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Search of human proteins with 188219593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
(375 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 793 0.0
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 783 0.0
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 608 e-174
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 598 e-171
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 117 1e-26
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 116 3e-26
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 114 1e-25
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 114 2e-25
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 114 2e-25
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 114 2e-25
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 104 1e-22
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 104 1e-22
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 103 3e-22
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 103 3e-22
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 103 3e-22
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 103 3e-22
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 101 1e-21
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 101 1e-21
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 100 2e-21
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 100 2e-21
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 98 1e-20
gi|38201714 ELAV-like 1 [Homo sapiens] 97 2e-20
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 85 1e-16
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 85 1e-16
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 85 1e-16
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 81 1e-15
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 81 1e-15
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 79 5e-15
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 79 5e-15
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 77 2e-14
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 793 bits (2048), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
Sbjct: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS
Sbjct: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
Query: 181 TYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGY 240
TYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGY
Sbjct: 181 TYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGY 240
Query: 241 SFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWGQ 300
SFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWGQ
Sbjct: 241 SFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWGQ 300
Query: 301 WYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGVQPPQGQNGSML 360
WYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGVQPPQGQNGSML
Sbjct: 301 WYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGVQPPQGQNGSML 360
Query: 361 PNQPSGYRVAGYETQ 375
PNQPSGYRVAGYETQ
Sbjct: 361 PNQPSGYRVAGYETQ 375
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 783 bits (2021), Expect = 0.0
Identities = 374/386 (96%), Positives = 375/386 (97%), Gaps = 11/386 (2%)
Query: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
Sbjct: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSN-----------HFHVFVGDLSPEITTE 109
AALAAMNGRKIMGKEVKVNWATTPSSQKKDTS+ HFHVFVGDLSPEITTE
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
Query: 110 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 169
DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN
Sbjct: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
Query: 170 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 229
WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI
Sbjct: 181 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 240
Query: 230 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 289
MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI
Sbjct: 241 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 300
Query: 290 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 349
GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV
Sbjct: 301 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 360
Query: 350 QPPQGQNGSMLPNQPSGYRVAGYETQ 375
QPPQGQNGSMLPNQPSGYRVAGYETQ
Sbjct: 361 QPPQGQNGSMLPNQPSGYRVAGYETQ 386
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 608 bits (1569), Expect = e-174
Identities = 300/378 (79%), Positives = 327/378 (86%), Gaps = 10/378 (2%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAA 61
+D P+TLYVGNLSRDVTE LILQLFSQIGPCK+CKMI + NDPYCFVEF+EHR AAA
Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAA 63
Query: 62 ALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRI 121
ALAAMNGRKI+GKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIK+AFAPFG+I
Sbjct: 64 ALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKI 123
Query: 122 SDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKST 181
SDARVVKDMATGKSKGYGFVSF+NK DAENAI MGGQWLGGRQIRTNWATRKPPAPKST
Sbjct: 124 SDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKST 183
Query: 182 YESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYS 241
E+NTKQL +++VVNQSSP NCTVYCGG+ SGLT+QLMRQTFSPFGQIMEIRVFP+KGYS
Sbjct: 184 QENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYS 243
Query: 242 FVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWGQW 301
FVRF++HESAAHAIVSVNGTTIEGHVVKCYWGKE+ DM Q Q+ Y Q +GQW Q
Sbjct: 244 FVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQ---QVDYSQ-WGQWSQV 299
Query: 302 YGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPNYGVQPPQGQNGSML 360
YGN QQ GQYM NGWQVP YG+YGQ WNQQGF QS SA WMG +G QPPQGQ +
Sbjct: 300 YGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-GFGAQPPQGQAPPPV 358
Query: 361 ---PNQPSGYRVAGYETQ 375
PNQ +GY +A Y+TQ
Sbjct: 359 IPPPNQ-AGYGMASYQTQ 375
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 598 bits (1542), Expect = e-171
Identities = 300/395 (75%), Positives = 327/395 (82%), Gaps = 27/395 (6%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDT-----------------AG 44
+D P+TLYVGNLSRDVTE LILQLFSQIGPCK+CKMI +
Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTS 63
Query: 45 NDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP 104
NDPYCFVEF+EHR AAAALAAMNGRKI+GKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP
Sbjct: 64 NDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP 123
Query: 105 EITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGR 164
EITTEDIK+AFAPFG+ISDARVVKDMATGKSKGYGFVSF+NK DAENAI MGGQWLGGR
Sbjct: 124 EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGR 183
Query: 165 QIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFS 224
QIRTNWATRKPPAPKST E+NTKQL +++VVNQSSP NCTVYCGG+ SGLT+QLMRQTFS
Sbjct: 184 QIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFS 243
Query: 225 PFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQ 284
PFGQIMEIRVFP+KGYSFVRF++HESAAHAIVSVNGTTIEGHVVKCYWGKE+ DM Q
Sbjct: 244 PFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQ 303
Query: 285 QQNQIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWM 343
Q+ Y Q +GQW Q YGN QQ GQYM NGWQVP YG+YGQ WNQQGF QS SA WM
Sbjct: 304 ---QVDYSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWM 359
Query: 344 GPNYGVQPPQGQNGSML---PNQPSGYRVAGYETQ 375
G +G QPPQGQ + PNQ +GY +A Y+TQ
Sbjct: 360 G-GFGAQPPQGQAPPPVIPPPNQ-AGYGMASYQTQ 392
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 117 bits (294), Expect = 1e-26
Identities = 73/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
++V NL + + + S G +C ++ D G+ Y FV F H A A+ MNG
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSNHF----HVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+ G++V V + ++ + +V++ + ++ E +K F FG
Sbjct: 161 MLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+V+ D +GKSKG+GFVSF DA+ A+ +M G+ L G+QI A +K ++ +
Sbjct: 221 KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER-QTELKR 278
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
+Q+ D + +Y + G+ ++ +R+ FSPFG I +V + KG+
Sbjct: 279 TFEQMKQDRITRYQV---VNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGF 335
Query: 241 SFVRFNSHESAAHAIVSVNGTTI 263
FV F+S E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 114 bits (285), Expect = 1e-25
Identities = 81/266 (30%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T+G+ Y +V F + A AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
MN I GK V++ W+ PS +K N +FV +L I + + + FG I
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGN---IFVKNLDKSINNKALYDTVSAFGNILSC 128
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
VV D SKGYGFV F AE AI++M G L GR++ ++S
Sbjct: 129 NVVCD--ENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFV-----------GQFKS 175
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
++ + + + VY + ++ ++ F FG + ++V D KG
Sbjct: 176 RKER---EAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG 232
Query: 240 YSFVRFNSHESAAHAIVSVNGTTIEG 265
+ FV F HE A A+ +NG + G
Sbjct: 233 FGFVSFERHEDAQKAVDEMNGKELNG 258
Score = 90.9 bits (224), Expect = 2e-18
Identities = 68/244 (27%), Positives = 113/244 (46%), Gaps = 23/244 (9%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N D+ + + LF + GP + K++ D +G + FV F H A A+ MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 68 GRKIMGKEVKVNWAT-----------TPSSQKKDTSNHFHV---FVGDLSPEITTEDIKA 113
G+++ GK++ V A T K+D + V +V +L I E ++
Sbjct: 253 GKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRK 312
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
AF+PFG I+ A+V+ M G+SKG+GFV F + +A A+ +M G+ + + + A R
Sbjct: 313 AFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR 370
Query: 174 KPPAPK-STYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEI 232
K T E + S V NQ +P + G + + + + P QI +
Sbjct: 371 KEERQAYLTNEYMQRMASVRAVPNQRAPPS-----GYFMTAVPQTQNHAAYYPPSQIARL 425
Query: 233 RVFP 236
R P
Sbjct: 426 RPSP 429
Score = 86.3 bits (212), Expect = 4e-17
Identities = 54/189 (28%), Positives = 87/189 (46%), Gaps = 27/189 (14%)
Query: 84 PSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSF 143
PS+ T++ ++VGDL P++T + F+P G I R+ +D+ T S Y +V+F
Sbjct: 3 PSTPSYPTAS---LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNF 59
Query: 144 FNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNC 203
+ DAE+A+ M + G+ +R W+ R P KS +
Sbjct: 60 QHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGN------------------- 100
Query: 204 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVN 259
++ + + + + T S FG I+ V D KGY FV F +HE+A AI +N
Sbjct: 101 -IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMN 159
Query: 260 GTTIEGHVV 268
G + G V
Sbjct: 160 GMLLNGRKV 168
Score = 49.3 bits (116), Expect = 6e-06
Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 8/88 (9%)
Query: 195 VNQSSPS--NCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFN 246
+N S+PS ++Y G + +TE ++ + FSP G I+ IR+ D Y++V F
Sbjct: 1 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 60
Query: 247 SHESAAHAIVSVNGTTIEGHVVKCYWGK 274
+ A HA+ ++N I+G V+ W +
Sbjct: 61 HTKDAEHALDTMNFDVIKGKPVRIMWSQ 88
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 116 bits (291), Expect = 3e-26
Identities = 72/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+ ++V V + ++ + +V++ + ++ E +K F FG
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+V+ D +GKSKG+GFVSF DA+ A+ +M G+ L G+QI A +K ++ +
Sbjct: 221 KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER-QTELKR 278
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
+Q+ D + +Y + G+ ++ +R+ FSPFG I +V + KG+
Sbjct: 279 KFEQMKQDRITRY---QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGF 335
Query: 241 SFVRFNSHESAAHAIVSVNGTTI 263
FV F+S E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 110 bits (276), Expect = 2e-24
Identities = 79/266 (29%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
MN I GK V++ W+ PS +K N +F+ +L I + + F+ FG I
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGN---IFIKNLDKSIDNKALYDTFSAFGNILSC 128
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+VV D SKGYGFV F + AE AI++M G L R++ ++S
Sbjct: 129 KVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV-----------GRFKS 175
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
++ + + + VY + ++ ++ F FG + ++V D KG
Sbjct: 176 RKER---EAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG 232
Query: 240 YSFVRFNSHESAAHAIVSVNGTTIEG 265
+ FV F HE A A+ +NG + G
Sbjct: 233 FGFVSFERHEDAQKAVDEMNGKELNG 258
Score = 86.7 bits (213), Expect = 3e-17
Identities = 61/248 (24%), Positives = 115/248 (46%), Gaps = 25/248 (10%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N D+ + + LF + GP + K++ D +G + FV F H A A+ MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
G+++ GK++ V A ++ + F +++V +L I E ++
Sbjct: 253 GKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRK 312
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
F+PFG I+ A+V+ M G+SKG+GFV F + +A A+ +M G+ + + + A R
Sbjct: 313 EFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR 370
Query: 174 KPPAPKSTYESNTKQLSY-----DEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQ 228
K ++++ + V+N P+ + Y + + + R + P Q
Sbjct: 371 KEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGY---FMAAIPQTQNRAAYYPPSQ 427
Query: 229 IMEIRVFP 236
I ++R P
Sbjct: 428 IAQLRPSP 435
Score = 86.3 bits (212), Expect = 4e-17
Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 24/176 (13%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
++VGDL P++T + F+P G I RV +DM T +S GY +V+F DAE A+ M
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
+ G+ +R W+ R P KS + ++ + +
Sbjct: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFIKNLDKSIDN 112
Query: 217 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
+ + TFS FG I+ +V D KGY FV F + E+A AI +NG + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168
Score = 47.4 bits (111), Expect = 2e-05
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 8/88 (9%)
Query: 195 VNQSSPSN--CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFN 246
+N S+PS ++Y G + +TE ++ + FSP G I+ IRV D GY++V F
Sbjct: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
Query: 247 SHESAAHAIVSVNGTTIEGHVVKCYWGK 274
A A+ ++N I+G V+ W +
Sbjct: 61 QPADAERALDTMNFDVIKGKPVRIMWSQ 88
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 114 bits (285), Expect = 1e-25
Identities = 80/269 (29%), Positives = 134/269 (49%), Gaps = 27/269 (10%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTE L+ + FS +GP + ++ D T + Y +V F + A AL
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDAR 125
MN I GK +++ W+ + ++ S +VF+ +L I + + F+ FG+I ++
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRR--SGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
Query: 126 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESN 185
V+ D SKGY FV F N+ A+ AI++M G+ L G ++ +
Sbjct: 129 VMSD--DQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKV---------------FVGR 171
Query: 186 TKQLSYDEVVNQSSPSNCT-VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
K E +S S T VY + ++ ++ FS +G+ + ++V D KG
Sbjct: 172 FKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKG 231
Query: 240 YSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
+ FV F+SHE+A A+ +NG I G ++
Sbjct: 232 FGFVSFDSHEAAKKAVEEMNGRDINGQLI 260
Score = 101 bits (252), Expect = 1e-21
Identities = 66/260 (25%), Positives = 127/260 (48%), Gaps = 13/260 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + + FS G + K++ D G+ Y FV F A A+ MNG
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
Query: 69 RKIMGKEVKV----NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+ + G +V V N + + S +V++ + ++ E +K F+ +G+
Sbjct: 160 KLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSV 219
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+V+ D ++GKSKG+GFVSF + A+ A+++M G+ + G+ I A +K ++ +
Sbjct: 220 KVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVER-QAELKQ 277
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
+QL + + +Y + + ++ +R FS FG I ++V + KG+
Sbjct: 278 MFEQLKRERI---RGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGF 334
Query: 241 SFVRFNSHESAAHAIVSVNG 260
+ F+S E A A+ +NG
Sbjct: 335 GLICFSSPEDATKAMTEMNG 354
Score = 73.6 bits (179), Expect = 3e-13
Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N D+ + + +FS+ G + K++ D++G + FV F H A A+ MN
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMN 251
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKA 113
GR I G+ + V A ++ + F +++ +L I E ++
Sbjct: 252 GRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRN 311
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
F+ FG IS +V+++ G+SKG+G + F + DA A+ +M G+ LG + + A R
Sbjct: 312 EFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 204 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 257
++Y G + + +TE L+ + FS G ++ IR+ D+ GY++V F A A+ +
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 258 VNGTTIEGHVVKCYWGK 274
+N I+G ++ W +
Sbjct: 71 MNFDIIKGKSIRLMWSQ 87
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 114 bits (284), Expect = 2e-25
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 13/263 (4%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+ ++V V + ++ + +V++ + E+ E +K F+ FG+
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K ++ +
Sbjct: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
+QL + + S +Y + + ++ +R+ FSPFG I +V + KG+
Sbjct: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
Query: 241 SFVRFNSHESAAHAIVSVNGTTI 263
FV F+S E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 112 bits (280), Expect = 5e-25
Identities = 80/269 (29%), Positives = 127/269 (47%), Gaps = 27/269 (10%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNILSC 128
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+VV D SKGY FV F + A+ AI++M G L R++ + R + E
Sbjct: 129 KVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREAEL 183
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
K + VY + ++ +++ FS FG+ + ++V D KG
Sbjct: 184 GAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 232
Query: 240 YSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
+ FV + HE A A+ +NG I G ++
Sbjct: 233 FGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.7 bits (208), Expect = 1e-16
Identities = 51/181 (28%), Positives = 92/181 (50%), Gaps = 17/181 (9%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 174 K 174
K
Sbjct: 371 K 371
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 198 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 251
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 252 AHAIVSVNGTTIEGHVVKCYWGK 274
A+ ++N I+G ++ W +
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 114 bits (284), Expect = 2e-25
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 13/263 (4%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+ ++V V + ++ + +V++ + E+ E +K F+ FG+
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K ++ +
Sbjct: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
+QL + + S +Y + + ++ +R+ FSPFG I +V + KG+
Sbjct: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
Query: 241 SFVRFNSHESAAHAIVSVNGTTI 263
FV F+S E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 112 bits (280), Expect = 5e-25
Identities = 80/269 (29%), Positives = 127/269 (47%), Gaps = 27/269 (10%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNILSC 128
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+VV D SKGY FV F + A+ AI++M G L R++ + R + E
Sbjct: 129 KVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREAEL 183
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
K + VY + ++ +++ FS FG+ + ++V D KG
Sbjct: 184 GAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 232
Query: 240 YSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
+ FV + HE A A+ +NG I G ++
Sbjct: 233 FGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.7 bits (208), Expect = 1e-16
Identities = 51/181 (28%), Positives = 92/181 (50%), Gaps = 17/181 (9%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 174 K 174
K
Sbjct: 371 K 371
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 198 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 251
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 252 AHAIVSVNGTTIEGHVVKCYWGK 274
A+ ++N I+G ++ W +
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 114 bits (284), Expect = 2e-25
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 13/263 (4%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+ ++V V + ++ + +V++ + E+ E +K F+ FG+
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K ++ +
Sbjct: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
+QL + + S +Y + + ++ +R+ FSPFG I +V + KG+
Sbjct: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
Query: 241 SFVRFNSHESAAHAIVSVNGTTI 263
FV F+S E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 112 bits (280), Expect = 5e-25
Identities = 80/269 (29%), Positives = 127/269 (47%), Gaps = 27/269 (10%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNILSC 128
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+VV D SKGY FV F + A+ AI++M G L R++ + R + E
Sbjct: 129 KVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREAEL 183
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
K + VY + ++ +++ FS FG+ + ++V D KG
Sbjct: 184 GAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 232
Query: 240 YSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
+ FV + HE A A+ +NG I G ++
Sbjct: 233 FGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.7 bits (208), Expect = 1e-16
Identities = 51/181 (28%), Positives = 92/181 (50%), Gaps = 17/181 (9%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 174 K 174
K
Sbjct: 371 K 371
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 198 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 251
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 252 AHAIVSVNGTTIEGHVVKCYWGK 274
A+ ++N I+G ++ W +
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 104 bits (260), Expect = 1e-22
Identities = 78/291 (26%), Positives = 138/291 (47%), Gaps = 35/291 (12%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D A Y ++ F + A AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
MN + G+ +++ W+ P +K N +F+ +L I + + F+ FG I
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGN---IFIKNLEDSIDNKALYDTFSTFGNILSC 128
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRT-NWATRKPPAPKSTYE 183
+V D S+G+GFV F A+ AI M G L R++ ++ +R+ + E
Sbjct: 129 KVACD--EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRR----EREAE 182
Query: 184 SNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKG---- 239
+ L + + ++ P + + EQ ++ FS FG+++ ++V D
Sbjct: 183 LGARALEFTNIYVKNLPVD-----------VDEQGLQDLFSQFGKMLSVKVMRDNSGHSR 231
Query: 240 -YSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 289
+ FV F HE A A+V +NG + G ++ Y G+ V++QN++
Sbjct: 232 CFGFVNFEKHEEAQKAVVHMNGKEVSGRLL--YAGRAQ----KRVERQNEL 276
Score = 95.1 bits (235), Expect = 9e-20
Identities = 62/263 (23%), Positives = 125/263 (47%), Gaps = 13/263 (4%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + FS G +CK+ D G+ + FV F H A A+ MNG
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTS----NHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+ ++V V + ++ + +++V +L ++ + ++ F+ FG++
Sbjct: 161 MLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSV 220
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
+V++D +G S+ +GFV+F +A+ A+ M G+ + GR + A +K ++ +
Sbjct: 221 KVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRA-QKRVERQNELKR 278
Query: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
+Q+ D + +Y + + + +R+ FSP+G I +V + KG+
Sbjct: 279 RFEQMKQDRLRRY---QGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGF 335
Query: 241 SFVRFNSHESAAHAIVSVNGTTI 263
FV F+S E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 82.4 bits (202), Expect = 6e-16
Identities = 52/181 (28%), Positives = 92/181 (50%), Gaps = 17/181 (9%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+YV NL DV E + LFSQ G + K++ D +G+ + FV F +H A A+ MN
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
G+++ G+ + A ++ + F +++V +L I + ++
Sbjct: 253 GKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRK 312
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
F+P+G I+ A+V+ + G SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQR 370
Query: 174 K 174
K
Sbjct: 371 K 371
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 104 bits (260), Expect = 1e-22
Identities = 66/264 (25%), Positives = 124/264 (46%), Gaps = 14/264 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + LFS G +CK++ D G+ Y +V F A A+ MNG
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
Query: 69 RKIMGKEVKVNWATTPSS-----QKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISD 123
++ ++V V P + +D + +VFV ++ +I E +K F +G
Sbjct: 168 VRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTES 227
Query: 124 ARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYE 183
+V++D A+GKSKG+GFV + A+ A+ + G+ + G+ + A +K
Sbjct: 228 VKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKK----IERLA 282
Query: 184 SNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KG 239
++ + +S P +Y + + ++ +++ FS FG I +V + KG
Sbjct: 283 ELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKG 342
Query: 240 YSFVRFNSHESAAHAIVSVNGTTI 263
+ V F+S E A A+ +NG +
Sbjct: 343 FGVVCFSSFEEATKAVDEMNGRIV 366
Score = 97.4 bits (241), Expect = 2e-20
Identities = 74/267 (27%), Positives = 122/267 (45%), Gaps = 24/267 (8%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAM 66
LYVG+L DVTE ++ + F GP + ++ D P Y +V F A AL M
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 67 NGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARV 126
N I GK ++ W+ +K S ++F+ +L I + F+ FG I +V
Sbjct: 80 NFDLINGKPFRLMWSQPDDRLRK--SGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
Query: 127 VKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNT 186
V D SKGY +V F + A AI M G L RQ+ K P ++
Sbjct: 138 VCD--DNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVG--RFKFPEERAA----- 188
Query: 187 KQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KGYS 241
EV + + V+ + + ++ +++ F +G ++V D KG+
Sbjct: 189 ------EVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
Query: 242 FVRFNSHESAAHAIVSVNGTTIEGHVV 268
FVR+ +HE+A A++ ++G +I+G V+
Sbjct: 243 FVRYETHEAAQKAVLDLHGKSIDGKVL 269
Score = 74.7 bits (182), Expect = 1e-13
Identities = 46/173 (26%), Positives = 85/173 (49%), Gaps = 17/173 (9%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
++V N+ D+ + + +LF + GP ++ K+I D +G + FV + H A A+ ++
Sbjct: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKA 113
G+ I GK + V A + + F +++ +L I E +K
Sbjct: 261 GKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKE 320
Query: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI 166
F+ FG IS A+V+ M G+ KG+G V F + +A A+ +M G+ +G + +
Sbjct: 321 EFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
Score = 32.7 bits (73), Expect = 0.55
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 205 VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSV 258
+Y G + +TE ++ + F P G + R+ D GY +V F A A+ ++
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 259 NGTTIEGHVVKCYWGK 274
N I G + W +
Sbjct: 80 NFDLINGKPFRLMWSQ 95
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 103 bits (256), Expect = 3e-22
Identities = 78/318 (24%), Positives = 145/318 (45%), Gaps = 55/318 (17%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 45 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 104
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 105 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 160
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ KS
Sbjct: 161 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 220
Query: 181 T-------YES-----------NTKQLSYDEVVNQS------SP---------------- 200
+ Y+S ++ D ++N + SP
Sbjct: 221 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 280
Query: 201 ---SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESA 251
+ ++ ++ E ++ Q F PFG + ++V D KG+ FV +++ A
Sbjct: 281 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 340
Query: 252 AHAIVSVNGTTIEGHVVK 269
A AI S+NG + V++
Sbjct: 341 AMAIASLNGYRLGDRVLQ 358
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 91 TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE 150
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 282 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 341
Query: 151 NAIQQMGGQWLGGRQIRTNWATRK 174
AI + G LG R ++ ++ T K
Sbjct: 342 MAIASLNGYRLGDRVLQVSFKTNK 365
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 67 NGRKIMGKEVKVNWAT 82
NG ++ + ++V++ T
Sbjct: 348 NGYRLGDRVLQVSFKT 363
Score = 32.0 bits (71), Expect = 0.93
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 60 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 119
Query: 268 VKCYWGK 274
+K + +
Sbjct: 120 IKVSYAR 126
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 103 bits (256), Expect = 3e-22
Identities = 78/318 (24%), Positives = 145/318 (45%), Gaps = 55/318 (17%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ KS
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 181 T-------YES-----------NTKQLSYDEVVNQS------SP---------------- 200
+ Y+S ++ D ++N + SP
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 277
Query: 201 ---SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESA 251
+ ++ ++ E ++ Q F PFG + ++V D KG+ FV +++ A
Sbjct: 278 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 337
Query: 252 AHAIVSVNGTTIEGHVVK 269
A AI S+NG + V++
Sbjct: 338 AMAIASLNGYRLGDRVLQ 355
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 91 TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE 150
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 279 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 338
Query: 151 NAIQQMGGQWLGGRQIRTNWATRK 174
AI + G LG R ++ ++ T K
Sbjct: 339 MAIASLNGYRLGDRVLQVSFKTNK 362
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 67 NGRKIMGKEVKVNWAT 82
NG ++ + ++V++ T
Sbjct: 345 NGYRLGDRVLQVSFKT 360
Score = 32.0 bits (71), Expect = 0.93
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
Query: 268 VKCYWGK 274
+K + +
Sbjct: 117 IKVSYAR 123
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 103 bits (256), Expect = 3e-22
Identities = 78/318 (24%), Positives = 145/318 (45%), Gaps = 55/318 (17%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 174
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ KS
Sbjct: 175 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 234
Query: 181 T-------YES-----------NTKQLSYDEVVNQS------SP---------------- 200
+ Y+S ++ D ++N + SP
Sbjct: 235 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 294
Query: 201 ---SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESA 251
+ ++ ++ E ++ Q F PFG + ++V D KG+ FV +++ A
Sbjct: 295 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 354
Query: 252 AHAIVSVNGTTIEGHVVK 269
A AI S+NG + V++
Sbjct: 355 AMAIASLNGYRLGDRVLQ 372
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 91 TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE 150
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
Query: 151 NAIQQMGGQWLGGRQIRTNWATRK 174
AI + G LG R ++ ++ T K
Sbjct: 356 MAIASLNGYRLGDRVLQVSFKTNK 379
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 67 NGRKIMGKEVKVNWAT 82
NG ++ + ++V++ T
Sbjct: 362 NGYRLGDRVLQVSFKT 377
Score = 32.0 bits (71), Expect = 0.93
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 74 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 133
Query: 268 VKCYWGK 274
+K + +
Sbjct: 134 IKVSYAR 140
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 103 bits (256), Expect = 3e-22
Identities = 78/318 (24%), Positives = 145/318 (45%), Gaps = 55/318 (17%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ KS
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 181 T-------YES-----------NTKQLSYDEVVNQS------SP---------------- 200
+ Y+S ++ D ++N + SP
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 277
Query: 201 ---SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESA 251
+ ++ ++ E ++ Q F PFG + ++V D KG+ FV +++ A
Sbjct: 278 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 337
Query: 252 AHAIVSVNGTTIEGHVVK 269
A AI S+NG + V++
Sbjct: 338 AMAIASLNGYRLGDRVLQ 355
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 91 TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE 150
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 279 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 338
Query: 151 NAIQQMGGQWLGGRQIRTNWATRK 174
AI + G LG R ++ ++ T K
Sbjct: 339 MAIASLNGYRLGDRVLQVSFKTNK 362
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 67 NGRKIMGKEVKVNWAT 82
NG ++ + ++V++ T
Sbjct: 345 NGYRLGDRVLQVSFKT 360
Score = 32.0 bits (71), Expect = 0.93
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
Query: 268 VKCYWGK 274
+K + +
Sbjct: 117 IKVSYAR 123
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 101 bits (252), Expect = 1e-21
Identities = 82/332 (24%), Positives = 146/332 (43%), Gaps = 69/332 (20%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ KS
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 181 T-------YES-----------NTKQLSYDEVVNQS-----------SPSNCTVYCGGVT 211
+ Y+S ++ D ++N + PS C +T
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPIT 277
Query: 212 -SGLT---------------------------EQLMRQTFSPFGQIMEIRVFPD------ 237
G+T E ++ Q F PFG + ++V D
Sbjct: 278 IDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKC 337
Query: 238 KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
KG+ FV +++ AA AI S+NG + V++
Sbjct: 338 KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 369
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 91 TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE 150
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 293 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 352
Query: 151 NAIQQMGGQWLGGRQIRTNWATRK 174
AI + G LG R ++ ++ T K
Sbjct: 353 MAIASLNGYRLGDRVLQVSFKTNK 376
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 67 NGRKIMGKEVKVNWAT 82
NG ++ + ++V++ T
Sbjct: 359 NGYRLGDRVLQVSFKT 374
Score = 32.0 bits (71), Expect = 0.93
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
Query: 268 VKCYWGK 274
+K + +
Sbjct: 117 IKVSYAR 123
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 101 bits (252), Expect = 1e-21
Identities = 77/321 (23%), Positives = 146/321 (45%), Gaps = 61/321 (19%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
++ L V L +++T+ + LF IG ++CK++ D T + Y FV + + + A
Sbjct: 35 EDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 94
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 95 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 150
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQ------------WLGGRQIRT 168
I +R++ D TG S+G GF+ F + +AE AI+ + GQ + +T
Sbjct: 151 IITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKT 210
Query: 169 NWA---------TRKPPAPKSTYESNTKQLSYDEVVNQS------SP------------- 200
N A R+ P P + ++ D ++N + SP
Sbjct: 211 NQAILSQLYQSPNRRYPGPLA---QQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGIN 267
Query: 201 ------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSH 248
+ ++ + E ++ Q F PFG + ++V D KG+ FV ++
Sbjct: 268 IPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNY 327
Query: 249 ESAAHAIVSVNGTTIEGHVVK 269
+ AA AI S+NG + V++
Sbjct: 328 DEAAMAIASLNGYRLGDRVLQ 348
Score = 81.6 bits (200), Expect = 1e-15
Identities = 67/256 (26%), Positives = 113/256 (44%), Gaps = 40/256 (15%)
Query: 79 NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGY 138
N ++P + ++ V L +T E++K+ F G I ++V+D TG+S GY
Sbjct: 23 NNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGY 82
Query: 139 GFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQS 198
GFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 83 GFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN------------- 126
Query: 199 SPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAA 252
+Y G+ +T++ + Q FS +G+I+ R+ D +G F+RF+ A
Sbjct: 127 ------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
Query: 253 HAIVSVNGTTIEGHVVKCYWGKETLDM---INPVQQQNQIGYPQPYGQWGQWYGN--AQQ 307
AI +NG G E + + NP Q+ NQ Q Y + Y AQQ
Sbjct: 181 EAIKGLNGQKPPG-------ATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQ 233
Query: 308 IGQYMPNGWQVPAYGM 323
++ + AYG+
Sbjct: 234 AQRFRLDNLLNMAYGV 249
Score = 57.8 bits (138), Expect = 2e-08
Identities = 27/78 (34%), Positives = 46/78 (58%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
+FV +L+P+ + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 157 GGQWLGGRQIRTNWATRK 174
G LG R ++ ++ T K
Sbjct: 338 NGYRLGDRVLQVSFKTNK 355
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NL+ D E+++ Q+F G N K+I D N + FV + AA A+A++
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 67 NGRKIMGKEVKVNWAT 82
NG ++ + ++V++ T
Sbjct: 338 NGYRLGDRVLQVSFKT 353
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 100 bits (250), Expect = 2e-21
Identities = 64/176 (36%), Positives = 96/176 (54%), Gaps = 6/176 (3%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E T+YVG L V+E L+ +LF Q GP N M D T + Y FVEF A
Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67
Query: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFG 119
A+ MN K+ GK ++VN A S+ K+ ++F+G+L PEI + + F+ FG
Sbjct: 68 DYAIKIMNMIKLYGKPIRVNKA---SAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFG 124
Query: 120 RISDA-RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 174
I ++++D TG SKGY F++F + ++ AI+ M GQ+L R I ++A +K
Sbjct: 125 VILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
Score = 70.9 bits (172), Expect = 2e-12
Identities = 53/187 (28%), Positives = 89/187 (47%), Gaps = 31/187 (16%)
Query: 81 ATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGF 140
A P S++ + V+VG L +++ + F G + + + KD TG+ +GYGF
Sbjct: 2 AAGPISERNQDAT---VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGF 58
Query: 141 VSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSP 200
V F ++ DA+ AI+ M L G+ IR N A+ N++
Sbjct: 59 VEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAH---------------------NKNLD 97
Query: 201 SNCTVYCGGVTSGLTEQLMRQTFSPFGQIME---IRVFPD----KGYSFVRFNSHESAAH 253
++ G + + E+L+ TFS FG I++ I PD KGY+F+ F S +++
Sbjct: 98 VGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDA 157
Query: 254 AIVSVNG 260
AI ++NG
Sbjct: 158 AIEAMNG 164
Score = 45.8 bits (107), Expect = 6e-05
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIM---DTAGNDPYCFVEFHEHRHAAAALAA 65
+++GNL ++ E L+ FS G IM DT + Y F+ F + AA+ A
Sbjct: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSNHFH 96
MNG+ + + + V++A KKD+ H
Sbjct: 162 MNGQYLCNRPITVSYAF-----KKDSKGERH 187
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 100 bits (249), Expect = 2e-21
Identities = 81/319 (25%), Positives = 144/319 (45%), Gaps = 56/319 (17%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + A
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG K+ K +KV++A S+ +D + ++V L ++ ++++ F+ +GR
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDAN----LYVSGLPKTMSQKEMEQLFSQYGR 150
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ K+
Sbjct: 151 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKT 210
Query: 181 -------TYESN-----------TKQLSYDEVVNQS------SPSNCTVYCGGVTSGLT- 215
Y+S+ T++ D ++N + SP G GL+
Sbjct: 211 GQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSG 270
Query: 216 -------------------EQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHES 250
E ++ Q F PFG + ++V D KG+ FV +++
Sbjct: 271 GAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDE 330
Query: 251 AAHAIVSVNGTTIEGHVVK 269
AA AI S+NG + V++
Sbjct: 331 AAMAIASLNGYRLGERVLQ 349
Score = 60.1 bits (144), Expect = 3e-09
Identities = 29/78 (37%), Positives = 46/78 (58%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
+FV +LSPE + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 157 GGQWLGGRQIRTNWATRK 174
G LG R ++ ++ T K
Sbjct: 339 NGYRLGERVLQVSFKTSK 356
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS + E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 67 NGRKIMGKEVKVNWATT 83
NG ++ + ++V++ T+
Sbjct: 339 NGYRLGERVLQVSFKTS 355
Score = 30.0 bits (66), Expect = 3.5
Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T+ + F G I ++ DK GY FV ++ A AI ++NG ++
Sbjct: 50 MTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKT 109
Query: 268 VKCYWGK 274
+K + +
Sbjct: 110 IKVSYAR 116
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 97.8 bits (242), Expect = 1e-20
Identities = 81/326 (24%), Positives = 144/326 (44%), Gaps = 63/326 (19%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + A
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
A+ +NG K+ K +KV++A S+ +D + ++V L ++ ++++ F+ +GR
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDAN----LYVSGLPKTMSQKEMEQLFSQYGR 150
Query: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ K+
Sbjct: 151 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKT 210
Query: 181 -------TYESN-----------TKQLSYDEVVNQS-------------SPSNCTVYCGG 209
Y+S+ T++ D ++N + SP G
Sbjct: 211 GQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGL 270
Query: 210 VTSGLT--------------------EQLMRQTFSPFGQIMEIRVFPD------KGYSFV 243
GL+ E ++ Q F PFG + ++V D KG+ FV
Sbjct: 271 AGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFV 330
Query: 244 RFNSHESAAHAIVSVNGTTIEGHVVK 269
+++ AA AI S+NG + V++
Sbjct: 331 TMTNYDEAAMAIASLNGYRLGERVLQ 356
Score = 60.1 bits (144), Expect = 3e-09
Identities = 29/78 (37%), Positives = 46/78 (58%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
+FV +LSPE + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 157 GGQWLGGRQIRTNWATRK 174
G LG R ++ ++ T K
Sbjct: 346 NGYRLGERVLQVSFKTSK 363
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS + E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 67 NGRKIMGKEVKVNWATT 83
NG ++ + ++V++ T+
Sbjct: 346 NGYRLGERVLQVSFKTS 362
Score = 30.0 bits (66), Expect = 3.5
Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T+ + F G I ++ DK GY FV ++ A AI ++NG ++
Sbjct: 50 MTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKT 109
Query: 268 VKCYWGK 274
+K + +
Sbjct: 110 IKVSYAR 116
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 97.1 bits (240), Expect = 2e-20
Identities = 82/292 (28%), Positives = 133/292 (45%), Gaps = 46/292 (15%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGND-PYCFVEFHEHRHAAAALAAM 66
L V L +++T+ + LFS IG ++ K+I D AG+ Y FV + + A A+ +
Sbjct: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
Query: 67 NGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARV 126
NG ++ K +KV++A S KD ++++ L +T +D++ F+ FGRI ++RV
Sbjct: 82 NGLRLQSKTIKVSYARPSSEVIKDA----NLYISGLPRTMTQKDVEDMFSRFGRIINSRV 137
Query: 127 VKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGG--RQIRTNWATRKPPAPKST--- 181
+ D TG S+G F+ F + +AE AI G G I +A P K+
Sbjct: 138 LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAA-NPNQNKNVALL 196
Query: 182 ---YESNTKQ------------------------LSYDEVVNQSSPSNCTVYCGGVTSGL 214
Y S ++ LS V +S C ++ +
Sbjct: 197 SQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWC-IFIYNLGQDA 255
Query: 215 TEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNG 260
E ++ Q F PFG + ++V D KG+ FV ++E AA AI S+NG
Sbjct: 256 DEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
Score = 76.3 bits (186), Expect = 4e-14
Identities = 48/171 (28%), Positives = 84/171 (49%), Gaps = 28/171 (16%)
Query: 96 HVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQ 155
++ V L +T +++++ F+ G + A++++D G S GYGFV++ DAE AI
Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
Query: 156 MGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLT 215
+ G L + I+ ++A P S EV+ ++ +Y G+ +T
Sbjct: 81 LNGLRLQSKTIKVSYA-----RPSS------------EVIKDAN-----LYISGLPRTMT 118
Query: 216 EQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNG 260
++ + FS FG+I+ RV D +G +F+RF+ A AI S NG
Sbjct: 119 QKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
Score = 65.5 bits (158), Expect = 8e-11
Identities = 48/216 (22%), Positives = 89/216 (41%), Gaps = 50/216 (23%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LY+ L R +T+ + +FS+ G N ++++D T + F+ F + A A+ +
Sbjct: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
Query: 67 NGRKIMGKE--VKVNWATTPSSQKK----------------------------------- 89
NG K G + V +A P+ K
Sbjct: 168 NGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDH 227
Query: 90 -----------DTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGY 138
+ S+ + +F+ +L + + F PFG +++ +V++D T K KG+
Sbjct: 228 MSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
Query: 139 GFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 174
GFV+ N +A AI + G LG + ++ ++ T K
Sbjct: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
Score = 37.0 bits (84), Expect = 0.029
Identities = 18/73 (24%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
+T+ +R FS G++ ++ DK GY FV + + + A AI ++NG ++
Sbjct: 31 MTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKT 90
Query: 268 VKCYWGKETLDMI 280
+K + + + ++I
Sbjct: 91 IKVSYARPSSEVI 103
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 84.7 bits (208), Expect = 1e-16
Identities = 55/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 67 NGRKIMGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKAAFAPFG 119
N + G+ +KV A Q + + F+ ++V + +++ +DIK+ F FG
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 207
Query: 120 RISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPK 179
+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 208 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 266
Query: 180 ST 181
T
Sbjct: 267 LT 268
Score = 69.3 bits (168), Expect = 5e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 196
Query: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 197 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 255
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 203 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 256
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 86 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 145
Query: 257 SVNGTTIEGHVVK 269
+N + G +K
Sbjct: 146 QMNSVMLGGRNIK 158
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 84.7 bits (208), Expect = 1e-16
Identities = 55/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 67 NGRKIMGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKAAFAPFG 119
N + G+ +KV A Q + + F+ ++V + +++ +DIK+ F FG
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
Query: 120 RISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPK 179
+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 292
Query: 180 ST 181
T
Sbjct: 293 LT 294
Score = 69.3 bits (168), Expect = 5e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 222
Query: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 223 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 281
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 203 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 256
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 112 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 171
Query: 257 SVNGTTIEGHVVK 269
+N + G +K
Sbjct: 172 QMNSVMLGGRNIK 184
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 84.7 bits (208), Expect = 1e-16
Identities = 55/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 67 NGRKIMGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKAAFAPFG 119
N + G+ +KV A Q + + F+ ++V + +++ +DIK+ F FG
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 250
Query: 120 RISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPK 179
+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 251 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 309
Query: 180 ST 181
T
Sbjct: 310 LT 311
Score = 69.3 bits (168), Expect = 5e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 239
Query: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 240 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 298
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 203 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 256
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 129 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 188
Query: 257 SVNGTTIEGHVVK 269
+N + G +K
Sbjct: 189 QMNSVMLGGRNIK 201
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 81.3 bits (199), Expect = 1e-15
Identities = 61/198 (30%), Positives = 93/198 (46%), Gaps = 22/198 (11%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L +VTEA++ + FS GP + ++ D T + Y +V + + A AL
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+N I G+ V++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGN---VFIKNLGKTIDNKALYNIFSAFGNILSC 119
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI--------------RTNW 170
+V D KGYGFV F + AE AI M G +L R+I R W
Sbjct: 120 KVACD--EKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAW 177
Query: 171 ATRKPPAPKSTYESNTKQ 188
A + A +E +T +
Sbjct: 178 ARQSTSADVKDFEEDTDE 195
Score = 78.6 bits (192), Expect = 9e-15
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 24/168 (14%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
++VGDL PE+T + F+P G I R+ +D T +S GY +V++ DA+ A++ +
Sbjct: 4 LYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETL 63
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
+ GR +R W+ R P KS + V+ + +
Sbjct: 64 NFDVIKGRPVRIMWSQRDPSLRKSGVGN--------------------VFIKNLGKTIDN 103
Query: 217 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNG 260
+ + FS FG I+ +V D KGY FV F ESA AI +NG
Sbjct: 104 KALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNG 151
Score = 45.4 bits (106), Expect = 8e-05
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 204 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 257
++Y G + +TE ++ + FSP G I+ IR+ DK GY++V + A A+ +
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 258 VNGTTIEGHVVKCYWGK 274
+N I+G V+ W +
Sbjct: 63 LNFDVIKGRPVRIMWSQ 79
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 81.3 bits (199), Expect = 1e-15
Identities = 61/198 (30%), Positives = 93/198 (46%), Gaps = 22/198 (11%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L +VTEA++ + FS GP + ++ D T + Y +V + + A AL
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
+N I G+ V++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGN---VFIKNLGKTIDNKALYNIFSAFGNILSC 119
Query: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI--------------RTNW 170
+V D KGYGFV F + AE AI M G +L R+I R W
Sbjct: 120 KVACD--EKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAW 177
Query: 171 ATRKPPAPKSTYESNTKQ 188
A + A +E +T +
Sbjct: 178 ARQSTSADVKDFEEDTDE 195
Score = 78.6 bits (192), Expect = 9e-15
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 24/168 (14%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
++VGDL PE+T + F+P G I R+ +D T +S GY +V++ DA+ A++ +
Sbjct: 4 LYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETL 63
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
+ GR +R W+ R P KS + V+ + +
Sbjct: 64 NFDVIKGRPVRIMWSQRDPSLRKSGVGN--------------------VFIKNLGKTIDN 103
Query: 217 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNG 260
+ + FS FG I+ +V D KGY FV F ESA AI +NG
Sbjct: 104 KALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNG 151
Score = 45.4 bits (106), Expect = 8e-05
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 204 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 257
++Y G + +TE ++ + FSP G I+ IR+ DK GY++V + A A+ +
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 258 VNGTTIEGHVVKCYWGK 274
+N I+G V+ W +
Sbjct: 63 LNFDVIKGRPVRIMWSQ 79
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 79.3 bits (194), Expect = 5e-15
Identities = 48/190 (25%), Positives = 97/190 (51%), Gaps = 11/190 (5%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF +
Sbjct: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
Query: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111
A+ + G++++G + K A ++ +K ++ ++VG L IT + +
Sbjct: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
Query: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171
+ F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++
Sbjct: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326
Query: 172 TRKPPAPKST 181
T + A ++
Sbjct: 327 TERTDASSAS 336
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 17/179 (9%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
VF L+ I D++ F+ G++ D R++ D + +SKG +V F + AI
Sbjct: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
G + LG P +++ + + + + S +Y G + +TE
Sbjct: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
Query: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
++R F PFG+I I++ D KGY F+ F+ E A A+ +NG + G +K
Sbjct: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
Length = 530
Score = 79.3 bits (194), Expect = 5e-15
Identities = 48/190 (25%), Positives = 97/190 (51%), Gaps = 11/190 (5%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF +
Sbjct: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
Query: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111
A+ + G++++G + K A ++ +K ++ ++VG L IT + +
Sbjct: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
Query: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171
+ F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++
Sbjct: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326
Query: 172 TRKPPAPKST 181
T + A ++
Sbjct: 327 TERTDASSAS 336
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 17/179 (9%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
VF L+ I D++ F+ G++ D R++ D + +SKG +V F + AI
Sbjct: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
G + LG P +++ + + + + S +Y G + +TE
Sbjct: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
Query: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
++R F PFG+I I++ D KGY F+ F+ E A A+ +NG + G +K
Sbjct: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
Length = 405
Score = 77.4 bits (189), Expect = 2e-14
Identities = 48/183 (26%), Positives = 92/183 (50%), Gaps = 11/183 (6%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E +
Sbjct: 127 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 186
Query: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111
A+ + G++++G + K A ++ +K ++VG L IT + +
Sbjct: 187 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 245
Query: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171
+ F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R
Sbjct: 246 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 305
Query: 172 TRK 174
T +
Sbjct: 306 TER 308
Score = 67.8 bits (164), Expect = 2e-11
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI
Sbjct: 134 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 193
Query: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
G + LG P +++ + + + + + +Y G + +TE
Sbjct: 194 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 242
Query: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 270
++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++
Sbjct: 243 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 302
Query: 271 YWGKETLD 278
E LD
Sbjct: 303 GHVTERLD 310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,398,136
Number of Sequences: 37866
Number of extensions: 692098
Number of successful extensions: 3191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 256
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 1653
Number of HSP's gapped (non-prelim): 985
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.