Guide to the Human Genome
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Search of human proteins with 10140847

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10140847 homeobox A2 [Homo sapiens]
         (376 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10140847 homeobox A2 [Homo sapiens]                                761   0.0  
gi|4504465 homeobox B2 [Homo sapiens]                                 304   1e-82
gi|19923391 homeobox D3 [Homo sapiens]                                130   2e-30
gi|24497513 homeobox A3 isoform a [Homo sapiens]                      122   5e-28
gi|13562112 homeobox A3 isoform a [Homo sapiens]                      122   5e-28
gi|84570137 homeobox B3 [Homo sapiens]                                115   6e-26
gi|24497515 homeobox A3 isoform b [Homo sapiens]                      105   5e-23
gi|18959212 GS homeobox 2 [Homo sapiens]                              100   2e-21
gi|24497517 homeobox A5 [Homo sapiens]                                100   3e-21
gi|23397672 homeobox D4 [Homo sapiens]                                 99   8e-21
gi|33457326 GS homeobox 1 [Homo sapiens]                               99   8e-21
gi|13273315 homeobox B4 [Homo sapiens]                                 97   2e-20
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           97   3e-20
gi|148613882 homeobox A4 [Homo sapiens]                                97   3e-20
gi|24497538 homeobox C4 [Homo sapiens]                                 96   4e-20
gi|24497540 homeobox C4 [Homo sapiens]                                 96   4e-20
gi|4504469 homeobox B5 [Homo sapiens]                                  96   7e-20
gi|11321638 homeobox C5 [Homo sapiens]                                 93   4e-19
gi|24497544 homeobox C6 isoform 2 [Homo sapiens]                       93   4e-19
gi|4758554 homeobox C6 isoform 1 [Homo sapiens]                        93   4e-19
gi|24497526 homeobox B1 [Homo sapiens]                                 92   8e-19
gi|85068580 homeobox B7 [Homo sapiens]                                 91   1e-18
gi|13489077 homeobox A6 [Homo sapiens]                                 90   3e-18
gi|13375632 homeobox D1 [Homo sapiens]                                 90   4e-18
gi|5031761 homeobox A1 isoform a [Homo sapiens]                        90   4e-18
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     90   4e-18
gi|24497556 homeobox A7 [Homo sapiens]                                 89   6e-18
gi|23503237 homeobox B6 [Homo sapiens]                                 89   6e-18
gi|12056969 homeobox C8 [Homo sapiens]                                 88   1e-17
gi|89257348 homeo box HB9 [Homo sapiens]                               87   2e-17

>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score =  761 bits (1965), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLN 60
           MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLN
Sbjct: 1   MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLN 60

Query: 61  PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA 120
           PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA
Sbjct: 61  PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA 120

Query: 121 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 180
           ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL
Sbjct: 121 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 180

Query: 181 DLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVS 240
           DLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVS
Sbjct: 181 DLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVS 240

Query: 241 GALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLST 300
           GALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLST
Sbjct: 241 GALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLST 300

Query: 301 MGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSLD 360
           MGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSLD
Sbjct: 301 MGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSLD 360

Query: 361 FFTDTLTTIDLQHLNY 376
           FFTDTLTTIDLQHLNY
Sbjct: 361 FFTDTLTTIDLQHLNY 376


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score =  304 bits (778), Expect = 1e-82
 Identities = 191/383 (49%), Positives = 222/383 (57%), Gaps = 40/383 (10%)

Query: 1   MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLN 60
           MN+EFEREIGFINSQPSLAECLTSFP V +TFQ+SSIK STL      PPPFEQT PSL 
Sbjct: 1   MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPP---PPPFEQTFPSLQ 57

Query: 61  PGSHP--RHGAGGRPKPSPAGSRGSPVPAGALQP-PEYPWMKEKKAAKKTALLPAAAAAA 117
           PG+    R  +  R +  PA     P P  A  P PE+PWMKEKK+AKK +    + + A
Sbjct: 58  PGASTLQRPRSQKRAEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPA 117

Query: 118 TAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA 177
            +A       S  + L + +  GGG+RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA
Sbjct: 118 ASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA 177

Query: 178 ALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCK-SLEDSEKVEEDEEEKTLFEQA 236
           ALLDLTERQVKVWFQNRRMKHKRQTQ +E  + E  C  +LED     E        E A
Sbjct: 178 ALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAE--------EPA 229

Query: 237 LSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPN 296
            S  G    R  +  +      +  P   + D +   V             +    + P 
Sbjct: 230 ASPGGPSASRAAW--EACCHPPEVVPGALSADPRPLAV-----------RLEGAGASSPG 276

Query: 297 CLSTMGQNCGAGLNNDSPEALEV-------PSLQDFSVFSTDSCLQLSDAVSPSLPGSLD 349
           C        GAG     P   +V       P L D + F+ DSCLQLS  +SPSL GSLD
Sbjct: 277 CALR-----GAGGLEPGPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSLQGSLD 331

Query: 350 SPVDISADSLDFFTDTLTTIDLQ 372
           SPV  S + LDFFT TL  IDLQ
Sbjct: 332 SPVPFSEEELDFFTSTLCAIDLQ 354


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score =  130 bits (327), Expect = 2e-30
 Identities = 69/157 (43%), Positives = 90/157 (57%), Gaps = 19/157 (12%)

Query: 49  PPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTA 108
           PPP   T+P     S P +  GG P   P G   +   +  +    +PWMKE +   K  
Sbjct: 119 PPPPPPTLPP----SSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQK 174

Query: 109 LLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYL 168
                           +C +  ES E     G  S+R+RTAYT+ QL+ELEKEFHFN+YL
Sbjct: 175 ---------------NSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYL 219

Query: 169 CRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCK 205
           CRPRRVE+A LL+LTERQ+K+WFQNRRMK+K+  + K
Sbjct: 220 CRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAK 256


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score =  122 bits (306), Expect = 5e-28
 Identities = 75/200 (37%), Positives = 103/200 (51%), Gaps = 31/200 (15%)

Query: 31  TFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSH----PRHGAGGRPKPS----PAGSRG 82
           T  +   +  +L    L PPP +   P+  P       P       P PS    P  +  
Sbjct: 74  TLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASN 133

Query: 83  SPVPAGALQPPE----------YPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKES 132
           +P PA A + P           +PWMKE +   K           +++++G +C   K  
Sbjct: 134 NPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQK--------TSSSSSGESCAGDK-- 183

Query: 133 LEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQ 192
              +      S+R RTAYT+ QL+ELEKEFHFN+YLCRPRRVE+A LL+LTERQ+K+WFQ
Sbjct: 184 ---SPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 240

Query: 193 NRRMKHKRQTQCKENQNSEG 212
           NRRMK+K+  + K    S G
Sbjct: 241 NRRMKYKKDQKGKGMLTSSG 260


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score =  122 bits (306), Expect = 5e-28
 Identities = 75/200 (37%), Positives = 103/200 (51%), Gaps = 31/200 (15%)

Query: 31  TFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSH----PRHGAGGRPKPS----PAGSRG 82
           T  +   +  +L    L PPP +   P+  P       P       P PS    P  +  
Sbjct: 74  TLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASN 133

Query: 83  SPVPAGALQPPE----------YPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKES 132
           +P PA A + P           +PWMKE +   K           +++++G +C   K  
Sbjct: 134 NPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQK--------TSSSSSGESCAGDK-- 183

Query: 133 LEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQ 192
              +      S+R RTAYT+ QL+ELEKEFHFN+YLCRPRRVE+A LL+LTERQ+K+WFQ
Sbjct: 184 ---SPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 240

Query: 193 NRRMKHKRQTQCKENQNSEG 212
           NRRMK+K+  + K    S G
Sbjct: 241 NRRMKYKKDQKGKGMLTSSG 260


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score =  115 bits (288), Expect = 6e-26
 Identities = 66/166 (39%), Positives = 84/166 (50%), Gaps = 10/166 (6%)

Query: 57  PSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAA 116
           PS  P S   + + G         +  P     L    +PWMKE +   K        A 
Sbjct: 92  PSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAE 151

Query: 117 ATAAATGPACLSHKESLEIADGSGGG----------SRRLRTAYTNTQLLELEKEFHFNK 166
                 G              G GGG          S+R RTAYT+ QL+ELEKEFHFN+
Sbjct: 152 GCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNR 211

Query: 167 YLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEG 212
           YLCRPRRVE+A LL+L+ERQ+K+WFQNRRMK+K+  + K   +S G
Sbjct: 212 YLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSG 257


>gi|24497515 homeobox A3 isoform b [Homo sapiens]
          Length = 285

 Score =  105 bits (263), Expect = 5e-23
 Identities = 51/95 (53%), Positives = 69/95 (72%), Gaps = 5/95 (5%)

Query: 118 TAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA 177
           +++++G +C   K     +      S+R RTAYT+ QL+ELEKEFHFN+YLCRPRRVE+A
Sbjct: 13  SSSSSGESCAGDK-----SPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMA 67

Query: 178 ALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEG 212
            LL+LTERQ+K+WFQNRRMK+K+  + K    S G
Sbjct: 68  NLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSG 102


>gi|18959212 GS homeobox 2 [Homo sapiens]
          Length = 304

 Score =  100 bits (249), Expect = 2e-21
 Identities = 62/144 (43%), Positives = 85/144 (59%), Gaps = 24/144 (16%)

Query: 112 AAAAAATAAATGPACLSHKE---------SLEIADG------SGGGS--------RRLRT 148
           AAAAAA AAA   A L H +         +  +AD       + GGS        +R+RT
Sbjct: 148 AAAAAAAAAAAAAAALGHPQHHAPVCTATTYNVADPRRFHCLTMGGSDASQVPNGKRMRT 207

Query: 149 AYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQ 208
           A+T+TQLLELE+EF  N YL R RR+EIA  L+L+E+QVK+WFQNRR+KHK++ +  + +
Sbjct: 208 AFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQ-R 266

Query: 209 NSEGKCKSLEDSEKVEEDEEEKTL 232
           NS   CK +         E+E +L
Sbjct: 267 NSHAGCKCVGSQVHYARSEDEDSL 290


>gi|24497517 homeobox A5 [Homo sapiens]
          Length = 270

 Score =  100 bits (248), Expect = 3e-21
 Identities = 68/175 (38%), Positives = 93/175 (53%), Gaps = 16/175 (9%)

Query: 40  STLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMK 99
           +T +HS   P P   +  + +PGS   HG     K S + S G+   AG+        + 
Sbjct: 90  ATSTHSPQ-PDPLPCSAVAPSPGSDSHHGG----KNSLSNSSGASADAGSTHISSREGVG 144

Query: 100 EKKAAKKTALLPAAAAAATAAA-------TGPACLSHKESLEIADGSGGG--SRRLRTAY 150
               A++ A  PA++  A+A +         P        L I+  + GG   +R RTAY
Sbjct: 145 TASGAEEDA--PASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAY 202

Query: 151 TNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCK 205
           T  Q LELEKEFHFN+YL R RR+EIA  L L+ERQ+K+WFQNRRMK K+  + K
Sbjct: 203 TRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLK 257


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score = 98.6 bits (244), Expect = 8e-21
 Identities = 64/160 (40%), Positives = 84/160 (52%), Gaps = 16/160 (10%)

Query: 61  PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA 120
           PG H  + A G P P+P     +P+P         P    K+    TAL   A       
Sbjct: 85  PGGH--YAAPGEPCPAPPAPPPAPLPGARAYSQSDP----KQPPSGTALKQPAVVYPWMK 138

Query: 121 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 180
                   H  S+   + +GG  +R RTAYT  Q+LELEKEFHFN+YL R RR+EIA  L
Sbjct: 139 KV------HVNSVN-PNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTL 191

Query: 181 DLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDS 220
            L+ERQ+K+WFQNRRMK K+  +     N++G+  S   S
Sbjct: 192 CLSERQIKIWFQNRRMKWKKDHKL---PNTKGRSSSSSSS 228


>gi|33457326 GS homeobox 1 [Homo sapiens]
          Length = 264

 Score = 98.6 bits (244), Expect = 8e-21
 Identities = 68/215 (31%), Positives = 101/215 (46%), Gaps = 36/215 (16%)

Query: 48  IPPPFEQTIPSLNPGSHPRHGAG----------GRPKPSPAGSRGSPVPAGALQPPEYPW 97
           +PPP    +  L+PG+     AG                P G    P+   +  P    +
Sbjct: 33  VPPP--HALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQY 90

Query: 98  MKEKKAAKKTALLPAAAAAATAAATGPACLS-----------HKESLEIADGSGGGSRRL 146
                  + +A+ P  A    AAA   A              H  S++ +      S+R+
Sbjct: 91  CHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRM 150

Query: 147 RTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKE 206
           RTA+T+TQLLELE+EF  N YL R RR+EIA  L+L+E+QVK+WFQNRR+KHK++ +   
Sbjct: 151 RTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSN 210

Query: 207 NQNSEG-------------KCKSLEDSEKVEEDEE 228
           ++   G             KC SL  ++  E+D+E
Sbjct: 211 HRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDE 245


>gi|13273315 homeobox B4 [Homo sapiens]
          Length = 251

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 63/160 (39%), Positives = 82/160 (51%), Gaps = 23/160 (14%)

Query: 49  PPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSR----GSPVPAGALQPPEYPWMKEKKAA 104
           PPP     P   PG  PR      P P PAG+     G    A +  PP  P  +     
Sbjct: 75  PPPPPPPPPPPPPGLSPR-----APAPPPAGALLPEPGQRCEAVSSSPPPPPCAQN---- 125

Query: 105 KKTALLPAAAAAATAAATGPACLSHKESLEIA----DGSGGGSRRLRTAYTNTQLLELEK 160
                 P   + + +A   P        + ++    + +GG  +R RTAYT  Q+LELEK
Sbjct: 126 ------PLHPSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEK 179

Query: 161 EFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200
           EFH+N+YL R RRVEIA  L L+ERQ+K+WFQNRRMK K+
Sbjct: 180 EFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKK 219


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 59/138 (42%), Positives = 71/138 (51%), Gaps = 27/138 (19%)

Query: 73  PKPSPAGSRGSPVPAGALQPPE-----YPWMKEKKAAKKTALLPAAAAAATAAATGPACL 127
           P P PAG        G L+ P      +PWMK  KA          A AA          
Sbjct: 93  PHP-PAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEE------ 145

Query: 128 SHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQV 187
                          ++R RTAYT  QLLELEKEF FNKY+ RPRRVE+A +L+LTER +
Sbjct: 146 ---------------NKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHI 190

Query: 188 KVWFQNRRMKHKRQTQCK 205
           K+WFQNRRMK K++   K
Sbjct: 191 KIWFQNRRMKWKKEEDKK 208


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 64/164 (39%), Positives = 80/164 (48%), Gaps = 42/164 (25%)

Query: 48  IPPPFEQTIPSLNPGSHPRHGAGGRPKPS-PAGSRG----------SPVPAGALQPPEYP 96
           +PPP +   P   P + PR        P  PAG             SP+     +P  YP
Sbjct: 140 LPPPLQ---PRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLADKSPLGLKGKEPVVYP 196

Query: 97  WMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLL 156
           WMK+                   +A  P+             +GG  +R RTAYT  Q+L
Sbjct: 197 WMKK----------------IHVSAVNPSY------------NGGEPKRSRTAYTRQQVL 228

Query: 157 ELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200
           ELEKEFHFN+YL R RR+EIA  L L+ERQVK+WFQNRRMK K+
Sbjct: 229 ELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKK 272


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 57/140 (40%), Positives = 74/140 (52%), Gaps = 32/140 (22%)

Query: 65  PRHGAGGRPKPSPAG----SRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA 120
           P  GA   P P+P      +   P  A + QP  YPWMK+                    
Sbjct: 102 PLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKK-------------------- 141

Query: 121 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 180
                   H  ++   + +GG  +R RTAYT  Q+LELEKEFH+N+YL R RR+EIA  L
Sbjct: 142 -------IHVSTVN-PNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSL 193

Query: 181 DLTERQVKVWFQNRRMKHKR 200
            L+ERQ+K+WFQNRRMK K+
Sbjct: 194 CLSERQIKIWFQNRRMKWKK 213


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 57/140 (40%), Positives = 74/140 (52%), Gaps = 32/140 (22%)

Query: 65  PRHGAGGRPKPSPAG----SRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA 120
           P  GA   P P+P      +   P  A + QP  YPWMK+                    
Sbjct: 102 PLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKK-------------------- 141

Query: 121 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 180
                   H  ++   + +GG  +R RTAYT  Q+LELEKEFH+N+YL R RR+EIA  L
Sbjct: 142 -------IHVSTVN-PNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSL 193

Query: 181 DLTERQVKVWFQNRRMKHKR 200
            L+ERQ+K+WFQNRRMK K+
Sbjct: 194 CLSERQIKIWFQNRRMKWKK 213


>gi|4504469 homeobox B5 [Homo sapiens]
          Length = 269

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 62/160 (38%), Positives = 80/160 (50%), Gaps = 9/160 (5%)

Query: 54  QTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPV-----PAGALQPPEYPWMKEKKAAKKTA 108
           +++P  N  SH    +   P      +  S        A A   PE     +  +     
Sbjct: 98  ESLPCTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEA-ASQLSSPSLAR 156

Query: 109 LLPAAAAAATAAATG--PACLSHKESLEIA-DGSGGGSRRLRTAYTNTQLLELEKEFHFN 165
             P   A +TAA  G  P        L I+ D +G   +R RTAYT  Q LELEKEFHFN
Sbjct: 157 AQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFN 216

Query: 166 KYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCK 205
           +YL R RR+EIA  L L+ERQ+K+WFQNRRMK K+  + K
Sbjct: 217 RYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLK 256


>gi|11321638 homeobox C5 [Homo sapiens]
          Length = 222

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 69/196 (35%), Positives = 89/196 (45%), Gaps = 21/196 (10%)

Query: 29  ADTFQSSSIKTSTLSHSTLIPPPFEQTI-----PSLNPGSHP-RHGAGGRPKPSPAGSRG 82
           A   Q+S      L  S   PPP           + NP +HP R        P  A  R 
Sbjct: 30  ASEVQASRYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAPGRD 89

Query: 83  SPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKES---------- 132
              P   L P  Y     + A ++ A          A    PA LS   +          
Sbjct: 90  EAAP---LNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTK 146

Query: 133 LEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQ 192
           L ++  + G  +R RT+YT  Q LELEKEFHFN+YL R RR+EIA  L L ERQ+K+WFQ
Sbjct: 147 LHMSHETDG--KRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQ 204

Query: 193 NRRMKHKRQTQCKENQ 208
           NRRMK K+ ++ K  +
Sbjct: 205 NRRMKWKKDSKMKSKE 220


>gi|24497544 homeobox C6 isoform 2 [Homo sapiens]
          Length = 153

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 50/97 (51%), Positives = 61/97 (62%), Gaps = 4/97 (4%)

Query: 138 GSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK 197
           G G   RR R  Y+  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK
Sbjct: 54  GYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 113

Query: 198 HKRQTQCKENQNSEGKCKSLED----SEKVEEDEEEK 230
            K+++      +  G   + +      EK EE EEEK
Sbjct: 114 WKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEK 150


>gi|4758554 homeobox C6 isoform 1 [Homo sapiens]
          Length = 235

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 50/97 (51%), Positives = 61/97 (62%), Gaps = 4/97 (4%)

Query: 138 GSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK 197
           G G   RR R  Y+  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK
Sbjct: 136 GYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 195

Query: 198 HKRQTQCKENQNSEGKCKSLED----SEKVEEDEEEK 230
            K+++      +  G   + +      EK EE EEEK
Sbjct: 196 WKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEK 232


>gi|24497526 homeobox B1 [Homo sapiens]
          Length = 301

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 59/153 (38%), Positives = 76/153 (49%), Gaps = 33/153 (21%)

Query: 57  PSLNPGSHPRHGAGGRPKPSPAGS------RGSPVPAGALQPPE--YPWMKEKKAAKKTA 108
           P   P  HP +G       +PA +      + +P P+    P    + WMK K+   KTA
Sbjct: 134 PGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTA 193

Query: 109 LLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYL 168
                                    ++++   G    LRT +T  QL ELEKEFHFNKYL
Sbjct: 194 -------------------------KVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYL 228

Query: 169 CRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 201
            R RRVEIAA L+L E QVK+WFQNRRMK K++
Sbjct: 229 SRARRVEIAATLELNETQVKIWFQNRRMKQKKR 261


>gi|85068580 homeobox B7 [Homo sapiens]
          Length = 217

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 50/91 (54%), Positives = 62/91 (68%), Gaps = 6/91 (6%)

Query: 139 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 198
           SG   +R R  YT  Q LELEKEFH+N+YL R RR+EIA  L LTERQ+K+WFQNRRMK 
Sbjct: 133 SGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKW 192

Query: 199 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEE 229
           K     KEN+ + G   + +D  + EE+EEE
Sbjct: 193 K-----KENKTA-GPGTTGQDRAEAEEEEEE 217


>gi|13489077 homeobox A6 [Homo sapiens]
          Length = 233

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 63/147 (42%), Positives = 74/147 (50%), Gaps = 8/147 (5%)

Query: 76  SPAGSRGSPVPAGALQ-PPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLE 134
           SP+GS     P   L   PE  +  +  + +  AL    A     +   P          
Sbjct: 89  SPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAG 148

Query: 135 IADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNR 194
              GS G  RR R  YT  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNR
Sbjct: 149 AVYGSHG--RRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNR 206

Query: 195 RMKHKRQTQCKENQNSEGKCKSLEDSE 221
           RMK K     KEN+       S EDSE
Sbjct: 207 RMKWK-----KENKLINSTQPSGEDSE 228


>gi|13375632 homeobox D1 [Homo sapiens]
          Length = 328

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 60/155 (38%), Positives = 76/155 (49%), Gaps = 29/155 (18%)

Query: 49  PPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPP--EYPWMKEKKAAKK 106
           P PF   + +   G HP  GA     P+P     S  PA  L      + WMK K+ A K
Sbjct: 160 PGPFPACLKASADG-HP--GAFQTASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASK 216

Query: 107 TALLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNK 166
              L    AA+ ++A                        +RT ++  QL ELEKEFHFNK
Sbjct: 217 KGKLAEYGAASPSSA------------------------IRTNFSTKQLTELEKEFHFNK 252

Query: 167 YLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 201
           YL R RR+EIA  L L + QVK+WFQNRRMK K++
Sbjct: 253 YLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKR 287


>gi|5031761 homeobox A1 isoform a [Homo sapiens]
          Length = 335

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 63/176 (35%), Positives = 77/176 (43%), Gaps = 33/176 (18%)

Query: 56  IPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAA 115
           + + N    P H +      SPA    SP          + WMK K+   KT  +     
Sbjct: 173 LATYNNSLSPLHASHQEACRSPASETSSPAQT-------FDWMKVKRNPPKTGKVGEY-- 223

Query: 116 AATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVE 175
                                 G  G    +RT +T  QL ELEKEFHFNKYL R RRVE
Sbjct: 224 ----------------------GYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVE 261

Query: 176 IAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKT 231
           IAA L L E QVK+WFQNRRMK K++   KE            + EK EE  E+ +
Sbjct: 262 IAASLQLNETQVKIWFQNRRMKQKKRE--KEGLLPISPATPPGNDEKAEESSEKSS 315


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 60/166 (36%), Positives = 78/166 (46%), Gaps = 46/166 (27%)

Query: 49  PPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTA 108
           PPP    +P+  PG  P   A       P G  G+P   GA +P  Y WM+   AA    
Sbjct: 94  PPPDFSPVPA-PPGPGPGLLA------QPLGGPGTPSSPGAQRPTPYEWMRRSVAA---- 142

Query: 109 LLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRT------AYTNTQLLELEKEF 162
                                        G GGGS + RT       YT+ Q LELEKEF
Sbjct: 143 -----------------------------GGGGGSGKTRTKDKYRVVYTDHQRLELEKEF 173

Query: 163 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQ 208
           H+++Y+   R+ E+AA L LTERQVK+WFQNRR K ++  + K+ Q
Sbjct: 174 HYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQ 219


>gi|24497556 homeobox A7 [Homo sapiens]
          Length = 230

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 52/105 (49%), Positives = 64/105 (60%), Gaps = 14/105 (13%)

Query: 139 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 198
           SG   +R R  YT  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK 
Sbjct: 126 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 185

Query: 199 KRQTQCKENQNS---EGKCKSL-----------EDSEKVEEDEEE 229
           K++ + +    +   EG   S            ED ++ EEDEEE
Sbjct: 186 KKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE 230


>gi|23503237 homeobox B6 [Homo sapiens]
          Length = 224

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 48/91 (52%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 140 GGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK 199
           G   RR R  YT  Q LELEKEFH+N+YL R RR+EIA  L LTERQ+K+WFQNRRMK K
Sbjct: 143 GPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 202

Query: 200 RQTQCKENQNSEGKCKSLEDSEKVEEDEEEK 230
           +++            K L  S+   E+EEEK
Sbjct: 203 KES------------KLLSASQLSAEEEEEK 221


>gi|12056969 homeobox C8 [Homo sapiens]
          Length = 242

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 49/92 (53%), Positives = 59/92 (64%), Gaps = 10/92 (10%)

Query: 142 GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 201
           G R  R  Y+  Q LELEKEF FN YL R RR+E++  L LTERQVK+WFQNRRMK K+ 
Sbjct: 148 GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK- 206

Query: 202 TQCKENQNSEGKCKSLEDSEKVEE---DEEEK 230
                 +N++ K     D EKVEE   +EEEK
Sbjct: 207 ------ENNKDKLPGARDEEKVEEEGNEEEEK 232


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 67/172 (38%), Positives = 80/172 (46%), Gaps = 20/172 (11%)

Query: 62  GSHPRHGAGGRPKPSPAGSRGSPV-------PAGAL--QPP--EYPWMKEKKAAKKTALL 110
           G HP    GG   P+ A   G PV        A AL  Q P   Y + + + A       
Sbjct: 140 GLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPAD 199

Query: 111 PAAAAAAT-------AAATGPACLSHKESLEIADGSG--GGSRRLRTAYTNTQLLELEKE 161
           P    A T        A+T    L           S   G  RR RTA+T+ QLLELE +
Sbjct: 200 PIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQ 259

Query: 162 FHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGK 213
           F  NKYL RP+R E+A  L LTE QVK+WFQNRRMK KR  + KE    E +
Sbjct: 260 FKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAE 311


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,133,033
Number of Sequences: 37866
Number of extensions: 977237
Number of successful extensions: 8766
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 325
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 7017
Number of HSP's gapped (non-prelim): 1989
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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