK-GQIKC 440

Query: 167 VSTGGRPPAQITW 179
                 PP +I W
Sbjct: 441 FIRSTPPPDRIAW 453


>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
          Length = 778

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 55/241 (22%), Positives = 99/241 (41%), Gaps = 32/241 (13%)

Query: 108 LRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT---GEPVPMA 164
           L++    ++D+  Y C  +     SR     L VL  P +   +    ++   G+P+ + 
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPAR--LTVLVPPDDPVILGGPVISLRAGDPLNLT 169

Query: 165 RCVSTGGRPPAQITWHSDLGGMPNTSQVPGFL---SGTVTVTSLWILVPSSQVDGKNVTC 221
            C +   +P A I W    G + N +     L       ++ S   + P    +G+++ C
Sbjct: 170 -CHADNAKPAASIIWLRK-GEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVC 227

Query: 222 KVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
           +  +++    +  +V + + +PP V++S  +    L  N  T  C A++NP  T Y W  
Sbjct: 228 RATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRW-- 284

Query: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTT---------LICNVTNALGARQAELTVQVKEG 332
                     A+  Q++     +   TT         + C VTNALG+     TV V  G
Sbjct: 285 ----------AKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFG 334

Query: 333 P 333
           P
Sbjct: 335 P 335



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 1/73 (1%)

Query: 107 SLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARC 166
           +L +  +R ED G Y C  V    G+   ++ L V   P  ++   +  L GE     +C
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEK-GQIKC 440

Query: 167 VSTGGRPPAQITW 179
                 PP +I W
Sbjct: 441 FIRSTPPPDRIAW 453


>gi|90903245 CD200 antigen isoform b [Homo sapiens]
          Length = 294

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 9/153 (5%)

Query: 74  SMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSR 133
           +M  F +  G     + + +    +LG  L+N+++  + + +EDEG Y CLF TF  G  
Sbjct: 99  NMVTFSENHGVVIQPAYKDKINITQLG--LQNSTITFWNITLEDEGCYMCLFNTFGFGKI 156

Query: 134 SVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVP 193
           S    L V  +P     +  +        +    S   RP   + W     G+ N++   
Sbjct: 157 SGTACLTVYVQP-----IVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTL 211

Query: 194 GFLSGTVTVTS-LWILVPSSQVDGKNVTCKVEH 225
              +GT +VTS L I  P +QV GK V C+V H
Sbjct: 212 SHPNGTTSVTSILHIKDPKNQV-GKEVICQVLH 243


>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
          Length = 269

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 9/153 (5%)

Query: 74  SMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSR 133
           +M  F +  G     + + +    +LG  L+N+++  + + +EDEG Y CLF TF  G  
Sbjct: 74  NMVTFSENHGVVIQPAYKDKINITQLG--LQNSTITFWNITLEDEGCYMCLFNTFGFGKI 131

Query: 134 SVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVP 193
           S    L V  +P     +  +        +    S   RP   + W     G+ N++   
Sbjct: 132 SGTACLTVYVQP-----IVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTL 186

Query: 194 GFLSGTVTVTS-LWILVPSSQVDGKNVTCKVEH 225
              +GT +VTS L I  P +QV GK V C+V H
Sbjct: 187 SHPNGTTSVTSILHIKDPKNQV-GKEVICQVLH 218


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 81/334 (24%), Positives = 128/334 (38%), Gaps = 57/334 (17%)

Query: 19   LSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVF 78
            L++P   T  + ++ P+      G ++ L C   VP    +H +Q+TW + G  GS+ V 
Sbjct: 2333 LAYPAGSTQPIRIE-PSSSQVAEGQTLDLNCV--VPGQ--SH-AQVTWHKRG--GSLPVR 2384

Query: 79   HQTQGP-----SYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSR 133
            HQT G        S +   E+V   LG+ +   +  +  + +E  G+   L VT      
Sbjct: 2385 HQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVL--VTIEPAGSVPALGVTPT---- 2438

Query: 134  SVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVP 193
                 +R+ +     AE Q + L         C+   G+  AQ+TWH   G +P   QV 
Sbjct: 2439 -----VRIESSSSQVAEGQTLDLN--------CL-VAGQAHAQVTWHKRGGSLPARHQVH 2484

Query: 194  GFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLT----------VYYP 243
            G     + VT           D     C+V   S  +   + V +           V YP
Sbjct: 2485 GSRLRLLQVTP---------ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYP 2535

Query: 244  PEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVD 303
              +  S          +   L C   S   P    W    G LP      G++L I  V 
Sbjct: 2536 VRIESSSAS---LANGHTLDLNCLVASQA-PHTITWYKRGGSLPSRHQIVGSRLRIPQVT 2591

Query: 304  KPINTTLICNVTNALGARQAELTVQVKEGPPSEH 337
               +   +C+V+N  G+R+  L V + +G  S H
Sbjct: 2592 PADSGEYVCHVSNGAGSRETSLIVTI-QGSGSSH 2624



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 64/291 (21%), Positives = 102/291 (35%), Gaps = 49/291 (16%)

Query: 62   SQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNY 121
            +Q+TW + G  GS+   HQ +G                      + L +F     D G Y
Sbjct: 2274 AQVTWYKRG--GSLPARHQVRG----------------------SRLYIFQASPADAGQY 2309

Query: 122  TCLFVTFPQGSRSVDIWLRV---LAKPQNTAEVQKVQLTGEPVPMARCVSTG----GRPP 174
             C      + S +V +       LA P  + +  +++ +   V   + +       G+  
Sbjct: 2310 VCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSH 2369

Query: 175  AQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHES--FEKPQ 232
            AQ+TWH   G +P   Q  G         SL  L  +S  D     C+V   S   E   
Sbjct: 2370 AQVTWHKRGGSLPVRHQTHG---------SLLRLYQASPADSGEYVCRVLGSSVPLEASV 2420

Query: 233  LLTVNLTVYYP-----PEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLP 287
            L+T+      P     P V I    +    GQ    L C            W    G LP
Sbjct: 2421 LVTIEPAGSVPALGVTPTVRIESSSSQVAEGQT-LDLNCLVAGQAHAQ-VTWHKRGGSLP 2478

Query: 288  PFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHS 338
                  G++L +  V    +   +C V  + G ++A + V +++     HS
Sbjct: 2479 ARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHS 2529



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 70/293 (23%), Positives = 109/293 (37%), Gaps = 49/293 (16%)

Query: 62   SQLTWARHGESGSMAVFHQTQGPSY-----SESKRLEFVAARLGAELRNASLRMFGLRVE 116
            +Q+TW + G  GS+   HQT+G        S +   E+V   +G+   +  L    L   
Sbjct: 2756 AQVTWHKRG--GSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGS---SGPLEASVLVTI 2810

Query: 117  DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQ 176
            +    + + V  P G+  +    R+       AE Q + L        +CV   G+  AQ
Sbjct: 2811 EASGSSAVHVPAPGGAPPI----RIEPSSSRVAEGQTLDL--------KCV-VPGQAHAQ 2857

Query: 177  ITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTV 236
            +TWH   G +P   QV G          L  L   S  D    +C+V   S      + V
Sbjct: 2858 VTWHKRGGNLPARHQVHG---------PLLRLNQVSPADSGEYSCQVTGSSGTLEASVLV 2908

Query: 237  NLTVYYPPEVSISGYDNNWYLGQNEATLT----------CDARSNPEPTGYNWSTTMGPL 286
             +    P  +   G     Y+  + + +T             +++ + T   W    G L
Sbjct: 2909 TIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVT---WYKRGGSL 2965

Query: 287  PPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQ-AELTVQVKEGPPSEHS 338
            P      G+QL +  V    +   +C   +  G  Q A  TV V   PPSE S
Sbjct: 2966 PARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTV---PPSEGS 3015



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 57/247 (23%), Positives = 95/247 (38%), Gaps = 20/247 (8%)

Query: 101  AELRNASLRMFGLRVEDEGNYTCLFVTFP--QGSRSVDIWLRVLAKPQNTAEVQKVQLTG 158
            A++    LR+  +   D+  Y C   +    Q +R+V + +     P+     ++ Q+  
Sbjct: 1911 AQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAV-LHVHGGGGPRVQVSPERTQVHA 1969

Query: 159  EPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPS-SQVDGK 217
                   C    G P A ITW  + G +P     P   S    + +L  L+P+ +  D  
Sbjct: 1970 GRTVRLYC-RAAGVPSATITWRKEGGSLP-----PQARSERTDIATL--LIPAITTADAG 2021

Query: 218  NVTCKVEHESFE---KPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEP 274
               C     +     + Q++ ++ +   PP V I     +   GQ    L C    +   
Sbjct: 2022 FYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQT-LDLNCVVAGSAHA 2080

Query: 275  TGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPP 334
                W    G LPP     G++L +  V    +   +C V N  G ++A +TV V  G  
Sbjct: 2081 Q-VTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHG-- 2137

Query: 335  SEHSGIS 341
              HSG S
Sbjct: 2138 -THSGPS 2143



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 7/92 (7%)

Query: 262  ATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGAR 321
            ATL C A  +P PT  +WS    PLP     +G  L+I  V +  +   ICN T+  G  
Sbjct: 3229 ATLRCSATGSPAPT-IHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHA 3287

Query: 322  QAELTVQVKEGPP-----SEHSGISRNAIIFL 348
            +A + + V E PP      EH+ +     + L
Sbjct: 3288 EATIILHV-ESPPYATTVPEHASVQAGETVQL 3318



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 67/300 (22%), Positives = 105/300 (35%), Gaps = 74/300 (24%)

Query: 64   LTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTC 123
            +TW + G  GS+   HQT G                      + LR+  + V D G Y C
Sbjct: 2661 ITWYKRG--GSLPSRHQTHG----------------------SHLRLHQMSVADSGEYVC 2696

Query: 124  --------------LFVTFPQGSRSV---DIWLRVLAKPQNTAEVQKVQLTGEPVPMARC 166
                          + V+   GS S     + +R+ +   + AE + + L         C
Sbjct: 2697 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLN--------C 2748

Query: 167  VSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHE 226
            V   G+  AQ+TWH   G +P+  Q  G         S   L   S  D     C+V   
Sbjct: 2749 V-VPGQAHAQVTWHKRGGSLPSHHQTRG---------SRLRLHHVSPADSGEYVCRVMGS 2798

Query: 227  S--FEKPQLLTVNLT----VYYP-----PEVSISGYDNNWYLGQN-EATLTCDARSNPEP 274
            S   E   L+T+  +    V+ P     P + I    +    GQ  +       +++ + 
Sbjct: 2799 SGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2858

Query: 275  TGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPP 334
            T   W    G LP      G  L +  V    +    C VT + G  +A + V ++   P
Sbjct: 2859 T---WHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSP 2915



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 70/279 (25%), Positives = 103/279 (36%), Gaps = 44/279 (15%)

Query: 62   SQLTWARHGESGSMAVFHQTQG-----PSYSESKRLEFVA-ARLGAELRNASLRMFGLRV 115
            +Q+TW R G  GS+    Q  G     P  S +   E+V     G+  + AS+ +  L  
Sbjct: 2080 AQVTWYRRG--GSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHG 2137

Query: 116  EDEG-NYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPP 174
               G +YT +    P  +R +    R+     + AE Q + L         CV   G+  
Sbjct: 2138 THSGPSYTPV----PGSTRPI----RIEPSSSHVAEGQTLDLN--------CV-VPGQAH 2180

Query: 175  AQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHES--FEKPQ 232
            AQ+TWH   G +P   Q  G         SL  L   +  D     C V   S   E   
Sbjct: 2181 AQVTWHKRGGSLPARHQTHG---------SLLRLHQVTPADSGEYVCHVVGTSGPLEASV 2231

Query: 233  LLTVNLTVYYP--PEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFA 290
            L+T+  +V     P V I    +    GQ    L+C            W    G LP   
Sbjct: 2232 LVTIEASVIPGPIPPVRIESSSSTVAEGQT-LDLSCVVAGQAH-AQVTWYKRGGSLPARH 2289

Query: 291  VAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQV 329
              +G++L I           +C  +N +   +A +TV V
Sbjct: 2290 QVRGSRLYIFQASPADAGQYVCRASNGM---EASITVTV 2325



 Score = 37.0 bits (84), Expect = 0.033
 Identities = 58/291 (19%), Positives = 103/291 (35%), Gaps = 59/291 (20%)

Query: 62   SQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNY 121
            +Q+TW + G  GS+   HQT G                      + LR+  +   D G Y
Sbjct: 2954 AQVTWYKRG--GSLPARHQTHG----------------------SQLRLHLVSPADSGEY 2989

Query: 122  TCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMA---------RCVSTGGR 172
             C   + P   +     + V     ++  ++   ++ +P             +C+   G 
Sbjct: 2990 VCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGA 3049

Query: 173  PPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQ 232
             P  + W +    + +   +    +G++      I +  ++         V   ++   Q
Sbjct: 3050 APISLEWKTRNQELEDNVHISP--NGSI------ITIVGTRPSNHGTYRCVASNAYGVAQ 3101

Query: 233  LLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWS-----------T 281
             + VNL+V+ PP VS+      W       TL C +   P  +   W+            
Sbjct: 3102 SV-VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSA-RWTRISSTPAKLEQR 3159

Query: 282  TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEG 332
            T G +   AV Q +    +P D     T +C   NALG  Q ++ V V  G
Sbjct: 3160 TYGLMDSHAVLQISS--AKPSDA---GTYVCLAQNALGTAQKQVEVIVDTG 3205



 Score = 35.8 bits (81), Expect = 0.074
 Identities = 56/239 (23%), Positives = 87/239 (36%), Gaps = 28/239 (11%)

Query: 100  GAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQ---KVQL 156
            G  +++  LR+  L    +G Y C     P G       L + A P     ++   +  +
Sbjct: 3443 GHSVQDGVLRIQNLDQSCQGTYICQ-AHGPWGKAQASAQLVIQALPSVLINIRTSVQTVV 3501

Query: 157  TGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDG 216
             G  V    C++ G  P  Q+TW S +GG      V     G V +  + +       D 
Sbjct: 3502 VGHAVEF-ECLALGD-PKPQVTW-SKVGGHLRPGIVQS--GGVVRIAHVEL------ADA 3550

Query: 217  KNVTCKVEHES--FEKPQLLTVNLT--VYYPPEVSISGYDNNWYLGQNEATLTCDARSNP 272
                C   + +   +   LL V     +  P EV +           + A   C A   P
Sbjct: 3551 GQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPA--------GSAAVFPCIASGYP 3602

Query: 273  EPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKE 331
             P   +WS   G LPP +  +   L++  V      T +C  TN  G  +A   +QV E
Sbjct: 3603 TPD-ISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPE 3660



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 1/68 (1%)

Query: 266  CDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAEL 325
            C A  +P+P    WS   G L P  V  G  + I  V+        C  TNA G  Q+ +
Sbjct: 3510 CLALGDPKPQ-VTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHV 3568

Query: 326  TVQVKEGP 333
             + V+  P
Sbjct: 3569 LLLVQALP 3576


>gi|67188443 CD276 antigen isoform a [Homo sapiens]
          Length = 534

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 53/172 (30%), Positives = 75/172 (43%), Gaps = 12/172 (6%)

Query: 26  TGDVVVQAPTQ-VPGFLGDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQ--T 81
           TG V VQ P   V   +G   TL C +   P   +  ++ L W        +  F +   
Sbjct: 244 TGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLN-LIWQLTDTKQLVHSFTEGRD 302

Query: 82  QGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRV 141
           QG +Y+    L       G    NASLR+  +RV DEG++TC       GS +V + +  
Sbjct: 303 QGSAYANRTALFPDLLAQG----NASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAA 358

Query: 142 -LAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQV 192
             +KP  T E  K    G+ V +  C S  G P A++ W  D  G+P T  V
Sbjct: 359 PYSKPSMTLEPNKDLRPGDTVTIT-CSSYRGYPEAEVFW-QDGQGVPLTGNV 408



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 53/172 (30%), Positives = 75/172 (43%), Gaps = 12/172 (6%)

Query: 26  TGDVVVQAPTQ-VPGFLGDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFH--QT 81
           TG + VQ P   V   +G   TL C +   P   +  ++ L W        +  F   Q 
Sbjct: 26  TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLN-LIWQLTDTKQLVHSFAEGQD 84

Query: 82  QGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRV 141
           QG +Y+    L       G    NASLR+  +RV DEG++TC       GS +V + +  
Sbjct: 85  QGSAYANRTALFPDLLAQG----NASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAA 140

Query: 142 -LAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQV 192
             +KP  T E  K    G+ V +  C S  G P A++ W  D  G+P T  V
Sbjct: 141 PYSKPSMTLEPNKDLRPGDTVTIT-CSSYQGYPEAEVFW-QDGQGVPLTGNV 190


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,922,104
Number of Sequences: 37866
Number of extensions: 849097
Number of successful extensions: 3372
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 224
Number of HSP's that attempted gapping in prelim test: 2739
Number of HSP's gapped (non-prelim): 712
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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