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Search of human proteins with 205360983
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205360983 potassium channel, subfamily K, member 16 isoform
3 [Homo sapiens]
(294 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 602 e-173
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 556 e-158
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 454 e-128
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 454 e-128
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 228 5e-60
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 199 2e-51
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 199 2e-51
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 199 2e-51
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 194 8e-50
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 194 8e-50
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 194 8e-50
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 194 8e-50
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 192 4e-49
gi|15718767 TRAAK [Homo sapiens] 185 5e-47
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 155 3e-38
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 154 9e-38
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 135 3e-32
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 131 8e-31
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 130 1e-30
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 112 5e-25
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 108 6e-24
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 108 6e-24
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 108 7e-24
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 107 1e-23
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 105 5e-23
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 63 3e-10
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 42 8e-04
gi|27437001 potassium voltage-gated channel, subfamily H, member... 42 8e-04
gi|22024390 potassium voltage-gated channel, subfamily H, member... 40 0.002
gi|27886648 potassium voltage-gated channel, subfamily H, member... 40 0.002
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 602 bits (1553), Expect = e-173
Identities = 294/294 (100%), Positives = 294/294 (100%)
Query: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
Query: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240
LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240
Query: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPRPQKIPISA 294
LLGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPRPQKIPISA
Sbjct: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPRPQKIPISA 294
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 556 bits (1432), Expect = e-158
Identities = 279/305 (91%), Positives = 280/305 (91%), Gaps = 14/305 (4%)
Query: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
Query: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240
LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240
Query: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPR------------PQ 288
LLGLAWLALILPLGPLLLHRCCQLWLLS G GA + P PR PQ
Sbjct: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGC--GAKAAPGRRPRRGSTAARGVQVTPQ 298
Query: 289 KIPIS 293
PIS
Sbjct: 299 DFPIS 303
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 454 bits (1167), Expect = e-128
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
Query: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
Score = 30.4 bits (67), Expect = 1.9
Identities = 12/39 (30%), Positives = 20/39 (51%)
Query: 197 WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSL 235
W F F+FA ++TIG+G+ T+ + + Y L
Sbjct: 93 WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 454 bits (1167), Expect = e-128
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
Query: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
Score = 30.4 bits (67), Expect = 1.9
Identities = 12/39 (30%), Positives = 20/39 (51%)
Query: 197 WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSL 235
W F F+FA ++TIG+G+ T+ + + Y L
Sbjct: 93 WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 228 bits (581), Expect = 5e-60
Identities = 112/259 (43%), Positives = 169/259 (65%), Gaps = 13/259 (5%)
Query: 2 PSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL 61
P + C + LLLAY+ YL LG +F LE +A S FQ +K L+N+TCL
Sbjct: 10 PEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCL 69
Query: 62 DQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAG 121
D+ A++ ++ +++A+ G + N+T+ W+ SFFF+ + +TTIGYGNL+P+T A
Sbjct: 70 DRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAA 129
Query: 122 QVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDR-------PRRSQVLQVLGLAL 174
++FC+F+AL+GIPLN++ LN LG ++ + W R P +++ L G
Sbjct: 130 RLFCIFFALVGIPLNLVVLNRLGHLMQ---QGVNHWASRLGGTWQDPDKARWLAGSGA-- 184
Query: 175 FLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRS 234
L G L+ L+ PP++FSH+EGWS++EGFYFAFITLST+GFGDYV+G +PS+ Y Y++
Sbjct: 185 -LLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKN 243
Query: 235 LAAIWILLGLAWLALILPL 253
+ ++WIL G+AWLALI+ L
Sbjct: 244 MVSLWILFGMAWLALIIKL 262
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 199 bits (506), Expect = 2e-51
Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)
Query: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
V+ + + V YL+ G +F+ LE+ E+ ++ LEK FL ++ C+ +E +Q
Sbjct: 77 VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 136
Query: 74 MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
++A GV+P GNS+N S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 137 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 196
Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
IPL L + LGT +A +E+ + + SQ ++V+ LF+ G +V + P
Sbjct: 197 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 256
Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
++F ++EGW+ E YF +TL+T+GFGD+V G + +Y Y+ L WIL+GLA+
Sbjct: 257 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 316
Query: 248 ALILPL 253
A +L +
Sbjct: 317 AAVLSM 322
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 199 bits (506), Expect = 2e-51
Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)
Query: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
V+ + + V YL+ G +F+ LE+ E+ ++ LEK FL ++ C+ +E +Q
Sbjct: 77 VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 136
Query: 74 MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
++A GV+P GNS+N S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 137 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 196
Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
IPL L + LGT +A +E+ + + SQ ++V+ LF+ G +V + P
Sbjct: 197 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 256
Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
++F ++EGW+ E YF +TL+T+GFGD+V G + +Y Y+ L WIL+GLA+
Sbjct: 257 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 316
Query: 248 ALILPL 253
A +L +
Sbjct: 317 AAVLSM 322
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 199 bits (506), Expect = 2e-51
Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)
Query: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
V+ + + V YL+ G +F+ LE+ E+ ++ LEK FL ++ C+ +E +Q
Sbjct: 72 VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 131
Query: 74 MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
++A GV+P GNS+N S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 132 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191
Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
IPL L + LGT +A +E+ + + SQ ++V+ LF+ G +V + P
Sbjct: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 251
Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
++F ++EGW+ E YF +TL+T+GFGD+V G + +Y Y+ L WIL+GLA+
Sbjct: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 311
Query: 248 ALILPL 253
A +L +
Sbjct: 312 AAVLSM 317
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 194 bits (493), Expect = 8e-50
Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)
Query: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
V + L V YL++GAT+F+ LE+ E R ++K F+ ++C++ +++ +Q I
Sbjct: 47 VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 106
Query: 74 MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
+ A G+ P GN++N S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 107 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 166
Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
IPL L + LGT +A +E + SQ ++++ +F+ G ++ + P
Sbjct: 167 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 226
Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
++F H+EGWS + YF ITL+TIGFGDYV G + Y+ Y+ + WIL+GLA+
Sbjct: 227 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 285
Query: 248 ALILPL 253
A +L +
Sbjct: 286 AAVLSM 291
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 194 bits (493), Expect = 8e-50
Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)
Query: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
V + L V YL++GAT+F+ LE+ E R ++K F+ ++C++ +++ +Q I
Sbjct: 62 VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 121
Query: 74 MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
+ A G+ P GN++N S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 122 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 181
Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
IPL L + LGT +A +E + SQ ++++ +F+ G ++ + P
Sbjct: 182 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 241
Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
++F H+EGWS + YF ITL+TIGFGDYV G + Y+ Y+ + WIL+GLA+
Sbjct: 242 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 300
Query: 248 ALILPL 253
A +L +
Sbjct: 301 AAVLSM 306
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 194 bits (493), Expect = 8e-50
Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)
Query: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
V + L V YL++GAT+F+ LE+ E R ++K F+ ++C++ +++ +Q I
Sbjct: 58 VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 117
Query: 74 MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
+ A G+ P GN++N S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 118 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 177
Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
IPL L + LGT +A +E + SQ ++++ +F+ G ++ + P
Sbjct: 178 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 237
Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
++F H+EGWS + YF ITL+TIGFGDYV G + Y+ Y+ + WIL+GLA+
Sbjct: 238 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 296
Query: 248 ALILPL 253
A +L +
Sbjct: 297 AAVLSM 302
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 194 bits (493), Expect = 8e-50
Identities = 97/238 (40%), Positives = 152/238 (63%), Gaps = 3/238 (1%)
Query: 16 PLLL-AYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIM 74
PLL A + YL +GA IF++LE +++ + +KL L+ + CL Q +++ ++V+
Sbjct: 6 PLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVS 65
Query: 75 EAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
+A +GV GN T +NW++ ++ FA TV+TTIGYGN+AP T AG++FCVFY L G+P
Sbjct: 66 DAAGQGVAITGNQTF-NNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124
Query: 135 LNVIFLNHLGTGLRAHLAAIERWEDRPRRS-QVLQVLGLALFLTLGTLVILIFPPMVFSH 193
L + +++ LG + ++ + S + Q+ +F+ G LV L+ PP VF
Sbjct: 125 LCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMV 184
Query: 194 VEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
EGW++ EG Y++FIT+STIGFGD+V G +PS +Y ++YR +WI LGLAWL+L +
Sbjct: 185 TEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFV 242
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 192 bits (487), Expect = 4e-49
Identities = 96/228 (42%), Positives = 145/228 (63%), Gaps = 13/228 (5%)
Query: 2 PSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL 61
P + C + LLLAY+ YL LG +F LE +A S FQ +K L+N+TCL
Sbjct: 10 PEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCL 69
Query: 62 DQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAG 121
D+ A++ ++ +++A+ G + N+T+ W+ SFFF+ + +TTIGYGNL+P+T A
Sbjct: 70 DRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAA 129
Query: 122 QVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDR-------PRRSQVLQVLGLAL 174
++FC+F+AL+GIPLN++ LN LG ++ + W R P +++ L G
Sbjct: 130 RLFCIFFALVGIPLNLVVLNRLGHLMQ---QGVNHWASRLGGTWQDPDKARWLAGSGA-- 184
Query: 175 FLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGT 222
L G L+ L+ PP++FSH+EGWS++EGFYFAFITLST+GFGDYV+ +
Sbjct: 185 -LLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIAS 231
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 185 bits (469), Expect = 5e-47
Identities = 101/249 (40%), Positives = 154/249 (61%), Gaps = 15/249 (6%)
Query: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
+L LL + YL+ GA +F+ LE+ E Q++ + + +FL + C+ + ++ +
Sbjct: 6 LLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEV 65
Query: 74 MEAWVKGVNPKGNSTNPSN---WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYAL 130
+A G +P+ NST+ S+ WD GS+FFF+GT++TTIGYGN+A T+AG++FC+FYAL
Sbjct: 66 ADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYAL 125
Query: 131 LGIPLNVIFL----NHLGTGLRAHLAAIE----RWEDRPRRSQVLQVLGLALFLTLGTLV 182
+GIPL I L + LG+ LR + IE +W P ++++VL LFL +G L+
Sbjct: 126 VGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPP---ELVRVLSAMLFLLIGCLL 182
Query: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILL 242
++ P VF ++E WS E YF +TL+T+GFGDYV G DP + Y+ L WILL
Sbjct: 183 FVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADP-RQDSPAYQPLVWFWILL 241
Query: 243 GLAWLALIL 251
GLA+ A +L
Sbjct: 242 GLAYFASVL 250
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 155 bits (393), Expect = 3e-38
Identities = 86/239 (35%), Positives = 136/239 (56%), Gaps = 4/239 (1%)
Query: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEA 76
L+L Y+ YL+ GA +F +E E R + + K RFLE + CL + +EQF+ ++EA
Sbjct: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
Query: 77 WVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLN 136
GV+ N++ NWDF S+ FFA TV++T GYG+ P ++ G+ FC+ Y+++GIP
Sbjct: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
Query: 137 VIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF---PPMVFSH 193
++FL + + H+ R QV+ + + LG + + F P VFS
Sbjct: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205
Query: 194 VE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
+E W+F E FYF FI+LSTIG GDYV G ++ + +Y+ ++LLGL + ++L
Sbjct: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 154 bits (389), Expect = 9e-38
Identities = 90/255 (35%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Query: 11 GGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFV 70
G + L AY YL+LGA + LE EA+ R + + + + L+ C+ A++ FV
Sbjct: 4 GALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFV 63
Query: 71 QVIMEAWVKGVNPKGNSTNPSN-----WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
+ ++ A G N++ +N WDF S+ FFA T++TT+GYG P T+AG+ F
Sbjct: 64 ERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFS 123
Query: 126 VFYALLGIPLNVIFLNHLGTGLRAHLAAIE------RWEDRPRRSQVLQVLGLALFLTLG 179
+ +ALLG+P ++ L L L + RW PRR+ ++ L LG
Sbjct: 124 IAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL-----LG 178
Query: 180 TLVILIF--PPMVFSHVE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLA 236
+V + F P ++F+H+E WSF + FYF FI+LSTIG GDYV G P + Y ++Y+ L
Sbjct: 179 VVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLV 238
Query: 237 AIWILLGLAWLALIL 251
+++ LGL + L+L
Sbjct: 239 TVYLFLGLVAMVLVL 253
Score = 28.1 bits (61), Expect = 9.6
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 197 WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPL 256
W F+ +FA ++T+G+G TD K + + L +L L A L L L
Sbjct: 91 WDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSL--L 148
Query: 257 LLH 259
L H
Sbjct: 149 LTH 151
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 135 bits (341), Expect = 3e-32
Identities = 90/248 (36%), Positives = 126/248 (50%), Gaps = 20/248 (8%)
Query: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
R L L++ YLL+GA +F LE + E R + +L + Y L Q E+ +V
Sbjct: 7 RTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERV 65
Query: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
++ + P W F SF+FA TV+TTIGYG+ APST+ G+VFC+FYALLG
Sbjct: 66 VLR-----LKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLG 117
Query: 133 IPLNVIFLNHLGTGLRA------HLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
IPL ++ LG + H A R S VL + F + TL I
Sbjct: 118 IPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVL-IGFFSCISTLCI--- 173
Query: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
FSH E W+F + +Y+ FITL+TIGFGDYV + D + Y + + ++IL GL
Sbjct: 174 GAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLT 233
Query: 246 WLALILPL 253
+ L L
Sbjct: 234 VIGAFLNL 241
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 131 bits (329), Expect = 8e-31
Identities = 87/248 (35%), Positives = 130/248 (52%), Gaps = 20/248 (8%)
Query: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQ-WAMEQFVQ 71
R L L++ YLL+GA +F LE E + ++ + E++R Y + + + V
Sbjct: 7 RTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI 66
Query: 72 VIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
+ E GV W F SF+FA TV+TTIGYG+ AP T+AG+ FC+FYA+L
Sbjct: 67 LQSEPHRAGVQ----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
Query: 132 GIPLNVIFLNHLG----TGLRAHLAAIER-WEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
GIPL ++ LG T +R L I++ R + ++ + F +GTL I
Sbjct: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCI--- 173
Query: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
FS E WSF +Y+ FITL+TIGFGDYV + T + +Y + + ++IL+GL
Sbjct: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233
Query: 246 WLALILPL 253
+ L L
Sbjct: 234 VIGAFLNL 241
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 130 bits (328), Expect = 1e-30
Identities = 98/292 (33%), Positives = 142/292 (48%), Gaps = 38/292 (13%)
Query: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
R L+L +CYLL+GA +F LE +AE+ R + ++K L + ++
Sbjct: 7 RAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDYRELERL 65
Query: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
++A + W F SF+FA TV+TTIGYG+ AP T++G+VFC+FYALLG
Sbjct: 66 ALQAEPHRAGRQ--------WKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLG 117
Query: 133 IPLNVIFLNHLGTGLRAHLAAI---------ERWEDRPRRSQVLQ-VLGLALFLTLGTLV 182
IPL ++ LG L A + + RW + V+ +L A L LG
Sbjct: 118 IPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGA-- 175
Query: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWIL 241
+ FSH EGW+F +Y+ FITL+TIGFGD+V + + + Y + + ++IL
Sbjct: 176 ------VAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYIL 229
Query: 242 LGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPRPQKIPIS 293
LGL + L L L W + AA PS PRP P S
Sbjct: 230 LGLTVIGAFLNLVVLRFLVASADW--------PERAARPPS--PRPPGAPES 271
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 112 bits (279), Expect = 5e-25
Identities = 81/244 (33%), Positives = 126/244 (51%), Gaps = 14/244 (5%)
Query: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
L++A++ L LGA +FQ LE + + + + E F E+ CL A+E+ + +
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 76 AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
GV+ GNS+ WD S+ FA +++TT GYG++AP + G+ FC+ YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
+ V L H L R W+ P R+ +LQ + L L L + V+L P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAI--WILLGLAWL 247
++G S YF F +LSTIG D + G S H + + A+ ++LLGL L
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGYLLLGL--L 247
Query: 248 ALIL 251
A++L
Sbjct: 248 AMLL 251
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 108 bits (270), Expect = 6e-24
Identities = 78/241 (32%), Positives = 119/241 (49%), Gaps = 14/241 (5%)
Query: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
L++A++ L LGA +FQ LE + + + + E F E+ CL A+E+ + +
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 76 AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
GV+ GNS+ WD S+ FA +++TT GYG++AP + G+ FC+ YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
+ V L H L R W+ P R+ +LQ + L L L + V+L P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAI----WILLGLA 245
++G S YF F +LSTIG D + G S H + + A+ L G A
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGGGTSLQGTA 249
Query: 246 W 246
W
Sbjct: 250 W 250
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 108 bits (270), Expect = 6e-24
Identities = 78/241 (32%), Positives = 119/241 (49%), Gaps = 14/241 (5%)
Query: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
L++A++ L LGA +FQ LE + + + + E F E+ CL A+E+ + +
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 76 AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
GV+ GNS+ WD S+ FA +++TT GYG++AP + G+ FC+ YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
+ V L H L R W+ P R+ +LQ + L L L + V+L P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAI----WILLGLA 245
++G S YF F +LSTIG D + G S H + + A+ L G A
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGGGTSLQGTA 249
Query: 246 W 246
W
Sbjct: 250 W 250
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 108 bits (269), Expect = 7e-24
Identities = 80/282 (28%), Positives = 136/282 (48%), Gaps = 32/282 (11%)
Query: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
R L L V YLL GA +F LE E Q++ +++ F + L + + F++
Sbjct: 19 RFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRH 77
Query: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
EA G+ + ++ P WDF +F+F GTVV+TIG+G P+T G++F +FY L+G
Sbjct: 78 YEEATRAGI--RVDNVRP-RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134
Query: 133 IPLNVIFLNHLGTGL---------RAHLAAIERWEDRPRRS-------QVLQVLG----- 171
++F N L H + R P+ S +V + G
Sbjct: 135 CSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSV 194
Query: 172 --LALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYI 229
+ L L +++I +++ +EGWS+ + YF F+ STIGFGD V + + HY
Sbjct: 195 YYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV--SSQNAHYE 252
Query: 230 S--VYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSR 269
S +YR ++IL+G+ + + + +L+ + W+L +
Sbjct: 253 SQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLN-WILRK 293
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 107 bits (267), Expect = 1e-23
Identities = 73/218 (33%), Positives = 111/218 (50%), Gaps = 10/218 (4%)
Query: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
L++A++ L LGA +FQ LE + + + + E F E+ CL A+E+ + +
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 76 AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
GV+ GNS+ WD S+ FA +++TT GYG++AP + G+ FC+ YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
+ V L H L R W+ P R+ +LQ + L L L + V+L P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189
Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKH 227
++G S YF F +LSTIG D + G S H
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLH 227
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 105 bits (262), Expect = 5e-23
Identities = 84/298 (28%), Positives = 135/298 (45%), Gaps = 35/298 (11%)
Query: 2 PSAGLCSCWG-------GRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF 54
PS C C GR + L YL+ GAT+F LE EA++R ++ F
Sbjct: 20 PSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNF 79
Query: 55 LENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNL 114
+ + + F++ A GV + ++ P WDF +F+F GTVV+TIG+G
Sbjct: 80 SAAHGVAEP-ELRAFLRHYEAALAAGV--RADALRP-RWDFPGAFYFVGTVVSTIGFGMT 135
Query: 115 APSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIER--WEDRPRRSQVL----- 167
P+T G+ F + Y L G ++F N + + LA I R E + RRS +L
Sbjct: 136 TPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFR 195
Query: 168 ----------------QVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLS 211
V + L L L +++ +++ VEGW + + YF F+T S
Sbjct: 196 RGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFS 255
Query: 212 TIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSR 269
TIGFGD V + +YR ++ILLG+ + + + +L+ + W+L +
Sbjct: 256 TIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLN-WMLRK 312
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 63.2 bits (152), Expect = 3e-10
Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 10/139 (7%)
Query: 12 GRVLP---LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL---DQWA 65
G++ P L V Y L+GA +F +E + D + EK FLE + +
Sbjct: 18 GKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETV 75
Query: 66 MEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
+E Q + + ++ V P+ + ++W F SS FF TV +T+GYG + P T G+ C
Sbjct: 76 VEDRKQDL-QGHLQKVKPQWFNRT-THWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLC 133
Query: 126 VFYALLGIPLNVIFLNHLG 144
+ YAL GIPL + L G
Sbjct: 134 MLYALFGIPLMFLVLTDTG 152
Score = 36.6 bits (83), Expect = 0.027
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 168 QVLGLALFLTLGTLVILIFPPMVFSHVEGWS----FSEGFYFAFITLSTIGFGDYVVGTD 223
QV L + L + L++ + + + W F FYF F+TL+TIGFGD V+
Sbjct: 275 QVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHP 334
Query: 224 PSKHYISVY 232
+ S+Y
Sbjct: 335 NFFLFFSIY 343
Score = 29.6 bits (65), Expect = 3.3
Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
P F+ WSF +F ST+G+G T K+ L ++ L G+ +
Sbjct: 92 PQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKY-------LCMLYALFGIPLM 144
Query: 248 ALIL 251
L+L
Sbjct: 145 FLVL 148
Score = 28.1 bits (61), Expect = 9.6
Identities = 13/47 (27%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 94 DFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFL 140
DF ++F+F +TTIG+G+ E F F + + + ++F+
Sbjct: 309 DFENAFYFCFVTLTTIGFGDTV--LEHPNFFLFFSIYIIVGMEIVFI 353
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 41.6 bits (96), Expect = 8e-04
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 86 NSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNV 137
N + W+ G SS +F T +T++G+GN+APST+ ++F V ++G L
Sbjct: 406 NGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYA 465
Query: 138 IFLNHLGTGLRAHLAAIERWED 159
++ T + A R+ +
Sbjct: 466 TIFGNVTTIFQQMYANTNRYHE 487
>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
isoform 1 [Homo sapiens]
Length = 989
Score = 41.6 bits (96), Expect = 8e-04
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 86 NSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNV 137
N + W+ G SS +F T +T++G+GN+APST+ ++F V ++G L
Sbjct: 433 NGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYA 492
Query: 138 IFLNHLGTGLRAHLAAIERWED 159
++ T + A R+ +
Sbjct: 493 TIFGNVTTIFQQMYANTNRYHE 514
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 40.4 bits (93), Expect = 0.002
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 8/85 (9%)
Query: 83 PKGNSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
P +T+ W+ G SS +F T +TTIG+GN+AP+T+ ++F V ++G
Sbjct: 399 PYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSL 458
Query: 135 LNVIFLNHLGTGLRAHLAAIERWED 159
L ++ T + A R+ +
Sbjct: 459 LYATIFGNVTTIFQQMYANTNRYHE 483
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 40.4 bits (93), Expect = 0.002
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 8/85 (9%)
Query: 83 PKGNSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
P +T+ W+ G SS +F T +TTIG+GN+AP+T+ ++F V ++G
Sbjct: 341 PYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSL 400
Query: 135 LNVIFLNHLGTGLRAHLAAIERWED 159
L ++ T + A R+ +
Sbjct: 401 LYATIFGNVTTIFQQMYANTNRYHE 425
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.142 0.462
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,769,670
Number of Sequences: 37866
Number of extensions: 513105
Number of successful extensions: 1767
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1497
Number of HSP's gapped (non-prelim): 189
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.