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Search of human proteins with 19923193
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923193 heat shock 70kD protein binding protein [Homo
sapiens]
(369 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens] 741 0.0
gi|239754359 PREDICTED: similar to heat shock 70kD protein bindi... 201 7e-52
gi|239748906 PREDICTED: hypothetical protein XP_002346852 [Homo ... 201 7e-52
gi|239742930 PREDICTED: hypothetical protein XP_002342689 [Homo ... 201 7e-52
gi|239753617 PREDICTED: similar to heat shock 70kD protein bindi... 108 1e-23
gi|27262638 sperm associated antigen 1 [Homo sapiens] 75 9e-14
gi|27262636 sperm associated antigen 1 [Homo sapiens] 75 9e-14
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 62 6e-10
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 60 4e-09
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 57 2e-08
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 57 2e-08
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 57 3e-08
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 57 3e-08
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 55 1e-07
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 54 2e-07
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 54 2e-07
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 53 4e-07
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 53 4e-07
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 52 7e-07
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 51 2e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 49 6e-06
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 49 9e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 47 3e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 47 3e-05
gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 45 1e-04
gi|62244004 modulator of estrogen induced transcription isoform ... 45 1e-04
gi|63176611 modulator of estrogen induced transcription isoform ... 45 1e-04
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 44 2e-04
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 44 2e-04
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 44 2e-04
>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
Length = 369
Score = 741 bits (1914), Expect = 0.0
Identities = 369/369 (100%), Positives = 369/369 (100%)
Query: 1 MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1 MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
Query: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVA 120
DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVA
Sbjct: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVA 120
Query: 121 AIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPD 180
AIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPD
Sbjct: 121 AIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPD 180
Query: 181 SAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYER 240
SAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYER
Sbjct: 181 SAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYER 240
Query: 241 KREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNFPGGMPGM 300
KREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNFPGGMPGM
Sbjct: 241 KREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNFPGGMPGM 300
Query: 301 GGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISK 360
GGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISK
Sbjct: 301 GGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISK 360
Query: 361 LSAKFGGQA 369
LSAKFGGQA
Sbjct: 361 LSAKFGGQA 369
>gi|239754359 PREDICTED: similar to heat shock 70kD protein binding
protein [Homo sapiens]
Length = 204
Score = 201 bits (512), Expect = 7e-52
Identities = 98/101 (97%), Positives = 99/101 (98%)
Query: 1 MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
MD RKVNELRAFVKMCKQDPS+LHTEEM FLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1 MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
Query: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD
Sbjct: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
>gi|239748906 PREDICTED: hypothetical protein XP_002346852 [Homo
sapiens]
Length = 204
Score = 201 bits (512), Expect = 7e-52
Identities = 98/101 (97%), Positives = 99/101 (98%)
Query: 1 MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
MD RKVNELRAFVKMCKQDPS+LHTEEM FLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1 MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
Query: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD
Sbjct: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
>gi|239742930 PREDICTED: hypothetical protein XP_002342689 [Homo
sapiens]
Length = 204
Score = 201 bits (512), Expect = 7e-52
Identities = 98/101 (97%), Positives = 99/101 (98%)
Query: 1 MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
MD RKVNELRAFVKMCKQDPS+LHTEEM FLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1 MDARKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
Query: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD
Sbjct: 61 DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
>gi|239753617 PREDICTED: similar to heat shock 70kD protein binding
protein [Homo sapiens]
Length = 183
Score = 108 bits (269), Expect = 1e-23
Identities = 55/66 (83%), Positives = 58/66 (87%)
Query: 304 MPGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISKLSA 363
+P + L EILSDPEVLAAMQDPEVMVAFQDV QNPANMSKYQSNPKVMNL+SKLSA
Sbjct: 118 IPSPGKLYPLYEILSDPEVLAAMQDPEVMVAFQDVPQNPANMSKYQSNPKVMNLLSKLSA 177
Query: 364 KFGGQA 369
KFGGQA
Sbjct: 178 KFGGQA 183
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 75.1 bits (183), Expect = 9e-14
Identities = 79/325 (24%), Positives = 142/325 (43%), Gaps = 23/325 (7%)
Query: 8 ELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEE---KPDSKK 64
+++++V K++ +H E E +M +PP KE+ +P KK
Sbjct: 98 DIKSWVSEIKKEEDKMHFHET----ETFPAMKDNLPPVRGSNSCLHVGKEKYSKRPTKKK 153
Query: 65 VEEDLKA-DEPSSEESDLEIDKE----GVIEPDTDAPQEMGDENAEITEEMMD-QANDKK 118
D D+ E+ L+ID++ VI+ + E + A +TE+ D A +K
Sbjct: 154 TPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREK 213
Query: 119 VAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEIN 178
EA N G+ ++A+ +T +I P + + Y RA +KLQ N+A +DC++ +E+
Sbjct: 214 EKGNEAFNSGDYEEAVMYYTRSISALPTV-VAYNNRAQAEIKLQNWNSAFQDCEKVLELE 272
Query: 179 PDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDED-ASAMLKEVQPRAQKIAEHRRK 237
P + + R ++ EA DL+ ++ D D A L EV+ R K +E +
Sbjct: 273 PGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVE-RDLKNSEAASE 331
Query: 238 YERKREE---REIKERIERVKKAREEHERAQREEEARRQSGAQYGSFP---GGFPGGMPG 291
+ K + +EI+ + K+ +HE +++ +GA + P G + G
Sbjct: 332 TQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTG 391
Query: 292 NFPGG-MPGMGGGMPGMAGMPGLNE 315
GG P G G G ++
Sbjct: 392 KAEGGKRPARGAPQRGQTPEAGADK 416
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/173 (23%), Positives = 87/173 (50%), Gaps = 4/173 (2%)
Query: 97 QEMGDENAEITEEMMDQANDK--KVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKR 154
++ GD ++ + + D+ K K + +ND + A+ +++ +K+N + +Y R
Sbjct: 604 KQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNR 663
Query: 155 ASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYD 214
A ++KL + A +DCD+A+++ + + + R AH+ L +++++ DL LD
Sbjct: 664 ALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPS 723
Query: 215 EDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQRE 267
+ M E R + + + +++E R+I+ I+ V + +EE R E
Sbjct: 724 IIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIE--IQEVNEGKEEPGRPAGE 774
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 100 GDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDA-IKLNPRLAILYAKRASVF 158
G + AE + Q N+ + A G+ AI L A ++ L+ILY+ RA+ +
Sbjct: 438 GGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACY 497
Query: 159 VKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLD 212
+K + I+DC+RA+E++P S +P R A+ L + +A D ++D
Sbjct: 498 LKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQID 551
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 75.1 bits (183), Expect = 9e-14
Identities = 79/325 (24%), Positives = 142/325 (43%), Gaps = 23/325 (7%)
Query: 8 ELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEE---KPDSKK 64
+++++V K++ +H E E +M +PP KE+ +P KK
Sbjct: 98 DIKSWVSEIKKEEDKMHFHET----ETFPAMKDNLPPVRGSNSCLHVGKEKYSKRPTKKK 153
Query: 65 VEEDLKA-DEPSSEESDLEIDKE----GVIEPDTDAPQEMGDENAEITEEMMD-QANDKK 118
D D+ E+ L+ID++ VI+ + E + A +TE+ D A +K
Sbjct: 154 TPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREK 213
Query: 119 VAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEIN 178
EA N G+ ++A+ +T +I P + + Y RA +KLQ N+A +DC++ +E+
Sbjct: 214 EKGNEAFNSGDYEEAVMYYTRSISALPTV-VAYNNRAQAEIKLQNWNSAFQDCEKVLELE 272
Query: 179 PDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDED-ASAMLKEVQPRAQKIAEHRRK 237
P + + R ++ EA DL+ ++ D D A L EV+ R K +E +
Sbjct: 273 PGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVE-RDLKNSEAASE 331
Query: 238 YERKREE---REIKERIERVKKAREEHERAQREEEARRQSGAQYGSFP---GGFPGGMPG 291
+ K + +EI+ + K+ +HE +++ +GA + P G + G
Sbjct: 332 TQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTG 391
Query: 292 NFPGG-MPGMGGGMPGMAGMPGLNE 315
GG P G G G ++
Sbjct: 392 KAEGGKRPARGAPQRGQTPEAGADK 416
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/173 (23%), Positives = 87/173 (50%), Gaps = 4/173 (2%)
Query: 97 QEMGDENAEITEEMMDQANDK--KVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKR 154
++ GD ++ + + D+ K K + +ND + A+ +++ +K+N + +Y R
Sbjct: 604 KQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNR 663
Query: 155 ASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYD 214
A ++KL + A +DCD+A+++ + + + R AH+ L +++++ DL LD
Sbjct: 664 ALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPS 723
Query: 215 EDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQRE 267
+ M E R + + + +++E R+I+ I+ V + +EE R E
Sbjct: 724 IIEAKMELEEVTRLLNLKDKTAPFNKEKERRKIE--IQEVNEGKEEPGRPAGE 774
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 100 GDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDA-IKLNPRLAILYAKRASVF 158
G + AE + Q N+ + A G+ AI L A ++ L+ILY+ RA+ +
Sbjct: 438 GGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACY 497
Query: 159 VKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLD 212
+K + I+DC+RA+E++P S +P R A+ L + +A D ++D
Sbjct: 498 LKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQID 551
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 62.4 bits (150), Expect = 6e-10
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 8/136 (5%)
Query: 91 PDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPR---- 146
P + P+ G A + +D+A K + G+ ++AI +T+AI L P
Sbjct: 94 PGSGHPEGPG---AHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNV 150
Query: 147 -LAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDL 205
L+ Y RA+ F +LQK +DC +A+E+NP + R KAH L + +E D+
Sbjct: 151 DLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDV 210
Query: 206 ALACKLDYDEDASAML 221
C L+ ++ +ML
Sbjct: 211 TAVCILEGFQNQQSML 226
Score = 47.0 bits (110), Expect = 3e-05
Identities = 54/216 (25%), Positives = 99/216 (45%), Gaps = 26/216 (12%)
Query: 29 RFLREWVESMGGKV--PPATQKAKSEENTKEEKPDSKKVEED---LKADEPSSEESDLEI 83
+F++ + S + P + KS+E+ K+++ ++ +V+E+ LKA + EE+ +I
Sbjct: 255 QFIKSYFSSFTDDIISQPMLKGEKSDED-KDKEGEALEVKENSGYLKAKQYMEEENYDKI 313
Query: 84 DKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKL 143
E +E+ E + E ++ +A + +L K I L +KL
Sbjct: 314 ISE--------CSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKL 365
Query: 144 NPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAH 203
I KR S++++ Q+P + +D + A +I+P +A Y RG+ LL EEA
Sbjct: 366 RANALI---KRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAV- 421
Query: 204 DLALACKLDYDEDASAMLKEVQPRAQK-IAEHRRKY 238
D+DE + +AQK A +R+ Y
Sbjct: 422 -------ADFDECIRLRPESALAQAQKCFALYRQAY 450
Score = 35.8 bits (81), Expect = 0.063
Identities = 21/64 (32%), Positives = 31/64 (48%)
Query: 126 NDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPY 185
N ++Q A+ F + IK PR A YA A Q+ A D+ I++ PD+A Y
Sbjct: 454 NSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTY 513
Query: 186 KWRG 189
+G
Sbjct: 514 VHKG 517
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 59.7 bits (143), Expect = 4e-09
Identities = 42/165 (25%), Positives = 77/165 (46%), Gaps = 13/165 (7%)
Query: 69 LKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDG 128
L +P +E K V+ P+++G +++ D+ N+ + +
Sbjct: 52 LAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGK-----ADQLKDEGNNH-------MKEE 99
Query: 129 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWR 188
A+D +T AI+L+P A+ Y RA+ KL AI+DC++AI I+ ++ Y
Sbjct: 100 NYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRM 159
Query: 189 GKAHRLLGHWEEAAHDLALACKLDYDEDA-SAMLKEVQPRAQKIA 232
G A L +EEA A LD + D+ + LK + + ++++
Sbjct: 160 GLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVS 204
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 57.4 bits (137), Expect = 2e-08
Identities = 60/243 (24%), Positives = 105/243 (43%), Gaps = 20/243 (8%)
Query: 48 KAK-SEENTKEEKPDSKKVEEDLKADEPSSEESDL-EIDKEGVIEPDTDAPQEMGDENAE 105
KAK S + T+EE ++ D +A + L E+DK+ D+ E + +E
Sbjct: 68 KAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKD-------DSTHESLSQESE 120
Query: 106 ITEEMMDQANDKKVAAIEALN----DGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKL 161
E+ + + K + E N G+ +AID +T + +P +L RAS + +L
Sbjct: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180
Query: 162 QKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAML 221
+K A DC+ A+ +N + Y RG A L EEA D +L+ + +
Sbjct: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEAT-- 238
Query: 222 KEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSF 281
E++ +Q +A Y +E I+ + R++ E Q +++A + G F
Sbjct: 239 NELRKISQALASKENSY-----PKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293
Query: 282 PGG 284
G
Sbjct: 294 KEG 296
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/162 (25%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 61 DSKKVEEDLKADEPSSEESDLEIDK--EGVIEPDTDAPQEM--------GDENAEITEEM 110
++KK E + EP++ E+ E+ K + + + P+E G+ ++
Sbjct: 219 EAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQN 278
Query: 111 MDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRD 170
QA +K +G+ ++AI+ +T I + A+L A RA ++K+QK A +D
Sbjct: 279 KQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKD 338
Query: 171 CDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLD 212
C +AI ++ ++ + RG A LG EA D L+
Sbjct: 339 CTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 380
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 57.4 bits (137), Expect = 2e-08
Identities = 60/243 (24%), Positives = 105/243 (43%), Gaps = 20/243 (8%)
Query: 48 KAK-SEENTKEEKPDSKKVEEDLKADEPSSEESDL-EIDKEGVIEPDTDAPQEMGDENAE 105
KAK S + T+EE ++ D +A + L E+DK+ D+ E + +E
Sbjct: 68 KAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKD-------DSTHESLSQESE 120
Query: 106 ITEEMMDQANDKKVAAIEALN----DGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKL 161
E+ + + K + E N G+ +AID +T + +P +L RAS + +L
Sbjct: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180
Query: 162 QKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAML 221
+K A DC+ A+ +N + Y RG A L EEA D +L+ + +
Sbjct: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEAT-- 238
Query: 222 KEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSF 281
E++ +Q +A Y +E I+ + R++ E Q +++A + G F
Sbjct: 239 NELRKISQALASKENSY-----PKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293
Query: 282 PGG 284
G
Sbjct: 294 KEG 296
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/162 (25%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 61 DSKKVEEDLKADEPSSEESDLEIDK--EGVIEPDTDAPQEM--------GDENAEITEEM 110
++KK E + EP++ E+ E+ K + + + P+E G+ ++
Sbjct: 219 EAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQN 278
Query: 111 MDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRD 170
QA +K +G+ ++AI+ +T I + A+L A RA ++K+QK A +D
Sbjct: 279 KQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKD 338
Query: 171 CDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLD 212
C +AI ++ ++ + RG A LG EA D L+
Sbjct: 339 CTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 380
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 57.0 bits (136), Expect = 3e-08
Identities = 44/176 (25%), Positives = 82/176 (46%), Gaps = 19/176 (10%)
Query: 102 ENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKL 161
E + +E+ +Q N V + +A + AI NP +A+ Y RA ++K+
Sbjct: 21 EKSPSAQELKEQGNRLFVGR-------KYPEAAACYGRAITRNPLVAVYYTNRALCYLKM 73
Query: 162 QKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEA------AHDLALACKLDYDE 215
Q+ A+ DC RA+E++ S + + + G+ + ++EA A+ LA +L++ +
Sbjct: 74 QQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGD 133
Query: 216 DASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEH--ERAQREEE 269
D + L+ + + E RR + +E E+ + R+ A E E QR E
Sbjct: 134 DIPSALRIAKKKRWNSIEERRIH----QESELHSYLSRLIAAERERELEECQRNHE 185
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 56.6 bits (135), Expect = 3e-08
Identities = 52/202 (25%), Positives = 92/202 (45%), Gaps = 29/202 (14%)
Query: 57 EEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQAND 116
EE+P + KVE D SSE +D+E +IE + + E + E + + ++ N+
Sbjct: 71 EEEPGADKVENKSNEDVNSSE-----LDEEYLIELEKNMSDEEKQKRREESTRLKEEGNE 125
Query: 117 --KKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRA 174
KK IEA + +A+++ + +IL++ RA+ +K K AI DC +A
Sbjct: 126 QFKKGDYIEA--ESSYSRALEMCPSCFQ--KERSILFSNRAAARMKQDKKEMAINDCSKA 181
Query: 175 IEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEH 234
I++NP + R + + +EA D K ++D S H
Sbjct: 182 IQLNPSYIRAILRRAELYEKTDKLDEALEDY----KSILEKDPSI--------------H 223
Query: 235 RRKYERKREEREIKERIERVKK 256
+ + R ++I+ER ER+K+
Sbjct: 224 QAREACMRLPKQIEERNERLKE 245
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 55.1 bits (131), Expect = 1e-07
Identities = 39/149 (26%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
Query: 111 MDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRD 170
M+Q N+ K +AL+ G + A+ +++AIKL+P +LY+ R++ + K A D
Sbjct: 1 MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED 60
Query: 171 CDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKE-VQPRAQ 229
+ +++ PD + Y + A L +EEA K E + LKE +Q
Sbjct: 61 GCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLK---HEANNPQLKEGLQNMEA 117
Query: 230 KIAEHRRKYERKREEREIKERIERVKKAR 258
++AE RK+ + +++E + R
Sbjct: 118 RLAE--RKFMNPFNMPNLYQKLESDPRTR 144
Score = 53.5 bits (127), Expect = 3e-07
Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 6/105 (5%)
Query: 112 DQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDC 171
D A ++K E G+ +A+ +T+AIK NP+ A LY+ RA+ + KL + A++DC
Sbjct: 358 DLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDC 417
Query: 172 DRAIEINPDSAQPYKWRGKAHRLLGHWEEA------AHDLALACK 210
+ I++ P + Y + A + + +A A DL +CK
Sbjct: 418 EECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCK 462
Score = 35.4 bits (80), Expect = 0.082
Identities = 73/375 (19%), Positives = 138/375 (36%), Gaps = 42/375 (11%)
Query: 18 QDPSVLHT------EEMRFLREWVESMGGKVPPATQKAKSEENTKEEKPDSKKV---EED 68
QDP ++ T ++ + E E PP +K E +E+ P++KK E++
Sbjct: 171 QDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKE 230
Query: 69 LKADEPSSEESDLEI---DKEGVIEP--------DTDAPQEMGDENA--EITEEMMD--- 112
L D ++ D + DK ++P E GD N E+ E+ ++
Sbjct: 231 LGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGR 290
Query: 113 -QANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDC 171
D + A G + + DAI + ++ + V K Q+ +++
Sbjct: 291 ENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNK-SLAEHRTPDVLKKCQQAEKILKEQ 349
Query: 172 DRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKI 231
+R INPD A K +G G + +A Y E K+ + + +
Sbjct: 350 ERLAYINPDLALEEKNKGNECFQKGDYPQAMKH--------YTEAIKRNPKDAKLYSNRA 401
Query: 232 AEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPG 291
A + + E + ++ +E I+ + + R EA + + +
Sbjct: 402 ACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALD--LDS 459
Query: 292 NFPGGMPGMGGGMPGMAGMPGLNE-----ILSDPEVLAAMQDPEVMVAFQDVAQNPANMS 346
+ G M E ++DPEV M DP + + + + ++P +S
Sbjct: 460 SCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALS 519
Query: 347 KYQSNPKVMNLISKL 361
++ NP + I KL
Sbjct: 520 EHLKNPVIAQKIQKL 534
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/162 (25%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 61 DSKKVEEDLKADEPSSEESDLEIDK--EGVIEPDTDAPQEM--------GDENAEITEEM 110
++KK E + EP++ E+ E+ K + + + P+E G+ ++
Sbjct: 60 EAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQN 119
Query: 111 MDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRD 170
QA +K +G+ ++AI+ +T I + A+L A RA ++K+QK A +D
Sbjct: 120 KQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKD 179
Query: 171 CDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLD 212
C +AI ++ ++ + RG A LG EA D L+
Sbjct: 180 CTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 221
Score = 42.7 bits (99), Expect = 5e-04
Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 10/146 (6%)
Query: 139 DAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHW 198
DA NP +L RAS + +L+K A DC+ A+ +N + Y RG A L
Sbjct: 2 DADPYNP---VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 58
Query: 199 EEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAR 258
EEA D +L+ + + E++ +Q +A Y +E I+ + R
Sbjct: 59 EEAKKDYERVLELEPNNFEAT--NELRKISQALASKENSY-----PKEADIVIKSTEGER 111
Query: 259 EEHERAQREEEARRQSGAQYGSFPGG 284
++ E Q +++A + G F G
Sbjct: 112 KQIEAQQNKQQAISEKDRGNGFFKEG 137
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 10/135 (7%)
Query: 90 EPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAI 149
EP D P D + EE+ QAND A + + AI ++ AI+LNP AI
Sbjct: 13 EPPRDEPP--ADGALKRAEELKTQANDYFKAK-------DYENAIKFYSQAIELNPSNAI 63
Query: 150 LYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALAC 209
Y R+ +++ + A+ D RAIE++ + Y R ++ LG + A D
Sbjct: 64 YYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVV 123
Query: 210 KL-DYDEDASAMLKE 223
K+ +D+DA +E
Sbjct: 124 KVKPHDKDAKMKYQE 138
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 53.1 bits (126), Expect = 4e-07
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 22/173 (12%)
Query: 117 KKVAAIEALNDGELQKAIDLFTDAIKLNPRL----AILYAKRASVFVKLQKPNAAIRDCD 172
KK +A +G + A +L+T+A+ ++P A LY R +V KL+K + AI DC
Sbjct: 203 KKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 262
Query: 173 RAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIA 232
A++++ + Y R + + +EEA D + + ++ +LK Q +K
Sbjct: 263 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKK-- 320
Query: 233 EHRRKY------ERKREEREIKERIERVKKAREEH--------ERAQREEEAR 271
R+ Y ++ E EIK+ K+A H Q+EEE +
Sbjct: 321 SKRKDYYKILGVDKNASEDEIKKAYR--KRALMHHPDRHSGASAEVQKEEEKK 371
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/138 (21%), Positives = 61/138 (44%), Gaps = 3/138 (2%)
Query: 145 PRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHD 204
P+ A Y RA+ + L + A+ D +++ ++ + + GK H LG+ A
Sbjct: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
Query: 205 LALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERA 264
A +LD+ +A ++ A + E+ + E E+R+ ++ + + +A E
Sbjct: 63 FQRALELDH---KNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPAC 119
Query: 265 QREEEARRQSGAQYGSFP 282
R + + + A G +P
Sbjct: 120 HRFKILKAECLAMLGRYP 137
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 53.1 bits (126), Expect = 4e-07
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 22/173 (12%)
Query: 117 KKVAAIEALNDGELQKAIDLFTDAIKLNPRL----AILYAKRASVFVKLQKPNAAIRDCD 172
KK +A +G + A +L+T+A+ ++P A LY R +V KL+K + AI DC
Sbjct: 259 KKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 318
Query: 173 RAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIA 232
A++++ + Y R + + +EEA D + + ++ +LK Q +K
Sbjct: 319 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRK-- 376
Query: 233 EHRRKY------ERKREEREIKERIERVKKAREEH--------ERAQREEEAR 271
R+ Y ++ E EIK+ K+A H Q+EEE +
Sbjct: 377 SKRKDYYKILGVDKNASEDEIKKAYR--KRALMHHPDRHSGASAEVQKEEEKK 427
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/154 (21%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
Query: 129 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWR 188
+ +A + +T AI + P+ A Y RA+ + L + A+ D +++ ++ + +
Sbjct: 43 DYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLRE 102
Query: 189 GKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEREIK 248
GK H LG+ A A +LD+ +A ++ A + E+ + E E+R+ +
Sbjct: 103 GKCHLSLGNAMAACRSFQRALELDH---KNAQAQQEFKNANAVMEYEKIAETDFEKRDFR 159
Query: 249 ERIERVKKAREEHERAQREEEARRQSGAQYGSFP 282
+ + + +A E R + + + A G +P
Sbjct: 160 KVVFCMDRALEFAPACHRFKILKAECLAMLGRYP 193
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 52.4 bits (124), Expect = 7e-07
Identities = 34/110 (30%), Positives = 53/110 (48%)
Query: 107 TEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNA 166
+EE +A K E + + A+ + AI+LNP A+ + RA+ + KL
Sbjct: 84 SEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAG 143
Query: 167 AIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDED 216
A++DC+RAI I+P ++ Y G A L EA A +LD D +
Sbjct: 144 AVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNE 193
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 50.8 bits (120), Expect = 2e-06
Identities = 32/108 (29%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 123 EALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSA 182
+A +DG+ AI L+ +A+ ++P+ ILY+ R++ ++K+Q+ + A+ D +A +NP
Sbjct: 67 QACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWP 126
Query: 183 QPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQK 230
+ Y +G A + LG +A A A L D + +L + A K
Sbjct: 127 KAYFRQGVALQYLGRHADAL--AAFASGLAQDPKSLQLLVGMVEAAMK 172
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 49.3 bits (116), Expect = 6e-06
Identities = 68/277 (24%), Positives = 118/277 (42%), Gaps = 42/277 (15%)
Query: 13 VKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKAD 72
+ + K+D L +E R + S+ GK +++ KEEK S++ +L+ +
Sbjct: 538 IDLAKKDLEKLKRKEKRKKK----SVAGK----EDNTDTDQEKKEEKGVSERENNELEVE 589
Query: 73 EPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDGELQK 132
E S E SD E ++E E + D + G+ + E E ++AN + A QK
Sbjct: 590 E-SQEVSDHEDEEEEEEEEEDDI--DGGESSDESDSESDEKANYQADLANITCEIAIKQK 646
Query: 133 AIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAH 192
ID ++ K L Y + KL IRD R +
Sbjct: 647 LIDELENSQKRLQTLKKQYEE------KLMMLQHKIRDTQLE-------------RDQVL 687
Query: 193 RLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRR------KYER--KREE 244
+ LG E + + A + +Y++ AM KE+Q EH R +YE+ K+ +
Sbjct: 688 QNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQ 747
Query: 245 REI----KERIERVKKAREEHERAQREEEARRQSGAQ 277
+++ K ++ +K+ +EE E+A+ E R + AQ
Sbjct: 748 QDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQ 784
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 48.5 bits (114), Expect = 9e-06
Identities = 46/209 (22%), Positives = 91/209 (43%), Gaps = 30/209 (14%)
Query: 1 MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSE-------- 52
MD K +L+ F+K + +E+ L ++ M P QKA E
Sbjct: 1 MDADKEKDLQKFLK---------NVDEISNL---IQEMNSDDPVVQQKAVLETEKRLLLM 48
Query: 53 ENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGV---IEPDTDAPQEMGDENAEITEE 109
E +EE + + + + ++ +S EI+ E +E D + EN + +
Sbjct: 49 EEDQEEDECRTTLNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADA 108
Query: 110 MMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIR 169
+ ++ N EA +G + AI +++ ++ + +LY RA ++KL+ A+
Sbjct: 109 LKEKGN-------EAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALV 161
Query: 170 DCDRAIEINPDSAQPYKWRGKAHRLLGHW 198
DC+ A++ + + Y GKA+ L ++
Sbjct: 162 DCEWALKCDEKCTKAYFHMGKANLALKNY 190
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 47.0 bits (110), Expect = 3e-05
Identities = 65/268 (24%), Positives = 113/268 (42%), Gaps = 17/268 (6%)
Query: 8 ELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP-DSKKVE 66
EL +K K++ + EE E V + V + K EE KEE+ ++ E
Sbjct: 479 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE 538
Query: 67 EDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALN 126
ED A +EE E KEG E + + QE G+ AE E + +KKV
Sbjct: 539 EDEGAKSDQAEEGGSE--KEGSSEKE-EGEQEEGETEAEAEGEEAEAKEEKKVEE----K 591
Query: 127 DGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKP--NAAIRDCDRAIEINPDSAQP 184
E+ +L DA P A ++ V K + P + + + ++ P P
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS----PVPKSP 647
Query: 185 YKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREE 244
+ +GK+ EE ++ ++ S + K A+ AE + +++ EE
Sbjct: 648 VEEKGKSPVPKSPVEEKGKSPVSKSPVE-EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE 706
Query: 245 REIKE--RIERVKKAREEHERAQREEEA 270
+E+KE + E+V+K E+ + +++A
Sbjct: 707 KEVKEAPKEEKVEKKEEKPKDVPEKKKA 734
Score = 35.4 bits (80), Expect = 0.082
Identities = 62/278 (22%), Positives = 106/278 (38%), Gaps = 33/278 (11%)
Query: 26 EEMRFLREWVESMGGKVPPATQKAKSE-ENTKEEKPD------SKKVE-EDLKADEPSSE 77
+ M EW + K+ A ++ K + KEE + SK +E E ++ + S E
Sbjct: 283 QNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLE 342
Query: 78 E--SDLEIDKEGVIEPDTDAPQEMGDENAEITEEM------------MDQANDKKVAAIE 123
SD+E + D Q++ +E EM + A D ++AA
Sbjct: 343 RQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYR 402
Query: 124 ALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFV--KLQKPNAAIRDCDRAIEINPDS 181
L +GE + F +I LY R + + K+QKP + +
Sbjct: 403 KLLEGE-ETRFSTFAGSIT-----GPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEI 456
Query: 182 AQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERK 241
+ K + + +LA++ K + E A KE +P A++ +K K
Sbjct: 457 IEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEE--KEEEPEAEEEEVAAKKSPVK 514
Query: 242 REEREIKERIERVKKAREEHERAQREEEARRQSGAQYG 279
E+KE E K+ E E + E+E + A+ G
Sbjct: 515 ATAPEVKEE-EGEKEEEEGQEEEEEEDEGAKSDQAEEG 551
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 47.0 bits (110), Expect = 3e-05
Identities = 65/268 (24%), Positives = 113/268 (42%), Gaps = 17/268 (6%)
Query: 8 ELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP-DSKKVE 66
EL +K K++ + EE E V + V + K EE KEE+ ++ E
Sbjct: 103 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE 162
Query: 67 EDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALN 126
ED A +EE E KEG E + + QE G+ AE E + +KKV
Sbjct: 163 EDEGAKSDQAEEGGSE--KEGSSEKE-EGEQEEGETEAEAEGEEAEAKEEKKVEE----K 215
Query: 127 DGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKP--NAAIRDCDRAIEINPDSAQP 184
E+ +L DA P A ++ V K + P + + + ++ P P
Sbjct: 216 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS----PVPKSP 271
Query: 185 YKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREE 244
+ +GK+ EE ++ ++ S + K A+ AE + +++ EE
Sbjct: 272 VEEKGKSPVPKSPVEEKGKSPVSKSPVE-EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE 330
Query: 245 REIKE--RIERVKKAREEHERAQREEEA 270
+E+KE + E+V+K E+ + +++A
Sbjct: 331 KEVKEAPKEEKVEKKEEKPKDVPEKKKA 358
Score = 30.4 bits (67), Expect = 2.6
Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 11/168 (6%)
Query: 114 ANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFV--KLQKPNAAIRDC 171
A D ++AA L +GE + F +I LY R + + K+QKP
Sbjct: 17 ALDIEIAAYRKLLEGE-ETRFSTFAGSIT-----GPLYTHRPPITISSKIQKPKVEAPKL 70
Query: 172 DRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKI 231
+ + + K + + +LA++ K + E A KE +P A++
Sbjct: 71 KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEE--KEEEPEAEEE 128
Query: 232 AEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYG 279
+K K E+KE E K+ E E + E+E + A+ G
Sbjct: 129 EVAAKKSPVKATAPEVKEE-EGEKEEEEGQEEEEEEDEGAKSDQAEEG 175
>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
Length = 1060
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/292 (22%), Positives = 120/292 (41%), Gaps = 42/292 (14%)
Query: 24 HTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEI 83
HT E++ +R VE+ K+ + A+ EE K+ + + K++EE+ A + S LE+
Sbjct: 439 HTVEIKSVRSSVEAERKKLQREVE-AQLEEVRKKSEKEIKQLEEEKAALNVKLQNSLLEV 497
Query: 84 DK-EGVIEPD-------TDAPQEMGDENAEITEEM-----MDQANDK------KVAAIEA 124
+ E I+ + ++PQE+G ++ I E +D+ + + K+AA E
Sbjct: 498 LRLEEFIQQNKTRPTGAEESPQELGRQHCSILETQDPCLKLDETSPRGEEYQDKLAAEEG 557
Query: 125 LNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQ--------KPNAAIRDCDRAIE 176
+ E ++ L + P L L ++ S +L+ K A + +A+E
Sbjct: 558 TSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALE 617
Query: 177 INPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRR 236
Y+ +A + L E L + A L+ RA ++ E R
Sbjct: 618 ---QCTSNYREDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKAR 674
Query: 237 KYERKREEREIKE----------RIERVK-KAREEHERAQREEEARRQSGAQ 277
E K E +K+ + R++ +A EE R + +EE R Q
Sbjct: 675 HQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQELQEERERMQAQQ 726
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/232 (22%), Positives = 89/232 (38%), Gaps = 38/232 (16%)
Query: 54 NTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQ 113
+ ++ K D K E + DE SS S + T A + ++ + E +
Sbjct: 438 SVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKES 497
Query: 114 ANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDR 173
+ KK+ + ND A +++IK + + +K V L +
Sbjct: 498 KDTKKIEGKDEKNDNG---ASGQTSESIKKSEEKKRISSKSPGHMVILDQTKG------- 547
Query: 174 AIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQP----RAQ 229
D +P + RG+ ++ G +E LD D KE+ P + Q
Sbjct: 548 ------DHCRPSR-RGRYEKIHGRSKEKER-----ASLDKKRDKDYRRKEILPFEKMKEQ 595
Query: 230 KIAEHRRKYERKREEREIKERIE------------RVKKAREEHERAQREEE 269
++ EH ++ER R E++ R E R+ + REE ER QRE E
Sbjct: 596 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERE 647
Score = 35.4 bits (80), Expect = 0.082
Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 3/55 (5%)
Query: 222 KEVQPRAQKIAEHRRKYERKREEREI--KERIERVKKAREEHERAQRE-EEARRQ 273
+ +Q +++ R+K ER+R ERE +ERI ++ R+E ER RE EE RRQ
Sbjct: 640 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQ 694
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/232 (22%), Positives = 89/232 (38%), Gaps = 38/232 (16%)
Query: 54 NTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQ 113
+ ++ K D K E + DE SS S + T A + ++ + E +
Sbjct: 456 SVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKES 515
Query: 114 ANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDR 173
+ KK+ + ND A +++IK + + +K V L +
Sbjct: 516 KDTKKIEGKDEKNDNG---ASGQTSESIKKSEEKKRISSKSPGHMVILDQTKG------- 565
Query: 174 AIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQP----RAQ 229
D +P + RG+ ++ G +E LD D KE+ P + Q
Sbjct: 566 ------DHCRPSR-RGRYEKIHGRSKEKER-----ASLDKKRDKDYRRKEILPFEKMKEQ 613
Query: 230 KIAEHRRKYERKREEREIKERIE------------RVKKAREEHERAQREEE 269
++ EH ++ER R E++ R E R+ + REE ER QRE E
Sbjct: 614 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERE 665
Score = 35.4 bits (80), Expect = 0.082
Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 3/55 (5%)
Query: 222 KEVQPRAQKIAEHRRKYERKREEREI--KERIERVKKAREEHERAQRE-EEARRQ 273
+ +Q +++ R+K ER+R ERE +ERI ++ R+E ER RE EE RRQ
Sbjct: 658 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQ 712
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 120 AAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRAS-----VFVKLQKPNAAIRDCDRA 174
+A E + DG A + +K P +A Y R+ F K +KP AIR C
Sbjct: 274 SAEELIRDGRYTDATSKYESVMKTEPSIAE-YTVRSKERICHCFSKDEKPVEAIRVCSEV 332
Query: 175 IEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEH 234
+++ PD+ K R +A+ + ++EA D A + + ++ E R K ++
Sbjct: 333 LQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQK 392
Query: 235 RRKYERKREEREIKERIERVKKARE-----EHERAQREEEARR 272
R Y+ +R K++ E +K R+ + Q EEE ++
Sbjct: 393 RDYYKILGVKRNAKKQ-EIIKAYRKLALQWHPDNFQNEEEKKK 434
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 3/109 (2%)
Query: 128 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKW 187
G+L A+ F A+ +P I Y +RA+VF+ + K AA+ D + I++ D
Sbjct: 51 GQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQ 110
Query: 188 RGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRR 236
RG G +EA D K + E+ KE Q + K E +R
Sbjct: 111 RGHLLLKQGKLDEAEDDFKKVLKSNPSENEE---KEAQSQLIKSDEMQR 156
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/87 (29%), Positives = 44/87 (50%)
Query: 128 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKW 187
G+LQ+A+ + +AI+++P A Y+ + ++Q A++ RAI+INP A +
Sbjct: 365 GKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSN 424
Query: 188 RGKAHRLLGHWEEAAHDLALACKLDYD 214
H+ G+ EA A KL D
Sbjct: 425 LASIHKDSGNIPEAIASYRTALKLKPD 451
Score = 33.9 bits (76), Expect = 0.24
Identities = 32/160 (20%), Positives = 64/160 (40%), Gaps = 6/160 (3%)
Query: 129 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWR 188
++Q A+ +T AI++NP A ++ AS+ AI A+++ PD Y
Sbjct: 400 DVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNL 459
Query: 189 GKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPR---AQKIAEHRRKYERKREER 245
+++ W + + + D+ L V P ++ RK +R
Sbjct: 460 AHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGN 519
Query: 246 EIKERIERVKKAREEHERAQREEEARRQSG---AQYGSFP 282
++I + K EH + + + R + G + +G+ P
Sbjct: 520 LCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHP 559
Score = 33.5 bits (75), Expect = 0.31
Identities = 22/74 (29%), Positives = 34/74 (45%)
Query: 128 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKW 187
G+LQ+AI+ + A++L P Y A+ V A++ A++ NPD
Sbjct: 93 GQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSD 152
Query: 188 RGKAHRLLGHWEEA 201
G + LG EEA
Sbjct: 153 LGNLLKALGRLEEA 166
Score = 32.7 bits (73), Expect = 0.53
Identities = 18/62 (29%), Positives = 31/62 (50%)
Query: 128 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKW 187
G +++A+ L+ A+++ P A ++ ASV + K A+ AI I+P A Y
Sbjct: 331 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN 390
Query: 188 RG 189
G
Sbjct: 391 MG 392
Score = 29.3 bits (64), Expect = 5.9
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 2/87 (2%)
Query: 130 LQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRG 189
L ++ T AIK NP LA Y+ +V+ + + AI A+ + PD Y
Sbjct: 61 LDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLA 120
Query: 190 KAHRLLGHWEEAAHDLALACKLDYDED 216
A G E A A L Y+ D
Sbjct: 121 AALVAAGDMEGAVQ--AYVSALQYNPD 145
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/87 (29%), Positives = 44/87 (50%)
Query: 128 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKW 187
G+LQ+A+ + +AI+++P A Y+ + ++Q A++ RAI+INP A +
Sbjct: 375 GKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSN 434
Query: 188 RGKAHRLLGHWEEAAHDLALACKLDYD 214
H+ G+ EA A KL D
Sbjct: 435 LASIHKDSGNIPEAIASYRTALKLKPD 461
Score = 33.9 bits (76), Expect = 0.24
Identities = 32/160 (20%), Positives = 64/160 (40%), Gaps = 6/160 (3%)
Query: 129 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWR 188
++Q A+ +T AI++NP A ++ AS+ AI A+++ PD Y
Sbjct: 410 DVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNL 469
Query: 189 GKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPR---AQKIAEHRRKYERKREER 245
+++ W + + + D+ L V P ++ RK +R
Sbjct: 470 AHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGN 529
Query: 246 EIKERIERVKKAREEHERAQREEEARRQSG---AQYGSFP 282
++I + K EH + + + R + G + +G+ P
Sbjct: 530 LCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHP 569
Score = 33.5 bits (75), Expect = 0.31
Identities = 22/74 (29%), Positives = 34/74 (45%)
Query: 128 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKW 187
G+LQ+AI+ + A++L P Y A+ V A++ A++ NPD
Sbjct: 103 GQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSD 162
Query: 188 RGKAHRLLGHWEEA 201
G + LG EEA
Sbjct: 163 LGNLLKALGRLEEA 176
Score = 32.7 bits (73), Expect = 0.53
Identities = 18/62 (29%), Positives = 31/62 (50%)
Query: 128 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKW 187
G +++A+ L+ A+++ P A ++ ASV + K A+ AI I+P A Y
Sbjct: 341 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN 400
Query: 188 RG 189
G
Sbjct: 401 MG 402
Score = 29.3 bits (64), Expect = 5.9
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 2/87 (2%)
Query: 130 LQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRG 189
L ++ T AIK NP LA Y+ +V+ + + AI A+ + PD Y
Sbjct: 71 LDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLA 130
Query: 190 KAHRLLGHWEEAAHDLALACKLDYDED 216
A G E A A L Y+ D
Sbjct: 131 AALVAAGDMEGAVQ--AYVSALQYNPD 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,506,605
Number of Sequences: 37866
Number of extensions: 818773
Number of successful extensions: 13386
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 426
Number of HSP's successfully gapped in prelim test: 563
Number of HSP's that attempted gapping in prelim test: 6844
Number of HSP's gapped (non-prelim): 5234
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.