Guide to the Human Genome
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Search of human proteins with 194578898

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
         (379 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]         813   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    88   1e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    84   3e-16
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             77   3e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    74   2e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    74   2e-13
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          74   3e-13
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          74   3e-13
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          74   3e-13
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    70   2e-12
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       70   3e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     70   4e-12
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    67   2e-11
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    67   3e-11
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    66   5e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    64   2e-10
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    64   2e-10
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    64   2e-10
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    64   2e-10
gi|112421108 capicua homolog [Homo sapiens]                            63   4e-10
gi|18959210 WIRE protein [Homo sapiens]                                63   4e-10
gi|11386183 WAS protein family, member 2 [Homo sapiens]                62   7e-10
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    62   1e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     61   1e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     61   1e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   61   1e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   61   1e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   61   1e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    61   1e-09
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       61   1e-09

>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
          Length = 379

 Score =  813 bits (2099), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 1   METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGP 60
           METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGP
Sbjct: 1   METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGP 60

Query: 61  GELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEE 120
           GELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEE
Sbjct: 61  GELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEE 120

Query: 121 EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSS 180
           EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSS
Sbjct: 121 EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSS 180

Query: 181 RPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL 240
           RPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL
Sbjct: 181 RPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL 240

Query: 241 RQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQP 300
           RQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQP
Sbjct: 241 RQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQP 300

Query: 301 RRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGG 360
           RRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGG
Sbjct: 301 RRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGG 360

Query: 361 PAVPEPPGLKFWGINMDES 379
           PAVPEPPGLKFWGINMDES
Sbjct: 361 PAVPEPPGLKFWGINMDES 379


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 109/385 (28%), Positives = 136/385 (35%), Gaps = 38/385 (9%)

Query: 6    PAPRLAVPASPRGSPCSPTPR---KPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGE 62
            P P  A P SP+G P +P+P+    P   T   SP    A      A    +   P P  
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPAATPP-SPKGGPATPSPKGAPTPPAVTPPSPKG 1021

Query: 63   LAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEG 122
              A +P  +G   P      +P G     +P   P +P  A    A     P+ G     
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKG-----SPAATP-LPKGAPTTPAATLPSPKGGPATPS 1075

Query: 123  GGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLE--PQRG----PAASPPQ 176
              G P     +   P   PA P P+ +    A+ PP P  GL   P +G    PAA+PP 
Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135

Query: 177  EPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASP--AP 234
                    PP G  T PA    +P+  L   P +     P A P +P    +T SP  AP
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195

Query: 235  AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKG----PARGAAKKRRL 290
              P          L   S         A   PS + G   P  KG    PA      +  
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254

Query: 291  PAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCP-------PALVVGEDGDLKPASSLRLQG 343
            PA PP    P  PA T P     SL      P       PA+V        PA+S   +G
Sbjct: 1255 PATPPPKGAPTPPAATPP-----SLKGGLATPPHKGAPNPAVVTPPSPKGGPATS-PPKG 1308

Query: 344  DSKPPPAHPLWRWQMGGPAVPEPPG 368
               PP A P      G P  P P G
Sbjct: 1309 APTPPAATP--PSPKGSPGTPPPKG 1331



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 108/399 (27%), Positives = 137/399 (34%), Gaps = 105/399 (26%)

Query: 6    PAPR--LAVPASPRGSPCSP--TPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPG 61
            P+P+  LA P  P+G+P +P  TP  P  G     P         A   P A+   P  G
Sbjct: 1134 PSPKGGLATPP-PKGAPTTPAATPPSPKGGLATPPPKG-------APTTPAATPPSP-KG 1184

Query: 62   ELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEE 121
             LA  SP      AP  P    P     L  P+ + G P T A         P+ G    
Sbjct: 1185 GLATPSP----KGAPTTPAATPPSPKGGLATPSPK-GAPTTPAATPPS----PKGGLATP 1235

Query: 122  GGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGL----------------- 164
               G P     +   P   PA P P+ + T  A+ PP    GL                 
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295

Query: 165  EPQRGPAASPPQEPSSRPPSPPAGLSTEPAG-PGTAPRPFLPGQPAEVDGNPPPAAPEAP 223
             P+ GPA SPP+      P+PPA     P G PGT P    P         PP   P +P
Sbjct: 1296 SPKGGPATSPPKGA----PTPPAATPPSPKGSPGTPPPKGAP--------TPPAVTPPSP 1343

Query: 224  AASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAK----- 278
              +P+  +  P++ G                          TPS + GP  P A      
Sbjct: 1344 KGTPTLPATTPSSKG-----------------------GPTTPSSKEGPTPPAATPSHKG 1380

Query: 279  GPARGAAKKRRLPAPPPRTAQPRRPA--PTLPTTSTFSLLNCFPCPPALVVGEDGDLKPA 336
            GPA      +R PA P     P  PA  P  P  +           PA  V  +G   P+
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA-----------PATPVTREGAATPS 1429

Query: 337  SSLRLQGDSKPPPAHPL-------WRWQMGGPAVPEPPG 368
                 +GD  PP   P+            GGPA P   G
Sbjct: 1430 -----KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 94/360 (26%), Positives = 120/360 (33%), Gaps = 75/360 (20%)

Query: 11   AVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVL 70
            A P +P G+  SP          E S L   +L+F       A++  P P       P  
Sbjct: 815  AGPDTPIGNLSSPV------SPVEASFLPENSLSFQGSKDSPATTHSPTP-------PSP 861

Query: 71   RGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFG 130
            +G   P      +P G+      T  P V N    ++      P++          P   
Sbjct: 862  KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921

Query: 131  VRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLS 190
              + AP G  PA P P+ + T  A+ PP P  G  P        P  P++ PPSP  G  
Sbjct: 922  RATPAPKG-IPASPSPKGAPTPPAATPPSPKGG--PATPSPKWAPTPPAATPPSPKGG-- 976

Query: 191  TEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASP--APAAPGDLRQEHFDRL 248
              PA P     P            PP A P +P   P+T SP  AP  P           
Sbjct: 977  --PATPSPKGAP-----------TPPAATPPSPKGGPATPSPKGAPTPPAVTPPS----- 1018

Query: 249  IRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLP 308
                      KG    TP   +G   PPA  P          P P      P  PA TLP
Sbjct: 1019 ---------PKGSPAATP-FPKGASTPPAATPPSPKGSPAATPLP---KGAPTTPAATLP 1065

Query: 309  TTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPG 368
            +                   + G   P+    L+G   PP A P      GGPA P P G
Sbjct: 1066 SP------------------KGGPATPS----LKGAPTPPAATP--PSPKGGPATPSPKG 1101



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 91/377 (24%), Positives = 117/377 (31%), Gaps = 43/377 (11%)

Query: 6    PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPL-----CLRALAFCALAKPRASSLGPGP 60
            P P  A P SP+GSP +P P+          P       L A    +   P   S   GP
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369

Query: 61   GELAA----------------RSPVLRGPQA-PLRPGGWAPDGLKHLWAPTGRPGVPNTA 103
               AA                R P +  P+  P  P        K    P  R G    +
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429

Query: 104  AGEDADVAACP---RRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRP 160
             G+    A  P   ++        G P        P      PP P+E       AP + 
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP-----APKQV 1484

Query: 161  APGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAP 220
            A    P++ PA   P    + P   P+     PA P +   P  P         P   AP
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544

Query: 221  EAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAK-- 278
            +     P+   P+P     +           SK    A      TPS  +G   P     
Sbjct: 1545 KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSK---EASSPPAVTPSTYKGAPSPKELLI 1601

Query: 279  GPARGAAKKRRLPAPPPRTAQ-----PRRPAPTLPTTS---TFSLLNCFPCPPALVVGED 330
             PA  +   +  P PP  T       P  PAP    TS   T S L   P  PA V  + 
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661

Query: 331  GDLKPASSLRLQGDSKP 347
            G   P +S  L     P
Sbjct: 1662 GATVPQASKGLPAKKGP 1678



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 89/350 (25%), Positives = 121/350 (34%), Gaps = 55/350 (15%)

Query: 7    APRL--AVPASPRGSPCSPTPRK-PCRGTQEF----SPLCL---RALAFCALA--KPRAS 54
            AP L   +P+SP+  P +P+ R+ P   T       +P  L    AL   A+    P+ +
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 55   SLGPGPGELAARSPVLRGPQAP-LRPGGW--APDGLKHLWAPTGRPGVPNTAAGEDADVA 111
               P P E  A          P + P  +  AP   + L  P      P  A    A   
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621

Query: 112  ACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPA 171
              P +G       G P        P     +P  P   T    +  P+ + GL  ++GP 
Sbjct: 1622 PSPEKGPATPAPKGTPTSP--PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT 1679

Query: 172  ASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS 231
            A      +  P S P   +    GP          Q  +     PP  P+  A + S   
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGP----------QTKKSSATSPPICPDPSAKNGSKGP 1729

Query: 232  PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPP---AKGPARGAAKKR 288
             +  AP  L     D     SK    AKG   D     +GP  PP   A  P   AA ++
Sbjct: 1730 LSTVAPAPLLPVQKD----SSKT---AKG--KDASHSPKGPLAPPESKASTPLTAAAFEK 1780

Query: 289  RLP---------APPPRTAQPRRPA--PTLPTTSTFSLLNCFPCPPALVV 327
             LP         AP P  + P  P+  PTLP    F      P  P LV+
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQF-----LPSSPGLVL 1825



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 61/274 (22%), Positives = 91/274 (33%), Gaps = 54/274 (19%)

Query: 6    PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRAS-SLGPGPGELA 64
            P P    P SP   P +P P+    GT    P+   +L     +    +  +G    + +
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPK----GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQAS 1669

Query: 65   ARSPVLRGPQAP----LRPGGWAPDGLKHLWAPTGR-----------------PGVPNTA 103
               P  +GP A     + P   AP+    + APT +                 P   N +
Sbjct: 1670 KGLPAKKGPTALKEVLVAP---APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS 1726

Query: 104  AGEDADVAACPRRGEEEEG-----GGGFPHFGVRSCAPP-GRCPAP----------PHPR 147
             G  + VA  P    +++      G    H      APP  +   P          P P 
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE 1786

Query: 148  ESTTSFASAPP-------RPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAP 200
             ++ S A +PP        P P L P++    S P      P  P A    +   P   P
Sbjct: 1787 SASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPP 1846

Query: 201  RPFLPGQPAE--VDGNPPPAAPEAPAASPSTASP 232
             P   G P +  +   P P +   P  +PS   P
Sbjct: 1847 EPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 65/280 (23%), Positives = 84/280 (30%), Gaps = 54/280 (19%)

Query: 140 CPAPPHPRESTTSFAS---APPRPAPGLEPQRGPAASPP--------------QEPSSRP 182
           CP  P P+ +    A+   AP  P     P   PA +PP                 +S P
Sbjct: 708 CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP 767

Query: 183 ---PSPPAGLSTEPAGPGT----APRPFLPGQPAEVDGNPPP-----AAPEAP------A 224
              P+  +G S   +  GT    A  P   G         PP     A P+ P       
Sbjct: 768 KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827

Query: 225 ASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGF---ALDTPSLRRGPERPPAKGPA 281
            SP  AS  P      +          S      KG    +  TP   +G   PP + P 
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887

Query: 282 RGAAKKRRLPAPP--PRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSL 339
                   LP P   P T  P++      T+S+       P P  +         P    
Sbjct: 888 PSVV---NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA 944

Query: 340 RLQGDSKPPPAHPLWRW-----------QMGGPAVPEPPG 368
                 K  PA P  +W             GGPA P P G
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG 984



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 5/95 (5%)

Query: 146 PRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLP 205
           P  S  S  +A  +P P L P   PA       ++   SP    ST  + P   P P   
Sbjct: 27  PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFP--- 83

Query: 206 GQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL 240
            Q +     P   APEAP   P+   P P +P  L
Sbjct: 84  -QSSSGTALPLGTAPEAPTFLPNLIGP-PISPAAL 116


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 116/407 (28%), Positives = 145/407 (35%), Gaps = 68/407 (16%)

Query: 8   PRLAVPASPRGSPCSPTPRKPC-----RGTQEFSPLCLRA-LAFCALAKPRASSLGPGPG 61
           PR A  A PR  P +  PRK         T E SP   R   A   L +P + SL     
Sbjct: 190 PRPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247

Query: 62  ELA--ARS-PVLRG-PQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
            L+  ARS P  RG P+AP  P    P GL+ L  P   P        +DA  A  P   
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP------PRKDAAPALGPLSS 301

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQE 177
                    P   ++S APP   PA PH    T   A+  P   P       P+A P  +
Sbjct: 302 SPLATPS--PSAALQSQAPP-TLPATPHSSSLTCQLATPLPLAPPS------PSAPPSLQ 352

Query: 178 PSSRPPSPPAGLSTEPAGPGT--APRPFLPGQPAEVDGNPPPAAPEA-----------PA 224
               PP+ P   +T   G  T  A   FLP  P      PPP AP A           P 
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 225 ASP---STASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPA 281
           ASP     A+P+P AP  L                    F+            PP++ P 
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472

Query: 282 RGAAKKRRLP------------------APPPRTAQP---RRPAPTLPTTSTFSLLNCFP 320
             AA   ++P                  APPP  A P    +P P  P       L   P
Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532

Query: 321 CPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
            PPA   G+     P++SL +   + PPP  P     +  P +  PP
Sbjct: 533 SPPASFPGQ-APFSPSASLPMSPLATPPPQAPP---VLAAPLLQVPP 575



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 100/382 (26%), Positives = 125/382 (32%), Gaps = 62/382 (16%)

Query: 8   PRLAVPASPRGSPC-----SPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGE 62
           P    P SP   P      SP    P + T       L+A     L  P  S L   P +
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA-THSFLPSPPLSPLATPPPQ 395

Query: 63  LAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEG 122
                P L  P     P   A   L  L  P+  P  PN  A         P      + 
Sbjct: 396 AP---PALALPPLQAPPSPPASPPLSPLATPS--PQAPNALAVHLLQAPFSPPPSPPVQA 450

Query: 123 GGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPR-PAPGLEPQRGPAASPPQEPSSR 181
                         P   PA P    S T  + APP   AP L+    P ASPP  PS+ 
Sbjct: 451 --------------PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496

Query: 182 PP--------SPPAGLSTEP--AGPGTAPRPF--LPGQPAEVDGNPPPAAPEAPAASPST 229
           PP        +PP  L+  P  A P  A  P   LP  PA   G  P  +P A       
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP-FSPSASLPMSPL 555

Query: 230 ASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKR- 288
           A+P P AP  L                        +P+L+  P RPP  GP    +  R 
Sbjct: 556 ATPPPQAPPVLAAPLLQ-----------VPPSPPASPTLQ-APRRPPTPGPDTSVSGPRL 603

Query: 289 ---RLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDS 345
                P PPP  +  R P+ TL         +     P  + G D   +  ++     D+
Sbjct: 604 TLALAPGPPPPPS--RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 661

Query: 346 KPPPAHPLWRWQMGGPAVPEPP 367
           +    HP   W  G    P PP
Sbjct: 662 ELAACHPA-AWSRG----PAPP 678



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 69/265 (26%), Positives = 86/265 (32%), Gaps = 54/265 (20%)

Query: 7   APRLAVPASPRGSP-CSPTPRKPCRGTQEFSPLCLRALAFC--------ALAKPRASSLG 57
           AP L VP SP  SP  SP+   P    Q   PL    L           ALA P   +L 
Sbjct: 476 APPLQVPPSPPASPPMSPSATPP---PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWA------PTGRPGVPNTAAGEDADVA 111
             P     ++P       P+ P    P     + A      P   P  P   A       
Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA------- 585

Query: 112 ACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPREST---------TSFASAPPRPAP 162
             PRR              +     PG  P P     ST         +S A++ P    
Sbjct: 586 --PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643

Query: 163 GLE--PQRGPAASPPQEPS---------SRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEV 211
           G +  P+ G AASPP +           SR P+PP      P  P       LP  PA  
Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP-------LPWPPATG 696

Query: 212 DGNPPPAAPEAPAASPSTASPAPAA 236
            G+            P +A+PAP A
Sbjct: 697 PGSADGLCTIYETEGPESATPAPGA 721



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/165 (26%), Positives = 56/165 (33%), Gaps = 28/165 (16%)

Query: 162 PGLEPQRGP---AASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPA 218
           P   P+ GP   A +  + P+SRPP+   G    PA   T+P P     P    G   P 
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPA-KNTSPGPV--SSPGRASGTTRPG 127

Query: 219 -------------------APEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAK 259
                              A EAP  S  +A       G         + RRS+      
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 260 GFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPA 304
           G     PS R    RPP +GP +  +         P  A  RRP+
Sbjct: 188 GLPRPAPSAR---PRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 59/220 (26%), Positives = 72/220 (32%), Gaps = 33/220 (15%)

Query: 154 ASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDG 213
           A  P   APGL   R     PP  P   PP  PA L    A      +P           
Sbjct: 14  ARTPAARAPGLLTPR-----PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 214 NPPPAAPEA-PAASPSTAS--PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFA-------- 262
             P +AP A P  S  T+S  PA   P   R E        S     + G A        
Sbjct: 69  TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128

Query: 263 LDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQ---PRRPAPTLPTTSTFS----- 314
           L    LR   E   A+G A  A K+  L A   R      P  P+P +   S  +     
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 315 ----LLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPA 350
                 +  P PP      +G  K  SS      ++P PA
Sbjct: 189 LPRPAPSARPRPPT-----EGPRKSVSSASEHSTTEPSPA 223


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 34/64 (53%), Positives = 43/64 (67%), Gaps = 1/64 (1%)

Query: 313 FSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPP-PAHPLWRWQMGGPAVPEPPGLKF 371
           F  +  FPCPP+L++G DGDL PA SL    DS+ P  AHP+W+WQ+GG A+P PP  KF
Sbjct: 844 FHFMANFPCPPSLIIGRDGDLWPAYSLNTTKDSQTPHKAHPIWKWQLGGSAIPLPPSHKF 903

Query: 372 WGIN 375
              N
Sbjct: 904 RKFN 907


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 107/365 (29%), Positives = 129/365 (35%), Gaps = 61/365 (16%)

Query: 5   CPAP-RLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGEL 63
           CPAP  L  P SP  +P   TP        + +P  L +     L  P  S L   P + 
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQ-APPALASPPLQGLPSPPLSPLATPPPQA 621

Query: 64  ----------AARSPVLRGPQAPLR-PGGWAPDGLKH--LWAPTGRPGVPNTAAGEDADV 110
                     A  SP    P +PL  P   AP+ L    L AP   P  P   A   +  
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPP 680

Query: 111 AACPRRGEEEEGGGGFPHFGVRSCAPPGRCPA-PPHPRESTTSFASAPPRPAPGLEPQRG 169
           A+ P            P         P   PA PP    +T    + PP  AP L+    
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740

Query: 170 PAASPPQEPSSR-PPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPS 228
           P ASPP  PS+  PP  P  L+  P     +P   LP  P      PPP AP A A  P 
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL---AKPPPQAPPALATPPL 797

Query: 229 TASPAPAA--PGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGP-ERPPAKGPARGAA 285
            A P+P A  PG   Q  F                   + SL   P   PP + P   AA
Sbjct: 798 QALPSPPASFPG---QAPFS-----------------PSASLPMSPLATPPPQAPPVLAA 837

Query: 286 KKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDS 345
              ++P  PP  A P   AP  P T         P P   V G      P  +L L    
Sbjct: 838 PLLQVPPSPP--ASPTLQAPRRPPT---------PGPDTSVSG------PRLTLALAPGP 880

Query: 346 KPPPA 350
            PPP+
Sbjct: 881 PPPPS 885



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 73/274 (26%), Positives = 97/274 (35%), Gaps = 56/274 (20%)

Query: 133 SCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTE 192
           S APP   P        TT     PP PAP       P  +PP   ++ PP  P+ ++T 
Sbjct: 540 SLAPP---PLQTASAPLTTPHLETPPCPAPC------PLQAPPSPLTTPPPETPSSIATP 590

Query: 193 P--AGPGTAPRPF--LPGQPAEVDGNPPPAAP--------EAPAASPST------ASPAP 234
           P  A P  A  P   LP  P      PPP AP        +AP + P++      A+P+P
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLP--- 291
            AP  L                    F+            PP++ P   AA   ++P   
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710

Query: 292 ---------------APPPRTAQPRRPAPTLPTTSTFSLLNCFP--CPPALVVGE-DGDL 333
                          APPP  A P +  P+ P +   S     P   PP L         
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770

Query: 334 KPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
            P +SL +   +KPPP  P        PA+  PP
Sbjct: 771 SPPASLPMSPLAKPPPQAP--------PALATPP 796



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 74/257 (28%), Positives = 89/257 (34%), Gaps = 50/257 (19%)

Query: 4   LCPAPRLAVPASPRGS-PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGE 62
           L  AP L VP SP  S P SP  + P +     +P  L      AL  P AS  G  P  
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQ-----APPALATPPLQALPSPPASFPGQAPF- 813

Query: 63  LAARSPVLRGPQAPLR-PGGWAPDGLKH--LWAPTGRPGVPNTAAGEDADVAACPRRGEE 119
               SP    P +PL  P   AP  L    L  P   P  P   A         PRR   
Sbjct: 814 ----SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA---------PRRPPT 860

Query: 120 EEGGGGFPHFGVRSCAPPGRCPAPPHPREST---------TSFASAPPRPAPGLE--PQR 168
                      +     PG  P P     ST         +S A++ P    G +  P+ 
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920

Query: 169 GPAASPPQEPS---------SRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAA 219
           G AASPP +           SR P+PP      P  P       LP  PA   G+     
Sbjct: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP-------LPWPPATGPGSADGLC 973

Query: 220 PEAPAASPSTASPAPAA 236
                  P +A+PAP A
Sbjct: 974 TIYETEGPESATPAPGA 990



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 82/319 (25%), Positives = 107/319 (33%), Gaps = 56/319 (17%)

Query: 6   PAPRLAVPASPRGSP-CSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGP---GPG 61
           P+P +  P SP  SP  SP+   P +     +   L+       + P + S  P    P 
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728

Query: 62  ELAARSPVLRGPQAP-----LRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRR 116
            LAA  P L+ P +P     + P    P  +  L A       P+  A       A P  
Sbjct: 729 PLAA--PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP- 785

Query: 117 GEEEEGGGGFPHFGVRSCAP---PGRCPAPPHPRESTTSFASAPPRP-----APGLEPQR 168
             +       P        P   PG+ P  P      +  A+ PP+      AP L+   
Sbjct: 786 -PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844

Query: 169 GPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPS 228
            P ASP  +   RPP+P  G  T  +GP            A   G PPP     P+ SPS
Sbjct: 845 SPPASPTLQAPRRPPTP--GPDTSVSGPRLT--------LALAPGPPPP-----PSRSPS 889

Query: 229 TASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKR 288
           +    P   G                       A  TP   RG +  P  G A       
Sbjct: 890 STLSGPDLAGH-------------------SSSATSTPEELRGYDSGPEGGAAASPPPDA 930

Query: 289 RLPAPPPRTAQPRRPAPTL 307
            L A  P  A  R PAP L
Sbjct: 931 ELAACHP-AAWSRGPAPPL 948



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 99/368 (26%), Positives = 124/368 (33%), Gaps = 90/368 (24%)

Query: 8   PRLAVPASPRGSPCSPTPRKPC-----RGTQEFSPLCLRA-LAFCALAKPRASSLGPGPG 61
           PR A  A PR  P +  PRK         T E SP   R   A   L +P + SL     
Sbjct: 190 PRPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247

Query: 62  ELA--ARS-PVLRG-PQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
            L+  ARS P  RG P+AP  P    P GL+ L  P   P                PR+ 
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP----------------PRKD 291

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQE 177
                    P  G  S +P     A P P     S   A P P P        AA+P   
Sbjct: 292 AA-------PALGPLSSSPL----ATPSP-----SGTKARPVPPPD------NAATPL-- 327

Query: 178 PSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAP 237
           P++ PPSPP       A P  +  P L   P+     PP  AP +    P  A P+    
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTI 386

Query: 238 GDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGP--------ERPPAKGPARGAAKKRR 289
             ++  H                 +L +PSL+  P        +   + G     A    
Sbjct: 387 PPIQVPH-----------------SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429

Query: 290 LPAPPPRT----AQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDS 345
           L   P +T      P RPA T P +         P  P L       + P SS       
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS------- 482

Query: 346 KPPPAHPL 353
            P   HPL
Sbjct: 483 -PLTIHPL 489



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 101/428 (23%), Positives = 136/428 (31%), Gaps = 112/428 (26%)

Query: 3   TLCPAPRLAVPA-----SPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLG 57
           TL P+P LA P      SP   P   T   P       +P  +        A P   ++ 
Sbjct: 330 TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM--QAPPSLQTIP 387

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
           P     +  SP L+ P +PL         L  L A T   G P T     + +   PR+ 
Sbjct: 388 PIQVPHSLTSPSLQAPPSPL--------ALSSLQATTSL-GSP-TLQATHSFLTMSPRQT 437

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASP--- 174
           +            + S + P   P    P ++  S  ++PP     L P   P +SP   
Sbjct: 438 QAS----------LTSPSRPASTPPDSPPLQAPLSLPASPPLQT-SLSPAVSPLSSPLTI 486

Query: 175 -------------PQEPSSR-------------PPS---PPAGLSTEP------------ 193
                        PQ P S              PPS   PPA L+T P            
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546

Query: 194 ---AGPGTAPRPFLPGQPAEVD--------GNPPPAAPEAPAASPSTASPAPAAPGDLRQ 242
              + P T P    P  PA             PPP  P + A  P  A PA A+P  L+ 
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP-PLQ- 604

Query: 243 EHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPP--PRTAQP 300
                               L +P L      PP   P       +  P+PP  P  +  
Sbjct: 605 -------------------GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645

Query: 301 RRPAPTLPTTSTFSLLNC-FPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMG 359
             P+P  P      LL   F  PP+  V       P +S  +   + PP   P     + 
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPV--QAPFSPPASPPVSPSATPPSQAPP---SLA 700

Query: 360 GPAVPEPP 367
            P +  PP
Sbjct: 701 APPLQVPP 708



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/165 (26%), Positives = 56/165 (33%), Gaps = 28/165 (16%)

Query: 162 PGLEPQRGP---AASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPA 218
           P   P+ GP   A +  + P+SRPP+   G    PA   T+P P     P    G   P 
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPA-KNTSPGPV--SSPGRASGTTRPG 127

Query: 219 -------------------APEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAK 259
                              A EAP  S  +A       G         + RRS+      
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 260 GFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPA 304
           G     PS R    RPP +GP +  +         P  A  RRP+
Sbjct: 188 GLPRPAPSAR---PRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 59/220 (26%), Positives = 72/220 (32%), Gaps = 33/220 (15%)

Query: 154 ASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDG 213
           A  P   APGL   R     PP  P   PP  PA L    A      +P           
Sbjct: 14  ARTPAARAPGLLTPR-----PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 214 NPPPAAPEA-PAASPSTAS--PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFA-------- 262
             P +AP A P  S  T+S  PA   P   R E        S     + G A        
Sbjct: 69  TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128

Query: 263 LDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQ---PRRPAPTLPTTSTFS----- 314
           L    LR   E   A+G A  A K+  L A   R      P  P+P +   S  +     
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 315 ----LLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPA 350
                 +  P PP      +G  K  SS      ++P PA
Sbjct: 189 LPRPAPSARPRPPT-----EGPRKSVSSASEHSTTEPSPA 223


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 104/395 (26%), Positives = 131/395 (33%), Gaps = 83/395 (21%)

Query: 49  AKPRASSLGPGPGELAARSPVL--RGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGE 106
           A  R  + GP PG     SP +  R   A    G   P        PT  P    ++A E
Sbjct: 149 AGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205

Query: 107 DADVAACPRRGEEEEGGGGFPHFGVRSC---APPGRCPAPPHPRESTTSFASA-PPRPAP 162
            +     P        GGG      RS    A P   PA   P    T  A A P +P P
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 265

Query: 163 -GLEPQRGPAASPPQEPS-----------------SRPPSP--PAGLSTEPAGPGTAP-- 200
            GL+  R P  +PP++ +                 S PPSP  P  L T P+ P T P  
Sbjct: 266 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325

Query: 201 -------------RPFLPGQPAEVDGNPPPAAPEA-----------PAASP---STASPA 233
                          FLP  P      PPP AP A           P ASP     A+P+
Sbjct: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385

Query: 234 PAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLP-- 291
           P AP  L                    F+            PP++ P   AA   ++P  
Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 292 ----------------APPPRTAQP---RRPAPTLPTTSTFSLLNCFPCPPALVVGEDGD 332
                           APPP  A P    +P P  P       L   P PPA   G+   
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ-AP 504

Query: 333 LKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
             P++SL +   + PPP  P     +  P +  PP
Sbjct: 505 FSPSASLPMSPLATPPPQAPP---VLAAPLLQVPP 536



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 110/426 (25%), Positives = 145/426 (34%), Gaps = 78/426 (18%)

Query: 6   PAPR-LAVPASPRGSPCSP------TPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGP 58
           PA R L+  A+P  SP         TPR P   +Q   P  L+AL    +  PR  +  P
Sbjct: 228 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KPKGLQALRPPQVTPPRKDA-AP 285

Query: 59  GPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP--------GVPNTAAGED--- 107
             G L++       P AP  P   AP  L+ L +P   P        G P   A      
Sbjct: 286 ALGPLSSSPLATPSPSAPPSPS--APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343

Query: 108 ----ADVAACPRRGEEEEGGGGFPHFGVRSCAP------PGRCPAPPHPRESTTSFASAP 157
               + +A  P +          P        P      P   P+P  P         AP
Sbjct: 344 SPPLSPLATPPPQAPPALA---LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400

Query: 158 --PRPAPGLEPQRGPAASPPQEPSSRPPS-------------PPAGLSTEPAGPGTAPRP 202
             P P+P ++    P ASPP  PS+ PPS             PP+  ++ P  P   P P
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460

Query: 203 FLP---GQPAEVDGNPPPAAPEAPAASPSTASPAPAA--PGDLRQEHFDRLIRRSKLWCY 257
             P     P      PPP AP A A  P  A P+P A  PG         L         
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 258 AKGF-ALDTPSLR-----------RGPERPPAKGPARGAAKKR----RLPAPPPRTAQPR 301
            +    L  P L+           + P RPP  GP    +  R      P PPP  +  R
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS--R 578

Query: 302 RPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGP 361
            P+ TL         +     P  + G D   +  ++     D++    HP   W  G  
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA-AWSRG-- 635

Query: 362 AVPEPP 367
             P PP
Sbjct: 636 --PAPP 639



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 69/265 (26%), Positives = 86/265 (32%), Gaps = 54/265 (20%)

Query: 7   APRLAVPASPRGSP-CSPTPRKPCRGTQEFSPLCLRALAFC--------ALAKPRASSLG 57
           AP L VP SP  SP  SP+   P    Q   PL    L           ALA P   +L 
Sbjct: 437 APPLQVPPSPPASPPMSPSATPP---PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWA------PTGRPGVPNTAAGEDADVA 111
             P     ++P       P+ P    P     + A      P   P  P   A       
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA------- 546

Query: 112 ACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPREST---------TSFASAPPRPAP 162
             PRR              +     PG  P P     ST         +S A++ P    
Sbjct: 547 --PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604

Query: 163 GLE--PQRGPAASPPQEPS---------SRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEV 211
           G +  P+ G AASPP +           SR P+PP      P  P       LP  PA  
Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP-------LPWPPATG 657

Query: 212 DGNPPPAAPEAPAASPSTASPAPAA 236
            G+            P +A+PAP A
Sbjct: 658 PGSADGLCTIYETEGPESATPAPGA 682



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 57/243 (23%), Positives = 76/243 (31%), Gaps = 37/243 (15%)

Query: 64  AARSPVLRGPQ--APLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEE 121
           AAR+P  R P    P  PG           +P   P V   A        A  R+   E 
Sbjct: 13  AARTPAARAPGLLTPRPPG-----------SPRPPPPVTPAALRVLGAAGAVGRKPLAER 61

Query: 122 GGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSR 181
            GG      +     P   P     R S    +    R  P      GP +SP +   + 
Sbjct: 62  AGG------IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115

Query: 182 PPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLR 241
            P P        +   T  R    G+  E     P  +  +  A   T+ P P  P    
Sbjct: 116 RPGPLGQKGLRISAEETVAR----GKATEA----PKRSALSAGARRDTSGPTPGTPS--- 164

Query: 242 QEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPR 301
                 + RRS+      G     PS R    RPP +GP +  +         P  A  R
Sbjct: 165 ----PAMARRSRAAGTEVGLPRPAPSAR---PRPPTEGPRKSVSSASEHSTTEPSPAARR 217

Query: 302 RPA 304
           RP+
Sbjct: 218 RPS 220


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 93/324 (28%), Positives = 118/324 (36%), Gaps = 67/324 (20%)

Query: 63  LAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEG 122
           L A+ P L+ P   + P   AP       AP G P +P    G      A P +G     
Sbjct: 180 LQAQPPALQAPTG-VTP---APSS-----APPGTPQLPTP--GPTPSATAVPPQGS---- 224

Query: 123 GGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRP 182
                         P    AP  P+  T        + AP L PQR P+  PP  PS  P
Sbjct: 225 --------------PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHP 270

Query: 183 P-SPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL- 240
           P  P  G + +P+ P  A  P        + G  PP  P +  A P    P P  P  L 
Sbjct: 271 PLQPLTGSAGQPSAPSHAQPP--------LHGQGPP-GPHSLQAGPLLQHPGPPQPFGLP 321

Query: 241 -RQEHFDRLIRRSKLWCYAKGFALDTPSLRRG--PERPPAKGPARGAAKKRRLPAPPPRT 297
            +       +  S    Y    +L  P+ +     ++PP + P   A        PPP T
Sbjct: 322 PQASQGQAPLGTSPAAAYPH-TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 380

Query: 298 AQPRRPAPT-------LPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPA 350
             P+ PAP        L   S FS+    P PPA        LKP SSL       PP A
Sbjct: 381 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA--------LKPLSSL---STHHPPSA 429

Query: 351 HP----LWRWQMGGPAVP-EPPGL 369
           HP    L       P+ P +PPGL
Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGL 453



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 85/329 (25%), Positives = 114/329 (34%), Gaps = 42/329 (12%)

Query: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
           PAP  A P +P+     PTP       Q  SP      A  A  +P+A +  P P     
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP-----TASQAPNQPQAPT-APVPHTHIQ 247

Query: 66  RSPVLR-----GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAA----GEDADVAACPRR 116
           ++P L       P  P  P    P  L+ L    G+P  P+ A     G+        + 
Sbjct: 248 QAPALHPQRPPSPHPPPHPSPHPP--LQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 305

Query: 117 GEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASP-P 175
           G   +  G    FG+   A  G+ P    P  +    +   P     L+ Q+ P   P P
Sbjct: 306 GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 365

Query: 176 QEPSSRP---PSPPAGLSTEPAGPGTAPRPFLPG-QPAEVDGNPPPAAPEAPAASPSTAS 231
             P + P   P P   +   PA       P L G  P  ++ N PP     P +S ST  
Sbjct: 366 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 425

Query: 232 PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLP 291
           P  A P  L+     + +  S             P L +    PP   PA          
Sbjct: 426 PPSAHPPPLQLMPQSQPLPSS---------PAQPPGLTQSQNLPPP--PASHPPTGLHQV 474

Query: 292 APPPRTAQ--------PRRPAPTLPTTST 312
           AP P  AQ        P    PT P+TST
Sbjct: 475 APQPPFAQHPFVPGGPPPITPPTCPSTST 503



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 95/358 (26%), Positives = 122/358 (34%), Gaps = 80/358 (22%)

Query: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
           PA     P SP   P  P+P  P    Q  +    +  A      P      PGP  L A
Sbjct: 250 PALHPQRPPSPHPPP-HPSPHPPL---QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 305

Query: 66  RSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP---GVPNTAAGEDADVAAC-----PRRG 117
             P+L+ P  P +P G  P   +   AP G       P+T+    A  +A      PR  
Sbjct: 306 -GPLLQHPGPP-QPFGLPPQASQGQ-APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPP---HPREST-----TSFASAPPRPA-------- 161
                    PH       P  + PAP    HP   +     +  A+ PP PA        
Sbjct: 363 PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 422

Query: 162 ---------PGLE--PQRGPAASPPQEPSSR--------PPS--PPAGLSTEPAGPGTAP 200
                    P L+  PQ  P  S P +P           PP+  PP GL      P  A 
Sbjct: 423 THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 482

Query: 201 RPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKG 260
            PF+PG P      PP      P   PST++P PA PG   Q                 G
Sbjct: 483 HPFVPGGP------PPIT----PPTCPSTSTP-PAGPGTSAQPP-------------CSG 518

Query: 261 FALDTPSLRRGPERP----PAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFS 314
            A    S+  G   P      K  A   A++   P PPPR+  P       P+ ++ S
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 576


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 93/324 (28%), Positives = 118/324 (36%), Gaps = 67/324 (20%)

Query: 63   LAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEG 122
            L A+ P L+ P   + P   AP       AP G P +P    G      A P +G     
Sbjct: 734  LQAQPPALQAPTG-VTP---APSS-----APPGTPQLPTP--GPTPSATAVPPQGS---- 778

Query: 123  GGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRP 182
                          P    AP  P+  T        + AP L PQR P+  PP  PS  P
Sbjct: 779  --------------PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHP 824

Query: 183  P-SPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL- 240
            P  P  G + +P+ P  A  P        + G  PP  P +  A P    P P  P  L 
Sbjct: 825  PLQPLTGSAGQPSAPSHAQPP--------LHGQGPP-GPHSLQAGPLLQHPGPPQPFGLP 875

Query: 241  -RQEHFDRLIRRSKLWCYAKGFALDTPSLRRG--PERPPAKGPARGAAKKRRLPAPPPRT 297
             +       +  S    Y    +L  P+ +     ++PP + P   A        PPP T
Sbjct: 876  PQASQGQAPLGTSPAAAYPH-TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934

Query: 298  AQPRRPAPT-------LPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPA 350
              P+ PAP        L   S FS+    P PPA        LKP SSL       PP A
Sbjct: 935  PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA--------LKPLSSL---STHHPPSA 983

Query: 351  HP----LWRWQMGGPAVP-EPPGL 369
            HP    L       P+ P +PPGL
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGL 1007



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 85/329 (25%), Positives = 114/329 (34%), Gaps = 42/329 (12%)

Query: 6    PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
            PAP  A P +P+     PTP       Q  SP      A  A  +P+A +  P P     
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP-----TASQAPNQPQAPT-APVPHTHIQ 801

Query: 66   RSPVLR-----GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAA----GEDADVAACPRR 116
            ++P L       P  P  P    P  L+ L    G+P  P+ A     G+        + 
Sbjct: 802  QAPALHPQRPPSPHPPPHPSPHPP--LQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 859

Query: 117  GEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASP-P 175
            G   +  G    FG+   A  G+ P    P  +    +   P     L+ Q+ P   P P
Sbjct: 860  GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919

Query: 176  QEPSSRP---PSPPAGLSTEPAGPGTAPRPFLPG-QPAEVDGNPPPAAPEAPAASPSTAS 231
              P + P   P P   +   PA       P L G  P  ++ N PP     P +S ST  
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 979

Query: 232  PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLP 291
            P  A P  L+     + +  S             P L +    PP   PA          
Sbjct: 980  PPSAHPPPLQLMPQSQPLPSS---------PAQPPGLTQSQNLPPP--PASHPPTGLHQV 1028

Query: 292  APPPRTAQ--------PRRPAPTLPTTST 312
            AP P  AQ        P    PT P+TST
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTST 1057



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 95/358 (26%), Positives = 122/358 (34%), Gaps = 80/358 (22%)

Query: 6    PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
            PA     P SP   P  P+P  P    Q  +    +  A      P      PGP  L A
Sbjct: 804  PALHPQRPPSPHPPP-HPSPHPPL---QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 859

Query: 66   RSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP---GVPNTAAGEDADVAAC-----PRRG 117
              P+L+ P  P +P G  P   +   AP G       P+T+    A  +A      PR  
Sbjct: 860  -GPLLQHPGPP-QPFGLPPQASQGQ-APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 916

Query: 118  EEEEGGGGFPHFGVRSCAPPGRCPAPP---HPREST-----TSFASAPPRPA-------- 161
                     PH       P  + PAP    HP   +     +  A+ PP PA        
Sbjct: 917  PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976

Query: 162  ---------PGLE--PQRGPAASPPQEPSSR--------PPS--PPAGLSTEPAGPGTAP 200
                     P L+  PQ  P  S P +P           PP+  PP GL      P  A 
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036

Query: 201  RPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKG 260
             PF+PG P      PP      P   PST++P PA PG   Q                 G
Sbjct: 1037 HPFVPGGP------PPIT----PPTCPSTSTP-PAGPGTSAQPP-------------CSG 1072

Query: 261  FALDTPSLRRGPERP----PAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFS 314
             A    S+  G   P      K  A   A++   P PPPR+  P       P+ ++ S
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1130


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 93/324 (28%), Positives = 118/324 (36%), Gaps = 67/324 (20%)

Query: 63   LAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEG 122
            L A+ P L+ P   + P   AP       AP G P +P    G      A P +G     
Sbjct: 734  LQAQPPALQAPTG-VTP---APSS-----APPGTPQLPTP--GPTPSATAVPPQGS---- 778

Query: 123  GGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRP 182
                          P    AP  P+  T        + AP L PQR P+  PP  PS  P
Sbjct: 779  --------------PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHP 824

Query: 183  P-SPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL- 240
            P  P  G + +P+ P  A  P        + G  PP  P +  A P    P P  P  L 
Sbjct: 825  PLQPLTGSAGQPSAPSHAQPP--------LHGQGPP-GPHSLQAGPLLQHPGPPQPFGLP 875

Query: 241  -RQEHFDRLIRRSKLWCYAKGFALDTPSLRRG--PERPPAKGPARGAAKKRRLPAPPPRT 297
             +       +  S    Y    +L  P+ +     ++PP + P   A        PPP T
Sbjct: 876  PQASQGQAPLGTSPAAAYPH-TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934

Query: 298  AQPRRPAPT-------LPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPA 350
              P+ PAP        L   S FS+    P PPA        LKP SSL       PP A
Sbjct: 935  PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA--------LKPLSSL---STHHPPSA 983

Query: 351  HP----LWRWQMGGPAVP-EPPGL 369
            HP    L       P+ P +PPGL
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGL 1007



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 85/329 (25%), Positives = 114/329 (34%), Gaps = 42/329 (12%)

Query: 6    PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
            PAP  A P +P+     PTP       Q  SP      A  A  +P+A +  P P     
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPPQG-SP-----TASQAPNQPQAPT-APVPHTHIQ 801

Query: 66   RSPVLR-----GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAA----GEDADVAACPRR 116
            ++P L       P  P  P    P  L+ L    G+P  P+ A     G+        + 
Sbjct: 802  QAPALHPQRPPSPHPPPHPSPHPP--LQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 859

Query: 117  GEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASP-P 175
            G   +  G    FG+   A  G+ P    P  +    +   P     L+ Q+ P   P P
Sbjct: 860  GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919

Query: 176  QEPSSRP---PSPPAGLSTEPAGPGTAPRPFLPG-QPAEVDGNPPPAAPEAPAASPSTAS 231
              P + P   P P   +   PA       P L G  P  ++ N PP     P +S ST  
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 979

Query: 232  PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLP 291
            P  A P  L+     + +  S             P L +    PP   PA          
Sbjct: 980  PPSAHPPPLQLMPQSQPLPSS---------PAQPPGLTQSQNLPPP--PASHPPTGLHQV 1028

Query: 292  APPPRTAQ--------PRRPAPTLPTTST 312
            AP P  AQ        P    PT P+TST
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTST 1057



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 95/358 (26%), Positives = 122/358 (34%), Gaps = 80/358 (22%)

Query: 6    PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
            PA     P SP   P  P+P  P    Q  +    +  A      P      PGP  L A
Sbjct: 804  PALHPQRPPSPHPPP-HPSPHPPL---QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA 859

Query: 66   RSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP---GVPNTAAGEDADVAAC-----PRRG 117
              P+L+ P  P +P G  P   +   AP G       P+T+    A  +A      PR  
Sbjct: 860  -GPLLQHPGPP-QPFGLPPQASQGQ-APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 916

Query: 118  EEEEGGGGFPHFGVRSCAPPGRCPAPP---HPREST-----TSFASAPPRPA-------- 161
                     PH       P  + PAP    HP   +     +  A+ PP PA        
Sbjct: 917  PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976

Query: 162  ---------PGLE--PQRGPAASPPQEPSSR--------PPS--PPAGLSTEPAGPGTAP 200
                     P L+  PQ  P  S P +P           PP+  PP GL      P  A 
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036

Query: 201  RPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKG 260
             PF+PG P      PP      P   PST++P PA PG   Q                 G
Sbjct: 1037 HPFVPGGP------PPIT----PPTCPSTSTP-PAGPGTSAQPP-------------CSG 1072

Query: 261  FALDTPSLRRGPERP----PAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFS 314
             A    S+  G   P      K  A   A++   P PPPR+  P       P+ ++ S
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1130


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 80/278 (28%), Positives = 93/278 (33%), Gaps = 49/278 (17%)

Query: 58  PGPGELAARSPVLRG-----PQAPLRPGGWAPDGLKHLWAPTGRPGVPN--TAAGEDADV 110
           P PG+   R P         P  P +P G  P G      P  RPG P      G +   
Sbjct: 52  PPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQ 111

Query: 111 AACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPH--PRESTTSFASAPPRPAP--GLEP 166
              PR G+ E   G  P  G +S  PP R P  P   P +        PPRP    G  P
Sbjct: 112 GPPPRPGKPE---GPPPQGGNQSQGPPPR-PGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 167

Query: 167 QRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNP---PPAAPEAP 223
           Q G  +  P     +P  PP     +  GP   PRP  P  P    GN    PP  P  P
Sbjct: 168 QGGNQSQGPPPHPGKPEGPPPQGGNQSQGP--PPRPGKPEGPPPQGGNQSQGPPPRPGKP 225

Query: 224 AASPSTASPAPAAP--------GDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERP 275
              PS     P  P        G   QE                G     P     P+ P
Sbjct: 226 EGPPSQGGNKPQGPPPHPGKPQGPPPQE----------------GNKPQRPPPPGRPQGP 269

Query: 276 PAKG-----PARGAAKKRRLPAPPPRTAQPRRPAPTLP 308
           P  G     P    A K + P PPP+  +P RP    P
Sbjct: 270 PPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 70/236 (29%), Positives = 81/236 (34%), Gaps = 28/236 (11%)

Query: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
           P PR   P  P G P       P  G Q   P            +    S GP P     
Sbjct: 92  PPPR---PGKPEGQP-------PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 141

Query: 66  RSPVLRG-------PQAPLRPGGWAPDGLKHLWAPTGRPGVPN--TAAGEDADVAACPRR 116
             P  +G       P  P +P G  P G      P   PG P      G +      PR 
Sbjct: 142 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP 201

Query: 117 GEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQ 176
           G+ E   G  P  G +S  PP R   P  P     +    PP P PG +PQ GP   PPQ
Sbjct: 202 GKPE---GPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPP-PHPG-KPQ-GP---PPQ 252

Query: 177 EPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASP 232
           E +     PP G    P  PG  P+  LP    +  G PPP     P   P    P
Sbjct: 253 EGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 68/251 (27%), Positives = 83/251 (33%), Gaps = 47/251 (18%)

Query: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
           P PR   P  P G P       P  G Q   P            +P      P  G   +
Sbjct: 71  PPPR---PGKPEGPP-------PQGGNQSQGPP----------PRPGKPEGQPPQGGNQS 110

Query: 66  RSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPN--TAAGEDADVAACPRRGEEEEGG 123
           + P    P  P +P G  P G      P  RPG P      G +      PR G+ E   
Sbjct: 111 QGP----PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE--- 163

Query: 124 GGFPHFGVRSCAPPGRCPAPPH--PRESTTSFASAPPRPAP--GLEPQRGPAASPPQEPS 179
           G  P  G +S  PP   P  P   P +        PPRP    G  PQ G  +  P    
Sbjct: 164 GPPPQGGNQSQGPPPH-PGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP 222

Query: 180 SRPPSPPAGLSTEPAGPGTAP------------RPFLPGQPAEVDGNPPPAA-PEAPAAS 226
            +P  PP+    +P GP   P            +P  P  P    G PPP   P+ P   
Sbjct: 223 GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPP 282

Query: 227 PSTASPAPAAP 237
           P+     P  P
Sbjct: 283 PAGKPQGPPPP 293



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 69/253 (27%), Positives = 79/253 (31%), Gaps = 76/253 (30%)

Query: 127 PHFGVRSCAPPGRCPAPPH--PRESTTSFASAPPRPAP--GLEPQRGPAASPPQEPSSRP 182
           P  G +S  PP R P  P   P +        PPRP    G  PQ G  +  P     +P
Sbjct: 62  PQGGNQSQGPPPR-PGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP 120

Query: 183 PSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGN------PPPAAPEAPAASPSTASPAPAA 236
             PP     +  GP   PRP  P  P    GN      P P  PE P       S  P  
Sbjct: 121 EGPPPQGGNQSQGP--PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 178

Query: 237 -PGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPP 295
            PG                                 PE PP +G  +          PPP
Sbjct: 179 HPGK--------------------------------PEGPPPQGGNQSQG-------PPP 199

Query: 296 RTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKP--PPAHPL 353
           R  +P  P P     S          PP      +G   P S    QG +KP  PP HP 
Sbjct: 200 RPGKPEGPPPQGGNQS--------QGPPPRPGKPEG---PPS----QGGNKPQGPPPHP- 243

Query: 354 WRWQMGGPAVPEP 366
                G P  P P
Sbjct: 244 -----GKPQGPPP 251



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 60/228 (26%), Positives = 70/228 (30%), Gaps = 68/228 (29%)

Query: 147 RESTTSFASAPP---RPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPF 203
           +E + S  S  P   RP  G +PQR P   PP +P  RPP        +  GP   PRP 
Sbjct: 25  QEESPSVISGKPEGRRPQGGNQPQRTPP--PPGKPEGRPPQG----GNQSQGP--PPRPG 76

Query: 204 LPGQPAEVDGNP---PPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKG 260
            P  P    GN    PP  P  P   P         P                       
Sbjct: 77  KPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGP----------------------- 113

Query: 261 FALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFP 320
                P     PE PP +G  +          PPPR  +P  P P     S         
Sbjct: 114 -----PPRPGKPEGPPPQGGNQSQG-------PPPRPGKPEGPPPQGGNQSQ-------- 153

Query: 321 CPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPG 368
             P    G+     P    + QG    PP HP      G P  P P G
Sbjct: 154 -GPPPRPGKPEGPPPQGGNQSQG----PPPHP------GKPEGPPPQG 190



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 45/158 (28%), Positives = 51/158 (32%), Gaps = 36/158 (22%)

Query: 55  SLGPGPGELAARSPVLRG-------PQAPLRPGGWAPDGLKHLWAPTGRPGVPN--TAAG 105
           S GP P       P  +G       P  P +P G  P G      P  RPG P      G
Sbjct: 152 SQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 211

Query: 106 EDADVAACPRRGEEE----EGG----GGFPHFGV------------RSCAPPGRCPAPP- 144
            +      PR G+ E    +GG    G  PH G             +   PPGR   PP 
Sbjct: 212 GNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPP 271

Query: 145 ------HPRESTTSFASAPPRPAPGLEPQRGPAASPPQ 176
                  P          PP P  G  P R P   PPQ
Sbjct: 272 PGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ 309


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 65/213 (30%), Positives = 86/213 (40%), Gaps = 32/213 (15%)

Query: 51  PRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP-----GVPNTAAG 105
           P+     PGPG      P  +GP    RP       L  L  P G P       P +A  
Sbjct: 463 PQGGPPQPGPG------PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQ 516

Query: 106 EDADVAACPRRGEEEE-----GGGGFPHFGVRSCAP-PGRCPAPPHPRESTTSFASAPPR 159
           + A  AA P +G+  +     GG G P       +P P R   PP     T+    APP+
Sbjct: 517 QPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK 576

Query: 160 PA---PGLEPQRGPAASPP------QEPSSRPPSPPAGLST----EPAGPGTA--PRPFL 204
            +   PG + ++GP   PP      ++ S   P P  G  T     P+GPG A  P+P L
Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQL 636

Query: 205 PGQPAEVDGNPPPAAPEAPAASPSTASPAPAAP 237
             +P++    P  AA   P      ASPA A P
Sbjct: 637 AQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 60/211 (28%), Positives = 80/211 (37%), Gaps = 18/211 (8%)

Query: 112 ACPRRGEEEEGGGGFPHFGVRS--CAPPGRC----PAPPHPRESTTSFASAPPRPAPGLE 165
           A PR+ + +   G   H    S    P GR     PA P P +        PP+P PG +
Sbjct: 417 ALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGP-PAQQRPPPQGGPPQPGPGPQ 475

Query: 166 PQRGPAASPPQEPSSRPPS---PPAGLSTEPAGPGTAPRPFLPGQPAE--VDGNPPPAAP 220
            Q  P    P     +  S   PPAG       P     P  P   A     G    + P
Sbjct: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535

Query: 221 EAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTP---SLRRG-PERPP 276
            A       A+  PA+P   RQ    +  R++ +   A   A   P     R+G P++PP
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595

Query: 277 A-KGPARGAAKKRRLP-APPPRTAQPRRPAP 305
              GP R A++   +P   PP T QPR   P
Sbjct: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPSGP 626



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 56/216 (25%), Positives = 67/216 (31%), Gaps = 40/216 (18%)

Query: 49  AKPRASSLG--PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGE 106
           A P   S G  P PG L       + P  P  P    P        P G P  P      
Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGP--PAQQRPP-------PQGGPPQPGPGPQR 476

Query: 107 DADVAAC--PRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPP------ 158
                    P +G++   G G P         P R P+P    +   S A+ P       
Sbjct: 477 QGPPLQQRPPPQGQQHLSGLGPP----AGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQ 532

Query: 159 -RPAPGLEPQRGPAASPPQEPSSR---------------PPSPPAGLSTEPAGPGTAPRP 202
            RP  G  P   PAA PP  PS +                P+PP      P G      P
Sbjct: 533 SRPVAG-GPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP 591

Query: 203 FLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPG 238
             P  PA        A P      P+T  P P+ PG
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPG 627



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 36/151 (23%), Positives = 44/151 (29%), Gaps = 22/151 (14%)

Query: 12  VPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLR 71
           V   P   P +  P  P    Q   P   R  +    A P+AS   PG  +         
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595

Query: 72  GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGV 131
           GP  P R    A         P  R G P T           PR       G   P    
Sbjct: 596 GPAGPTRQASQA--------GPVPRTGPPTTQQ---------PRPSGPGPAGRPKPQLAQ 638

Query: 132 R---SCAPPGRCPA--PPHPRESTTSFASAP 157
           +      PP    A  PPHP+   +   + P
Sbjct: 639 KPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669



 Score = 29.3 bits (64), Expect = 6.1
 Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 14/63 (22%)

Query: 176 QEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPA 235
           Q P   PP P A       GPGTA      G               APAASP+  SP  +
Sbjct: 26  QRPQPPPPPPGAHSPGATPGPGTATAERSSG--------------VAPAASPAAPSPGSS 71

Query: 236 APG 238
             G
Sbjct: 72  GGG 74


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 84/357 (23%), Positives = 111/357 (31%), Gaps = 65/357 (18%)

Query: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
           P P+     SPR  P  P    P  G Q   P             P       GP     
Sbjct: 101 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-------------PPPPGKPQGPPPQGG 147

Query: 66  RSPVLRGPQAPLRPGGWAPDG---LKHLWAPTGRPGVPNTAAGEDADVAACPR---RGEE 119
             P  +GP  P +P G  P G    +   +P G+P  P    G        P    +G  
Sbjct: 148 NKP--QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 205

Query: 120 EEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPS 179
            +GG        +   PPG+   PP   ++ +  A +PP    G  PQ G     P  P 
Sbjct: 206 PQGGNK-----PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPP 260

Query: 180 SRPPSPPAGLSTEPAGPGTAPRPFLP---GQPAEVDGNPPPAAPEAPAASPSTASPAPAA 236
            +P  PP     +P GP    +P  P   G         PP  P+ P          P  
Sbjct: 261 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPP 320

Query: 237 PGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKG-----PARGAAKKRRLP 291
           P    Q                       P     P+ PP  G     P +G +K R   
Sbjct: 321 PPGKPQG--------------------PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360

Query: 292 APPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPP 348
           +PP +   P +     P           P PPA    +     PA   + QG  +PP
Sbjct: 361 SPPGKPQGPPQQEGNNPQG---------PPPPAGGNPQQPQAPPAG--QPQGPPRPP 406



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 95/366 (25%), Positives = 124/366 (33%), Gaps = 58/366 (15%)

Query: 38  LCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP 97
           + L  L+   LA   A +L     +  + S +   PQ     GG  P G     +P G+P
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPP---SPPGKP 57

Query: 98  GVPNTAAGEDADVAACPR---RGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFA 154
             P    G        P    +G   +GG        +   PPG+   PP   + + S  
Sbjct: 58  QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-----PQGPPPPGKPQGPPPQGDKSRSPR 112

Query: 155 SAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGP-------GTAPR------ 201
           S P +P  G  PQ G     P  P  +P  PP     +P GP       G  P+      
Sbjct: 113 SPPGKPQ-GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171

Query: 202 -----PFLPGQPAEVDGN------PPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIR 250
                P  P  P    GN      PPP  P+ P          P  PG   Q    +   
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGDN 230

Query: 251 RSKLWCYAKGFALDTP----SLRRGPERPPAK--GPARGAAKKRRLPAPPPRTAQPRRPA 304
           +S+      G     P    +  +GP  PP K  GP      K   P  PP   +P+ P 
Sbjct: 231 KSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK---PQGPPPPGKPQGPP 287

Query: 305 PTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGG--PA 362
           P   + S  S       PP    G+     P    + QG   PPP  P      GG  P 
Sbjct: 288 PQGGSKSRSS-----RSPP----GKPQGPPPQGGNQPQG-PPPPPGKPQGPPPQGGNKPQ 337

Query: 363 VPEPPG 368
            P PPG
Sbjct: 338 GPPPPG 343



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 54/206 (26%), Positives = 73/206 (35%), Gaps = 36/206 (17%)

Query: 15  SPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQ 74
           SP G P  P P+    G Q   P             P       GP       P  +GP 
Sbjct: 237 SPPGKPQGPPPQG---GNQPQGP-------------PPPPGKPQGPPPQGGNKP--QGPP 278

Query: 75  APLRPGGWAPDG---LKHLWAPTGRPGVPNTAAGEDADVAACPR---RGEEEEGGGGFPH 128
            P +P G  P G    +   +P G+P  P    G        P    +G   +GG     
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK--- 335

Query: 129 FGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSS----RPPS 184
              +   PPG+   PP    S +  A +PP    G   Q G     P  P+     +P +
Sbjct: 336 --PQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 393

Query: 185 PPAGLSTEPAGPGTAPRPFLPGQPAE 210
           PPAG   +P GP   P+   P +P +
Sbjct: 394 PPAG---QPQGPPRPPQGGRPSRPPQ 416



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 65/231 (28%), Positives = 78/231 (33%), Gaps = 48/231 (20%)

Query: 16  PRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGP--GELAARSPVLRG- 72
           P G P  P P+   +     SP            KP+    GP P  G      P   G 
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPP----------GKPQ----GPPPQGGNQPQGPPPPPGK 262

Query: 73  PQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPR---RGEEEEGGG---GF 126
           PQ P   GG  P G      P G+P  P    G  +  +  P    +G   +GG    G 
Sbjct: 263 PQGPPPQGGNKPQGPP----PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318

Query: 127 PHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGP----AASPPQEPSSRP 182
           P        PPG+   PP P+         PP    G  PQ G     A SPP +P    
Sbjct: 319 P-------PPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ--- 367

Query: 183 PSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPA 233
             PP      P GP   P    P QP      PP   P+ P   P    P+
Sbjct: 368 -GPPQQEGNNPQGP-PPPAGGNPQQPQA----PPAGQPQGPPRPPQGGRPS 412


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 78/304 (25%), Positives = 98/304 (32%), Gaps = 61/304 (20%)

Query: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
           P P+     SPR  P  P    P  G Q   P             P       GP     
Sbjct: 80  PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-------------PPPPGKPQGPPPQGG 126

Query: 66  RSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGG 125
             P  +GP  P +P G  P G K   +P   PG P             P+ G + +G   
Sbjct: 127 NRP--QGPPPPGKPQGPPPQGDKSR-SPRSPPGKPQGPP---------PQGGNQPQGPP- 173

Query: 126 FPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSP 185
                     PPG+   PP P+         PP    G  PQ G  +   Q P  +P  P
Sbjct: 174 ---------PPPGKPQGPP-PQGGKKPQGPPPPGKPQGPPPQ-GDKSRSSQSPPGKPQGP 222

Query: 186 PAGLSTEPAGPGTAPRPFLPGQPAEVDGN-----PPPAAPEAPAASPSTASPAPAAPGDL 240
           P     +P GP   P P  P  P    GN     PPP  P+ P A   + S +  +P   
Sbjct: 223 PPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK 280

Query: 241 RQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQP 300
            Q                 G      +  +GP  P    P +  A     P  PPR  Q 
Sbjct: 281 PQ-----------------GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 323

Query: 301 RRPA 304
            RP+
Sbjct: 324 GRPS 327



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 82/335 (24%), Positives = 109/335 (32%), Gaps = 81/335 (24%)

Query: 38  LCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP 97
           + L  L+   LA   A +L     +  + S +   PQ P   GG  P G      P G+P
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPP---PPPGKP 57

Query: 98  GVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAP 157
             P             P+ G + +G             PPG+   PP   + + S  S P
Sbjct: 58  QGPP------------PQGGNKPQGP-----------PPPGKPQGPPPQGDKSRSPRSPP 94

Query: 158 PRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPP 217
            +P  G  PQ G     P  P  +P  PP      P GP                  PPP
Sbjct: 95  GKPQ-GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP------------------PPP 135

Query: 218 AAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPA 277
             P+ P      +    + PG                    +G      +  +GP  PP 
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGK------------------PQGPPPQGGNQPQGPPPPPG 177

Query: 278 K--GPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKP 335
           K  GP     KK   P  PP   +P+ P P    + +         PP    G+     P
Sbjct: 178 KPQGPPPQGGKK---PQGPPPPGKPQGPPPQGDKSRSSQ------SPP----GKPQGPPP 224

Query: 336 ASSLRLQGDSKPPPAHPLWRWQMGG--PAVPEPPG 368
               + QG   PPP  P      GG  P  P PPG
Sbjct: 225 QGGNQPQG-PPPPPGKPQGPPPQGGNKPQGPPPPG 258



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 56/221 (25%), Positives = 71/221 (32%), Gaps = 35/221 (15%)

Query: 6   PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA 65
           P P+     SPR  P  P    P  G Q   P             P       GP     
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-------------PPPPGKPQGPPPQGG 187

Query: 66  RSPVLRGPQAPLRPGGWAPDGLKHL--WAPTGRPGVPNTAAGEDADVAACPR---RGEEE 120
           + P  +GP  P +P G  P G K     +P G+P  P    G        P    +G   
Sbjct: 188 KKP--QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245

Query: 121 EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSS 180
           +GG        +   PPG+   PP    S +  A +PP          G    PPQ+  +
Sbjct: 246 QGGNK-----PQGPPPPGKPQGPPAQGGSKSQSARSPP----------GKPQGPPQQEGN 290

Query: 181 RPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPE 221
            P  PP      P  P   P     G P    G  P   P+
Sbjct: 291 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 90/331 (27%), Positives = 106/331 (32%), Gaps = 80/331 (24%)

Query: 49  AKPRASSLGPGPGELAARS-PVLR--------GPQAPLRPGGWAPDGLKHLWAPTGRPGV 99
           A  R +S  P  G+L A   PVLR        G +    PG  AP            P +
Sbjct: 87  ANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPS-----------PRL 135

Query: 100 PNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPR 159
           PN          A PR G   E      H   R+  P    PAPP P          PP 
Sbjct: 136 PNKTISGPLIPPASPRLGNTSEA-----HGAARTAPPRPNVPAPPPP---------TPPP 181

Query: 160 PAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAA 219
           P P L         PP  PSS P   P      P GP T              GN P  A
Sbjct: 182 PPPPL---------PPPLPSSSPIKTPL---VSPPGPLTK-------------GNLPVVA 216

Query: 220 PEAPAASPSTASPAPAAPGDLRQEHF--DRLIRRSKLWCYAKGFALDTPSLRRGPERPPA 277
           P  P A P    P P  P  L       D+ ++      +        P L      PP 
Sbjct: 217 PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL------PPC 270

Query: 278 KGPARGAAKKRRLPAPPPRTAQ-PRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPA 336
             P   A      PA P + AQ P  P P LP  ++ S     P PP   V    +  P 
Sbjct: 271 GYPGLKAE-----PASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPP 325

Query: 337 SSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
              +      PP        + G  A+P PP
Sbjct: 326 LPPKSPSFQAPPQ-------KAGAQALPAPP 349



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 41/119 (34%), Positives = 49/119 (41%), Gaps = 17/119 (14%)

Query: 125 GFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPR---PAPGL----EPQRGPAASPPQE 177
           G+P       +P      PP P      +AS  PR   PAP L         P   PP+ 
Sbjct: 271 GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKS 330

Query: 178 PSSRPPSPPAGLSTEPAGPG-TAPRPFLP----GQPAEVDG--NPPPAAPEAPAASPST 229
           PS + P   AG    PA P     +PFL     G+P    G  NPPPA    PA SP+T
Sbjct: 331 PSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA---PPARSPTT 386



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 61/233 (26%), Positives = 77/233 (33%), Gaps = 39/233 (16%)

Query: 157 PPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGP------------GTAPRPF- 203
           PP P P L P   P  +PP  P S PP      S   A P            GT  R   
Sbjct: 4   PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63

Query: 204 -LPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFA 262
            +  + A    +      E   ++ +  +  P   GDL    F  ++R +     A G  
Sbjct: 64  QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP-VLRPAGQRDVAGGKT 122

Query: 263 LDTPSLR-----------RGPERPPAK----------GPARGAAKKRRLPAPPPRTAQPR 301
              P  R            GP  PPA           G AR A  +  +PAPPP T  P 
Sbjct: 123 GQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP 182

Query: 302 RP--APTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHP 352
            P   P LP++S        P P  L  G    + P           PPP  P
Sbjct: 183 PPPLPPPLPSSSPIKTPLVSP-PGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP 234



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 46/164 (28%), Positives = 61/164 (37%), Gaps = 27/164 (16%)

Query: 143 PPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRP 202
           PP P      +      PA   +  + P A PP  P     SP A L          P P
Sbjct: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASL----------PAP 311

Query: 203 FLPGQPAEVDGNPPPAAPEAPA--ASPSTAS----PAPAAPGDLRQEHFDRLIRRSKLWC 256
            LPG  +  +  PPP  P++P+  A P  A     PAP AP     + F +  R  +   
Sbjct: 312 PLPGVNSSSE-TPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG--SQPFLQKKRHGRPG- 367

Query: 257 YAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQP 300
            A G  L+       P  PPA+ P    + K +       T QP
Sbjct: 368 -AGGGKLNP------PPAPPARSPTTELSSKSQQATAWTPTQQP 404


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 102/403 (25%), Positives = 140/403 (34%), Gaps = 78/403 (19%)

Query: 7   APRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAAR 66
           AP L V  +P+  P   TP  P    Q  +    +A    A A P+A++  P PG  ++ 
Sbjct: 616 APVLTVQPAPQAPPAVSTPL-PLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSP 674

Query: 67  SPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGF 126
             ++ G      P          ++ P  R   P +A G    V A              
Sbjct: 675 EKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASV------------ 722

Query: 127 PHFGVRSCAPPGRCPAP-----------PHPRESTTSFASAPPRPAPGLEPQRGPAASP- 174
               + S  PP + PAP           P   +S  S A AP  PA       GP++SP 
Sbjct: 723 ----IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPS 778

Query: 175 -----------------PQEPSSRPPSPPAGLSTEPAGPGTAP------RPFLPGQPAEV 211
                            P  P SRPPS P  +S  P+ P   P       P LPG     
Sbjct: 779 LPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQ 838

Query: 212 D--GNPPPAAPEAPAA-----------SPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYA 258
           +  G PPPA+  AP A           S     P P AP          +   S+    +
Sbjct: 839 NQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSET---S 895

Query: 259 KGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRT-AQPRRPAPTLPTTSTFSLLN 317
                 TPS  +  + PP++GP        + P PPP     P   AP  P   TF ++ 
Sbjct: 896 SRLPAPTPSDFQ-LQFPPSQGP-------HKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT 947

Query: 318 C-FPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMG 359
             FP  P      +   +  S + LQ  +   PA P     +G
Sbjct: 948 TPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLG 990



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 96/351 (27%), Positives = 128/351 (36%), Gaps = 76/351 (21%)

Query: 60  PGELAARSPVLRGPQAPLRPGGWA--------PDGLKHLWAPTG--RPGVPNTAAGEDAD 109
           P  LAA S   +   AP  P            P  +  L  P G  +P  P  A GE A 
Sbjct: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAP 617

Query: 110 VAACPRRGEEEEGGGGFPHFGVRSCAPPG-RCPAPPHPRESTTSFASAPPRPAPGLEPQR 168
           V       +            V +  P G + P    P ++ T  A+APP+ A   +P  
Sbjct: 618 VLTVQPAPQAPPA--------VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ-ATTPQPSP 668

Query: 169 GPAASPPQEPSSRPPSP-PAGLSTEPA-----------GPGTAPRPFLPGQPAEVDGNPP 216
           G A+SP +    +PPS  P  + T+ +            P +A  P L    + +   PP
Sbjct: 669 GLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP 728

Query: 217 PAAPEAPA------------ASPSTASPAPA----APGDLR---QEHFDRLIRRSKLWCY 257
           PA   APA            A  S ASPAPA    A   L+         L  ++ L   
Sbjct: 729 PAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG-- 786

Query: 258 AKGFALDTPSLRRG-PERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLL 316
                 D+P L    P RPP++ P+R  +  R    PP     P +  PTLP    F + 
Sbjct: 787 ------DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLP--GIFVIQ 838

Query: 317 NCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
           N    PP           PAS+      + P P  P  R Q   P  P PP
Sbjct: 839 NQLGVPP-----------PASN---PAPTAPGPPQPPLRPQSQPPEGPLPP 875



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 84/337 (24%), Positives = 111/337 (32%), Gaps = 67/337 (19%)

Query: 6   PAPRLAVP---ASPRGSP-CSPTPRKPCRGTQ-EFSPLCLRALAFCALAKPRASSLGP-- 58
           P P+ A P    +P+ SP  + +P K   G     +P  +       +  P+  S  P  
Sbjct: 651 PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS 710

Query: 59  --GPGELAARSPVLRGPQ-----APLRP----GGWAPDGLKHLWAPTGRPGVPNTAAGED 107
             GP      S ++  P      AP  P     G  P       +P   P +P  A  + 
Sbjct: 711 AEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG 770

Query: 108 ADVAACPRRGEEEEGGGGFPHF-GVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEP 166
              ++ P    +   G   PH        PP R P+ P       S     P P P   P
Sbjct: 771 PGPSSSPSLPHQAPLGDS-PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPP 829

Query: 167 ----------QRG--PAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGN 214
                     Q G  P AS P   +  PP PP    ++P      P P L          
Sbjct: 830 TLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL---------- 879

Query: 215 PPPAAPEAPAASPSTASPAPA-APGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPE 273
           PP +   A A+S  T+S  PA  P D                     F L  P   +GP 
Sbjct: 880 PPSSTSSAVASSSETSSRLPAPTPSD---------------------FQLQFPP-SQGPH 917

Query: 274 RPPAKGPARGAAKKRRL-PAPPPRTAQ-PRRPAPTLP 308
           + P   P      +    P PPPRT Q    P P LP
Sbjct: 918 KSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALP 954



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 26/227 (11%)

Query: 144  PHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPR-P 202
            P P  +T   A  PPRP P   P  G        P      PPA    +P   GTAP  P
Sbjct: 1333 PPPPPATLKVAEPPPRPPPP-PPPTGQMNGTVDHP------PPAAPERKPL--GTAPHCP 1383

Query: 203  FLPGQPAEVDGNPPPAAPE-APAASPSTASPAP-AAPGDLRQEHFDRLIRRSKLWCYAKG 260
             LP +    +    P APE  PA      SPAP  A  D       R +   +   Y + 
Sbjct: 1384 RLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQR- 1442

Query: 261  FALDTPSLRRGPERPPAKGPARGAAKKR-RLPAPPPRTAQPRRPAPTLPTTSTFSLLNCF 319
                   + +GP   PA   A+G        P  PP     +R     P     S  +  
Sbjct: 1443 -------MLKGPPPEPAASAAQGTGDPDWEAPGLPP----AKRRKSESPDVDQASFSSDS 1491

Query: 320  PCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEP 366
            P    L       +    +L+      P P++P      G PA P P
Sbjct: 1492 PQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYP-HAASAGTPASPPP 1537



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 23/61 (37%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 177  EPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAA 236
            +P  +PP PPA L      P   P P   GQ      +PPPAAPE       TA   P  
Sbjct: 1328 DPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPL--GTAPHCPRL 1385

Query: 237  P 237
            P
Sbjct: 1386 P 1386



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 59/223 (26%), Positives = 76/223 (34%), Gaps = 54/223 (24%)

Query: 127  PHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRP---- 182
            P   ++   PP R P PP P          PP  AP  +P  G A   P+ P  +     
Sbjct: 1336 PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKP-LGTAPHCPRLPLRKTYREN 1394

Query: 183  ---PSPPAGLSTEPAG--PGTAPRPFLPGQPAEVDG---------------------NPP 216
               P  P G    PAG   G +P P     PA+VD                        P
Sbjct: 1395 VGGPGAPEG---TPAGRARGGSPAPL----PAKVDEATSGLIRELAAVEDELYQRMLKGP 1447

Query: 217  PAAPEAPAASPSTASPAPAAPG------------DLRQEHFDRLIRRSKLWCYAKGFALD 264
            P  P A AA   T  P   APG            D+ Q  F     +          A+D
Sbjct: 1448 PPEPAASAAQ-GTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAID 1506

Query: 265  T-PSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPT 306
            +  +L++ P R PA  P+   A     PA PP   +P    P+
Sbjct: 1507 SILNLQQAPGRTPA--PSYPHAASAGTPASPPPLHRPEAYPPS 1547



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 62/241 (25%), Positives = 78/241 (32%), Gaps = 46/241 (19%)

Query: 3   TLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLG---PG 59
           TL P P L     P GSP   T       T   +P+ +      AL  P +  L    P 
Sbjct: 207 TLQPIPGLQ--GLPNGSPGGATA-----ATLGLAPIQVVGQPVMALNTPTSQLLAKQVPV 259

Query: 60  PGELAARSPVLRGPQAP--LRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
            G LA+ +    GP  P  L   G +P G        G     N +A       A    G
Sbjct: 260 SGYLASAA----GPSEPVTLASAGVSPQG-------AGLVIQKNLSAA-----VATTLNG 303

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQE 177
               GG G       + AP G       P        S+P  PAP +   R P    P+ 
Sbjct: 304 NSVFGGAG------AASAPTGTPSG--QPLAVAPGLGSSPLVPAPNVILHRTPTPIQPK- 354

Query: 178 PSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAP 237
                   PAG+   P      P+PF P          P A P+ P A  +    A    
Sbjct: 355 --------PAGV-LPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA 405

Query: 238 G 238
           G
Sbjct: 406 G 406


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 52/175 (29%), Positives = 58/175 (33%), Gaps = 28/175 (16%)

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
           PGP       P     Q P RP    P        P G PG P         +A  P RG
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPP-------GPPGPPGPPPPGQVLPPPLAGPPNRG 270

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQE 177
           +                 PP   P  P  +         PP P PG  P  GP   PP  
Sbjct: 271 DRPP--------------PPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP---PP-- 311

Query: 178 PSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASP 232
           P   PP PP      P GP   P    P  P  + G PP A P AP  +P+   P
Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAP--PPHLPGPPPGAPPPAPHVNPAFFPP 364



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 57/207 (27%), Positives = 62/207 (29%), Gaps = 47/207 (22%)

Query: 158 PRPA-PGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPP 216
           P PA PG  P   PA   P  P   PP PP      P  PG    P L G P   D  PP
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPP--PGQVLPPPLAGPPNRGDRPPP 275

Query: 217 PAA-PEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERP 275
           P   P  P   P    P P  P                                  P   
Sbjct: 276 PVLFPGQPFGQPPLG-PLPPGP----------------------------------PPPV 300

Query: 276 PAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKP 335
           P  GP  G    ++ P PPP    PR P P  P   T +     P PP         + P
Sbjct: 301 PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL-TLAPPPHLPGPPPGAPPPAPHVNP 359

Query: 336 A-------SSLRLQGDSKPPPAHPLWR 355
           A       S +       PPP  P  R
Sbjct: 360 AFFPPPTNSGMPTSDSRGPPPTDPYGR 386



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 43/127 (33%), Positives = 46/127 (36%), Gaps = 16/127 (12%)

Query: 123 GGGFPHF--GVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQ---- 176
           GG  P F  G     PP   P PP P          PP P  G  P RG    PP     
Sbjct: 224 GGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPP-PLAG-PPNRGDRPPPPVLFPG 281

Query: 177 EPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAP-----EAPAASPSTAS 231
           +P  +PP  P      P  PG  P P   G P    G PPP  P       P   P T +
Sbjct: 282 QPFGQPPLGPLPPGPPPPVPGYGPPP---GPPPPQQGPPPPPGPFPPRPPGPLGPPLTLA 338

Query: 232 PAPAAPG 238
           P P  PG
Sbjct: 339 PPPHLPG 345



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 54/207 (26%), Positives = 64/207 (30%), Gaps = 56/207 (27%)

Query: 13  PASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRG 72
           P  P G P  P P  P    Q   P          LA P      P P  L    P  + 
Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPP---------PLAGPPNRGDRPPPPVLFPGQPFGQP 287

Query: 73  PQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVR 132
           P  PL PG   P  +     P G P                P++G               
Sbjct: 288 PLGPLPPG--PPPPVPGYGPPPGPPP---------------PQQGPPP------------ 318

Query: 133 SCAPPGRCPAPPHPREST-TSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLST 191
              PPG  P PP P          APP   PG  P   P  +P   P+  PP   +G+ T
Sbjct: 319 ---PPG--PFPPRPPGPLGPPLTLAPPPHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPT 372

Query: 192 -EPAGPGTAPRPFLPGQPAEVDGNPPP 217
            +  GP           P +  G PPP
Sbjct: 373 SDSRGP----------PPTDPYGRPPP 389



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 49/184 (26%), Positives = 50/184 (27%), Gaps = 42/184 (22%)

Query: 185 PPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEH 244
           PP G S      G   R   PG     D  P PA P  P   P  A   P  P       
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP-PPPFPAGQTPPRP------- 239

Query: 245 FDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPA 304
                                P    GP  PP   P  G      L  PP R  +P  P 
Sbjct: 240 ---------------------PLGPPGPPGPPGP-PPPGQVLPPPLAGPPNRGDRP--PP 275

Query: 305 PTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVP 364
           P L     F      P PP       G   P      Q    PPP          GP  P
Sbjct: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP----------GPFPP 325

Query: 365 EPPG 368
            PPG
Sbjct: 326 RPPG 329


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 85/274 (31%), Positives = 108/274 (39%), Gaps = 67/274 (24%)

Query: 136 PPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAG 195
           PPG  P P  P       ++APP P   LEP   P+ +PP  P     SPP  LS+ P+ 
Sbjct: 157 PPGGSPLPSPP-------STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSS-PSI 208

Query: 196 PGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLW 255
           P   P  F+P  P      PPP  P  PA +P    PAPA+P  +      RL     + 
Sbjct: 209 P--TPPDFIPPAPPLAFLAPPP--PPVPAPAP----PAPASPHTVG----TRLFPPGGVT 256

Query: 256 CYAKGFALD---TPSLRRGPERPPA--KGPARGAAKK------RRLPAPPP---RTA--- 298
            +    AL+     + R  P R PA  KG A G   +      R    PPP   RT+   
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316

Query: 299 -QPRRPAPTLPTTSTFSLLNCFPCPPALVVGE--------------DGDLK---PASSLR 340
            Q  + AP     +T    +  P PP+  +                 G+LK   PAS   
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376

Query: 341 LQGDSK-------PPPAHPLWRWQMGGPAVPEPP 367
            Q  S+       PPPA PL       PA P PP
Sbjct: 377 GQSQSQADERAGTPPPAPPL-----PPPAPPLPP 405



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 69/241 (28%), Positives = 85/241 (35%), Gaps = 40/241 (16%)

Query: 6   PAPRLAV---PASPRGSPCSPTPRKPCR-GTQEFSPLCLRALAFCALAKPRAS-SLGPGP 60
           PAP LA    P  P  +P  P P  P   GT+ F P          + K ++  +L    
Sbjct: 217 PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP--------GGVTKWKSDVALNGRQ 268

Query: 61  GELAARSPVLRGPQAPLRPGGWA--PDGLKHLWAPTGRPGVPNTAAGEDA-DVAACPRRG 117
            E    SP    P++P  P G A  P+   HL  P      P T     +  V       
Sbjct: 269 AEATRASP----PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQE 177
            +EEG          +   P R P PP          S   RPA  + P R P    P E
Sbjct: 325 RKEEGA---------TKKAPSRLPLPP----------SFHIRPASQVYPDRAPEPDCPGE 365

Query: 178 -PSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAA 236
             ++ P SP  G S   A       P  P  P      PPPA P  PAA P   +   A 
Sbjct: 366 LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH 425

Query: 237 P 237
           P
Sbjct: 426 P 426



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/136 (30%), Positives = 47/136 (34%), Gaps = 31/136 (22%)

Query: 175 PQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAP 234
           P  P    P PP  +S EP  PG +P   LP  P+     PPP     P   PS A P P
Sbjct: 140 PPPPPGPAPGPPQDIS-EP--PGGSP---LPSPPSTAP--PPPPLLLEPPPPPSMAPPPP 191

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPP 294
                L   H                  L +PS+   P+  P   P         L  PP
Sbjct: 192 PVLEALSPPH-----------------TLSSPSIPTPPDFIPPAPPL------AFLAPPP 228

Query: 295 PRTAQPRRPAPTLPTT 310
           P    P  PAP  P T
Sbjct: 229 PPVPAPAPPAPASPHT 244



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 55/191 (28%), Positives = 73/191 (38%), Gaps = 39/191 (20%)

Query: 136 PPGRCPAPPHPRESTTSFASAPPR----PAPGLEPQRGP-----AASPPQEPSSRPPSP- 185
           PP   P P  P ++T  + + PP+    PA  L+   GP     A S P   S+    P 
Sbjct: 642 PPKATPEPAIPPKATL-WPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700

Query: 186 ------------PAGLSTEPAGP--GTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS 231
                       PAG   +PA     T  +    G P+E    P   A  + A  P T S
Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT-S 759

Query: 232 PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRR-- 289
           P       L + H      +S L   ++  A+  P+L RG     A GP      K    
Sbjct: 760 PGGGEVPCLYKPH----CHQSSL---SREVAVVMPTLARGG----AAGPGEPVEVKEPPG 808

Query: 290 LPAPPPRTAQP 300
           LPA PP +AQP
Sbjct: 809 LPAKPPASAQP 819



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 46/167 (27%), Positives = 61/167 (36%), Gaps = 22/167 (13%)

Query: 146 PRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFL- 204
           P +STT   +   +P   L P   P A+P       P  PP         P T P+  L 
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATP------EPAIPPKA----TLWPATPPKATLG 668

Query: 205 PGQPAEVDGNP--PPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFA 262
           P  P +    P  P  A   PA + STA+  P     L  E       + +         
Sbjct: 669 PATPLKATSGPTTPLKATSGPAIA-STATTLPTTTSQLMAEKDSGPAGQPE---KPASQE 724

Query: 263 LDTPSLRRGPERP--PAKGPARGAAKKRRLPAPPPRTAQPRRPAPTL 307
           + TPS  RG   P    + P +GA   R   A PP+T+      P L
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGA---RSSAAFPPKTSPGGGEVPCL 768


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 85/274 (31%), Positives = 108/274 (39%), Gaps = 67/274 (24%)

Query: 136 PPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAG 195
           PPG  P P  P       ++APP P   LEP   P+ +PP  P     SPP  LS+ P+ 
Sbjct: 157 PPGGSPLPSPP-------STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSS-PSI 208

Query: 196 PGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLW 255
           P   P  F+P  P      PPP  P  PA +P    PAPA+P  +      RL     + 
Sbjct: 209 P--TPPDFIPPAPPLAFLAPPP--PPVPAPAP----PAPASPHTVG----TRLFPPGGVT 256

Query: 256 CYAKGFALD---TPSLRRGPERPPA--KGPARGAAKK------RRLPAPPP---RTA--- 298
            +    AL+     + R  P R PA  KG A G   +      R    PPP   RT+   
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316

Query: 299 -QPRRPAPTLPTTSTFSLLNCFPCPPALVVGE--------------DGDLK---PASSLR 340
            Q  + AP     +T    +  P PP+  +                 G+LK   PAS   
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376

Query: 341 LQGDSK-------PPPAHPLWRWQMGGPAVPEPP 367
            Q  S+       PPPA PL       PA P PP
Sbjct: 377 GQSQSQADERAGTPPPAPPL-----PPPAPPLPP 405



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 69/241 (28%), Positives = 85/241 (35%), Gaps = 40/241 (16%)

Query: 6   PAPRLAV---PASPRGSPCSPTPRKPCR-GTQEFSPLCLRALAFCALAKPRAS-SLGPGP 60
           PAP LA    P  P  +P  P P  P   GT+ F P          + K ++  +L    
Sbjct: 217 PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP--------GGVTKWKSDVALNGRQ 268

Query: 61  GELAARSPVLRGPQAPLRPGGWA--PDGLKHLWAPTGRPGVPNTAAGEDA-DVAACPRRG 117
            E    SP    P++P  P G A  P+   HL  P      P T     +  V       
Sbjct: 269 AEATRASP----PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQE 177
            +EEG          +   P R P PP          S   RPA  + P R P    P E
Sbjct: 325 RKEEGA---------TKKAPSRLPLPP----------SFHIRPASQVYPDRAPEPDCPGE 365

Query: 178 -PSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAA 236
             ++ P SP  G S   A       P  P  P      PPPA P  PAA P   +   A 
Sbjct: 366 LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH 425

Query: 237 P 237
           P
Sbjct: 426 P 426



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/136 (30%), Positives = 47/136 (34%), Gaps = 31/136 (22%)

Query: 175 PQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAP 234
           P  P    P PP  +S EP  PG +P   LP  P+     PPP     P   PS A P P
Sbjct: 140 PPPPPGPAPGPPQDIS-EP--PGGSP---LPSPPSTAP--PPPPLLLEPPPPPSMAPPPP 191

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPP 294
                L   H                  L +PS+   P+  P   P         L  PP
Sbjct: 192 PVLEALSPPH-----------------TLSSPSIPTPPDFIPPAPPL------AFLAPPP 228

Query: 295 PRTAQPRRPAPTLPTT 310
           P    P  PAP  P T
Sbjct: 229 PPVPAPAPPAPASPHT 244



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 55/191 (28%), Positives = 73/191 (38%), Gaps = 39/191 (20%)

Query: 136 PPGRCPAPPHPRESTTSFASAPPR----PAPGLEPQRGP-----AASPPQEPSSRPPSP- 185
           PP   P P  P ++T  + + PP+    PA  L+   GP     A S P   S+    P 
Sbjct: 642 PPKATPEPAIPPKATL-WPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700

Query: 186 ------------PAGLSTEPAGP--GTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS 231
                       PAG   +PA     T  +    G P+E    P   A  + A  P T S
Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT-S 759

Query: 232 PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRR-- 289
           P       L + H      +S L   ++  A+  P+L RG     A GP      K    
Sbjct: 760 PGGGEVPCLYKPH----CHQSSL---SREVAVVMPTLARGG----AAGPGEPVEVKEPPG 808

Query: 290 LPAPPPRTAQP 300
           LPA PP +AQP
Sbjct: 809 LPAKPPASAQP 819



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 46/167 (27%), Positives = 61/167 (36%), Gaps = 22/167 (13%)

Query: 146 PRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFL- 204
           P +STT   +   +P   L P   P A+P       P  PP         P T P+  L 
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATP------EPAIPPKA----TLWPATPPKATLG 668

Query: 205 PGQPAEVDGNP--PPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFA 262
           P  P +    P  P  A   PA + STA+  P     L  E       + +         
Sbjct: 669 PATPLKATSGPTTPLKATSGPAIA-STATTLPTTTSQLMAEKDSGPAGQPE---KPASQE 724

Query: 263 LDTPSLRRGPERP--PAKGPARGAAKKRRLPAPPPRTAQPRRPAPTL 307
           + TPS  RG   P    + P +GA   R   A PP+T+      P L
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGA---RSSAAFPPKTSPGGGEVPCL 768


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 85/274 (31%), Positives = 108/274 (39%), Gaps = 67/274 (24%)

Query: 136 PPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAG 195
           PPG  P P  P       ++APP P   LEP   P+ +PP  P     SPP  LS+ P+ 
Sbjct: 157 PPGGSPLPSPP-------STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSS-PSI 208

Query: 196 PGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLW 255
           P   P  F+P  P      PPP  P  PA +P    PAPA+P  +      RL     + 
Sbjct: 209 P--TPPDFIPPAPPLAFLAPPP--PPVPAPAP----PAPASPHTVG----TRLFPPGGVT 256

Query: 256 CYAKGFALD---TPSLRRGPERPPA--KGPARGAAKK------RRLPAPPP---RTA--- 298
            +    AL+     + R  P R PA  KG A G   +      R    PPP   RT+   
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316

Query: 299 -QPRRPAPTLPTTSTFSLLNCFPCPPALVVGE--------------DGDLK---PASSLR 340
            Q  + AP     +T    +  P PP+  +                 G+LK   PAS   
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376

Query: 341 LQGDSK-------PPPAHPLWRWQMGGPAVPEPP 367
            Q  S+       PPPA PL       PA P PP
Sbjct: 377 GQSQSQADERAGTPPPAPPL-----PPPAPPLPP 405



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 69/241 (28%), Positives = 85/241 (35%), Gaps = 40/241 (16%)

Query: 6   PAPRLAV---PASPRGSPCSPTPRKPCR-GTQEFSPLCLRALAFCALAKPRAS-SLGPGP 60
           PAP LA    P  P  +P  P P  P   GT+ F P          + K ++  +L    
Sbjct: 217 PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP--------GGVTKWKSDVALNGRQ 268

Query: 61  GELAARSPVLRGPQAPLRPGGWA--PDGLKHLWAPTGRPGVPNTAAGEDA-DVAACPRRG 117
            E    SP    P++P  P G A  P+   HL  P      P T     +  V       
Sbjct: 269 AEATRASP----PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 118 EEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQE 177
            +EEG          +   P R P PP          S   RPA  + P R P    P E
Sbjct: 325 RKEEGA---------TKKAPSRLPLPP----------SFHIRPASQVYPDRAPEPDCPGE 365

Query: 178 -PSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAA 236
             ++ P SP  G S   A       P  P  P      PPPA P  PAA P   +   A 
Sbjct: 366 LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH 425

Query: 237 P 237
           P
Sbjct: 426 P 426



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/136 (30%), Positives = 47/136 (34%), Gaps = 31/136 (22%)

Query: 175 PQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAP 234
           P  P    P PP  +S EP  PG +P   LP  P+     PPP     P   PS A P P
Sbjct: 140 PPPPPGPAPGPPQDIS-EP--PGGSP---LPSPPSTAP--PPPPLLLEPPPPPSMAPPPP 191

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPP 294
                L   H                  L +PS+   P+  P   P         L  PP
Sbjct: 192 PVLEALSPPH-----------------TLSSPSIPTPPDFIPPAPPL------AFLAPPP 228

Query: 295 PRTAQPRRPAPTLPTT 310
           P    P  PAP  P T
Sbjct: 229 PPVPAPAPPAPASPHT 244



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 55/191 (28%), Positives = 73/191 (38%), Gaps = 39/191 (20%)

Query: 136 PPGRCPAPPHPRESTTSFASAPPR----PAPGLEPQRGP-----AASPPQEPSSRPPSP- 185
           PP   P P  P ++T  + + PP+    PA  L+   GP     A S P   S+    P 
Sbjct: 642 PPKATPEPAIPPKATL-WPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700

Query: 186 ------------PAGLSTEPAGP--GTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS 231
                       PAG   +PA     T  +    G P+E    P   A  + A  P T S
Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT-S 759

Query: 232 PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRR-- 289
           P       L + H      +S L   ++  A+  P+L RG     A GP      K    
Sbjct: 760 PGGGEVPCLYKPH----CHQSSL---SREVAVVMPTLARGG----AAGPGEPVEVKEPPG 808

Query: 290 LPAPPPRTAQP 300
           LPA PP +AQP
Sbjct: 809 LPAKPPASAQP 819



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 46/167 (27%), Positives = 61/167 (36%), Gaps = 22/167 (13%)

Query: 146 PRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFL- 204
           P +STT   +   +P   L P   P A+P       P  PP         P T P+  L 
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATP------EPAIPPKA----TLWPATPPKATLG 668

Query: 205 PGQPAEVDGNP--PPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFA 262
           P  P +    P  P  A   PA + STA+  P     L  E       + +         
Sbjct: 669 PATPLKATSGPTTPLKATSGPAIA-STATTLPTTTSQLMAEKDSGPAGQPE---KPASQE 724

Query: 263 LDTPSLRRGPERP--PAKGPARGAAKKRRLPAPPPRTAQPRRPAPTL 307
           + TPS  RG   P    + P +GA   R   A PP+T+      P L
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGA---RSSAAFPPKTSPGGGEVPCL 768


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 76/250 (30%), Positives = 92/250 (36%), Gaps = 32/250 (12%)

Query: 8    PRLAVPASP------RGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPG 61
            P  A P  P       GSP +PT   P     +  P  +  +A  +   P A+ L  GP 
Sbjct: 1082 PACAAPGGPVITAFYSGSP-APTSSAPLAQPSQAPPSLVYTVA-TSTTPPAATILPKGPP 1139

Query: 62   ELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEE 121
              A  +P    P +P  P   A      L AP  +   P       A +A+ P  G  E 
Sbjct: 1140 APATATPA---PTSPF-PSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPV-GSFEA 1194

Query: 122  GGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSR 181
            G  G P    R    PG    P  P ES       PP P P       P    P   SS 
Sbjct: 1195 GASGRPGPAPRQPLEPGPVREPTAP-ESELEGQPTPPAPPPL------PETWTPTARSSP 1247

Query: 182  PPSPPAGLSTEPAGPGTAPRPF--------LPGQPAEVDGNP--PPAAPEAPAASP--ST 229
            P  PPA   T   GP T    F        +PGQ  E  G P  PP+   APA +P  S+
Sbjct: 1248 PLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSS 1307

Query: 230  ASPAPAAPGD 239
             S +  A GD
Sbjct: 1308 ESSSGRAAGD 1317



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 95/367 (25%), Positives = 122/367 (33%), Gaps = 79/367 (21%)

Query: 11   AVPASP--RGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAA--- 65
            +VP++P  +    SP    P  G+ +  P          LA P  S  G G G+      
Sbjct: 891  SVPSAPPPKAQSVSPVQAPPPGGSAQLLP----GKVLVPLAAPSMSVRGGGAGQPLPLVS 946

Query: 66   ---RSPVLRGPQAP-----LRPGGWA-PDGLKHLWAPTGRPGVPNTAAGEDADVAACPRR 116
                 PV  G Q P     L P   + P GL    +P   PG   T+  +   + +  R 
Sbjct: 947  PPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGP--TSQPQKVLLPSSTRI 1004

Query: 117  GEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRES-----TTSFASAPPRPAPGLEPQRGPA 171
               +  GG     G    +          P  S     T+   S P    P L   + P 
Sbjct: 1005 TYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPL 1064

Query: 172  ASPPQ---EPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNP------------- 215
             +P Q    P   P  PPA     P GP      F  G PA     P             
Sbjct: 1065 LAPGQVGVSPVPSPQLPPA--CAAPGGPVITA--FYSGSPAPTSSAPLAQPSQAPPSLVY 1120

Query: 216  -------PPAA---PEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDT 265
                   PPAA   P+ P A P+TA+PAP +P       F      S        ++L  
Sbjct: 1121 TVATSTTPPAATILPKGPPA-PATATPAPTSP-------FPSATAGSMT------YSLVA 1166

Query: 266  PSLRRGPERPPAKGPARGA--------AKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLN 317
            P  +R   + P K  A  A        A     P P PR  QP  P P    T+  S L 
Sbjct: 1167 PKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPR--QPLEPGPVREPTAPESELE 1224

Query: 318  CFPCPPA 324
              P PPA
Sbjct: 1225 GQPTPPA 1231



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 50/194 (25%), Positives = 66/194 (34%), Gaps = 30/194 (15%)

Query: 137  PGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGP 196
            P  C AP  P    T+F S  P P          +++P  +PS  PPS    ++T    P
Sbjct: 1081 PPACAAPGGP--VITAFYSGSPAPT---------SSAPLAQPSQAPPSLVYTVATSTTPP 1129

Query: 197  GTAPRPFLPGQPAEVDGNPPPAAPEAPAAS-------PSTASPAPAAPGDLRQEHFDRLI 249
                 P  P  PA     P    P A A S       P    P+P AP  ++       +
Sbjct: 1130 AATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPV 1189

Query: 250  RRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPT 309
               +     +        L  GP R P   P      +   PAPPP           LP 
Sbjct: 1190 GSFEAGASGRPGPAPRQPLEPGPVREPT-APESELEGQPTPPAPPP-----------LPE 1237

Query: 310  TSTFSLLNCFPCPP 323
            T T +  +  P PP
Sbjct: 1238 TWTPTARSSPPLPP 1251



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 49/200 (24%), Positives = 72/200 (36%), Gaps = 25/200 (12%)

Query: 3    TLCPAPRLAVPASPRGSPC---------SPTPRKPCRGTQEFSPLCLRALAFCALAKPRA 53
            T  PAP    P++  GS            P+P+ P +     + + + +    A  +P  
Sbjct: 1143 TATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP-- 1200

Query: 54   SSLGPGPGELAARSPVLRGPQAPL-----RPGGWAPDGLKHLWAPTGRPGVPNTAAGEDA 108
               GP P +     PV R P AP      +P   AP  L   W PT R   P     E+ 
Sbjct: 1201 ---GPAPRQPLEPGPV-REPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEER 1256

Query: 109  DVAACPR----RGEEEEGGGGFPHFGVRSCAPPGRCPAP-PHPRESTTSFASAPPRPAPG 163
              A  P     +          P  G+ +   P   P+P P P  +    + +    A G
Sbjct: 1257 TSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAG 1316

Query: 164  LEPQRGPAASPPQEPSSRPP 183
              P+R  AA   ++   RPP
Sbjct: 1317 DTPERKEAAGTGKKVKVRPP 1336



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 9/95 (9%)

Query: 156 APPRPAPGLEPQRG--PAASPPQEPSSRPPSPPAGLSTE--PAGPGTAPRPFLPGQPAEV 211
           AP +P P ++P     PA+ P     S+ P+  A ++ E  P G G+A     PG     
Sbjct: 45  APSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPE 104

Query: 212 DGNPPPAAPEAPAAS-----PSTASPAPAAPGDLR 241
              P P  P     S     P+T   A   PG+ R
Sbjct: 105 SPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPR 139



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 32/89 (35%), Positives = 38/89 (42%), Gaps = 15/89 (16%)

Query: 154  ASAPPRPAPGLE------PQRGPAASPPQEPSSR----PPSPPAGLSTEPAGPGTAPRPF 203
            A+ P    PG E      P  G AA+P   PS      P SP +   T  A P   P P 
Sbjct: 1521 AATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPE 1580

Query: 204  L-PGQPAEVDGNPPPAAPEAPAASPSTAS 231
              PGQP   +G P P+ P      PSTA+
Sbjct: 1581 SGPGQPGW-EGAPQPSPPPP---GPSTAA 1605



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 28/105 (26%), Positives = 37/105 (35%), Gaps = 3/105 (2%)

Query: 146 PRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLP 205
           P ES       PP      +P+R P A+ P+ P   PP  P G+     GP         
Sbjct: 74  PAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPH-PLGVVESGKGPPPTTEEEAS 132

Query: 206 GQPAE--VDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRL 248
           G P E  +D        +A  +  S     P  PG  R +    L
Sbjct: 133 GPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSAL 177



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 81/356 (22%), Positives = 107/356 (30%), Gaps = 69/356 (19%)

Query: 48  LAKPRASSLGPGPGELAAR----SPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTA 103
           L  P   + GP     A R     P     + P   GG  P G   + AP        + 
Sbjct: 571 LRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPP-------SG 623

Query: 104 AGEDADVAACPRRGEEEEGGGG------FPHFGVRSCAPPGRCPAPPHPRESTTSFASAP 157
            G        P   EE+EGGG        P     + A P   PA           +S P
Sbjct: 624 GGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTP 683

Query: 158 PRPAPGLEPQRGPAASPPQEP----------SSRPPSPPAGL----STEPAGPGTAPRPF 203
              A    P  G A + P +           S  P   P G+    S + +   T+P P 
Sbjct: 684 VPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPH 743

Query: 204 LPGQP-AEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFA 262
           L   P     G  P         +P   +PAP A   + Q         +       G  
Sbjct: 744 LVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQ--------GAPGGGTTAGSG 795

Query: 263 LDTPSLRRGPE-----RPPAKGPARGAAKKRRL---------------PAPPPRTAQPRR 302
               S   GP      +P A G A G  + + +               PAP  + A P  
Sbjct: 796 AGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSG 855

Query: 303 PAPTL-------PTTSTFS--LLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPP 349
           PAPT        P TST    L    P P   ++       P  +  +     PPP
Sbjct: 856 PAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPP 911



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 13/90 (14%)

Query: 136  PPGRCPAPPHPRESTTSFASAP-PRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPA 194
            PPG     P P  + T+ A AP P PA G +P      SP  +  +   +PP     E +
Sbjct: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDP-----TSPSSDSGTAQAAPPLPPPPE-S 1581

Query: 195  GPGTAPRPFLPGQPAEVDGNPPPAAPEAPA 224
            GPG       PG       +PPP  P   A
Sbjct: 1582 GPGQ------PGWEGAPQPSPPPPGPSTAA 1605



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 22/81 (27%), Positives = 29/81 (35%)

Query: 158 PRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPP 217
           P PAP    +    + P    S R   PP   +       TAP P +P   +     PP 
Sbjct: 840 PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899

Query: 218 AAPEAPAASPSTASPAPAAPG 238
           A   +P  +P     A   PG
Sbjct: 900 AQSVSPVQAPPPGGSAQLLPG 920



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 35/117 (29%), Positives = 46/117 (39%), Gaps = 17/117 (14%)

Query: 127 PHFGVRSCAPPGRCPAPP-----HPRESTTSFASAPPRPAPGLE-PQRGPAASPPQEPSS 180
           P  G ++ AP G  P         P  ST     A   P PG+   Q  P+A PP+  S 
Sbjct: 844 PAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSV 903

Query: 181 RP-PSPPAGLSTE---------PAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASP 227
            P  +PP G S +          A P  + R    GQP  +  +PP + P    A P
Sbjct: 904 SPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPL-VSPPFSVPVQNGAQP 959



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 4/60 (6%)

Query: 178  PSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAP 237
            P+ +PP   A L   P   GTA  P     PA   G P P +P + + +   A P P  P
Sbjct: 1524 PTEQPPGAEAPLPVPPP-TGTAAAPAPTPSPA---GGPDPTSPSSDSGTAQAAPPLPPPP 1579



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 47/182 (25%), Positives = 63/182 (34%), Gaps = 40/182 (21%)

Query: 181 RPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDL 240
           RPP  P     EP GP   P  F         G    +AP + A+SP+++S + A    L
Sbjct: 507 RPPLDP-----EPPGPPDPPVAF---------GKGYGSAPSSSASSPASSSASAATSFSL 552

Query: 241 RQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQP 300
               F              G       LR  P  P A GPA  +   R LP  P    + 
Sbjct: 553 GSGTFK---------AQESGQGSTAGPLR--PPPPGAGGPATPSKATRFLPMDPATFRRK 601

Query: 301 R--------RPAPTL---PTTSTFSLLNCFPCPPALVVGEDGDLK----PASSLRLQGDS 345
           R         P P++   P +   ++L     PP     E G  +    PA SL     +
Sbjct: 602 RPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPA 661

Query: 346 KP 347
            P
Sbjct: 662 AP 663



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 17/101 (16%)

Query: 93  PTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGR-CPAPPHPRESTT 151
           P   P V +  + E A+ AA     E   GG G          PPG  CP  P P     
Sbjct: 61  PASHP-VASNQSKEPAESAAVAH--ERPPGGTG----SADPERPPGATCPESPGP----- 108

Query: 152 SFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTE 192
                PP P   +E  +GP  +  +E S  P  P     TE
Sbjct: 109 ----GPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE 145



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 26/92 (28%), Positives = 32/92 (34%), Gaps = 23/92 (25%)

Query: 205  PGQPAEVDGNPPPAAPEAPAASPSTAS-PAPAAPGDLRQEHFDRLIRRSKLWCYAKGFAL 263
            PG  A +   PP     APA +PS A  P P +P                      G A 
Sbjct: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSS------------------DSGTAQ 1570

Query: 264  DTPSLRRGPERPPAKGPARGAAKKRRLPAPPP 295
              P L      PP  GP +   +    P+PPP
Sbjct: 1571 AAPPL----PPPPESGPGQPGWEGAPQPSPPP 1598


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 97/379 (25%), Positives = 125/379 (32%), Gaps = 103/379 (27%)

Query: 29  CRGTQEFSPLCLRALAFCALAKPRASSLGPGPG--ELAARSPVLRGPQAPLRPGGWAPDG 86
           C+GT+      +   +   L KP+ SS G G G   L  +  + +G    LRP G A DG
Sbjct: 45  CKGTKLKKVTNINDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVG-AKDG 103

Query: 87  LKHLWA------PTGRPGVP----NTAAGEDADVAACPRRGEEE---------------- 120
            ++L        P+ R   P    + A+G   D     R    E                
Sbjct: 104 SENLAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPN 163

Query: 121 -EGGGGFPHFGVRSCAPPG--RCPAPPHPRESTTSFASA-------PPRPAPGLEPQRGP 170
                G  H       PP   R  APP P    +S A A       PP P   L P R  
Sbjct: 164 TTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGR-- 221

Query: 171 AASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTA 230
              PP  P  +PP  P  + T P+G   AP              PPP   + P      +
Sbjct: 222 -EGPPAPPPVKPPPSPVNIRTGPSGQSLAP--------------PPPPYRQPPGVPNGPS 266

Query: 231 SPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRL 290
           SP   +  +L Q H                      SL R        GP RG A     
Sbjct: 267 SPTNESAPELPQRH---------------------NSLHR-----KTPGPVRGLA----- 295

Query: 291 PAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASS--LRLQGDSKPP 348
             PPP            PT+++ SLL+  P PPA      G   P     +R      PP
Sbjct: 296 --PPP------------PTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPP 341

Query: 349 PAHPLWRWQMGGPAVPEPP 367
           P  P        P+  +PP
Sbjct: 342 PPPPYRMHGSEPPSRGKPP 360



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 67/254 (26%), Positives = 84/254 (33%), Gaps = 42/254 (16%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARS 67
           P        + S  +P P  P R      P  L   +  A A  R   L P PG+     
Sbjct: 162 PNTTSSTGMKHSSSAPPPPPPGRRANA-PPTPLPMHSSKAPAYNREKPLPPTPGQRL--H 218

Query: 68  PVLRGPQAPLRPGGWAPDGLKHLWAPTGR------------PGVPNTAAGEDADVAA-CP 114
           P   GP AP  P    P  +     P+G+            PGVPN  +    + A   P
Sbjct: 219 PGREGPPAP-PPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELP 277

Query: 115 RRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASP 174
           +R               R    P R  APP P  ++ S  S  P P         PA  P
Sbjct: 278 QRHNSLH----------RKTPGPVRGLAPPPPTSASPSLLSNRPPP---------PARDP 318

Query: 175 PQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAP 234
           P   ++ PP PP   +     P   P   + G      G PPP     P      A P P
Sbjct: 319 PSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTP------AGPPP 372

Query: 235 AAPGDLRQEHFDRL 248
             P  LR  H D +
Sbjct: 373 PPPPPLRNGHRDSI 386



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 67/242 (27%), Positives = 81/242 (33%), Gaps = 39/242 (16%)

Query: 17  RGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAP 76
           R  P +P P KP       SP+ +R         P   SL P P        V  GP +P
Sbjct: 221 REGPPAPPPVKPPP-----SPVNIRT-------GPSGQSLAPPPPPYRQPPGVPNGPSSP 268

Query: 77  LRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAP 136
                 AP+       P     +     G    +A  P            P    R   P
Sbjct: 269 TNES--APE------LPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARD--P 318

Query: 137 PGRCPAPPHPRESTTSFA-SAPPRPAP----GLEP-QRGPAASPPQE-PSSRPPSPPAGL 189
           P R  APP P     + A  APP P P    G EP  RG    PP   P+  PP PP  L
Sbjct: 319 PSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPL 378

Query: 190 STEPAGPGTAPRPFLPGQPAEVDGNPPP--AAPEA--------PAASPSTASPAPAAPGD 239
                   T  R FL    ++   +P     APE         P+ +   A  AP  P  
Sbjct: 379 RNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRIYPSKTNRAARGAPPLPPI 438

Query: 240 LR 241
           LR
Sbjct: 439 LR 440


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 53/178 (29%), Positives = 58/178 (32%), Gaps = 46/178 (25%)

Query: 142 APPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPR 201
           +P HP  +      +PP P PG  P   P   PP      PP PP G  +    PGT P 
Sbjct: 296 SPSHPPPAPP--LGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGS----PGTPPP 349

Query: 202 PFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGF 261
           P  P  P   D   PP  P  PAA   T  P P                           
Sbjct: 350 PSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP--------------------------- 382

Query: 262 ALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRT---AQPRRPAPTLPTTSTFSLL 316
            L  P+    P  PP   P          P PPP T    QP  P P   TT   S L
Sbjct: 383 -LSQPTGGAPPPPPPPPPPG---------PPPPPFTGADGQPAIPPPLSDTTKPKSSL 430



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 68/219 (31%), Positives = 79/219 (36%), Gaps = 43/219 (19%)

Query: 143 PPHPRESTTSFASA-------PPRPAPGLEP---QRGPAASPPQ-----EPSSRPPSPPA 187
           PP P+  + S  S        PP PA    P   QRG   + P+      PS  PP+PP 
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306

Query: 188 GLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDR 247
           G    P  PG AP P  P  P  + G PPP  P     SP T  P P +P      H D 
Sbjct: 307 GSPPGPK-PGFAPPPAPPPPPPPMIGIPPP-PPPVGFGSPGT--PPPPSPPSF-PPHPDF 361

Query: 248 LIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTL 307
                         A D P+L      PP   P  GA      P PPP    P  P P  
Sbjct: 362 AAPPPP----PPPPAADYPTL----PPPPLSQPTGGA------PPPPPPPPPPGPPPP-- 405

Query: 308 PTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSK 346
           P T            PA+        KP SSL    D++
Sbjct: 406 PFTGADG-------QPAIPPPLSDTTKPKSSLPAVSDAR 437



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 39/118 (33%), Positives = 43/118 (36%), Gaps = 12/118 (10%)

Query: 135 APPGRCPAPPHPRESTTSFASAPPRPAPGLEPQR------GPAASPPQEPSSRPPSPPAG 188
           APP   P  P P  +       PP P  G+ P         P   PP  P S PP P   
Sbjct: 303 APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFA 362

Query: 189 LSTEPAGPGTAPRPFLPGQP-AEVDGN----PPPAAPEAPAASPST-ASPAPAAPGDL 240
               P  P  A  P LP  P ++  G     PPP  P  P   P T A   PA P  L
Sbjct: 363 APPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL 420



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 36/109 (33%), Positives = 41/109 (37%), Gaps = 21/109 (19%)

Query: 129 FGVRSCAPPGRCPA-PPHPRESTTSFASAPPRPAPGLEPQRGPAASPP---QEPSSRPPS 184
           FG     PP   P+ PPHP      FA+ PP P P       P   PP   Q     PP 
Sbjct: 341 FGSPGTPPPPSPPSFPPHP-----DFAAPPPPPPPPAADY--PTLPPPPLSQPTGGAPPP 393

Query: 185 PPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPA 233
           PP      P  PG  P PF        DG P    P +    P ++ PA
Sbjct: 394 PP-----PPPPPGPPPPPF-----TGADGQPAIPPPLSDTTKPKSSLPA 432



 Score = 33.5 bits (75), Expect = 0.32
 Identities = 56/218 (25%), Positives = 66/218 (30%), Gaps = 67/218 (30%)

Query: 154 ASAPPRPAPGLEPQRGPAASP-PQEPSSRPPSPPAGLS---TEPAGPGTAPRPFLPGQPA 209
           AS+ P P     PQ   A+SP P       P PPA  S       G G A     P + +
Sbjct: 243 ASSYPPP-----PQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAG----PKRSS 293

Query: 210 EVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLR 269
            V  + PP AP  P  SP    P  A P                                
Sbjct: 294 VVSPSHPPPAP--PLGSPPGPKPGFAPP-------------------------------- 319

Query: 270 RGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGE 329
             P  PP   P  G      +P PPP         P  P+  +F     F  PP      
Sbjct: 320 --PAPPPPPPPMIG------IPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP----- 366

Query: 330 DGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
                P         + PPP  PL +   G P  P PP
Sbjct: 367 -----PPPPPAADYPTLPPP--PLSQPTGGAPPPPPPP 397



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 40/147 (27%), Positives = 50/147 (34%), Gaps = 32/147 (21%)

Query: 49  AKPRASSLGPGPGELAARSPV-----LRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTA 103
           A P  S  GP PG     +P      + G   P  P G+   G     +P   P  P+ A
Sbjct: 303 APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFA 362

Query: 104 AGED------ADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAP 157
           A         AD    P     +  GG           PP   P PP P          P
Sbjct: 363 APPPPPPPPAADYPTLPPPPLSQPTGGA---------PPPPPPPPPPGP----------P 403

Query: 158 PRPAPGLEPQRGPAASPPQEPSSRPPS 184
           P P  G + Q  PA  PP   +++P S
Sbjct: 404 PPPFTGADGQ--PAIPPPLSDTTKPKS 428


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 67/230 (29%), Positives = 80/230 (34%), Gaps = 37/230 (16%)

Query: 23  PTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGP-GELAARSPVLRGPQAPLRPGG 81
           P  R+P  G Q   P             P     GP P G   ++ P    P  P +P G
Sbjct: 36  PEGRRPQGGNQPQRP-----------PPPPGKPQGPPPQGGNQSQGP----PPPPGKPEG 80

Query: 82  WAPDGLKHLWAPTGRPGVPNTAA--GEDADVAACPRRGEEEEG---GGGFPHFGVRSCAP 136
             P G      P   PG P      G +      P  G+ E     GG   H   R   P
Sbjct: 81  RPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSH---RPPPP 137

Query: 137 PGRCPAPPHPRESTTSFASAPPRPAP--GLEPQRGPAASPPQEPSSRPPSPPAGLSTEPA 194
           PG+   PP P+    S    PP P    G  PQ G  +   + P  +P  PP     +P 
Sbjct: 138 PGKPERPP-PQGGNQS-QGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQ 195

Query: 195 GPGTAPRPFLPGQPAEVDGNP-----PPAA-PEAPAASPSTASPAPAAPG 238
           GP   P P  P  P    GNP     PPA  P+ P   P    P   A G
Sbjct: 196 GP---PPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQG 242



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 81/281 (28%), Positives = 98/281 (34%), Gaps = 57/281 (20%)

Query: 38  LCLRALAFCALAKPRASSLGPGPGE---LAARSPVLRGPQAPLRPGGWAPDGLKHLWAPT 94
           L L ++A  AL+   +SS      E   L +  P  R PQ   +P    P        P 
Sbjct: 3   LILLSVALLALSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPP--------PP 54

Query: 95  GRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFA 154
           G+P  P    G  +     P  G+ E   G  P  G +S  PP      PHP +      
Sbjct: 55  GKPQGPPPQGGNQSQ-GPPPPPGKPE---GRPPQGGNQSQGPP------PHPGK------ 98

Query: 155 SAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGN 214
             P RP P    Q      PP +P   PP         P  PG   RP  P Q       
Sbjct: 99  --PERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERP--PPQGGNQSQG 154

Query: 215 PP--PAAPEAPA-----ASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPS 267
           PP  P  PE P       S S  SP     G  +QE               K      P 
Sbjct: 155 PPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEG-------------NKPQGPPPPG 201

Query: 268 LRRGPERPPAKG----PARGAAKKRRLPAPPPRTAQPRRPA 304
             +GP  PPA G    P    A K + P PPP+  +P RPA
Sbjct: 202 KPQGP--PPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPA 240



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 58/211 (27%), Positives = 72/211 (34%), Gaps = 26/211 (12%)

Query: 13  PASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRG 72
           P  P G P  P P+    G Q   P            +    S GP P       P  +G
Sbjct: 50  PPPPPGKPQGPPPQG---GNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQG 106

Query: 73  -------PQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAA--GEDADVAACPRRGEEEEGG 123
                  P  P +P    P G      P   PG P      G +      P  G+ E   
Sbjct: 107 GNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPE--- 163

Query: 124 GGFPHFGVRSCA---PPGRCPAPPHPRESTTSFASAPPRPAPGLEPQ-RGPAASPPQEPS 179
           G  P  G +S +   PPG+   PP          + P  P P  +PQ   PA   PQ+P 
Sbjct: 164 GPPPQEGNKSRSARSPPGKPQGPPQQE------GNKPQGPPPPGKPQGPPPAGGNPQQPQ 217

Query: 180 SRPPSPPAGLSTEPAGPGTAPRPFLPGQPAE 210
           + P   P G    P G G  PRP    QP +
Sbjct: 218 APPAGKPQGPPPPPQG-GRPPRPAQGQQPPQ 247



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 26/98 (26%), Positives = 31/98 (31%), Gaps = 10/98 (10%)

Query: 270 RGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGE 329
           +GP  PP K   R      +   PPP   +P RP P     S  +     P PP      
Sbjct: 69  QGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGT-----PPPPG----- 118

Query: 330 DGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
             +  P           PPP  P      GG     PP
Sbjct: 119 KPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPP 156


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 68/238 (28%), Positives = 81/238 (34%), Gaps = 79/238 (33%)

Query: 137 PGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGP 196
           P R P PP P     S    PP PAPG               S+ PP PP         P
Sbjct: 568 PSRAPVPPAPPLPGDSGTIIPPPPAPG--------------DSTTPPPPP---------P 604

Query: 197 GTAPRPFLPGQPAEVDGNPPPAAPEAPAASP-------STASPAPAAPGDLRQEHFDRLI 249
              P P LPG    V  + PP+ P   A SP       +T  P P  P            
Sbjct: 605 PPPPPPPLPG---GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLP------------ 649

Query: 250 RRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPT 309
                    +G  + +PS   G    P   P  G+A   R+P PP          P LP 
Sbjct: 650 ---------EGVGIPSPSSLPGGTAIPPPPPLPGSA---RIPPPP----------PPLPG 687

Query: 310 TSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
           ++        P PP  + GE G   P   L       PPP  P      GGP +P PP
Sbjct: 688 SAG------IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP------GGPGIPPPP 733



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/191 (29%), Positives = 65/191 (34%), Gaps = 46/191 (24%)

Query: 141 PAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAP 200
           P PP P +STT     PP P P   P     +SPP  P     SPP  LS +   P   P
Sbjct: 588 PPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP 647

Query: 201 RPFLPG--QPAEVDGN----PPPAAPEA------PAASPSTAS---PAPAAPGDLRQEHF 245
            P   G   P+ + G     PPP  P +      P   P +A    P P  PG+      
Sbjct: 648 LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE------ 701

Query: 246 DRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRP-- 303
                         G     P L  GP  PP      G      +P PPP    P  P  
Sbjct: 702 -------------AGMPPPPPPLPGGPGIPPPPPFPGGPG----IPPPPPGMGMPPPPPF 744

Query: 304 ------APTLP 308
                 AP LP
Sbjct: 745 GFGVPAAPVLP 755


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 68/238 (28%), Positives = 81/238 (34%), Gaps = 79/238 (33%)

Query: 137 PGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGP 196
           P R P PP P     S    PP PAPG               S+ PP PP         P
Sbjct: 577 PSRAPVPPAPPLPGDSGTIIPPPPAPG--------------DSTTPPPPP---------P 613

Query: 197 GTAPRPFLPGQPAEVDGNPPPAAPEAPAASP-------STASPAPAAPGDLRQEHFDRLI 249
              P P LPG    V  + PP+ P   A SP       +T  P P  P            
Sbjct: 614 PPPPPPPLPG---GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLP------------ 658

Query: 250 RRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPT 309
                    +G  + +PS   G    P   P  G+A   R+P PP          P LP 
Sbjct: 659 ---------EGVGIPSPSSLPGGTAIPPPPPLPGSA---RIPPPP----------PPLPG 696

Query: 310 TSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPP 367
           ++        P PP  + GE G   P   L       PPP  P      GGP +P PP
Sbjct: 697 SAG------IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP------GGPGIPPPP 742



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/191 (29%), Positives = 65/191 (34%), Gaps = 46/191 (24%)

Query: 141 PAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAP 200
           P PP P +STT     PP P P   P     +SPP  P     SPP  LS +   P   P
Sbjct: 597 PPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP 656

Query: 201 RPFLPG--QPAEVDGN----PPPAAPEA------PAASPSTAS---PAPAAPGDLRQEHF 245
            P   G   P+ + G     PPP  P +      P   P +A    P P  PG+      
Sbjct: 657 LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE------ 710

Query: 246 DRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRP-- 303
                         G     P L  GP  PP      G      +P PPP    P  P  
Sbjct: 711 -------------AGMPPPPPPLPGGPGIPPPPPFPGGPG----IPPPPPGMGMPPPPPF 753

Query: 304 ------APTLP 308
                 AP LP
Sbjct: 754 GFGVPAAPVLP 764


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 87/323 (26%), Positives = 113/323 (34%), Gaps = 38/323 (11%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPGPGELAAR 66
           P+   P +P+  P   TP++P   T+E +P   +  A  A  KP  ++   P P      
Sbjct: 314 PKEPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372

Query: 67  SPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGF 126
           +P      +P  P   AP   K     T  P    T +         P   +E       
Sbjct: 373 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----- 427

Query: 127 PHFGVRSCAPPGRCPAPPHPRE--STTSFASAP-----PRPAPGLEP-QRGPAASPPQEP 178
           P           + PAP  P+E   TT    AP     P P    EP    P  + P  P
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 487

Query: 179 SSRPPSPPAGLS-TEPAGPG-TAPRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP-AP 234
               P+ P  L+ T P  P  T P    P  P E    P P  PE PA  +P  A+P  P
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE----PTPTTPEEPAPTTPKAAAPNTP 543

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP- 293
             P     +       +       K  A  TP   +G      K PA    KK   PAP 
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP---KGTAPTTLKEPAPTTPKK---PAPK 597

Query: 294 ---PPRTAQPR-----RPAPTLP 308
              P  T +P      +PAPT P
Sbjct: 598 ELAPTTTKEPTSTTCDKPAPTTP 620



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 78/331 (23%), Positives = 110/331 (33%), Gaps = 45/331 (13%)

Query: 2   ETLCPAPRLAVPASPRGS----PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLG 57
           ET    P L  P  P  +    P S TP++P   T + +P   +        +P  ++  
Sbjct: 202 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--------EPAPTTTK 253

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
             P      +P      AP  P   AP   K   APT     P T           P   
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPT 312

Query: 118 EEEEGGGGFPHFGV----RSCAPPGRCPAPPHPRESTTSFA-------------SAPPRP 160
             +E     P        +  AP  + PAP  P+E   +               + P  P
Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372

Query: 161 APGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAA 219
           AP     + P+ + P+EP+          + EPA   T   P  P +P+      P P  
Sbjct: 373 AP--TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430

Query: 220 PEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKG 279
           P+ PA + +   PAP  P +           +       K  A  TP     P  P    
Sbjct: 431 PKEPAPT-TPKKPAPTTPKEPAP-----TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETA 483

Query: 280 PARGAAKKRRLPAPPPRTA--QPRRPAPTLP 308
           P      K+  P  P + A   P +PAPT P
Sbjct: 484 P---TTPKKLTPTTPEKLAPTTPEKPAPTTP 511



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 69/256 (26%), Positives = 94/256 (36%), Gaps = 40/256 (15%)

Query: 141 PAPPHPRE----STTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLST-EPAG 195
           PAP   +E    +T S  + P  PAP     + PA + P+EP+   P  P   +  EPA 
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 335

Query: 196 PGTAPRPFLPGQPA-EVDGNPPPAAPEAPA-------ASPSTASPAPAAPGDLRQEHFDR 247
               P P  P +PA      P P  P+ PA       A  +T  P+P  P +        
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395

Query: 248 LIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP----PPRTAQPRRP 303
               +K    A       P+  + P     K PA    K+   PAP     P    P+ P
Sbjct: 396 APTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE---PAPTTPKKPAPTTPKEP 450

Query: 304 APTLP----TTSTFSLLNCFPCPPALVVGED------GDLKPASSLRLQGDS--KPPPAH 351
           APT P     T+T       P  PA    ++        L P +  +L   +  KP P  
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510

Query: 352 PLWRWQMGGPAVPEPP 367
           P    +   P  PE P
Sbjct: 511 P----EELAPTTPEEP 522



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 51/188 (27%), Positives = 71/188 (37%), Gaps = 14/188 (7%)

Query: 132 RSCAPPGRCPAPPHPRESTTSFASA---PPRPAPGLEPQRGPAASPPQEPSSRPPSPPAG 188
           +  AP  +  A P P+  TT+   A   P  P P    +  PA++ P+EP+         
Sbjct: 185 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPT 242

Query: 189 LSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAAPEAPA------ASPSTASPAPAAPGDLR 241
              EPA   T   P  P +PA      P P  P+ PA       +P+T   AP  P +  
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 302

Query: 242 QEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP-PPRTAQP 300
                +    +            TP+  + P  P  K PA    K+    AP  P    P
Sbjct: 303 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP-APTTKEPAPTTPKEPAPTAPKKPAPTTP 361

Query: 301 RRPAPTLP 308
           + PAPT P
Sbjct: 362 KEPAPTTP 369



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 61/246 (24%), Positives = 90/246 (36%), Gaps = 40/246 (16%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASS-LGPGPGELA- 64
           P+   P +P+  P   TP++P   T +E +P   +  A   L +P  ++   P P ELA 
Sbjct: 543 PKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601

Query: 65  --ARSPVLR--GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEE 120
              + P        AP  P G AP   K     T +   P T  G        P   +E 
Sbjct: 602 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------TAPTTLKE- 654

Query: 121 EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPP-----RPAPGLEPQRGPAASPP 175
                          P    P  P P+E   +    P      +PAP    +  P  + P
Sbjct: 655 ---------------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP--TTP 697

Query: 176 QEPSSRPPSPPAGLSTEPAGPGTA--PRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP 232
           +EP+   P  PA  + E   P T+    P    +P  +  +P  + PE  A  +P     
Sbjct: 698 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 757

Query: 233 APAAPG 238
           +P  PG
Sbjct: 758 SPKEPG 763



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 75/316 (23%), Positives = 104/316 (32%), Gaps = 50/316 (15%)

Query: 6   PAP---RLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASSLGPGPG 61
           PAP   +   P +P+  P   TP++    T ++ +P     LA     KP  ++    P 
Sbjct: 458 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PE 512

Query: 62  ELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAA--CPRRGEE 119
           ELA  +P    P  P  P    P            P  P   A       A   P+    
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572

Query: 120 EEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPS 179
               G  P           + PAP     +TT   ++     P     +G A + P+EP+
Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632

Query: 180 SRPPSPPAGLSTEPAGPGT--APRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS--PAPA 235
              P  PA  + +   P T   P P  P +PA     P   AP       ST S  PAP 
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-----PKELAPTTTKGPTSTTSDKPAPT 687

Query: 236 APGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPP 295
            P +                          P+  + P     K PA    +      PPP
Sbjct: 688 TPKE------------------------TAPTTPKEPAPTTPKKPAPTTPE-----TPPP 718

Query: 296 RTAQPRRPAPTL-PTT 310
            T++   P  T  PTT
Sbjct: 719 TTSEVSTPTTTKEPTT 734



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 79/339 (23%), Positives = 109/339 (32%), Gaps = 45/339 (13%)

Query: 8   PRLAVPASPRGS-------PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPG 59
           P+   P +P+G+       P   TP+KP    +E +P   +        KP  ++  G  
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTPKGTA 624

Query: 60  PGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTG--RPG----VPNTAAGEDADVAAC 113
           P      +P      AP  P G AP  LK   APT   +P      P T  G  +  +  
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKGPTSTTSDK 683

Query: 114 PRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAAS 173
           P     +E     P     +  P    P  P     TTS  S P          + P  S
Sbjct: 684 PAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 742

Query: 174 PPQEPSSRPPSPPAGLSTEPAGPGT----APRPFLP----GQPAEVDGNPPP----AAPE 221
            P+  +   P        EP  P T    A +P +      +  E D    P    AAP+
Sbjct: 743 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 802

Query: 222 -----APAASPSTASPAPAAPGDLR----QEHFDRLIRRSKLWCYAKGFA-----LDTPS 267
                A     +T S   A    +     Q+     I   K    A         + T  
Sbjct: 803 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 862

Query: 268 LRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPT 306
           +   PE   AK   R    K   P P   T  P++P  T
Sbjct: 863 IMNKPEET-AKPKDRATNSKATTPKPQKPTKAPKKPTST 900


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 87/323 (26%), Positives = 113/323 (34%), Gaps = 38/323 (11%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPGPGELAAR 66
           P+   P +P+  P   TP++P   T+E +P   +  A  A  KP  ++   P P      
Sbjct: 355 PKEPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413

Query: 67  SPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGF 126
           +P      +P  P   AP   K     T  P    T +         P   +E       
Sbjct: 414 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----- 468

Query: 127 PHFGVRSCAPPGRCPAPPHPRE--STTSFASAP-----PRPAPGLEP-QRGPAASPPQEP 178
           P           + PAP  P+E   TT    AP     P P    EP    P  + P  P
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 528

Query: 179 SSRPPSPPAGLS-TEPAGPG-TAPRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP-AP 234
               P+ P  L+ T P  P  T P    P  P E    P P  PE PA  +P  A+P  P
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE----PTPTTPEEPAPTTPKAAAPNTP 584

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP- 293
             P     +       +       K  A  TP   +G      K PA    KK   PAP 
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP---KGTAPTTLKEPAPTTPKK---PAPK 638

Query: 294 ---PPRTAQPR-----RPAPTLP 308
              P  T +P      +PAPT P
Sbjct: 639 ELAPTTTKEPTSTTCDKPAPTTP 661



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 78/331 (23%), Positives = 110/331 (33%), Gaps = 45/331 (13%)

Query: 2   ETLCPAPRLAVPASPRGS----PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLG 57
           ET    P L  P  P  +    P S TP++P   T + +P   +        +P  ++  
Sbjct: 243 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--------EPAPTTTK 294

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
             P      +P      AP  P   AP   K   APT     P T           P   
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPT 353

Query: 118 EEEEGGGGFPHFGV----RSCAPPGRCPAPPHPRESTTSFA-------------SAPPRP 160
             +E     P        +  AP  + PAP  P+E   +               + P  P
Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413

Query: 161 APGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAA 219
           AP     + P+ + P+EP+          + EPA   T   P  P +P+      P P  
Sbjct: 414 AP--TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471

Query: 220 PEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKG 279
           P+ PA + +   PAP  P +           +       K  A  TP     P  P    
Sbjct: 472 PKEPAPT-TPKKPAPTTPKEPAP-----TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETA 524

Query: 280 PARGAAKKRRLPAPPPRTA--QPRRPAPTLP 308
           P      K+  P  P + A   P +PAPT P
Sbjct: 525 P---TTPKKLTPTTPEKLAPTTPEKPAPTTP 552



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 69/256 (26%), Positives = 94/256 (36%), Gaps = 40/256 (15%)

Query: 141 PAPPHPRE----STTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLST-EPAG 195
           PAP   +E    +T S  + P  PAP     + PA + P+EP+   P  P   +  EPA 
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 376

Query: 196 PGTAPRPFLPGQPA-EVDGNPPPAAPEAPA-------ASPSTASPAPAAPGDLRQEHFDR 247
               P P  P +PA      P P  P+ PA       A  +T  P+P  P +        
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436

Query: 248 LIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP----PPRTAQPRRP 303
               +K    A       P+  + P     K PA    K+   PAP     P    P+ P
Sbjct: 437 APTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE---PAPTTPKKPAPTTPKEP 491

Query: 304 APTLP----TTSTFSLLNCFPCPPALVVGED------GDLKPASSLRLQGDS--KPPPAH 351
           APT P     T+T       P  PA    ++        L P +  +L   +  KP P  
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551

Query: 352 PLWRWQMGGPAVPEPP 367
           P    +   P  PE P
Sbjct: 552 P----EELAPTTPEEP 563



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 51/188 (27%), Positives = 71/188 (37%), Gaps = 14/188 (7%)

Query: 132 RSCAPPGRCPAPPHPRESTTSFASA---PPRPAPGLEPQRGPAASPPQEPSSRPPSPPAG 188
           +  AP  +  A P P+  TT+   A   P  P P    +  PA++ P+EP+         
Sbjct: 226 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPT 283

Query: 189 LSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAAPEAPA------ASPSTASPAPAAPGDLR 241
              EPA   T   P  P +PA      P P  P+ PA       +P+T   AP  P +  
Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 343

Query: 242 QEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP-PPRTAQP 300
                +    +            TP+  + P  P  K PA    K+    AP  P    P
Sbjct: 344 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP-APTTKEPAPTTPKEPAPTAPKKPAPTTP 402

Query: 301 RRPAPTLP 308
           + PAPT P
Sbjct: 403 KEPAPTTP 410



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 61/246 (24%), Positives = 90/246 (36%), Gaps = 40/246 (16%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASS-LGPGPGELA- 64
           P+   P +P+  P   TP++P   T +E +P   +  A   L +P  ++   P P ELA 
Sbjct: 584 PKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642

Query: 65  --ARSPVLR--GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEE 120
              + P        AP  P G AP   K     T +   P T  G        P   +E 
Sbjct: 643 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------TAPTTLKE- 695

Query: 121 EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPP-----RPAPGLEPQRGPAASPP 175
                          P    P  P P+E   +    P      +PAP    +  P  + P
Sbjct: 696 ---------------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP--TTP 738

Query: 176 QEPSSRPPSPPAGLSTEPAGPGTA--PRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP 232
           +EP+   P  PA  + E   P T+    P    +P  +  +P  + PE  A  +P     
Sbjct: 739 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 798

Query: 233 APAAPG 238
           +P  PG
Sbjct: 799 SPKEPG 804



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 75/316 (23%), Positives = 104/316 (32%), Gaps = 50/316 (15%)

Query: 6   PAP---RLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASSLGPGPG 61
           PAP   +   P +P+  P   TP++    T ++ +P     LA     KP  ++    P 
Sbjct: 499 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PE 553

Query: 62  ELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAA--CPRRGEE 119
           ELA  +P    P  P  P    P            P  P   A       A   P+    
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613

Query: 120 EEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPS 179
               G  P           + PAP     +TT   ++     P     +G A + P+EP+
Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673

Query: 180 SRPPSPPAGLSTEPAGPGT--APRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS--PAPA 235
              P  PA  + +   P T   P P  P +PA     P   AP       ST S  PAP 
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-----PKELAPTTTKGPTSTTSDKPAPT 728

Query: 236 APGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPP 295
            P +                          P+  + P     K PA    +      PPP
Sbjct: 729 TPKE------------------------TAPTTPKEPAPTTPKKPAPTTPE-----TPPP 759

Query: 296 RTAQPRRPAPTL-PTT 310
            T++   P  T  PTT
Sbjct: 760 TTSEVSTPTTTKEPTT 775



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 79/339 (23%), Positives = 109/339 (32%), Gaps = 45/339 (13%)

Query: 8   PRLAVPASPRGS-------PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPG 59
           P+   P +P+G+       P   TP+KP    +E +P   +        KP  ++  G  
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTPKGTA 665

Query: 60  PGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTG--RPG----VPNTAAGEDADVAAC 113
           P      +P      AP  P G AP  LK   APT   +P      P T  G  +  +  
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKGPTSTTSDK 724

Query: 114 PRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAAS 173
           P     +E     P     +  P    P  P     TTS  S P          + P  S
Sbjct: 725 PAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783

Query: 174 PPQEPSSRPPSPPAGLSTEPAGPGT----APRPFLP----GQPAEVDGNPPP----AAPE 221
            P+  +   P        EP  P T    A +P +      +  E D    P    AAP+
Sbjct: 784 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 843

Query: 222 -----APAASPSTASPAPAAPGDLR----QEHFDRLIRRSKLWCYAKGFA-----LDTPS 267
                A     +T S   A    +     Q+     I   K    A         + T  
Sbjct: 844 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 903

Query: 268 LRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPT 306
           +   PE   AK   R    K   P P   T  P++P  T
Sbjct: 904 IMNKPEET-AKPKDRATNSKATTPKPQKPTKAPKKPTST 941


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 87/323 (26%), Positives = 113/323 (34%), Gaps = 38/323 (11%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPGPGELAAR 66
           P+   P +P+  P   TP++P   T+E +P   +  A  A  KP  ++   P P      
Sbjct: 407 PKEPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465

Query: 67  SPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGF 126
           +P      +P  P   AP   K     T  P    T +         P   +E       
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----- 520

Query: 127 PHFGVRSCAPPGRCPAPPHPRE--STTSFASAP-----PRPAPGLEP-QRGPAASPPQEP 178
           P           + PAP  P+E   TT    AP     P P    EP    P  + P  P
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580

Query: 179 SSRPPSPPAGLS-TEPAGPG-TAPRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP-AP 234
               P+ P  L+ T P  P  T P    P  P E    P P  PE PA  +P  A+P  P
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE----PTPTTPEEPAPTTPKAAAPNTP 636

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP- 293
             P     +       +       K  A  TP   +G      K PA    KK   PAP 
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP---KGTAPTTLKEPAPTTPKK---PAPK 690

Query: 294 ---PPRTAQPR-----RPAPTLP 308
              P  T +P      +PAPT P
Sbjct: 691 ELAPTTTKEPTSTTCDKPAPTTP 713



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 78/331 (23%), Positives = 110/331 (33%), Gaps = 45/331 (13%)

Query: 2   ETLCPAPRLAVPASPRGS----PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLG 57
           ET    P L  P  P  +    P S TP++P   T + +P   +        +P  ++  
Sbjct: 295 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--------EPAPTTTK 346

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
             P      +P      AP  P   AP   K   APT     P T           P   
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPT 405

Query: 118 EEEEGGGGFPHFGV----RSCAPPGRCPAPPHPRESTTSFA-------------SAPPRP 160
             +E     P        +  AP  + PAP  P+E   +               + P  P
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465

Query: 161 APGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAA 219
           AP     + P+ + P+EP+          + EPA   T   P  P +P+      P P  
Sbjct: 466 AP--TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523

Query: 220 PEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKG 279
           P+ PA + +   PAP  P +           +       K  A  TP     P  P    
Sbjct: 524 PKEPAPT-TPKKPAPTTPKEPAP-----TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETA 576

Query: 280 PARGAAKKRRLPAPPPRTA--QPRRPAPTLP 308
           P      K+  P  P + A   P +PAPT P
Sbjct: 577 P---TTPKKLTPTTPEKLAPTTPEKPAPTTP 604



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 69/256 (26%), Positives = 94/256 (36%), Gaps = 40/256 (15%)

Query: 141 PAPPHPRE----STTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLST-EPAG 195
           PAP   +E    +T S  + P  PAP     + PA + P+EP+   P  P   +  EPA 
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 428

Query: 196 PGTAPRPFLPGQPA-EVDGNPPPAAPEAPA-------ASPSTASPAPAAPGDLRQEHFDR 247
               P P  P +PA      P P  P+ PA       A  +T  P+P  P +        
Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 488

Query: 248 LIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP----PPRTAQPRRP 303
               +K    A       P+  + P     K PA    K+   PAP     P    P+ P
Sbjct: 489 APTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE---PAPTTPKKPAPTTPKEP 543

Query: 304 APTLP----TTSTFSLLNCFPCPPALVVGED------GDLKPASSLRLQGDS--KPPPAH 351
           APT P     T+T       P  PA    ++        L P +  +L   +  KP P  
Sbjct: 544 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603

Query: 352 PLWRWQMGGPAVPEPP 367
           P    +   P  PE P
Sbjct: 604 P----EELAPTTPEEP 615



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 51/188 (27%), Positives = 71/188 (37%), Gaps = 14/188 (7%)

Query: 132 RSCAPPGRCPAPPHPRESTTSFASA---PPRPAPGLEPQRGPAASPPQEPSSRPPSPPAG 188
           +  AP  +  A P P+  TT+   A   P  P P    +  PA++ P+EP+         
Sbjct: 278 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPT 335

Query: 189 LSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAAPEAPA------ASPSTASPAPAAPGDLR 241
              EPA   T   P  P +PA      P P  P+ PA       +P+T   AP  P +  
Sbjct: 336 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 395

Query: 242 QEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP-PPRTAQP 300
                +    +            TP+  + P  P  K PA    K+    AP  P    P
Sbjct: 396 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP-APTTKEPAPTTPKEPAPTAPKKPAPTTP 454

Query: 301 RRPAPTLP 308
           + PAPT P
Sbjct: 455 KEPAPTTP 462



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 61/246 (24%), Positives = 90/246 (36%), Gaps = 40/246 (16%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASS-LGPGPGELA- 64
           P+   P +P+  P   TP++P   T +E +P   +  A   L +P  ++   P P ELA 
Sbjct: 636 PKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694

Query: 65  --ARSPVLR--GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEE 120
              + P        AP  P G AP   K     T +   P T  G        P   +E 
Sbjct: 695 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------TAPTTLKE- 747

Query: 121 EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPP-----RPAPGLEPQRGPAASPP 175
                          P    P  P P+E   +    P      +PAP    +  P  + P
Sbjct: 748 ---------------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP--TTP 790

Query: 176 QEPSSRPPSPPAGLSTEPAGPGTA--PRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP 232
           +EP+   P  PA  + E   P T+    P    +P  +  +P  + PE  A  +P     
Sbjct: 791 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 850

Query: 233 APAAPG 238
           +P  PG
Sbjct: 851 SPKEPG 856



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 75/316 (23%), Positives = 104/316 (32%), Gaps = 50/316 (15%)

Query: 6   PAP---RLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASSLGPGPG 61
           PAP   +   P +P+  P   TP++    T ++ +P     LA     KP  ++    P 
Sbjct: 551 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PE 605

Query: 62  ELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAA--CPRRGEE 119
           ELA  +P    P  P  P    P            P  P   A       A   P+    
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665

Query: 120 EEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPS 179
               G  P           + PAP     +TT   ++     P     +G A + P+EP+
Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725

Query: 180 SRPPSPPAGLSTEPAGPGT--APRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS--PAPA 235
              P  PA  + +   P T   P P  P +PA     P   AP       ST S  PAP 
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-----PKELAPTTTKGPTSTTSDKPAPT 780

Query: 236 APGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPP 295
            P +                          P+  + P     K PA    +      PPP
Sbjct: 781 TPKE------------------------TAPTTPKEPAPTTPKKPAPTTPE-----TPPP 811

Query: 296 RTAQPRRPAPTL-PTT 310
            T++   P  T  PTT
Sbjct: 812 TTSEVSTPTTTKEPTT 827



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 79/339 (23%), Positives = 109/339 (32%), Gaps = 45/339 (13%)

Query: 8   PRLAVPASPRGS-------PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPG 59
           P+   P +P+G+       P   TP+KP    +E +P   +        KP  ++  G  
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTPKGTA 717

Query: 60  PGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTG--RPG----VPNTAAGEDADVAAC 113
           P      +P      AP  P G AP  LK   APT   +P      P T  G  +  +  
Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKGPTSTTSDK 776

Query: 114 PRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAAS 173
           P     +E     P     +  P    P  P     TTS  S P          + P  S
Sbjct: 777 PAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 835

Query: 174 PPQEPSSRPPSPPAGLSTEPAGPGT----APRPFLP----GQPAEVDGNPPP----AAPE 221
            P+  +   P        EP  P T    A +P +      +  E D    P    AAP+
Sbjct: 836 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 895

Query: 222 -----APAASPSTASPAPAAPGDLR----QEHFDRLIRRSKLWCYAKGFA-----LDTPS 267
                A     +T S   A    +     Q+     I   K    A         + T  
Sbjct: 896 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 955

Query: 268 LRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPT 306
           +   PE   AK   R    K   P P   T  P++P  T
Sbjct: 956 IMNKPEET-AKPKDRATNSKATTPKPQKPTKAPKKPTST 993


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 87/323 (26%), Positives = 113/323 (34%), Gaps = 38/323 (11%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPGPGELAAR 66
           P+   P +P+  P   TP++P   T+E +P   +  A  A  KP  ++   P P      
Sbjct: 448 PKEPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506

Query: 67  SPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGF 126
           +P      +P  P   AP   K     T  P    T +         P   +E       
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA----- 561

Query: 127 PHFGVRSCAPPGRCPAPPHPRE--STTSFASAP-----PRPAPGLEP-QRGPAASPPQEP 178
           P           + PAP  P+E   TT    AP     P P    EP    P  + P  P
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621

Query: 179 SSRPPSPPAGLS-TEPAGPG-TAPRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP-AP 234
               P+ P  L+ T P  P  T P    P  P E    P P  PE PA  +P  A+P  P
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE----PTPTTPEEPAPTTPKAAAPNTP 677

Query: 235 AAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP- 293
             P     +       +       K  A  TP   +G      K PA    KK   PAP 
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP---KGTAPTTLKEPAPTTPKK---PAPK 731

Query: 294 ---PPRTAQPR-----RPAPTLP 308
              P  T +P      +PAPT P
Sbjct: 732 ELAPTTTKEPTSTTCDKPAPTTP 754



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 78/331 (23%), Positives = 110/331 (33%), Gaps = 45/331 (13%)

Query: 2   ETLCPAPRLAVPASPRGS----PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLG 57
           ET    P L  P  P  +    P S TP++P   T + +P   +        +P  ++  
Sbjct: 336 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK--------EPAPTTTK 387

Query: 58  PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRG 117
             P      +P      AP  P   AP   K   APT     P T           P   
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPT 446

Query: 118 EEEEGGGGFPHFGV----RSCAPPGRCPAPPHPRESTTSFA-------------SAPPRP 160
             +E     P        +  AP  + PAP  P+E   +               + P  P
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506

Query: 161 APGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAA 219
           AP     + P+ + P+EP+          + EPA   T   P  P +P+      P P  
Sbjct: 507 AP--TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564

Query: 220 PEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKG 279
           P+ PA + +   PAP  P +           +       K  A  TP     P  P    
Sbjct: 565 PKEPAPT-TPKKPAPTTPKEPAP-----TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETA 617

Query: 280 PARGAAKKRRLPAPPPRTA--QPRRPAPTLP 308
           P      K+  P  P + A   P +PAPT P
Sbjct: 618 P---TTPKKLTPTTPEKLAPTTPEKPAPTTP 645



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 69/256 (26%), Positives = 94/256 (36%), Gaps = 40/256 (15%)

Query: 141 PAPPHPRE----STTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLST-EPAG 195
           PAP   +E    +T S  + P  PAP     + PA + P+EP+   P  P   +  EPA 
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 469

Query: 196 PGTAPRPFLPGQPA-EVDGNPPPAAPEAPA-------ASPSTASPAPAAPGDLRQEHFDR 247
               P P  P +PA      P P  P+ PA       A  +T  P+P  P +        
Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 529

Query: 248 LIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP----PPRTAQPRRP 303
               +K    A       P+  + P     K PA    K+   PAP     P    P+ P
Sbjct: 530 APTTTKE--PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE---PAPTTPKKPAPTTPKEP 584

Query: 304 APTLP----TTSTFSLLNCFPCPPALVVGED------GDLKPASSLRLQGDS--KPPPAH 351
           APT P     T+T       P  PA    ++        L P +  +L   +  KP P  
Sbjct: 585 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644

Query: 352 PLWRWQMGGPAVPEPP 367
           P    +   P  PE P
Sbjct: 645 P----EELAPTTPEEP 656



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 51/188 (27%), Positives = 71/188 (37%), Gaps = 14/188 (7%)

Query: 132 RSCAPPGRCPAPPHPRESTTSFASA---PPRPAPGLEPQRGPAASPPQEPSSRPPSPPAG 188
           +  AP  +  A P P+  TT+   A   P  P P    +  PA++ P+EP+         
Sbjct: 319 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPKEPTPTTIKSAPT 376

Query: 189 LSTEPAGPGTAPRPFLPGQPA-EVDGNPPPAAPEAPA------ASPSTASPAPAAPGDLR 241
              EPA   T   P  P +PA      P P  P+ PA       +P+T   AP  P +  
Sbjct: 377 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 436

Query: 242 QEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP-PPRTAQP 300
                +    +            TP+  + P  P  K PA    K+    AP  P    P
Sbjct: 437 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP-APTTKEPAPTTPKEPAPTAPKKPAPTTP 495

Query: 301 RRPAPTLP 308
           + PAPT P
Sbjct: 496 KEPAPTTP 503



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 61/246 (24%), Positives = 90/246 (36%), Gaps = 40/246 (16%)

Query: 8   PRLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASS-LGPGPGELA- 64
           P+   P +P+  P   TP++P   T +E +P   +  A   L +P  ++   P P ELA 
Sbjct: 677 PKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735

Query: 65  --ARSPVLR--GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEE 120
              + P        AP  P G AP   K     T +   P T  G        P   +E 
Sbjct: 736 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------TAPTTLKE- 788

Query: 121 EGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPP-----RPAPGLEPQRGPAASPP 175
                          P    P  P P+E   +    P      +PAP    +  P  + P
Sbjct: 789 ---------------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP--TTP 831

Query: 176 QEPSSRPPSPPAGLSTEPAGPGTA--PRPFLPGQPAEVDGNPPPAAPEAPA-ASPSTASP 232
           +EP+   P  PA  + E   P T+    P    +P  +  +P  + PE  A  +P     
Sbjct: 832 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 891

Query: 233 APAAPG 238
           +P  PG
Sbjct: 892 SPKEPG 897



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 75/316 (23%), Positives = 104/316 (32%), Gaps = 50/316 (15%)

Query: 6   PAP---RLAVPASPRGSPCSPTPRKPCRGT-QEFSPLCLRALAFCALAKPRASSLGPGPG 61
           PAP   +   P +P+  P   TP++    T ++ +P     LA     KP  ++    P 
Sbjct: 592 PAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PE 646

Query: 62  ELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAA--CPRRGEE 119
           ELA  +P    P  P  P    P            P  P   A       A   P+    
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706

Query: 120 EEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPS 179
               G  P           + PAP     +TT   ++     P     +G A + P+EP+
Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766

Query: 180 SRPPSPPAGLSTEPAGPGT--APRPFLPGQPAEVDGNPPPAAPEAPAASPSTAS--PAPA 235
              P  PA  + +   P T   P P  P +PA     P   AP       ST S  PAP 
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-----PKELAPTTTKGPTSTTSDKPAPT 821

Query: 236 APGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPP 295
            P +                          P+  + P     K PA    +      PPP
Sbjct: 822 TPKE------------------------TAPTTPKEPAPTTPKKPAPTTPE-----TPPP 852

Query: 296 RTAQPRRPAPTL-PTT 310
            T++   P  T  PTT
Sbjct: 853 TTSEVSTPTTTKEPTT 868



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 79/339 (23%), Positives = 109/339 (32%), Gaps = 45/339 (13%)

Query: 8    PRLAVPASPRGS-------PCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASS-LGPG 59
            P+   P +P+G+       P   TP+KP    +E +P   +        KP  ++  G  
Sbjct: 701  PKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTPKGTA 758

Query: 60   PGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTG--RPG----VPNTAAGEDADVAAC 113
            P      +P      AP  P G AP  LK   APT   +P      P T  G  +  +  
Sbjct: 759  PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKGPTSTTSDK 817

Query: 114  PRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAAS 173
            P     +E     P     +  P    P  P     TTS  S P          + P  S
Sbjct: 818  PAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 876

Query: 174  PPQEPSSRPPSPPAGLSTEPAGPGT----APRPFLP----GQPAEVDGNPPP----AAPE 221
             P+  +   P        EP  P T    A +P +      +  E D    P    AAP+
Sbjct: 877  TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 936

Query: 222  -----APAASPSTASPAPAAPGDLR----QEHFDRLIRRSKLWCYAKGFA-----LDTPS 267
                 A     +T S   A    +     Q+     I   K    A         + T  
Sbjct: 937  MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 996

Query: 268  LRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPT 306
            +   PE   AK   R    K   P P   T  P++P  T
Sbjct: 997  IMNKPEET-AKPKDRATNSKATTPKPQKPTKAPKKPTST 1034


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 62/203 (30%), Positives = 78/203 (38%), Gaps = 27/203 (13%)

Query: 51  PRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRP-----GVPNTAAG 105
           P+     PGPG      P  +GP    RP       L  L  P G P       P +A  
Sbjct: 463 PQGGPPQPGPG------PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQ 516

Query: 106 EDADVAACPRRGEEEE-----GGGGFPHFGVRSCAP-PGRCPAPPHPRESTTSFASAPPR 159
           + A  AA P +G+  +     GG G P       +P P R   PP     T+    APP+
Sbjct: 517 QPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK 576

Query: 160 PA---PGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTA-PRPFLPGQPAEVDGNP 215
            +   PG + ++GP   PP        +  AG       P T  PRP  PG PA   G P
Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPG-PA---GRP 632

Query: 216 PPAAPEAPAASPSTASPAPAAPG 238
            P   + P  S     PA AA G
Sbjct: 633 KPQLAQKP--SQDVPPPATAAAG 653



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 60/211 (28%), Positives = 80/211 (37%), Gaps = 18/211 (8%)

Query: 112 ACPRRGEEEEGGGGFPHFGVRS--CAPPGRC----PAPPHPRESTTSFASAPPRPAPGLE 165
           A PR+ + +   G   H    S    P GR     PA P P +        PP+P PG +
Sbjct: 417 ALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGP-PAQQRPPPQGGPPQPGPGPQ 475

Query: 166 PQRGPAASPPQEPSSRPPS---PPAGLSTEPAGPGTAPRPFLPGQPAE--VDGNPPPAAP 220
            Q  P    P     +  S   PPAG       P     P  P   A     G    + P
Sbjct: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535

Query: 221 EAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTP---SLRRG-PERPP 276
            A       A+  PA+P   RQ    +  R++ +   A   A   P     R+G P++PP
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595

Query: 277 A-KGPARGAAKKRRLP-APPPRTAQPRRPAP 305
              GP R A++   +P   PP T QPR   P
Sbjct: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPSGP 626



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 78/306 (25%), Positives = 94/306 (30%), Gaps = 70/306 (22%)

Query: 49  AKPRASSLG--PGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGE 106
           A P   S G  P PG L       + P  P  P    P        P G P  P      
Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGP--PAQQRPP-------PQGGPPQPGPGPQR 476

Query: 107 DADVAAC--PRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPP------ 158
                    P +G++   G G P         P R P+P    +   S A+ P       
Sbjct: 477 QGPPLQQRPPPQGQQHLSGLGPP----AGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQ 532

Query: 159 -RPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPP 217
            RP  G  P   PAA PP  PS +  + P   + + +  G AP       P       PP
Sbjct: 533 SRPVAG-GPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP 591

Query: 218 AAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGP----- 272
             P  PA     AS A   P                               R GP     
Sbjct: 592 QKPPGPAGPTRQASQAGPVP-------------------------------RTGPPTTQQ 620

Query: 273 ERPPAKGPA----RGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCF----PCPPA 324
            RP   GPA       A+K     PPP TA    P P      + SL N F    P PP 
Sbjct: 621 PRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLNKSQSLTNAFNLPEPAPPR 679

Query: 325 LVVGED 330
             + +D
Sbjct: 680 PSLSQD 685



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 61/232 (26%), Positives = 79/232 (34%), Gaps = 32/232 (13%)

Query: 16  PRGSPCSPTP-----------RKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELA 64
           P+G P  P P           R P +G Q  S L   A +      P  +S    P   A
Sbjct: 463 PQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQA 522

Query: 65  ARSPVLRGPQA-PLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGG 123
           A     +G Q+ P+  G  AP   +   +P+     P   AG           G      
Sbjct: 523 APPTQGQGRQSRPVAGGPGAPPAARPPASPS-----PQRQAGPPQATRQTSVSGPAPPKA 577

Query: 124 GGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQR----GPAASP----P 175
            G P  G +   PP + P P  P    +     P    P  +  R    GPA  P     
Sbjct: 578 SGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLA 637

Query: 176 QEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDG-NPPPAAPEAPAAS 226
           Q+PS   P PPA      A  G  P P L    +  +  N P  AP  P+ S
Sbjct: 638 QKPSQDVP-PPA-----TAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLS 683



 Score = 35.4 bits (80), Expect = 0.085
 Identities = 42/163 (25%), Positives = 50/163 (30%), Gaps = 30/163 (18%)

Query: 12  VPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLR 71
           V   P   P +  P  P    Q   P   R  +    A P+AS   PG  +         
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595

Query: 72  GPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGV 131
           GP  P R    A         P  R G P T           PR       G   P    
Sbjct: 596 GPAGPTRQASQA--------GPVPRTGPPTTQQ---------PRPSGPGPAGRPKPQLAQ 638

Query: 132 R---SCAPPGRCPA--PPHP-----RESTTSF---ASAPPRPA 161
           +      PP    A  PPHP     +  T +F     APPRP+
Sbjct: 639 KPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPS 681



 Score = 29.3 bits (64), Expect = 6.1
 Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 14/63 (22%)

Query: 176 QEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPA 235
           Q P   PP P A       GPGTA      G               APAASP+  SP  +
Sbjct: 26  QRPQPPPPPPGAHSPGATPGPGTATAERSSG--------------VAPAASPAAPSPGSS 71

Query: 236 APG 238
             G
Sbjct: 72  GGG 74


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.136    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,087,267
Number of Sequences: 37866
Number of extensions: 2115145
Number of successful extensions: 39645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 870
Number of HSP's successfully gapped in prelim test: 2447
Number of HSP's that attempted gapping in prelim test: 12611
Number of HSP's gapped (non-prelim): 14617
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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