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Search of human proteins with 11321565
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11321565 matrilin 3 precursor [Homo sapiens]
(486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11321565 matrilin 3 precursor [Homo sapiens] 1005 0.0
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 363 e-100
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 363 e-100
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens] 311 8e-85
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 276 3e-74
gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens] 273 2e-73
gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens] 232 5e-61
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 132 9e-31
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 130 3e-30
gi|10190748 CEGP1 protein [Homo sapiens] 128 1e-29
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 125 9e-29
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 124 2e-28
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 121 2e-27
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 121 2e-27
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 119 6e-27
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 119 6e-27
gi|19743803 fibulin 5 precursor [Homo sapiens] 116 4e-26
gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa... 115 7e-26
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 108 1e-23
gi|56237021 fibrillin 3 precursor [Homo sapiens] 108 1e-23
gi|24430141 fibrillin 1 precursor [Homo sapiens] 108 1e-23
gi|66346695 fibrillin 2 precursor [Homo sapiens] 106 5e-23
gi|148886654 polydom [Homo sapiens] 101 2e-21
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 100 3e-21
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 100 3e-21
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 100 3e-21
gi|21359974 vitrin [Homo sapiens] 100 5e-21
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 99 1e-20
gi|46249414 latent transforming growth factor beta binding prote... 98 1e-20
gi|46249412 latent transforming growth factor beta binding prote... 98 1e-20
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 1005 bits (2599), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MPRPAPARRLPGLLLLLWPLLLLPSAAPDPVARPGFRRLETRGPGGSPGRRPSPAAPDGA 60
MPRPAPARRLPGLLLLLWPLLLLPSAAPDPVARPGFRRLETRGPGGSPGRRPSPAAPDGA
Sbjct: 1 MPRPAPARRLPGLLLLLWPLLLLPSAAPDPVARPGFRRLETRGPGGSPGRRPSPAAPDGA 60
Query: 61 PASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADT 120
PASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADT
Sbjct: 61 PASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADT 120
Query: 121 RVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGA 180
RVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGA
Sbjct: 121 RVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGA 180
Query: 181 REPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEE 240
REPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEE
Sbjct: 181 REPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEE 240
Query: 241 HVFYVETYGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNAD 300
HVFYVETYGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNAD
Sbjct: 241 HVFYVETYGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNAD 300
Query: 301 KKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ 360
KKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ
Sbjct: 301 KKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQ 360
Query: 361 HICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 420
HICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG
Sbjct: 361 HICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 420
Query: 421 YTLNEDKKTCSATEEARRLVSTEDACGCEATLAFQDKVSSYLQRLNTKLDDILEKLKINE 480
YTLNEDKKTCSATEEARRLVSTEDACGCEATLAFQDKVSSYLQRLNTKLDDILEKLKINE
Sbjct: 421 YTLNEDKKTCSATEEARRLVSTEDACGCEATLAFQDKVSSYLQRLNTKLDDILEKLKINE 480
Query: 481 YGQIHR 486
YGQIHR
Sbjct: 481 YGQIHR 486
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 363 bits (932), Expect = e-100
Identities = 196/417 (47%), Positives = 254/417 (60%), Gaps = 26/417 (6%)
Query: 14 LLLLWPLLLLPSAAPDPVARPGFRRLETRGPGGSPGRRPSPAAPDGAPASGTSEPGRARG 73
LL+L ++LLP+ A R +RG S GR + P A
Sbjct: 10 LLILGQIVLLPAEA----------RERSRGRSISRGRH------------ARTHPQTALL 47
Query: 74 AGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKI 133
C+++ DLVFIIDSSRSV ++ KVK F+ I+ LDIGP TRV ++ Y STVK
Sbjct: 48 ESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKN 107
Query: 134 EFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAII 193
EF L+ + K +++AV R+ LSTGTM+GLAIQ A++ AF+ GAR N+P+V +I
Sbjct: 108 EFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMI 167
Query: 194 VTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEK 253
VTDGRPQD V EVAA+A+ +GI ++A+GV + D +LK + SEP E+HVF V + IE
Sbjct: 168 VTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIET 227
Query: 254 LSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
L+S FQ+ C C H C H CI+ G + C C QGY LN+D+ TC D CA+
Sbjct: 228 LTSVFQKKLCTAHMCSTLEHNCAHFCINI-PGSYVCRCKQGYILNSDQTTCRIQDLCAME 286
Query: 314 THGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHC 373
H CE +CVN GS+ C+CY GY L ED K C A D CA HGC+H CVN GS+ C
Sbjct: 287 DHNCEQLCVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVN-ADGSYLC 344
Query: 374 ECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
+C+EG+ LN DKKTC+ D CA +HGCQH CV+ SY C C G+TLN DKKTC
Sbjct: 345 QCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTD-DSYSCHCLKGFTLNPDKKTC 400
Score = 173 bits (438), Expect = 4e-43
Identities = 94/247 (38%), Positives = 124/247 (50%), Gaps = 55/247 (22%)
Query: 259 QETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCE 318
++T +D C H CQH C++ + + C C +G+TLN DKKTC ++ CALN GCE
Sbjct: 356 KKTCTKIDYCASSNHGCQHECVNTDDS-YSCHCLKGFTLNPDKKTCRRINYCALNKPGCE 414
Query: 319 HICVNDRSGSYHCECYEGYTL--------------------------------------- 339
H CVN SY+C C+ GYTL
Sbjct: 415 HECVN-MEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 473
Query: 340 --NEDRKTCSAQDKCALGTHGCQHICVN-DRTGSHHCECYEGYTLNADKKTCSVRDKCAL 396
NED KTCS D C L HGC++ CVN DR S C+C EG+ L +D KTC+ D CAL
Sbjct: 474 LINEDLKTCSRVDYCLLSDHGCEYSCVNMDR--SFACQCPEGHVLRSDGKTCAKLDSCAL 531
Query: 397 GSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRL--------VSTEDACGC 448
G HGC+H CVS S+ C C+ GY L ED KTC + + + V+++D+ C
Sbjct: 532 GDHGCEHSCVS-SEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTC 590
Query: 449 EATLAFQ 455
E F+
Sbjct: 591 ECLEGFR 597
Score = 171 bits (432), Expect = 2e-42
Identities = 79/176 (44%), Positives = 106/176 (60%), Gaps = 4/176 (2%)
Query: 260 ETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH 319
+T +D C+L H C++ C++ + C+C +G+ L +D KTC+ LD CAL HGCEH
Sbjct: 480 KTCSRVDYCLLSDHGCEYSCVNM-DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH 538
Query: 320 ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGY 379
CV+ S+ C+C+EGY L ED KTC +D C HGC+HICVN S+ CEC EG+
Sbjct: 539 SCVSSED-SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNS-DDSYTCECLEGF 596
Query: 380 TLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
L D K C +D C HGC+HICV++G SY C C G+ L ED + C E
Sbjct: 597 RLAEDGKRCRRKDVCKSTHHGCEHICVNNG-NSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 154 bits (389), Expect = 2e-37
Identities = 75/187 (40%), Positives = 121/187 (64%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C P+DLVF+ID S+S+ F VK FV+ IID+L I P RV ++ Y++ V EF
Sbjct: 649 CTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFT 708
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L+ + + +K+AV + + G+M+GLA++ + +FT GAR S+ +P+ AI+ TD
Sbjct: 709 LRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTD 768
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GR QD V+E A++A+A+GI +YAVGV +A L+ +ASEP +H+FY E + ++++S
Sbjct: 769 GRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISE 828
Query: 257 RFQETFC 263
+ ++ C
Sbjct: 829 KLKKGIC 835
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 363 bits (932), Expect = e-100
Identities = 196/417 (47%), Positives = 254/417 (60%), Gaps = 26/417 (6%)
Query: 14 LLLLWPLLLLPSAAPDPVARPGFRRLETRGPGGSPGRRPSPAAPDGAPASGTSEPGRARG 73
LL+L ++LLP+ A R +RG S GR + P A
Sbjct: 10 LLILGQIVLLPAEA----------RERSRGRSISRGRH------------ARTHPQTALL 47
Query: 74 AGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKI 133
C+++ DLVFIIDSSRSV ++ KVK F+ I+ LDIGP TRV ++ Y STVK
Sbjct: 48 ESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKN 107
Query: 134 EFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAII 193
EF L+ + K +++AV R+ LSTGTM+GLAIQ A++ AF+ GAR N+P+V +I
Sbjct: 108 EFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMI 167
Query: 194 VTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEK 253
VTDGRPQD V EVAA+A+ +GI ++A+GV + D +LK + SEP E+HVF V + IE
Sbjct: 168 VTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIET 227
Query: 254 LSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
L+S FQ+ C C H C H CI+ G + C C QGY LN+D+ TC D CA+
Sbjct: 228 LTSVFQKKLCTAHMCSTLEHNCAHFCINI-PGSYVCRCKQGYILNSDQTTCRIQDLCAME 286
Query: 314 THGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHC 373
H CE +CVN GS+ C+CY GY L ED K C A D CA HGC+H CVN GS+ C
Sbjct: 287 DHNCEQLCVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVN-ADGSYLC 344
Query: 374 ECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
+C+EG+ LN DKKTC+ D CA +HGCQH CV+ SY C C G+TLN DKKTC
Sbjct: 345 QCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTD-DSYSCHCLKGFTLNPDKKTC 400
Score = 173 bits (438), Expect = 4e-43
Identities = 94/247 (38%), Positives = 124/247 (50%), Gaps = 55/247 (22%)
Query: 259 QETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCE 318
++T +D C H CQH C++ + + C C +G+TLN DKKTC ++ CALN GCE
Sbjct: 356 KKTCTKIDYCASSNHGCQHECVNTDDS-YSCHCLKGFTLNPDKKTCRRINYCALNKPGCE 414
Query: 319 HICVNDRSGSYHCECYEGYTL--------------------------------------- 339
H CVN SY+C C+ GYTL
Sbjct: 415 HECVN-MEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGF 473
Query: 340 --NEDRKTCSAQDKCALGTHGCQHICVN-DRTGSHHCECYEGYTLNADKKTCSVRDKCAL 396
NED KTCS D C L HGC++ CVN DR S C+C EG+ L +D KTC+ D CAL
Sbjct: 474 LINEDLKTCSRVDYCLLSDHGCEYSCVNMDR--SFACQCPEGHVLRSDGKTCAKLDSCAL 531
Query: 397 GSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRL--------VSTEDACGC 448
G HGC+H CVS S+ C C+ GY L ED KTC + + + V+++D+ C
Sbjct: 532 GDHGCEHSCVS-SEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTC 590
Query: 449 EATLAFQ 455
E F+
Sbjct: 591 ECLEGFR 597
Score = 171 bits (432), Expect = 2e-42
Identities = 79/176 (44%), Positives = 106/176 (60%), Gaps = 4/176 (2%)
Query: 260 ETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH 319
+T +D C+L H C++ C++ + C+C +G+ L +D KTC+ LD CAL HGCEH
Sbjct: 480 KTCSRVDYCLLSDHGCEYSCVNM-DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH 538
Query: 320 ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGY 379
CV+ S+ C+C+EGY L ED KTC +D C HGC+HICVN S+ CEC EG+
Sbjct: 539 SCVSSED-SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNS-DDSYTCECLEGF 596
Query: 380 TLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
L D K C +D C HGC+HICV++G SY C C G+ L ED + C E
Sbjct: 597 RLAEDGKRCRRKDVCKSTHHGCEHICVNNG-NSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 154 bits (389), Expect = 2e-37
Identities = 75/187 (40%), Positives = 121/187 (64%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C P+DLVF+ID S+S+ F VK FV+ IID+L I P RV ++ Y++ V EF
Sbjct: 649 CTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFT 708
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L+ + + +K+AV + + G+M+GLA++ + +FT GAR S+ +P+ AI+ TD
Sbjct: 709 LRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTD 768
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GR QD V+E A++A+A+GI +YAVGV +A L+ +ASEP +H+FY E + ++++S
Sbjct: 769 GRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISE 828
Query: 257 RFQETFC 263
+ ++ C
Sbjct: 829 KLKKGIC 835
>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
Length = 581
Score = 311 bits (797), Expect = 8e-85
Identities = 148/313 (47%), Positives = 213/313 (68%), Gaps = 3/313 (0%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C + PLDLVF+IDSSRSVRP EF ++ F+ ++ L++GP TRV V+ Y+S V+ F
Sbjct: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L+A++ ++ +++A+ + PL+ GTM+GLAIQ AM+ AF+V GAR P +P+VA+IVTD
Sbjct: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GRPQD+V EVAA+A+A GIE+YAVGV RAD+ SL+ MAS PL+EHVF VE++ +I++
Sbjct: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
Query: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHG 316
+FQ CA+D C GTH C+H C+ + G + C C G+ L D+++C A+D C+ H
Sbjct: 208 QFQSRLCAIDLCAEGTHGCEHHCV-NSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHS 266
Query: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECY 376
C+H CV+ G C C EG+ L D ++C +D C HGC+ CV++ S+ C C
Sbjct: 267 CQHECVSTPGGP-RCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGL-SYRCLCP 324
Query: 377 EGYTLNADKKTCS 389
EG L AD K+C+
Sbjct: 325 EGRQLQADGKSCN 337
Score = 158 bits (400), Expect = 9e-39
Identities = 89/237 (37%), Positives = 133/237 (56%), Gaps = 13/237 (5%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C+ +DLV ++D S+SVRP F VK FV++I+D LD+ P TRV +V ++S V+ EF
Sbjct: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L Y +KQAV + + GTM+GLA++ ++ +F+ GAR + N+P+V ++ TD
Sbjct: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GR QD ++ AARA+ GI +YAVGV +A A L+ +ASEP E HV Y +G + L
Sbjct: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 518
Query: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
+ + C + GT E + CEC + +T AL+ LN
Sbjct: 519 NLRGSICPEEGISAGT-----------ELRSPCECES--LVEFQGRTLGALESLTLN 562
Score = 84.0 bits (206), Expect = 3e-16
Identities = 43/102 (42%), Positives = 56/102 (54%), Gaps = 7/102 (6%)
Query: 348 AQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
A D CA GTHGC+H CVN GS+ C C G+ L D+++C D C+ G+H CQH CVS
Sbjct: 215 AIDLCAEGTHGCEHHCVNS-PGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVS 273
Query: 408 DGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACGCE 449
C C G+ L D ++C + R L + D GCE
Sbjct: 274 TPGGP-RCHCREGHDLQPDGRSC----QVRDLCNGVDH-GCE 309
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 276 bits (706), Expect = 3e-74
Identities = 137/231 (59%), Positives = 177/231 (76%), Gaps = 2/231 (0%)
Query: 76 VCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEF 135
+C++RP DLVF++DSSRSVRP+EF KVK F+S++I++LD+GP TRV +VNYASTVK EF
Sbjct: 34 LCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMVNYASTVKQEF 93
Query: 136 QLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVT 195
L+A+ K +L QAV RI PLSTGTM+GLAIQ A+ +AF G R S +I KV I+VT
Sbjct: 94 SLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRSPDISKVVIVVT 153
Query: 196 DGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLS 255
DGRPQD V +V+ARA+ASG+EL+A+GV D A+L+ +ASEP +EHV YVE+Y VIEKLS
Sbjct: 154 DGRPQDSVQDVSARARASGVELFAIGVGSVDKATLRQIASEPQDEHVDYVESYSVIEKLS 213
Query: 256 SRFQETFCAL-DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCS 305
+FQE FC + D C G H C+ VCIS G + C C +G+TLN+D KTC+
Sbjct: 214 RKFQEAFCVVSDLCATGDHDCEQVCIS-SPGSYTCACHEGFTLNSDGKTCN 263
Score = 150 bits (378), Expect = 3e-36
Identities = 79/191 (41%), Positives = 119/191 (62%), Gaps = 4/191 (2%)
Query: 79 SRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQ 138
S DLVF+ID S+SVRP F VK F+S+I+DTLD+ +V +V Y+S+V+ EF L
Sbjct: 271 SSATDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLG 330
Query: 139 AYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGR 198
+ K+ +K AV ++ + GTM+G A++ +D +FTV +GAR + KV I+ TDGR
Sbjct: 331 RFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQ---KVGIVFTDGR 387
Query: 199 PQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRF 258
QD +N+ A +A+ G +++AVGV A L+ +ASEP+ EH FY + I ++ +
Sbjct: 388 SQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKL 447
Query: 259 QETFCA-LDPC 268
Q+ C DPC
Sbjct: 448 QKKICVEEDPC 458
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
Query: 330 HCECYEGYTLNE------DRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNA 383
H + E Y++ E C D CA G H C+ +C++ GS+ C C+EG+TLN+
Sbjct: 199 HVDYVESYSVIEKLSRKFQEAFCVVSDLCATGDHDCEQVCISS-PGSYTCACHEGFTLNS 257
Query: 384 DKKTCSVRDKCALGSHGCQHICVSDGAAS 412
D KTC+V GS + + DG+ S
Sbjct: 258 DGKTCNVCSGGG-GSSATDLVFLIDGSKS 285
Score = 54.7 bits (130), Expect = 2e-07
Identities = 22/44 (50%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 388 CSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCS 431
C V D CA G H C+ +C+S SY C C+ G+TLN D KTC+
Sbjct: 221 CVVSDLCATGDHDCEQVCISS-PGSYTCACHEGFTLNSDGKTCN 263
Score = 37.4 bits (85), Expect = 0.031
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 437 RRLVSTEDACGCEATLAFQDKVSSYLQRLNTKLDDILEKLKINE 480
+++ ED C CE+ + FQ KV LQ L KL+ + ++L I E
Sbjct: 449 KKICVEEDPCACESLVKFQAKVEGLLQALTRKLEAVSKRLAILE 492
>gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
Length = 540
Score = 273 bits (699), Expect = 2e-73
Identities = 134/271 (49%), Positives = 186/271 (68%), Gaps = 2/271 (0%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C + PLDLVF+IDSSRSVRP EF ++ F+ ++ L++GP TRV V+ Y+S V+ F
Sbjct: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L+A++ ++ +++A+ + PL+ GTM+GLAIQ AM+ AF+V GAR P +P+VA+IVTD
Sbjct: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GRPQD+V EVAA+A+A GIE+YAVGV RAD+ SL+ MAS PL+EHVF VE++ +I++
Sbjct: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
Query: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHG 316
+FQ CA+D C G H CQH C+S G C C +G+ L D ++C D C HG
Sbjct: 208 QFQSRLCAIDYCSFGNHSCQHECVST-PGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHG 266
Query: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTCS 347
CE CV++ SY C C EG L D K+C+
Sbjct: 267 CEFQCVSE-GLSYRCLCPEGRQLQADGKSCN 296
Score = 158 bits (400), Expect = 9e-39
Identities = 89/237 (37%), Positives = 133/237 (56%), Gaps = 13/237 (5%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C+ +DLV ++D S+SVRP F VK FV++I+D LD+ P TRV +V ++S V+ EF
Sbjct: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L Y +KQAV + + GTM+GLA++ ++ +F+ GAR + N+P+V ++ TD
Sbjct: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GR QD ++ AARA+ GI +YAVGV +A A L+ +ASEP E HV Y +G + L
Sbjct: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 477
Query: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
+ + C + GT E + CEC + +T AL+ LN
Sbjct: 478 NLRGSICPEEGISAGT-----------ELRSPCECES--LVEFQGRTLGALESLTLN 521
Score = 79.7 bits (195), Expect = 5e-15
Identities = 39/88 (44%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Query: 348 AQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
A D C+ G H CQH CV+ G C C EG+ L D ++C VRD C HGC+ CVS
Sbjct: 215 AIDYCSFGNHSCQHECVST-PGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVS 273
Query: 408 DGAASYHCDCYPGYTLNEDKKTCSATEE 435
+G SY C C G L D K+C+ E
Sbjct: 274 EG-LSYRCLCPEGRQLQADGKSCNRCRE 300
>gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
Length = 499
Score = 232 bits (592), Expect = 5e-61
Identities = 114/229 (49%), Positives = 163/229 (71%), Gaps = 1/229 (0%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C + PLDLVF+IDSSRSVRP EF ++ F+ ++ L++GP TRV V+ Y+S V+ F
Sbjct: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L+A++ ++ +++A+ + PL+ GTM+GLAIQ AM+ AF+V GAR P +P+VA+IVTD
Sbjct: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GRPQD+V EVAA+A+A GIE+YAVGV RAD+ SL+ MAS PL+EHVF VE++ +I++
Sbjct: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
Query: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCS 305
+FQ C D C H C+ C+S+G + C C +G L AD K+C+
Sbjct: 208 QFQSRLCVRDLCNGVDHGCEFQCVSEGL-SYRCLCPEGRQLQADGKSCN 255
Score = 158 bits (400), Expect = 9e-39
Identities = 89/237 (37%), Positives = 133/237 (56%), Gaps = 13/237 (5%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C+ +DLV ++D S+SVRP F VK FV++I+D LD+ P TRV +V ++S V+ EF
Sbjct: 257 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 316
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L Y +KQAV + + GTM+GLA++ ++ +F+ GAR + N+P+V ++ TD
Sbjct: 317 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 376
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
GR QD ++ AARA+ GI +YAVGV +A A L+ +ASEP E HV Y +G + L
Sbjct: 377 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 436
Query: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
+ + C + GT E + CEC + +T AL+ LN
Sbjct: 437 NLRGSICPEEGISAGT-----------ELRSPCECES--LVEFQGRTLGALESLTLN 480
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 379 YTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
+ L + C VRD C HGC+ CVS+G SY C C G L D K+C+ E
Sbjct: 205 FGLQFQSRLC-VRDLCNGVDHGCEFQCVSEG-LSYRCLCPEGRQLQADGKSCNRCRE 259
Score = 35.4 bits (80), Expect = 0.12
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 349 QDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCS 389
+D C HGC+ CV++ S+ C C EG L AD K+C+
Sbjct: 216 RDLCNGVDHGCEFQCVSEGL-SYRCLCPEGRQLQADGKSCN 255
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 132 bits (331), Expect = 9e-31
Identities = 68/176 (38%), Positives = 93/176 (52%), Gaps = 10/176 (5%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDR-----CALNTHGCEH 319
+D C G QC H C++ +G C C GY L AD + C ++ C N GC H
Sbjct: 286 VDECAAGLAQCAHGCLNT-QGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 344
Query: 320 ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGY 379
C + +G C C GY L+ D++TC D CA + CQ +C N+ G + C CY GY
Sbjct: 345 GCSHTSAGPL-CTCPRGYELDTDQRTCIDVDDCA-DSPCCQQVCTNN-PGGYECGCYAGY 401
Query: 380 TLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
L+AD C D+CA GC+H C ++ A S+ C C GY L+ED++ CS EE
Sbjct: 402 RLSADGCGCEDVDECASSRGGCEHHC-TNLAGSFQCSCEAGYRLHEDRRGCSPLEE 456
Score = 130 bits (327), Expect = 3e-30
Identities = 68/179 (37%), Positives = 89/179 (49%), Gaps = 5/179 (2%)
Query: 258 FQETFCALDPCVLGTHQ--CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTH 315
FQ C D TH CQH C++ G + CEC G+ L+ D +TC A++ CAL
Sbjct: 153 FQGPRCQYDVDECRTHNGGCQHRCVNT-PGSYLCECKPGFRLHTDSRTCLAINSCALGNG 211
Query: 316 GCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCEC 375
GC+H CV + C+C G+ L ED + C + CA C H C R G CEC
Sbjct: 212 GCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVR-GLARCEC 270
Query: 376 YEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATE 434
+ GY L AD K C D+CA G C H C++ S+ C C+ GY L D + C E
Sbjct: 271 HVGYQLAADGKACEDVDECAAGLAQCAHGCLNT-QGSFKCVCHAGYELGADGRQCYRIE 328
Score = 123 bits (309), Expect = 3e-28
Identities = 66/191 (34%), Positives = 89/191 (46%), Gaps = 8/191 (4%)
Query: 261 TFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHI 320
T A++ C LG CQH C+ +H C+C G+ L D + C CA C H
Sbjct: 199 TCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHR 258
Query: 321 CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYT 380
C R G CEC+ GY L D K C D+CA G C H C+N + GS C C+ GY
Sbjct: 259 CQVVR-GLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQ-GSFKCVCHAGYE 316
Query: 381 LNADKKTC-----SVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
L AD + C + + C + GC H C S +A C C GY L+ D++TC ++
Sbjct: 317 LGADGRQCYRIEMEIVNSCEANNGGCSHGC-SHTSAGPLCTCPRGYELDTDQRTCIDVDD 375
Query: 436 ARRLVSTEDAC 446
+ C
Sbjct: 376 CADSPCCQQVC 386
Score = 111 bits (277), Expect = 2e-24
Identities = 58/148 (39%), Positives = 74/148 (50%), Gaps = 7/148 (4%)
Query: 289 CECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSA 348
C C G+ + +D C + GC+H CVN GSY CEC G+ L+ D +TC A
Sbjct: 147 CHCPPGFQ---GPRCQYDVDECRTHNGGCQHRCVNT-PGSYLCECKPGFRLHTDSRTCLA 202
Query: 349 QDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHIC-VS 407
+ CALG GCQH CV H C+C G+ L D + C R CA + C H C V
Sbjct: 203 INSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVV 262
Query: 408 DGAASYHCDCYPGYTLNEDKKTCSATEE 435
G A C+C+ GY L D K C +E
Sbjct: 263 RGLA--RCECHVGYQLAADGKACEDVDE 288
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/189 (26%), Positives = 74/189 (39%), Gaps = 45/189 (23%)
Query: 275 CQHVCISDGEG---KHHCECSQGYTLNADKKTC---------SALDRCALNTHGCEHICV 322
C+H C + G + C C+ G +A +C + C +T+G H C
Sbjct: 943 CEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG--HNC- 999
Query: 323 NDRSGSYHCECYEGYTLNEDRKTC---------SAQDKCALGTHG--CQHICVNDRTG-- 369
S C C+ G + + C S C G +G C+H C+ G
Sbjct: 1000 -----SQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC 1054
Query: 370 ---SHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI--CVSDGAASYH---CDCYPGY 421
S HC C EG+ A +K C RD A GC+H C++ G H C C G+
Sbjct: 1055 DPVSGHCACPEGWAGLACEKECLPRDVRA----GCRHSGGCLNGGLCDPHTGRCLCPAGW 1110
Query: 422 TLNEDKKTC 430
T ++ + C
Sbjct: 1111 TGDKCQSPC 1119
Score = 43.9 bits (102), Expect = 3e-04
Identities = 46/165 (27%), Positives = 59/165 (35%), Gaps = 30/165 (18%)
Query: 274 QCQHVCISDGEG---KHHCECSQGYTLNADKKTCSALDRCALNTHG--CEHICVNDRSGS 328
+C+ C + G +H C C G +A +CS C L G CE C R G+
Sbjct: 1287 RCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCS----CGLGWTGRHCELACPPGRYGA 1342
Query: 329 ---YHCECYEGYTLNEDRKTCSAQDKCALGTHG--CQHICVNDRTGS---HHCECYEGYT 380
C C+ T TC +C G +G C+H C G+ C C G
Sbjct: 1343 ACHLECSCHNNSTCEPATGTC----RCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG-- 1396
Query: 381 LNADKKTCSVRDKCALGSHG--CQHICVSDG---AASYHCDCYPG 420
A S R C G HG C+ C CDC G
Sbjct: 1397 --APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGG 1439
Score = 43.5 bits (101), Expect = 4e-04
Identities = 58/230 (25%), Positives = 84/230 (36%), Gaps = 52/230 (22%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHG-------C 317
+D C C+H C ++ G C C GY L+ D++ CS L+ ++ G
Sbjct: 413 VDECASSRGGCEHHC-TNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL 471
Query: 318 EHICV----------NDRSGS--YHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN 365
HI V +D G+ E +TL E K D H C C +
Sbjct: 472 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTE--KFVCLDDSFG---HDCSLTCDD 526
Query: 366 DRTGS------HHCECYEGYTLNADKKTC---SVRDKCALGSHGCQHICVSD-------- 408
R G C+C EG+T +TC + C+ S CQ+ D
Sbjct: 527 CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSF-SCSCQNGGTCDSVTGACRC 585
Query: 409 --GAASYHCD--CYPGYTLNEDKKTCSATEEAR--RLVSTEDACGCEATL 452
G + +C+ C GY +K C+ R RL AC C+ L
Sbjct: 586 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYG---ACLCDPGL 632
Score = 37.4 bits (85), Expect = 0.031
Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 37/152 (24%)
Query: 275 CQHVCISDGEGKH---HCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHC 331
C C D GK+ C C G T ++ C RC G +C
Sbjct: 551 CNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC----RCPPGVSGT------------NC 594
Query: 332 E--CYEGYTLNEDRKTCSAQDK-----------CALGTHG--CQHICVNDRTG---SHHC 373
E C +GY RK C+ ++ C G +G C C G S C
Sbjct: 595 EDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEEC 654
Query: 374 ECYEGYTLNADKKTCSVRDKCALGSHGCQHIC 405
+C + +T + DK+ S K CQ C
Sbjct: 655 QCVQPHTQSCDKRDGSCSCKAGFRGERCQAEC 686
Score = 35.8 bits (81), Expect = 0.090
Identities = 43/169 (25%), Positives = 66/169 (39%), Gaps = 33/169 (19%)
Query: 274 QCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCEC 333
+C C + +G+ +C Q + CS+ C+ C + + C C
Sbjct: 713 ECGKRCPAGFQGE---DCGQECPVGTFGVNCSS--SCSCGGAPCHGV-------TGQCRC 760
Query: 334 YEGYTLNEDRKTCSAQDKCALGTH----GCQHICVND-RTGSHHCECYEGYTLNADKKTC 388
G T ED + + + LG CQH D TG+ C C G+ +
Sbjct: 761 PPGRT-GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSR----- 812
Query: 389 SVRDKCALGSHG--CQH--ICVSDG---AASYHCDCYPGYTLNEDKKTC 430
+D C G +G CQ C +DG A+ HC C PG+T ++ C
Sbjct: 813 -CQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRAC 860
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 130 bits (326), Expect = 3e-30
Identities = 72/194 (37%), Positives = 112/194 (57%), Gaps = 1/194 (0%)
Query: 70 RARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYAS 129
+A+ AG CKS DLVF++D+S SV +F KV+ +V+ ++DT ++GP TRV VV Y+
Sbjct: 26 QAQRAG-CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSD 84
Query: 130 TVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPK 189
F+L + ++ +K A R+ T +G A++ +F+ AG R +
Sbjct: 85 RPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQ 144
Query: 190 VAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYG 249
VAI++TDGR QD V + AA A +GI ++AVGV A L+ +ASEP HVF+V +
Sbjct: 145 VAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFN 204
Query: 250 VIEKLSSRFQETFC 263
I+K+ + + C
Sbjct: 205 AIDKIRGKLRRRLC 218
Score = 30.0 bits (66), Expect = 4.9
Identities = 27/80 (33%), Positives = 29/80 (36%), Gaps = 23/80 (28%)
Query: 10 LPGLLLLLWPLLLLPSAAPDPVARPGFRRLETRGPGGSPG--------RRPSPAAPDGAP 61
+PGLL L P P P PG GPGGSPG +P P P G P
Sbjct: 706 IPGLLGLQGP--------PGPPGVPG-----PPGPGGSPGLPGEIGFPGKPGPPGPTGPP 752
Query: 62 ASGTSEPGRARGAGVCKSRP 81
G P G K P
Sbjct: 753 --GKDGPNGPPGPPGTKGEP 770
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 128 bits (322), Expect = 1e-29
Identities = 62/166 (37%), Positives = 86/166 (51%), Gaps = 6/166 (3%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
++ C + C C G H C C G+TL D KTC +D C GC+H C N
Sbjct: 283 METCAVNNGGCDRTCKDTSTGVH-CSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKN- 340
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
GS+ C C +G+ L D K+C D+C+L C H C+N G+ C C GYTL
Sbjct: 341 IVGSFDCGCKKGFKLLTDEKSCQDVDECSL-DRTCDHSCIN-HPGTFACACNRGYTLYGF 398
Query: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
C ++C++ + GCQ +CV+ SY C C+PGY L+ +KK C
Sbjct: 399 TH-CGDTNECSINNGGCQQVCVNT-VGSYECQCHPGYKLHWNKKDC 442
Score = 110 bits (276), Expect = 2e-24
Identities = 58/175 (33%), Positives = 83/175 (47%), Gaps = 10/175 (5%)
Query: 265 LDPCVLGTHQCQHVCISDGEG-KHHCECSQGYTLNADKKTCSALDRCALNTHG-CEHICV 322
+D C G C + + C C GY + + C +D C +G C H C+
Sbjct: 46 VDECAQGLDDCHADALCQNTPTSYKCSCKPGY--QGEGRQCEDIDECGNELNGGCVHDCL 103
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
N G+Y C C++G+ L D C D+C GCQH CVN GS+ C C EG+ L+
Sbjct: 104 NI-PGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVN-VMGSYECCCKEGFFLS 161
Query: 383 ADKKTCSVRDK----CALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSAT 433
++ TC R + C HGC HIC S C+C PG+ L ++++ C T
Sbjct: 162 DNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILT 216
Score = 105 bits (262), Expect = 9e-23
Identities = 64/228 (28%), Positives = 95/228 (41%), Gaps = 49/228 (21%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDR----CALNTHGCEHI 320
+D C+ CQH C++ G + C C +G+ L+ ++ TC C HGC HI
Sbjct: 129 VDECLENNGGCQHTCVNV-MGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHI 187
Query: 321 CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYT 380
C GS CEC G+ L ++++ C C G GCQH C +D C C+ Y
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRDCILT--CNHGNGGCQHSC-DDTADGPECSCHPQYK 244
Query: 381 LNADKKTCSVRDK----------------------------CALGSHGCQHICVSDGAAS 412
++ D ++C R+ CA+ + GC C D +
Sbjct: 245 MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTC-KDTSTG 303
Query: 413 YHCDCYPGYTLNEDKKTCSATEE-----------ARRLVSTEDACGCE 449
HC C G+TL D KTC +E + +V + D CGC+
Sbjct: 304 VHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFD-CGCK 350
Score = 102 bits (253), Expect = 1e-21
Identities = 56/207 (27%), Positives = 87/207 (42%), Gaps = 33/207 (15%)
Query: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
C+ H C H+C G CEC G+ L +++ C + C GC+H C +D +
Sbjct: 177 CMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSC-DDTAD 233
Query: 328 SYHCECYEGYTLNEDRKTCSAQDK----------------------------CALGTHGC 359
C C+ Y ++ D ++C ++ CA+ GC
Sbjct: 234 GPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGC 293
Query: 360 QHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYP 419
C + TG H C C G+TL D KTC D+C + GC H C + S+ C C
Sbjct: 294 DRTCKDTSTGVH-CSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFC-KNIVGSFDCGCKK 351
Query: 420 GYTLNEDKKTCSATEEARRLVSTEDAC 446
G+ L D+K+C +E + + +C
Sbjct: 352 GFKLLTDEKSCQDVDECSLDRTCDHSC 378
Score = 47.4 bits (111), Expect = 3e-05
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 12/105 (11%)
Query: 350 DKCALGTHGCQH--ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHG-CQHICV 406
D+CA G C +C N T S+ C C GY + + C D+C +G C H C+
Sbjct: 47 DECAQGLDDCHADALCQNTPT-SYKCSCKPGY--QGEGRQCEDIDECGNELNGGCVHDCL 103
Query: 407 SDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACGCEAT 451
+ +Y C C+ G+ L D C +E E+ GC+ T
Sbjct: 104 NI-PGNYRCTCFDGFMLAHDGHNCLDVDEC-----LENNGGCQHT 142
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 125 bits (314), Expect = 9e-29
Identities = 67/189 (35%), Positives = 105/189 (55%), Gaps = 4/189 (2%)
Query: 76 VCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLD-IGPADTRVAVVNYASTVKIE 134
VCK+ DLVF++D S S+ F K+ +F+ + L+ IG T+VA+V + + E
Sbjct: 1025 VCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTE 1084
Query: 135 FQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIV 194
F+L AY K++L A+ I+ T +G AI+ D FT E+G R IPKV +++
Sbjct: 1085 FKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRR---GIPKVIVVI 1141
Query: 195 TDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKL 254
TDGR QD VN+++ Q G ++A+GV AD + L + S+P HVF+V+ + +K+
Sbjct: 1142 TDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKI 1201
Query: 255 SSRFQETFC 263
C
Sbjct: 1202 EDELITFVC 1210
Score = 114 bits (285), Expect = 2e-25
Identities = 62/215 (28%), Positives = 113/215 (52%), Gaps = 6/215 (2%)
Query: 51 RPSPAAPDGAPASGTSEPGRARGAGVCKSRPL-DLVFIIDSSRSVRPLEFTKVKTFVSRI 109
+P D S S P + VC++ + D+V ++D S S+ F V+ F+ +
Sbjct: 127 KPRVKVVDRGNGSRPSSPEEVKF--VCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENL 184
Query: 110 IDTLDIGPADTRVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTA 169
+ D+G TR+ + Y+ +IE+ L A++ K + +AV + T++GLA+
Sbjct: 185 VTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYI 244
Query: 170 MDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMAS 229
+ +F EAG+R + + K+ I++TDG+ QD + + + SG+EL+A+GV AD+
Sbjct: 245 FENSFKPEAGSR---TGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNE 301
Query: 230 LKMMASEPLEEHVFYVETYGVIEKLSSRFQETFCA 264
L+ +ASEP HV+ V + ++ + T C+
Sbjct: 302 LQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCS 336
Score = 32.7 bits (73), Expect = 0.76
Identities = 22/66 (33%), Positives = 24/66 (36%), Gaps = 10/66 (15%)
Query: 24 PSAAPDPVARPGFRRLETRGPGGSPGRR--------PSPAAPDGAPASGTSEPGRARGAG 75
P P P G R + GP GSPG R P P P G P G +P G
Sbjct: 1711 PRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQP--GYCDPSSCSAYG 1768
Query: 76 VCKSRP 81
V P
Sbjct: 1769 VRAPHP 1774
Score = 29.6 bits (65), Expect = 6.4
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 42 RGPGGSPGRRPSPAAPDGAPASGTSEPGRARGAGV 76
+GP G PGR SP AP GT PG AGV
Sbjct: 1653 QGPPGEPGRPGSPGAPGEQGPPGT--PGFPGNAGV 1685
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 124 bits (311), Expect = 2e-28
Identities = 66/190 (34%), Positives = 95/190 (50%), Gaps = 10/190 (5%)
Query: 250 VIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHH-CECSQGYTLNADKKTCSALD 308
++ ++++ + +D CV GT C I + + C C GYT D K C +D
Sbjct: 15 LVHARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVD 72
Query: 309 RCALNTH-GCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDR 367
C + GC H CVN G+Y C CY+G+ L D C D+CA G GCQ CVN
Sbjct: 73 ECEREDNAGCVHDCVNI-PGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVN-M 130
Query: 368 TGSHHCECYEGYTLNADKKTCSVRDK----CALGSHGCQHICVSDGAASYHCDCYPGYTL 423
GS+ C C EG+ L+ ++ TC R + C +HGC HIC C+C PG+ L
Sbjct: 131 MGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFEL 190
Query: 424 NEDKKTCSAT 433
++++ C T
Sbjct: 191 TKNQRDCKLT 200
Score = 115 bits (289), Expect = 7e-26
Identities = 60/177 (33%), Positives = 84/177 (47%), Gaps = 11/177 (6%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDR----CALNTHGCEHI 320
+D C G CQ C++ G + C C +G+ L+ ++ TC C HGC HI
Sbjct: 113 VDECAEGNGGCQQSCVNM-MGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHI 171
Query: 321 CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYT 380
C G CEC G+ L ++++ C C G GCQH C + G C C+ +
Sbjct: 172 CRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGCQHTCDDTEQGPR-CGCHIKFV 228
Query: 381 LNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEAR 437
L+ D KTC + CA+ + GC C D A HC C G+ L D+KTC +E R
Sbjct: 229 LHTDGKTCI--ETCAVNNGGCDSKC-HDAATGVHCTCPVGFMLQPDRKTCKDIDECR 282
Score = 113 bits (283), Expect = 3e-25
Identities = 57/168 (33%), Positives = 82/168 (48%), Gaps = 7/168 (4%)
Query: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
C+ H C H+C +G CEC G+ L +++ C C GC+H C + G
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGCQHTCDDTEQG 218
Query: 328 SYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKT 387
C C+ + L+ D KTC + CA+ GC C + TG H C C G+ L D+KT
Sbjct: 219 P-RCGCHIKFVLHTDGKTCI--ETCAVNNGGCDSKCHDAATGVH-CTCPVGFMLQPDRKT 274
Query: 388 CSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
C D+C L + GC HIC + S+ C C GY L +++ C +E
Sbjct: 275 CKDIDECRLNNGGCDHIC-RNTVGSFECSCKKGYKLLINERNCQDIDE 321
Score = 110 bits (276), Expect = 2e-24
Identities = 60/168 (35%), Positives = 83/168 (49%), Gaps = 7/168 (4%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
++ C + C C G H C C G+ L D+KTC +D C LN GC+HIC N
Sbjct: 237 IETCAVNNGGCDSKCHDAATGVH-CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRN- 294
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
GS+ C C +GY L + + C D+C+ C HICVN GS C C+ GY L
Sbjct: 295 TVGSFECSCKKGYKLLINERNCQDIDECSF-DRTCDHICVN-TPGSFQCLCHRGYLLYGI 352
Query: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY-TLNEDKKTCS 431
C D+C++ GC+ C++ SY C C G L+ + K C+
Sbjct: 353 TH-CGDVDECSINRGGCRFGCINT-PGSYQCTCPAGQGRLHWNGKDCT 398
Score = 52.0 bits (123), Expect = 1e-06
Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 344 KTCSAQDKCALGTHGCQ--HICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSH-G 400
K D+C GT C IC N S+ C C GYT D K C D+C + G
Sbjct: 25 KAAQDVDECVEGTDNCHIDAICQNTPR-SYKCICKSGYT--GDGKHCKDVDECEREDNAG 81
Query: 401 CQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
C H CV+ +Y C CY G+ L D C +E
Sbjct: 82 CVHDCVNI-PGNYRCTCYDGFHLAHDGHNCLDVDE 115
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 121 bits (303), Expect = 2e-27
Identities = 75/212 (35%), Positives = 105/212 (49%), Gaps = 8/212 (3%)
Query: 53 SPAAPDGAPASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDT 112
+P P P T P R VCK D+VF+ D+S S+ F KV F+ +
Sbjct: 1133 APTEPPTPPPPPTIPPAR----DVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGG 1188
Query: 113 LD-IGPADTRVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMD 171
D I PA +V+ V Y+ VK EF+L Y DK A+ I T +G A+ +
Sbjct: 1189 FDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKE 1248
Query: 172 EAFTVEAGAREPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLK 231
+ T E+G R+ N+PKV ++VTDGR QD+V + A Q SG ++ VGV D L
Sbjct: 1249 KVLTWESGMRK---NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELA 1305
Query: 232 MMASEPLEEHVFYVETYGVIEKLSSRFQETFC 263
+AS+P E HVF V+ + EK+ C
Sbjct: 1306 NIASKPSERHVFIVDDFESFEKIEDNLITFVC 1337
Score = 119 bits (299), Expect = 5e-27
Identities = 57/181 (31%), Positives = 103/181 (56%), Gaps = 3/181 (1%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
D+V ++D S S+ F V++F+SRI++ DIGP ++A+ Y+ + E+QL A+ D
Sbjct: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 94
Query: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
K+SL QAV + T++G+A+ + F +AG R + K+ +++TDG+ QD
Sbjct: 95 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRAR---KIGVLITDGKSQDD 151
Query: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQETF 262
V + + + G+EL+A+G+ AD LKM+A++P + H + V + + ++
Sbjct: 152 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 211
Query: 263 C 263
C
Sbjct: 212 C 212
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 121 bits (303), Expect = 2e-27
Identities = 75/212 (35%), Positives = 105/212 (49%), Gaps = 8/212 (3%)
Query: 53 SPAAPDGAPASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDT 112
+P P P T P R VCK D+VF+ D+S S+ F KV F+ +
Sbjct: 2297 APTEPPTPPPPPTIPPAR----DVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGG 2352
Query: 113 LD-IGPADTRVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMD 171
D I PA +V+ V Y+ VK EF+L Y DK A+ I T +G A+ +
Sbjct: 2353 FDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKE 2412
Query: 172 EAFTVEAGAREPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLK 231
+ T E+G R+ N+PKV ++VTDGR QD+V + A Q SG ++ VGV D L
Sbjct: 2413 KVLTWESGMRK---NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELA 2469
Query: 232 MMASEPLEEHVFYVETYGVIEKLSSRFQETFC 263
+AS+P E HVF V+ + EK+ C
Sbjct: 2470 NIASKPSERHVFIVDDFESFEKIEDNLITFVC 2501
Score = 119 bits (299), Expect = 5e-27
Identities = 70/198 (35%), Positives = 101/198 (51%), Gaps = 3/198 (1%)
Query: 67 EPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVN 126
+PG+ S DLVF++D S SV F + F++ ++ DIG TRV VV
Sbjct: 124 KPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQ 183
Query: 127 YASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSN 186
Y+S + EF L Y + L A+ +I TM+G AI + FT AGAR
Sbjct: 184 YSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGAR---VG 240
Query: 187 IPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVE 246
PKVAII+TDG+ QD+V A + G+E++++G+ AD LK +AS P HVF V
Sbjct: 241 FPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVA 300
Query: 247 TYGVIEKLSSRFQETFCA 264
+ I + + C+
Sbjct: 301 NFDAIVDIQNEIISQVCS 318
Score = 119 bits (299), Expect = 5e-27
Identities = 57/181 (31%), Positives = 103/181 (56%), Gaps = 3/181 (1%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
D+V ++D S S+ F V++F+SRI++ DIGP ++A+ Y+ + E+QL A+ D
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
K+SL QAV + T++G+A+ + F +AG R + K+ +++TDG+ QD
Sbjct: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRAR---KIGVLITDGKSQDD 1315
Query: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQETF 262
V + + + G+EL+A+G+ AD LKM+A++P + H + V + + ++
Sbjct: 1316 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 1375
Query: 263 C 263
C
Sbjct: 1376 C 1376
Score = 109 bits (272), Expect = 6e-24
Identities = 55/181 (30%), Positives = 100/181 (55%), Gaps = 3/181 (1%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
D+VF++D S S+ F KV+ F+ ++ + +I P ++++V Y+ EF L+ +T
Sbjct: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTK 499
Query: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
+ + +A+ T +G A+ ++ F G+R SN+PKV I++TDG+ D
Sbjct: 500 VEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSR---SNVPKVMILITDGKSSDA 556
Query: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQETF 262
+ A + + S +E++AVGV A + L+ +AS P E HVF VE + +++S ++
Sbjct: 557 FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616
Query: 263 C 263
C
Sbjct: 617 C 617
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 119 bits (298), Expect = 6e-27
Identities = 74/204 (36%), Positives = 108/204 (52%), Gaps = 9/204 (4%)
Query: 66 SEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVV 125
+E G R + C++ P DLVFI+D S SV P F VK ++ I DIGP +V VV
Sbjct: 22 AEDGEVRSS--CRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVV 79
Query: 126 NYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSS 185
Y+ +E L +Y + L AV I L T +G AIQ A+D F + S
Sbjct: 80 QYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFA------KSSR 133
Query: 186 NIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGV-DRADMASLKMMASEPLEEHVFY 244
+ K+A+++TDG+ QD V + A A+ S I L+A+GV + A L+ +A++P +VFY
Sbjct: 134 FLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFY 193
Query: 245 VETYGVIEKLSSRFQETFCALDPC 268
VE Y I K+ ++ C C
Sbjct: 194 VEDYIAISKIREVMKQKLCEESVC 217
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 119 bits (298), Expect = 6e-27
Identities = 67/204 (32%), Positives = 93/204 (45%), Gaps = 19/204 (9%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHH-CECSQGYTLNADKKTCSALDRCALNTH--GCEHIC 321
+D C GT C I K + C C GY + K C +D C + + GC H C
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTL 381
+N G+Y C C++G+ L D C D+C GCQ ICVN GS+ C+C+ G+ L
Sbjct: 92 INI-PGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVN-AMGSYECQCHSGFFL 149
Query: 382 NADKKTCSVRD----KCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSAT---- 433
+ ++ TC R C HGC HIC CDC PG+ L +++K C+ T
Sbjct: 150 SDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYG 209
Query: 434 ----EEARRLVSTEDACGCEATLA 453
+ + T CGC A
Sbjct: 210 NGGCQHSCEDTDTGPTCGCHQKYA 233
Score = 116 bits (290), Expect = 5e-26
Identities = 60/169 (35%), Positives = 82/169 (48%), Gaps = 6/169 (3%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
++ C + C C G C C G+TL D KTC ++ C +N GC+H C N
Sbjct: 242 IETCAVNNGGCDRTCKDTATGVR-CSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRN- 299
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
GS+ C C +GY L D +TC D+C+ C HIC+N GS C C+ GY L
Sbjct: 300 TVGSFECGCRKGYKLLTDERTCQDIDECSF-ERTCDHICINS-PGSFQCLCHRGYILYGT 357
Query: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSAT 433
C D+C++ + C CV+ SY C C PG L+ + K C T
Sbjct: 358 TH-CGDVDECSMSNGSCDQGCVNT-KGSYECVCPPGRRLHWNGKDCVET 404
Score = 114 bits (286), Expect = 2e-25
Identities = 59/175 (33%), Positives = 85/175 (48%), Gaps = 11/175 (6%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDR----CALNTHGCEHI 320
+D C CQ +C++ G + C+C G+ L+ ++ TC C HGC HI
Sbjct: 118 VDECQDNNGGCQQICVN-AMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHI 176
Query: 321 CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYT 380
C G C+C G+ L +++K C+ C G GCQH C + TG C C++ Y
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHSCEDTDTGPT-CGCHQKYA 233
Query: 381 LNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
L++D +TC + CA+ + GC C D A C C G+TL D KTC E
Sbjct: 234 LHSDGRTCI--ETCAVNNGGCDRTC-KDTATGVRCSCPVGFTLQPDGKTCKDINE 285
Score = 114 bits (284), Expect = 3e-25
Identities = 56/168 (33%), Positives = 84/168 (50%), Gaps = 7/168 (4%)
Query: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
C+ H C H+C +G C+C G+ L ++K C+ C GC+H C + +G
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHSCEDTDTG 223
Query: 328 SYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKT 387
C C++ Y L+ D +TC + CA+ GC C + TG C C G+TL D KT
Sbjct: 224 PT-CGCHQKYALHSDGRTCI--ETCAVNNGGCDRTCKDTATGVR-CSCPVGFTLQPDGKT 279
Query: 388 CSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
C ++C + + GC H C + S+ C C GY L D++TC +E
Sbjct: 280 CKDINECLVNNGGCDHFC-RNTVGSFECGCRKGYKLLTDERTCQDIDE 326
Score = 88.2 bits (217), Expect = 2e-17
Identities = 52/162 (32%), Positives = 74/162 (45%), Gaps = 8/162 (4%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
++ C++ C H C + G C C +GY L D++TC +D C+ C+HIC+N
Sbjct: 283 INECLVNNGGCDHFC-RNTVGSFECGCRKGYKLLTDERTCQDIDECSFE-RTCDHICINS 340
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
GS+ C C+ GY L C D+C++ C CVN + GS+ C C G L+ +
Sbjct: 341 -PGSFQCLCHRGYILYGTTH-CGDVDECSMSNGSCDQGCVNTK-GSYECVCPPGRRLHWN 397
Query: 385 KKTCSVRDKC---ALGSHGCQHICVSDGAASYHCDCYPGYTL 423
K C KC A S Q C G P +TL
Sbjct: 398 GKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTL 439
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 116 bits (291), Expect = 4e-26
Identities = 65/173 (37%), Positives = 88/173 (50%), Gaps = 11/173 (6%)
Query: 265 LDPCVLGTHQCQ--HVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
+D C +HQC +CI+ EG + C C+ GY L + C +D C C+ +C
Sbjct: 128 VDECATDSHQCNPTQICINT-EGGYTCSCTDGYWLLEGQ--CLDIDECRYGY--CQQLCA 182
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
N GSY C C G+TLNED ++C ++CA + C CVN GS C C GY L
Sbjct: 183 NV-PGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQTCVNTY-GSFICRCDPGYELE 239
Query: 383 ADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
D CS D+C+ CQH CV+ +Y C C PGY L +D ++C E
Sbjct: 240 EDGVHCSDMDECSFSEFLCQHECVNQ-PGTYFCSCPPGYILLDDNRSCQDINE 291
Score = 99.0 bits (245), Expect = 9e-21
Identities = 51/137 (37%), Positives = 74/137 (54%), Gaps = 6/137 (4%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C G CQ +C ++ G + C C+ G+TLN D ++C ++ CA + C CVN
Sbjct: 169 IDECRYG--YCQQLC-ANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCVQTCVNT 224
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
GS+ C C GY L ED CS D+C+ CQH CVN + G++ C C GY L D
Sbjct: 225 Y-GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVN-QPGTYFCSCPPGYILLDD 282
Query: 385 KKTCSVRDKCALGSHGC 401
++C ++C +H C
Sbjct: 283 NRSCQDINECEHRNHTC 299
Score = 73.6 bits (179), Expect = 4e-13
Identities = 56/209 (26%), Positives = 83/209 (39%), Gaps = 59/209 (28%)
Query: 285 GKHHCECSQGYTLNADKKTCSALDRCALNTHGC--EHICVNDRSGSYHC----------- 331
G +C+ G+ L+ C +D C C + +CVN ++G Y C
Sbjct: 21 GNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVN-QNGGYLCIPRTNPVYRGP 79
Query: 332 --------------------------------ECYEGYTLNEDRKTCSAQDKCALGTHGC 359
C GY ++E + C D+CA +H C
Sbjct: 80 YSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQ-CVDVDECATDSHQC 138
Query: 360 Q--HICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDC 417
IC+N G + C C +GY L + C D+C G CQ +C ++ SY C C
Sbjct: 139 NPTQICINTE-GGYTCSCTDGYWLLEGQ--CLDIDECRYGY--CQQLC-ANVPGSYSCTC 192
Query: 418 YPGYTLNEDKKTCSATEEARRLVSTEDAC 446
PG+TLNED ++C E +TE+ C
Sbjct: 193 NPGFTLNEDGRSCQDVNEC----ATENPC 217
>gi|166362728 epidermal growth factor (beta-urogastrone) [Homo
sapiens]
Length = 1207
Score = 115 bits (289), Expect = 7e-26
Identities = 62/166 (37%), Positives = 77/166 (46%), Gaps = 4/166 (2%)
Query: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
C L C H C C++GY L+ D+K C ++ CA HGC C N G
Sbjct: 318 CKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKN-TPG 376
Query: 328 SYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKT 387
SY+C C G+ L D K C C C H CV G C C EG L D KT
Sbjct: 377 SYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGP-LCFCPEGSVLERDGKT 435
Query: 388 CSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSAT 433
CS G GC +CV S+ CDC+PGY L D+K+C+A+
Sbjct: 436 CSGCSSPDNG--GCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAAS 479
Score = 61.6 bits (148), Expect = 2e-09
Identities = 51/168 (30%), Positives = 70/168 (41%), Gaps = 31/168 (18%)
Query: 279 CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHI---CVNDRSGSYHCECYE 335
CIS+GE C+C +G+ D K CS +D C + C C+N G Y C C E
Sbjct: 846 CISEGEDAT-CQCLKGFA--GDGKLCSDIDECEMGVPVCPPASSKCINTEGG-YVCRCSE 901
Query: 336 GYTLNEDRKTCSAQDKCALGTHGC-QHICVNDRTGSHHCECYEGYT-------------- 380
GY D C D+C LG H C ++ + G + C C +
Sbjct: 902 GY--QGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPH 959
Query: 381 LNADKKTCSVRD---KCALGSHG-CQH--ICV-SDGAASYHCDCYPGY 421
L D SVR+ +C L G C H +C+ + Y C+C GY
Sbjct: 960 LREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGY 1007
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 349 QDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSD 408
Q C L C SH C C EGY L+ D+K C ++CA +HGC C +
Sbjct: 315 QKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGC-KN 373
Query: 409 GAASYHCDCYPGYTLNEDKKTCSATEEARRLVS 441
SY+C C G+ L D K C R VS
Sbjct: 374 TPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVS 406
Score = 60.5 bits (145), Expect = 3e-09
Identities = 52/204 (25%), Positives = 72/204 (35%), Gaps = 58/204 (28%)
Query: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHG--------- 316
DPC+ C+H+C G C C +G+ +D KTC ALD L G
Sbjct: 743 DPCLYQNGGCEHIC-KKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVT 801
Query: 317 ----------------------CEHICVNDRSG-----------------SYHCECYEGY 337
I V+D+ C+C +G+
Sbjct: 802 PLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGF 861
Query: 338 TLNEDRKTCSAQDKCALGTHGC---QHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKC 394
D K CS D+C +G C C+N G + C C EGY D C D+C
Sbjct: 862 A--GDGKLCSDIDECEMGVPVCPPASSKCINTE-GGYVCRCSEGY--QGDGIHCLDIDEC 916
Query: 395 ALGSHGC-QHICVSDGAASYHCDC 417
LG H C ++ ++ Y C C
Sbjct: 917 QLGEHSCGENASCTNTEGGYTCMC 940
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/166 (25%), Positives = 62/166 (37%), Gaps = 22/166 (13%)
Query: 308 DRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHG-------CQ 360
D C GCEHIC R G+ C C EG+ D KTC A D L G
Sbjct: 743 DPCLYQNGGCEHIC-KKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVT 801
Query: 361 HICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 420
+ + +T E + + S +D CA C+S+G + C C G
Sbjct: 802 PLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDA-TCQCLKG 860
Query: 421 YTLNEDKKTCSATEE-----------ARRLVSTEDACGCEATLAFQ 455
+ D K CS +E + + ++TE C + +Q
Sbjct: 861 FA--GDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQ 904
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 108 bits (270), Expect = 1e-23
Identities = 58/188 (30%), Positives = 105/188 (55%), Gaps = 6/188 (3%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
CK D++F++DSS S+ P F+K+KTF+ ++ IGP ++ VV ++ K EFQ
Sbjct: 616 CKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQ 675
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L + + + A+ ++ + T++G A+ + + + F+ GAR NI K I++TD
Sbjct: 676 LNRFMSQSDISNAIDQMAHIGQTTLTGSAL-SFVSQYFSPTKGAR---PNIRKFLILITD 731
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
G QD V E A + G+ +Y+VGV +++ L+ ++ P E VFYVE + +++++
Sbjct: 732 GEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRP--EMVFYVENFDILQRIED 789
Query: 257 RFQETFCA 264
C+
Sbjct: 790 DLVFGICS 797
Score = 101 bits (251), Expect = 2e-21
Identities = 52/203 (25%), Positives = 105/203 (51%), Gaps = 5/203 (2%)
Query: 66 SEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVV 125
SE +G + D+ +ID S S + +F ++KTF+S ++ +I P RV V
Sbjct: 419 SERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAV 478
Query: 126 NYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSS 185
YA + +EF++ Y++KQ L +A+ I + T +G A+ + ++ ++ +
Sbjct: 479 QYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLS---LLQKAKKQRGN 535
Query: 186 NIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYV 245
+P +++T+G +D + E A R + I +YA+G+ A+ L+ +A E E+ V+YV
Sbjct: 536 KVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGE--EKRVYYV 593
Query: 246 ETYGVIEKLSSRFQETFCALDPC 268
+ ++ + ++ + C + C
Sbjct: 594 HDFDALKDIRNQVVQEICTEEAC 616
Score = 84.3 bits (207), Expect = 2e-16
Identities = 46/187 (24%), Positives = 97/187 (51%), Gaps = 4/187 (2%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C+ +DLVF++D S S++P +F K+K F++ ++ D+ R+ ++ T EF
Sbjct: 994 CEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFP 1053
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L + ++ + + I + T G A++ ++ F + G+R ++ P+V +++TD
Sbjct: 1054 LGTFIGEKEISFQIENIKQIFGNTHIGAALR-EVEHYFRPDMGSR-INTGTPQVLLVLTD 1111
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
G+ QD+V + A + GI++Y+VG+ D+ +++ E V + ++K++
Sbjct: 1112 GQSQDEVAQAAEALRHRGIDIYSVGI--GDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169
Query: 257 RFQETFC 263
R C
Sbjct: 1170 RIVRNIC 1176
Score = 82.0 bits (201), Expect = 1e-15
Identities = 44/166 (26%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
D+VF++D S + F +K F+ + LDI RV +V Y++ K+ L +
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
Query: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
K + Q + ++P + +G AI+ E F+ G+R+ + +P++A++VT +D
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRK-NQGVPQIAVLVTHRDSEDN 347
Query: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETY 248
V + A + G+ ++ +G++ A L+ +AS P E++V ++T+
Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTF 393
Score = 79.0 bits (193), Expect = 9e-15
Identities = 56/198 (28%), Positives = 95/198 (47%), Gaps = 13/198 (6%)
Query: 75 GVCKSRP-------LDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNY 127
G+C R LD+VF+IDSS S+ E+ +K F+ ++ D+G R + Y
Sbjct: 794 GICSPREECKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKY 853
Query: 128 ASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNI 187
A ++ F L + K + + + T + A+ + D FT G+R + +
Sbjct: 854 ADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEARGSR-LNKGV 911
Query: 188 PKVAIIVTDGRPQ--DQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYV 245
P+V I++TDG D++N A + GI + AVG+D A+ L MA + F+V
Sbjct: 912 PQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGS--SDKYFFV 969
Query: 246 ETYGVIEKLSSRFQETFC 263
ET+G ++ + S + C
Sbjct: 970 ETFGGLKGIFSDVTASVC 987
Score = 70.1 bits (170), Expect = 4e-12
Identities = 41/154 (26%), Positives = 77/154 (50%), Gaps = 2/154 (1%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
D+VF++DSS + F VK F++++I +L I RVA+ Y+ + EF L +
Sbjct: 27 DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
Query: 143 KQSLKQAVGRITPLSTGTMS-GLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQD 201
+ + + + G++ G A+Q A F+ A R+ P + +++ +D
Sbjct: 87 RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRD-KKQFPPILVVLASSESED 145
Query: 202 QVNEVAARAQASGIELYAVGVDRADMASLKMMAS 235
V E + + G+++ +VGV +A +LK MA+
Sbjct: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMAT 179
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 108 bits (270), Expect = 1e-23
Identities = 65/228 (28%), Positives = 88/228 (38%), Gaps = 43/228 (18%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C + H C H + G C C GYT +A TC +D C+ C +C N
Sbjct: 2364 VDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNT 2423
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN------------------- 365
+ GS+ C C GY L ED +TC D+C H CQ +CVN
Sbjct: 2424 K-GSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQA 2482
Query: 366 ---------------------DRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
+ GS CEC++G+TL + C ++C G H CQH
Sbjct: 2483 CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRCQHG 2541
Query: 405 CVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACGCEATL 452
C + Y C C G+T + C E T + C TL
Sbjct: 2542 C-QNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTL 2588
Score = 107 bits (266), Expect = 3e-23
Identities = 58/183 (31%), Positives = 82/183 (44%), Gaps = 7/183 (3%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
++ C + C CI+ EG + C C QGY+L D + C+ +D C N C+ +
Sbjct: 1156 INECRVQNGGCDVHCINT-EGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTN 1214
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
G + C CY+G+ D +TC D+C L H C H + GS C C GY +
Sbjct: 1215 MPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKG 1274
Query: 385 KKTCSVRDKCALGSHGC-QHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTE 443
CS D+C +G H C H + S+ C C PG+ D C +E VS E
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHDLDEC---VSQE 1329
Query: 444 DAC 446
C
Sbjct: 1330 HRC 1332
Score = 102 bits (255), Expect = 6e-22
Identities = 52/174 (29%), Positives = 84/174 (48%), Gaps = 8/174 (4%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-IC 321
CA DP + C+ ++ +G + C+C G+ L A C +D C+L+ C H C
Sbjct: 1075 CARDPLL-----CRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQC 1129
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTL 381
VN G++ C C+ G+ DR+ C ++C + GC C+N GS+ C C +GY+L
Sbjct: 1130 VNV-IGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GSYRCSCGQGYSL 1187
Query: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
D + C+ D+C C ++ + C CY G+ D +TC +E
Sbjct: 1188 MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDE 1241
Score = 95.5 bits (236), Expect = 1e-19
Identities = 50/175 (28%), Positives = 81/175 (46%), Gaps = 3/175 (1%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC-EHICVN 323
++ C + C H + G HC C+ G+ L+A ++ C+ +D C ++ C + CVN
Sbjct: 987 VNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVN 1046
Query: 324 DRSGSYHCECYEGYTLN-EDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
GS+ CEC+ GY K C D+CA C+ + GS+ C+C G+ L
Sbjct: 1047 T-PGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 383 ADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEAR 437
A C D+C+L C H + ++ C C+ G+ D++ C E R
Sbjct: 1106 AKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECR 1160
Score = 94.4 bits (233), Expect = 2e-19
Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 43/211 (20%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVN- 323
+D C C +C + +G C C +GY L D +TC LD C H C+ +CVN
Sbjct: 2406 MDECSQVPKPCTFLC-KNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNT 2464
Query: 324 ---------------------------------------DRSGSYHCECYEGYTLNEDRK 344
+ GS+ CEC++G+TL
Sbjct: 2465 VGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGH 2524
Query: 345 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
C ++C G H CQH C N + G + C C +G+T ++ C ++CAL C
Sbjct: 2525 GCEDVNECD-GPHRCQHGCQN-QLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 405 CVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
+ + C C G+ ++ C +E
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGCQEVDE 2613
Score = 92.4 bits (228), Expect = 8e-19
Identities = 56/181 (30%), Positives = 82/181 (45%), Gaps = 7/181 (3%)
Query: 259 QETFCA-LDPCVLGTHQC-QHVCISDGEGKHHCECSQGYTLNAD-KKTCSALDRCALNTH 315
QE C +D C + C Q C++ G CEC GY K C +D CA +
Sbjct: 1022 QERNCTDIDECRISPDLCGQGTCVNT-PGSFECECFPGYESGFMLMKNCMDVDECARDPL 1080
Query: 316 GCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH-ICVNDRTGSHHCE 374
C + GSY C+C G+ L C D+C+L C H CVN G+ C
Sbjct: 1081 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVN-VIGAFQCS 1139
Query: 375 CYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATE 434
C+ G+ D++ C ++C + + GC C++ SY C C GY+L D + C+ +
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGCDVHCINT-EGSYRCSCGQGYSLMPDGRACADVD 1198
Query: 435 E 435
E
Sbjct: 1199 E 1199
Score = 85.1 bits (209), Expect = 1e-16
Identities = 54/176 (30%), Positives = 83/176 (47%), Gaps = 10/176 (5%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVN 323
+D C T+ C + + CEC+ GYT + + C +D C + C H CVN
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDV-RGECIDVDEC--TSSPCHHGDCVN 465
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHI--CVNDRTGSHHCECYEGYTL 381
G+YHC CY G+ R+ C D+C + + G H+ CVN GS C C G+ L
Sbjct: 466 -IPGTYHCRCYPGFQATPTRQACVDVDECIV-SGGLCHLGRCVNTE-GSFQCVCNAGFEL 522
Query: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEAR 437
+ D K C ++CA + +C+++ S+ C C PG+ L C +E +
Sbjct: 523 SPDGKNCVDHNECATSTMCVNGVCLNED-GSFSCLCKPGFLLAPGGHYCMDIDECQ 577
Score = 82.4 bits (202), Expect = 8e-16
Identities = 54/182 (29%), Positives = 76/182 (41%), Gaps = 7/182 (3%)
Query: 265 LDPCVLGTHQC--QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
LD CV H+C + C++ G + C C QG+ D C D CA N C++
Sbjct: 1322 LDECVSQEHRCSPRGDCLNV-PGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQC 1378
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
+ G Y CEC G+ ED + C D+CA G C N G C C GY L+
Sbjct: 1379 LNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN-LPGMFRCICNGGYELD 1437
Query: 383 ADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVST 442
C+ ++CA + +C++ SY C C + LN C T + T
Sbjct: 1438 RGGGNCTDINECADPVNCINGVCINT-PGSYLCSCPQDFELNPSGVGCVDTRAGNCFLET 1496
Query: 443 ED 444
D
Sbjct: 1497 HD 1498
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/168 (29%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Query: 278 VCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--ICVNDRSGSYHCECYE 335
+CI+ G CEC G+ N+ C +D C C+ C+N GSY C+C
Sbjct: 1736 ICINQ-IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN-IPGSYRCKCTR 1793
Query: 336 GYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKC- 394
GY L+ C +++C + C H D GS+ C C+ G+ +AD+ C D+C
Sbjct: 1794 GYKLSPG-GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECD 1852
Query: 395 --ALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLV 440
G+ C++I SY+C C+PG+ + + C +E LV
Sbjct: 1853 RQPCGNGTCKNI-----IGSYNCLCFPGFVVTHN-GDCVDFDECTTLV 1894
Score = 81.3 bits (199), Expect = 2e-15
Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 7/164 (4%)
Query: 258 FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC 317
F C+ P G H H + G CEC QG+TL + C ++ C H C
Sbjct: 2484 FDNDECSAQPGPCGAHGHCH----NTPGSFRCECHQGFTLVSSGHGCEDVNECD-GPHRC 2538
Query: 318 EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYE 377
+H C N + G Y C C +G+T + C +++CAL C + G C C
Sbjct: 2539 QHGCQN-QLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPS 2597
Query: 378 GYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY 421
G+ + C D+CA C + C ++ + C C GY
Sbjct: 2598 GFDFDQALGGCQEVDECAGRRGPCSYSC-ANTPGGFLCGCPQGY 2640
Score = 79.3 bits (194), Expect = 7e-15
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 18/186 (9%)
Query: 265 LDPCVLGTHQCQHV--CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
+D C CQ CI+ G + C+C++GY L+ C + C + C H
Sbjct: 1764 VDECGSRESPCQQNADCINI-PGSYRCKCTRGYKLSPGG-ACVGRNECREIPNVCSHGDC 1821
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKC---ALGTHGCQHICVNDRTGSHHCECYEGY 379
D GSY C C+ G+ + D+ C D+C G C++I GS++C C+ G+
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNII-----GSYNCLCFPGF 1876
Query: 380 --TLNADKKTCSVRDKC-ALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEA 436
T N D C D+C L C+ + A S+HC C G+ L D K C T E
Sbjct: 1877 VVTHNGD---CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNEC 1933
Query: 437 RRLVST 442
L T
Sbjct: 1934 LSLAGT 1939
Score = 79.0 bits (193), Expect = 9e-15
Identities = 50/175 (28%), Positives = 76/175 (43%), Gaps = 16/175 (9%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHI--CV 322
+D C + C H + G +HC C G+ ++ C +D C ++ C H+ CV
Sbjct: 450 VDECT--SSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLC-HLGRCV 506
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
N GS+ C C G+ L+ D K C ++CA T +C+N+ GS C C G+ L
Sbjct: 507 N-TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNE-DGSFSCLCKPGFLLA 564
Query: 383 ADKKTCSVRDKCALGSHGCQHICV----SDGAASYHCDCYPGYTLNEDKKTCSAT 433
C D+C ICV ++ S+ C C G + D + C T
Sbjct: 565 PGGHYCMDIDECQTPG-----ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Score = 78.2 bits (191), Expect = 2e-14
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 2/152 (1%)
Query: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECY 334
C H D EG + C C +G+ +AD+ C +D C + C + + GSY+C C+
Sbjct: 1816 CSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDEC--DRQPCGNGTCKNIIGSYNCLCF 1873
Query: 335 EGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKC 394
G+ + + + L C+ + GS HC C +G+ L AD K C ++C
Sbjct: 1874 PGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNEC 1933
Query: 395 ALGSHGCQHICVSDGAASYHCDCYPGYTLNED 426
+ C + S+ C C PG+ + D
Sbjct: 1934 LSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD 1965
Score = 76.6 bits (187), Expect = 5e-14
Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 21/163 (12%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
CALDP V C+++ G + C C+ GY A K C+ +D CALN+ C++
Sbjct: 686 CALDPEVCANGVCENL-----RGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWC 740
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEG---- 378
+ GSY C C G+ +D + C D+C L + +C N GS+ C+C G
Sbjct: 741 QNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRN-LAGSYTCKCGPGSRLD 798
Query: 379 ----YTLNADKKTCSVR---DKCALGSHGC---QHICVSDGAA 411
+ L++ K TC ++ +C + G C + GAA
Sbjct: 799 PSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAA 841
Score = 74.7 bits (182), Expect = 2e-13
Identities = 57/191 (29%), Positives = 81/191 (42%), Gaps = 15/191 (7%)
Query: 248 YGVIEKLSSR-------FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNAD 300
YG IEK S + C +P CQ +C + + CS G + D
Sbjct: 621 YGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQ-LCPAKDSAEFQALCSSGLGITTD 679
Query: 301 KKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGC 359
+ ++ CAL+ C + +C N R GSY C C GY K C+ D+CAL + C
Sbjct: 680 GRD---INECALDPEVCANGVCENLR-GSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735
Query: 360 QHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYP 419
+ + GS+ C C G+ D + C D+C L S +C + A SY C C P
Sbjct: 736 DNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVC-RNLAGSYTCKCGP 793
Query: 420 GYTLNEDKKTC 430
G L+ C
Sbjct: 794 GSRLDPSGTFC 804
Score = 73.2 bits (178), Expect = 5e-13
Identities = 51/163 (31%), Positives = 72/163 (44%), Gaps = 14/163 (8%)
Query: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 325
D C +G H C ++ G C C+ G+ TC +D C+LN C C N
Sbjct: 2128 DECSVG-HPCGQGTCTNVIGGFECACADGFEPGL-MMTCEDIDECSLNPLLCAFRCHNTE 2185
Query: 326 SGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGC--QHICVNDRTGSHHCECYEGY-TLN 382
GSY C C GYTL ED C D+CA G C + + + G+ C C G L
Sbjct: 2186 -GSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLP 2244
Query: 383 ADKKTCSVRDKCALGSHGCQHICVS----DGAASYHCDCYPGY 421
+ C+ ++C H +CV+ + A S+ CDC G+
Sbjct: 2245 GSGEGCTDDNEC----HAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Score = 72.8 bits (177), Expect = 7e-13
Identities = 59/212 (27%), Positives = 84/212 (39%), Gaps = 20/212 (9%)
Query: 256 SRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTH 315
SR CA +P V C + +G CEC GY+L+ C D C++ H
Sbjct: 2081 SREDVNECAENPGVCTNGVCVNT-----DGSFRCECPFGYSLDFTGINCVDTDECSVG-H 2134
Query: 316 GCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCEC 375
C + G + C C +G+ TC D+C+L C C N GS+ C C
Sbjct: 2135 PCGQGTCTNVIGGFECACADGFEPGL-MMTCEDIDECSLNPLLCAFRCHNTE-GSYLCTC 2192
Query: 376 YEGYTLNADKKTCSVRDKCALGSHGC--QHICVSDGAASYHCDCYPGY-TLNEDKKTCSA 432
GYTL D C D+CA G C + + + ++ C C PG L + C+
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTD 2252
Query: 433 TEEAR---------RLVSTEDACGCEATLAFQ 455
E R V+T + C+ FQ
Sbjct: 2253 DNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Score = 72.0 bits (175), Expect = 1e-12
Identities = 52/172 (30%), Positives = 73/172 (42%), Gaps = 14/172 (8%)
Query: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGY-TLNADKKTCSALDRCALNTHGCEH-ICVN 323
DPC L C +G C G+ + + ++ CA N C + +CVN
Sbjct: 2051 DPCEL--------CPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVN 2102
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNA 383
GS+ CEC GY+L+ C D+C++G H C + G C C +G+
Sbjct: 2103 T-DGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 384 DKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
TC D+C+L C C + SY C C GYTL ED C +E
Sbjct: 2161 -MMTCEDIDECSLNPLLCAFRC-HNTEGSYLCTCPAGYTLREDGAMCRDVDE 2210
Score = 67.4 bits (163), Expect = 3e-11
Identities = 50/193 (25%), Positives = 77/193 (39%), Gaps = 37/193 (19%)
Query: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTC----------SALDR--------------- 309
C + ++ EG C+C G + D + C A+++
Sbjct: 582 CVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSE 641
Query: 310 --CALNTHG----CEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH-I 362
CA HG C+ +C S + C G + D + + +CAL C + +
Sbjct: 642 CCCANPDHGFGEPCQ-LCPAKDSAEFQALCSSGLGITTDGRDIN---ECALDPEVCANGV 697
Query: 363 CVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYT 422
C N R GS+ C C GY A K C+ D+CAL S C + + SY C C PG+
Sbjct: 698 CENLR-GSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFH 756
Query: 423 LNEDKKTCSATEE 435
+D + C +E
Sbjct: 757 FWQDTEICKDVDE 769
Score = 67.4 bits (163), Expect = 3e-11
Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 6/143 (4%)
Query: 307 LDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHI--C 363
+D C C + IC+N + GS+ CEC G+ N C D+C CQ C
Sbjct: 1722 IDECGEIPAICANGICIN-QIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADC 1780
Query: 364 VNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTL 423
+N GS+ C+C GY L+ C R++C + C H D SY C C+ G+
Sbjct: 1781 INI-PGSYRCKCTRGYKLSPGG-ACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 424 NEDKKTCSATEEARRLVSTEDAC 446
+ D+ C +E R C
Sbjct: 1839 SADQTLCMDIDECDRQPCGNGTC 1861
Score = 54.7 bits (130), Expect = 2e-07
Identities = 53/251 (21%), Positives = 82/251 (32%), Gaps = 81/251 (32%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCE------ 318
+D C L C C + EG + C C GYTL D C +D CA C
Sbjct: 2167 IDECSLNPLLCAFRC-HNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMEC 2225
Query: 319 -----------------------------------HICVNDR----SGSYHCECYEGY-- 337
+CVN R +GS+ C+C EG+
Sbjct: 2226 KNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQP 2285
Query: 338 -------------------------TLNEDRKTCSAQDKCALGTHG----CQHICVNDRT 368
+L+ + + + C G G C+ +C T
Sbjct: 2286 SPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCE-LCPLPGT 2344
Query: 369 GSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKK 428
++ C G A+ + D+C + +H C H + S+ C C GYT +
Sbjct: 2345 SAYRKLCPHGSGYTAEGRDV---DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATAT 2401
Query: 429 TCSATEEARRL 439
TC +E ++
Sbjct: 2402 TCLDMDECSQV 2412
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/113 (29%), Positives = 49/113 (43%), Gaps = 19/113 (16%)
Query: 359 CQH---ICVNDRT----GSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAA 411
C+H +C+N R S+ CEC GYT + + C D+C S C H +
Sbjct: 412 CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDV-RGECIDVDECT--SSPCHHGDCVNIPG 468
Query: 412 SYHCDCYPGYTLNEDKKTCSATEEA---------RRLVSTEDACGCEATLAFQ 455
+YHC CYPG+ ++ C +E R V+TE + C F+
Sbjct: 469 TYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFE 521
Score = 43.5 bits (101), Expect = 4e-04
Identities = 51/233 (21%), Positives = 78/233 (33%), Gaps = 80/233 (34%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C L + C + + G + C C G+ D + C +D C L++ +C N
Sbjct: 725 VDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC-LSSPCVSGVCRN- 782
Query: 325 RSGSYHCECYEG--------YTLNEDRKTC---SAQDKCALGTHG--------------- 358
+GSY C+C G + L+ + TC + +C + G
Sbjct: 783 LAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAW 842
Query: 359 ---CQH------------------------------ICVNDR----TGSHHCECYEGYTL 381
C+ +C N R GS CEC EG L
Sbjct: 843 GSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLML 902
Query: 382 NADKKTC-SVR----------DKCAL---GSHGCQHICVSDGAA-SYHCDCYP 419
+A + C VR D+C + G + C S GA C+ P
Sbjct: 903 DASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP 955
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/231 (22%), Positives = 87/231 (37%), Gaps = 45/231 (19%)
Query: 257 RFQETFCA--LDPCVLGTHQCQHVCISDGEGKHHCE----CSQGYTLNADKKTCSALDRC 310
+ QE+ C L L + C + + G CE C++G+ TC ++ C
Sbjct: 815 KIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFA-RMTGVTCDDVNEC 873
Query: 311 ALNTHGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTCS-----------AQDKCALGTHG 358
C + CVN +GS+ CEC EG L+ + C +D+C + G
Sbjct: 874 ESFPGVCPNGRCVNT-AGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPG 932
Query: 359 CQHI----CVNDRTGSHHCE-CYEGYTLN-----------ADKKTCSVR------DKCAL 396
+ C CE C + +L A + S R ++C +
Sbjct: 933 KYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKV 992
Query: 397 GSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACG 447
C H + S+HC C G+ L+ ++ C+ +E R + D CG
Sbjct: 993 FPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECR---ISPDLCG 1040
Score = 40.8 bits (94), Expect = 0.003
Identities = 54/215 (25%), Positives = 72/215 (33%), Gaps = 44/215 (20%)
Query: 278 VCISDGEGKHHCECSQGYTLNADKKTC--SALDRCALNTHG------------------- 316
VCI+ G + C C Q + LN C + C L TH
Sbjct: 1459 VCINT-PGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA 1517
Query: 317 -------------CEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQD--KCALGTHGCQH 361
CE +C + Y C G +R T +D +C CQ
Sbjct: 1518 SCCCSLGRAWGNPCE-LCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQG 1576
Query: 362 -ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPG 420
CVN GS CEC GY L+ + C D+C+ S C + +Y C C
Sbjct: 1577 GDCVNT-FGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAE 1635
Query: 421 YTLNEDKKTCSATEEARRLVSTEDACG-CEATLAF 454
Y C + R+ V G C+ LAF
Sbjct: 1636 YLQVNGGNNCM---DMRKSVCFRHYNGTCQNELAF 1667
Score = 40.4 bits (93), Expect = 0.004
Identities = 43/204 (21%), Positives = 64/204 (31%), Gaps = 34/204 (16%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C CQ + G CEC GY L+ + C +D C+ ++ C +
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYN 1623
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTH---GCQHICVNDRTGSHHCECYE-GYT 380
G+Y C C Y C K H CQ+ + T C Y G
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 381 LNADKKTCSVR----------------------------DKCALGSHGCQH-ICVSDGAA 411
N + C D+C C + IC++
Sbjct: 1684 WNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQ-IG 1742
Query: 412 SYHCDCYPGYTLNEDKKTCSATEE 435
S+ C+C G+ N C +E
Sbjct: 1743 SFRCECPAGFNYNSILLACEDVDE 1766
Score = 38.1 bits (87), Expect = 0.018
Identities = 44/182 (24%), Positives = 60/182 (32%), Gaps = 40/182 (21%)
Query: 275 CQHVCISDGEGKH-HCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCEC 333
C C++ G + C C +GYT T C H C+ G C C
Sbjct: 120 CSVSCMNGGTCRGASCLCQKGYT-----GTVCGQPICDRGCHNGGR-CI----GPNRCAC 169
Query: 334 YEGYT---LNEDRKT--CSAQDKCALGTHGCQH-----ICVN-------DRTGSHHCE-- 374
G+ D +T C Q +G GCQH +C R CE
Sbjct: 170 VYGFMGPQCERDYRTGPCFGQ----VGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELC 225
Query: 375 ------CYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKK 428
C G+ N C D+C CQ + S+HC C G+ L++
Sbjct: 226 PAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSA 285
Query: 429 TC 430
C
Sbjct: 286 AC 287
Score = 37.0 bits (84), Expect = 0.040
Identities = 37/146 (25%), Positives = 50/146 (34%), Gaps = 29/146 (19%)
Query: 269 VLGTHQCQHVCISDGE--GKHHCECSQGYT---LNADKKTCSALDRCALNTHGCEH---- 319
V G C C + G G + C C G+ D +T + + GC+H
Sbjct: 145 VCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQ--VGPEGCQHQLTG 202
Query: 320 -ICVN-------DRSGSYHCE--------CYEGYTLNEDRKTCSAQDKCALGTHGCQH-I 362
+C R+ CE C G+ N C D+C CQ
Sbjct: 203 LVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGS 262
Query: 363 CVNDRTGSHHCECYEGYTLNADKKTC 388
CVN GS HC C G+ L+ C
Sbjct: 263 CVN-MVGSFHCRCPVGHRLSDSSAAC 287
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 108 bits (269), Expect = 1e-23
Identities = 51/162 (31%), Positives = 84/162 (51%), Gaps = 3/162 (1%)
Query: 262 FCA-LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHI 320
FC +D C + C+ C ++ EG + C C G+ L D+++C+ +D C N + C+
Sbjct: 1194 FCVDIDECSIMNGGCETFC-TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGG 1252
Query: 321 CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYT 380
+ G Y C CY+G+ +ED KTC ++C L + C + GS C C GY+
Sbjct: 1253 QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYS 1312
Query: 381 LNADKKTCSVRDKCALGSHGC-QHICVSDGAASYHCDCYPGY 421
K C+ ++C +G+H C +H ++ A S+ C C PG+
Sbjct: 1313 GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
Score = 107 bits (267), Expect = 2e-23
Identities = 55/172 (31%), Positives = 82/172 (47%), Gaps = 3/172 (1%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVN 323
+D C C+ + EG + CEC G+ L+ + C ++ C L+ H C + CVN
Sbjct: 1114 IDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVN 1173
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNA 383
G Y C C GY DR C D+C++ GC+ C N GS+ C C G+ L
Sbjct: 1174 -LIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSE-GSYECSCQPGFALMP 1231
Query: 384 DKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
D+++C+ D+C + C ++ Y C CY G+ +ED KTC E
Sbjct: 1232 DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNE 1283
Score = 104 bits (260), Expect = 2e-22
Identities = 51/171 (29%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
++ C L H C + + GK+ C C+ GY D+ C +D C++ GCE C N
Sbjct: 1156 INECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNS 1215
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
GSY C C G+ L D+++C+ D+C + C + G + C CY+G+ + D
Sbjct: 1216 E-GSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASED 1274
Query: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
KTC ++C L + C + S+ C C GY+ + K C+ E
Sbjct: 1275 MKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINE 1325
Score = 102 bits (253), Expect = 1e-21
Identities = 56/174 (32%), Positives = 88/174 (50%), Gaps = 9/174 (5%)
Query: 265 LDPCVLGTHQCQH-VCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVN 323
+D C + C++ C++D G +HC C GYT + +C L+ C C IC N
Sbjct: 2403 IDECKVIHDVCRNGECVND-RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKN 2461
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNA 383
GSY C C +GY L ED ++C D+CA H CQ +CVN G C+C G+T +
Sbjct: 2462 TE-GSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVN-TIGGFTCKCPPGFTQH- 2518
Query: 384 DKKTCSVRDKCA--LGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
+C ++C + G + IC + S+ C+C G++L++ +C +E
Sbjct: 2519 -HTSCIDNNECTSDINLCGSKGIC-QNTPGSFTCECQRGFSLDQTGSSCEDVDE 2570
Score = 99.4 bits (246), Expect = 7e-21
Identities = 53/175 (30%), Positives = 83/175 (47%), Gaps = 9/175 (5%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLN-ADKKTCSALDRCALNTHGCEHIC 321
C + P + G QC + G C+C +GY K C +D C + C
Sbjct: 1074 CRISPDLCGRGQCVNT-----PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGV 1128
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH-ICVNDRTGSHHCECYEGYT 380
++ GSY CEC G+ L+ + C ++C L H C + CVN G + C C GY
Sbjct: 1129 CHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVN-LIGKYQCACNPGYH 1187
Query: 381 LNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
D+ C D+C++ + GC+ C ++ SY C C PG+ L D+++C+ +E
Sbjct: 1188 STPDRLFCVDIDECSIMNGGCETFC-TNSEGSYECSCQPGFALMPDQRSCTDIDE 1241
Score = 96.7 bits (239), Expect = 4e-20
Identities = 53/184 (28%), Positives = 86/184 (46%), Gaps = 6/184 (3%)
Query: 254 LSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
++S +T ++ C L + C + +G C C GY+ K C+ ++ C +
Sbjct: 1270 MASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
Query: 314 THGC-EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGC-QHICVNDRTGSH 371
H C +H + +GS+ C C G+ D C+ D+C+ GTH C QH + GS+
Sbjct: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSY 1387
Query: 372 HCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCS 431
C C EGYT D TC+ D+C+ + C + + Y C+C G+ + D K C
Sbjct: 1388 RCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE 1445
Query: 432 ATEE 435
+E
Sbjct: 1446 DIDE 1449
Score = 96.7 bits (239), Expect = 4e-20
Identities = 61/229 (26%), Positives = 88/229 (38%), Gaps = 49/229 (21%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVN- 323
L+ C C +C + EG + C C +GY L D ++C LD CA H C+ +CVN
Sbjct: 2445 LNECNQAPKPCNFIC-KNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNT 2503
Query: 324 ---------------------------------------DRSGSYHCECYEGYTLNEDRK 344
+ GS+ CEC G++L++
Sbjct: 2504 IGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGS 2563
Query: 345 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
+C D+C G H CQH C N G + C C +GY + C ++C L +H C
Sbjct: 2564 SCEDVDECE-GNHRCQHGCQN-IIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGA 2620
Query: 405 CVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDAC--GCEAT 451
+ SY C C G+ + C E S + C GC T
Sbjct: 2621 SCHNTLGSYKCMCPAGFQYEQFSGGCQDINECG---SAQAPCSYGCSNT 2666
Score = 94.7 bits (234), Expect = 2e-19
Identities = 59/174 (33%), Positives = 82/174 (47%), Gaps = 13/174 (7%)
Query: 265 LDPCVLGTHQC-QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVN 323
LD C GTH C QH + G + C C +GYT D TC+ LD C+ N + C +
Sbjct: 1364 LDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQCL 1421
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICV----NDRTGSHHCECYEGY 379
+ G Y CEC G+ + D K C D+C+L +ICV ++ G CEC GY
Sbjct: 1422 NAPGGYRCECDMGFVPSADGKACEDIDECSL-----PNICVFGTCHNLPGLFRCECEIGY 1476
Query: 380 TLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSAT 433
L+ C+ ++C + CV+ SY CDC P + LN + C T
Sbjct: 1477 ELDRSGGNCTDVNECLDPTTCISGNCVNT-PGSYICDCPPDFELNPTRVGCVDT 1529
Score = 94.4 bits (233), Expect = 2e-19
Identities = 53/173 (30%), Positives = 82/173 (47%), Gaps = 13/173 (7%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-IC 321
C +PC G CI++ +G + C+C GY + C +D C N C + C
Sbjct: 494 CEKNPCAGGE------CINN-QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRC 546
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTL 381
+N GS+HC C G+ + D K C D+C++ +C+N+ GS C C G+ L
Sbjct: 547 INT-DGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINE-DGSFKCICKPGFQL 604
Query: 382 NADKKTCSVRDKCALGSHGCQHICV-SDGAASYHCDCYPGYTLNEDKKTCSAT 433
+D + C ++C CV +DG SY C+C+PG + D + C T
Sbjct: 605 ASDGRYCKDINECETPGICMNGRCVNTDG--SYRCECFPGLAVGLDGRVCVDT 655
Score = 93.6 bits (231), Expect = 4e-19
Identities = 53/175 (30%), Positives = 83/175 (47%), Gaps = 11/175 (6%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
C +P + QC ++ G++ C C G+ + D KTC ++ C LN + C
Sbjct: 1242 CEDNPNICDGGQCTNI-----PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTC 1296
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGC-QHICVNDRTGSHHCECYEGYTL 381
+ GS+ C C GY+ + + C+ ++C +G H C +H + GS C C G+
Sbjct: 1297 ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI- 1355
Query: 382 NADKKTCSVRDKCALGSHGC-QHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
D C+ D+C+ G+H C QH + SY C C GYT D TC+ +E
Sbjct: 1356 -GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDE 1407
Score = 91.7 bits (226), Expect = 1e-18
Identities = 56/173 (32%), Positives = 80/173 (46%), Gaps = 13/173 (7%)
Query: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 325
+PC GT C++V G C C +G+ TC ++ CA N C CVN
Sbjct: 2174 NPCGNGT--CKNVI-----GGFECTCEEGFE-PGPMMTCEDINECAQNPLLCAFRCVNTY 2225
Query: 326 SGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGC---QHICVNDRTGSHHCECYEGYTLN 382
GSY C+C GY L EDR+ C +D+C G H C Q C N G++ C C GY
Sbjct: 2226 -GSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKN-LIGTYMCICGPGYQRR 2283
Query: 383 ADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
D + C ++C C++ + SY C+C G+T + ++ C E
Sbjct: 2284 PDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNRE 2336
Score = 90.5 bits (223), Expect = 3e-18
Identities = 59/194 (30%), Positives = 90/194 (46%), Gaps = 16/194 (8%)
Query: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN-THGCEHICVND 324
D C L + CQ+ G CEC++G+ L+ + C +D C N G E C+N+
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDL-RGECIDVDECEKNPCAGGE--CINN 507
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNA 383
+ GSY C+C GY R C D+C C + C+N GS HC C G+ +
Sbjct: 508 Q-GSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN-TDGSFHCVCNAGFHVTR 565
Query: 384 DKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEAR------ 437
D K C D+C++ + +C+++ S+ C C PG+ L D + C E
Sbjct: 566 DGKNCEDMDECSIRNMCLNGMCINED-GSFKCICKPGFQLASDGRYCKDINECETPGICM 624
Query: 438 --RLVSTEDACGCE 449
R V+T+ + CE
Sbjct: 625 NGRCVNTDGSYRCE 638
Score = 84.0 bits (206), Expect = 3e-16
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 6/155 (3%)
Query: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECY 334
C H D G +C C G+ N D+ C ++ C + C + + GS++C C
Sbjct: 1860 CSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA--CGNGTCRNTIGSFNCRCN 1917
Query: 335 EGYTLNEDRKTCSAQDKCALGTHG-CQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRD 392
G+ L+ + C D+CA G C++ C+N GS C+C EGY + D +TC +
Sbjct: 1918 HGFILSHNND-CIDVDECASGNGNLCRNGQCINT-VGSFQCQCNEGYEVAPDGRTCVDIN 1975
Query: 393 KCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDK 427
+C L C + SY C C PGY+L +K
Sbjct: 1976 ECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK 2010
Score = 77.0 bits (188), Expect = 4e-14
Identities = 51/170 (30%), Positives = 79/170 (46%), Gaps = 13/170 (7%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCAL-NTHGCEH-I 320
C D C GT C++ G +C C+ G+ L+ + C +D CA N + C +
Sbjct: 1895 CERDACGNGT--CRNTI-----GSFNCRCNHGFILSHNND-CIDVDECASGNGNLCRNGQ 1946
Query: 321 CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYT 380
C+N GS+ C+C EGY + D +TC ++C L C + GS+ C C GY+
Sbjct: 1947 CINT-VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYS 2005
Query: 381 LNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
L +K C D+C C S+ S+ C C G++L+ + C
Sbjct: 2006 LQNEK--CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC 2053
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/165 (27%), Positives = 77/165 (46%), Gaps = 12/165 (7%)
Query: 274 QCQH--VCISDGE-----GKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRS 326
+CQ+ VC + E G + C+C GY + + C+ + C + C H D
Sbjct: 1811 ECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTV 1869
Query: 327 GSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKK 386
GS++C C+ G+ N+D+ C ++C C + + GS +C C G+ L+ +
Sbjct: 1870 GSFYCLCHTGFKTNDDQTMCLDINECE--RDACGNGTCRNTIGSFNCRCNHGFILSHNND 1927
Query: 387 TCSVRDKCALGSHG-CQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
V D+CA G+ C++ + S+ C C GY + D +TC
Sbjct: 1928 CIDV-DECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC 1971
Score = 73.6 bits (179), Expect = 4e-13
Identities = 46/144 (31%), Positives = 69/144 (47%), Gaps = 12/144 (8%)
Query: 307 LDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHI--C 363
+D C CE+ +C+N GS+ CEC G+ N+ C D+C G CQ C
Sbjct: 1767 IDECREIPGVCENGVCIN-MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV-CQRNAEC 1824
Query: 364 VNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTL 423
+N GS+ C+C GY + + C+ R++C + C H D S++C C+ G+
Sbjct: 1825 INT-AGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKT 1882
Query: 424 NEDKKTCSATEEARRLVSTEDACG 447
N+D+ C E R DACG
Sbjct: 1883 NDDQTMCLDINECER-----DACG 1901
Score = 71.6 bits (174), Expect = 1e-12
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 7/126 (5%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
CALDP + C+++ G + C C+ GY +++ K C ++ C LN+ C++
Sbjct: 727 CALDPDICPNGICENL-----RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQC 781
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
+ GS+ C C +G+ D KTC D+C + C + + GS CEC TL+
Sbjct: 782 RNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVCKNSPGSFICECSSESTLD 839
Query: 383 ADKKTC 388
K C
Sbjct: 840 PTKTIC 845
Score = 70.1 bits (170), Expect = 4e-12
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 9/175 (5%)
Query: 260 ETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH 319
E CA G CQ C + ++ CS G + + S ++ CAL+ C +
Sbjct: 682 ECCCASTEYAFG-EPCQP-CPAQNSAEYQALCSSGPGMTS---AGSDINECALDPDICPN 736
Query: 320 -ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEG 378
IC N R G+Y C C GY ++ K C ++C L + C + + GS C C +G
Sbjct: 737 GICENLR-GTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKG 795
Query: 379 YTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSAT 433
+ D KTC D+C S C + + S+ C+C TL+ K C T
Sbjct: 796 FIYKPDLKTCEDIDECE--SSPCINGVCKNSPGSFICECSSESTLDPTKTICIET 848
Score = 69.7 bits (169), Expect = 6e-12
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--ICV 322
+D C C++ + G CEC G+ N C +D C N C+ C+
Sbjct: 1767 IDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECI 1825
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
N +GSY C+C GY + C+ +++C + C H D GS +C C+ G+ N
Sbjct: 1826 N-TAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 1883
Query: 383 ADKKTCSVRDKC---ALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATE 434
D+ C ++C A G+ C++ S++C C G+ L+ + E
Sbjct: 1884 DDQTMCLDINECERDACGNGTCRNT-----IGSFNCRCNHGFILSHNNDCIDVDE 1933
Score = 63.9 bits (154), Expect = 3e-10
Identities = 57/205 (27%), Positives = 81/205 (39%), Gaps = 35/205 (17%)
Query: 266 DPCVLGTHQC---QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-IC 321
D C G H C Q C + G + C C GY D + C + C CE+ C
Sbjct: 2249 DECEEGKHDCTEKQMEC-KNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRC 2307
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTC-----------SAQDKCALGTHGCQHI------CV 364
+N R GSY CEC +G+T + ++ C Q+ C +G+ + C
Sbjct: 2308 LNTR-GSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCD 2366
Query: 365 NDRTGSHHCECYEGYTLNADKKTC----------SVRDKCALGSHGCQH-ICVSDGAASY 413
R HCE A KK C + D+C + C++ CV+D SY
Sbjct: 2367 GGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVND-RGSY 2425
Query: 414 HCDCYPGYTLNEDKKTCSATEEARR 438
HC C GYT + +C E +
Sbjct: 2426 HCICKTGYTPDITGTSCVDLNECNQ 2450
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/256 (23%), Positives = 88/256 (34%), Gaps = 81/256 (31%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C + +CI++ +G C C G+ L +D + C ++ C T G IC+N
Sbjct: 573 MDECSIRNMCLNGMCINE-DGSFKCICKPGFQLASDGRYCKDINEC--ETPG---ICMNG 626
Query: 325 R----SGSYHCE----------------------CYEGY--------------------- 337
R GSY CE CY GY
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
Query: 338 ----TLNEDRKTCSAQD----------------------KCALGTHGCQH-ICVNDRTGS 370
E + C AQ+ +CAL C + IC N R G+
Sbjct: 687 STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLR-GT 745
Query: 371 HHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
+ C C GY +++ K C ++C L S C + + S+ C C G+ D KTC
Sbjct: 746 YKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTC 805
Query: 431 SATEEARRLVSTEDAC 446
+E C
Sbjct: 806 EDIDECESSPCINGVC 821
Score = 59.7 bits (143), Expect = 6e-09
Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 4/115 (3%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C G H+CQH C + G + C C QGY + C + C L+ H C ++
Sbjct: 2568 VDECE-GNHRCQHGC-QNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGASCHN 2624
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGY 379
GSY C C G+ + C ++C C + C N G + C C GY
Sbjct: 2625 TLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTE-GGYLCGCPPGY 2678
Score = 53.1 bits (126), Expect = 5e-07
Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 38/203 (18%)
Query: 263 CALDPCV-----LGTH----QCQHVCISDGE--GKHHCECSQGYT---LNADKKTCSALD 308
C+ D C+ +GTH C+ C++ G + C C+ G+T D +T
Sbjct: 129 CSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFT 188
Query: 309 RCALNTHGCEH-----ICVND-------RSGSYHCE--------CYEGYTLNEDRKTCSA 348
++ C+ +C R+ + CE C G+ N C
Sbjct: 189 --VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQD 246
Query: 349 QDKCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
D+C CQ C+N GS C+C G+ LN + C D+C+ C+ +
Sbjct: 247 VDECQAIPGLCQGGNCINT-VGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 408 DGAASYHCDCYPGYTLNEDKKTC 430
+ +SY C C PG+ + D C
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRC 328
Score = 51.2 bits (121), Expect = 2e-06
Identities = 52/216 (24%), Positives = 70/216 (32%), Gaps = 48/216 (22%)
Query: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
CV GT C ++ G CEC GY L+ C+ ++ C T CVN G
Sbjct: 1456 CVFGT--CHNL-----PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNT-PG 1507
Query: 328 SYHCECYEGYTLNEDRKTC---------------------SAQDKCALGTHGCQHICVND 366
SY C+C + LN R C + ++ +G C
Sbjct: 1508 SYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLG 1567
Query: 367 RTGSHHCECY---------------EGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAA 411
+ CE EG+ N D+C CQ +
Sbjct: 1568 KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFG 1627
Query: 412 SYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACG 447
S+ C C GY LNED + C E T CG
Sbjct: 1628 SFQCRCPTGYYLNEDTRVCDDVNEC----ETPGICG 1659
Score = 48.9 bits (115), Expect = 1e-05
Identities = 53/241 (21%), Positives = 80/241 (33%), Gaps = 74/241 (30%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDR--------------- 309
+D CV C S+ EG C C +G++L++ + C L
Sbjct: 2014 IDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSP 2073
Query: 310 -----------CALNTHG----CEHICVNDRSGSY----------------------HCE 332
CAL G CE +C + ++ C+
Sbjct: 2074 KSRNHSKQECCCALKGEGWGDPCE-LCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK 2132
Query: 333 ----CYEGYTLNED--------------RKTCSAQDKCALGTHGCQHICVNDRTGSHHCE 374
C G +N D C D+C++G + C + + G C
Sbjct: 2133 EPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVG-NPCGNGTCKNVIGGFECT 2191
Query: 375 CYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATE 434
C EG+ TC ++CA C CV+ SY C C GY L ED++ C +
Sbjct: 2192 CEEGFE-PGPMMTCEDINECAQNPLLCAFRCVNT-YGSYECKCPVGYVLREDRRMCKDED 2249
Query: 435 E 435
E
Sbjct: 2250 E 2250
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/192 (23%), Positives = 73/192 (38%), Gaps = 40/192 (20%)
Query: 291 CSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTC--- 346
C +GY+ C +D C + C++ +CVN R GS+ C+C G TL+ + C
Sbjct: 896 CGKGYS-RIKGTQCEDIDECEVFPGVCKNGLCVNTR-GSFKCQCPSGMTLDATGRICLDI 953
Query: 347 --------SAQDKCAL---GTHGCQHIC--VNDRTGSHHCE-------------CYEG-- 378
++C L G H C V G+ CE C G
Sbjct: 954 RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPG 1013
Query: 379 ---YTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
+ K ++C + C H + S+ C C G+ L+ +++ C+ +E
Sbjct: 1014 FATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDE 1073
Query: 436 ARRLVSTEDACG 447
R + D CG
Sbjct: 1074 CR---ISPDLCG 1082
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 28/132 (21%)
Query: 280 ISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYT 338
++ E K C +G+ N +D C C+ C+N GS+ C C GY
Sbjct: 1580 VNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINT-FGSFQCRCPTGYY 1638
Query: 339 LNEDRKTCSAQDKC-------------ALGTHGCQHICVNDR---TGSHHCE------CY 376
LNED + C ++C +G + C IC D G ++C CY
Sbjct: 1639 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTC--ICPPDYMQVNGGNNCMDMRRSLCY 1696
Query: 377 EGYTLNADKKTC 388
Y AD +TC
Sbjct: 1697 RNY--YADNQTC 1706
Score = 38.9 bits (89), Expect = 0.011
Identities = 47/214 (21%), Positives = 70/214 (32%), Gaps = 47/214 (21%)
Query: 271 GTHQCQHV---CISDGE-GKHHCECSQGYTLNADKKTCSALDRCALNTHG----CEHICV 322
G+ QH C++ G HC C +GY + TH CE C+
Sbjct: 112 GSRSIQHCNIRCMNGGSCSDDHCLCQKGY----------------IGTHCGQPVCESGCL 155
Query: 323 NDRS--GSYHCECYEGYTLNE-DRKTCSAQDKCALGTHGCQH-----ICVND-------R 367
N C C G+T + +R + + CQ +C R
Sbjct: 156 NGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGR 215
Query: 368 TGSHHCE--------CYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYP 419
H CE C G+ N C D+C CQ + S+ C C
Sbjct: 216 AWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPA 275
Query: 420 GYTLNEDKKTCSATEEARRLVSTEDACGCEATLA 453
G+ LNE + C +E + + C T++
Sbjct: 276 GHKLNEVSQKCEDIDECSTIPGICEGGECTNTVS 309
Score = 38.1 bits (87), Expect = 0.018
Identities = 38/143 (26%), Positives = 47/143 (32%), Gaps = 18/143 (12%)
Query: 280 ISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTL 339
I G K C CS G + C A VN C EG+
Sbjct: 1553 IGVGVSKASCCCSLGKAWGTPCEMCPA---------------VNTSEYKILCPGGEGFRP 1597
Query: 340 NEDRKTCSAQDKCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGS 398
N D+C CQ C+N GS C C GY LN D + C ++C
Sbjct: 1598 NPITVILEDIDECQELPGLCQGGKCINT-FGSFQCRCPTGYYLNEDTRVCDDVNECETPG 1656
Query: 399 HGCQHICVSDGAASYHCDCYPGY 421
C + +Y C C P Y
Sbjct: 1657 ICGPGTCYNT-VGNYTCICPPDY 1678
Score = 35.8 bits (81), Expect = 0.090
Identities = 20/80 (25%), Positives = 28/80 (35%), Gaps = 1/80 (1%)
Query: 258 FQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC 317
+Q C + L H C + G + C C G+ C ++ C C
Sbjct: 2600 YQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPC 2659
Query: 318 EHICVNDRSGSYHCECYEGY 337
+ C N G Y C C GY
Sbjct: 2660 SYGCSN-TEGGYLCGCPPGY 2678
Score = 33.9 bits (76), Expect = 0.34
Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 1/73 (1%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C CQ + G C C GY LN D + C ++ C C N
Sbjct: 1607 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYN- 1665
Query: 325 RSGSYHCECYEGY 337
G+Y C C Y
Sbjct: 1666 TVGNYTCICPPDY 1678
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 106 bits (264), Expect = 5e-23
Identities = 66/223 (29%), Positives = 87/223 (39%), Gaps = 47/223 (21%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C + + C + + G C C GYT + +C LD C+ + C +IC N
Sbjct: 2450 IDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNT 2509
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN------------------- 365
GSY C C GY L ED KTC D+C H CQ +CVN
Sbjct: 2510 E-GSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTA 2568
Query: 366 ---------------------DRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
+ GS CEC G++L+A C D+C G+H CQH
Sbjct: 2569 CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD-GNHRCQHG 2627
Query: 405 CVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACG 447
C + Y C C GY + C E S +ACG
Sbjct: 2628 C-QNILGGYRCGCPQGYIQHYQWNQCVDENEC----SNPNACG 2665
Score = 105 bits (262), Expect = 9e-23
Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
++ C L + C++ + G + C C+ GY D++ C+ +D C + GC+ C N
Sbjct: 1201 INECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNS 1260
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
GSY C C EGY L D ++C+ D+C C + G + C CY+G+ + D
Sbjct: 1261 E-GSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 1319
Query: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
KTC ++C L S+ C + S+ C C GY++ + C+ +E
Sbjct: 1320 MKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDE 1370
Score = 102 bits (255), Expect = 6e-22
Identities = 61/172 (35%), Positives = 87/172 (50%), Gaps = 15/172 (8%)
Query: 265 LDPCVLGTHQCQ--HVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
LD C GTHQC C++ G + C CS+G+T D TCS +D CA N + CE+
Sbjct: 1409 LDECSNGTHQCSINAQCVNT-PGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQC 1465
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICV----NDRTGSHHCECYEG 378
+ G+Y CEC G+T D ++C D+C+ Q+ICV N+ G HC C +G
Sbjct: 1466 LNVPGAYRCECEMGFTPASDSRSCQDIDECSF-----QNICVFGTCNNLPGMFHCICDDG 1520
Query: 379 YTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
Y L+ C+ D+CA + +CV+ Y C+C P + LN C
Sbjct: 1521 YELDRTGGNCTDIDECADPINCVNGLCVNT-PGRYECNCPPDFQLNPTGVGC 1571
Score = 102 bits (254), Expect = 8e-22
Identities = 49/161 (30%), Positives = 79/161 (49%), Gaps = 2/161 (1%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C++ C C ++ EG + C CS+GY L D ++C+ +D C N C+ +
Sbjct: 1243 IDECMIMNGGCDTQC-TNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTN 1301
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
G Y C CY+G+ + D KTC ++C L ++ C + GS C C GY++
Sbjct: 1302 IPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKG 1361
Query: 385 KKTCSVRDKCALGSHGC-QHICVSDGAASYHCDCYPGYTLN 424
C+ D+C +G+H C H + S+ C C G+ N
Sbjct: 1362 TTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGN 1402
Score = 100 bits (248), Expect = 4e-21
Identities = 61/229 (26%), Positives = 89/229 (38%), Gaps = 49/229 (21%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVN- 323
LD C C ++C + EG + C C +GY L D KTC LD C H C+ +CVN
Sbjct: 2492 LDECSQSPKPCNYIC-KNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNT 2550
Query: 324 ---------------------------------------DRSGSYHCECYEGYTLNEDRK 344
+ GS+ CEC G++L+
Sbjct: 2551 LGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGL 2610
Query: 345 TCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHI 404
C D+C G H CQH C N G + C C +GY + C ++C+ + C
Sbjct: 2611 NCEDVDECD-GNHRCQHGCQNI-LGGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSA 2667
Query: 405 CVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDAC--GCEAT 451
+ SY C C G++ ++ C E S+++ C GC T
Sbjct: 2668 SCYNTLGSYKCACPSGFSFDQFSSACHDVNECS---SSKNPCNYGCSNT 2713
Score = 97.1 bits (240), Expect = 3e-20
Identities = 56/185 (30%), Positives = 90/185 (48%), Gaps = 8/185 (4%)
Query: 254 LSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
++S +T ++ C L ++ C + +G C C GY++ C+ +D C +
Sbjct: 1315 MASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIG 1374
Query: 314 THGCE-HICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGC--QHICVNDRTGS 370
H C+ H + GS+ C C EG+ N + C D+C+ GTH C CVN GS
Sbjct: 1375 AHNCDMHASCLNIPGSFKCSCREGWIGNGIK--CIDLDECSNGTHQCSINAQCVN-TPGS 1431
Query: 371 HHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
+ C C EG+T D TCS D+CA + C++ + +Y C+C G+T D ++C
Sbjct: 1432 YRCACSEGFT--GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSC 1489
Query: 431 SATEE 435
+E
Sbjct: 1490 QDIDE 1494
Score = 95.9 bits (237), Expect = 7e-20
Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 6/174 (3%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLN-ADKKTCSALDRCALNTHGCEH-ICV 322
+D C + C + G CEC +GY K C +D C N C CV
Sbjct: 1116 IDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCV 1175
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH-ICVNDRTGSHHCECYEGYTL 381
N GS+ C+C G+ L+ R+ C ++C+L + C++ CVN G++ C C GY
Sbjct: 1176 NTE-GSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVN-MIGTYQCSCNPGYQA 1233
Query: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
D++ C+ D+C + + GC C ++ SY C C GY L D ++C+ +E
Sbjct: 1234 TPDRQGCTDIDECMIMNGGCDTQC-TNSEGSYECSCSEGYALMPDGRSCADIDE 1286
Score = 91.7 bits (226), Expect = 1e-18
Identities = 48/154 (31%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 285 GKHHCECSQGYTLNADKKTCSALDRCALNTHGC-EHICVNDRSGSYHCECYEGYTLN-ED 342
G C C+ G+ L+ +++ C+ +D C ++ C ICVN GS+ CEC+EGY
Sbjct: 1094 GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNT-PGSFECECFEGYESGFMM 1152
Query: 343 RKTCSAQDKCALGTHGCQ-HICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGC 401
K C D+C C+ CVN GS C+C G+ L+ ++ C ++C+L + C
Sbjct: 1153 MKNCMDIDECERNPLLCRGGTCVNTE-GSFQCDCPLGHELSPSREDCVDINECSLSDNLC 1211
Query: 402 QHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
++ + +Y C C PGY D++ C+ +E
Sbjct: 1212 RNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDE 1245
Score = 87.0 bits (214), Expect = 3e-17
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 11/172 (6%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-IC 321
C +PC G C++ G ++C+C G+ K+ C +D C N C++ C
Sbjct: 539 CTSNPCTNGD------CVNT-PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRC 591
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTL 381
VN GS+ C C G+ L D K C D+C +C+N+ GS C C G+ L
Sbjct: 592 VN-TDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINE-DGSFKCICKPGFVL 649
Query: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSAT 433
+ + C+ D+C C+ + S+ CDC PG + D + C T
Sbjct: 650 APNGRYCTDVDECQTPGICMNGHCI-NSEGSFRCDCPPGLAVGMDGRVCVDT 700
Score = 86.3 bits (212), Expect = 6e-17
Identities = 49/173 (28%), Positives = 78/173 (45%), Gaps = 6/173 (3%)
Query: 265 LDPCVLGTHQCQHV--CISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
+D C G + CQ CI+ G + CEC+ G+ L+ + C + C + C H
Sbjct: 1851 IDECSNGDNLCQRNADCINS-PGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLC 1908
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
D GSY C C+ G+ ++D+ C D+C H C + + GS++C CY G+ L
Sbjct: 1909 VDLQGSYQCICHNGFKASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFELT 1966
Query: 383 ADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
+ + + + C++ + S+ C C GY L D K C T E
Sbjct: 1967 HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNE 2019
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/208 (28%), Positives = 81/208 (38%), Gaps = 19/208 (9%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
C P + QC + +G CEC GY L+ C D C++ C
Sbjct: 2175 CLESPGICSNGQCINT-----DGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCT 2229
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLN 382
N GS+ C C EG+ C ++CA C C+N GS+ C C GY L
Sbjct: 2230 N-VIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLCAFRCMN-TFGSYECTCPIGYALR 2286
Query: 383 ADKKTCSVRDKCALGSHGCQH--ICVSDGAASYHCDCYPGYTLNEDKKTCSATEEAR--- 437
D+K C D+CA G H C+ + + ++ C C PG D + C E R
Sbjct: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKP 2346
Query: 438 ------RLVSTEDACGCEATLAFQDKVS 459
R V+ + CE FQ S
Sbjct: 2347 GICENGRCVNIIGSYRCECNEGFQSSSS 2374
Score = 85.1 bits (209), Expect = 1e-16
Identities = 47/151 (31%), Positives = 73/151 (48%), Gaps = 7/151 (4%)
Query: 278 VCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH--ICVNDRSGSYHCECYE 335
VCI+ G CEC G++ N C +D C+ + C+ C+N GSY CEC
Sbjct: 1823 VCINQ-IGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINS-PGSYRCECAA 1880
Query: 336 GYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCA 395
G+ L+ + C +++C + C H D GS+ C C+ G+ + D+ C D+C
Sbjct: 1881 GFKLSPN-GACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE 1939
Query: 396 LGSHGCQHICVSDGAASYHCDCYPGYTLNED 426
H C + + SY+C CYPG+ L +
Sbjct: 1940 --RHPCGNGTCKNTVGSYNCLCYPGFELTHN 1968
Score = 81.6 bits (200), Expect = 1e-15
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 7/168 (4%)
Query: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDR 325
D C +G + C + ++ G C C++G+ C ++ CA N C C+N
Sbjct: 2215 DECSIG-NPCGNGTCTNVIGSFECNCNEGFE-PGPMMNCEDINECAQNPLLCAFRCMNT- 2271
Query: 326 SGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH---ICVNDRTGSHHCECYEGYTLN 382
GSY C C GY L ED+K C D+CA G H C+ +C N G+ C C G
Sbjct: 2272 FGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKN-LIGTFMCICPPGMARR 2330
Query: 383 ADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
D + C ++C C++ + SY C+C G+ + C
Sbjct: 2331 PDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC 2378
Score = 81.3 bits (199), Expect = 2e-15
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 10/160 (6%)
Query: 263 CALDPCVLGTHQ-CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHIC 321
C P + G CQ+ G CEC +G++L+A C +D C N H C+H C
Sbjct: 2575 CGSQPSLCGAKGICQNT-----PGSFSCECQRGFSLDATGLNCEDVDECDGN-HRCQHGC 2628
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTL 381
N G Y C C +GY + C +++C+ + C + GS+ C C G++
Sbjct: 2629 QN-ILGGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSASCYNTLGSYKCACPSGFSF 2686
Query: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGY 421
+ C ++C+ + C + C S+ Y C C PGY
Sbjct: 2687 DQFSSACHDVNECSSSKNPCNYGC-SNTEGGYLCGCPPGY 2725
Score = 80.9 bits (198), Expect = 2e-15
Identities = 48/154 (31%), Positives = 77/154 (50%), Gaps = 10/154 (6%)
Query: 287 HHCECSQGYTLNADKKTCSALDRCALN--THGCEHICVNDRSGSYHCECYEGYTLNEDRK 344
+ CEC+ GY +A+ C +D C N T+G CVN GSY+C+C+ G+ ++
Sbjct: 517 YRCECNMGYKQDANGD-CIDVDECTSNPCTNGD---CVNT-PGSYYCKCHAGFQRTPTKQ 571
Query: 345 TCSAQDKCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQH 403
C D+C C++ CVN GS C C G+ L D K C D+C +
Sbjct: 572 ACIDIDECIQNGVLCKNGRCVNT-DGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNG 630
Query: 404 ICVSDGAASYHCDCYPGYTLNEDKKTCSATEEAR 437
+C+++ S+ C C PG+ L + + C+ +E +
Sbjct: 631 MCINEDG-SFKCICKPGFVLAPNGRYCTDVDECQ 663
Score = 80.1 bits (196), Expect = 4e-15
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 2/159 (1%)
Query: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
C+ + C H D +G + C C G+ + D+ C +D C H C + + G
Sbjct: 1896 CLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDEC--ERHPCGNGTCKNTVG 1953
Query: 328 SYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKT 387
SY+C CY G+ L + + + C++ + GS C C EGY L D K
Sbjct: 1954 SYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKN 2013
Query: 388 CSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNED 426
C ++C C + S+ C C PGY + +
Sbjct: 2014 CIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSE 2052
Score = 76.6 bits (187), Expect = 5e-14
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 6/153 (3%)
Query: 289 CECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTCS 347
C G+T + +D C C + +C+N + GS+ CEC G++ N+ C
Sbjct: 1791 CGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCIN-QIGSFRCECPTGFSYNDLLLVCE 1849
Query: 348 AQDKCALGTHGCQH--ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHIC 405
D+C+ G + CQ C+N GS+ CEC G+ L+ + C R++C + C H
Sbjct: 1850 DIDECSNGDNLCQRNADCINS-PGSYRCECAAGFKLSPN-GACVDRNECLEIPNVCSHGL 1907
Query: 406 VSDGAASYHCDCYPGYTLNEDKKTCSATEEARR 438
D SY C C+ G+ ++D+ C +E R
Sbjct: 1908 CVDLQGSYQCICHNGFKASQDQTMCMDVDECER 1940
Score = 76.3 bits (186), Expect = 6e-14
Identities = 50/191 (26%), Positives = 84/191 (43%), Gaps = 9/191 (4%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-IC 321
C +P CQ C + + H CS G + D + ++ CAL+ C + IC
Sbjct: 729 CCANPDYGFGEPCQP-CPAKNSAEFHGLCSSGVGITVDGRD---INECALDPDICANGIC 784
Query: 322 VNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTL 381
N R GSY C C GY + + C D+C + C + + GS+ C C GY
Sbjct: 785 ENLR-GSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVF 843
Query: 382 NADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVS 441
+ +TC ++C S+ C + + S++C+C PG L+ C + + ++
Sbjct: 844 RTETETCEDINECE--SNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLN 901
Query: 442 TEDACGCEATL 452
+D+ CE +
Sbjct: 902 IQDS-RCEVNI 911
Score = 69.3 bits (168), Expect = 7e-12
Identities = 52/172 (30%), Positives = 72/172 (41%), Gaps = 14/172 (8%)
Query: 266 DPCVLGTHQCQHVCISDGEGKHHCECSQGY-TLNADKKTCSALDRCALNTHGCEH-ICVN 323
DPC L C D E C G+ T+ + T ++ C + C + C+N
Sbjct: 2138 DPCEL--------CPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCIN 2189
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNA 383
GS+ CEC GY L+ C D+C++G C N GS C C EG+
Sbjct: 2190 T-DGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTN-VIGSFECNCNEGFE-PG 2246
Query: 384 DKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
C ++CA C C++ SY C C GY L ED+K C +E
Sbjct: 2247 PMMNCEDINECAQNPLLCAFRCMNT-FGSYECTCPIGYALREDQKMCKDLDE 2297
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/229 (21%), Positives = 83/229 (36%), Gaps = 66/229 (28%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
CALDP + C+++ G + C C+ GY +A + C +D C +N C++
Sbjct: 772 CALDPDICANGICENL-----RGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLC 826
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCA------------LGTHGCQH--------- 361
+ GSY C C GY + +TC ++C LG+ C+
Sbjct: 827 RNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSST 886
Query: 362 --ICVNDRTGS-------HHCEC-YEGYTLNAD--------------------------- 384
IC++ G+ CE G TL ++
Sbjct: 887 GLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLA 946
Query: 385 ---KKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTC 430
TC ++C + C + + S+HC+C G TL+ + C
Sbjct: 947 RIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 995
Score = 64.3 bits (155), Expect = 2e-10
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Query: 307 LDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGC-QHICVN 365
++ C C + + GS+ C C G+ L+ + + C+ D+C + C ICVN
Sbjct: 1074 INECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVN 1133
Query: 366 DRTGSHHCECYEGYTLN-ADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLN 424
GS CEC+EGY K C D+C C+ + S+ CDC G+ L+
Sbjct: 1134 T-PGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1192
Query: 425 EDKKTC 430
++ C
Sbjct: 1193 PSREDC 1198
Score = 62.8 bits (151), Expect = 7e-10
Identities = 51/208 (24%), Positives = 79/208 (37%), Gaps = 39/208 (18%)
Query: 260 ETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDR---------- 309
E C P + +C ++ G + CEC++G+ ++ C LD
Sbjct: 2339 ENECRTKPGICENGRCVNII-----GSYRCECNEGFQSSSSGTEC--LDNRQGLCFAEVL 2391
Query: 310 ---CALNTHG------CEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQ----------D 350
C + + E C R + CE + +K C D
Sbjct: 2392 QTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDID 2451
Query: 351 KCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDG 409
+C + + C + C+N GS C C GYT + +C D+C+ C +IC +
Sbjct: 2452 ECKVMPNLCTNGQCINTM-GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYIC-KNT 2509
Query: 410 AASYHCDCYPGYTLNEDKKTCSATEEAR 437
SY C C GY L ED KTC +E +
Sbjct: 2510 EGSYQCSCPRGYVLQEDGKTCKDLDECQ 2537
Score = 58.5 bits (140), Expect = 1e-08
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
Query: 317 CEH---ICVNDRS----GSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH-ICVNDRT 368
C+H +C+N R SY CEC GY + C D+C ++ C + CVN
Sbjct: 498 CKHHANLCLNGRCIPTVSSYRCECNMGYK-QDANGDCIDVDECT--SNPCTNGDCVNT-P 553
Query: 369 GSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKK 428
GS++C+C+ G+ K+ C D+C C++ + S+ C C G+ L D K
Sbjct: 554 GSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGK 613
Query: 429 TCSATEE 435
C +E
Sbjct: 614 NCVDHDE 620
Score = 53.1 bits (126), Expect = 5e-07
Identities = 48/203 (23%), Positives = 68/203 (33%), Gaps = 43/203 (21%)
Query: 268 CVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSG 327
CV GT C ++ G HC C GY L+ C+ +D CA + +CVN G
Sbjct: 1501 CVFGT--CNNL-----PGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNT-PG 1552
Query: 328 SYHCECYEGYTLNEDRKTC--------------------SAQDKCALGTHGCQHICVNDR 367
Y C C + LN C S + +G C +
Sbjct: 1553 RYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGK 1612
Query: 368 TGSHHCECY---------------EGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAAS 412
+ CE EG+ N D+C CQ + S
Sbjct: 1613 AWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGS 1672
Query: 413 YHCDCYPGYTLNEDKKTCSATEE 435
+ C+C GY L+ED + C +E
Sbjct: 1673 FQCECPQGYYLSEDTRICEDIDE 1695
Score = 49.3 bits (116), Expect = 8e-06
Identities = 50/203 (24%), Positives = 76/203 (37%), Gaps = 38/203 (18%)
Query: 263 CALDPC-----VLGTH----QCQHVCISDGE--GKHHCECSQGYT---LNADKKTCSALD 308
CA D C +GT+ C++ C + G G + C C G+T D +T
Sbjct: 159 CADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFT 218
Query: 309 RCALNTHGCEH-----ICVND-------RSGSYHCE--------CYEGYTLNEDRKTCSA 348
+ +N C+ +C R+ + CE C G+ N C
Sbjct: 219 Q--VNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQD 276
Query: 349 QDKCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
D+C CQ C+N GS C C G+ + + C D+C++ C+ S
Sbjct: 277 VDECQAIPGICQGGNCINT-VGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECS 335
Query: 408 DGAASYHCDCYPGYTLNEDKKTC 430
+ SY C C GY + D C
Sbjct: 336 NTVGSYFCVCPRGYVTSTDGSRC 358
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/189 (21%), Positives = 73/189 (38%), Gaps = 23/189 (12%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCS--ALDRCALNTHGCEHICV 322
++ C + C + + +G HCEC +G TL+ + C +++C L E C+
Sbjct: 956 VNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD--EDECI 1013
Query: 323 NDRSGSYH---CECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGY 379
+ G + C C G + + C GT + +C ++ + G
Sbjct: 1014 HPVPGKFRMDACCCAVGAAWGTECEECPKP-----GTKEYETLCPRGAGFANRGDVLTGR 1068
Query: 380 TLNADKKTCSV-RDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARR 438
D C C G C++ S+ C C G+ L+ +++ C+ +E R
Sbjct: 1069 PFYKDINECKAFPGMCTYGK--CRNTI-----GSFKCRCNSGFALDMEERNCTDIDECR- 1120
Query: 439 LVSTEDACG 447
+ D CG
Sbjct: 1121 --ISPDLCG 1127
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/162 (22%), Positives = 52/162 (32%), Gaps = 14/162 (8%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C CQ + G CEC QGY L+ D + C +D C + C +
Sbjct: 1651 IDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYN 1710
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNAD 384
G+Y C C Y C K C G+ C N
Sbjct: 1711 TLGNYTCICPPEYMQVNGGHNCMDMRK---------SFCYRSYNGT---TCENELPFNVT 1758
Query: 385 KKTCSVRDKCALGSHGCQHICVSDGAASYH--CDCYPGYTLN 424
K+ C + C + G A + C PG+T +
Sbjct: 1759 KRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFD 1800
Score = 42.7 bits (99), Expect = 7e-04
Identities = 23/85 (27%), Positives = 34/85 (40%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVND 324
+D C CQ + G C C G+ + + C +D C++ CE ++
Sbjct: 277 VDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSN 336
Query: 325 RSGSYHCECYEGYTLNEDRKTCSAQ 349
GSY C C GY + D C Q
Sbjct: 337 TVGSYFCVCPRGYVTSTDGSRCIDQ 361
Score = 37.7 bits (86), Expect = 0.024
Identities = 46/208 (22%), Positives = 70/208 (33%), Gaps = 46/208 (22%)
Query: 274 QCQHVCISDGE-GKHHCECSQGYT-LNADKKTCSALDRCALNTHGCEH--ICVNDRSGSY 329
QC C++ G HC+C +GY + C +GC++ C+ G
Sbjct: 148 QCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCE---------NGCQNGGRCI----GPN 194
Query: 330 HCECYEGYT---LNEDRKT--CSAQDKCALGTHGCQH-----ICVND-------RTGSHH 372
C C G+T D +T C Q + CQ +C R H
Sbjct: 195 RCACVYGFTGPQCERDYRTGPCFTQ----VNNQMCQGQLTGIVCTKTLCCATIGRAWGHP 250
Query: 373 CE--------CYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLN 424
CE C G+ N C D+C CQ + S+ C C G+ +
Sbjct: 251 CEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQS 310
Query: 425 EDKKTCSATEEARRLVSTEDACGCEATL 452
E + C +E + + C T+
Sbjct: 311 ETTQKCEDIDECSIIPGICETGECSNTV 338
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 101 bits (251), Expect = 2e-21
Identities = 112/450 (24%), Positives = 176/450 (39%), Gaps = 77/450 (17%)
Query: 11 PGLLLLLWPLLLLPSAAP----DPVARPGFRRLETRGPGGSPGRRPSPAAP-DGAPASGT 65
P L W L L+ A P FR PG +PG P+P AP D A S
Sbjct: 3 PRLAFCCWGLALVSGWATFQQMSPSRNFSFRLFPETAPG-APGSIPAPPAPGDEAAGSRV 61
Query: 66 SEPGRA--RGAGVCK--SRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTR 121
G+A R + + S L+LVF++D S SV + F FV +++ + P TR
Sbjct: 62 ERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATR 121
Query: 122 VAVVNYASTVKIEFQLQAYTDKQSLKQAVGRI---TPLSTGTMSGLAIQTAMDEAFTVEA 178
VA+V ++S + ++ + +++ + + P + G + A +A +
Sbjct: 122 VAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILL 181
Query: 179 GAREPSSNIPKVAIIVTDGRPQ-DQVNEVAARAQASGIELYAVGVDRADMASLKMMASEP 237
ARE N KV ++TDG +AA + SG+E++ G+ + ++ L MAS P
Sbjct: 182 HARE---NSTKVVFLITDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTP 238
Query: 238 LEEHVFYVETYGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDG----EGKHHCECSQ 293
EEH + + ++ E L+ R H + G + HC
Sbjct: 239 KEEHCYLLHSFEEFEALARR-----------------ALHEDLPSGSFIQDDMVHC---- 277
Query: 294 GYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCA 353
Y + K C + C TH +G + C C +GY + C+A C
Sbjct: 278 SYLCDEGKDCCDRMGSCKCGTH----------TGHFECICEKGYYGKGLQYECTA---CP 324
Query: 354 LGTH----------GC------QHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCAL- 396
GT+ C H T C C EGY A +TC + AL
Sbjct: 325 SGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGY--RASGQTCELVHCPALK 382
Query: 397 ---GSHGCQHICVSDGAASYHCDCYPGYTL 423
+ Q+ C + A+ C+PG+ L
Sbjct: 383 PPENGYFIQNTCNNHFNAACGVRCHPGFDL 412
Score = 47.4 bits (111), Expect = 3e-05
Identities = 53/192 (27%), Positives = 75/192 (39%), Gaps = 34/192 (17%)
Query: 239 EEHVFYVETYGVIEKLSSRFQETF--CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYT 296
EE V + G I+K + F C +PC + CQ + G G + C C GYT
Sbjct: 1171 EESVVPPASLGHIKKRHEISSQVFHECFFNPCH-NSGTCQQL----GRG-YVCLCPLGYT 1224
Query: 297 ---LNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYT---LNEDRKTCSAQD 350
D CS L LN C+ D G + CEC GYT E+ CS+
Sbjct: 1225 GLKCETDIDECSPLP--CLNNGVCK-----DLVGEFICECPSGYTGQRCEENINECSSSP 1277
Query: 351 KCALGTHGCQHICVNDRTGSHHCECYEGYT-LNADKKTCSVRDKCALGSHGCQHICVSDG 409
G ICV D + C C +G+ L+ + + + L + C+ D
Sbjct: 1278 CLNKG------ICV-DGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCE-----DQ 1325
Query: 410 AASYHCDCYPGY 421
+ C C PG+
Sbjct: 1326 VGGFLCKCPPGF 1337
Score = 47.4 bits (111), Expect = 3e-05
Identities = 51/216 (23%), Positives = 86/216 (39%), Gaps = 27/216 (12%)
Query: 268 CVLGTHQCQHV-CISDGE-----GKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHIC 321
C +C + C+++G G+ CEC GYT ++ ++ C+ + + IC
Sbjct: 1228 CETDIDECSPLPCLNNGVCKDLVGEFICECPSGYT---GQRCEENINECSSSPCLNKGIC 1284
Query: 322 VNDRSGSYHCECYEGYT-LNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYT 380
V+ +G Y C C +G+ L+ + + Q L C+ D+ G C+C G+
Sbjct: 1285 VDGVAG-YRCTCVKGFVGLHCETEVNECQSNPCLNNAVCE-----DQVGGFLCKCPPGFL 1338
Query: 381 LNADKKTCSVRDKCALGSHGCQH-ICVSDGAASYHCDCYPGYT-----LNEDKKTCSATE 434
K D+C S C++ DGA S+ C C G+T LN ++ +
Sbjct: 1339 GTRCGKNV---DECL--SQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCR 1393
Query: 435 EARRLVSTEDACGCEATLAFQDKVSSYLQRLNTKLD 470
V ++ C+ F K Q LD
Sbjct: 1394 NQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLD 1429
Score = 44.3 bits (103), Expect = 3e-04
Identities = 49/179 (27%), Positives = 71/179 (39%), Gaps = 27/179 (15%)
Query: 272 THQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHC 331
T+QC + G+ + C + + N +C +D CA+ + EH + GSY C
Sbjct: 1713 TYQCNNGYYLLGDSRMFCTDNGSW--NGVSPSCLDVDECAVGSDCSEHASCLNVDGSYIC 1770
Query: 332 ECYEGYTLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHC--ECYEGYTL-NADKKT 387
C YT D K C+ KC A G H T C EGY L K T
Sbjct: 1771 SCVPPYT--GDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKIT 1828
Query: 388 CSVR---------------DKCALGSHGC-QHICVSDGA-ASYHCDCYPGYTLNEDKKT 429
C K A+ +GC + + + G+ +Y C+ GYTL DK++
Sbjct: 1829 CLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCN--KGYTLAGDKES 1885
Score = 36.6 bits (83), Expect = 0.053
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 369 GSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKK 428
G C + + N +C D+CA+GS +H + SY C C P YT D K
Sbjct: 1724 GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYT--GDGK 1781
Query: 429 TCS 431
C+
Sbjct: 1782 NCA 1784
Score = 36.2 bits (82), Expect = 0.069
Identities = 44/196 (22%), Positives = 65/196 (33%), Gaps = 41/196 (20%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCAL-----NTHGCEH 319
+D C +G+ +H + +G + C C YT D K C+ +C N H
Sbjct: 1746 VDECAVGSDCSEHASCLNVDGSYICSCVPPYT--GDGKNCAEPIKCKAPGNPENGHSSGE 1803
Query: 320 ICVNDRSGSYHCE------------CYEGYTLNEDRKTCSAQD--KCALGTHGCQHICVN 365
I ++ C+ C E N C A K A+ +GC
Sbjct: 1804 IYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAF 1863
Query: 366 DRTGSHHCECYEGYTLNADKK-TCSVRDKCALGSHGCQHICVSD---------------- 408
C +GYTL DK+ +C + C+ + S
Sbjct: 1864 TFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTY 1923
Query: 409 -GAASYHCDCYPGYTL 423
ASY CD GY+L
Sbjct: 1924 LSTASYSCD--TGYSL 1937
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 100 bits (249), Expect = 3e-21
Identities = 55/194 (28%), Positives = 103/194 (53%), Gaps = 5/194 (2%)
Query: 75 GVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIE 134
G ++ D+ F+ID S S++ +F ++K F+ + + IGP RV VV Y+ ++E
Sbjct: 434 GCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVE 493
Query: 135 FQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIV 194
F + Y++ L++A+ I L+ GT +G A+ + ++ G ++ S +P I++
Sbjct: 494 FYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQ---IIKNGMKDRMSKVPCYLIVL 550
Query: 195 TDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKL 254
TDG D+V E A R +A I ++AVG+ A+ L+ +A + EE V + + + ++ +
Sbjct: 551 TDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGK--EERVSFGQNFDALKSI 608
Query: 255 SSRFQETFCALDPC 268
+ CA C
Sbjct: 609 KNEVVREICAEKGC 622
Score = 99.8 bits (247), Expect = 5e-21
Identities = 59/206 (28%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
C+ D++F++DSS S+ F K+K F+ ++ + IG T++ VV ++ K EFQ
Sbjct: 622 CEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQ 681
Query: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
L Y +Q + A+ R++ ++ GT++G A+ + + FT GAR K I++TD
Sbjct: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKAL-NFVGQYFTHSKGAR---LGAKKFLILITD 737
Query: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
G QD V + A + + +++VGV A+ + L+ ++ + VF+VE + ++ L
Sbjct: 738 GVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGD--SSLVFHVENFDHLKALER 795
Query: 257 RFQETFCALDPCVLGTHQCQHVCISD 282
+ CAL H C+ + + D
Sbjct: 796 KLIFRVCAL-------HDCKRITLLD 814
Score = 77.4 bits (189), Expect = 3e-14
Identities = 50/207 (24%), Positives = 100/207 (48%), Gaps = 6/207 (2%)
Query: 82 LDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYT 141
LD+VF++D S S++ + ++ D+G + + Y+ I F L Y+
Sbjct: 813 LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYS 872
Query: 142 DKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDG--RP 199
++ ++ + + + T + A++ A + FT E G+R N+ ++ I++TDG
Sbjct: 873 NRSAIIENLRKRRDTGGNTYTAKALKHA-NALFTEEHGSR-IKQNVKQMLIVITDGESHD 930
Query: 200 QDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQ 259
DQ+N+ A + GI ++AVGV +A+ L+ MA + + YV+ + ++ + + Q
Sbjct: 931 HDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGN--KNNTIYVDNFDKLKDVFTLVQ 988
Query: 260 ETFCALDPCVLGTHQCQHVCISDGEGK 286
E C P V + + + DG +
Sbjct: 989 ERMCTEAPEVCHLQEADVIFLCDGSDR 1015
Score = 75.5 bits (184), Expect = 1e-13
Identities = 43/154 (27%), Positives = 79/154 (51%), Gaps = 2/154 (1%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
D+VF++DSS + P F VKTF++++I++L I RVA+ Y+ EF L +
Sbjct: 30 DVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKG 89
Query: 143 KQSLKQAVGRITPLSTGTMS-GLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQD 201
+ + + + G++ G A+Q A F+ R+ P + +++ +D
Sbjct: 90 RSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRD-RKQFPPILVVLASAESED 148
Query: 202 QVNEVAARAQASGIELYAVGVDRADMASLKMMAS 235
+V E + Q G+++ +VGV +A +LK MA+
Sbjct: 149 EVEEASKALQKDGVKIISVGVQKASEENLKAMAT 182
Score = 69.3 bits (168), Expect = 7e-12
Identities = 39/176 (22%), Positives = 92/176 (52%), Gaps = 2/176 (1%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
DLVF++D S ++TF+ I ++D+ R+ +++Y+++ K L++ T
Sbjct: 236 DLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294
Query: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
+ +Q + ++ + +G AI + F+ G+R + +P++A++VT D+
Sbjct: 295 QSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRR-AQGVPQIAVLVTHRPSDDE 353
Query: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRF 258
V++ A + + ++A+ + A+ L+ + S P E+ + +++Y +E S++F
Sbjct: 354 VHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKF 409
Score = 57.8 bits (138), Expect = 2e-08
Identities = 46/182 (25%), Positives = 81/182 (44%), Gaps = 26/182 (14%)
Query: 82 LDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPA------DTRVAVVNYA------- 128
+D+ F+ID+S+ V EF +VK F++ ++D I P RVAV++Y+
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
Query: 129 ---STVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSS 185
V +EF L Y +K + L+ G A+Q +D F P+
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVF-----VGTPNL 2404
Query: 186 NIPKVAIIVTDGR----PQDQVNEVAARAQASGIELYAVGV-DRADMASLKMMASEPLEE 240
KV +++ G +D + V+ RA+ G ++ + + L+ +AS PL+
Sbjct: 2405 RKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDH 2464
Query: 241 HV 242
H+
Sbjct: 2465 HL 2466
Score = 55.5 bits (132), Expect = 1e-07
Identities = 45/180 (25%), Positives = 82/180 (45%), Gaps = 24/180 (13%)
Query: 82 LDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLD------IGPADTRVAVVNYA------- 128
+D+VF+ID+SR++ EF VK VS +ID + I + R+A+++Y+
Sbjct: 1962 MDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRR 2021
Query: 129 --STVKIEFQLQAYTDKQSLKQAV-GRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSS 185
TVK EF Y ++ +K + L+ G A+ + F P
Sbjct: 2022 KMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLF-----PETPYL 2076
Query: 186 NIPKVAIIVTDGRPQDQ---VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHV 242
KV +V+ G ++ V +A RA+ G ++ + + ++ +AS PL++H+
Sbjct: 2077 RKHKVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHL 2136
Score = 53.5 bits (127), Expect = 4e-07
Identities = 32/147 (21%), Positives = 67/147 (45%), Gaps = 2/147 (1%)
Query: 76 VCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEF 135
VC + D++F+ D S V +F + TF+S +ID DI ++ + + S +
Sbjct: 998 VCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSII 1057
Query: 136 QLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVT 195
+L+ K K + ++ A++ + F + AG R ++ +P+ +++T
Sbjct: 1058 ELKNSLTKTQWKTQIQNVSKSGGFPRIDFALK-KVSNMFNLHAGGRR-NAGVPQTLVVIT 1115
Query: 196 DGRPQDQVNEVAARAQASGIELYAVGV 222
G P+ V + + GI + +G+
Sbjct: 1116 SGDPRYDVADAVKTLKDLGICVLVLGI 1142
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/151 (23%), Positives = 67/151 (44%), Gaps = 18/151 (11%)
Query: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIG----PADTRVAVVNYASTVK 132
C + P +LVF +D+S V F K + ++ I++ L+I P RVA+V+Y S
Sbjct: 1752 CPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTS 1811
Query: 133 IEFQLQAYTDKQSLKQAVGRI------TPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSN 186
+ Y K+ L Q + +I P G + + AGA N
Sbjct: 1812 YLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTY---AGA-----N 1863
Query: 187 IPKVAIIVTDGRPQDQVNEVAARAQASGIEL 217
+ +VA+ ++G+ + + + A + S +++
Sbjct: 1864 VRRVAVFFSNGQTASRSSIITATMEFSALDI 1894
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 100 bits (249), Expect = 3e-21
Identities = 61/165 (36%), Positives = 82/165 (49%), Gaps = 12/165 (7%)
Query: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECY 334
CQH C + G + C C+ G+ L AD K C ++ C C C N GSY C C
Sbjct: 913 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQECANIY-GSYQCYCR 968
Query: 335 EGYTLNEDRKTCSAQDKCALGTH-GCQHICVNDRTGSHHCECYE-GYTLNADKKTCSVRD 392
+GY L ED TC+ D+CA G C C+N GS+ C C E GYT+ A+ ++C D
Sbjct: 969 QGYQLAEDGHTCTDIDECAQGAGILCTFRCLN-VPGSYQCACPEQGYTMTANGRSCKDVD 1027
Query: 393 KCALGSHGCQHI-CVSDGAASYHC---DCYPGYTLNEDKKTCSAT 433
+CALG+H C + S+ C +C P Y + K C T
Sbjct: 1028 ECALGTHNCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKCERT 1071
Score = 82.8 bits (203), Expect = 6e-16
Identities = 62/213 (29%), Positives = 92/213 (43%), Gaps = 33/213 (15%)
Query: 265 LDPCVLGTHQCQ--HVCISDGEGKHHCE----CSQGYTLNADKKTCSALDRCALNTHGCE 318
+D C +GTH CQ +C + +G +C+ C G+ L + C ++ C + C
Sbjct: 765 VDECAMGTHTCQPGFLC-QNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCR 822
Query: 319 --HICVNDRSGSYHCE-----CYEGYTLNEDRKTCSAQDKCALGTHGC--QHICVNDRTG 369
C+N GSY C+ C GY ++D C ++C G H C +C N G
Sbjct: 823 PGFSCIN-TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN-LPG 880
Query: 370 SHHCECYEGYTLNADKKTCSVRDKC-ALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKK 428
S+ C+C G+ +A + C ++C A CQH C + SY C C G+ L D K
Sbjct: 881 SYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC-ENTLGSYRCSCASGFLLAADGK 939
Query: 429 TCSATEEARRLVSTEDACGCEATLAFQDKVSSY 461
C ED CEA Q+ + Y
Sbjct: 940 RC------------EDVNECEAQRCSQECANIY 960
Score = 81.6 bits (200), Expect = 1e-15
Identities = 51/159 (32%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
Query: 285 GKHHCE-----CSQGYTLNADKKTCSALDRCALNTHGCEH--ICVNDRSGSYHCECYEGY 337
G + C+ C++GY + D C ++ C H C +C N GSY C+C G+
Sbjct: 832 GSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN-LPGSYRCDCKAGF 890
Query: 338 TLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCAL 396
+ + C ++C A CQH C N GS+ C C G+ L AD K C ++C
Sbjct: 891 QRDAFGRGCIDVNECWASPGRLCQHTCENT-LGSYRCSCASGFLLAADGKRCEDVNECE- 948
Query: 397 GSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
+ C C + SY C C GY L ED TC+ +E
Sbjct: 949 -AQRCSQECANI-YGSYQCYCRQGYQLAEDGHTCTDIDE 985
Score = 79.3 bits (194), Expect = 7e-15
Identities = 59/181 (32%), Positives = 84/181 (46%), Gaps = 28/181 (15%)
Query: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC---EHICVNDRSGSYHC 331
C+ VC + G G C C GY + AD +C ++ C + H C EH CVN GS+HC
Sbjct: 689 CKQVCSTVG-GSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEH-CVN-TLGSFHC 745
Query: 332 ----ECYEGYTLNEDRKTCSAQDKCALGTHGCQ--HICVNDRTGSHHCE----CYEGYTL 381
C GY L + C D+CA+GTH CQ +C N + GS +C+ C +G+ L
Sbjct: 746 YKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTK-GSFYCQARQRCMDGF-L 801
Query: 382 NADKKTCSVRDKCALGSHGCQ--HICVSDGAASYHCD-----CYPGYTLNEDKKTCSATE 434
+ C ++C S C+ C++ SY C C GY ++D C
Sbjct: 802 QDPEGNCVDINECTSLSEPCRPGFSCINT-VGSYTCQRNPLICARGYHASDDGTKCVDVN 860
Query: 435 E 435
E
Sbjct: 861 E 861
Score = 74.7 bits (182), Expect = 2e-13
Identities = 62/219 (28%), Positives = 90/219 (41%), Gaps = 52/219 (23%)
Query: 266 DPCVLGTHQ-CQHVCISDGEGKHHCECSQGYTLNADKKTC------------------SA 306
D C+L + CQH+CI+ G +HC C G++L D +TC S
Sbjct: 606 DECLLLPGELCQHLCINT-VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSE 664
Query: 307 LDRCALNT--------------HGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKC 352
+ A NT C+ +C + GS C C+ GY + D +C ++C
Sbjct: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDINEC 723
Query: 353 ALGTHGCQ--HICVNDRTGSHHC----ECYEGYTLNADKKTCSVRDKCALGSHGCQ--HI 404
H C CVN GS HC C GY L + C D+CA+G+H CQ +
Sbjct: 724 VTDLHTCSRGEHCVN-TLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFL 780
Query: 405 CVSDGAASYHCD----CYPGYTLNEDKKTCSATEEARRL 439
C + S++C C G+ L + + C E L
Sbjct: 781 C-QNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSL 817
Score = 65.9 bits (159), Expect = 8e-11
Identities = 53/197 (26%), Positives = 80/197 (40%), Gaps = 49/197 (24%)
Query: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTC---------SAQDKCALGTH---------- 357
C+H+C+N GSYHC C+ G++L +D +TC A + AL +
Sbjct: 616 CQHLCINT-VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP 674
Query: 358 -------------GCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQ-- 402
C+ +C + GS C C+ GY + AD +C ++C H C
Sbjct: 675 LPLPQPNTCKDNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRG 733
Query: 403 HICVSDGAASYHC----DCYPGYTLNEDKKTCSATEEARRLVSTEDACGCEATLAFQD-K 457
CV+ S+HC C PGY L + + C +E T C+ Q+ K
Sbjct: 734 EHCVNT-LGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHT-----CQPGFLCQNTK 785
Query: 458 VSSYLQRLNTKLDDILE 474
S Y Q +D L+
Sbjct: 786 GSFYCQARQRCMDGFLQ 802
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 35/120 (29%)
Query: 349 QDKCAL-GTHGCQHICVNDRTGSHHCECYEGYTLNADKKTC---------SVRDKCALGS 398
QD+C L CQH+C+N GS+HC C+ G++L D +TC + AL S
Sbjct: 605 QDECLLLPGELCQHLCINT-VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 399 H-----------------------GCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
C+ +C + G ++ C C+PGY + D +C E
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAI-CSCFPGYAIMADGVSCEDINE 722
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 100 bits (249), Expect = 3e-21
Identities = 61/165 (36%), Positives = 82/165 (49%), Gaps = 12/165 (7%)
Query: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECY 334
CQH C + G + C C+ G+ L AD K C ++ C C C N GSY C C
Sbjct: 960 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQECANIY-GSYQCYCR 1015
Query: 335 EGYTLNEDRKTCSAQDKCALGTH-GCQHICVNDRTGSHHCECYE-GYTLNADKKTCSVRD 392
+GY L ED TC+ D+CA G C C+N GS+ C C E GYT+ A+ ++C D
Sbjct: 1016 QGYQLAEDGHTCTDIDECAQGAGILCTFRCLN-VPGSYQCACPEQGYTMTANGRSCKDVD 1074
Query: 393 KCALGSHGCQHI-CVSDGAASYHC---DCYPGYTLNEDKKTCSAT 433
+CALG+H C + S+ C +C P Y + K C T
Sbjct: 1075 ECALGTHNCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKCERT 1118
Score = 88.2 bits (217), Expect = 2e-17
Identities = 75/256 (29%), Positives = 107/256 (41%), Gaps = 59/256 (23%)
Query: 266 DPCVLGTHQ-CQHVCISDGEGKHHCECSQGYTLNADKKTC------------------SA 306
D C+L + CQH+CI+ G +HC C G++L D +TC S
Sbjct: 606 DECLLLPGELCQHLCINT-VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSE 664
Query: 307 LDRCALNT--------------HGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKC 352
+ A NT C+ +C + GS C C+ GY + D +C QD+C
Sbjct: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDQDEC 723
Query: 353 ALGTHGC--QHICVNDRTGSHHCE-----CYEGYTLNADKKTCSVRDKCALGSHGCQ--H 403
+G H C + CVN GS +C C +GY LNA +K C ++C H C
Sbjct: 724 LMGAHDCSRRQFCVN-TLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGE 781
Query: 404 ICVSDGAASYHC----DCYPGYTLNEDKKTCSATEEARRLVSTEDACGCEATLAFQD-KV 458
CV+ S+HC C PGY L + + C +E T C+ Q+ K
Sbjct: 782 HCVNT-LGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHT-----CQPGFLCQNTKG 833
Query: 459 SSYLQRLNTKLDDILE 474
S Y Q +D L+
Sbjct: 834 SFYCQARQRCMDGFLQ 849
Score = 82.8 bits (203), Expect = 6e-16
Identities = 62/213 (29%), Positives = 92/213 (43%), Gaps = 33/213 (15%)
Query: 265 LDPCVLGTHQCQ--HVCISDGEGKHHCE----CSQGYTLNADKKTCSALDRCALNTHGCE 318
+D C +GTH CQ +C + +G +C+ C G+ L + C ++ C + C
Sbjct: 812 VDECAMGTHTCQPGFLC-QNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCR 869
Query: 319 --HICVNDRSGSYHCE-----CYEGYTLNEDRKTCSAQDKCALGTHGC--QHICVNDRTG 369
C+N GSY C+ C GY ++D C ++C G H C +C N G
Sbjct: 870 PGFSCIN-TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN-LPG 927
Query: 370 SHHCECYEGYTLNADKKTCSVRDKC-ALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKK 428
S+ C+C G+ +A + C ++C A CQH C + SY C C G+ L D K
Sbjct: 928 SYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC-ENTLGSYRCSCASGFLLAADGK 986
Query: 429 TCSATEEARRLVSTEDACGCEATLAFQDKVSSY 461
C ED CEA Q+ + Y
Sbjct: 987 RC------------EDVNECEAQRCSQECANIY 1007
Score = 81.6 bits (200), Expect = 1e-15
Identities = 51/159 (32%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
Query: 285 GKHHCE-----CSQGYTLNADKKTCSALDRCALNTHGCEH--ICVNDRSGSYHCECYEGY 337
G + C+ C++GY + D C ++ C H C +C N GSY C+C G+
Sbjct: 879 GSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN-LPGSYRCDCKAGF 937
Query: 338 TLNEDRKTCSAQDKC-ALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCAL 396
+ + C ++C A CQH C N GS+ C C G+ L AD K C ++C
Sbjct: 938 QRDAFGRGCIDVNECWASPGRLCQHTCENT-LGSYRCSCASGFLLAADGKRCEDVNECE- 995
Query: 397 GSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
+ C C + SY C C GY L ED TC+ +E
Sbjct: 996 -AQRCSQECANI-YGSYQCYCRQGYQLAEDGHTCTDIDE 1032
Score = 81.3 bits (199), Expect = 2e-15
Identities = 61/184 (33%), Positives = 82/184 (44%), Gaps = 27/184 (14%)
Query: 275 CQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGC--EHICVNDRSGSYHCE 332
C+ VC + G G C C GY + AD +C D C + H C CVN GS++C
Sbjct: 689 CKQVCSTVG-GSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVN-TLGSFYCV 746
Query: 333 -----CYEGYTLNEDRKTCSAQDKCALGTHGCQ--HICVNDRTGSHHC----ECYEGYTL 381
C +GY LN RK C ++C H C CVN GS HC C GY L
Sbjct: 747 NHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHCVN-TLGSFHCYKALTCEPGYAL 804
Query: 382 NADKKTCSVRDKCALGSHGCQ--HICVSDGAASYHCD----CYPGYTLNEDKKTCSATEE 435
+ C D+CA+G+H CQ +C + S++C C G+ L + + C E
Sbjct: 805 KDGE--CEDVDECAMGTHTCQPGFLC-QNTKGSFYCQARQRCMDGF-LQDPEGNCVDINE 860
Query: 436 ARRL 439
L
Sbjct: 861 CTSL 864
Score = 52.0 bits (123), Expect = 1e-06
Identities = 33/120 (27%), Positives = 51/120 (42%), Gaps = 35/120 (29%)
Query: 349 QDKCAL-GTHGCQHICVNDRTGSHHCECYEGYTLNADKKTC---------SVRDKCALGS 398
QD+C L CQH+C+N GS+HC C+ G++L D +TC + AL S
Sbjct: 605 QDECLLLPGELCQHLCINT-VGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 399 H-----------------------GCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435
C+ +C + G ++ C C+PGY + D +C +E
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAI-CSCFPGYAIMADGVSCEDQDE 722
>gi|21359974 vitrin [Homo sapiens]
Length = 693
Score = 99.8 bits (247), Expect = 5e-21
Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 6/181 (3%)
Query: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
D+ F+ID S SV F V FV+ + +I DTR+ V Y ++EF Y+
Sbjct: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
Query: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
K + A+ R+ S GT +G AI A+++ F ++ N K+ I++TDGR D
Sbjct: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLF------KKSKPNKRKLMILITDGRSYDD 623
Query: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQETF 262
V A A G+ YA+GV A L+++A+ P +H F+V+ + + + R +
Sbjct: 624 VRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
Query: 263 C 263
C
Sbjct: 684 C 684
Score = 79.3 bits (194), Expect = 7e-15
Identities = 64/230 (27%), Positives = 100/230 (43%), Gaps = 31/230 (13%)
Query: 17 LWPLLLLPSAAPDPVARPGFRRLETRGPGGSPGRRPSPA--------------------- 55
LW S+ P A PG +R + P G+ ++P A
Sbjct: 228 LWSTATYTSSQNRPRADPGIQRQD---PSGAAFQKPVGADVSLGEMDSWKPGSVLLDEGL 284
Query: 56 APDGAPASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDI 115
P ++ + EP + G CK +DL F+ID S S+ F K ++ + LDI
Sbjct: 285 VPKEELSTQSLEPV-SLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDI 340
Query: 116 GPADTRVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFT 175
GPA + VV Y F L+ +T+ + LK A+ +IT + G AI F+
Sbjct: 341 GPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFS 400
Query: 176 VEAGAREPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRA 225
G R S P V +++ DG P D+V E + A+ SGI ++ + ++ A
Sbjct: 401 KANGNR---SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGA 447
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 98.6 bits (244), Expect = 1e-20
Identities = 57/183 (31%), Positives = 96/183 (52%), Gaps = 3/183 (1%)
Query: 81 PLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAY 140
P D+VF++D S S+ F +VK F++ +I +IGP +V + Y+ + E+ L +
Sbjct: 177 PADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSL 236
Query: 141 TDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQ 200
+ K+ + AV R+ T +GLA+ + + AG R ++ KV I+VTDG+ Q
Sbjct: 237 STKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAA---KVVILVTDGKSQ 293
Query: 201 DQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQE 260
D V+ A + G+ ++AVGV AD A L+++AS P + V V + + L+
Sbjct: 294 DDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSR 353
Query: 261 TFC 263
C
Sbjct: 354 LIC 356
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 98.2 bits (243), Expect = 1e-20
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 5/179 (2%)
Query: 273 HQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHC 331
H C H + EG C C QGY + C ++ C + C+ C+N +GSY C
Sbjct: 1129 HLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT-AGSYDC 1187
Query: 332 ECYEGYTLNEDRKTCSAQDKCAL-GTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSV 390
C +G+ L +D KTC ++C G G Q C+N GS HC C +G++++AD +TC
Sbjct: 1188 TCPDGFQL-DDNKTCQDINECEHPGLCGPQGECLNTE-GSFHCVCQQGFSISADGRTCED 1245
Query: 391 RDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACGCE 449
D+C + H + A S+ C CY G+ +D + C E L CE
Sbjct: 1246 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCE 1304
Score = 81.3 bits (199), Expect = 2e-15
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 8/180 (4%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCAL-NTHGCEHICVN 323
++ C+ CQ + G + C C G+ L+ D KTC ++ C G + C+N
Sbjct: 1163 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLN 1221
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNA 383
GS+HC C +G++++ D +TC D+C T H ++ GS C CY+G+
Sbjct: 1222 TE-GSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 1280
Query: 384 DKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTE 443
D + C ++C L S C + S+ C C +E+++ T + R ST+
Sbjct: 1281 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC-----ADENQEYSPMTGQCRSRTSTD 1335
Score = 75.9 bits (185), Expect = 8e-14
Identities = 60/220 (27%), Positives = 89/220 (40%), Gaps = 32/220 (14%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHC-ECSQGYTLNADKKTCSALDRCALNTHGCEHICVN 323
+D C L C + G + C C++G+ C +D C L + C + +
Sbjct: 1000 IDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLDVDEC-LEPNVCANGDCS 1055
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN----DRTGSHHCECYEGY 379
+ GSY C C++GYT D K C D+C G ++CVN + GS C C +GY
Sbjct: 1056 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-----NLCVNGQCKNTEGSFRCTCGQGY 1110
Query: 380 TLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLN-------------ED 426
L+A K C D+C H C H + S+ C C GY + ED
Sbjct: 1111 QLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLED 1169
Query: 427 KKTCSATEEARRLVSTEDACGCEATLAFQDKVSSYLQRLN 466
K C + ++T + C FQ + Q +N
Sbjct: 1170 KSVCQRGD----CINTAGSYDCTCPDGFQLDDNKTCQDIN 1205
Score = 66.6 bits (161), Expect = 5e-11
Identities = 50/216 (23%), Positives = 83/216 (38%), Gaps = 47/216 (21%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
C ++P + G C ++ + ++ C C +GY + ++ C +D C H C
Sbjct: 878 CTVNPDICGAGHCINLPV-----RYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 932
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCE-CYEGYTL 381
+ GS+ C C G+ +E+ C D+C + CVN G+ CE C GY +
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVN-TVGAFRCEYCDSGYRM 991
Query: 382 NADKKTCSVRDKC-------------ALGSHGC----------------------QHICV 406
+ C D+C + GS+ C ++C
Sbjct: 992 -TQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCA 1050
Query: 407 ----SDGAASYHCDCYPGYTLNEDKKTCSATEEARR 438
S+ SY C C+ GYT D K C +E ++
Sbjct: 1051 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ 1086
Score = 50.4 bits (119), Expect = 4e-06
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 307 LDRCALNTHGC-EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN 365
++ C +N C C+N Y C CYEGY +E ++ C D+C H C
Sbjct: 875 INECTVNPDICGAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 366 DRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCD-CYPGYTLN 424
+ GS C C G+ + + C D+C + CV+ ++ C+ C GY +
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNT-VGAFRCEYCDSGYRMT 992
Query: 425 E 425
+
Sbjct: 993 Q 993
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 373 CECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSA 432
C CYEGY + ++ C D+C H C + S+ C C G+ +E+ C
Sbjct: 899 CICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCID 958
Query: 433 TEEARRLVSTEDACG 447
+E R D CG
Sbjct: 959 VDECLR----PDVCG 969
Score = 43.9 bits (102), Expect = 3e-04
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
Query: 350 DKCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHG---CQHIC 405
++C + +GC++ CV + G + C+C++GY L+ K TC ++C ++ C++
Sbjct: 1624 EECGI-LNGCENGRCVRVQEG-YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAK 1681
Query: 406 VSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTED 444
+ SY C C PGY ++ C+ A L D
Sbjct: 1682 CINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSD 1720
Score = 41.6 bits (96), Expect = 0.002
Identities = 40/160 (25%), Positives = 57/160 (35%), Gaps = 21/160 (13%)
Query: 252 EKLSSRFQETFCALDPCVL-GTHQCQH-VCISDGEGKHHCECSQGYTLNADKKTCSALDR 309
E S E + D C+L G C++ C++ G + C C QG + K C +D
Sbjct: 1413 ESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPG-YECYCKQGTYYDPVKLQCFDMDE 1471
Query: 310 CALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSA--------------QDKC--- 352
C + + CVN GSY+C C L+ K C QD C
Sbjct: 1472 CQDPSSCIDGQCVN-TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1530
Query: 353 ALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRD 392
+ C V +T C C G C ++D
Sbjct: 1531 LSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD 1570
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Query: 315 HGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN----DRTG 369
+GCE+ CV + G Y C+C++GY L+ + TC ++C + +C N + G
Sbjct: 1630 NGCENGRCVRVQEG-YTCDCFDGYHLDTAKMTCVDVNECD-ELNNRMSLCKNAKCINTDG 1687
Query: 370 SHHCECYEGYTLNADKKTCS 389
S+ C C GY + C+
Sbjct: 1688 SYKCLCLPGYVPSDKPNYCT 1707
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 279 CISDGEGKHHCECSQGYTLNADKKTCSALDRC-ALNTHG--CEHICVNDRSGSYHCECYE 335
C+ EG + C+C GY L+ K TC ++ C LN C++ + GSY C C
Sbjct: 1637 CVRVQEG-YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1695
Query: 336 GYTLNEDRKTCS 347
GY ++ C+
Sbjct: 1696 GYVPSDKPNYCT 1707
Score = 38.5 bits (88), Expect = 0.014
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 350 DKCAL-GTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
D+C L G C++ C+N R G + C C +G + K C D+C S CV+
Sbjct: 1427 DECLLFGQEICKNGFCLNTRPG-YECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN 1485
Query: 408 DGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTED 444
SY+C C L+ +K C E+ + D
Sbjct: 1486 T-EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETD 1521
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 98.2 bits (243), Expect = 1e-20
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 5/179 (2%)
Query: 273 HQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEH-ICVNDRSGSYHC 331
H C H + EG C C QGY + C ++ C + C+ C+N +GSY C
Sbjct: 803 HLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINT-AGSYDC 861
Query: 332 ECYEGYTLNEDRKTCSAQDKCAL-GTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSV 390
C +G+ L +D KTC ++C G G Q C+N GS HC C +G++++AD +TC
Sbjct: 862 TCPDGFQL-DDNKTCQDINECEHPGLCGPQGECLNTE-GSFHCVCQQGFSISADGRTCED 919
Query: 391 RDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACGCE 449
D+C + H + A S+ C CY G+ +D + C E L CE
Sbjct: 920 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCE 978
Score = 81.3 bits (199), Expect = 2e-15
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 8/180 (4%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCAL-NTHGCEHICVN 323
++ C+ CQ + G + C C G+ L+ D KTC ++ C G + C+N
Sbjct: 837 INECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLN 895
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNA 383
GS+HC C +G++++ D +TC D+C T H ++ GS C CY+G+
Sbjct: 896 TE-GSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ 954
Query: 384 DKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTE 443
D + C ++C L S C + S+ C C +E+++ T + R ST+
Sbjct: 955 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC-----ADENQEYSPMTGQCRSRTSTD 1009
Score = 75.9 bits (185), Expect = 8e-14
Identities = 60/220 (27%), Positives = 89/220 (40%), Gaps = 32/220 (14%)
Query: 265 LDPCVLGTHQCQHVCISDGEGKHHC-ECSQGYTLNADKKTCSALDRCALNTHGCEHICVN 323
+D C L C + G + C C++G+ C +D C L + C + +
Sbjct: 674 IDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF--RGWNGQCLDVDEC-LEPNVCANGDCS 729
Query: 324 DRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN----DRTGSHHCECYEGY 379
+ GSY C C++GYT D K C D+C G ++CVN + GS C C +GY
Sbjct: 730 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-----NLCVNGQCKNTEGSFRCTCGQGY 784
Query: 380 TLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLN-------------ED 426
L+A K C D+C H C H + S+ C C GY + ED
Sbjct: 785 QLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLED 843
Query: 427 KKTCSATEEARRLVSTEDACGCEATLAFQDKVSSYLQRLN 466
K C + ++T + C FQ + Q +N
Sbjct: 844 KSVCQRGD----CINTAGSYDCTCPDGFQLDDNKTCQDIN 879
Score = 66.6 bits (161), Expect = 5e-11
Identities = 50/216 (23%), Positives = 83/216 (38%), Gaps = 47/216 (21%)
Query: 263 CALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICV 322
C ++P + G C ++ + ++ C C +GY + ++ C +D C H C
Sbjct: 552 CTVNPDICGAGHCINLPV-----RYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
Query: 323 NDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCE-CYEGYTL 381
+ GS+ C C G+ +E+ C D+C + CVN G+ CE C GY +
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVN-TVGAFRCEYCDSGYRM 665
Query: 382 NADKKTCSVRDKC-------------ALGSHGC----------------------QHICV 406
+ C D+C + GS+ C ++C
Sbjct: 666 -TQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCA 724
Query: 407 ----SDGAASYHCDCYPGYTLNEDKKTCSATEEARR 438
S+ SY C C+ GYT D K C +E ++
Sbjct: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQ 760
Score = 50.4 bits (119), Expect = 4e-06
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 307 LDRCALNTHGC-EHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN 365
++ C +N C C+N Y C CYEGY +E ++ C D+C H C
Sbjct: 549 INECTVNPDICGAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 366 DRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCD-CYPGYTLN 424
+ GS C C G+ + + C D+C + CV+ ++ C+ C GY +
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNT-VGAFRCEYCDSGYRMT 666
Query: 425 E 425
+
Sbjct: 667 Q 667
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 373 CECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSA 432
C CYEGY + ++ C D+C H C + S+ C C G+ +E+ C
Sbjct: 573 CICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCID 632
Query: 433 TEEARRLVSTEDACG 447
+E R D CG
Sbjct: 633 VDECLR----PDVCG 643
Score = 43.9 bits (102), Expect = 3e-04
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
Query: 350 DKCALGTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHG---CQHIC 405
++C + +GC++ CV + G + C+C++GY L+ K TC ++C ++ C++
Sbjct: 1298 EECGI-LNGCENGRCVRVQEG-YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAK 1355
Query: 406 VSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTED 444
+ SY C C PGY ++ C+ A L D
Sbjct: 1356 CINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSD 1394
Score = 41.6 bits (96), Expect = 0.002
Identities = 40/160 (25%), Positives = 57/160 (35%), Gaps = 21/160 (13%)
Query: 252 EKLSSRFQETFCALDPCVL-GTHQCQH-VCISDGEGKHHCECSQGYTLNADKKTCSALDR 309
E S E + D C+L G C++ C++ G + C C QG + K C +D
Sbjct: 1087 ESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPG-YECYCKQGTYYDPVKLQCFDMDE 1145
Query: 310 CALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSA--------------QDKC--- 352
C + + CVN GSY+C C L+ K C QD C
Sbjct: 1146 CQDPSSCIDGQCVN-TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEH 1204
Query: 353 ALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRD 392
+ C V +T C C G C ++D
Sbjct: 1205 LSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD 1244
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Query: 315 HGCEH-ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVN----DRTG 369
+GCE+ CV + G Y C+C++GY L+ + TC ++C + +C N + G
Sbjct: 1304 NGCENGRCVRVQEG-YTCDCFDGYHLDTAKMTCVDVNECD-ELNNRMSLCKNAKCINTDG 1361
Query: 370 SHHCECYEGYTLNADKKTCS 389
S+ C C GY + C+
Sbjct: 1362 SYKCLCLPGYVPSDKPNYCT 1381
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 279 CISDGEGKHHCECSQGYTLNADKKTCSALDRC-ALNTHG--CEHICVNDRSGSYHCECYE 335
C+ EG + C+C GY L+ K TC ++ C LN C++ + GSY C C
Sbjct: 1311 CVRVQEG-YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1369
Query: 336 GYTLNEDRKTCS 347
GY ++ C+
Sbjct: 1370 GYVPSDKPNYCT 1381
Score = 38.5 bits (88), Expect = 0.014
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 350 DKCAL-GTHGCQH-ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
D+C L G C++ C+N R G + C C +G + K C D+C S CV+
Sbjct: 1101 DECLLFGQEICKNGFCLNTRPG-YECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVN 1159
Query: 408 DGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTED 444
SY+C C L+ +K C E+ + D
Sbjct: 1160 T-EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETD 1195
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,212,572
Number of Sequences: 37866
Number of extensions: 1093113
Number of successful extensions: 9850
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 324
Number of HSP's that attempted gapping in prelim test: 6450
Number of HSP's gapped (non-prelim): 1952
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.