Search of human proteins with 188497689

Search of human proteins with 188497689

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188497689 chromatin licensing and DNA replication factor 1
[Homo sapiens]
         (546 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188497689 chromatin licensing and DNA replication factor 1 [H...  1083   0.0  
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     46   8e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         45   2e-04
gi|57529222 basic helix-loop-helix domain containing, class B, 4...    44   5e-04
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           43   6e-04
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                43   6e-04
gi|119943102 CREB binding protein isoform b [Homo sapiens]             43   8e-04
gi|119943104 CREB binding protein isoform a [Homo sapiens]             43   8e-04
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    43   8e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    43   8e-04
gi|157266264 pleckstrin homology-like domain, family B, member 3...    43   8e-04
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ...    42   0.001
gi|30795231 brain abundant, membrane attached signal protein 1 [...    42   0.002
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002
gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002
gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]             42   0.002
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       42   0.002
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              41   0.002
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    41   0.002
gi|40254834 kinesin family member 1C [Homo sapiens]                    41   0.002
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    40   0.004
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    40   0.004
gi|6005997 double C2-like domains, beta [Homo sapiens]                 40   0.005
gi|169215350 PREDICTED: hypothetical protein [Homo sapiens]            40   0.007
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    40   0.007
gi|157504499 ankyrin repeat domain 47 [Homo sapiens]                   40   0.007
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    39   0.009
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    39   0.009
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    39   0.009

>gi|188497689 chromatin licensing and DNA replication factor 1 [Homo
           sapiens]
          Length = 546

 Score = 1083 bits (2800), Expect = 0.0
 Identities = 546/546 (100%), Positives = 546/546 (100%)

Query: 1   MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRD 60
           MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRD
Sbjct: 1   MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRD 60

Query: 61  QARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTI 120
           QARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTI
Sbjct: 61  QARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTI 120

Query: 121 SELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPG 180
           SELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPG
Sbjct: 121 SELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPG 180

Query: 181 LPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIK 240
           LPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIK
Sbjct: 181 LPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIK 240

Query: 241 TVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQ 300
           TVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQ
Sbjct: 241 TVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQ 300

Query: 301 KLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTA 360
           KLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTA
Sbjct: 301 KLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTA 360

Query: 361 QEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQ 420
           QEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQ
Sbjct: 361 QEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQ 420

Query: 421 DLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACA 480
           DLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACA
Sbjct: 421 DLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACA 480

Query: 481 RMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQT 540
           RMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQT
Sbjct: 481 RMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQT 540

Query: 541 RAEEGL 546
           RAEEGL
Sbjct: 541 RAEEGL 546


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 34/106 (32%), Positives = 43/106 (40%), Gaps = 15/106 (14%)

Query: 15  PGPPRI-----------APPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQAR 63
           P PPR            APP      P PA  A  APA A   +   A  P +PG  Q  
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPG 168

Query: 64  PPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPP 109
           P A+R   L+    + P  P AP   A P+  ++      AA +PP
Sbjct: 169 PRAQRAAPLA----APPPAPAAPPAVAPPAGPRRAPPPAVAAREPP 210



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 8/92 (8%)

Query: 19  RIAPPKLACRTPSPARPALRAPASATSGS-RKRARPPAAPGRDQARPPARRRLRLSVDEV 77
           R+ PP+     P+P R    APA+A + +      PP  P    A  PAR          
Sbjct: 98  RVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARA-------PR 150

Query: 78  SSPSTPEAPDIPACPSPGQKIKKSTPAAGQPP 109
           ++ +   AP  P    PG + +++ P A  PP
Sbjct: 151 AAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP 182



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 40/155 (25%), Positives = 55/155 (35%), Gaps = 15/155 (9%)

Query: 14  RPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLS 73
           +PGP       LA   P+PA P    PA A     +RA PPA   R+   PP  +     
Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAP----PAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221

Query: 74  VDEVSSPSTPEAPDIPACPSPG---------QKIKKSTPAAGQPPHLTSAQDQDTISELA 124
             +   P  P+ P        G         + ++    + G    LT  + Q  + E A
Sbjct: 222 QQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEA 281

Query: 125 SCLQRARELGARVRALKASAQDAGESCTPEAEGRP 159
           +   R R    R+ AL     D      P A  RP
Sbjct: 282 AA--RGRLERTRLGALALPRGDRPGRAPPAASARP 314



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 46/171 (26%), Positives = 59/171 (34%), Gaps = 15/171 (8%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKR-----ARPPAAPGRDQARPPARRR 69
           P P   A P  A R  + A  A  +P  A  G R +     A PP AP    A  P    
Sbjct: 137 PAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP 196

Query: 70  LRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQR 129
            R     V++   P  P  P  P+P Q+ +   P    PP   + +        A    R
Sbjct: 197 RRAPPPAVAA-REPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVR--------AGGAAR 247

Query: 130 ARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQ-RFHALAQP 179
              L   VR L  S    G       +G  EE    +    + R  ALA P
Sbjct: 248 PVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALP 298



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 16/79 (20%)

Query: 346 AALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRP-------- 397
           AA   PP T         +A A    +PR   A +       AP SPG  +P        
Sbjct: 122 AAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAA------TAPPSPGPAQPGPRAQRAA 175

Query: 398 --ALPATPPATPPAASPSA 414
             A P   PA PPA +P A
Sbjct: 176 PLAAPPPAPAAPPAVAPPA 194


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/89 (37%), Positives = 40/89 (44%), Gaps = 9/89 (10%)

Query: 12  RRRPGPPRIAPPKLACRTPSPARPALRAPA------SATSGSRKRARPPAAPGRDQARPP 65
           RRR  P R+ PP    R+ SP R   R+ A      S++S SR R+ P   P R  + P 
Sbjct: 324 RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPR 383

Query: 66  ARRRLRLSVDEVSSPSTPEAPDIPACPSP 94
             RRL  S    S P     P  PA P P
Sbjct: 384 KTRRLSPS---ASPPRRRHRPSPPATPPP 409



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 44/171 (25%), Positives = 63/171 (36%), Gaps = 23/171 (13%)

Query: 12  RRRPGPPRIAPPKLACRTPSPARPALRAPASAT---SGSRKRARPPAAPGRDQARPPARR 68
           RR P P   APP    RTP+P  P  R P+      S S +R  PP       + PP RR
Sbjct: 558 RRSPSP---APPPRRRRTPTPP-PRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRR 613

Query: 69  RLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQ 128
                    +SP  P        P P +++  S P    P   +S   +     L+S  +
Sbjct: 614 --------TASPPPPPKRRASPSPPPKRRVSHSPP----PKQRSSPVTKRRSPSLSSKHR 661

Query: 129 RARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQP 179
           +        R  ++   +   S +P    RP  P    +P   R  A + P
Sbjct: 662 KGSSPSRSTREARSPQPNKRHSPSP----RPRAPQTSSSPPPVRRGASSSP 708



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 33/99 (33%), Positives = 38/99 (38%), Gaps = 25/99 (25%)

Query: 12  RRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLR 71
           RR P PP    P    R+PSPA P            R+R  P   P R    PP RRR  
Sbjct: 547 RRSPSPP----PTRRRRSPSPAPPP-----------RRRRTPTPPPRRRTPSPPPRRR-- 589

Query: 72  LSVDEVSSPSTPE-APDIPACPSPGQKIKKSTPAAGQPP 109
                  SPS    +P I    SP    K+ T +   PP
Sbjct: 590 -------SPSPRRYSPPIQRRYSPSPPPKRRTASPPPPP 621



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 31/110 (28%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 11  ARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAA----PGRDQARPPA 66
           +R R   P    P+   R+ S +    R P+     S +R  PP      P   ++R P 
Sbjct: 286 SRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345

Query: 67  RRRLRLSVD---EVSSPSTPEAPDIPACP-----SPGQKIKKSTPAAGQP 108
           RRR R S       SS S+  +   P  P     SP +K ++ +P+A  P
Sbjct: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 15/105 (14%)

Query: 13  RRPGPPRIAPPKLACRTP--SPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRL 70
           R P P +   P    R P  S + P +R  AS++   R+   P   P R  +R P  +++
Sbjct: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI 733

Query: 71  RLSVD-------------EVSSPSTPEAPDIPACPSPGQKIKKST 102
           + +                VS    P A   PA PSP Q    ST
Sbjct: 734 KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPST 778



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 13/105 (12%)

Query: 15  PGPPRIAPPKLACRTPSPARPALR--APASATSGSR-----KRARP---PAAPGRDQARP 64
           P P + + P    R+PS +    +  +P+ +T  +R     KR  P   P AP    + P
Sbjct: 639 PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698

Query: 65  PARRRLRLSVDEVSSPSTPEAP--DIPACPSPGQKIKKSTPAAGQ 107
           P RR    S     SPS    P   +   P P +KIKK+   + Q
Sbjct: 699 PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP-KKIKKAASPSPQ 742


>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/162 (28%), Positives = 65/162 (40%), Gaps = 24/162 (14%)

Query: 32  PARPALRAPASATSGS-------------RKRARPPAAPGRDQARPPARRRLRLSVDEVS 78
           PA PA RAPA A   S             R+R R P +    + RP  +R LRLS++   
Sbjct: 50  PAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARE 109

Query: 79  SPSTPEAPD--------IPACPSPG-QKIKK-STPAAGQPPHLTSAQDQDTISELASCLQ 128
                +  D        IP   SP  +K+ K +T    +   L  AQ  D +  L + L 
Sbjct: 110 RRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLN 169

Query: 129 RARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAY 170
           + + L A V A   +       C P + G    PC +K  A+
Sbjct: 170 QGQGLAAPVNAAPLTPFGQATVC-PFSAGAALGPCPDKCAAF 210


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 49/199 (24%), Positives = 73/199 (36%), Gaps = 37/199 (18%)

Query: 16   GPPRIAPPKLACRTP------SPARPALRAPASATSGSRKRARPPAAPGRDQAR------ 63
            G P + P   A  +P       PARP+L  PASA   S  +  PP  P   + R      
Sbjct: 2134 GSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGS 2193

Query: 64   --------------PPARRRLRLSVDEVSSPSTPEA-PDIPACPSPGQKIKKSTPAAGQP 108
                          PP R R    ++   +PS   + P +P+  SPG  +  + P    P
Sbjct: 2194 LAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASP 2253

Query: 109  PHLTSAQDQDTISELASCLQRARELGARVRALKASAQDAGE---SCTPEAEGRPE-EPCG 164
                 +  + T   ++S  +R         +L+A+ Q++GE      P A    +  P  
Sbjct: 2254 ALSEGSSSEATTPVISSVAERFSP------SLEAAEQESGELDPGMEPAAHSLWDLTPLS 2307

Query: 165  EKAPAYQRFHALAQPGLPG 183
               PA         P LPG
Sbjct: 2308 PAPPASLDLALAPAPSLPG 2326



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 16/93 (17%)

Query: 346  AALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSP------RPAL 399
            A  P PP   +     EV        +P ++ +L QL     +PSSPG+P      RPA 
Sbjct: 2203 ALAPGPPTRTRHDEYLEVTK------APSLDSSLPQLP----SPSSPGAPLLSNLPRPAS 2252

Query: 400  PATPPATPPAASPSALKGVSQDLLERIRAKEAQ 432
            PA    +   A+   +  V++     + A E +
Sbjct: 2253 PALSEGSSSEATTPVISSVAERFSPSLEAAEQE 2285



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 18/105 (17%)

Query: 11   ARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRL 70
            A  +P P ++     A   P+   P    PA A + + + A   A P  ++   P     
Sbjct: 2343 ATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAA---ACPAWERGAWPE---- 2395

Query: 71   RLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQ 115
                +  S P T  +P+ P CP+ G         +G PP   S +
Sbjct: 2396 --GAERSSRPDTLLSPEQPVCPAGG---------SGGPPSSASPE 2429


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 15/107 (14%)

Query: 14  RPGPPRI--APPKLAC---------RTPSPARPALRAPASATSGSRKR-ARPPAAPGRDQ 61
           RP  P++  +PP+ A          + P+PARP +  P    SGSR     PP  PG   
Sbjct: 541 RPASPKVTRSPPETAAPVEDMARRTKRPAPARPTM--PPPQVSGSRSSPPAPPLPPGSGS 598

Query: 62  ARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQP 108
              P     RL    + +P+ P  P  P  P P ++  + +PA+  P
Sbjct: 599 PGTPQALPRRLVGSSLRAPTVP-PPLPPTPPQPARRQSRRSPASPSP 644



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 22/105 (20%)

Query: 13  RRPGPPR--IAPPKLACRTPSPARPALRAPASATSGSRK---------RARPPAAPGRDQ 61
           +RP P R  + PP+++    SP  P L  P S + G+ +           R P  P    
Sbjct: 566 KRPAPARPTMPPPQVSGSRSSPPAPPL-PPGSGSPGTPQALPRRLVGSSLRAPTVPPPLP 624

Query: 62  ARP--PARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPA 104
             P  PARR+ R S    +SPS P +P  PA PSP   +  S PA
Sbjct: 625 PTPPQPARRQSRRS---PASPS-PASPG-PASPSP---VSLSNPA 661



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 22/101 (21%)

Query: 17  PPRIAPPKLACRTPSPARPALRAPASATSGSRKRAR---PP--------------AAPGR 59
           P    P       P+PA     APA A++ +++R     PP              AAP  
Sbjct: 500 PSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVE 559

Query: 60  DQAR---PPARRRLRLSVDEVS-SPSTPEAPDI-PACPSPG 95
           D AR    PA  R  +   +VS S S+P AP + P   SPG
Sbjct: 560 DMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPG 600



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 8/81 (9%)

Query: 18  PRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEV 77
           P + PP      P+P +PA R    + +     +  PA+P       PA+  L  +  E 
Sbjct: 617 PTVPPPL----PPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEG 672

Query: 78  SSP----STPEAPDIPACPSP 94
            +P      P  P IP  P P
Sbjct: 673 GAPEAISGVPTPPAIPPQPRP 693


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 36/156 (23%), Positives = 57/156 (36%), Gaps = 16/156 (10%)

Query: 17  PPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDE 76
           PP + PP+       PA P   +   ++SG      P + P   Q +     +       
Sbjct: 836 PPGMTPPQ-------PAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQV 888

Query: 77  VSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTI-------SELASCLQR 129
              P TP  P  P+  +P    ++ TP   QPP    +Q   +I       S +AS    
Sbjct: 889 TPQPQTPVQP--PSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETN 946

Query: 130 ARELGARVRALKASAQDAGESCTPEAEGRPEEPCGE 165
           +++ G  V  L+   +   E   P+      EP  E
Sbjct: 947 SQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 982



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 336  NVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISP-RMEKALSQLALRSAAPS--SP 392
            NV +     P + P    T++ +T Q     A+   SP  M  A      R+  P+  S 
Sbjct: 1838 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1897

Query: 393  GSPRPALPA-TPPATPPAASPSALKGVSQD 421
            G P   +PA  PPA PP A+  A + + ++
Sbjct: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIERE 1927


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 36/156 (23%), Positives = 57/156 (36%), Gaps = 16/156 (10%)

Query: 17   PPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDE 76
            PP + PP+       PA P   +   ++SG      P + P   Q +     +       
Sbjct: 874  PPGMTPPQ-------PAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQV 926

Query: 77   VSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTI-------SELASCLQR 129
               P TP  P  P+  +P    ++ TP   QPP    +Q   +I       S +AS    
Sbjct: 927  TPQPQTPVQP--PSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETN 984

Query: 130  ARELGARVRALKASAQDAGESCTPEAEGRPEEPCGE 165
            +++ G  V  L+   +   E   P+      EP  E
Sbjct: 985  SQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 1020



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 336  NVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISP-RMEKALSQLALRSAAPS--SP 392
            NV +     P + P    T++ +T Q     A+   SP  M  A      R+  P+  S 
Sbjct: 1876 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1935

Query: 393  GSPRPALPA-TPPATPPAASPSALKGVSQD 421
            G P   +PA  PPA PP A+  A + + ++
Sbjct: 1936 GKPTSQVPAPPPPAQPPPAAVEAARQIERE 1965


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 43/191 (22%), Positives = 72/191 (37%), Gaps = 19/191 (9%)

Query: 29  TPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDE--VSSPSTPEAP 86
           +P P RP  R P+   S SR  + PP  P      PP    + +  ++  V  P++  AP
Sbjct: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAP 852

Query: 87  DIPACPSPGQKIKKSTPAAGQP--PHLTSAQDQDTISELASCLQRARELGARVRALKASA 144
             P  P P  + +   P    P  PHL         S  +S +  + E  +R   L A  
Sbjct: 853 TAPGPPQPPLRPQSQPPEGPLPPAPHLPP-------SSTSSAVASSSETSSR---LPAPT 902

Query: 145 QDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPGLPGLVLPYKYQVLAEMFRSMDTIV 204
               +   P ++G  + P           H + +P  P    P  +Q++   F ++    
Sbjct: 903 PSDFQLQFPPSQGPHKSPTPPPT-----LHLVPEPAAPPPPPPRTFQMVTTPFPALPQPK 957

Query: 205 GMLHNRSETPT 215
            +L    + P+
Sbjct: 958 ALLERFHQVPS 968



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 32/125 (25%), Positives = 44/125 (35%), Gaps = 32/125 (25%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQAR---PPARRRLR 71
           P P   APP+    TP P+     +P     G    A P A   +D  +   P  R +  
Sbjct: 651 PTPQAAAPPQAT--TPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQP 708

Query: 72  LSVDE----------VSSPST-----------------PEAPDIPACPSPGQKIKKSTPA 104
           LS +           VS+P                   P+APD  A P+P  +I  + P 
Sbjct: 709 LSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPL 768

Query: 105 AGQPP 109
            G  P
Sbjct: 769 KGPGP 773



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 40/164 (24%), Positives = 58/164 (35%), Gaps = 36/164 (21%)

Query: 21  APPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEVSSP 80
           A P L  +    A PA+  P        +  +PP AP    A PP               
Sbjct: 615 AAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP-------------QA 661

Query: 81  STPEAPDIPACPSPGQKIKKSTPAAGQPPHL--TSAQDQDTISELASCLQRARELGAR-- 136
           +TP+       PSPG          GQPP    T+   QD++       +  + L A   
Sbjct: 662 TTPQ-------PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP 714

Query: 137 --------VRALKASAQDAGESCTPEAEGR---PEEPCGEKAPA 169
                   + +    AQD   + TP A+G    P+ P  + +PA
Sbjct: 715 HLSVPASVIVSAPPPAQDPAPA-TPVAKGAGLGPQAPDSQASPA 757



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 1/70 (1%)

Query: 339 EVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPA 398
           ++P   P   P P ++  L   Q  L  + +L SP   +  S+   R  + S P S  P 
Sbjct: 761 QIPAAAPLKGPGPSSSPSLPH-QAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPL 819

Query: 399 LPATPPATPP 408
            P  PP  PP
Sbjct: 820 HPCPPPQAPP 829



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 41/180 (22%), Positives = 61/180 (33%), Gaps = 31/180 (17%)

Query: 15   PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSV 74
            P  P + P   +    S +  + R PA   S  + +  P   P +    PP       ++
Sbjct: 874  PPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP-------TL 926

Query: 75   DEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRARELG 134
              V  P+ P  P     P   Q +    PA  QP  L      +   ++ S +    + G
Sbjct: 927  HLVPEPAAPPPPP----PRTFQMVTTPFPALPQPKALL-----ERFHQVPSGIILQNKAG 977

Query: 135  ARVRALKASAQDAGESCTPEA---------EGRPEEPCGEKAPAYQRFHALAQPGLPGLV 185
                A + S    G   +P A          G P  P    APA      +A  GLP L+
Sbjct: 978  GAPAAPQTST-SLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA-----PMAATGLPPLL 1031



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 4/70 (5%)

Query: 344 EPAALPQPPA-T-EKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPA 401
           EPAA P PP  T + +TT    L + + L+  R  +  S + L++ A  +P +P+ +  +
Sbjct: 931 EPAAPPPPPPRTFQMVTTPFPALPQPKALLE-RFHQVPSGIILQNKAGGAPAAPQTS-TS 988

Query: 402 TPPATPPAAS 411
             P T PAAS
Sbjct: 989 LGPLTSPAAS 998


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 9/112 (8%)

Query: 20   IAPPKLACRTPSPAR-PALRAP--ASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDE 76
            + PP  A   PSP + PA+  P  A AT  S++ + PPA         P+ + L L    
Sbjct: 1548 LIPP--AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL-LIPPA 1604

Query: 77   VSSPSTPEAPDIPACPSPGQKIKKSTPA-AGQP--PHLTSAQDQDTISELAS 125
            V+SPS  EAP  PA   P  +   +TPA  G P  P +T +  +D+ +  AS
Sbjct: 1605 VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 37/158 (23%), Positives = 52/158 (32%), Gaps = 22/158 (13%)

Query: 17   PPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPA------------APGRDQARP 64
            PP    P     TP   +  L  P    + +   A PP+            AP    A P
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179

Query: 65   PARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELA 124
            P+ +        +++PS   AP  PA   P  K   +TP+    P   +A        LA
Sbjct: 1180 PSPK------GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233

Query: 125  SCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEP 162
            +   +    GA            G   TP  +G P  P
Sbjct: 1234 TPSPK----GAPTTPAATPPSPKGGPATPPPKGAPTPP 1267



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 42/154 (27%), Positives = 49/154 (31%), Gaps = 16/154 (10%)

Query: 15   PGPPRIAP--PKLACRTPSP---ARPALRAPASATSGSRKRARPPAAPGRDQARPPARRR 69
            P PP   P  PK    TPSP     P    P S   G    + P  AP    A PP+ + 
Sbjct: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS-PKGAPTPPAATPPSPK- 997

Query: 70   LRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDT-ISELASCLQ 128
                      P+TP     P  P+      K +PAA   P   S     T  S   S   
Sbjct: 998  --------GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049

Query: 129  RARELGARVRALKASAQDAGESCTPEAEGRPEEP 162
                 GA            G   TP  +G P  P
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 90/410 (21%), Positives = 143/410 (34%), Gaps = 50/410 (12%)

Query: 17   PPRIAPPKLACRTPSPARPALRAPAS--ATSGSRKRARPPAAPGRDQARPPARRRLRLSV 74
            PP + P  L         PA  AP    AT  S+     PA        PPA +++  S 
Sbjct: 1435 PPAVTPVSLK------KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488

Query: 75   DEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRARELG 134
                +P+TP     P  P+      K  PA       T +  +D I+  A+ L  +++  
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPA-------TPSSRRDPIAPTATLL--SKKTP 1539

Query: 135  ARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPGLPGLVLPYKYQVLA 194
            A +   +A    A     P  +  P  P  ++APA     +  +   P  V P  Y+   
Sbjct: 1540 ATLAPKEALIPPA--MTVPSPKKTPAIPTPKEAPATP---SSKEASSPPAVTPSTYKGAP 1594

Query: 195  EMFRSMDTIVGMLHNRSETPTFAKV-----QRGVQDMMRR---RFEECNVGQIK--TVYP 244
                 +        +  E PT   V     ++G      +            +K     P
Sbjct: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654

Query: 245  ASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTA----SRLLQRRQIFSQ 300
            AS   +   +VP    G         ++ +L   A  + P +TA        ++    S 
Sbjct: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714

Query: 301  KLV--EHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLT 358
             +      K   K  L++++PA ++P  + +    +          P A P+  A+  LT
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774

Query: 359  TAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPP 408
             A      A   + P+ E A       SAAPS P S  P  P+  P  PP
Sbjct: 1775 AA------AFEKVLPKPESASV-----SAAPSPPVS-LPLAPSPVPTLPP 1812



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 33/116 (28%), Positives = 44/116 (37%), Gaps = 20/116 (17%)

Query: 15   PGPPRIAPPKLACRTPSPARPALRAPASATSGSRK----RARPPAAPGRDQARPPARRRL 70
            P PP   PP L     +P       PA  T  S K     + P  AP    A PP+ +  
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK-- 1321

Query: 71   RLSVDEVSSPSTPE---APDIPACPSPGQK----IKKSTPAAGQPPHLTSAQDQDT 119
                    SP TP    AP  PA   P  K    +  +TP++   P   S+++  T
Sbjct: 1322 -------GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 345  PAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPAL---PA 401
            PAA P  P    L T     A      +P   K          AP++P +  P+    PA
Sbjct: 1198 PAATPPSPKGG-LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256

Query: 402  TPPA----TPPAASPSALKG 417
            TPP     TPPAA+P +LKG
Sbjct: 1257 TPPPKGAPTPPAATPPSLKG 1276



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 38/118 (32%), Positives = 47/118 (39%), Gaps = 28/118 (23%)

Query: 17  PPRIAPPKLACRTP----SPARPALR-APA-SATSGSRKRAR-------------PPAAP 57
           PP+  P       P     PA PA + APA S TS S K+AR             P  AP
Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940

Query: 58  GRDQARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPA---AGQPPHLT 112
               A PP+ +         ++PS   AP  PA   P  K   +TP+   A  PP  T
Sbjct: 941 TPPAATPPSPK------GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 44/171 (25%), Positives = 57/171 (33%), Gaps = 27/171 (15%)

Query: 15   PGPPRIAP--PKLACRTPS----PARPALRAPA-----SATSGSRKRARPPAAPGRDQAR 63
            P PP   P  PK    TPS    P  PA+  P+     +AT   +  + PPAA       
Sbjct: 986  PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045

Query: 64   PPARRRLRLSVDEV------------SSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHL 111
             PA   L                   ++PS   AP  PA   P  K   +TP+    P  
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105

Query: 112  TSAQDQDTISELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEP 162
             +A        LA+   +    GA            G   TP  +G P  P
Sbjct: 1106 PAATPPSPKGGLATPPHK----GAPTTPAATPPSPKGGLATPPPKGAPTTP 1152



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 15/93 (16%)

Query: 339 EVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPA 398
           E P      LP P         ++  A +    SP+  +A        A+PS  G+P P 
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943

Query: 399 LPATPPA--------------TPPAASPSALKG 417
             ATPP+              TPPAA+P + KG
Sbjct: 944 -AATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 33/157 (21%), Positives = 53/157 (33%), Gaps = 30/157 (19%)

Query: 15   PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAA----PGRDQARPPARRRL 70
            P PP + PP        PA          T  S++   PPAA     G     PP+ +R 
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392

Query: 71   RLSVDEVSSPSTPEAPDIPACPSPGQKIKK---STPAAGQ--PPHLTSAQDQDTISELAS 125
                     P++P    +    +P   + +   +TP+ G   PP +T             
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS---------- 1442

Query: 126  CLQRARELGARVRALKASAQDAGESCTPEAEGRPEEP 162
                       ++   A++   G   TP ++G P  P
Sbjct: 1443 -----------LKKAPATSAPKGGPATPSSKGDPTLP 1468



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 14/90 (15%)

Query: 340  VPDIEPAALPQPPATEKLTTAQEVLARARNLISPRM------EKALSQLALRSAAPS-SP 392
            +P + P++  + PAT   ++ ++ +A    L+S +       ++AL   A+   +P  +P
Sbjct: 1505 LPAVIPSSPKEVPATP--SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562

Query: 393  GSPRPA-LPATPPA----TPPAASPSALKG 417
              P P   PATP +    +PPA +PS  KG
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 13/86 (15%)

Query: 345  PAALPQPPATEK------LTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPA 398
            P   P PPA         L T     A    +++P   K     +    AP+ P +  P+
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319

Query: 399  ---LPATPPA----TPPAASPSALKG 417
                P TPP     TPPA +P + KG
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKG 1345



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 5/78 (6%)

Query: 341  PDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPR-PAL 399
            P   PAA P P        A     +     +P  + A +  A  +  PS  G P  P+L
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA--ATLPSPKGGPATPSL 1076

Query: 400  PATPPATPPAASPSALKG 417
               P  TPPAA+P + KG
Sbjct: 1077 KGAP--TPPAATPPSPKG 1092



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 30/97 (30%), Positives = 37/97 (38%), Gaps = 18/97 (18%)

Query: 15   PGPPRIAPP--KLACRTPSPARPALRAPAS---ATSGSRKRARPPAAPGRDQARPPARRR 69
            P  P   PP  K    TPSP + A   PA+   +  G      P  AP    A PP+ + 
Sbjct: 1195 PTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK- 1252

Query: 70   LRLSVDEVSSPSTPE---APDIPACPSPGQKIKKSTP 103
                      P+TP    AP  PA   P  K   +TP
Sbjct: 1253 --------GGPATPPPKGAPTPPAATPPSLKGGLATP 1281



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 20/86 (23%)

Query: 345  PAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPAL----- 399
            PAA P  P     T   +          P ++  L       A P   G+P PA+     
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL-------ATPPHKGAPNPAVVTPPS 1296

Query: 400  ----PATPPA----TPPAASPSALKG 417
                PAT P     TPPAA+P + KG
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKG 1322


>gi|157266264 pleckstrin homology-like domain, family B, member 3
           [Homo sapiens]
          Length = 640

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 43/144 (29%), Positives = 65/144 (45%), Gaps = 9/144 (6%)

Query: 340 VPDIEPAALPQP-PATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPA 398
           VP+ +    PQ  P   +   A EVLA   +      +    ++   S+  SS  +P   
Sbjct: 16  VPECDVEVQPQGHPEESREQEASEVLAEPSSRGGAEQQAEEEEVGEGSSTESSRDAPEAT 75

Query: 399 LPATPPATPPAASPSALKGVSQDLLERIRAKEAQ-KQLAQMTRCPEQEQRLQRLERLPEL 457
            P    ATPP AS S+ +GV      R  A+  Q +QL  +TR    EQR++ L+R  + 
Sbjct: 76  PPIAMAATPP-ASTSSREGV------RGAARRLQGQQLEALTRVALMEQRVKELQRQRKE 128

Query: 458 ARVLRSVFVSERKPALSMEVACAR 481
            R+   V V+  +  L+ E   AR
Sbjct: 129 LRIEMEVEVALLRGELAGERVAAR 152


>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
           sapiens]
          Length = 776

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 2/103 (1%)

Query: 13  RRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRL 72
           R   PP       A R P+   PA + P S+ +   +R  PPA P  ++  PP +   R 
Sbjct: 472 RGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPP-KSGDRS 530

Query: 73  SVDEVSSPSTPEAPD-IPACPSPGQKIKKSTPAAGQPPHLTSA 114
                 SP TP +    P+ P+P  +  K       PP   S+
Sbjct: 531 GYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS 573


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/145 (24%), Positives = 56/145 (38%), Gaps = 30/145 (20%)

Query: 40  PASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIK 99
           P      +  +A PP AP ++QA P             +    P+A +  A P+     +
Sbjct: 87  PEKTEGAAEAKAEPPKAPEQEQAAP----------GPAAGGEAPKAAEAAAAPA-----E 131

Query: 100 KSTPAAGQPPHLTSAQDQDTISELASCLQRARELGARVRALKASAQDA------------ 147
            + PAAG+ P     + + T +  A   Q  +  GA     K  + +A            
Sbjct: 132 SAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATE 191

Query: 148 GESCTPEAEG---RPEEPCGEKAPA 169
             S TP+A+G     EEP   +APA
Sbjct: 192 APSSTPKAQGPAASAEEPKPVEAPA 216


>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 27/67 (40%), Positives = 33/67 (49%), Gaps = 5/67 (7%)

Query: 30  PSPARPALRAPASATSGSRKRARPP---AAPGRDQARPPARRRLRLSVDE--VSSPSTPE 84
           PSP RP    PASA   S   AR P   A PG  + R  A R   +  D+  V++P  PE
Sbjct: 149 PSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPE 208

Query: 85  APDIPAC 91
            P +P C
Sbjct: 209 RPRVPFC 215


>gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 27/67 (40%), Positives = 33/67 (49%), Gaps = 5/67 (7%)

Query: 30  PSPARPALRAPASATSGSRKRARPP---AAPGRDQARPPARRRLRLSVDE--VSSPSTPE 84
           PSP RP    PASA   S   AR P   A PG  + R  A R   +  D+  V++P  PE
Sbjct: 149 PSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPE 208

Query: 85  APDIPAC 91
            P +P C
Sbjct: 209 RPRVPFC 215


>gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 27/67 (40%), Positives = 33/67 (49%), Gaps = 5/67 (7%)

Query: 30  PSPARPALRAPASATSGSRKRARPP---AAPGRDQARPPARRRLRLSVDE--VSSPSTPE 84
           PSP RP    PASA   S   AR P   A PG  + R  A R   +  D+  V++P  PE
Sbjct: 149 PSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPE 208

Query: 85  APDIPAC 91
            P +P C
Sbjct: 209 RPRVPFC 215


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 41/137 (29%), Positives = 53/137 (38%), Gaps = 10/137 (7%)

Query: 15  PGPP-RIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLS 73
           P PP R APP   C++P P R +   P  +    R  A P       Q R P     +  
Sbjct: 350 PSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSP 409

Query: 74  VDEVSSPSTPEA----PDIPACPSPGQKIKKSTPAAGQPPHLTSA--QDQDTISELASCL 127
             +  SP  P      P  P  P PG++       A  P H   A  Q + + SELA   
Sbjct: 410 SPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELA--- 466

Query: 128 QRARELGARVRALKASA 144
           + A   GA    L+A A
Sbjct: 467 EGAAYAGASPPWLQAEA 483


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)

Query: 17  PPRIAPPKLACRTPSPARPALRAPASATSG-SRKRARPPAAPGRDQARPPARRRLRLSVD 75
           P   +PP    R+P+PA PAL APA      S   A P + P       P +    +S D
Sbjct: 667 PAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726

Query: 76  EVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQ 107
           +   PS P +   P  P+   ++    P+A +
Sbjct: 727 QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE 758



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%)

Query: 52   RPPAAPGRD-QARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPG 95
            RPP AP +  +A PP  R+  + V   +SPS P A  + A P+ G
Sbjct: 1010 RPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNG 1054



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 2/69 (2%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPAR-RRLRLS 73
           PG  R  PP+   RT SP+        + T   +  A PPA+PG+ Q   P R   LR  
Sbjct: 564 PGGSR-RPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSP 622

Query: 74  VDEVSSPST 82
              VSS  T
Sbjct: 623 GASVSSSLT 631


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 11/97 (11%)

Query: 14  RPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLS 73
           RPG P   PP+   ++  P     +     + G  K   PP  PG+ Q  PP        
Sbjct: 200 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPP-------- 251

Query: 74  VDEVSSPSTPEAPDIPACPSP--GQKIKKSTPAAGQP 108
             E + P  P  P  P  P P  G   +   P AG+P
Sbjct: 252 -QEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKP 287



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 6/95 (6%)

Query: 14  RPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLS 73
           RPG P   PP+   ++  P     +       G  +   PP  PG+ +  PP  +    S
Sbjct: 74  RPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPP--QGGNQS 131

Query: 74  VDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQP 108
                 P  PE P     P  G + +   P  G+P
Sbjct: 132 QGPPPRPGKPEGPP----PQGGNQSQGPPPRPGKP 162



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 6/95 (6%)

Query: 14  RPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLS 73
           RPG P   PP+   ++  P     +       G  +   PP  PG+ +  PP  +    S
Sbjct: 116 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP--QGGNQS 173

Query: 74  VDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQP 108
                 P  PE P     P  G + +   P  G+P
Sbjct: 174 QGPPPHPGKPEGPP----PQGGNQSQGPPPRPGKP 204



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 6/94 (6%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSV 74
           PG P   PP+   ++  P     +       G  +   PP  PG+ + +PP  +    S 
Sbjct: 54  PGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPP--QGGNQSQ 111

Query: 75  DEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQP 108
                P  PE P     P  G + +   P  G+P
Sbjct: 112 GPPPRPGKPEGPP----PQGGNQSQGPPPRPGKP 141



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 26/97 (26%), Positives = 34/97 (35%), Gaps = 12/97 (12%)

Query: 14  RPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLS 73
           RPG P   PP+   ++  P     +       G  +   PP  PG+ +  PP  +    S
Sbjct: 158 RPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP--QGGNQS 215

Query: 74  VDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPH 110
                 P  PE P     PS G          G PPH
Sbjct: 216 QGPPPRPGKPEGP-----PSQG-----GNKPQGPPPH 242


>gi|40254834 kinesin family member 1C [Homo sapiens]
          Length = 1103

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 64/274 (23%), Positives = 117/274 (42%), Gaps = 41/274 (14%)

Query: 259 KDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQKLVEHVKEHHK-AFLASL 317
           K+G   +    T+  ++   AD  + +  +  +  R  + +  L E++  + + A +A+L
Sbjct: 266 KEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAAL 325

Query: 318 SPAMVVPEDQLTRWHPRFNVDEVPDIE-PAALPQPPATEKLTTAQEVLARARNLISPRME 376
           SPA +  E+ L+        D    I   A + + P    +   QE +AR R L+   M 
Sbjct: 326 SPADINYEETLSTLR---YADRTKQIRCNAIINEDPNARLIRELQEEVARLRELL---MA 379

Query: 377 KALSQLAL----------RSAAPSSPGSPRPALPATPPA----TPPAASPSALKGVS-QD 421
           + LS  AL          R A P+    P P  P++P        P+ SP+    +  ++
Sbjct: 380 QGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEE 439

Query: 422 LLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACAR 481
            +ER+  +E +K +A++      E++L++ E L             ER+  L+      R
Sbjct: 440 AMERL--QETEKIIAELNE--TWEEKLRKTEALR-----------MEREALLAEMGVAVR 484

Query: 482 MVGSCCTIMSPGEMEKHLLLLSE--LLPDWLSLH 513
             G    + SP +   HL+ L+E  L+ + L  H
Sbjct: 485 EDGGTVGVFSP-KKTPHLVNLNEDPLMSECLLYH 517


>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 175

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 18/99 (18%)

Query: 13  RRPGPP--RIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRL 70
           R P PP  R  P     R PSPA   LR P +A  G R+RA   AA  R + +    RRL
Sbjct: 55  RHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPG-RQRADEGAAAARPERQRVWARRL 113

Query: 71  RLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPP 109
                          P   A P+PG+   +  P    PP
Sbjct: 114 ---------------PGSAAAPAPGRDALRLPPPPPPPP 137


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 8/72 (11%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRA---PASATSGSRKRARPPAAPGRDQARPPARRRLR 71
           P PP ++PP L    P PA+        P    + SRKR RPP  P +   R  AR    
Sbjct: 431 PPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAAR---- 486

Query: 72  LSVDEVSSPSTP 83
            +  E +SP TP
Sbjct: 487 -AGPEGTSPPTP 497



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 14/78 (17%)

Query: 14   RPGPPRIAPPK---LACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRL 70
            RP PP   PP    L+    SP R A+R    +T   R    PPA        PP  +  
Sbjct: 2250 RPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRS---PPA--------PPPYKAP 2298

Query: 71   RLSVDEVSSPSTPEAPDI 88
            RL  D  +S  TP+ P +
Sbjct: 2299 RLDEDGEASEDTPQVPGL 2316



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 33/113 (29%), Positives = 40/113 (35%), Gaps = 23/113 (20%)

Query: 17  PPRIA-----PPKLACRTPSP--------ARPALRAPASATSGSRKRARPPAAPGRDQAR 63
           PPR+A     PPK   R            A   L   A A    R RA  P+ P R + R
Sbjct: 163 PPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGR 222

Query: 64  PPAR-----RRLRLSVDEVSSPST-----PEAPDIPACPSPGQKIKKSTPAAG 106
           PP R     RR + +V    +  T     P  P +P     G    K  P  G
Sbjct: 223 PPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPG 275



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 32/113 (28%), Positives = 36/113 (31%), Gaps = 33/113 (29%)

Query: 15  PGPPRI-APPKLACRTPSPARPALRAPASA-TSGSRK------------RARPPAAPGRD 60
           P PPR   PP      P   R  LR P    TS +R+               PP AP   
Sbjct: 581 PSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATS 640

Query: 61  QARP---------PARRRLR----------LSVDEVSSPSTPEAPDIPACPSP 94
             RP         P+   L+          L   E   P  P A D PA P P
Sbjct: 641 SRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEP 693



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 34/136 (25%), Positives = 42/136 (30%), Gaps = 22/136 (16%)

Query: 52  RPPAAPGRDQARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKS---------- 101
           +PP        RPP      +  +    PS P AP  P+ P P  + ++S          
Sbjct: 553 KPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWT 612

Query: 102 --------TPAAGQPPHLTSAQDQDTISELASCLQRARELGARVRALKASAQDAGESCTP 153
                    P A  PP   S       S     L RA +       LK          TP
Sbjct: 613 SLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE----SVLTP 668

Query: 154 EAEGRPEEPCGEKAPA 169
              G PE P  E  PA
Sbjct: 669 PPLGAPEAPEPEPPPA 684



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 22/68 (32%), Positives = 26/68 (38%), Gaps = 3/68 (4%)

Query: 344 EPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATP 403
           EPA +P PP      +    L   R  I        + L  R   P  P  P P  P+ P
Sbjct: 576 EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLT-RELPPPPPAPPPPPAPSPP 634

Query: 404 PATPPAAS 411
           PA  PA S
Sbjct: 635 PA--PATS 640


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 48/185 (25%), Positives = 65/185 (35%), Gaps = 37/185 (20%)

Query: 15  PGP------PRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARR 68
           PGP      P +APP + C  P P  P    P            PPA+   D+A  P   
Sbjct: 204 PGPLTKGNLPVVAPP-VPCAPPPPPPPPPPTPPPL---------PPASVLSDKAVKPQLA 253

Query: 69  RLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPA--AGQPPHLTSAQDQDTISELASC 126
            L L       P  P  P +P C  PG K + ++PA  A +PP          +   ASC
Sbjct: 254 PLHLP------PIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP-----APPPPLPPYASC 302

Query: 127 LQRARELGARVRALKASAQ--------DAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQ 178
             RA      +  + +S++               P+  G    P     P  Q F    +
Sbjct: 303 SPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKR 362

Query: 179 PGLPG 183
            G PG
Sbjct: 363 HGRPG 367



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 5/79 (6%)

Query: 333 PRFNVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQL-ALRSAAPSS 391
           PR NV   P   P   P PP    L ++  +      L+SP        L  +    P +
Sbjct: 167 PRPNVPAPPPPTPPP-PPPPLPPPLPSSSPIKTP---LVSPPGPLTKGNLPVVAPPVPCA 222

Query: 392 PGSPRPALPATPPATPPAA 410
           P  P P  P TPP  PPA+
Sbjct: 223 PPPPPPPPPPTPPPLPPAS 241



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 14/41 (34%), Positives = 15/41 (36%)

Query: 372 SPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASP 412
           SPR+            AP  P  P P  P  PP  PP   P
Sbjct: 149 SPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPP 189



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 6/98 (6%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRL-S 73
           P PP + PP      P P  P+   P S  + S +RA P    GR       ++  RL  
Sbjct: 6   PPPPPLPPPPPPLGAPPPPPPS-APPVSTDTSSLRRADP---KGRSALLADIQQGTRLRK 61

Query: 74  VDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHL 111
           V +++  S P+          G     +T  A  PP L
Sbjct: 62  VTQINDRSAPQIESSKGTNKEGGG-SANTRGASTPPTL 98


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 40/124 (32%), Positives = 52/124 (41%), Gaps = 11/124 (8%)

Query: 292 LQRRQIFSQKLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQP 351
           L+RR    +K    ++EH       + P  + P  Q++ + PRF     PD  P A   P
Sbjct: 3   LRRR---GEKATISIQEH---MAIDVCPGPIRPIKQISDYFPRFPRGLPPDAGPRAAAPP 56

Query: 352 PATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPG-SPRPALPATPPATPPAA 410
            A  +   A    A  R+      E       L  A  SSPG SP P+ PA PPA PP  
Sbjct: 57  DAPARPAVAG---AGRRSPSDGAREDDEDVDQLFGAYGSSPGPSPGPS-PARPPAKPPED 112

Query: 411 SPSA 414
            P A
Sbjct: 113 EPDA 116



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 14/78 (17%)

Query: 4   RRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPA--SATSGSRK------------ 49
           ++++D+F R   G P  A P+ A    +PARPA+      S + G+R+            
Sbjct: 31  KQISDYFPRFPRGLPPDAGPRAAAPPDAPARPAVAGAGRRSPSDGAREDDEDVDQLFGAY 90

Query: 50  RARPPAAPGRDQARPPAR 67
            + P  +PG   ARPPA+
Sbjct: 91  GSSPGPSPGPSPARPPAK 108


>gi|169215350 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 707

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 21/100 (21%)

Query: 17  PPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDE 76
           PPR+ PP   CR  SP  P    P    S    R +PPAA        PA   LR+    
Sbjct: 501 PPRVQPP---CRVSSP--PPRVQPPCRVSSPLPRVQPPAAC-------PAPL-LRVQPPA 547

Query: 77  VSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQD 116
           VSSP        PACP+P  +  +S     QP  ++   D
Sbjct: 548 VSSP--------PACPAPATQGSRSQQPTVQPASVSGVLD 579


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 37/159 (23%), Positives = 56/159 (35%), Gaps = 12/159 (7%)

Query: 12  RRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLR 71
           R  PG P+  PP+   +   P  P  +       G +K   PP  PG+ Q  PP   + R
Sbjct: 152 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP-PGKPQGPPPQGDKSR 210

Query: 72  LSVDEVSSP--------STPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISEL 123
            S      P        + P+ P  P     G   +      G PP     + Q   ++ 
Sbjct: 211 SSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP---PGKPQGPPAQG 267

Query: 124 ASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEP 162
            S  Q AR    + +       +  +   P A G P++P
Sbjct: 268 GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 27/95 (28%), Positives = 36/95 (37%), Gaps = 11/95 (11%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSV 74
           PG P+  PP    ++ SP  P  +       G  +   PP  PG+ Q  PP   +     
Sbjct: 135 PGKPQ-GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK----- 188

Query: 75  DEVSSPSTPEAPDIPACPSP-GQKIKKSTPAAGQP 108
                P  P  P  P  P P G K + S    G+P
Sbjct: 189 ----KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 11/95 (11%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSV 74
           PG P+  PP    ++ SP  P  +       G  +   PP  PG+ Q  PP         
Sbjct: 74  PGKPQ-GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP--------- 123

Query: 75  DEVSSPSTPEAPDIPACPSP-GQKIKKSTPAAGQP 108
              + P  P  P  P  P P G K +      G+P
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 158



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 8/97 (8%)

Query: 12  RRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLR 71
           R  PG P+  PP+   +   P  P  +       G  +   PP  PG+ Q  PP   + R
Sbjct: 91  RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP-PGKPQGPPPQGDKSR 149

Query: 72  LSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQP 108
                 S P  P+ P     P  G + +   P  G+P
Sbjct: 150 ---SPRSPPGKPQGPP----PQGGNQPQGPPPPPGKP 179



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 22/79 (27%), Positives = 28/79 (35%), Gaps = 10/79 (12%)

Query: 31  SPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEVSSPSTPEAPDIPA 90
           SP+  A      +  G  K   PP  PG+ Q  PP            + P  P  P  P 
Sbjct: 28  SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPP---------QGGNKPQGPPPPGKPQ 78

Query: 91  CPSP-GQKIKKSTPAAGQP 108
            P P G K +      G+P
Sbjct: 79  GPPPQGDKSRSPRSPPGKP 97


>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
          Length = 821

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 52/183 (28%), Positives = 72/183 (39%), Gaps = 38/183 (20%)

Query: 11  ARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPG-RDQARP----- 64
           ARR PGPP    P    R P P     R+P + TS     +    APG   Q  P     
Sbjct: 61  ARRAPGPPTSRRP----RAPRPGLAGARSPGAWTSSESLASDDGGAPGILSQGAPSGLLM 116

Query: 65  -------PARR-RLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQ--------P 108
                  P R  R+  ++ E +S     A      PSPG+ + +S   +G+        P
Sbjct: 117 QPLSPRAPVRNPRVEHTLRE-TSRRLELAQTHERAPSPGRGVPRSPRGSGRSSPAPNLAP 175

Query: 109 PHLTSAQDQDTISELASCLQRAR----------ELGARVRALKA-SAQDAGESCTPEAEG 157
                AQ Q    ++A+ L+R R          EL  +VRAL+A  A+       PE +G
Sbjct: 176 ASPGPAQLQLVREQMAAALRRLRELEDQARTLPELQEQVRALRAEKARLLAGRAQPEPDG 235

Query: 158 RPE 160
             E
Sbjct: 236 EAE 238



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 12/139 (8%)

Query: 28  RTPSPARPALRAPASATSGSRKRARPPAAPGRDQAR------PPARRRLRLSVDEVSSPS 81
           R PSP R   R+P  +   S      PA+PG  Q +        A RRLR   D+  + +
Sbjct: 149 RAPSPGRGVPRSPRGSGRSSPAPNLAPASPGPAQLQLVREQMAAALRRLRELEDQ--ART 206

Query: 82  TPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRARELGARVRALK 141
            PE  +         + +K+   AG+       + +    +LA   +    L    R  +
Sbjct: 207 LPELQE----QVRALRAEKARLLAGRAQPEPDGEAETRPDKLAQLRRLTERLATSERGGR 262

Query: 142 ASAQDAGESCTPEAEGRPE 160
           A A    +S    A GR E
Sbjct: 263 ARASPRADSPDGLAAGRSE 281


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 49/175 (28%), Positives = 59/175 (33%), Gaps = 27/175 (15%)

Query: 15  PGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPP-------AR 67
           PGPP   PP    + P P  P    P    +       PP  P R +A PP        R
Sbjct: 20  PGPPPPPPPAPPQQQPPPPPPPAPPPGPGPA-------PPQHPPRAEALPPEAADEGGPR 72

Query: 68  RRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCL 127
            RLR        P TP A    A  SP  +  +     G+P    +  +        S  
Sbjct: 73  GRLRSRDSSCGRPGTPGAAS-TAKGSPNGECGR-----GEPQCSPAGPEGPARGPKVSFS 126

Query: 128 QRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQR-FHALAQPGL 181
            R    G       A      E    E  G   EP G +A   QR F AL QPG+
Sbjct: 127 CRGAASG------PAPGPGPAEEAGSEEAGPAGEPRGSQASFMQRQFGALLQPGV 175



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 37/122 (30%), Positives = 45/122 (36%), Gaps = 25/122 (20%)

Query: 11  ARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQA-------- 62
           AR   GP  +  P+L  R P        APA+A+ G    A PP AP   +A        
Sbjct: 743 ARPLVGPLALGSPRLVRRPPPGP-----APAAASPGPPPPASPPGAPASPRAPRTSPYGG 797

Query: 63  ---------RPPARRRLRLSVD-EVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLT 112
                      PARR  R S     S PS P     PA  +  +    STP  G  P   
Sbjct: 798 LPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGPAAST--RPASSSTPRLGPTPAAR 855

Query: 113 SA 114
           +A
Sbjct: 856 AA 857



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 12/85 (14%)

Query: 345 PAALPQPPATEKLTTAQEVLAR------ARNLISPRMEKALSQLALR-----SAAPSSPG 393
           P   P P  T  + T Q+  A       AR L+ P +     +L  R     + A +SPG
Sbjct: 715 PPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGP-LALGSPRLVRRPPPGPAPAAASPG 773

Query: 394 SPRPALPATPPATPPAASPSALKGV 418
            P PA P   PA+P A   S   G+
Sbjct: 774 PPPPASPPGAPASPRAPRTSPYGGL 798


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 13/134 (9%)

Query: 12  RRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLR 71
           R  P PP    P  A   P P+RP++  P    +       PPA P    + PP      
Sbjct: 307 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPN-RMYPPPPPALPSSAPSGPPPPPPSV 365

Query: 72  LSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELASCLQRAR 131
           L V  V+ P  P  P     P PG       P+ G     T+A ++      A+ L + R
Sbjct: 366 LGVGPVAPPPPPPPP-----PPPGPPPPPGLPSDGDHQVPTTAGNK------AALLDQIR 414

Query: 132 ELGARVRALKASAQ 145
           E GA+++ ++ +++
Sbjct: 415 E-GAQLKKVEQNSR 427



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 38/144 (26%), Positives = 56/144 (38%), Gaps = 31/144 (21%)

Query: 341 PDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPAL- 399
           P   P A P PP   + + A  V     N + P    AL      S+APS P  P P++ 
Sbjct: 314 PSRAPTAAPPPPPPSRPSVA--VPPPPPNRMYPPPPPALP-----SSAPSGPPPPPPSVL 366

Query: 400 ------PATPPATPPAASPSALKGVSQD--------------LLERIRAKEAQKQLAQMT 439
                 P  PP  PP   P    G+  D              LL++IR     K++ Q +
Sbjct: 367 GVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNS 426

Query: 440 R---CPEQEQRLQRLERLPELARV 460
           R   C  ++  L ++ +  +L  V
Sbjct: 427 RPVSCSGRDALLDQIRQGIQLKSV 450



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 30/99 (30%), Positives = 35/99 (35%), Gaps = 12/99 (12%)

Query: 12  RRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGR-DQARPPARRRL 70
           R+ P PP   PP      P P  P    P      +R R  PP  P R   A PP     
Sbjct: 274 RQAPPPP---PPSRGGPPPPPPPPHNSGPPPPP--ARGRGAPPPPPSRAPTAAPPPPPPS 328

Query: 71  RLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPP 109
           R SV      + P  P     P P   +  S P+   PP
Sbjct: 329 RPSV------AVPPPPPNRMYPPPPPALPSSAPSGPPPP 361


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 108/428 (25%), Positives = 150/428 (35%), Gaps = 66/428 (15%)

Query: 14  RPGPPRIAPPKLACRTPSPARPAL----RAPASATSGSRKRARPPAAPGRDQARPPARRR 69
           R GP R A    + R P+   PA     RAP +  +     + P  A G  +  P  ++ 
Sbjct: 76  RAGPTRSAGT--SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133

Query: 70  LRLSVDE-VSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELA---- 124
           LR+S +E V+     EAP   A  S G +   S P  G P    + + +   +E+     
Sbjct: 134 LRISAEETVARGKATEAPKRSAL-SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192

Query: 125 --SCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPGLP 182
             S   R    G R     AS     E  +P A  RP    G + PA +   + A P   
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATP--- 248

Query: 183 GLVLPYKYQVLAEMFRSMDTIVGM----LHNRSETPTFAKVQRGVQDMMRRRFEECNVGQ 238
                     L+   RS  +  G      H     P   +  R  Q    R+     +G 
Sbjct: 249 ----------LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 239 IKT---VYPASYRFRQERSVPTFKDGTRRSDY--QLTIEPLLEQEADGAAPQLTA--SRL 291
           + +     P+     Q ++ PT       S    QL     L   +  A P L    S  
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358

Query: 292 LQRRQIFSQKLVEHVKEHHKAFLAS--LSPAMVVPEDQLTRWHPRFNVDEVPDIEPA-AL 348
                  +  L     +   +FL S  LSP    P                P   PA AL
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----------------PQAPPALAL 402

Query: 349 P--QPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPAT 406
           P  Q P +   +     LA      SP+   AL+ + L  A  S P SP    P +PPA+
Sbjct: 403 PPLQAPPSPPASPPLSPLATP----SPQAPNALA-VHLLQAPFSPPPSPPVQAPFSPPAS 457

Query: 407 PPAASPSA 414
           PP  SPSA
Sbjct: 458 PP-VSPSA 464



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 25/193 (12%)

Query: 17  PPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQ--------ARPPARR 68
           PP  APP    + P  A PAL  P      S   + P  AP            A PP + 
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562

Query: 69  RLRLSVDEVSSPSTP------EAPDIPACPSPGQKI---KKSTPAAGQPPHLTSAQDQDT 119
              L+   +  P +P      +AP  P  P P   +   + +   A  PP   S     T
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622

Query: 120 IS--ELASCLQRARELGARVRALKASAQ-DAGESCTPEAEGRPEEPCG-EKAPAYQRFHA 175
           +S  +LA     A      +R   +  +  A  S  P+AE     P    + PA      
Sbjct: 623 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA----PP 678

Query: 176 LAQPGLPGLVLPY 188
           LA  G PG  LP+
Sbjct: 679 LAFRGAPGAPLPW 691



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 341 PDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALRSAAPSSPG----SPR 396
           P + P+A P P A   L      LA+      P +     Q AL S   S PG    SP 
Sbjct: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPS 547

Query: 397 PALPATPPATPPAASPSAL 415
            +LP +P ATPP  +P  L
Sbjct: 548 ASLPMSPLATPPPQAPPVL 566



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 45/166 (27%), Positives = 59/166 (35%), Gaps = 11/166 (6%)

Query: 15  PGPPRIAPPKLACRTPSPARP------ALRAPASATSGSRKRA--RPPAAPG-RDQARPP 65
           P PP  +PP     TPSP  P       L+AP S       +A   PPA+P     A PP
Sbjct: 409 PSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467

Query: 66  ARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTISELAS 125
           ++    L+   +  P +P A   P  PS     +   P A  P  L     Q   +    
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526

Query: 126 CLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQ 171
            LQ      A        +  A    +P A   P+ P    AP  Q
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 15/105 (14%)

Query: 314 LASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISP 373
           L +L P  V P        PR   D  P + P +   P AT   + A +  A      +P
Sbjct: 277 LQALRPPQVTP--------PR--KDAAPALGPLS-SSPLATPSPSAALQSQAPPTLPATP 325

Query: 374 RMEKALSQLALR-SAAPSSPGSPRPALPA--TPPATPPAASPSAL 415
                  QLA     AP SP +P P+L    +PPATPP+ + ++L
Sbjct: 326 HSSSLTCQLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQATTSL 369



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 13/111 (11%)

Query: 11  ARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRL 70
           ARRRP        + A R+ S +   L +PA +   +R   R PA P   Q +P   + L
Sbjct: 224 ARRRPSAGG-GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQAL 280

Query: 71  RLSVDEVSSPSTPEAPDIP-------ACPSPGQKIK-KSTPAAGQPPHLTS 113
           R    +V+ P    AP +        A PSP   ++ ++ P     PH +S
Sbjct: 281 R--PPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 9/82 (10%)

Query: 341 PDIEPAALPQPPATEKLTT-------AQEVLARARNLISPRMEKALSQLALR-SAAPSSP 392
           P + P A P P A   L         +       +   SP     +S  A   S AP S 
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474

Query: 393 GSPRPALPATPPATPPAASPSA 414
            +P   +P +PPA+PP  SPSA
Sbjct: 475 AAPPLQVPPSPPASPP-MSPSA 495



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 9/98 (9%)

Query: 21  APPKLACRTPSP-ARPALRAPASATSGSRKRARPPAAPGRDQARPPARRRLRLSVDEVSS 79
           +PP     TP P A PAL  P      S   A PP +P    A P  +    L+V  + +
Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAPPS-PPASPPLSP---LATPSPQAPNALAVHLLQA 438

Query: 80  P-STPEAPDIPACPSPGQK---IKKSTPAAGQPPHLTS 113
           P S P +P + A  SP         +TP +  PP L +
Sbjct: 439 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.130    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,563,252
Number of Sequences: 37866
Number of extensions: 1351873
Number of successful extensions: 19170
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 923
Number of HSP's that attempted gapping in prelim test: 13877
Number of HSP's gapped (non-prelim): 5651
length of query: 546
length of database: 18,247,518
effective HSP length: 107
effective length of query: 439
effective length of database: 14,195,856
effective search space: 6231980784
effective search space used: 6231980784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.