Search of human proteins with 191250775

Search of human proteins with 191250775

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|191250775 spire homolog 1 isoform c [Homo sapiens]
         (622 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|191250771 spire homolog 1 isoform b [Homo sapiens]                1242   0.0  
gi|191250775 spire homolog 1 isoform c [Homo sapiens]                1242   0.0  
gi|191250773 spire homolog 1 isoform a [Homo sapiens]                1233   0.0  
gi|55749600 spire homolog 2 [Homo sapiens]                            454   e-127
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     42   0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        41   0.004
gi|58082089 hypothetical protein LOC161394 [Homo sapiens]              40   0.005
gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog...    40   0.008
gi|61966703 NHS-like 2 [Homo sapiens]                                  40   0.008
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    39   0.014
gi|61966919 hypothetical protein LOC442444 [Homo sapiens]              39   0.014
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    39   0.019
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   38   0.024
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   38   0.024
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   38   0.024
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    38   0.024
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora...    38   0.032
gi|110349719 titin isoform N2-A [Homo sapiens]                         37   0.054
gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]         37   0.054
gi|114431248 hypothetical protein LOC205717 [Homo sapiens]             37   0.071
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    37   0.071
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    37   0.071
gi|226371669 discs large homolog 7 isoform b [Homo sapiens]            37   0.071
gi|226371667 discs large homolog 7 isoform a [Homo sapiens]            37   0.071
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               36   0.093
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         36   0.093
gi|38373677 guanine nucleotide-releasing factor 2 isoform b [Hom...    36   0.12 
gi|38373675 guanine nucleotide-releasing factor 2 isoform a [Hom...    36   0.12 
gi|68508961 centromere protein C 1 [Homo sapiens]                      36   0.12 
gi|41281612 zinc finger protein 828 [Homo sapiens]                     36   0.12 

>gi|191250771 spire homolog 1 isoform b [Homo sapiens]
          Length = 742

 Score = 1242 bits (3214), Expect = 0.0
 Identities = 622/622 (100%), Positives = 622/622 (100%)

Query: 1   METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 60
           METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
Sbjct: 121 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 180

Query: 61  LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 120
           LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
Sbjct: 181 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 240

Query: 121 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 180
           AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
Sbjct: 241 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 300

Query: 181 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 240
           YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
Sbjct: 301 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 360

Query: 241 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQ 300
           PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQ
Sbjct: 361 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQ 420

Query: 301 TKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAV 360
           TKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAV
Sbjct: 421 TKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAV 480

Query: 361 STRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVE 420
           STRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVE
Sbjct: 481 STRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVE 540

Query: 421 CLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFC 480
           CLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFC
Sbjct: 541 CLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFC 600

Query: 481 KRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSS 540
           KRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSS
Sbjct: 601 KRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSS 660

Query: 541 KSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQ 600
           KSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQ
Sbjct: 661 KSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQ 720

Query: 601 SFYMSSPGPSEYCPSERTISEI 622
           SFYMSSPGPSEYCPSERTISEI
Sbjct: 721 SFYMSSPGPSEYCPSERTISEI 742


>gi|191250775 spire homolog 1 isoform c [Homo sapiens]
          Length = 622

 Score = 1242 bits (3214), Expect = 0.0
 Identities = 622/622 (100%), Positives = 622/622 (100%)

Query: 1   METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 60
           METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
Sbjct: 1   METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 60

Query: 61  LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 120
           LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
Sbjct: 61  LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 120

Query: 121 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 180
           AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
Sbjct: 121 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 180

Query: 181 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 240
           YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
Sbjct: 181 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 240

Query: 241 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQ 300
           PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQ
Sbjct: 241 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQ 300

Query: 301 TKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAV 360
           TKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAV
Sbjct: 301 TKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAV 360

Query: 361 STRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVE 420
           STRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVE
Sbjct: 361 STRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVE 420

Query: 421 CLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFC 480
           CLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFC
Sbjct: 421 CLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFC 480

Query: 481 KRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSS 540
           KRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSS
Sbjct: 481 KRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSS 540

Query: 541 KSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQ 600
           KSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQ
Sbjct: 541 KSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQ 600

Query: 601 SFYMSSPGPSEYCPSERTISEI 622
           SFYMSSPGPSEYCPSERTISEI
Sbjct: 601 SFYMSSPGPSEYCPSERTISEI 622


>gi|191250773 spire homolog 1 isoform a [Homo sapiens]
          Length = 756

 Score = 1233 bits (3189), Expect = 0.0
 Identities = 622/636 (97%), Positives = 622/636 (97%), Gaps = 14/636 (2%)

Query: 1   METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 60
           METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
Sbjct: 121 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 180

Query: 61  LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 120
           LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
Sbjct: 181 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 240

Query: 121 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 180
           AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
Sbjct: 241 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 300

Query: 181 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 240
           YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
Sbjct: 301 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 360

Query: 241 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL--------------DVTTPESTKN 286
           PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL              DVTTPESTKN
Sbjct: 361 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN 420

Query: 287 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 346
           LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
Sbjct: 421 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 480

Query: 347 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 406
           VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
Sbjct: 481 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 540

Query: 407 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 466
           QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
Sbjct: 541 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 600

Query: 467 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 526
           RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
Sbjct: 601 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 660

Query: 527 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 586
           AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
Sbjct: 661 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 720

Query: 587 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 622
           VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
Sbjct: 721 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 756


>gi|55749600 spire homolog 2 [Homo sapiens]
          Length = 714

 Score =  454 bits (1168), Expect = e-127
 Identities = 273/639 (42%), Positives = 376/639 (58%), Gaps = 63/639 (9%)

Query: 2   ETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEGL 61
           E + ++SLG  IY+ALD+GL E+EERELSP LE+LID MAN    + S D G  AA+EG 
Sbjct: 94  EAQTVQSLGFAIYRALDWGLDESEERELSPQLERLIDLMAN----NDSEDSGCGAADEGY 149

Query: 62  GDEDEKRKIS----AIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTK 117
           G  +E+ +      ++R++   M+LCAA L     A  HYQAVCRALF ET+EL  FL +
Sbjct: 150 GGPEEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLAR 209

Query: 118 IKSAKENLKKIQEMEKSDESS-TDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNP 176
           ++ AKE L+K++E E   E+   +L+ L + DWAR WVQ+MR+LR GVKLKKVQE+++NP
Sbjct: 210 VREAKEMLQKLREDEPHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNP 269

Query: 177 LPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSA 236
           LP E+QLTP+EMLM DIR + Y LRKVMV+GDIPPR+KK AHE+ILDFIRSRPPL  VS 
Sbjct: 270 LPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSE 329

Query: 237 RKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRR---SRLDVTTPESTKNLVESSMV 293
           R+L+P PP+ RSLHE+ILEEIK ER+LRPV  E         L       + +   +S +
Sbjct: 330 RRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCI 389

Query: 294 NGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--------TLHKSTSSS 345
           N  +T    + G S  +  P   + LL+APTLAE++   + EE        TL +  S S
Sbjct: 390 NLSVT----DAGGSAQRPRP---RVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFS 442

Query: 346 SVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERR-------QPPQRRHSIEKETPTNV 398
               +     V   + +   PP       T  P  R       +P  R       + ++ 
Sbjct: 443 EHDLAQLRSEVASGLQSATHPP-----GGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDP 497

Query: 399 RQFLPPSRQSSRSLE-------------EFCYPVECLALTVEEVMHIRQVLVKAELEKYQ 445
              L  +R SS                 EF +PVE LALTVEEVM +R+VLVKAE+EK+ 
Sbjct: 498 SHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFL 557

Query: 446 QYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIF 505
           Q K+++++LKKGK+C CCR  +F  F+W  +C FCKR VC+ C  KM++PSK +  +P++
Sbjct: 558 QNKELFSSLKKGKICCCCRA-KFPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVY 616

Query: 506 SLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTM 565
           +LG  + QR          S A   P++    F S      +S EE  FP          
Sbjct: 617 TLGFESPQR---------VSAAKTAPIQRRDIFQSLQGPQWQSVEE-AFPHIYSHGCVLK 666

Query: 566 EVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYM 604
           +VC +C  F+++++ SSR+S+ + N   R  R+TQS Y+
Sbjct: 667 DVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYI 705


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 69/326 (21%), Positives = 120/326 (36%), Gaps = 58/326 (17%)

Query: 102 RALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLR 161
           R L A T EL      +KS K++L++ Q  E  D    D+   + A       Q+  +LR
Sbjct: 323 RQLQARTTELEA----LKSTKDSLER-QRSELEDRHQADIASYQEAIQ-----QLDAELR 372

Query: 162 NGVKLKKVQERQYNPL-----PIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKS 216
           N       Q R+Y  L      ++ ++  Y  L++   C+       +  G IP  L + 
Sbjct: 373 NTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECR-------IGFGPIPFSLPEG 425

Query: 217 AHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL 276
             +I            P  +  +K                +K+E K++ V   E     +
Sbjct: 426 LPKI------------PSVSTHIK----------------VKSEEKIKVVEKSEKETVIV 457

Query: 277 DVTTPES--TKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESE 334
           +  T E+  T+ + E            +E G    +    + +   ++P   E  S E E
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEET--KSPPAEEAASPEKE 515

Query: 335 EETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKET 394
            ++  K  + S      PE+   ++ +  K P K    + +P  E  + P    S EKE 
Sbjct: 516 AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK----AKSPAKEEAKSPPEAKSPEKEE 571

Query: 395 PTNVRQFLPPSRQSSRSLEEFCYPVE 420
             +  +   P +  S + EE   P E
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAE 597



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 37/179 (20%), Positives = 72/179 (40%), Gaps = 8/179 (4%)

Query: 253 ILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQV 312
           + EE K+  + +    EE + S  +V +PE  K+  +    +       ++    +  +V
Sbjct: 520 VKEEAKSPAEAKSPEKEEAK-SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578

Query: 313 PAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTR---KKPPKF 369
            +  K    A   A+  +     E         + SP+  + PV E   +    K P K 
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK- 637

Query: 370 LPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVECLALTVEE 428
              + +P  E  + P++  S EKE   +  +   P +  ++S E+   PV+  A + E+
Sbjct: 638 ---AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 42/191 (21%), Positives = 76/191 (39%), Gaps = 16/191 (8%)

Query: 238 KLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLV-ESSMVNGG 296
           K  P    P     +   E+K+  K +  + EE + S  +  +PE  K+ V E +     
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPAEAKSPEKAKSPVKEEAKSPAE 617

Query: 297 LTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSES-------EEETLHKSTSSSSVSP 349
             S  KE   S ++    ++ K   +PT  E  S E        E ++  K+ S      
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAK---SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674

Query: 350 SFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSS 409
             PE+      +  K P K    + +P  E  + P++  S  KE   +  +   P ++ +
Sbjct: 675 KSPEKAKSPVKAEAKSPEK----AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 730

Query: 410 RSLEEFCYPVE 420
           ++ E+   PV+
Sbjct: 731 KTPEKAKSPVK 741


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 45/190 (23%), Positives = 70/190 (36%), Gaps = 23/190 (12%)

Query: 245 RPRSLHERILEEIKAERKLRPVSPEEIRRSRLD------VTTPESTK----NLVESSMVN 294
           R  S  ER  +   ++R+ R  S  E+++SR+       +++P S      +L  S   +
Sbjct: 723 RSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGS 782

Query: 295 GGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEE 354
                Q  +     S+   +Q K   R P      SS    +   K+ S  S S S P  
Sbjct: 783 SPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP 842

Query: 355 PVLEAVSTRK-------------KPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQF 401
            V      R+              P +     S+P PE +     RHS    +P  V+  
Sbjct: 843 KVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS 902

Query: 402 LPPSRQSSRS 411
            PP +  SRS
Sbjct: 903 TPPRQSPSRS 912



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 49/191 (25%), Positives = 76/191 (39%), Gaps = 17/191 (8%)

Query: 226 RSRPPLNPVSARKLKPTP----PRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTP 281
           RSR P     +R   P       R R+   R     +  R+ R  S   +RR R    TP
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718

Query: 282 EST-KNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHK 340
           +   ++   S   N   TSQ +    ++S ++   R    R+ +L+   S      +L +
Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRS-NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777

Query: 341 STSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQ 400
           S S SS  P            ++  P +    SS P+ + R PP+R  S    +P   ++
Sbjct: 778 SLSGSSPCPK---------QKSQTPPRRSRSGSSQPKAKSRTPPRRSRS--SSSPPPKQK 826

Query: 401 FLPPSRQSSRS 411
              PSRQS  S
Sbjct: 827 SKTPSRQSHSS 837



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 33/163 (20%)

Query: 265  PVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPT 324
            P   E +R  R    TP   K    SS  +   +S +  +  S+S               
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS------------- 2630

Query: 325  LAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQP------ 378
                 SS S   +   S+SSSS SP+ P    L   ++ KKPP     S +P+       
Sbjct: 2631 ----SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLR 2686

Query: 379  ----------ERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRS 411
                      ERR+P  +    ++++ ++ R      R  SRS
Sbjct: 2687 DSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 48/210 (22%), Positives = 81/210 (38%), Gaps = 19/210 (9%)

Query: 210  PPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPE 269
            P R +  +   + D  R+ P     S    +P  P PR+L  R      +  K R  SPE
Sbjct: 1593 PRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRR--SRSGSSSKGRGPSPE 1650

Query: 270  EIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTL---A 326
                     +T  S ++  +S     G  S  +     T  + P +R+    +P L   A
Sbjct: 1651 G------SSSTESSPEHPPKSRTARRGSRSSPEPK---TKSRTPPRRRSSRSSPELTRKA 1701

Query: 327  ELD----SSESEEETLHKSTSSSSVSPSFPE-EPVLEAVSTRKKPPKFLPISSTPQPERR 381
             L     S+ S  ET  ++      SPS    EP  ++ S+R++     P + T     R
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761

Query: 382  QPPQRRHSIEKETPTNVRQFLPPSRQSSRS 411
             P  +   +++    + R+    +R+  RS
Sbjct: 1762 SPSPKPRGLQRSRSRSRREKTRTTRRRDRS 1791



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 36/178 (20%), Positives = 65/178 (36%), Gaps = 22/178 (12%)

Query: 256 EIKAERKLRPVSPEEIRRSRLDVTTPESTKNL------VESSMVNGGLTSQTKENGLST- 308
           + K E +LR +    ++R   D+   E  + +      +E  M   G   Q  +  ++T 
Sbjct: 35  DYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATF 94

Query: 309 -------------SQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSF--PE 353
                         ++ P QR  +     LAEL+  ++E        S S V  S   P+
Sbjct: 95  RLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQ 154

Query: 354 EPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRS 411
               EA     +PPK   +       R   P+++   +K+      +   P R+  +S
Sbjct: 155 RRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 57/235 (24%), Positives = 83/235 (35%), Gaps = 34/235 (14%)

Query: 211  PRLKKSAHEII--------LDFIRSR-PPLNPVSARKLKPTPPRPRS-LHERILEEIKAE 260
            PR+  SA+E +        LD  RSR PP  P  +R      P P S + +   + +   
Sbjct: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP 2442

Query: 261  RKLRPVSP-----EEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGL--------- 306
             + +P SP      +  R  +  TTP +    + S  V    +S    NG+         
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502

Query: 307  ---------STSQQVPAQRKKLLRAPTL-AELDSSESEEETLHKSTSSSSVSPSFPEEPV 356
                     ST  Q P+    L  A    +   SS S   +   S+SSSS S S      
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562

Query: 357  LEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRS 411
             E  S   +P   L    +P P  ++  +     E       R+    S  SS S
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS 2617



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 46/196 (23%), Positives = 69/196 (35%), Gaps = 20/196 (10%)

Query: 226  RSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTK 285
            RSR   +PVS R+ +   P       R        R      P   RRSR    TP  T+
Sbjct: 1910 RSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR--SRTPPVTR 1967

Query: 286  NLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSS 345
                S       +  T+    S +  V  +R +   +P       S +   T  +S S +
Sbjct: 1968 RRSRSR-----TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2022

Query: 346  SVS---PSFPEEPVLEAVSTRKKPPKFL---PISSTPQPER------RQPPQ-RRHSIEK 392
              +    S    P+L    +R + P  +     S TP+  R      R PP  RR S   
Sbjct: 2023 PPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASG 2082

Query: 393  ETPTNVRQFLPPSRQS 408
             +    R   PP+ ++
Sbjct: 2083 SSSDRSRSATPPATRN 2098



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 34/147 (23%), Positives = 58/147 (39%), Gaps = 13/147 (8%)

Query: 267  SPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLA 326
            SPE   +SRL   +P  +++     + +    +   ++G  +S +  A   + L  P  +
Sbjct: 1582 SPEVDSKSRL---SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL--PRRS 1636

Query: 327  ELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQR 386
               SS        + +SS+  SP  P +       +R  P         P+ + R PP+R
Sbjct: 1637 RSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE--------PKTKSRTPPRR 1688

Query: 387  RHSIEKETPTNVRQFLPPSRQSSRSLE 413
            R S      T   +    SR +S S E
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPE 1715


>gi|58082089 hypothetical protein LOC161394 [Homo sapiens]
          Length = 674

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 53/208 (25%), Positives = 74/208 (35%), Gaps = 22/208 (10%)

Query: 239 LKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNG--- 295
           L+P      ++ E +  E   E    PV P E        T  E    L+E     G   
Sbjct: 135 LEPPEEAKPNVTEDVFLESAMETDPDPVPPTETMSEVSGATVRERNLELLEEETEPGVPE 194

Query: 296 -GLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELD-------SSESEEETLHKSTSSSSV 347
             L  Q +E GL   +Q            +L E D         E+ EET  +ST     
Sbjct: 195 ESLRVQHEETGLEPPEQTKQDFPSEKLGESLEETDLQPPKMTKPETPEETQRESTEKKRT 254

Query: 348 SPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPP-----QRRHSIEK--ETPTNVRQ 400
            P  PE+  LE +   K+P K    +    PE  QP      QR+ + EK  E P   + 
Sbjct: 255 EP--PEQARLEFL--EKEPRKSSEEAGLEPPEETQPEVPEEMQRKATEEKGTELPERTKP 310

Query: 401 FLPPSRQSSRSLEEFCYPVECLALTVEE 428
             P  +    + E    P+E + L   E
Sbjct: 311 DFPDHKPRKSTDENVPEPLEEIKLEFPE 338


>gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog C
           [Homo sapiens]
          Length = 766

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 84/393 (21%), Positives = 151/393 (38%), Gaps = 49/393 (12%)

Query: 81  KLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTD 140
           K+  A L       ++Y+A  R       + +  + K   AK+ LK+ ++++K + +   
Sbjct: 220 KMHRAELQRARALQSYYEAKARKEKKIKSKKYHKVVKKGKAKKALKEFEQLQKVNPTVA- 278

Query: 141 LEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTL 200
           LEE++  + AR   ++    +N  K  K +      +  +Y L   + + + +   +   
Sbjct: 279 LEEMEKIENARMMERMSLKHQNSGKWAKSKA-----IMAKYDLEARQAMQEQLAKNKELT 333

Query: 201 RKVMVNGDIPPRLKKS-AHEIILDFIRSRPPLNP-----------VSARKLKPTPPRPRS 248
           +K+ V  +       +   E+++  + +   +N             S  K   T   P  
Sbjct: 334 QKLQVASESEEEEGGTEVEELLVPHVANEVQMNVDGPNPWMFRSCTSDTKEAATQEDPEQ 393

Query: 249 LHERILEEIKA-ERKLRPVSPEEI------------RRSRLDVTT-PESTKNLVESSMVN 294
           + E    E+ A E + RPV+ EEI            +RS L+    P S++   +SS   
Sbjct: 394 VPELAAHEVSASEAEERPVAEEEILLREFEERQSLRKRSELNQDAEPASSQETKDSSSQE 453

Query: 295 -----GGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSP 349
                  L+ + KE   S  Q+  ++       P +   + +  E E L    S    + 
Sbjct: 454 VLSELRALSQKLKEKHQSRKQKASSEGT----VPQVQREEPAPEEAEPLLLQRSERVQTL 509

Query: 350 SFPEEPVLEAVSTRKKPPKFLPISSTPQPER---RQPPQRRHSIEKETPTNVRQFLPPSR 406
              EE   E     K+ P+  P+    Q ER    +P   +   EKE   N++ FL    
Sbjct: 510 EELEELGKEDCFQNKELPR--PVLEGQQSERTPNNRPDAPKEKKEKEQLINLQNFLTTQS 567

Query: 407 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKA 439
            S RSL     P     L  EE    RQ++ +A
Sbjct: 568 PSVRSL---AVPTIIEELEDEEERDQRQMIKEA 597


>gi|61966703 NHS-like 2 [Homo sapiens]
          Length = 709

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 55/223 (24%), Positives = 91/223 (40%), Gaps = 43/223 (19%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPE------------EIRRSRLD 277
           P +  S++   PTP    SL    L    +  ++RPV PE            +  +SRL 
Sbjct: 345 PSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLS 404

Query: 278 VTTPESTKNLVESSMVNGGLTSQTKEN--------GLSTSQQ-------VPAQRKKLLRA 322
              P ++   ++ S ++  + S+TK +        G+  +Q+       +P   +  LR+
Sbjct: 405 FDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRS 464

Query: 323 PTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQ 382
             L  +  SE E++           SP + EEP  E V T  +     P++  P P  R+
Sbjct: 465 VRLRSVSKSEPEDDI---------ESPEYAEEPRAEEVFTLPERKTKPPVAEKP-PVARR 514

Query: 383 PPQRRHS----IEKETPTNVRQFLPP--SRQSSRSLEEFCYPV 419
           PP   H      E+   T+    +PP  S Q +R L +  Y V
Sbjct: 515 PPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTV 557


>gi|238624188 diffuse panbronchiolitis critical region 1 protein
           [Homo sapiens]
          Length = 1393

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 40/172 (23%), Positives = 64/172 (37%), Gaps = 10/172 (5%)

Query: 238 KLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGL 297
           K  P P  P    ER   E        P  P E    R  +   ++T +L E +  NG  
Sbjct: 732 KTTPFPAEPTENRERTANENTTPS---PAQPTE-NGDRTPLANEKTTPSLAEPTE-NGKR 786

Query: 298 TSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVL 357
           T    E   S+S + P +  +  R P   E  +S   E T ++  +++  +  FP EP  
Sbjct: 787 TPFANEKTTSSSAE-PTEHAE--RTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTE 843

Query: 358 EAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSS 409
              ST  +  K  P  + P   R        ++    PT   +  P + + +
Sbjct: 844 NRESTANE--KTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKT 893



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 36/169 (21%), Positives = 56/169 (33%), Gaps = 17/169 (10%)

Query: 233  PVSARKLKPTPPRPRSLHER--ILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVES 290
            P +  K  P+   P    ER  +  EI    +  P    E  R   +  TP   K     
Sbjct: 908  PFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGE--RIANEKATPSPAKPTEHG 965

Query: 291  SMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPS 350
                   T+ +        ++ P   +    +PT    +S+E  E T ++ T+ S     
Sbjct: 966  ETTVNEDTTPSSAEPTENGERTPLANENTTTSPT----ESTEHGERTANEKTTPS----- 1016

Query: 351  FPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVR 399
             P EP      T     K +P  + P       P      E  TP+ V+
Sbjct: 1017 -PAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSAN---ENTTPSPVK 1061



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 41/184 (22%), Positives = 66/184 (35%), Gaps = 26/184 (14%)

Query: 209  IPPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHER---------ILEEIKA 259
            IP   K + HE           + P +     P+P +P    E+         +  E   
Sbjct: 1035 IPSPAKPTEHE----------EMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPT 1084

Query: 260  ERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQV----PAQ 315
            E   +  S  E     L   T    +    +  +       T+    +TS  V    PA+
Sbjct: 1085 EHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVITPAPAE 1144

Query: 316  RKKLLRAPTLA-ELDSSESEEETLH--KSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPI 372
              K  +  TLA E  +  +E+ T H  K+TS++  +   PE+P L +  T     K  P+
Sbjct: 1145 PIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPV 1204

Query: 373  SSTP 376
               P
Sbjct: 1205 PEKP 1208


>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
          Length = 1035

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 55/206 (26%), Positives = 80/206 (38%), Gaps = 25/206 (12%)

Query: 225 IRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPEST 284
           +RS PP   VS   L+P  P+ R  H R          LRP  P + R S L +  PE+ 
Sbjct: 414 LRSEPPKIGVSHLCLEP--PKTRGSHLRPEPPETGVSHLRP-EPPKTRVSSLHLEPPETG 470

Query: 285 KNLV-----ESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--- 336
            + +     E  + +  L  +  + G+S     P + +     P  +E   S    E   
Sbjct: 471 VSHLCPEPPEKDVSH--LRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPK 528

Query: 337 ----TLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERR-------QPPQ 385
               +LH++   SSVS   PE P       R +PPK    S  P+P          +PP+
Sbjct: 529 ILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPK 588

Query: 386 RR-HSIEKETPTNVRQFLPPSRQSSR 410
            R  S+  E P      L P    +R
Sbjct: 589 TRVSSLPPEPPETGVSHLCPEPPETR 614



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 53/205 (25%), Positives = 69/205 (33%), Gaps = 22/205 (10%)

Query: 225 IRSRPPLNP-VSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPE--------EIRRSR 275
           + S PP  P      L P PP  R  H R          LRP  P+        E   + 
Sbjct: 591 VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTG 650

Query: 276 LDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEE 335
           +    PE  K  V S      L  +  E G+S     P + +     P   E   S    
Sbjct: 651 VSHLCPEPPKTRVSS------LPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHP 704

Query: 336 E-------TLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRH 388
           E       +LH     S VS   PE P       R +PPK    S  P+P   +    R 
Sbjct: 705 EPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRP 764

Query: 389 SIEKETPTNVRQFLPPSRQSSRSLE 413
              +   +++   LP  R SS  LE
Sbjct: 765 EPPETGVSHLHPELPKPRVSSLHLE 789



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 56/204 (27%), Positives = 79/204 (38%), Gaps = 31/204 (15%)

Query: 229 PPLNPVSARKLKPTPPRPRSLH-----------ERILEEIKAE-RKLRPVSPEEIRRSRL 276
           PP   VS   L P PP+ R  H           +  LE  K+    LRP  P E   S L
Sbjct: 274 PPGTGVS--HLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRP-EPSETGVSHL 330

Query: 277 DVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRK--KLLRAPTLAEL-----D 329
               PE  K LV S      L  +  E G+S     P + +   L + P  A +     +
Sbjct: 331 H---PEPPKTLVSS------LHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPE 381

Query: 330 SSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHS 389
             ++    L   T  + VSP FPE P     + R +PPK        +P + +    R  
Sbjct: 382 PPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPE 441

Query: 390 IEKETPTNVRQFLPPSRQSSRSLE 413
             +   +++R   P +R SS  LE
Sbjct: 442 PPETGVSHLRPEPPKTRVSSLHLE 465



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 48/193 (24%), Positives = 69/193 (35%), Gaps = 23/193 (11%)

Query: 225 IRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPEST 284
           +R  PP   VS   L P PP+ R  H R          LRP  P +I  S L    PES+
Sbjct: 486 LRPEPPDTGVS--HLCPEPPKTRVSHLRPEPSETGVSHLRP-EPPKILVSSLHQAPPESS 542

Query: 285 KNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSS-------ESEEET 337
            +          L  +  E G+S  +  P + +     P   +   S       ++   +
Sbjct: 543 VS---------HLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSS 593

Query: 338 LHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTN 397
           L      + VS   PE P       R +PP+       P+P    P  R +S+  E P  
Sbjct: 594 LPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP----PKTRMYSLRPEPPNT 649

Query: 398 VRQFLPPSRQSSR 410
               L P    +R
Sbjct: 650 GVSHLCPEPPKTR 662



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 22/163 (13%)

Query: 225 IRSRPPLNP-VSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPES 283
           + S PP  P      L P PP  R  H R         +L P  P + R S L    PES
Sbjct: 663 VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHP-EPPKTRVSSLHAEPPES 721

Query: 284 TKNLVESSMVNGGLTSQTKENGLSTSQ-QVPAQRKKLLRAPTLAELDSSESEEETLHKST 342
             +          L  +  E G+S  + + P  R   LR   L      E+    L    
Sbjct: 722 RVS---------HLCPEPPETGVSHLRPEPPKPRVSSLRPEPL------ETRVSHLRPEP 766

Query: 343 SSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQ 385
             + VS   PE P     S   +PPK   +SS     R +PP+
Sbjct: 767 PETGVSHLHPELPKPRVSSLHLEPPKTRRVSSL----RLEPPK 805


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 40/166 (24%), Positives = 61/166 (36%), Gaps = 10/166 (6%)

Query: 238 KLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGL 297
           K  P P  P    ER   E        P  P E    R  +   ++T +L E +  NG  
Sbjct: 794 KTTPFPAEPTENRERTANENTTPS---PAQPTE-NGDRTPLANEKTTPSLAEPTE-NGKR 848

Query: 298 TSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVL 357
           T    E   S+S + P +  +  R P   E  +S   E T ++  +++  +  FP EP  
Sbjct: 849 TPFANEKTTSSSAE-PTEHAE--RTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTE 905

Query: 358 EAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLP 403
              ST  +  K  P  + P   R        ++    PT   +  P
Sbjct: 906 NRESTANE--KTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTP 949


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/191 (20%), Positives = 71/191 (37%), Gaps = 11/191 (5%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVE 289
           P  P S    +PTP   +S      E      K  P +P+E   +      P + K    
Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280

Query: 290 SSMVNGGLTS-----QTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSS 344
           ++      T+      T +    T+ + PA       APT  +  +  + +E    +   
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340

Query: 345 SSVSPS--FPEEPVLEAVSTRKKP----PKFLPISSTPQPERRQPPQRRHSIEKETPTNV 398
           +  +P    P  P   A +T K+P    PK    ++T +P    P +   +  K  PT  
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400

Query: 399 RQFLPPSRQSS 409
           ++  P + +S+
Sbjct: 401 KEPAPTTTKSA 411



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 16/175 (9%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTT---PESTKN 286
           P  P      +P P  P+      L+E        P +P++     L  TT   P ST +
Sbjct: 628 PKEPAPTTPKEPAPTTPKGTAPTTLKEPA------PTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 287 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--TLHKSTSS 344
              +          T +    T+ + PA        PT +E+ +  + +E  T+HKS   
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 741

Query: 345 SSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVR 399
           S+  P    EP  +A+    K P    + +T  P   +P     + +K T  ++R
Sbjct: 742 ST--PELSAEPTPKALENSPKEP---GVPTTKTPAATKPEMTTTAKDKTTERDLR 791



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 10/173 (5%)

Query: 233 PVSARKLKPTPPR---PRSLHERILEEIK--AERKLRPVSPEEIRRSRLDVTTPESTKNL 287
           P + ++  PT P+   P +L E      K  A ++L P + +E   +  D   P + K  
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623

Query: 288 VESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSV 347
             ++      T+  +    +     P   K+   APT  +  + +    T  K  +S++ 
Sbjct: 624 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 348 SPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQ 400
               P  P   A +T K+P    P    P      PP    + E  TPT  ++
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT---TSEVSTPTTTKE 731



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 50/220 (22%), Positives = 77/220 (35%), Gaps = 25/220 (11%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIK---------AERKLRPVSPEEIRRSRLDVTT 280
           P  P      +PTP  P+       E            A +K  P +P+E   +      
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373

Query: 281 PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHK 340
           P +TK    ++      T+ TK    +T +  P   K     P      +++    T  K
Sbjct: 374 PTTTKEPSPTTPKEPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432

Query: 341 S---TSSSSVSPSFPEEPVLE-----AVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEK 392
               T+    +P+ P+EP        A +T KKP    P    P   +   P    + +K
Sbjct: 433 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT---TPKK 489

Query: 393 ETPTNVRQFLP--PSRQSSRSLEEFC--YPVECLALTVEE 428
            TPT   +  P  P + +  + EE     P E    T EE
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/191 (20%), Positives = 71/191 (37%), Gaps = 11/191 (5%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVE 289
           P  P S    +PTP   +S      E      K  P +P+E   +      P + K    
Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321

Query: 290 SSMVNGGLTS-----QTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSS 344
           ++      T+      T +    T+ + PA       APT  +  +  + +E    +   
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381

Query: 345 SSVSPS--FPEEPVLEAVSTRKKP----PKFLPISSTPQPERRQPPQRRHSIEKETPTNV 398
           +  +P    P  P   A +T K+P    PK    ++T +P    P +   +  K  PT  
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441

Query: 399 RQFLPPSRQSS 409
           ++  P + +S+
Sbjct: 442 KEPAPTTTKSA 452



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 16/175 (9%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTT---PESTKN 286
           P  P      +P P  P+      L+E        P +P++     L  TT   P ST +
Sbjct: 669 PKEPAPTTPKEPAPTTPKGTAPTTLKEPA------PTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 287 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--TLHKSTSS 344
              +          T +    T+ + PA        PT +E+ +  + +E  T+HKS   
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 782

Query: 345 SSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVR 399
           S+  P    EP  +A+    K P    + +T  P   +P     + +K T  ++R
Sbjct: 783 ST--PELSAEPTPKALENSPKEP---GVPTTKTPAATKPEMTTTAKDKTTERDLR 832



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 10/173 (5%)

Query: 233 PVSARKLKPTPPR---PRSLHERILEEIK--AERKLRPVSPEEIRRSRLDVTTPESTKNL 287
           P + ++  PT P+   P +L E      K  A ++L P + +E   +  D   P + K  
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664

Query: 288 VESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSV 347
             ++      T+  +    +     P   K+   APT  +  + +    T  K  +S++ 
Sbjct: 665 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 348 SPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQ 400
               P  P   A +T K+P    P    P      PP    + E  TPT  ++
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT---TSEVSTPTTTKE 772



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 50/220 (22%), Positives = 77/220 (35%), Gaps = 25/220 (11%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIK---------AERKLRPVSPEEIRRSRLDVTT 280
           P  P      +PTP  P+       E            A +K  P +P+E   +      
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414

Query: 281 PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHK 340
           P +TK    ++      T+ TK    +T +  P   K     P      +++    T  K
Sbjct: 415 PTTTKEPSPTTPKEPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473

Query: 341 S---TSSSSVSPSFPEEPVLE-----AVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEK 392
               T+    +P+ P+EP        A +T KKP    P    P   +   P    + +K
Sbjct: 474 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT---TPKK 530

Query: 393 ETPTNVRQFLP--PSRQSSRSLEEFC--YPVECLALTVEE 428
            TPT   +  P  P + +  + EE     P E    T EE
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/191 (20%), Positives = 71/191 (37%), Gaps = 11/191 (5%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVE 289
           P  P S    +PTP   +S      E      K  P +P+E   +      P + K    
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373

Query: 290 SSMVNGGLTS-----QTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSS 344
           ++      T+      T +    T+ + PA       APT  +  +  + +E    +   
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433

Query: 345 SSVSPS--FPEEPVLEAVSTRKKP----PKFLPISSTPQPERRQPPQRRHSIEKETPTNV 398
           +  +P    P  P   A +T K+P    PK    ++T +P    P +   +  K  PT  
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493

Query: 399 RQFLPPSRQSS 409
           ++  P + +S+
Sbjct: 494 KEPAPTTTKSA 504



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 16/175 (9%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTT---PESTKN 286
           P  P      +P P  P+      L+E        P +P++     L  TT   P ST +
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPA------PTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 287 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--TLHKSTSS 344
              +          T +    T+ + PA        PT +E+ +  + +E  T+HKS   
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 834

Query: 345 SSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVR 399
           S+  P    EP  +A+    K P    + +T  P   +P     + +K T  ++R
Sbjct: 835 ST--PELSAEPTPKALENSPKEP---GVPTTKTPAATKPEMTTTAKDKTTERDLR 884



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 10/173 (5%)

Query: 233 PVSARKLKPTPPR---PRSLHERILEEIK--AERKLRPVSPEEIRRSRLDVTTPESTKNL 287
           P + ++  PT P+   P +L E      K  A ++L P + +E   +  D   P + K  
Sbjct: 657 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716

Query: 288 VESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSV 347
             ++      T+  +    +     P   K+   APT  +  + +    T  K  +S++ 
Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 348 SPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQ 400
               P  P   A +T K+P    P    P      PP    + E  TPT  ++
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT---TSEVSTPTTTKE 824



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 50/220 (22%), Positives = 77/220 (35%), Gaps = 25/220 (11%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIK---------AERKLRPVSPEEIRRSRLDVTT 280
           P  P      +PTP  P+       E            A +K  P +P+E   +      
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466

Query: 281 PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHK 340
           P +TK    ++      T+ TK    +T +  P   K     P      +++    T  K
Sbjct: 467 PTTTKEPSPTTPKEPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525

Query: 341 S---TSSSSVSPSFPEEPVLE-----AVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEK 392
               T+    +P+ P+EP        A +T KKP    P    P   +   P    + +K
Sbjct: 526 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT---TPKK 582

Query: 393 ETPTNVRQFLP--PSRQSSRSLEEFC--YPVECLALTVEE 428
            TPT   +  P  P + +  + EE     P E    T EE
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/191 (20%), Positives = 71/191 (37%), Gaps = 11/191 (5%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVE 289
           P  P S    +PTP   +S      E      K  P +P+E   +      P + K    
Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 414

Query: 290 SSMVNGGLTS-----QTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSS 344
           ++      T+      T +    T+ + PA       APT  +  +  + +E    +   
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474

Query: 345 SSVSPS--FPEEPVLEAVSTRKKP----PKFLPISSTPQPERRQPPQRRHSIEKETPTNV 398
           +  +P    P  P   A +T K+P    PK    ++T +P    P +   +  K  PT  
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534

Query: 399 RQFLPPSRQSS 409
           ++  P + +S+
Sbjct: 535 KEPAPTTTKSA 545



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 16/175 (9%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTT---PESTKN 286
           P  P      +P P  P+      L+E        P +P++     L  TT   P ST +
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPA------PTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 287 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--TLHKSTSS 344
              +          T +    T+ + PA        PT +E+ +  + +E  T+HKS   
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 875

Query: 345 SSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVR 399
           S+  P    EP  +A+    K P    + +T  P   +P     + +K T  ++R
Sbjct: 876 ST--PELSAEPTPKALENSPKEP---GVPTTKTPAATKPEMTTTAKDKTTERDLR 925



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 10/173 (5%)

Query: 233 PVSARKLKPTPPR---PRSLHERILEEIK--AERKLRPVSPEEIRRSRLDVTTPESTKNL 287
           P + ++  PT P+   P +L E      K  A ++L P + +E   +  D   P + K  
Sbjct: 698 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757

Query: 288 VESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSV 347
             ++      T+  +    +     P   K+   APT  +  + +    T  K  +S++ 
Sbjct: 758 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 348 SPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQ 400
               P  P   A +T K+P    P    P      PP    + E  TPT  ++
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT---TSEVSTPTTTKE 865



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 50/220 (22%), Positives = 77/220 (35%), Gaps = 25/220 (11%)

Query: 230 PLNPVSARKLKPTPPRPRSLHERILEEIK---------AERKLRPVSPEEIRRSRLDVTT 280
           P  P      +PTP  P+       E            A +K  P +P+E   +      
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507

Query: 281 PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHK 340
           P +TK    ++      T+ TK    +T +  P   K     P      +++    T  K
Sbjct: 508 PTTTKEPSPTTPKEPAPTT-TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566

Query: 341 S---TSSSSVSPSFPEEPVLE-----AVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEK 392
               T+    +P+ P+EP        A +T KKP    P    P   +   P    + +K
Sbjct: 567 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT---TPKK 623

Query: 393 ETPTNVRQFLP--PSRQSSRSLEEFC--YPVECLALTVEE 428
            TPT   +  P  P + +  + EE     P E    T EE
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663


>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 6 [Homo sapiens]
          Length = 1093

 Score = 37.7 bits (86), Expect = 0.032
 Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 18/147 (12%)

Query: 255 EEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGL------ST 308
           E +K + K RP SP  I    + V T +   +   SS  +   T +T E+        S+
Sbjct: 246 ERLKQKHKKRPESPPSILTPPV-VPTADKVSSSASSSSHHEASTQETSESSRESKGKKSS 304

Query: 309 SQQVPAQRKKLLRAPTLAELDSSESEEETLHKST--------SSSSVSPSFPEEPVLEAV 360
           S  +  + KKL     ++   S+ S   +   S+        SS   SP F   P LE  
Sbjct: 305 SHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQP 364

Query: 361 STRK--KPPKFLPISSTPQPERRQPPQ 385
              K  KP    P S+ P P   +PP+
Sbjct: 365 EEDKYSKPTAPAP-SAPPSPSAPEPPK 390


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 37.0 bits (84), Expect = 0.054
 Identities = 40/191 (20%), Positives = 79/191 (41%), Gaps = 30/191 (15%)

Query: 240  KPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTS 299
            K  PP P+ + + ++E+I  E+  R +  E+++ +++    PE +K +V        +  
Sbjct: 9172 KKAPPPPKVIKKPVIEKI--EKTSRRMEEEKVQVTKV----PEVSKKIVPQKPSRTPVQE 9225

Query: 300  QT---KENGLSTSQQVPAQRKKLLRAPTLAELDSSESE-------EETLH----KSTSSS 345
            +    K   + T + V ++ K    + T  E+  +  E       EE +H    K     
Sbjct: 9226 EVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPP 9285

Query: 346  SVSPSFPEEPVLEAVSTRKKP-------PKFLPISSTPQPERRQP---PQRRHSIEKETP 395
               P  PE+P  E V+    P       PK   +   P PE ++P   P++  +   + P
Sbjct: 9286 PKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP 9345

Query: 396  TNVRQFLPPSR 406
               ++ +P  +
Sbjct: 9346 EVPKKPVPEEK 9356



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 42/206 (20%), Positives = 79/206 (38%), Gaps = 40/206 (19%)

Query: 233  PVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSM 292
            PV     +P P +P++   ++L++   E K+    P++++     V  PE  K + E   
Sbjct: 9794 PVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKV--PEEPKKVFEEK- 9850

Query: 293  VNGGLTSQTKENGLSTSQQVPAQRKKL----------------LRAPTL-AELDSS---- 331
            +   +T + KE     + +VP + K++                +R P +  EL+      
Sbjct: 9851 IRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAF 9910

Query: 332  -------------ESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQP 378
                         E EEE +H+     +     P  PV      RK  P+       P P
Sbjct: 9911 EEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE--EKKPVPVP 9968

Query: 379  ERRQ-PPQRRHSIEKETPTNVRQFLP 403
            ++++ PP +   + K+    V   +P
Sbjct: 9969 KKKEAPPAKVPEVPKKPEEKVPVLIP 9994


>gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]
          Length = 1049

 Score = 37.0 bits (84), Expect = 0.054
 Identities = 53/227 (23%), Positives = 94/227 (41%), Gaps = 23/227 (10%)

Query: 193 IRCKRYTLRKVMVNGDIPPRLKKSA--HEIILDFIRSRPPLNPVSARKLKPTPPRPRSLH 250
           +R ++   R+ +V+  I P LK  A  HE I    R+R         K++  P R   + 
Sbjct: 55  LRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERART--ENFLKHKIRSRPDRSELVR 112

Query: 251 ERILEEIKAERKLRPVSPEEIRRSRL------DVTTPESTKNLVESSMVNGGLTSQTKEN 304
             ILEE  AE  L+  +  +++R+RL       +        LVE +++   + S  KE 
Sbjct: 113 MHILEETFAEPSLQ-ATQMKLKRARLADDLNEKIAQRPGPMELVEKNILP--VDSSVKEA 169

Query: 305 GLSTSQQVPAQRKKLLRAPTLAELDSSE--SEEETLHKSTSSSSVSPSFPEEPVLEAVST 362
            +   ++     +         + DSS+  S ++   + +  S+ SPS P+     +  T
Sbjct: 170 IIGVGKEDYPHTQ----GDFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSESPSPVT 225

Query: 363 RKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSS 409
              P +F  +S T     + PP    + ++  P      LP +  SS
Sbjct: 226 TNTPAQFASVSPTVPEFLKTPP----TADQPPPRPAAPVLPTNTVSS 268



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 42/184 (22%), Positives = 71/184 (38%), Gaps = 25/184 (13%)

Query: 233 PVSARKLKPTP-----PRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNL 287
           P + R+   TP     P P SL +  + E+K E KLR +     +   ++   P    N 
Sbjct: 379 PNTPRQNTSTPVRKPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVN- 437

Query: 288 VESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSV 347
             S +  GG+ +      +S+S  V +  +  +  P             TLH +T +SSV
Sbjct: 438 -SSGLAAGGIVA------VSSSAIVTSNPEVTVALPV-----------TTLH-NTVTSSV 478

Query: 348 SPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQ 407
           S    E P     +  +      P+  +P P  +       +   +T T +   + PS+ 
Sbjct: 479 STLKAELPPTGTSNATRVENVHSPLPISPSPSEQSSLSTDDTNMADTFTEIMTMMSPSQF 538

Query: 408 SSRS 411
            S S
Sbjct: 539 LSSS 542


>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
          Length = 2245

 Score = 36.6 bits (83), Expect = 0.071
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 271 IRRSRLDVTTPESTKNLVESSMVNGGLTS------QTKENGLSTSQQVPAQRKKLLRAPT 324
           +++   +V   + T NLV    ++G   S      QT    L+T+Q VP      + A +
Sbjct: 176 LQKQTANVVPVQRTCNLVTPVSISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQS 235

Query: 325 LAELDSSESEEETLHKSTSSSSVSPSFPEEP 355
           + EL +SESE   L  +TS S ++ S   EP
Sbjct: 236 ILELPTSESESNVL-GATSGSLIAVSIESEP 265


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 36.6 bits (83), Expect = 0.071
 Identities = 45/178 (25%), Positives = 59/178 (33%), Gaps = 8/178 (4%)

Query: 227 SRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERK------LRPVSPEEIRRSRLDVTT 280
           S P L P S   L P P   RS    +               L P +   +  S     T
Sbjct: 70  STPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLT 129

Query: 281 PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRA--PTLAELDSSESEEETL 338
           P ST  L  SS      +S+      ST    P+ R  L R+  PTL    +      + 
Sbjct: 130 PSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSST 189

Query: 339 HKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPT 396
              T SS+ + +    P+L   ST    P   PI +        P  R       TPT
Sbjct: 190 PTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPT 247



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 48/200 (24%), Positives = 65/200 (32%), Gaps = 16/200 (8%)

Query: 229 PPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLV 288
           P L P S   L P+     +   + +    +   L P SP  +  S     TP +T  L 
Sbjct: 8   PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67

Query: 289 ESSMVN------GGLTSQTKENGLSTSQQVPAQRKKLL--RAPTLAELDS---SESEEET 337
            SS           LT Q      ST    P+    L     PTL   ++   + S   T
Sbjct: 68  PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT 127

Query: 338 LHKSTSSSSVSPSFP-----EEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEK 392
           L  S++ +    S P       P+L   ST    P   PI +        P         
Sbjct: 128 LTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPS 187

Query: 393 ETPTNVRQFLPPSRQSSRSL 412
            TPT      P    SSR +
Sbjct: 188 STPTLTPSSTPTLTPSSRPI 207


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 36.6 bits (83), Expect = 0.071
 Identities = 45/178 (25%), Positives = 59/178 (33%), Gaps = 8/178 (4%)

Query: 227 SRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERK------LRPVSPEEIRRSRLDVTT 280
           S P L P S   L P P   RS    +               L P +   +  S     T
Sbjct: 70  STPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLT 129

Query: 281 PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRA--PTLAELDSSESEEETL 338
           P ST  L  SS      +S+      ST    P+ R  L R+  PTL    +      + 
Sbjct: 130 PSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSST 189

Query: 339 HKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPT 396
              T SS+ + +    P+L   ST    P   PI +        P  R       TPT
Sbjct: 190 PTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPT 247



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 48/200 (24%), Positives = 65/200 (32%), Gaps = 16/200 (8%)

Query: 229 PPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLV 288
           P L P S   L P+     +   + +    +   L P SP  +  S     TP +T  L 
Sbjct: 8   PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67

Query: 289 ESSMVN------GGLTSQTKENGLSTSQQVPAQRKKLL--RAPTLAELDS---SESEEET 337
            SS           LT Q      ST    P+    L     PTL   ++   + S   T
Sbjct: 68  PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT 127

Query: 338 LHKSTSSSSVSPSFP-----EEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEK 392
           L  S++ +    S P       P+L   ST    P   PI +        P         
Sbjct: 128 LTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPS 187

Query: 393 ETPTNVRQFLPPSRQSSRSL 412
            TPT      P    SSR +
Sbjct: 188 STPTLTPSSTPTLTPSSRPI 207


>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
          Length = 842

 Score = 36.6 bits (83), Expect = 0.071
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 14/170 (8%)

Query: 244 PRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKE 303
           P PR   E+ + + K ++ ++PV P  +R +R      +     V S+     +T    E
Sbjct: 177 PGPRQTSEKKVSD-KEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANE 235

Query: 304 NGLSTSQQVPAQRKKLLRAPTLAELDSS---ESEEETLHKSTSSSS-VSPS--FPEEPVL 357
           N      +VP++ +      T  +   S   +SEE TL+  T+++S ++P     +   L
Sbjct: 236 N--EPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENL 293

Query: 358 EAVSTRKKPPKFLPISSTPQPERRQPPQ--RRHSIEKETPTNVRQFLPPS 405
             ++T K   K    S  P+    QP    + + +   TP +   FL PS
Sbjct: 294 PEINTAKIKGK---NSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPS 340


>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
          Length = 846

 Score = 36.6 bits (83), Expect = 0.071
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 14/170 (8%)

Query: 244 PRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKE 303
           P PR   E+ + + K ++ ++PV P  +R +R      +     V S+     +T    E
Sbjct: 177 PGPRQTSEKKVSD-KEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANE 235

Query: 304 NGLSTSQQVPAQRKKLLRAPTLAELDSS---ESEEETLHKSTSSSS-VSPS--FPEEPVL 357
           N      +VP++ +      T  +   S   +SEE TL+  T+++S ++P     +   L
Sbjct: 236 N--EPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENL 293

Query: 358 EAVSTRKKPPKFLPISSTPQPERRQPPQ--RRHSIEKETPTNVRQFLPPS 405
             ++T K   K    S  P+    QP    + + +   TP +   FL PS
Sbjct: 294 PEINTAKIKGK---NSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPS 340


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 36.2 bits (82), Expect = 0.093
 Identities = 45/192 (23%), Positives = 68/192 (35%), Gaps = 29/192 (15%)

Query: 215  KSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRS 274
            K +H+  L F ++ P       R++  TP  P    ER+    K+  K+ P      + S
Sbjct: 1107 KKSHQKSLSFSKTTP-------RRISHTPQTPLYTPERLQ---KSPAKMTPTKQAAFKES 1156

Query: 275  RLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESE 334
              D ++P     L +S +      +Q  E G S   + P   K+    P           
Sbjct: 1157 LKDSSSPGHDSPL-DSKITPQKRHTQAGE-GTSLETKTPRTPKRQGTQPP------GFLP 1208

Query: 335  EETLHKSTSSSSVSPSFPEEPVLEAVSTRKK-----------PPKFLPISSTPQPERRQP 383
              T   S +SS  SPS P  P       R++           PP+      TPQ +  Q 
Sbjct: 1209 NCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQ 1268

Query: 384  PQRRHSIEKETP 395
            P    +   E P
Sbjct: 1269 PHVLRAARAEEP 1280


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 36.2 bits (82), Expect = 0.093
 Identities = 39/177 (22%), Positives = 63/177 (35%), Gaps = 4/177 (2%)

Query: 235 SARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVN 294
           S R+ K   P PR     +  E K        SP    +SR     PE  +   E    +
Sbjct: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSR---SPRHRTKSRSPSPAPEKKEKTPELPEPS 227

Query: 295 GGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEE 354
             +   + +   STS  +   + + +  P     + +  +E+   K+   S         
Sbjct: 228 VKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSR 287

Query: 355 PVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRS 411
               + S  +   +    S +  P RR  P+RR S  + TP   R   PP  + SRS
Sbjct: 288 TRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPR-RMPPPPRHRRSRS 343



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 44/185 (23%), Positives = 66/185 (35%), Gaps = 16/185 (8%)

Query: 237 RKLKPTP-PRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSM--- 292
           ++  P+P P+PR +     EE K  +     S ++ R+ R       S      SS    
Sbjct: 447 KRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER 506

Query: 293 -----VNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSV 347
                V  G   + + +  S S   P+ RK+            S S   T  + + S + 
Sbjct: 507 PKRSHVKNGEVGRRRRHSPSRSAS-PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAP 565

Query: 348 SPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPP-QRRHSIEKETPTNVRQFLPPSR 406
            P     P       R++ P   P   +P P R  PP QRR+S     P   R   PP  
Sbjct: 566 PPRRRRTPT---PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS--PSPPPKRRTASPPPP 620

Query: 407 QSSRS 411
              R+
Sbjct: 621 PKRRA 625



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 49/204 (24%), Positives = 71/204 (34%), Gaps = 52/204 (25%)

Query: 233 PVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSM 292
           P   R+L P+   PR  H          R   P +P    ++R   T  +S +       
Sbjct: 382 PRKTRRLSPSASPPRRRH----------RPSPPATPPP--KTRHSPTPQQSNRTRKSRVS 429

Query: 293 VNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEE----------------- 335
           V+ G TS     G  T  +   +R+    AP   +++ SESEE                 
Sbjct: 430 VSPGRTS-----GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQ 484

Query: 336 ---ETLHKSTSSSSVSPSFPEEPVLEAVST-------RKKPPKFLPISSTPQPERRQ--- 382
              +    S+ S S S S  E P    V         R  P +    S++P P +RQ   
Sbjct: 485 YRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSR----SASPSPRKRQKET 540

Query: 383 -PPQRRHSIEKETPTNVRQFLPPS 405
            P  RR       PT  R+   P+
Sbjct: 541 SPRGRRRRSPSPPPTRRRRSPSPA 564



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 38/187 (20%), Positives = 68/187 (36%), Gaps = 18/187 (9%)

Query: 229 PPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLV 288
           PP  P   R+  P+PP  R +      + ++    +  SP    + R   +   ST+   
Sbjct: 617 PP--PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTRE-A 673

Query: 289 ESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESE-----EETLHKSTS 343
            S   N   +   +     TS   P  R+    +P   +  S  +        T      
Sbjct: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI 733

Query: 344 SSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETP-TNVRQFL 402
             + SPS   + V    S+R        +S +P+P  ++PP     ++ ++P TN    +
Sbjct: 734 KKAASPS--PQSVRRVSSSRS-------VSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV 784

Query: 403 PPSRQSS 409
           P  +  S
Sbjct: 785 PVKKAKS 791


>gi|38373677 guanine nucleotide-releasing factor 2 isoform b [Homo
           sapiens]
          Length = 1095

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 326 AELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQ 385
           AEL  ++ E E L+K+T  S  +   P+    E    +   P    + ++P P    PP+
Sbjct: 250 AELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPP--ALPPK 307

Query: 386 RRHSIEKETPTNVRQFLPPSRQSSRS 411
           +R S    +PT V    P SR +S S
Sbjct: 308 KRQS--APSPTRVAVVAPMSRATSGS 331


>gi|38373675 guanine nucleotide-releasing factor 2 isoform a [Homo
           sapiens]
          Length = 1077

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 326 AELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQ 385
           AEL  ++ E E L+K+T  S  +   P+    E    +   P    + ++P P    PP+
Sbjct: 232 AELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPP--ALPPK 289

Query: 386 RRHSIEKETPTNVRQFLPPSRQSSRS 411
           +R S    +PT V    P SR +S S
Sbjct: 290 KRQS--APSPTRVAVVAPMSRATSGS 313


>gi|68508961 centromere protein C 1 [Homo sapiens]
          Length = 943

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 46/185 (24%), Positives = 74/185 (40%), Gaps = 23/185 (12%)

Query: 245 RPRSLHERILEEIKAERKLRPVSPEEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKEN 304
           + R  H  IL +  A  K     P  +  S+    T   T   +    VN      TK  
Sbjct: 345 KSREKHHNILPKTLANDK-HSHKPHPVETSQPSDKTVLDTSYALIGETVNN--YRSTKYE 401

Query: 305 GLSTSQQVPA---------QRKKLLRAPTLAELDSSESEEETLHKS-------TSSSSVS 348
             S + + P+         QR+K +  P   +LD  +S++E +H S         +S  +
Sbjct: 402 MYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRN 461

Query: 349 PSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIE---KETPTNVRQFLPPS 405
               EE   + VS ++ PP     SST + ++ +  ++R S E   K  P  V   +  S
Sbjct: 462 MEEHEEMGNDCVSKKQMPPVGSKKSST-RKDKEESKKKRFSSESKNKLVPEEVTSTVTKS 520

Query: 406 RQSSR 410
           R+ SR
Sbjct: 521 RRISR 525


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 44/191 (23%), Positives = 76/191 (39%), Gaps = 25/191 (13%)

Query: 210 PPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRS-LHERILEEIKAERKLRPVSP 268
           PP L+K+A  +  +  ++ PP++P   +   P  P  RS      L +      L  +SP
Sbjct: 394 PPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSP 453

Query: 269 EEIRRSRLDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQ--VPAQRKKLLRAPTLA 326
           ++ + S   +  PES K+        GG     K +     Q+   P  RK     P+ +
Sbjct: 454 DQRKTSPASLDFPESQKS------SRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSES 507

Query: 327 ELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQ--PP 384
              +S+  +  L   T         P +P L     +  PP      ++P+  +R   P 
Sbjct: 508 PKAASDIWKPVLSIDTE--------PRKPALFPEPAKTAPP------ASPEARKRALFPE 553

Query: 385 QRRHSIEKETP 395
            R+H++  E P
Sbjct: 554 PRKHALFPELP 564


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,634,447
Number of Sequences: 37866
Number of extensions: 1270986
Number of successful extensions: 5945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 5495
Number of HSP's gapped (non-prelim): 662
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.