BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194018511 keratin 77 [Homo sapiens] (578 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194018511 keratin 77 [Homo sapiens] 1143 0.0 gi|119395750 keratin 1 [Homo sapiens] 675 0.0 gi|47132620 keratin 2 [Homo sapiens] 633 0.0 gi|119395754 keratin 5 [Homo sapiens] 616 e-176 gi|109148552 keratin 3 [Homo sapiens] 613 e-175 gi|153791670 keratin 76 [Homo sapiens] 597 e-170 gi|5031839 keratin 6A [Homo sapiens] 589 e-168 gi|119703753 keratin 6B [Homo sapiens] 588 e-168 gi|155969697 keratin 6C [Homo sapiens] 586 e-167 gi|109255249 keratin 4 [Homo sapiens] 584 e-167 gi|153791158 keratin 75 [Homo sapiens] 575 e-164 gi|32567786 keratin 6L [Homo sapiens] 562 e-160 gi|28173564 keratin 73 [Homo sapiens] 551 e-157 gi|15618995 keratin 71 [Homo sapiens] 536 e-152 gi|148612803 keratin 6 irs4 [Homo sapiens] 518 e-147 gi|28372503 keratin 72 isoform 1 [Homo sapiens] 506 e-143 gi|226246663 keratin 72 isoform 1 [Homo sapiens] 506 e-143 gi|4504919 keratin 8 [Homo sapiens] 442 e-124 gi|89357932 keratin 5b [Homo sapiens] 437 e-122 gi|67782365 keratin 7 [Homo sapiens] 436 e-122 gi|226246665 keratin 72 isoform 2 [Homo sapiens] 427 e-119 gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 425 e-119 gi|27477127 keratin 82 [Homo sapiens] 372 e-103 gi|4504935 keratin 85 [Homo sapiens] 363 e-100 gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 354 1e-97 gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 352 4e-97 gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 352 4e-97 gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 352 4e-97 gi|14318422 keratin 86 [Homo sapiens] 352 4e-97 gi|169790841 keratin 83 [Homo sapiens] 350 2e-96 >gi|194018511 keratin 77 [Homo sapiens] Length = 578 Score = 1143 bits (2957), Expect = 0.0 Identities = 578/578 (100%), Positives = 578/578 (100%) Query: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS Sbjct: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60 Query: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTS 120 LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTS Sbjct: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTS 120 Query: 121 NFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFID 180 NFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFID Sbjct: 121 NFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFID 180 Query: 181 KVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEV 240 KVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEV Sbjct: 181 KVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEV 240 Query: 241 RSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLK 300 RSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLK Sbjct: 241 RSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLK 300 Query: 301 YLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTK 360 YLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTK Sbjct: 301 YLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTK 360 Query: 361 YQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQA 420 YQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQA Sbjct: 361 YQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQA 420 Query: 421 LQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGE 480 LQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGE Sbjct: 421 LQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGE 480 Query: 481 LQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGS 540 LQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGS Sbjct: 481 LQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGS 540 Query: 541 GCGGGGGSYGGSGRSGRGSSRVQIIQTSTNTSHRRILE 578 GCGGGGGSYGGSGRSGRGSSRVQIIQTSTNTSHRRILE Sbjct: 541 GCGGGGGSYGGSGRSGRGSSRVQIIQTSTNTSHRRILE 578 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 675 bits (1742), Expect = 0.0 Identities = 375/599 (62%), Positives = 452/599 (75%), Gaps = 47/599 (7%) Query: 1 MSHQFSSQSA------FSSMS------RRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGG 48 MS QFSS+S FSS S +R ++SS+ SGGG S CGGGG Sbjct: 1 MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSS-------CGGGG 53 Query: 49 YGIH-GRGFGSRSLYNLGGSRSISINLM--GRSTSGFCQGGGVGGFGGGR----GFGVGS 101 G GFGSRSL NLGGS+SISI++ G SGF G G GGFGGG GFG G Sbjct: 54 GSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGG 113 Query: 102 TGAGGFGG-----GGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPE 156 G GGFGG GGFGG GFG +G GG+GP CPPGGIQEVTINQSLL+PL++E+DPE Sbjct: 114 IGGGGFGGFGSGGGGFGGGGFGGGGYG-GGYGPVCPPGGIQEVTINQSLLQPLNVEIDPE 172 Query: 157 IQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLE 216 IQ++K++EREQI LNN+FASFIDKVRFLEQQNQVLQTKWELLQQV+TST T+NLEP E Sbjct: 173 IQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFE 232 Query: 217 NYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVD 276 ++I +LRR+VD L ++Q R ++E+++MQD+VEDY++KYEDEINKRT +EN+FV +KKDVD Sbjct: 233 SFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVD 292 Query: 277 AAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIID 336 AY++KVDL++++D L E++FL L+ ELSQ+QT IS+TNVILSMDNNRSLDLDSII Sbjct: 293 GAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIA 352 Query: 337 AVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEI 396 V+ QYE IAQ+SK EAE+LYQ+KY+ELQITAGRHGD ++NSK+EI+ELNR +QRL++EI Sbjct: 353 EVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEI 412 Query: 397 SNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVK 456 NVKKQI +Q ISDAE+RGE AL+DA KL DLE+ALQQ+KE+LARLLRDYQ ++ K Sbjct: 413 DNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTK 472 Query: 457 LSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGG---AGGGGSYGSGG--Y 511 L+LD+EIATYR LLEGEESRMSGE +VS+SV S +++GG GGGG YGSGG Y Sbjct: 473 LALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSY 532 Query: 512 GG-----GSGGGYGGGR-SY-RGGGARGRSGGGYGSGCGGGG-GSYGGSGRSG--RGSS 560 G GSGGG GGGR SY GG + G GG YGSG GGGG GSYG SG RG S Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGS 591 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/99 (37%), Positives = 45/99 (45%), Gaps = 10/99 (10%) Query: 24 SAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINLMGRSTSGFC 83 S GSGG S G Y G GGGG+G +G G S GG R S G S+ G Sbjct: 551 SYGSGGSSYGSGGGSYGSGG-GGGGHGSYGSGSSS------GGYRGGSGGGGGGSSGG-- 601 Query: 84 QGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNF 122 +G G GG GG G GS+ G GG F ++ + Sbjct: 602 RGSG-GGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTY 639 Score = 30.8 bits (68), Expect = 3.6 Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 2/53 (3%) Query: 20 STSSSAGSGGGSPAVGSVCYARGRCGGGGYG--IHGRGFGSRSLYNLGGSRSI 70 S SSS G GGS G GGG G I GRG S + + GGS S+ Sbjct: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSV 632 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 633 bits (1632), Expect = 0.0 Identities = 344/577 (59%), Positives = 414/577 (71%), Gaps = 38/577 (6%) Query: 17 RVYSTSSSAGSGGGSPAVGSV-CYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINLM 75 R +S+ S+ SGG + S C +R GGGG+G G GFGSRSL LGG++SISI++ Sbjct: 20 RGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFG--GGGFGSRSLVGLGGTKSISISVA 77 Query: 76 GRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFG------------ 123 G GF GG GG GGG G G G GF GGGFGG GFG FG Sbjct: 78 GGG-GGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136 Query: 124 -LGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKV 182 GGFGP PGGI EV++NQSLL+PL+++VDPEIQ +K QEREQI LNNKFASFIDKV Sbjct: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196 Query: 183 RFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRS 242 RFLEQQNQVLQTKWELLQQ+N T NLEP+ + YI L+R +D L+AE+ QN+E+ + Sbjct: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256 Query: 243 MQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYL 302 MQD+VEDYK KYEDEINKRT +ENDFV LKKDVD AY+ KV+L+S+VD L E+ FLK L Sbjct: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316 Query: 303 FLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQ 362 + E+SQ+ ++DTNVILSMDN+R+LDLDSII V+ QYE IAQRSK+EAEALY +KY+ Sbjct: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376 Query: 363 ELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQ 422 ELQ+T GRHGD LK K+EI+ELNR +QRLQ EI++VKKQ + +Q I+DAE+RGE AL+ Sbjct: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436 Query: 423 DAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQ 482 DA KL DLEEALQQ+KE+LARLLRDYQ ++ VKL+LDVEIATYR+LLEGEE RMSG+L Sbjct: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496 Query: 483 SHVSISVQNSQVSVN-------GGAGGGG------------SYGSGGYGGGSGGGYGGGR 523 S+V++SV +S +S N GG+GG G SYGSGG GS GG GGG Sbjct: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556 Query: 524 SYRGG--GARGRSGGGYGSGCGGGGGSYGGSGRSGRG 558 S GG G+ G SGG YGSG G GGS G G G Sbjct: 557 SISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGG 593 Score = 59.3 bits (142), Expect = 9e-09 Identities = 50/133 (37%), Positives = 58/133 (43%), Gaps = 15/133 (11%) Query: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60 MS SS S S + S +S + GGS GS G YG GR GSR Sbjct: 491 MSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRG 550 Query: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGG-FGGGRGFGVGSTGAGGFGGGG----FGGA 115 GG SI S G+ GGG GG +G G G GS GG+G GG GG Sbjct: 551 --GSGGGGSI-------SGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGG 601 Query: 116 GFGTSNFGLGGFG 128 G S+ G GG+G Sbjct: 602 SRGGSSSG-GGYG 613 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/76 (46%), Positives = 38/76 (50%), Gaps = 2/76 (2%) Query: 498 GGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGS-GCGGGGGSYGGSGRSG 556 G AGG G G GG+GGGS G G G S G G G GG +G G GG G GG G G Sbjct: 84 GAAGGFGGRG-GGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFG 142 Query: 557 RGSSRVQIIQTSTNTS 572 G I + S N S Sbjct: 143 PGGYPGGIHEVSVNQS 158 Score = 45.8 bits (107), Expect = 1e-04 Identities = 39/106 (36%), Positives = 44/106 (41%), Gaps = 33/106 (31%) Query: 487 ISVQNSQVSVNGGAGGGGSYG------------------------SGGYGGGSGGGYGGG 522 +S Q S S G GGGG G GG GGG GGG G Sbjct: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60 Query: 523 RSYRG-GGARGRS------GGGYGS--GCGGGGGSYGGSGRSGRGS 559 RS G GG + S GGG+G+ G GG GG +GG G GS Sbjct: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGS 106 Score = 41.6 bits (96), Expect = 0.002 Identities = 43/124 (34%), Positives = 52/124 (41%), Gaps = 31/124 (25%) Query: 6 SSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVC---YARGRCGGGGYG---------IHG 53 SS +SS S S +GS GGS GS+ Y G GG YG I G Sbjct: 527 SSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISG 586 Query: 54 RGFGSRSLYNL--GGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGG 111 G+GS + GGSR G S+SG GG+G G G GS+ G G Sbjct: 587 GGYGSGGGKHSSGGGSR-------GGSSSG-------GGYGSGGG---GSSSVKGSSGEA 629 Query: 112 FGGA 115 FG + Sbjct: 630 FGSS 633 Score = 37.7 bits (86), Expect = 0.029 Identities = 26/73 (35%), Positives = 30/73 (41%), Gaps = 1/73 (1%) Query: 493 QVSVNGGAGGGGSYGSGGYGGGSGGGYGGGR-SYRGGGARGRSGGGYGSGCGGGGGSYGG 551 Q+S GGG G G+ GS GG R S R GGG G GGG GS Sbjct: 4 QISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSL 63 Query: 552 SGRSGRGSSRVQI 564 G G S + + Sbjct: 64 VGLGGTKSISISV 76 >gi|119395754 keratin 5 [Homo sapiens] Length = 590 Score = 616 bits (1589), Expect = e-176 Identities = 349/593 (58%), Positives = 423/593 (71%), Gaps = 45/593 (7%) Query: 2 SHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSL 61 S FS+ SA + R TS S GGG G V A G CG GGYG SRSL Sbjct: 14 SRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLA-GACGVGGYG-------SRSL 65 Query: 62 YNLGGSRSISINLMG---RSTSGFCQGGGVG-GFGGGRGFGVGSTGAGGFGGGGFGGAGF 117 YNLGGS+ ISI+ G R+ G GGG G G G G GFG G GGFG GG GAGF Sbjct: 66 YNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG--GAGF 123 Query: 118 GTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFAS 177 G FG GF P CPPGGIQEVT+NQSLL PL+L++DP IQR++T+EREQI LNNKFAS Sbjct: 124 G-GGFGGPGF-PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181 Query: 178 FIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQN 237 FIDKVRFLEQQN+VL TKW LLQ+ T T NLEPL E YI +LRRQ+D + E+ R + Sbjct: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241 Query: 238 AEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVN 297 +E+R+MQD+VED+K+KYEDEINKRT +EN+FV+LKKDVDAAY++KV+LE++VD L E+N Sbjct: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301 Query: 298 FLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALY 357 F+K F ELSQ+QTH+SDT+V+LSMDNNR+LDLDSII V+ QYE IA RS+ EAE+ Y Sbjct: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361 Query: 358 QTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERG 417 QTKY+ELQ TAGRHGDDL+N+K EI+E+NR +QRL+AEI NVKKQ +Q+ I+DAE+RG Sbjct: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421 Query: 418 EQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRM 477 E AL+DA KL +LEEALQ++K+++ARLLR+YQ ++ KL+LDVEIATYR+LLEGEE R+ Sbjct: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481 Query: 478 SGELQSHVSISVQNSQVSVNGGAGGGGSYGSG-GYGGGSGGGYGGGRSYRGGGARGRSGG 536 SGE V+ISV S VS YGSG GYGGG GGG GGG GG A G SG Sbjct: 482 SGEGVGPVNISVVTSSVS--------SGYGSGSGYGGGLGGGLGGGLG--GGLAGGSSGS 531 Query: 537 GYGSGCG----GGGGSYGGSG---RSGRG-----------SSRVQIIQTSTNT 571 Y S G GGG S GGSG SGRG SS V+ + T++++ Sbjct: 532 YYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSS 584 >gi|109148552 keratin 3 [Homo sapiens] Length = 628 Score = 613 bits (1582), Expect = e-175 Identities = 353/597 (59%), Positives = 424/597 (71%), Gaps = 57/597 (9%) Query: 14 MSRRVYSTSSSAGSG--------GGSPAVGSVCYARGRCGGGGYGIHGR--GFGSRSLYN 63 MSR+ TS G GS + V ++ G GGG YG GFGSRSLYN Sbjct: 1 MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGG-AGGGAYGFRSGAGGFGSRSLYN 59 Query: 64 LGGSRSISINLM-----------GRSTSGFC----------QGGGVGG-FGGGRGFGVGS 101 LGG++SISI++ GRS+ F GGG GG FGGGRG G G Sbjct: 60 LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119 Query: 102 TGAGGFGG-GGFGGAGF--------GTSNFG-------LGGFGPYCPPGGIQEVTINQSL 145 GAGGFGG GGFGGAG G+ FG GGFGP PGGIQEVTINQSL Sbjct: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179 Query: 146 LEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTS 205 L+PL++E+DP+I ++K QEREQI LNNKFASFIDKVRFLEQQN+VL+TKW LLQQ TS Sbjct: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239 Query: 206 T--GTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTG 263 + GTNNLEPL EN+I LR +D + E+ R ++E+++M+D+VED+K KYEDEINKRT Sbjct: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299 Query: 264 SENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSM 323 +EN+FV LKKDVD+AY++KV+L+++VD L E++FL+ L+ ELSQ+Q+HISDT+V+LSM Sbjct: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359 Query: 324 DNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIA 383 DNNRSLDLDSII VR QYE IAQRSK EAEALYQTK ELQ TAGRHGDDL+N+K EI Sbjct: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419 Query: 384 ELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELA 443 ELNR +QRL+AEI VKKQ +Q+ I++AE+ GE AL+DA KLQ+L+ ALQQ+K++LA Sbjct: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479 Query: 444 RLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGG 503 RLLRDYQ ++ VKL+LDVEIATYR+LLEGEE RMSGE S VSISV +S + + AGG Sbjct: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSS-TTSASAGGY 538 Query: 504 GSYGSGGYGGGSGGGYGGGRSYRGGGARG-RSGGGYGSGCGGGGGSYGGSGRSGRGS 559 G GGYGGG GGG GGG S GG G GGG G G G GGGS G SG SG GS Sbjct: 539 G----GGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGS 591 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/77 (44%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 498 GGAGGGGSYGSGGYGGGSGG--GYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRS 555 GG GGG G G GGG GG G+GG + G G G GG GSG GG GS G G Sbjct: 102 GGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGF 161 Query: 556 GRGSSRVQIIQTSTNTS 572 G G I + + N S Sbjct: 162 GPGGFPGGIQEVTINQS 178 Score = 44.3 bits (103), Expect = 3e-04 Identities = 38/115 (33%), Positives = 44/115 (38%), Gaps = 20/115 (17%) Query: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60 MS + S + S +S S S+ GG +G GGG GRG G Sbjct: 513 MSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGG-- 570 Query: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGA 115 +GG GF GGG GF GG GFG S G GGGF A Sbjct: 571 --GIGG--------------GF--GGGSSGFSGGSGFGSISGARYGVSGGGFSSA 607 >gi|153791670 keratin 76 [Homo sapiens] Length = 638 Score = 597 bits (1538), Expect = e-170 Identities = 341/585 (58%), Positives = 413/585 (70%), Gaps = 42/585 (7%) Query: 2 SHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSL 61 S FS +SA S S R+ + S G+GGG+ C R G FGSRSL Sbjct: 14 SQGFSGRSAVVSGSSRMSCVARSGGAGGGA------CGFRSGAG---------SFGSRSL 58 Query: 62 YNLGGSRSISINLM-----------GRSTSGFC--QGGGV-----GGFGGGRGFGVGSTG 103 YNLG ++SISI++ GRS+ GF GGG GGFGGGRG G G G Sbjct: 59 YNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGG 118 Query: 104 AGGFGG-GGFGGAGF--GTSNF-GLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQR 159 AGGFGG GGFGG G G +F G GGFGP PGGIQEV +NQSLL+PL++E+DP+I + Sbjct: 119 AGGFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQ 178 Query: 160 IKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYI 219 +K QEREQI LNNKFASFIDKVRFLEQQN+VL+TKWELLQQ T +G ++LEP E+YI Sbjct: 179 VKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYI 238 Query: 220 GDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAY 279 L +Q+D L E+ E++SMQD+VED+K KYEDEINKRT +EN+FV LKKDVDAA+ Sbjct: 239 SFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAF 298 Query: 280 VSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVR 339 ++KV+L+++VD+LT EV+FL+ L+ ELSQ+Q+H SDT+V+LSMDNNR LDL SII VR Sbjct: 299 MNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVR 358 Query: 340 TQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNV 399 QYE IAQRSK EAEALYQTK ELQ TAGRHGDDL+N+K EI ELNR +QRL+AEI NV Sbjct: 359 AQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENV 418 Query: 400 KKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSL 459 KKQ +Q+ I++AE+RGE AL+DA KLQDL+ ALQ++K++LARLLRDYQ ++ VKL+L Sbjct: 419 KKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLAL 478 Query: 460 DVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGY 519 DVEIATYR+LLEGEE RMSGE QS V ISV ++ S +G +G G G GSGG Sbjct: 479 DVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYK 538 Query: 520 GG--GRSYRGGGARGRSGGGYG---SGCGGGGGSYGGSGRSGRGS 559 GG S G G G SG GYG SG GG GS G S GS Sbjct: 539 GGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGS 583 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/109 (41%), Positives = 52/109 (47%), Gaps = 11/109 (10%) Query: 475 SRMSGELQSHVSISVQNSQVSVN-GGAGGG-------GSYGSG---GYGGGSGGGYGGGR 523 SR L S+ SIS+ + S GG GGG G YG G YGGG GGG G G Sbjct: 55 SRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGS 114 Query: 524 SYRGGGARGRSGGGYGSGCGGGGGSYGGSGRSGRGSSRVQIIQTSTNTS 572 + G G G +GG G G GG GS+GG G G G I + N S Sbjct: 115 GFGGAGGFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQS 163 >gi|5031839 keratin 6A [Homo sapiens] Length = 564 Score = 589 bits (1519), Expect = e-168 Identities = 329/565 (58%), Positives = 409/565 (72%), Gaps = 24/565 (4%) Query: 13 SMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGG-GYGIHGRGFGSRSLYNLGGSRSIS 71 S SRR +S +S+ G SV +R R GG G G GFGSRSLY LGGS+ IS Sbjct: 12 SSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71 Query: 72 INLMGRSTSGF--CQGGGVGGFGG-GRGFGVGSTGAGGFG-GGGFGGAGFGTSNFGLGGF 127 I + SG + GG GFGG G GFG G GFG GGG G AG G GG Sbjct: 72 IGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG------GFGGP 125 Query: 128 G-PYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLE 186 G P CPPGGIQEVT+NQSLL PL+L++DP IQR++ +EREQI LNNKFASFIDKVRFLE Sbjct: 126 GFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLE 185 Query: 187 QQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDV 246 QQN+VL+TKW LLQ+ T T NLEPL E YI +LRRQ+D + E+ R ++E+R MQD+ Sbjct: 186 QQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDL 245 Query: 247 VEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTE 306 VED+K+KYEDEINKRT +EN+FV LKKDVDAAY++KV+L+++ DTLT E+NFL+ L+ E Sbjct: 246 VEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAE 305 Query: 307 LSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQI 366 LSQ+QTHISDT+V+LSMDNNR+LDLDSII V+ QYE IAQRS+ EAE+ YQTKY+ELQ+ Sbjct: 306 LSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQV 365 Query: 367 TAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQ 426 TAGRHGDDL+N+K EIAE+NR +QRL++EI +VKKQ +Q+ I+DAE+RGE AL+DA Sbjct: 366 TAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKN 425 Query: 427 KLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVS 486 KL+ LE+ALQ++K++LARLL++YQ ++ VKL+LDVEIATYR+LLEGEE R++GE V+ Sbjct: 426 KLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVN 485 Query: 487 ISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGG 546 ISV S VS YG G G GSG G GGG SY G G GGG+ S G Sbjct: 486 ISVVQSTVS--------SGYG-GASGVGSGLGLGGGSSYSYGSGLG-VGGGFSSSSGRAI 535 Query: 547 GSYGGSGRSGRGSSRVQIIQTSTNT 571 G GG G GSS ++ TS+++ Sbjct: 536 G--GGLSSVGGGSSTIKYTTTSSSS 558 >gi|119703753 keratin 6B [Homo sapiens] Length = 564 Score = 588 bits (1515), Expect = e-168 Identities = 329/565 (58%), Positives = 408/565 (72%), Gaps = 24/565 (4%) Query: 13 SMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGG-GYGIHGRGFGSRSLYNLGGSRSIS 71 S SRR +S +S+ G S+ +R R GG G G GFGSRSLY LGGS+ IS Sbjct: 12 SSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71 Query: 72 INLMGRSTSGF--CQGGGVGGFGG-GRGFGVGSTGAGGFG-GGGFGGAGFGTSNFGLGGF 127 I + SG + GG GFGG G GFG G GFG GGG G AG G GG Sbjct: 72 IGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG------GFGGP 125 Query: 128 G-PYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLE 186 G P CPPGGIQEVT+NQSLL PL+L++DP IQR++ +EREQI LNNKFASFIDKVRFLE Sbjct: 126 GFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLE 185 Query: 187 QQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDV 246 QQN+VL TKW LLQ+ T T NLEPL E YI +LRRQ+D + E+ R ++E+R+MQD+ Sbjct: 186 QQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDL 245 Query: 247 VEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTE 306 VED K+KYEDEINKRT +EN+FV LKKDVDAAY++KV+L+++ DTLT E+NFL+ L+ E Sbjct: 246 VEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAE 305 Query: 307 LSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQI 366 LSQ+QTHISDT+V+LSMDNNR+LDLDSII V+ QYE IAQRS+ EAE+ YQTKY+ELQI Sbjct: 306 LSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQI 365 Query: 367 TAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQ 426 TAGRHGDDL+N+K EIAE+NR +QRL++EI +VKKQ +Q+ I+DAE+RGE AL+DA Sbjct: 366 TAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKN 425 Query: 427 KLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVS 486 KL+ LE+ALQ++K++LARLL++YQ ++ VKL+LDVEIATYR+LLEGEE R++GE V+ Sbjct: 426 KLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVN 485 Query: 487 ISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGG 546 ISV S VS YG G G GSG G GGG SY G G GGG+ S G Sbjct: 486 ISVVQSTVS--------SGYG-GASGVGSGLGLGGGSSYSYGSGLG-VGGGFSSSSGRAT 535 Query: 547 GSYGGSGRSGRGSSRVQIIQTSTNT 571 G GG G GSS ++ TS+++ Sbjct: 536 G--GGLSSVGGGSSTIKYTTTSSSS 558 >gi|155969697 keratin 6C [Homo sapiens] Length = 564 Score = 586 bits (1511), Expect = e-167 Identities = 326/565 (57%), Positives = 408/565 (72%), Gaps = 24/565 (4%) Query: 13 SMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGG-GYGIHGRGFGSRSLYNLGGSRSIS 71 S SRR +S +S+ G S+ +R R GG G G GFGSRSLY LGGS+ IS Sbjct: 12 SSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71 Query: 72 INLMGRSTSGF--CQGGGVGGFGG-GRGFGVGSTGAGGFG-GGGFGGAGFGTSNFGLGGF 127 I + SG + GG GFGG G GFG G GFG GGG G AG G GG Sbjct: 72 IGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG------GFGGP 125 Query: 128 G-PYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLE 186 G P CPPGGIQEVT+NQSLL PL+L++DP IQR++ +EREQI LNNKFASFIDKVRFLE Sbjct: 126 GFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLE 185 Query: 187 QQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDV 246 QQN+VL TKW LLQ+ T T NLEPL E YI +LRRQ+D + E+ R ++E+R+MQD+ Sbjct: 186 QQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDL 245 Query: 247 VEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTE 306 VED K+KYEDEINKRT +EN+FV LKKDVDAAY++KV+L+++ DTLT E+NFL+ L+ E Sbjct: 246 VEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAE 305 Query: 307 LSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQI 366 LSQ+QTHISDT+V+LSMDNNR+LDLDSII V+ QYE IAQRS+ EAE+ YQTKY+ELQ+ Sbjct: 306 LSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQV 365 Query: 367 TAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQ 426 TAGRHGDDL+N+K EIAE+NR +QRL++EI +VKKQ +Q+ I+DAE+RGE AL+DA Sbjct: 366 TAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKN 425 Query: 427 KLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVS 486 KL+ LE+ALQ++K++LARLL++YQ ++ VKL+LDVEIATYR+LLEGEE R++GE V+ Sbjct: 426 KLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVN 485 Query: 487 ISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGG 546 +SV S +S YG G G GSG G GGG SY G G GGG+ S G Sbjct: 486 VSVVQSTIS--------SGYG-GASGVGSGLGLGGGSSYSYGSGLG-IGGGFSSSSGRAI 535 Query: 547 GSYGGSGRSGRGSSRVQIIQTSTNT 571 G GG G GSS ++ TS+++ Sbjct: 536 G--GGLSSVGGGSSTIKYTTTSSSS 558 >gi|109255249 keratin 4 [Homo sapiens] Length = 594 Score = 584 bits (1505), Expect = e-167 Identities = 315/521 (60%), Positives = 391/521 (75%), Gaps = 33/521 (6%) Query: 17 RVYSTSSSAGSGGGSPAVGSVCYA--RGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINL 74 R +S S+ GG A SV + GRC GG FGSRSLYNL G++SIS+++ Sbjct: 87 RGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGG-------FGSRSLYNLRGNKSISMSV 139 Query: 75 MGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFG-PYCPP 133 G S G C GG AGGFG GGFGG GFG S G GG G P CP Sbjct: 140 AG-SRQGACFGG-----------------AGGFGTGGFGG-GFGGSFSGKGGPGFPVCPA 180 Query: 134 GGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQ 193 GGIQEVTINQSLL PLH+E+DPEIQ+++T+EREQI +LNNKFASFIDKV+FLEQQN+VL+ Sbjct: 181 GGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLE 240 Query: 194 TKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSK 253 TKW LLQQ T+T + NLEPL E Y+ LR+Q+D L ++ R +E+++MQD VED+K+K Sbjct: 241 TKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTK 300 Query: 254 YEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTH 313 YE+EINKRT +ENDFVVLKKDVDAAY++KV+LE++VD+L E+NFLK L+ ELSQ+QTH Sbjct: 301 YEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTH 360 Query: 314 ISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGD 373 +SDT+V+LSMDNNR+LDLDSII VR QYE IAQRSK EAEALYQTK Q+LQI+ +HGD Sbjct: 361 VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGD 420 Query: 374 DLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEE 433 +LKN+K EIAELNR +QRL+AEI N+KKQ + +Q ++DAE+RGE AL+DA K +LE Sbjct: 421 NLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEA 480 Query: 434 ALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQ 493 ALQQ+KEELAR+LR+YQ ++ VKL+LD+EIATYR+LLEGEE RMSGE QS VSISV + Sbjct: 481 ALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGS 540 Query: 494 VS---VNGGAGGGGSYG-SGGYGGGSGGGYGGGRSYRGGGA 530 S ++GG G G +G S G+G GSG G+G G S G + Sbjct: 541 TSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSS 581 Score = 34.3 bits (77), Expect = 0.32 Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 32/107 (29%) Query: 483 SHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGY-------GGGRSYRGG------- 528 S +S ++ Q V GG G S GS GGG G + G GR GG Sbjct: 69 SSLSAAMIARQQCVRGGPRGF-SCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLY 127 Query: 529 GARGRS---------------GGGYGSGCGGGGGSYGG--SGRSGRG 558 RG GG G G GG GG +GG SG+ G G Sbjct: 128 NLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174 >gi|153791158 keratin 75 [Homo sapiens] Length = 551 Score = 575 bits (1481), Expect = e-164 Identities = 318/578 (55%), Positives = 402/578 (69%), Gaps = 34/578 (5%) Query: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYG---IHGRGFG 57 MS Q S F S SRR +ST+S+ G SV AR G GG G G FG Sbjct: 1 MSRQ--SSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFG 58 Query: 58 SRSLYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGF 117 SRSLYNLGG++ +SIN G S C+ G GG R FGV S GFG GG G GF Sbjct: 59 SRSLYNLGGAKRVSINGCGSS----CRSG-FGGRASNR-FGVNS----GFGYGGGVGGGF 108 Query: 118 GTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFAS 177 +F P CPPGGIQEVT+NQSLL PLHL++DP IQR++ +EREQI LNNKFAS Sbjct: 109 SGPSF------PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFAS 162 Query: 178 FIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQN 237 FIDKVRFLEQQN+VL+TKW LLQ+ + T NLEPL ++Y +LRRQ++ ++ E+ R Sbjct: 163 FIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLE 222 Query: 238 AEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVN 297 AE+R+MQDVVED+K +YEDEINKRT +EN+FV LKKDVDAAY++KV+LE++V +L E+N Sbjct: 223 AELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEIN 282 Query: 298 FLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALY 357 F+ +F ELSQ+QT + DT+V+LSMDNNR+LDLDSII V+ QYE IA RS+ EAE+ Y Sbjct: 283 FIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWY 342 Query: 358 QTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERG 417 QTKY+ELQ+TAGRHGDDL+N+K EI+E+NR +QRL+AEI +VKKQ +Q+ I+DAE+RG Sbjct: 343 QTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRG 402 Query: 418 EQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRM 477 E AL+DA KL DLEEALQ++K+++ARLLR+YQ ++ +KL+LDVEIATYR+LLEGEE R+ Sbjct: 403 ELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRL 462 Query: 478 SGELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGG 537 SGE S V+ISV S +S G G G S G G G G G GY S GG Sbjct: 463 SGEGVSPVNISVVTSTLS--SGYGSGSSIGGGNLGLGGGSGYSFTTS-----------GG 509 Query: 538 YGSGCGGGGGSYGGSGRSGRGSSRVQIIQTSTNTSHRR 575 + G G GG + + G G S + ST +S ++ Sbjct: 510 HSLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQK 547 >gi|32567786 keratin 6L [Homo sapiens] Length = 535 Score = 562 bits (1448), Expect = e-160 Identities = 307/536 (57%), Positives = 383/536 (71%), Gaps = 37/536 (6%) Query: 12 SSMSRRVYST------SSSAGSGGGSPAVGSVCYARGRCGGGGYGIH----GRGFGSRSL 61 SS+SR+ YST +S++G G R G G G H GFGSRSL Sbjct: 3 SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSL 62 Query: 62 YNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSN 121 YNLGG +SIS+++ G G G +GGF GFG F G G G Sbjct: 63 YNLGGHKSISVSVAG----GALLGRALGGF--------------GFGSRAFMGQGAGRQT 104 Query: 122 FGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDK 181 FGP CPPGGIQEVT+NQSLL PLH+E+DPEIQR++TQEREQI LNNKFASFIDK Sbjct: 105 -----FGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159 Query: 182 VRFLEQQNQVLQTKWELLQQVNTSTGT--NNLEPLLENYIGDLRRQVDLLSAEQMRQNAE 239 VRFLEQQN+VL+TKW LLQ+ + G NNLEPL E Y+G +R +D L +E+ R ++E Sbjct: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219 Query: 240 VRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFL 299 +R++QD+VED+K+KYEDEINK T +EN+FVVLKKDVDAAY+ ++DL +V TLT E++FL Sbjct: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279 Query: 300 KYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQT 359 + L+ ELSQVQTH+S+TNV+LSMDNNR+LDLDSII V+ QYELIAQRS+ EAEA YQT Sbjct: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339 Query: 360 KYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQ 419 KY+ELQ+TAG+HGD+L+++K EIAEL RT+QRLQ E KKQ +Q+Q+ I++AE+RGE Sbjct: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399 Query: 420 ALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSG 479 AL+DA +KL DL+ AL Q+KE+L RLLRDYQ ++ VKL+LDVEIATYR+LLE EESRMSG Sbjct: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459 Query: 480 ELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSG 535 E S VSISV + +V G GG S+G G GGSGG GG S G + + G Sbjct: 460 ECPSAVSISVTGNSTTVCG--GGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGG 513 Score = 38.5 bits (88), Expect = 0.017 Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 8/87 (9%) Query: 478 SGELQSHVSISVQNSQVSVNGGAGGGGSYG--SGGYGGGSGGGYGGGRSYR----GGGAR 531 SG S S + VS + G+GGG G +GG+G S GG +S GG Sbjct: 22 SGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVSVAGGALL 81 Query: 532 GRSGGGYGSGCGGGGGSYGGSGRSGRG 558 GR+ GG+G G G G+GR G Sbjct: 82 GRALGGFGFGSRAFMGQ--GAGRQTFG 106 >gi|28173564 keratin 73 [Homo sapiens] Length = 540 Score = 551 bits (1420), Expect = e-157 Identities = 302/535 (56%), Positives = 389/535 (72%), Gaps = 32/535 (5%) Query: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60 MS QF+ +S + ++ +S S+ SGG S + + GG G+ G GF SRS Sbjct: 1 MSRQFTYKSG--AAAKGGFSGCSAVLSGGSSSSYRA----------GGKGLSG-GFSSRS 47 Query: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTS 120 LY+LGG+RSIS N+ S G+ GG GFG G A GF G FG G+ Sbjct: 48 LYSLGGARSISFNVASGS-----------GWAGGYGFGRGR--ASGFAGSMFGSVALGSV 94 Query: 121 NFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFID 180 L CPPGGI +VTIN+SLL PL++E+DPEIQ+++ QEREQI VLNNKFASFID Sbjct: 95 CPSL------CPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFID 148 Query: 181 KVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEV 240 KVRFLEQQNQVL+TKWELLQQ++ + NNLEP+LE YI +LR+Q++ LS +++R ++E+ Sbjct: 149 KVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSEL 208 Query: 241 RSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLK 300 RS+++VVEDYK +YE+EINKRT +EN+FVVLKKDVDAAY SKV+L+++VD L GE+ F K Sbjct: 209 RSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFK 268 Query: 301 YLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTK 360 L+ E +Q+Q+HISDT++ILSMDNNR+LDLDSII VR QYE IA++SK EAEALYQTK Sbjct: 269 CLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTK 328 Query: 361 YQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQA 420 +QELQ+ AGRHGDDLK++K EI+EL R +QRL++EI +VKKQ +++ I+DAE+RG+ A Sbjct: 329 FQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCA 388 Query: 421 LQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGE 480 L+DA KL +LE ALQQ+KEELAR+LR+YQ +L VKLSLD+EIATYR+LLEGEE RMSGE Sbjct: 389 LKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGE 448 Query: 481 LQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSG 535 + VSISV NS ++ G G G + + G G GG S GG SG Sbjct: 449 YTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVSGGYSMLPGGCVTGSG 503 Score = 33.5 bits (75), Expect = 0.55 Identities = 24/64 (37%), Positives = 27/64 (42%), Gaps = 7/64 (10%) Query: 501 GGGGSYGSGGYGGGSGGGYGGGRSYRGGGARG-----RSGGGYGSGCGGGGGSYGGSGRS 555 G SY +GG G GG+ Y GGAR SG G+ G G G G G S Sbjct: 27 GSSSSYRAGGKG--LSGGFSSRSLYSLGGARSISFNVASGSGWAGGYGFGRGRASGFAGS 84 Query: 556 GRGS 559 GS Sbjct: 85 MFGS 88 >gi|15618995 keratin 71 [Homo sapiens] Length = 523 Score = 536 bits (1381), Expect = e-152 Identities = 299/564 (53%), Positives = 392/564 (69%), Gaps = 48/564 (8%) Query: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60 MS QF+ +S + ++ +S S+ SGG S + + G G+ G GFGSRS Sbjct: 1 MSRQFTCKSG--AAAKGGFSGCSAVLSGGSSSSFRA----------GSKGLSG-GFGSRS 47 Query: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTS 120 LY+LGG RS+++ SG G GG+G GRG A GF G FG G Sbjct: 48 LYSLGGVRSLNV------ASG---SGKSGGYGFGRG------RASGFAGSMFGSVALGPV 92 Query: 121 NFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFID 180 CPPGGI +VT+N+SLL PL++E+DPEIQ+++ QEREQI LNNKFASFID Sbjct: 93 ------CPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFID 146 Query: 181 KVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEV 240 KVRFLEQQNQVL+TKWELLQQ++ + NNLEP+LE YI +LR+Q++ LS +++R ++E+ Sbjct: 147 KVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSEL 206 Query: 241 RSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLK 300 R+++DVVEDYK +YE+EINKRT +EN+FV+LKKDVDAAY +KV+L+++V+++ E+ F + Sbjct: 207 RNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFR 266 Query: 301 YLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTK 360 LF E++Q+Q+HISD +VILSMDNNR+LDLDSIID VRTQYE IA +SK EAEALYQTK Sbjct: 267 CLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTK 326 Query: 361 YQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQA 420 +QELQ+ AGRHGDDLKN+K EI+EL R +QR+++EI NVKKQ +++ I+DAE+RG+ A Sbjct: 327 FQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNA 386 Query: 421 LQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGE 480 L+DA KL +LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LLE EE RMSGE Sbjct: 387 LKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGE 446 Query: 481 LQSHVSISVQNSQVSVNGGAGGGGSYG------SGGYGGGSGGGYGGGRSYRGGGARGR- 533 S VSIS+ +S GG YG SGGY S G S RGG R R Sbjct: 447 FPSPVSISIISS-------TSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRG 499 Query: 534 SGGGYGSGCGGGGGSYGGSGRSGR 557 S Y G G S ++ R Sbjct: 500 SANDYKDTLGKGSSLSAPSKKTSR 523 >gi|148612803 keratin 6 irs4 [Homo sapiens] Length = 529 Score = 518 bits (1335), Expect = e-147 Identities = 276/489 (56%), Positives = 356/489 (72%), Gaps = 21/489 (4%) Query: 53 GRGFGSRSLYNLGGSRSISINLMGRSTSGFCQGGGV--GGFGGGRGFGVGSTGAGGFGGG 110 G GFGSRSLY+LGG+R IS N+ G GGV GG+G G G G A GF G Sbjct: 42 GAGFGSRSLYSLGGNRRISFNVAG---------GGVRAGGYGFRPGSGYGGGRASGFAGS 92 Query: 111 GFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMV 170 FG G + + CPPGGI +VT+N+SLL PL++E+DPEIQ+++ QEREQI V Sbjct: 93 MFGSVALGPACLSV------CPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKV 146 Query: 171 LNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLS 230 LN+KFASFIDKVRFLEQQNQVL+TKWELLQQ++ + NLEP+LE YI +LR+Q++ LS Sbjct: 147 LNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLS 206 Query: 231 AEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVD 290 +++R ++E+RSM+D+VEDYK +YE EIN+RT +EN+FVVLKKD DAAY KV+L+++VD Sbjct: 207 GDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVD 266 Query: 291 TLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSK 350 +L E+ FLK L+ E++Q+QTH S+T+VILSMDNNR LDLDSII VR YE IA +SK Sbjct: 267 SLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSK 326 Query: 351 DEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLI 410 EAEALYQTK QELQ+ A RHGDDLK+++ E+ ELNR +QR++ EI NVKKQ +++ I Sbjct: 327 AEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAI 386 Query: 411 SDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLL 470 +DAE+RG+ AL+DA KL +LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LL Sbjct: 387 ADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLL 446 Query: 471 EGEESRMSGELQSHVSISV-QNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGG---GRSYR 526 EGEE RMSGE S VSISV +S S + + G G+ G SG G R Sbjct: 447 EGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSGQTKTTEAR 506 Query: 527 GGGARGRSG 535 GG + G Sbjct: 507 GGDLKDTQG 515 Score = 33.5 bits (75), Expect = 0.55 Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 11/79 (13%) Query: 491 NSQVSVNGGAGGGGSYGSGGYGGGSGGG------YGGGR----SYRGGGARGRSGGGYGS 540 +S V G SY + G G G+G G GG R + GGG R G G+ Sbjct: 19 HSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRA-GGYGFRP 77 Query: 541 GCGGGGGSYGGSGRSGRGS 559 G G GGG G S GS Sbjct: 78 GSGYGGGRASGFAGSMFGS 96 >gi|28372503 keratin 72 isoform 1 [Homo sapiens] Length = 511 Score = 506 bits (1303), Expect = e-143 Identities = 287/551 (52%), Positives = 377/551 (68%), Gaps = 47/551 (8%) Query: 11 FSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSI 70 F R +S S+ SGG + S R R G FGS+SL LGGSRS+ Sbjct: 8 FPRGERLGFSGCSAVLSGGIGSSSASF---RARVKGSA------SFGSKSLSCLGGSRSL 58 Query: 71 SINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPY 130 +++ R GGGR GGF G FG AG G + Sbjct: 59 ALSAAARR-------------GGGR--------LGGFVGTAFGSAGLGPKCPSV------ 91 Query: 131 CPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQ 190 CPPGGI +VT+N+SLL PL++E+DPEIQR++ QEREQI LNNKFASFIDKVRFLEQQNQ Sbjct: 92 CPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 151 Query: 191 VLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDY 250 VL+TKW LLQQ++ + NLEP+ E YI +L++Q+++LS + +R ++E+R+MQD+VEDY Sbjct: 152 VLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDY 211 Query: 251 KSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQV 310 K +YE EIN+RT +EN+FVVLKKDVDAAY++KV+L+++VD+LT E+ F K L+ E++Q+ Sbjct: 212 KKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQI 271 Query: 311 QTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGR 370 Q+HISDT+++LSMDNNR LDLDSII VR QYE IA +SK EAE LYQTK QELQ+TAG+ Sbjct: 272 QSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQ 331 Query: 371 HGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQD 430 HGDDLK +K EI+ELNR +QR+++EI NVKKQ +++ I+DAE+RG+ AL+DA KL + Sbjct: 332 HGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDE 391 Query: 431 LEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQ 490 LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LLE EE RMSGE + VSISV Sbjct: 392 LEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI 451 Query: 491 NSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYG 550 + S N GAGG G S G+G S SY+ A ++ G GS Sbjct: 452 S---STNAGAGGAGF--SMGFGASS------SYSYKTAAADVKTKGSCGSELKDPLAKTS 500 Query: 551 GSGRSGRGSSR 561 GS + + +SR Sbjct: 501 GSSCATKKASR 511 >gi|226246663 keratin 72 isoform 1 [Homo sapiens] Length = 511 Score = 506 bits (1303), Expect = e-143 Identities = 287/551 (52%), Positives = 377/551 (68%), Gaps = 47/551 (8%) Query: 11 FSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSI 70 F R +S S+ SGG + S R R G FGS+SL LGGSRS+ Sbjct: 8 FPRGERLGFSGCSAVLSGGIGSSSASF---RARVKGSA------SFGSKSLSCLGGSRSL 58 Query: 71 SINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPY 130 +++ R GGGR GGF G FG AG G + Sbjct: 59 ALSAAARR-------------GGGR--------LGGFVGTAFGSAGLGPKCPSV------ 91 Query: 131 CPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQ 190 CPPGGI +VT+N+SLL PL++E+DPEIQR++ QEREQI LNNKFASFIDKVRFLEQQNQ Sbjct: 92 CPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 151 Query: 191 VLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDY 250 VL+TKW LLQQ++ + NLEP+ E YI +L++Q+++LS + +R ++E+R+MQD+VEDY Sbjct: 152 VLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDY 211 Query: 251 KSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQV 310 K +YE EIN+RT +EN+FVVLKKDVDAAY++KV+L+++VD+LT E+ F K L+ E++Q+ Sbjct: 212 KKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQI 271 Query: 311 QTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGR 370 Q+HISDT+++LSMDNNR LDLDSII VR QYE IA +SK EAE LYQTK QELQ+TAG+ Sbjct: 272 QSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQ 331 Query: 371 HGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQD 430 HGDDLK +K EI+ELNR +QR+++EI NVKKQ +++ I+DAE+RG+ AL+DA KL + Sbjct: 332 HGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDE 391 Query: 431 LEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQ 490 LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LLE EE RMSGE + VSISV Sbjct: 392 LEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI 451 Query: 491 NSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYG 550 + S N GAGG G S G+G S SY+ A ++ G GS Sbjct: 452 S---STNAGAGGAGF--SMGFGASS------SYSYKTAAADVKTKGSCGSELKDPLAKTS 500 Query: 551 GSGRSGRGSSR 561 GS + + +SR Sbjct: 501 GSSCATKKASR 511 >gi|4504919 keratin 8 [Homo sapiens] Length = 483 Score = 442 bits (1136), Expect = e-124 Identities = 238/465 (51%), Positives = 323/465 (69%), Gaps = 29/465 (6%) Query: 91 FGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLH 150 + G G + S+ G F G G G GG+G GGI VT+NQSLL PL Sbjct: 25 YTSGPGSRISSSSFSRVGSSNFRG-GLG------GGYGGASGMGGITAVTVNQSLLSPLV 77 Query: 151 LEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNN 210 LEVDP IQ ++TQE+EQI LNNKFASFIDKVRFLEQQN++L+TKW LLQQ T+ +N Sbjct: 78 LEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTAR--SN 135 Query: 211 LEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVV 270 ++ + E+YI +LRRQ++ L E+++ AE+ +MQ +VED+K+KYEDEINKRT EN+FV+ Sbjct: 136 MDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVL 195 Query: 271 LKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLD 330 +KKDVD AY++KV+LESR++ LT E+NFL+ L+ E+ ++Q+ ISDT+V+LSMDN+RSLD Sbjct: 196 IKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLD 255 Query: 331 LDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQ 390 +DSII V+ QYE IA RS+ EAE++YQ KY+ELQ AG+HGDDL+ +K EI+E+NR + Sbjct: 256 MDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNIS 315 Query: 391 RLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQ 450 RLQAEI +K Q +++ I+DAE+RGE A++DA KL +LE ALQ++K+++AR LR+YQ Sbjct: 316 RLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQ 375 Query: 451 AMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGGGSYGSGG 510 ++ VKL+LD+EIATYR+LLEGEESR+ +Q ++S+ S G Sbjct: 376 ELMNVKLALDIEIATYRKLLEGEESRLESGMQ---NMSIHTKTTS--------------G 418 Query: 511 YGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRS 555 Y GG YGG S G G +GSG G S S R+ Sbjct: 419 YAGGLSSAYGGLTS---PGLSYSLGSSFGSGAGSSSFSRTSSSRA 460 Score = 33.1 bits (74), Expect = 0.72 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 487 ISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGA--RGRSGGGYGSGCGG 544 +S++ +Q S G ++ S Y G G R G + RG GGGYG G Sbjct: 1 MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGM 60 Query: 545 GG 546 GG Sbjct: 61 GG 62 >gi|89357932 keratin 5b [Homo sapiens] Length = 520 Score = 437 bits (1123), Expect = e-122 Identities = 253/507 (49%), Positives = 330/507 (65%), Gaps = 32/507 (6%) Query: 54 RGFGSRSLYNLGGSRSISINLMGRSTSGFCQGGG-----VGGFGGGRGFGVGSTGAGGFG 108 RGF +RS + S GRS GF GG + FGG GST +G Sbjct: 10 RGFSARS--------ACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGST----WG 57 Query: 109 GGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQI 168 GG G FG + G G CPPGGIQEVTINQ+LL PL +E+DP+ Q ++TQE ++I Sbjct: 58 SGGRLGVRFGEWSGGPGL--SLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEI 115 Query: 169 MVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDL 228 LNN+FASFIDKVRFLEQQN+VL+TKW LLQQ S LEP+ E + LR+Q++ Sbjct: 116 RTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQ 175 Query: 229 LSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESR 288 L E+ +AE+++ +D E+YKSKYE+E ++R ENDFVVLKKDVD ++SK++LE + Sbjct: 176 LQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGK 235 Query: 289 VDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQR 348 ++ L + FLK+L EL Q+QT SDT+V+LSMDNNR LD SII VR +YE IA+ Sbjct: 236 LEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARS 295 Query: 349 SKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQS 408 SK EAEALYQTKYQELQ++A HGD ++ +K++I++L++ +QRLQ++ N+KKQ +Q+ Sbjct: 296 SKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQA 355 Query: 409 LISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQ 468 I+DAE+RGE AL+DA K+ +LE AL+ +K+ LARLL +YQ + KLSLDVEIATYR+ Sbjct: 356 AITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRR 415 Query: 469 LLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGG-GSYGSGGYGGGSGGG------YGG 521 LLEGEE RMSGE S V+IS ++GG GGG GS G G GS G GG Sbjct: 416 LLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGG 475 Query: 522 GRSYRGGG------ARGRSGGGYGSGC 542 G G + SG GS C Sbjct: 476 SNIILGSGKDPVLDSCSVSGSSAGSSC 502 >gi|67782365 keratin 7 [Homo sapiens] Length = 469 Score = 436 bits (1121), Expect = e-122 Identities = 238/438 (54%), Positives = 315/438 (71%), Gaps = 7/438 (1%) Query: 94 GRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPP--GGIQEVTINQSLLEPLHL 151 GRG V + A G G G G S + Y P GI+EVTINQSLL PL L Sbjct: 19 GRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVGAGIREVTINQSLLAPLRL 78 Query: 152 EVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNL 211 + DP +QR++ +E EQI LNNKFASFIDKVRFLEQQN++L+TKW LLQ+ S ++ L Sbjct: 79 DADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQE-QKSAKSSRL 137 Query: 212 EPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVL 271 + E I LR Q++ L + R AE+RSMQDVVED+K+KYEDEIN RT +EN+FVVL Sbjct: 138 PDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVL 197 Query: 272 KKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDL 331 KKDVDAAY+SKV+LE++VD L E+NFL+ L TEL+++Q+ ISDT+V+LSMDN+RSLDL Sbjct: 198 KKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDL 257 Query: 332 DSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQR 391 D II V+ QYE +A+ S+ EAEA YQTK++ LQ AG+HGDDL+N++ EI+E+NR +QR Sbjct: 258 DGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQR 317 Query: 392 LQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQA 451 LQAEI N+K Q ++++ I++AEERGE AL+DA K ++LE ALQ+ K+++AR LR+YQ Sbjct: 318 LQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQE 377 Query: 452 MLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAG----GGGSYG 507 ++ VKL+LD+EIATYR+LLEGEESR++G+ V+ISV NS + G G GG+ G Sbjct: 378 LMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMG 437 Query: 508 SGGYGGGSGGGYGGGRSY 525 S S G G ++Y Sbjct: 438 SNALSFSSSAGPGLLKAY 455 >gi|226246665 keratin 72 isoform 2 [Homo sapiens] Length = 469 Score = 427 bits (1099), Expect = e-119 Identities = 259/551 (47%), Positives = 341/551 (61%), Gaps = 89/551 (16%) Query: 11 FSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSI 70 F R +S S+ SGG + S R R G FGS+SL LGGSRS+ Sbjct: 8 FPRGERLGFSGCSAVLSGGIGSSSASF---RARVKGSA------SFGSKSLSCLGGSRSL 58 Query: 71 SINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPY 130 +++ R GGGR GGF G FG AG G + Sbjct: 59 ALSAAARR-------------GGGR--------LGGFVGTAFGSAGLGPKCPSV------ 91 Query: 131 CPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQ 190 CPPGGI +VT+N+SLL PL++E+DPEIQR++ QEREQI LNNKFASFIDKVRFLEQQNQ Sbjct: 92 CPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 151 Query: 191 VLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDY 250 VL+TKW LLQQ++ + NLEP+ E YI +L++Q+++LS + +R ++E+R+MQD+VEDY Sbjct: 152 VLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDY 211 Query: 251 KSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQV 310 K +YE EIN+RT +EN+FVVLKKDVDAAY++KV+L+++VD+LT E+ F K L+ E++Q+ Sbjct: 212 KKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQI 271 Query: 311 QTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGR 370 Q+HISDT+++LSMDNNR LDLDSII VR QYE IA +SK EAE LYQTK +L+ Sbjct: 272 QSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLE----- 326 Query: 371 HGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQD 430 + I+DAE+RG+ AL+DA KL + Sbjct: 327 -------------------------------------TAIADAEQRGDCALKDARAKLDE 349 Query: 431 LEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQ 490 LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LLE EE RMSGE + VSISV Sbjct: 350 LEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI 409 Query: 491 NSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYG 550 + S N GAGG G S G+G S SY+ A ++ G GS Sbjct: 410 S---STNAGAGGAGF--SMGFGASS------SYSYKTAAADVKTKGSCGSELKDPLAKTS 458 Query: 551 GSGRSGRGSSR 561 GS + + +SR Sbjct: 459 GSSCATKKASR 469 >gi|15431316 keratin, hair, basic, 4 [Homo sapiens] Length = 600 Score = 425 bits (1093), Expect = e-119 Identities = 264/563 (46%), Positives = 353/563 (62%), Gaps = 48/563 (8%) Query: 48 GYGIHGRG-FGSRSLYNLGGSRSISINLMGRST--SGFCQGGGVG-GFGGGRGFGVGST- 102 G G G G FGSRS+ G S S I +G G G G G GFG GRG G+G Sbjct: 41 GPGFRGLGSFGSRSVITFG-SYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRA 99 Query: 103 --------GAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVD 154 GAG G GFGG GFG + +GG G P I VT+N+SLL PL+LE+D Sbjct: 100 DSCVGLGFGAGSGIGYGFGGPGFG---YRVGGVGVPAAPS-ITAVTVNKSLLTPLNLEID 155 Query: 155 PEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPL 214 P QR+K E+EQI LNNKFASFIDKVRFLEQQN++L+TKW LQ+ +NLEPL Sbjct: 156 PNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIR--SNLEPL 213 Query: 215 LENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKD 274 E+YI +LRRQ+++L ++Q R AE +QDV+E +K KYE+E+ R +EN+FV LKKD Sbjct: 214 FESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKD 273 Query: 275 VDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSI 334 VDAA+++K DLE+ VDTLT E++FLK L++ E+ +Q+HIS+T+VI+ MDN+R L+LD I Sbjct: 274 VDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGI 333 Query: 335 IDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQA 394 I V+ QYE +A+RS+ +AEA YQTKY+E+Q+TAG+H D+L+N + EI EL R +QRL+A Sbjct: 334 IAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKA 393 Query: 395 EISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLG 454 EI + K Q ++++ +++AE++GE L DA KL DLE ALQQ+K+++AR L +YQ ++ Sbjct: 394 EIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMN 453 Query: 455 VKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGG-----AGGGGSYGSG 509 KL LD+EIATYR+LLEGEESR+ E V+ISV +S+ + G AG S G Sbjct: 454 AKLGLDIEIATYRRLLEGEESRLC-EGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGV 512 Query: 510 GYGGGSG----GGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSY---------------- 549 + G S G GGAR G G GS Sbjct: 513 TFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPT 572 Query: 550 --GGSGRSGRGSSRVQIIQTSTN 570 G S SG SS V+ + T+T+ Sbjct: 573 QGGFSSCSGGRSSSVRFVSTTTS 595 >gi|27477127 keratin 82 [Homo sapiens] Length = 513 Score = 372 bits (955), Expect = e-103 Identities = 211/437 (48%), Positives = 294/437 (67%), Gaps = 12/437 (2%) Query: 66 GSRSISIN--LMGRSTSGFCQGGGVGGFGGGRGF-GVGSTGAGGFGGGGFGGAGFGTSNF 122 GS+S S +M R + + G GGGRG +G G+ GFG + Sbjct: 13 GSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNVGFGRPRVASRCG 72 Query: 123 G-LGGFG----PYCPPGG-IQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFA 176 G L GFG C P I VTIN+SLL PL LE+DP +QR+K E+EQI LNN+FA Sbjct: 73 GTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFA 132 Query: 177 SFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQ 236 SFI+KVRFLEQ+N++L+TKW +QQ N+EP+ E YI LRRQ+D +S +++R Sbjct: 133 SFINKVRFLEQKNKLLETKWNFMQQQRCCQ--TNIEPIFEGYISALRRQLDCVSGDRVRL 190 Query: 237 NAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEV 296 +E+ S+Q +E YK KYE+E++ R EN+FV LKKDVD A++ K DLE+ + L E+ Sbjct: 191 ESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEI 250 Query: 297 NFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEAL 356 +FLK L+ E+ +Q+ IS+T+VI+ MDN+R LD+D II ++ QY+ IA RSK EAEA Sbjct: 251 DFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAW 310 Query: 357 YQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEER 416 YQ +Y+EL++TAG H D+L+N K EI E+N+ +QRLQ E NVK Q +++ I++AE++ Sbjct: 311 YQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQ 370 Query: 417 GEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESR 476 GE AL DA KL LEEALQ++K+++A LL++YQ ++ KL LD+EIATYR+LLEGEE R Sbjct: 371 GEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHR 430 Query: 477 MSGELQSHVSISVQNSQ 493 + E V+ISV +S+ Sbjct: 431 LC-EGIGPVNISVSSSK 446 >gi|4504935 keratin 85 [Homo sapiens] Length = 507 Score = 363 bits (931), Expect = e-100 Identities = 205/446 (45%), Positives = 294/446 (65%), Gaps = 20/446 (4%) Query: 87 GVGGFGGGRGFGVGSTG----AGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142 G+ GFG +GS G GGF G G + FG + G+ G P C I V++N Sbjct: 47 GLTGFGSRSLCNLGSCGPRIAVGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 101 Query: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202 +SLL PL+LE+DP Q +K +E+EQI LN++FA+FIDKVRFLEQQN++L+TKW+ Q Sbjct: 102 ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ-- 159 Query: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262 N +NLEPL YI LRR+ + + A+ R +E+ +Q+V+E YK KYE+E+ R Sbjct: 160 NQRCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRA 219 Query: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322 +EN+FVVLKKDVD AY+ K DLE+ V+ L E +FL+ L+ E+ +Q HISDT+VI+ Sbjct: 220 TAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVK 279 Query: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382 MDN+R L++D II ++ QY+ +A RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI Sbjct: 280 MDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 339 Query: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442 ELNR +QRL AEI N K Q ++++ +++AE++GE AL DA KL +LE ALQ++K+++ Sbjct: 340 NELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDM 399 Query: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGG 502 A LL++YQ ++ KL LD+EIATYR+LLEGEE R+ + S V++ V +S+ G Sbjct: 400 ACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGS-VNVCVSSSR--------G 450 Query: 503 GGSYGSGGYGGGSGGGYGGGRSYRGG 528 G S G Y G G S GG Sbjct: 451 GVSCGGLSYSTTPGRQITSGPSAIGG 476 >gi|169790853 keratin, hair, basic, 1 [Homo sapiens] Length = 505 Score = 354 bits (909), Expect = 1e-97 Identities = 213/516 (41%), Positives = 312/516 (60%), Gaps = 35/516 (6%) Query: 53 GRGFGSR--SLYNLGGSRSISINLMGRSTSGF-CQGGGVGGFGGGRGFGVGSTGAGGFGG 109 G GFG R S + G R + G C G GGFG + GGF Sbjct: 4 GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGS-------HSVCGGFRA 56 Query: 110 GGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIM 169 G G + FG + G+ G P C I V++N+SLL PL+LE+DP Q +K +E+EQI Sbjct: 57 GSCGRS-FGYRSGGVCGPSPPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIK 111 Query: 170 VLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLL 229 LN++FA+FIDKVRFLEQQN++L+TK + Q N +NLEPL E YI LRR+ + + Sbjct: 112 SLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECV 169 Query: 230 SAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRV 289 A+ R +E+ +Q+V+E YK KYE+E++ R +EN+FV LKKDVD AY+ K DLE+ V Sbjct: 170 EADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANV 229 Query: 290 DTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRS 349 + L E++FL+ L+ E+ +Q+HISDT+V++ +DN+R L++D II ++ QY+ I RS Sbjct: 230 EALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRS 289 Query: 350 KDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSL 409 + EAE+ Y++K +E++ T RHG+ L+ +K EI ELNR +QRL AE+ N K Q ++++ Sbjct: 290 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 349 Query: 410 ISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQL 469 ++ +E++GE AL DA KL +LE ALQ++K+++A L+R+YQ ++ KL LD+EIATYR+L Sbjct: 350 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 409 Query: 470 LEGEESRMSGELQSHVSISVQNSQ-------VSVNGGAGGGGSYGSGGYGGGSGGGYGGG 522 LEGEE R+ + + V++ V +S+ + V+G GS S G G Sbjct: 410 LEGEEQRLCEGIGA-VNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTG-- 466 Query: 523 RSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRSGRG 558 G + CGGG G G S G Sbjct: 467 --------LCAPCGQLNTTCGGGSCGVGSCGISSLG 494 >gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sapiens] Length = 486 Score = 352 bits (904), Expect = 4e-97 Identities = 190/414 (45%), Positives = 283/414 (68%), Gaps = 15/414 (3%) Query: 83 CQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142 C G GGFG + GGF G G + FG + G+ G P C I V++N Sbjct: 37 CYRGLTGGFGS-------HSVCGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 84 Query: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202 +SLL PL+LE+DP Q +K +E+EQI LN++FA+FIDKVRFLEQQN++L+TK + Q Sbjct: 85 ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ-- 142 Query: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262 N +NLEPL E YI LRR+ + + A+ R +E+ +Q+V+E YK KYE+E++ R Sbjct: 143 NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRA 202 Query: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322 +EN+FV LKKDVD AY+ K DLE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++ Sbjct: 203 TAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVK 262 Query: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382 +DN+R L++D II ++ QY+ I RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI Sbjct: 263 LDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 322 Query: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442 ELNR +QRL AE+ N K Q ++++ ++ +E++GE AL DA KL +LE ALQ++K+++ Sbjct: 323 NELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDM 382 Query: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496 A L+R+YQ ++ KL LD+EIATYR+LLEGEE R+ + S V++ V +S+ V Sbjct: 383 ACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS-VNVCVSSSRGGV 435 >gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 486 Score = 352 bits (904), Expect = 4e-97 Identities = 190/414 (45%), Positives = 283/414 (68%), Gaps = 15/414 (3%) Query: 83 CQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142 C G GGFG + GGF G G + FG + G+ G P C I V++N Sbjct: 37 CYRGLTGGFGS-------HSVCGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 84 Query: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202 +SLL PL+LE+DP Q +K +E+EQI LN++FA+FIDKVRFLEQQN++L+TK + Q Sbjct: 85 ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ-- 142 Query: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262 N +NLEPL E YI LRR+ + + A+ R +E+ +Q+V+E YK KYE+E++ R Sbjct: 143 NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRA 202 Query: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322 +EN+FV LKKDVD AY+ K DLE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++ Sbjct: 203 TAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVK 262 Query: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382 +DN+R L++D II ++ QY+ I RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI Sbjct: 263 LDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 322 Query: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442 ELNR +QRL AE+ N K Q ++++ ++ +E++GE AL DA KL +LE ALQ++K+++ Sbjct: 323 NELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDM 382 Query: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496 A L+R+YQ ++ KL LD+EIATYR+LLEGEE R+ + S V++ V +S+ V Sbjct: 383 ACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS-VNVCVSSSRGGV 435 >gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sapiens] Length = 486 Score = 352 bits (904), Expect = 4e-97 Identities = 190/414 (45%), Positives = 283/414 (68%), Gaps = 15/414 (3%) Query: 83 CQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142 C G GGFG + GGF G G + FG + G+ G P C I V++N Sbjct: 37 CYRGLTGGFGS-------HSVCGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 84 Query: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202 +SLL PL+LE+DP Q +K +E+EQI LN++FA+FIDKVRFLEQQN++L+TK + Q Sbjct: 85 ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ-- 142 Query: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262 N +NLEPL E YI LRR+ + + A+ R +E+ +Q+V+E YK KYE+E++ R Sbjct: 143 NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRA 202 Query: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322 +EN+FV LKKDVD AY+ K DLE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++ Sbjct: 203 TAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVK 262 Query: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382 +DN+R L++D II ++ QY+ I RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI Sbjct: 263 LDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 322 Query: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442 ELNR +QRL AE+ N K Q ++++ ++ +E++GE AL DA KL +LE ALQ++K+++ Sbjct: 323 NELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDM 382 Query: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496 A L+R+YQ ++ KL LD+EIATYR+LLEGEE R+ + S V++ V +S+ V Sbjct: 383 ACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS-VNVCVSSSRGGV 435 >gi|14318422 keratin 86 [Homo sapiens] Length = 486 Score = 352 bits (904), Expect = 4e-97 Identities = 190/414 (45%), Positives = 283/414 (68%), Gaps = 15/414 (3%) Query: 83 CQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142 C G GGFG + GGF G G + FG + G+ G P C I V++N Sbjct: 37 CYRGLTGGFGS-------HSVCGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 84 Query: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202 +SLL PL+LE+DP Q +K +E+EQI LN++FA+FIDKVRFLEQQN++L+TK + Q Sbjct: 85 ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ-- 142 Query: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262 N +NLEPL E YI LRR+ + + A+ R +E+ +Q+V+E YK KYE+E++ R Sbjct: 143 NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRA 202 Query: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322 +EN+FV LKKDVD AY+ K DLE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++ Sbjct: 203 TAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVK 262 Query: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382 +DN+R L++D II ++ QY+ I RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI Sbjct: 263 LDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 322 Query: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442 ELNR +QRL AE+ N K Q ++++ ++ +E++GE AL DA KL +LE ALQ++K+++ Sbjct: 323 NELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDM 382 Query: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496 A L+R+YQ ++ KL LD+EIATYR+LLEGEE R+ + S V++ V +S+ V Sbjct: 383 ACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS-VNVCVSSSRGGV 435 >gi|169790841 keratin 83 [Homo sapiens] Length = 493 Score = 350 bits (899), Expect = 2e-96 Identities = 197/452 (43%), Positives = 296/452 (65%), Gaps = 18/452 (3%) Query: 48 GYGIHGRGF--GSRSLYNLGGSRSISINLMGRSTSGF-CQGGGVGGFGGGRGFGVGSTGA 104 G+ G GF G+ S + G R + G C G GGFG + Sbjct: 4 GFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGS-------HSVC 56 Query: 105 GGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQE 164 GGF G G + FG + G+ G P C I V++N+SLL PL+LE+DP Q +K +E Sbjct: 57 GGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEE 111 Query: 165 REQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRR 224 +EQI LN++FA+FIDKVRFLEQQN++L+TK + Q N +NLEPL YI LRR Sbjct: 112 KEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFAGYIETLRR 169 Query: 225 QVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVD 284 + + + A+ R +E+ +Q+V+E YK KYE+E+ R +EN+FV LKKDVD AY+ K D Sbjct: 170 EAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSD 229 Query: 285 LESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYEL 344 LE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++ +DN+R L++D I+ ++ QY+ Sbjct: 230 LEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDD 289 Query: 345 IAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIE 404 IA RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI ELNR +QRL AE+ N K Q Sbjct: 290 IATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNS 349 Query: 405 QMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIA 464 ++++ ++ +E++GE AL DA KL +LE ALQ++K+++A L+R+YQ ++ KL LD+EIA Sbjct: 350 KLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIA 409 Query: 465 TYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496 TYR+LLEGEE R+ +++ V++ V +S+ V Sbjct: 410 TYRRLLEGEEQRLCEGVEA-VNVCVSSSRGGV 440 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.133 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,921,935 Number of Sequences: 37866 Number of extensions: 1267204 Number of successful extensions: 44914 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 678 Number of HSP's successfully gapped in prelim test: 746 Number of HSP's that attempted gapping in prelim test: 10727 Number of HSP's gapped (non-prelim): 14633 length of query: 578 length of database: 18,247,518 effective HSP length: 108 effective length of query: 470 effective length of database: 14,157,990 effective search space: 6654255300 effective search space used: 6654255300 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.