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Search of human proteins with 188219591
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
(386 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 812 0.0
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 783 0.0
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 598 e-171
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 588 e-168
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 120 3e-27
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 119 6e-27
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 115 9e-26
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 115 9e-26
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 115 9e-26
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 109 5e-24
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 103 3e-22
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 99 5e-21
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 99 6e-21
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 99 6e-21
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 99 6e-21
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 99 6e-21
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 97 2e-20
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 97 2e-20
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 96 4e-20
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 94 2e-19
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 94 3e-19
gi|38201714 ELAV-like 1 [Homo sapiens] 93 5e-19
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 83 5e-16
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 83 5e-16
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 83 5e-16
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 80 4e-15
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 80 4e-15
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 79 9e-15
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 79 9e-15
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 76 6e-14
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 812 bits (2097), Expect = 0.0
Identities = 386/386 (100%), Positives = 386/386 (100%)
Query: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
Sbjct: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN
Sbjct: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
Query: 181 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 240
WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI
Sbjct: 181 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 240
Query: 241 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 300
MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI
Sbjct: 241 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 300
Query: 301 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 360
GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV
Sbjct: 301 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 360
Query: 361 QPPQGQNGSMLPNQPSGYRVAGYETQ 386
QPPQGQNGSMLPNQPSGYRVAGYETQ
Sbjct: 361 QPPQGQNGSMLPNQPSGYRVAGYETQ 386
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 783 bits (2021), Expect = 0.0
Identities = 374/386 (96%), Positives = 375/386 (97%), Gaps = 11/386 (2%)
Query: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
Sbjct: 1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA 60
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
AALAAMNGRKIMGKEVKVNWATTPSSQKKDTS+ HFHVFVGDLSPEITTE
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSN-----------HFHVFVGDLSPEITTE 109
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN
Sbjct: 110 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 169
Query: 181 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 240
WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI
Sbjct: 170 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI 229
Query: 241 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 300
MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI
Sbjct: 230 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 289
Query: 301 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 360
GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV
Sbjct: 290 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV 349
Query: 361 QPPQGQNGSMLPNQPSGYRVAGYETQ 386
QPPQGQNGSMLPNQPSGYRVAGYETQ
Sbjct: 350 QPPQGQNGSMLPNQPSGYRVAGYETQ 375
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 598 bits (1542), Expect = e-171
Identities = 299/389 (76%), Positives = 327/389 (84%), Gaps = 21/389 (5%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAA 61
+D P+TLYVGNLSRDVTE LILQLFSQIGPCK+CKMI + NDPYCFVEF+EHR AAA
Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAA 63
Query: 62 ALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTED 121
ALAAMNGRKI+GKEVKVNWATTPSSQKKDTS+ HFHVFVGDLSPEITTED
Sbjct: 64 ALAAMNGRKILGKEVKVNWATTPSSQKKDTSN-----------HFHVFVGDLSPEITTED 112
Query: 122 IKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
IK+AFAPFG+ISDARVVKDMATGKSKGYGFVSF+NK DAENAI MGGQWLGGRQIRTNW
Sbjct: 113 IKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 172
Query: 182 ATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIM 241
ATRKPPAPKST E+NTKQL +++VVNQSSP NCTVYCGG+ SGLT+QLMRQTFSPFGQIM
Sbjct: 173 ATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIM 232
Query: 242 EIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIG 301
EIRVFP+KGYSFVRF++HESAAHAIVSVNGTTIEGHVVKCYWGKE+ DM Q Q+
Sbjct: 233 EIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQ---QVD 289
Query: 302 YPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPNYGV 360
Y Q +GQW Q YGN QQ GQYM NGWQVP YG+YGQ WNQQGF QS SA WMG +G
Sbjct: 290 YSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-GFGA 347
Query: 361 QPPQGQNGSML---PNQPSGYRVAGYETQ 386
QPPQGQ + PNQ +GY +A Y+TQ
Sbjct: 348 QPPQGQAPPPVIPPPNQ-AGYGMASYQTQ 375
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 588 bits (1515), Expect = e-168
Identities = 299/406 (73%), Positives = 327/406 (80%), Gaps = 38/406 (9%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDT-----------------AG 44
+D P+TLYVGNLSRDVTE LILQLFSQIGPCK+CKMI +
Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTS 63
Query: 45 NDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQD 104
NDPYCFVEF+EHR AAAALAAMNGRKI+GKEVKVNWATTPSSQKKDTS+
Sbjct: 64 NDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSN----------- 112
Query: 105 HFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAI 164
HFHVFVGDLSPEITTEDIK+AFAPFG+ISDARVVKDMATGKSKGYGFVSF+NK DAENAI
Sbjct: 113 HFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAI 172
Query: 165 QQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSG 224
MGGQWLGGRQIRTNWATRKPPAPKST E+NTKQL +++VVNQSSP NCTVYCGG+ SG
Sbjct: 173 VHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASG 232
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWG 284
LT+QLMRQTFSPFGQIMEIRVFP+KGYSFVRF++HESAAHAIVSVNGTTIEGHVVKCYWG
Sbjct: 233 LTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWG 292
Query: 285 KETLDMINPVQQQNQIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGF 344
KE+ DM Q Q+ Y Q +GQW Q YGN QQ GQYM NGWQVP YG+YGQ WNQQGF
Sbjct: 293 KESPDMTKNFQ---QVDYSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGF 348
Query: 345 NQTQS-SAPWMGPNYGVQPPQGQNGSML---PNQPSGYRVAGYETQ 386
QS SA WMG +G QPPQGQ + PNQ +GY +A Y+TQ
Sbjct: 349 GVDQSPSAAWMG-GFGAQPPQGQAPPPVIPPPNQ-AGYGMASYQTQ 392
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 120 bits (300), Expect = 3e-27
Identities = 74/270 (27%), Positives = 132/270 (48%), Gaps = 16/270 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
++V NL + + + S G +C ++ D G+ Y FV F H A A+ MNG
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
+ G++V V + ++ + + R+++ +V++ + ++ E +K F
Sbjct: 161 MLLNGRKVFVGQFKSRKEREAELGA-------RAKEFPNVYIKNFGEDMDDERLKDLFGK 213
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
FG +V+ D +GKSKG+GFVSF DA+ A+ +M G+ L G+QI A +K
Sbjct: 214 FGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +Q+ D + +Y + G+ ++ +R+ FSPFG I +V +
Sbjct: 273 -QTELKRTFEQMKQDRITRYQV---VNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMME 328
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
KG+ FV F+S E A A+ +NG +
Sbjct: 329 GGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
Score = 108 bits (271), Expect = 6e-24
Identities = 79/276 (28%), Positives = 124/276 (44%), Gaps = 36/276 (13%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T+G+ Y +V F + A AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
MN I GK V++ W+ S +K ++FV +L I + +
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVG-------------NIFVKNLDKSINNKALYDT 118
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
+ FG I VV D SKGYGFV F AE AI++M G L GR++
Sbjct: 119 VSAFGNILSCNVVCD--ENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFV------ 170
Query: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245
++S ++ + + + VY + ++ ++ F FG + ++V
Sbjct: 171 -----GQFKSRKER---EAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKV 222
Query: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEG 276
D KG+ FV F HE A A+ +NG + G
Sbjct: 223 MTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNG 258
Score = 92.4 bits (228), Expect = 6e-19
Identities = 71/249 (28%), Positives = 118/249 (47%), Gaps = 22/249 (8%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N D+ + + LF + GP + K++ D +G + FV F H A A+ MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVST--QRSQDHF------HVFVGDLSPEITT 119
G+++ GK++ V A QKK + + T Q QD +++V +L I
Sbjct: 253 GKELNGKQIYVGRA-----QKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDD 307
Query: 120 EDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRT 179
E ++ AF+PFG I+ A+V+ M G+SKG+GFV F + +A A+ +M G+ + + +
Sbjct: 308 ERLRKAFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYV 365
Query: 180 NWATRKPPAPK-STYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFG 238
A RK T E + S V NQ +P + G + + + + P
Sbjct: 366 ALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPS-----GYFMTAVPQTQNHAAYYPPS 420
Query: 239 QIMEIRVFP 247
QI +R P
Sbjct: 421 QIARLRPSP 429
Score = 85.9 bits (211), Expect = 6e-17
Identities = 51/176 (28%), Positives = 81/176 (46%), Gaps = 24/176 (13%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
++VGDL P++T + F+P G I R+ +D+ T S Y +V+F + DAE+A+ M
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
+ G+ +R W+ R P KS + ++ + +
Sbjct: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFVKNLDKSINN 112
Query: 228 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
+ + T S FG I+ V D KGY FV F +HE+A AI +NG + G V
Sbjct: 113 KALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKV 168
Score = 49.3 bits (116), Expect = 6e-06
Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 8/88 (9%)
Query: 206 VNQSSPS--NCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFN 257
+N S+PS ++Y G + +TE ++ + FSP G I+ IR+ D Y++V F
Sbjct: 1 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 60
Query: 258 SHESAAHAIVSVNGTTIEGHVVKCYWGK 285
+ A HA+ ++N I+G V+ W +
Sbjct: 61 HTKDAEHALDTMNFDVIKGKPVRIMWSQ 88
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 119 bits (297), Expect = 6e-27
Identities = 73/270 (27%), Positives = 132/270 (48%), Gaps = 16/270 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
+ ++V V + ++ + + R+++ +V++ + ++ E +K F
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGA-------RAKEFTNVYIKNFGEDMDDERLKDLFGK 213
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
FG +V+ D +GKSKG+GFVSF DA+ A+ +M G+ L G+QI A +K
Sbjct: 214 FGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +Q+ D + +Y + G+ ++ +R+ FSPFG I +V +
Sbjct: 273 -QTELKRKFEQMKQDRITRY---QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME 328
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
KG+ FV F+S E A A+ +NG +
Sbjct: 329 GGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
Score = 105 bits (262), Expect = 7e-23
Identities = 77/276 (27%), Positives = 124/276 (44%), Gaps = 36/276 (13%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
MN I GK V++ W+ S +K ++F+ +L I + +
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVG-------------NIFIKNLDKSIDNKALYDT 118
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
F+ FG I +VV D SKGYGFV F + AE AI++M G L R++
Sbjct: 119 FSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV------ 170
Query: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245
++S ++ + + + VY + ++ ++ F FG + ++V
Sbjct: 171 -----GRFKSRKER---EAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKV 222
Query: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEG 276
D KG+ FV F HE A A+ +NG + G
Sbjct: 223 MTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNG 258
Score = 86.7 bits (213), Expect = 3e-17
Identities = 63/251 (25%), Positives = 117/251 (46%), Gaps = 20/251 (7%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N D+ + + LF + GP + K++ D +G + FV F H A A+ MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHF------HVFVGDLSPEITTED 121
G+++ GK++ V A ++ + Q QD +++V +L I E
Sbjct: 253 GKELNGKQIYVGRAQKKVERQTELKRKF---EQMKQDRITRYQGVNLYVKNLDDGIDDER 309
Query: 122 IKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
++ F+PFG I+ A+V+ M G+SKG+GFV F + +A A+ +M G+ + + +
Sbjct: 310 LRKEFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVAL 367
Query: 182 ATRKPPAPKSTYESNTKQLSY-----DEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSP 236
A RK ++++ + V+N P+ + Y + + + R + P
Sbjct: 368 AQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGY---FMAAIPQTQNRAAYYP 424
Query: 237 FGQIMEIRVFP 247
QI ++R P
Sbjct: 425 PSQIAQLRPSP 435
Score = 86.3 bits (212), Expect = 4e-17
Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 24/176 (13%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
++VGDL P++T + F+P G I RV +DM T +S GY +V+F DAE A+ M
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
+ G+ +R W+ R P KS + ++ + +
Sbjct: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFIKNLDKSIDN 112
Query: 228 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
+ + TFS FG I+ +V D KGY FV F + E+A AI +NG + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168
Score = 47.4 bits (111), Expect = 2e-05
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 8/88 (9%)
Query: 206 VNQSSPSN--CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFN 257
+N S+PS ++Y G + +TE ++ + FSP G I+ IRV D GY++V F
Sbjct: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
Query: 258 SHESAAHAIVSVNGTTIEGHVVKCYWGK 285
A A+ ++N I+G V+ W +
Sbjct: 61 QPADAERALDTMNFDVIKGKPVRIMWSQ 88
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 115 bits (287), Expect = 9e-26
Identities = 70/270 (25%), Positives = 133/270 (49%), Gaps = 16/270 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
+ ++V V + ++ + + ++++ +V++ + E+ E +K F+
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGA-------KAKEFTNVYIKNFGEEVDDESLKELFSQ 213
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
FG+ +V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K
Sbjct: 214 FGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +QL + + S +Y + + ++ +R+ FSPFG I +V +
Sbjct: 273 -QAELKRKFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE 328
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
KG+ FV F+S E A A+ +NG +
Sbjct: 329 DGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
Score = 107 bits (266), Expect = 2e-23
Identities = 78/279 (27%), Positives = 126/279 (45%), Gaps = 36/279 (12%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
MN I GK +++ W+ S +K +VF+ +L I + +
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVG-------------NVFIKNLDKSIDNKALYDT 118
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
F+ FG I +VV D SKGY FV F + A+ AI++M G L R++ + R
Sbjct: 119 FSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRF 173
Query: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245
+ E K + VY + ++ +++ FS FG+ + ++V
Sbjct: 174 KSRKEREAELGAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKV 222
Query: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
D KG+ FV + HE A A+ +NG I G ++
Sbjct: 223 MRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.7 bits (208), Expect = 1e-16
Identities = 51/181 (28%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHF---HVFVGDLSPEITTEDIKA 124
G++I GK + V A ++ + Q + ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 185 K 185
K
Sbjct: 371 K 371
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 209 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 262
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 263 AHAIVSVNGTTIEGHVVKCYWGK 285
A+ ++N I+G ++ W +
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 115 bits (287), Expect = 9e-26
Identities = 70/270 (25%), Positives = 133/270 (49%), Gaps = 16/270 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
+ ++V V + ++ + + ++++ +V++ + E+ E +K F+
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGA-------KAKEFTNVYIKNFGEEVDDESLKELFSQ 213
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
FG+ +V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K
Sbjct: 214 FGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +QL + + S +Y + + ++ +R+ FSPFG I +V +
Sbjct: 273 -QAELKRKFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE 328
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
KG+ FV F+S E A A+ +NG +
Sbjct: 329 DGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
Score = 107 bits (266), Expect = 2e-23
Identities = 78/279 (27%), Positives = 126/279 (45%), Gaps = 36/279 (12%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
MN I GK +++ W+ S +K +VF+ +L I + +
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVG-------------NVFIKNLDKSIDNKALYDT 118
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
F+ FG I +VV D SKGY FV F + A+ AI++M G L R++ + R
Sbjct: 119 FSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRF 173
Query: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245
+ E K + VY + ++ +++ FS FG+ + ++V
Sbjct: 174 KSRKEREAELGAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKV 222
Query: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
D KG+ FV + HE A A+ +NG I G ++
Sbjct: 223 MRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.7 bits (208), Expect = 1e-16
Identities = 51/181 (28%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHF---HVFVGDLSPEITTEDIKA 124
G++I GK + V A ++ + Q + ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 185 K 185
K
Sbjct: 371 K 371
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 209 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 262
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 263 AHAIVSVNGTTIEGHVVKCYWGK 285
A+ ++N I+G ++ W +
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 115 bits (287), Expect = 9e-26
Identities = 70/270 (25%), Positives = 133/270 (49%), Gaps = 16/270 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
+ ++V V + ++ + + ++++ +V++ + E+ E +K F+
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGA-------KAKEFTNVYIKNFGEEVDDESLKELFSQ 213
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
FG+ +V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K
Sbjct: 214 FGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +QL + + S +Y + + ++ +R+ FSPFG I +V +
Sbjct: 273 -QAELKRKFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE 328
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
KG+ FV F+S E A A+ +NG +
Sbjct: 329 DGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
Score = 107 bits (266), Expect = 2e-23
Identities = 78/279 (27%), Positives = 126/279 (45%), Gaps = 36/279 (12%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
MN I GK +++ W+ S +K +VF+ +L I + +
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVG-------------NVFIKNLDKSIDNKALYDT 118
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
F+ FG I +VV D SKGY FV F + A+ AI++M G L R++ + R
Sbjct: 119 FSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRF 173
Query: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245
+ E K + VY + ++ +++ FS FG+ + ++V
Sbjct: 174 KSRKEREAELGAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKV 222
Query: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
D KG+ FV + HE A A+ +NG I G ++
Sbjct: 223 MRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.7 bits (208), Expect = 1e-16
Identities = 51/181 (28%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHF---HVFVGDLSPEITTEDIKA 124
G++I GK + V A ++ + Q + ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 185 K 185
K
Sbjct: 371 K 371
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 209 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 262
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 263 AHAIVSVNGTTIEGHVVKCYWGK 285
A+ ++N I+G ++ W +
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 109 bits (272), Expect = 5e-24
Identities = 79/280 (28%), Positives = 133/280 (47%), Gaps = 38/280 (13%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L DVTE L+ + FS +GP + ++ D T + Y +V F + A AL
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
MN I GK +++ W+ + ++ + VF+ +L I + +
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGN-------------VFIKNLDKSIDNKTLYEH 117
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
F+ FG+I ++V+ D SKGY FV F N+ A+ AI++M G+ L G ++
Sbjct: 118 FSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKV-------- 167
Query: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCT-VYCGGVTSGLTEQLMRQTFSPFGQIMEIR 244
+ K E +S S T VY + ++ ++ FS +G+ + ++
Sbjct: 168 -------FVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVK 220
Query: 245 VFPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
V D KG+ FV F+SHE+A A+ +NG I G ++
Sbjct: 221 VMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLI 260
Score = 100 bits (248), Expect = 3e-21
Identities = 65/267 (24%), Positives = 130/267 (48%), Gaps = 16/267 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + + FS G + K++ D G+ Y FV F A A+ MNG
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
+ + G +V V ++ + S ++ + +V++ + ++ E +K F+
Sbjct: 160 KLLKGCKVFVGRFKNRKDREAELRS-------KASEFTNVYIKNFGGDMDDERLKDVFSK 212
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
+G+ +V+ D ++GKSKG+GFVSF + A+ A+++M G+ + G+ I A +K
Sbjct: 213 YGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVER 271
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +QL + + +Y + + ++ +R FS FG I ++V +
Sbjct: 272 -QAELKQMFEQLKRERI---RGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE 327
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNG 271
KG+ + F+S E A A+ +NG
Sbjct: 328 EGQSKGFGLICFSSPEDATKAMTEMNG 354
Score = 72.8 bits (177), Expect = 5e-13
Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+Y+ N D+ + + +FS+ G + K++ D++G + FV F H A A+ MN
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMN 251
Query: 68 GRKIMGKEVKVNWATTP---SSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKA 124
GR I G+ + V A ++ K R +++ +L I E ++
Sbjct: 252 GRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRN 311
Query: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
F+ FG IS +V+++ G+SKG+G + F + DA A+ +M G+ LG + + A R
Sbjct: 312 EFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 215 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 268
++Y G + + +TE L+ + FS G ++ IR+ D+ GY++V F A A+ +
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 269 VNGTTIEGHVVKCYWGK 285
+N I+G ++ W +
Sbjct: 71 MNFDIIKGKSIRLMWSQ 87
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 103 bits (256), Expect = 3e-22
Identities = 67/270 (24%), Positives = 125/270 (46%), Gaps = 15/270 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + + LFS G +CK++ D G+ Y +V F A A+ MNG
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
++ ++V V P + + V T+ +VFV ++ +I E +K F
Sbjct: 168 VRLNNRQVYVGRFKFPEERAAE------VRTRDRATFTNVFVKNIGDDIDDEKLKELFCE 221
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
+G +V++D A+GKSKG+GFV + A+ A+ + G+ + G+ + A +K
Sbjct: 222 YGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKK--- 277
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +S P +Y + + ++ +++ FS FG I +V +
Sbjct: 278 -IERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME 336
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
KG+ V F+S E A A+ +NG +
Sbjct: 337 VGQGKGFGVVCFSSFEEATKAVDEMNGRIV 366
Score = 93.2 bits (230), Expect = 4e-19
Identities = 76/278 (27%), Positives = 123/278 (44%), Gaps = 35/278 (12%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAM 66
LYVG+L DVTE ++ + F GP + ++ D P Y +V F A AL M
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
N I GK ++ W SQ D + V ++F+ +L I + F
Sbjct: 80 NFDLINGKPFRLMW-----SQPDDRLRKSGVG--------NIFIKNLDKSIDNRALFYLF 126
Query: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKP 186
+ FG I +VV D SKGY +V F + A AI M G L RQ+ K
Sbjct: 127 SAFGNILSCKVVCD--DNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVG--RFKF 182
Query: 187 PAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVF 246
P ++ EV + + V+ + + ++ +++ F +G ++V
Sbjct: 183 PEERAA-----------EVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVI 231
Query: 247 PD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
D KG+ FVR+ +HE+A A++ ++G +I+G V+
Sbjct: 232 RDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVL 269
Score = 71.6 bits (174), Expect = 1e-12
Identities = 45/173 (26%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
++V N+ D+ + + +LF + GP ++ K+I D +G + FV + H A A+ ++
Sbjct: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTS---SSTVVSTQRSQDHFHVFVGDLSPEITTEDIKA 124
G+ I GK + V A + + + + +++ +L I E +K
Sbjct: 261 GKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKE 320
Query: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI 177
F+ FG IS A+V+ M G+ KG+G V F + +A A+ +M G+ +G + +
Sbjct: 321 EFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
Score = 32.7 bits (73), Expect = 0.57
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 216 VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSV 269
+Y G + +TE ++ + F P G + R+ D GY +V F A A+ ++
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 270 NGTTIEGHVVKCYWGK 285
N I G + W +
Sbjct: 80 NFDLINGKPFRLMWSQ 95
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 99.4 bits (246), Expect = 5e-21
Identities = 76/301 (25%), Positives = 137/301 (45%), Gaps = 44/301 (14%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAA 65
+LYVG+L DVTEA++ + FS GP + ++ D A Y ++ F + A AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
MN + G+ +++ W+ +K ++F+ +L I + +
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVG-------------NIFIKNLEDSIDNKALYDT 118
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRT-NWATR 184
F+ FG I +V D S+G+GFV F A+ AI M G L R++ ++ +R
Sbjct: 119 FSTFGNILSCKVACD--EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSR 176
Query: 185 KPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIR 244
+ + E + L + + ++ P + + EQ ++ FS FG+++ ++
Sbjct: 177 R----EREAELGARALEFTNIYVKNLPVD-----------VDEQGLQDLFSQFGKMLSVK 221
Query: 245 VFPDKG-----YSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQ 299
V D + FV F HE A A+V +NG + G ++ Y G+ V++QN+
Sbjct: 222 VMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL--YAGRAQ----KRVERQNE 275
Query: 300 I 300
+
Sbjct: 276 L 276
Score = 96.7 bits (239), Expect = 3e-20
Identities = 63/270 (23%), Positives = 129/270 (47%), Gaps = 16/270 (5%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
+++ NL + + FS G +CK+ D G+ + FV F H A A+ MNG
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNG 160
Query: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
+ ++V V + ++ + + R+ + +++V +L ++ + ++ F+
Sbjct: 161 MLLNDRKVFVGHFKSRREREAELGA-------RALEFTNIYVKNLPVDVDEQGLQDLFSQ 213
Query: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
FG++ +V++D +G S+ +GFV+F +A+ A+ M G+ + GR + A +K
Sbjct: 214 FGKMLSVKVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRA-QKRVE 271
Query: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
++ + +Q+ D + +Y + + + +R+ FSP+G I +V +
Sbjct: 272 RQNELKRRFEQMKQDRLRRY---QGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE 328
Query: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
KG+ FV F+S E A A+ +NG +
Sbjct: 329 GGHSKGFGFVCFSSPEEATKAVTEMNGRIV 358
Score = 82.4 bits (202), Expect = 6e-16
Identities = 53/181 (29%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
+YV NL DV E + LFSQ G + K++ D +G+ + FV F +H A A+ MN
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
Query: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQ---RSQDHFHVFVGDLSPEITTEDIKA 124
G+++ G+ + A ++ + Q R +++V +L I + ++
Sbjct: 253 GKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRK 312
Query: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
F+P+G I+ A+V+ + G SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 313 EFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQR 370
Query: 185 K 185
K
Sbjct: 371 K 371
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 99.0 bits (245), Expect = 6e-21
Identities = 78/329 (23%), Positives = 145/329 (44%), Gaps = 66/329 (20%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 45 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 104
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 105 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 149
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 150 ELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPIT 209
Query: 181 WATRKPPAPKST-------YES-----------NTKQLSYDEVVNQS------SP----- 211
P+ KS+ Y+S ++ D ++N + SP
Sbjct: 210 VKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDG 269
Query: 212 --------------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGY 251
+ ++ ++ E ++ Q F PFG + ++V D KG+
Sbjct: 270 MTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGF 329
Query: 252 SFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
FV +++ AA AI S+NG + V++
Sbjct: 330 GFVTMTNYDEAAMAIASLNGYRLGDRVLQ 358
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/204 (26%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 79 NWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 138
N + PSS ++ S ++ V L +T E+ ++ F G I ++V
Sbjct: 22 NTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLV 81
Query: 139 KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198
+D TG+S GYGFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 82 RDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN-- 136
Query: 199 QLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYS 252
+Y G+ +T++ + Q FS +G+I+ R+ D +G
Sbjct: 137 -----------------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 179
Query: 253 FVRFNSHESAAHAIVSVNGTTIEG 276
F+RF+ A AI +NG G
Sbjct: 180 FIRFDKRIEAEEAIKGLNGQKPSG 203
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 52/229 (22%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LYV L + +T+ + QLFSQ G ++++D T + F+ F + A A+ +
Sbjct: 137 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 196
Query: 67 NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVVST--QRSQDHFH--------------- 107
NG+K G + + V +A PS + S + + +R H
Sbjct: 197 NGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMA 256
Query: 108 -------------------------------VFVGDLSPEITTEDIKAAFAPFGRISDAR 136
+FV +LSP+ + F PFG +++ +
Sbjct: 257 YGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK 316
Query: 137 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
V++D T K KG+GFV+ N +A AI + G LG R ++ ++ T K
Sbjct: 317 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 365
Score = 32.0 bits (71), Expect = 0.97
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 60 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 119
Query: 279 VKCYWGK 285
+K + +
Sbjct: 120 IKVSYAR 126
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 99.0 bits (245), Expect = 6e-21
Identities = 78/329 (23%), Positives = 145/329 (44%), Gaps = 66/329 (20%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 146
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 147 ELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPIT 206
Query: 181 WATRKPPAPKST-------YES-----------NTKQLSYDEVVNQS------SP----- 211
P+ KS+ Y+S ++ D ++N + SP
Sbjct: 207 VKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDG 266
Query: 212 --------------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGY 251
+ ++ ++ E ++ Q F PFG + ++V D KG+
Sbjct: 267 MTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGF 326
Query: 252 SFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
FV +++ AA AI S+NG + V++
Sbjct: 327 GFVTMTNYDEAAMAIASLNGYRLGDRVLQ 355
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/204 (26%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 79 NWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 138
N + PSS ++ S ++ V L +T E+ ++ F G I ++V
Sbjct: 19 NTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLV 78
Query: 139 KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198
+D TG+S GYGFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 79 RDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN-- 133
Query: 199 QLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYS 252
+Y G+ +T++ + Q FS +G+I+ R+ D +G
Sbjct: 134 -----------------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 176
Query: 253 FVRFNSHESAAHAIVSVNGTTIEG 276
F+RF+ A AI +NG G
Sbjct: 177 FIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 52/229 (22%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LYV L + +T+ + QLFSQ G ++++D T + F+ F + A A+ +
Sbjct: 134 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 193
Query: 67 NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVVST--QRSQDHFH--------------- 107
NG+K G + + V +A PS + S + + +R H
Sbjct: 194 NGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMA 253
Query: 108 -------------------------------VFVGDLSPEITTEDIKAAFAPFGRISDAR 136
+FV +LSP+ + F PFG +++ +
Sbjct: 254 YGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK 313
Query: 137 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
V++D T K KG+GFV+ N +A AI + G LG R ++ ++ T K
Sbjct: 314 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 362
Score = 32.0 bits (71), Expect = 0.97
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
Query: 279 VKCYWGK 285
+K + +
Sbjct: 117 IKVSYAR 123
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 99.0 bits (245), Expect = 6e-21
Identities = 78/329 (23%), Positives = 145/329 (44%), Gaps = 66/329 (20%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 163
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 164 ELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPIT 223
Query: 181 WATRKPPAPKST-------YES-----------NTKQLSYDEVVNQS------SP----- 211
P+ KS+ Y+S ++ D ++N + SP
Sbjct: 224 VKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDG 283
Query: 212 --------------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGY 251
+ ++ ++ E ++ Q F PFG + ++V D KG+
Sbjct: 284 MTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGF 343
Query: 252 SFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
FV +++ AA AI S+NG + V++
Sbjct: 344 GFVTMTNYDEAAMAIASLNGYRLGDRVLQ 372
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/204 (26%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 79 NWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 138
N + PSS ++ S ++ V L +T E+ ++ F G I ++V
Sbjct: 36 NTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLV 95
Query: 139 KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198
+D TG+S GYGFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 96 RDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN-- 150
Query: 199 QLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYS 252
+Y G+ +T++ + Q FS +G+I+ R+ D +G
Sbjct: 151 -----------------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 193
Query: 253 FVRFNSHESAAHAIVSVNGTTIEG 276
F+RF+ A AI +NG G
Sbjct: 194 FIRFDKRIEAEEAIKGLNGQKPSG 217
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 52/229 (22%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LYV L + +T+ + QLFSQ G ++++D T + F+ F + A A+ +
Sbjct: 151 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 210
Query: 67 NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVVST--QRSQDHFH--------------- 107
NG+K G + + V +A PS + S + + +R H
Sbjct: 211 NGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMA 270
Query: 108 -------------------------------VFVGDLSPEITTEDIKAAFAPFGRISDAR 136
+FV +LSP+ + F PFG +++ +
Sbjct: 271 YGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK 330
Query: 137 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
V++D T K KG+GFV+ N +A AI + G LG R ++ ++ T K
Sbjct: 331 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 379
Score = 32.0 bits (71), Expect = 0.97
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 74 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 133
Query: 279 VKCYWGK 285
+K + +
Sbjct: 134 IKVSYAR 140
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 99.0 bits (245), Expect = 6e-21
Identities = 78/329 (23%), Positives = 145/329 (44%), Gaps = 66/329 (20%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 146
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 147 ELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPIT 206
Query: 181 WATRKPPAPKST-------YES-----------NTKQLSYDEVVNQS------SP----- 211
P+ KS+ Y+S ++ D ++N + SP
Sbjct: 207 VKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDG 266
Query: 212 --------------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGY 251
+ ++ ++ E ++ Q F PFG + ++V D KG+
Sbjct: 267 MTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGF 326
Query: 252 SFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
FV +++ AA AI S+NG + V++
Sbjct: 327 GFVTMTNYDEAAMAIASLNGYRLGDRVLQ 355
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/204 (26%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 79 NWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 138
N + PSS ++ S ++ V L +T E+ ++ F G I ++V
Sbjct: 19 NTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLV 78
Query: 139 KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198
+D TG+S GYGFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 79 RDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN-- 133
Query: 199 QLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYS 252
+Y G+ +T++ + Q FS +G+I+ R+ D +G
Sbjct: 134 -----------------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 176
Query: 253 FVRFNSHESAAHAIVSVNGTTIEG 276
F+RF+ A AI +NG G
Sbjct: 177 FIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 52/229 (22%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LYV L + +T+ + QLFSQ G ++++D T + F+ F + A A+ +
Sbjct: 134 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 193
Query: 67 NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVVST--QRSQDHFH--------------- 107
NG+K G + + V +A PS + S + + +R H
Sbjct: 194 NGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMA 253
Query: 108 -------------------------------VFVGDLSPEITTEDIKAAFAPFGRISDAR 136
+FV +LSP+ + F PFG +++ +
Sbjct: 254 YGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK 313
Query: 137 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
V++D T K KG+GFV+ N +A AI + G LG R ++ ++ T K
Sbjct: 314 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 362
Score = 32.0 bits (71), Expect = 0.97
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
Query: 279 VKCYWGK 285
+K + +
Sbjct: 117 IKVSYAR 123
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 97.4 bits (241), Expect = 2e-20
Identities = 82/343 (23%), Positives = 146/343 (42%), Gaps = 80/343 (23%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 146
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 147 ELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPIT 206
Query: 181 WATRKPPAPKST-------YES-----------NTKQLSYDEVVNQS-----------SP 211
P+ KS+ Y+S ++ D ++N + P
Sbjct: 207 VKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPP 266
Query: 212 SNCTVYCGGVT-SGLT---------------------------EQLMRQTFSPFGQIMEI 243
S C +T G+T E ++ Q F PFG + +
Sbjct: 267 SACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNV 326
Query: 244 RVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
+V D KG+ FV +++ AA AI S+NG + V++
Sbjct: 327 KVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 369
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/204 (26%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 79 NWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 138
N + PSS ++ S ++ V L +T E+ ++ F G I ++V
Sbjct: 19 NTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLV 78
Query: 139 KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198
+D TG+S GYGFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 79 RDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN-- 133
Query: 199 QLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYS 252
+Y G+ +T++ + Q FS +G+I+ R+ D +G
Sbjct: 134 -----------------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 176
Query: 253 FVRFNSHESAAHAIVSVNGTTIEG 276
F+RF+ A AI +NG G
Sbjct: 177 FIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 58.5 bits (140), Expect = 1e-08
Identities = 28/78 (35%), Positives = 46/78 (58%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
+FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 168 GGQWLGGRQIRTNWATRK 185
G LG R ++ ++ T K
Sbjct: 359 NGYRLGDRVLQVSFKTNK 376
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 67 NGRKIMGKEVKVNWAT 82
NG ++ + ++V++ T
Sbjct: 359 NGYRLGDRVLQVSFKT 374
Score = 32.0 bits (71), Expect = 0.97
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
Query: 279 VKCYWGK 285
+K + +
Sbjct: 117 IKVSYAR 123
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 97.4 bits (241), Expect = 2e-20
Identities = 77/332 (23%), Positives = 146/332 (43%), Gaps = 72/332 (21%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
++ L V L +++T+ + LF IG ++CK++ D T + Y FV + + + A
Sbjct: 35 EDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 94
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 95 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 139
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQ---------- 170
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ
Sbjct: 140 ELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPIT 199
Query: 171 --WLGGRQIRTNWA---------TRKPPAPKSTYESNTKQLSYDEVVNQS------SP-- 211
+ +TN A R+ P P + ++ D ++N + SP
Sbjct: 200 VKFANNPSQKTNQAILSQLYQSPNRRYPGPLA---QQAQRFRLDNLLNMAYGVKRFSPMT 256
Query: 212 -----------------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------ 248
+ ++ + E ++ Q F PFG + ++V D
Sbjct: 257 IDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKC 316
Query: 249 KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
KG+ FV +++ AA AI S+NG + V++
Sbjct: 317 KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 348
Score = 82.8 bits (203), Expect = 5e-16
Identities = 69/253 (27%), Positives = 112/253 (44%), Gaps = 40/253 (15%)
Query: 93 SSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFV 152
SS V S ++ V L +T E++K+ F G I ++V+D TG+S GYGFV
Sbjct: 26 SSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFV 85
Query: 153 SFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPS 212
++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 86 NYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN---------------- 126
Query: 213 NCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAI 266
+Y G+ +T++ + Q FS +G+I+ R+ D +G F+RF+ A AI
Sbjct: 127 ---LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAI 183
Query: 267 VSVNGTTIEGHVVKCYWGKETLDM---INPVQQQNQIGYPQPYGQWGQWYGN--AQQIGQ 321
+NG G E + + NP Q+ NQ Q Y + Y AQQ +
Sbjct: 184 KGLNGQKPPG-------ATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQR 236
Query: 322 YMPNGWQVPAYGM 334
+ + AYG+
Sbjct: 237 FRLDNLLNMAYGV 249
Score = 66.6 bits (161), Expect = 4e-11
Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 52/229 (22%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LYV L + +T+ + QLFSQ G ++++D T + F+ F + A A+ +
Sbjct: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
Query: 67 NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVVST----------QRSQDH--------- 105
NG+K G + + V +A PS + S + + Q++Q
Sbjct: 187 NGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMA 246
Query: 106 -----------------------------FHVFVGDLSPEITTEDIKAAFAPFGRISDAR 136
+ +FV +L+P+ + F PFG +++ +
Sbjct: 247 YGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVK 306
Query: 137 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
V++D T K KG+GFV+ N +A AI + G LG R ++ ++ T K
Sbjct: 307 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 355
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 96.3 bits (238), Expect = 4e-20
Identities = 81/330 (24%), Positives = 144/330 (43%), Gaps = 67/330 (20%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + A
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG K+ K +KV++A S+ +D + ++V L ++ +
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDAN---------------LYVSGLPKTMSQK 139
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 140 EMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPIT 199
Query: 181 WATRKPPAPKS-------TYESN-----------TKQLSYDEVVNQS------SPSNCTV 216
P+ K+ Y+S+ T++ D ++N + SP
Sbjct: 200 VKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDG 259
Query: 217 YCGGVTSGLT--------------------EQLMRQTFSPFGQIMEIRVFPD------KG 250
G GL+ E ++ Q F PFG + ++V D KG
Sbjct: 260 MSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKG 319
Query: 251 YSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
+ FV +++ AA AI S+NG + V++
Sbjct: 320 FGFVTMTNYDEAAMAIASLNGYRLGERVLQ 349
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/231 (25%), Positives = 98/231 (42%), Gaps = 55/231 (23%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LYV L + +++ + QLFSQ G ++++D T + F+ F + A A+ +
Sbjct: 127 LYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 67 NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVV---STQRSQDHFH-------------- 107
NG+K +G + + V +A P SQK + T + S +R H
Sbjct: 187 NGQKPLGAAEPITVKFANNP-SQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNM 245
Query: 108 ---------------------------------VFVGDLSPEITTEDIKAAFAPFGRISD 134
+FV +LSPE + F PFG +++
Sbjct: 246 AYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTN 305
Query: 135 ARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
+V++D T K KG+GFV+ N +A AI + G LG R ++ ++ T K
Sbjct: 306 VKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSK 356
Score = 30.0 bits (66), Expect = 3.7
Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T+ + F G I ++ DK GY FV ++ A AI ++NG ++
Sbjct: 50 MTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKT 109
Query: 279 VKCYWGK 285
+K + +
Sbjct: 110 IKVSYAR 116
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 94.4 bits (233), Expect = 2e-19
Identities = 64/187 (34%), Positives = 96/187 (51%), Gaps = 17/187 (9%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E T+YVG L V+E L+ +LF Q GP N M D T + Y FVEF A
Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67
Query: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITT 119
A+ MN K+ GK ++VN A S+ K+ ++F+G+L PEI
Sbjct: 68 DYAIKIMNMIKLYGKPIRVNKA---SAHNKNLDVGA-----------NIFIGNLDPEIDE 113
Query: 120 EDIKAAFAPFGRISDA-RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178
+ + F+ FG I ++++D TG SKGY F++F + ++ AI+ M GQ+L R I
Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPIT 173
Query: 179 TNWATRK 185
++A +K
Sbjct: 174 VSYAFKK 180
Score = 72.0 bits (175), Expect = 8e-13
Identities = 53/180 (29%), Positives = 89/180 (49%), Gaps = 29/180 (16%)
Query: 99 TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW 158
++R+QD V+VG L +++ + F G + + + KD TG+ +GYGFV F ++
Sbjct: 7 SERNQDAT-VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEE 65
Query: 159 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC 218
DA+ AI+ M L G+ IR N A+ N++ ++
Sbjct: 66 DADYAIKIMNMIKLYGKPIRVNKASAH---------------------NKNLDVGANIFI 104
Query: 219 GGVTSGLTEQLMRQTFSPFGQIME---IRVFPD----KGYSFVRFNSHESAAHAIVSVNG 271
G + + E+L+ TFS FG I++ I PD KGY+F+ F S +++ AI ++NG
Sbjct: 105 GNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNG 164
Score = 45.1 bits (105), Expect = 1e-04
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIM---DTAGNDPYCFVEFHEHRHAAAALAA 65
+++GNL ++ E L+ FS G IM DT + Y F+ F + AA+ A
Sbjct: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161
Query: 66 MNGRKIMGKEVKVNWATTPSS--QKKDTSSSTVVSTQR---SQDHFHVFVGDLSP 115
MNG+ + + + V++A S ++ +++ +++ Q D H D P
Sbjct: 162 MNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPP 216
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 93.6 bits (231), Expect = 3e-19
Identities = 81/337 (24%), Positives = 144/337 (42%), Gaps = 74/337 (21%)
Query: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + A
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
A+ +NG K+ K +KV++A S+ +D + ++V L ++ +
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDAN---------------LYVSGLPKTMSQK 139
Query: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 140 EMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPIT 199
Query: 181 WATRKPPAPKS-------TYESN-----------TKQLSYDEVVNQS------------- 209
P+ K+ Y+S+ T++ D ++N +
Sbjct: 200 VKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARF 259
Query: 210 SPSNCTVYCGGVTSGLT--------------------EQLMRQTFSPFGQIMEIRVFPD- 248
SP G GL+ E ++ Q F PFG + ++V D
Sbjct: 260 SPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDF 319
Query: 249 -----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
KG+ FV +++ AA AI S+NG + V++
Sbjct: 320 TTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQ 356
Score = 60.1 bits (144), Expect = 3e-09
Identities = 29/78 (37%), Positives = 46/78 (58%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
+FV +LSPE + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 168 GGQWLGGRQIRTNWATRK 185
G LG R ++ ++ T K
Sbjct: 346 NGYRLGERVLQVSFKTSK 363
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
++V NLS + E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 67 NGRKIMGKEVKVNWATT 83
NG ++ + ++V++ T+
Sbjct: 346 NGYRLGERVLQVSFKTS 362
Score = 30.0 bits (66), Expect = 3.7
Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T+ + F G I ++ DK GY FV ++ A AI ++NG ++
Sbjct: 50 MTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKT 109
Query: 279 VKCYWGK 285
+K + +
Sbjct: 110 IKVSYAR 116
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 92.8 bits (229), Expect = 5e-19
Identities = 82/303 (27%), Positives = 133/303 (43%), Gaps = 57/303 (18%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGND-PYCFVEFHEHRHAAAALAAM 66
L V L +++T+ + LFS IG ++ K+I D AG+ Y FV + + A A+ +
Sbjct: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
Query: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
NG ++ K +KV++A S KD ++++ L +T +D++ F
Sbjct: 82 NGLRLQSKTIKVSYARPSSEVIKDA---------------NLYISGLPRTMTQKDVEDMF 126
Query: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGG--RQIRTNWATR 184
+ FGRI ++RV+ D TG S+G F+ F + +AE AI G G I +A
Sbjct: 127 SRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAA- 185
Query: 185 KPPAPKST------YESNTKQ------------------------LSYDEVVNQSSPSNC 214
P K+ Y S ++ LS V +S C
Sbjct: 186 NPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWC 245
Query: 215 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVS 268
++ + E ++ Q F PFG + ++V D KG+ FV ++E AA AI S
Sbjct: 246 -IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIAS 304
Query: 269 VNG 271
+NG
Sbjct: 305 LNG 307
Score = 76.3 bits (186), Expect = 4e-14
Identities = 48/171 (28%), Positives = 84/171 (49%), Gaps = 28/171 (16%)
Query: 107 HVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQ 166
++ V L +T +++++ F+ G + A++++D G S GYGFV++ DAE AI
Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
Query: 167 MGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLT 226
+ G L + I+ ++A P S EV+ ++ +Y G+ +T
Sbjct: 81 LNGLRLQSKTIKVSYA-----RPSS------------EVIKDAN-----LYISGLPRTMT 118
Query: 227 EQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNG 271
++ + FS FG+I+ RV D +G +F+RF+ A AI S NG
Sbjct: 119 QKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
Score = 67.4 bits (163), Expect = 2e-11
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 39/216 (18%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
LY+ L R +T+ + +FS+ G N ++++D T + F+ F + A A+ +
Sbjct: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
Query: 67 NGRKIMGKE--VKVNWATTPSSQKKDTSSSTVVSTQRSQ-------------------DH 105
NG K G + V +A P+ K S + + + DH
Sbjct: 168 NGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDH 227
Query: 106 FH----------------VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGY 149
+F+ +L + + F PFG +++ +V++D T K KG+
Sbjct: 228 MSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
Query: 150 GFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
GFV+ N +A AI + G LG + ++ ++ T K
Sbjct: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
Score = 37.0 bits (84), Expect = 0.030
Identities = 18/73 (24%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
+T+ +R FS G++ ++ DK GY FV + + + A AI ++NG ++
Sbjct: 31 MTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKT 90
Query: 279 VKCYWGKETLDMI 291
+K + + + ++I
Sbjct: 91 IKVSYARPSSEVI 103
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 82.8 bits (203), Expect = 5e-16
Identities = 52/186 (27%), Positives = 89/186 (47%), Gaps = 7/186 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
N + G+ +KV + + + ++ ++V + +++ +DIK+ F
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLA----EEARAFNRIYVASVHQDLSDDDIKSVF 203
Query: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKP 186
FG+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A P
Sbjct: 204 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TP 262
Query: 187 PAPKST 192
P P T
Sbjct: 263 PMPLLT 268
Score = 69.3 bits (168), Expect = 5e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 196
Query: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 197 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 255
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 214 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 267
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 86 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 145
Query: 268 SVNGTTIEGHVVK 280
+N + G +K
Sbjct: 146 QMNSVMLGGRNIK 158
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 82.8 bits (203), Expect = 5e-16
Identities = 52/186 (27%), Positives = 89/186 (47%), Gaps = 7/186 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
N + G+ +KV + + + ++ ++V + +++ +DIK+ F
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLA----EEARAFNRIYVASVHQDLSDDDIKSVF 229
Query: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKP 186
FG+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A P
Sbjct: 230 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TP 288
Query: 187 PAPKST 192
P P T
Sbjct: 289 PMPLLT 294
Score = 69.3 bits (168), Expect = 5e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 222
Query: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 223 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 281
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 214 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 267
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 112 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 171
Query: 268 SVNGTTIEGHVVK 280
+N + G +K
Sbjct: 172 QMNSVMLGGRNIK 184
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 82.8 bits (203), Expect = 5e-16
Identities = 52/186 (27%), Positives = 89/186 (47%), Gaps = 7/186 (3%)
Query: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
N + G+ +KV + + + ++ ++V + +++ +DIK+ F
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLA----EEARAFNRIYVASVHQDLSDDDIKSVF 246
Query: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKP 186
FG+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A P
Sbjct: 247 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TP 305
Query: 187 PAPKST 192
P P T
Sbjct: 306 PMPLLT 311
Score = 69.3 bits (168), Expect = 5e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 239
Query: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 240 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 298
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 214 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 267
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 129 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 188
Query: 268 SVNGTTIEGHVVK 280
+N + G +K
Sbjct: 189 QMNSVMLGGRNIK 201
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 79.7 bits (195), Expect = 4e-15
Identities = 50/194 (25%), Positives = 101/194 (52%), Gaps = 8/194 (4%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF +
Sbjct: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
Query: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR-SQDHFHVFVGDLSPEIT 118
A+ + G++++G + V S +K+ +++ + Q+ S ++VG L IT
Sbjct: 208 PLAIG-LTGQRVLGVPIIVQ----ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNIT 262
Query: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178
+ ++ F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++
Sbjct: 263 EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
Query: 179 TNWATRKPPAPKST 192
T + A ++
Sbjct: 323 VGHVTERTDASSAS 336
Score = 72.0 bits (175), Expect = 8e-13
Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 17/188 (9%)
Query: 99 TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW 158
T +D VF L+ I D++ F+ G++ D R++ D + +SKG +V F +
Sbjct: 146 TPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVS 205
Query: 159 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC 218
AI G + LG P +++ + + + + S +Y
Sbjct: 206 SVPLAIGLTGQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYV 254
Query: 219 GGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGT 272
G + +TE ++R F PFG+I I++ D KGY F+ F+ E A A+ +NG
Sbjct: 255 GSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGF 314
Query: 273 TIEGHVVK 280
+ G +K
Sbjct: 315 ELAGRPMK 322
>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
Length = 530
Score = 79.7 bits (195), Expect = 4e-15
Identities = 50/194 (25%), Positives = 101/194 (52%), Gaps = 8/194 (4%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF +
Sbjct: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
Query: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR-SQDHFHVFVGDLSPEIT 118
A+ + G++++G + V S +K+ +++ + Q+ S ++VG L IT
Sbjct: 208 PLAIG-LTGQRVLGVPIIVQ----ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNIT 262
Query: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178
+ ++ F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++
Sbjct: 263 EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
Query: 179 TNWATRKPPAPKST 192
T + A ++
Sbjct: 323 VGHVTERTDASSAS 336
Score = 72.0 bits (175), Expect = 8e-13
Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 17/188 (9%)
Query: 99 TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW 158
T +D VF L+ I D++ F+ G++ D R++ D + +SKG +V F +
Sbjct: 146 TPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVS 205
Query: 159 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC 218
AI G + LG P +++ + + + + S +Y
Sbjct: 206 SVPLAIGLTGQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYV 254
Query: 219 GGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGT 272
G + +TE ++R F PFG+I I++ D KGY F+ F+ E A A+ +NG
Sbjct: 255 GSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGF 314
Query: 273 TIEGHVVK 280
+ G +K
Sbjct: 315 ELAGRPMK 322
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 78.6 bits (192), Expect = 9e-15
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 24/168 (14%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
++VGDL PE+T + F+P G I R+ +D T +S GY +V++ DA+ A++ +
Sbjct: 4 LYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETL 63
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
+ GR +R W+ R P KS + V+ + +
Sbjct: 64 NFDVIKGRPVRIMWSQRDPSLRKSGVGN--------------------VFIKNLGKTIDN 103
Query: 228 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNG 271
+ + FS FG I+ +V D KGY FV F ESA AI +NG
Sbjct: 104 KALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNG 151
Score = 75.9 bits (185), Expect = 6e-14
Identities = 59/208 (28%), Positives = 92/208 (44%), Gaps = 31/208 (14%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L +VTEA++ + FS GP + ++ D T + Y +V + + A AL
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
+N I G+ V++ W+ S +K +VF+ +L I + +
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVG-------------NVFIKNLGKTIDNKALYNI 109
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI-------- 177
F+ FG I +V D KGYGFV F + AE AI M G +L R+I
Sbjct: 110 FSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSH 167
Query: 178 ------RTNWATRKPPAPKSTYESNTKQ 199
R WA + A +E +T +
Sbjct: 168 KEREAERGAWARQSTSADVKDFEEDTDE 195
Score = 45.4 bits (106), Expect = 8e-05
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 215 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 268
++Y G + +TE ++ + FSP G I+ IR+ DK GY++V + A A+ +
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 269 VNGTTIEGHVVKCYWGK 285
+N I+G V+ W +
Sbjct: 63 LNFDVIKGRPVRIMWSQ 79
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 78.6 bits (192), Expect = 9e-15
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 24/168 (14%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
++VGDL PE+T + F+P G I R+ +D T +S GY +V++ DA+ A++ +
Sbjct: 4 LYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETL 63
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
+ GR +R W+ R P KS + V+ + +
Sbjct: 64 NFDVIKGRPVRIMWSQRDPSLRKSGVGN--------------------VFIKNLGKTIDN 103
Query: 228 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNG 271
+ + FS FG I+ +V D KGY FV F ESA AI +NG
Sbjct: 104 KALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNG 151
Score = 75.9 bits (185), Expect = 6e-14
Identities = 59/208 (28%), Positives = 92/208 (44%), Gaps = 31/208 (14%)
Query: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
+LYVG+L +VTEA++ + FS GP + ++ D T + Y +V + + A AL
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
+N I G+ V++ W+ S +K +VF+ +L I + +
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVG-------------NVFIKNLGKTIDNKALYNI 109
Query: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQI-------- 177
F+ FG I +V D KGYGFV F + AE AI M G +L R+I
Sbjct: 110 FSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSH 167
Query: 178 ------RTNWATRKPPAPKSTYESNTKQ 199
R WA + A +E +T +
Sbjct: 168 KEREAERGAWARQSTSADVKDFEEDTDE 195
Score = 45.4 bits (106), Expect = 8e-05
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 215 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 268
++Y G + +TE ++ + FSP G I+ IR+ DK GY++V + A A+ +
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 269 VNGTTIEGHVVKCYWGK 285
+N I+G V+ W +
Sbjct: 63 LNFDVIKGRPVRIMWSQ 79
>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
Length = 405
Score = 75.9 bits (185), Expect = 6e-14
Identities = 49/187 (26%), Positives = 96/187 (51%), Gaps = 8/187 (4%)
Query: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E +
Sbjct: 127 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 186
Query: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDH-FHVFVGDLSPEIT 118
A+ + G++++G + V S +K+ ++ + Q+ ++VG L IT
Sbjct: 187 PLAIG-LTGQRLLGVPIIVQ----ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNIT 241
Query: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178
+ ++ F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R
Sbjct: 242 EDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 301
Query: 179 TNWATRK 185
T +
Sbjct: 302 VGHVTER 308
Score = 67.8 bits (164), Expect = 2e-11
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI
Sbjct: 134 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 193
Query: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
G + LG P +++ + + + + + +Y G + +TE
Sbjct: 194 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 242
Query: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 281
++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++
Sbjct: 243 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 302
Query: 282 YWGKETLD 289
E LD
Sbjct: 303 GHVTERLD 310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,589,886
Number of Sequences: 37866
Number of extensions: 694148
Number of successful extensions: 3329
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 258
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 1782
Number of HSP's gapped (non-prelim): 1002
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.