Guide to the Human Genome
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Search of human proteins with 194272161

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo
sapiens]
         (946 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapi...  1924   0.0  
gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens]    423   e-118
gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens]    417   e-116
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    56   1e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    56   1e-07
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]               52   3e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   8e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      49   2e-05
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          49   2e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      49   2e-05
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  49   2e-05
gi|239749196 PREDICTED: hypothetical protein XP_002346951 [Homo ...    48   5e-05
gi|239743276 PREDICTED: hypothetical protein XP_002342815 [Homo ...    48   5e-05
gi|239508959 PREDICTED: hypothetical protein [Homo sapiens]            48   5e-05
gi|91208420 bassoon protein [Homo sapiens]                             47   6e-05
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        45   2e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         45   2e-04
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         45   3e-04
gi|223633935 hypothetical protein LOC254427 [Homo sapiens]             45   4e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    44   5e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             44   5e-04
gi|22726201 inositol polyphosphate multikinase [Homo sapiens]          44   7e-04
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ...    44   7e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  43   0.001
gi|239749835 PREDICTED: hypothetical protein XP_002347183 [Homo ...    43   0.001
gi|239744125 PREDICTED: hypothetical protein XP_002343039 [Homo ...    43   0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        43   0.001
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         42   0.002
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    42   0.002
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     42   0.002

>gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo
           sapiens]
          Length = 946

 Score = 1924 bits (4984), Expect = 0.0
 Identities = 946/946 (100%), Positives = 946/946 (100%)

Query: 1   MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP 60
           MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
Sbjct: 1   MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP 60

Query: 61  AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS 120
           AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS
Sbjct: 61  AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS 120

Query: 121 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF 180
           PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
Sbjct: 121 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF 180

Query: 181 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR 240
           RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
Sbjct: 181 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR 240

Query: 241 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL 300
           AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
Sbjct: 241 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL 300

Query: 301 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER 360
           TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
Sbjct: 301 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER 360

Query: 361 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS 420
           GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS
Sbjct: 361 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS 420

Query: 421 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP 480
           VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
Sbjct: 421 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP 480

Query: 481 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD 540
           CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
Sbjct: 481 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD 540

Query: 541 ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS 600
           ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
Sbjct: 541 ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS 600

Query: 601 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF 660
           SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
Sbjct: 601 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF 660

Query: 661 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV 720
           VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
Sbjct: 661 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV 720

Query: 721 KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA 780
           KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA
Sbjct: 721 KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA 780

Query: 781 PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF 840
           PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF
Sbjct: 781 PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF 840

Query: 841 REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK 900
           REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK
Sbjct: 841 REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK 900

Query: 901 TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA 946
           TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA
Sbjct: 901 TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA 946


>gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens]
          Length = 461

 Score =  423 bits (1088), Expect = e-118
 Identities = 227/399 (56%), Positives = 276/399 (69%), Gaps = 7/399 (1%)

Query: 545 PELLPQDPDKPFLRKACSPSNIPAVIITDMGTQE-DGALEETQGSPRGNLPLRKLSSSSA 603
           P  LP+ P  P + +    +  P V  T  G  E +       GS     P R+LS+SS 
Sbjct: 67  PNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQP-RRLSTSSV 125

Query: 604 SSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMS 663
           SSTG SS  EDSE+D+ SD E     N       D  +      W+KI+ MV+  P +  
Sbjct: 126 SSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQ---KNHWQKIRTMVNL-PVISP 181

Query: 664 FKKKYPWIQLAGHAGSFKAAA-NGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKD 722
           FKK+Y W+QLAGH GSFKAA  +G ILK+  E E+ CL RLM D LR  VPA+HG V +D
Sbjct: 182 FKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERD 241

Query: 723 GERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPT 782
           GE Y Q+ DLL  FD PCV+DCKMG+RTYLEEELTKAR++P LRKDMY+KM+ VDPEAPT
Sbjct: 242 GESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPT 301

Query: 783 EEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFRE 842
           EEE AQRAVTKPRYMQWRE ISS+ TLGFRIEGIKK DG+ + DFK T++REQV   F E
Sbjct: 302 EEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEE 361

Query: 843 FTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTT 902
           F +G+  +L  Y +RL+ IR TLEVS FF+ HEVIGSSLLF+HD   +A VW+IDFGKTT
Sbjct: 362 FVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTT 421

Query: 903 PLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQ 941
           PLP+GQ L H  PW+EGNREDGYL GL+NL+ IL  +++
Sbjct: 422 PLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAE 460


>gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens]
          Length = 683

 Score =  417 bits (1071), Expect = e-116
 Identities = 219/432 (50%), Positives = 285/432 (65%), Gaps = 40/432 (9%)

Query: 528 SEGTWESQRQD-SDALPSPELLPQDPDKPFLRKA--------------CSP-SNIPAVII 571
           ++G+W     D S   P  + L  +P+   L +               CSP   +P +II
Sbjct: 273 TDGSWTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLII 332

Query: 572 TDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSS--SYEDSEEDISSDPERTLDP 629
           T    + +              P+   S     S GFSS  S+++SE+D+ +      DP
Sbjct: 333 TPETPEPEAQ------------PVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDP 380

Query: 630 NSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRIL 689
                          SK W+K+K ++ +SPFV+SF+K YPW+QL+GHAG+F+A  +GRIL
Sbjct: 381 EDR----------SGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRIL 430

Query: 690 KKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIR 749
           K+ C+ EQR L++LM D LRPFVPAY+G V++DG+ +NQM+DLLADF+ P +MDCKMG R
Sbjct: 431 KRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSR 490

Query: 750 TYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATL 809
           TYLEEEL KAR++P  RKDMY+KM+ VDP APT EE AQ AVTKPRYMQWRET+SST+TL
Sbjct: 491 TYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTL 550

Query: 810 GFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSP 869
           GFRIEGIKK DGT N +FKKT+  EQVT+   +F  G+H IL  Y   L+ +R  LE+SP
Sbjct: 551 GFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISP 610

Query: 870 FFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGL 929
           FFK HEV+GSSLLF+HD    AKVWMIDFGKT  LP+ QTL H +PW EGNREDGYL GL
Sbjct: 611 FFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGL 670

Query: 930 NNLVDILTEMSQ 941
           +N++ +L  ++Q
Sbjct: 671 DNMICLLQGLAQ 682


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 103/419 (24%), Positives = 138/419 (32%), Gaps = 59/419 (14%)

Query: 17   ANEMKSGGGPGPSGSETPPPP------------RRAVLSPGSVFSPGRGASFLFPPAESL 64
            A +    G PGP G    P P            R A   PG+   PG  A  + PP  + 
Sbjct: 854  AGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG-AAGRVGPPGSNG 912

Query: 65   SPEEPRSPG-GWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPG 123
            +P  P  PG   + G +     SG    +    +  P+     +G+      +G   PPG
Sbjct: 913  NPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 972

Query: 124  PEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSS 183
            P+    +  I             VG+     +     +  P S   G+  +P     R  
Sbjct: 973  PQGLAGQRGI-------------VGLPGQRGERGFPGLPGP-SGEPGKQGAPGASGDRGP 1018

Query: 184  SQPPGRVLVQGARSEERRTKSWGEQCP---ETSGTDSGRKGGPSLCSSQVKKGMPPLPGR 240
              P G   + G   E  R  S G   P   + +    G +G      +    G P  PG 
Sbjct: 1019 PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1078

Query: 241  AAPTGSE-------AQGPSAFVRMEKGIPASPR-CGSPTAMEIDKRGSPTPGTRSC---- 288
            A PTG +       AQGP     M    PA  R    P     DK  +  PG R      
Sbjct: 1079 AGPTGKQGDRGEAGAQGP-----MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1133

Query: 289  -LAPSLGLFGASLTMATEVAARVTS-TGPHRPQDLALTEPSGR--ARELEDLQPPEALVE 344
                  GL G       + A+     +GP  P       PSG+  A  +     P     
Sbjct: 1134 GFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP--GPVGPSGKDGANGIPGPIGPPGPRG 1191

Query: 345  RQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSA 403
            R G     ET PA   G P    PPG  G G       G G  E G  P +   + Q+A
Sbjct: 1192 RSG-----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1245



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 135/570 (23%), Positives = 177/570 (31%), Gaps = 132/570 (23%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFP--------------PAESLSPEEP 69
           G PG +G   PP P+ A   PG+   PG      +P                ES SP E 
Sbjct: 258 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 317

Query: 70  RSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSP-------- 121
            SPG    G R L    G          + P+ A   RG+  Q   AG   P        
Sbjct: 318 GSPGPM--GPRGLPGERGR---------TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 366

Query: 122 -PGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCP- 179
            PG   AK +               +           + A   P +  +  A+  +  P 
Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 426

Query: 180 ------FRSSSQPPGRVLVQGARSEERRTKS------WGEQCPETSGTDSGRKGGPSLCS 227
                 F     PPG     G    + +T         GEQ P+     +G +G P    
Sbjct: 427 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 486

Query: 228 SQVKKGMPPLPGRAAPTG--SEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGT 285
            + K+G    PG   P G   E   P       +G P       P       +G+P    
Sbjct: 487 EEGKRGARGEPGGVGPIGPPGERGAPG-----NRGFPGQDGLAGP-------KGAPGERG 534

Query: 286 RSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVER 345
            S LA   G  G                 P RP +  L    G      D  P       
Sbjct: 535 PSGLAGPKGANG----------------DPGRPGEPGLPGARGLTGRPGDAGP------- 571

Query: 346 QGQFLGSETSPAPERGGPRDGEPPGKMGKGYLP--CGMPG----SGEP-EVGKRPEETTV 398
           QG+ +G   +P  E G P    PPG  G    P   G PG    +GEP + G++      
Sbjct: 572 QGK-VGPSGAPG-EDGRP---GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 626

Query: 399 SVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQL----SDRVEGGSP------ 448
            ++     D  + +  P   A    E    GAP   G   L        EGG P      
Sbjct: 627 GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686

Query: 449 ----TLGLLG-----------GSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQC 493
                 GL+G           GSP AQ        G+   R L   P  D  K    P  
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQ--------GLQGPRGLPGTPGTDGPKGASGPAG 738

Query: 494 PPGDRVGVQPGNSRVWQGTMEKAGLAWTRG 523
           PPG +    P   +   G    AG+A  +G
Sbjct: 739 PPGAQ---GPPGLQGMPGERGAAGIAGPKG 765



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 137/530 (25%), Positives = 175/530 (33%), Gaps = 109/530 (20%)

Query: 17   ANEMKSGGGPGPSGSE---TPPPPRRAVLSPGSVFSPGRGAS--FLFPPAESLSPEEPRS 71
            A E    G PGPSG +    PP P      PG    PG   +   + P  E   P E  S
Sbjct: 650  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 709

Query: 72   PGG-WRSGRRRLNSSSGSGSGSSGSSVSSPSWA------------------GRLRGDRQQ 112
            PG     G R L  + G+      S  + P  A                     +GDR  
Sbjct: 710  PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769

Query: 113  VVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRA 172
            V   G    PG ++  R L            N + G       A S+  +     R G  
Sbjct: 770  VGEKGPEGAPG-KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER-GET 827

Query: 173  RSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKK 232
              P P  F   + PPG     GA+ E+                ++G+KG       Q   
Sbjct: 828  GPPGPAGF---AGPPGADGQPGAKGEQ---------------GEAGQKGDAGAPGPQGPS 869

Query: 233  GMPPLPGRAAPTGSE----AQGPSAFVRMEKGIP-ASPRCGSPTAMEIDKRGSPTPGTRS 287
            G P   G    TG +    AQGP        G P A+ R G P +       +  PG   
Sbjct: 870  GAPGPQGPTGVTGPKGARGAQGPPG----ATGFPGAAGRVGPPGS-------NGNPGPPG 918

Query: 288  CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347
               PS G  G          AR  S  P R  +  L  P+G         P E       
Sbjct: 919  PPGPS-GKDGPK-------GARGDSGPPGRAGEPGLQGPAG--------PPGEKGEPGDD 962

Query: 348  QFLGSETSPAPERGGPRDG--EPPGKMGKGYLPCGMPG-SGEPEVGKRPEETTVSVQSAE 404
               G+E  P P+    + G    PG+ G+   P G+PG SGEP  GK+          A 
Sbjct: 963  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP-GLPGPSGEP--GKQ------GAPGAS 1013

Query: 405  SSDSLSWSRLPRALASVGPEEARSGAPVG-------GGRWQLSDRVEGGSPTLGLLG--- 454
                      P  L     E  R G+P         G      DR E G+  +G  G   
Sbjct: 1014 GDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA--VGAPGAPG 1071

Query: 455  --GSPSAQPGTGNV----EAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDR 498
              GSP     TG      EAG   G M    P    A+ ++ PQ P GD+
Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAG-AQGPMGPSGPA--GARGIQGPQGPRGDK 1118



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 137/553 (24%), Positives = 182/553 (32%), Gaps = 95/553 (17%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
           G PGP+G +  P P       G+   PG G   + PP E  +P     PG     +  L 
Sbjct: 471 GEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPPGERGAPGNRGFPG-----QDGLA 524

Query: 84  SSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQV 143
              G+      S ++ P  A    GD       G    PG   A    R L     +   
Sbjct: 525 GPKGAPGERGPSGLAGPKGAN---GD------PGRPGEPGLPGA----RGLTGRPGDAGP 571

Query: 144 NQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQP--------PGRVLVQGA 195
             KVG   A  +        P+  R        P P  ++ +P        PG   ++G 
Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631

Query: 196 RSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTG-----SEAQG 250
             ++  T + G   P     + G +G P     Q   G P  PG     G      EA  
Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691

Query: 251 PSAF-VRMEKGIPASPRCGSPTAMEID-KRGSP-TPGTRSCLAPSLGLFGASLTMATEVA 307
           P     R E+G P     GSP A  +   RG P TPGT        G  GAS       A
Sbjct: 692 PGLVGPRGERGFPGER--GSPGAQGLQGPRGLPGTPGTD-------GPKGAS-----GPA 737

Query: 308 ARVTSTGPHRPQDL-------ALTEPSGRARELEDLQPPEALVERQGQFL-GSETSPAPE 359
               + GP   Q +        +  P G   ++ +  P  A  +  G+ L G    P P 
Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA 797

Query: 360 RGGPRDGE--PPGKMGKGYL--------------PCGMPG----SGEPEV-GKRPEETTV 398
                 GE  PPG  G                  P G  G     G+P   G++ E    
Sbjct: 798 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 857

Query: 399 SVQSAESSDSLSWSRLPRALASV-GPEEAR--SGAPVGGGRWQLSDRV-----EGGSPTL 450
               A      S +  P+    V GP+ AR   G P   G    + RV      G     
Sbjct: 858 GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 917

Query: 451 GLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQ 510
           G  G S    P     ++G P GR  EP         L+ P  PPG++           +
Sbjct: 918 GPPGPSGKDGPKGARGDSG-PPGRAGEP--------GLQGPAGPPGEKGEPGDDGPSGAE 968

Query: 511 GTMEKAGLAWTRG 523
           G     GLA  RG
Sbjct: 969 GPPGPQGLAGQRG 981



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 123/516 (23%), Positives = 154/516 (29%), Gaps = 92/516 (17%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPG-RGASFLFPPAESLSPEEPRSPGG--WRSGRR 80
            G  GP G+  P  P  A   PG    PG RGA+ +  P         + P G   + G R
Sbjct: 726  GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 785

Query: 81   RLNSSSG----SGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQR 136
             L    G    +G+      V  P  AG   G R      G   PPGP            
Sbjct: 786  GLTGPIGPPGPAGANGEKGEVGPPGPAGSA-GARGAPGERGETGPPGPAG------FAGP 838

Query: 137  ELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPR-----LGRARSPSPCPFRSSSQPPGRVL 191
               + Q   K    EA  +  + A   P+ P       G      P   R +  PPG   
Sbjct: 839  PGADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 897

Query: 192  VQGARSEERRTKSWGEQCPE----TSGTDS-----------GRKGGPSLCSSQVKKGMPP 236
              GA        S G   P      SG D            GR G P L       G   
Sbjct: 898  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957

Query: 237  LPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLF 296
             PG   P+G+E       +  ++GI   P        +  +RG P     S      G  
Sbjct: 958  EPGDDGPSGAEGPPGPQGLAGQRGIVGLPG-------QRGERGFPGLPGPSGEPGKQGAP 1010

Query: 297  GASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSP 356
            GAS              GP  P    LT P+G                      G E SP
Sbjct: 1011 GASGDRG--------PPGPVGPP--GLTGPAGEP--------------------GREGSP 1040

Query: 357  APERGGPRDGEPPGKMGKGYL----------PCGMPGSGEPEVGKRPEETTVSVQSAESS 406
              +    RDG    K  +G            P G PG   P  GK+ +      Q     
Sbjct: 1041 GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP-TGKQGDRGEAGAQGPMGP 1099

Query: 407  DSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNV 466
               + +R        GP+  R      G   +   +   G   L  L G P      G  
Sbjct: 1100 SGPAGAR-----GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1154

Query: 467  EAGIPSGRMLEPLPCWDAAKD----LKEPQCPPGDR 498
                PSG    P P   + KD    +  P  PPG R
Sbjct: 1155 GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1190



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 116/531 (21%), Positives = 150/531 (28%), Gaps = 98/531 (18%)

Query: 22  SGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRR 81
           + G PGP G +  P   + ++ P              PP     P+ P    G R  R  
Sbjct: 96  ASGQPGPKGQKGEPGDIKDIVGPKG------------PPG----PQGPAGEQGPRGDRGD 139

Query: 82  LNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNV 141
                  G         +P   G            G   PPGP               N 
Sbjct: 140 KGEKGAPGPRGRDGEPGTPGNPG----------PPGPPGPPGPPGLGG----------NF 179

Query: 142 QVNQKVGMFEAHIQAQSSAIQAPRSPR-----LGRARSPSPCPFRSSSQPPGRVLVQGAR 196
                 G  E    AQ   +Q P  P       G A +P P  F+ +   PG   V G  
Sbjct: 180 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 239

Query: 197 S---------------EERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPL---- 237
                           E  +    GE+ P       G  G P L   +  +G P L    
Sbjct: 240 GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 299

Query: 238 -----PGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPS 292
                PG    +GS  +  S      +G+P       P      +     PG      P 
Sbjct: 300 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 359

Query: 293 LGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQP--------PEALVE 344
               G     A         TG   P+      P G         P         + +  
Sbjct: 360 GPAGGPGFPGAPGAKGEAGPTGARGPE--GAQGPRGEPGTPGSPGPAGASGNPGTDGIPG 417

Query: 345 RQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPG-SGEP-------EVGKRPEET 396
            +G       + AP   GPR   PPG  G    P G  G +GEP       E G + E  
Sbjct: 418 AKGSAGAPGIAGAPGFPGPRG--PPGPQG-ATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474

Query: 397 TVSVQSAESSDSLSWSR----LPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGL 452
               Q A         R     P  +  +GP   R GAP G   +   D + G     G 
Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER-GAP-GNRGFPGQDGLAGPKGAPGE 532

Query: 453 LGGSPSAQPGTGN------VEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGD 497
            G S  A P   N       E G+P  R L   P     +    P   PG+
Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 103/419 (24%), Positives = 138/419 (32%), Gaps = 59/419 (14%)

Query: 17   ANEMKSGGGPGPSGSETPPPP------------RRAVLSPGSVFSPGRGASFLFPPAESL 64
            A +    G PGP G    P P            R A   PG+   PG  A  + PP  + 
Sbjct: 785  AGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG-AAGRVGPPGSNG 843

Query: 65   SPEEPRSPG-GWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPG 123
            +P  P  PG   + G +     SG    +    +  P+     +G+      +G   PPG
Sbjct: 844  NPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 903

Query: 124  PEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSS 183
            P+    +  I             VG+     +     +  P S   G+  +P     R  
Sbjct: 904  PQGLAGQRGI-------------VGLPGQRGERGFPGLPGP-SGEPGKQGAPGASGDRGP 949

Query: 184  SQPPGRVLVQGARSEERRTKSWGEQCP---ETSGTDSGRKGGPSLCSSQVKKGMPPLPGR 240
              P G   + G   E  R  S G   P   + +    G +G      +    G P  PG 
Sbjct: 950  PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1009

Query: 241  AAPTGSE-------AQGPSAFVRMEKGIPASPR-CGSPTAMEIDKRGSPTPGTRSC---- 288
            A PTG +       AQGP     M    PA  R    P     DK  +  PG R      
Sbjct: 1010 AGPTGKQGDRGEAGAQGP-----MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1064

Query: 289  -LAPSLGLFGASLTMATEVAARVTS-TGPHRPQDLALTEPSGR--ARELEDLQPPEALVE 344
                  GL G       + A+     +GP  P       PSG+  A  +     P     
Sbjct: 1065 GFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP--GPVGPSGKDGANGIPGPIGPPGPRG 1122

Query: 345  RQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSA 403
            R G     ET PA   G P    PPG  G G       G G  E G  P +   + Q+A
Sbjct: 1123 RSG-----ETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1176



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 135/570 (23%), Positives = 177/570 (31%), Gaps = 132/570 (23%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFP--------------PAESLSPEEP 69
           G PG +G   PP P+ A   PG+   PG      +P                ES SP E 
Sbjct: 189 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 248

Query: 70  RSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSP-------- 121
            SPG    G R L    G          + P+ A   RG+  Q   AG   P        
Sbjct: 249 GSPGPM--GPRGLPGERGR---------TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 297

Query: 122 -PGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCP- 179
            PG   AK +               +           + A   P +  +  A+  +  P 
Sbjct: 298 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 357

Query: 180 ------FRSSSQPPGRVLVQGARSEERRTKS------WGEQCPETSGTDSGRKGGPSLCS 227
                 F     PPG     G    + +T         GEQ P+     +G +G P    
Sbjct: 358 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 417

Query: 228 SQVKKGMPPLPGRAAPTG--SEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGT 285
            + K+G    PG   P G   E   P       +G P       P       +G+P    
Sbjct: 418 EEGKRGARGEPGGVGPIGPPGERGAPG-----NRGFPGQDGLAGP-------KGAPGERG 465

Query: 286 RSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVER 345
            S LA   G  G                 P RP +  L    G      D  P       
Sbjct: 466 PSGLAGPKGANG----------------DPGRPGEPGLPGARGLTGRPGDAGP------- 502

Query: 346 QGQFLGSETSPAPERGGPRDGEPPGKMGKGYLP--CGMPG----SGEP-EVGKRPEETTV 398
           QG+ +G   +P  E G P    PPG  G    P   G PG    +GEP + G++      
Sbjct: 503 QGK-VGPSGAPG-EDGRP---GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 557

Query: 399 SVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQL----SDRVEGGSP------ 448
            ++     D  + +  P   A    E    GAP   G   L        EGG P      
Sbjct: 558 GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 617

Query: 449 ----TLGLLG-----------GSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQC 493
                 GL+G           GSP AQ        G+   R L   P  D  K    P  
Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQ--------GLQGPRGLPGTPGTDGPKGASGPAG 669

Query: 494 PPGDRVGVQPGNSRVWQGTMEKAGLAWTRG 523
           PPG +    P   +   G    AG+A  +G
Sbjct: 670 PPGAQ---GPPGLQGMPGERGAAGIAGPKG 696



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 137/530 (25%), Positives = 175/530 (33%), Gaps = 109/530 (20%)

Query: 17   ANEMKSGGGPGPSGSE---TPPPPRRAVLSPGSVFSPGRGAS--FLFPPAESLSPEEPRS 71
            A E    G PGPSG +    PP P      PG    PG   +   + P  E   P E  S
Sbjct: 581  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640

Query: 72   PGG-WRSGRRRLNSSSGSGSGSSGSSVSSPSWA------------------GRLRGDRQQ 112
            PG     G R L  + G+      S  + P  A                     +GDR  
Sbjct: 641  PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700

Query: 113  VVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRA 172
            V   G    PG ++  R L            N + G       A S+  +     R G  
Sbjct: 701  VGEKGPEGAPG-KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER-GET 758

Query: 173  RSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKK 232
              P P  F   + PPG     GA+ E+                ++G+KG       Q   
Sbjct: 759  GPPGPAGF---AGPPGADGQPGAKGEQ---------------GEAGQKGDAGAPGPQGPS 800

Query: 233  GMPPLPGRAAPTGSE----AQGPSAFVRMEKGIP-ASPRCGSPTAMEIDKRGSPTPGTRS 287
            G P   G    TG +    AQGP        G P A+ R G P +       +  PG   
Sbjct: 801  GAPGPQGPTGVTGPKGARGAQGPPG----ATGFPGAAGRVGPPGS-------NGNPGPPG 849

Query: 288  CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347
               PS G  G          AR  S  P R  +  L  P+G         P E       
Sbjct: 850  PPGPS-GKDGPK-------GARGDSGPPGRAGEPGLQGPAG--------PPGEKGEPGDD 893

Query: 348  QFLGSETSPAPERGGPRDG--EPPGKMGKGYLPCGMPG-SGEPEVGKRPEETTVSVQSAE 404
               G+E  P P+    + G    PG+ G+   P G+PG SGEP  GK+          A 
Sbjct: 894  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP-GLPGPSGEP--GKQ------GAPGAS 944

Query: 405  SSDSLSWSRLPRALASVGPEEARSGAPVG-------GGRWQLSDRVEGGSPTLGLLG--- 454
                      P  L     E  R G+P         G      DR E G+  +G  G   
Sbjct: 945  GDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA--VGAPGAPG 1002

Query: 455  --GSPSAQPGTGNV----EAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDR 498
              GSP     TG      EAG   G M    P    A+ ++ PQ P GD+
Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAG-AQGPMGPSGPA--GARGIQGPQGPRGDK 1049



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 137/553 (24%), Positives = 182/553 (32%), Gaps = 95/553 (17%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
           G PGP+G +  P P       G+   PG G   + PP E  +P     PG     +  L 
Sbjct: 402 GEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPPGERGAPGNRGFPG-----QDGLA 455

Query: 84  SSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQV 143
              G+      S ++ P  A    GD       G    PG   A    R L     +   
Sbjct: 456 GPKGAPGERGPSGLAGPKGAN---GD------PGRPGEPGLPGA----RGLTGRPGDAGP 502

Query: 144 NQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQP--------PGRVLVQGA 195
             KVG   A  +        P+  R        P P  ++ +P        PG   ++G 
Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562

Query: 196 RSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTG-----SEAQG 250
             ++  T + G   P     + G +G P     Q   G P  PG     G      EA  
Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622

Query: 251 PSAF-VRMEKGIPASPRCGSPTAMEID-KRGSP-TPGTRSCLAPSLGLFGASLTMATEVA 307
           P     R E+G P     GSP A  +   RG P TPGT        G  GAS       A
Sbjct: 623 PGLVGPRGERGFPGER--GSPGAQGLQGPRGLPGTPGTD-------GPKGAS-----GPA 668

Query: 308 ARVTSTGPHRPQDL-------ALTEPSGRARELEDLQPPEALVERQGQFL-GSETSPAPE 359
               + GP   Q +        +  P G   ++ +  P  A  +  G+ L G    P P 
Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA 728

Query: 360 RGGPRDGE--PPGKMGKGYL--------------PCGMPG----SGEPEV-GKRPEETTV 398
                 GE  PPG  G                  P G  G     G+P   G++ E    
Sbjct: 729 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 788

Query: 399 SVQSAESSDSLSWSRLPRALASV-GPEEAR--SGAPVGGGRWQLSDRV-----EGGSPTL 450
               A      S +  P+    V GP+ AR   G P   G    + RV      G     
Sbjct: 789 GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 848

Query: 451 GLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQ 510
           G  G S    P     ++G P GR  EP         L+ P  PPG++           +
Sbjct: 849 GPPGPSGKDGPKGARGDSG-PPGRAGEP--------GLQGPAGPPGEKGEPGDDGPSGAE 899

Query: 511 GTMEKAGLAWTRG 523
           G     GLA  RG
Sbjct: 900 GPPGPQGLAGQRG 912



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 123/516 (23%), Positives = 154/516 (29%), Gaps = 92/516 (17%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPG-RGASFLFPPAESLSPEEPRSPGG--WRSGRR 80
            G  GP G+  P  P  A   PG    PG RGA+ +  P         + P G   + G R
Sbjct: 657  GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 716

Query: 81   RLNSSSG----SGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQR 136
             L    G    +G+      V  P  AG   G R      G   PPGP            
Sbjct: 717  GLTGPIGPPGPAGANGEKGEVGPPGPAGSA-GARGAPGERGETGPPGPAG------FAGP 769

Query: 137  ELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPR-----LGRARSPSPCPFRSSSQPPGRVL 191
               + Q   K    EA  +  + A   P+ P       G      P   R +  PPG   
Sbjct: 770  PGADGQPGAKGEQGEAGQKGDAGA-PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 828

Query: 192  VQGARSEERRTKSWGEQCPE----TSGTDS-----------GRKGGPSLCSSQVKKGMPP 236
              GA        S G   P      SG D            GR G P L       G   
Sbjct: 829  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888

Query: 237  LPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLF 296
             PG   P+G+E       +  ++GI   P        +  +RG P     S      G  
Sbjct: 889  EPGDDGPSGAEGPPGPQGLAGQRGIVGLPG-------QRGERGFPGLPGPSGEPGKQGAP 941

Query: 297  GASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSP 356
            GAS              GP  P    LT P+G                      G E SP
Sbjct: 942  GASGDRG--------PPGPVGPP--GLTGPAGEP--------------------GREGSP 971

Query: 357  APERGGPRDGEPPGKMGKGYL----------PCGMPGSGEPEVGKRPEETTVSVQSAESS 406
              +    RDG    K  +G            P G PG   P  GK+ +      Q     
Sbjct: 972  GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP-TGKQGDRGEAGAQGPMGP 1030

Query: 407  DSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNV 466
               + +R        GP+  R      G   +   +   G   L  L G P      G  
Sbjct: 1031 SGPAGAR-----GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGAS 1085

Query: 467  EAGIPSGRMLEPLPCWDAAKD----LKEPQCPPGDR 498
                PSG    P P   + KD    +  P  PPG R
Sbjct: 1086 GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1121



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 115/527 (21%), Positives = 148/527 (28%), Gaps = 98/527 (18%)

Query: 26  PGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSS 85
           PGP G +  P   + ++ P              PP     P+ P    G R  R      
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKG------------PPG----PQGPAGEQGPRGDRGDKGEK 74

Query: 86  SGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQ 145
              G         +P   G            G   PPGP               N     
Sbjct: 75  GAPGPRGRDGEPGTPGNPG----------PPGPPGPPGPPGLGG----------NFAAQM 114

Query: 146 KVGMFEAHIQAQSSAIQAPRSPR-----LGRARSPSPCPFRSSSQPPGRVLVQGARS--- 197
             G  E    AQ   +Q P  P       G A +P P  F+ +   PG   V G      
Sbjct: 115 AGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRG 174

Query: 198 ------------EERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPL-------- 237
                       E  +    GE+ P       G  G P L   +  +G P L        
Sbjct: 175 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234

Query: 238 -PGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLF 296
            PG    +GS  +  S      +G+P       P      +     PG      P     
Sbjct: 235 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294

Query: 297 GASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQP--------PEALVERQGQ 348
           G     A         TG   P+      P G         P         + +   +G 
Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPE--GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352

Query: 349 FLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPG-SGEP-------EVGKRPEETTVSV 400
                 + AP   GPR   PPG  G    P G  G +GEP       E G + E      
Sbjct: 353 AGAPGIAGAPGFPGPRG--PPGPQG-ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 409

Query: 401 QSAESSDSLSWSR----LPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGS 456
           Q A         R     P  +  +GP   R GAP G   +   D + G     G  G S
Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGER-GAP-GNRGFPGQDGLAGPKGAPGERGPS 467

Query: 457 PSAQPGTGN------VEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGD 497
             A P   N       E G+P  R L   P     +    P   PG+
Sbjct: 468 GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 111/448 (24%), Positives = 154/448 (34%), Gaps = 103/448 (22%)

Query: 5   CYALNSLVIMNSANEMKSGGGPGPSGSETPPP-PRRAVLSPGSVFSPGRGASFLFPPAES 63
           C+++ S+  +       SGG    S +  PP  PRR   +  S+  PG GA    PP++ 
Sbjct: 85  CHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAET--PPSKK 142

Query: 64  LSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPG 123
              ++P +P G  S R+                   P    R   + Q  V+     PPG
Sbjct: 143 AGSQKP-TPEGRESSRK------------------VPPQKPRRSPNTQLSVSFDESCPPG 183

Query: 124 PEEAKRKLRILQRELQNVQV--NQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFR 181
           P      L  LQR  +  +V  +  VG  E  +  +          R G   +  P    
Sbjct: 184 PSPRGGNLP-LQRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGLAGPPLGGG 242

Query: 182 SSSQPPGRVLVQGARSEERRTKSWGEQC----PETSGTDSGRKGGPSLCSSQVKKGMPPL 237
             + P G      A S+   +++  E+     PE +G   GR  GP           PPL
Sbjct: 243 GPTPPAG------ADSDSEESEAIYEEMKYPLPEEAG--EGRANGP-----------PPL 283

Query: 238 PGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPT----------------------AMEI 275
              + P    A  P A  R    +P S R G+PT                      A   
Sbjct: 284 TATSPPQQPHALPPHAHRRPASALP-SRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQ 342

Query: 276 DKRGSPTPGTRSCLAPSL--GLFGASLTMATEVAARVTSTGPHRPQ----DLALTEPSGR 329
            K  S TPG      P L      A  T A +V AR   T P  P     +L L  PSGR
Sbjct: 343 AKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGR 402

Query: 330 ARELEDLQPPEALVERQG--QFLGSETSPAPERGGPRDGEP-PGKMGKG----------- 375
           AR      PP+   + +G  +   S +   P+  G     P P  +  G           
Sbjct: 403 ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTM 462

Query: 376 -----------YLPCGMP-GSGEPEVGK 391
                       LP G P G+GEP+  K
Sbjct: 463 VYSAVKVTTHSVLPAGPPLGAGEPKTEK 490


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 106/429 (24%), Positives = 154/429 (35%), Gaps = 54/429 (12%)

Query: 26   PGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSS 85
            P P G    PPP+ A  +P +     +G   L  P+   +P  P +      G     S 
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGG--LATPSPKGAPTTPAATPPSPKGGLATPSP 1214

Query: 86   SGS--------GSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRE 137
             G+         S   G +  SP  A             G  +PP P+ A          
Sbjct: 1215 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP-PKGAPTPPAATPPS 1273

Query: 138  LQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSP---SPCPFR----SSSQPPGRV 190
            L+             H  A + A+  P SP+ G A SP   +P P      S    PG  
Sbjct: 1274 LKGGLAT------PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327

Query: 191  LVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQG 250
              +GA +    T    +  P    T    KGGP+  SS  K+G  P P  A P  S   G
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS--KEG--PTPPAATP--SHKGG 1381

Query: 251  PSAFVRMEKGIPASPR-CGSPTAMEI----DKRGSPTPGTRSCLA-PSLG-LFGASLTMA 303
            P+      K  PA P   G PT+  +     K+   TP TR   A PS G L   ++T  
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441

Query: 304  TEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGP 363
            +   A  TS     P+    T  S     L  + PP        + + + +SP       
Sbjct: 1442 SLKKAPATSA----PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP------K 1491

Query: 364  RDGEPPGKMGKGYLPCGMPGS-----GEPEVGKRPEETTVSVQSAESSDSLS--WSRLPR 416
            +    P  MG   LP  +P S       P   + P   T ++ S ++  +L+   + +P 
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551

Query: 417  ALASVGPEE 425
            A+    P++
Sbjct: 1552 AMTVPSPKK 1560



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 109/501 (21%), Positives = 155/501 (30%), Gaps = 105/501 (20%)

Query: 15   NSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSP-------- 66
            NS +   S   P  + S TPP P+ A  +P +V +P        PP E+ +P        
Sbjct: 839  NSLSFQGSKDSPATTHSPTPPSPKGAP-TPSAV-TPLSPKGVTLPPKETPTPSVVNLPFP 896

Query: 67   -EEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPE 125
             E P +P   ++    + SSS   + ++ +    P+ +   +G      A       GP 
Sbjct: 897  KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTPPAATPPSPKGGPA 955

Query: 126  EAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRAR-SPSPCPFRSSS 184
                K                         A +     P SP+ G A  SP   P   ++
Sbjct: 956  TPSPKW------------------------APTPPAATPPSPKGGPATPSPKGAPTPPAA 991

Query: 185  QPPGRVLVQGARSEERRTKSWGEQCPETSG-------TDSGRKGGPSLCSSQVKKGMPPL 237
             PP              +   G   P   G       T    KG P+          PP 
Sbjct: 992  TPP--------------SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037

Query: 238  PGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFG 297
                +P GS A  P     + KG P +P    P+     K G  TP  +    P      
Sbjct: 1038 ATPPSPKGSPAATP-----LPKGAPTTPAATLPSP----KGGPATPSLKGAPTPP----- 1083

Query: 298  ASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPA 357
             + T  +      T +    P   A T PS +        PP           G+ T+PA
Sbjct: 1084 -AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT---PPHK---------GAPTTPA 1130

Query: 358  PERGGPRDG--EPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLP 415
                 P+ G   PP K G    P   P S +  +   P +   +  +A            
Sbjct: 1131 ATPPSPKGGLATPPPK-GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG----- 1184

Query: 416  RALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRM 475
              LA+  P+    GAP        +      SP  GL   SP   P T       P G +
Sbjct: 1185 -GLATPSPK----GAPT-------TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232

Query: 476  LEPLPCWDAAKDLKEPQCPPG 496
              P P          P  P G
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKG 1253



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 102/484 (21%), Positives = 158/484 (32%), Gaps = 98/484 (20%)

Query: 26   PGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSS 85
            P P G     PP+ A   P +     +G+    PP  + +P     P    +      + 
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 86   SGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQ 145
            S  G  ++ SS   P+        +        ++PP P+                    
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHK----GGPAMTPPSPK-------------------- 1390

Query: 146  KVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSW 205
                       +  AI +P+    G   SP+  P      P   V  +GA      T S 
Sbjct: 1391 -----------RGPAIPSPK----GDPTSPAVIPLSPKKAPATPVTREGA-----ATPSK 1430

Query: 206  GEQCP--------ETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPS--AFV 255
            G+  P        + +   S  KGGP+  SS   KG P LP    P+  E   P   A  
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSS---KGDPTLPAVTPPSPKEPPAPKQVATS 1487

Query: 256  RMEKGIPASPR-CGSPTAMEI----DKRGSPTPGTR----------------SCLAPSLG 294
               K  PA+P   G+PT   +     K    TP +R                + LAP   
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547

Query: 295  LFGASLTMAT-----------EVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEAL- 342
            L   ++T+ +           E  A  +S     P  +  +   G     E L PP    
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607

Query: 343  -VERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQ 401
               ++     + T P+PE+G       P   G    P   P S + +    P   T  + 
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKG----PATPAPKGTPTSPPVTPSSLK-DSPTSPASVTCKMG 1662

Query: 402  SA--ESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSA 459
            +   ++S  L   + P AL  V    A    P+     +   + +  S T   +   PSA
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722

Query: 460  QPGT 463
            + G+
Sbjct: 1723 KNGS 1726



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 96/465 (20%), Positives = 143/465 (30%), Gaps = 57/465 (12%)

Query: 59   PPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSS------PSWAGRLRGDRQQ 112
            P   S+SP+  R P       ++ ++   +  G+  S VS       P  +   +G +  
Sbjct: 796  PLGVSVSPQTKRPP------TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849

Query: 113  VVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKV----GMFEAHIQAQSSAIQAPRSPR 168
                 + +PP P+ A     +     + V +  K      +       +  A  AP+   
Sbjct: 850  PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 169  LGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSS 228
                 S SP   R++  P G   +  + S +      G   P  + T    KGGP+  S 
Sbjct: 910  ALSMTSSSPKKARATPAPKG---IPASPSPK------GAPTPPAA-TPPSPKGGPATPSP 959

Query: 229  Q----VKKGMPPLP--GRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPT 282
            +         PP P  G A P+   A  P A        P SP+ G  T      +G+PT
Sbjct: 960  KWAPTPPAATPPSPKGGPATPSPKGAPTPPA------ATPPSPKGGPATP---SPKGAPT 1010

Query: 283  PGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEAL 342
            P   +  +P                   T   P +    A   P G         P    
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSP-KGSPAATPLPKGAPTTPAATLPSPKG 1069

Query: 343  VERQGQFLGSETSPAPERGGPRDGEP-PGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQ 401
                    G+ T PA     P+ G   P   G    P   P S +  +   P +   +  
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 402  SAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTL----------G 451
            +A           P    +     A   +P GG    L+     G+PT           G
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGG----LATPPPKGAPTTPAATPPSPKGG 1185

Query: 452  LLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPG 496
            L   SP   P T       P G +  P P          P  P G
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 122/504 (24%), Positives = 158/504 (31%), Gaps = 91/504 (18%)

Query: 19   EMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEE-----PRSPG 73
            E  + G PGP G      P+ A  SPG     G     + PP  + +P +     P  P 
Sbjct: 732  ERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP-IGPPGPAGAPGDKGESGPSGPA 790

Query: 74   GWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGR--LRGDRQQVVAAGTLSPPGPEEAKRKL 131
            G    R         G          P   G+   +G+     A G   PPGP       
Sbjct: 791  GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP------- 843

Query: 132  RILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVL 191
                                       +    P  P +G   +P     R S+ PPG   
Sbjct: 844  ---------------------------AGPAGPPGP-IGNVGAPGAKGARGSAGPPGATG 875

Query: 192  VQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGP 251
              GA          G   P      +G++GG      + + G    PG   P G    GP
Sbjct: 876  FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK---GPRGETGPAGRPGEVGPPG--PPGP 930

Query: 252  SAFVRMEKGIPASPRCGSPTAMEIDKRGSP-TPGTRSCLAPSLGLFGASLTMATEVAARV 310
            +     EKG   SP    P        G+P TPG +  +A   G+ G    +  +   R 
Sbjct: 931  AG----EKG---SPGADGPA-------GAPGTPGPQG-IAGQRGVVG----LPGQRGERG 971

Query: 311  TSTGPHRPQDLALTEPSGRARELEDLQP--PEALVERQGQFLGSETSPAPERGGPRDGEP 368
                P    +     PSG + E     P  P  L    G+  G E +P  E    RDG P
Sbjct: 972  FPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE-SGREGAPGAEGSPGRDGSP 1030

Query: 369  PGKMGKGYL-PCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEAR 427
              K  +G   P G PG+        P      V  A  S     +        VGP  AR
Sbjct: 1031 GAKGDRGETGPAGPPGAPGAPGAPGP------VGPAGKSGDRGETGPAGPAGPVGPVGAR 1084

Query: 428  SGAPVGGGRWQLSDRVEGGSPTL-------GLLG--GSPSAQPGTGNVEAGIPSGRMLEP 478
              A   G R    +  E G   +       GL G  G P +    G   A  P+G    P
Sbjct: 1085 GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPP 1144

Query: 479  ----LPCWDAAKDLKEPQCPPGDR 498
                 P  D    L  P  PPG R
Sbjct: 1145 GSAGAPGKDGLNGLPGPIGPPGPR 1168



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 128/530 (24%), Positives = 166/530 (31%), Gaps = 108/530 (20%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPG----RGASFLFPPAESLSPEEPRSPGGWRSGR 79
           G PG  G   PP P+ A   PG+   PG    RG S L        P  P+   G     
Sbjct: 236 GKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGEN 295

Query: 80  RRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQ 139
                    G         +P  AG  RG+     AAG   P GP               
Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGA-RGNDGATGAAGPPGPTGPAGPPG---------- 344

Query: 140 NVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEE 199
                     F   + A+  A   P+ PR     S  P   R    PPG     G     
Sbjct: 345 ----------FPGAVGAKGEA--GPQGPR----GSEGPQGVRGEPGPPGPAGAAGPAGNP 388

Query: 200 RRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEK 259
                 G +         G  G P +       G P  PG   P+G +  G     +   
Sbjct: 389 GADGQPGAK---------GANGAPGIA------GAPGFPGARGPSGPQGPGGPPGPKGNS 433

Query: 260 GIPASPRCGSPT-----------------AMEIDKRGS-PTPGTRSCLAP--------SL 293
           G P +P     T                 A E  KRG+   PG      P        S 
Sbjct: 434 GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSR 493

Query: 294 GLFGASLTMATE-VAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGS 352
           G  GA      +  A    S GP  P+      P    R      P EA +       GS
Sbjct: 494 GFPGADGVAGPKGPAGERGSPGPAGPKG----SPGEAGR------PGEAGLPGAKGLTGS 543

Query: 353 ETSPAPE-RGGP-----RDGE-----PPGKMGKGYLPCGMPG----SGEP-EVGKRPEET 396
             SP P+ + GP     +DG      PPG  G+  +  G PG    +GEP + G+R    
Sbjct: 544 PGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGV-MGFPGPKGAAGEPGKAGERGVPG 602

Query: 397 TVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGS 456
                     D  + ++ P   A    E    G P G   +Q    + G +   G   G 
Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG-PAGSPGFQ---GLPGPAGPPG-EAGK 657

Query: 457 PSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDR-VGVQPGN 505
           P  Q   G++ A  PSG   E    +   + ++ P  P G R     PGN
Sbjct: 658 PGEQGVPGDLGAPGPSGARGE--RGFPGERGVQGPPGPAGPRGANGAPGN 705



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 76/288 (26%), Positives = 91/288 (31%), Gaps = 50/288 (17%)

Query: 16  SANEMKSGGGPGPSGSETPPPP------RRAVLSPGSVFSPG----RG--ASFLFPPAES 63
           S  +  + G PGP G + PP P      R A   PG    PG    RG   S  FP A+ 
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500

Query: 64  LSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPG 123
           ++   P+ P G R            G          P   G L G        G   PPG
Sbjct: 501 VA--GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG-LTGSPGSPGPDGKTGPPG 557

Query: 124 PEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSS 183
           P     +                 G   A  QA       P+    G A  P     R  
Sbjct: 558 PAGQDGR-------------PGPPGPPGARGQAGVMGFPGPK----GAAGEPGKAGERGV 600

Query: 184 SQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAP 243
             PPG V   G   E       G Q P      +G +G      S    G   LPG A P
Sbjct: 601 PGPPGAVGPAGKDGEA------GAQGPPGPAGPAGERGEQGPAGS---PGFQGLPGPAGP 651

Query: 244 TGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAP 291
            G EA  P      E+G+P       P+     +RG   PG R    P
Sbjct: 652 PG-EAGKPG-----EQGVPGDLGAPGPSGAR-GERG--FPGERGVQGP 690



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 66/284 (23%), Positives = 90/284 (31%), Gaps = 27/284 (9%)

Query: 17   ANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWR 76
            A E  S G  GP+G+   P P+      G V  PG+     FP     S E  +      
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990

Query: 77   SGRRRLNSSSG----------SGSGSSGSSVSSPSWAGR--LRGDRQQVVAAGTLSPPGP 124
            SG R      G          SG   +  +  SP   G    +GDR +   AG    PG 
Sbjct: 991  SGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050

Query: 125  EEAKRKLRILQRELQNVQVNQ-----KVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCP 179
              A   +    +     +         VG   A   A       P+ PR  +  +     
Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPA------GPQGPRGDKGETGE--- 1101

Query: 180  FRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPG 239
             +      G     G +       S GEQ P  +   +G +G P    +  K G+  LPG
Sbjct: 1102 -QGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPG 1160

Query: 240  RAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTP 283
               P G   +   A      G P  P    P +   D    P P
Sbjct: 1161 PIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQP 1204



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 124/503 (24%), Positives = 154/503 (30%), Gaps = 87/503 (17%)

Query: 22  SGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPE----EPRSPGGWRS 77
           + G PGP+G   PP    AV + G     G        P  S  P+    EP  PG   +
Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAGPQG--------PRGSEGPQGVRGEPGPPGPAGA 381

Query: 78  GRRRLNSSSGSGSGSSGSSVSSPSWAGR--LRGDRQQVVAAGTLSPPGPEEAKRKLRILQ 135
                N  +    G+ G++  +P  AG     G R      G   PPGP+          
Sbjct: 382 AGPAGNPGADGQPGAKGAN-GAPGIAGAPGFPGARGPSGPQGPGGPPGPK---------- 430

Query: 136 RELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPR-LGRARSPSPCPFRSSSQPPGRVLVQG 194
                                 S    AP S    G    P P   +    P G    +G
Sbjct: 431 --------------------GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRG 470

Query: 195 ARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGS--EAQGP- 251
           AR E   T   G           G  G   +   +   G    PG A P GS  EA  P 
Sbjct: 471 ARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG 530

Query: 252 SAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVT 311
            A +   KG+  SP    P      K G P P  +       G  G     A   A  + 
Sbjct: 531 EAGLPGAKGLTGSPGSPGPDG----KTGPPGPAGQDGRPGPPGPPG-----ARGQAGVMG 581

Query: 312 STGPHRPQDLALTEPSGRARELEDLQPPEAL------VERQGQFLGSETSPAPERGGPRD 365
             GP      A  EP G+A E     PP A+       E   Q       PA ERG    
Sbjct: 582 FPGPKG----AAGEP-GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636

Query: 366 GEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSR-LPRALASVGPE 424
              PG  G    P G PG    E GK  E+       A         R  P      GP 
Sbjct: 637 AGSPGFQGLPG-PAGPPG----EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP 691

Query: 425 EARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQ--PGTGNVEAGIP---------SG 473
                    G       + + G+P      G+P  Q  PG     AG+P           
Sbjct: 692 GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA-AGLPGPKGDRGDAGP 750

Query: 474 RMLEPLPCWDAAKDLKEPQCPPG 496
           +  +  P  D  + L  P  PPG
Sbjct: 751 KGADGSPGKDGVRGLTGPIGPPG 773


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 100/356 (28%), Positives = 127/356 (35%), Gaps = 73/356 (20%)

Query: 191  LVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQG 250
            L Q + + + R +     CP+    + G  G   L       G P LPGR    G +   
Sbjct: 1233 LCQASFTTQPRPEPCPVYCPKGQKGEPGEMG---LRGQVGPPGDPGLPGRTGAPGPQGPP 1289

Query: 251  PSAFVRMEKGIP-ASPRCGSPTAMEIDKRGSP-TPGTRSCLAPSLGLFGASLTMATEVAA 308
             SA  + E+G P A  R GSP      + G+P TPG    L  S GL G           
Sbjct: 1290 GSATAKGERGFPGADGRPGSP-----GRAGNPGTPGAPG-LKGSPGLPGP--------RG 1335

Query: 309  RVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER-GGPRDGE 367
                 GP  P+     EP                    GQ +G E    P R G P    
Sbjct: 1336 DPGERGPRGPKG----EPGA-----------------PGQVIGGEGPGLPGRKGDPGPSG 1374

Query: 368  PPGKMG-------KGYLPCGMPGSG-EPEVGKRPEETTVSVQSAESSDSLSWSRLPRALA 419
            PPG  G       +G  P G+PG+  + + G R E         E   +     LP    
Sbjct: 1375 PPGPRGPLGDPGPRG--PPGLPGTAMKGDKGDRGERGPPG--PGEGGIAPGEPGLPGLPG 1430

Query: 420  SVGPEEARSGAPVG--GGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLE 477
            S GP+      PVG  G + +  D  E G+P L    GSP  Q   G   A  P G    
Sbjct: 1431 SPGPQ-----GPVGPPGKKGEKGDS-EDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGF 1484

Query: 478  PLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRG----TGVQSE 529
            P P  +A +  K  + PPG      P  SR   G   + G     G    TG Q E
Sbjct: 1485 PGPLGEAGE--KGERGPPG------PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGE 1532



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 103/412 (25%), Positives = 138/412 (33%), Gaps = 66/412 (16%)

Query: 187  PGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLC---SSQVKKGMPPLPGRAAP 243
            PG+   +G R         GE+  +    + GR G P        + + G P  PGR   
Sbjct: 1651 PGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD 1710

Query: 244  TGSEA-----------QGPSAFVRMEKGIPASPRCGSPTAMEIDK-RGSP----TPGTRS 287
            TG  A           +GP    R  KG P  P  G+P    I+  RG P     PG R 
Sbjct: 1711 TGPGAREKGEPGDRGQEGP----RGPKGDPGLP--GAPGERGIEGFRGPPGPQGDPGVRG 1764

Query: 288  CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347
                        L   + +  +  + GP        + P+G A +  D         R  
Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGP--------SGPNGAAGKAGDPGRDGLPGLRGE 1816

Query: 348  QFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSD 407
            Q L   + P    G P +   PG  GK   P G PG    E G++ E+        E  D
Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP-GDPG----EDGRKGEKGDSGASGREGRD 1871

Query: 408  SLSWSR-LPRALASVGPE----------EARSGAPVG----GGRWQLSDRVEGGSPTLGL 452
                 R  P  L   GP           +   G P G    G R +   + E G P    
Sbjct: 1872 GPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERG 1931

Query: 453  LGGSPSAQPGTGNV--EAGIPSGRMLEPLPCWDAAKDLKEP-----QCPPGDRVGVQPGN 505
            L G P + P    +   AGI +  + E +  WD +     P     + P GD     P  
Sbjct: 1932 LRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPG 1991

Query: 506  SRVWQGTMEKAGLAWTRG-TGVQS-EGTWESQRQDSDALPSPELLPQDPDKP 555
                 G   + GL   RG  G Q   G    +R      P P  L  +P KP
Sbjct: 1992 KEGPIGFPGERGLKGDRGDPGPQGPPGLALGER----GPPGPSGLAGEPGKP 2039



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 115/479 (24%), Positives = 155/479 (32%), Gaps = 126/479 (26%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
            G PGPSG   PP PR  +  PG    PG                    PG    G +   
Sbjct: 1368 GDPGPSG---PPGPRGPLGDPGPRGPPGL-------------------PGTAMKGDKGDR 1405

Query: 84   SSSGS-GSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQ 142
               G  G G  G +   P   G       Q    G + PPG +  K              
Sbjct: 1406 GERGPPGPGEGGIAPGEPGLPGLPGSPGPQ----GPVGPPGKKGEKG------------- 1448

Query: 143  VNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRT 202
                            S   AP  P  G+  SP     +    PPG +  +G R      
Sbjct: 1449 ---------------DSEDGAPGLP--GQPGSPGE---QGPRGPPGAIGPKGDR------ 1482

Query: 203  KSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIP 262
               G   P     + G +G P    S   +G+P + GR    G E        + EKG P
Sbjct: 1483 ---GFPGPLGEAGEKGERGPPGPAGS---RGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536

Query: 263  ASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLA 322
              P  G P  +     G    G +  + P+ G  GA+              G   P  L 
Sbjct: 1537 GRP--GDPAVVGPAVAG--PKGEKGDVGPA-GPRGATGVQ-----------GERGPPGLV 1580

Query: 323  LTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMP 382
            L    G   +  D + P  L  R G     ++ P  E+G P    PPG +G        P
Sbjct: 1581 LPGDPGPKGDPGD-RGPIGLTGRAGP--PGDSGPPGEKGDPGRPGPPGPVG--------P 1629

Query: 383  GSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDR 442
               + EVG++ +E                      L     E    GAP  G R  + ++
Sbjct: 1630 RGRDGEVGEKGDEGPPG---------------DPGLPGKAGERGLRGAP--GVRGPVGEK 1672

Query: 443  VEGGSPTLGLLGGSP-SAQPGTGNVEAGIPS--GRMLEPLPCWDAAKDLKEPQCPPGDR 498
             + G P      GSP S+ P     E G P   GR+++  P    A++  E    PGDR
Sbjct: 1673 GDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGP---GAREKGE----PGDR 1724



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 124/523 (23%), Positives = 166/523 (31%), Gaps = 92/523 (17%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
            G  G  G + PP        PG+   PG       PP   +S +EP        G   L 
Sbjct: 2067 GERGEQGRDGPPG------LPGTPGPPG-------PPGPKVSVDEPGPGLSGEQGPPGLK 2113

Query: 84   SSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQV 143
             + G    +             ++GDR +    G    PG          L  E      
Sbjct: 2114 GAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPG----------LPGERGMAGP 2163

Query: 144  NQKVGMFEAHIQAQSSAIQAPRSP--RLGRARSPSPCPFRSSSQPPGRVLVQGARSEERR 201
              K G            +Q PR P   +G    P P      + P G     G + E   
Sbjct: 2164 EGKPG------------LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGE 2211

Query: 202  TKSWGEQCPETSGTDS-----------GRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQG 250
            T   G      +G              G +G P L     + G P  PGR   +G +   
Sbjct: 2212 TGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGD- 2270

Query: 251  PSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAP-SLGLFGASLTMATEVAAR 309
                 R   G+P SP    P   + +   +  PG      P + G  GA   +A ++   
Sbjct: 2271 -----RGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 310  VTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPE--RGGPRDGE 367
              + G     D  L  P G   E      P    E      G + +P P+  +G P  G 
Sbjct: 2326 PGAKG-----DRGLPGPRGEKGEAGRAGEPGDPGED-----GQKGAPGPKGFKGDPGVGV 2375

Query: 368  P--PGKMG----KGYLPCGMPG-SGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS 420
            P  PG  G    KG L  G+PG  G P V   P +T    +  +   S       R LA 
Sbjct: 2376 PGSPGPPGPPGVKGDL--GLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE-----RGLAG 2428

Query: 421  VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP 480
                E   G P+G      S    G S   G  G      PG    E G P  R  +  P
Sbjct: 2429 PPGREGIPG-PLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG-ERGEPGIRGEDGRP 2486

Query: 481  CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRG 523
              +  + L     PPG R        R  +G +  AGL   +G
Sbjct: 2487 GQEGPRGLTG---PPGSR------GERGEKGDVGSAGLKGDKG 2520



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 96/397 (24%), Positives = 136/397 (34%), Gaps = 70/397 (17%)

Query: 24   GGPGPSGSE--TPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRR- 80
            G PGPSG      PP R  +  PG +  PG   S + PP  S    +   PG    G R 
Sbjct: 2416 GQPGPSGERGLAGPPGREGI--PGPLGPPGPPGS-VGPPGASGLKGDKGDPGVGLPGPRG 2472

Query: 81   -----RLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAG----------TLSPPGPE 125
                  +    G         ++ P  +   RG++  V +AG           L PPGP 
Sbjct: 2473 ERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR 2532

Query: 126  EAK-----RKLRILQREL----QNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPS 176
             AK     R  R L  +      N     K    E   +  S+ +   R   LG    P 
Sbjct: 2533 GAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKG-SAGLPGLRG-LLGPQGQPG 2590

Query: 177  PCPFRSSSQPPGRVLVQGARSE--------------ERRTK-SWGEQCPETSGTDSGRKG 221
                      PG+  V G R E              ER  K + G    +    ++G  G
Sbjct: 2591 AAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPG 2650

Query: 222  GPSLCSSQVKKGMPPLPGRAAPTGSEAQ-GPSAFVRMEKGIPASPRCGSPTAMEIDKRGS 280
             P L   + + G P +PG++   G E   GP      ++G    P    P   + +K   
Sbjct: 2651 RPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKG----DRGFDGQP---GPKGDQGEKGER 2703

Query: 281  PTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPE 340
             TPG      PS G  G++            S GP  P+ L       + ++ E   P E
Sbjct: 2704 GTPGIGGFPGPS-GNDGSA-----GPPGPPGSVGPRGPEGL-------QGQKGERGPPGE 2750

Query: 341  ALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYL 377
             +V   G  +        E+G P    P G+ G+  L
Sbjct: 2751 RVVGAPG--VPGAPGERGEQGRPGPAGPRGEKGEAAL 2785



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 122/519 (23%), Positives = 162/519 (31%), Gaps = 108/519 (20%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
            G PG  G + PP        PG V  PG+G               P  PGG  +G +   
Sbjct: 1878 GAPGILGPQGPPG------LPGPVGPPGQGF--------------PGVPGG--TGPKGDR 1915

Query: 84   SSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQV 143
              +GS  G  G           L G+R      G    PG      +L     E   ++ 
Sbjct: 1916 GETGS-KGEQG-----------LPGER------GLRGEPGSVPNVDRLL----ETAGIKA 1953

Query: 144  NQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTK 203
            +    + E   ++  S +  P   R  +  S           PPG+    G   E     
Sbjct: 1954 SALREIVETWDESSGSFLPVPERRRGPKGDS-------GEQGPPGKEGPIGFPGERGLKG 2006

Query: 204  SWGEQCPE-TSGTDSGRKG--GPS-LCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEK 259
              G+  P+   G   G +G  GPS L     K G+P LPGRA   G   +      R EK
Sbjct: 2007 DRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEK 2066

Query: 260  ------------GIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMAT--- 304
                        G+P +P    P   ++     P PG      P  GL GA     +   
Sbjct: 2067 GERGEQGRDGPPGLPGTPGPPGPPGPKVSV-DEPGPGLSGEQGPP-GLKGAKGEPGSNGD 2124

Query: 305  -----------------EVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347
                             E   R     P  P +  +  P G+        PP        
Sbjct: 2125 QGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGP------ 2178

Query: 348  QFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPG-SGEPEVGKRPEETTVSVQSAESS 406
              +G    P P  G P    P G  G   L  G PG +G P  G       V +      
Sbjct: 2179 --VGGHGDPGPP-GAPGLAGPAGPQGPSGLK-GEPGETGPPGRGLTGPTGAVGLPGPPGP 2234

Query: 407  DSLSWSRLPRALASVGPEEARSGAP-VGGGRWQLSDRVEGGSP-TLGLLG-----GSPSA 459
              L   +    L     E  + GAP   G   +  DR   G P + GL G     G P  
Sbjct: 2235 SGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGP 2294

Query: 460  QPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDR 498
                G    G+P  +  +  P   A   + EP    GDR
Sbjct: 2295 TGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGA-KGDR 2332


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 114/486 (23%), Positives = 155/486 (31%), Gaps = 59/486 (12%)

Query: 20  MKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGG----- 74
           M + G PGP+G+   P  R     PG   + G       P  E      P  PG      
Sbjct: 410 MGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG----PRGERGEAGIPGVPGAKGEDG 465

Query: 75  --WRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRK-- 130
                G    N   G+           P+    + G++      G   P GP  A  +  
Sbjct: 466 KDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525

Query: 131 ---------LRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFR 181
                    +R +         + K G   +  ++       P  PR        P P  
Sbjct: 526 RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG 585

Query: 182 SSSQP--------PGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKG 233
           +   P        PG    QG   +   T   G   P   G D G  G P        +G
Sbjct: 586 NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPG------PQG 639

Query: 234 MPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSL 293
           +  LPG   P G   +      + + G P +P  G   A    +RG P       LA + 
Sbjct: 640 LQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG-GKGDAGAPGERGPPG------LAGAP 692

Query: 294 GLFGASLTMATEVAARVTSTGPHRPQDLALTEP-SGRARELEDLQPPEALVERQGQFLGS 352
           GL G +     E      + GP  P   A T    G   E   L  P    ++ G+  G 
Sbjct: 693 GLRGGAGPPGPE--GGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK-GEPGGP 749

Query: 353 ETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWS 412
                P + GPR   P G +G    P G PG    + G+        +     S      
Sbjct: 750 GADGVPGKDGPRG--PTGPIGPPG-PAGQPG----DKGEGGAPGLPGIAGPRGSPGERGE 802

Query: 413 RLPRALASVGPEEARSGAPVG-GGRWQLSDRVEGGSP-TLGLLGGS-PSAQPGTGNV--E 467
             P   A       ++G P G G R    ++ EGG P   G  GGS P+  PG   V  E
Sbjct: 803 TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGE 862

Query: 468 AGIPSG 473
            G P G
Sbjct: 863 RGSPGG 868



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 102/553 (18%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPG----RGASFL-FPPAESLSPEEPRSPGGWRSG 78
           G PGP G    P  R     PG+  + G    RG+     PP    +   P SPG     
Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGA---- 349

Query: 79  RRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQREL 138
           +  +  +   GS  +      P   G           AG   PPGP              
Sbjct: 350 KGEVGPAGSPGSNGAPGQRGEPGPQGH----------AGAQGPPGPPGI----------- 388

Query: 139 QNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSE 198
            N     K  M  A I         P +P L  AR P P P  ++  P     ++G   E
Sbjct: 389 -NGSPGGKGEMGPAGI---------PGAPGLMGARGP-PGPAGANGAPG----LRGGAGE 433

Query: 199 ERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPG----------RAAPTGSEA 248
             +  + GE  P     ++G  G P       K G P  PG          R AP     
Sbjct: 434 PGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGP 493

Query: 249 QGPSAFVRMEKGIPASPRCGSP-------TAMEIDKRGSP-TPGTRSCLAPSLGLFGA-- 298
            GP+  +  EKG PA  R G+P        A E  + G P  PG R  +  S G  G+  
Sbjct: 494 AGPNG-IPGEKG-PAGER-GAPGPAGPRGAAGEPGRDGVPGGPGMRG-MPGSPGGPGSDG 549

Query: 299 --SLTMATEVAARVTSTGPHRPQD----LALTEPSGR----ARELEDLQP----PEALVE 344
                 +   + R    GP  P+     +    P G      +  E   P    P+    
Sbjct: 550 KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPG 609

Query: 345 RQGQFLGSETSPAPERGGPRDGE--PPGKMGKGYLP--CGMPG-SGEP-EVGKRPEETTV 398
           + G+  G +  P P   G   G+  PPG  G   LP   G PG +G+P E G + +    
Sbjct: 610 KNGE-TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP 668

Query: 399 SVQSAESSDSLSWSRLPRALASVGPEEARSGA-PVG--GGRWQLSDRVEGGSPTLGLLGG 455
                +        R P  LA  G    R GA P G  GG+         G+     L G
Sbjct: 669 GAPGGKGDAGAPGERGPPGLA--GAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726

Query: 456 SPSAQPGTGNV----EAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQG 511
            P  + G G+     + G P G   + +P  D  +    P  PPG     QPG+ +   G
Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP--AGQPGD-KGEGG 783

Query: 512 TMEKAGLAWTRGT 524
                G+A  RG+
Sbjct: 784 APGLPGIAGPRGS 796



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 71/256 (27%), Positives = 86/256 (33%), Gaps = 61/256 (23%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESL-----SPEEPRSPGGWRSG 78
            G PG SG   PP P+      GS   PG      FP A  L     S   P  PG   S 
Sbjct: 843  GPPGGSGPAGPPGPQGVKGERGSPGGPGAAG---FPGARGLPGPPGSNGNPGPPGPSGSP 899

Query: 79   RRRLNSSSGSGSGSSGS-SVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRE 137
             +         +G+ GS  VS P      +GD  Q    G+    GP  A   L I    
Sbjct: 900  GKDGPPGPAGNTGAPGSPGVSGP------KGDAGQPGEKGSPGAQGPPGAPGPLGI---- 949

Query: 138  LQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARS 197
                      G+  A   A    +  PR        SP P   +  S  PG   + G R 
Sbjct: 950  ---------AGITGARGLAGPPGMPGPRG-------SPGPQGVKGESGKPGANGLSGERG 993

Query: 198  EERRTKSWGEQ-CPETSGT--DSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAF 254
                    G Q  P  +GT  + GR G P         G   LPGR    G +       
Sbjct: 994  PP------GPQGLPGLAGTAGEPGRDGNP---------GSDGLPGRDGSPGGKGD----- 1033

Query: 255  VRMEKGIPASPRCGSP 270
             R E G P +P  G+P
Sbjct: 1034 -RGENGSPGAP--GAP 1046



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 31/101 (30%), Positives = 36/101 (35%), Gaps = 6/101 (5%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
            G  G SG   PP P+      G+   PGR  +    P     P    SPGG   G R  N
Sbjct: 984  GANGLSGERGPPGPQGLPGLAGTAGEPGRDGN----PGSDGLPGRDGSPGG--KGDRGEN 1037

Query: 84   SSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGP 124
             S G+           P       GDR +   AG    PGP
Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGP 1078



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 134/550 (24%), Positives = 165/550 (30%), Gaps = 121/550 (22%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAE--SLSPEEPRSPGGWRSGRRR 81
           G PGP+G   PP P      PGS  SPG    +  PP E     P  P  P G       
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPG----YQGPPGEPGQAGPSGPPGPPG------- 219

Query: 82  LNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNV 141
             +   SG          P   G  RG        G    PG    K       R  +  
Sbjct: 220 --AIGPSGPAGKDGESGRPGRPGE-RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276

Query: 142 QVNQKVGMFEAHIQAQSSAIQAPRSPR-----LGRARSPSPCPFRSSS------------ 184
           +        E  +  ++ A   P  PR      GR   P     R +             
Sbjct: 277 ETGAPGLKGENGLPGENGA-PGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP 335

Query: 185 QPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPG-RAAP 243
            PPG     G+   +      G   P ++G   G++G P        +G P  PG   +P
Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAGS--PGSNGA-PGQRGEPGPQGHAGAQGPPGPPGINGSP 392

Query: 244 TGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMA 303
            G    GP+       GIP +P         +  RG P P   +  AP  GL G +    
Sbjct: 393 GGKGEMGPA-------GIPGAPGL-------MGARGPPGPAGANG-AP--GLRGGAGEPG 435

Query: 304 TEVAARVTSTGPHRPQDLALTEPSGRARELEDLQP--------PEALVERQGQ-FLG--- 351
              A         R +      P  +  + +D  P        P A  ER    F G   
Sbjct: 436 KNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG 495

Query: 352 -----SETSPAPERGGPRDGEPPGKMGK--------GYLPCGMPGS--GEPEVGKRPEET 396
                 E  PA ERG P    P G  G+        G    GMPGS  G    GK     
Sbjct: 496 PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555

Query: 397 TVSVQSAESSDSLSWSR-LPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGG 455
           +            S  R  P  +   GP +   GAP   G        E G P     G 
Sbjct: 556 SQGESGRPGPPGPSGPRGQPGVMGFPGP-KGNDGAPGKNG--------ERGGPG----GP 602

Query: 456 SPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEK 515
            P   PG  N E G                     PQ PPG      PG  +   G    
Sbjct: 603 GPQGPPGK-NGETG---------------------PQGPPGP---TGPGGDKGDTGPPGP 637

Query: 516 AGLAWTRGTG 525
            GL    GTG
Sbjct: 638 QGLQGLPGTG 647


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 137/571 (23%), Positives = 185/571 (32%), Gaps = 100/571 (17%)

Query: 26  PGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEP---RSP--GGWRSGRR 80
           P P    TPP P     S      P   A    PP   +SP  P   RSP  G  + G+ 
Sbjct: 111 PTPKPIVTPPGPAAGESSAMEGMFPVHWAGRGSPPPALISPASPATQRSPGEGAQQPGKC 170

Query: 81  RLNSSSG-SGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS------PP-------GPEE 126
            +  SSG S  G++ S+  + + AG+      Q V +G  S      PP        PEE
Sbjct: 171 LVCPSSGNSERGTNTSAELALALAGKREMQGCQRVCSGDRSVRRRAHPPVHAPARSHPEE 230

Query: 127 AKR---------KLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSP 177
           A+           LR+  R +   +  +       H  A       P     G  R+  P
Sbjct: 231 ARALALPAPTRVHLRLAARCVGRRRRERSDPPGSYHDPALGLRTPGPILEGRG-PRAAGP 289

Query: 178 CPFRSSS---QPPGRVLVQGARSEERRTKSWGEQCPETSGTD----SGRKGGPSLCSSQV 230
           CP  +++      G   V G    +RR      +     G+     S R   PS+C    
Sbjct: 290 CPANTAAVDKTQGGWRAVSGRAEAQRRAADHHSRLRTALGSGLRVCSSRPAAPSVCP--- 346

Query: 231 KKGMPPLPGRA-APTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCL 289
            +G PP PG   +  G+ A       R     PA  R     A    +RG      R+  
Sbjct: 347 VRGPPPRPGTVRSQLGARANEGGGAPRP----PAGARVFGVWARGRLRRGCHKCADRAPR 402

Query: 290 APSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARE-----LEDLQPPEALVE 344
           AP      A              T P  P+      P+   R      L+ L P +    
Sbjct: 403 APKAAAKAAPAKRTARRRXXXXDTVPAAPEGAGAARPAAPLRPTSFSVLDILDPNKFNSR 462

Query: 345 RQGQFLGSETSP---APERGGP------RDGEPP-----------GKMGKGYLPCGMPGS 384
           R+   L    +P   AP    P        G PP           G  G G      P +
Sbjct: 463 RRRCVLLGPVAPAACAPCASAPCAPAPAASGRPPRAEELERRALAGAGGVGAAGAEPPNA 522

Query: 385 GEP-EVGKRPEETTVSVQ--------SAESSDSL------SWSRLPRALASVGPEEARSG 429
           G+P + G+     T            SA+S D +           P   A+ G EEAR G
Sbjct: 523 GDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGG 582

Query: 430 APVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPL---PCWDAAK 486
              GGG        +G + T         A PG    EA  P  R   P+   P   AA 
Sbjct: 583 ---GGGLGARGSGCQGAAET--------DASPGATVDEAAAPGPRENSPVAPGPPGGAAA 631

Query: 487 DLKEPQCPPGDRVGVQPGNSRVWQGTMEKAG 517
                  P G     +P   R   G+  K+G
Sbjct: 632 PGGAGTTPQGTATAAKPKRKRT--GSDSKSG 660


>gi|239749196 PREDICTED: hypothetical protein XP_002346951 [Homo
           sapiens]
          Length = 528

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 59/195 (30%), Positives = 73/195 (37%), Gaps = 30/195 (15%)

Query: 174 SPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSG----RKGGPSLCSSQ 229
           SP+ CP RS       +L   ARS  RR +  G   PE S   SG      G P     +
Sbjct: 189 SPASCPSRSCPSAAVFILAVAARSCSRRRRV-GTSGPEASTLSSGLLTCSAGEPPTTGGK 247

Query: 230 VKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGI--PASPRCGSPTAMEIDKRGSPTPGTRS 287
           +  G   L    AP  +    P   +R   G   P SP  G       D RG+PTPG   
Sbjct: 248 L-TGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGP------DARGAPTPGR-- 298

Query: 288 CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347
                    G +   AT     +   GP RPQ L +   S R R +     P A+V R  
Sbjct: 299 ------ARGGGASWSATPTT--IPGPGPPRPQLLVIPRTS-RCRLV-----PAAVVGRSS 344

Query: 348 QFLGSETSPAPERGG 362
                 + PA  RGG
Sbjct: 345 SVTIDHSRPASSRGG 359


>gi|239743276 PREDICTED: hypothetical protein XP_002342815 [Homo
           sapiens]
          Length = 528

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 59/195 (30%), Positives = 73/195 (37%), Gaps = 30/195 (15%)

Query: 174 SPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSG----RKGGPSLCSSQ 229
           SP+ CP RS       +L   ARS  RR +  G   PE S   SG      G P     +
Sbjct: 189 SPASCPSRSCPSAAVFILAVAARSCSRRRRV-GTSGPEASTLSSGLLTCSAGEPPTTGGK 247

Query: 230 VKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGI--PASPRCGSPTAMEIDKRGSPTPGTRS 287
           +  G   L    AP  +    P   +R   G   P SP  G       D RG+PTPG   
Sbjct: 248 L-TGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGP------DARGAPTPGR-- 298

Query: 288 CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347
                    G +   AT     +   GP RPQ L +   S R R +     P A+V R  
Sbjct: 299 ------ARGGGASWSATPTT--IPGPGPPRPQLLVIPRTS-RCRLV-----PAAVVGRSS 344

Query: 348 QFLGSETSPAPERGG 362
                 + PA  RGG
Sbjct: 345 SVTIDHSRPASSRGG 359


>gi|239508959 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 528

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 59/195 (30%), Positives = 73/195 (37%), Gaps = 30/195 (15%)

Query: 174 SPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSG----RKGGPSLCSSQ 229
           SP+ CP RS       +L   ARS  RR +  G   PE S   SG      G P     +
Sbjct: 189 SPASCPSRSCPSAAVFILAVAARSCSRRRRV-GTSGPEASTLSSGLLTCSAGEPPTTGGK 247

Query: 230 VKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGI--PASPRCGSPTAMEIDKRGSPTPGTRS 287
           +  G   L    AP  +    P   +R   G   P SP  G       D RG+PTPG   
Sbjct: 248 L-TGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGP------DARGAPTPGR-- 298

Query: 288 CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347
                    G +   AT     +   GP RPQ L +   S R R +     P A+V R  
Sbjct: 299 ------ARGGGASWSATPTT--IPGPGPPRPQLLVIPRTS-RCRLV-----PAAVVGRSS 344

Query: 348 QFLGSETSPAPERGG 362
                 + PA  RGG
Sbjct: 345 SVTIDHSRPASSRGG 359


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 78/355 (21%), Positives = 121/355 (34%), Gaps = 64/355 (18%)

Query: 59   PPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGT 118
            PP E L P +   PG   S +   +   G  SG                          T
Sbjct: 3623 PPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRH------------------------T 3658

Query: 119  LSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPC 178
               PG   AK   R L             G  EA   +Q S+  AP  P+ G+   PS  
Sbjct: 3659 GEEPGRRAAKPHARDL-------------GRHEARPHSQPSS--APAMPKKGQPGYPSSA 3703

Query: 179  PFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLP 238
             +   SQP             R + ++        G+     G  +L S    +  P L 
Sbjct: 3704 EY---SQP------------SRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQ 3748

Query: 239  GR-AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFG 297
            GR AAP   ++Q PS+     + IP+      P   +  +     P  ++     L    
Sbjct: 3749 GRQAAPGPQQSQSPSS-----RQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQS 3803

Query: 298  ASLTMATEVAARVTSTGPH-RPQDLALTEPSGRAR-ELEDLQPPEALVERQGQFLGSETS 355
               T  +  AA   +  P   P      +P+G  R E  +     A   +QG+   ++ +
Sbjct: 3804 QPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPA 3863

Query: 356  PAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLS 410
            P P   G + G  PG  G    P G PG+    V  +      + Q+ + ++++S
Sbjct: 3864 PGPGPAGVKAGARPG--GTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVS 3916



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 58/260 (22%), Positives = 89/260 (34%), Gaps = 29/260 (11%)

Query: 20   MKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAE-----SLSPEEP----R 70
            MK  GGP   G  T P    A +S  +  S       + P        +   ++P     
Sbjct: 1301 MKQNGGPLTPG--TSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358

Query: 71   SPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRK 130
            SP    S  + +      G G+  ++  +P  AG  RG       AG+   P P      
Sbjct: 1359 SPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHS 1418

Query: 131  LRILQRELQNVQVNQKVGMFEAHIQAQS-SAIQAPRSPRLGRARSPSPC---PFRSSSQP 186
                          + +    + + A   +A + P S   G   +P P     + +SS P
Sbjct: 1419 YGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSP 1478

Query: 187  PGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGS 246
            P    +  +   E  T S G+  P  +   S +   P+  S      MP  PG   P+  
Sbjct: 1479 P----LSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASD-----MPRSPGAPTPSPM 1529

Query: 247  EAQGPSAFVRMEKGIPASPR 266
             AQG     R     P++PR
Sbjct: 1530 VAQGTQTPHR-----PSTPR 1544



 Score = 33.5 bits (75), Expect = 0.96
 Identities = 52/223 (23%), Positives = 78/223 (34%), Gaps = 22/223 (9%)

Query: 163 APRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGG 222
           APRS    +  SP+  P  S ++ P      G   +ER     G Q     G+       
Sbjct: 233 APRSKSQQQLHSPALSPAHSPAKQP-----LGKPDQERSRGPGGPQ----PGSRQAETAR 283

Query: 223 PSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPT 282
            +      +   PP  GR +P   +   PS      +  P +    + +A  +      T
Sbjct: 284 ATSVPGPAQAAAPPEVGRVSPQPPQPTKPST----AEPRPPAGEAPAKSATAVPAGLGAT 339

Query: 283 PGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEAL 342
             T+  L   L   GASL      A+ + S  P            G  + + +    +A 
Sbjct: 340 EQTQEGLTGKLFGLGASLLTQ---ASTLMSVQPEADTQGQPAPSKGTPKIVFN----DAS 392

Query: 343 VERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSG 385
            E   + LGS   P P  G     EP  +MG G  P  +P +G
Sbjct: 393 KEAGPKPLGSGPGPGPAPGAKT--EPGARMGPGSGPGALPKTG 433


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 73/272 (26%), Positives = 94/272 (34%), Gaps = 70/272 (25%)

Query: 161 IQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRK 220
           +Q P  P+  +    + CP        G V     R  +   K  GEQ PE  G   G+ 
Sbjct: 710 VQGPAGPKGEKGDGCTACPSLQ-----GTVTDMAGRPGQPGPK--GEQGPEGVGRP-GKP 761

Query: 221 GGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRC-GSPTAMEIDKRG 279
           G P L   Q   G+  + G   P G   QGP      E G P  P   G P       RG
Sbjct: 762 GQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQG----EPGAPGLPGIQGLP-----GPRG 812

Query: 280 SPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRAREL------ 333
            P P        S G+ GA              TGP  P   +++ P GR  +       
Sbjct: 813 PPGPTGEKGAQGSPGVKGA--------------TGPVGPPGASVSGPPGRDGQQGQTGLR 858

Query: 334 ----------EDLQPPEALVERQGQ------------FLGSETSPAPERGGPRDGEPPGK 371
                     E  +P E     QG             ++GS   P P+ G P    PPG 
Sbjct: 859 GTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQ-GPPGIPGPPGP 917

Query: 372 MGKGYLPCGMPGS----GEP----EVGKRPEE 395
            G   L  G+PG+    G+P    E+G  P E
Sbjct: 918 PGVPGLQ-GVPGNNGLPGQPGLTAELGSLPIE 948



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 26/105 (24%), Positives = 37/105 (35%), Gaps = 9/105 (8%)

Query: 170  GRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQ 229
            G    P P        PPG    +G R  +  +   G+Q         G +G P      
Sbjct: 1114 GEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQ---------GFQGQPGFPGPP 1164

Query: 230  VKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAME 274
               G P   G   P G +A+  S  +R   G+P SP    P  ++
Sbjct: 1165 GPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQ 1209



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 124/541 (22%), Positives = 166/541 (30%), Gaps = 100/541 (18%)

Query: 24   GGPGPSGSETPPPPRRAVLSPGSVFSPG-------RGASFLF-------PPAESLSPEEP 69
            G PG  GS  PP P      PG+V SPG       RG + L        PP +   P   
Sbjct: 1036 GPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT 1095

Query: 70   RSPG--GWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRL--------------RGDRQQV 113
              PG  G +  R    S+   G      S   P   G                +GD+   
Sbjct: 1096 GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQ 1155

Query: 114  VAAGTLSPPGPEEAKRKLRI-----LQRELQNVQVNQKVGMFEAHIQAQSSAIQAP---- 164
               G   PPGP     K+        Q E  +  +    G+  +        IQ P    
Sbjct: 1156 GQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLD 1215

Query: 165  ----RSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRK 220
                +  + G    P P        PPG     G           G+  P  S    G +
Sbjct: 1216 GLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAE 1275

Query: 221  GGPSLCSSQVKKGMPPLPGRAAPTGSEAQ-GPSAFVRM----------EKGIPASPRCGS 269
            G P     Q   G P  PG   P G   Q GP+    +          E+G+   P    
Sbjct: 1276 GEPGAMGPQ---GRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPG 1332

Query: 270  PTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQ-DLALTEPSG 328
            P        G P P        + G  G           +    GP  P+ D       G
Sbjct: 1333 PP-------GHPGPPGEPGTDGAAGKEGP--------PGKQGFYGPPGPKGDPGAAGQKG 1377

Query: 329  RARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGS---- 384
            +A E      P    +           PA ERG P     PG  G   LP G+PGS    
Sbjct: 1378 QAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHP---GAPGPSGSPGLP-GVPGSMGDM 1433

Query: 385  -GEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASV----GP--EEARSGAPVGGGRW 437
                E+ +   +  + +     +   S  + P  +A+     GP  ++   G P   G  
Sbjct: 1434 VNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP 1493

Query: 438  QLSDRVEGGSPTLGLLG--GSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPP 495
             L  ++ G     GL G  G P  +   G++  GI     L   P          PQ PP
Sbjct: 1494 GLPGQI-GREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPP---------GPQGPP 1543

Query: 496  G 496
            G
Sbjct: 1544 G 1544


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 108/443 (24%), Positives = 145/443 (32%), Gaps = 68/443 (15%)

Query: 28  PSGSETPPPPRRAVLSPGSV---------FSPGRGASFLFPPAESLSPEEPRSPGGWRSG 78
           PS   TPPP  R   +P             SPGR +  +    +    E+  SP      
Sbjct: 401 PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKV---TKHKGTEKRESPSPAPKP 457

Query: 79  RRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQREL 138
           R+   S S    G   ++  S     + R   QQ  +    S    +E  ++  +     
Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK---- 513

Query: 139 QNVQVNQKVGMFEAHIQAQSSAI-----QAPRSPRLGRARSPSPCPFR----SSSQPPGR 189
                N +VG    H  ++S++      Q   SPR  R RSPSP P R     S  PP R
Sbjct: 514 -----NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPR 568

Query: 190 VLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQ 249
                     RRT +   +    S     R   P   S  +++   P P     T S   
Sbjct: 569 ---------RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619

Query: 250 GPSAFVRMEKGIPASPRCG-SPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAA 308
            P    R     P   R   SP   +   R SP    RS    S    G+S + +T  A 
Sbjct: 620 PPKR--RASPSPPPKRRVSHSPPPKQ---RSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674

Query: 309 RVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPA--PERGGPRDG 366
                  H P       P  RA +     PP               SP+  P R   R  
Sbjct: 675 SPQPNKRHSP------SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP 728

Query: 367 EP--------PGKMGKGYLPCGMPGSGEPE-VGKRPEETTVSVQSAESSDSLSWS-RLPR 416
           EP        P       +      SG PE   K+P      VQS   S S +WS  +P 
Sbjct: 729 EPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQS--QSPSTNWSPAVPV 786

Query: 417 ALA---SVGPEEARSGAPVGGGR 436
             A   +  P   R+    GGG+
Sbjct: 787 KKAKSPTPSPSPPRNSDQEGGGK 809



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 66/299 (22%), Positives = 110/299 (36%), Gaps = 39/299 (13%)

Query: 122 PGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSP---- 177
           P PE+  +K +  ++     +   K     +  +++S +   PR     R+RS SP    
Sbjct: 259 PSPEKNSKKEKEKEKTRPRSRSRSKS---RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP 315

Query: 178 CPFRSSSQ----PPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKG 233
            P R  S     PP R+         RR++S   +   +S + SG     S   S+    
Sbjct: 316 SPRRRPSPRRRTPPRRM---PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPK 372

Query: 234 MPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTP-----GTRSC 288
            PP    + P  +    PSA     +  P+ P    P       R SPTP       +S 
Sbjct: 373 KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKT-----RHSPTPQQSNRTRKSR 427

Query: 289 LAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALT---EPSGRARELEDLQPPEALVER 345
           ++ S G     +T       R + +   +P+ + L+   E  G      D         R
Sbjct: 428 VSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRR 487

Query: 346 QGQFLGSETSPA-------PERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETT 397
           Q Q   S++  +       P+R   ++GE   +  + + P     S  P   KR +ET+
Sbjct: 488 QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR--RRHSP---SRSASPSPRKRQKETS 541


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 67/290 (23%), Positives = 99/290 (34%), Gaps = 37/290 (12%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
           G PG  G   PP  +     PG +  PG       PP     P  P  PG          
Sbjct: 694 GDPGNRGLPGPPGKKGQAGPPGVMGPPG-------PPG----PPGPPGPGCTMGLGFEDT 742

Query: 84  SSSGSGSGSSGSSVSSPSWAGRLRGDR--------QQVVAAGTLSPPGPEEAKRKLRILQ 135
             SGS    +   +S P+ A  L+G++        + +  A  + PPGP      +++L 
Sbjct: 743 EGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLS 802

Query: 136 RELQNV--------QVNQKVGMFEAHIQAQSSAIQAPRSPR--LGRARSPSPCPFRSSSQ 185
             L N+         + + VG               PR P+   G    P     +    
Sbjct: 803 NSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKG 862

Query: 186 PPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTG 245
            PG +L +    E    K  GE     +    G KG P     + + G+P  PGR    G
Sbjct: 863 EPGAILTEDIPLERLMGKK-GEPGMHGAPGPMGPKGPP---GHKGEFGLPGRPGRPGLNG 918

Query: 246 SEAQ--GPSAFVRMEKGIPASPRCGSPTAMEIDKRGS--PTPGTRSCLAP 291
            +     P   ++   G+P  P    P    I+ +G+  P P    C  P
Sbjct: 919 LKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMP 968


>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
          Length = 435

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 63/238 (26%), Positives = 91/238 (38%), Gaps = 24/238 (10%)

Query: 28  PSGSETPPPPRRAVLSPG----------SVFSP---GRGASFLFPPAESLSPEEPRSPGG 74
           P    TP PPRR + +P           SV +P    +  S      E+LSP  P   G 
Sbjct: 162 PPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREG- 220

Query: 75  WRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRIL 134
            R G  R  ++ G  SG  G   S P+     R     +V  G    P    ++  + + 
Sbjct: 221 -RPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQ 279

Query: 135 QRELQNV-QVNQKVGMFEAHIQAQSSAIQAPRSP-RLGRARS-PSPC-PFRSSSQPP-GR 189
           +R  Q +  ++   G F A   A   A     SP R+ R R  P P    R+  Q P G 
Sbjct: 280 ERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGP 339

Query: 190 VLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSE 247
            L  G  S     KS        +G     + GP+L S++ ++     PG   P G++
Sbjct: 340 ALANGFPSAHEALKS-APSSFAPAGKSLCFRPGPALPSTRARQS---FPGPRQPNGAQ 393


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 16/133 (12%)

Query: 166 SPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEER--RTKSWGEQCPETSGTDSGRKGGP 223
           SPRL R   P P P  +S  PP      GA +  R  RT  +G       G  +    GP
Sbjct: 754 SPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYG-------GLPAAPLAGP 806

Query: 224 SLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEI-----DKR 278
           +L + ++ +   PL          A GP+A  R      ++PR G   A        D+R
Sbjct: 807 ALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASS--STPRLGPTPAARAAAPSPDRR 864

Query: 279 GSPTPGTRSCLAP 291
            S +PG    L P
Sbjct: 865 DSASPGAAGGLDP 877



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 37/120 (30%), Positives = 43/120 (35%), Gaps = 20/120 (16%)

Query: 23  GGGPGPSGSETP-----------PPPRRAVLSPGSVFSPGRG-ASFLFPPAESLSPEEPR 70
           GG PG S   TP           PP ++    P     PG G A    PP     P E  
Sbjct: 7   GGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAA 66

Query: 71  SPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRL-RGDRQQVVAAGTLSPPGPEEAKR 129
             GG R   R  +SS G       +S +  S  G   RG+ Q        SP GPE   R
Sbjct: 67  DEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQ-------CSPAGPEGPAR 119


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 101/405 (24%), Positives = 131/405 (32%), Gaps = 56/405 (13%)

Query: 44  PGSVFSPGRGASFLFPPAESLSP---EEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSP 100
           P S +   RG       + S SP   ++ +  GG R  R++    S    GSS       
Sbjct: 144 PASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKK 203

Query: 101 SWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSA 160
               + R DR                ++RK R   R  +  +  +       H ++    
Sbjct: 204 KSVKKHRRDRSD------------SGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRR 251

Query: 161 IQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRT---KSWGEQCPETSGTDS 217
                S   G + SPS     S S+ P R L    R E R+T   +S G + P  SG   
Sbjct: 252 SHRHSS---GSSHSPSLSSHYSDSRSPSR-LSPKHRDEGRKTGSQRSSGSRSPSPSGGSG 307

Query: 218 G----RKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAM 273
                R GG    S Q        PG A     +   PS  VR +K   A+P   +P A 
Sbjct: 308 WGSPQRNGG----SGQRSGAHGGRPGSAHSPPDKPSSPSPRVR-DKAAAAAP---TPPA- 358

Query: 274 EIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRAREL 333
               RG  +P  RS  APS    G     A     R       R    + + P  R R  
Sbjct: 359 ----RGKESPSPRS--APSSQ--GRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRR 410

Query: 334 EDLQPPEALVERQGQFLGSETS--------PAPERGGPRDGEPPGKMGKGYLPCGMPGSG 385
               PP        +   S  S        P PE G  R     GK  K   P   P S 
Sbjct: 411 PRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST 470

Query: 386 EPEVGKR-----PEETTVSVQSAESSDSLSWSRLPRALASVGPEE 425
            P  G       PE  + S        S S SR P    S   E+
Sbjct: 471 SPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK 515



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 27/78 (34%), Positives = 28/78 (35%), Gaps = 4/78 (5%)

Query: 24  GGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLN 83
           GG G    E PP  R A  SP    SPG       P  +S S      P  W S R    
Sbjct: 452 GGHGKRAKERPPRARPASTSP----SPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSK 507

Query: 84  SSSGSGSGSSGSSVSSPS 101
           S S S      S   SPS
Sbjct: 508 SRSRSAEKRPHSPSRSPS 525


>gi|22726201 inositol polyphosphate multikinase [Homo sapiens]
          Length = 416

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 43/200 (21%)

Query: 699 CLDRLMVDVLRPFVPAYHG---DVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEE 755
           C D ++++ LR ++P Y+G         + Y +++D+   F+ PC+MD K+G ++Y    
Sbjct: 98  CFDGVLLE-LRKYLPKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSY---- 152

Query: 756 LTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEG 815
                                DP A    EK Q+ V+K   M+          LG R+  
Sbjct: 153 ---------------------DPFA--SSEKIQQQVSKYPLME----EIGFLVLGMRVYH 185

Query: 816 IKKED-GTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKA-IRTTLEVSPFFKC 873
           +  +   T N+ + ++ T+E + +    F    HN     +D + A I+   ++  +F+ 
Sbjct: 186 VHSDSYETENQHYGRSLTKETIKDGVSRFF---HNGYCLRKDAVAASIQKIEKILQWFEN 242

Query: 874 HEVI---GSSLLFIHDKKEQ 890
            + +    SSLLF+++   Q
Sbjct: 243 QKQLNFYASSLLFVYEGSSQ 262


>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
           [Homo sapiens]
          Length = 1008

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 96/394 (24%), Positives = 147/394 (37%), Gaps = 69/394 (17%)

Query: 10  SLVIMNSANEMKSGGGPGPSG--SETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPE 67
           S V    A+   SG     SG  +ET  P +    +PG       GA  L    E+    
Sbjct: 615 SPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEA-----GAVCL--KKETPQAS 667

Query: 68  EPRSPGGWRSGRRRLNSSSGSGSGSS-GSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEE 126
           E   PG   S R+    +SG G   S G + S+PS   +        V   +L    P  
Sbjct: 668 EKVDPG---SCRKAEPLASGKGEPVSLGKADSAPS--RKTESPSLGKVVPLSLEKTKPSS 722

Query: 127 AKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGR------ARSPSPCPF 180
           + R+L   ++ L + +  +     E  ++ ++  + +  +  LG+          SPCP 
Sbjct: 723 SSRQLD--RKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCP- 779

Query: 181 RSSSQPPGRVLVQGARSEERRTK--SWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLP 238
            +++ PPG       R+ +  TK  SW    P     D+G + G   C S     M P  
Sbjct: 780 EAAAPPPG------PRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSPMSPQD 833

Query: 239 GRAAPTGSEAQGPSAFVRMEKGIPASPRCGSP-----TAMEIDKRGSPT------PGTRS 287
           G          G SAF        A+PR  SP       +++    + T      P T  
Sbjct: 834 G---------AGGSAF-----SFQAAPRAPSPPSRRDAGLQVSLGAAETRSVATGPMTPQ 879

Query: 288 CLAPSLGLFGASLTMATEVAARVTSTGPHRP-QDLALTEPS------GRARELEDL-QPP 339
             AP        +   + +AA V    P  P +D++  E        G A E+E L    
Sbjct: 880 AAAPP-AFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAI 938

Query: 340 EALVERQGQFLGSETSPAPERGGPRDGEPPGKMG 373
           +  +ERQ +  G + +PAP    P     PG+ G
Sbjct: 939 QKHLERQIEEHGRQGAPAPP---PAARAGPGRSG 969


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 106/406 (26%), Positives = 144/406 (35%), Gaps = 77/406 (18%)

Query: 19   EMKSGGGPGPSGSETP---PPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGW 75
            E+ S GG G +    P   P PR A  SP     PGR A+ L     S+  +E   PGG 
Sbjct: 1009 ELSSIGGGGRAARRPPEGHPTPRPA--SP----EPGRVATVL----ASVKHKEAIGPGGE 1058

Query: 76   RSGRRRLNSSSGSG------SGSSGSSVSSP---SWAGRLRGDRQQVVAAGTLSPP-GPE 125
               RRR  S   +G       G   S+   P      GR R        AG   PP    
Sbjct: 1059 VVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKV 1118

Query: 126  EAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQ 185
            EA   L+   R  QN Q N K       I  +S  ++  R P+  + R   P P      
Sbjct: 1119 EASATLKRRIRAKQNQQENVK------FILTESDTVK--RRPK-AKEREAGPEP-----P 1164

Query: 186  PPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTG 245
            PP  V   G  +  RR  S     PE        +  P+  +      +PPLP    P  
Sbjct: 1165 PPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAH-----LPPLP----PPE 1215

Query: 246  SEAQGPSAFVRMEKGIPASPRCGSPTAMEIDK-RGSPTPGTRSCLAPSLGLFGASLTMAT 304
             EA+ P+         P SP+        + K +GSPTP ++    P  G     +  A 
Sbjct: 1216 GEARKPAK-------PPVSPK--PVLTQPVPKLQGSPTPTSKKVPLPGPG--SPEVKRAH 1264

Query: 305  EVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPR 364
                 V+   P  P     T P          +P +A+        G   +P+P R  P 
Sbjct: 1265 GTPPPVSPKPPPPP-----TAP----------KPVKAVAGLPSGSAGPSPAPSPARQPPA 1309

Query: 365  D-GEPPG-KMGKGYLPCGMPGSGEP--EVGKRPEETTVSVQSAESS 406
               +PPG     G  P   P  G P   V  +P     +  +A ++
Sbjct: 1310 ALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAA 1355


>gi|239749835 PREDICTED: hypothetical protein XP_002347183 [Homo
           sapiens]
          Length = 321

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 49/168 (29%), Positives = 67/168 (39%), Gaps = 18/168 (10%)

Query: 344 ERQGQFLGSETSPAPERGG--PRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQ 401
           + +GQ L S    +PE  G   R G+P  +  +  L    PGSGE  V  +  ++TV   
Sbjct: 138 QARGQRLTSRGRESPEATGVPERRGDPETRRNRKSLT---PGSGEFGVRSQSCDSTVP-- 192

Query: 402 SAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTL-----GLLGGS 456
             ES +   W++  +     GP  A      G GRW  +     G+ T        L  +
Sbjct: 193 --ESLERALWAQSSQLAG--GPGLAPRPGASGRGRWVSAPLPPKGTETFFCVLPSALRAA 248

Query: 457 PSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPG 504
            S  P  G  E   P  R L P P    A   + P+CPPG      PG
Sbjct: 249 LSCGPSWG--EDSGPRHRELRPDPDSRRASAERSPRCPPGSPRKAGPG 294


>gi|239744125 PREDICTED: hypothetical protein XP_002343039 [Homo
           sapiens]
          Length = 321

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 49/168 (29%), Positives = 67/168 (39%), Gaps = 18/168 (10%)

Query: 344 ERQGQFLGSETSPAPERGG--PRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQ 401
           + +GQ L S    +PE  G   R G+P  +  +  L    PGSGE  V  +  ++TV   
Sbjct: 138 QARGQRLTSRGRESPEATGVPERRGDPETRRNRKSLT---PGSGEFGVRSQSCDSTVP-- 192

Query: 402 SAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTL-----GLLGGS 456
             ES +   W++  +     GP  A      G GRW  +     G+ T        L  +
Sbjct: 193 --ESLERALWAQSSQLAG--GPGLAPRPGASGRGRWVSAPLPPKGTETFFCVLPSALRAA 248

Query: 457 PSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPG 504
            S  P  G  E   P  R L P P    A   + P+CPPG      PG
Sbjct: 249 LSCGPSWG--EDSGPRHRELRPDPDSRRASAERSPRCPPGSPRKAGPG 294


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 133/620 (21%), Positives = 202/620 (32%), Gaps = 89/620 (14%)

Query: 63   SLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPP 122
            S SP+ P    GW   R          +    S   SP+  GR R   +     G     
Sbjct: 534  SRSPQRP----GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRS--RTPARRGRSRSR 587

Query: 123  GPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRS 182
             P   + + R   R     +   + G   +   A+  +       R  R+RSP+    RS
Sbjct: 588  TPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS 647

Query: 183  SSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGR-------------KGGPSLCSSQ 229
             S+ P R     +R+  RR +S        SG    R             + G S   S 
Sbjct: 648  RSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL 707

Query: 230  VKKGM--PPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKR--------- 278
            V++G      P R   +GS ++      R  K   +  R  S ++ E+ K          
Sbjct: 708  VRRGRSHSRTPQRRGRSGSSSE------RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761

Query: 279  -GSPTPGTRSCLAPSLGLFGAS--LTMATEVAARVTSTGPHRPQDLALTEPSGRARELED 335
              SP    +S L+    L G+S      ++   R + +G  +P+  + T P  R      
Sbjct: 762  LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPP--RRSRSSS 819

Query: 336  LQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPE----VGK 391
              PP+   +   +   S +SP P+    + G PP + G    P     S  P+       
Sbjct: 820  SPPPKQKSKTPSRQSHSSSSPHPK---VKSGTPP-RQGSITSPQANEQSVTPQRRSCFES 875

Query: 392  RPEETTVSVQSAESSDSLSWSRLPRALASVGPEE--ARSGAPVGGGRWQLSDRVEGGSPT 449
             P+    S     S  S S S  PR  +S  P +  +RS +P    +  +S R       
Sbjct: 876  SPDPELKS--RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR----- 928

Query: 450  LGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVW 509
                  S S+ P    V +     R     PC     +++    P     G    +++V 
Sbjct: 929  ----SHSGSSSPSPSRVTSRTTPRRSRSVSPC----SNVESRLLPRYSHSGSSSPDTKVK 980

Query: 510  QGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAV 569
              T  +                   Q       P P++  Q P  P L  + SP   P  
Sbjct: 981  PETPPR-------------------QSHSGSISPYPKVKAQTPPGPSLSGSKSP--CPQE 1019

Query: 570  IITDMGTQE-DGALEETQGSPRGNLPLRK-LSSSSASSTGFSSSYEDSEEDISSDPERTL 627
               D   Q   G+L    G      P       SS    G S +  D   D SS   R  
Sbjct: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079

Query: 628  DPNSAFLHTLDQQKPRVSKS 647
               S  L +  Q  P+  +S
Sbjct: 1080 HSESPSLQSKSQTSPKGGRS 1099



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 68/277 (24%), Positives = 98/277 (35%), Gaps = 58/277 (20%)

Query: 46   SVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGR 105
            SV +PG   S +  P  S   ++P +    +  + R +SSS S S SS SS SS S +  
Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554

Query: 106  LRGDRQQVVAAGTL-------------------------SPPGPEEAKRKLRILQRELQN 140
              G         +L                          PP P  AKRK R       +
Sbjct: 2555 SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614

Query: 141  VQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPC---------PFRSSSQPPGRVL 191
               +       +   + SS+  +  S     + SPSP          P      PPG   
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG--- 2671

Query: 192  VQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMP-PLPGRAAPTGSEAQG 250
                   ERR++S   + P  S  DS      SL  S V++  P P P       S ++ 
Sbjct: 2672 -------ERRSRS--PRKPIDSLRDS-----RSLSYSPVERRRPSPQPSPRDQQSSSSER 2717

Query: 251  PSAFVRMEKGIPASP----RCGSPTAMEIDKRGSPTP 283
             S   R ++G   SP    R  +P+   +  R S +P
Sbjct: 2718 GSR--RGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 74/285 (25%), Positives = 101/285 (35%), Gaps = 55/285 (19%)

Query: 182  SSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRA 241
            SS   P  V   G  S +  +    +  P T      R+   S  S ++K G+P  P R 
Sbjct: 1383 SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS----RERSSSASSPEMKDGLPRTPSRR 1438

Query: 242  APTGSE------AQGPS--AFVRMEKGIPASPRCGSPTAMEIDKRGSP-----TPGTRS- 287
            + +GS       +  PS  +      G+   PR  S    E D    P     TP  RS 
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498

Query: 288  ----------CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQ 337
                      CL P     G+  ++  +  AR           L     SG ++EL D++
Sbjct: 1499 SPSSPELNNKCLTPQRERSGSESSVDQKTVART---------PLGQRSRSGSSQEL-DVK 1548

Query: 338  PPEALVERQGQFLGSETSP-------APERGGPRDGEPPGKMGKGYLPCGMPGSG-EPEV 389
            P  +  ER      S++SP        P R   R G  P    K  L      SG  PEV
Sbjct: 1549 PSASPQERS----ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604

Query: 390  GKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGG 434
              +P       QS   S     +  PRAL    P  +RSG+   G
Sbjct: 1605 KDKP-RAAPRAQSGSDSSPEPKAPAPRAL----PRRSRSGSSSKG 1644



 Score = 37.0 bits (84), Expect = 0.087
 Identities = 75/301 (24%), Positives = 113/301 (37%), Gaps = 48/301 (15%)

Query: 21   KSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPE--EPRSPGGWRSG 78
            +SG  P         P R    S   V    R A    P A+S S    EP++P      
Sbjct: 1578 RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA----PRAQSGSDSSPEPKAPAPRALP 1633

Query: 79   RRRLNSSSGSGSG----SSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRIL 134
            RR  + SS  G G     S S+ SSP    + R  R+     G+ S P P+   R     
Sbjct: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR-----GSRSSPEPKTKSRTPPRR 1688

Query: 135  QRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSP---SPCPF---------RS 182
            +    + ++ +K  +      A SS     R+P   R RSP   SP P          RS
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR-RSPSVSSPEPAEKSRSSRRRRS 1747

Query: 183  SSQPPGRVL-------------VQGARSEERRTKSWGEQCPETSGT--DSGRKGGPSLCS 227
            +S P  +               +Q +RS  RR K+   +  + SG+   + R+   S   
Sbjct: 1748 ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807

Query: 228  SQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDK-RGSPTPGTR 286
            S+V +      G  + + +  +      R  +G   +P    PT+ +  + R SP P  R
Sbjct: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP----PTSRKRSRSRTSPAPWKR 1863

Query: 287  S 287
            S
Sbjct: 1864 S 1864



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 158/690 (22%), Positives = 225/690 (32%), Gaps = 126/690 (18%)

Query: 29   SGSETPPPPRRAVLSPGSVF--SPGRGASFLFPPAESLSPEEPRSPGGWRSGRRR---LN 83
            S S TPP  RR   S   +      R  S L     S S   PR+  G RS  R    + 
Sbjct: 2018 SRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRS-RTPRTARGKRSLTRSPPAIR 2076

Query: 84   SSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGT----------LSP--------PGPE 125
              S SGS S  S  ++P       G R   VA  +          +SP        PG  
Sbjct: 2077 RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGML 2136

Query: 126  EAKRKLRILQRELQN------------VQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRAR 173
            E     R     LQ             +  +Q+  + E H  AQS    A  +  LG AR
Sbjct: 2137 EPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENH--AQSRIALALTAISLGTAR 2194

Query: 174  SPSPCPFRS----SSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQ 229
             P            SQ P  V +   R+      +   + P  S          +L S++
Sbjct: 2195 PPPSMSAAGLAARMSQVPAPVPLMSLRTAP--AANLASRIPAASAA------AMNLASAR 2246

Query: 230  VKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIP-----------ASPRCGSPTAMEIDKR 278
                 P +P   A   ++++ P+A   M    P           A PR  +PTA  ++  
Sbjct: 2247 T----PAIP--TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPR--TPTAPAVNLA 2298

Query: 279  GSPTPGTRSCLA------PSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARE 332
            G+ TP   + L+      P       S +   +  A     GP      A    +G +R 
Sbjct: 2299 GARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAG-SRT 2357

Query: 333  LEDLQPPEALVERQGQFLGSE--TSP-----APERGGPRDGEPPGKMGKGYLPCGMPGSG 385
               L P      R    L     TSP     A ER   R   P     +   P   P   
Sbjct: 2358 AAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417

Query: 386  EPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEG 445
                 + P        S+    + S S LP A      ++ RS  P        SD+   
Sbjct: 2418 RMTSERAPSP------SSRMGQAPSQSLLPPA-----QDQPRSPVPSA-----FSDQSRC 2461

Query: 446  GSPTLGLLGGSPSAQPG---TGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQ 502
                   + GS S   G   T    AG  +G +  P P    + D+ EP    G +   Q
Sbjct: 2462 LIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS-DVGEPPASTGAQ---Q 2517

Query: 503  PGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPE-----LLPQDPDKPFL 557
            P      Q   E+   + +  +   S  +  S    S +  S        LP  P+   L
Sbjct: 2518 PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA-L 2576

Query: 558  RKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPL-RKLSSSSASSTGFSSSYEDSE 616
            ++  SP+  P   + +             G P    P  RK  SSS+SS+  SSS   S 
Sbjct: 2577 KRVPSPTPAPKEAVRE-------------GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623

Query: 617  EDISSDPERTLDPNSAFLHTLDQQKPRVSK 646
               SS    +   +S+   +     P  +K
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653



 Score = 34.3 bits (77), Expect = 0.56
 Identities = 147/686 (21%), Positives = 232/686 (33%), Gaps = 124/686 (18%)

Query: 29   SGSETPP-------PPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRR 81
            SGS +P        PPR++    GS+ SP        PP  SLS  +   P   +S    
Sbjct: 970  SGSSSPDTKVKPETPPRQS--HSGSI-SPYPKVKAQTPPGPSLSGSKSPCPQE-KSKDSL 1025

Query: 82   LNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNV 141
            + S  GS S  +G   S+P           Q+      SP             + +  + 
Sbjct: 1026 VQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH-----------RSDTSSP 1074

Query: 142  QVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQP---------PGRVLV 192
            +V Q      +H ++ S   ++  SP+ GR+RS SP    +S  P            +L 
Sbjct: 1075 EVRQ------SHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128

Query: 193  QGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPS 252
             G   E+ R +S     P         +       S+ K  +PP     A    +    S
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS 1188

Query: 253  AFV---RMEKGI--------PASPRCGSPTAMEIDKRGSPTPGT------RSCLAPSLGL 295
             F    R E  +        P   R G+ ++ E  ++ S  P +         +  S   
Sbjct: 1189 PFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEP 1248

Query: 296  FGASLT-MATEVAARVTSTGPHRPQ-------DLALTEPSGRARELEDLQPPEALVERQG 347
             G  L+ +++E+    TS     P+        L L +   +A  LE ++ P       G
Sbjct: 1249 AGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQA-SLEAVEVPSMASSWGG 1307

Query: 348  QFLGSE-----TSPAPER--GGP---RDGEPPG-KMGKGYLPCGMPGSGEPEVGKRPEET 396
                 E      SP  E   G P   R+  P G +M  G+          P + +   + 
Sbjct: 1308 PHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDP 1367

Query: 397  TVSV--QSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLG 454
            ++ +  QS  SS   S    P A+   G                +S      SP L  + 
Sbjct: 1368 SLDMKEQSTRSSGHSSSELSPDAVEKAG----------------MSSNQSISSPVLDAVP 1411

Query: 455  GSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTME 514
             +PS +       +   S  M + LP   + +           R G  PG  R   GT  
Sbjct: 1412 RTPSRER-----SSSASSPEMKDGLPRTPSRR----------SRSGSSPG-LRDGSGTPS 1455

Query: 515  KAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDM 574
            +  L+ +         T    R + D+ P P+ LPQ P +P  R   SP      +    
Sbjct: 1456 RHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTP-RPRSRSPSSPELNNKCLTPQ- 1513

Query: 575  GTQEDGALEETQGSPRGNLPLRKLSSSSASS----TGFSSSYEDSEEDISSDP------- 623
              +  G+            PL + S S +S        +S  E SE D S D        
Sbjct: 1514 -RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP 1572

Query: 624  --ERTLDPNSAFLHTLDQQKPRVSKS 647
              +R+   +S  + +  +  PR S+S
Sbjct: 1573 LRQRSRSGSSPEVDSKSRLSPRRSRS 1598



 Score = 33.5 bits (75), Expect = 0.96
 Identities = 72/338 (21%), Positives = 113/338 (33%), Gaps = 46/338 (13%)

Query: 163  APRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEER---------RTKSWGEQCPETS 213
            AP   R+   R+PSP       Q P + L+  A+ + R         +++    Q    +
Sbjct: 2413 APSQSRMTSERAPSPSS--RMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA 2470

Query: 214  GTDSGRKGGPSLCSSQV--KKGMPPLPGRAAP--------TGSEAQGPSAFVRMEKGIPA 263
            G+ S   G  +  +S      GM  +P    P          + AQ PSA   ++   PA
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQ---PA 2527

Query: 264  SPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLF----GASLTMATEVAA-RVTSTGPHRP 318
              R  S ++       S +  + S  + S        G+SL +  EVA  RV S  P   
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587

Query: 319  QDLALTEP-------------SGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRD 365
            + +    P             S  +          +          S +S +        
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647

Query: 366  GEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS--VGP 423
               P K G   LP        P   +R       + S   S SLS+S + R   S    P
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707

Query: 424  EEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQP 461
             + +S +   G R     R +  SP+      +PS +P
Sbjct: 2708 RDQQSSSSERGSR--RGQRGDSRSPSHKRRRETPSPRP 2743


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 53/227 (23%), Positives = 74/227 (32%), Gaps = 12/227 (5%)

Query: 23   GGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRL 82
            G  P  +GS  P  P            PG G +F     +S +P+ P      + G    
Sbjct: 2502 GSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTF----EDSGNPKSPDKAQAEQDGAEES 2557

Query: 83   NSSSGSGSGSSGSSVSSPS----WAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQREL 138
             SSS S SGSS SS SS S      G   GD+      GT        + R         
Sbjct: 2558 ESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSS 2617

Query: 139  QNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSE 198
             +   +       +   + SS+  +  S     + S S     SSS             E
Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--SSSTTDE 2675

Query: 199  ERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPL--PGRAAP 243
            +    S  E  P  +   S +   P+  + Q  K  P    PG+  P
Sbjct: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTP 2722



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 85/460 (18%), Positives = 147/460 (31%), Gaps = 69/460 (15%)

Query: 184  SQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAP 243
            ++P   +LV  A+   R+T         +  T  G+ GG +       K      GR   
Sbjct: 2289 AEPSPALLVPSAKRRSRKT---------SKDTGEGKDGGTAGSEEPGAKAR----GRGRK 2335

Query: 244  TGSEAQGPSAFVRMEKG-----IPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGA 298
              ++A+G  A   +E+G     +P++P    P++    K+  P P  +   AP       
Sbjct: 2336 PSAKAKGDRA-ATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPK------ 2388

Query: 299  SLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAP 358
                    A    S  P         EP            P  L+         + + A 
Sbjct: 2389 -----ARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAA 2443

Query: 359  ERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRAL 418
            E  G +    PG+  +  +     G   P+  K  E   +     E   +  W   P++L
Sbjct: 2444 EESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLR----EDPGAGGWQE-PKSL 2498

Query: 419  ASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEP 478
             S+G     +G+      W  +        T G L   P   PG    ++G P       
Sbjct: 2499 LSLGSYPPAAGSSEPKAPWPKA--------TDGDLAQEPG--PGLTFEDSGNP------- 2541

Query: 479  LPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQD 538
                      K P     ++ G +   S     +   +  + +  +G ++EG  E  +  
Sbjct: 2542 ----------KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNG 2591

Query: 539  SDAL-------PSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRG 591
                        +       P       + S S+  +   +   +    +   +  S   
Sbjct: 2592 DGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651

Query: 592  NLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNS 631
            +      SSSS+SS+  SSS  D +   SSD E    P +
Sbjct: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTA 2691



 Score = 33.5 bits (75), Expect = 0.96
 Identities = 66/323 (20%), Positives = 103/323 (31%), Gaps = 56/323 (17%)

Query: 62   ESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSP 121
            E+L   E    GGW+  +  L  S GS   ++GSS     W     GD  Q         
Sbjct: 2479 EALLLREDPGAGGWQEPKSLL--SLGSYPPAAGSSEPKAPWPKATDGDLAQ--------E 2528

Query: 122  PGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFR 181
            PGP                             +  + S    P+SP   +A         
Sbjct: 2529 PGPG----------------------------LTFEDSG--NPKSPDKAQAEQDGAEESE 2558

Query: 182  SSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRA 241
            SSS         G+ S    + S G    ET G + G K G   C +  +         A
Sbjct: 2559 SSSSSS-----SGSSSSSSSSSSSGS---ETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610

Query: 242  APTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLT 301
            +P  S +   S+         +S    S ++       S +  + S  + S     +S +
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670

Query: 302  MATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERG 361
              T+  +  +S     P   A   PS +A        P    ++ G+   S  SP  +  
Sbjct: 2671 STTDEDSSCSSDDEAAPAPTA--GPSAQA------ALPTKATKQAGKARPSAHSPGKKTP 2722

Query: 362  GPRDGEPPGKMGKGYLPCGMPGS 384
             P+   PP +  +   P    G+
Sbjct: 2723 APQPQAPPPQPTQPLQPKAQAGA 2745



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 27/87 (31%), Positives = 32/87 (36%)

Query: 15   NSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGG 74
            +S+    S      SGSET           G   + GR  S     A S +     S   
Sbjct: 2563 SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSS 2622

Query: 75   WRSGRRRLNSSSGSGSGSSGSSVSSPS 101
              S     +SSS S S SS SS SS S
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSS 2649


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 74/296 (25%), Positives = 103/296 (34%), Gaps = 47/296 (15%)

Query: 26   PGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEP--------RSPGGWR- 76
            P     + P  PRR         +PGR      PP  + S   P        RSP   R 
Sbjct: 982  PAARSQQHPSVPRR--------MTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRL 1033

Query: 77   ----SGRRRLNSSSGSGSGSSGSSVSSPSWA------------GRLRGDRQQVVAAGTLS 120
                +GR R  S   S S S   + SS                G    D  +V A    +
Sbjct: 1034 SLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVEAQDVRA 1093

Query: 121  PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF 180
            P     AK     L +  Q V+     G    H   +  A    R  R G  +S +  P 
Sbjct: 1094 PAHAARAKEAAASLPKH-QQVESPTGAGAGGDHRSQRGHAASPARPSRPGGPQSRARVPS 1152

Query: 181  RSS---SQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPL 237
            R++   S+PP +   +   S+ +++ S  +   E +G   G  G   L SS V    P  
Sbjct: 1153 RAAPGKSEPPSK---RPLSSKSQQSVSAEDDEEEDAGFFKG--GKEDLLSSSV----PKW 1203

Query: 238  PGRAAPTGS-EAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPS 292
            P  + P G  +A G  A    E  I  +PR GS   ++      P    R+   PS
Sbjct: 1204 PSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLPPPPGSSPRASHVPS 1259


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 90/398 (22%), Positives = 120/398 (30%), Gaps = 59/398 (14%)

Query: 21  KSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPG------- 73
           K  G P P G    PPP+      G    PG+      PP     P+ P  PG       
Sbjct: 46  KPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPP 103

Query: 74  -GWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPG-PEEAKRKL 131
            G +S  R   S  G   G      + P       G  Q     G   P G P   K + 
Sbjct: 104 QGDKS--RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 161

Query: 132 RILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVL 191
              Q + ++       G  +       +  Q P  P  G+ + P P        PP    
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP-GKPQGPPPQGGNKPQGPPPPGK 220

Query: 192 VQGA------RSEERRTKSWGEQCPETSGTDS--------GRKGGPSLCSSQVKKGMPPL 237
            QG       +S+  R+     Q P   G +         G+  GP        +G PP 
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP- 279

Query: 238 PGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFG 297
           PG+  P G   QG S   R  +  P  P+   P      +   P PG      P  G   
Sbjct: 280 PGK--PQGPPPQGGSK-SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG--- 333

Query: 298 ASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPA 357
                           GP  P       P G ++      PP           G    P 
Sbjct: 334 ------------NKPQGPPPPGKPQGPPPQGGSKSRSARSPP-----------GKPQGPP 370

Query: 358 PERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEE 395
            + G    G PP   G    P   P +G+P+   RP +
Sbjct: 371 QQEGNNPQGPPPPAGGNPQQP-QAPPAGQPQGPPRPPQ 407



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 73/315 (23%), Positives = 99/315 (31%), Gaps = 28/315 (8%)

Query: 206 GEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR----AAPTGSEAQGPSAFVRMEKGI 261
           G   P+   +  G+  GP        +G PP PG+        G++ QGP    + +   
Sbjct: 43  GGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 102

Query: 262 PASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDL 321
           P   +  SP +     +G P  G      P                      GP  P   
Sbjct: 103 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGNKPQGPPPPGKP 159

Query: 322 ALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGM 381
               P G  +      PP        Q       P P  G P+   P G    G  P G 
Sbjct: 160 QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG----GNKPQGP 215

Query: 382 PGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRA-----LASVGPEEARSGAPVGGGR 436
           P  G+P+ G  P+    S QSA S         P+           P + +   P GG +
Sbjct: 216 PPPGKPQ-GPPPQGDNKS-QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 273

Query: 437 WQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPG 496
            Q       G P  G   G P  Q G+ +  +  P G+   P P        + P  PPG
Sbjct: 274 PQ-------GPPPPGKPQG-PPPQGGSKSRSSRSPPGKPQGPPP--QGGNQPQGPPPPPG 323

Query: 497 DRVGVQPGNSRVWQG 511
              G  P      QG
Sbjct: 324 KPQGPPPQGGNKPQG 338



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 66/269 (24%), Positives = 84/269 (31%), Gaps = 44/269 (16%)

Query: 344 ERQGQFLGSETSPAPERGGPRDGEPPGKMGKGY--------------LPCGMPGSGEPEV 389
           E     +      AP +GG +   PP   GK                 P G P    P+ 
Sbjct: 26  EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85

Query: 390 GKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPT 449
           G +P+      +          SR PR+     P     G P  GG     ++ +G  P 
Sbjct: 86  GNKPQGPPPPGKPQGPPPQGDKSRSPRS-----PPGKPQGPPPQGG-----NQPQGPPPP 135

Query: 450 LGLLGGSPSAQPGTGNVEAG-IPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRV 508
            G   G P   P  GN   G  P G+   P P  D     +  + PPG   G  P     
Sbjct: 136 PGKPQGPP---PQGGNKPQGPPPPGKPQGPPPQGD--NKSRSSRSPPGKPQGPPPQGGNQ 190

Query: 509 WQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRK---ACSPSN 565
            QG     G    +  G   +G  + Q       P P   PQ P      K   A SP  
Sbjct: 191 PQGPPPPPG----KPQGPPPQGGNKPQG------PPPPGKPQGPPPQGDNKSQSARSPPG 240

Query: 566 IPAVIITDMGTQEDGALEETQGSPRGNLP 594
            P       G Q  G      G P+G  P
Sbjct: 241 KPQGPPPQGGNQPQGP-PPPPGKPQGPPP 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,414,945
Number of Sequences: 37866
Number of extensions: 2856768
Number of successful extensions: 15674
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 731
Number of HSP's that attempted gapping in prelim test: 12380
Number of HSP's gapped (non-prelim): 3454
length of query: 946
length of database: 18,247,518
effective HSP length: 112
effective length of query: 834
effective length of database: 14,006,526
effective search space: 11681442684
effective search space used: 11681442684
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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