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Search of human proteins with 197245440
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197245440 hypothetical protein LOC23285 [Homo sapiens]
(1354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197245440 hypothetical protein LOC23285 [Homo sapiens] 2689 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 82 5e-15
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 60 1e-08
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 56 2e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 54 1e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 54 1e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 2e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 53 2e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 52 3e-06
gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 52 5e-06
gi|87299628 biorientation of chromosomes in cell division 1-like... 50 2e-05
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 49 3e-05
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 48 6e-05
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 47 1e-04
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 47 1e-04
gi|217330641 IWS1 homolog [Homo sapiens] 46 3e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 46 3e-04
gi|28559039 mediator complex subunit 1 [Homo sapiens] 45 4e-04
gi|161016767 mucin 21 [Homo sapiens] 45 4e-04
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 45 5e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 44 0.001
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 44 0.001
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 43 0.002
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 43 0.002
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 43 0.002
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 42 0.003
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 42 0.003
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 42 0.003
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 42 0.004
>gi|197245440 hypothetical protein LOC23285 [Homo sapiens]
Length = 1354
Score = 2689 bits (6970), Expect = 0.0
Identities = 1354/1354 (100%), Positives = 1354/1354 (100%)
Query: 1 MSSTADLLDTILKAIEENITTENSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFL 60
MSSTADLLDTILKAIEENITTENSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFL
Sbjct: 1 MSSTADLLDTILKAIEENITTENSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFL 60
Query: 61 VQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDSGDIKI 120
VQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDSGDIKI
Sbjct: 61 VQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDSGDIKI 120
Query: 121 KSWRGNNKKECWSYLSTNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASK 180
KSWRGNNKKECWSYLSTNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASK
Sbjct: 121 KSWRGNNKKECWSYLSTNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASK 180
Query: 181 ITKELKTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNG 240
ITKELKTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNG
Sbjct: 181 ITKELKTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNG 240
Query: 241 KGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFSI 300
KGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFSI
Sbjct: 241 KGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFSI 300
Query: 301 STECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGT 360
STECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGT
Sbjct: 301 STECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGT 360
Query: 361 SNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTK 420
SNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTK
Sbjct: 361 SNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTK 420
Query: 421 TQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVA 480
TQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVA
Sbjct: 421 TQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVA 480
Query: 481 MPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNN 540
MPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNN
Sbjct: 481 MPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNN 540
Query: 541 KDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSL 600
KDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSL
Sbjct: 541 KDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSL 600
Query: 601 KHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPN 660
KHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPN
Sbjct: 601 KHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPN 660
Query: 661 ENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLN 720
ENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLN
Sbjct: 661 ENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLN 720
Query: 721 SAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETS 780
SAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETS
Sbjct: 721 SAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETS 780
Query: 781 ESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDD 840
ESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDD
Sbjct: 781 ESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDD 840
Query: 841 GSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTS 900
GSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTS
Sbjct: 841 GSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTS 900
Query: 901 DDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAENVAEN 960
DDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAENVAEN
Sbjct: 901 DDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAENVAEN 960
Query: 961 FSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTP 1020
FSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTP
Sbjct: 961 FSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTP 1020
Query: 1021 FQASVDSFSPSDVFDGISHEHHGRTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLS 1080
FQASVDSFSPSDVFDGISHEHHGRTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLS
Sbjct: 1021 FQASVDSFSPSDVFDGISHEHHGRTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLS 1080
Query: 1081 SIDSSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVK 1140
SIDSSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVK
Sbjct: 1081 SIDSSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVK 1140
Query: 1141 SQERPCHLDLHQREPNSDIPKNSSTKSLDSFRSQVLPQEGPVKESHSTTTEKANIALSAG 1200
SQERPCHLDLHQREPNSDIPKNSSTKSLDSFRSQVLPQEGPVKESHSTTTEKANIALSAG
Sbjct: 1141 SQERPCHLDLHQREPNSDIPKNSSTKSLDSFRSQVLPQEGPVKESHSTTTEKANIALSAG 1200
Query: 1201 DIDDCDTLAQTRMYDHRPSKTLSPIYEMDVIEAFEQKVESETHVTDMDFEDDQHFAKQDW 1260
DIDDCDTLAQTRMYDHRPSKTLSPIYEMDVIEAFEQKVESETHVTDMDFEDDQHFAKQDW
Sbjct: 1201 DIDDCDTLAQTRMYDHRPSKTLSPIYEMDVIEAFEQKVESETHVTDMDFEDDQHFAKQDW 1260
Query: 1261 TLLKQLLSEQDSNLDVTNSVPEDLSLAQYLINQTLLLARDSSKPQGITHIDTLNRWSELT 1320
TLLKQLLSEQDSNLDVTNSVPEDLSLAQYLINQTLLLARDSSKPQGITHIDTLNRWSELT
Sbjct: 1261 TLLKQLLSEQDSNLDVTNSVPEDLSLAQYLINQTLLLARDSSKPQGITHIDTLNRWSELT 1320
Query: 1321 SPLDSSASITMASFSSEDCSPQGEWTILELETQH 1354
SPLDSSASITMASFSSEDCSPQGEWTILELETQH
Sbjct: 1321 SPLDSSASITMASFSSEDCSPQGEWTILELETQH 1354
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 81.6 bits (200), Expect = 5e-15
Identities = 148/865 (17%), Positives = 291/865 (33%), Gaps = 55/865 (6%)
Query: 113 SDSGDIKIKSWRGNNKKECWSYLSTNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEK 172
S GD S N + S N + D S S S +K + DD
Sbjct: 459 SMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDD---S 515
Query: 173 DGTKIASKITKELKTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAAT 232
D T + N K K+++ D ++ + + S + ++ +
Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575
Query: 233 GQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRST 292
+ + + + + + + + + DS S S S+
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD-SS 634
Query: 293 DSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRP 352
DS + S + +N + + S + DS +S NS+ + S
Sbjct: 635 DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694
Query: 353 VSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTK 412
S + + + S ++ ++S S S + S+ + + +
Sbjct: 695 SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754
Query: 413 STPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALP 472
S+ S+ + +S +S SS SS SD N + +++ + +
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814
Query: 473 KVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMF 532
++ + N S ++ N+ DS S + S + + + S
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDS-------SDSSDGSDSDSSNRSDSSNSSDS 867
Query: 533 HDVRDNNNKDSVSEQKPHKPLINLA-----SEISDAEALQSSCRPDPQKPLNDQEKEKLA 587
D D++N S+ N + S SD+++ SS D N + + +
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927
Query: 588 LECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFY 647
N + D S + +D D++N S SD+ NS
Sbjct: 928 NSSDNSNSSDSSNSSD-------------------SSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 648 STTALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDV 707
S SN +++S +SN DS+ + SD N D++ S D
Sbjct: 969 SD-------SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 708 SLCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQ 767
S + + +N + +S D + S S+ S + ++ SD S S
Sbjct: 1022 SNSS-DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 768 LSEK-------NSPKNMETSESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTS 820
SE NS + ++S+S +S ++ ++ + S+ +S +S S +++
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140
Query: 821 SDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLR 880
S D SE D+ S D S+D S + SSD+S DS+
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS-----DSSDS 1195
Query: 881 IEVKMKKQSNNDLFQVNSTSDDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQV 940
+ S++ +S+ + S + S ++ + +
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255
Query: 941 SSSADETEDERSEAENVAENFSISN 965
S S+D T D E+++ +++ + +N
Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNN 1280
Score = 79.3 bits (194), Expect = 2e-14
Identities = 142/775 (18%), Positives = 266/775 (34%), Gaps = 81/775 (10%)
Query: 78 TDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDSGDIKIKSWRGNNKKECWSYLST 137
+ D ++ D D S S SDS D K S +K E S S
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS----SKSESDSSDSD 637
Query: 138 NKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASKITKELKTGGKNVSGKPK 197
+K SD + +S + +S N + D D + +S
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS----------------- 680
Query: 198 TVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVRNQEGQISGARPKV 257
+ + + +++ D + N S E S ++ ++ + + + + + S +
Sbjct: 681 SDSSNSSDSSDSSDSSNSS-----ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735
Query: 258 LTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEE 317
+ N DS S + SS S+DSS + S S++ D + S++
Sbjct: 736 DSSN--------------SSDSSDSSDSSNSSDSSDSS-DSSNSSDSSDSSDSSDSSDSS 780
Query: 318 KPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSV 377
S S S NS DS +S + S ++ +S+ + + + N+S
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS- 839
Query: 378 LKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVS 437
S S + R S+ + + + S+ S+ + ES NS SS S
Sbjct: 840 --DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 438 SRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNK 497
S SD + + +++ + + N S E+ N+
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSS---------------------------NSSDSSESSNSS 930
Query: 498 DSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLA 557
D+ + S +++ S D D+N+ DS +
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN--------S 982
Query: 558 SEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETK 617
S+ SD+ S +D + + N S S S S
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 618 FPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDLDSTSA 677
+ +D D++N S SD+ +S S ++ S +++S +SN DS+ +
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 678 GQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTI 737
SD + D++ S D S + + +N + +S + +
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 738 PSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKN-SPKNMETSESPESHETPETPFVGH 796
S SD S + ++ SD S S S+ + S + ++S+S +S ++ ++
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221
Query: 797 WNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCG 851
+ S+ ES +S S ++ S + S+ D+ S D SK G
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276
Score = 63.9 bits (154), Expect = 1e-09
Identities = 111/561 (19%), Positives = 200/561 (35%), Gaps = 68/561 (12%)
Query: 657 SNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTN 716
SN N+++ N D +S+S G SD G +K + + S N +N
Sbjct: 471 SNGNDDA---NSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSN 527
Query: 717 GTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKN 776
G N+ +D +G SD S D D +++S SS S+ NS +
Sbjct: 528 GNGNNGNDDNDKSDSGKGK------SDSS--DSDSSDSSNSSDSSDSSDSDSSDSNSSSD 579
Query: 777 METSESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGS 836
++S+S S +S +SD+ ++ SSD D+ S
Sbjct: 580 SDSSDSDSS----------------------DSSDSDSSDSSNSSDSS-------DSSDS 610
Query: 837 QDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQV 896
D S+D SK + +S SD+S + K S+ ++D
Sbjct: 611 SDSSDSSDSSDSKSDS-------SKSESDSSDSDS-KSDSSDSNSSDSSDNSDSSDSSNS 662
Query: 897 NSTSDDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAEN 956
+++SD + S S +S + + S + S S+D ++ + S++ +
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS-----NSSESSDSSDSSDSDSSDSSD 717
Query: 957 VAENFSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGE 1016
+ + S + + + D++++ S+ S D + S +
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Query: 1017 VHTPFQASVDSFSPSDVFDGISHEHHGRTCYSRFSRESED----------NILECKQNKG 1066
+ S DS + SD D + + S S +S D N + +
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837
Query: 1067 NSVCKNESTVLDLSSIDSSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNNGSNVEN 1126
+S + S D S DSS ++ S S+ ++ SS S D +N S+ +
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS-----SDSSDSNESSNSS 892
Query: 1127 DIQQRSKFLDSDVKSQERPCHLDLHQREPNSDIPKNSSTKSLDSFRSQVLPQEGPVKESH 1186
D S DSD +S NSS S S S S+
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 1187 STTTEKANIALSAGDIDDCDT 1207
S+ + ++ + ++ D D ++
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNS 973
Score = 35.0 bits (79), Expect = 0.49
Identities = 98/544 (18%), Positives = 175/544 (32%), Gaps = 63/544 (11%)
Query: 691 GRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDED 750
G++D + S + + +PE N DK SK IP + D
Sbjct: 286 GKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQ 345
Query: 751 K-------------------HATADSDVSSKCFSGQLS-EKNSPKNMETSESPESHETPE 790
K HA S G S +N K + + +
Sbjct: 346 KLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQH 405
Query: 791 TPFVGHWNLSTG--VLH-----QRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSN 843
+G N+ T V++ Q+ P + G + T SD S+ YD S D D +
Sbjct: 406 GMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDS---NSDGYD---SYDFDDKS 459
Query: 844 DRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDE 903
+G +SSD S + +S+ + N+D + N D
Sbjct: 460 MQGDDP------------NSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDS 507
Query: 904 IPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAENVAENFSI 963
+ + S S +S N G+ + D +D ++ + S++ N +++
Sbjct: 508 KGAEDDDSDSTSDTNNSDSNGNGNNGNDD-NDKSDSGKGKSDSSDSDSSDSSNSSDSSDS 566
Query: 964 SNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTPFQA 1023
S+ D++++ S + S D + S + +
Sbjct: 567 SD--------------SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612
Query: 1024 SVDSFSPSDVFDGISHEHHGRTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLSSID 1083
S DS SD S + S S+ N + N +S N S D S
Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 1084 SSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQE 1143
S + S ++ ++ D S + + ++ + ++ S DSD +
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 1144 RPCHLDLHQREPNSDIPKNS--STKSLDSFRSQVLPQEGPVKE-SHSTTTEKANIALSAG 1200
+S NS S+ S DS S + S S+ + +N + ++
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 1201 DIDD 1204
D D
Sbjct: 793 DSSD 796
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 60.5 bits (145), Expect = 1e-08
Identities = 102/492 (20%), Positives = 175/492 (35%), Gaps = 78/492 (15%)
Query: 288 SSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVA 347
SS +DS E S S +EP ++ S E E P +K + N ++ V V+
Sbjct: 436 SSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNK--------WQLDNWLNKVNPHKVS 487
Query: 348 IKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAA 407
S S + + KK EQ T NS K S P + G +
Sbjct: 488 PASSVDSNIPSSQGYKKEGREQGT--GNSYTDTSGPKETSSATPGR--DSKTIQKGSESG 543
Query: 408 QQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTE------------ 455
+ R KS + + TQ K+ ++ + K++ T +
Sbjct: 544 RGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKA 603
Query: 456 -KQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETL-------NNKDSKQKMPPGQ 507
+ ++ +K+ + P+ A+ S+K + ++ D + +PP
Sbjct: 604 ATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSS 663
Query: 508 VISKTQPSSQRPLK-----HETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLI-----NLA 557
K S++ P+K E S ++ MF + + +SE PLI NL
Sbjct: 664 QTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLL 723
Query: 558 SEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETK 617
+ I P KP + E K E +N+ + KH E+++ +K K
Sbjct: 724 TRI-------------PGKPYKETEPPK--GEKKNVPE-----KHTREAQKQASEKVSNK 763
Query: 618 FP-NHKETDDCDAA----------NICCHSVGSDNVNSKFYSTTALKYMVSNPNENSLNS 666
HK DD A+ N H S+ +SK S K ++ +P
Sbjct: 764 GKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSK-QSAAKEKDLLPSP----AGP 818
Query: 667 NPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDK 726
P D + + IS + ++NK++S S ++T G +S+ ++
Sbjct: 819 VPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV 878
Query: 727 KSKVPVEGLTIP 738
K K P P
Sbjct: 879 KEKAPSSSSNCP 890
Score = 39.7 bits (91), Expect = 0.020
Identities = 178/925 (19%), Positives = 319/925 (34%), Gaps = 129/925 (13%)
Query: 313 STEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDTN 372
+++E+K S S + +M D VAI V + SN ++
Sbjct: 42 TSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGG 101
Query: 373 VNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSV 432
+ S K + G + Q+ + G +G ++ QRT + S+ T + G + + +
Sbjct: 102 SHQS--SKWTPVGPAPSTSQSQKRSSGLQSGHSS--QRTSAGSSSGTNSSGQRHDRESYN 157
Query: 433 KSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGE 492
S SSR+ ++ + +H+ + K + V ++++ + + ++ +
Sbjct: 158 NSGSSSRKKGQHGS--EHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRD 215
Query: 493 TLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKP 552
N DS ++P TQ + S +QK + VR + ++S+ +
Sbjct: 216 PDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAY-VRPMDGQESMEPK----- 269
Query: 553 LINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLD 612
L+SE +++ +S KP + KL + Q LD S ++ C+D
Sbjct: 270 ---LSSEHYSSQSHGNSMTE--LKPSSKAHLTKLKIPSQ---PLDASASGDVS----CVD 317
Query: 613 KSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDL 672
+ K H A + C + S KF T + NP
Sbjct: 318 EI-LKEMTHSWPPPLTAIHTPCKTEPS-----KFPFPTKESQQSNFGTGEQKRYNP---- 367
Query: 673 DSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPV 732
TS G +++ KD K SS + + C+ T S E
Sbjct: 368 SKTSNGH-------QSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHN--- 417
Query: 733 EGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETSESPESHETPETP 792
S+ +D S D H+ ++S S S S + S SPE PE P
Sbjct: 418 ------SEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPE----PEPP 467
Query: 793 FVGHWNLS---TGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDD---------- 839
W L V + SP S S SS K + G S D
Sbjct: 468 PTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSA 527
Query: 840 -DGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNS 898
G + + I K G+ + ST + + + K + ++ S
Sbjct: 528 TPGRDSKTIQK-GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586
Query: 899 TSDDEIPRKRPEIWSRSAIVHSR------ERENIPRGSVQ-----FAQEIDQVSSSADET 947
+ ++ P ++A SR E ++ PR + + + Q S ET
Sbjct: 587 ETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIET 646
Query: 948 EDERSEAENVAENFSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDEC 1007
+ S+++ +E+ S+ P+ + + E E F R + S E
Sbjct: 647 DTSSSDSDE-SESLPPSSQTPKYPESNRTPVKPSSVEEE-------DSFFRQRMFSPMEE 698
Query: 1008 EELGS--DEGEVHTPFQASVD----SFSPSDVF-DGISHEHHGRTCYSRFSRESEDNILE 1060
+EL S E + P +D + P + + + + + +RE++ E
Sbjct: 699 KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASE 758
Query: 1061 CKQNKGNSVCKNESTVLDLSSIDSSRKNKQSVSATEKKNTI------------------- 1101
NKG KNE D +R ++ TE KN+
Sbjct: 759 KVSNKGKRKHKNE---------DDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEK 809
Query: 1102 DVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQERPCHLDLHQREPNSDIPK 1161
D+L S + + +D K +GS + I Q S S ++E + +S K
Sbjct: 810 DLLPSPAGPVPSKDPKTEHGSR-KRTISQSSSLKSSSNSNKETS-----GSSKNSSSTSK 863
Query: 1162 NSSTKSLDSFRSQVLPQEGPVKESH 1186
T+ S S+ + ++ P S+
Sbjct: 864 QKKTEGKTSSSSKEVKEKAPSSSSN 888
Score = 33.9 bits (76), Expect = 1.1
Identities = 52/207 (25%), Positives = 84/207 (40%), Gaps = 47/207 (22%)
Query: 91 KGDDRRLGKKPIFSSSQQRKQ-VSDSGDIKIKSWRGNNKKECWSYLSTNKKMKSDGLGAS 149
KG+ + + +K + +Q + VS+ G K K+ N E +KK K++ ++
Sbjct: 738 KGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASE-------SKKPKTEDKNSA 790
Query: 150 GHSSSTNRNSINKTLKQDDVKEKDGTKIASKITKELKTGGKNVSGKPKTVTKSKTENGDK 209
GH S+NR S KQ KEKD L + V K KTE+G +
Sbjct: 791 GHKPSSNRES----SKQSAAKEKD----------LLPSPAGPVPSK-----DPKTEHGSR 831
Query: 210 ARLENMSPRQVVERSATAAAAATG-QKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKA 268
R +S ++ S+ + +G KN + + EG+ S + +V
Sbjct: 832 KR--TISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV----------- 878
Query: 269 KPLKKATGKDSPCLSIAGPSSRSTDSS 295
+KA S C PS+ + DSS
Sbjct: 879 --KEKAPSSSSNC----PPSAPTLDSS 899
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 56.2 bits (134), Expect = 2e-07
Identities = 137/669 (20%), Positives = 247/669 (36%), Gaps = 85/669 (12%)
Query: 197 KTVTKSK----TENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVRNQEGQISG 252
+ VTK K +EN + N R + ++SA AA G NG +Q G
Sbjct: 127 QAVTKDKFALESENISEPYFTNR--RTISQQSAEKLDAACGIDKTENGTLFEDQNVDKEG 184
Query: 253 ARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFS-----ISTECLDE 307
NV + PL T KDS +S S + +S E S +ST L E
Sbjct: 185 KALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKE 244
Query: 308 PKENGST---EEEKPSGHKLSFCDSPGQ-MMKNSVDSVKNSTVAIKSRPVSRVTNGTSN- 362
+ ++ P K+S P + + DSV N IK P+S +
Sbjct: 245 ADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQP 304
Query: 363 -KKSIHEQDTNVNNSVLKKVSGKGCSEPVPQ------AILKKRGTSNGCTAAQQRTKSTP 415
+K+ ++ +V+N + G+ PQ I KK+ + T+ T
Sbjct: 305 AEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKK-----VSLLNIATRITG 359
Query: 416 SNLTKTQGSQGESPNSVKSSVSSRQSDENVAK-----LDHNTTTEKQAPKRKMVKQVHTA 470
+ T SQ + P+ K++ S N+A L T + ++ P K +
Sbjct: 360 GGKSGTVSSQKQPPS--KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417
Query: 471 LPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKS 530
+ + +I K GE G V S+ QP+ + E S + +
Sbjct: 418 VSNIATEI----------KDGE-----------KSGTVSSQKQPALKATTDEEDSVL--N 454
Query: 531 MFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALEC 590
+ +++D ++VS QK +P + ++ D+ ++ ++ D +K ++K AL+
Sbjct: 455 IATEIKDGEKSETVSSQK--QPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKA 512
Query: 591 QNISKLD-KSLKHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYST 649
+ K ++ E + +I S K P K T D + + + D S+ S+
Sbjct: 513 TSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSS 572
Query: 650 TALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSL 709
+ + +E L + + G+ + + R ++KQ ++K D
Sbjct: 573 EQPPGLKATRDEKD-------SLLNIARGKKY-----GEKTRRVSSHKQPALKATSD--- 617
Query: 710 CNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATAD--SDVSSKCFSGQ 767
+ N N A E K + + G K A + K + ++ +++ SG
Sbjct: 618 ----KENSVPNMATETKDEQ--ISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGT 671
Query: 768 LSEKNSPKNMETSESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPR 827
+S + TS +S T + + V QR+ TG S +I
Sbjct: 672 VSSQKQLAWKATSVKKDSVSNIATE-IKDGQIRGTVSSQRQPALKATGDEKDSVSNIARE 730
Query: 828 SEDYDAGGS 836
+D + G+
Sbjct: 731 IKDGEKSGT 739
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 53.9 bits (128), Expect = 1e-06
Identities = 205/1107 (18%), Positives = 410/1107 (37%), Gaps = 175/1107 (15%)
Query: 113 SDSGDIKIKSWRGNNKKECWSYLSTNKKMKSD----GLGASGHSSSTNRNSINKTLKQDD 168
S+ D+ I S + ++ + L T +++S G G+SG +S+ + D
Sbjct: 472 SEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKD 531
Query: 169 VKEKDGTKIASKITKEL--KTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSAT 226
+ +K +K+TKEL K ++S P + DK ++ +E+
Sbjct: 532 NRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEK--- 588
Query: 227 AAAAATGQKNLLNGKGVRNQ-----EGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPC 281
GQ+N N V N+ E P+V T L + P+ + D C
Sbjct: 589 ---CGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPV--TSNSDEEC 643
Query: 282 LSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSV 341
+ + + S+ D+ + + + + P +KL P +VD
Sbjct: 644 -------NETVKEKQKLSVPVRKKDK-RNSSDSAIDNPKPNKL-----PKSKQSETVDQN 690
Query: 342 KNSTVAIK-SRPVSRVTNGTSNKKSIHEQDTNVNNSV-LKKVSGKGCSEPVPQAILKKRG 399
+S + + VSR+++ +S+ I+E TN LK +GK + K++
Sbjct: 691 SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKD-----DKGKRKRKS 745
Query: 400 TSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAP 459
+++G ++ KS S++ + Q +S +S S ++ ++++K+ TT+K+ P
Sbjct: 746 STSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEI-KSMSKIGAARTTKKRIP 804
Query: 460 KRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRP 519
N K ++ SKKG ++N+ K S+ S
Sbjct: 805 ---------------NTKDFDSSEDEKHSKKG--MDNQGHKNLK-----TSQEGSSDDAE 842
Query: 520 LKHETSTVQKSMFHDVRDNNNKD-SVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPL 578
K E T F +KD ++ E + P + Q+S D L
Sbjct: 843 RKQERET-----FSSAEGTVDKDTTIMELRDRLP-----------KKQQASASTDGVDKL 886
Query: 579 NDQEKEKLALECQNISKLDKSLKHELESK-----QICLDKSETKFPNHKETDDCDAANIC 633
+ +E+ +LE + +++ + KH L++K Q L KF ++D+ +
Sbjct: 887 SGKEQSFTSLEVRKVAETKEKSKH-LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKK 945
Query: 634 CHSVGSD------NVNSKFYSTTALKYMVSNPNENSLNSNPVCDL--------DSTSAGQ 679
G++ + K S+ E +C + T+ G+
Sbjct: 946 QSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGE 1005
Query: 680 IHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPS 739
R+ +KD + K C+ + N A +K + + G +
Sbjct: 1006 KKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS-SR 1064
Query: 740 KLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETSESPESHETPETPFVGHWNL 799
K D S+ D +K++ + +S S K ++ E E NL
Sbjct: 1065 KRQDCSSSDTEKYSMKEDGCNS-----------SDKRLKRIELRERR-----------NL 1102
Query: 800 STGVLHQRESPESDTGSATT----SSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLC 855
S+ +R + E +GS+++ SS+D K + + + R + T
Sbjct: 1103 SS----KRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1158
Query: 856 H-DFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQ-----VNSTSDDEIPRKRP 909
D SSSD ++ I + + E K+K + N + S+ D+ + + P
Sbjct: 1159 QADITSSSSSDIEDDDQNSIGEGS-SDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1217
Query: 910 EIWSRSAIVHSRERENIPRGSVQFAQEIDQVSS--SADE---TEDERSEAENVAENFSIS 964
V + +N P + ++++ + S+DE ++DE E + +
Sbjct: 1218 ------VTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEE 1271
Query: 965 NPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTPFQ-- 1022
NP ++ + +N + +E + + + + +S E E + + H +
Sbjct: 1272 NPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR 1331
Query: 1023 -----ASVDS----FSPSDVFDGISHEHHGRTCYSRFSR--ESEDNILECKQNK------ 1065
+S DS F S V + +S + +R ++ E E+N KQ K
Sbjct: 1332 NRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIK 1391
Query: 1066 --GNSVCKNESTVLDLSSIDSSRKNKQSVSATEKKNTIDVLSS------RSRQLLREDKK 1117
+S +N+S + + ++ E+++ D S + R++L++DK
Sbjct: 1392 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL 1451
Query: 1118 VNNGSNVENDIQQRSKFLDSDVKSQER 1144
N + ++R K + + +E+
Sbjct: 1452 RTETQNALKEEEERRKRIAEREREREK 1478
Score = 36.6 bits (83), Expect = 0.17
Identities = 111/596 (18%), Positives = 224/596 (37%), Gaps = 86/596 (14%)
Query: 82 QKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDSGDIKIKSWRGNNKKECWSYLS--TNK 139
+K QA+A G D+ GK+ F+S + RK V+++ + K K + K+ LS K
Sbjct: 872 KKQQASASTDGVDKLSGKEQSFTSLEVRK-VAETKE-KSKHLKTKTCKKVQDGLSDIAEK 929
Query: 140 KMKSDGLG-ASGHSSSTNRNSINKTLKQDDVKEK------------DGTKIA-------- 178
+K D S ++ + K D K+K DGT+
Sbjct: 930 FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 989
Query: 179 -SKITKELKTGGKNVSGKPKTV----TKSKTENGDKARLE----NMSPRQVVERSATAAA 229
K K++K G + K K + +K K E D A + ++S A
Sbjct: 990 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAY 1049
Query: 230 AATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSS 289
++ L GK R ++ S K + K LK+ ++ LS S
Sbjct: 1050 GREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLS----SK 1105
Query: 290 RSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQ------MMKNSVDSVKN 343
R+T S S++ + ++N ++ S K + + D +
Sbjct: 1106 RNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1165
Query: 344 STVAIKSRPVSRVTNGTSNKKSIHEQDTNV----NNSVLKKVSGKGCSEPVPQAILKKRG 399
S+ I+ + + G+S+++ I N+ + + + S+ VP +
Sbjct: 1166 SSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDD 1225
Query: 400 TSN--GCTAAQQRTKSTPSNLTKTQ-GSQGESPNSVKSSVSSRQSDEN----VAKLDHNT 452
++ A + + +NL+ + GS + P K + +Q++EN AK N+
Sbjct: 1226 DNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKR-TGKQNEENPGDEEAKNQVNS 1284
Query: 453 TTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKT 512
++ + + K P+ +++ ++ + GE K + K G+
Sbjct: 1285 ESDSDSEESKK--------PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR----- 1331
Query: 513 QPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRP 572
++R + E S D +++ + VSE + + +++ ++ E Q S +
Sbjct: 1332 ---NRRKVSSEDSEDS-----DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK- 1382
Query: 573 DPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCD 628
Q+K++ ++ Q S + E E ++ ++ E + +E D+ D
Sbjct: 1383 --------QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 53.9 bits (128), Expect = 1e-06
Identities = 205/1107 (18%), Positives = 410/1107 (37%), Gaps = 175/1107 (15%)
Query: 113 SDSGDIKIKSWRGNNKKECWSYLSTNKKMKSD----GLGASGHSSSTNRNSINKTLKQDD 168
S+ D+ I S + ++ + L T +++S G G+SG +S+ + D
Sbjct: 510 SEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKD 569
Query: 169 VKEKDGTKIASKITKEL--KTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSAT 226
+ +K +K+TKEL K ++S P + DK ++ +E+
Sbjct: 570 NRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEK--- 626
Query: 227 AAAAATGQKNLLNGKGVRNQ-----EGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPC 281
GQ+N N V N+ E P+V T L + P+ + D C
Sbjct: 627 ---CGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPV--TSNSDEEC 681
Query: 282 LSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSV 341
+ + + S+ D+ + + + + P +KL P +VD
Sbjct: 682 -------NETVKEKQKLSVPVRKKDK-RNSSDSAIDNPKPNKL-----PKSKQSETVDQN 728
Query: 342 KNSTVAIK-SRPVSRVTNGTSNKKSIHEQDTNVNNSV-LKKVSGKGCSEPVPQAILKKRG 399
+S + + VSR+++ +S+ I+E TN LK +GK + K++
Sbjct: 729 SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKD-----DKGKRKRKS 783
Query: 400 TSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAP 459
+++G ++ KS S++ + Q +S +S S ++ ++++K+ TT+K+ P
Sbjct: 784 STSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEI-KSMSKIGAARTTKKRIP 842
Query: 460 KRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRP 519
N K ++ SKKG ++N+ K S+ S
Sbjct: 843 ---------------NTKDFDSSEDEKHSKKG--MDNQGHKNLK-----TSQEGSSDDAE 880
Query: 520 LKHETSTVQKSMFHDVRDNNNKD-SVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPL 578
K E T F +KD ++ E + P + Q+S D L
Sbjct: 881 RKQERET-----FSSAEGTVDKDTTIMELRDRLP-----------KKQQASASTDGVDKL 924
Query: 579 NDQEKEKLALECQNISKLDKSLKHELESK-----QICLDKSETKFPNHKETDDCDAANIC 633
+ +E+ +LE + +++ + KH L++K Q L KF ++D+ +
Sbjct: 925 SGKEQSFTSLEVRKVAETKEKSKH-LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKK 983
Query: 634 CHSVGSD------NVNSKFYSTTALKYMVSNPNENSLNSNPVCDL--------DSTSAGQ 679
G++ + K S+ E +C + T+ G+
Sbjct: 984 QSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGE 1043
Query: 680 IHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPS 739
R+ +KD + K C+ + N A +K + + G +
Sbjct: 1044 KKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS-SR 1102
Query: 740 KLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETSESPESHETPETPFVGHWNL 799
K D S+ D +K++ + +S S K ++ E E NL
Sbjct: 1103 KRQDCSSSDTEKYSMKEDGCNS-----------SDKRLKRIELRERR-----------NL 1140
Query: 800 STGVLHQRESPESDTGSATT----SSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLC 855
S+ +R + E +GS+++ SS+D K + + + R + T
Sbjct: 1141 SS----KRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1196
Query: 856 H-DFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQ-----VNSTSDDEIPRKRP 909
D SSSD ++ I + + E K+K + N + S+ D+ + + P
Sbjct: 1197 QADITSSSSSDIEDDDQNSIGEGS-SDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1255
Query: 910 EIWSRSAIVHSRERENIPRGSVQFAQEIDQVSS--SADE---TEDERSEAENVAENFSIS 964
V + +N P + ++++ + S+DE ++DE E + +
Sbjct: 1256 ------VTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEE 1309
Query: 965 NPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTPFQ-- 1022
NP ++ + +N + +E + + + + +S E E + + H +
Sbjct: 1310 NPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR 1369
Query: 1023 -----ASVDS----FSPSDVFDGISHEHHGRTCYSRFSR--ESEDNILECKQNK------ 1065
+S DS F S V + +S + +R ++ E E+N KQ K
Sbjct: 1370 NRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIK 1429
Query: 1066 --GNSVCKNESTVLDLSSIDSSRKNKQSVSATEKKNTIDVLSS------RSRQLLREDKK 1117
+S +N+S + + ++ E+++ D S + R++L++DK
Sbjct: 1430 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL 1489
Query: 1118 VNNGSNVENDIQQRSKFLDSDVKSQER 1144
N + ++R K + + +E+
Sbjct: 1490 RTETQNALKEEEERRKRIAEREREREK 1516
Score = 36.6 bits (83), Expect = 0.17
Identities = 111/596 (18%), Positives = 224/596 (37%), Gaps = 86/596 (14%)
Query: 82 QKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDSGDIKIKSWRGNNKKECWSYLS--TNK 139
+K QA+A G D+ GK+ F+S + RK V+++ + K K + K+ LS K
Sbjct: 910 KKQQASASTDGVDKLSGKEQSFTSLEVRK-VAETKE-KSKHLKTKTCKKVQDGLSDIAEK 967
Query: 140 KMKSDGLG-ASGHSSSTNRNSINKTLKQDDVKEK------------DGTKIA-------- 178
+K D S ++ + K D K+K DGT+
Sbjct: 968 FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 1027
Query: 179 -SKITKELKTGGKNVSGKPKTV----TKSKTENGDKARLE----NMSPRQVVERSATAAA 229
K K++K G + K K + +K K E D A + ++S A
Sbjct: 1028 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAY 1087
Query: 230 AATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSS 289
++ L GK R ++ S K + K LK+ ++ LS S
Sbjct: 1088 GREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLS----SK 1143
Query: 290 RSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQ------MMKNSVDSVKN 343
R+T S S++ + ++N ++ S K + + D +
Sbjct: 1144 RNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1203
Query: 344 STVAIKSRPVSRVTNGTSNKKSIHEQDTNV----NNSVLKKVSGKGCSEPVPQAILKKRG 399
S+ I+ + + G+S+++ I N+ + + + S+ VP +
Sbjct: 1204 SSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDD 1263
Query: 400 TSN--GCTAAQQRTKSTPSNLTKTQ-GSQGESPNSVKSSVSSRQSDEN----VAKLDHNT 452
++ A + + +NL+ + GS + P K + +Q++EN AK N+
Sbjct: 1264 DNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKR-TGKQNEENPGDEEAKNQVNS 1322
Query: 453 TTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKT 512
++ + + K P+ +++ ++ + GE K + K G+
Sbjct: 1323 ESDSDSEESKK--------PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR----- 1369
Query: 513 QPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRP 572
++R + E S D +++ + VSE + + +++ ++ E Q S +
Sbjct: 1370 ---NRRKVSSEDSEDS-----DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK- 1420
Query: 573 DPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCD 628
Q+K++ ++ Q S + E E ++ ++ E + +E D+ D
Sbjct: 1421 --------QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1468
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/92 (41%), Positives = 53/92 (57%), Gaps = 22/92 (23%)
Query: 1285 SLAQYLINQTLLLAR------------DSSKPQGIT-------HIDTLNRWSELTSPLDS 1325
S+ Q+L+++TLLLA ++ G+T L RW+EL SPLD
Sbjct: 764 SVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDE 823
Query: 1326 S-ASIT-MASFSSED-CSPQGEWTILELETQH 1354
S ASIT + SFS +D SPQG+WT++E+ET H
Sbjct: 824 SRASITSVTSFSPDDVASPQGDWTVVEVETFH 855
Score = 32.7 bits (73), Expect = 2.4
Identities = 17/30 (56%), Positives = 19/30 (63%)
Query: 848 SKCGTMLCHDFLGRSSSDTSTPEELKIYDS 877
S T+ D G SSS TSTPEEL+ YDS
Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDS 647
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/92 (41%), Positives = 53/92 (57%), Gaps = 22/92 (23%)
Query: 1285 SLAQYLINQTLLLAR------------DSSKPQGIT-------HIDTLNRWSELTSPLDS 1325
S+ Q+L+++TLLLA ++ G+T L RW+EL SPLD
Sbjct: 1033 SVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDE 1092
Query: 1326 S-ASIT-MASFSSED-CSPQGEWTILELETQH 1354
S ASIT + SFS +D SPQG+WT++E+ET H
Sbjct: 1093 SRASITSVTSFSPDDVASPQGDWTVVEVETFH 1124
Score = 32.7 bits (73), Expect = 2.4
Identities = 17/30 (56%), Positives = 19/30 (63%)
Query: 848 SKCGTMLCHDFLGRSSSDTSTPEELKIYDS 877
S T+ D G SSS TSTPEEL+ YDS
Sbjct: 887 SPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/92 (41%), Positives = 53/92 (57%), Gaps = 22/92 (23%)
Query: 1285 SLAQYLINQTLLLAR------------DSSKPQGIT-------HIDTLNRWSELTSPLDS 1325
S+ Q+L+++TLLLA ++ G+T L RW+EL SPLD
Sbjct: 725 SVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDE 784
Query: 1326 S-ASIT-MASFSSED-CSPQGEWTILELETQH 1354
S ASIT + SFS +D SPQG+WT++E+ET H
Sbjct: 785 SRASITSVTSFSPDDVASPQGDWTVVEVETFH 816
Score = 32.7 bits (73), Expect = 2.4
Identities = 17/30 (56%), Positives = 19/30 (63%)
Query: 848 SKCGTMLCHDFLGRSSSDTSTPEELKIYDS 877
S T+ D G SSS TSTPEEL+ YDS
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDS 608
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 52.4 bits (124), Expect = 3e-06
Identities = 112/558 (20%), Positives = 208/558 (37%), Gaps = 80/558 (14%)
Query: 139 KKMKSDG-LGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASKITKELKTGGKNVSGKPK 197
+K++++G + +++ +S + + ++++V+ K A + GK + +
Sbjct: 66 RKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASE 125
Query: 198 TVTKSKTENGDKARLENMSPRQ--VVERSATAAAAATGQKNLLNGKGVRNQEGQISGARP 255
+ + ++ + D + P Q V ++ A A K+ + +++ +P
Sbjct: 126 SSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKP 185
Query: 256 KVLTGNLNVQAKAKPL------KKATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPK 309
K+ + Q KA P K A GK + S + SS S DS E + +T PK
Sbjct: 186 KITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 310 EN---------GSTEEEKPSGHKLSFCDSPGQM---MKNSVDSVKNSTVAIKSRPVSRVT 357
+ +T K S + S D + MKN S+V S P + +
Sbjct: 246 KQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPY--SSVPPPSAPPPKKS 303
Query: 358 NGTSNKKSIHEQDTNVNNS-----------------VLKKVSGKGCSEPVP--QAILKKR 398
GT K E+ V +S K V K ++P P +A
Sbjct: 304 LGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSS 363
Query: 399 GTSNGCTAAQQRTKSTPSNLTKTQGSQ----GESPNSVKSSVSSRQSDENVAKL-----D 449
+S+ ++ S P+ TK ++ +SP +VK + + +Q KL D
Sbjct: 364 DSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSP-AVKPAAAPKQPVGGGQKLLTRKAD 422
Query: 450 HNTTTEK--QAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQ------ 501
+++ E+ + + K K V T PK AK A+ Q+ +G ++ DS
Sbjct: 423 SSSSEEESSSSEEEKTKKMVATTKPKATAK-AALSLPAKQAPQGSRDSSSDSDSSSSEEE 481
Query: 502 ---------KMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKP 552
K P +V PS K + S D ++ + + +P
Sbjct: 482 EEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRP 541
Query: 553 LINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHEL-------E 605
A+ S A + ++ ++EK+K A+ L K ++E +
Sbjct: 542 QAPKANGTSALTAQNGKAAKNSEE--EEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQ 599
Query: 606 SKQICLDKSETKFPNHKE 623
+K+I L T FP K+
Sbjct: 600 AKKIKLQTPNT-FPKRKK 616
Score = 50.8 bits (120), Expect = 9e-06
Identities = 94/454 (20%), Positives = 179/454 (39%), Gaps = 62/454 (13%)
Query: 363 KKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQ--QRTKSTPSNLTK 420
KK D+ ++ ++V G + A K+ G G AA+ + + S S+
Sbjct: 79 KKKASSSDSEDSSEEEEEVQGPPAKKAAVPA--KRVGLPPGKAAAKASESSSSEESSDDD 136
Query: 421 TQGSQGESP--NSVKSSVSSRQSDENVAKL---DHNTTTEKQAPKRKMVK------QVHT 469
+ Q + P VK + ++ AK D ++++E + PK + K + T
Sbjct: 137 DEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQT 196
Query: 470 ALPKVNAKIVAMPKNLN---------QSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPL 520
P A+ A PK N S + ++++ K P + + K Q ++ P+
Sbjct: 197 KAPPKPAR--AAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPV 254
Query: 521 KHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLND 580
K T+ +KS ++++ D EQK KP+ N S ++ P P+K L
Sbjct: 255 KAATTPTRKS---SSSEDSSSDEEEEQK--KPMKNKPGPYS---SVPPPSAPPPKKSLGT 306
Query: 581 QEKEKLALECQNI-SKLDKSLKHELESKQ-------ICLDKSETKFPNHKETDDCDAANI 632
Q +K + Q + S D S + + S++ + K+ TK P K+ + + +
Sbjct: 307 QPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSS 366
Query: 633 CCHSVGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVG- 691
S D SK TT +NS N V +T + + + + VG
Sbjct: 367 DSDSSEDDEAPSKPAGTT----------KNSSNKPAV----TTKSPAVKPAAAPKQPVGG 412
Query: 692 --RKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDE 749
+ T K S E+ S E+T + + + +K L++P+K + + + D
Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKA---ALSLPAKQAPQGSRDS 469
Query: 750 DKHATADSDVSSKCFSGQLSEKNSPKNMETSESP 783
+ + S + + + + K P+ + +P
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAP 503
Score = 34.7 bits (78), Expect = 0.64
Identities = 90/482 (18%), Positives = 165/482 (34%), Gaps = 71/482 (14%)
Query: 726 KKSKVPVEGLTIP----------SKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPK 775
KK+ VP + + +P S S+ES+ D+D+ V + K PK
Sbjct: 103 KKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPK 162
Query: 776 NMETSES----------PESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIK 825
++S+S P++ + TP R +P+ G A +SS
Sbjct: 163 KAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSS 222
Query: 826 PRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRS---SSDTSTPEELKIYDSNLRIE 882
S S DD + T+ + ++ ++ T T + DS+ E
Sbjct: 223 SSS-------SSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEE 275
Query: 883 VKMKKQSNNDLFQVNSTSDDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSS 942
+ KK N +S P + + ++ P+ +V+ Q ++
Sbjct: 276 EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQP-----------PKKAVEKQQPVESSED 324
Query: 943 SADETEDERSEAENVAENFSISN------PAPQQFQGIINLAFEDATENECREFSATKKF 996
S+DE++ E + +S PA + + + + D++E++
Sbjct: 325 SSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTT 384
Query: 997 KRSVLLSVDECEELGSDEGEVHTPFQASVDSFSPSDVFDGISHEHHGRTCYSRFSRESED 1056
K S S++ V T A + +P G + R S S E
Sbjct: 385 KNS------------SNKPAVTTKSPAVKPAAAPKQPVGG-GQKLLTRKADSSSSEEESS 431
Query: 1057 NILECKQNKGNSVCKNESTVLDLSSI----------DSSRKNKQSVSATEKKNTIDVLSS 1106
+ E K K + K ++T S+ DSS + S S E++ T
Sbjct: 432 SSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK 491
Query: 1107 RSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQERPCHLDLHQREPNSDIPKNSSTK 1166
+ Q + + ++ + + S SD S+E L + P PK + T
Sbjct: 492 KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK-GKGSPRPQAPKANGTS 550
Query: 1167 SL 1168
+L
Sbjct: 551 AL 552
>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
Length = 2472
Score = 51.6 bits (122), Expect = 5e-06
Identities = 234/1196 (19%), Positives = 432/1196 (36%), Gaps = 187/1196 (15%)
Query: 196 PKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVRNQE-GQISGAR 254
P K K ++ E M V+ + T G L + N E G +
Sbjct: 1106 PTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDC---GMAEHLEKSSLSNNECGSLDKTS 1162
Query: 255 PKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEP---KEN 311
P++ N + + KA + T + C S S + SS+ + P ++
Sbjct: 1163 PEMSNSNNDERKKALISSRKTSTE--CASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQT 1220
Query: 312 GSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSR--PVSRVTNGTSNK----KS 365
T E+ F SP + ++V N IK+ P ++ GT +K K
Sbjct: 1221 FITLEKFDGSENRPFSPSPLNNISSTVTVKNNQETMIKTDFLPKAKQREGTFSKSDSEKI 1280
Query: 366 IHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQ 425
++ + + + +G S+P+ ++ +K T + P L +T+
Sbjct: 1281 VNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKN-TEESVEGIVVLENNPPGLLNQTECV- 1338
Query: 426 GESPNSVKSSVSSRQSD---------ENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNA 476
S N V S S+ + D EN L+ NT EK K+ P V
Sbjct: 1339 --SDNQVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKE---NTPPV-- 1391
Query: 477 KIVAMPKNLNQSKKGETLNNKDSKQKMPP--GQVISKTQPSSQRPLKH--------ETST 526
+++ + +N+ + + N+ + ++ +V+ T S + H E
Sbjct: 1392 -VISADQMVNEDSQVQITPNQKTLRRSSRRRSEVVESTTESQDKENSHQKKERRKEEEKP 1450
Query: 527 VQKSMFHDVRDNNNKDS-VSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEK 585
+QKS H D K ++EQ + LI S + + ++S + +
Sbjct: 1451 LQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETE---------- 1500
Query: 586 LALECQNISKLD-KSLKHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNS 644
QN K D +++K E + Q +DKS K + A+ + S NS
Sbjct: 1501 -----QNKKKADPENIKSEGDGTQDIVDKSSEKLVRGRTRYQTRRAS---QGLLSSIENS 1552
Query: 645 KFYSTTALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDT----NKQSS 700
+ S+ A + + +D I D+E +V +++ N+
Sbjct: 1553 ESDSSEAKEEGSRKKRSGKWKNKSNESVD---------IQDQEEKVVKQECIKAENQSHD 1603
Query: 701 IKCV--EDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATAD-- 756
K EDVS+ +P ++ + S V + L +P L + + E+K+ T+
Sbjct: 1604 YKATSEEDVSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPN---VCEEKNETSKYA 1660
Query: 757 --SDVSSKCFSGQLSEKNSPKNMETSESPESHETPETPFVGHWNLST---------GVLH 805
S S L +N+ K + +S ++ E+ +G ++S+ H
Sbjct: 1661 EYSFTSLPVPESNLRTRNAIKRLHKRDSFDNCSLGESSKIGISDISSLSEKTFQTLECQH 1720
Query: 806 QRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSD 865
+R + + +P+ + + ++ ND IS+ + S +
Sbjct: 1721 KRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTEN---NDVEISETKKADVQAPVSPSETS 1777
Query: 866 TSTP-EELKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDEIPRKRPEIWSRSAIVHSRERE 924
+ P E + D + + + + +ND T +D + I S + + +E
Sbjct: 1778 QANPYSEGQFLDEHHSVNFHLGLKEDND------TINDSL------IVSETKSKENTMQE 1825
Query: 925 NIPRGSVQFAQEI-DQVSSSADETEDERSEAENVAENFSISNPAPQQFQGIINLAFEDAT 983
++P G V F +EI D SS A E + E+ ENF P +
Sbjct: 1826 SLPSGIVNFREEICDMDSSEAMSLESQ----ESPNENFKTVGPCLGD------------S 1869
Query: 984 ENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTPFQASVDSFSPSDVFDGISHEHHG 1043
+N +E TK+ K ++ E + EG +++++ ++ G HG
Sbjct: 1870 KNVSQESLETKEEKPEETPKMELSLENVTVEGNACKVTESNLEKAKTMELNVGNEASFHG 1929
Query: 1044 RTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLSSIDSSRKNKQSVSATEKKNTIDV 1103
+ ++ E I E K+N D S D+++ N + V ATE+ N+
Sbjct: 1930 QE-RTKTGISEEAAIEENKRN-------------DDSEADTAKLNAKEV-ATEEFNSDIS 1974
Query: 1104 LSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQERPCHLDLHQREPNSDIPKNS 1163
LS + + K+N + + +DV DLH E + KN+
Sbjct: 1975 LSDNTTPV-----KLNAQTEISEQTAAGELDGGNDVS--------DLHSSEETNTKMKNN 2021
Query: 1164 STKSLDSFRSQVLPQEGPVKESHSTTTEKANIALSAGDIDDCDTLAQTRMYDHRPSKTLS 1223
+++ E + H TE I D+ +T T D+ T+
Sbjct: 2022 ---------EEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTAEMDNFVCDTVE 2072
Query: 1224 PIYEMDVIEA-----------FEQKVESETHVTDMDFEDDQHFAKQDWTLLKQLLSEQDS 1272
E +I+A E+K+++ V + D + H Q Q L+ S
Sbjct: 2073 MSTEEGIIDANKTETNTEYSKSEEKLDNNQMVMESDILQEDHHTSQKVEEPSQCLA---S 2129
Query: 1273 NLDVTNSVPEDLSLAQYLINQ---TLLLARDSSKPQGITHIDTLNRWSELTSPLDS 1325
++ + ED + + + + +L+ A DS P G + T WS L SP S
Sbjct: 2130 GTAISELIIEDNNASPQKLRELDPSLVSANDS--PSG---MQTRCVWSPLASPSTS 2180
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 49.7 bits (117), Expect = 2e-05
Identities = 145/783 (18%), Positives = 270/783 (34%), Gaps = 103/783 (13%)
Query: 126 NNKKECWSYLSTNKKMKSDGLGASGHSSSTNRNSINKTLKQ---------DDVKEKDGTK 176
N + S L T + + A + ++N + + K+ KE+
Sbjct: 196 NVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSED 255
Query: 177 IASKITKELKTGGKNVSGKPKTVT-----------KSKTENGDKARLENMSPRQVVERSA 225
+A K +GG+ + PK+ K+ T+ + L N +Q
Sbjct: 256 MADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQK 315
Query: 226 TAAAAATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIA 285
+ +K N KG R +E + + + K K K+A K+ L +
Sbjct: 316 NKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLP 375
Query: 286 GPSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNST 345
+ + ++E + L + +G T+ S H + + + +
Sbjct: 376 SEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSD--------LSSFEEDTEEEV 427
Query: 346 VAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKV-SGKGCSEPVPQAILKKRGTSNGC 404
V S +T+ K ++ T ++S K S + P K S+
Sbjct: 428 VTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDE 487
Query: 405 TAAQQRTKSTPS-----------NLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTT 453
+QR +S N K + + + KSS + Q +V ++
Sbjct: 488 LTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDL--EESS 545
Query: 454 TEKQAPKRKMVKQVHTALPKVNAKIVAMPK-------NLNQSKKGETLNNKDSKQKMPPG 506
T+ PK +K+V KV K VA+ K N+ ++ K + +DSK+ +
Sbjct: 546 TKSLEPKAARIKEVLKER-KVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTS 604
Query: 507 QVISKTQPSSQRPLKHETSTVQKS--------MFHDVRDNNNKDSVSEQKPHKP----LI 554
+ K + SS + LKH + + S H V +N N+ + + + ++
Sbjct: 605 EHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIM 664
Query: 555 NLASEISDAEALQSS------CRPDPQKPLNDQEKEK-LALECQNISKLDKSLKHELESK 607
E +D ++ C +PQK + + EK L + L LK E++S
Sbjct: 665 EGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSS 724
Query: 608 QICLDKSETKFPN-----HKETDDC-----DAANICCHSVG---SDNV-----NSKFYST 649
+ ++ +T + HK DC D + G +N+ +K S
Sbjct: 725 KEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSD 784
Query: 650 TALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSL 709
+ + NE L+ V D + ++I EN RK+ NK+ E
Sbjct: 785 DKTERKSKHRNERKLS---VLGKDGKPVSE-YIIKTDENV--RKENNKKERRLSAEKTKA 838
Query: 710 CNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLS 769
+ R + ++ SK G+T+ + + EDK +++ S ++
Sbjct: 839 EHKSRRSSDSKIQKDSLGSK--QHGITLQRR---SESYSEDKCDMDSTNMDSNLKPEEVV 893
Query: 770 EKNSPKNMETSE-----SPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDI 824
K + E +S + V L G Q +P+ D T +D
Sbjct: 894 HKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSE 953
Query: 825 KPR 827
K R
Sbjct: 954 KQR 956
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 48.9 bits (115), Expect = 3e-05
Identities = 91/437 (20%), Positives = 155/437 (35%), Gaps = 41/437 (9%)
Query: 195 KPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVRNQEGQISGAR 254
+P T K E+ + + + R + ++SA AA G NG +Q G
Sbjct: 127 QPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKA 186
Query: 255 PKVLTGNLNVQAKAKPLKKATGKDSPCLS---IAGPSS--RSTDSSMEFSISTECLDEPK 309
NV + PL T KD +S + G S S +SS +ST L E
Sbjct: 187 LPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD 246
Query: 310 ENGST---EEEKPSGHKLSFCDSPGQMM-KNSVDSVKNSTVAIKSRPVSRVTNGTSN--K 363
+ ++ P K+S P + + DSV N IK P+S + +
Sbjct: 247 PSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAE 306
Query: 364 KSIHEQDTNVNN--SVLKKVSGKGCSEPVPQA----ILKKR-----------GTSNGCTA 406
K+ ++ +V+N + +KK G P Q+ I KK+ G T
Sbjct: 307 KATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTV 366
Query: 407 AQQRTKSTPSNLTKTQ-----------GSQGESPNSVKSSVSSRQSDENVAKLDHNTTTE 455
+ Q+ ++ + KT G Q + +S K +DE + + T +
Sbjct: 367 SSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIK 426
Query: 456 KQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPS 515
+ Q AL + ++ + K GE S++ PP + +
Sbjct: 427 DGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK--PPALTATSDEEG 484
Query: 516 SQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQ 575
S + E +KS R + S++K I + + SS +P
Sbjct: 485 SVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
Query: 576 KPLNDQEKEKLALECQN 592
K +D+E L + +N
Sbjct: 545 KGTSDEEDSVLGIAREN 561
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 48.1 bits (113), Expect = 6e-05
Identities = 91/437 (20%), Positives = 155/437 (35%), Gaps = 41/437 (9%)
Query: 195 KPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVRNQEGQISGAR 254
+P T K E+ + + + R + ++SA AA G NG +Q G
Sbjct: 127 QPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKA 186
Query: 255 PKVLTGNLNVQAKAKPLKKATGKDSPCLS---IAGPSS--RSTDSSMEFSISTECLDEPK 309
NV + PL T KD +S + G S S +SS +ST L E
Sbjct: 187 LPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD 246
Query: 310 ENGST---EEEKPSGHKLSFCDSPGQMM-KNSVDSVKNSTVAIKSRPVSRVTNGTSN--K 363
+ ++ P K+S P + + DSV N IK P+S + +
Sbjct: 247 PSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAE 306
Query: 364 KSIHEQDTNVNN--SVLKKVSGKGCSEPVPQA----ILKKR-----------GTSNGCTA 406
K+ ++ +V+N + +KK G P Q+ I KK+ G T
Sbjct: 307 KATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTV 366
Query: 407 AQQRTKSTPSNLTKTQ-----------GSQGESPNSVKSSVSSRQSDENVAKLDHNTTTE 455
+ Q+ ++ + KT G Q + +S K +DE + + T +
Sbjct: 367 SSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIK 426
Query: 456 KQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPS 515
+ Q AL + ++ + K GE S++ PP + +
Sbjct: 427 DGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK--PPALTATSDEEG 484
Query: 516 SQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQ 575
S + E +KS R + S++K I + + SS +P
Sbjct: 485 SVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
Query: 576 KPLNDQEKEKLALECQN 592
K +D+E L + +N
Sbjct: 545 KGTSDEEDSVLGIAREN 561
Score = 43.9 bits (102), Expect = 0.001
Identities = 96/462 (20%), Positives = 181/462 (39%), Gaps = 77/462 (16%)
Query: 181 ITKELKTGGKN--VSGKPKTVTKSKTENGDKAR------LENMSPRQVVERSATAAAAAT 232
I + GGK+ VS + + +K+ ++ D A + + V + A A T
Sbjct: 353 IATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
Query: 233 GQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRST 292
+++ ++ ++G+ SG V ++ +P KAT + +S
Sbjct: 413 DEEDSVSNIATEIKDGEKSGT----------VSSQKQPALKATTDEKDSVS--------- 453
Query: 293 DSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMM---KNSVDSVKNSTVAIK 349
+I+TE D K +G+ +KP + D G ++ + + D K+ TV+ +
Sbjct: 454 ------NIATEIKDGEK-SGTVSSQKPPALTAT-SDEEGSVLSIARENKDGEKSRTVSSR 505
Query: 350 SRPVSRVTNGTSNKKSIHEQDTNVNNSVLKK---VSGKGCSEPVPQAILKKRGTSNGCTA 406
+P + T+ E+D+ N + KK +S K S+ P +GTS+ +
Sbjct: 506 KKPALKATSD--------EKDSFSNITRGKKDGEISRKVSSQKPPTL----KGTSDEEDS 553
Query: 407 AQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQ 466
+ K++ E P +K+S + + S N+A+ + K+ RK
Sbjct: 554 VLGIARENKDG-EKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSL 612
Query: 467 VHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETST 526
T+ K + N+ + KK ++ K S QK PP + + S + E
Sbjct: 613 EATSDEKDSF------SNITREKKDGEISRKVSSQK-PPALKGTSDEEDSVLGIAREN-- 663
Query: 527 VQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKL 586
+D +VS +KP P + S+ D+ + + D +K ++
Sbjct: 664 ---------KDGEKSRTVSSEKP--PGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQP 712
Query: 587 ALE--CQNISKLDKSLKHELESKQICLDKSETKFPNHKETDD 626
AL+ C + ++ E + +QI S K P K T D
Sbjct: 713 ALKAICDKEDSV-PNMATEKKDEQISGTVSCQKQPALKATSD 753
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 47.0 bits (110), Expect = 1e-04
Identities = 66/323 (20%), Positives = 125/323 (38%), Gaps = 24/323 (7%)
Query: 301 STECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGT 360
+T L+ KE+ +E++ G S S G NS S +STV+ S S ++ T
Sbjct: 489 TTSVLEPKKEH---KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 361 SNKKSIHEQDTNVNNSVLKKVSGKGC------------SEPVPQAILKKRGTSNGCTAAQ 408
S++ S ++ + S + + S I +R ++ +
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 409 QRTKSTPSNLTKTQGSQGESPNSVKSSVSS----RQSDENVAKLDHNTTTEKQAPKRKMV 464
+R +PS + S+ + ++S S R+ D+ L N+ K K +
Sbjct: 606 RRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 465 KQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHET 524
K+ + + K + Q K+ E ++ K K + S+R
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 525 STVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKE 584
S K + HD R ++ K + + K H + +S S +E+ SS +KP + + +
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSG--SDSSGRSSSESPGSSKEKKAKKPKHSRSR- 782
Query: 585 KLALECQNISKLDKSLKHELESK 607
++E S S KH+ +S+
Sbjct: 783 --SVEKSQRSGKKASRKHKSKSR 803
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 47.0 bits (110), Expect = 1e-04
Identities = 66/323 (20%), Positives = 125/323 (38%), Gaps = 24/323 (7%)
Query: 301 STECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGT 360
+T L+ KE+ +E++ G S S G NS S +STV+ S S ++ T
Sbjct: 489 TTSVLEPKKEH---KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 361 SNKKSIHEQDTNVNNSVLKKVSGKGC------------SEPVPQAILKKRGTSNGCTAAQ 408
S++ S ++ + S + + S I +R ++ +
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 409 QRTKSTPSNLTKTQGSQGESPNSVKSSVSS----RQSDENVAKLDHNTTTEKQAPKRKMV 464
+R +PS + S+ + ++S S R+ D+ L N+ K K +
Sbjct: 606 RRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 465 KQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHET 524
K+ + + K + Q K+ E ++ K K + S+R
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 525 STVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKE 584
S K + HD R ++ K + + K H + +S S +E+ SS +KP + + +
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSG--SDSSGRSSSESPGSSKEKKAKKPKHSRSR- 782
Query: 585 KLALECQNISKLDKSLKHELESK 607
++E S S KH+ +S+
Sbjct: 783 --SVEKSQRSGKKASRKHKSKSR 803
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 45.8 bits (107), Expect = 3e-04
Identities = 125/651 (19%), Positives = 233/651 (35%), Gaps = 129/651 (19%)
Query: 484 NLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDS 543
++ + + ET + +D +P G + T + PL S + H +D+ DS
Sbjct: 44 SVERHSENETSDREDG---LPKGHHV--TDSENDEPLNLNASDSESEELHRQKDS---DS 95
Query: 544 VSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHE 603
SE++ P + +E + S + P +D E E+L + S+ + KH
Sbjct: 96 ESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHP 155
Query: 604 LESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPNENS 663
+I ++ + + ET+D ALK +S
Sbjct: 156 ASDSEI--EELQKSPASDSETED------------------------ALKPQIS------ 183
Query: 664 LNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQ 723
D +S + H SD EN+ K S + + + + E + A
Sbjct: 184 -------DSESEEPPR-HQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQAS 235
Query: 724 EDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNS--PKNMETSE 781
+ + ++P ++SD + D +H +DS+ + + ++S+ S P + S+
Sbjct: 236 DSENEELP------KPRISDSESEDPPRHQASDSE-NEELPKPRISDSESEDPPRNQASD 288
Query: 782 SPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDG 841
S E+ E P+ P V + S G ++ P SD+ + S KP S+D
Sbjct: 289 S-ENEELPK-PRVSD-SESEG---PQKGPASDSETEDASRHKQKPESDD----------- 331
Query: 842 SNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTSD 901
+DR T + +D S S + K + S+ E K++ ++D +
Sbjct: 332 DSDRENKGEDTEMQND----SFHSDSHMDRKKFHSSDSEEEEHKKQKMDSD--------E 379
Query: 902 DEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAENVAENF 961
DE + ++ R A V S + + + D S +D D+ + E +
Sbjct: 380 DEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIAS- 438
Query: 962 SISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTPF 1021
D+ E +E S K +E + GSD +
Sbjct: 439 -------------------DSEEEAGKELSDKKN---------EEKDLFGSDSESGNEEE 470
Query: 1022 QASVDSFSPSDVFDGISHEHHGRTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLSS 1081
D F S D E G + E + E + + + K + LS
Sbjct: 471 NLIADIFGESG--DEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSD 528
Query: 1082 IDSSRKNKQSVSATEKKN---------TIDVLSS---RSRQLLREDKKVNN 1120
+ + K+S+S ++N DV+S+ + + ED+++NN
Sbjct: 529 FEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNN 579
Score = 39.3 bits (90), Expect = 0.026
Identities = 108/493 (21%), Positives = 173/493 (35%), Gaps = 56/493 (11%)
Query: 812 SDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEE 871
SDTGS S++ ED G D ND ++ + + L R S EE
Sbjct: 40 SDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEE 99
Query: 872 LKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDEIPRKRPEIWSRSAIV---HSRERENIPR 928
R E N D+ Q S S+ E RK P S + + H+ + EN
Sbjct: 100 --------RAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDV 151
Query: 929 GSVQFA-QEIDQVSSS-ADETEDERSEAENVAENFSISNPAPQQFQGIINLAFEDATENE 986
G + EI+++ S A ++E E + ++++ S P Q E+ +
Sbjct: 152 GKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDS------ENEEPPK 205
Query: 987 CREFSATKKFKRSVLLSVDECEE----LGSDEGEVHTPFQASVDSFSPSDVFDGISHEHH 1042
R + + +S E EE SD P DS S S +
Sbjct: 206 PRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSEN 265
Query: 1043 GRTCYSRFS-RESEDNILECKQNKGNSVCKNESTVLDLSSIDSSRKNK------QSVSAT 1095
R S ESED +N+ + E +S +S K ++ A+
Sbjct: 266 EELPKPRISDSESEDP----PRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDAS 321
Query: 1096 EKKNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQERPCHLDLHQREP 1155
K + R+ ED ++ N S + R KF SD + +E Q+
Sbjct: 322 RHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHK-----KQKMD 376
Query: 1156 NSDIPKNSSTKSLDSFRSQVLPQEGPVKESHSTTTEKANIALS--AGDIDDCDTLAQTRM 1213
+ + K + + ++ VL S S EKA+ S D DD D+ A +
Sbjct: 377 SDEDEKEGEEEKVAKRKAAVL--------SDSEDEEKASAKKSRVVSDADDSDSDAVSDK 428
Query: 1214 YDHRPSKTLSPIYEMDVIEAFEQKVESETHVTDMDFEDDQHFAKQDWTLLKQLLSE--QD 1271
R KT++ E + + K E + F D ++ L+ + E +
Sbjct: 429 SGKR-EKTIASDSEEEAGKELSDKKNEEKDL----FGSDSESGNEEENLIADIFGESGDE 483
Query: 1272 SNLDVTNSVPEDL 1284
+ T EDL
Sbjct: 484 EEEEFTGFNQEDL 496
Score = 35.8 bits (81), Expect = 0.29
Identities = 90/467 (19%), Positives = 165/467 (35%), Gaps = 52/467 (11%)
Query: 691 GRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQED---KKSKVPVEGLTIPSKLSDESAM 747
G D N+Q S V ER + S +ED K V P L+ +
Sbjct: 29 GEDDVNEQHSGSDTGSV-----ERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSE 83
Query: 748 DEDKHATADSDVSS--KCFSGQLSEKNSPKNMETSESPESHETPETPFVGHWNLSTGVLH 805
E+ H DSD S + +N N S+S ES ET + P N H
Sbjct: 84 SEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDS-ESEETRKLPGSDSENEELLNGH 142
Query: 806 QRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSD 865
+S D G S +I+ + + +D S+ H S S+
Sbjct: 143 ASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQ---ASDSE 199
Query: 866 TSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDEIPRKRPEIWSRSAIVHSREREN 925
P + ++ DS K QV+ + +E PR + E E
Sbjct: 200 NEEPPKPRMSDSESEELPKP---------QVSDSESEEPPRHQAS---------DSENEE 241
Query: 926 IPRGSVQFAQEIDQVSSSADETEDER--------SEAENVAENFSISNPAPQQFQGIINL 977
+P+ + ++ D A ++E+E SE+E+ N + + + + ++
Sbjct: 242 LPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSD 301
Query: 978 AFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTPFQASVDSFSPSDVFDGI 1037
+ + + S T+ R + + ++GE D+ +D F
Sbjct: 302 SESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGE---------DTEMQNDSFHSD 352
Query: 1038 SHEHHGRTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLSSIDSSRKNKQSVSATEK 1097
SH + +S S E E + ++ + E +++ S ++++ SA +
Sbjct: 353 SHMDR-KKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKS 411
Query: 1098 KNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQER 1144
+ D S S + DK + +D ++ + SD K++E+
Sbjct: 412 RVVSDADDSDSDAV--SDKSGKREKTIASDSEEEAGKELSDKKNEEK 456
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 45.8 bits (107), Expect = 3e-04
Identities = 118/623 (18%), Positives = 233/623 (37%), Gaps = 80/623 (12%)
Query: 410 RTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHT 469
+T++ PS +T+ + E P+ VK+ V+ +Q+ + K T +K+ + K+
Sbjct: 595 KTETKPS-VTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEK 653
Query: 470 ALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQK 529
PK K VA ++ KK E ++ K+++ ++ + + ++ +K ET K
Sbjct: 654 EKPK---KEVAKKEDKTPIKKEEKPKKEEVKKEVKK-EIKKEEKKEPKKEVKKETPP--K 707
Query: 530 SMFHDVRDNNNKDSVSEQK-PHKPLINLASEISDAEA-LQSSCRPDPQKPLNDQEKEKLA 587
+ +V+ K+ E+K P K + L + + L + +P KP +++E
Sbjct: 708 EVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEE--- 764
Query: 588 LECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFY 647
++ K + E +I + K E K AA +VG+ +
Sbjct: 765 ----SVKKDSVAAGKPKEKGKIKVIKKEGK-----------AAEAVAAAVGTGATTAAVM 809
Query: 648 STTALKYMVSNPN---ENSLNSNP---VCDLDSTSAGQIHLISDRENQVGR-KDTNKQSS 700
+ + + E SL S+P D + A ++ + D + Q+ +D K
Sbjct: 810 AAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKE 869
Query: 701 IKCVEDVSLCNP-ERTNGTLNSAQE---------------DKKSKVPVEGLTIPSKLSDE 744
+ VE + E T G S E ++ V +G+ K DE
Sbjct: 870 TEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDE 929
Query: 745 SAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETSESPESHETPETPFVGHWNLSTGVL 804
A E+ T D + ++ + E++ +++ S S S E +
Sbjct: 930 GAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEAD-----A 984
Query: 805 HQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSS 864
+ RE ES + +D+ E +A S+++ D+ +
Sbjct: 985 YIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAED-------------ARE 1031
Query: 865 DTSTPEELKIYDSNLRIEVKMKKQSN-NDLFQVNSTSDDEIPRKRPEIWSRSAIVHSRER 923
+ PE+++ D + + K + + + +T ++ + P S+I
Sbjct: 1032 EEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSI----HD 1087
Query: 924 ENIPRGSVQFAQEIDQVSSSADETEDERSEAENVAENFSISN-PAPQQFQGIINLAFEDA 982
E +P GS A D+ + D+ E+ + + IS+ P P D
Sbjct: 1088 ETLPGGSESEATASDE-ENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDE 1146
Query: 983 TENE-----CREFSATKKFKRSV 1000
T NE +EF K++ S+
Sbjct: 1147 TNNEETESPSQEFVNITKYESSL 1169
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 45.4 bits (106), Expect = 4e-04
Identities = 98/436 (22%), Positives = 171/436 (39%), Gaps = 58/436 (13%)
Query: 139 KKMKSDGLGASGHSSSTNR--------------NSINKTLKQDDVKEKDGTKIASKITKE 184
K+ K+D G S SS+NR S ++ V KI +I K
Sbjct: 1011 KRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG 1070
Query: 185 LKTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVR 244
GK S T + S + +G K+ + S S++++A+ +G+ +G
Sbjct: 1071 TVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSS-------SSSSSASTSGKMKSSKSEGSS 1123
Query: 245 NQEGQISGARPKVLTGNLNVQAKAKPLKKATGKD-SPCLSIAGPSSRSTDSSMEFSISTE 303
+ + S + +G+ +++K ++ GK S ++ G SS S+ + M+
Sbjct: 1124 SSKLSSSMYSSQGSSGS----SQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPS 1179
Query: 304 CLDEP---KENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGT 360
L P K N S +P G SP + + + S K + P+S + G+
Sbjct: 1180 SLMNPSLSKPNISPSHSRPPGGSDKLA-SPMKPVPGTPPSSKAKS------PISSGSGGS 1232
Query: 361 SNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTK 420
H T+ ++S +K SG G S + Q K +SN CTA+ S+ S+++
Sbjct: 1233 ------HMSGTS-SSSGMKSSSGLGSSGSLSQ---KTPPSSNSCTASSSSFSSSGSSMSS 1282
Query: 421 TQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVA 480
+Q G S S + KL H T + + Q+ + N+
Sbjct: 1283 SQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVS---TNSSSHP 1339
Query: 481 MPKNLNQS----KKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETST-VQKSMF--H 533
M N S + ++KD + G + ++ +S+ K+ ST V K + H
Sbjct: 1340 MSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSES--KNVGSTGVAKIIISKH 1397
Query: 534 DVRDNNNKDSVSEQKP 549
D + K V+ QKP
Sbjct: 1398 DGGSPSIKAKVTLQKP 1413
Score = 31.2 bits (69), Expect = 7.1
Identities = 137/686 (19%), Positives = 233/686 (33%), Gaps = 128/686 (18%)
Query: 486 NQSKKGETLNNKDSKQ-KMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSV 544
N + G L++K K+ + P SK +P P + + T KS H
Sbjct: 980 NSTLSGPGLDSKPGKRSRTPSNDGKSKDKP----PKRKKADTEGKSPSHS---------- 1025
Query: 545 SEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALEC-QNISKLDKSLKHE 603
S +P P + S A +S P P K+ ++ + + K H
Sbjct: 1026 SSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATP----PIPKITIQIPKGTVMVGKPSSHS 1081
Query: 604 LESKQICLDKSETKFPNHKETDDCDAANIC--CHSVGSDNVNSKFYSTTALKYMVSNPNE 661
+ + S +K + + +A+ S S+ +S S++ S+ +
Sbjct: 1082 QYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSS 1141
Query: 662 NSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNS 721
S NS+ +S H +S + K K SS+ + SL P +
Sbjct: 1142 QSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLM---NPSLSKPNISPSHSRP 1198
Query: 722 AQEDKKSKVPVEGL--TIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMET 779
K P++ + T PS + A S +SS +S +S M++
Sbjct: 1199 PGGSDKLASPMKPVPGTPPS-------------SKAKSPISSGSGGSHMSGTSSSSGMKS 1245
Query: 780 SESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDD 839
S +G S+G L Q+ P S++ +A++SS + + GS
Sbjct: 1246 SSG-----------LG----SSGSLSQKTPPSSNSCTASSSS---------FSSSGSSMS 1281
Query: 840 DGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVN-- 897
N G SK G+S S P + D L+ V D
Sbjct: 1282 SSQNQHGSSK----------GKSPSRNKKPSLTAVID-KLKHGVVTSGPGGEDPLDGQMG 1330
Query: 898 -STSDDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAEN 956
ST+ P S RE+ + + V S S+ ++ + SE++N
Sbjct: 1331 VSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV-------STSGSSVDSSKKTSESKN 1383
Query: 957 VAENFSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGE 1016
V G+ + + + K V L ++ G GE
Sbjct: 1384 VGST------------GVAKIIIS-------KHDGGSPSIKAKVTL-----QKPGESSGE 1419
Query: 1017 VHTPFQASVDSFSPSDVFDGISHEH-HGRTCYSRFSRESEDNILECKQNKGNSVCKNEST 1075
P AS ++ S + G + +H G +S+ + N L+ + G+S+ + +S
Sbjct: 1420 GLRPQMASSKNYG-SPLISGSTPKHERGSPSHSKSPAYTPQN-LDSESESGSSIAE-KSY 1476
Query: 1076 VLDLSSIDSSR------KNKQSVSATEKKNTIDVLSSRSRQLLREDKKVN-------NGS 1122
SS D R K EKK D R R R+ KK + + S
Sbjct: 1477 QNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKS 1536
Query: 1123 NVENDIQQRSKFLDSDVKSQERPCHL 1148
+ +D Q + + S +RP L
Sbjct: 1537 PISSD--QSLSMTSNTILSADRPSRL 1560
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 45.4 bits (106), Expect = 4e-04
Identities = 59/300 (19%), Positives = 101/300 (33%), Gaps = 16/300 (5%)
Query: 148 ASGHSSSTNRNSINKTLKQDDVKEKDGTKIASKITKELKTGGKNVSGKPKTVTKSKTENG 207
+SG S++TN +S + D + +S+ + + S T T S++
Sbjct: 129 SSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTV 188
Query: 208 DKARLENMSPRQVVERSATAAAAATGQKNLLNGKG-VRNQEGQISGARPKVLTGNLNVQA 266
+ S + A + + NG G N E + + T + +
Sbjct: 189 SSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTP 248
Query: 267 KAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSF 326
+ + S S AG ++ S S++ IST ++E PS +
Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVT--------NSESSTPSSGANTA 300
Query: 327 CDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGC 386
+S + ++ NS + S S TN S+ S + NS S
Sbjct: 301 TNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTS--SGASTATNSESSTTSSGAS 358
Query: 387 SEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGES-----PNSVKSSVSSRQS 441
+ + GTS + S S T ++ S S NS S+VSS S
Sbjct: 359 TATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGAS 418
Score = 35.4 bits (80), Expect = 0.37
Identities = 52/258 (20%), Positives = 90/258 (34%), Gaps = 24/258 (9%)
Query: 221 VERSATAAAAATGQKNLLNGKG-VRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDS 279
V S + A +G NG V N E + + T N + + AT +S
Sbjct: 52 VTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTAT-NSEFSTVSSGISIATNSES 110
Query: 280 PCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVD 339
S ++ +++SS S ++ + S+ + S S NS
Sbjct: 111 STTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSES 170
Query: 340 SVKNS-----TVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAI 394
S +S T + S SR + T+++ S + + + + G
Sbjct: 171 STTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNS-- 228
Query: 395 LKKRGTSNGCTAAQQRTKSTPSN---------LTKTQGSQGESPNSVKSSVSS-----RQ 440
+ TS+G + A STPS+ + T G + NS S+VSS
Sbjct: 229 -ESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTN 287
Query: 441 SDENVAKLDHNTTTEKQA 458
S+ + NT T ++
Sbjct: 288 SESSTPSSGANTATNSES 305
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 45.1 bits (105), Expect = 5e-04
Identities = 191/1025 (18%), Positives = 376/1025 (36%), Gaps = 166/1025 (16%)
Query: 307 EPKENGSTEEEKPSGHK-----LSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTS 361
E ++ S EKP G K S+ +P ++ ++ V ++K + ++ +
Sbjct: 13 ENSDSDSNMVEKPYGRKSKDKIASYSKTP-KIERSDVSKEMKEKSSMKRKLPFTISPSRN 71
Query: 362 NKKSIHEQDTNVNNSVLKKVSGKGCSEPV------PQAILKKRGTSNGCTAAQQRTKSTP 415
++ + KK +G S PV P + K+ TA STP
Sbjct: 72 EERDSDTEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTP 131
Query: 416 SNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTAL---P 472
++ ++T +Q ++P+S SSRQ D+ + + T A R VKQV +
Sbjct: 132 NHPSQTTPAQKKTPSS-----SSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGA 186
Query: 473 KVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMF 532
VN K A L+++ + +K + G ++ PL S+ + +
Sbjct: 187 NVNVKDFAGWTPLHEACNVGYYD--VAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIV 244
Query: 533 HDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEK---EKLALE 589
+ + + + +P+ ++++ E L+ + + PL+D ++ + +
Sbjct: 245 KLLLRHGGNPFQANKHGERPV-----DVAETEELELLLK--REVPLSDDDESYTDSEEAQ 297
Query: 590 CQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYST 649
N S +D+++ E E K++ C++ I + SK
Sbjct: 298 SVNPSSVDENIDSETE----------------KDSLICESKQI---------LPSKTPLP 332
Query: 650 TAL-KYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVS 708
+AL +Y + ++ +N +I DR + RK+ K++ + +
Sbjct: 333 SALDEYEFKDDDDEEINK---------------MIDDR--HILRKEQRKENEPEAEKTHL 375
Query: 709 LCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHA--------TADSDVS 760
E+ + + KK K P L ++ SDE A+ K + T++SD+
Sbjct: 376 FAKQEK--AFYPKSFKSKKQK-PSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQ 432
Query: 761 SK---CFSGQLSE--------KNSPKNMETSESPESHETPETPFVGHWNLSTGV-LHQRE 808
+K SG+ + KN KN E E + E E + + ++TG+ ++
Sbjct: 433 TKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKT 492
Query: 809 SPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSDTST 868
E + + + DD G S CG L S
Sbjct: 493 REEGNFRKSFSPKDDTSLHLFHISTGKSPK---------HSCG-------LSEKQSTPLK 536
Query: 869 PEELKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDEIPRKRPEIWSRSAIVHSRERENIPR 928
E K S E+ ++ DL + ++T + +P S+ V S + + +
Sbjct: 537 QEHTKTCLSPGSSEMSLQP----DLVRYDNTESEFLP--------ESSSVKSCKHKEKSK 584
Query: 929 GSVQFAQEIDQVSSSADETEDERSEAENVAENFSISNPAPQQFQGIINLAFEDATENECR 988
F E + S++ + ED EN + + + E E +
Sbjct: 585 HQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKK 644
Query: 989 EFSATK-KFKRSVLLSVDECEELGSDEGEVHTPFQASVDSFSPSDVFDG--ISHEHHGRT 1045
E K K+K + D +EL + V + ++F SD + ++ EH T
Sbjct: 645 EIEGEKEKYK-----TKDSAKEL---QRSVEFDREFWKENFFKSDETEDLFLNMEHESLT 696
Query: 1046 CYSRFSRESEDNILECKQNKGNSVCKNESTVLDLSSIDSSRKNKQSVSATEKKNTIDVLS 1105
+ + E NI + K K V K + + I K+S + ++ D+
Sbjct: 697 LEKK--SKLEKNIKDDKSTKEKHVSKERNFKEERDKI-----KKESEKSFREEKIKDLKE 749
Query: 1106 SRSRQLLREDKKVNN--GSNVENDIQQRSKFLDSDVKSQERPCHLDLHQREPNSDIPKNS 1163
R +D + + S +E I + D++ QE+ + E S I +
Sbjct: 750 ERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKE-- 807
Query: 1164 STKSLDSFRSQVLPQEGPVKESHSTTTEKANIALSAGDIDDCDTLAQTRMYDH------- 1216
K ++ + +E +K H + +K +++ I + D ++Y H
Sbjct: 808 --KDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKD-----KLYSHHTEKCHK 860
Query: 1217 --RPSKTLSPIYEMDVIEAFEQKVESETHVTDMDFEDDQHFAKQDWTLLKQLLSEQDSNL 1274
SK + I + D E +K++ + H + E ++H A+ L + ++Q N
Sbjct: 861 EGEKSKNTAAIKKTDDREKSREKMDRK-HDKEKP-EKERHLAESKEKHLMEKKNKQSDNS 918
Query: 1275 DVTNS 1279
+ + S
Sbjct: 919 EYSKS 923
Score = 41.6 bits (96), Expect = 0.005
Identities = 127/695 (18%), Positives = 249/695 (35%), Gaps = 118/695 (16%)
Query: 156 NRNSINKTLKQDDVKEKDGTKIASKITKELKTGG-KNVSGKPKTVTKSKTENGDKARLEN 214
+R+ + K ++++ E + T + +K K K+ KP V S TE+ D+ L+N
Sbjct: 354 DRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQN 413
Query: 215 --MSPRQVVERSATAAAAATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLK 272
+S V + + T ++ +++G+ Q+G++ + K+ N N + + +
Sbjct: 414 KKISTSCSVIPETSNSDMQTKKEYVVSGE--HKQKGKV---KRKLKNQNKNKENQELKQE 468
Query: 273 KATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEE---KPSGHKLSFCDS 329
K GK++ + +++ + +C ++ +E G+ + K F S
Sbjct: 469 K-EGKENTRI-----------TNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHIS 516
Query: 330 PGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEP 389
G+ K+S + + +K + S++ S+ +N+ SE
Sbjct: 517 TGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTE---------SEF 567
Query: 390 VPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGS------QGESPNSVKSSVSSRQSDE 443
+P++ + C ++ +L + S + SP S + ++ D+
Sbjct: 568 LPES-----SSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDK 622
Query: 444 NVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKN------------------- 484
L + K+ K K K++ K K A
Sbjct: 623 EGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDE 682
Query: 485 -----LNQSKKGETLNNKDSKQK-MPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDN 538
LN + TL K +K + + + S +R K E ++K R+
Sbjct: 683 TEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE 742
Query: 539 NNKDSVSEQKPHKP----------------------LINLASEISDAEALQSSCRPDPQK 576
KD + E++ + P L+ +I E + P+K
Sbjct: 743 KIKD-LKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEK 801
Query: 577 PLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCDAANI-CCH 635
+EK+ +E + K +K +KHE +S++ LD SE KE D + + CH
Sbjct: 802 RSQIKEKDIEKMERKTFEK-EKKIKHEHKSEKDKLDLSEC-VDKIKEKDKLYSHHTEKCH 859
Query: 636 SVGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDT 695
G + N T A+K ++ E S + HL +E + K
Sbjct: 860 KEGEKSKN-----TAAIK--KTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEK-K 911
Query: 696 NKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATA 755
NKQS ++ E+ + DKK K S+ + + KH
Sbjct: 912 NKQS-----DNSEYSKSEKGKNKEKDRELDKKEK---------SRDKESINITNSKH--I 955
Query: 756 DSDVSSKCFSGQLSEKNSPKNMETSESPESHETPE 790
+ S G ++ P +++ E +TP+
Sbjct: 956 QEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPD 990
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 43.9 bits (102), Expect = 0.001
Identities = 103/444 (23%), Positives = 157/444 (35%), Gaps = 66/444 (14%)
Query: 118 IKIKSWRGNNKKECWSYLSTNKKM-KSDGLGASGHSSST---NRNSINKTLKQDDVKEKD 173
I IK RGN +K T + K L S SSST + +SI L Q D
Sbjct: 960 ILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMT 1019
Query: 174 GTKIASKITK---ELKTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAA 230
++AS + K +L K+ S K K++ + D + PR ++ AA
Sbjct: 1020 DKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPR--IKHVCRRAAV 1077
Query: 231 ATGQKNLLNGKGVRNQEGQISGARPKVLT--GNLNVQAKA------------KPLKKATG 276
A G+K + + R K+L+ GN + + A KP+K T
Sbjct: 1078 ALGRKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTR 1137
Query: 277 KDSPCLSIAGPSSRSTDSSM--------EFSISTECLDEPKENGSTEEEKPSGHKLSFCD 328
+P RS + + T CLD+PK G K K+ C
Sbjct: 1138 NKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGG--RNIKKQCCKMRKCQ 1195
Query: 329 SPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDT--NVNNSVLKKVSG--- 383
+ Q M + K + K S+ TS KK E NV +S K
Sbjct: 1196 NL-QWMPSKAYLQKQAKAVKKKEKKSK----TSEKKDSKESSVVKNVVDSSQKPTPSARE 1250
Query: 384 -----KGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSV--KSSV 436
K SEP P+ ++++ +A +K + ++ Q P V
Sbjct: 1251 DPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPP 1310
Query: 437 SSRQSDENVAKLDHNTTTEKQAP---------KRKMVKQVHTALPKVNAKIVAMPKNLNQ 487
++ + V K + +KQ P K+K V + K K P +N+
Sbjct: 1311 TTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNK 1370
Query: 488 SKKGETL-------NNKDSKQKMP 504
+ TL N SKQK+P
Sbjct: 1371 QENAGTLNILSTLSNGNSSKQKIP 1394
Score = 35.0 bits (79), Expect = 0.49
Identities = 80/418 (19%), Positives = 154/418 (36%), Gaps = 45/418 (10%)
Query: 190 KNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSA-------------TAAAAATGQKN 236
++V G T + T + D + L + S + S+ T++A+ G
Sbjct: 3304 QSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVPGHVT 3363
Query: 237 LLNGKGVRNQE-GQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSS 295
L N + + + G IS K +L +Q + L ++G + PS+ + ++
Sbjct: 3364 LTNPRLLGTPDIGSISNLLIKASQQSLGIQDQPVALPPSSGMFPQLGTSQTPSTAAITAA 3423
Query: 296 MEF----SISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSR 351
S T + +G +E H S K + S + +
Sbjct: 3424 SSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLAS-----KTGIHSSQRDLDSASGP 3478
Query: 352 PVSRVTNGTSNKKSIH-EQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTS-NGCTAAQQ 409
VS T S+ EQ+ ++++V + G S P + + S G T +
Sbjct: 3479 QVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKP 3538
Query: 410 RTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHT 469
+TK L K G + + + SS + D+ L T T P + +Q
Sbjct: 3539 KTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGT----PGAEAEQQDTA 3594
Query: 470 ALPKVNAKIVAMPKN-LNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQ 528
++ + + K P + + + N ++Q+ + + + + + PL
Sbjct: 3595 SVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPL-------- 3646
Query: 529 KSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQ--SSCRPDPQKPLNDQEKE 584
M ++ K+S++E+KP K L+ EIS + Q + D K L D+ +E
Sbjct: 3647 --MLWLQQEQKRKESITEKKPKKGLV---FEISSDDGFQICAESIEDAWKSLTDKVQE 3699
Score = 33.1 bits (74), Expect = 1.9
Identities = 70/365 (19%), Positives = 135/365 (36%), Gaps = 47/365 (12%)
Query: 172 KDGTKIASKITKELKTGGKNVSGKPKTVTKSK---TENGDKARLENMSPRQVVERSATAA 228
K TK KI K+ + G+P T K T D + L + +++
Sbjct: 201 KSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTP 260
Query: 229 AAATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPS 288
+A Q + + + G++S + K TG L + K + + G+ I PS
Sbjct: 261 SATFQQATKIK----KLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPS 316
Query: 289 SRSTDSSMEFSISTECLDEPKENGSTEEEKP---SGHKLSFCDSPGQMMK-NSVDSVKNS 344
+S +E +P++ +E P K SP ++ + S K +
Sbjct: 317 GLLINSELE---------KPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRIIPSSKRT 367
Query: 345 TVAIKSRPVSRVTNGTSNK----------KSIHEQDTNVNNSVLKKVSG-KGCSEPVPQA 393
I + + R G K + + Q N+ ++ VS P+
Sbjct: 368 DATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRR 427
Query: 394 ILKKRGTSNGCTAAQQRTK-----STPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKL 448
++ A+ + S PS + + S +S SS SSR S +V
Sbjct: 428 FIEDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSV--- 484
Query: 449 DHNTTTEKQAPKR-KMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQ 507
+T+T+ QA + +++ + + P+V+ P ++QS + E+ + + + +
Sbjct: 485 --DTSTDSQASEEIQVLPEERSDTPEVHP-----PLPISQSPENESNDRRSRRYSVSERS 537
Query: 508 VISKT 512
S+T
Sbjct: 538 FGSRT 542
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 43.5 bits (101), Expect = 0.001
Identities = 63/319 (19%), Positives = 122/319 (38%), Gaps = 12/319 (3%)
Query: 287 PSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTV 346
PS S D++ E S +++ KE+ E+P S S ++ + S K+++
Sbjct: 177 PSHGSKDANKESSKTSKPHKVTKEH----RERPRKDSESKSSSK-ELEREQAKSSKDTSR 231
Query: 347 AIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTA 406
+ + + K + E + + L+ S KG P P + + TA
Sbjct: 232 KLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKG-GPPPPPPPPPRASSKRPATA 290
Query: 407 AQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQ 466
+ + + ++GS+ S ++S SS SD+ AK D ++T ++ ++
Sbjct: 291 DSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAK-DKSSTRGEKVKAESEPRE 349
Query: 467 VHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETST 526
AL + ++S + N+ S +Q SQ PL+
Sbjct: 350 AKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSD-FEPSQNHSQGPLRSMVED 408
Query: 527 VQKSMFHDVRDNNNKDSVSEQKPHK----PLINLASEISDAEALQSSCRPDPQKPLNDQE 582
+Q + ++ +++ + P + + S+ S +L S P PQKP
Sbjct: 409 LQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNS 468
Query: 583 KEKLALECQNISKLDKSLK 601
K ++ SK +K LK
Sbjct: 469 KVSGRRSPESCSKPEKILK 487
Score = 35.0 bits (79), Expect = 0.49
Identities = 51/246 (20%), Positives = 94/246 (38%), Gaps = 36/246 (14%)
Query: 657 SNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTN 716
+ P+ S ++N +S+ + H ++ + RKD+ +SS K +E + + T+
Sbjct: 175 TKPSHGSKDANK----ESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTS 230
Query: 717 GTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKN 776
L + K+ K P P K +A E K A ++ + S G P
Sbjct: 231 RKLGEGRLPKEEKAP------PPK----AAFKEPKMALKETKLESTSPKGGPPPPPPPPP 280
Query: 777 METSESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGS 836
+S+ P + ++P+ P S+ + S S+++S D KP
Sbjct: 281 RASSKRPATADSPK-PSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAK-------- 331
Query: 837 QDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQV 896
D S+ RG + + S + L++ +SN E K +S
Sbjct: 332 ---DKSSTRG----------EKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSN 378
Query: 897 NSTSDD 902
+S+S D
Sbjct: 379 SSSSSD 384
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 43.1 bits (100), Expect = 0.002
Identities = 66/304 (21%), Positives = 123/304 (40%), Gaps = 47/304 (15%)
Query: 297 EFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRV 356
E STE ++ + +T KP+ D P K ++D K+ST ++ P S
Sbjct: 73 ELPKSTEIHEQKRHCNTTRHSKPT-------DKPTGNSK-TIDH-KSSTDNHEAPPTSEE 123
Query: 357 TNGTSNKKSIHEQDTNVN----NSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTK 412
+ K + +V+ + K+ +GK P P++ + R ++ G + +++
Sbjct: 124 NSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSD 183
Query: 413 STPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALP 472
T L K+ + K+S SS H TTT KQ T+ P
Sbjct: 184 KTGRPLEKSMSTLD------KTSTSS-----------HKTTTSFHNSGNSQTKQKSTSFP 226
Query: 473 KVNAKIVAMPKNLNQS--KKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHE--TSTVQ 528
+ KI A K ++ E+ +DS+ + ++++KT + Q + T ++
Sbjct: 227 E---KITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLA 283
Query: 529 KSMFHDVRDNNNKDSVSEQKPHKPLINLASE---ISDAEALQSSCR-------PDPQKPL 578
+ H R N ++ S +P + A+E +S AE +++ R P P P
Sbjct: 284 EPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPT 343
Query: 579 NDQE 582
++E
Sbjct: 344 ENRE 347
Score = 38.9 bits (89), Expect = 0.034
Identities = 138/758 (18%), Positives = 254/758 (33%), Gaps = 133/758 (17%)
Query: 186 KTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKN-LLNGKGVR 244
+T +N + P TE+G++ EN +P + A G++ N K
Sbjct: 367 RTANENTTPSPA----EPTEHGERTANENTTP-------SPAEPTEHGERTPFANDKTTS 415
Query: 245 NQEGQISGARPKVLTGNLNVQAKAKPL--KKATGKDSPCLSIAGPS-SRSTDSSMEFSIS 301
+ L + A+P ++ T ++ S AGP+ +R T ++ + ++S
Sbjct: 416 SSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLS 475
Query: 302 TECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDS--VKNSTVAIKSRPVS---RV 356
E +E + E+ PS P + +N + T + + P R
Sbjct: 476 PVEPTENRETTANEKTTPS---------PAEPTENGQRTPFANEKTTSSSAEPTEHGERT 526
Query: 357 TNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPS 416
N + T + + +EP T NG K+TPS
Sbjct: 527 PLANENTTPSPAEPTENRERTANEKTTPSPAEP----------TENGDRTPLANEKTTPS 576
Query: 417 NLTKTQGSQG---ESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAP---KRKMVKQVHTA 470
T+ Q + + SS + +E + NTT P + + + T
Sbjct: 577 LAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTP 636
Query: 471 LP---------KVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQ-------VISKTQP 514
P N K P ++++ T N K + P + KT
Sbjct: 637 SPAGPTENREMTANEKTTLFPAEPTENRE-RTANEKTTSSPAEPTENGQRTPFANEKTTS 695
Query: 515 SSQRPLKHETSTV---QKSMFHDVRDNNNKDSVSEQK----PHKPLINLASEISDAEALQ 567
SS P +H T + + N++ + +K P +P N ++
Sbjct: 696 SSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANE----- 750
Query: 568 SSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDC 627
+ P P +P + ++ LA E K SL E+ + T F N K T
Sbjct: 751 -NTTPSPAQPTENGDRTPLANE-----KTTPSLAEPTENGK------RTPFANEKTTS-- 796
Query: 628 DAANICCHS----VGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLI 683
+A H+ + ++N S T + +N + P + +ST+ +
Sbjct: 797 SSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPF 856
Query: 684 SDRENQVGRKDTNKQSSIKCVEDVS------LCNPERT--------NGTLNSAQEDK--- 726
+ N+ +++ E L N + T NG +K
Sbjct: 857 PAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTP 916
Query: 727 KSKVPVE---------GLTIPSKL--SDESAMDEDKHATADSDVSSKCFSGQLSEKNSPK 775
S P E +T PS+ ++ ++ AT ++ ++E +P
Sbjct: 917 SSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPS 976
Query: 776 NMETSESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGG 835
+ E +E+ E TP N +T E E TT S +E + G
Sbjct: 977 SAEPTENGE-----RTPLANE-NTTTSPTESTEHGERTANEKTTPSP-----AEPTEHG- 1024
Query: 836 SQDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELK 873
+ +N++ I H+ + S+++ +TP +K
Sbjct: 1025 -ERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVK 1061
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 43.1 bits (100), Expect = 0.002
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 47/417 (11%)
Query: 373 VNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSV 432
VN+ +K++ +E + +LK G N + S+ S+ + + S S +S
Sbjct: 114 VNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSS 173
Query: 433 KSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGE 492
SS SS S + +++T P K++K+ H P +++ ++ + K+
Sbjct: 174 SSSSSSSSSSSS----SSSSSTSFSKP-HKLMKE-HKEKPSKDSR-----EHKSAFKEPS 222
Query: 493 TLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKP 552
+NK SK+ S +P +PLK E V K F + K E KP
Sbjct: 223 RDHNKSSKE--------SSKKPKENKPLKEE-KIVPKMAFKE-----PKPMSKEPKPDSN 268
Query: 553 LINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLD 612
L+ + S Q P + P++D E+L+ + + S + K + + L
Sbjct: 269 LLTITSG-------QDKKAPSKRPPISD--SEELSAKKRKKSSSEALFKSFSSAPPLILT 319
Query: 613 KSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDL 672
S K K+ D + + S+ + K ST + +PN++ + N
Sbjct: 320 CSADK----KQIKDKSHVKMGKVKIESE-TSEKKKSTLPPFDDIVDPNDSDVEENISSKS 374
Query: 673 DSTSAGQIHLISDRENQVGRKDTNKQSSIKCV-EDVSLCNPERTNGTLNSAQEDKKSKVP 731
DS S + T +Q ++ + +D+ + E + + D + + P
Sbjct: 375 DSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERP 434
Query: 732 VEGLTIPSKLSDESAMDEDKHATADSDVSS-------KCFSGQLSEKNSPKNMETSE 781
V S+ S + + ++A S + K + Q+ E SP S+
Sbjct: 435 VNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSD 491
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 43.1 bits (100), Expect = 0.002
Identities = 82/438 (18%), Positives = 169/438 (38%), Gaps = 49/438 (11%)
Query: 136 STNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASKITKELKTGGKNVSGK 195
+ ++K ++ G S N++S +K K + K +S+ K+ K K+ K
Sbjct: 18 ANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKK 77
Query: 196 PKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVRNQ--EGQISGA 253
K + E D + E MSP + + A ++ L + N+ EG++
Sbjct: 78 HK-----RKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSG 132
Query: 254 RPKVLTGNLNVQAKAKPL--KKATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKEN 311
+L G + + + K G S S+RS+ + + + + K +
Sbjct: 133 MGLILQGYESGSEEEGEIHEKARNGNRS--------STRSSSTKGKLELVDNKITTKKRS 184
Query: 312 GSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDT 371
S +E+ + H+ S + K ++ VK T KS+ + + + KS +Q
Sbjct: 185 KSRSKER-TRHR-----SDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKS-QDQAR 237
Query: 372 NVNNSVLKKVS----GKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQ--GSQ 425
+ L++ S GK S + ++ + S + R KS N ++++ G +
Sbjct: 238 KSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKS------KDRKKSPIINESRSRDRGKK 291
Query: 426 GESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTAL------------PK 473
SP ++ R+S K + T +++ P + K + PK
Sbjct: 292 SRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPK 351
Query: 474 VNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFH 533
+ P++ ++ + LN++ SKQ P + +S + + R L+ + ++
Sbjct: 352 -RRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLS 410
Query: 534 DVRDNNNKDSVSEQKPHK 551
R D +S ++ K
Sbjct: 411 SPRTRPRDDILSRRERSK 428
Score = 32.3 bits (72), Expect = 3.2
Identities = 89/448 (19%), Positives = 164/448 (36%), Gaps = 70/448 (15%)
Query: 687 ENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLN---SAQEDKKSKVPVEGLTIPSKLSD 743
+ ++G+ + +K +ED S + + +N S KKS+ PV+ + K D
Sbjct: 249 QEKIGKARSPTDDKVK-IEDKSKSKDRKKSPIINESRSRDRGKKSRSPVD---LRGKSKD 304
Query: 744 E-SAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMET-----SESPESHETPETPFVGHW 797
S E K +++D K + +S K + SP+ P
Sbjct: 305 RRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSR 364
Query: 798 NLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHD 857
+ +L+ R S +S + S T S + +S + + + R +S T D
Sbjct: 365 RSRSPLLNDRRSKQSKSPSRTLSPGR-RAKSRSLERKRREPER----RRLSSPRTRPRDD 419
Query: 858 FLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNST---------------SDD 902
L R + + R ++++S + L + S S
Sbjct: 420 ILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRS 479
Query: 903 EIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETED---ERSEAENVAE 959
+ R+ R S+ +E+ +GS+ +++Q SSS D ED E + E + E
Sbjct: 480 RLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIE 539
Query: 960 NFSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDE-CEELGSDEGEVH 1018
I A Q + ED+ + E S+ + R+ S D+ E + +D E
Sbjct: 540 QRRIQRQAIVQKYKYL---AEDSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYE 596
Query: 1019 TPFQASVDSFSPSDVFDGISHEHHGRTCYSRFSRESEDNILECKQNKGNSVCK------- 1071
+ +VD+F S +++ N++ +QN G+S K
Sbjct: 597 ---RENVDTFEA--------------------SVKAKHNLMTVEQNNGSSQKKLLAPDMF 633
Query: 1072 NESTVLDLSSIDSSRKNKQSVSATEKKN 1099
ES + + DS+R + K+N
Sbjct: 634 TESDDMFAAYFDSARLRAAGIGKDFKEN 661
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 42.4 bits (98), Expect = 0.003
Identities = 198/1060 (18%), Positives = 385/1060 (36%), Gaps = 170/1060 (16%)
Query: 269 KPLKKATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCD 328
KP++ + DS + P R + + T ++ + +E+ KL F
Sbjct: 8 KPIQ-SENSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTI 66
Query: 329 SPGQMMKNSVDSVKN--------STVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKK 380
SP + + D+ + I S G KK+ E N ++ +
Sbjct: 67 SPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAG-NKKSTPVSI 125
Query: 381 VSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQ 440
+ G SE A+L + TA STP++ ++T +Q ++P+S SSRQ
Sbjct: 126 LFGYPLSERKQMALLMQM------TARDNSPDSTPNHPSQTTPAQKKTPSS-----SSRQ 174
Query: 441 SDENVAKLDHNTTTEKQAPKRKMVKQVHTAL---PKVNAKIVAMPKNLNQSKKGETLNNK 497
D+ + + T A R VKQV + VN K A L+++ +
Sbjct: 175 KDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYD-- 232
Query: 498 DSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLA 557
+K + G ++ PL S+ + + + + + + +P+
Sbjct: 233 VAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPV---- 288
Query: 558 SEISDAEALQSSCRPDPQKPLNDQEK---EKLALECQNISKLDKSLKHELESKQICLDKS 614
++++ E L+ + + PL+D ++ + + N S +D+++ E E
Sbjct: 289 -DVAETEELELLLK--REVPLSDDDESYTDSEEAQSVNPSSVDENIDSETE--------- 336
Query: 615 ETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTAL-KYMVSNPNENSLNSNPVCDLD 673
K++ C++ I + SK +AL +Y + ++ +N
Sbjct: 337 -------KDSLICESKQI---------LPSKTPLPSALDEYEFKDDDDEEINK------- 373
Query: 674 STSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVE 733
+I DR + RK+ K++ + + E+ + + KK K P
Sbjct: 374 --------MIDDR--HILRKEQRKENEPEAEKTHLFAKQEK--AFYPKSFKSKKQK-PSR 420
Query: 734 GLTIPSKLSDESAMDEDKHA--------TADSDVSSK---CFSGQLSE--------KNSP 774
L ++ SDE A+ K + T++SD+ +K SG+ + KN
Sbjct: 421 VLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQN 480
Query: 775 KNMETSESPESHETPETPFVGHWNLSTGV-LHQRESPESDTGSATTSSDDIKPRSEDYDA 833
KN E E + E E + + ++TG+ ++ E + + + DD
Sbjct: 481 KNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHIST 540
Query: 834 GGSQDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDL 893
G S CG L S E K S E+ ++ DL
Sbjct: 541 GKSPK---------HSCG-------LSEKQSTPLKQEHTKTCLSPGSSEMSLQP----DL 580
Query: 894 FQVNSTSDDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSE 953
+ ++T + +P S+ V S + + + F E + S++ + ED
Sbjct: 581 VRYDNTESEFLP--------ESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPT 632
Query: 954 AENVAENFSISNPAPQQFQGIINLAFEDATENECREFSATK-KFKRSVLLSVDECEELGS 1012
EN + + + E E +E K K+K + D +EL
Sbjct: 633 FENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYK-----TKDSAKEL-- 685
Query: 1013 DEGEVHTPFQASVDSFSPSDVFDG--ISHEHHGRTCYSRFSRESEDNILECKQNKGNSVC 1070
+ V + ++F SD + ++ EH T + + E NI + K K V
Sbjct: 686 -QRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKK--SKLEKNIKDDKSTKEKHVS 742
Query: 1071 KNESTVLDLSSIDSSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNN--GSNVENDI 1128
K + + I K+S + ++ D+ R +D + + S +E I
Sbjct: 743 KERNFKEERDKI-----KKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESI 797
Query: 1129 QQRSKFLDSDVKSQERPCHLDLHQREPNSDIPKNSSTKSLDSFRSQVLPQEGPVKESHST 1188
+ D++ QE+ + E S I + K ++ + +E +K H +
Sbjct: 798 GLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKE----KDIEKMERKTFEKEKKIKHEHKS 853
Query: 1189 TTEKANIALSAGDIDDCDTLAQTRMYDH---------RPSKTLSPIYEMDVIEAFEQKVE 1239
+K +++ I + D ++Y H SK + I + D E +K++
Sbjct: 854 EKDKLDLSECVDKIKEKD-----KLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMD 908
Query: 1240 SETHVTDMDFEDDQHFAKQDWTLLKQLLSEQDSNLDVTNS 1279
+ H + E ++H A+ L + ++Q N + + S
Sbjct: 909 RK-HDKEKP-EKERHLAESKEKHLMEKKNKQSDNSEYSKS 946
Score = 41.6 bits (96), Expect = 0.005
Identities = 127/695 (18%), Positives = 249/695 (35%), Gaps = 118/695 (16%)
Query: 156 NRNSINKTLKQDDVKEKDGTKIASKITKELKTGG-KNVSGKPKTVTKSKTENGDKARLEN 214
+R+ + K ++++ E + T + +K K K+ KP V S TE+ D+ L+N
Sbjct: 377 DRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQN 436
Query: 215 --MSPRQVVERSATAAAAATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLK 272
+S V + + T ++ +++G+ Q+G++ + K+ N N + + +
Sbjct: 437 KKISTSCSVIPETSNSDMQTKKEYVVSGE--HKQKGKV---KRKLKNQNKNKENQELKQE 491
Query: 273 KATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEE---KPSGHKLSFCDS 329
K GK++ + +++ + +C ++ +E G+ + K F S
Sbjct: 492 K-EGKENTRI-----------TNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHIS 539
Query: 330 PGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEP 389
G+ K+S + + +K + S++ S+ +N+ SE
Sbjct: 540 TGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTE---------SEF 590
Query: 390 VPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGS------QGESPNSVKSSVSSRQSDE 443
+P++ + C ++ +L + S + SP S + ++ D+
Sbjct: 591 LPES-----SSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDK 645
Query: 444 NVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKN------------------- 484
L + K+ K K K++ K K A
Sbjct: 646 EGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDE 705
Query: 485 -----LNQSKKGETLNNKDSKQK-MPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDN 538
LN + TL K +K + + + S +R K E ++K R+
Sbjct: 706 TEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE 765
Query: 539 NNKDSVSEQKPHKP----------------------LINLASEISDAEALQSSCRPDPQK 576
KD + E++ + P L+ +I E + P+K
Sbjct: 766 KIKD-LKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEK 824
Query: 577 PLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCDAANI-CCH 635
+EK+ +E + K +K +KHE +S++ LD SE KE D + + CH
Sbjct: 825 RSQIKEKDIEKMERKTFEK-EKKIKHEHKSEKDKLDLSEC-VDKIKEKDKLYSHHTEKCH 882
Query: 636 SVGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDT 695
G + N T A+K ++ E S + HL +E + K
Sbjct: 883 KEGEKSKN-----TAAIK--KTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEK-K 934
Query: 696 NKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATA 755
NKQS ++ E+ + DKK K S+ + + KH
Sbjct: 935 NKQS-----DNSEYSKSEKGKNKEKDRELDKKEK---------SRDKESINITNSKH--I 978
Query: 756 DSDVSSKCFSGQLSEKNSPKNMETSESPESHETPE 790
+ S G ++ P +++ E +TP+
Sbjct: 979 QEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPD 1013
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 42.4 bits (98), Expect = 0.003
Identities = 168/827 (20%), Positives = 292/827 (35%), Gaps = 177/827 (21%)
Query: 136 STNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASK--ITKELKTGGKNVS 193
S+ K K G HS S + K +K++ VK+ + S+ TKE K N
Sbjct: 1043 SSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEK 1102
Query: 194 GKP------KTVTKSKTENGDK---------ARLE-----NMSPRQVVE----------- 222
KP K K++ + DK ++LE SP++ +E
Sbjct: 1103 NKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPE 1162
Query: 223 --RSATAAAAATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLK-----KAT 275
+ + +A A + N GK + + E + P + + + K + +K K T
Sbjct: 1163 KDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVT 1222
Query: 276 GKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEE------KPSGHKLSFCDS 329
G + ++ +S S+ S E D + T EE P+ +
Sbjct: 1223 GTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQV 1282
Query: 330 PGQMMKNSVDSVKNSTVAIKS-RPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSE 388
P K D ++ +KS +P+S V S K++ + +N+ K+ SE
Sbjct: 1283 P--QSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE------SE 1334
Query: 389 PVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKL 448
P + Q+ TK + + + VKSS +S S++ K
Sbjct: 1335 PSEKI--------------QKFTKDVSHEIIQ---------HEVKSSKNSASSEKGKTKD 1371
Query: 449 DHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQV 508
+ EK+ P+++ KN Q +K L+ + + +
Sbjct: 1372 RDYSVLEKENPEKR--------------------KNSTQPEKESNLDRLNEQGNF---KS 1408
Query: 509 ISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQS 568
+S++ ++ KH+++ R ++NKD + D S
Sbjct: 1409 LSQSSKEARTSDKHDST----------RASSNKDFTPNRDKKTDY--------DTREYSS 1450
Query: 569 SCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCD 628
S R D + L + K S + S Q + E P K T D
Sbjct: 1451 SKRRDEKNELTRR-------------KDSPSRNKDSASGQKNKPREERDLPK-KGTGDSK 1496
Query: 629 AANICCHSVGSDNVNSKFYSTTALKYMVSNPNE--NSLNSNPVCDLDSTSAGQIHLISDR 686
+N S + + K + A Y PNE S++ NP DR
Sbjct: 1497 KSN------SSPSRDRKPHDHKA-TYDTKRPNEETKSVDKNP--------------CKDR 1535
Query: 687 ENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLN--SAQEDKKSKVPVEGLTIPSKLS-- 742
E V NK+SS + + + NP T + Q DK + P L+ S+LS
Sbjct: 1536 EKHVLEARNNKESSGNKL--LYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSD 1593
Query: 743 -----DESAMDED-KHATADSDVSSKCFSGQLSEKNSPKNMETSESPESHETPETPFVGH 796
DE+A + D + ++S+VS K + S N K+++ ++ E+ +T V
Sbjct: 1594 LTRETDEAAFEPDYNESDSESNVSVK---EEESSGNISKDLKDKIVEKAKESLDTAAVVQ 1650
Query: 797 WNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCH 856
+S +Q S S + S + S + RS A ++ D + + H
Sbjct: 1651 VGISR---NQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKH 1707
Query: 857 DFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDE 903
+ T EL + + + + K KK N + DD+
Sbjct: 1708 KKHKKHKKHAGTEVEL---EKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 42.4 bits (98), Expect = 0.003
Identities = 168/827 (20%), Positives = 292/827 (35%), Gaps = 177/827 (21%)
Query: 136 STNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASK--ITKELKTGGKNVS 193
S+ K K G HS S + K +K++ VK+ + S+ TKE K N
Sbjct: 1077 SSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEK 1136
Query: 194 GKP------KTVTKSKTENGDK---------ARLE-----NMSPRQVVE----------- 222
KP K K++ + DK ++LE SP++ +E
Sbjct: 1137 NKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPE 1196
Query: 223 --RSATAAAAATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLK-----KAT 275
+ + +A A + N GK + + E + P + + + K + +K K T
Sbjct: 1197 KDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVT 1256
Query: 276 GKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEE------KPSGHKLSFCDS 329
G + ++ +S S+ S E D + T EE P+ +
Sbjct: 1257 GTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQV 1316
Query: 330 PGQMMKNSVDSVKNSTVAIKS-RPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSE 388
P K D ++ +KS +P+S V S K++ + +N+ K+ SE
Sbjct: 1317 P--QSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE------SE 1368
Query: 389 PVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKL 448
P + Q+ TK + + + VKSS +S S++ K
Sbjct: 1369 PSEKI--------------QKFTKDVSHEIIQ---------HEVKSSKNSASSEKGKTKD 1405
Query: 449 DHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQV 508
+ EK+ P+++ KN Q +K L+ + + +
Sbjct: 1406 RDYSVLEKENPEKR--------------------KNSTQPEKESNLDRLNEQGNF---KS 1442
Query: 509 ISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQS 568
+S++ ++ KH+++ R ++NKD + D S
Sbjct: 1443 LSQSSKEARTSDKHDST----------RASSNKDFTPNRDKKTDY--------DTREYSS 1484
Query: 569 SCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCD 628
S R D + L + K S + S Q + E P K T D
Sbjct: 1485 SKRRDEKNELTRR-------------KDSPSRNKDSASGQKNKPREERDLPK-KGTGDSK 1530
Query: 629 AANICCHSVGSDNVNSKFYSTTALKYMVSNPNE--NSLNSNPVCDLDSTSAGQIHLISDR 686
+N S + + K + A Y PNE S++ NP DR
Sbjct: 1531 KSN------SSPSRDRKPHDHKA-TYDTKRPNEETKSVDKNP--------------CKDR 1569
Query: 687 ENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLN--SAQEDKKSKVPVEGLTIPSKLS-- 742
E V NK+SS + + + NP T + Q DK + P L+ S+LS
Sbjct: 1570 EKHVLEARNNKESSGNKL--LYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSD 1627
Query: 743 -----DESAMDED-KHATADSDVSSKCFSGQLSEKNSPKNMETSESPESHETPETPFVGH 796
DE+A + D + ++S+VS K + S N K+++ ++ E+ +T V
Sbjct: 1628 LTRETDEAAFEPDYNESDSESNVSVK---EEESSGNISKDLKDKIVEKAKESLDTAAVVQ 1684
Query: 797 WNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCH 856
+S +Q S S + S + S + RS A ++ D + + H
Sbjct: 1685 VGISR---NQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKH 1741
Query: 857 DFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDE 903
+ T EL + + + + K KK N + DD+
Sbjct: 1742 KKHKKHKKHAGTEVEL---EKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1785
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 42.0 bits (97), Expect = 0.004
Identities = 66/304 (21%), Positives = 122/304 (40%), Gaps = 47/304 (15%)
Query: 297 EFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRV 356
E STE ++ + +T KP+ D P K ++D K+ST ++ P S
Sbjct: 135 ELPKSTEIHEQKRHCNTTRHSKPT-------DKPTGNSK-TIDH-KSSTDNHEAPPTSEE 185
Query: 357 TNGTSNKKSIHEQDTNVN----NSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTK 412
+ K + +V+ + K+ +GK P P++ + R ++ G + +++
Sbjct: 186 NSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSD 245
Query: 413 STPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALP 472
T L K+ + K+S SS H TTT KQ T+ P
Sbjct: 246 KTGRPLEKSMSTLD------KTSTSS-----------HKTTTSFHNSGNSQTKQKSTSFP 288
Query: 473 KVNAKIVAMPKNLNQS--KKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHE--TSTVQ 528
+ KI A K ++ E+ +DS+ + ++++KT + Q + T ++
Sbjct: 289 E---KITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLA 345
Query: 529 KSMFHDVRDNNNKDSVSEQKPHKPLINLASE---ISDAEALQSSCR-------PDPQKPL 578
+ H R N ++ S +P + A+E +S AE ++ R P P P
Sbjct: 346 EPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPT 405
Query: 579 NDQE 582
++E
Sbjct: 406 ENRE 409
Score = 37.4 bits (85), Expect = 0.099
Identities = 99/533 (18%), Positives = 179/533 (33%), Gaps = 92/533 (17%)
Query: 186 KTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKN-LLNGKGVR 244
+T +N + P TE+G++ EN +P + A G++ N K
Sbjct: 429 RTANENTTPSPA----EPTEHGERTANENTTP-------SPAEPTEHGERTPFANDKTTS 477
Query: 245 NQEGQISGARPKVLTGNLNVQAKAKPL--KKATGKDSPCLSIAGPS-SRSTDSSMEFSIS 301
+ L + A+P ++ T ++ S AGP+ +R T ++ + ++S
Sbjct: 478 SSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLS 537
Query: 302 TECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDS--VKNSTVAIKSRPVS---RV 356
E +E + E+ PS P + +N + T + + P R
Sbjct: 538 PVEPTENRETTANEKTTPS---------PAEPTENGQRTPFANEKTTSSSAEPTEHGERT 588
Query: 357 TNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPS 416
N + T + + +EP T NG K+TPS
Sbjct: 589 PLANENTTPSPAEPTENRERTANEKTTPSPAEP----------TENGDRTPLANEKTTPS 638
Query: 417 NLTKTQGSQG---ESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAP---KRKMVKQVHTA 470
T+ Q + + SS + +E + NTT P + + + T
Sbjct: 639 LAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTP 698
Query: 471 LP---------KVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQ-------VISKTQP 514
P N K P ++++ T N K + P + KT
Sbjct: 699 SPAGPTENREMTANEKTTLFPAEPTENRE-RTANEKTTSSPAEPTENGQRTPFANEKTTS 757
Query: 515 SSQRPLKHETSTV---QKSMFHDVRDNNNKDSVSEQK----PHKPLINLASEISDAEALQ 567
SS P +H T + + N++ + +K P +P N ++
Sbjct: 758 SSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANE----- 812
Query: 568 SSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDC 627
+ P P +P + ++ LA E K SL E+ + T F N K T
Sbjct: 813 -NTTPSPAQPTENGDRTPLANE-----KTTPSLAEPTENGK------RTPFANEKTTS-- 858
Query: 628 DAANICCHS----VGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDLDSTS 676
+A H+ + ++N S T + +N + P + +ST+
Sbjct: 859 SSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA 911
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.122 0.337
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,280,435
Number of Sequences: 37866
Number of extensions: 2375724
Number of successful extensions: 9089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 335
Number of HSP's that attempted gapping in prelim test: 8088
Number of HSP's gapped (non-prelim): 1118
length of query: 1354
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1240
effective length of database: 13,930,794
effective search space: 17274184560
effective search space used: 17274184560
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.