Guide to the Human Genome
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Search of human proteins with 192447432

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|192447432 carbonic anhydrase I [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|192447434 carbonic anhydrase I [Homo sapiens]                      540   e-154
gi|192447432 carbonic anhydrase I [Homo sapiens]                      540   e-154
gi|192447430 carbonic anhydrase I [Homo sapiens]                      540   e-154
gi|4502517 carbonic anhydrase I [Homo sapiens]                        540   e-154
gi|38348436 carbonic anhydrase XIII [Homo sapiens]                    340   1e-93
gi|4557395 carbonic anhydrase II [Homo sapiens]                       323   9e-89
gi|4885099 carbonic anhydrase III [Homo sapiens]                      302   2e-82
gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]            290   9e-79
gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo ...   256   1e-68
gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo ...   246   1e-65
gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]           237   9e-63
gi|22027500 carbonic anhydrase VIII [Homo sapiens]                    196   2e-50
gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo sap...   164   7e-41
gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo sapi...   164   7e-41
gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]            147   1e-35
gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]           136   2e-32
gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]            135   3e-32
gi|130979954 carbonic anhydrase X [Homo sapiens]                      133   2e-31
gi|130979679 carbonic anhydrase X [Homo sapiens]                      133   2e-31
gi|9910366 carbonic anhydrase X [Homo sapiens]                        133   2e-31
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p...   127   1e-29
gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]             117   1e-26
gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]             106   2e-23
gi|194097398 protein tyrosine phosphatase, receptor type, G prec...   100   2e-21
gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]           36   0.030
gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]           36   0.030
gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]           36   0.030
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    29   3.6  
gi|68131557 ankyrin repeat domain 28 [Homo sapiens]                    29   4.7  
gi|157909822 pragmin [Homo sapiens]                                    29   4.7  

>gi|192447434 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  540 bits (1390), Expect = e-154
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60
           MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
Sbjct: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60

Query: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
           INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
Sbjct: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120

Query: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
           VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180

Query: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
           DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
Sbjct: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240

Query: 241 PMQHNNRPTQPLKGRTVRASF 261
           PMQHNNRPTQPLKGRTVRASF
Sbjct: 241 PMQHNNRPTQPLKGRTVRASF 261


>gi|192447432 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  540 bits (1390), Expect = e-154
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60
           MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
Sbjct: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60

Query: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
           INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
Sbjct: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120

Query: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
           VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180

Query: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
           DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
Sbjct: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240

Query: 241 PMQHNNRPTQPLKGRTVRASF 261
           PMQHNNRPTQPLKGRTVRASF
Sbjct: 241 PMQHNNRPTQPLKGRTVRASF 261


>gi|192447430 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  540 bits (1390), Expect = e-154
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60
           MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
Sbjct: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60

Query: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
           INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
Sbjct: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120

Query: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
           VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180

Query: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
           DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
Sbjct: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240

Query: 241 PMQHNNRPTQPLKGRTVRASF 261
           PMQHNNRPTQPLKGRTVRASF
Sbjct: 241 PMQHNNRPTQPLKGRTVRASF 261


>gi|4502517 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  540 bits (1390), Expect = e-154
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60
           MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
Sbjct: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60

Query: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
           INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
Sbjct: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120

Query: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
           VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180

Query: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
           DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
Sbjct: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240

Query: 241 PMQHNNRPTQPLKGRTVRASF 261
           PMQHNNRPTQPLKGRTVRASF
Sbjct: 241 PMQHNNRPTQPLKGRTVRASF 261


>gi|38348436 carbonic anhydrase XIII [Homo sapiens]
          Length = 262

 Score =  340 bits (871), Expect = 1e-93
 Identities = 156/261 (59%), Positives = 202/261 (77%)

Query: 1   MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI 60
           M+   WGY + NGP  W + +PIA+G+ QSP++IKT E K+D+SL+P+S+ Y+P++AK I
Sbjct: 1   MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII 60

Query: 61  INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
            N GHSF+V+F+D +N+SVL+GGP + SYRL Q H HWGS ++HGSEH VDGV Y+AELH
Sbjct: 61  SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH 120

Query: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
           V HWNS KY S  EAA + DGLAV+GV +++GE N +LQK+ D L +IK KGK+  FTNF
Sbjct: 121 VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF 180

Query: 181 DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
           D  +LLP S D+WTYPGSLT PPL ESVTWI+ K+ I++SS+QLA+FRSLL   EG+ A 
Sbjct: 181 DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA 240

Query: 241 PMQHNNRPTQPLKGRTVRASF 261
            +  N+RP QPLKGR VRASF
Sbjct: 241 FLVSNHRPPQPLKGRKVRASF 261


>gi|4557395 carbonic anhydrase II [Homo sapiens]
          Length = 260

 Score =  323 bits (828), Expect = 9e-89
 Identities = 156/259 (60%), Positives = 188/259 (72%), Gaps = 1/259 (0%)

Query: 3   SPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIIN 62
           S  WGY   NGPE W K +PIA G  QSPVDI T   K+D SLKP+SVSY+ AT+  I+N
Sbjct: 2   SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILN 61

Query: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVA 122
            GH+F+V F+D+ +++VLKGGP   +YRL QFHFHWGS +  GSEHTVD  KY+AELH+ 
Sbjct: 62  NGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLV 121

Query: 123 HWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDP 182
           HWN+ KY    +A  + DGLAV+G+ +KVG A P LQKV+D L +IKTKGK A FTNFDP
Sbjct: 122 HWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180

Query: 183 STLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPM 242
             LLP SLD+WTYPGSLT PPL E VTWI+ KE ISVSSEQ+ +FR L  N EG+    M
Sbjct: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM 240

Query: 243 QHNNRPTQPLKGRTVRASF 261
             N RP QPLK R ++ASF
Sbjct: 241 VDNWRPAQPLKNRQIKASF 259


>gi|4885099 carbonic anhydrase III [Homo sapiens]
          Length = 260

 Score =  302 bits (773), Expect = 2e-82
 Identities = 140/257 (54%), Positives = 184/257 (71%), Gaps = 1/257 (0%)

Query: 5   DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVG 64
           +WGY   NGP+ W +L+P A G NQSPV++ T + +HD SL+P SVSY+  +AK I+N G
Sbjct: 4   EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNG 63

Query: 65  HSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHW 124
            +  V F+D  +RS+L+GGP    YRL QFH HWGS+++HGSEHTVDGVKY+AELH+ HW
Sbjct: 64  KTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHW 123

Query: 125 NSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPST 184
           N  KY++  EA  + DG+AVIG+ +K+G  N + Q  LDAL  IKTKGK APFT FDPS 
Sbjct: 124 N-PKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSC 182

Query: 185 LLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQH 244
           L P+  D+WTY GS T PP  E + W++ KE ++VSS+Q+A+ RSLLS+ E +  VP+  
Sbjct: 183 LFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVS 242

Query: 245 NNRPTQPLKGRTVRASF 261
           N RP QP+  R VRASF
Sbjct: 243 NWRPPQPINNRVVRASF 259


>gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]
          Length = 264

 Score =  290 bits (742), Expect = 9e-79
 Identities = 132/256 (51%), Positives = 178/256 (69%)

Query: 6   WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGH 65
           WGY   +GP  W KLYPIA G+ QSP++I +S+  +  SL+P+ +SY    +  I N GH
Sbjct: 7   WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 66

Query: 66  SFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWN 125
           S  V+F D+D+R+V+ GGP    YRL QFHFHWG  ++ GSEHTVDG  + +ELH+ HWN
Sbjct: 67  SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126

Query: 126 SAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTL 185
           + KYS+  EAAS  DGLAV+GV ++ G+ +P + ++ DAL  ++ KG +A F+ F+P  L
Sbjct: 127 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186

Query: 186 LPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHN 245
           LP+S  +WTYPGSLT PPL ESVTWI+ +E I +S  Q+ +FRSLL   E D  + M +N
Sbjct: 187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246

Query: 246 NRPTQPLKGRTVRASF 261
            RP QPLKGR V+ASF
Sbjct: 247 FRPPQPLKGRVVKASF 262


>gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo
           sapiens]
          Length = 317

 Score =  256 bits (654), Expect = 1e-68
 Identities = 121/245 (49%), Positives = 170/245 (69%)

Query: 17  WSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDN 76
           W  +  +  G+ QSP++I+  ++ +D  LKP+++SY+PAT   + N G+SF V FED+ +
Sbjct: 52  WESVDLVPGGDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTD 111

Query: 77  RSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAA 136
           +SV+KGGP   +YRL QFHFHWG+ +  GSEHTVD   + AELH+ HWN+ ++ +  +AA
Sbjct: 112 KSVIKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAA 171

Query: 137 SKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYP 196
            + +GLAVIGV +K+G+ + +LQK++D L +IK K     F +FDPS L+P+  D+WTY 
Sbjct: 172 LEENGLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYS 231

Query: 197 GSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRT 256
           GSLT PPL ESVTWII K+ + V  +QL QFR+LL   EG+    M  N RP QPL  RT
Sbjct: 232 GSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRT 291

Query: 257 VRASF 261
           VR+SF
Sbjct: 292 VRSSF 296


>gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo
           sapiens]
          Length = 305

 Score =  246 bits (629), Expect = 1e-65
 Identities = 124/245 (50%), Positives = 157/245 (64%)

Query: 17  WSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDN 76
           W+    +  G  QSP++I+  ++ +D  LKP+ VSY  A+   I N G+ F V F+D   
Sbjct: 52  WTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATE 111

Query: 77  RSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAA 136
            S + GGP  + YRL QFHFHWG+ NE GSEHTVDG  Y AELH+ HWNS KY +  EA 
Sbjct: 112 ASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAV 171

Query: 137 SKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYP 196
              +GLAVIGV +K+G  +  LQ+++D L  IK K  RA    FDPSTLLP+  D+WTY 
Sbjct: 172 VGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYA 231

Query: 197 GSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRT 256
           GSLT PPL ESVTWII KE + V+  QL+ FR+LL +  G+    M +N RP QPL  R 
Sbjct: 232 GSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRK 291

Query: 257 VRASF 261
           V ASF
Sbjct: 292 VWASF 296


>gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]
          Length = 208

 Score =  237 bits (604), Expect = 9e-63
 Identities = 109/202 (53%), Positives = 144/202 (71%)

Query: 60  IINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAEL 119
           I N GHS  V+F D+D+R+V+ GGP    YRL QFHFHWG  ++ GSEHTVDG  + +EL
Sbjct: 5   ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 64

Query: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTN 179
           H+ HWN+ KYS+  EAAS  DGLAV+GV ++ G+ +P + ++ DAL  ++ KG +A F+ 
Sbjct: 65  HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 124

Query: 180 FDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNA 239
           F+P  LLP+S  +WTYPGSLT PPL ESVTWI+ +E I +S  Q+ +FRSLL   E D  
Sbjct: 125 FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 184

Query: 240 VPMQHNNRPTQPLKGRTVRASF 261
           + M +N RP QPLKGR V+ASF
Sbjct: 185 IHMVNNFRPPQPLKGRVVKASF 206


>gi|22027500 carbonic anhydrase VIII [Homo sapiens]
          Length = 290

 Score =  196 bits (497), Expect = 2e-50
 Identities = 103/268 (38%), Positives = 159/268 (59%), Gaps = 17/268 (6%)

Query: 5   DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAK--EIIN 62
           +WGY++     +W  ++P ANG  QSP+++ + E ++D SL  + +S N    +  E+ N
Sbjct: 28  EWGYEEG---VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTN 84

Query: 63  VGHSFHVNFEDNDNRSVLKGGPFSDS--YRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
            GH+  V  +   ++SVL GGP      + L++  FHWG  N+ GSEHTV+   +  ELH
Sbjct: 85  DGHTIQVILK---SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELH 141

Query: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
           + HWNS  + S+ EA  K  G+A+I + +++G+ +  L+ V + LQ I+ KGK      F
Sbjct: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCF 201

Query: 181 DPSTLLPSSL--DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDN 238
           +P+TLLP  L  D+W Y GSLT PP  E VTWI+ +  +++S  Q+ +FR L ++V+G  
Sbjct: 202 NPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAE 261

Query: 239 AVP-----MQHNNRPTQPLKGRTVRASF 261
            V      +  N RPTQPL  R +RA+F
Sbjct: 262 LVEGCDGILGDNFRPTQPLSDRVIRAAF 289


>gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo
           sapiens]
          Length = 343

 Score =  164 bits (415), Expect = 7e-41
 Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 12/263 (4%)

Query: 6   WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS-YNPATAKEII--N 62
           W Y   +G   WSK YP   G  QSP+D+ +   ++D SL P+    YN +  K+ +  N
Sbjct: 32  WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91

Query: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNE-HGSEHTVDGVKYSAELHV 121
            GHS  +N   + +   L+       Y   Q H HWG+ N+ HGSEHTV G  ++AELH+
Sbjct: 92  NGHSVKLNLPSDMHIQGLQS-----RYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146

Query: 122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFD 181
            H+NS  Y   + A++K++GLAV+ VL+++G  NP   K+   LQ +K KG+ A    F+
Sbjct: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206

Query: 182 PSTLLPS-SLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
              LLP  + +++ Y GSLT PP   +V W + +  + +S EQL    + L     D+  
Sbjct: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266

Query: 241 P--MQHNNRPTQPLKGRTVRASF 261
           P  M +N R  Q    R V  SF
Sbjct: 267 PREMINNFRQVQKFDERLVYTSF 289


>gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo
           sapiens]
          Length = 354

 Score =  164 bits (415), Expect = 7e-41
 Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 12/263 (4%)

Query: 6   WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVS-YNPATAKEII--N 62
           W Y   +G   WSK YP   G  QSP+D+ +   ++D SL P+    YN +  K+ +  N
Sbjct: 32  WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 91

Query: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNE-HGSEHTVDGVKYSAELHV 121
            GHS  +N   + +   L+       Y   Q H HWG+ N+ HGSEHTV G  ++AELH+
Sbjct: 92  NGHSVKLNLPSDMHIQGLQS-----RYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 146

Query: 122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFD 181
            H+NS  Y   + A++K++GLAV+ VL+++G  NP   K+   LQ +K KG+ A    F+
Sbjct: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 206

Query: 182 PSTLLPS-SLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
              LLP  + +++ Y GSLT PP   +V W + +  + +S EQL    + L     D+  
Sbjct: 207 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 266

Query: 241 P--MQHNNRPTQPLKGRTVRASF 261
           P  M +N R  Q    R V  SF
Sbjct: 267 PREMINNFRQVQKFDERLVYTSF 289


>gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]
          Length = 337

 Score =  147 bits (370), Expect = 1e-35
 Identities = 89/262 (33%), Positives = 130/262 (49%), Gaps = 11/262 (4%)

Query: 6   WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDT---SLKPISVSYNPATAKEIIN 62
           W Y+  +G + W   YP    N QSP+DI+T     D    +L+P           ++ N
Sbjct: 22  WTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHN 81

Query: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHG-SEHTVDGVKYSAELHV 121
            GH+  ++       S L  G     Y   Q H HWG     G SEH ++     AELH+
Sbjct: 82  NGHTVQLSLP-----STLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHI 136

Query: 122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA-NPKLQKVLDALQAIKTKGKRAPFTNF 180
            H++S  Y SL+EAA +  GLAV+G+L++VGE  N   + +L  L  ++ K ++     F
Sbjct: 137 VHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPF 196

Query: 181 DPSTLLPSSL-DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNA 239
           +   LLP  L  ++ Y GSLT PP Y+SV W +      +S EQL + +  L + E + +
Sbjct: 197 NLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPS 256

Query: 240 VPMQHNNRPTQPLKGRTVRASF 261
             +  N R  QPL  R V ASF
Sbjct: 257 KLLVQNYRALQPLNQRMVFASF 278


>gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]
          Length = 459

 Score =  136 bits (343), Expect = 2e-32
 Identities = 86/261 (32%), Positives = 131/261 (50%), Gaps = 16/261 (6%)

Query: 6   WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISV---SYNPATAKEIIN 62
           W Y    G   W ++ P   G  QSPVDI+        +L+P+ +      P     + N
Sbjct: 141 WRY---GGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRN 197

Query: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVA 122
            GHS  +        ++   GP  + YR  Q H HWG+    GSEHTV+G ++ AE+HV 
Sbjct: 198 NGHSVQLTLPPGLEMAL---GPGRE-YRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVV 253

Query: 123 HWNSAKYSSLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGKRAPFTNFD 181
           H ++A ++ + EA  +  GLAV+   ++ G E N   +++L  L+ I  +G        D
Sbjct: 254 HLSTA-FARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLD 312

Query: 182 PSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240
            S LLPS    ++ Y GSLT PP  + V W +  +++ +S++QL    +L   + G    
Sbjct: 313 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQL---HTLSDTLWGPGDS 369

Query: 241 PMQHNNRPTQPLKGRTVRASF 261
            +Q N R TQPL GR + ASF
Sbjct: 370 RLQLNFRATQPLNGRVIEASF 390


>gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]
          Length = 308

 Score =  135 bits (341), Expect = 3e-32
 Identities = 88/266 (33%), Positives = 136/266 (51%), Gaps = 18/266 (6%)

Query: 5   DWGYDDKNGPE-QWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE--II 61
           DW Y +    E  W + YP   G  QSP++++ ++ +++ SLK ++++     A E  ++
Sbjct: 22  DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81

Query: 62  NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEH--GSEHTVDGVKYSAEL 119
           N GH+  ++       +V  G      Y   Q HFHWG  +    GSEHTVDG+++  E+
Sbjct: 82  NNGHTVQISLPSTMRMTVADG----TVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137

Query: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--ANPKLQKVLDALQAIKTKGKRAPF 177
           H+ H+NS KY S   A    DGLAV+   ++V     N      +  L  IK  G+R   
Sbjct: 138 HIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196

Query: 178 TNFDPSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEG 236
           T  D   +LP +L  ++TY GSLT PP  E+V W +  + + +S  Q+ +    L N   
Sbjct: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK----LENSLL 252

Query: 237 DNAVPMQHNN-RPTQPLKGRTVRASF 261
           D+     HN+ R TQPL  R V ++F
Sbjct: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278


>gi|130979954 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  133 bits (334), Expect = 2e-31
 Identities = 78/240 (32%), Positives = 124/240 (51%), Gaps = 7/240 (2%)

Query: 26  GNNQSPVDIKTSETKHDTSLKPISVSYNPATAK-EIINVGHSFHVNFE-DNDNRSVLKGG 83
           G  QSPV+I+TS    D  L P+ ++         + N G   HV+   D ++   + GG
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGR--HVSLRLDKEHLVNISGG 120

Query: 84  PFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLA 143
           P + S+RL +   H+GS +  GSEH ++G  +S E+ + H+N   Y+++ EAA   +GL 
Sbjct: 121 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV 180

Query: 144 VIGVLMKVGE-ANPKLQKVL--DALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLT 200
           V+ + +KV + +NP L ++L  D +  I  K         +   L P +  F TY GS+T
Sbjct: 181 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT 240

Query: 201 HPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRAS 260
            PP YE+ +WII  + + ++  Q+   R L  N      + M  N RP QPL  R +R +
Sbjct: 241 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN 300


>gi|130979679 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  133 bits (334), Expect = 2e-31
 Identities = 78/240 (32%), Positives = 124/240 (51%), Gaps = 7/240 (2%)

Query: 26  GNNQSPVDIKTSETKHDTSLKPISVSYNPATAK-EIINVGHSFHVNFE-DNDNRSVLKGG 83
           G  QSPV+I+TS    D  L P+ ++         + N G   HV+   D ++   + GG
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGR--HVSLRLDKEHLVNISGG 120

Query: 84  PFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLA 143
           P + S+RL +   H+GS +  GSEH ++G  +S E+ + H+N   Y+++ EAA   +GL 
Sbjct: 121 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV 180

Query: 144 VIGVLMKVGE-ANPKLQKVL--DALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLT 200
           V+ + +KV + +NP L ++L  D +  I  K         +   L P +  F TY GS+T
Sbjct: 181 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT 240

Query: 201 HPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRAS 260
            PP YE+ +WII  + + ++  Q+   R L  N      + M  N RP QPL  R +R +
Sbjct: 241 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN 300


>gi|9910366 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  133 bits (334), Expect = 2e-31
 Identities = 78/240 (32%), Positives = 124/240 (51%), Gaps = 7/240 (2%)

Query: 26  GNNQSPVDIKTSETKHDTSLKPISVSYNPATAK-EIINVGHSFHVNFE-DNDNRSVLKGG 83
           G  QSPV+I+TS    D  L P+ ++         + N G   HV+   D ++   + GG
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGR--HVSLRLDKEHLVNISGG 120

Query: 84  PFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLA 143
           P + S+RL +   H+GS +  GSEH ++G  +S E+ + H+N   Y+++ EAA   +GL 
Sbjct: 121 PMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLV 180

Query: 144 VIGVLMKVGE-ANPKLQKVL--DALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLT 200
           V+ + +KV + +NP L ++L  D +  I  K         +   L P +  F TY GS+T
Sbjct: 181 VVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMT 240

Query: 201 HPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRAS 260
            PP YE+ +WII  + + ++  Q+   R L  N      + M  N RP QPL  R +R +
Sbjct: 241 IPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTN 300


>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
           precursor [Homo sapiens]
          Length = 2315

 Score =  127 bits (319), Expect = 1e-29
 Identities = 83/266 (31%), Positives = 136/266 (51%), Gaps = 13/266 (4%)

Query: 6   WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE---IIN 62
           W Y      + W K YP  N   QSP++I    T+ + +LK +       T+ E   I N
Sbjct: 38  WSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENTFIHN 97

Query: 63  VGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTN--EHGSEHTVDGVKYSAELH 120
            G +  +N   ND R  + GG     ++  +  FHWG  N    GSEH+++G K+  E+ 
Sbjct: 98  TGKTVEINLT-NDYR--VSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQ 154

Query: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGKRAPFTN 179
           +  +++ ++SS  EA      L  + +L +VG E N   + ++D ++++   GK+A    
Sbjct: 155 IYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAALDP 214

Query: 180 FDPSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDN 238
           F    LLP+S D ++ Y GSLT PP  ++V WI+ K+++S+S  QLA F  +L+  +   
Sbjct: 215 FILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGY 274

Query: 239 AVPM---QHNNRPTQPLKGRTVRASF 261
            + M   Q+N R  Q    R V +S+
Sbjct: 275 VMLMDYLQNNFREQQYKFSRQVFSSY 300


>gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]
          Length = 328

 Score =  117 bits (293), Expect = 1e-26
 Identities = 81/270 (30%), Positives = 128/270 (47%), Gaps = 17/270 (6%)

Query: 6   WGYDDK------NGPEQWSKLYPI----ANGNNQSPVDIKTSETKHDTSLKPISVSYNPA 55
           W Y D        GP  W  +       A G  QSPVD++     +D  L P+ +S    
Sbjct: 35  WSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGE 94

Query: 56  TAK-EIINVGHSFHVNFEDNDNRSV-LKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGV 113
             +  + N G   HV+F       V + GGP   S+RL +    +G+ +  GSEH ++  
Sbjct: 95  KLRGTLYNTGR--HVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQ 152

Query: 114 KYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE-ANPKLQKVL--DALQAIKT 170
            +SAE+ + H+N   Y + + A+   +GLA++ + + V   +NP L ++L  D +  I  
Sbjct: 153 GFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISY 212

Query: 171 KGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230
           K       +     L P S  F TY GSL+ PP  E+VTWI+   +++++S Q+   R L
Sbjct: 213 KNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLL 272

Query: 231 LSNVEGDNAVPMQHNNRPTQPLKGRTVRAS 260
             N        +  N+RP QPL  R +R +
Sbjct: 273 SQNPPSQIFQSLSGNSRPLQPLAHRALRGN 302


>gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]
          Length = 312

 Score =  106 bits (265), Expect = 2e-23
 Identities = 80/267 (29%), Positives = 120/267 (44%), Gaps = 15/267 (5%)

Query: 2   ASPDWGYDDKNGPEQWSKLYPIANGNN-----QSPVDIKTSETKHDTSLKPISVS-YNPA 55
           A   W Y+ +     +  L P+  G N     QSP++I T++ K D  L     S Y+  
Sbjct: 19  AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKK 78

Query: 56  TAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKY 115
               + N GHS  +  E   N++ + GG     Y+  Q H HW      GSEH++DG  +
Sbjct: 79  QTWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHF 135

Query: 116 SAELHVAHWNSAKYS-SLAEAASKADGLAVIGVLMKVG-EANPKLQKVLDALQAIKTKGK 173
           + E+H+ H      S ++ EA    D +AV+  L++ G + N   Q +++AL  I     
Sbjct: 136 AMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEM 195

Query: 174 RAPFTNFDPSTLLPSS---LDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSL 230
                      LLP       ++ Y GSLT P   E V W + +E I +  EQ+  F   
Sbjct: 196 STTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQK 255

Query: 231 LSNVEGDNAVPMQHNNRPTQPLKGRTV 257
           L   + +  V M+ N RP Q L  RTV
Sbjct: 256 L-YYDKEQTVSMKDNVRPLQQLGQRTV 281


>gi|194097398 protein tyrosine phosphatase, receptor type, G
           precursor [Homo sapiens]
          Length = 1445

 Score =  100 bits (248), Expect = 2e-21
 Identities = 70/266 (26%), Positives = 120/266 (45%), Gaps = 12/266 (4%)

Query: 4   PDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSY--NPATAKEII 61
           P W Y    GPE W        G +QSP+DI     +     + + +    N ++ K  +
Sbjct: 58  PYWAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWM 117

Query: 62  -NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTN-EHGSEHTVDGVKYSAEL 119
            N G +  +  +D+     + G      ++  +  FHWG +N   GSEH+++G ++  E+
Sbjct: 118 KNTGKTVAILLKDD---YFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEM 174

Query: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA-NPKLQKVLDALQAIKTKGKRAPFT 178
            +  +N   + S   A S+   +  + +  +V    N  L  ++  L+ +    K     
Sbjct: 175 QIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLD 234

Query: 179 NFDPSTLLPSSL-DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGD 237
            F    LLP+SL  ++ Y GSLT PP  E V WI+ +  + +S  QL  F S+ +  + D
Sbjct: 235 PFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQD 294

Query: 238 NAVPMQH---NNRPTQPLKGRTVRAS 260
           +   +++   N RP Q L  R V  S
Sbjct: 295 HVKSVEYLRNNFRPQQRLHDRVVSKS 320


>gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 36.2 bits (82), Expect = 0.030
 Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)

Query: 117 AELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA-NPKLQKVLDALQ--AIKTKGK 173
           +++HV H N+ KY S+ EA    DGL       +     +P  ++        AI +  +
Sbjct: 21  SKMHVVHSNT-KYQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLR 79

Query: 174 RAP-----FTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFR 228
           + P      + F  +++ P++  +  + GSLT P    +V W + ++ I +   Q+  F 
Sbjct: 80  KVPEPVNLMSTFPLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMTLFY 139

Query: 229 SL 230
           +L
Sbjct: 140 TL 141


>gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 36.2 bits (82), Expect = 0.030
 Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)

Query: 117 AELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA-NPKLQKVLDALQ--AIKTKGK 173
           +++HV H N+ KY S+ EA    DGL       +     +P  ++        AI +  +
Sbjct: 21  SKMHVVHSNT-KYQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLR 79

Query: 174 RAP-----FTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFR 228
           + P      + F  +++ P++  +  + GSLT P    +V W + ++ I +   Q+  F 
Sbjct: 80  KVPEPVNLMSTFPLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMTLFY 139

Query: 229 SL 230
           +L
Sbjct: 140 TL 141


>gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 36.2 bits (82), Expect = 0.030
 Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)

Query: 117 AELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA-NPKLQKVLDALQ--AIKTKGK 173
           +++HV H N+ KY S+ EA    DGL       +     +P  ++        AI +  +
Sbjct: 21  SKMHVVHSNT-KYQSMEEAPRHGDGLECRPCCWRTPRTWSPSQEQDCSNTNFCAIVSGLR 79

Query: 174 RAP-----FTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFR 228
           + P      + F  +++ P++  +  + GSLT P    +V W + ++ I +   Q+  F 
Sbjct: 80  KVPEPVNLMSTFPLASMRPNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMTLFY 139

Query: 229 SL 230
           +L
Sbjct: 140 TL 141


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 29.3 bits (64), Expect = 3.6
 Identities = 14/48 (29%), Positives = 23/48 (47%)

Query: 14  PEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEII 61
           P++ +K+ P    NN SP    T   K DT     +++Y  +T+   I
Sbjct: 115 PKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQI 162


>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
          Length = 1053

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 27/121 (22%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 50  VSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHF-HWGSTN------ 102
           ++ N   A+ +I+   +  VN  D+  R+ L    F+D     Q    H    N      
Sbjct: 797 INDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTG 856

Query: 103 --------EHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA 154
                   E+G  +TV+ +  SA   +   +++K ++L  A SK    + + +L K+ + 
Sbjct: 857 KTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDR 916

Query: 155 N 155
           N
Sbjct: 917 N 917


>gi|157909822 pragmin [Homo sapiens]
          Length = 1402

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 37/146 (25%), Positives = 57/146 (39%), Gaps = 24/146 (16%)

Query: 1   MASPDWGYDDKNGPEQ------WSKLYPIANGNNQ-SPVDIKTSET--------KHDTSL 45
           + S  WG + KNGP        W +L+P    + Q S V    S++        K  + +
Sbjct: 647 LLSHSWGRETKNGPTDHSNSTTWHRLHPTDGSSGQNSKVGTGMSKSASFAFEFPKDRSGI 706

Query: 46  KPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGG--PFSDSYRLFQFHFHWGSTNE 103
           +  S    P  ++      H   +N   +D   V +G     S S+R     F  GST+ 
Sbjct: 707 ETFSPPPPPPKSR------HLLKMNKSSSDLEKVSQGSAESLSPSFRGVHVSFTTGSTDS 760

Query: 104 HGSE-HTVDGVKYSAELHVAHWNSAK 128
             S+  T      S+EL  +  NS K
Sbjct: 761 LASDSRTCSDGGPSSELAHSPTNSGK 786


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,460,222
Number of Sequences: 37866
Number of extensions: 438931
Number of successful extensions: 746
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 670
Number of HSP's gapped (non-prelim): 45
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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