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Search of human proteins with 18699730
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
(515 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 1033 0.0
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 515 e-146
gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 182 8e-46
gi|109288010 solute carrier family 16, member 3 [Homo sapiens] 181 1e-45
gi|109288012 solute carrier family 16, member 3 [Homo sapiens] 181 1e-45
gi|4759112 solute carrier family 16, member 3 [Homo sapiens] 181 1e-45
gi|23503293 solute carrier family 16, member 11 [Homo sapiens] 177 2e-44
gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 177 3e-44
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 174 2e-43
gi|157041233 solute carrier family 16 (monocarboxylic acid trans... 166 6e-41
gi|115583685 solute carrier family 16, member 1 [Homo sapiens] 154 2e-37
gi|4759116 solute carrier family 16, member 5 [Homo sapiens] 152 7e-37
gi|40789261 solute carrier family 16, member 6 [Homo sapiens] 130 3e-30
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 125 9e-29
gi|169217968 PREDICTED: similar to solute carrier family 16, mem... 123 4e-28
gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 116 6e-26
gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 92 9e-19
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 41 0.002
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 41 0.002
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 40 0.004
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 40 0.004
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 39 0.011
gi|14043024 BCL2-associated athanogene 3 [Homo sapiens] 39 0.015
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 39 0.015
gi|19924099 synapsin I isoform Ia [Homo sapiens] 39 0.015
gi|19924097 synapsin I isoform Ib [Homo sapiens] 39 0.015
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 39 0.015
gi|156416026 zinc finger protein 219 [Homo sapiens] 39 0.015
gi|156415998 zinc finger protein 219 [Homo sapiens] 39 0.015
gi|156415996 zinc finger protein 219 [Homo sapiens] 39 0.015
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 1033 bits (2671), Expect = 0.0
Identities = 515/515 (100%), Positives = 515/515 (100%)
Query: 1 MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE 60
MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE
Sbjct: 1 MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE 60
Query: 61 PPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSL 120
PPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSL
Sbjct: 61 PPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSL 120
Query: 121 SMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGC 180
SMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGC
Sbjct: 121 SMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGC 180
Query: 181 SFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIF 240
SFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIF
Sbjct: 181 SFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIF 240
Query: 241 MFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGI 300
MFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGI
Sbjct: 241 MFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGI 300
Query: 301 PLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVY 360
PLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVY
Sbjct: 301 PLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVY 360
Query: 361 LQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAI 420
LQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAI
Sbjct: 361 LQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAI 420
Query: 421 GFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREI 480
GFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREI
Sbjct: 421 GFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREI 480
Query: 481 SKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII 515
SKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII
Sbjct: 481 SKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII 515
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 515 bits (1326), Expect = e-146
Identities = 266/499 (53%), Positives = 336/499 (67%), Gaps = 18/499 (3%)
Query: 5 QEEPDSARGTSEAQPLG-PAPTGAAPP-PGPGPSDSPEAAVEKVEVELAGPATAEPHEPP 62
QE S SE +P P P PP P P P P+ A E+E EP P
Sbjct: 97 QEPVGSPEPESEPEPEPEPEPVPVPPPEPQPEPQPLPDPA-PLPELEFESERVHEPEPTP 155
Query: 63 -----------EPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMV 111
+PPEGG+GW+V+ AA WCNGS+FGI N+ G+L+ +LE K+ ++ V
Sbjct: 156 TVETRGTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEE--EKEKNRQV 213
Query: 112 -FKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYL 170
F+ AWVG+L+MGMIFFC PIVS+FTD GCR TA GAAV F+GL +SSF SS+ Y
Sbjct: 214 EFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYF 273
Query: 171 TYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGL 230
TYGI+F CGCSFA+QPSLVILGHYF++RLGL NG+V+AGSS+F++ P L+R+L D + L
Sbjct: 274 TYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKL 333
Query: 231 FYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKV 290
T +VL FMFVL L TYRPL S++D S +L R + +K FN +F+
Sbjct: 334 AQTFQVLSTFMFVLMLLSLTYRPLLPSSQDTPSKRGVRTLHQRF-LAQLRKYFNMRVFRQ 392
Query: 291 TAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIA 350
Y +WA GI A GYFVPYVHLMK+V E F + K V+L+CIG TSG+GRL+ G I+
Sbjct: 393 RTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHIS 452
Query: 351 DYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFEL 410
D +PG+KK+YLQVLSF +GLMSMMIPLC FG LI VCL +GL DG FI+IMAPIAFEL
Sbjct: 453 DSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFEL 512
Query: 411 VGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIP 470
VG SQAIG+LLG M++PM GPPIAGLLR+ G Y VAFY AGVPP+IG +L F+P
Sbjct: 513 VGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVP 572
Query: 471 WIHSKKQREISKTTGKEKM 489
+H + ++ + + K+KM
Sbjct: 573 LMHQRMFKKEQRDSSKDKM 591
>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
Length = 504
Score = 182 bits (461), Expect = 8e-46
Identities = 123/432 (28%), Positives = 199/432 (46%), Gaps = 33/432 (7%)
Query: 58 PHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWV 117
P PP+GGWGW+V+ A G +G A V F +++ F + D TAWV
Sbjct: 6 PRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSD-----TAWV 60
Query: 118 GSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFA 177
S+ + M++ P+ S+ FGCR + G + G++ +SF + + LYLT G++
Sbjct: 61 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG 120
Query: 178 CGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVL 237
G + +QPSL++LG YF++R L NG+ AGS VF L L + L++ G +L
Sbjct: 121 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL 180
Query: 238 CIFMFVLFLAGFTYRP----------------LATSTKDKESGGSGSSL-FSRKKFSPPK 280
+ G RP + + E+ G+G L + + P +
Sbjct: 181 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR 240
Query: 281 KIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSG 340
++ + A+ A+AV+AV L G FVP + L+ + + + + +L +G
Sbjct: 241 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI 300
Query: 341 VGRLLFG------RIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGL 394
V R G R+ +VP YL L+ GL + +GAL+A C+ GL
Sbjct: 301 VARPACGALAGLARLRPHVP-----YLFSLALLANGLTDLSSARARSYGALVAFCVAFGL 355
Query: 395 FDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYL 454
G ++ + VGA A+G +L + + +GPP AG L D L +Y++ FYL
Sbjct: 356 SYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYL 415
Query: 455 AGVPPLIGGAVL 466
AG + G +
Sbjct: 416 AGSEVALAGVFM 427
>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 181 bits (460), Expect = 1e-45
Identities = 120/423 (28%), Positives = 192/423 (45%), Gaps = 27/423 (6%)
Query: 50 LAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDK 109
+ G E + P+GGWGW V+ G + A V F +++ FG D
Sbjct: 1 MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSD- 59
Query: 110 MVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLY 169
TAW+ S+ + M++ P+ SV + FGCR +VG +G++++SF SI +Y
Sbjct: 60 ----TAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVY 115
Query: 170 LTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVG 229
LT G+I G + +QPSL++L YF KR + NG+ AGS VF L L ++L D G
Sbjct: 116 LTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYG 175
Query: 230 LFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFK 289
+L + + RPL + + GSG P +++ + ++F+
Sbjct: 176 WRGGFLILGGLLLNCCVCAALMRPLVVTAQP----GSGPP-------RPSRRLLDLSVFR 224
Query: 290 VTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGR- 348
+ ++AV + + G FVP V ++ + + + +L +G +F R
Sbjct: 225 DRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID-----IFARP 279
Query: 349 IADYVPGVKK-----VYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIM 403
A +V G+ K VYL S FF GL + +G L+ C+ G+ G ++
Sbjct: 280 AAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQ 339
Query: 404 APIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGG 463
+ +VG S AIG +L ++ + VGPP G L D Y F LAG L
Sbjct: 340 FEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSS 399
Query: 464 AVL 466
+L
Sbjct: 400 LIL 402
>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 181 bits (460), Expect = 1e-45
Identities = 120/423 (28%), Positives = 192/423 (45%), Gaps = 27/423 (6%)
Query: 50 LAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDK 109
+ G E + P+GGWGW V+ G + A V F +++ FG D
Sbjct: 1 MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSD- 59
Query: 110 MVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLY 169
TAW+ S+ + M++ P+ SV + FGCR +VG +G++++SF SI +Y
Sbjct: 60 ----TAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVY 115
Query: 170 LTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVG 229
LT G+I G + +QPSL++L YF KR + NG+ AGS VF L L ++L D G
Sbjct: 116 LTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYG 175
Query: 230 LFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFK 289
+L + + RPL + + GSG P +++ + ++F+
Sbjct: 176 WRGGFLILGGLLLNCCVCAALMRPLVVTAQP----GSGPP-------RPSRRLLDLSVFR 224
Query: 290 VTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGR- 348
+ ++AV + + G FVP V ++ + + + +L +G +F R
Sbjct: 225 DRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID-----IFARP 279
Query: 349 IADYVPGVKK-----VYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIM 403
A +V G+ K VYL S FF GL + +G L+ C+ G+ G ++
Sbjct: 280 AAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQ 339
Query: 404 APIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGG 463
+ +VG S AIG +L ++ + VGPP G L D Y F LAG L
Sbjct: 340 FEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSS 399
Query: 464 AVL 466
+L
Sbjct: 400 LIL 402
>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 181 bits (460), Expect = 1e-45
Identities = 120/423 (28%), Positives = 192/423 (45%), Gaps = 27/423 (6%)
Query: 50 LAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDK 109
+ G E + P+GGWGW V+ G + A V F +++ FG D
Sbjct: 1 MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSD- 59
Query: 110 MVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLY 169
TAW+ S+ + M++ P+ SV + FGCR +VG +G++++SF SI +Y
Sbjct: 60 ----TAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVY 115
Query: 170 LTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVG 229
LT G+I G + +QPSL++L YF KR + NG+ AGS VF L L ++L D G
Sbjct: 116 LTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYG 175
Query: 230 LFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFK 289
+L + + RPL + + GSG P +++ + ++F+
Sbjct: 176 WRGGFLILGGLLLNCCVCAALMRPLVVTAQP----GSGPP-------RPSRRLLDLSVFR 224
Query: 290 VTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGR- 348
+ ++AV + + G FVP V ++ + + + +L +G +F R
Sbjct: 225 DRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID-----IFARP 279
Query: 349 IADYVPGVKK-----VYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIM 403
A +V G+ K VYL S FF GL + +G L+ C+ G+ G ++
Sbjct: 280 AAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQ 339
Query: 404 APIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGG 463
+ +VG S AIG +L ++ + VGPP G L D Y F LAG L
Sbjct: 340 FEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSS 399
Query: 464 AVL 466
+L
Sbjct: 400 LIL 402
>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
Length = 471
Score = 177 bits (450), Expect = 2e-44
Identities = 122/424 (28%), Positives = 199/424 (46%), Gaps = 23/424 (5%)
Query: 53 PATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVF 112
P TA +P PP+GGWGW+V AA NG +G+ + G+ F + E F D+
Sbjct: 21 PQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHF-----DRSAQ 75
Query: 113 KTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTY 172
TAW+ +L++ + P+ S + +G R +VG + +G + S+F S + LYL
Sbjct: 76 DTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGL 135
Query: 173 GIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFY 232
G++ G + + P+L L YF +R L G+ G+ ++LL L++L+D+ G
Sbjct: 136 GLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRG 195
Query: 233 TLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTA 292
L +L L G PL S P ++F A
Sbjct: 196 ALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRS------------PLAALGLSLFTRRA 243
Query: 293 YAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADY 352
++++A+G L GYFVPYVHL H +R +V+ + RL+ G +AD
Sbjct: 244 FSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQ 303
Query: 353 ----VPGVKKVY--LQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPI 406
+P + V+ L L + +GL+ ++ S G L+A + GL G + ++ +
Sbjct: 304 GWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGV 363
Query: 407 AFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVL 466
LVG V QA G ++ MS+ +GPP++G LRD+ G + +F L+G L G +
Sbjct: 364 LPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIY 423
Query: 467 CFIP 470
+P
Sbjct: 424 IGLP 427
>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
Length = 426
Score = 177 bits (448), Expect = 3e-44
Identities = 114/412 (27%), Positives = 195/412 (47%), Gaps = 29/412 (7%)
Query: 63 EPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSM 122
EPP+GGWGW+V+L+A + + VFG+ + GV FV + F ++ + +W+ S+ +
Sbjct: 6 EPPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAF-----EEQAARVSWIASIGI 60
Query: 123 GMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSF 182
+ F P+ S + FG R + G + +G++ +SF +S+ LYL+ G++ G +
Sbjct: 61 AVQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWAL 120
Query: 183 AYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMF 242
+ P+L L YF +R L G+ G + + + L+ +L ++
Sbjct: 121 TFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSL 180
Query: 243 VLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPL 302
L G RP + +D GG + L S P + + V + L
Sbjct: 181 HLVACGALLRP-PSLAEDPAVGGPRAQLTSLLHHGP--------------FLRYTVALTL 225
Query: 303 ALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQ 362
GYF+PY+HL+ H+ + D +L + ++ VGR++ G + D VPG L
Sbjct: 226 INTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPG-PVTRLL 284
Query: 363 VLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAF----ELVGAQDVSQ 418
+L G+ + P+ AL+A+ + G G +AP+AF EL+G + +
Sbjct: 285 MLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGA----LAPLAFSVLPELIGTRRIYC 340
Query: 419 AIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIP 470
+G L SI +GPP++G LRD G+Y +F +AG L G +L +P
Sbjct: 341 GLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLP 392
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 174 bits (441), Expect = 2e-43
Identities = 127/462 (27%), Positives = 211/462 (45%), Gaps = 29/462 (6%)
Query: 58 PHEPP--EPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTA 115
P PP PP+GGWGW+V+ AA G + A V F + + F + + A
Sbjct: 5 PSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSE-----IA 59
Query: 116 WVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGII 175
W+ S+ + +++ P+ SV + +G R + G + +G++ +SF SS+ LYLT G I
Sbjct: 60 WISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFI 119
Query: 176 FACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLR 235
G +F QP+L I+G YF ++ + NG+ AGS VF L + L ++ G +
Sbjct: 120 TGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFL 179
Query: 236 VLCIFMFVLFLAGFTYRPLA---TSTKDKESGGSGSSLFSRKKFSPPK-------KIFNF 285
+L + +AG RPL T++K K G S KK K K +F
Sbjct: 180 ILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDF 239
Query: 286 AIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLL 345
++FK + ++ G + G+F P + L + ++ DE + +L + R
Sbjct: 240 SLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPS 299
Query: 346 FGRIAD--YV-PGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISI 402
G IA+ Y+ P ++ Y + F G+ ++ PL + +L+ + GL G S+
Sbjct: 300 VGLIANSKYIRPRIQ--YFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSV 357
Query: 403 MAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAG------ 456
+ +LVGA S A+G + P+ +GPP+AG L D G Y + G
Sbjct: 358 LFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAA 417
Query: 457 -VPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQN 497
V LIG A+ + K++ KT E + K +++
Sbjct: 418 SVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSED 459
>gi|157041233 solute carrier family 16 (monocarboxylic acid
transporters), member 12 [Homo sapiens]
Length = 486
Score = 166 bits (419), Expect = 6e-41
Identities = 108/437 (24%), Positives = 200/437 (45%), Gaps = 27/437 (6%)
Query: 64 PPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMG 123
PP+GGWGW+++ + + FV +T+ ++D +TAW+ S+
Sbjct: 12 PPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEF-QTYFTQD----YAQTAWIHSIVDC 66
Query: 124 MIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFA 183
+ C P+ SV ++ C+ ++G + GL+ SSF +S++ LYLT G++ G +
Sbjct: 67 VTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALC 126
Query: 184 YQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFV 243
Y P++ ++G YF +R L GI +GS + T +L ++++LI+ L +L F+
Sbjct: 127 YSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLN 186
Query: 244 LFLAGFTYRPLATS---TKDKESGGSGSSLFSRKKFSPPKKIF--------------NFA 286
L + G RP+ T +++ + K+ SP + ++
Sbjct: 187 LCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYS 246
Query: 287 IFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLF 346
++ + V AV + +G +V+L+ + + ++ +GV +G + F
Sbjct: 247 FLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITF 306
Query: 347 GRIADYVPGVKKVYLQVLSFFFI---GLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIM 403
G + D K Y V F + GL + +P+ L+ G FDG +++++
Sbjct: 307 GWLTD--RRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLI 364
Query: 404 APIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGG 463
+ E+VG +S A+G + ++P V PPIAG L D GSY AF L G +
Sbjct: 365 PVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSS 424
Query: 464 AVLCFIPWIHSKKQREI 480
+L F I ++ ++
Sbjct: 425 VLLGFARLIKRMRKTQL 441
>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
Length = 500
Score = 154 bits (388), Expect = 2e-37
Identities = 115/458 (25%), Positives = 198/458 (43%), Gaps = 38/458 (8%)
Query: 64 PPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMG 123
PP+GGWGW V++ A G + + V F + F + + +W+ S+ +
Sbjct: 13 PPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSE-----VSWISSIMLA 67
Query: 124 MIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFA 183
+++ PI S+ + +G R +VG + GL+++SF ++++ LY+ G+I G +F
Sbjct: 68 VMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFN 127
Query: 184 YQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFV 243
P+L ++G YF KR L NG+ AGS VF L L +V G + +L +
Sbjct: 128 LNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLN 187
Query: 244 LFLAGFTYRPL----ATSTKDK------ESGGSG---------SSLFSRKKFSPPKKIF- 283
+AG RP+ + KDK ++G SG + L R + +F
Sbjct: 188 CCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQ 247
Query: 284 ------NFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGV 337
+ +F + ++ G + FG F P V L + + + +L +
Sbjct: 248 TINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAF 307
Query: 338 TSGVGRLLFGRIADYVPGVKKV-YLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFD 396
V R G +A+ P ++ Y S G+ M+ PL + + + C+ G F
Sbjct: 308 VDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTY---VGFCVYAGFFG 364
Query: 397 ---GCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFY 453
G S++ +LVG Q S A+G + P+ +GPP+ G L D G Y ++
Sbjct: 365 FAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYW 424
Query: 454 LAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEK 491
GV +I G L I+ + + K ++K K
Sbjct: 425 ACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESK 462
>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
Length = 505
Score = 152 bits (384), Expect = 7e-37
Identities = 114/472 (24%), Positives = 205/472 (43%), Gaps = 41/472 (8%)
Query: 63 EPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSM 122
E +G W W+V+LA M G G G+ F + F + + + T+W S+
Sbjct: 6 ERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSE-----TSWFPSILT 60
Query: 123 GMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSF 182
++ P+ S+ FGCR T ++G + +G+++SSF ++ LY T G I G F
Sbjct: 61 AVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 120
Query: 183 AYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMF 242
++Q S+ +LG YF +R L N + + G S+ L PLL R L++++G T V
Sbjct: 121 SFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFL 180
Query: 243 VLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPP--------------KKIFNFAIF 288
+ G RP+ATS + K+ PP + I F
Sbjct: 181 HCCICGAIIRPVATSVAPET-----------KECPPPPPETPALGCLAACGRTIQRHLAF 229
Query: 289 KV----TAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRL 344
+ T Y V+ +G+ ++ G+ +P V L+ + DE+ +++ IG ++ R
Sbjct: 230 DILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRP 289
Query: 345 LFGRIADYVPGVK-KVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIM 403
L G +A + YL L+ GL +++ F L+ CL + +++
Sbjct: 290 LAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALI 349
Query: 404 APIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGG 463
+ ++V +A+G + + PP+AGLL D ++ FY++ LI
Sbjct: 350 FQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSF-FLISA 408
Query: 464 AVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII 515
A+ + +K+ + + + +E+ L L + G K+ S I+
Sbjct: 409 ALFMGGSFYALQKKEQGKQAVAADALERDL-----FLEAKDGPGKQRSPEIM 455
>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
Length = 523
Score = 130 bits (327), Expect = 3e-30
Identities = 98/461 (21%), Positives = 189/461 (40%), Gaps = 60/461 (13%)
Query: 63 EPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSM 122
E P+GGWGW V ++ + +GI GV F ++++F + + +W+ S+ +
Sbjct: 17 EVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNS-----RISWIISICV 71
Query: 123 GMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSF 182
++ F P+ +V ++ FG R ++G + G++++SF + +Y+ GII G F
Sbjct: 72 FVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCF 131
Query: 183 AYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMF 242
++ P++ IL YF KR +V + + G + L + +G Y+L + +
Sbjct: 132 SFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQL 191
Query: 243 VLFLAGFTYRPL-------------------------ATSTKDKESGGSGSSLFSRKKFS 277
+ + G RP+ + +S SG L + K
Sbjct: 192 NIVIFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNV 251
Query: 278 P--------PK-------------------KIFNFAIFKVTAYAVWAVGIPLALFGYFVP 310
P PK + +F+I K ++ +A+ A G+F P
Sbjct: 252 PTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAP 311
Query: 311 YVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIG 370
++++ D+ +L + + GR+ G + + P ++K+Y++++ +
Sbjct: 312 SLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREP-IRKIYIELICVILLT 370
Query: 371 LMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFE--LVGAQDVSQAIGFLLGFMS 428
+ + F L++ + G G P+ E +VG + +S A G + S
Sbjct: 371 VSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQS 430
Query: 429 IPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFI 469
I GPP+AGLL D+ Y AFY + L +
Sbjct: 431 IAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALV 471
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 125 bits (314), Expect = 9e-29
Identities = 67/213 (31%), Positives = 111/213 (52%), Gaps = 5/213 (2%)
Query: 52 GPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMV 111
GP + +P +GGW W+++L++ + + + G Q A GVL V LE F
Sbjct: 15 GPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRG---- 70
Query: 112 FKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLT 171
TAWV SLSMG+ P + +F + GCR+TA++G V +G + S++ +++ L++T
Sbjct: 71 -LTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFIT 129
Query: 172 YGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLF 231
+G+ G AY P++V++G YF+KR L G+ T G+ T L+ +LL+ L G
Sbjct: 130 FGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWR 189
Query: 232 YTLRVLCIFMFVLFLAGFTYRPLATSTKDKESG 264
+ + L + G RPL+ + G
Sbjct: 190 NAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPG 222
Score = 79.0 bits (193), Expect = 1e-14
Identities = 54/187 (28%), Positives = 93/187 (49%), Gaps = 6/187 (3%)
Query: 292 AYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCI-GVTSGVGRLLFGRIA 350
A+ WA+ A + +P++HL + VN E+N L I + G+++ G IA
Sbjct: 318 AFIFWAL---FAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIA 374
Query: 351 DYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFEL 410
D +P + + +L+ F + L ++PL + L +C ++G G F S+M + +L
Sbjct: 375 D-LPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYF-SLMPVVTEDL 432
Query: 411 VGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIP 470
VG + ++ A G ++ I +GPP AG + D YD +FY+ G+ +IG L P
Sbjct: 433 VGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQP 492
Query: 471 WIHSKKQ 477
I +Q
Sbjct: 493 CIRIIEQ 499
>gi|169217968 PREDICTED: similar to solute carrier family 16, member
5 [Homo sapiens]
Length = 453
Score = 123 bits (309), Expect = 4e-28
Identities = 98/405 (24%), Positives = 177/405 (43%), Gaps = 36/405 (8%)
Query: 130 PIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLV 189
P+ S+ FGCR T ++G + +G+++SSF ++ LY T G I G F++Q S+
Sbjct: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
Query: 190 ILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGF 249
+LG YF +R L N + + G S+ L PLL R L++++G T V + G
Sbjct: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
Query: 250 TYRPLATSTKDKESGGSGSSLFSRKKFSPP--------------KKIFNFAIFKV----T 291
RP+ATS + K+ PP + I F + T
Sbjct: 136 IIRPVATSVAPET-----------KECPPPPPETPALGCLAACGRTIQRHLAFDILRHNT 184
Query: 292 AYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIAD 351
Y V+ +G+ ++ G+ +P V L+ + DE+ +++ IG ++ R L G +A
Sbjct: 185 GYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAG 244
Query: 352 YVPGVK-KVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFEL 410
+ YL L+ GL +++ F L+ CL + +++ + ++
Sbjct: 245 RPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDI 304
Query: 411 VGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIP 470
V +A+G + + PP+AGLL D ++ FY++ LI A+
Sbjct: 305 VPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSF-FLISAALFMGGS 363
Query: 471 WIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII 515
+ +K+ + + + +E+ L L + G K+ S I+
Sbjct: 364 FYALQKKEQGKQAVAADALERDL-----FLEAKDGPGKQRSPEIM 403
>gi|34916028 solute carrier family 16 (monocarboxylic acid
transporters), member 9 [Homo sapiens]
Length = 509
Score = 116 bits (290), Expect = 6e-26
Identities = 65/198 (32%), Positives = 98/198 (49%), Gaps = 5/198 (2%)
Query: 60 EPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGS 119
E + P+GGWGW+++ + +G A GVL++ L+ FG KTAWVGS
Sbjct: 2 ELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKG-----KTAWVGS 56
Query: 120 LSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACG 179
L+ G+ P+ S+ FG R + + GLM SSF +I L+ +YGI+ G
Sbjct: 57 LASGVGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLG 116
Query: 180 CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCI 239
C Y ++ I YF R GL G+++ GSSV + L R+L++ GL L ++
Sbjct: 117 CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGA 176
Query: 240 FMFVLFLAGFTYRPLATS 257
+ G RPL +S
Sbjct: 177 LALNILACGSLMRPLQSS 194
Score = 83.2 bits (204), Expect = 5e-16
Identities = 58/184 (31%), Positives = 95/184 (51%), Gaps = 7/184 (3%)
Query: 286 AIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVL---MCIGVTSGVG 342
A+FK ++ + I L G F P + LM+ V R + K +E ++ IG+ + VG
Sbjct: 299 ALFKNKVFSALFIAILLFDIGGFPPSL-LMEDV-ARSSNVKEEEFIMPLISIIGIMTAVG 356
Query: 343 RLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISI 402
+LL G +AD+ + +YL V + +GL IP + L + I+G G + SI
Sbjct: 357 KLLLGILADF-KWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW-SI 414
Query: 403 MAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIG 462
+ + VG + ++ A G L+ F + ++GPPI G D +YD+AFY +G L+G
Sbjct: 415 FPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474
Query: 463 GAVL 466
G +L
Sbjct: 475 GFIL 478
>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
Length = 487
Score = 92.4 bits (228), Expect = 9e-19
Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 6/161 (3%)
Query: 66 EGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMI 125
+GGWGW++++ N V G+ + FV E F + + W+GS+ +
Sbjct: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSE-----QIGWIGSIMSSLR 70
Query: 126 FFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQ 185
F P+V++ D+ G + T+++GA V G + SS+ +SI L +T G++ G +F YQ
Sbjct: 71 FCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQ 130
Query: 186 PSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLID 226
+ V+ YFKKRL L I +G + T LL + LID
Sbjct: 131 VAAVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLID 170
Score = 82.8 bits (203), Expect = 7e-16
Identities = 44/191 (23%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Query: 280 KKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTS 339
K++F+ ++F+ + ++ L+ YF+P HL+ D + ++ G+
Sbjct: 288 KQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILE 347
Query: 340 GVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCF 399
V +++ G +AD +KK + G+ +++ PL + F L+ + +F G +
Sbjct: 348 TVSQIISGWVADQ-NWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGY 406
Query: 400 ISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPP 459
++++ P+ +L V++ +G F + + GPPIAG L D +Y+ +FY +G+
Sbjct: 407 LALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICY 466
Query: 460 LIGGAVLCFIP 470
L+ F+P
Sbjct: 467 LLSSVSFFFVP 477
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Query: 9 DSARGTSEAQPLGPAPTGA-APPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPP 65
++A+ T + P PA GA PPPGP P+ PE E A AT P PP PP
Sbjct: 740 EAAKDTGQNGPKPPATLGADGPPPGP-PTPPPEDIPAPTEPTPASEATGAPTPPPAPP 796
Score = 30.4 bits (67), Expect = 4.0
Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 2/60 (3%)
Query: 8 PDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAV--EKVEVELAGPATAEPHEPPEPP 65
P+ +E P A PPP P +P V E+ E E A E E +PP
Sbjct: 770 PEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPP 829
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Query: 9 DSARGTSEAQPLGPAPTGA-APPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPP 65
++A+ T + P PA GA PPPGP P+ PE E A AT P PP PP
Sbjct: 757 EAAKDTGQNGPKPPATLGADGPPPGP-PTPPPEDIPAPTEPTPASEATGAPTPPPAPP 813
Score = 30.4 bits (67), Expect = 4.0
Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 2/60 (3%)
Query: 8 PDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAV--EKVEVELAGPATAEPHEPPEPP 65
P+ +E P A PPP P +P V E+ E E A E E +PP
Sbjct: 787 PEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPP 846
Score = 30.4 bits (67), Expect = 4.0
Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 4 SQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVE----KVEVELAGPATAEPH 59
S +E D A G + + L P P+ P P + SP+ ++ K P + H
Sbjct: 922 SADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVH 981
Query: 60 EPP 62
EPP
Sbjct: 982 EPP 984
>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
sapiens]
Length = 533
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 1 MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE 60
M+L EP AR AQ T PP GP + P+A + PA A
Sbjct: 45 MLLVLSEPGPAR--PRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPT 102
Query: 61 PPEPPEGGWG 70
P E P+ GWG
Sbjct: 103 PEEGPDAGWG 112
>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
sapiens]
Length = 539
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 1 MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE 60
M+L EP AR AQ T PP GP + P+A + PA A
Sbjct: 45 MLLVLSEPGPAR--PRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPT 102
Query: 61 PPEPPEGGWG 70
P E P+ GWG
Sbjct: 103 PEEGPDAGWG 112
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 38.9 bits (89), Expect = 0.011
Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 8 PDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE------- 60
PD EA PAP PPG PS P A++ + E E GPA E H
Sbjct: 1170 PDQHTHPKEAATDPPAPRTPPEPPGSPPSSPPPASLGRPEGEEEGPAEPEEHSVRICMSP 1229
Query: 61 PPEPPE 66
PEP E
Sbjct: 1230 GPEPGE 1235
>gi|14043024 BCL2-associated athanogene 3 [Homo sapiens]
Length = 575
Score = 38.5 bits (88), Expect = 0.015
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Query: 3 LSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPH-EP 61
+SQ+ P + P P P PPP PGPS P + E A P+TA P
Sbjct: 351 VSQKPPPPSEKVEVKVPPAPVP---CPPPSPGPSAVPSSPKSVATEERAAPSTAPAEATP 407
Query: 62 PEPPE 66
P+P E
Sbjct: 408 PKPGE 412
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 38.5 bits (88), Expect = 0.015
Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
Query: 22 PAPTGAAPPP----GPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGG 68
P P+GA PPP GP + P A E+ E A P P PP PP G
Sbjct: 801 PPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPG 851
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 38.5 bits (88), Expect = 0.015
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 7/67 (10%)
Query: 5 QEEPDSARGTSEAQPLGPAPTGAAP------PPGPGPSDSPEAAV-EKVEVELAGPATAE 57
Q+ P A T +A GP P P P GPGP+ P+ + +K ++ PATA
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAA 651
Query: 58 PHEPPEP 64
PP P
Sbjct: 652 AGGPPHP 658
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 9/70 (12%)
Query: 8 PDSARGTSEAQPLGPAPTGAAP-------PPG--PGPSDSPEAAVEKVEVELAGPATAEP 58
P + R TS + P P +GA P PP PGP+ A + V GP T +
Sbjct: 561 PQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQ 620
Query: 59 HEPPEPPEGG 68
P P G
Sbjct: 621 PRPSGPGPAG 630
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 38.5 bits (88), Expect = 0.015
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 7/67 (10%)
Query: 5 QEEPDSARGTSEAQPLGPAPTGAAP------PPGPGPSDSPEAAV-EKVEVELAGPATAE 57
Q+ P A T +A GP P P P GPGP+ P+ + +K ++ PATA
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAA 651
Query: 58 PHEPPEP 64
PP P
Sbjct: 652 AGGPPHP 658
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 9/70 (12%)
Query: 8 PDSARGTSEAQPLGPAPTGAAP-------PPG--PGPSDSPEAAVEKVEVELAGPATAEP 58
P + R TS + P P +GA P PP PGP+ A + V GP T +
Sbjct: 561 PQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQ 620
Query: 59 HEPPEPPEGG 68
P P G
Sbjct: 621 PRPSGPGPAG 630
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 38.5 bits (88), Expect = 0.015
Identities = 19/55 (34%), Positives = 24/55 (43%)
Query: 14 TSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGG 68
+S A P P +GA P GPGP+ +P AV P P PP+ G
Sbjct: 128 SSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAG 182
Score = 35.4 bits (80), Expect = 0.13
Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 7/70 (10%)
Query: 8 PDSARGTSEAQPLGPAPTGAAPP-PGPGPSDSPEAAVEK------VEVELAGPATAEPHE 60
P S T+ Q GP P AA P PGPGP P K GP + P
Sbjct: 170 PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGG 229
Query: 61 PPEPPEGGWG 70
P+PP G G
Sbjct: 230 HPKPPHRGGG 239
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/48 (31%), Positives = 22/48 (45%), Gaps = 1/48 (2%)
Query: 19 PLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPE 66
P+GP P + P P P P P ++ + P PH+PP P+
Sbjct: 46 PMGPGPGQSGPKP-PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ 92
Score = 29.6 bits (65), Expect = 6.9
Identities = 23/74 (31%), Positives = 28/74 (37%), Gaps = 10/74 (13%)
Query: 4 SQEEPDSARGTSEAQP-LGPAPTGA------APPPGPGPSDSPEAAVEKVEVELAG---P 53
S P + TS A P GP PT + PPG P P + V + G P
Sbjct: 128 SSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPP 187
Query: 54 ATAEPHEPPEPPEG 67
A P P P +G
Sbjct: 188 PAAVPGPGPGPKQG 201
>gi|156416026 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 38.5 bits (88), Expect = 0.015
Identities = 24/55 (43%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 14 TSEAQPLGPAPTGAAPPPGPGPSD--SPEAAVEKVEVELAGPATAEPHEPPEPPE 66
TS A P P P PPP P P PE E PA A P EPP PPE
Sbjct: 222 TSAAPPPQPQPQ---PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPE 273
>gi|156415998 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 38.5 bits (88), Expect = 0.015
Identities = 24/55 (43%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 14 TSEAQPLGPAPTGAAPPPGPGPSD--SPEAAVEKVEVELAGPATAEPHEPPEPPE 66
TS A P P P PPP P P PE E PA A P EPP PPE
Sbjct: 222 TSAAPPPQPQPQ---PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPE 273
>gi|156415996 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 38.5 bits (88), Expect = 0.015
Identities = 24/55 (43%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 14 TSEAQPLGPAPTGAAPPPGPGPSD--SPEAAVEKVEVELAGPATAEPHEPPEPPE 66
TS A P P P PPP P P PE E PA A P EPP PPE
Sbjct: 222 TSAAPPPQPQPQ---PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPE 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.142 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,568,860
Number of Sequences: 37866
Number of extensions: 1047241
Number of successful extensions: 13441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 322
Number of HSP's that attempted gapping in prelim test: 10953
Number of HSP's gapped (non-prelim): 2400
length of query: 515
length of database: 18,247,518
effective HSP length: 107
effective length of query: 408
effective length of database: 14,195,856
effective search space: 5791909248
effective search space used: 5791909248
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.