Search of human proteins with 197383100

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
         (487 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]           1013   0.0  
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]            822   0.0  
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]             426   e-119
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            417   e-116
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]             413   e-115
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]             392   e-109
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]             327   2e-89
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             320   1e-87
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]             174   2e-43
gi|109638745 transforming growth factor beta 1 induced transcrip...   169   4e-42
gi|21361591 transforming growth factor beta 1 induced transcript...   169   4e-42
gi|221316659 leupaxin isoform 1 [Homo sapiens]                        155   8e-38
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          155   8e-38
gi|170932518 paxillin isoform 3 [Homo sapiens]                        147   2e-35
gi|170932516 paxillin isoform 2 [Homo sapiens]                        147   2e-35
gi|170932514 paxillin isoform 1 [Homo sapiens]                        147   2e-35
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]            131   1e-30
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   131   2e-30
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   131   2e-30
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   131   2e-30
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   131   2e-30
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   127   2e-29
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              119   5e-27
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]            117   2e-26
gi|13994151 PDZ and LIM domain 1 [Homo sapiens]                       114   3e-25
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]    108   1e-23
gi|87159836 four and a half LIM domains 2 [Homo sapiens]              105   9e-23
gi|87159834 four and a half LIM domains 2 [Homo sapiens]              105   9e-23
gi|42403575 four and a half LIM domains 2 [Homo sapiens]              105   9e-23
gi|87159832 four and a half LIM domains 2 [Homo sapiens]              105   9e-23

>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score = 1013 bits (2620), Expect = 0.0
 Identities = 487/487 (100%), Positives = 487/487 (100%)

Query: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
           MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60

Query: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
           MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ
Sbjct: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120

Query: 121 GDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQI 180
           GDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQI
Sbjct: 121 GDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQI 180

Query: 181 TGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAF 240
           TGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAF
Sbjct: 181 TGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAF 240

Query: 241 KPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAE 300
           KPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAE
Sbjct: 241 KPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAE 300

Query: 301 HIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCEL 360
           HIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCEL
Sbjct: 301 HIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCEL 360

Query: 361 CYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETD 420
           CYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETD
Sbjct: 361 CYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETD 420

Query: 421 YYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKK 480
           YYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKK
Sbjct: 421 YYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKK 480

Query: 481 HAHSVNF 487
           HAHSVNF
Sbjct: 481 HAHSVNF 487


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score =  822 bits (2122), Expect = 0.0
 Identities = 390/392 (99%), Positives = 392/392 (100%)

Query: 96  QKPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRL 155
           ++PTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRL
Sbjct: 205 RQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRL 264

Query: 156 IEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTR 215
           IEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTR
Sbjct: 265 IEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTR 324

Query: 216 SMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSG 275
           SMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSG
Sbjct: 325 SMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSG 384

Query: 276 SVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEF 335
           SVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEF
Sbjct: 385 SVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEF 444

Query: 336 NCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFV 395
           NCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFV
Sbjct: 445 NCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFV 504

Query: 396 CVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCF 455
           CVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCF
Sbjct: 505 CVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCF 564

Query: 456 VCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF 487
           VCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF
Sbjct: 565 VCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF 596



 Score =  197 bits (500), Expect = 2e-50
 Identities = 97/97 (100%), Positives = 97/97 (100%)

Query: 1  MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
          MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1  MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60

Query: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK 97
          MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK 97


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score =  426 bits (1095), Expect = e-119
 Identities = 229/492 (46%), Positives = 298/492 (60%), Gaps = 45/492 (9%)

Query: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
           M ++ V L GPAPWGFRLQGGKDFN+PL+IS L  GGKAAQA V +GD VLSIDG NA  
Sbjct: 1   MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60

Query: 61  MTHLEAQNKIKGCTGSLNMTLQRAS---AAPKPEPVPV-QKPTVTSVCSETSQELAEGQR 116
           +TH+EAQNKI+ C   L++ L RA    + P+    P    P  T   S +  + A    
Sbjct: 61  LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120

Query: 117 RGSQGDSK-QQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFR 175
                DS  QQNG P + +V             DASK+RL+E+TEDWRPR GT QSRSFR
Sbjct: 121 APPPADSAPQQNGQPLRPLVP------------DASKQRLMENTEDWRPRPGTGQSRSFR 168

Query: 176 ILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMP---ESLDSPTSGRPGVT 232
           ILA +TGTE +++ + ++ KK+  SQ P  +  +  +ST   P    +  SPTS  P   
Sbjct: 169 ILAHLTGTEFMQDPDEEHLKKS--SQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAV 226

Query: 233 SLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQ 292
               A  + P  ++ V+   S  +P    P   R S     +G V    S  G       
Sbjct: 227 DPAFAERYAPDKTSTVLTRHS--QPATPTPLQSRTSIVQAAAGGVPGGGSNNG------- 277

Query: 293 DTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEE 352
                         +TP+C  C++VIRG +LVALG ++HPEEF C+ C   +   GF EE
Sbjct: 278 --------------KTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEE 323

Query: 353 KGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLED 412
           KGA++C  CY+  +AP C +C++KI GE++ ALK TWHV CF C AC  PIRN  F++E+
Sbjct: 324 KGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEE 383

Query: 413 GEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSK 472
           G PYCE DY  +FGT CHGC+F I+AGD FLEALG++WHDTCFVC++C  +LEG+TF+SK
Sbjct: 384 GVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSK 443

Query: 473 KDKPLCKKHAHS 484
           KD+PLCK HA S
Sbjct: 444 KDRPLCKSHAFS 455


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  417 bits (1072), Expect = e-116
 Identities = 249/619 (40%), Positives = 324/619 (52%), Gaps = 139/619 (22%)

Query: 3   NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
           +YSV+L GP PWGFRLQGGKDFNMPLTIS +  G KAAQ+ +  GD+V++IDG+N   MT
Sbjct: 2   SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61

Query: 63  HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKPTVTSVCSETSQ-- 109
           HLEAQNKIK  + +L++TLQ++        +A P   P+PV   QK  V S  +   Q  
Sbjct: 62  HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121

Query: 110 ----------------------------------------------ELAEGQRRGSQGDS 123
                                                         +   GQ + +QG  
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQ-AQGSD 180

Query: 124 KQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGT 183
              + P +   V+  +  Y     S    +   ++ ++W  R+   QSRSFRILAQ+TGT
Sbjct: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMTGT 237

Query: 184 --------EHLKESE----------------ADNTKKANNSQEPSPQ-LASSVASTRS-- 216
                   E L+ S                 A +T  +     P+P+    + AS R   
Sbjct: 238 EFMQDPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSV 297

Query: 217 ---MPESLDSPTSGR---PGVTSLTAAAAFKPVGSTGVIKSP-SWQRPNQG---VPSTGR 266
              +P S  SP+ G    P   + + A A+ P  +     SP     P+      PS   
Sbjct: 298 YQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAP 357

Query: 267 ISN---SATYSGSVA------------------------------------PANSALGQT 287
             N   S  YSG  A                                    PA +  G  
Sbjct: 358 NYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQ 417

Query: 288 QPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYI 347
            P      VQRAE  PA  RTP+C HCN VIRGPFLVA+G+SWHPEEF CA+CK ++A +
Sbjct: 418 VPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADV 477

Query: 348 GFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNV 407
            FVEE+  +YCE CYE+FFAP C +C  KI+GEV+ AL+QTWH +CFVC AC KP  N++
Sbjct: 478 CFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSL 537

Query: 408 FHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQ 467
           FH+EDGEPYCE DY  LF T CHGC+FP+EAGD F+EALG+TWHDTCF+C+VC  +LEGQ
Sbjct: 538 FHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQ 597

Query: 468 TFFSKKDKPLCKKHAHSVN 486
            F+SKKD+PLCKKHAH++N
Sbjct: 598 PFYSKKDRPLCKKHAHTIN 616


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score =  413 bits (1062), Expect = e-115
 Identities = 224/487 (45%), Positives = 289/487 (59%), Gaps = 69/487 (14%)

Query: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
           M ++ V L GPAPWGFRLQGGKDFN+PL+IS L  GGKAAQA V +GD VLSIDG NA  
Sbjct: 1   MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60

Query: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
           +TH+EAQNKI+ C   L++ L RA    + +P  VQ P                      
Sbjct: 61  LTHIEAQNKIRACGERLSLGLSRAQPV-QSKPQKVQTP---------------------- 97

Query: 121 GDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQI 180
              KQ   P R             P   DASK+RL+E+TEDWRPR GT QSRSFRILA +
Sbjct: 98  --DKQ---PLR-------------PLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHL 139

Query: 181 TGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMP---ESLDSPTSGRPGVTSLTAA 237
           TGTE +++ + ++ KK+  SQ P  +  +  +ST   P    +  SPTS  P       A
Sbjct: 140 TGTEFMQDPDEEHLKKS--SQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFA 197

Query: 238 AAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQ 297
             + P  ++ V+   S  +P    P   R S     +G V    S  G            
Sbjct: 198 ERYAPDKTSTVLTRHS--QPATPTPLQSRTSIVQAAAGGVPGGGSNNG------------ 243

Query: 298 RAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALY 357
                    +TP+C  C++VIRG +LVALG ++HPEEF C+ C   +   GF EEKGA++
Sbjct: 244 ---------KTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIF 294

Query: 358 CELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 417
           C  CY+  +AP C +C++KI GE++ ALK TWHV CF C AC  PIRN  F++E+G PYC
Sbjct: 295 CPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYC 354

Query: 418 ETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPL 477
           E DY  +FGT CHGC+F I+AGD FLEALG++WHDTCFVC++C  +LEG+TF+SKKD+PL
Sbjct: 355 ERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPL 414

Query: 478 CKKHAHS 484
           CK HA S
Sbjct: 415 CKSHAFS 421


>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
          Length = 234

 Score =  392 bits (1007), Expect = e-109
 Identities = 197/203 (97%), Positives = 197/203 (97%), Gaps = 6/203 (2%)

Query: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
           MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60

Query: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
           MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ
Sbjct: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120

Query: 121 GDSKQQNG------PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 174
           GDSKQQNG      PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF
Sbjct: 121 GDSKQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSF 180

Query: 175 RILAQITGTEHLKESEADNTKKA 197
           RILAQITGTEHLKESEADNTKKA
Sbjct: 181 RILAQITGTEHLKESEADNTKKA 203


>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
          Length = 214

 Score =  327 bits (837), Expect = 2e-89
 Identities = 170/198 (85%), Positives = 171/198 (86%), Gaps = 16/198 (8%)

Query: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
           MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
Sbjct: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60

Query: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
           MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQK T               Q   + 
Sbjct: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKT---------------QVTNNP 105

Query: 121 GDSK-QQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQ 179
           G  K     PPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQ
Sbjct: 106 GTVKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQ 165

Query: 180 ITGTEHLKESEADNTKKA 197
           ITGTEHLKESEADNTKKA
Sbjct: 166 ITGTEHLKESEADNTKKA 183


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  320 bits (821), Expect = 1e-87
 Identities = 154/287 (53%), Positives = 189/287 (65%), Gaps = 24/287 (8%)

Query: 200 SQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQ 259
           S  P+   A SVA +    E    P S  P VT  + +  F P  ST  I         Q
Sbjct: 464 SPAPNYNPAPSVAYSGGPAE----PASRPPWVTDDSFSQKFAPGKSTTSISK-------Q 512

Query: 260 GVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIR 319
            +P  G             PA +  G   P      VQRAE  PA  RTP+C HCN VIR
Sbjct: 513 TLPRGG-------------PAYTPAGPQVPPLARGTVQRAERFPASSRTPLCGHCNNVIR 559

Query: 320 GPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILG 379
           GPFLVA+G+SWHPEEF CA+CK ++A + FVEE+  +YCE CYE+FFAP C +C  KI+G
Sbjct: 560 GPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG 619

Query: 380 EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAG 439
           EV+ AL+QTWH +CFVC AC KP  N++FH+EDGEPYCE DY  LF T CHGC+FP+EAG
Sbjct: 620 EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAG 679

Query: 440 DMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVN 486
           D F+EALG+TWHDTCF+C+VC  +LEGQ F+SKKD+PLCKKHAH++N
Sbjct: 680 DKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTIN 726



 Score =  117 bits (293), Expect = 2e-26
 Identities = 56/98 (57%), Positives = 73/98 (74%), Gaps = 3/98 (3%)

Query: 3   NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
           +YSV+L GP PWGFRLQGGKDFNMPLTIS +  G KAAQ+ +  GD+V++IDG+N   MT
Sbjct: 2   SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61

Query: 63  HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTV 100
           HLEAQNKIK  + +L++TLQ++    +P P+    P V
Sbjct: 62  HLEAQNKIKSASYNLSLTLQKSK---RPIPISTTAPPV 96



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 40/143 (27%), Positives = 73/143 (51%), Gaps = 10/143 (6%)

Query: 151 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASS 210
           S+ +  ++ ++W  R+   QSRSFRILAQ+TGTE +++ + +  ++++   E +P + +S
Sbjct: 252 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSSTPIEHAP-VCTS 310

Query: 211 VASTRSMPESLDSPTSGRPGVTS--LTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRIS 268
            A+T  +P S   P +  P   S  L  AAA   + S       S        P+     
Sbjct: 311 QATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPAS-------SPADSPRP 363

Query: 269 NSATYSGSVAPANSALGQTQPSD 291
            +++YS +VA +++    T  S+
Sbjct: 364 QASSYSPAVAASSAPATHTSYSE 386


>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
          Length = 222

 Score =  174 bits (440), Expect = 2e-43
 Identities = 100/202 (49%), Positives = 125/202 (61%), Gaps = 17/202 (8%)

Query: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
           M ++ V L GPAPWGFRLQGGKDFN+PL+IS L  GGKAAQA V +GD VLSIDG NA  
Sbjct: 1   MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60

Query: 61  MTHLEAQNKIKGCTGSLNMTLQRA----SAAPKPEPVPVQKPTVTSVCSETSQELAEGQR 116
           +TH+EAQNKI+ C   L++ L RA    S   K        P  T   S +  + A    
Sbjct: 61  LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120

Query: 117 RGSQGDS-KQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFR 175
                DS  QQNG P + +V             DASK+RL+E+TEDWRPR GT QSRSFR
Sbjct: 121 APPPADSAPQQNGQPLRPLV------------PDASKQRLMENTEDWRPRPGTGQSRSFR 168

Query: 176 ILAQITGTEHLKESEADNTKKA 197
           ILA +TGTE +++ + ++ KK+
Sbjct: 169 ILAHLTGTEFMQDPDEEHLKKS 190


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  169 bits (429), Expect = 4e-42
 Identities = 96/298 (32%), Positives = 144/298 (48%), Gaps = 24/298 (8%)

Query: 200 SQEPSPQLASSV-----ASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSW 254
           SQ PS ++AS       +  +  P    SP+ G P  ++ +A      +     + S S 
Sbjct: 113 SQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRL-----MASLSD 167

Query: 255 QRPNQGVPSTGRISN---SATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTP-- 309
            R    +P++G       S+T  GS +P       T     DT++   +   + +  P  
Sbjct: 168 FRVQNHLPASGPTQPPVVSSTNEGSPSPPEP----TGKGSLDTMLGLLQSDLSRRGVPTQ 223

Query: 310 ---MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
              +C  CN+ I G  + ALG++WHPE F C  C   +    F E+ GA +C  CY + F
Sbjct: 224 AKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 283

Query: 367 APECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
           +P CG C + I  ++++AL   WH   F CV+CG+P  +  FH  +G PYC  D+  LF 
Sbjct: 284 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343

Query: 427 TICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHS 484
             C GC+ PI   D ++ AL   WH  CFVC  C     G +FF  + +PLC+ H H+
Sbjct: 344 PRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHA 399



 Score =  134 bits (337), Expect = 2e-31
 Identities = 101/337 (29%), Positives = 145/337 (43%), Gaps = 53/337 (15%)

Query: 187 KESEADNTKKANNSQEPSPQL--ASSVASTRSMPESLDS----------PTSG--RPGVT 232
           KE ++++ K+ +    PSP L  AS+ ++T  +   + S          P SG  +P V 
Sbjct: 126 KEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVV 185

Query: 233 SLTAAAAFKPVGSTG---------VIKSPSWQRPNQGVPSTGRI---SNSATYSGSVAPA 280
           S T   +  P   TG         +++S   +R   GVP+  +    S +   +G V  A
Sbjct: 186 SSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRR---GVPTQAKGLCGSCNKPIAGQVVTA 242

Query: 281 ---------------NSALGQTQPSDQDTLVQRAEHIPA---GKRTPMCAHCNQVIRGPF 322
                          ++ALG +   ++D     A   P     + +P C  CNQ IR   
Sbjct: 243 LGRAWHPEHFVCGGCSTALGGSSFFEKDG----APFCPECYFERFSPRCGFCNQPIRHKM 298

Query: 323 LVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVI 382
           + ALG  WHPE F C  C       GF E +G  YC   + + FAP C  CQ  IL   I
Sbjct: 299 VTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYI 358

Query: 383 SALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMF 442
           SAL   WH  CFVC  C  P     F   +G P CE  ++A  G++C  C  P+      
Sbjct: 359 SALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTG--RC 416

Query: 443 LEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           + ALG  +H   F C+ C   L   +F  +  KP C+
Sbjct: 417 VSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 453



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 36/118 (30%), Positives = 51/118 (43%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C   I   ++ AL   WHP+ F C  C    +   F E +G   CE  +      
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
            C  C   + G  +SAL + +H   F C  C +P+    F    G+PYC+  +  LFG
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 461



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 21/61 (34%), Positives = 31/61 (50%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           +R  +CA C   + G  + ALG+ +HP+ F C  C   +    F E  G  YC+ C+ K 
Sbjct: 400 RRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKL 459

Query: 366 F 366
           F
Sbjct: 460 F 460


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  169 bits (429), Expect = 4e-42
 Identities = 96/298 (32%), Positives = 144/298 (48%), Gaps = 24/298 (8%)

Query: 200 SQEPSPQLASSV-----ASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSW 254
           SQ PS ++AS       +  +  P    SP+ G P  ++ +A      +     + S S 
Sbjct: 96  SQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRL-----MASLSD 150

Query: 255 QRPNQGVPSTGRISN---SATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTP-- 309
            R    +P++G       S+T  GS +P       T     DT++   +   + +  P  
Sbjct: 151 FRVQNHLPASGPTQPPVVSSTNEGSPSPPEP----TGKGSLDTMLGLLQSDLSRRGVPTQ 206

Query: 310 ---MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
              +C  CN+ I G  + ALG++WHPE F C  C   +    F E+ GA +C  CY + F
Sbjct: 207 AKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 266

Query: 367 APECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
           +P CG C + I  ++++AL   WH   F CV+CG+P  +  FH  +G PYC  D+  LF 
Sbjct: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326

Query: 427 TICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHS 484
             C GC+ PI   D ++ AL   WH  CFVC  C     G +FF  + +PLC+ H H+
Sbjct: 327 PRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHA 382



 Score =  134 bits (337), Expect = 2e-31
 Identities = 101/337 (29%), Positives = 145/337 (43%), Gaps = 53/337 (15%)

Query: 187 KESEADNTKKANNSQEPSPQL--ASSVASTRSMPESLDS----------PTSG--RPGVT 232
           KE ++++ K+ +    PSP L  AS+ ++T  +   + S          P SG  +P V 
Sbjct: 109 KEDQSEDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVV 168

Query: 233 SLTAAAAFKPVGSTG---------VIKSPSWQRPNQGVPSTGRI---SNSATYSGSVAPA 280
           S T   +  P   TG         +++S   +R   GVP+  +    S +   +G V  A
Sbjct: 169 SSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRR---GVPTQAKGLCGSCNKPIAGQVVTA 225

Query: 281 ---------------NSALGQTQPSDQDTLVQRAEHIPA---GKRTPMCAHCNQVIRGPF 322
                          ++ALG +   ++D     A   P     + +P C  CNQ IR   
Sbjct: 226 LGRAWHPEHFVCGGCSTALGGSSFFEKDG----APFCPECYFERFSPRCGFCNQPIRHKM 281

Query: 323 LVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVI 382
           + ALG  WHPE F C  C       GF E +G  YC   + + FAP C  CQ  IL   I
Sbjct: 282 VTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYI 341

Query: 383 SALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMF 442
           SAL   WH  CFVC  C  P     F   +G P CE  ++A  G++C  C  P+      
Sbjct: 342 SALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTG--RC 399

Query: 443 LEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           + ALG  +H   F C+ C   L   +F  +  KP C+
Sbjct: 400 VSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 436



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 36/118 (30%), Positives = 51/118 (43%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C   I   ++ AL   WHP+ F C  C    +   F E +G   CE  +      
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
            C  C   + G  +SAL + +H   F C  C +P+    F    G+PYC+  +  LFG
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 21/61 (34%), Positives = 31/61 (50%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           +R  +CA C   + G  + ALG+ +HP+ F C  C   +    F E  G  YC+ C+ K 
Sbjct: 383 RRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKL 442

Query: 366 F 366
           F
Sbjct: 443 F 443


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  155 bits (392), Expect = 8e-38
 Identities = 77/206 (37%), Positives = 103/206 (50%), Gaps = 9/206 (4%)

Query: 278 APANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNC 337
           A  +S LG  +   QD  +     +P G     CA C + I G  + ALG+SWHPE F C
Sbjct: 131 ASLDSMLGGLEQELQDLGIAT---VPKGH----CASCQKPIAGKVIHALGQSWHPEHFVC 183

Query: 338 AHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCV 397
            HCK  +    F E  G  YC   Y + F+P C  C   IL +V++A+ QTWH   F C 
Sbjct: 184 THCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCS 243

Query: 398 ACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVC 457
            CG+      FH +D +PYC  D+ A+F   C GC  P+   + +L A+   WH  CFVC
Sbjct: 244 HCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWHPECFVC 301

Query: 458 SVCCESLEGQTFFSKKDKPLCKKHAH 483
             C  S    +FF    +P C+ H H
Sbjct: 302 GDCFTSFSTGSFFELDGRPFCELHYH 327



 Score =  137 bits (346), Expect = 2e-32
 Identities = 64/172 (37%), Positives = 86/172 (50%), Gaps = 2/172 (1%)

Query: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
           +P CA+C   I    L A+ ++WHPE F C+HC       GF E+    YC   +   F+
Sbjct: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           P+CG C R +L   +SA+   WH  CFVC  C        F   DG P+CE  Y+   GT
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           +CHGC  PI      + A+GY +H   FVC+ C   L    F  + DK  C+
Sbjct: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/118 (31%), Positives = 55/118 (46%)

Query: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
           +P C  CN+ +   +L A+   WHPE F C  C  + +   F E  G  +CEL Y     
Sbjct: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425
             C  C + I G  ISA+   +H   FVC  C   +   +F  ++ + YC+  +  LF
Sbjct: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 22/61 (36%), Positives = 32/61 (52%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           +R  +C  C Q I G  + A+G  +HPE F CA C   ++   F E+    YC+ C+ K 
Sbjct: 329 RRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 388

Query: 366 F 366
           F
Sbjct: 389 F 389



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 429 CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485
           C  C+ PI AG + + ALG +WH   FVC+ C E +    FF +     C    H +
Sbjct: 157 CASCQKPI-AGKV-IHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 211


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  155 bits (392), Expect = 8e-38
 Identities = 77/206 (37%), Positives = 103/206 (50%), Gaps = 9/206 (4%)

Query: 278 APANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNC 337
           A  +S LG  +   QD  +     +P G     CA C + I G  + ALG+SWHPE F C
Sbjct: 126 ASLDSMLGGLEQELQDLGIAT---VPKGH----CASCQKPIAGKVIHALGQSWHPEHFVC 178

Query: 338 AHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCV 397
            HCK  +    F E  G  YC   Y + F+P C  C   IL +V++A+ QTWH   F C 
Sbjct: 179 THCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCS 238

Query: 398 ACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVC 457
            CG+      FH +D +PYC  D+ A+F   C GC  P+   + +L A+   WH  CFVC
Sbjct: 239 HCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWHPECFVC 296

Query: 458 SVCCESLEGQTFFSKKDKPLCKKHAH 483
             C  S    +FF    +P C+ H H
Sbjct: 297 GDCFTSFSTGSFFELDGRPFCELHYH 322



 Score =  137 bits (346), Expect = 2e-32
 Identities = 64/172 (37%), Positives = 86/172 (50%), Gaps = 2/172 (1%)

Query: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
           +P CA+C   I    L A+ ++WHPE F C+HC       GF E+    YC   +   F+
Sbjct: 208 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           P+CG C R +L   +SA+   WH  CFVC  C        F   DG P+CE  Y+   GT
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           +CHGC  PI      + A+GY +H   FVC+ C   L    F  + DK  C+
Sbjct: 328 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 377



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/118 (31%), Positives = 55/118 (46%)

Query: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
           +P C  CN+ +   +L A+   WHPE F C  C  + +   F E  G  +CEL Y     
Sbjct: 267 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 326

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425
             C  C + I G  ISA+   +H   FVC  C   +   +F  ++ + YC+  +  LF
Sbjct: 327 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 22/61 (36%), Positives = 32/61 (52%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           +R  +C  C Q I G  + A+G  +HPE F CA C   ++   F E+    YC+ C+ K 
Sbjct: 324 RRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 383

Query: 366 F 366
           F
Sbjct: 384 F 384



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 429 CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485
           C  C+ PI AG + + ALG +WH   FVC+ C E +    FF +     C    H +
Sbjct: 152 CASCQKPI-AGKV-IHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 206


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  147 bits (372), Expect = 2e-35
 Identities = 71/172 (41%), Positives = 90/172 (52%), Gaps = 2/172 (1%)

Query: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
           +P C +CN  I    + AL ++WHPE F CA C       GF E+ G  YC   Y   FA
Sbjct: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           P+CG C R IL   ISAL   WH  CFVC  C  P  N  F   DG+PYCE  Y+   G+
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           +C GC+ PI      + A+   +H   FVC+ C + L   TF  + DKP C+
Sbjct: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416



 Score =  146 bits (369), Expect = 4e-35
 Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C + I G  + A+GK+WHPE F C HC+  +    F E  G  YCE  Y   F+P 
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           C  C   IL +V++AL +TWH   F C  CG       FH +DG+ YC  DY+ +F   C
Sbjct: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 309

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAH 483
            GC   I   + ++ AL   WH  CFVC  C       +FF    +P C+ H H
Sbjct: 310 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 361



 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 39/117 (33%), Positives = 55/117 (47%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I   ++ AL   WHPE F C  C        F E  G  YCE+ Y +    
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425
            C  CQ+ I G  I+A+ + +H   FVC  C K +    F  ++ +PYC+  +  LF
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/61 (34%), Positives = 32/61 (52%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           +R  +C+ C + I G  + A+ K +HPE F CA C   +    F E+    YC+ C+ K 
Sbjct: 363 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 422

Query: 366 F 366
           F
Sbjct: 423 F 423



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485
           +C  C+ PI AG + + A+G TWH   FVC+ C E +  + FF +  +P C+K  H++
Sbjct: 190 VCGACKKPI-AGQV-VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  147 bits (372), Expect = 2e-35
 Identities = 71/172 (41%), Positives = 90/172 (52%), Gaps = 2/172 (1%)

Query: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
           +P C +CN  I    + AL ++WHPE F CA C       GF E+ G  YC   Y   FA
Sbjct: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           P+CG C R IL   ISAL   WH  CFVC  C  P  N  F   DG+PYCE  Y+   G+
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           +C GC+ PI      + A+   +H   FVC+ C + L   TF  + DKP C+
Sbjct: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549



 Score =  146 bits (369), Expect = 4e-35
 Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C + I G  + A+GK+WHPE F C HC+  +    F E  G  YCE  Y   F+P 
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           C  C   IL +V++AL +TWH   F C  CG       FH +DG+ YC  DY+ +F   C
Sbjct: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 442

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAH 483
            GC   I   + ++ AL   WH  CFVC  C       +FF    +P C+ H H
Sbjct: 443 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 494



 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 39/117 (33%), Positives = 55/117 (47%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I   ++ AL   WHPE F C  C        F E  G  YCE+ Y +    
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425
            C  CQ+ I G  I+A+ + +H   FVC  C K +    F  ++ +PYC+  +  LF
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/61 (34%), Positives = 32/61 (52%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           +R  +C+ C + I G  + A+ K +HPE F CA C   +    F E+    YC+ C+ K 
Sbjct: 496 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 555

Query: 366 F 366
           F
Sbjct: 556 F 556



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485
           +C  C+ PI AG + + A+G TWH   FVC+ C E +  + FF +  +P C+K  H++
Sbjct: 323 VCGACKKPI-AGQV-VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  147 bits (372), Expect = 2e-35
 Identities = 71/172 (41%), Positives = 90/172 (52%), Gaps = 2/172 (1%)

Query: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
           +P C +CN  I    + AL ++WHPE F CA C       GF E+ G  YC   Y   FA
Sbjct: 414 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           P+CG C R IL   ISAL   WH  CFVC  C  P  N  F   DG+PYCE  Y+   G+
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           +C GC+ PI      + A+   +H   FVC+ C + L   TF  + DKP C+
Sbjct: 534 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 583



 Score =  146 bits (369), Expect = 4e-35
 Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C + I G  + A+GK+WHPE F C HC+  +    F E  G  YCE  Y   F+P 
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           C  C   IL +V++AL +TWH   F C  CG       FH +DG+ YC  DY+ +F   C
Sbjct: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 476

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAH 483
            GC   I   + ++ AL   WH  CFVC  C       +FF    +P C+ H H
Sbjct: 477 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 528



 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 39/117 (33%), Positives = 55/117 (47%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I   ++ AL   WHPE F C  C        F E  G  YCE+ Y +    
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425
            C  CQ+ I G  I+A+ + +H   FVC  C K +    F  ++ +PYC+  +  LF
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/61 (34%), Positives = 32/61 (52%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           +R  +C+ C + I G  + A+ K +HPE F CA C   +    F E+    YC+ C+ K 
Sbjct: 530 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 589

Query: 366 F 366
           F
Sbjct: 590 F 590



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485
           +C  C+ PI AG + + A+G TWH   FVC+ C E +  + FF +  +P C+K  H++
Sbjct: 357 VCGACKKPI-AGQV-VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 412


>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
          Length = 283

 Score =  131 bits (330), Expect = 1e-30
 Identities = 89/268 (33%), Positives = 132/268 (49%), Gaps = 66/268 (24%)

Query: 3   NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
           +YSV+L GP PWGFRLQGGKDFNMPLTIS +  G KAAQ+ +  GD+V++IDG+N   MT
Sbjct: 2   SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61

Query: 63  HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKPTVTSVCSETSQ-- 109
           HLEAQNKIK  + +L++TLQ++        +A P   P+PV   QK  V S  +   Q  
Sbjct: 62  HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121

Query: 110 ----------------------------------------------ELAEGQRRGSQGDS 123
                                                         +   GQ + +QG  
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQ-AQGSD 180

Query: 124 KQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGT 183
              + P +   V+  +  Y     S    +   ++ ++W  R+   QSRSFRILAQ+TGT
Sbjct: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMTGT 237

Query: 184 EHLKESEADNTKKAN---NSQEPSPQLA 208
           E +++ + +  +++     ++  SP+ A
Sbjct: 238 EFMQDPDEEALRRSRERFETERNSPRFA 265


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  131 bits (329), Expect = 2e-30
 Identities = 69/172 (40%), Positives = 94/172 (54%), Gaps = 4/172 (2%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C+ VI    L+    ++HP+ FNC HC   +      E KG LYC  C++K   P 
Sbjct: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 219

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           CG C+R I G V++AL + WHV  FVC  C KP   +  + + G  YCET Y  LFG +C
Sbjct: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 279

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 480
           + C   IE GD+ + AL   W  +CF CS C   L  +  F + D KP+CK+
Sbjct: 280 YNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKR 329



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 8/178 (4%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I G  + A+  +WHP  F C  C   +A +GFV+  G   C  C+ +  A 
Sbjct: 96  PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155

Query: 369 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 423
                 C RC   I  + +      +H   F C  CGK +      L+ GE YC   +  
Sbjct: 156 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDK 214

Query: 424 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 481
           +   IC  C  PIE     + ALG  WH   FVC+ C +   G   + KK    C+ H
Sbjct: 215 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 270



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P+C  C + I G  + ALGK WH E F CA C+         E+KG  YCE  Y + F  
Sbjct: 218 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 277

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIR-NNVFHLEDGEPYCETDY 421
            C  C   I G+V+SAL + W VSCF C  C   +   N F   D +P C+  Y
Sbjct: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 331



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 370 CGRCQRKI--LGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           C RCQ +      ++++  + +H  CFVC  C +P    +F+  +G  YCE D+  LF  
Sbjct: 37  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96

Query: 428 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
            C  C EF I      ++A+   WH  CF C +C   L    F     + LC+
Sbjct: 97  CCGSCGEFII---GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 146



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 7/146 (4%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G+ +H   F CA C        F E +G  YCE  ++  FAP CG C   I+G VI A+ 
Sbjct: 55  GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 441
             WH  CF C  C   + +  F    G   C   +       L   IC  C   I+   +
Sbjct: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174

Query: 442 FLEALGYTWHDTCFVCSVCCESLEGQ 467
              +  Y  H   F C+ C + L  +
Sbjct: 175 MFRSDAY--HPDHFNCTHCGKELTAE 198



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 365
           +C +C+ VI G  + AL K+W    F+C+ C + +     FVE      C+ CYEKF
Sbjct: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF 334



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 13/57 (22%), Positives = 25/57 (43%)

Query: 423 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           AL   +C  C+      +  + + G  +H+ CFVC+ C        F+  + +  C+
Sbjct: 31  ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  131 bits (329), Expect = 2e-30
 Identities = 69/172 (40%), Positives = 94/172 (54%), Gaps = 4/172 (2%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C+ VI    L+    ++HP+ FNC HC   +      E KG LYC  C++K   P 
Sbjct: 134 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 192

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           CG C+R I G V++AL + WHV  FVC  C KP   +  + + G  YCET Y  LFG +C
Sbjct: 193 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 252

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 480
           + C   IE GD+ + AL   W  +CF CS C   L  +  F + D KP+CK+
Sbjct: 253 YNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKR 302



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 8/178 (4%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I G  + A+  +WHP  F C  C   +A +GFV+  G   C  C+ +  A 
Sbjct: 69  PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 128

Query: 369 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 423
                 C RC   I  + +      +H   F C  CGK +      L+ GE YC   +  
Sbjct: 129 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDK 187

Query: 424 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 481
           +   IC  C  PIE     + ALG  WH   FVC+ C +   G   + KK    C+ H
Sbjct: 188 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 243



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P+C  C + I G  + ALGK WH E F CA C+         E+KG  YCE  Y + F  
Sbjct: 191 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 250

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIR-NNVFHLEDGEPYCETDY 421
            C  C   I G+V+SAL + W VSCF C  C   +   N F   D +P C+  Y
Sbjct: 251 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 304



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 370 CGRCQRKI--LGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           C RCQ +      ++++  + +H  CFVC  C +P    +F+  +G  YCE D+  LF  
Sbjct: 10  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 69

Query: 428 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
            C  C EF I      ++A+   WH  CF C +C   L    F     + LC+
Sbjct: 70  CCGSCGEFII---GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 119



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 7/146 (4%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G+ +H   F CA C        F E +G  YCE  ++  FAP CG C   I+G VI A+ 
Sbjct: 28  GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 87

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 441
             WH  CF C  C   + +  F    G   C   +       L   IC  C   I+   +
Sbjct: 88  NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 147

Query: 442 FLEALGYTWHDTCFVCSVCCESLEGQ 467
              +  Y  H   F C+ C + L  +
Sbjct: 148 MFRSDAY--HPDHFNCTHCGKELTAE 171



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 365
           +C +C+ VI G  + AL K+W    F+C+ C + +     FVE      C+ CYEKF
Sbjct: 251 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF 307



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 13/57 (22%), Positives = 25/57 (43%)

Query: 423 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           AL   +C  C+      +  + + G  +H+ CFVC+ C        F+  + +  C+
Sbjct: 4   ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 60


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  131 bits (329), Expect = 2e-30
 Identities = 69/172 (40%), Positives = 94/172 (54%), Gaps = 4/172 (2%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C+ VI    L+    ++HP+ FNC HC   +      E KG LYC  C++K   P 
Sbjct: 139 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 197

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           CG C+R I G V++AL + WHV  FVC  C KP   +  + + G  YCET Y  LFG +C
Sbjct: 198 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 257

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 480
           + C   IE GD+ + AL   W  +CF CS C   L  +  F + D KP+CK+
Sbjct: 258 YNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKR 307



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 8/178 (4%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I G  + A+  +WHP  F C  C   +A +GFV+  G   C  C+ +  A 
Sbjct: 74  PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 133

Query: 369 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 423
                 C RC   I  + +      +H   F C  CGK +      L+ GE YC   +  
Sbjct: 134 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDK 192

Query: 424 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 481
           +   IC  C  PIE     + ALG  WH   FVC+ C +   G   + KK    C+ H
Sbjct: 193 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 248



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P+C  C + I G  + ALGK WH E F CA C+         E+KG  YCE  Y + F  
Sbjct: 196 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 255

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIR-NNVFHLEDGEPYCETDY 421
            C  C   I G+V+SAL + W VSCF C  C   +   N F   D +P C+  Y
Sbjct: 256 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 309



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 370 CGRCQRKI--LGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           C RCQ +      ++++  + +H  CFVC  C +P    +F+  +G  YCE D+  LF  
Sbjct: 15  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 74

Query: 428 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
            C  C EF I      ++A+   WH  CF C +C   L    F     + LC+
Sbjct: 75  CCGSCGEFII---GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 124



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 7/146 (4%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G+ +H   F CA C        F E +G  YCE  ++  FAP CG C   I+G VI A+ 
Sbjct: 33  GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 92

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 441
             WH  CF C  C   + +  F    G   C   +       L   IC  C   I+   +
Sbjct: 93  NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 152

Query: 442 FLEALGYTWHDTCFVCSVCCESLEGQ 467
              +  Y  H   F C+ C + L  +
Sbjct: 153 MFRSDAY--HPDHFNCTHCGKELTAE 176



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 365
           +C +C+ VI G  + AL K+W    F+C+ C + +     FVE      C+ CYEKF
Sbjct: 256 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF 312



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 13/57 (22%), Positives = 25/57 (43%)

Query: 423 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           AL   +C  C+      +  + + G  +H+ CFVC+ C        F+  + +  C+
Sbjct: 9   ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 65


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  131 bits (329), Expect = 2e-30
 Identities = 69/172 (40%), Positives = 94/172 (54%), Gaps = 4/172 (2%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C+ VI    L+    ++HP+ FNC HC   +      E KG LYC  C++K   P 
Sbjct: 163 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 221

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           CG C+R I G V++AL + WHV  FVC  C KP   +  + + G  YCET Y  LFG +C
Sbjct: 222 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 281

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 480
           + C   IE GD+ + AL   W  +CF CS C   L  +  F + D KP+CK+
Sbjct: 282 YNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKR 331



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 8/178 (4%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I G  + A+  +WHP  F C  C   +A +GFV+  G   C  C+ +  A 
Sbjct: 98  PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 157

Query: 369 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 423
                 C RC   I  + +      +H   F C  CGK +      L+ GE YC   +  
Sbjct: 158 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDK 216

Query: 424 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 481
           +   IC  C  PIE     + ALG  WH   FVC+ C +   G   + KK    C+ H
Sbjct: 217 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 272



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P+C  C + I G  + ALGK WH E F CA C+         E+KG  YCE  Y + F  
Sbjct: 220 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 279

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIR-NNVFHLEDGEPYCETDY 421
            C  C   I G+V+SAL + W VSCF C  C   +   N F   D +P C+  Y
Sbjct: 280 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 333



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 370 CGRCQRKI--LGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           C RCQ +      ++++  + +H  CFVC  C +P    +F+  +G  YCE D+  LF  
Sbjct: 39  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 98

Query: 428 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
            C  C EF I      ++A+   WH  CF C +C   L    F     + LC+
Sbjct: 99  CCGSCGEFII---GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 148



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 7/146 (4%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G+ +H   F CA C        F E +G  YCE  ++  FAP CG C   I+G VI A+ 
Sbjct: 57  GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 116

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 441
             WH  CF C  C   + +  F    G   C   +       L   IC  C   I+   +
Sbjct: 117 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 176

Query: 442 FLEALGYTWHDTCFVCSVCCESLEGQ 467
              +  Y  H   F C+ C + L  +
Sbjct: 177 MFRSDAY--HPDHFNCTHCGKELTAE 200



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 365
           +C +C+ VI G  + AL K+W    F+C+ C + +     FVE      C+ CYEKF
Sbjct: 280 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF 336



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 13/57 (22%), Positives = 25/57 (43%)

Query: 423 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           AL   +C  C+      +  + + G  +H+ CFVC+ C        F+  + +  C+
Sbjct: 33  ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 89


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  127 bits (319), Expect = 2e-29
 Identities = 68/172 (39%), Positives = 91/172 (52%), Gaps = 4/172 (2%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
           +C  C+ +I    L+     +HP+ FNCA+C   +      E KG LYC  C++K   P 
Sbjct: 134 ICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELT-ADARELKGELYCLPCHDKMGVPI 192

Query: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
           CG C+R I G V++A+ + WHV  FVC  C KP   +  +   G  YCET Y  LFG +C
Sbjct: 193 CGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVC 252

Query: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 480
             C   IE GD+ + AL   W   CF CS C   L  +  F + D KP+CKK
Sbjct: 253 FHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKK 302



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 55/178 (30%), Positives = 79/178 (44%), Gaps = 8/178 (4%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P C  C + I G  + A+  SWHPE F C  C+  +A IGFV+  G   C  C+ +  A 
Sbjct: 69  PCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKAR 128

Query: 369 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 423
                 C +C   I  + +      +H   F C  CGK +  +   L+ GE YC   +  
Sbjct: 129 GLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDK 187

Query: 424 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 481
           +   IC  C  PIE     + A+G  WH   FVC+ C +   G   + +K    C+ H
Sbjct: 188 MGVPICGACRRPIEG--RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)

Query: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           P+C  C + I G  + A+GK WH E F CA C+         E KG  YCE  Y + F  
Sbjct: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250

Query: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACG-KPIRNNVFHLEDGEPYCETDY 421
            C  C R I G+V+SAL + W V+CF C  C  K    N F   D +P C+  Y
Sbjct: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304



 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 35/113 (30%), Positives = 55/113 (48%), Gaps = 6/113 (5%)

Query: 370 CGRCQRKILG--EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           C RC+       +++++  + +H  CFVC  C +     +F+  +G  YCE D+  LF  
Sbjct: 10  CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAP 69

Query: 428 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
            CH C EF I      ++A+  +WH  CF C +C E L    F     + LC+
Sbjct: 70  CCHQCGEFII---GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 119



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 42/143 (29%), Positives = 61/143 (42%), Gaps = 7/143 (4%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G+ +H + F CA C        F E +G  YCE  ++  FAP C +C   I+G VI A+ 
Sbjct: 28  GELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMN 87

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 441
            +WH  CF C  C + + +  F    G   C   +       L   IC  C   I+   +
Sbjct: 88  NSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPL 147

Query: 442 FLEALGYTWHDTCFVCSVCCESL 464
             +   Y  H   F C+ C + L
Sbjct: 148 IFKNDPY--HPDHFNCANCGKEL 168



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 365
           +C HCN+VI G  + AL K+W    F C+ C   +     FVE      C+ CYEKF
Sbjct: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 13/57 (22%), Positives = 25/57 (43%)

Query: 423 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           AL    C  C+      +  + + G  +H+ CFVC+ C +      F+  + +  C+
Sbjct: 4   ALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  119 bits (299), Expect = 5e-27
 Identities = 56/155 (36%), Positives = 75/155 (48%), Gaps = 2/155 (1%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G++WH   F C+ C+  +    FV +KGA YC  CYE  FAP C RC + +    ++   
Sbjct: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444
           Q WH  C VC  C  P+    F   D +PYC   +  LF   C  C+ PI    G  ++ 
Sbjct: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238

Query: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
                WH  CF C+ C  SL GQ F    D+ LC+
Sbjct: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273



 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 45/149 (30%), Positives = 69/149 (46%), Gaps = 4/149 (2%)

Query: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISAL---KQTW 389
           E F+CA C  ++    +++     YC  CY+  FA  C  CQ+ ++G     L    + +
Sbjct: 3   ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQ-LIGHDSRELFYEDRHF 61

Query: 390 HVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYT 449
           H  CF C  C + + +  F  +D E  C   Y + F + C  C   +  G   LE  G T
Sbjct: 62  HEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQT 121

Query: 450 WHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
           WH+ CF+CS C + L  ++F   K    C
Sbjct: 122 WHEHCFLCSGCEQPLGSRSFVPDKGAHYC 150



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 50/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)

Query: 311 CAHCNQVIRGPF--LVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
           CA C Q+I      L    + +H   F C  C+ ++A   F  +   L C  CY   F+ 
Sbjct: 40  CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99

Query: 369 ECGRCQRKIL--GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
           +C  C   ++     +    QTWH  CF+C  C +P+ +  F  + G  YC   Y   F 
Sbjct: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159

Query: 427 TICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
             C  C   +  G +        WH  C VC+ C   L GQ F S+ + P C
Sbjct: 160 PRCARCSKTLTQGGVTYR--DQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 16/131 (12%)

Query: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
           K  P CA C++ +    +    + WH E   C  C+  +A   F       YC  C+ + 
Sbjct: 157 KFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGEL 216

Query: 366 FAPECGRCQRKIL----GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY 421
           FAP+C  C+R I+    G+ +S   + WH +CF C  C   +    F + DG+       
Sbjct: 217 FAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGF-VPDGDQ------ 269

Query: 422 YALFGTICHGC 432
                 +C GC
Sbjct: 270 -----VLCQGC 275


>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
          Length = 330

 Score =  117 bits (293), Expect = 2e-26
 Identities = 56/98 (57%), Positives = 73/98 (74%), Gaps = 3/98 (3%)

Query: 3   NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
           +YSV+L GP PWGFRLQGGKDFNMPLTIS +  G KAAQ+ +  GD+V++IDG+N   MT
Sbjct: 2   SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61

Query: 63  HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTV 100
           HLEAQNKIK  + +L++TLQ++    +P P+    P V
Sbjct: 62  HLEAQNKIKSASYNLSLTLQKSK---RPIPISTTAPPV 96



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 20/61 (32%), Positives = 39/61 (63%), Gaps = 3/61 (4%)

Query: 151 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAN---NSQEPSPQL 207
           S+ +  ++ ++W  R+   QSRSFRILAQ+TGTE +++ + +  +++     ++  SP+ 
Sbjct: 252 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRF 311

Query: 208 A 208
           A
Sbjct: 312 A 312


>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
          Length = 329

 Score =  114 bits (284), Expect = 3e-25
 Identities = 105/359 (29%), Positives = 144/359 (40%), Gaps = 51/359 (14%)

Query: 1   MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
           M+   + L GP PWGFRL GGKDF  PL IS +  G KAA AN+ IGDV+ +IDG N   
Sbjct: 1   MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN 60

Query: 61  MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQ 120
           MTHLEAQN+IKGCT +L +T+ R+          V  P VT           EG+R    
Sbjct: 61  MTHLEAQNRIKGCTDNLTLTVARSEH-------KVWSPLVTE----------EGKRH--- 100

Query: 121 GDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQI 180
                   P + ++     E  H+ +  + S            P + TT   +  I  Q 
Sbjct: 101 --------PYKMNLASEPQEVLHIGSAHNRSAMPFTAS-----PASSTT---ARVITNQY 144

Query: 181 TGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAF 240
                L  SE  N    NN+ E   + A+S     S P     P S    +     +  +
Sbjct: 145 NNPAGLYSSE--NISNFNNALE--SKTAASGVEANSRPLDHAQPPS---SLVIDKESEVY 197

Query: 241 KPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAE 300
           K +     +  P    P Q   ++  +      S      N   G        T V  A 
Sbjct: 198 KMLQEKQELNEP----PKQS--TSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKV--AA 249

Query: 301 HIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCE 359
            I   ++ PMC  C   I G F+    +  HPE + C  C   +   G    +  +YCE
Sbjct: 250 SIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCE 308



 Score = 35.8 bits (81), Expect = 0.090
 Identities = 14/51 (27%), Positives = 23/51 (45%)

Query: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCE 418
           P C +C   I+G  +    +  H  C+VC  CG  ++       + + YCE
Sbjct: 258 PMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCE 308



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 12/32 (37%), Positives = 20/32 (62%)

Query: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLCKKHA 482
           H  C+VC+ C  +L+ +  F  +D+  C+KHA
Sbjct: 280 HPECYVCTDCGTNLKQKGHFFVEDQIYCEKHA 311


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score =  108 bits (269), Expect = 1e-23
 Identities = 58/183 (31%), Positives = 91/183 (49%), Gaps = 8/183 (4%)

Query: 285 GQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVI--RGPFLVALGKSWHPEEFNCAHCKN 342
           G  +P +++     AE +  G  T +CA C++ +  R   + A+ + +H + F C  C+ 
Sbjct: 157 GPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRR 216

Query: 343 TMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKP 402
            +A   F ++ G   CE CY+      CG+C   +   +I AL Q +H SCF CV C + 
Sbjct: 217 QLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARC 275

Query: 403 IRNNVFHL-EDGEPYCETDYYALFGTICHGCEFPI---EAGDMF-LEALGYTWHDTCFVC 457
           I +  F L    E YC  D+Y  F  +C  CE PI   +  D F +E +G  +H+ C+ C
Sbjct: 276 IGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRC 335

Query: 458 SVC 460
             C
Sbjct: 336 EDC 338



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)

Query: 370 CGRCQRKILGE--VISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
           C  C + +      + A+K+ +H  CF C  C + +    F+ +DG P CE  Y      
Sbjct: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 242

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTF 469
            C  C   +   D  + ALG  +H +CF C  C   +  ++F
Sbjct: 243 -CGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESF 281



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 18/52 (34%), Positives = 28/52 (53%)

Query: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
           IC  C   +   ++ +EA+   +H  CF C  C   L GQ+F+ K  +PLC+
Sbjct: 182 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  105 bits (262), Expect = 9e-23
 Identities = 51/154 (33%), Positives = 73/154 (47%), Gaps = 2/154 (1%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G SWH   F C  C+  +    F+ +    +C  CYEK  A +C +C++ I    ++  +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444
           Q WH  CFVC AC K +    F   D   YC   +  L+   C GC  PI    G  ++ 
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238

Query: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
                WH+ CF C  C  SL G+ F +++D  LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 4/153 (2%)

Query: 328 KSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL--GEVISAL 385
           + WH   F+C+ C+N++    F  ++  L C  CY   ++ +C  C++ I+     +   
Sbjct: 59  RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118

Query: 386 KQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEA 445
             +WH +CF+C  C +PI    F  +D + +C   Y       C  C+ PI  G +    
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 446 LGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
               WH  CFVC+ C + L GQ F ++ D   C
Sbjct: 179 --QPWHKECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 7/157 (4%)

Query: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 390
           E F+C HC  ++    ++  + + YC +C+E  FA  C  C + I  +   +S   + WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450
            +CF C  C   + +  F  ++ +  C   Y   + + C  C+  I  G   +E  G +W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC-----KKHA 482
           H+TCF+C  C + +  ++F  K ++  C     K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 311 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPEC 370
           C  C + I    +    + WH E F C  C+  ++   F       YC  C+   +A +C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221

Query: 371 GRCQRKILG----EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 417
             C   I G    + IS  ++ WH  CF C  C   +    F  E  +  C
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 13/66 (19%)

Query: 311 CAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
           CA C   I G     ++    + WH + FNC  C  ++   GF+ E+  + C        
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC-------- 272

Query: 367 APECGR 372
            P+CG+
Sbjct: 273 -PDCGK 277


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  105 bits (262), Expect = 9e-23
 Identities = 51/154 (33%), Positives = 73/154 (47%), Gaps = 2/154 (1%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G SWH   F C  C+  +    F+ +    +C  CYEK  A +C +C++ I    ++  +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444
           Q WH  CFVC AC K +    F   D   YC   +  L+   C GC  PI    G  ++ 
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238

Query: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
                WH+ CF C  C  SL G+ F +++D  LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 4/153 (2%)

Query: 328 KSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL--GEVISAL 385
           + WH   F+C+ C+N++    F  ++  L C  CY   ++ +C  C++ I+     +   
Sbjct: 59  RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118

Query: 386 KQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEA 445
             +WH +CF+C  C +PI    F  +D + +C   Y       C  C+ PI  G +    
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 446 LGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
               WH  CFVC+ C + L GQ F ++ D   C
Sbjct: 179 --QPWHKECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 7/157 (4%)

Query: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 390
           E F+C HC  ++    ++  + + YC +C+E  FA  C  C + I  +   +S   + WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450
            +CF C  C   + +  F  ++ +  C   Y   + + C  C+  I  G   +E  G +W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC-----KKHA 482
           H+TCF+C  C + +  ++F  K ++  C     K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 311 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPEC 370
           C  C + I    +    + WH E F C  C+  ++   F       YC  C+   +A +C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221

Query: 371 GRCQRKILG----EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 417
             C   I G    + IS  ++ WH  CF C  C   +    F  E  +  C
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 13/66 (19%)

Query: 311 CAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
           CA C   I G     ++    + WH + FNC  C  ++   GF+ E+  + C        
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC-------- 272

Query: 367 APECGR 372
            P+CG+
Sbjct: 273 -PDCGK 277


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  105 bits (262), Expect = 9e-23
 Identities = 51/154 (33%), Positives = 73/154 (47%), Gaps = 2/154 (1%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G SWH   F C  C+  +    F+ +    +C  CYEK  A +C +C++ I    ++  +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444
           Q WH  CFVC AC K +    F   D   YC   +  L+   C GC  PI    G  ++ 
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238

Query: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
                WH+ CF C  C  SL G+ F +++D  LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 4/153 (2%)

Query: 328 KSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL--GEVISAL 385
           + WH   F+C+ C+N++    F  ++  L C  CY   ++ +C  C++ I+     +   
Sbjct: 59  RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118

Query: 386 KQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEA 445
             +WH +CF+C  C +PI    F  +D + +C   Y       C  C+ PI  G +    
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 446 LGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
               WH  CFVC+ C + L GQ F ++ D   C
Sbjct: 179 --QPWHKECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 7/157 (4%)

Query: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 390
           E F+C HC  ++    ++  + + YC +C+E  FA  C  C + I  +   +S   + WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450
            +CF C  C   + +  F  ++ +  C   Y   + + C  C+  I  G   +E  G +W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC-----KKHA 482
           H+TCF+C  C + +  ++F  K ++  C     K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 311 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPEC 370
           C  C + I    +    + WH E F C  C+  ++   F       YC  C+   +A +C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221

Query: 371 GRCQRKILG----EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 417
             C   I G    + IS  ++ WH  CF C  C   +    F  E  +  C
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 13/66 (19%)

Query: 311 CAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
           CA C   I G     ++    + WH + FNC  C  ++   GF+ E+  + C        
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC-------- 272

Query: 367 APECGR 372
            P+CG+
Sbjct: 273 -PDCGK 277


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  105 bits (262), Expect = 9e-23
 Identities = 51/154 (33%), Positives = 73/154 (47%), Gaps = 2/154 (1%)

Query: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
           G SWH   F C  C+  +    F+ +    +C  CYEK  A +C +C++ I    ++  +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444
           Q WH  CFVC AC K +    F   D   YC   +  L+   C GC  PI    G  ++ 
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238

Query: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
                WH+ CF C  C  SL G+ F +++D  LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 4/153 (2%)

Query: 328 KSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL--GEVISAL 385
           + WH   F+C+ C+N++    F  ++  L C  CY   ++ +C  C++ I+     +   
Sbjct: 59  RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118

Query: 386 KQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEA 445
             +WH +CF+C  C +PI    F  +D + +C   Y       C  C+ PI  G +    
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 446 LGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
               WH  CFVC+ C + L GQ F ++ D   C
Sbjct: 179 --QPWHKECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 7/157 (4%)

Query: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 390
           E F+C HC  ++    ++  + + YC +C+E  FA  C  C + I  +   +S   + WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450
            +CF C  C   + +  F  ++ +  C   Y   + + C  C+  I  G   +E  G +W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC-----KKHA 482
           H+TCF+C  C + +  ++F  K ++  C     K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 311 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPEC 370
           C  C + I    +    + WH E F C  C+  ++   F       YC  C+   +A +C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221

Query: 371 GRCQRKILG----EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 417
             C   I G    + IS  ++ WH  CF C  C   +    F  E  +  C
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 13/66 (19%)

Query: 311 CAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366
           CA C   I G     ++    + WH + FNC  C  ++   GF+ E+  + C        
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC-------- 272

Query: 367 APECGR 372
            P+CG+
Sbjct: 273 -PDCGK 277


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,901,408
Number of Sequences: 37866
Number of extensions: 1054159
Number of successful extensions: 5444
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 166
Number of HSP's that attempted gapping in prelim test: 4250
Number of HSP's gapped (non-prelim): 996
length of query: 487
length of database: 18,247,518
effective HSP length: 106
effective length of query: 381
effective length of database: 14,233,722
effective search space: 5423048082
effective search space used: 5423048082
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.