Guide to the Human Genome
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Search of human proteins with 183396804

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|183396804 Regulation of nuclear pre-mRNA domain containing 2
[Homo sapiens]
         (1461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ...  2931   0.0  
gi|21361709 regulation of nuclear pre-mRNA domain containing 1A ...   119   2e-26
gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B ...   108   4e-23
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        92   4e-18
gi|91982772 mucin 17 [Homo sapiens]                                    90   1e-17
gi|151301154 mucin 6, gastric [Homo sapiens]                           82   4e-15
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    80   1e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni...    80   1e-14
gi|116284392 mucin 2 precursor [Homo sapiens]                          77   9e-14
gi|167736355 mucin 4 isoform a [Homo sapiens]                          77   9e-14
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    72   4e-12
gi|83367077 mucin 16 [Homo sapiens]                                    71   7e-12
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    71   7e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   70   1e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   70   1e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   70   1e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    70   1e-11
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              70   1e-11
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        69   3e-11
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    69   3e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          69   4e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          69   4e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          69   4e-11
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...    68   6e-11
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            68   7e-11
gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap...    67   1e-10
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    66   2e-10
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    65   4e-10
gi|239508973 PREDICTED: similar to Mucin-3A [Homo sapiens]             65   4e-10
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    65   5e-10

>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 [Homo
            sapiens]
          Length = 1461

 Score = 2931 bits (7598), Expect = 0.0
 Identities = 1461/1461 (100%), Positives = 1461/1461 (100%)

Query: 1    MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVY 60
            MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVY
Sbjct: 1    MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVY 60

Query: 61   HWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSV 120
            HWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSV
Sbjct: 61   HWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSV 120

Query: 121  ERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAAL 180
            ERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAAL
Sbjct: 121  ERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAAL 180

Query: 181  KSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFS 240
            KSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFS
Sbjct: 181  KSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFS 240

Query: 241  KEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVN 300
            KEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVN
Sbjct: 241  KEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVN 300

Query: 301  NLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPE 360
            NLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPE
Sbjct: 301  NLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPE 360

Query: 361  PVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVP 420
            PVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVP
Sbjct: 361  PVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVP 420

Query: 421  VTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSP 480
            VTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSP
Sbjct: 421  VTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSP 480

Query: 481  GTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLS 540
            GTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLS
Sbjct: 481  GTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLS 540

Query: 541  SLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSE 600
            SLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSE
Sbjct: 541  SLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSE 600

Query: 601  VSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE 660
            VSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE
Sbjct: 601  VSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE 660

Query: 661  SESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNI 720
            SESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNI
Sbjct: 661  SESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNI 720

Query: 721  DGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPR 780
            DGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPR
Sbjct: 721  DGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPR 780

Query: 781  ELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSG 840
            ELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSG
Sbjct: 781  ELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSG 840

Query: 841  PPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSS 900
            PPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSS
Sbjct: 841  PPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSS 900

Query: 901  ENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQK 960
            ENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQK
Sbjct: 901  ENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQK 960

Query: 961  QYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKP 1020
            QYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKP
Sbjct: 961  QYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKP 1020

Query: 1021 SDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEE 1080
            SDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEE
Sbjct: 1021 SDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEE 1080

Query: 1081 KGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDN 1140
            KGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDN
Sbjct: 1081 KGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDN 1140

Query: 1141 GPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLE 1200
            GPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLE
Sbjct: 1141 GPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLE 1200

Query: 1201 HGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPG 1260
            HGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPG
Sbjct: 1201 HGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPG 1260

Query: 1261 EHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGA 1320
            EHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGA
Sbjct: 1261 EHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGA 1320

Query: 1321 VAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLG 1380
            VAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLG
Sbjct: 1321 VAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLG 1380

Query: 1381 PPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPR 1440
            PPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPR
Sbjct: 1381 PPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPR 1440

Query: 1441 PPFARGPPFFAPKRPFFPPRY 1461
            PPFARGPPFFAPKRPFFPPRY
Sbjct: 1441 PPFARGPPFFAPKRPFFPPRY 1461


>gi|21361709 regulation of nuclear pre-mRNA domain containing 1A
           [Homo sapiens]
          Length = 312

 Score =  119 bits (298), Expect = 2e-26
 Identities = 84/300 (28%), Positives = 143/300 (47%), Gaps = 15/300 (5%)

Query: 24  ESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLAND 83
           E++L++K   ++N+ +S+Q LS W I ++KH   IV  W + LR++    +L   YLAND
Sbjct: 6   EAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLAND 65

Query: 84  VIQNCKRKNAIIFRESFADVLPEAAALVK---DPSVSKSVERIFKIWEDRNVYPEEMIVA 140
           VIQN KRK    F + FA V+ EA   V    D S  K + R+  IWE+R+VY  +++  
Sbjct: 66  VIQNSKRKGP-EFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQ 124

Query: 141 LREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLY 200
           L++AL    K +K+  E +    N+      + + P   L            L+  L   
Sbjct: 125 LKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLD-----------LVRALQDL 173

Query: 201 KRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQ 260
           + +        ++++++ V+V     L  + DK  G++ SK  E+A   L ++   L  +
Sbjct: 174 ENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAE 233

Query: 261 VKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESP 320
           + +   LT  L +     +    E +     YK    RV+ ++K+L     +LPD    P
Sbjct: 234 IDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLP 293


>gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B
           [Homo sapiens]
          Length = 326

 Score =  108 bits (270), Expect = 4e-23
 Identities = 85/325 (26%), Positives = 151/325 (46%), Gaps = 22/325 (6%)

Query: 24  ESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLAND 83
           ES+L++K   ++N+ +S+Q LS W I ++KH   IV  W + LR++    +L   YLAND
Sbjct: 6   ESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLAND 65

Query: 84  VIQNCKRKNAIIFRESFADVLPEA---AALVKDPSVSKSVERIFKIWEDRNVYPEEMIVA 140
           VIQN KRK     RE F  VL +A    A   D    K +ER+  IW++R+VY  E I  
Sbjct: 66  VIQNSKRKGPEFTRE-FESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQ 124

Query: 141 LREALSTT----------FKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRS 190
           L+ ++  +           K+ K+  + + ++ +  +  S +  +P A           +
Sbjct: 125 LKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSA-------GPLLT 177

Query: 191 QALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKL 250
           + LI+ L   + +        ++++++  +V     L+ + DK   ++ SK  +EA   L
Sbjct: 178 EELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLL 237

Query: 251 EEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLK 310
            E+   L  ++++   L   L       +    E +     YK    RV  ++K+L    
Sbjct: 238 AEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHI 297

Query: 311 STLPDPEESPVPSPSMDAPSPTGSE 335
            +LPD    P  +  + AP P+  +
Sbjct: 298 QSLPDLSLLPNVTGGL-APLPSAGD 321


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 212/969 (21%), Positives = 352/969 (36%), Gaps = 127/969 (13%)

Query: 394  EKSAVSTSVPTK-PTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPN-LANV 451
            E S  S   P+  PT + S +S  T +  +  +T     PV T+ +PSPA +  + L   
Sbjct: 1854 ELSTTSHGSPSSTPTTHFSASS--TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 1911

Query: 452  DLAKISSILSSLTSVMKNT----GVSPASRPSPGTPT----SPSNLTSGL-------KTP 496
              A  SS  S+ T     +    G S  SR S  + T    SP + TS L        + 
Sbjct: 1912 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSS 1971

Query: 497  APATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEA 556
              +T T+H P ++  S       +  S+   T T   PA    S LL   T +P+    +
Sbjct: 1972 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI---SS 2028

Query: 557  ASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPG 616
             S  T+A P +TT   +  ++    + P  P +   SP S+TS  S  S    +    PG
Sbjct: 2029 GSMETTALPGSTTTPGLSEKSTTFHSSPRSPAT-TLSPASTTS--SGVSEESTTSHSRPG 2085

Query: 617  LPSTTFKLPSNSLGFTATHNTSPAAPP--TEVTICQSSEVSKPKLESESTSPSLEMKIHN 674
               TT    S +    + H+T+  + P  T+ T+  +S  +    +  +TS S       
Sbjct: 2086 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDT 2145

Query: 675  FLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPT 734
             L  +PG S   L+    S+   S+P  +H + F    TS+ I  ++ +      +G+P 
Sbjct: 2146 AL--SPG-STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI--VEASTRVHSSTGSPR 2200

Query: 735  QDEMMDKPTSSSVDTMSLLSKIISPGSST---PSSTRSPPPGRDESYPRELSNSVSTYRP 791
                    TS  +   S   +     + T   P ST + P     +Y R   ++ +T+ P
Sbjct: 2201 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 2260

Query: 792  FGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEK 851
                + S + + S           ++    +  TS + +             + +     
Sbjct: 2261 AS-STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 2319

Query: 852  KP----AKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLD--------- 898
             P    A +   SS  S TT   P   +     +E     + P S  + +          
Sbjct: 2320 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2379

Query: 899  SSENCDRLSSSPGLFGAF--------SVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQS 950
            S E+    SSSPG             SVRG EP +  S   S + + FT DS  + L++ 
Sbjct: 2380 SEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 2439

Query: 951  TTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFK 1010
            +T     P       P  +    L     T  + +G   T+     L+   STTS +  +
Sbjct: 2440 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT-----LSPARSTTSGLVGE 2494

Query: 1011 NMLKNASRKPSDDKHFGQAPSKGTPSDGV--------SLSNLTQPSLTATDQQQQEEHYR 1062
            +     S   ++      +P+  + S+          S      P+ T +    +E    
Sbjct: 2495 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 2554

Query: 1063 IETRVSSSCLDLPDSTEEKGAPIETLGYHSA----------SNRRMSGEPIQTVESIRVP 1112
                 S+     PDST   G    +   HS+          ++   SG   ++  S   P
Sbjct: 2555 HSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP 2614

Query: 1113 GKGNR----------GHGREASRVGWFDLSTSGSSF-DNGPSSASELASLGGGGSGGLTG 1161
            G  +             G+E++       ST  + F D+  SS    AS     S G   
Sbjct: 2615 GSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 2674

Query: 1162 FKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPS----PLEHGTPFQREPVGPSSAPP 1217
               +P    +P  Q    +F+++   ST     PPS    P+E  T + R    P S P 
Sbjct: 2675 TTLSPASSTSPGLQGESTTFQTHP-ASTHTTPSPPSTATAPVEESTTYHR---SPGSTP- 2729

Query: 1218 VPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPG 1277
                           TH P+   ++  ++++ + H++P     + SG          P  
Sbjct: 2730 --------------TTHFPASSTTSGHSEKSTIFHSSP-----DASG--------TTPSS 2762

Query: 1278 EHSSSGGSG 1286
             HS++ G G
Sbjct: 2763 AHSTTSGRG 2771



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 166/752 (22%), Positives = 271/752 (36%), Gaps = 67/752 (8%)

Query: 393  AEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPA-LALPNLANV 451
            +E S    S P  PT  +S AS  T + V   +T    +P +T  + SPA    P L+  
Sbjct: 2324 SEASTTFYSSPRSPTTTLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 2382

Query: 452  DLAKISSILSSL-TSVMKNT------GVSPA---SRPSPGTPT--SPSNLTSGLKTPA-- 497
                 SS   S  T+V   T      G  P    SRP+    T  +  + TSGL   +  
Sbjct: 2383 STTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 2442

Query: 498  ----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPA 553
                PA+T +  P     + +     +  S+   T T  +PA    S L+   T + +  
Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSP 2502

Query: 554  SEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQ 613
            S   + +   SP   ++S        S   P    S   + +S  SE SSTS S+     
Sbjct: 2503 SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 2562

Query: 614  SPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIH 673
            +   P +T   P  S   T +H+ SP +  T+ T+  +S  +    +  +TS S      
Sbjct: 2563 TTAFPDST-TTPGLSRHSTTSHS-SPGS--TDTTLLPASTTTSGPSQESTTSHSSPGSTD 2618

Query: 674  NFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTP 733
              L  +PG S   L+    S+   S+P  +H + F    TS+ I  ++ +      +G+P
Sbjct: 2619 TAL--SPG-STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI--VEASTRVHSSTGSP 2673

Query: 734  TQDEMMDKPTSSSVDTMSLLSKIISPGSST---PSSTRSPPPGRDESYPRELSNSVSTYR 790
                     TS  +   S   +     + T   P ST + P     +Y R   ++ +T+ 
Sbjct: 2674 RTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2733

Query: 791  PFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLE 850
            P    + S + + S           ++    +  TS + +             + +    
Sbjct: 2734 PAS-STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 2792

Query: 851  KKP----AKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLD-------- 898
              P    A +   SS  S TT   P   +     +E     + P S  + +         
Sbjct: 2793 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2852

Query: 899  -SSENCDRLSSSPGLFGAF--------SVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQ 949
             S E+    SSSPG             SVRG EP +  S   S + + FT DS  + L++
Sbjct: 2853 LSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 2912

Query: 950  STTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEF 1009
             +T     P       P  +    L     T  + +G   T+     L+   STTS +  
Sbjct: 2913 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT-----LSPARSTTSGLVG 2967

Query: 1010 KNMLKNASRKPSDDKHFGQAPSKGTPSDGV--------SLSNLTQPSLTATDQQQQEEHY 1061
            ++     S   ++      +P+  + S+          S      P+ T +    +E   
Sbjct: 2968 ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 3027

Query: 1062 RIETRVSSSCLDLPDSTEEKGAPIETLGYHSA 1093
                  S+     PDST   G   E    HS+
Sbjct: 3028 SHSQPGSTHTTAFPDSTTTSGLSQEPTASHSS 3059



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 227/1057 (21%), Positives = 351/1057 (33%), Gaps = 160/1057 (15%)

Query: 393  AEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPA-LALPNLANV 451
            +E S    S P  PT  +S AS  T + V   +T    +P +T  + SPA    P L+  
Sbjct: 3881 SEASTTFYSSPRSPTTTLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 3939

Query: 452  DLAKISSI----------LSSLTSVMKNTGVSPASRPSPGTPT--SPSNLTSGLKTPA-- 497
                 SS            S+ TSV +    +  SRP+    T  +  + TSGL   +  
Sbjct: 3940 STTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 3999

Query: 498  ----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPA 553
                PA+T +  P     + +     +  S+   T T+ +PA    S L+   T + +  
Sbjct: 4000 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSP 4059

Query: 554  SEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQ 613
            S   + +   SP   ++S        S   P    S   + +S  SE SSTS S+     
Sbjct: 4060 SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 4119

Query: 614  SPGLPSTTFKLPSNSLGFTATHNTSPAAP-PTEVTICQSSEVSKPKLESESTSPSLEMKI 672
            +   P +T      + G +    TS ++   TE T+   S  +    +  +T  S     
Sbjct: 4120 TTAFPDST-----TTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT 4174

Query: 673  H-NFLKGNPGFSGL-NLNIPILSSLGS-----------SAPSESHPSDFQRGPTSTSIDN 719
                L  +   SGL   + P  SS GS           S   +   + FQ  P+S+    
Sbjct: 4175 ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSS---- 4230

Query: 720  IDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES-- 777
             D TP     +  P +         SS  T    +   + G S  S+T    PG   +  
Sbjct: 4231 -DTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTAL 4289

Query: 778  YPRELSNSV----STYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDY 833
            +P   + SV     T  P   GS      P  G    + L + S       T+F      
Sbjct: 4290 FPTRSATSVLVGEPTTSPISSGSTETTALP--GSTTTAGLSEKS-------TTF------ 4334

Query: 834  RDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSV 893
                YS P         + P  ++  +S  S     +   S+ SH        +AFP S 
Sbjct: 4335 ----YSSP---------RSPDTTLSPASTTSSGVSEE---STTSHSRPGSMHTTAFPSST 4378

Query: 894  RALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTG 953
              +   S+      SSPG        G+   S   P  +   S  +P S   +L    T 
Sbjct: 4379 -TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS--SPGSTETTLLPDNTT 4435

Query: 954  HLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTIST--------TS 1005
               L +   P       H S  SP  TL +P G     G      S  ++        T+
Sbjct: 4436 ASGLLEASTP------VHSSTGSPHTTL-SPAGSTTRQGESTTFQSWPNSKDTTPAPPTT 4488

Query: 1006 TIEFKNMLKNASRKPSD--DKHFGQA--------PSKGTPSDGVSLSNLTQPSLTATDQQ 1055
            T  F  +   +   PS     HF  +         S    S  V+ +    P+ + T   
Sbjct: 4489 TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL 4548

Query: 1056 QQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKG 1115
             +E      +  S+  +  P+S    G   E+   HS++   +S  P  T   +  P   
Sbjct: 4549 VEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 4608

Query: 1116 NRGHGREASRVGWFDLSTSGSSFDNGPSSASELAS--------------LGGGG----SG 1157
            +   G  A+       +TSG S ++  S +S+ A+              LG       S 
Sbjct: 4609 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 4668

Query: 1158 GLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPL----EHGTPFQREPVGPS 1213
            G       P     P   E   +F S+  ++   H    S      E  T     PV  +
Sbjct: 4669 GSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 4728

Query: 1214 SAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPP 1273
            + P                   P+   ++   +E+   H++    PG    + FP     
Sbjct: 4729 TTPS------------------PARSTTSGLVEESTAYHSS----PGSTQTMHFPESSTA 4766

Query: 1274 PPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKDHSSLLQ 1333
                E S +  S    +   PP      S        P + H   G++A      SS   
Sbjct: 4767 SGRSEESRTSHSSTTHTISSPP------STTSALVEEPTSYHSSPGSIATTHFPESSTTS 4820

Query: 1334 GTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLT 1370
            G   E       P D  G T    +     R+ ES T
Sbjct: 4821 GRSEESTASHSSP-DTNGITPLPAHFTTSGRIAESTT 4856



 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 214/957 (22%), Positives = 338/957 (35%), Gaps = 170/957 (17%)

Query: 394  EKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDL 453
            E+S  S S P      +S AS+ TP     + T     P +T  +  P     ++   + 
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP 2886

Query: 454  AKISSILSS-----LTSVMKNTGVSPASRPSPGTPTS-----PSNLTSG--------LKT 495
                S  +S      T     +G++  S   PG+P S     P+ LT+           +
Sbjct: 2887 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 2946

Query: 496  PAPATTTSHNPLANILSKV--EITPESILSALSKTQT-QSAPALQGLSSLLQSVTGNPVP 552
             + +T T+ +P  +  S +  E TP  +  + ++T T   +P    LS   +S T    P
Sbjct: 2947 SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE--KSTTFYTSP 3004

Query: 553  ASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVS-STSASKASI 611
             S  A+     SPA TT S +   +  S +QP    +  +  +++TS +S   +AS +S 
Sbjct: 3005 RSPDAT----LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQ 3060

Query: 612  GQ-----SPGLPSTTFKLPSNSLG-FTATHNTSPAAPPTEVTICQSSEVSKPKLESESTS 665
            G      SPG  STT    ++SLG  + T ++SP    TE T+     ++   +E+ + +
Sbjct: 3061 GSTEATLSPG--STT----ASSLGQQSTTFHSSPG--DTETTLLPDDTITSGLVEASTPT 3112

Query: 666  PSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPV 725
             S    +H  L   P  S             +SA  +   + FQ  P+S+     D TP 
Sbjct: 3113 HSSTGSLHTTL--TPASS-------------TSAGLQEESTTFQSWPSSS-----DTTPS 3152

Query: 726  RDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES--YPRELS 783
                +  P +         SS  T    +   + G S  S+T    PG   +  +P   +
Sbjct: 3153 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 3212

Query: 784  NSV----STYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYS 839
             SV     T  P   GS      P  G    + L + S       T+F          YS
Sbjct: 3213 TSVLVGEPTTSPISSGSTETTALP--GSTTTAGLSEKS-------TTF----------YS 3253

Query: 840  GPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDS 899
             P         + P  ++  +S  S     +   S+ SH        +AFP S   +   
Sbjct: 3254 SP---------RSPDTTLSPASTTSSGVSEE---STTSHSRPGSTHTTAFPGST-TMPGV 3300

Query: 900  SENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQ 959
            S+      SSPG        G+   S   P  +   S   P S   +L    T    L +
Sbjct: 3301 SQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS--GPGSTETTLLPDNTTASGLLE 3358

Query: 960  KQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTIST--------TSTIEFKN 1011
               P       H S  SP  TL +P G     G      S  ++        T+T  F  
Sbjct: 3359 ASTP------VHSSTGSPHTTL-SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVE 3411

Query: 1012 MLKNASRKPSD--DKHFGQA--------PSKGTPSDGVSLSNLTQPSLTATDQQQQEEHY 1061
            +   +   PS     HF  +         S    S  V+ +    P+ + T    +E   
Sbjct: 3412 LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTT 3471

Query: 1062 RIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGR 1121
               +  S+  +  P+S    G   E+   HS++   +S  P  T   +  P   +   G 
Sbjct: 3472 YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 3531

Query: 1122 EASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQF--QESVG 1179
             A+       +TSG S ++  S +S+ A          TG    P +        + +  
Sbjct: 3532 TATTHFPDSSTTSGRSEESTASHSSQDA----------TGTIVLPARSTTSVLLGESTTS 3581

Query: 1180 SFRSNSFNSTFEHHLP-----PSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTH 1234
               S S  +T    LP     P   E  T F   P  P                  A T 
Sbjct: 3582 PISSGSMETT---ALPGSTTTPGLSEKSTTFHSSPRSP------------------ATTL 3620

Query: 1235 LPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFST 1291
             P+   S+  ++E+  +H+     PG      FP     P    HS++  S  P ST
Sbjct: 3621 SPASTTSSGVSEESTTSHSR----PGSTHTTAFPDSTTTPGLSRHSTTSHSS-PGST 3672



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 176/812 (21%), Positives = 292/812 (35%), Gaps = 67/812 (8%)

Query: 319  SPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEP-VTDNRDVEDMELSDVE 377
            +PV S S  +P  T S +      GE +   +  + K  TP P  T +  VE    S   
Sbjct: 3361 TPVHS-STGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGS 3419

Query: 378  DDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSL 437
               +             +S  ST+V + P      A++ TP P   T +  + +      
Sbjct: 3420 PSSTPTTHFSASSTTLGRSEESTTVHSSPV-----ATATTPSPARSTTSGLVEESTTYHS 3474

Query: 438  SPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPA 497
            SP     + +    D    S      T+   +T  + +S PS  T       TS   +P 
Sbjct: 3475 SPGSTQTM-HFPESDTT--SGRGEESTTSHSSTTHTISSAPST-TSALVEEPTSYHSSPG 3530

Query: 498  PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAA 557
             +T T+H P ++  S       +  S+   T T   PA    S LL   T +P+    + 
Sbjct: 3531 -STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI---SSG 3586

Query: 558  SQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTS----EVSSTSASKASIGQ 613
            S  T+A P +TT   +  ++    + P  P +   SP S+TS    E S+TS S+     
Sbjct: 3587 SMETTALPGSTTTPGLSEKSTTFHSSPRSPAT-TLSPASTTSSGVSEESTTSHSRPGSTH 3645

Query: 614  SPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIH 673
            +   P +T   P  S   T +H +SP +  T+ T+  +S  +    +  +TS S      
Sbjct: 3646 TTAFPDST-TTPGLSRHSTTSH-SSPGS--TDTTLLPASTTTSGSSQESTTSHSSSGSTD 3701

Query: 674  NFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTP 733
              L  +PG S   L+    S+   S+P  +H + F    TS+ I  ++ +      +G+P
Sbjct: 3702 TAL--SPG-STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI--VEASTRVHSSTGSP 3756

Query: 734  TQDEMMDKPTSSSVDTMSLLSKIISPGSST---PSSTRSPPPGRDESYPRELSNSVSTYR 790
                     TS  +   S   +     + T   P ST + P     +Y R   ++ +T+ 
Sbjct: 3757 RTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 3816

Query: 791  PFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLE 850
            P    + S + + S           ++    +  TS + +             + +    
Sbjct: 3817 P-ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 3875

Query: 851  KKP----AKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLD-------- 898
              P    A +   SS  S TT   P   +     +E     + P S  + +         
Sbjct: 3876 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 3935

Query: 899  -SSENCDRLSSSPG--------LFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQ 949
             S E+    SSSPG             SVR  EP +  S   S + + FT DS  + L++
Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995

Query: 950  STTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEF 1009
             +T     P       P  +    L     T  + +G   T      L+   STTS +  
Sbjct: 3996 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK-----LSPARSTTSGLVG 4050

Query: 1010 KNMLKNASRKPSDDKHFGQAPSKGTPSDGV--------SLSNLTQPSLTATDQQQQEEHY 1061
            ++     S   ++      +P+  + S+          S      P+ T +    +E   
Sbjct: 4051 ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 4110

Query: 1062 RIETRVSSSCLDLPDSTEEKGAPIETLGYHSA 1093
                  S+     PDST   G   E    HS+
Sbjct: 4111 SHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSS 4142



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 215/962 (22%), Positives = 329/962 (34%), Gaps = 150/962 (15%)

Query: 393  AEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPA-LALPNLANV 451
            +E S    S P  PT  +S AS  T + V   +T    +P +T  + SPA    P L+  
Sbjct: 1241 SEASTTFYSSPRSPTTTLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 1299

Query: 452  DLAKISSIL----------SSLTSVMKNTGVSPASRPSPGTPT--SPSNLTSGLKTPA-- 497
                 SS            S+ TSV      +  SRP+    T  +  + TSGL   +  
Sbjct: 1300 STTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 1359

Query: 498  ----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPA 553
                PA+T +  P     + +     +  S+   T T+ +PA    S L+   T + +  
Sbjct: 1360 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSP 1419

Query: 554  SEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQ 613
            S   + +   SP   ++S        S   P    S   + +S  SE SSTS S+     
Sbjct: 1420 SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 1479

Query: 614  SPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIH 673
            +   P +T      S   T +H++  +   TE T+   S  +    +  +T  S      
Sbjct: 1480 TTAFPDST-TTSDLSQEPTTSHSSQGS---TEATLSPGSTTASSLGQQSTTFHSSPGDTE 1535

Query: 674  -NFLKGNPGFSGL-NLNIPILSSLGS-----------SAPSESHPSDFQRGPTSTSIDNI 720
               L  +   SGL   + P  SS GS           SA  +   + FQ  P+S+     
Sbjct: 1536 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS----- 1590

Query: 721  DGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES--Y 778
            D TP     +  P +         SS  T    +   + G S  S+T    PG   +  +
Sbjct: 1591 DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALF 1650

Query: 779  PRELSNSV----STYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYR 834
            P   + SV     T  P   GS      P  G    + L + S       T+F       
Sbjct: 1651 PTRSATSVLVGEPTTSPISSGSTETTALP--GSTTTAGLSEKS-------TTF------- 1694

Query: 835  DFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVR 894
               YS P         + P  ++  +S  S     +   S+ SH        +AFP S  
Sbjct: 1695 ---YSSP---------RSPDTTLSPASTTSSGVSEE---STTSHSRPGSTHTTAFPGST- 1738

Query: 895  ALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGH 954
             +   S+      SSPG        G+   S   P  +   S  +P S   +L    T  
Sbjct: 1739 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS--SPGSTETTLLPDNTTA 1796

Query: 955  LSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTIST--------TST 1006
              L +   P       H S  SP  TL +P G     G      S  S+        T+T
Sbjct: 1797 SGLLEASTP------VHSSTGSPHTTL-SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTT 1849

Query: 1007 IEFKNMLKNASRKPSD--DKHFGQA--------PSKGTPSDGVSLSNLTQPSLTATDQQQ 1056
              F  +   +   PS     HF  +         S    S  V+ +    P+ + T    
Sbjct: 1850 SAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 1909

Query: 1057 QEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGN 1116
            +E      +  S+  +  P+S+   G   E+   HS++   +S  P  T   +  P   +
Sbjct: 1910 EESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH 1969

Query: 1117 RGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQF-- 1174
               G  A+       +TSG S ++  S +S+ A          TG    P +        
Sbjct: 1970 SSPGSTATTHFPDSSTTSGRSEESTASHSSQDA----------TGTIVLPARSTTSVLLG 2019

Query: 1175 QESVGSFRSNSFNSTFEHHLP-----PSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSR 1229
            + +     S S  +T    LP     P   E  T F   P  P                 
Sbjct: 2020 ESTTSPISSGSMETT---ALPGSTTTPGLSEKSTTFHSSPRSP----------------- 2059

Query: 1230 DAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPF 1289
             A T  P+   S+  ++E+  +H+     PG      FP     P    HS++  S  P 
Sbjct: 2060 -ATTLSPASTTSSGVSEESTTSHSR----PGSTHTTAFPDSTTTPGLSRHSTTSHSS-PG 2113

Query: 1290 ST 1291
            ST
Sbjct: 2114 ST 2115



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 245/1083 (22%), Positives = 379/1083 (34%), Gaps = 230/1083 (21%)

Query: 315  DPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELS 374
            +P+ SP+ S SM+  +  GS +      G   +S T  S   +            D  LS
Sbjct: 251  EPKTSPITSASMETTALPGSTT----TAGLSEKSTTFYSSPRS-----------PDRTLS 295

Query: 375  DVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTM--TATPPLPKP 432
                  S +         +EKS  S S P  PT  I+   S T   V+   TA+  +P  
Sbjct: 296  PARTTSSGV---------SEKSTTSHSRP-GPTHTIAFPDSTTMPGVSQESTASHSIPGS 345

Query: 433  VNTSLSP---SPALALPNLANV-------------DLAKISSILSSLTSVMKNTG----- 471
             +T+LSP   +P+   P                  D    S +L + T V  +TG     
Sbjct: 346  TDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTT 405

Query: 472  VSPASRPS-PGTPTSPSNLTSGLKT-PAPATTTSHNPLANILSKVEITPESILSALSKTQ 529
            +SP+S  +  G PT+  +  S   T PAP+ TTS         K+  T  S  S+   T 
Sbjct: 406  LSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTS------AFVKLSTTYHSSPSSTPTTH 459

Query: 530  TQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKS 589
              ++    G S     V  +PV  +     + SA+  +   ST   R+  S+     P+S
Sbjct: 460  FSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPES 519

Query: 590  FNYSPNSSTSEV--SSTSASKASIGQSPGLPSTTFKLP----SNSLGFTAT--------- 634
               S +S  S     ST+ +K+S       PSTT  L      +SLG T T         
Sbjct: 520  STTSGHSEESATFHGSTTHTKSS------TPSTTAALAHTSYHSSLGSTETTHFRDSSTI 573

Query: 635  ---------HNTSPAAPPTEVTICQS-----------SEVSKPKLES-----ESTSPSLE 669
                      ++SP A  T V    S           S +S   +E+      +T P L 
Sbjct: 574  SGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLS 633

Query: 670  MKIHNFLKGNPGFSGLNLNIPILSS-------LGSSAPSESHPSDFQRGPTSTSIDNIDG 722
             K   F          +L   + SS          S P  +H + F   P ST++  +  
Sbjct: 634  EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAF---PGSTTMPGLSQ 690

Query: 723  TPVRDERSGTPTQDEMMDKPTSS---------------SVDTMSLLSKIISPG---SSTP 764
                   S  PT   +    T++               S +T  L     + G   +S P
Sbjct: 691  ESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMP 750

Query: 765  --SSTRSP-----PPG----RDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSL 813
              SSTRSP     P G    + ES       S    RP    + S + +PS       S 
Sbjct: 751  VHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSS 810

Query: 814  MDSSQEKFYPDTS--FQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQP 871
            + ++       TS   +E   Y    +S P  +  M+  +            SDTT  + 
Sbjct: 811  IPTTHISARSTTSGLVEESTTY----HSSPGSTQTMHFPE------------SDTTSGRG 854

Query: 872  ILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSP 931
              S+ SH +    + SA P +  AL++   +     SSPG         +   S RS   
Sbjct: 855  EESTTSHSSTTHTISSA-PSTTSALVEEPTS---YHSSPGSTATTHFPDSSTTSGRSEES 910

Query: 932  SKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTS 991
            + + S           SQ  TG + LP +               +    L   T  P +S
Sbjct: 911  TASHS-----------SQDATGTIVLPARS--------------TTSVLLGESTTSPISS 945

Query: 992  GVEKVLASTISTTS--TIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSL 1049
            G  +  A   STT+    E      ++ R P+         S G   +  S ++ ++P  
Sbjct: 946  GSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEE--STTSRSRPGS 1003

Query: 1050 TATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESI 1109
            T T            +R S++    P ST+    P  T     +     S     + ++ 
Sbjct: 1004 THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTA 1063

Query: 1110 RVPGKGNR-GHGREASRVGWFDLSTSGSSF-DNGPSSASELASLGGGGSGGLTGFKTAPY 1167
              PG       G+E++       ST  + F D+  SS    AS     S G      +P 
Sbjct: 1064 LSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 1123

Query: 1168 KERAPQFQESVGSFRSNSFNSTFEHHLPPS----PLEHGTPFQREPVGPSSAPPVPPKDH 1223
               +P  Q    +F+++   ST     PPS    P+E  T + R    P S P       
Sbjct: 1124 SSTSPGLQGESTAFQTHP-ASTHTTPSPPSTATAPVEESTTYHR---SPGSTP------- 1172

Query: 1224 GGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSG 1283
                     TH P+   ++  ++++ + H++P     + SG          P   HS++ 
Sbjct: 1173 --------TTHFPASSTTSGHSEKSTIFHSSP-----DASG--------TTPSSAHSTTS 1211

Query: 1284 GSG 1286
            G G
Sbjct: 1212 GRG 1214



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 238/1050 (22%), Positives = 369/1050 (35%), Gaps = 173/1050 (16%)

Query: 311  STLPDPEESPVPSPSMDAPSPTG-----------SESPFQGMGGEESQSPTMESEKSATP 359
            ST      S +P+  + A S T            S    Q M   ES + +   E+S T 
Sbjct: 801  STTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS 860

Query: 360  EPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPV 419
               T +       +S      S ++ E      +  S  +T  P   T +     S    
Sbjct: 861  HSSTTHT------ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES---- 910

Query: 420  PVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPS 479
                TA+       ++S   +  + LP  +   +    S  S ++S    T   P S  +
Sbjct: 911  ----TAS-------HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 959

Query: 480  PGTPTSPSNLTSGLKTPA----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPA 535
            PG     +   S  ++PA    PA+TTS       +S+   T  S   +   T    +  
Sbjct: 960  PGLSERSTTFHSSPRSPATTLSPASTTSSG-----VSEESTTSRSRPGSTHTTAFPDSTT 1014

Query: 536  LQGLS---------------SLLQSVTGNPVPASE-------AASQSTSASPANTTV--- 570
              GLS               +LL + T    P+ E       + S  T+ SP +TT    
Sbjct: 1015 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSF 1074

Query: 571  ---STIKGRNLPSSAQPFIPKSFNYS--PNSSTSEVSSTSASKASI----GQSPGL--PS 619
               ST    N  S+     P S   S    +ST   SST + + ++      SPGL   S
Sbjct: 1075 GQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 1134

Query: 620  TTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE-SESTSPSLEMKIHNFLKG 678
            T F+    S   T +  ++  AP  E T    S  S P      S++ S   +       
Sbjct: 1135 TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 1194

Query: 679  NPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDG---TPVRDERSGT--- 732
            +P  SG        SS  S+       +  +  P ST I  + G   TP   E S T   
Sbjct: 1195 SPDASGTT-----PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 1249

Query: 733  ----PTQDEMMDKPTSSSVDTMSLLSKIISPGS--STPSSTRSPPPGRDES----YPREL 782
                PT        TS  V   S  S+   PGS  ST S   +  PG  E     Y    
Sbjct: 1250 SPRSPTTTLSPASMTSLGVGEESTTSR-SQPGSTHSTVSPASTTTPGLSEESTTVYSSSR 1308

Query: 783  SNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPP 842
             ++ +T  P    +    ++P+    RP+    S+    + + S           + G P
Sbjct: 1309 GSTETTVFPHSTTTSVHGEEPTTFHSRPA----STHTTLFTEDSTTSGLTEESTAFPGSP 1364

Query: 843  PSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSEN 902
             S    L      + L ++ L + +   P  S  +      G K +   S  + L     
Sbjct: 1365 ASTQTGL-----PATLTTADLGEESTTFPSSSGST------GTKLSPARSTTSGLVGEST 1413

Query: 903  CDRLSSSPGLFGAFSVRGNEPGSDRSPSPS-KNDSFFT-PDSNHNSLSQSTTGHLSLPQK 960
              RLS S       +     PGS  +PS S K+ +F+T P S   +LS +TT    + ++
Sbjct: 1414 PSRLSPSS------TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 1467

Query: 961  QYPDSPHPVPHRSLFSPQNTLAAPTGHPPTS------GVEKVLASTISTTSTIEFKNMLK 1014
                   P    +   P +T  +     PT+        E  L+   +T S++  ++   
Sbjct: 1468 SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 1527

Query: 1015 NASRKPS------DDKHFGQAPSKGTP---SDGVSLSNLTQPSLTATDQQQQEEHYRIET 1065
            ++S   +      DD          TP   S G   + LT  S T+   Q++   ++   
Sbjct: 1528 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP 1587

Query: 1066 RVSSSCLDLPDSTEEKGAPIE-TLGYHS------------ASNRRMSGEPIQTVESIRVP 1112
              S +    P +T    AP+E +  YHS            +S      E   TV S   P
Sbjct: 1588 SSSDTTPSPPGTT---AAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS--SP 1642

Query: 1113 GKGNRG--HGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKER 1170
            G         R A+ V   + +TS  S  +  ++A   ++   G S   T F ++P   R
Sbjct: 1643 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSP---R 1699

Query: 1171 APQFQESVGSFRSN--SFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPK---DHGG 1225
            +P    S  S  S+  S  ST  H  P S   H T F     G ++ P V  +    H  
Sbjct: 1700 SPDTTLSPASTTSSGVSEESTTSHSRPGS--THTTAFP----GSTTMPGVSQESTASHSS 1753

Query: 1226 IFSRDAPTHLPSVDLSNPFTKEAALAHAAP 1255
              S D  T  P    ++    E+   H++P
Sbjct: 1754 PGSTDT-TLSPGSTTASSLGPESTTFHSSP 1782



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 200/954 (20%), Positives = 331/954 (34%), Gaps = 137/954 (14%)

Query: 331  PTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDG-SKIIVEDRK 389
            PT S S  QG   E + SP   +  S   +  T +    D E + + DD  +  +VE   
Sbjct: 3053 PTASHSS-QG-STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST 3110

Query: 390  EKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLA 449
               +   ++ T++    + +       T      +++   P P  T+ +P          
Sbjct: 3111 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP---------- 3160

Query: 450  NVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLAN 509
                 ++S+   S  S    T  S +S     T    S  ++ + +   AT T+  P  +
Sbjct: 3161 ----VEVSTTYHSRPSSTPTTHFSASS-----TTLGRSEESTTVHSSPGATGTALFPTRS 3211

Query: 510  ILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTT 569
              S +   P +   +   T+T + P     + L +  T      S   S  T+ SPA+TT
Sbjct: 3212 ATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKST---TFYSSPRSPDTTLSPASTT 3268

Query: 570  VSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSL 629
             S +   +  S ++P    +  +  +++   VS  S +  S   SPG   TT    S + 
Sbjct: 3269 SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHS---SPGSTDTTLSPGSTTA 3325

Query: 630  GFTATHNTSPAAPP--TEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNL 687
                  +T+  + P  TE T+   +  +   LE+ +   S     H  L           
Sbjct: 3326 SSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL----------- 3374

Query: 688  NIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSV 747
                  S   S   +   + FQ  P S      D TP     +    +       + SS 
Sbjct: 3375 ------SPAGSTTRQGESTTFQSWPNSK-----DTTPAPPTTTSAFVELSTTSHGSPSST 3423

Query: 748  DTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGM 807
             T    +   + G S  S+T    P    + P    ++ S     GL  ES     S G 
Sbjct: 3424 PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS-----GLVEESTTYHSSPG- 3477

Query: 808  ERPSSLMDSSQEKFYP--DTSFQEDEDYRDFEYS-----GPPPSAMMNLEKKPAKSILKS 860
                    S+Q   +P  DT+    E+      S        PS    L ++P      S
Sbjct: 3478 --------STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS--YHS 3527

Query: 861  SKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALL-----DSSENCDRLSSSPGLFGA 915
            S  S  T + P  S+ S R++E     +   +   ++      +S      ++SP   G+
Sbjct: 3528 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 3587

Query: 916  FSVRGNEPGSDRSPSPSKNDSFF--TPDSNHNSLSQSTTGHLSLPQKQYPDSPHP-VPHR 972
                   PGS  +P  S+  + F  +P S   +LS ++T    + ++       P   H 
Sbjct: 3588 METTA-LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHT 3646

Query: 973  SLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSK 1032
            + F    T    + H  TS      +S  ST +T+   +   + S + S   H       
Sbjct: 3647 TAFPDSTTTPGLSRHSTTSH-----SSPGSTDTTLLPASTTTSGSSQESTTSH------- 3694

Query: 1033 GTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHS 1092
               S G + + L+  S TA    Q+   +      + + L  PDST   G    +   HS
Sbjct: 3695 --SSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL-FPDSTTSSGIVEASTRVHS 3751

Query: 1093 ASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLG 1152
            +     +G P  T+        G +G                 ++F   P+S     S  
Sbjct: 3752 S-----TGSPRTTLSPASSTSPGLQG---------------ESTAFQTHPASTHTTPS-- 3789

Query: 1153 GGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSF--NSTFEHHLPPSPLEHGTPFQREPV 1210
                       TAP +E +  +  S GS  +  F  +ST   H   S + H +P      
Sbjct: 3790 ------PPSTATAPVEE-STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP-DASGT 3841

Query: 1211 GPSSAPPVPPKDHGGIFSRDAP-----THLPSVDLSNPFTKEAALAHAAPPPPP 1259
             PSSA            SR +P     T LP    + P   EA+    + P  P
Sbjct: 3842 TPSSAHSTTSGRGESTTSRISPGSTEITTLPG-STTTPGLSEASTTFYSSPRSP 3894



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 198/949 (20%), Positives = 322/949 (33%), Gaps = 176/949 (18%)

Query: 464  TSVMKNTGVSPASRPSPGTP-TSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESIL 522
            TS+  NT  + AS PS   P T+ S+    +     +T T H   ++  S          
Sbjct: 171  TSIGGNT--TSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSH 228

Query: 523  SALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSA 582
            S    T T   P+    S  +     +P+ +   AS  T+A P +TT + +  ++    +
Sbjct: 229  SGPGATGTTLFPSHSATSVFVGEPKTSPITS---ASMETTALPGSTTTAGLSEKSTTFYS 285

Query: 583  QPFIPKSFNYSP----NSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTS 638
             P  P     SP    +S  SE S+TS S+     +   P +T  +P  S   TA+H+  
Sbjct: 286  SPRSPDR-TLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDST-TMPGVSQESTASHSI- 342

Query: 639  PAAPPTEVTICQSSEVSKPKLESEST----SPSLEMKIHNFLKGNPGFSGL-NLNIPILS 693
               P +  T       +   L  EST    SP         L  N   SGL   + P+ S
Sbjct: 343  ---PGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR--LPDNTTTSGLLEASTPVHS 397

Query: 694  SLGS---------SAPSESHPSDFQRGPTSTSIDNI-DGTPVRDERSGTPTQDEMMDKPT 743
            S GS         S   E  P+ FQ  P+S        GT     +  T         PT
Sbjct: 398  STGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPT 457

Query: 744  S--SSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYK 801
            +  S+  T    S+  +P  S+P +T + PP    +    +  S + +R  G        
Sbjct: 458  THFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPG-------- 509

Query: 802  QPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPP-------PSAMMNLEKKPA 854
                          S+Q   +P++S           + G         PS    L     
Sbjct: 510  --------------STQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSY 555

Query: 855  KSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRL---SSSPG 911
             S L S+   +TT ++   S+ S R++E     + P ++   +  + +   +    S+P 
Sbjct: 556  HSSLGST---ETTHFRDS-STISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPS 611

Query: 912  LFGAFSVRGNE-PGSDRSPSPSKNDSFF-----TPDSNHNSLS--------QSTTGHL-- 955
               + S+     PGS   P  S+  + F     +PD+ H   S        +STT H   
Sbjct: 612  PISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRP 671

Query: 956  ---------------SLPQKQYPDSPHPVPHRSLFSPQNTLAAPTG-------HPPTSGV 993
                            L Q+       P P  +  SP +T A+  G         P S  
Sbjct: 672  GSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTE 731

Query: 994  EKVLASTISTTSTIEFKNMLKNASRKP---------------SDDKHFGQAPSKGTPSDG 1038
              +L    + +  +E    + +++R P               S   H   +     P+  
Sbjct: 732  TTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPP 791

Query: 1039 VSLSNLTQPSLTATDQQQQEEHYRIETRVSSS-----------------CLDLPDSTEEK 1081
             + S   +PS T+           I  R ++S                  +  P+S    
Sbjct: 792  TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 851

Query: 1082 GAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNG 1141
            G   E+   HS++   +S  P  T   +  P   +   G  A+       +TSG S ++ 
Sbjct: 852  GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 911

Query: 1142 PSSASELASLGGGGSGGLTGFKTAPYKERAPQF--QESVGSFRSNSFNSTFEHHLP---- 1195
             S +S+ A          TG    P +        + +     S S  +T    LP    
Sbjct: 912  ASHSSQDA----------TGTIVLPARSTTSVLLGESTTSPISSGSMETT---ALPGSTT 958

Query: 1196 -PSPLEHGTPFQREPVGPSSAPPVPPKDHGGIF-------SRDAPTH---LPSVDLSNPF 1244
             P   E  T F   P  P++          G+        SR   TH    P    +   
Sbjct: 959  TPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 1018

Query: 1245 TKEAALAHAAPPPPPGEHSGIPFPTP---PPPPPPGEHSSSGGSGVPFS 1290
            ++ +  +H++P     + + +P  T    P       HSSSG +    S
Sbjct: 1019 SRHSTTSHSSPGST--DTTLLPASTTTSGPSQESTTSHSSSGSTDTALS 1065



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 89/371 (23%), Positives = 144/371 (38%), Gaps = 26/371 (7%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVED 370
            +T P P  S       ++ +   S    Q M   ES + +  SE+S T    T +     
Sbjct: 4728 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT---- 4783

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVP-TKPTENISKASSCTPVPVTMTATPPL 429
              +S      S ++ E      +  S  +T  P +  T   S+ S+ +          PL
Sbjct: 4784 --ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPL 4841

Query: 430  PKPVNTS--LSPSPALAL-PNLANVDLAKISSI--LSSLTSVMKNTGVSPASRPSPGTPT 484
            P    TS  ++ S    + P      LA  ++   LS+ ++++ ++  SP    SP + T
Sbjct: 4842 PAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMT 4901

Query: 485  SPS--NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSL 542
            S S     + L + A +T T+  P +   S +     +  S    T+T  +P     SS 
Sbjct: 4902 SSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSF 4961

Query: 543  LQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVS 602
             Q  T    P S+  S  ++ SPA+TTV    G +  S+     P S   +  S ++ +S
Sbjct: 4962 AQEFT---TPHSQPGSALSTVSPASTTV---PGLSEESTTFYSSPGSTETTAFSHSNTMS 5015

Query: 603  STSASKASIGQSPGLPSTTF--KLPSNSLG--FTATHNTSPA--APPTEVTICQSSEVSK 656
              S        SPG   T     L +  +G   TA H++S A    P       S  V +
Sbjct: 5016 IHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGE 5075

Query: 657  PKLESESTSPS 667
            P     S SP+
Sbjct: 5076 PTTFYISPSPT 5086



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 137/650 (21%), Positives = 219/650 (33%), Gaps = 78/650 (12%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVED 370
            +T P P  S       ++ +   S    Q M   ES + +   E+S T    T +     
Sbjct: 4535 ATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHT---- 4590

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
              +S      S ++ E      +  S  +T  P   T +     S        TA+    
Sbjct: 4591 --ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES--------TAS---- 4636

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLT 490
               ++S   +  + LP  +   +    S  S ++S    T   P S  +PG     +   
Sbjct: 4637 ---HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH 4693

Query: 491  SGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP 550
            S   +P+   TT  +  +  L + E +  ++ S+   T T  +PA    S L++  T   
Sbjct: 4694 S---SPSSTPTTHFSASSTTLGRSEEST-TVHSSPVATATTPSPARSTTSGLVEESTAYH 4749

Query: 551  VPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKAS 610
               S   S  T   P ++T S   GR+  S            SP S+TS +     S  S
Sbjct: 4750 ---SSPGSTQTMHFPESSTAS---GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS 4803

Query: 611  IGQSPGLPSTT-FKLPSNSLGFTATHNTSPAAPPTE-VTICQSSEVSKPKLESESTSPSL 668
               SPG  +TT F   S + G +     S ++P T  +T   +   +  ++   +T    
Sbjct: 4804 ---SPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYIS 4860

Query: 669  EMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDE 728
               +   L       GL+    IL S   S      P+      TS+SI           
Sbjct: 4861 PGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM----TSSSI----------- 4905

Query: 729  RSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVST 788
             SG PT         + S  T +  +   + G S  S+T    PG  E+    LS    T
Sbjct: 4906 -SGEPTSLYSQ----AESTHTTAFPASTTTSGLSQESTTFHSKPGSTET---TLSPGSIT 4957

Query: 789  YRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMN 848
               F     +P+ QP   +   S    +        T+F          YS P  +    
Sbjct: 4958 TSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTF----------YSSPGSTETTA 5007

Query: 849  LEKKPAKSI--LKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRL 906
                   SI   +S+   D+  +   +   +    + G +S           SS +    
Sbjct: 5008 FSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQEST-------AFHSSSDATGT 5060

Query: 907  SSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLS 956
            +  P    A  + G       SPSP+    F    S      +STT H S
Sbjct: 5061 TPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTS 5110



 Score = 31.6 bits (70), Expect = 5.9
 Identities = 45/198 (22%), Positives = 68/198 (34%), Gaps = 27/198 (13%)

Query: 392  PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANV 451
            PA  +       +    + S A+  TP+P   TA+  + +P    +SPSP          
Sbjct: 5036 PATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTY-------T 5088

Query: 452  DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGL----------KTPAPATT 501
             L   SS  S LT        SP+   +  +  S   L  GL          +   P   
Sbjct: 5089 TLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQGY 5148

Query: 502  TSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQST 561
              +  L+ + S    TPE + + L  T          +    ++ T     AS    Q+ 
Sbjct: 5149 VGYQCLSPLESFPVETPEKLNATLGMT----------VKVTYRNFTEKMNDASSQEYQNF 5198

Query: 562  SASPANTTVSTIKGRNLP 579
            S    N     +KG NLP
Sbjct: 5199 STLFKNRMDVVLKGDNLP 5216


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 238/1086 (21%), Positives = 392/1086 (36%), Gaps = 201/1086 (18%)

Query: 324  PSMDAPSPTGSESPFQGMGGE-----ESQSPTMESEKSATPEPVTDNRDVEDMELSDVED 378
            PS+   +P+G  +P   M         S++ T+ +  +AT  PV  + +      S    
Sbjct: 263  PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASS---SPTTA 319

Query: 379  DGSKIIVEDRKE-------KPAEKSAVSTS-------VPTKPTENISKASSCTPVPVTMT 424
            +G+ I      E        PA    V+TS        P   +  ++ ++  + +P T  
Sbjct: 320  EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAE 379

Query: 425  ATPPLPK------------PVNTSLSPSPALALPNLANVD---LAKISSILSSLTSVMKN 469
            AT  L              PV+T L  S   +  +   VD       +S  SS  +  ++
Sbjct: 380  ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAED 439

Query: 470  TGVSPASRPSPG-----------TPTSPSNLTSGLKTPAPATT--------TSHNPLANI 510
            T ++  S PS G           TP + S  ++   TP  + T        +S  P A +
Sbjct: 440  TSIA-TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEV 498

Query: 511  LSKVEITPESILSALSKTQTQSAPALQGLSSLLQSV---TGNPVP-ASEAASQSTSASPA 566
             S    TP    + L+     + P     +S L +    T  PV  +SEA+S ST+    
Sbjct: 499  NSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGT 558

Query: 567  NTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTS----------EVSSTSASKASIGQSPG 616
            +   ST    + P +  P   +    S  S+TS            SS ++S ++  +   
Sbjct: 559  SIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTS 618

Query: 617  LPSTTFK-----LPSNSLGFT-------ATHNTSPAAPPTEVTICQSSEVSKPKLESEST 664
            +P++T+      + S S+  T       +T +T+P    T VT   S+E +     +E T
Sbjct: 619  MPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT--TSTEATSSSTTAEGT 676

Query: 665  SPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTP 724
            S    M    + +G+   + + +N  +++S  +S  S            +T +D      
Sbjct: 677  S----MPTSTYTEGSTPLTSMPVNTTLVASSEASTLS------------TTPVDTSTPVT 720

Query: 725  VRDERSGTPTQDEMMDKPTSS-SVDTMSLLSKIISPG--SSTPSSTRSPPPGRDESYPRE 781
               E S +PT  +    PTS+ S  +  L S  +S    +S+ +ST S  P  D S    
Sbjct: 721  TSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP-LDTSTHIT 779

Query: 782  LSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGP 841
             S   S       G+  P   PS+G    S L+ S      P TS               
Sbjct: 780  TSTEASCSPTTTEGTSMPISTPSEG----SPLLTSIPVSITPVTS--------------- 820

Query: 842  PPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSE 901
             P A   L   P  S   +S ++ +TE    +SS    A+   + ++     R  L S  
Sbjct: 821  -PEA-STLSTTPVDS---NSPVTTSTE----VSSSPTPAEGTSMPTSTYSEGRTPLTSMP 871

Query: 902  NCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTP-DSNHNSLSQSTTGHLSLPQK 960
                +S++     A S     P    +P  +  ++  +P  S   S+  ST G  S P  
Sbjct: 872  ----VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLT 927

Query: 961  QYPDSPHPVPHRSLFSPQNTLAA---PTGHPPTSGVEKVLASTISTTSTIEFKNMLKNAS 1017
              PDS  PV    + S   TL+A    T  P T+  E   + T +  ++I          
Sbjct: 928  SMPDSTTPV----VSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSI---------- 973

Query: 1018 RKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSS-----SCL 1072
              P+     G  P   TP     ++N ++ S  +T            T  SS        
Sbjct: 974  --PTSTPSEGTTPLTSTPVSHTLVAN-SEASTLSTTPVDSNTPLTTSTEASSPPPTAEGT 1030

Query: 1073 DLPDSTEEKGA------PIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRV 1126
             +P ST  +G+      P+ T    S+    +S  P  T   +    + +      ++  
Sbjct: 1031 SMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQAS----SSSTTA 1086

Query: 1127 GWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSF 1186
                + TS  S  + P ++  +++     S   T   T P     P    +  S    + 
Sbjct: 1087 DGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAST-LSTTPVDTSIPVTTSTEASSSPTTA 1145

Query: 1187 NSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTK 1246
              T     PPS  E  TP    PV  +            + S +A T L +  + +  T+
Sbjct: 1146 EGTSIPTSPPS--EGTTPLASMPVSTTL-----------VVSSEANT-LSTTPVDSK-TQ 1190

Query: 1247 EAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVP 1306
             A    A+ PPP  E + +P  T      PGE S+      P ++ P    PV  S    
Sbjct: 1191 VATSTEASSPPPTAEVTSMPTST------PGERST------PLTSMPVRHTPVASSEAST 1238

Query: 1307 FPAPPL 1312
                P+
Sbjct: 1239 LSTSPV 1244



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 234/1107 (21%), Positives = 406/1107 (36%), Gaps = 136/1107 (12%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSA-TPEPVTDNRDVE 369
            +T  +   SP  +  +  P+ T SE          S +P   SE S  +  PV  N  V 
Sbjct: 1428 TTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVV 1487

Query: 370  D---MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPT-------ENISKASSCTPV 419
                +  S    +G+ I +      P+E S   TS+P   T        ++S   + T  
Sbjct: 1488 TSTAVSSSPTPAEGTSIAIST----PSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST 1543

Query: 420  PVTM---------TATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNT 470
            PVT          TA     +    S   +P  +LP    + ++  ++ LS+ T +   T
Sbjct: 1544 PVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLST-TPIDSKT 1602

Query: 471  GVSPASRPSPGTPTSPSNLT-------SGLKTPAPATTTS-HNPLANILSKVEITPESIL 522
             V+ ++  S  T    S++T       S L T  P +TT   +P A+ LS   +   S +
Sbjct: 1603 QVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPV 1662

Query: 523  SALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSA 582
               ++  +   PA +G S    + T    P +    ++T    A++ +ST+    + +S 
Sbjct: 1663 ITSTEVSSSPTPA-EGTSMPTSTYTEGRTPLTSITVRTTPV--ASSAISTLSTTPVDNST 1719

Query: 583  QPFIPKSFNYSPNSSTSEVSSTSASKASIGQSP--GLP-STTFKLPSNSLGFTAT--HNT 637
                      SP  +TSE +S   S  S G +P   +P STT  L S +   +AT    +
Sbjct: 1720 PVTTSTEARSSP--TTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTS 1777

Query: 638  SPAAPPTEVT----ICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNL-----N 688
            +P    TE T      + + +    L SE  +P     + + L  N   S L+      N
Sbjct: 1778 TPVTTSTEATSSPTTAEGTSIPTSTL-SEGMTPLTSTPVSHTLVANSEASTLSTTPVDSN 1836

Query: 689  IPILSSLG-SSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKP--TSS 745
             P+++S   SS+P+ +  +       S     +   PV      +   + +   P  TS+
Sbjct: 1837 SPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTST 1896

Query: 746  SVDTMSLLSK--IISPGSSTPSST----RSPPPGRDESYPRELSNSVSTYRPFGLGSESP 799
             V T + +S     + GSS P+ST    R P      S     S+ ++T       + +P
Sbjct: 1897 PVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTP 1956

Query: 800  YKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILK 859
                S     P++   +S     P  ++ E          G  P   M     P  + L 
Sbjct: 1957 VTTYSQASSSPTTADGTSM----PTPAYSE----------GSTPLTSM-----PLSTTLV 1997

Query: 860  SSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVR 919
             S  + T    P+ +S        G  S       ++  S+ + +R +   G+  + ++ 
Sbjct: 1998 VSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPS-ERTTPLAGMPVSTTLV 2056

Query: 920  GNEPGSDRSPSP--SKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPD-SPHPVPHRSLFS 976
             +  G+  S +P  SK     + +++ ++ ++ ++  +S P +  P  +  P+    + S
Sbjct: 2057 VSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVAS 2116

Query: 977  PQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPS 1036
            P+ +  + T   P      V+ ST  ++S I  +      S            P   T  
Sbjct: 2117 PEASTLSTT---PVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVV 2173

Query: 1037 DGVSLSNL-TQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGA------PIETLG 1089
               ++S L T P  T+T      E     T  +S    +P ST  +G+      P+ T+ 
Sbjct: 2174 ASSAISTLSTTPVDTSTPVTNSTEARSSPT--TSEGTSMPTSTPSEGSTPFTSMPVSTMP 2231

Query: 1090 YHSASNRRMSGEPIQTVESIRVPGKGNRGHGR-EASRVGWFDLSTSGSSFDNGPSSASEL 1148
              ++    +S  P+ T   +    +        E + +    LS   +   + P S + +
Sbjct: 2232 VVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLV 2291

Query: 1149 ASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHG-TPFQR 1207
            A+        ++   T P     P    +  S    +   T    +P S    G TP  R
Sbjct: 2292 AN------SEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGT---SMPTSTSSEGNTPLTR 2342

Query: 1208 EPVGPS----------------SAPPVPPKDHGGIFSRDAP-THLPSVDLSNPFTKEAAL 1250
             PV  +                ++ PV      G     A  T +P+   S   T   ++
Sbjct: 2343 MPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSV 2402

Query: 1251 AHAAPPPPPGE---HSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPF 1307
              +  P    E   HS  P  T  P     E SSS  +    S P  PP      G  P 
Sbjct: 2403 PVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPP----SEGTTPL 2458

Query: 1308 PAPPLAEHGV----AGAVAVFPKDHSS 1330
             + P++   V    AG ++  P D S+
Sbjct: 2459 ASMPVSTTPVVSSEAGTLSTTPVDTST 2485



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 253/1060 (23%), Positives = 387/1060 (36%), Gaps = 173/1060 (16%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSES---PFQGMGGEESQSPTMESEKSATPEPVTDNRD 367
            ST P    +PV + +    SPT SE    P    G  E  +P      S TP   ++ R 
Sbjct: 886  STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPG--EGSTPLTSMPDSTTPVVSSEART 943

Query: 368  VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTK-PTENISKASSCTPVPVTMTAT 426
                 LS    D S  +    +   +  +A  TS+PT  P+E  +  +S TPV  T+ A 
Sbjct: 944  -----LSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTS-TPVSHTLVAN 997

Query: 427  ------PPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSP 480
                     P   NT L+ S   + P       A+ +S+ +S  S     G +P +R   
Sbjct: 998  SEASTLSTTPVDSNTPLTTSTEASSP----PPTAEGTSMPTSTPS----EGSTPLTRMPV 1049

Query: 481  GTPTSPSNLTSGLK-TPA----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPA 535
             T    S+ TS L  TPA    P TT S    ++  +     P S  S    T   S P 
Sbjct: 1050 STTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSE-GSTPLTSVPV 1108

Query: 536  LQGL--SSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYS 593
               L  SS   +++  PV  S   + ST AS + TT    +G ++P+S            
Sbjct: 1109 STRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTA---EGTSIPTS-----------P 1154

Query: 594  PNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPT-EVTICQSS 652
            P+  T+ ++S   S   +  S     +T  + S +   T+T  +SP  PPT EVT   S 
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSP--PPTAEVT---SM 1209

Query: 653  EVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGP 712
              S P    E ++P   M +               + P+ S         S  S     P
Sbjct: 1210 PTSTP---GERSTPLTSMPVR--------------HTPVAS---------SEASTLSTSP 1243

Query: 713  TSTSIDNIDGTPVRD--ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSST----PSS 766
              TS      TPV    E S +PT  E    PTS++ +  +LL+ I  P S+T    P +
Sbjct: 1244 VDTS------TPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSI--PVSTTLVTSPEA 1295

Query: 767  TRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSS------LMDSSQEK 820
            +       D   P   SN VS+      G+  P    S+G    +S      L+ SS   
Sbjct: 1296 STLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAIS 1355

Query: 821  FYPDTSFQEDEDYRDFEYSGPPP-----SAMMNLEKKPAKSILKSSKLSDTTEYQPILSS 875
                T             +   P     ++M N       + L S  +S T    P++SS
Sbjct: 1356 ILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT----PVVSS 1411

Query: 876  YSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKND 935
             +       V ++ P +  A           +SSP      S+  + P   ++P  S   
Sbjct: 1412 EASTLSATPVDTSTPGTTSA---------EATSSPTTAEGISIPTSTPSEGKTPLKSIPV 1462

Query: 936  SFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTG---HPPTSG 992
            S  TP +N  + + STT           DS  PV   +  S   T A  T      P+ G
Sbjct: 1463 S-NTPVANSEASTLSTTP---------VDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEG 1512

Query: 993  VEKVLASTISTT--STIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLT 1050
               + +  +STT  ++ E  ++    +   +    + QA S  T +DG S+   T    +
Sbjct: 1513 STALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGS 1572

Query: 1051 ATDQQQQEEHYRIETRVSSSCLDLP-DSTEEKGAPIETLGYHSASNRRMS------GEPI 1103
                        + +  +++    P DS  +  A  E     +A    M+      G P+
Sbjct: 1573 TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL 1632

Query: 1104 QTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFK 1163
             T     +P         EAS      LST+    ++   +++E++S      G  T   
Sbjct: 1633 LT----SIPVSTTPVASPEAS-----TLSTTPVDSNSPVITSTEVSSSPTPAEG--TSMP 1681

Query: 1164 TAPYKE-RAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKD 1222
            T+ Y E R P    +V   R+    S+    L  +P+++ TP        SS    P   
Sbjct: 1682 TSTYTEGRTPLTSITV---RTTPVASSAISTLSTTPVDNSTPVTTSTEARSS----PTTS 1734

Query: 1223 HGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSS 1282
             G       P+   +   S P +    L+  A        S  P  T  P     E +SS
Sbjct: 1735 EGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEA-----STLSATPIDTSTPVTTSTEATSS 1789

Query: 1283 ----GGSGVPFST-----PPPPPPPVDHSGVVPFPAPPLA 1313
                 G+ +P ST      P    PV H+ V    A  L+
Sbjct: 1790 PTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLS 1829



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 222/1005 (22%), Positives = 362/1005 (36%), Gaps = 119/1005 (11%)

Query: 349  PTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTE 408
            P M    S  PE  +    +E    SD     S  +        +E ++ ST++    TE
Sbjct: 79   PRMYLSCSTNPEMTS----IESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTE 134

Query: 409  NISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMK 468
            + S  S  TP    +  + P  + ++++++      LP+            +S+  +   
Sbjct: 135  DTS--SPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTST 192

Query: 469  NTGVSPASRPSPGTPTSPSNLTSGLKTPAPATT---TSHNPLANILSKVEITPESILSAL 525
                SP +  S   P S ++  S   T  PA+T    S   +  + + VEI+    +SA 
Sbjct: 193  QASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQ 252

Query: 526  SKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPF 585
            + +   +A     LS+   S    P+     +     +S A+T  +T    N+P      
Sbjct: 253  ASSSPTTAEG-PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIP------ 305

Query: 586  IPKSFNYSPNSSTSEVSSTSASKASIGQSP--GLPSTTFKLPSNSLGFTATHNTSPAAPP 643
            +  S   S + +T+E +S   S  + G +P    P++T  + ++ +   +T + +P    
Sbjct: 306  VITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEM---STLSITPVDTS 362

Query: 644  TEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSES 703
            T VT   S+E S     +E+TS    M      +G+   + + ++  +++S  +S  S +
Sbjct: 363  TLVT--TSTEPSSLPTTAEATS----MLTSTLSEGSTPLTNMPVSTILVASSEASTTS-T 415

Query: 704  HPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSST 763
             P D +   T+ S  +   T   D    T T  E     TS  V T  + S   S  S+T
Sbjct: 416  IPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTT 475

Query: 764  P-----------SSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSS 812
            P            ++ SPP     S P    +  ST     L S S    P    E  S+
Sbjct: 476  PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGST----PLTSMSVSTMPVASSE-AST 530

Query: 813  LMDSSQEKFYPDTSFQEDEDYRDFEY-----SGPPPSAMMNLEKKPAKSILKSSKLSDTT 867
            L  +  +   P T+  E              +  P      L   P  + L  S  + TT
Sbjct: 531  LSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTT 590

Query: 868  EYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDR 927
               P   S +         S+   +    + +S   +R ++   +  + ++  +   S  
Sbjct: 591  STTP-ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTL 649

Query: 928  SPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGH 987
            S +P  +++  T  +   S S +  G  S+P   Y +   P+       P NT    +  
Sbjct: 650  STTPVDSNTPVTTSTEATSSSTTAEG-TSMPTSTYTEGSTPLTS----MPVNTTLVASSE 704

Query: 988  PPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDG--------V 1039
              T     V  ST  TTST         AS  P+     G +    TPS+G        V
Sbjct: 705  ASTLSTTPVDTSTPVTTST--------EASSSPTTAD--GASMPTSTPSEGSTPLTSMPV 754

Query: 1040 SLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMS 1099
            S + LT    +       +    I T   +SC   P +TE    PI T            
Sbjct: 755  SKTLLTSSEASTLSTTPLDTSTHITTSTEASC--SPTTTEGTSMPIST---------PSE 803

Query: 1100 GEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGL 1159
            G P+ T     +P         EAS      LST+    ++  ++++E++S      G  
Sbjct: 804  GSPLLT----SIPVSITPVTSPEAS-----TLSTTPVDSNSPVTTSTEVSSSPTPAEG-- 852

Query: 1160 TGFKTAPYKE-RAPQFQESVG-SFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPP 1217
            T   T+ Y E R P     V  +  + S  ST    L  +P++  TP        SS   
Sbjct: 853  TSMPTSTYSEGRTPLTSMPVSTTLVATSAIST----LSTTPVDTSTPVTNSTEARSS--- 905

Query: 1218 VPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPG 1277
             P    G       PT  P  + S P T                 S  P  T  P     
Sbjct: 906  -PTTSEG----TSMPTSTPG-EGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTST 959

Query: 1278 EHSSS----GGSGVPFSTP-----PPPPPPVDHSGVVPFPAPPLA 1313
            E +SS     G+ +P STP     P    PV H+ V    A  L+
Sbjct: 960  EATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLS 1004



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1044 (21%), Positives = 362/1044 (34%), Gaps = 143/1044 (13%)

Query: 309  LKSTLP--DPEESPVPSPSMDAPSP--TGSESPFQGMGGEESQSPTMESEKSATP---EP 361
            L STLP    E S V + ++D   P  T +E+       E +  PT    +++TP    P
Sbjct: 2757 LVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMP 2816

Query: 362  V--TDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPV 419
            V  T     E   LS    D S  +    K   +  +A    VP       S   +  PV
Sbjct: 2817 VNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPV 2876

Query: 420  PVTMTA--------TPPLPK--PVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKN 469
              T  A        T P+    PV TS   S +       ++ ++  S + + LTS++ +
Sbjct: 2877 STTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVS 2936

Query: 470  TGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQ 529
            T V  A   +    T+P +  + + T A A+++     A   S    TP    + L+   
Sbjct: 2937 T-VPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTT--AEGTSMPISTPGERRTPLTSMS 2993

Query: 530  TQSAPALQGLSSLLQSV---TGNPVPAS-EAASQSTSASPANTTVSTIKGRNLPSSAQPF 585
              + P     +S L      T  PV  S EA+S  T+A      +ST    + P ++ P 
Sbjct: 2994 VSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPV 3053

Query: 586  ------IPKSFNYS--------PNSSTSEVSSTSA---------SKASIGQSP--GLPST 620
                  IP++   S        P  +++EVSS+           S  S G +P  G+P +
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113

Query: 621  TFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNP 680
            T  + S+++   +T     + P T  T   SS  +       +++PS         +G+ 
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS---------EGST 3164

Query: 681  GFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMD 740
              + + ++  ++ S   S  S + P D    P +TS +    T        T T  E M 
Sbjct: 3165 PLTYMPVSTMLVVSSEDSTLSAT-PVDTST-PVTTSTEATSSTTAEGTSIPTSTPSEGMT 3222

Query: 741  KPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPY 800
              TS  V    + S   S  S+TP          D + P   S   S+  P   G+  P 
Sbjct: 3223 PLTSVPVSNTPVASSEASILSTTPV---------DSNTPLTTSTEASSSPPTAEGTSMPT 3273

Query: 801  KQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKS 860
              PS+G    +S+  S+      +TS                      L   PA +    
Sbjct: 3274 STPSEGSTPLTSMPVSTTTVASSETS---------------------TLSTTPADTSTPV 3312

Query: 861  SKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRG 920
            +  S  +   PI    S         S +      L + S      S++P +    S   
Sbjct: 3313 TTYSQASSSPPIADGTSMPT------STYSEGSTPLTNMS-----FSTTPVVSSEASTLS 3361

Query: 921  NEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNT 980
              P    +P  +  ++         SLS +T    S+P     +   P+       P +T
Sbjct: 3362 TTPVDTSTPVTTSTEA---------SLSPTTAEGTSIPTSSPSEGTTPLAS----MPVST 3408

Query: 981  LAAPTGHPPTSGVEKVLASTISTTST-IEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGV 1039
                +    T     V ++T+ TTST       +   +  P+     G  P    P    
Sbjct: 3409 TPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTT 3468

Query: 1040 SLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMS 1099
             +++    +L+ T               SS     P + E    P  T G  S     ++
Sbjct: 3469 PVASSEASTLSTTPVDTS-----TPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTP---LT 3520

Query: 1100 GEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPS----SASELASLGGGG 1155
              P+ T      P   +       + V      TS S   + P+    +   +++   G 
Sbjct: 3521 NMPVST-----TPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGS 3575

Query: 1156 SGGLTGFKTAPYKERAPQFQESVGSF-RSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSS 1214
            S   T   ++ Y   +     S  S  RS    ++ + +  P+P E  T     P   S+
Sbjct: 3576 SSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVST 3635

Query: 1215 APPVPPKDHGGIFSRDAPT--HLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFP---- 1268
               + P     +   +A T   LP VD S P      ++ ++P  P G    I  P    
Sbjct: 3636 PLTIMPVSTTSVTISEAGTASTLP-VDTSTPVITSTQVS-SSPVTPEGTTMPIWTPSEGS 3693

Query: 1269 TPPPPPPPGEHSSSGGSGVPFSTP 1292
            TP    P      +   G   STP
Sbjct: 3694 TPLTTMPVSTTRVTSSEGSTLSTP 3717



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 233/1053 (22%), Positives = 373/1053 (35%), Gaps = 163/1053 (15%)

Query: 319  SPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMES-EKSATPEPVTDNRDVEDMELSDVE 377
            +PV SP     S T  +S           SP + S E S++P P         M+ S   
Sbjct: 2112 TPVASPEASTLSTTPVDS----------NSPVITSTEVSSSPIPTEGT----SMQTSTYS 2157

Query: 378  DDGSKIIVEDRKEKPAEKSAVST--SVPTKPTENISKASSCTPVPVTMTATP---PLPKP 432
            D  + +            SA+ST  + P   +  ++ ++     P T   T      P  
Sbjct: 2158 DRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSE 2217

Query: 433  VNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSG 492
             +T  +  P   +P + +      ++ + + T V  +T  + +   + GT    S L+ G
Sbjct: 2218 GSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 2277

Query: 493  LKTPAPATTTSHNPLANI-LSKVEITP-ESILSALSKTQTQSAPALQGLSSLLQSVT--G 548
              TP  +   SH  +AN  +S +  TP +S     + T+  S P     +S+  S +  G
Sbjct: 2278 T-TPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEG 2336

Query: 549  NPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASK 608
            N        S +  AS   +T+ST      P+     +        + +T++ +S   S 
Sbjct: 2337 NTPLTRMPVSTTMVASFETSTLSTT-----PADTSTPVTTYSQAGSSPTTADDTSMPTST 2391

Query: 609  ASIGQSP--GLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSP 666
             S G +P   +P +T  + S+     +TH+T+P    T VT   S+E S     +E TS 
Sbjct: 2392 YSEGSTPLTSVPVSTMPVVSSE---ASTHSTTPVDTSTPVTT--STEASSSPTTAEGTS- 2445

Query: 667  SLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTS-IDNIDGTPV 725
                     +  +P   G     P+ S   S+ P  S     + G  ST+ +D       
Sbjct: 2446 ---------IPTSPPSEGTT---PLASMPVSTTPVVSS----EAGTLSTTPVDTSTPMTT 2489

Query: 726  RDERSGTPTQDEMMDKPTSSSVDTMSLLSKI---ISPGSSTPSSTRSPPPGRDESYPREL 782
              E S +PT  E +  P S++ +  +LL+ I    +P +S  +ST S  P  D + P   
Sbjct: 2490 STEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPV-DSNSPVVT 2548

Query: 783  SNSVSTYRPFGLGSESPYKQPSDGME---------RPSSLMDSSQEKFYP-DTSFQEDED 832
            S  +S+      G+  P    S+G           +P +  ++S     P DTS      
Sbjct: 2549 STEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTS 2608

Query: 833  YRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPS 892
                E S  P +A          S + +S  S      P+ SS      E    S  P  
Sbjct: 2609 T---ETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASS------EASTLSTTPVD 2659

Query: 893  VRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTT 952
             R L+ +S      SSSP      S+  + PG   +P  +   S  T  +N  + + STT
Sbjct: 2660 TRTLVTTSTGT---SSSPTTAEGSSMPTSTPGERSTPLTNILVST-TLLANSEASTLSTT 2715

Query: 953  GHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNM 1012
                           PV      +P  T A  +  P T+    +  ST S  ST     +
Sbjct: 2716 ---------------PV---DTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSIL 2757

Query: 1013 LKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCL 1072
            +       S+      A +  T +   S+     P  T+T+         + +  +S+  
Sbjct: 2758 VSTLPVASSE------ASTVSTTAVDTSI-----PVTTSTEASSSPTTAEVTSMPTSTPS 2806

Query: 1073 DLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLS 1132
            +   ST     P+      S+    +S  P+ T   +    K +         V     +
Sbjct: 2807 ET--STPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTA 2864

Query: 1133 TSGSSFDNG-PSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFE 1191
            + GS+     P S + +AS         +   T P     P    + GS    +   T  
Sbjct: 2865 SEGSTLLTSIPVSTTPVAS------SEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGT-- 2916

Query: 1192 HHLPPS-PLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDL----SNPFTK 1246
              +P S P E  TP     V   S  PV   +   + +    T  P        S+P T 
Sbjct: 2917 -SMPISTPSEVSTPLTSILV---STVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTA 2972

Query: 1247 EAALAHAAPPPPPGEH----------------------SGIPFPTPPPPPPPGEHSSSG- 1283
            E     + P   PGE                       S  P  T  P     E SSS  
Sbjct: 2973 EGT---SMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPT 3029

Query: 1284 ---GSGVPFSTPPPPPPPVDHSGVVPFPAPPLA 1313
               G+G+P STP     P+     +P    P+A
Sbjct: 3030 TAEGTGIPISTPSEGSTPLTS---IPVSTTPVA 3059



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 132/539 (24%), Positives = 214/539 (39%), Gaps = 92/539 (17%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSE--SPFQGMGGEESQSPTMESEKSATPEPVTDNRDV 368
            +T      +P P   +  P  T SE  +P   M    + S T+    +A+  PV  +  V
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP-VSTTSVTISEAGTASTLPVDTSTPV 3666

Query: 369  ---EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTA 425
                 +  S V  +G+ + +      P+E S   T++P   T   S   S    P  +T+
Sbjct: 3667 ITSTQVSSSPVTPEGTTMPIWT----PSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTS 3722

Query: 426  TPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASR-PSPGTPT 484
            TP     V TS     + A  +   + ++    I +  T+++ +T  +P +R P   TP+
Sbjct: 3723 TP-----VTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVST--TPVTRFPESSTPS 3775

Query: 485  SPSNLTSGLKTPA----------------PATTTSHNPLANILSKVEITPESILSALSKT 528
             PS  TS   T A                P +TTS    + +L+ V I+P S++S  S+ 
Sbjct: 3776 IPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSER--STLLTTVLISPISVMSP-SEA 3832

Query: 529  QTQSAPALQGLSSLLQSVTGNP--VPASEAASQSTSASPANTTVSTIK-GRNLPSS---- 581
             T S P     + LL S       +PA     + +  S  +T ++T+     LP+S    
Sbjct: 3833 STLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGA 3892

Query: 582  ---AQPFIPKSFNYSPNSSTSEV------SSTSASKASIGQSPGLPSTTFKLPSNSLGFT 632
               + P +  S  ++P++ T+        ++ S S  + G +PG   TT  +PS  +   
Sbjct: 3893 SIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPG---TTIFIPSTPV--- 3946

Query: 633  ATHNTSPAAPPT----EVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLN 688
             T +T+   P T       +  S+E++ P   S ST+ S       F         +   
Sbjct: 3947 -TSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT-KEFTT-----PAMTTA 3999

Query: 689  IPILSSLGSSAPSESHPSDFQRG--------------PTSTSIDNIDGTPVRDERSGTPT 734
             P+     S+APS   P    RG               TSTS+     TP   E S   T
Sbjct: 4000 APLTYVTMSTAPST--PRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTP-SSESSRPST 4056

Query: 735  QDEMMDKPT-----SSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVST 788
                   PT     SS+  T S  S  ++P + T  +TR+ P  R  S+P   + +V T
Sbjct: 4057 ITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPT 4115



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 110/498 (22%), Positives = 202/498 (40%), Gaps = 41/498 (8%)

Query: 316  PEESPVPSPSMDAPSPT--GSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMEL 373
            P E   P  SM   + T   SE+        ++ +P     ++++  P+ D   +     
Sbjct: 3276 PSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTY 3335

Query: 374  SDVEDDGSKIIVEDRKEKPAEKSAVSTS-VPTKPTENISKASSCTPVPVTMTATPPL-PK 431
            S+     + +         +E S +ST+ V T      S  +S +P     T+ P   P 
Sbjct: 3336 SEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPS 3395

Query: 432  PVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTS 491
               T L+  P    P +++      ++ + S T V  +T  S +   + GT + P++ TS
Sbjct: 3396 EGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT-SLPTSTTS 3454

Query: 492  GLKTPAPATTTSHNPLANI-LSKVEITP-ESILSALSKTQTQSAPALQGLSSLLQSVTGN 549
               TP      S  P+A+   S +  TP ++     + + T S+P    ++S+  S  G 
Sbjct: 3455 EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE 3514

Query: 550  -------------PVPASEAASQSTSASPANTTV-STIKGRNLPSSAQPFIPKSFNYSPN 595
                         PV +SEA++ ST+   +NT V S+ +  + P++ Q    +    S  
Sbjct: 3515 GSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEG 3574

Query: 596  SS--TSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQS-- 651
            SS  T+ + S++   +S   +P  PS     P      T+T + S   PP  +T+  S  
Sbjct: 3575 SSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVT----TSTQSNSTPTPPEVITLPMSTP 3630

Query: 652  SEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLG-SSAPSESHPSDFQR 710
            SEVS P      ++ S+ +       G      ++ + P+++S   SS+P     +    
Sbjct: 3631 SEVSTPLTIMPVSTTSVTIS----EAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPI 3686

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSP 770
               S     +   PV   R  T ++   +  P+  +   ++  ++ IS  ++  S+T S 
Sbjct: 3687 WTPSEGSTPLTTMPVSTTRV-TSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMS- 3744

Query: 771  PPGRDESYPRELSNSVST 788
                  S P E+S   +T
Sbjct: 3745 -----VSMPMEISTLGTT 3757



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 219/1022 (21%), Positives = 356/1022 (34%), Gaps = 140/1022 (13%)

Query: 311  STLP--DPEESPVPSPSMDAPSP--TGSESPFQGMGGEESQSPTMESEKSATP------- 359
            ST+P    E S + +  +D  +P  T +E+       E +  PT    +  TP       
Sbjct: 2228 STMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVS 2287

Query: 360  EPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPV 419
              +  N +V  +  + V+ +       +    P   +A  TS+PT  +   +   +  PV
Sbjct: 2288 HTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPP--TAEGTSMPTSTSSEGNTPLTRMPV 2345

Query: 420  PVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPS 479
              TM A+        ++LS +PA     +     A  S   +  TS+  +T  S  S P 
Sbjct: 2346 STTMVASFE-----TSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTST-YSEGSTPL 2399

Query: 480  PGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSK-TQTQSAPALQG 538
               P S   + S     + A+T S  P+         T  S     ++ T   ++P  +G
Sbjct: 2400 TSVPVSTMPVVS-----SEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454

Query: 539  LSSLLQS-VTGNPVPASEAASQSTSASPANTTVST-IKGRNLPSSAQPFIPKSFNYSPNS 596
             + L    V+  PV +SEA + ST+    +T ++T  +  + P++A+  +       P S
Sbjct: 2455 TTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVV------PIS 2508

Query: 597  STSEVSSTSASKASIGQSPGLPSTTFKLPS---NSLGFTATHNTSPAAPPTEVTICQSSE 653
            + SE S+   S         +P +T  + S   ++L  T   + SP        +  S+E
Sbjct: 2509 TASEGSTLLTS---------IPVSTTPVASPEASTLSTTPVDSNSP--------VVTSTE 2551

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
            +S     +E TS    M    + +G+     + ++   L+S  +S  S + P D     T
Sbjct: 2552 ISSSATSAEGTS----MPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT-PVDTSIPVT 2606

Query: 714  STSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTR---SP 770
            +++  +   T  +D      T  E+    TS  V TM + S   S  S+TP  TR   + 
Sbjct: 2607 TSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTT 2666

Query: 771  PPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQED 830
              G   S      +S+ T  P   G  S    P   +   ++L+ +S+      T     
Sbjct: 2667 STGTSSSPTTAEGSSMPTSTP---GERS---TPLTNILVSTTLLANSEASTLSTTPVDTS 2720

Query: 831  EDY-RDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAF 889
                   E S  P +A     +    S   +   S      P+ SS +       V ++ 
Sbjct: 2721 TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSI 2780

Query: 890  PPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTP-DSNHNSLS 948
            P +      SS     ++S P                 + +PS+  +  T    NH  ++
Sbjct: 2781 PVTTSTEASSSPTTAEVTSMP-----------------TSTPSETSTPLTSMPVNHTPVA 2823

Query: 949  QSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHP----------------PTSG 992
             S  G LS       D+  PV   +  S   T A     P                 T+ 
Sbjct: 2824 SSEAGTLSTTP---VDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP 2880

Query: 993  VEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSD------GVSLSNLTQ 1046
            V    AST+STT       +  +     S     G +    TPS+       + +S +  
Sbjct: 2881 VASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPV 2940

Query: 1047 PSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTV 1106
                A+         R     S+     P + E    PI T G        MS   +   
Sbjct: 2941 AGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVA 3000

Query: 1107 ESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGG--------GSGG 1158
             S             EAS +      TS     +  +S+S   + G G        GS  
Sbjct: 3001 SS-------------EASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTP 3047

Query: 1159 LTGFKTAPYKERAPQFQE-SVGSFRSNS-FNSTFEHHLPPSPLEHGT--PFQREPVGPSS 1214
            LT    +      P+    S     SNS   ++ E    P+P E GT  P      G + 
Sbjct: 3048 LTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAE-GTSMPISTYSEGSTP 3106

Query: 1215 APPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPP 1274
               VP        S  +      VD S P T     AH++P    G  + +P  TP    
Sbjct: 3107 LTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTE-AHSSPTTSEG--TSMPTSTPSEGS 3163

Query: 1275 PP 1276
             P
Sbjct: 3164 TP 3165



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 46/199 (23%), Positives = 85/199 (42%), Gaps = 17/199 (8%)

Query: 392  PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSP------SPALAL 445
            PA   AVST V T  TE  + ++S +    + + T     P  T+ +P      S A + 
Sbjct: 3955 PATTGAVSTPVITS-TELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPST 4013

Query: 446  PNLANVDLAKISSILSSLTSVMKNTGVSPASRP-SPGTPTS-PSNLTSGLKTPAPATTTS 503
            P   +      +S LS+ ++   +T  S  +RP +P + +S PS +TS    P      S
Sbjct: 4014 PRTTSRGCTTSASTLSATST--PHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHS 4071

Query: 504  HNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSA 563
              P     S   + PE++ +  ++T+  +       ++   +VT   VP +     + ++
Sbjct: 4072 STPPTTSASSTTVNPEAVTTMTTRTKPSTR------TTSFPTVTTTAVPTNTTIKSNPTS 4125

Query: 564  SPANTTVSTIKGRNLPSSA 582
            +P     +T  G    ++A
Sbjct: 4126 TPTVPRTTTCFGDGCQNTA 4144


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 220/979 (22%), Positives = 330/979 (33%), Gaps = 191/979 (19%)

Query: 392  PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANV 451
            PA  +  +T  P +PT     A+  T    T   T P   P  T   P+    +P+   V
Sbjct: 1366 PASTTGPTTPQPGQPTR--PTATETTQTRTTTEYTTP-QTPHTTHSPPTAGSPVPSTGPV 1422

Query: 452  DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPAT--TTSHNPLAN 509
                      + TS    T     S P    PT     ++ L TP+  T  T +H  +A 
Sbjct: 1423 ----------TATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT 1472

Query: 510  ILSKVE-----ITPESILSALSKTQTQS--APALQGLSSLLQSVTGNPVPASEAASQSTS 562
              S        I P + L A   T T     P   G S    S + N  P S  +  S++
Sbjct: 1473 SASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSST 1532

Query: 563  ASPANTTVSTIKGRNLPSSAQ------------------PFIPKS--FNYSPNSSTSEVS 602
              P  T  ST      P+S +                  PF   S     SP SST  ++
Sbjct: 1533 HHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMT 1592

Query: 603  STSASKASIGQSPGLPSTTFKLPSNSLGFTA---THNTSPAAPPTEVTICQSSEVSKPKL 659
            +TS    +   +P  P TT  LP++   F+    T +T     PT   +  S+ +    +
Sbjct: 1593 ATSFKTTTTYPTPSHPQTT--LPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHS--M 1648

Query: 660  ESESTSPSLEMKIHNFLKGNPGF----SGLNLNIPILSSLGSSAPSESHPSDFQRGP-TS 714
             + +  P   +K        P      SG +  +  L++  +S    SH S       TS
Sbjct: 1649 PTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708

Query: 715  TSIDNIDGTPVRDERSGTP--TQDEMMDKPTSSSVDTMSLLSKIISPGSST------PSS 766
            TS  NI   P     +GTP  T        + SS  T    + + S  SST       +S
Sbjct: 1709 TSTTNITPNPTS---TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTS 1765

Query: 767  TRSPPPGRDESYPR----ELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFY 822
            T S  P    +  R      +++ S+  P    + SP          P+     S     
Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSP----------PTGTTPISSTGPV 1815

Query: 823  PDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQE 882
              TSFQ    Y       P PS           S   S+ L   + +  I+ +++  A  
Sbjct: 1816 TATSFQTTTTY-------PTPSHPHTTLPTHVPSF--STSLVTPSTHTVIIPTHTQMATS 1866

Query: 883  FGVKS----AFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFF 938
              + S      PP        S +     ++P +    S     P S  +   S +  + 
Sbjct: 1867 ASIHSMPTGTIPPPTTIKATGSTH-----TAPPMTPTTSGTSQSPSSFSTAKTSTSLPYH 1921

Query: 939  TPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRS------LFSPQNTLAAPTGHPPTSG 992
            T  ++H  ++ ++T +++ P+     +  PV H +      L +P  T + PTG  P S 
Sbjct: 1922 TSSTHHPEVTPTSTTNIT-PKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS 1980

Query: 993  VEKVLASTISTTSTI---------------EFKNMLKNASRK----PSDDKHFGQAPSKG 1033
               + A++  TT+T                 F   L   S       +  +    A    
Sbjct: 1981 TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS 2040

Query: 1034 TPSDGV--------SLSNLTQPSLTATDQQQQEEHYRIETRV-------SSSCLDLPDST 1078
            TP+  V        + S  T P +T T     + H    T         SSS L    S+
Sbjct: 2041 TPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSS 2100

Query: 1079 EEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSF 1138
                +PI T   H +S    +  P+ T   +                          SSF
Sbjct: 2101 RPPSSPITTQLPHLSS----ATTPVSTTNQL-------------------------SSSF 2131

Query: 1139 DNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQE-SVGSFRSNSFNSTFEHHLPPS 1197
               PS+ S ++S               P    +PQ    SVG+  S+SF S   H    S
Sbjct: 2132 SPSPSAPSTVSSY-------------VPSSHSSPQTSSPSVGT--SSSFVSAPVHSTTLS 2176

Query: 1198 PLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAAL--AHAAP 1255
               H +          SA P+ P       S      LP   +S+PFT  A L  +    
Sbjct: 2177 SGSHSSLSTHPTTASVSASPLFPSSPAA--STTIRATLPHT-ISSPFTLSALLPISTVTV 2233

Query: 1256 PPPPGEH---SGIPFPTPP 1271
             P P  H   S I FP+ P
Sbjct: 2234 SPTPSSHLASSTIAFPSTP 2252



 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 174/789 (22%), Positives = 280/789 (35%), Gaps = 114/789 (14%)

Query: 322  PSPSMDAPSPTGSESPFQGMGGEESQS-PTMESEKSATPEPVTDNRDVEDMELSDVEDDG 380
            P P     SP    SPF   G   + S  T  +  + +    T    V     S V    
Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628

Query: 381  SKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPS 440
              +I     +     S  S    T P     KA+  T    TMT T        TS +  
Sbjct: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTS-----GTSQA-- 1681

Query: 441  PALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPAT 500
                   L++++ AK S+ L S TS         ++  +  T TS +N+T     P P +
Sbjct: 1682 -------LSSLNTAKTSTSLHSHTS---------STHHAEATSTSTTNIT-----PNPTS 1720

Query: 501  TTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQS 560
            T               TP   ++    +Q++S+ +    S+ L S T +       ++ +
Sbjct: 1721 TG--------------TPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTST 1766

Query: 561  TSASPANTTVST-IKGRNLPSSAQPFIPKSFN-YSPNSSTSEVSSTSASKASIGQSPGLP 618
            TS +P +T+  T     +  S+    +P  F  +SP + T+ +SST    A+  Q+    
Sbjct: 1767 TSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQT---- 1822

Query: 619  STTFKLPSNSLGFTATH----NTSPAAPPTEVTIC-----QSSEVSKPKLESESTSPSLE 669
            +TT+  PS+      TH    +TS   P T   I       ++  S   + + +  P   
Sbjct: 1823 TTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTT 1882

Query: 670  MKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDER 729
            +K           +G     P ++   +S  S+S PS F    TSTS+     +    E 
Sbjct: 1883 IKA----------TGSTHTAPPMTPT-TSGTSQS-PSSFSTAKTSTSLPYHTSSTHHPEV 1930

Query: 730  SGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSS---TPSSTRSPPPGRD--ESYPRELSN 784
            + T T +     P  +S  T + ++   S  SS   TP +T SPP G     S     + 
Sbjct: 1931 TPTSTTNIT---PKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTAT 1987

Query: 785  SVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDED---YRDFEYSGP 841
            S  T   +   S      P+      +SL+  S       T  Q       +     + P
Sbjct: 1988 SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVP 2047

Query: 842  PPSAMM---NLEKKPAKSILKS------SKLSDTTEYQPILSSYSHRAQEFGVKSAFPPS 892
            PP+ +    +    P  ++  S      S  S  T     +SS S   Q    +    P 
Sbjct: 2048 PPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPI 2107

Query: 893  VRALLDSSENCDRLSSSPGLFGAFS--------VRGNEPGSDRSP---SPSKNDSFFTPD 941
               L   S     +S++  L  +FS        V    P S  SP   SPS   S     
Sbjct: 2108 TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVS 2167

Query: 942  SNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTI 1001
            +  +S + S+  H SL       S HP       SP      P+    ++ +   L  TI
Sbjct: 2168 APVHSTTLSSGSHSSL-------STHPTTASVSASP----LFPSSPAASTTIRATLPHTI 2216

Query: 1002 STTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHY 1061
            S+  T+     +   +  P+   H   +      +   + S  T P+ ++  Q       
Sbjct: 2217 SSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSS--QSTTSRST 2274

Query: 1062 RIETRVSSS 1070
             + TRV +S
Sbjct: 2275 SLTTRVPTS 2283



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 214/963 (22%), Positives = 327/963 (33%), Gaps = 160/963 (16%)

Query: 416  CTP-VPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSP 474
            C P +P T    P  P+   T   P+    +               S+   ++ +TG SP
Sbjct: 1193 CVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGT------------STTIGLLSSTGPSP 1240

Query: 475  ASRPSPGTPTS----PSNLTSGLKTPA----PATTTSHNP-----------LANILSKVE 515
            +S  +P +PT     P+ LTS   T +    P  TT+  P           L +  +K  
Sbjct: 1241 SSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT 1300

Query: 516  IT------------PESILSALSKTQTQ---SAPALQGLSSLLQSVTGNPVPASEAASQS 560
            +T            P +  +A S T+T      PA  G S  L   T   +P +  A+Q+
Sbjct: 1301 VTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGT-TATQT 1359

Query: 561  TSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSS-----TSASKASIGQSP 615
            T   P   T ++  G   P   QP  P +   +   +T+E ++     T+ S  + G SP
Sbjct: 1360 TGPRP---TPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAG-SP 1415

Query: 616  GLPS------------TTFKLPSNSLGFTATH----NTSPAAPPTEVTICQSSEVSKPKL 659
             +PS            TT+  PS+      TH    +TS   P T  T+   +       
Sbjct: 1416 -VPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTH-TVITPTHAQMATS 1473

Query: 660  ESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDN 719
             S  ++P+  +     LK     +G     P ++   +S  S++H S F    T TS+ +
Sbjct: 1474 ASNHSAPTGTIPPPTTLKA----TGSTHTAPPITPT-TSGTSQAH-SSFSTNKTPTSLHS 1527

Query: 720  IDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYP 779
               +    E + T T   +   PTS+   T      +    S+T  S+R PPP    S P
Sbjct: 1528 HTSSTHHPEVTPTST-TTITPNPTSTRTRT-----PVAHTNSAT--SSRPPPPFTTHSPP 1579

Query: 780  RELS--NSVSTYRPFGLGSESPYKQPSDGMER-PSSLMDSSQEKFYPDTSFQEDEDYRDF 836
               S  +S          + + Y  PS      P+ +   S     P T       +   
Sbjct: 1580 TGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1639

Query: 837  EYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRAL 896
              S    S  M     P  + LK++  + T     + +S + +A      +    S+ + 
Sbjct: 1640 ATSASIHS--MPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH 1697

Query: 897  LDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDS---FFTPDSNHNSLSQSTTG 953
              S+ + +  S+S               ++ +P+P+   +     T      S S  +T 
Sbjct: 1698 TSSTHHAEATSTST--------------TNITPNPTSTGTPPMTVTTSGTSQSRSSFSTA 1743

Query: 954  HLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNML 1013
              S     +  S H   H  + S   T   P  +  ++G    +A T S TS        
Sbjct: 1744 KTSTSLHSHTSSTH---HPEVTSTSTTSITP--NHTSTGTRTPVAHTTSATS-------- 1790

Query: 1014 KNASRKPSD-DKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCL 1072
               SR P+    H    P+  TP         T    T T       H  + T V S   
Sbjct: 1791 ---SRLPTPFTTH--SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFST 1845

Query: 1073 DL-PDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDL 1131
             L   ST     P  T    SAS   M    I    +I+  G  +       +  G    
Sbjct: 1846 SLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSG---T 1902

Query: 1132 STSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPY--KERAPQFQESVG---SFRSNSF 1186
            S S SSF    +S S            +T   T     K  +   +  V    S  S+  
Sbjct: 1903 SQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRL 1962

Query: 1187 NSTFEHHLPP---SPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLP--SVDLS 1241
             + F  H PP   SP     P        ++  P P      +     PTH+P  S  L 
Sbjct: 1963 PTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTL-----PTHVPPFSTSLV 2017

Query: 1242 NPFTKEAAL-AHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVD 1300
             P T    +  H         HS    PT   PPP    ++        ST   PP  V 
Sbjct: 2018 TPSTHTVIITTHTQMATSASIHS---TPTGTVPPPTTLKATG-------STHTAPPMTVT 2067

Query: 1301 HSG 1303
             SG
Sbjct: 2068 TSG 2070



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 127/514 (24%), Positives = 186/514 (36%), Gaps = 57/514 (11%)

Query: 316  PEESPVPSPSMDAPSPTGSESPFQGMGGEESQSP-TMESEKSATPEPVTDN------RDV 368
            P      + S   P+P  + SP  G     S  P T  S ++ T  P   +        V
Sbjct: 1781 PVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHV 1840

Query: 369  EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPP 428
                 S V      +I+    +      A S S+ + PT  I   ++      T TA P 
Sbjct: 1841 PSFSTSLVTPSTHTVIIPTHTQM-----ATSASIHSMPTGTIPPPTTIKATGSTHTAPPM 1895

Query: 429  LPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPAS-------RPSPG 481
             P    TS SPS         +   AK S+ L   TS   +  V+P S         S G
Sbjct: 1896 TPTTSGTSQSPS---------SFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTG 1946

Query: 482  TPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPA------ 535
            T T  ++ TS   +  P   T+H+P     S    T     ++   T T   P+      
Sbjct: 1947 TRTPVAHTTSASSSRLPTPFTTHSPPTG-SSPFSSTGPMTATSFQTTTTYPTPSHPQTTL 2005

Query: 536  ---LQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTI---KGRNLPSSAQPFIPKS 589
               +   S+ L + + + V  +     +TSAS  +T   T+          S     P +
Sbjct: 2006 PTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMT 2065

Query: 590  FNYSPNSST-SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTI 648
               S  S T S  S+ +AS + I  S  LP  +   P +S   T   + S A  P   T 
Sbjct: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125

Query: 649  CQSSEVSKPKLESESTSPSLEMKIHNFLKGNP---GFSGLNLNIPILSSLGSSAPSESHP 705
              SS  S P   + ST  S     H+  + +    G S   ++ P+ S+  SS    SH 
Sbjct: 2126 QLSSSFS-PSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSG---SH- 2180

Query: 706  SDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIIS-PGSSTP 764
            S     PT+ S   +  +P+        T        T SS  T+S L  I +   S TP
Sbjct: 2181 SSLSTHPTTAS---VSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTP 2237

Query: 765  SSTRSPPPGRDESYPRELSNSVSTYRPFGLGSES 798
            SS  +       S PR    + ST+      S+S
Sbjct: 2238 SSHLASSTIAFPSTPR---TTASTHTAPAFSSQS 2268



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 114/492 (23%), Positives = 179/492 (36%), Gaps = 68/492 (13%)

Query: 322  PSPSMDAPSPTGSESPFQGMGGEESQSPT-MESEKSATPEPV----TDNRDVEDMELSDV 376
            P  ++ A   T +  P        SQSP+   + K++T  P     T + +V     +++
Sbjct: 1879 PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNI 1938

Query: 377  EDDGSKIIVEDRKEKPAEKSAVSTSVPT-----KPTENISKASSCTPVPVTM---TATPP 428
                +      R       SA S+ +PT      P    S  SS  P+  T    T T P
Sbjct: 1939 TPKHTS--TGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYP 1996

Query: 429  LPKPVNTSLSP-----SPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTP 483
             P    T+L       S +L  P+   V +   + + +S +     TG  P        P
Sbjct: 1997 TPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVP--------P 2048

Query: 484  TSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
             +    T    T  P T T+        S    T  S       T T S+  +   S L 
Sbjct: 2049 PTTLKATGSTHTAPPMTVTT--------SGTSQTHSSF-----STATASSSFISSSSWLP 2095

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSF-NYSPNS-STSEV 601
            Q+ +  P P+S   +Q    S A T VST    +   S  P  P +  +Y P+S S+ + 
Sbjct: 2096 QNSSSRP-PSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQT 2154

Query: 602  SSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTS---------PAAPPTEVTICQS- 651
            SS S   +S   S  + STT  L S S    +TH T+         P++P    TI  + 
Sbjct: 2155 SSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATL 2212

Query: 652  -SEVSKP-------KLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSES 703
               +S P        + + + SP+    + +     P       +     +  S + +  
Sbjct: 2213 PHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSR 2272

Query: 704  HPSDFQRGPTSTSI---DNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPG 760
              S   R PTS  +     + G P     + T         PT+  + T SL +   +P 
Sbjct: 2273 STSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFL-TSSLTAHGSTPA 2331

Query: 761  SSTPSSTRSPPP 772
            S+  SS  +P P
Sbjct: 2332 SAPVSSLGTPTP 2343


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 136/642 (21%), Positives = 246/642 (38%), Gaps = 21/642 (3%)

Query: 315  DPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELS 374
            D  +S   S S D+ S +   S         + S + +S  S+     +D+ D  D + S
Sbjct: 655  DSSDSSNSSNSSDS-SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713

Query: 375  DVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVN 434
            D  D  +    +      ++ S  S S  +  + + S +S  +    +  ++       +
Sbjct: 714  DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773

Query: 435  TSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLK 494
            +  S S   +  N ++       S  SS +S   ++  S  S  S  + +S S+ +S   
Sbjct: 774  SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 495  TPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPAS 554
              + ++ +S +  ++  S  + +  S  S  S +   S  +    SS   S   N    S
Sbjct: 834  DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS--DSSDSNESSNS 891

Query: 555  EAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQS 614
              +S S+++S ++++ S+    +  SS      +S N S NS++S+ S++S S  S   S
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 615  PGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHN 674
                S+     SNS   + ++++  +          SS+ S     S+S++ S      +
Sbjct: 952  NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011

Query: 675  FLKGNPGFSGLNLNIPILSSLGSSAPSESHPSD-FQRGPTSTSIDNIDGTPVRDERSGTP 733
                +      N +    SS  S +   S  SD      +S S ++ D +   D    + 
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071

Query: 734  TQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFG 793
            + D      +S S D+    +   S  SS  S +       D S   + SNS  +     
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS----- 1126

Query: 794  LGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQED-EDYRDFEYSGPPPSAMMNLEKK 852
              S+S     S      S   DSS+     D+S   D  D  D   S     +  + +  
Sbjct: 1127 --SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184

Query: 853  PAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGL 912
             +     SS  SD+++     SS S  + +    S    S     DSS++ D   S+   
Sbjct: 1185 DSSDSSDSSDSSDSSD-----SSDSSDSSDSSDSSDSSDS----SDSSDSSDSSDSNESS 1235

Query: 913  FGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGH 954
              + S   ++  +    S S + S  T DSN  S SQS +G+
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277



 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 160/830 (19%), Positives = 299/830 (36%), Gaps = 56/830 (6%)

Query: 333  GSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDM-----ELSDVEDDGSKIIVED 387
            GS+S        +S S T  S+ +       D+ D  D      + SD +   S    + 
Sbjct: 504  GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563

Query: 388  RKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPN 447
                 ++ S  ++S  +  +++ S  SS +    +  ++       ++S S   + +  +
Sbjct: 564  SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS-------DSSDSSDSSDSSDS 616

Query: 448  LANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPL 507
              + D    SS   S +S   +   S  S  S  +  S S+ +S     + ++ +S +  
Sbjct: 617  SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS-- 674

Query: 508  ANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPAN 567
                S    + +S  S+ S   + S+ + +   S   S + +   +  + S S+ +  +N
Sbjct: 675  ----SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730

Query: 568  TTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSN 627
            ++ S+    +  SS       S + S +S +S  S +S S  S   S    S+     SN
Sbjct: 731  SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790

Query: 628  SLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNL 687
            S   + + N+S ++  ++ +    S  S     S+S++ S      N             
Sbjct: 791  SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN------------- 837

Query: 688  NIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSV 747
                 SS  S +   S  SD      S S ++ D +   D  + + + D      +S+S 
Sbjct: 838  -----SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892

Query: 748  DTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGM 807
            D+ S  S      SS  S++       + S   E SNS          + S     SD  
Sbjct: 893  DS-SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS- 950

Query: 808  ERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTT 867
               S   +SS      D+S     D  D   S     +  + +   +     SS  SD++
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010

Query: 868  EYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDR 927
            +     SS S  + +    S    S  +  DSS++ D   SS     + S   ++  SD 
Sbjct: 1011 D-----SSDSSNSSDSSNSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSNSSD-SSDS 1063

Query: 928  SPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGH 987
            S S   +DS  + DS+ +S S  ++   +                S  S  +  +  +  
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123

Query: 988  PPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQP 1047
              +S       S+ S+ S+    +   + S   SD      +      SD    SN +  
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183

Query: 1048 SLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVE 1107
            S ++      +     ++  SS   D  DS++      ++     +S+   S E   + +
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS----DSSDSSDSSDSSDSNESSDSSD 1239

Query: 1108 SIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSG 1157
            S       N     ++S        +S S+ D+   S S+  S  G  +G
Sbjct: 1240 SSDSSDSSNSSDSSDSS-------DSSDSTSDSNDESDSQSKSGNGNNNG 1282



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 116/636 (18%), Positives = 229/636 (36%), Gaps = 35/636 (5%)

Query: 554  SEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQ 613
            S++     + +  N    + KG++  S +      + + S +SS S+ S +++S  S   
Sbjct: 524  SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583

Query: 614  SPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIH 673
                  ++    S+S   + + ++S ++  ++ +    S+    K ES+S+         
Sbjct: 584  DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD------ 637

Query: 674  NFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTP 733
                     S  N +    +S  S + + S+ SD     +S S D+ D +   D  + + 
Sbjct: 638  ----SKSDSSDSNSSDSSDNSDSSDSSNSSNSSD-----SSDSSDSSDSSSSSDSSNSSD 688

Query: 734  TQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFG 793
            + D      +S S D+        S  S + +S  S     + S   + SNS  +     
Sbjct: 689  SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748

Query: 794  LGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKP 853
              + S     SD      S  DSS      D+S   D +  D   S     +  + +   
Sbjct: 749  SSNSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSNSSDSN--DSSNSSDSSDSSNSSDSSN 805

Query: 854  AKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLF 913
            +     SS  SD+       SS S  + +    S    S  +   S  +    S S    
Sbjct: 806  SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865

Query: 914  GAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRS 973
             +     +   SD S S   N+S  + DS+ +S S  +    S       DS +     S
Sbjct: 866  DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN-----S 920

Query: 974  LFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKG 1033
              S +++ ++   +   S      + +  ++++ +  N   +++   S D +   +    
Sbjct: 921  SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980

Query: 1034 TPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSA 1093
              SD    S+ +  S ++      +     ++  SS+  D  +S++   +         +
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS-------SDS 1033

Query: 1094 SNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGG 1153
            S+   S +   + +S       N     ++S     D S S  S D+  SS S  +S   
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS-----DSSDSSDSSDSSDSSDSSESSDSS 1088

Query: 1154 GGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNST 1189
              S       ++   + +     S  S  S+S NS+
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 261/1139 (22%), Positives = 389/1139 (34%), Gaps = 229/1139 (20%)

Query: 396  SAVSTSVPTKPTE---NISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVD 452
            S ++ S P  P+E   N++K  S             +P P  T   P     +P      
Sbjct: 171  SVITLSAPIAPSEPKTNLNKVPS-----------EVVPNPKGTPSPPCIVSTVPYHCVTP 219

Query: 453  LAKISSILSSLTSVMKNTGVSPASRPSPGT--------PTSPSNLT-SGLKTPAPATTTS 503
            +A I S ++SL      T ++ AS     T        P +P +L+  G  +P  A + S
Sbjct: 220  MASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLS 279

Query: 504  HNPLANILSKVEIT--------PESILSALSKTQTQSAPALQGLSSLLQSVTGNP-VPAS 554
               L  + S  +          P S+ S L+     S  ++Q L     S   +P V   
Sbjct: 280  TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339

Query: 555  EAASQSTSAS--PANTTVSTIKGRN--LPSS--AQPFIPKSFNYSPNSSTSEVSSTSAS- 607
                 ST AS     + +  +  RN  +P++  A P +  S +  P++ +S   S S S 
Sbjct: 340  SVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSL 399

Query: 608  --KASIGQSP-------GLPSTTF------KLPSNSLGFTATHNTSP----AAPPT--EV 646
                S   SP         P+ T+      ++P +S+G T    T+P    AAP T  EV
Sbjct: 400  NVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEV 459

Query: 647  TICQSSEVSKPKLES-ESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHP 705
              C S  +S   + + E TSP+  +      K         L IP+   L      ++ P
Sbjct: 460  ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLP 519

Query: 706  SD-FQRGPTSTSIDNI----DGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPG 760
            S    + PT   +  +    +G P    ++G  T+ +    P    V      S      
Sbjct: 520  SSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPL---VQAAPKNSPSFQST 576

Query: 761  SSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEK 820
            SS+P    SP                +T     LG   P  +P+  M  P  +  S+   
Sbjct: 577  SSSPEIPLSPE---------------ATLAKKSLGEPLPIGKPASSMTSPLGVNSSA--- 618

Query: 821  FYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRA 880
                 S  + + Y   + +GP               +LKSS ++ T    P+        
Sbjct: 619  -----SVIKTDSYAGPDSAGP---------------LLKSSLITPTVAAFPL-------- 650

Query: 881  QEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRG-NEPGSDRSPS-----PSKN 934
                 +SA P  V        +    ++SP L G  S+   N P  + + +     P+ +
Sbjct: 651  -----ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS 705

Query: 935  DSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVE 994
            ++     S  N+ +   T  L+      P+ P  VP  SL         P G PP  G +
Sbjct: 706  ENCPVAPSPQNTCAPLATLVLA------PEIPKSVPSPSL--------PPAGTPP--GTK 749

Query: 995  KVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQ-APSKGTPSDGVSLSNLTQPSLTATD 1053
            KV    IS TS +    +  +    P++D      A SKGT +    L++   P   +  
Sbjct: 750  KV--DGISHTSALA--PVASSPKECPTEDSGASATASSKGTLT---YLADSPSPLGVSVS 802

Query: 1054 QQQQEEHYRIETRVSSSCLDLP-DSTEEKGAPIET--LGYHSASNRRMSGEPIQTVESIR 1110
             Q +    R  T+  S+  D P  +     +P+E   L  +S S +     P  T     
Sbjct: 803  PQTK----RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP 858

Query: 1111 VPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKER 1170
               KG        +      LS  G +     +    + +L     G  T     P  ++
Sbjct: 859  PSPKG------APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT-----PAPKQ 907

Query: 1171 APQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPV-PPKDHGGIFSR 1229
            AP            S  S+       +P   G P    P G  + P   PP   GG    
Sbjct: 908  APAL----------SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP--- 954

Query: 1230 DAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPG-EHSSSGGSGVP 1288
                       + P  K A    AA PP P      P P   P PP     S  GG   P
Sbjct: 955  -----------ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003

Query: 1289 ----FSTPP--PPPPPVDHSGVVPFP----APPLA-EHGVAGAVAVFPKDHSSLLQGTLA 1337
                  TPP   PP P       PFP     PP A      G+ A  P     L +G   
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP-----LPKGAPT 1058

Query: 1338 EHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGGGGGSNSSSGP 1397
                 LP P+  GGP    L G        + T P+        P    GG  + S  G 
Sbjct: 1059 TPAATLPSPK--GGPATPSLKG--------APTPPA------ATPPSPKGGPATPSPKGA 1102

Query: 1398 PLGPSHRDTISRSGIILRSPRPDFRPREPFLS-RDPFHSLKRPRPPFARGPPFFAPKRP 1455
            P+ P+      + G  L +P     P  P  +   P   L  P P  A   P   P  P
Sbjct: 1103 PMPPAATPPSPKGG--LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159



 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 161/721 (22%), Positives = 239/721 (33%), Gaps = 119/721 (16%)

Query: 314  PDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMEL 373
            P P+ +P  +P+   PSP G  +     G   + + T  S K     P            
Sbjct: 1143 PPPKGAPT-TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201

Query: 374  SDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTP----VPVTMTATPPL 429
                  G           P+ K A +T   T P+    K    TP     P T  ATPP 
Sbjct: 1202 PPSPKGGLAT--------PSPKGAPTTPAATPPSP---KGGLATPSPKGAPTTPAATPPS 1250

Query: 430  PKPVNTSL----SPSPALALPNLANVDLA----KISSILSSLTSVMKNTGVSPASRPSPG 481
            PK    +     +P+P  A P      LA    K +   + +T      G  PA+ P  G
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG--PATSPPKG 1308

Query: 482  TPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSS 541
             PT P+        P+P  +    P     +   +TP S     + T   + P+ +G  +
Sbjct: 1309 APTPPA-----ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG--TPTLPATTPSSKGGPT 1361

Query: 542  LLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPS-----SAQPFIPKSFNYSPNS 596
               S  G   P   AA+ S    PA T  S  +G  +PS     ++   IP S   +P +
Sbjct: 1362 TPSSKEG---PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418

Query: 597  STSEVSSTSASKASIGQSPGLPSTTFKLPSNSL--GFTATHNT------------SPAAP 642
              +   + + SK  +      P +  K P+ S   G  AT ++            SP  P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478

Query: 643  PTEVTICQSSEVSK-PKLESESTSPSLEMKIHNFLKGNPGFSGLNLN--IPILSSLGSSA 699
            P    +  SS   K P   +   +P+L   I +  K  P       +   P  + L    
Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538

Query: 700  PSESHPSDFQRGPTST--SIDNIDGTPVRDERSGTPTQDEMMDKPT---SSSVDTMSLLS 754
            P+   P +    P  T  S       P   E   TP+  E    P    S+     S   
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598

Query: 755  KIISPGSSTPSSTRSP-PPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSL 813
             +I P  ++PS   +P PP      P +           G  + +P   P+     PSSL
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEK-----------GPATPAPKGTPTSPPVTPSSL 1647

Query: 814  MDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPIL 873
             DS                          P A   L  K   + LK   ++   E  PI+
Sbjct: 1648 KDSPTSPASVTCKM-----------GATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696

Query: 874  SSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEP---------- 923
            ++ + +  +    SA  P +         C   S+  G  G  S     P          
Sbjct: 1697 TAPTRKGPQTKKSSATSPPI---------CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 924  ---GSDRSPSP--------SKNDSFFTPDSNHNSLSQSTTGHLSL---PQKQYPDSPHPV 969
               G D S SP        SK  +  T  +    L +  +  +S    P    P +P PV
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807

Query: 970  P 970
            P
Sbjct: 1808 P 1808



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 244/1103 (22%), Positives = 365/1103 (33%), Gaps = 154/1103 (13%)

Query: 299  VNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSAT 358
            + NL   +  ++++   PE S     S D+P+ T S +P    G     + T  S K  T
Sbjct: 821  IGNLSSPVSPVEASFL-PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879

Query: 359  -PEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCT 417
             P   T    V ++              ++    PA K A + S+    T +  K +  T
Sbjct: 880  LPPKETPTPSVVNLPFP-----------KEGPATPAPKQAPALSM----TSSSPKKARAT 924

Query: 418  PVPVTMTATP-----PLPKPVNTSLSP--SPALALPNLANVDLAKI--SSILSSLTSVMK 468
            P P  + A+P     P P P  T  SP   PA   P  A    A    S      T   K
Sbjct: 925  PAPKGIPASPSPKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983

Query: 469  NTGVSPASR-PSP-GTPTSPSNLTSGLKTPAPATTTS--HNPLANILSKVEITPESILSA 524
                 PA+  PSP G P +PS    G  TP   T  S   +P A    K   TP +    
Sbjct: 984  GAPTPPAATPPSPKGGPATPS--PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041

Query: 525  LSKTQTQSAPALQGL----SSLLQSVTGNP-VPASEAASQSTSASP----ANTTVSTIKG 575
              K    + P  +G     ++ L S  G P  P+ + A    +A+P          + KG
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101

Query: 576  RNLPSSAQPFIPKSFNYSP---NSSTSEVSSTSASKASIGQSP--GLPSTTFKLPSNSLG 630
              +P +A P  PK    +P    + T+  ++  + K  +   P  G P+T    P +  G
Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161

Query: 631  FTAT-----HNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGL 685
              AT       T+PAA P          ++ P  +   T+P+            P     
Sbjct: 1162 GLATPPPKGAPTTPAATPPS----PKGGLATPSPKGAPTTPA----------ATPPSPKG 1207

Query: 686  NLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERS--GTPTQDEMMDKPT 743
             L  P  S  G+     + P   + G  + S      TP     S  G P        PT
Sbjct: 1208 GLATP--SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265

Query: 744  SSSVDTMSLLSKIISP---GSSTPSSTRSPPP--GRDESYPRELSNSVSTYRPFGLGSES 798
              +    SL   + +P   G+  P+    P P  G   S P+      +   P   G  S
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG--S 1323

Query: 799  PYKQPSDGMERPSSLMDSSQE---KFYPDTSFQEDEDYRDFEYSGP-PPSAMMNLEKKPA 854
            P   P  G   P ++   S +        T   +          GP PP+A  + +  PA
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383

Query: 855  KS--------ILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRL 906
             +         + S K   T+     LS     A     + A  PS   L   +     L
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443

Query: 907  SSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFF---TPDSNHNSLSQSTTGHLSLPQKQYP 963
              +P             G   +PS SK D      TP S     +       S P+K  P
Sbjct: 1444 KKAP-------ATSAPKGGPATPS-SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA-P 1494

Query: 964  DSPHPVPHRSL-----FSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASR 1018
             +P P+   +L      SP+   A P+           L S  +  +    + ++  A  
Sbjct: 1495 ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT 1554

Query: 1019 KPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQ--QQEEHYRIETRVSSSCLDLPD 1076
             PS  K       K  P+   S    + P++T +  +     +   I   V+S       
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614

Query: 1077 STEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGS 1136
            +      P    G  + + +     P  T  S++                   D  TS +
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK-------------------DSPTSPA 1655

Query: 1137 SFDNGPSSASELASLGGGGSGGLTGFK---TAPYKERAPQFQESVGSFRSNSFNSTFEHH 1193
            S      +    AS G     G T  K    AP  E  P              +S     
Sbjct: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP 1715

Query: 1194 LPPSP-LEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTK------ 1246
            + P P  ++G+      V P+   PV          +DA +H P   L+ P +K      
Sbjct: 1716 ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA-SHSPKGPLAPPESKASTPLT 1774

Query: 1247 -----------EAALAHAAPPPPPGEHSGIPF-PTPPPPPPPGEHSSSGGSGVPFSTPPP 1294
                       E+A   AAP PP      +P  P+P P  PP +       G+   +P  
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPP----VSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK 1830

Query: 1295 PPPPVDHSGVVPFPAPPLAEHGV 1317
            P  P D   ++P   P     GV
Sbjct: 1831 PLAPADEDELLPLIPPEPISGGV 1853



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 202/961 (21%), Positives = 315/961 (32%), Gaps = 139/961 (14%)

Query: 384  IVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPAL 443
            +    KE P E S  S +  +K T      S   P P+ ++ +P   +P     S  P  
Sbjct: 763  VASSPKECPTEDSGASATASSKGTLTYLADS---PSPLGVSVSPQTKRPPTKKGSAGPDT 819

Query: 444  ALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTS 503
             + NL++      +S L   +   + +  SPA+  SP TP SP         P P+  T 
Sbjct: 820  PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP-TPPSPKG------APTPSAVTP 872

Query: 504  HNPLANILSKVEITPESILS------ALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAA 557
             +P    L   E    S+++        +    + APAL   SS  +     P P    A
Sbjct: 873  LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932

Query: 558  SQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSP-G 616
            S S   +P     +    +  P++  P       ++P    +   S     A+   SP G
Sbjct: 933  SPSPKGAPTPPAATPPSPKGGPATPSP------KWAPTPPAATPPSPKGGPAT--PSPKG 984

Query: 617  LPSTTFKLPSNSLGFTATHNTSPAAPPTEVT--ICQSSEVSKPKLESESTSPSLEMKIHN 674
             P+     P +  G  AT +   A  P  VT    + S  + P  +  ST P+       
Sbjct: 985  APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP- 1043

Query: 675  FLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERS--GT 732
              KG+P  + L    P       + P+ + PS  + GP + S+      P     S  G 
Sbjct: 1044 --KGSPAATPLPKGAP-------TTPAATLPSP-KGGPATPSLKGAPTPPAATPPSPKGG 1093

Query: 733  PTQDEMMDKPTSSSVDTMSLLSKIISP----GSSTPSSTRSPPPGRDESYPRELSNSVST 788
            P        P   +    S    + +P      +TP++T   P G   + P + + +   
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153

Query: 789  YRP----FGLGSESPYKQPSDGMERPSSL---MDSSQEKFYPDTSFQEDEDYRDFEYSGP 841
              P     GL +  P   P+     P S    + +   K  P T             +  
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP------------AAT 1201

Query: 842  PPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSE 901
            PPS    L     K    +   +  +    + +     A      +A PPS +     + 
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT--TPAATPPSPKG--GPAT 1257

Query: 902  NCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQ 961
               + + +P      S++G         +P  N +  TP S     + S       P   
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAP--NPAVVTPPSPKGGPATSPPKGAPTPPAA 1315

Query: 962  YPDSPHPVPHRSLFSPQNTLAAPTGHPPT-SGVEKVLASTISTTSTIEFKNMLKNASRKP 1020
             P SP   P      P+     P   PP+  G   + A+T S+          K     P
Sbjct: 1316 TPPSPKGSPGTP--PPKGAPTPPAVTPPSPKGTPTLPATTPSS----------KGGPTTP 1363

Query: 1021 SDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEE 1080
            S  +  G  P   TP      S+   P++T    ++                  P     
Sbjct: 1364 SSKE--GPTPPAATP------SHKGGPAMTPPSPKRG-----------------PAIPSP 1398

Query: 1081 KGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDN 1140
            KG P         S ++    P+ T E    P KG              DL+    +  +
Sbjct: 1399 KGDPTSP-AVIPLSPKKAPATPV-TREGAATPSKG--------------DLTPPAVTPVS 1442

Query: 1141 GPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLE 1200
               + +  A  GG  +    G  T P     P  +E     +  + +S  +    P+P+ 
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLP-AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 1201 HGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFT---KEAALAHAAPPP 1257
              T     P  P   P  P      I    APT    +    P T   KEA +  A   P
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPI----APT-ATLLSKKTPATLAPKEALIPPAMTVP 1556

Query: 1258 PPGEHSGIPFPTPPPPPPPGEHSSSGGSGVP--FSTPPPP-----PPPVDHSGVVPFPAP 1310
             P +   IP P   P  P  + +SS  +  P  +   P P     PP V        P P
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616

Query: 1311 P 1311
            P
Sbjct: 1617 P 1617



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 169/701 (24%), Positives = 259/701 (36%), Gaps = 103/701 (14%)

Query: 320  PVPSPSMDA-----PSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELS 374
            PV +PS+D       S T S S    +    S SPT      ++P        V  M +S
Sbjct: 375  PVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVS 434

Query: 375  DVEDDGSKIIVEDRKEKPAEKSAVSTSVPT--KPTENISKASSCTPV-PVTMTATPPLPK 431
             V   G+  +V       A     +  V T   P  +    S+  P  P  +   P  PK
Sbjct: 435  SV---GTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPK 491

Query: 432  PVNTSLSP------SPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTS 485
              +T ++       SP L  P     DL  + S +       K+    PAS    G P S
Sbjct: 492  EPSTQVATTLRIPVSPPLPDPE----DLKNLPSSVLVKFPTQKDLQTVPASLE--GAPFS 545

Query: 486  PSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQS 545
            P+   +GL       TT  +P   +L  V+  P++  S  S + +   P L   ++L + 
Sbjct: 546  PAQ--AGL-------TTKKDP--TVLPLVQAAPKNSPSFQSTSSSPEIP-LSPEATLAKK 593

Query: 546  VTGNPVPASEAASQSTSASPANTTVSTIKGRNL--PSSAQPFIPKSFNYSPNSSTSEVSS 603
              G P+P  + AS  TS    N++ S IK  +   P SA P + KS   +P  +   + S
Sbjct: 594  SLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLL-KSSLITPTVAAFPLES 652

Query: 604  TSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESES 663
               +        G+  TT K        T+T+ T+ A+P  E T+  + +    K  + +
Sbjct: 653  ADPA--------GVAPTTAK-------GTSTYTTT-ASPFLEGTVSLAPKNHPVKEGTLT 696

Query: 664  TSPSLEMKIHNF-LKGNPGFSGLNLNIPILS-SLGSSAPSESHPSDFQRGPTSTSIDNID 721
            T P +     N  +  +P  +   L   +L+  +  S PS S P      P +  +D I 
Sbjct: 697  TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA-GTPPGTKKVDGIS 755

Query: 722  GT----PVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISP-GSSTPSSTRSPPPGRDE 776
             T    PV       PT+D      T+SS  T++ L+   SP G S    T+ PP  +  
Sbjct: 756  HTSALAPVASSPKECPTEDSGASA-TASSKGTLTYLADSPSPLGVSVSPQTKRPPTKK-- 812

Query: 777  SYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDT--SFQEDEDYR 834
                              GS  P   P   +  P S +++S   F P+   SFQ  +D  
Sbjct: 813  ------------------GSAGP-DTPIGNLSSPVSPVEAS---FLPENSLSFQGSKDSP 850

Query: 835  DFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVR 894
               +S  PPS         A + L    ++   +  P  S  +    + G  +  P    
Sbjct: 851  ATTHSPTPPSP-KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 895  ALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGH 954
            AL  +S +  +  ++P   G        P S  SP  +      TP S     +  +   
Sbjct: 910  ALSMTSSSPKKARATPAPKGI-------PASP-SPKGAPTPPAATPPSPKGGPATPSPKW 961

Query: 955  LSLPQKQYPDSPH-----PVPHRSLFSPQNTLAAPTGHPPT 990
               P    P SP      P P  +   P  T  +P G P T
Sbjct: 962  APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 221/1035 (21%), Positives = 335/1035 (32%), Gaps = 164/1035 (15%)

Query: 314  PDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKS--ATPEPVTDNRDVEDM 371
            P P+ +P P P+   PSP G  +     G     + T  S K   ATP P          
Sbjct: 957  PSPKWAPTP-PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP---KGAPTPP 1012

Query: 372  ELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTP--VPVTMTATPPL 429
             ++     GS          P  K A +    T P+   S A++  P   P T  AT P 
Sbjct: 1013 AVTPPSPKGSPAAT------PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066

Query: 430  PK--PVNTSL--SPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTS 485
            PK  P   SL  +P+P  A P       A                  SP   P P   T 
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPAT----------------PSPKGAPMPPAATP 1110

Query: 486  PSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQS 545
            PS    GL TP P       P A        TP S    L+    + AP     +     
Sbjct: 1111 PSP-KGGLATP-PHKGAPTTPAA--------TPPSPKGGLATPPPKGAPTTPAATP---- 1156

Query: 546  VTGNPVPASEAAS---QSTSASPANTTVSTIKGRNLPS-SAQPFIPKSFNYSPNSSTSEV 601
                P P    A+   +    +PA T  S   G   PS    P  P +   SP    +  
Sbjct: 1157 ----PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212

Query: 602  SSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLES 661
            S             G P+T    P +  G  AT   SP   PT       S    P    
Sbjct: 1213 SPK-----------GAPTTPAATPPSPKGGLAT--PSPKGAPTTPAATPPSPKGGPATPP 1259

Query: 662  ESTSPSLEMKIHNFLKGN---PGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSID 718
               +P+        LKG    P   G      +        P+ S P      P +T   
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP-P 1318

Query: 719  NIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSP-PPGRDES 777
            +  G+P      G PT   +   P+     T+   +     G +TPSS   P PP    S
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTP-PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377

Query: 778  YPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFE 837
            +    + +  + +  G    SP   P+     P S       K  P T    +      +
Sbjct: 1378 HKGGPAMTPPSPKR-GPAIPSPKGDPTSPAVIPLS------PKKAPATPVTREGAATPSK 1430

Query: 838  YSGPPPSAM-MNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRAL 896
                PP+   ++L+K PA S  K    + +++  P L + +  + +       PP+ + +
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE------PPAPKQV 1484

Query: 897  LDSSENCDRLSSSPGLFGAFSVRGNEPGSDRS--PSPSKNDSFFTPDSNHNSLSQSTTGH 954
              SS    +  ++P   GA ++    P S +    +PS       P +    LS+ T   
Sbjct: 1485 ATSSSP-KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT--LLSKKTPAT 1541

Query: 955  LSLPQKQYPDS---PHPVPHRSLFSPQNTLAAPTGH----PPT----------SGVEKVL 997
            L+  +   P +   P P    ++ +P+   A P+      PP           S  E ++
Sbjct: 1542 LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601

Query: 998  ASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQ 1057
               +++ S  E       A   PS +K       KGTP+       +T  SL  +     
Sbjct: 1602 PPAVTSPSPKEAPT--PPAVTPPSPEKGPATPAPKGTPTS----PPVTPSSLKDSPTSPA 1655

Query: 1058 EEHYRIETRVSSSCLDLPD------------STEEKGAPIETLGYHSASNRRMSGEPIQT 1105
                ++   V  +   LP             +   +  PI T         + S      
Sbjct: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP 1715

Query: 1106 VESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGP-SSASELASLGGGGSGGLTGFKT 1164
            +        G++G     +      +    S    G  +S S    L    S   T    
Sbjct: 1716 ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTA 1775

Query: 1165 APYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHG 1224
            A +++  P+ + +  S   +          PP  L         P+ PS  P +PPK   
Sbjct: 1776 AAFEKVLPKPESASVSAAPS----------PPVSL---------PLAPSPVPTLPPKQQF 1816

Query: 1225 GIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPP--------------PPGEHSGIPFPTP 1270
               S       PS  L+ P  ++  L    P P              P  + +GIP PTP
Sbjct: 1817 LPSSPGLVLESPSKPLA-PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTP 1875

Query: 1271 PPPPPPGEHSSSGGS 1285
                P  +++   G+
Sbjct: 1876 SAKQPVTKNNKGSGT 1890



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 234/1104 (21%), Positives = 369/1104 (33%), Gaps = 181/1104 (16%)

Query: 412  KASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTG 471
            K +  +  P+ + A  P     +++  P+   + P++A  +   + ++ + +      T 
Sbjct: 128  KGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTN 187

Query: 472  VSPASR---PSP-GTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALS- 526
            ++       P+P GTP+ P  +++    P    T   +  + + S  + TP + L+  S 
Sbjct: 188  LNKVPSEVVPNPKGTPSPPCIVST---VPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244

Query: 527  --KTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLP----- 579
              K  T S+  +   +    S+ G PV    A S ST + P  T+     G N P     
Sbjct: 245  QVKDTTISSVLISPQNPGSLSLKG-PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPI 303

Query: 580  ---SSAQPFIPKSFNY-------SPNS-STSEVSSTSASKASIGQS--------PGLPST 620
               S   P    SF          P++ S   V + S   +S G S        P LPS 
Sbjct: 304  SLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSR 363

Query: 621  TFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNP 680
               +P+    F     +    P T  +I  S   S     S S SP+  +     LK +P
Sbjct: 364  NEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL----ILKSSP 419

Query: 681  GFS---GLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDE 737
              +    L   +P+ SS+G++    ++P      PT+T       T V    S  P  + 
Sbjct: 420  NATYHYPLVAQMPV-SSVGTTPLVVTNPCTIAAAPTTTFEV---ATCVSPPMSSGPISNI 475

Query: 738  MMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSP--PPGRDESYPRELSNSVSTYRPFGLG 795
               +PTS +   M+ ++    P +   ++ R P  PP  D    + L +SV    P    
Sbjct: 476  ---EPTSPAALVMAPVAPK-EPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFP---- 527

Query: 796  SESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPS-AMMNLEKKPA 854
                     D    P+SL  +         + ++D        + P  S +  +    P 
Sbjct: 528  ------TQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE 581

Query: 855  KSILKSSKLSDTT--EYQPILSSYSHRAQEFGVKS----------AFPPSVRALLDSSEN 902
              +   + L+  +  E  PI    S      GV S          A P S   LL SS  
Sbjct: 582  IPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLI 641

Query: 903  CDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQY 962
               ++       AF +   +P    +P+ +K  S +T      + S    G +SL  K  
Sbjct: 642  TPTVA-------AFPLESADPAGV-APTTAKGTSTYT-----TTASPFLEGTVSLAPKN- 687

Query: 963  PDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSD 1022
                HPV   +L +      A    P     +   A   +     E    + + S  P+ 
Sbjct: 688  ----HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743

Query: 1023 DKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLD-LPDSTEEK 1081
                   P      DG+S ++   P  ++  +   E+     T  S   L  L DS    
Sbjct: 744  ------TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797

Query: 1082 GAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNG 1141
            G  +                     ++ R P K  +G     + +G  +LS+  S  +  
Sbjct: 798  GVSVSP-------------------QTKRPPTK--KGSAGPDTPIG--NLSSPVSPVEAS 834

Query: 1142 PSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEH 1201
                + L+  G   S   T   T P  + AP    +V          T      P+P   
Sbjct: 835  FLPENSLSFQGSKDSPATTHSPTPPSPKGAPT-PSAVTPLSPKGV--TLPPKETPTPSVV 891

Query: 1202 GTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGE 1261
              PF +E  GP++                AP   P++ +++   K+A  A  AP   P  
Sbjct: 892  NLPFPKE--GPATP---------------APKQAPALSMTSSSPKKAR-ATPAPKGIPAS 933

Query: 1262 HSGIPFPTPPPPPPPGEHSSSGGSGVP----FSTPPPPPPPVDHSGVVPFPAPPLAEHGV 1317
             S    PTPP   PP   S  GG   P      TPP   PP    G    PA P  +   
Sbjct: 934  PSPKGAPTPPAATPP---SPKGGPATPSPKWAPTPPAATPPSPKGG----PATPSPKGAP 986

Query: 1318 AGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLP--SHS 1375
                A  P                  P P+  G PT   +  P       +   P  + +
Sbjct: 987  TPPAATPPSPKGG----------PATPSPK--GAPTPPAVTPPSPKGSPAATPFPKGAST 1034

Query: 1376 LEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHS 1435
                 PP   G    +    G P  P+              P P   P  P L   P   
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPA-----------ATLPSPKGGPATPSLKGAPTPP 1083

Query: 1436 LKRPRPPFARGPPFFAPKRPFFPP 1459
               P  P   GP   +PK    PP
Sbjct: 1084 AATPPSP-KGGPATPSPKGAPMPP 1106



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 66/283 (23%), Positives = 85/283 (30%), Gaps = 27/283 (9%)

Query: 1196 PSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAP 1255
            PSP    T     P  P   P  PP           P  L     + P       A   P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 1256 PPPPGEHSGIP---FPTPP---PPPP---PGEHSSSGGSGVPFSTPPPPPPPVDHSGVVP 1306
            P P G  +  P    PTPP   PP P   PG     G    P  TPP P          P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 1307 F----PAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDL----- 1357
                 P  P ++ G     A         +     +    +P P+  G PT   +     
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK--GDPTSPAVIPLSP 1412

Query: 1358 -NGPGLSRVRESLTLPSHSLEHLGPPH----GGGGGGGSNSSSGPPLGPSHRDTISRSGI 1412
               P     RE    PS     L PP            +++  G P  PS +   +   +
Sbjct: 1413 KKAPATPVTREGAATPSKG--DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470

Query: 1413 ILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRP 1455
               SP+    P++   S  P  +   P P  A   P   P  P
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 65/271 (23%), Positives = 85/271 (31%), Gaps = 51/271 (18%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFT-KEAALAHA 1253
            PPSP E G P    P G  ++PPV P        +D+PT   SV      T  +A+    
Sbjct: 1621 PPSP-EKG-PATPAPKGTPTSPPVTPSS-----LKDSPTSPASVTCKMGATVPQASKGLP 1673

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLA 1313
            A   P      +  P P   P     +  G      S   PP        + P P+    
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP--------ICPDPSAKNG 1725

Query: 1314 EHGVAGAVAVFP-----KDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRES 1368
              G    VA  P     KD S   +G  A H      P+    P +   + P  +   E 
Sbjct: 1726 SKGPLSTVAPAPLLPVQKDSSKTAKGKDASH-----SPKGPLAPPESKASTPLTAAAFEK 1780

Query: 1369 LTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFL 1428
            +         L  P         +     PL PS              P P   P++ FL
Sbjct: 1781 V---------LPKPESASVSAAPSPPVSLPLAPS--------------PVPTLPPKQQFL 1817

Query: 1429 SRDPFHSLKRPRPPFARGPPFFAPKRPFFPP 1459
               P   L+ P  P A  P       P  PP
Sbjct: 1818 PSSPGLVLESPSKPLA--PADEDELLPLIPP 1846



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 78/331 (23%), Positives = 126/331 (38%), Gaps = 43/331 (12%)

Query: 303  KKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPV 362
            KK    LK  L  P  +P  +P + AP+  G ++         + SP +  + SA     
Sbjct: 1675 KKGPTALKEVLVAP--APESTPIITAPTRKGPQTK-----KSSATSPPICPDPSAKNGSK 1727

Query: 363  TDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVT 422
                 V    L  V+ D SK      K K A  S      P  P E  SKAS+    P+T
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTA----KGKDASHSPKG---PLAPPE--SKAST----PLT 1774

Query: 423  MTATPP-LPKPVNTSLS--PSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPA-SRP 478
              A    LPKP + S+S  PSP ++LP           S + +L    +    SP     
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLP--------LAPSPVPTLPPKQQFLPSSPGLVLE 1826

Query: 479  SPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQG 538
            SP  P +P++    L    P   +   P  ++L  +  TP+S    +     +       
Sbjct: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMP-TPKSAGIPVPTPSAKQPVTKNN 1885

Query: 539  LSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSST 598
              S  +S +   VP  E           ++T +T +   L ++A+    +  + +  S +
Sbjct: 1886 KGSGTESDSDESVPELE---------EQDSTQATTQQAQLAAAAE-IDEEPVSKAKQSRS 1935

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSL 629
             + +  + SK  + Q  G+   T +   N L
Sbjct: 1936 EKKARKAMSKLGLRQVTGVTRVTIRKSKNIL 1966


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 87/367 (23%), Positives = 130/367 (35%), Gaps = 74/367 (20%)

Query: 311  STLPDPEESPVPSPSMDA-PSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVE 369
            +T P P  +P P  S    P PT + SP        + +P+  +  + TP P T      
Sbjct: 1445 TTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT----- 1499

Query: 370  DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPL 429
                                      S  +T+  T P    +   + TP P T T T P 
Sbjct: 1500 -------------------------PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP 1534

Query: 430  PKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNL 489
            P     + +PSP    P         +    +        T   P + PSP T T+PS  
Sbjct: 1535 P-----TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589

Query: 490  T------SGLKTPAPATTTSHNPLANIL----SKVEITPESILSALSKTQTQSAPALQGL 539
            T          TP+P TTT+  P         +   ITP +  + L  T T S P     
Sbjct: 1590 TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP---- 1645

Query: 540  SSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTS 599
                 + T  P   + +   +T+ SP  TT +T      PS            SP ++T 
Sbjct: 1646 ----TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS------------SPITTTP 1689

Query: 600  EVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKL 659
               +T+ +  S   +P  P TT   PS++        T+P+ PPT +T    +    P  
Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSST--------TTPSPPPTTMTTPSPTTTPSPPT 1741

Query: 660  ESESTSP 666
             + +T P
Sbjct: 1742 TTMTTLP 1748



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 99/417 (23%), Positives = 149/417 (35%), Gaps = 64/417 (15%)

Query: 392  PAEKSAVSTSVPTK-----PTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALP 446
            P +K   + S PT      PT   +   + TP P T T T P P     + +PSP +   
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPP-----TTTPSPPITTT 1445

Query: 447  NLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNP 506
                        I ++ T     T   P + PSP T T+PS  T+   TP P TT S   
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT-TTPSPPTTTTTTPPPTTTPSPP- 1503

Query: 507  LANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPA 566
                 +   ITP +  + L  T T S P          + T  P P +  +  +T+    
Sbjct: 1504 -----TTTPITPPASTTTLPPTTTPSPPT---------TTTTTPPPTTTPSPPTTTPITP 1549

Query: 567  NTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPS 626
             T+ +T     LP +  P  P +   +P  +T               +P  P+TT   P 
Sbjct: 1550 PTSTTT-----LPPTTTPSPPPTTTTTPPPTT---------------TPSPPTTTTPSPP 1589

Query: 627  NSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLN 686
                 T    T+P+ P T  T    +    P   +  T P+    +      +P  +   
Sbjct: 1590 TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1649

Query: 687  LNIPIL--SSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPT- 743
               P    S   ++ PS    +     PT+T    I  TP        PT       PT 
Sbjct: 1650 TPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP------SPPTTTMTTPSPTT 1703

Query: 744  --SSSVDTMSLLSKIISPG-------SSTPSSTRSPPPGRDESYPRELSNSVSTYRP 791
              SS + T +  S   +P        + +P++T SPP     + P   ++S  T  P
Sbjct: 1704 TPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTP 1760



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 75/349 (21%), Positives = 127/349 (36%), Gaps = 33/349 (9%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 3989 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +             +T+V   PT   ++  + TP+  T T TP  P
Sbjct: 4049 TPTPTGTQTPTTTPI-----------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-P 4096

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPS-PGTPTSPSNL 489
             P  T    +  +              +   + T +   T V+P   P+   TPT+    
Sbjct: 4097 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4156

Query: 490  TSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQ-GLSSLLQSVTG 548
            T+   TP P  T +  P    ++    T  ++    + T TQ+ P      + + +  T 
Sbjct: 4157 TTTTVTPTPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTS 4212

Query: 549  NPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASK 608
            NP P S     S S S   T  +T     L S+  P I  +    P++ T+  +++    
Sbjct: 4213 NPPPESSTPQTSRSTSSPLTESTT-----LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHT 4267

Query: 609  ASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKP 657
             S       PSTT   P      T T ++S   P T  T   S+    P
Sbjct: 4268 LSPP-----PSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTP 4311



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 74/385 (19%), Positives = 143/385 (37%), Gaps = 37/385 (9%)

Query: 399  STSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISS 458
            +T+V   PT   ++  + TP+  T T T P P P  T    +  +              +
Sbjct: 1904 TTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1962

Query: 459  ILSSLTSVMKNTGVSPASRPS-PGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEIT 517
               + T +   T V+P   P+   TPT+    T+   TP P  T +  P          T
Sbjct: 1963 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--------T 2014

Query: 518  PESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVS-----T 572
            P +  + ++ T T +       + +  + T  P P +   +Q+ + +P  TT +     T
Sbjct: 2015 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPT 2073

Query: 573  IKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFT 632
              G   P++       +   +P  + ++  +T+    +   +P    T  + P+ +   T
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133

Query: 633  ATHNTSPAAP-----PTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNL 687
             T  T    P     PT   I  ++ V+     + + +P+               +    
Sbjct: 2134 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----------TTPITTTTT 2182

Query: 688  NIPILSSLGSSAPSE---SHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPT 743
              P  +  G+  P+    +  +     PT T       TP+    + TPT        PT
Sbjct: 2183 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2242

Query: 744  SSSVDTMSLLSKIISP-GSSTPSST 767
            ++ + T + ++   +P G+ TP++T
Sbjct: 2243 TTPITTTTTVTPTPTPTGTQTPTTT 2267



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 96/471 (20%), Positives = 172/471 (36%), Gaps = 50/471 (10%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3864

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +             +T+V   PT   ++  + TP+  T T TP  P
Sbjct: 3865 TPTPTGTQTPTTTPI-----------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-P 3912

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPS-PGTPTSPSNL 489
             P  T    +  +              +   + T +   T V+P   P+   TPT+    
Sbjct: 3913 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3972

Query: 490  TSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGN 549
            T+   TP P  T +  P          TP +  + ++ T T +       + +  + T  
Sbjct: 3973 TTTTVTPTPTPTGTQTPTT--------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4024

Query: 550  PVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKA 609
            P P +   +Q+ + +P  TT +T+     P+  Q   P +   +P ++T+ V+ T     
Sbjct: 4025 PTP-TPTGTQTPTTTPITTT-TTVTPTPTPTGTQT--PTT---TPITTTTTVTPTPTPTG 4077

Query: 610  SIGQSPG---LPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSP 666
            +  Q+P    + +TT   P+ +   T T  T+P    T VT         P      T  
Sbjct: 4078 T--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPT 4128

Query: 667  SLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVR 726
            +  +     +   P  +G         +  ++      P+  Q  PT+T I     T   
Sbjct: 4129 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPIT----TTTT 4183

Query: 727  DERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES 777
               + TPT  +      +S+     L +    P SSTP ++RS      ES
Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 4234



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 1919 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1978

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 2036

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 2037 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2095

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 2096 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 2156 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2214

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 2275 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2323

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 2103 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2162

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 2220

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 2221 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 2280 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 2340 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2398

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 2399 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2458

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 2459 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2566



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 2404

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 2405 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 2524 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2582

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2642

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 2643 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2750



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 2588

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 2589 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 2648 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 2708 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 2827 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 2772

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 2773 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2831

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 2832 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 2892 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2950

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 2951 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3010

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 3011 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3118



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 2956

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 2957 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 3076 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3134

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3194

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 3195 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3302



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 3140

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 3141 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3199

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 3200 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 3260 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3318

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 3319 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 3379 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 3324

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 3325 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3383

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 3384 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 3444 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3502

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 3503 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3562

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 3563 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3670



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 3508

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 3509 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 3568 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 3628 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3686

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 3687 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3746

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 3747 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3854



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 87/479 (18%), Positives = 174/479 (36%), Gaps = 42/479 (8%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 3692

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 3693 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3751

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 3752 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3811

Query: 544  QSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPSSAQPFIPKSFNYSPNSST 598
             + T  P P +   +Q+ + +P  TT +     T  G   P++       +   +P  + 
Sbjct: 3812 TTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3870

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAP-----PTEVTICQSSE 653
            ++  +T+    +   +P    T  + P+ +   T T  T    P     PT   I  ++ 
Sbjct: 3871 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3930

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE---SHPSDFQR 710
            V+     + + +P+               +      P  +  G+  P+    +  +    
Sbjct: 3931 VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3979

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMSLLSKIISP-GSSTPSST 767
             PT T       TP+    + TPT        PT++ + T + ++   +P G+ TP++T
Sbjct: 3980 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4038



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 72/379 (18%), Positives = 135/379 (35%), Gaps = 30/379 (7%)

Query: 316  PEESPVPSPSM--DAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P  +P+ + +     P+PTG+++P           + +PT    ++ T  P+T    V  
Sbjct: 3920 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3979

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
                      +   +          +   T  PT  T  I+  ++ TP P       P  
Sbjct: 3980 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTT 4037

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV-----SPASRPSPGTPT- 484
             P+ T+ + +P    P           +  +++T     TG      +P +  +  TPT 
Sbjct: 4038 TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4096

Query: 485  SPSNLTSGLKTPAPATTT-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +P+   +   TP   TTT +  P          TP +  + ++ T T +       + + 
Sbjct: 4097 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4156

Query: 544  QSV--------TGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIP-KSFNYSP 594
             +         TG   P +   + +T+ +P  T   T  G    +S  P     + N  P
Sbjct: 4157 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP 4216

Query: 595  NSSTSEVSSTSASKASIGQS------PGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTI 648
             SST + S +++S  +   +      P +  T+   PS     T T      +PP   T 
Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTT 4276

Query: 649  CQSSEVSKPKLESESTSPS 667
                  ++      S++P+
Sbjct: 4277 SPPGTPTRGTTTGSSSAPT 4295



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 68/317 (21%), Positives = 110/317 (34%), Gaps = 11/317 (3%)

Query: 493  LKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVP 552
            + TP+P TTT   P     S   + P +  S  + T T   P       +  + T  P  
Sbjct: 1396 ITTPSPPTTTPSPPPT---STTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452

Query: 553  ASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIG 612
                   +T+  P  TT S       P +  P  P +   +P  +T+    T+       
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512

Query: 613  QSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKI 672
             +  LP TT   P  +   T    T+P+ P T      +S  + P   + S  P+     
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572

Query: 673  HNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDN-IDGTPVRDERSG 731
                  +P  +       I ++      + S P+     P  T+  +    TP+    S 
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1632

Query: 732  TPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPS----STRSPPPGRDESYPRELSNSVS 787
            T         P  ++  T    +    P ++TPS    +T +PPP    S P   + S  
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPP 1692

Query: 788  TYRPFGLGSESPYKQPS 804
            T     + + SP   PS
Sbjct: 1693 TTT---MTTPSPTTTPS 1706



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 64/272 (23%), Positives = 102/272 (37%), Gaps = 56/272 (20%)

Query: 311  STLPDPEESPVPSPSMDA-PSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVE 369
            +TLP P  +P P P+    P PT + SP        + +P+  +  + TP P T      
Sbjct: 1554 TTLP-PTTTPSPPPTTTTTPPPTTTPSP------PTTTTPSPPTITTTTPPPTTT----- 1601

Query: 370  DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP-- 427
                                  P+  +  +T+ P   T +    +  TP   T T  P  
Sbjct: 1602 ----------------------PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639

Query: 428  -PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSP 486
             P P P  T+  P      P         I++           T   P + PS    T+P
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITT----------TTTPPPTTTPSSPITTTP 1689

Query: 487  SNLTSGLKTPAPATTTSHNPLANILSKVEIT----PESILSALSKTQTQSAPALQGLSSL 542
            S  T+ + TP+P TTT  +P+    +    T    P + ++  S T T S P    +++L
Sbjct: 1690 SPPTTTMTTPSP-TTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT-MTTL 1747

Query: 543  LQSVTGNPVPASEAASQST--SASPANTTVST 572
              + T +P+  +      T  + SP +TT  T
Sbjct: 1748 PPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 104/500 (20%), Positives = 178/500 (35%), Gaps = 80/500 (16%)

Query: 311  STLPDPEESPVPSP---SMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD 367
            +T P P  +  PSP   +   P PT + SP          + T     + TP P T    
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSP--------PTTTTTTPPPTTTPSPPTTTPI 1626

Query: 368  VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP 427
                  + +    +          P+     +T+ P  PT   S  ++ TP P   T T 
Sbjct: 1627 TPPTSTTTLPPTTT----------PSPPPTTTTTPP--PTTTPSPPTTTTPSPPITTTTT 1674

Query: 428  PLP-----KPVNTSLSP-SPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPG 481
            P P      P+ T+ SP +  +  P+      + I++  +  ++   +   +  + PSP 
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734

Query: 482  TPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSS 541
            T  SP   T    T  P TTTS +PL        ITP +     + T T     L   + 
Sbjct: 1735 TTPSPPTTTM---TTLPPTTTS-SPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTG 1790

Query: 542  LLQS-------------VTGNPVPASEAASQSTSASP---------ANTTVSTIK----G 575
             L S             + G+      AA+ S  A+            T V  +      
Sbjct: 1791 WLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLIC 1850

Query: 576  RNLPSSAQPFIPKSF--NYSPNSSTSE-VSSTSASKASIGQSPGLPSTTFKLPSNSLGFT 632
            +N        IP +F  NY  N    E V+  +    +  ++P  P+TT    + ++  T
Sbjct: 1851 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTV--T 1908

Query: 633  ATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPIL 692
             T   +    PT   I  ++ V+     + + +P+               +      P  
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----------TTPITTTTTVTPTP 1957

Query: 693  SSLGSSAPSE---SHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVD 748
            +  G+  P+    +  +     PT T       TP+    + TPT        PT++ + 
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017

Query: 749  TMSLLSKIISP-GSSTPSST 767
            T + ++   +P G+ TP++T
Sbjct: 2018 TTTTVTPTPTPTGTQTPTTT 2037



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 58/317 (18%), Positives = 119/317 (37%), Gaps = 35/317 (11%)

Query: 466  VMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSAL 525
            V + T ++  +  +P  PT+    T+   TP P  T +  P          TP +  + +
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTT--------TPITTTTTV 1930

Query: 526  SKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVS-----TIKGRNLPS 580
            + T T +       + +  + T  P P +   +Q+ + +P  TT +     T  G   P+
Sbjct: 1931 TPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1989

Query: 581  SAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPA 640
            +       +   +P  + ++  +T+    +   +P    T  + P+ +   T T  T   
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2049

Query: 641  AP-----PTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSL 695
             P     PT   I  ++ V+     + + +P+               +      P  +  
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPT 2098

Query: 696  GSSAPSE---SHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEM-MDKPTSSSVDTMS 751
            G+  P+    +  +     PT T       TP+    + TPT        PT++ + T +
Sbjct: 2099 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2158

Query: 752  LLSKIISP-GSSTPSST 767
             ++   +P G+ TP++T
Sbjct: 2159 TVTPTPTPTGTQTPTTT 2175



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 32/124 (25%), Positives = 49/124 (39%), Gaps = 11/124 (8%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            PP+      P    P  P++ P  PP     +     P+  P+   + P T   +     
Sbjct: 1525 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584

Query: 1255 PPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPP-----PPPVDHSGVVP--F 1307
             P PP   +  P PT  P PP    +++  +  P +TP PP      PP   + + P   
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPP----TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640

Query: 1308 PAPP 1311
            P+PP
Sbjct: 1641 PSPP 1644



 Score = 38.9 bits (89), Expect = 0.037
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 10/120 (8%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            PP+      P       P +  P PP       +   PT  PS   + P T   +     
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTT---TTTTPPPTTTPSPPTTTPITPPTSTTTLP 1636

Query: 1255 P---PPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
            P   P PP   +  P PT  P PP    +++    +  +T  PPP     S +   P+PP
Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSPPT---TTTPSPPITTTT-TPPPTTTPSSPITTTPSPP 1692



 Score = 38.1 bits (87), Expect = 0.063
 Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 5/117 (4%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            PP+      P    P  P++ P  PP     +     P+   +   + P T   +     
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545

Query: 1255 PPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
            P  PP   + +P  T P PPP     ++  +  P +TP PP         +    PP
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPP-----TTTTTPPPTTTPSPPTTTTPSPPTITTTTPP 1597



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 27/100 (27%), Positives = 34/100 (34%), Gaps = 6/100 (6%)

Query: 1212 PSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPP 1271
            P+S   +PP       +    T  P+   S P T          P PP   +  P PT  
Sbjct: 1410 PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTT 1469

Query: 1272 PPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
            P PP    S       P +TP PP            P+PP
Sbjct: 1470 PSPPTTTPSP------PTTTPSPPTTTTTTPPPTTTPSPP 1503



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 28/121 (23%), Positives = 43/121 (35%), Gaps = 4/121 (3%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            PP+      P    P  P++ P  PP     +     P+  P+   + P T   +     
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1663

Query: 1255 PPPPPGEHSGIPFPTPPPPPP----PGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAP 1310
             P PP   +  P PT  P  P    P   +++  +  P +TP  P            P+P
Sbjct: 1664 TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723

Query: 1311 P 1311
            P
Sbjct: 1724 P 1724



 Score = 36.2 bits (82), Expect = 0.24
 Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 3/79 (3%)

Query: 1236 PSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSS---SGGSGVPFSTP 1292
            P+   S P T    L     P PP   +  P PT  P PP    ++   +     P ST 
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461

Query: 1293 PPPPPPVDHSGVVPFPAPP 1311
              PPP    S     P+PP
Sbjct: 1462 TTPPPTTTPSPPTTTPSPP 1480



 Score = 36.2 bits (82), Expect = 0.24
 Identities = 34/128 (26%), Positives = 44/128 (34%), Gaps = 18/128 (14%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDL----SNPFTKEAAL 1250
            PP       P    P  P++  P PP       +   PT  PS  +    S P T     
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPIT---TTTTPPPTTTPSSPITTTPSPPTTTMTTP 1699

Query: 1251 AHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPP-------PPPVDHSG 1303
            +    P  P   +  P  T  P PPP   ++      P +TP PP       PP    S 
Sbjct: 1700 SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS----PTTTPSPPTTTMTTLPPTTTSSP 1755

Query: 1304 VVPFPAPP 1311
            +   P PP
Sbjct: 1756 LTTTPLPP 1763



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 58/260 (22%), Positives = 83/260 (31%), Gaps = 42/260 (16%)

Query: 1196 PSPLEHGTPFQREPVGPSSA-----PPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAAL 1250
            P P    +P    P+ P ++     P   P       +   PT  PS   + P T   + 
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553

Query: 1251 AHAAP---PPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPP---PPPVDHSGV 1304
                P   P PP   +  P PT  P PP    +++       +T PPP   P P   +  
Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPSPPT---TTTPSPPTITTTTPPPTTTPSPPTTTTT 1610

Query: 1305 VPFPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSR 1364
             P   PP           + P   ++ L  T        P P     PT      P  + 
Sbjct: 1611 TP---PPTTTPSPPTTTPITPPTSTTTLPPT------TTPSP----PPTTTTTPPPTTTP 1657

Query: 1365 VRESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRS--GIILRSPRPDFR 1422
               + T PS       PP        + ++  P   PS   T + S     + +P P   
Sbjct: 1658 SPPTTTTPS-------PPI------TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT 1704

Query: 1423 PREPFLSRDPFHSLKRPRPP 1442
            P  P  +     S   P PP
Sbjct: 1705 PSSPITTTTTPSSTTTPSPP 1724



 Score = 35.0 bits (79), Expect = 0.53
 Identities = 31/120 (25%), Positives = 39/120 (32%), Gaps = 12/120 (10%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            PP       P       P +  P PP       +   PT  PS   + P           
Sbjct: 1432 PPPTTTPSPPITTTTTPPPTTTPSPPIS---TTTTPPPTTTPSPPTTTPSPPTTT----- 1483

Query: 1255 PPPPPGEHSGIPFPTPPPPPP---PGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
             P PP   +  P PT  P PP   P    +S  +  P +TP PP            P+PP
Sbjct: 1484 -PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 224/1036 (21%), Positives = 358/1036 (34%), Gaps = 142/1036 (13%)

Query: 392  PAEKSAVSTSVPTKPT------ENISKASSCTPVPVTMTATPPL--------PKPVNTSL 437
            P E +A+S    T+ T      + IS AS  T    T+  TPP         P+    +L
Sbjct: 898  PQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTL 957

Query: 438  SPSPA------LALPNLANVDLAKISSILSSLTSVMKNTGVSPAS--RPSPGTPTSPSNL 489
            SPS +        + N   + +   SS  +  T+ +  T  S  S    +P   TSPS++
Sbjct: 958  SPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSV 1017

Query: 490  TSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQ---TQSAPALQG------LS 540
            ++G  TP P T TS     ++ + + +T  S  S    T    T ++ A  G      ++
Sbjct: 1018 STGHTTPLPVTDTSSESTGHV-TPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVT 1076

Query: 541  SLLQSVTGN--PVPASEAASQST---SASPANTTVSTIKGRNLPSSAQPFIPKSFNYS-- 593
            SL  + TG+  P+P ++ +S ST   ++ P   T S   G   P         S  ++  
Sbjct: 1077 SLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATS 1136

Query: 594  -PNSSTSEVSS--------TSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPT 644
             P + TS VS+        T AS AS GQ+  LP T       SL   +T +T+P   P 
Sbjct: 1137 LPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVT-------SLSSVSTGDTTPL--PV 1187

Query: 645  EVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESH 704
                  S+  + P L ++++S S               +G    +P+  +  SS  ++  
Sbjct: 1188 TSPSSASTGHATPLLVTDTSSAS---------------TGHATPLPVTDA--SSVSTDHA 1230

Query: 705  PSDFQRGPTSTSIDNIDGTPVRDERS---GTPTQDEMMDKPTSSSVDTMSL---LSKIIS 758
             S     P++ S  +    PV D  S   G  T   + D  + S+ DT  L    +   S
Sbjct: 1231 TSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS 1290

Query: 759  PGSSTPSSTRSP---PPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMD 815
             G  TP    SP     G     P    +S ST     L   SP    S G   P  + D
Sbjct: 1291 TGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSP-SSASTGDTTPLPVTD 1349

Query: 816  SSQEKFYPDTSFQ-EDEDYRDFEYSGP-PPSAMMNLEKKPAKSILKSSKLSDTTEYQPIL 873
            +S       T     D        + P P +++ ++       +  +S  S +T +   L
Sbjct: 1350 ASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL 1409

Query: 874  SSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNE---PGSD-RSP 929
                  +   G  +  P +      SS + D  +S P    + +  G+    P +D  S 
Sbjct: 1410 LVTDTSSASTGHATPLPVTDA----SSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSA 1465

Query: 930  SPSKNDSFFTPDSNH-----------NSLSQSTTGHLSLPQKQYPDS-------PHPVPH 971
            S  +  S    D++             S S ++TGH++      P S       P PV  
Sbjct: 1466 STGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTS 1525

Query: 972  RSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPS 1031
             S  S  +T+  P   P ++         ++  S++   +        PS        P 
Sbjct: 1526 LSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPL 1585

Query: 1032 KGTPSDGVSLSN-----LTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEK----- 1081
              T +   S  +     +T PS  +T            +  +     LP +         
Sbjct: 1586 PVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGH 1645

Query: 1082 GAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNG 1141
              P+      SAS    +  P+ +  S       + GH       G    +T  ++    
Sbjct: 1646 ATPLHVTSPSSASTGHATPLPVTSTSS------ASTGHATPLPVTGLSSATTDDTT--RL 1697

Query: 1142 PSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEH 1201
            P +    AS G      +T   +    +  P    S  S  +   +         +    
Sbjct: 1698 PVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQ 1757

Query: 1202 GTPF---QREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPP 1258
             TP        V  + A P+P        S D  T LP  D+S+     A+   A P P 
Sbjct: 1758 ATPLPVTDTSSVSTAHATPLPVTGLSSA-STDDTTRLPVTDVSS-----ASTGQAIPLPV 1811

Query: 1259 PGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVA 1318
                S     T    P P   +SS  +G   S P   P           P    +     
Sbjct: 1812 TSPSSA---STGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTG 1868

Query: 1319 GAVAVFPKDHSSLLQG 1334
             A ++   D SS+  G
Sbjct: 1869 HATSLLVTDASSVSTG 1884



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 134/543 (24%), Positives = 212/543 (39%), Gaps = 66/543 (12%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVED 370
            S++     +P+P  S+ + S TG  +P        +      S   ATP PVT    V  
Sbjct: 3399 SSVSTGHATPLPVTSLSSVS-TGDTTPLPVTDASSA------STGQATPLPVTSLSSVST 3451

Query: 371  MELSDV-EDDGSKIIVEDRKEKPA-EKSAVSTSVPTK-PTENISKASS--CTPVPVTMTA 425
             + + +   D S +        P  + S+ ST   T+ P  + S AS+   TP+PVT  +
Sbjct: 3452 GDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLS 3511

Query: 426  ------TPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPAS--R 477
                  T PL     +S+S   A  LP      +   SS  +  T+ +  T  S AS  +
Sbjct: 3512 SVSTGDTTPLLVTDASSVSTGHATPLP------VTDTSSASTGDTTRLPVTDTSSASTGQ 3565

Query: 478  PSPGTPTSPSNLTSGLKTPAPATTTS----------HNPLANILSKVEITPESILSALSK 527
             +P   T PS+ +SG  TP P T+TS          H    +  S   +TP  + S  S 
Sbjct: 3566 ATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSA 3625

Query: 528  TQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSAS---PANTTVSTIKGRNLPSSAQP 584
            +   + P L   +S + +    P+P ++A+S ST  +   P   T S   G+     A P
Sbjct: 3626 STGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQ-----ATP 3680

Query: 585  FIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSN-SLGFTATHNTSPAAPP 643
                S +      T+ +  T AS AS G +  LP T   +PS+ S G T      P   P
Sbjct: 3681 LPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVT---IPSSVSTGDTM---PLPVTSP 3734

Query: 644  TEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSES 703
            +  +   ++ +    L S ST  +  + + +    +   +      P+  +  SSA ++ 
Sbjct: 3735 SSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHA-----TPLPVTDTSSASTDD 3789

Query: 704  HPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSST 763
                     +S S  +    PV    S +      +    +SSV T    S  ++  SS 
Sbjct: 3790 TTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSA 3849

Query: 764  PSSTRSPPPGRDES---------YPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLM 814
             +   +P P  D S          P   ++SVST     L   SP    S G   P  + 
Sbjct: 3850 STGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSP-SSASTGHATPVPVT 3908

Query: 815  DSS 817
             +S
Sbjct: 3909 STS 3911



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 228/1065 (21%), Positives = 360/1065 (33%), Gaps = 156/1065 (14%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTD--NRDV 368
            S++   + +P+P  S  + S TG  +P          SP+  S   ATP PVT   +   
Sbjct: 1479 SSVSTGDTTPLPVTSTSSAS-TGHVTPLH------VTSPSSASTGHATPLPVTSLSSAST 1531

Query: 369  EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTK-PTENISKASS--CTPVPVTMTA 425
             D     V    S    +       + S+VST   T  P  + S AS+   TP+PVT T+
Sbjct: 1532 GDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTS 1591

Query: 426  ------TPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPAS--R 477
                  T PLP    +S S      LP      +   SS  +  T+ +  T  S  S   
Sbjct: 1592 SASKGDTTPLPVTSPSSASTGHTTPLP------VTDTSSASTGDTTPLPVTNASSLSTGH 1645

Query: 478  PSPGTPTSPSNLTSGLKTPAPATTTSHN--------PLANILS-KVEITPESILSALSKT 528
             +P   TSPS+ ++G  TP P T+TS          P+  + S   + T    ++ +S  
Sbjct: 1646 ATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSA 1705

Query: 529  QTQSAPALQGLSSLLQSVTGN--PVPASEAASQSTS-ASPANTT----VSTIKGRNLP-- 579
             T  A  L  ++SL    TG+  P+P +  +S ST  ASP   T     ST +   LP  
Sbjct: 1706 STGQATPLP-VTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVT 1764

Query: 580  -------SSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFT 632
                   + A P      + +    T+ +  T  S AS GQ+  LP T+   PS++    
Sbjct: 1765 DTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTS---PSSA---- 1817

Query: 633  ATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPIL 692
            +T +T+P  P T+ +   + + +   +   S++                 SG   ++P+ 
Sbjct: 1818 STGDTTP-LPVTDASSASTGDTTSLPVTIPSSAS----------------SGHTTSLPVT 1860

Query: 693  SSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSL 752
             +  SS  +    S      +S S  +    PV D  S +      +    +SSV T   
Sbjct: 1861 DA--SSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHA 1918

Query: 753  LSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSS 812
             S  ++  SS  +   +P P    + P   S+  +T  P    S  P    +      +S
Sbjct: 1919 TSLPVTSLSSASTGDTTPLP---VTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDAS 1975

Query: 813  LMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAK-SILKSSKLSDTTEYQP 871
             + +      P T                  S++   +  P   + L S+   DTT   P
Sbjct: 1976 SVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPL-P 2034

Query: 872  ILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSP 931
            +  + S      G  +  P +  + + + +      +SP                 S S 
Sbjct: 2035 VTDTSS---ASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVST 2091

Query: 932  SKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTS 991
                S    D++  S   +T  H++           P+P  S  S       P     TS
Sbjct: 2092 GHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTS 2151

Query: 992  GVEKVLASTISTTSTIE----FKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSN---L 1044
             V    A+++  T T          L       +   H    P   T S     +    +
Sbjct: 2152 SVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPV 2211

Query: 1045 TQPS---------LTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASN 1095
            T PS         L  TD             V+S    L  ++     P+      S S 
Sbjct: 2212 TSPSSASTGHAIPLLVTDTSSASTGQATPLPVTS----LSSASTGDTTPLPVTDASSVST 2267

Query: 1096 RRMSGEPIQTVESIRV----------PGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSA 1145
               +  P+ ++ S+            P   + GH             T  SS   G ++ 
Sbjct: 2268 GHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLH-------VTDASSASTGHATP 2320

Query: 1146 SELASLGGGGSGG-----LTGFKTAPYKERAPQFQESVGSFRS--------NSFNSTFEH 1192
              + SL    +G      +T   +A      P       S  +         S +S    
Sbjct: 2321 LPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSG 2380

Query: 1193 HLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFT------- 1245
            H  P P+   +             P+P  D     +  A THLP   LS+  T       
Sbjct: 2381 HTTPLPVTDAS-----SASTGDTTPLPVTDTSSASTGHA-THLPVTGLSSASTGDTTRLP 2434

Query: 1246 ----KEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSG 1286
                  A+  HA P P     S     T    P PG  +SS  +G
Sbjct: 2435 VTNVSSASTGHATPLPVTSTSSA---STGDTTPLPGTDTSSVSTG 2476



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 122/504 (24%), Positives = 191/504 (37%), Gaps = 88/504 (17%)

Query: 317  EESPVPSPSMDAPS-----PTGSESPFQGMGGEESQSPTMESEKSATPE----PVTDNRD 367
            + +P+P  S+ + S     P    SP     G  +  P  ++  ++T +    PVTD   
Sbjct: 3085 QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSS 3144

Query: 368  VE--DMELSDVEDDGSKIIVEDRKEKPAEKSAVST--SVPTKPTENISKASS-CTPVPVT 422
                D     V D  S    +       E S+VST  + P   T+  S ++   TP+ VT
Sbjct: 3145 AYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVT 3204

Query: 423  MTA------TPPLPKPVNTSLSPSPALALP----------NLANVDLAKISSILSSLTSV 466
              +      T P+P    +S+S   A  LP          +   + +  ISS  +   + 
Sbjct: 3205 SPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATP 3264

Query: 467  MKNTGVSPASRPS--PGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSA 524
            +  T  S  S     P   TSPS+ ++G  TP P T+TS        S    TP  + S 
Sbjct: 3265 LPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSS------ASTGHATPVPVTST 3318

Query: 525  LSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTS-ASPANTTVSTIKGRNLPSSAQ 583
             S +   + P     +S   +    P+P +  +S ST   +P + T+        PSSA 
Sbjct: 3319 SSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTI--------PSSAS 3370

Query: 584  PFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPST---------TFKLPSNSLGFTAT 634
                          TS +  T AS AS G +  LP T            LP  SL   +T
Sbjct: 3371 -----------TGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVST 3419

Query: 635  HNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSS 694
             +T+P  P T+ +             S ST  +  + + +    + G +      P+L +
Sbjct: 3420 GDTTP-LPVTDAS-------------SASTGQATPLPVTSLSSVSTGDT-----TPLLVT 3460

Query: 695  LGSSAPSESHPSDFQRGPTST-SIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLL 753
              SS  S  H +      TS+ S  +    PV D  S +  Q   +   + SSV T    
Sbjct: 3461 DASSV-STGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTT 3519

Query: 754  SKIISPGSSTPSSTRSPPPGRDES 777
              +++  SS  +   +P P  D S
Sbjct: 3520 PLLVTDASSVSTGHATPLPVTDTS 3543



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 233/1042 (22%), Positives = 355/1042 (34%), Gaps = 135/1042 (12%)

Query: 357  ATPEPVTDNRDVE--DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTK-PTENISKA 413
            ATP P+T    V   D     V D  S    +         S+VST   T  P  + S A
Sbjct: 2766 ATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSA 2825

Query: 414  SS--CTPVPVTMTATP------PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTS 465
            S+   T +PVT T++       PLP    +S S   A  LP    V     +SI  + + 
Sbjct: 2826 STGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLP----VTDTSSASIGHATSL 2881

Query: 466  VMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSH------NPL----ANILSKVE 515
             + +T        +P   TSPS+ ++G  TP P T TS       NPL     +  S   
Sbjct: 2882 PVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGH 2941

Query: 516  ITPESILSALSKTQTQSAP-ALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIK 574
             TP  +    S +   + P  +  LSS+    T  P+P +  +S ST  +       T  
Sbjct: 2942 ATPLPVTDTSSASTGHATPLPVTSLSSVSTGDT-TPLPVTSPSSASTGHTTPLPVTDTSS 3000

Query: 575  GRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTAT 634
                 ++A P    S + +    T+ +  T  S AS GQ+  LP T       SL   +T
Sbjct: 3001 ASTGQATALPV--TSTSSASTGDTTPLPVTDTSSASTGQATPLPVT-------SLSSVST 3051

Query: 635  HNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSS 694
             +T+P   P       S+  + P L ++++S S               +G    +P+ +S
Sbjct: 3052 GDTTPL--PVTSPSSASTGHATPLLVTDASSAS---------------TGQATPLPV-TS 3093

Query: 695  LGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERS---GTPTQDEMMDKPTSSSVDTMS 751
            L S +  ++ P      P+S S  +    PV D  S   G  T   + D  ++ + DT S
Sbjct: 3094 LSSVSTGDTTPLPV-TSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTS 3152

Query: 752  LL---SKIISPGSSTP---SSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSD 805
            L    +   S G +TP   + T S   G         ++S ST     L   SP    S 
Sbjct: 3153 LPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSP-SSAST 3211

Query: 806  GMERPSSLMDSSQEKF-----YPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKS 860
            G   P  + D+S          P T                  S+    +  P      S
Sbjct: 3212 GDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTS 3271

Query: 861  SKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRG 920
            S  +  T   P+ S  S         +     +     SS +    +  P    + +  G
Sbjct: 3272 SVSTGDTMPLPVTSPSS-------ASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTG 3324

Query: 921  NE---PGSDRSPSPSKNDSFFTPDSNHNSLS--QSTTGHLSLPQKQYPDSPHPVPHRSLF 975
            +    P +D S S S  D+   P ++ +S S   +T  H+++P          +P     
Sbjct: 3325 HTTPLPVTDTS-SASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGAS 3383

Query: 976  SPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTP 1035
            S     A P     TS V    A+ +  TS         + +  P  D     +  + TP
Sbjct: 3384 SASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVST--GDTTPLPVTDAS-SASTGQATP 3440

Query: 1036 SDGVSLSNL----TQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYH 1091
                SLS++    T P L          H        +S     D+T      +      
Sbjct: 3441 LPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTR-----LPVTDTS 3495

Query: 1092 SASNRRMSGEPIQTVESIRV----------PGKGNRGHG-----REASRVGWFDLS---- 1132
            SAS  + +  P+ ++ S+                + GH       + S     D +    
Sbjct: 3496 SASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPV 3555

Query: 1133 TSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEH 1192
            T  SS   G ++   +       SG  T     P    +      V      S +S    
Sbjct: 3556 TDTSSASTGQATPLPVTIPSSSSSGHTT---PLPVTSTSSVSTGHVTPLHVTSPSSASTG 3612

Query: 1193 HLPPSPLE--------HGTPF---QREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLS 1241
            H+ P P+         H TP        V    A P+P  D     + D  T LP  D S
Sbjct: 3613 HVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDT-TPLPVTDTS 3671

Query: 1242 NPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDH 1301
            +  T +A       P P    S +      P P     S+S G   P     P       
Sbjct: 3672 SASTGQAT------PLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGD 3725

Query: 1302 SGVVPFPAPPLAEHGVAGAVAV 1323
            +  +P  +P  A  G A  + V
Sbjct: 3726 TMPLPVTSPSSASTGHATPLPV 3747



 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 115/467 (24%), Positives = 193/467 (41%), Gaps = 48/467 (10%)

Query: 319  SPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVE- 377
            +P+P  S+ + S TG   P          SP+  S    TP PVTD   V     + +  
Sbjct: 1311 TPLPVTSLSSAS-TGDTMPLP------VTSPSSASTGDTTPLPVTDASSVSTGHTTPLHV 1363

Query: 378  DDGSKIIVEDRKEKPAEK-SAVSTSVPTK-PTENISKASS--CTPVPVTMTAT------P 427
             D S          P    S+VST   T  P  + S AS+   TP+ VT T++       
Sbjct: 1364 TDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHAT 1423

Query: 428  PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS 487
            PLP    +S+S   A +LP    V +   +S   +    + +T  +   + +    T  S
Sbjct: 1424 PLPVTDASSVSTDHATSLP----VTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTS 1479

Query: 488  NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT 547
            ++++G  TP P T+TS        S   +TP  + S  S +   + P    ++SL  + T
Sbjct: 1480 SVSTGDTTPLPVTSTSS------ASTGHVTPLHVTSPSSASTGHATPL--PVTSLSSAST 1531

Query: 548  GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQ--PFIPKSFNYSPNSSTSEVSSTS 605
            G+ +P     +  +SAS  +TT   +   +  S+    P    S + +    T+ +  T 
Sbjct: 1532 GDTMPL--PVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTD 1589

Query: 606  ASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSK-PKLESEST 664
             S AS G +  LP T+   PS++    +T +T+P  P T+ +   + + +  P   + S 
Sbjct: 1590 TSSASKGDTTPLPVTS---PSSA----STGHTTP-LPVTDTSSASTGDTTPLPVTNASSL 1641

Query: 665  SPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQ-RGPTSTSIDNIDGT 723
            S      +H     +   +G    +P+ S   +S+ S  H +     G +S + D+    
Sbjct: 1642 STGHATPLH-VTSPSSASTGHATPLPVTS---TSSASTGHATPLPVTGLSSATTDDTTRL 1697

Query: 724  PVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSP 770
            PV D  S +  Q   +   + SSV T       ++  SS  +   SP
Sbjct: 1698 PVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASP 1744



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 137/569 (24%), Positives = 219/569 (38%), Gaps = 78/569 (13%)

Query: 312  TLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKS---ATPEPVTDNRDV 368
            T P P  SP  + + D      +++     G   S   T  S  S   AT  PVTD    
Sbjct: 2126 TTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSA 2185

Query: 369  EDMELSD--VEDDGSKIIVEDRKEKPAEKSAVST--SVPTKPTENISKASS-CTPVPVTM 423
                 +   V D  S    +         S+ ST  ++P   T+  S ++   TP+PVT 
Sbjct: 2186 STGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTS 2245

Query: 424  TA------TPPLPKPVNTSLSPSPALALP--NLANVDLAK-----ISSILSSLTSVMKNT 470
             +      T PLP    +S+S   A +LP  +L++V         ++S  S+ T      
Sbjct: 2246 LSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL 2305

Query: 471  GVSPASRPSPG--TP---TSPSNLTSGLKTPAPATTTS----------HNPLANILSKVE 515
             V+ AS  S G  TP   TS S+ ++G  TP P T+ S          H   A+ +S  +
Sbjct: 2306 HVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGD 2365

Query: 516  ITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQST------------SA 563
             TP  + S+ S +   + P     +S   +    P+P ++ +S ST            SA
Sbjct: 2366 TTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSA 2425

Query: 564  SPANTTVSTIKGRNLPSS--AQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPST- 620
            S  +TT   +   +  S+  A P    S + +    T+ +  T  S  S G +  L  T 
Sbjct: 2426 STGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTD 2485

Query: 621  --------TFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKI 672
                    T +LP  S    +T +T+P  P T+     + + +   + + S+  +     
Sbjct: 2486 ASSVSTGDTTRLPVTSPSSASTGHTTP-LPVTDTPSASTGDTTPLPVTNASSLSTRHATS 2544

Query: 673  HNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTST-SIDNIDGTPVRDERSG 731
             +    +   +G   ++P+     +SA S  H +      TS+ S  +    PV D  S 
Sbjct: 2545 LHVTSPSSASTGHATSLPVTD---TSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSA 2601

Query: 732  TPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTP---SSTRSPPPGRDESYPRELSNSVST 788
            +  Q   +    +SS  T          G +TP   + T S   G     P   ++SVST
Sbjct: 2602 STGQATPLPVTDTSSAST----------GDTTPLPVTDTSSASTGHATPLPVTNTSSVST 2651

Query: 789  YRPFGLGSESPYKQPSDGMERPSSLMDSS 817
                 L   SP    S G   P  + D+S
Sbjct: 2652 GHATPLHVTSP-SSASTGHTTPLPVTDAS 2679



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 250/1149 (21%), Positives = 382/1149 (33%), Gaps = 146/1149 (12%)

Query: 315  DPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTD--NRDVEDME 372
            D    PV SPS    + TG  +P        +      S   ATP PVT   +    D  
Sbjct: 2285 DTTPLPVTSPSS---ASTGHATPLHVTDASSA------STGHATPLPVTSLSSASTGDTT 2335

Query: 373  LSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTK-PTENISKASS--CTPVPVTMTA---- 425
               V    S            + S+VST   T  P  + S ASS   TP+PVT  +    
Sbjct: 2336 PLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSAST 2395

Query: 426  --TPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPAS--RPSPG 481
              T PLP    +S S   A  LP      +  +SS  +  T+ +  T VS AS    +P 
Sbjct: 2396 GDTTPLPVTDTSSASTGHATHLP------VTGLSSASTGDTTRLPVTNVSSASTGHATPL 2449

Query: 482  TPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESIL--SALSKTQTQSAPALQGL 539
              TS S+ ++G  TP P T TS       +S    TP  +   S++S   T   P     
Sbjct: 2450 PVTSTSSASTGDTTPLPGTDTSS------VSTGHTTPLLVTDASSVSTGDTTRLPVTSPS 2503

Query: 540  SSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTS 599
            S+     T  PV  + +AS   +     T  S++  R+  S     +    + S   +TS
Sbjct: 2504 SASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSL---HVTSPSSASTGHATS 2560

Query: 600  EVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKL 659
             +  T  S AS G +  LP T     S S   T      P       +  Q++ +     
Sbjct: 2561 -LPVTDTSAASTGHATPLPVT-----STSSASTGDTTPLPVTDTYSASTGQATPLPVTDT 2614

Query: 660  ESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQ-RGPTSTSID 718
             S ST  +  + + +    + G +     +P+ ++   S+ S  H +      P+S S  
Sbjct: 2615 SSASTGDTTPLPVTDTSSASTGHA---TPLPVTNT---SSVSTGHATPLHVTSPSSASTG 2668

Query: 719  NIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPP------ 772
            +    PV D  S +      +    +SSV T    S  ++  SS  S   +P P      
Sbjct: 2669 HTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASS 2728

Query: 773  ---GRDESYPRELSNSVSTYRPFGL----------GSESP-----YKQPSDGMERPSSLM 814
               G   S P   ++SVST     L          G  +P         S G   P  + 
Sbjct: 2729 VSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVT 2788

Query: 815  DSS-----QEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEY 869
            D+S     Q    P TS          + +  P +   +     A S+  +   S +T +
Sbjct: 2789 DTSSASTGQATPLPVTSL---SSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGH 2845

Query: 870  QPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSP 929
               L      +   G  +  P     + D+S      ++S  +    S+           
Sbjct: 2846 ATPLPDTDTSSASTGHATLLP-----VTDTSSASIGHATSLPVTDTSSISTGHATPLHVT 2900

Query: 930  SPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPP 989
            SPS   +           S ++TGH + P      S     H +     +T +A TGH  
Sbjct: 2901 SPSSASTGHATPLPVTDTSSASTGHAN-PLHVTSPSSASTGHATPLPVTDTSSASTGHAT 2959

Query: 990  TSGVEKVLASTISTTST----IEFKNMLKNASRKP-----SDDKHFGQAPSKGTPSDGVS 1040
               V  +  S++ST  T    +   +        P     +     GQA +    S   +
Sbjct: 2960 PLPVTSL--SSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSA 3017

Query: 1041 LSNLTQPSLTATDQQQQEEHYRIETRVSS-SCLDLPDST-----------EEKGAPIETL 1088
             +  T P L  TD             V+S S +   D+T                P+   
Sbjct: 3018 STGDTTP-LPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVT 3076

Query: 1089 GYHSASNRRMSGEPIQTVESIRV----------PGKGNRGHGREASRVGWFDLSTSGSSF 1138
               SAS  + +  P+ ++ S+            P   + GH            ST  ++ 
Sbjct: 3077 DASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTT- 3135

Query: 1139 DNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSP 1198
             + P + +  A  G   S  +T   ++   +  P       S  +             + 
Sbjct: 3136 -SLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSAS 3194

Query: 1199 LEHGTPFQREPVGPSSA-----PPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKE------ 1247
              H TP       PSSA      PVP  D   + +  A T LP   LS+  T +      
Sbjct: 3195 TGHATPL--HVTSPSSASTGDTTPVPVTDTSSVSTGHA-TPLPVTGLSSASTGDTTRLPV 3251

Query: 1248 ----AALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSG 1303
                +A    A P P    S +      P P     S+S G   P            H+ 
Sbjct: 3252 TDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHAT 3311

Query: 1304 VVPFPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLS 1363
             VP  +   A  G    + V   D SS   G         P     G  T   +  P  +
Sbjct: 3312 PVPVTSTSSASTGHTTPLPV--TDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSA 3369

Query: 1364 RVRESLTLP 1372
               ++ TLP
Sbjct: 3370 STGDTSTLP 3378



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 103/373 (27%), Positives = 149/373 (39%), Gaps = 58/373 (15%)

Query: 319  SPVPSPSMDAPSPTGSESPFQ-------GMGGEESQSPTMESEKS---ATPEPVTDNRDV 368
            +P+P  S  + S TG  +P           G   S   T  S  S   ATP PVTD   V
Sbjct: 3807 TPLPVTSTSSAS-TGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSV 3865

Query: 369  EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTK-PTENISKASS--CTPVPVTMTA 425
                 + +    +              S+VST   T  P  + S AS+   TPVPVT T+
Sbjct: 3866 STGHATPLPVTST--------------SSVSTGHATPLPVTSPSSASTGHATPVPVTSTS 3911

Query: 426  ------TPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPAS--R 477
                  T PLP    +SLS   A  L       +   SS     TS +  T  S AS   
Sbjct: 3912 SASTGDTTPLPVTNASSLSTGHATPL------HVTSPSSASRGDTSTLPVTDASSASTGH 3965

Query: 478  PSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQ 537
             +P   TS S++++G  TP P T TS        S  + TP  + S  S +   + P   
Sbjct: 3966 ATPLPLTSLSSVSTGDTTPLPVTDTSS------ASTGQATPLPVTSLSSVSTGDTTPLPV 4019

Query: 538  GLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSS 597
             + S   S     +P ++A+S ST         ST       ++  P    S   + +++
Sbjct: 4020 TIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHAT 4079

Query: 598  TSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKP 657
               V+ TS+  AS G +  LP T       SL   +T + +P A  +  +    S  S  
Sbjct: 4080 PLPVTDTSS--ASTGHATPLPVT-------SLSSVSTGHATPLAVSSATSASTVSSDSPL 4130

Query: 658  KLESES-TSPSLE 669
            K+E+   T+PSL+
Sbjct: 4131 KMETPGMTTPSLK 4143



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 113/489 (23%), Positives = 184/489 (37%), Gaps = 75/489 (15%)

Query: 349  PTMESEKSATPEPVTDNRDVEDMELSDV-EDDGSKIIVEDRKEKPAEKSAVSTSVPTKPT 407
            P+  S    TP PVTD       + + +   D S +   D    P   ++ +++    P 
Sbjct: 1238 PSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPL 1297

Query: 408  ENISKASS----CTPVPVTMTA------TPPLPKPVNTSLSPSPALALPNLANVDLAKIS 457
               S +S+     TP+PVT  +      T PLP    +S S      LP      +   S
Sbjct: 1298 HVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLP------VTDAS 1351

Query: 458  SILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEIT 517
            S+ +  T+ +  T  S AS              +G  TP P T+ S       +S  + T
Sbjct: 1352 SVSTGHTTPLHVTDASSAS--------------TGQATPLPVTSLSS------VSTGDTT 1391

Query: 518  PESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRN 577
            P  + S  S +   + P L   +S   +    P+P ++A+S ST         +T     
Sbjct: 1392 PLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDH-------ATSLPVT 1444

Query: 578  LPSSAQP--FIPKSFNYSPNSSTSEVSS---TSASKASIGQSPGLPSTTFKLPSNSLGFT 632
            +PS+A      P     + ++ST + +S   T  S  S G +  LP T+    S     T
Sbjct: 1445 IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTG-HVT 1503

Query: 633  ATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPIL 692
              H TSP++  T      ++ +    L S ST  ++ + +      +   +G    +P+ 
Sbjct: 1504 PLHVTSPSSASTG----HATPLPVTSLSSASTGDTMPLPV---TSPSSASTGDTTPLPVT 1556

Query: 693  SSLGSSAPSESHPSDFQ-RGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMS 751
                +S+ S  H +      P+S S  +    PV D  S +      +   + SS  T  
Sbjct: 1557 D---ASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSAST-- 1611

Query: 752  LLSKIISPGSSTP---SSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGME 808
                    G +TP   + T S   G     P   ++S+ST     L   SP    S G  
Sbjct: 1612 --------GHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSP-SSASTGHA 1662

Query: 809  RPSSLMDSS 817
             P  +  +S
Sbjct: 1663 TPLPVTSTS 1671



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 117/482 (24%), Positives = 172/482 (35%), Gaps = 86/482 (17%)

Query: 349  PTMESEKSATPEPVTDNRDVEDMELSDVE----DDGSKIIVEDRKEKPAEKSAVSTSVPT 404
            P+  S    TP PVT    V    ++ +        S   V          ++   + P 
Sbjct: 3574 PSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPL 3633

Query: 405  KPTENISKASS-CTPVPVTMTA------TPPLPKPVNTSLSPSPALALPNLANVDLAKIS 457
              T+  S ++   TP+PVT  +      T PLP    +S S   A  LP      +  +S
Sbjct: 3634 LVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLP------VTSLS 3687

Query: 458  SILSSLTSVMKNTGVSPAS--RPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVE 515
            S+ +  T+ +  T  S AS    +P   T PS++++G   P P T+ S     +      
Sbjct: 3688 SVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATP--- 3744

Query: 516  ITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVP-ASEAASQSTSASPANTTVSTIK 574
              P + LS+ S   T   P     S+  +  T  PV   S A++  T+  P     S   
Sbjct: 3745 -LPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSAST 3803

Query: 575  GRNLP---SSAQPFIPKSFNYSPNSSTSEVSS--------TSASKASIGQSPGLPSTTFK 623
            G   P   +S            P + TS VS+        TS S AS G +  LP T   
Sbjct: 3804 GHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTS 3863

Query: 624  LPSNS----LGFTATHNTS-------PAAPPTEVTICQSSEVSKPKLESESTSPSLEMKI 672
              S      L  T+T + S       P   P+  +   ++ V      S ST  +  + +
Sbjct: 3864 SVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPV 3923

Query: 673  HNFLKGNPGFSGLNLNIPILSSLGSSAPSESH---PSDFQRGPTSTSIDNIDGTPVRDER 729
             N                  SSL +   +  H   PS   RG TST        PV D  
Sbjct: 3924 TN-----------------ASSLSTGHATPLHVTSPSSASRGDTST-------LPVTDAS 3959

Query: 730  SGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTP---SSTRSPPPGRDESYPRELSNSV 786
            S +      +   + SSV T          G +TP   + T S   G+    P    +SV
Sbjct: 3960 SASTGHATPLPLTSLSSVST----------GDTTPLPVTDTSSASTGQATPLPVTSLSSV 4009

Query: 787  ST 788
            ST
Sbjct: 4010 ST 4011



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 237/1148 (20%), Positives = 379/1148 (33%), Gaps = 163/1148 (14%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVED 370
            ST+     SP  SP++               G  ++   T ES+ + +  P+TD + V  
Sbjct: 619  STIHSTSTSPQESPAVSQ------------RGHTQAPQTTQESQTTRSVSPMTDTKTVTT 666

Query: 371  MELSDVED--DGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPP 428
               S        S+I+ +D     A   + +T+    PT +       T  P   TA   
Sbjct: 667  PGSSFTASGHSPSEIVPQD-----APTISAATTFAPAPTGD----GHTTQAPT--TALQA 715

Query: 429  LPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSN 488
             P   + +L PS   +L     + LA  +S++S                 +PG P     
Sbjct: 716  APSSHDATLGPSGGTSLSKTGALTLA--NSVVS-----------------TPGGPEGQWT 756

Query: 489  LTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTG 548
              S   +P  A   +H   A               A  +TQT S PA  G  +   +  G
Sbjct: 757  SASASTSPDTAAAMTHTHQA-----------ESTEASGQTQT-SEPASSGSRT---TSAG 801

Query: 549  NPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASK 608
               P+S  AS +T   P+ +   +  G     S+ P    S +     ST+E+ S SAS 
Sbjct: 802  TATPSSSGASGTT---PSGSEGISTSGETTRFSSNP----SRDSHTTQSTTELLSASASH 854

Query: 609  ASIGQSPGLPST----TFKLPSNSLGFTA------THNTSPAAPPTE-VTICQSSEVSKP 657
             +I  S G+ S+    TF  P+ S   TA      +  TSP+A P E   I + ++  + 
Sbjct: 855  GAIPVSTGMASSIVPGTFH-PTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRT 913

Query: 658  KLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAP-SESH---PSDFQRGPT 713
            +    S + SL        +    FS +    P ++S G ++P +E+H   PS   +  T
Sbjct: 914  RTSRGSDTISLAS------QATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFT 967

Query: 714  STSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPG 773
            +  I N    PV    S +      +    +SSV T       ++  SS  +   +P P 
Sbjct: 968  TALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPV 1027

Query: 774  RDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKF-----YPDTSFQ 828
             D S     S S     P  + S   +   S G   P  + D+S          P TS  
Sbjct: 1028 TDTS-----SESTGHVTPLPVTS---FSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLS 1079

Query: 829  EDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSA 888
                    + +  P +   +     A S+  +   S +T +   L      +   G  ++
Sbjct: 1080 SAS---TGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATS 1136

Query: 889  FPPSVRALLDSSEN-----CDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSN 943
             P +  + + +         D  S+S G      V      S    +P    S  +  + 
Sbjct: 1137 LPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTG 1196

Query: 944  H------NSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGH-PPTSGVEKV 996
            H         S ++TGH + P      S     H +        AA TGH  P    +  
Sbjct: 1197 HATPLLVTDTSSASTGH-ATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTS 1255

Query: 997  LASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQ 1056
             AST   TS +    +   +S    D        +    +  V+  ++T PS  +T    
Sbjct: 1256 SASTGQATSLL----VTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHAT 1311

Query: 1057 QEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGN 1116
                  + +  +   + LP ++             SAS    +  P+    S+   G   
Sbjct: 1312 PLPVTSLSSASTGDTMPLPVTSPS-----------SASTGDTTPLPVTDASSVST-GHTT 1359

Query: 1117 RGHGREASRVGWFDLS----TSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAP 1172
              H  +AS       +    TS SS   G ++   + S     +G  T          + 
Sbjct: 1360 PLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSAST 1419

Query: 1173 QFQESVGSFRSNSFNSTFEHHLP---PSPLE--HGTPFQREPVGPSS---APPVPPKDHG 1224
                 +    ++S ++     LP   PS     H TP        +S   A  +   D  
Sbjct: 1420 GHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTS 1479

Query: 1225 GIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPP----------PPP 1274
             + + D  T LP    S+  T      H   P         P P             P P
Sbjct: 1480 SVSTGDT-TPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLP 1538

Query: 1275 PPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKDHSSLLQG 1334
                 S+S G   P            H+  +P  +P  A  G    + V   D SS  +G
Sbjct: 1539 VTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPV--TDTSSASKG 1596

Query: 1335 TLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLP-----SHSLEHLGPPHGGGGGG 1389
                     P     G  T   +     +   ++  LP     S S  H  P H      
Sbjct: 1597 DTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSS 1656

Query: 1390 GSNSSSGP 1397
             S   + P
Sbjct: 1657 ASTGHATP 1664



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 205/963 (21%), Positives = 335/963 (34%), Gaps = 140/963 (14%)

Query: 396  SAVSTSVPTKPTENISKASSCTPVPV---TMTATPPLPKPVNTSLSPSPALALPNLANVD 452
            SA S +  TK TE  SKA + T   +   T+ ++P +   + T+       + P+     
Sbjct: 71   SASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNT 130

Query: 453  L---AKISSILSSLTSVMKNTGVSPASRPSPGTP-TSPSNLTSGLKTPAPATT------- 501
            L   +K  ++ +S  S + NT  +  +     TP TS  ++T+G +  +  T+       
Sbjct: 131  LMMTSKTITMTTSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQD 190

Query: 502  TSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQST 561
            TS +   +     + T ES  S L+   T +      + ++  +V+    P+ E A+ S 
Sbjct: 191  TSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSL 250

Query: 562  SASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTT 621
              S  NT++ T                      +   +  +ST ++  + G++  +P T 
Sbjct: 251  -CSVTNTSMMT----------------------SEKITVTTSTGSTLGNPGETSSVPVTG 287

Query: 622  FKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPG 681
              +P  S           +      T  Q +       +++S   +   +I+        
Sbjct: 288  SLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINT------- 340

Query: 682  FSGLNLNIPILSSLGSSAPSESHPSD------FQRGPTSTSI-DNIDGT-PVRDERSGTP 733
               LN   P+ +S   S+PS  +PS       F  G T+TS   ++  T  V  +    P
Sbjct: 341  ---LNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMP 397

Query: 734  T-QDEMMDKPTSSSVDTMSLLSKIISPGSS-----TPSSTRSPPPGRDESYPRELSNSVS 787
            T +D  +     +S+     +S I S  S+     T S+  SP      S P ++S +  
Sbjct: 398  TSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSP-----SSLPPKISTAFH 452

Query: 788  TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM 847
            T             Q S+G E      + S   F P  S    E +   E +  P S   
Sbjct: 453  T-------------QQSEGAETTGRPHERSS--FSPGVS---QEIFTLHETTTWPSSFSS 494

Query: 848  NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS 907
                  +++ L S+     T     L + +      G     P  V A+ +  E     S
Sbjct: 495  KGHTTWSQTELPSTSTGAATR----LVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSS 550

Query: 908  SSPGL-----FGAFSVRGNEPGSDRSP---SPSKNDSFFTPDSNHNSLSQSTTGHLSLPQ 959
             S  L      GA +    E G+       SPS + +     +   S S     H S   
Sbjct: 551  HSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQI 610

Query: 960  KQYPDSPHPVPHRSLFSPQNTLA-APTGH---PPTSGVEKVLASTISTTSTIEFKNMLKN 1015
               P + H   H +  SPQ + A +  GH   P T+   +   S    T T       K 
Sbjct: 611  TTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDT-------KT 663

Query: 1016 ASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLP 1075
             +   S     G +PS+  P D  ++S  T  +   T            T+  ++ L   
Sbjct: 664  VTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHT-------TQAPTTALQAA 716

Query: 1076 DSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTS- 1134
             S+ +      TLG    ++   +G        +  PG G  G    AS     D + + 
Sbjct: 717  PSSHDA-----TLGPSGGTSLSKTGALTLANSVVSTPG-GPEGQWTSASASTSPDTAAAM 770

Query: 1135 ------GSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNS 1188
                   S+  +G +  SE AS G       T   TA             GS   ++   
Sbjct: 771  THTHQAESTEASGQTQTSEPASSGSR----TTSAGTATPSSSGASGTTPSGSEGISTSGE 826

Query: 1189 TFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEA 1248
            T      PS   H T    E +  S++    P   G   S    T  P+  LS   T   
Sbjct: 827  TTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPT--LSEASTAGR 884

Query: 1249 ALAHAAPPPP---PGEHSGIP--FPTPPPPPPPGEHSSSGGSGVP--FSTPPPPPPPVDH 1301
                ++P  P   P E + I     T       G  + S  S     FST PP PP +  
Sbjct: 885  PTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITS 944

Query: 1302 SGV 1304
            +G+
Sbjct: 945  TGL 947



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 195/939 (20%), Positives = 320/939 (34%), Gaps = 124/939 (13%)

Query: 407  TENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSV 466
            TE+     S T  PVT T +         +L      A    +N D++      SS    
Sbjct: 30   TEDTLITGSKTAAPVTSTGS------TTATLEGQSTAASSRTSNQDISA-----SSQNHQ 78

Query: 467  MKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALS 526
             K+T  +  ++    T    S L S   +P+        P   + +    +  + L   S
Sbjct: 79   TKSTETTSKAQTDTLTQMMTSTLFS---SPSVHNVMETAPPDEMTTSFPSSVTNTLMMTS 135

Query: 527  KTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFI 586
            KT T        +++   S  GN    S A ++S++  P  + VS   G+   S    + 
Sbjct: 136  KTIT--------MTTSTDSTLGNTEETSTAGTESST--PVTSAVSITAGQEGQSRTTSWR 185

Query: 587  PKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPS-----NSLGFTATHNTSPAA 641
                + S +S      ST  ++ S  Q+  L   T   PS     +++  T +  TSP+ 
Sbjct: 186  TSIQDTSASSQNHWTRSTQTTRES--QTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSG 243

Query: 642  PPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPS 701
                 ++C  +  S    E  + + S    +     GNPG +    ++P+    GS  P 
Sbjct: 244  ETATSSLCSVTNTSMMTSEKITVTTSTGSTL-----GNPGETS---SVPV---TGSLMPV 292

Query: 702  ESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGS 761
             S            + D    +P    R+ T           + SV+T + +S+I +  +
Sbjct: 293  TS--------AALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVET-TRVSQINTLNT 343

Query: 762  STPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDS---SQ 818
             TP +T +            + +S S + P G  S+  +         PSS+ ++   + 
Sbjct: 344  LTPVTTST------------VLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTS 391

Query: 819  EKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLS---DTTEYQPILSS 875
            + F   TS   D    + E +    S  ++       +I  S  LS     +   P +S+
Sbjct: 392  KVFRMPTS--RDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKIST 449

Query: 876  YSHRAQEFGVKSAFPPSVRALLDS--SENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSK 933
              H  Q  G ++   P  R+      S+    L  +     +FS +G+   S ++  PS 
Sbjct: 450  AFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWS-QTELPST 508

Query: 934  NDSFFTPDSNHNSLSQSTTGHL-SLPQK----QYPDSPHPVPHRSLFSPQNTLAAP---- 984
            +    T     N  S  T G +  +P K      P  P      S   P+ T A      
Sbjct: 509  STGAATRLVTGNP-STGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQW 567

Query: 985  TGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSL-SN 1043
            T    T+G   + + + S T  I+      + S  P  D+H  Q  +    ++  ++ S 
Sbjct: 568  TQETGTTGEALLSSPSYSVTQMIK---TATSPSSSPMLDRHTSQQITTAPSTNHSTIHST 624

Query: 1044 LTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIE----TLGYHSASNRRMS 1099
             T P  +    Q+        T+ S +   +   T+ K         T   HS S     
Sbjct: 625  STSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQ 684

Query: 1100 GEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDN--GPSSASELASLG----- 1152
              P  +  +   P     GH  +A       L  + SS D   GPS  + L+  G     
Sbjct: 685  DAPTISAATTFAPAPTGDGHTTQAPTTA---LQAAPSSHDATLGPSGGTSLSKTGALTLA 741

Query: 1153 -------GGGSGGLT--GFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGT 1203
                   GG  G  T     T+P    A        S  ++    T E   P S     T
Sbjct: 742  NSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSE---PASSGSRTT 798

Query: 1204 PFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKE-------AALAHAAPP 1256
                     S A    P    GI +    T   S    +  T +       A+ +H A P
Sbjct: 799  SAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIP 858

Query: 1257 PPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPP 1295
               G  S I    P    P    +S+ G     S+P  P
Sbjct: 859  VSTGMASSI---VPGTFHPTLSEASTAGRPTGQSSPTSP 894



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 84/417 (20%), Positives = 151/417 (36%), Gaps = 73/417 (17%)

Query: 392 PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANV 451
           P++ SA+      +P E  + +S  T +P T  A         T  +    L+ P+ +  
Sbjct: 533 PSKVSAIG-----EPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVT 587

Query: 452 DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPA------------ 499
            + K ++  SS   + ++T     + PS    T  S  TS  ++PA +            
Sbjct: 588 QMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQ 647

Query: 500 ---TTTSHNPLANILSKVEITPESILSAL----SKTQTQSAPALQGLSSLLQSVTGNPVP 552
              TT S +P+ +  +K   TP S  +A     S+   Q AP +   ++   + TG+   
Sbjct: 648 ESQTTRSVSPMTD--TKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDG-H 704

Query: 553 ASEAASQSTSASPAN--TTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKAS 610
            ++A + +  A+P++   T+    G +L  +    +  S   +P     + +S SAS + 
Sbjct: 705 TTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTS- 763

Query: 611 IGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEM 670
                         P  +   T TH              +S+E S     SE        
Sbjct: 764 --------------PDTAAAMTHTHQA------------ESTEASGQTQTSE-------- 789

Query: 671 KIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERS 730
                    P  SG        ++  SS  S + PS  +   TS         P RD  +
Sbjct: 790 ---------PASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHT 840

Query: 731 GTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS 787
              T + +    +  ++   + ++  I PG+  P+ + +   GR        S S S
Sbjct: 841 TQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSAS 897


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
            tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 83/266 (31%), Positives = 97/266 (36%), Gaps = 49/266 (18%)

Query: 1152 GGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSP----LEHGTPFQR 1207
            GGGG GGL  F++ P         ++ G        S  +  +PP P     +   P Q 
Sbjct: 21   GGGGRGGLHDFRSPP---PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQP 77

Query: 1208 EPVGP-------------SSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
             P  P                PP PP+D         P   P V  + P +  A    A 
Sbjct: 78   PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP--PAT 135

Query: 1255 PPP---PPGEHSGIPFPTPPPP----PPPGEHSSSGGSGVPFSTPP----PPPPPVDHSG 1303
            PP    PPG   G P PTPPP     PP     +   SGVP +TPP    PPPPP     
Sbjct: 136  PPTSGAPPGSGPG-PTPTPPPAVTSAPPGAPPPTPPSSGVP-TTPPQAGGPPPPPA---- 189

Query: 1304 VVPFPAP-PLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGL 1362
             VP P P P    G  G     PK     + G      G  PG    GG  +    G G 
Sbjct: 190  AVPGPGPGPKQGPGPGG-----PK--GGKMPGGPKPGGG--PGLSTPGGHPKPPHRGGGE 240

Query: 1363 SRVRESLTLPSHSLEHLGPPHGGGGG 1388
             R       P H   H GPP GG GG
Sbjct: 241  PRGGRQHHPPYHQQHHQGPPPGGPGG 266


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 172/825 (20%), Positives = 279/825 (33%), Gaps = 107/825 (12%)

Query: 330  SPTGSESPFQGMGGEESQSPTM-------ESEKSATPEPVTDNRDVEDMELSDVEDDGSK 382
            +P GS SP   M G E + PT         SE  + P+P   +  +    L+        
Sbjct: 2961 TPEGSASP--SMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFS 3018

Query: 383  IIVEDRKEKPAEKSAVSTSVPTK---PTENISKASSCTPVPVTMTATPPLPKPVNTS--- 436
                 R    +   ++ST   T    PT + S+ +S    P +M   P +   + TS   
Sbjct: 3019 TGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGP-SMARQPNILVHLQTSALT 3077

Query: 437  LSPSPALALPNLANVDLAKISSILSS--LTSVMKNTGVSPASRPSPGTPTSPSNLTSGLK 494
            LSP+  L +      +L    +I      T+  +    +P+  P+   P S     +  +
Sbjct: 3078 LSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARR 3137

Query: 495  TPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPAS 554
              +P T  S   +    S VE T  ++++ +      S+ A QG S+        P PA 
Sbjct: 3138 KSSPETWASSISVPAKTSLVETTDGTLVTTIK----MSSQAAQGNSTW-------PAPAE 3186

Query: 555  EAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQS 614
            E  S     SP +  +ST     + SS +P I      +  +S  +   T+    +  + 
Sbjct: 3187 ETGSSPAGTSPGSPEMSTTL--KIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEP 3244

Query: 615  PGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHN 674
              L ST     S S+    T  TSP   PTE  +           E  S SPS      N
Sbjct: 3245 VTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLA---------TERVSLSPSPPEAWTN 3295

Query: 675  FLKGNPG--------FSGLNLNIPILSSL-GSSAPSESHPSDFQRGPTSTSIDNIDGTPV 725
               G PG         S ++L  P   S+ G+   S         G   +      G   
Sbjct: 3296 LYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTT 3355

Query: 726  RDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPP---GRDESYPREL 782
             D      T   +++ P +S     SL  K      +  S+T  P      +  +  ++ 
Sbjct: 3356 GDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQT 3415

Query: 783  SNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPP 842
            S SV         S S +   + G +             Y  ++ Q              
Sbjct: 3416 SRSVDE----AYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTS-------LVSL 3464

Query: 843  PSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSEN 902
            PS    +      S  K+S  S  T   P +   + RA    VKS   P+   L  +S  
Sbjct: 3465 PSGDQGITSLTNPSGGKTSSASSVT--SPSIGLETLRANVSAVKSDIAPTAGHLSQTSSP 3522

Query: 903  CD------RLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLS 956
             +        + +PG+    +  G    S  +P+P               +  ST     
Sbjct: 3523 AEVSILDVTTAPTPGISTTITTMGTNSISTTTPNP--------------EVGMSTMDSTP 3568

Query: 957  LPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNA 1016
              +++   + HP    S +S      + T    TS ++  +A +  T ST+   + L ++
Sbjct: 3569 ATERRTTSTEHP----STWSSTAASDSWTVTDMTSNLK--VARSPGTISTMHTTSFLASS 3622

Query: 1017 SRKPSDDKHFGQAPSKGT-----PSDGVSLSNLTQPSLTATDQQQQEEHYRIET-----R 1066
            +   S     G+    GT      SD  ++   T  S              I T     R
Sbjct: 3623 TELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQR 3682

Query: 1067 VSSSCLDL------PDSTEEKGAPIETLGYHSASNRRMSGEPIQT 1105
            +S S  D+      P STE +  P+  +    AS +     P+ T
Sbjct: 3683 MSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLST 3727



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 182/894 (20%), Positives = 314/894 (35%), Gaps = 95/894 (10%)

Query: 457  SSILSSLTSVMKNTGVSPASRPSPGTPTSP-----SNLTSGLKTPAPATTTSHNPLANIL 511
            +S  SSLT  +  T + PA+    G  TS      S LTSGL        TS  P+ N  
Sbjct: 4450 TSYPSSLTPFLVTT-IPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSP 4508

Query: 512  SKVEITPESILSALSKT--------QTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSA 563
              +      IL+ L+ T            A    G +S    +      +SE ++ ++  
Sbjct: 4509 QNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSEPSTATSPM 4568

Query: 564  SPANTTVSTIKGRNLPSS------AQPFIPKSFNYSPNSSTSEVSSTSASK---ASIGQS 614
             PA++    +   ++P S       +P    +     NS+  E++ST+ S    +++   
Sbjct: 4569 VPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVG 4628

Query: 615  PGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHN 674
                +T  ++PS    F  T   S   P  ++    SS +S         SP + +  H 
Sbjct: 4629 AITEATKMEVPSFDATFIPTPAQSTKFP--DIFSVASSRLSN--------SPPMTISTH- 4677

Query: 675  FLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD-ERSGTP 733
                  G SG    IP+     +   S   PS    G   + I       V+D  ++  P
Sbjct: 4678 MTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPP 4737

Query: 734  TQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFG 793
             QDE     + + V   +L           PSS    P     S P  +S+ +++     
Sbjct: 4738 FQDEASSPSSQAPVLVTTL-----------PSSVAFTPQWHSTSSPVSMSSVLTSSLVKT 4786

Query: 794  LGS-ESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYS--GPPPSAM---- 846
             G  ++  +  +   +  S+ +D         T  +      +   +  G   SA     
Sbjct: 4787 AGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHS 4846

Query: 847  -MNLEKKPAKSI---LKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSEN 902
             ++   +P+K     + +S + DTT  + I  S      E    S+  P +R    S E 
Sbjct: 4847 TVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEI 4906

Query: 903  CDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQST-------TGHL 955
                 +S   +   +    E  S    + S + SF  PD +  SL  ST       T  +
Sbjct: 4907 TSSTETSTVPYKELTGATTEV-SRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPI 4965

Query: 956  SLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLA---STISTTSTIEFKNM 1012
                 +   +    PH +      T+  P+   P +G+   +    S +  T+ +     
Sbjct: 4966 MTESAEITITTQTGPHGATSQDTFTM-DPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQ 5024

Query: 1013 LKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCL 1072
              + +  PS DK         +PS  +S   +T PSL ++   + +    + + ++S  +
Sbjct: 5025 DVSWTSPPSVDK-------TSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLV 5077

Query: 1073 DLPDSTEEKGAPIETL--GYHSASNRRMSGE----------PIQTVESIRVPGKGNRGHG 1120
             + D    +  P+ +    + S S++ ++            P    E   V    N GH 
Sbjct: 5078 KITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKA-NNSGHE 5136

Query: 1121 REASRVGWFDL--STSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESV 1178
              +  +   +   +T+           +   S+   GS   T  K  P     P+ +E+ 
Sbjct: 5137 SHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETS 5196

Query: 1179 GSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSV 1238
             S + +SF +     L   P    T      V  SS    P  D   +        +P V
Sbjct: 5197 TS-QESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRV 5255

Query: 1239 DLSNPFTK--EAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFS 1290
              S+  TK  E  +   A PP    HS +P  T       G HS+    G P+S
Sbjct: 5256 FTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTV-TQGFPYS 5308



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 205/1042 (19%), Positives = 356/1042 (34%), Gaps = 128/1042 (12%)

Query: 260   QVKNGPSLTEALENAGIFYE-AQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEE 318
             Q K+  SLT  L    I  E +   E   V ++  T A    +  + +   ++++P P +
Sbjct: 9279  QTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQ 9338

Query: 319   SPVPS------------PSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNR 366
             S + S            P     S   + +P  G  G  SQ        S    P T + 
Sbjct: 9339  STMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSA 9398

Query: 367   DVEDMELSDVEDDGSK----------IIVEDRKEKPAEKSAVSTSVPTKPTENISKASSC 416
               +    S V    S+          + VE      +  S+ S + P+      S +S  
Sbjct: 9399  TTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHS 9458

Query: 417   TPVPVTMTATPPLPKP---VNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVS 473
             +PVPVT   T  + K    ++ SL P    A     N+++    S+ +S  +    T   
Sbjct: 9459  SPVPVTSLFTSIMMKATDMLDASLEPETTSA----PNMNITSDESLAASKATT--ETEAI 9512

Query: 474   PASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSA 533
                  +  +    ++ T  L + +P  +     ++ +++   I    + + +  +   + 
Sbjct: 9513  HVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITR 9572

Query: 534   PALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYS 593
               ++ +SSL       P       SQ  ++S   +TV                       
Sbjct: 9573  IEIESMSSL------TPGLRETRTSQDITSSTETSTV-------------------LYKM 9607

Query: 594   PNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSE 653
             P+ +T EVS T    +S    PG   +T  L  +    T    +       E+TI   + 
Sbjct: 9608  PSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQTG 9667

Query: 654   VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
              S   L +   +  L   +  FL G        L+   +++L S  P     +  +   T
Sbjct: 9668  YS---LATSQVTLPLGTSM-TFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVET 9723

Query: 714   STSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLL------SKIISPGSSTPSST 767
             + S  ++   P+    S  P    ++D   SS +   SL+      +  +   SS P ++
Sbjct: 9724  TRSSSSLTSLPLTTSLS--PVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTS 9781

Query: 768   RSP---PPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSS-LMDSSQEKFYP 823
              SP       +     E+        P    + +  +  S   E  SS L DS      P
Sbjct: 9782  SSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIP 9841

Query: 824   DTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEF 883
                     D      S P  S    +  +P  S+    + + T+E    ++  S  A  +
Sbjct: 9842  SMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETS--AVLY 9899

Query: 884   GVKSAFPPSVRALLDSSEN------CDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSF 937
             GV ++    V      S N       D+ + SP +      R     S    S S   + 
Sbjct: 9900  GVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITR---LSSSSMMSESTQMTI 9956

Query: 938   FTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVL 997
              T  S+  + +QST   L+        +   VP R L S   TL + +   P+      +
Sbjct: 9957  TTQKSSPGATAQSTL-TLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFV 10015

Query: 998   ASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQ 1057
               T S++S +         +  PS      Q+     PS   S+++L  P +  T     
Sbjct: 10016 EKTSSSSSLLSLP-----VTTSPSVSSTLPQS----IPSSSFSVTSLLTPGMVKTTDTST 10066

Query: 1058  EEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNR 1117
             E    +   +S             G  +E L   +AS      E I    S+ V   G  
Sbjct: 10067 EPGTSLSPNLS-------------GTSVEIL---AASEVTTDTEKIHPSSSMAVTNVGTT 10110

Query: 1118  GHGREASRVGWFDLSTSGSSFDNG-PSSASELA-SLGGGGSGGLTGFKTAPYKERAPQFQ 1175
               G E           S +++  G PSS +E + S     +   TGF+  P+      F+
Sbjct: 10111 SSGHELYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFR 10170

Query: 1176  ESVGSFRSNSFNSTFEHHLPPSP----LEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDA 1231
             ++  S  ++S   T   + P SP    L   +         +S+P  PP           
Sbjct: 10171 KTNMSLDTSSVTPT---NTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQ-------- 10219

Query: 1232  PTHLPSVDLSNPFTKEAALAHA 1253
              T +P VD+  PF    ++  +
Sbjct: 10220 YTEIP-VDIITPFNASPSITES 10240



 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 197/941 (20%), Positives = 338/941 (35%), Gaps = 125/941 (13%)

Query: 346  SQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGS-KIIVEDRKEKPAEKSAVSTSVPT 404
            S S  + +  +++   VT    +    +S +    S  +   DR + P   +  +T+   
Sbjct: 2369 SSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSP 2428

Query: 405  KPTENISKASSCTPVPVTMTATPP--LPKPVNTSLS----PSPALALPNLANVDLAKISS 458
              + N       + V  T +  PP  +  PV TS +      P      + + D A   +
Sbjct: 2429 SVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGEN 2488

Query: 459  ILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTS----GLKTPAPATTTSHNPLANILSKV 514
              SS + V         S P+PGT TS  + T     G    +PA   +H+ LA+ +   
Sbjct: 2489 PTSSNSVV--------TSVPAPGTWTSVGSTTDLPAMGFLKTSPAGE-AHSLLASTIEPA 2539

Query: 515  E-ITPESILSALSKTQTQSAPAL--QGLSSLLQSVTGNPVPASEAASQSTSASPAN---- 567
               TP    + ++ +   S  +L     S  + S    P   +  A+  TSA+P +    
Sbjct: 2540 TAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESLLVV 2599

Query: 568  --TTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLP 625
              T+ +T+  + L +    F   S   S   ST  +S  S     +  +P +P T  + P
Sbjct: 2600 TETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTL-LPDTPAIPLTATE-P 2657

Query: 626  SNSLG--------FTATHNTSPAAPPTEVTICQSSE-----------------------V 654
            ++SL          T   ++    P T +T+ ++S                        V
Sbjct: 2658 TSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGV 2717

Query: 655  SKPKLESESTSPSLEMKIHNFL-KGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
            ++  L   STSPS  +   N   +G+   +   L      SL  S  SE+  +      +
Sbjct: 2718 TESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSENSETT-ALVDS 2776

Query: 714  STSIDNIDGTPVRDERSGTPTQDEMMDKPT-SSSVDTMSLLSKIISPGSSTPSSTRSPPP 772
            S  ++     P+     G  +   +    T S+   T S L   ++PG  T  S      
Sbjct: 2777 SAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMS------ 2830

Query: 773  GRDESYPRELSNSVSTYRPFGLGSESPYKQPS--DGMERPSSLMDSSQEKFYPDTSFQED 830
               E     L+ + ST  P G+    P K  S   G+  P S   S  + F   T+    
Sbjct: 2831 ---EITTNRLTATQST-APKGI----PVKPTSAESGLLTPVSASSSPSKAFASLTTAPPT 2882

Query: 831  ----EDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYS-HRAQEFGV 885
                +    FE+S  P     +L+ K A        L+   +     +S S  ++ E   
Sbjct: 2883 WGIPQSTLTFEFSEVP-----SLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNP 2937

Query: 886  KSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKND------SFFT 939
            ++    S +A+  SS      + +P    + S+ G+EP   R P+    D      S   
Sbjct: 2938 RARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEP---RVPTSGTGDPRYASESMSY 2994

Query: 940  PDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLAS 999
            PD +  S + ++T   SL  K            +LFS      + +   P S   +   S
Sbjct: 2995 PDPSKASSAMTST---SLASKL----------TTLFSTGQAARSGSSSSPISLSTEKETS 3041

Query: 1000 TISTTSTIEFKNML---KNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQ 1056
             +S T++   K  L    + +R+P+   H   +    +P+  +++S    P LT++    
Sbjct: 3042 FLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIA 3101

Query: 1057 QEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGN 1116
            +EE    ET+  +     P  T     P+ +    +    R    P     SI VP K +
Sbjct: 3102 EEEGTTAETQTLTF---TPSETPTSLLPVSS---PTEPTARRKSSPETWASSISVPAKTS 3155

Query: 1117 RGHGREASRVGWFDLSTSGSSFDN-GPSSASELASLGGGGSGGLTGFKTA--PYKERAPQ 1173
                 + + V    +S+  +  ++  P+ A E  S   G S G     T       + P 
Sbjct: 3156 LVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPS 3215

Query: 1174 FQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSS 1214
                + S   NS   T E  +P          Q   +G  S
Sbjct: 3216 ISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGS 3256



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 104/464 (22%), Positives = 176/464 (37%), Gaps = 48/464 (10%)

Query: 352  ESEKSATPEPVTDNRDVEDMELSDVEDDGSKII-------VEDRKEKPAEKSAVSTSVPT 404
            E  + +T  P+T +    D+E        +K +       +     +    SA   S   
Sbjct: 1741 EGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTAL 1800

Query: 405  KPTENISKASSCTPVPVTMTATPPLPKPV-NTSLSPSPALALPNLAN----VDLAK---I 456
              TEN  K           TA+  LP P  +  ++P  +L L N  N    +DL+     
Sbjct: 1801 GSTENTGKEK-------LRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHT 1853

Query: 457  SSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEI 516
            SS  +  T    NTGV+ ASR   G+ TS  +L+ G  T    T+ ++   + + S +  
Sbjct: 1854 SSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNST---HTSMTYTEKSEVSSSIHP 1910

Query: 517  TPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASP----ANTTVST 572
             PE+       T T S P  + +S  L     + +P  E  S   ++ P    A  T S 
Sbjct: 1911 RPETSAPGAETTLT-STPGNRAISLTLPF---SSIPVEEVISTGITSGPDINSAPMTHSP 1966

Query: 573  IKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFT 632
            I    +  ++   I +S       S+ +VS  + S   +       S T +   +S   T
Sbjct: 1967 ITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSST 2026

Query: 633  ATHNTSPAAPPTEVTICQSSEV---------SKPKLESESTSPSLEMKIHNFLKGNPGFS 683
            ++  +S +    + TI + + +         S P     STS S  +   +    NP  S
Sbjct: 2027 SSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNP--S 2084

Query: 684  GLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPT 743
                  P+ S+  +SA  + +P     GP +T+   ++     D  S T   +  +    
Sbjct: 2085 STTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLN----TDASSVTGLSETPVGASI 2140

Query: 744  SSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS 787
            SS V     ++        T  ST +P  G   S   +L+ ++S
Sbjct: 2141 SSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTIS 2184



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 180/836 (21%), Positives = 289/836 (34%), Gaps = 129/836 (15%)

Query: 294  TFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMG-GEESQSPTME 352
            T A  V           S L D E++   +P MD  S  G  +    M    E+     E
Sbjct: 6886 TAATNVETTSSGHGSQSSVLADSEKTKATAP-MDTTSTMGHTTVSTSMSVSSETTKIKRE 6944

Query: 353  SEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISK 412
            S  S TP      R+    + +    D S ++ E      AE S          TE  S 
Sbjct: 6945 STYSLTP----GLRETSISQNASFSTDTSIVLSEVPTGTTAEVSR---------TEVTSS 6991

Query: 413  ASSCTPVPVTMTATPPLPKPVNTSLSPSP-----------------------ALALPNLA 449
              +  P P   T  P +     T L  SP                        L L    
Sbjct: 6992 GRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTST 7051

Query: 450  NVDLAKISSIL------SSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPA------ 497
                AK  S L      S +T++M + G    S  S  +  +PS+L S L  PA      
Sbjct: 7052 TKSQAKTHSTLTQRFPHSEMTTLM-SRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPP 7110

Query: 498  -----PAT-TTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPV 551
                 P T ++S  P+ ++L+   +T   +L    +  T S P L   S   +  TG   
Sbjct: 7111 ISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSD-ERLTTGKDT 7169

Query: 552  PASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS---- 607
              +EA   ST+ + +N  + +  G   PSSA      S   SP   TS    T+ +    
Sbjct: 7170 TNTEAVHPSTNTAASNVEIPS-SGHESPSSALADSETSKATSPMFITSTQEDTTVAISTP 7228

Query: 608  ---KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESEST 664
               + S  Q   + S + KL         +     +A  +EV+I  ++E+S+ ++ S S 
Sbjct: 7229 HFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSR 7288

Query: 665  SPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTP 724
            + S+     + +      +   +  P    L  S+           G TS S   +D   
Sbjct: 7289 T-SISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLD--- 7344

Query: 725  VRDERSGTP----TQDEMMDKPTSSSVDTM-SLLSKIISPGSSTPSSTRSPPPGRDESYP 779
                 S TP    T   M  +   S + T+ S  +  +   SS P    SPP  +     
Sbjct: 7345 ----TSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSA 7400

Query: 780  RELSNSVSTYRPFGLGSESPYKQP--SDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFE 837
                + VS+  P    S S       + G  + + ++D+S E   P+T            
Sbjct: 7401 MISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAE---PET------------ 7445

Query: 838  YSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALL 897
             S PP  +  ++E      IL +S++  TT+ + I    +    + G  S+   S  ++L
Sbjct: 7446 -SSPPSLSSTSVE------ILATSEV--TTDTEKIHPFSNTAVTKVGTSSSGHESPSSVL 7496

Query: 898  DSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSL 957
              SE     S+     G  S+ G+   S  +P+           SN   +       L+ 
Sbjct: 7497 PDSETTKATSA----MGTISIMGDTSVSTLTPAL----------SNTRKIQSEPASSLTT 7542

Query: 958  PQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNAS 1017
              ++   S       SL +  NT+ +      T+ V +  A + S TS      M     
Sbjct: 7543 RLRETSTS----EETSLATEANTVLSKVSTGATTEVSRTEAISFSRTS------MSGPEQ 7592

Query: 1018 RKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLD 1073
               S D   G  P     S     + +T  + T   +   E    + T  + S ++
Sbjct: 7593 STMSQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVE 7648



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 120/464 (25%), Positives = 172/464 (37%), Gaps = 81/464 (17%)

Query: 408  ENISKASSCTPVPVTMTATP---PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLT 464
            E  S +SS  P P  MT+ P    LPK ++T+ SP  +L  P+L                
Sbjct: 6797 EKTSFSSSLMPSPA-MTSPPVSSTLPKTIHTTPSPMTSLLTPSL---------------- 6839

Query: 465  SVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATT---TSHNPLANILSKVEITPE-- 519
             VM    +  +  P+  +P + S+ +  + T    TT     H   +   + VE T    
Sbjct: 6840 -VMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGH 6898

Query: 520  -SILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNL 578
             S  S L+ ++   A A    +S +   T   V  S + S  T+     +T S   G   
Sbjct: 6899 GSQSSVLADSEKTKATAPMDTTSTMGHTT---VSTSMSVSSETTKIKRESTYSLTPGLRE 6955

Query: 579  PSSAQPFIPKSFNYS--------PNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLG 630
             S +Q     SF+          P  +T+EVS T  + +     PG PS +  LP  S  
Sbjct: 6956 TSISQ---NASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPG-PSQSTVLPEISTR 7011

Query: 631  FTATHNTSPA-APPTEVTI----CQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGL 685
                   SP      E+TI      S   S+  L  ++++   + K H+ L      S  
Sbjct: 7012 TMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHS-- 7069

Query: 686  NLNIPILSSLG------SSAPSESHPSDFQ---RGPTSTSIDNIDGT-PVRDERSGTPTQ 735
               +  L S G       S+PS  +PS        P +TS   I  T PV    S  P  
Sbjct: 7070 --EMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVT 7127

Query: 736  DEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVST-----YR 790
              +    TSS V T  +L        ++P    S PP    +    L+    T       
Sbjct: 7128 SLL----TSSPVTTTDML-------HTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVH 7176

Query: 791  PFGLGSESPYKQPSDGMERPSS-LMDSSQEKFYPD---TSFQED 830
            P    + S  + PS G E PSS L DS   K       TS QED
Sbjct: 7177 PSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQED 7220



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 116/490 (23%), Positives = 179/490 (36%), Gaps = 89/490 (18%)

Query: 390  EKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLA 449
            E+    SA  T+ P   T + ++ S+ +    T   T  +     T+  PS + +  +L 
Sbjct: 2315 ERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLI 2374

Query: 450  NVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHN---- 505
            N      +SI SS   V K   +SP S       +SPS L S  +   P +TT  N    
Sbjct: 2375 N------TSIASSTMDVTKTASISPTSISGMTASSSPS-LFSSDRPQVPTSTTETNTATS 2427

Query: 506  -----------------------PLANILSKVEIT--------PESILSALSKTQTQSAP 534
                                   P   I   VE +        P    S +  T T S  
Sbjct: 2428 PSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGE 2487

Query: 535  ALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSP 594
                 +S++ SV   P P +  +  ST+  PA   + T       S     I  +  ++P
Sbjct: 2488 NPTSSNSVVTSV---PAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTP 2544

Query: 595  ---------NSSTSEVS--STSASKASIGQSPGLPST--------TFKLPSNSLGFTATH 635
                     +S+TSE S  +TS SKA I  SP  P+T        T   P + L  T T 
Sbjct: 2545 HLSAAVVTGSSATSEASLLTTSESKA-IHSSPQTPTTPTSGANWETSATPESLLVVTETS 2603

Query: 636  NTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSL 695
            +T+  +          S VS P  +  ST           L   P        IP    L
Sbjct: 2604 DTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPA-------IP----L 2652

Query: 696  GSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD--ERSGTPTQDEMMDKPTSS------SV 747
             ++ P+ S  + F   P  T   +  GT        S T   D ++ K  S+       +
Sbjct: 2653 TATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGI 2712

Query: 748  DTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGM 807
                +    + P S++PS   +P   R+ +Y   ++ ++ST  P G      + Q S+  
Sbjct: 2713 TIQGVTESPLHPSSTSPSKIVAP---RNTTYEGSITVALSTL-PAGTTGSLVFSQSSENS 2768

Query: 808  ERPSSLMDSS 817
            E  ++L+DSS
Sbjct: 2769 E-TTALVDSS 2777



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 165/775 (21%), Positives = 274/775 (35%), Gaps = 132/775 (17%)

Query: 400  TSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSI 459
            TS  TK +  +SK  +     ++      +P P  +++SP       +   V     S +
Sbjct: 7842 TSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPD-----ISTRTVSWFSTSPV 7896

Query: 460  LSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTT---SHNPLANILSKVEI 516
            ++    +  NT  SP    + GT T  ++ T+ L T   +T +   SH+ ++ ++ +   
Sbjct: 7897 MTESAEITMNTHTSPLGATTQGTSTLDTSSTTSL-TMTHSTISQGFSHSQMSTLMRR--- 7952

Query: 517  TPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGR 576
             PE +         ++ P+   +SS     T +P P S    +S S+SP   T     G 
Sbjct: 7953 GPEDVSWMSPPLLEKTRPSFSLMSS---PATTSPSPVSSTLPESISSSPLPVTSLLTSG- 8008

Query: 577  NLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHN 636
                     + K+ +    SS    +S +           L ST+ ++ + S   T T  
Sbjct: 8009 ---------LAKTTDMLHKSSEPVTNSPA----------NLSSTSVEILATSEVTTDTEK 8049

Query: 637  TSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLG 696
            T P++  T   +  SS         ESTS         F+  +   S +   + I S++ 
Sbjct: 8050 THPSSNRTVTDVGTSSS------GHESTS---------FVLADSQTSKVTSPMVITSTME 8094

Query: 697  SSAPSESHPSDF-----QRGPTST------SIDNIDGTPVRDER----SGTP---TQDEM 738
             ++ S S P  F     Q  PTS+         + +GT +  E     SG P   T +  
Sbjct: 8095 DTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVS 8154

Query: 739  MDKPTSSSVDTMSLLSKI-ISPGSSTPSSTRSP------------------PPGRDESYP 779
              + TSSS  ++S  +++ +SP +ST + TR P                  PPG   S P
Sbjct: 8155 RTEVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPG---STP 8211

Query: 780  RELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYS 839
                    +  P  + + S   Q     E  + +  S  +  +P  S  E+        S
Sbjct: 8212 ESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLS 8271

Query: 840  -----GPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVR 894
                  P P +   +E  P+ S+  +S L+            S         +    S  
Sbjct: 8272 LPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHE 8331

Query: 895  ALLDSSENCDRLSSSPGLFGAF-----SVRGNEPG----SDRSPSPSKNDSFFTPDSNHN 945
             L    +  D     P    A      S+ G+E      SD     + +    T      
Sbjct: 8332 RLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGET 8391

Query: 946  SLSQSTTGHLSLPQKQY-PDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTT 1004
            S+S ST+      + Q  P S      R   S +   +A  G    S V     + +S T
Sbjct: 8392 SVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRT 8451

Query: 1005 STIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIE 1064
              I        +SR  S        P + T S  +S   +T+ S +    +  E    IE
Sbjct: 8452 EVI--------SSRGTS-----MSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIE 8498

Query: 1065 TRVSSSCLDLPDSTEEKGAPIET------LGYHSASNRRMSGEPIQTVESIRVPG 1113
            T         P +T E    ++T       G HS ++   S   + T+ S R PG
Sbjct: 8499 T-------GSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMS-RTPG 8545



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 139/641 (21%), Positives = 235/641 (36%), Gaps = 109/641 (17%)

Query: 396   SAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAK 455
             SA   +VP  P E+ + AS  T   VT T  P        + S S     P++A    A+
Sbjct: 11331 SATFPTVPESPHESEATASWVTHPAVTSTTVPR----TTPNYSHSEPDTTPSIATSPGAE 11386

Query: 456   ISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVE 515
              +S   ++T       +  +   S GT TS +  T  L +  P TTTS            
Sbjct: 11387 ATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTS------------ 11434

Query: 516   ITPESILSALSKTQTQSA----PALQGLSSLLQSV---TGNPVPASEAASQSTSASPANT 568
                       S+T T SA    P   G S +L S+   +G     +      T   P  T
Sbjct: 11435 ------FITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETT 11488

Query: 569   TVSTIKGRNLPSSAQPFIPKS---FNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLP 625
              +  I     P+     +P++   F++S + +T  V+ TS    +   S  + +TT    
Sbjct: 11489 AIQLIH----PAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEA---SSAVSTTTISPD 11541

Query: 626   SNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGL 685
              + L  +   ++      T  T+      S+   E E+T+  L          +P  +  
Sbjct: 11542 MSDLVTSLVPSSGTDTSTTFPTL------SETPYEPETTATWLT---------HPAETS- 11585

Query: 686   NLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSS 745
                    +++  + P+ SH     RG  S +  ++  +P  D RSG PT       P+  
Sbjct: 11586 -------TTVSGTIPNFSH-----RG--SDTAPSMVTSPGVDTRSGVPT---TTIPPSIP 11628

Query: 746   SVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSD 805
              V T  + S   +  +ST   T +P PG  E      + + S   P   G+++ +  P  
Sbjct: 11629 GVVTSQVTSS--ATDTSTAIPTLTPSPGEPE------TTASSATHP---GTQTGFTVPIR 11677

Query: 806   GMERPSSLMD--SSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKL 863
              +  PSS  D  +S     P TS         F +S P  + +M    +   S   S+ L
Sbjct: 11678 TV--PSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEAS---SAVL 11732

Query: 864   SDTTEYQPILSSYSHRAQEFGVKSAFP--------PSVRALLDSSENCDRLSSSPG---- 911
             +  +   P + +    +      +  P        P   ALL +    +   + P     
Sbjct: 11733 TTISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVF 11792

Query: 912   -----LFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSP 966
                     + ++R     S   P+ + +  F    +  + +  S T    +  K  P S 
Sbjct: 11793 PQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLST 11852

Query: 967   HPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTI 1007
             HP    S   P +TL+   G   T+G+    +S  ++TST+
Sbjct: 11853 HPGTETSTMIPTSTLS--LGLLETTGLLATSSSAETSTSTL 11891



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 90/409 (22%), Positives = 160/409 (39%), Gaps = 67/409 (16%)

Query: 392   PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANV 451
             PAE    +T VP + T   S + S T +PV +T+  P      ++ + SP ++       
Sbjct: 11495 PAE---TNTMVP-RTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMS------- 11543

Query: 452   DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANIL 511
             DL  ++S++ S       T  S        TP  P    + L  PA  +TT    + N  
Sbjct: 11544 DL--VTSLVPS-----SGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFS 11596

Query: 512   SKVEITPESILSA------LSKTQTQSAPALQGL--SSLLQSVTGN--------PVPASE 555
              +   T  S++++           T   P++ G+  S +  S T          P P   
Sbjct: 11597 HRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEP 11656

Query: 556   AASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSP 615
               + S++  P   T  T+  R +PSS    +     + P +ST    +TS+   S   + 
Sbjct: 11657 ETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDAT 11716

Query: 616   GLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNF 675
              + +T+ +  ++S   T     SP AP        +S+++     + +T P+L       
Sbjct: 11717 PVMATSPRTEASSAVLT---TISPGAPE-----MVTSQITSSGAATSTTVPTLTHS---- 11764

Query: 676   LKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQ 735
                     G+     +LS+   +  S++ P+       S +  ++   P  +  +  PTQ
Sbjct: 11765 -------PGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQ 11817

Query: 736   DEMMDKPTSSSVDTMSL-------LSKIISPGSSTPSSTRSPPPGRDES 777
                    T+SS+ T+ +       LS   SPG S  ++  S  PG + S
Sbjct: 11818 -------TTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETS 11859



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 167/732 (22%), Positives = 277/732 (37%), Gaps = 109/732 (14%)

Query: 316  PEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSD 375
            P  S + SP+  +PSP  S               T+    S++P PVT        + +D
Sbjct: 7970 PSFSLMSSPATTSPSPVSS---------------TLPESISSSPLPVTSLLTSGLAKTTD 8014

Query: 376  VEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNT 435
            +    S+ +       PA  S  STSV    T  ++  +  T      T T      V T
Sbjct: 8015 MLHKSSEPVT----NSPANLS--STSVEILATSEVTTDTEKTHPSSNRTVT-----DVGT 8063

Query: 436  SLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVS---PASRPSPGTPTSP-SNLTS 491
            S S   + +   LA+   +K++S +  +TS M++T VS   P    +    T P S+LT 
Sbjct: 8064 SSSGHESTSFV-LADSQTSKVTSPM-VITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTL 8121

Query: 492  GL-KTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP 550
            GL KT +   T+    ++ +LS V   P    + +S+T+  S+ +   +S   Q +T +P
Sbjct: 8122 GLRKTSSSEGTSLATEMSTVLSGV---PTGATAEVSRTEVTSS-SRTSISGFAQ-LTVSP 8176

Query: 551  VPASEAASQ-STSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKA 609
              ++E  ++  TS+    +    IK +  P  + P    + + S   +  E  ST   + 
Sbjct: 8177 ETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRF 8236

Query: 610  SIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESES------ 663
            S  +   L S   + P + L         P+    E T   SS +S P   S S      
Sbjct: 8237 SHSEMTTLVS---RSPGDMLW--------PSQSSVEETSSASSLLSLPATTSPSPVSSTL 8285

Query: 664  --TSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNID 721
                PS  + + + L  NPG       + I    G+S+ S    +  +R   +T  D +D
Sbjct: 8286 VEDFPSASLPVTSLL--NPGLVITTDRMGISREPGTSSTSNLSSTSHER--LTTLEDTVD 8341

Query: 722  GTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPR- 780
                 D +  T T    +    S      S+LS   +P +++P  T         +Y   
Sbjct: 8342 ---TEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGT---------TYTMG 8389

Query: 781  ELSNSVSTYRPF---------------GLGSESPYKQPSDGMERPSSLMDSSQEKFYPDT 825
            E S S+ST   F               GL   S  ++ S   E  S+++         + 
Sbjct: 8390 ETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATE-GSTVLSEVPSGATTEV 8448

Query: 826  SFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGV 885
            S  E    R    SGP    +      P  S    ++LS +    PI++  +  A     
Sbjct: 8449 SRTEVISSRGTSMSGPDQFTI-----SPDISTEAITRLSTS----PIMTESAESAITIET 8499

Query: 886  KSAFPPSVRAL-LDSSENC----DRLSSSPGLFGA--FSVRGNEPGSDRSPSPSKNDSFF 938
             S    S   L LD+S          ++SPG   +   ++    PG    PS    +   
Sbjct: 8500 GSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEAS 8559

Query: 939  TPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNT--LAAPTGHPPTSGVEKV 996
            +  S+ +S + ++T   S   +    SPHPV       P  T  +   +  P TS    +
Sbjct: 8560 SVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNL 8619

Query: 997  LASTISTTSTIE 1008
             +++    +T E
Sbjct: 8620 SSTSAEILATSE 8631



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 152/661 (22%), Positives = 237/661 (35%), Gaps = 105/661 (15%)

Query: 323  SPSMDAPSPT--------GSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELS 374
            SP MD  S T        GS +  +G   E + S  + S   A     +D+       LS
Sbjct: 4021 SPYMDTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLS 4080

Query: 375  D---VEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTA------ 425
            +   + + G  I+      + +   A S S PT  T   S  +S T  P+  T       
Sbjct: 4081 NFPAMTESGGMILAM----QTSPPGATSLSAPTLDT---SATASWTGTPLATTQRFTYSE 4133

Query: 426  -TPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPT 484
             T    K    +  PSP       ++  L  I +  S    ++ + G SP+S P P T  
Sbjct: 4134 KTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTP-PVTSV 4192

Query: 485  SPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQ 544
              S  TSGL      +  S  P  ++   +  T    LS    ++   A         + 
Sbjct: 4193 FLSE-TSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKA---------IH 4242

Query: 545  SVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSST 604
                  V   EA S   S  P +T  S      + S     I  S +   +S T+E+ + 
Sbjct: 4243 HSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETV 4302

Query: 605  SASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESEST 664
            S    S+ Q     ST+    S +   T   + S     T VT  Q++  S   + S   
Sbjct: 4303 S----SVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSP-- 4356

Query: 665  SPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTP 724
                    H F+     F+ ++ N P  S + + +   +  +  Q GPT  +     G  
Sbjct: 4357 --------HQFITSTNTFTDVSTN-PSTSLIMTESSGVTITT--QTGPTGAATQ---GPY 4402

Query: 725  VRDERSGTPTQDEMMDKPTSSSVDTM-SLLSKIISPGSSTPSSTRSPPPGRDESYPRELS 783
            + D    T T   + + P + + D M S  + +IS G    S T SPP   + SYP  L+
Sbjct: 4403 LLD----TSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWT-SPPSVAETSYPSSLT 4457

Query: 784  NSVSTYRP------FGLGSESPYKQPS---DGMERPSSLMDSSQEKFYPDTSFQEDEDYR 834
              + T  P       G  + SP    S    G+ + + ++++S E               
Sbjct: 4458 PFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSME--------------- 4502

Query: 835  DFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVR 894
                  P  ++  NL   P+  IL  + L+ TT+ + I  S +      G  S+      
Sbjct: 4503 ------PVTNSPQNL-NNPSNEIL--ATLAATTDIETIHPSINKAVTNMGTASSAHVLHS 4553

Query: 895  ALLDSSENCDRLS-----SSPG-LFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLS 948
             L  SSE     S     SS G    + S+    PGS+ +    +  S  T     NS  
Sbjct: 4554 TLPVSSEPSTATSPMVPASSMGDALASISI----PGSETTDIEGEPTSSLTAGRKENSTL 4609

Query: 949  Q 949
            Q
Sbjct: 4610 Q 4610



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 116/521 (22%), Positives = 198/521 (38%), Gaps = 70/521 (13%)

Query: 308   QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQS----PTMESEKSATPEP-V 362
             Q   T+P        S S   PS T S        G ES S    PT+ +E      P V
Sbjct: 10830 QTSPTVPWTTSIFFHSKSDTTPSMTTSH-------GAESSSAVPTPTVSTEVPGVVTPLV 10882

Query: 363   TDNRDVED-----MELSDVEDDGSKIIVEDRKEKPAEK---SAVSTSVPTKPTENI--SK 412
             T +R V       + LS  E + +  +     E+ +       VS  VP   T  +  S+
Sbjct: 10883 TSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSR 10942

Query: 413   ASSCTPVPV-TMTATPPLPKP-VNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNT 470
             A + T +P+ T +   P   P + TS       A+P +       ++S+++S  +V   T
Sbjct: 10943 AVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTT 11002

Query: 471   GVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQT 530
                P    SPG P +  ++ +     A +T  + +P      +V     S++++ S   +
Sbjct: 11003 --LPTLTLSPGEPETTPSMATSHGAEASSTVPTVSP------EVPGVVTSLVTSSSGVNS 11054

Query: 531   QSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKG---------RNLPSS 581
              S P L      L++    P  A+   ++++SA P  T    + G         R + S+
Sbjct: 11055 TSIPTLILSPGELETT---PSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTST 11111

Query: 582   AQPFIPKSFNYSPNSSTSEVSS--TSASKASIGQSPGLPSTTFKLPSNSLGFTATH---- 635
               P +  S +  P ++ S  +S    AS A +  SP +P     L ++S   T+T     
Sbjct: 11112 TIPILTLSSS-EPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTL 11170

Query: 636   NTSPAAPPTEVTICQSSEVSK-PKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSS 694
               S   P T  ++   SE      + + + SP+++  + + +  +   +    N+ + SS
Sbjct: 11171 TISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASS 11230

Query: 695   L-----------GSSAPSESHPSDFQRGPTSTSI-------DNIDGTPVRDERSGTPTQD 736
                         G+ A S         G   T+I       ++    P    R      D
Sbjct: 11231 QPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELD 11290

Query: 737   EMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES 777
              M    TS   ++ S +S  ISPG     ++     GRD S
Sbjct: 11291 TMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDIS 11331



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 157/729 (21%), Positives = 272/729 (37%), Gaps = 111/729 (15%)

Query: 323  SPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSK 382
            SPS++ PS   S             S T+    S++P PVT       +  +D+     +
Sbjct: 7087 SPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPE 7146

Query: 383  IIVEDR-KEKPAEKSAVSTSVPTKPTENI----SKASSCTPVPVTMTATPPLP-KPVNTS 436
            ++     K        ++T   T  TE +    + A+S   +P +   +P        TS
Sbjct: 7147 LVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETS 7206

Query: 437  LSPSP------------ALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPT 484
             + SP            A++ P+       +  SI SSL+  ++ TG S  +  +  T  
Sbjct: 7207 KATSPMFITSTQEDTTVAISTPHFLETSRIQKESI-SSLSPKLRETGSSVETSSAIETSA 7265

Query: 485  SPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSK-TQTQSAPALQGLSSL- 542
              S ++ G  T    T  + +   +I    E T    +S   K  +  ++P L   S + 
Sbjct: 7266 VLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMT 7325

Query: 543  LQSVTGNPVPASEAA-SQSTSASPANTTVSTIKGRNLP-SSAQPFIPKSFNYSPNSSTSE 600
            +++ T  P   SE+  +  TS +P+     +   + LP S     + +     P  S+  
Sbjct: 7326 IKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLP 7385

Query: 601  VSSTSASKASIGQ----SPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSK 656
            V  TS   + +      SP   S+T    S+S   + T   +P    T       +EV  
Sbjct: 7386 VEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKT-------TEVLD 7438

Query: 657  PKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTS 716
               E E++SP             P  S  ++ I + +S  ++   + HP       ++T+
Sbjct: 7439 ASAEPETSSP-------------PSLSSTSVEI-LATSEVTTDTEKIHPF------SNTA 7478

Query: 717  IDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLS----KIISPGSSTPSSTRSPPP 772
            +  +  +    E   +   D    K T S++ T+S++       ++P  S     +S P 
Sbjct: 7479 VTKVGTSSSGHESPSSVLPDSETTKAT-SAMGTISIMGDTSVSTLTPALSNTRKIQSEPA 7537

Query: 773  GRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDED 832
                +  RE S S  T     L +E+            ++++         + S  E   
Sbjct: 7538 SSLTTRLRETSTSEET----SLATEA------------NTVLSKVSTGATTEVSRTEAIS 7581

Query: 833  YRDFEYSGPPPSAMM------NLEKKPAKSIL-KSSKLSDTTEYQPILSSYSHRAQEFGV 885
            +     SGP  S M        + +  A S+L +S+K++ TT+  P   S S       +
Sbjct: 7582 FSRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMTITTQTGP---SESTLESTLNL 7638

Query: 886  KSAFPPS---VRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPS--KNDSFFTP 940
             +A  PS     +++        +++S G       RG  PG    PSP   K  S   P
Sbjct: 7639 NTATTPSWVETHSIVIQGFPHPEMTTSMG-------RG--PGGVSWPSPPFVKETS---P 7686

Query: 941  DSNHNSLSQSTTGH--LSLPQKQYPDSPHPVPHRSLFSPQNT--LAAPTGHPPTSGVEKV 996
             S+  SL   T+ H   +      P SP PV       P  T  +   +  P TS     
Sbjct: 7687 PSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSS---- 7742

Query: 997  LASTISTTS 1005
             +S++STTS
Sbjct: 7743 -SSSLSTTS 7750



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 92/386 (23%), Positives = 151/386 (39%), Gaps = 59/386 (15%)

Query: 433  VNTSLSPSPA-LALPNLANVDLAKISSILSSLTSVMKNTGVSPA-SRPSPGTPTSPSNLT 490
            + T +S  P  ++ P+  +V+     S L SL++V   T  SP  S PS  + +SP  +T
Sbjct: 8828 MTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAV---TSPSPLYSTPSESSHSSPLRVT 8884

Query: 491  SGLKTPAPATTT-----SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQS 545
            S L TP    TT     S  P+      + IT +  L+    T    A  L   +++ Q 
Sbjct: 8885 S-LFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQM 8943

Query: 546  VT-------GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSST 598
             T        +  P     S+ TS    ++T+  I    +P+S++    +  + S  + T
Sbjct: 8944 GTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPT 9003

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPK 658
               +STS    S  +   +P       +     T   ++S    P + T+  S ++S   
Sbjct: 9004 PRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTM--SQDISTEV 9061

Query: 659  LESESTSP----SLEMKI--------------------HNFLKGNPGFSGLNLNIPILSS 694
            +   STSP    S EM I                      F+ G    +    +   +++
Sbjct: 9062 ITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTA 9121

Query: 695  LGSSAPSE----SHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTM 750
            L S  P +    SHPS  +    S S+     +PV    S +P    + D   SSS+   
Sbjct: 9122 LMSRTPGDVPWLSHPSVEEASSASFSL----SSPVM--TSSSPVSSTLPDSIHSSSLPVT 9175

Query: 751  SLLSKIISP-----GSSTPSSTRSPP 771
            SLL+  +       G+S+   T SPP
Sbjct: 9176 SLLTSGLVKTTELLGTSSEPETSSPP 9201



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 157/759 (20%), Positives = 275/759 (36%), Gaps = 98/759 (12%)

Query: 395  KSAVSTSVP--TKPT---------ENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPA- 442
            K+A  +S P  TKP+         E  S  SS      ++  TP   +   +S  P  A 
Sbjct: 657  KTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAG 716

Query: 443  -----LALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPA 497
                  ++P L++  + +     +S  S  K T       P   T T PS+      T +
Sbjct: 717  HTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLS 776

Query: 498  PATTTSH------NPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP- 550
             A T+        +PL +     E T  S+L+  +  +T  +P +    +L    + +P 
Sbjct: 777  NAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPS 836

Query: 551  ---VPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS 607
               +P+      + S+S  +T + T  G     ++ P + +     P +S S V +T AS
Sbjct: 837  TLSLPSVSGVKTTFSSSTPSTHLFT-SGEETEETSNPSVSQ-----PETSVSRVRTTLAS 890

Query: 608  KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS 667
             +    +P  P T    P+ S  F+++H  S     +  ++  S+  + PK+   + + +
Sbjct: 891  TSV--PTPVFP-TMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTAT 947

Query: 668  LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD 727
            +     +    +          P  ++   ++P             STS  ++  T V  
Sbjct: 948  MSQTNRDTFNDSAA--------PQSTTWPETSPRFKTGLPSATTTVSTSATSLSAT-VMV 998

Query: 728  ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSP------PPGR-DESY-P 779
             +  +P    M          T+        PGS   +ST  P        GR D S+ P
Sbjct: 999  SKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLP 1058

Query: 780  RELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYS 839
               + S  T   F +  ES     S     PS  MD++     P  + Q  + + D  Y 
Sbjct: 1059 IGTTASSETSMDFTMAKESVSMSVS-----PSQSMDAAGSS-TPGRTSQFVDTFSDDVYH 1112

Query: 840  GPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFP--PSVRALL 897
                S  + + +    S L       T  + P     S R+   G+ S+ P  P+ +  +
Sbjct: 1113 --LTSREITIPRDGTSSALTPQM---TATHPPSPDPGSARSTWLGILSSSPSSPTPKVTM 1167

Query: 898  DSSENCDRLSSSPGLFGAFSVRGNEPG--SDRSPSPSKNDSFFTPDSNHNSLSQSTTGHL 955
             S+ +  R+++S  +    + R N P   S  S +PS       P S   ++ +ST   L
Sbjct: 1168 SSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSN-----IPTS--GAIGKSTLVPL 1220

Query: 956  SLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKV-----LASTISTTSTIEFK 1010
              P           P  SL + +  L   + +P ++    +      +S   +T  +   
Sbjct: 1221 DTPS----------PATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMA 1270

Query: 1011 NMLKNASRK----PSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIET- 1065
            +++K  S      PS + H   + ++   S G S   +T P  T T        Y   T 
Sbjct: 1271 SVVKPGSYTPLTFPSIETHIHVSTARMAYSSG-SSPEMTAPGETNTGSTWDPTTYITTTD 1329

Query: 1066 --RVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEP 1102
                SS+ +  P S              SA+    SG P
Sbjct: 1330 PKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSP 1368



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 183/853 (21%), Positives = 291/853 (34%), Gaps = 136/853 (15%)

Query: 476  SRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPA 535
            SR +  TP   S LT    T +P T+T    +           +++ S  S    ++  +
Sbjct: 21   SRSTKATPEMDSGLTGA--TLSPKTSTGAIVVTEHTLPFTSPDKTLASPTSSVVGRTTQS 78

Query: 536  LQGLSSLLQSVTGNPVPASEAASQSTSASPANTT-------VSTIKGRNLPSSAQPFIPK 588
            L  +SS L   T   +  SE  +  + +   N T        S + G + P +       
Sbjct: 79   LGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEG 138

Query: 589  SFNYSPNSSTSEVSSTSASKASIGQSPGLPSTT---------------FKLPSNSLGF-- 631
            +F    ++ T  V +TS         P   STT                K+ S    F  
Sbjct: 139  NFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFAD 198

Query: 632  -TATHNTSPAA-PPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFL----KGNPGFSGL 685
             TA+   +P +  P E T+  S    +       T+PS      +FL    KG P   G 
Sbjct: 199  STASKENAPVSMTPAETTVTDSHTPGR-------TNPSFGTLYSSFLDLSPKGTPNSRGE 251

Query: 686  NLNIPILSSLGS--SAP---SESHPSDFQRGPTSTS---IDN-IDGTPVRDERSGTPTQD 736
                 ILS+ G   S+P   S  H       P S+S   +DN I  T +   +S T    
Sbjct: 252  TSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLS 311

Query: 737  EMMDKPTSSSVDTMSL-LSKIISPGSSTPSSTRSPPP--GRDESYPRELSNSVSTYRPFG 793
              + +  +S++   ++  S  +S   ++    RS     G      ++ + ++ T+  F 
Sbjct: 312  PGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFA 371

Query: 794  LGSESPYKQ-----PSDGMERPSSLMDSSQEKFY---PDTSFQEDEDYRDFEYSGPPPSA 845
               + P         S+ +  P +L  +S        P T+   +E       SG     
Sbjct: 372  ETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEG 431

Query: 846  MMNLEKKPAKSILKSSKLSDTTEYQPILSSY---SHRAQEFGVKSAFPPSVRALLDSSEN 902
             +N    P ++     +   T    P L      S       V S+ P   R L  +   
Sbjct: 432  TLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHP--TRELRTTGST 489

Query: 903  CDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQY 962
              R SSS    G+  +         + S SK  S+          S+ST    S PQ   
Sbjct: 490  SGRQSSSTAAHGSSDIL-----RATTSSTSKASSW---------TSESTAQQFSEPQHTQ 535

Query: 963  PDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLA--STISTTSTIEFKNMLKNASRKP 1020
                 P           ++AAP     T+ V  V++  +T+ T+ST   K +    +   
Sbjct: 536  WVETSPSMKTERPPASTSVAAPI----TTSVPSVVSGFTTLKTSST---KGIWLEET--- 585

Query: 1021 SDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSS-SCLDLPDSTE 1079
            S D   G++ +  T       + ++    ++T   Q   H       SS +  DL  +T 
Sbjct: 586  SADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATN 645

Query: 1080 EKGAPIETLGYHSASNRRMSG--EPIQTVESIRVPGKGNRGHG--REASRVGWFDLSTSG 1135
                 +      +A+     G  +P  T+ S  +P   +      RE + +G   L+T  
Sbjct: 646  GVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRH 705

Query: 1136 SSFDNGPSSASELASLGGGGSGGLTGFKTA-PYKERAPQFQESVGSFRSNSFNSTFEHHL 1194
                  P SA            G T   T+ P    A   ++ V      S  STF HH 
Sbjct: 706  PFSSPEPDSA------------GHTKISTSIPLLSSASVLEDKV------SATSTFSHHK 747

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
              S +  GTP       PSSA                   L S+ LSN  T    + +A 
Sbjct: 748  ATSSITTGTPEISTKTKPSSAV------------------LSSMTLSNAATSPERVRNAT 789

Query: 1255 P----PPPPGEHS 1263
                 P P GE +
Sbjct: 790  SPLTHPSPSGEET 802



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 149/713 (20%), Positives = 262/713 (36%), Gaps = 117/713 (16%)

Query: 393  AEKSAVSTSVPTKPTENISKASSCTPVPV-TMTATPPLPKPVNTSLSPSPALALPNLANV 451
            A    +ST++ T  T +IS  +    V + TM +TP   +   ++  PS      + A  
Sbjct: 3533 APTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTSTEHPS---TWSSTAAS 3589

Query: 452  DLAKISSILSSLT--------SVMKNTGVSPASRPSPGTPTSPSNLT---SGLKTP---A 497
            D   ++ + S+L         S M  T    +S       T    +T   + L TP   A
Sbjct: 3590 DSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDA 3649

Query: 498  PATTTSHNPLANILSKVEITPESILSALSKTQTQS--APALQGLSSLLQSVTGNPVPASE 555
             A  T  +     LS  + T  + +S  S+ Q  S   P +   S    S     VP S 
Sbjct: 3650 SAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSM 3709

Query: 556  AASQ--STSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQ 613
             ++   ST   P NT +ST    +L          + ++    S S  ++T+++      
Sbjct: 3710 VSTDHASTKTDP-NTPLSTFLFDSL---------STLDWDTGRSLSSATATTSAPQGATT 3759

Query: 614  SPGLPSTTFKLPSNS-LGFTATHNTSPAAPP-----TEVTICQSSEVSKPKLESESTSPS 667
               L   T   P+ S L F+  H TS   P      + VT  +    SK   ++E TS  
Sbjct: 3760 PQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSK---KAEQTSTQ 3816

Query: 668  LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQR-GPTSTSID-------- 718
            L           P  +   L++           +++  + FQR G T+ + +        
Sbjct: 3817 LPTTTSAHPGQVPRSAATTLDV-------IPHTAKTPDATFQRQGQTALTTEARATSDSW 3869

Query: 719  -----NIDGTPVRDERSGTPTQDEMMDKPTSSSV-DTMSLLSKIISPGSSTPSSTRSPP- 771
                 +    P   E   + ++D + +  +SSSV  T++ L   +  G+++  S +S P 
Sbjct: 3870 NEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSPY 3929

Query: 772  ----PGRDESYPRELSNSVSTYRPFGLGSES--------PYKQPSDGMERPSSLMDSSQE 819
                P    +    +  S +T    G  + S        P    S  +  P     + ++
Sbjct: 3930 ERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQ 3989

Query: 820  KFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHR 879
                 ++    E  R    +   P++ + +E +     + +S  + T+    I+SS    
Sbjct: 3990 AIVSMSTTTWPESTR----ARTEPNSFLTIELRDVSPYMDTSSTTQTS----IISSPGST 4041

Query: 880  AQEFG----------VKSAF-PPSVRALLDSSENCDRLSSSPGLFGA----FSVRGNEPG 924
            A   G          + S+F   S+R+    SE   RLS+ P +  +     +++ + PG
Sbjct: 4042 AITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPG 4101

Query: 925  SDRSPSPSKNDSFF-----TP--DSNHNSLSQSTTGHLSLPQKQYPDSPHPV-------- 969
            +    +P+ + S       TP   +   + S+ TT     P+     SP  V        
Sbjct: 4102 ATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSS 4161

Query: 970  --PHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKP 1020
              P  +  SP N L    GH P+S    V +  +S TS +     +   S +P
Sbjct: 4162 LVPIHATTSPSNILLTSQGHSPSS-TPPVTSVFLSETSGLGKTTDMSRISLEP 4213



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 85/396 (21%), Positives = 142/396 (35%), Gaps = 78/396 (19%)

Query: 308   QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQS-----PTMESEKSATPEPV 362
             Q+ ST+P       P    D P  T S +    +G E S +     P++ + +S T   +
Sbjct: 10514 QMASTIPTEMMITTPYVFPDVPETTSSLAT--SLGAETSTALPRTTPSVFNRESETTASL 10571

Query: 363   TDNRDVE--------DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPT--KPTENISK 412
                   E        D+  S+ +   S +I       PAE      ++PT  K T N   
Sbjct: 10572 VSRSGAERSPVIQTLDVSSSEPDTTASWVI------HPAE------TIPTVSKTTPNFFH 10619

Query: 413   ASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGV 472
             +   T      +    +   + T++SPS   AL  L  +     S+   +LT     T  
Sbjct: 10620 SELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFPTLTKSPHETET 10679

Query: 473   SPA--SRPSPGTPTSP----------SNLTSGLKTPAPATTTSHNPLANILSKVEITPES 520
                  + P+  + T P          S+ T  + T   A T+S  P+  +    E    S
Sbjct: 10680 RTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTS 10739

Query: 521   ILSALSKTQTQSAPALQ---GLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRN 577
              +++    +  + P L    G    + S+  +P   + +A  +++ SPA + + T     
Sbjct: 10740 QVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVT----- 10794

Query: 578   LPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNT 637
                              +  TS  + TS +  ++  SPG P+TT  L       T    T
Sbjct: 10795 -----------------SMVTSLAAKTSTTNRALTNSPGEPATTVSL------VTHPAQT 10831

Query: 638   SPAAPPTEVTICQSSEVSKPKL------ESESTSPS 667
             SP  P T      S   + P +      ES S  P+
Sbjct: 10832 SPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPT 10867



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 192/917 (20%), Positives = 329/917 (35%), Gaps = 132/917 (14%)

Query: 317  EESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDV 376
            EE P  + S       G+ +  Q +    S++PT     S+  EP    +       S  
Sbjct: 3089 EEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRK-------SSP 3141

Query: 377  EDDGSKIIVEDRKEKPAEKSAVSTSVPT-----KPTENISKASSCTPVPVTMTATPPLPK 431
            E   S I V      PA+ S V T+  T     K +   ++ +S  P P   T +     
Sbjct: 3142 ETWASSISV------PAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGS----S 3191

Query: 432  PVNTSL-SPSPALALPNLANVDLAKISSILSSL---------TSVMKNTGVSPASRPSPG 481
            P  TS  SP  +  L  +++ + +    I S++         T+V   T V P +  S  
Sbjct: 3192 PAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTA 3251

Query: 482  TPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEIT-----PESILSALSKTQTQSAPAL 536
                 S  TS    P   T+ + +P  N+L+   ++     PE+  +  S T   +  +L
Sbjct: 3252 L---GSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSL 3308

Query: 537  QGLSSL------LQSVTGNPVPAS-EAASQSTSASPA---NTTVSTIKGRNLPSSAQPFI 586
              +SS+       +S+TG    +S E  S++T    +    +T  T    ++  S    I
Sbjct: 3309 ATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNI 3368

Query: 587  PKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTF--------KLPSNSL--GFTATHN 636
             +    SPNS +S    +     +   +  +PST          +  S S+   +++T +
Sbjct: 3369 LEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSS 3428

Query: 637  TSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLG 696
             S     +++T+  S +V+        TS +    + +   G+ G + L       +S  
Sbjct: 3429 WSDQTSGSDITLGASPDVTNTLY---ITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSA 3485

Query: 697  SSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKI 756
            SS  S S   +  R   S    +I  T     ++ +P +  ++D  T+            
Sbjct: 3486 SSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAP----------- 3534

Query: 757  ISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDS 816
             +PG ST  +T               +NS+ST  P           P  GM    S MDS
Sbjct: 3535 -TPGISTTITTMG-------------TNSISTTTP----------NPEVGM----STMDS 3566

Query: 817  SQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKS------ILKSSKLSDTTEYQ 870
            +       TS +    +     S       M    K A+S      +  +S L+ +TE  
Sbjct: 3567 TPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELD 3626

Query: 871  PILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRS-- 928
              +S+   R    G     P S  + + +  +    + SP    A +         R   
Sbjct: 3627 S-MSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSI 3685

Query: 929  PSPSKNDSFFTPDSNHNS---LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPT 985
              P    + +TP S       +S  +T H S   K  P++P       LF   +TL   T
Sbjct: 3686 SVPDILSTSWTPSSTEAEDVPVSMVSTDHAS--TKTDPNTPLST---FLFDSLSTLDWDT 3740

Query: 986  GHPPTSGVEKVLASTISTT-STIEFKNMLKNA-SRKPSDDKHFGQAPSKGTPSDGVSLSN 1043
            G   +S      A   +TT   +  + M+  A S+ P      G   S  TP+     S 
Sbjct: 3741 GRSLSSATATTSAPQGATTPQELTLETMISPATSQLPFS---IGHITSAVTPAAMARSSG 3797

Query: 1044 LTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPI 1103
            +T      T ++ ++   ++ T  S+    +P S       I        +  +  G+  
Sbjct: 3798 VTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTA 3857

Query: 1104 QTVESIRVPGKGNRGHGREASRVGWFDL--STSGSSFDNGPSSASELASLG------GGG 1155
             T E+       N       S     ++  S S  +     SS+S L +L         G
Sbjct: 3858 LTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESG 3917

Query: 1156 SGGLTGFKTAPYKERAP 1172
            +     +K++PY+  AP
Sbjct: 3918 TTSSPSWKSSPYERIAP 3934



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 180/876 (20%), Positives = 308/876 (35%), Gaps = 165/876 (18%)

Query: 9    SSKASSSSASSAGALESSLDRKF---QSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKW 65
            SS  +SS   +AG +++SL+      QS++NT++ I   S+   + +  H +I       
Sbjct: 4776 SSVLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSI------- 4828

Query: 66   LRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFK 125
                            N V+ N     +     S     PE +  V  P+V+ S      
Sbjct: 4829 ----------------NTVVTNVGTTGSAFESHSTVSAYPEPSK-VTSPNVTTSTMEDTT 4871

Query: 126  IWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIV 185
            I   R++ P+       E  +T+  T K  + +++++       ++TST P   L     
Sbjct: 4872 I--SRSI-PKSSKTTRTETETTSSLTPKLRETSISQEITSS---TETSTVPYKELTGATT 4925

Query: 186  AEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEE 245
               R+            S           ST+ +D+ STET      +        E  E
Sbjct: 4926 EVSRTDVT---------SSSSTSFPGPDQSTVSLDI-STET----NTRLSTSPIMTESAE 4971

Query: 246  ASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKK 305
             +   +   +G   Q       +     AGI           + + +      V  L  +
Sbjct: 4972 ITITTQTGPHGATSQDTFTMDPSNTTPQAGIH--------SAMTHGFSQLD--VTTLMSR 5021

Query: 306  LDQLKS-TLP---DPEESP---VPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSAT 358
            + Q  S T P   D   SP   + SP+M  PS   S  P      E+  S  M S  ++ 
Sbjct: 5022 IPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLP------EDKLSSPMTSLLTSG 5075

Query: 359  PEPVTD----NRDVEDMELSDVEDDGSKIIVEDRKEKPAEK--SAVSTSVPTKPTENISK 412
               +TD      +     L +      KI+   +  K  ++   +++T        N   
Sbjct: 5076 LVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGH 5135

Query: 413  ASSCTPVPVTMTATPPLPKPVNTSLS-PSPALALPNLANVDLAKISSILSS-LTSVMKNT 470
             S    +  + T        + T++  P+P+ ++P   + +   I    +  LT  ++ T
Sbjct: 5136 ESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRET 5195

Query: 471  GVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVE--------ITPESIL 522
              S  S      PT  S L S  K P    T   +   N  SK+         + P++  
Sbjct: 5196 STSQES----SFPTDTSFLLS--KVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFT 5249

Query: 523  SALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSA 582
              + +  T S        S   ++T    P  E+AS ST     +TT+S     +  +  
Sbjct: 5250 GEIPRVFTSSIKT----KSAEMTITTQASPP-ESASHSTLPLDTSTTLSQGGTHSTVTQG 5304

Query: 583  QPFI---------PKSFNYS---PNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLG 630
             P+          P + ++    P   TS VSS  +S A    SP   ++   +PS+ L 
Sbjct: 5305 FPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLP 5364

Query: 631  FTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIP 690
             TA         PT V +  +  +     ES ++SP                       P
Sbjct: 5365 VTAL--------PTSVLVTTTDVLGTTSPESVTSSP-----------------------P 5393

Query: 691  ILSSLGSSAPS----ESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMM-DKPTSS 745
             LSS+    P+     +H        T+T++ N+ GT      SG  +Q  ++ D  TS 
Sbjct: 5394 NLSSITHERPATYKDTAHTEAAMHHSTNTAVTNV-GT----SGSGHKSQSSVLADSETSK 5448

Query: 746  SVDTMSLLSKI--ISPGSSTPSSTRS-----------PPPGRDESYPRELSNSVSTYRPF 792
            +   MS  S +   S  +STP+ +++            P  R+ S   + S++  T   F
Sbjct: 5449 ATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAF 5508

Query: 793  GLGSESPYKQPS--DGMERPSSLMDSSQEKFYPDTS 826
                     Q S  +     +S+ D  +    PD S
Sbjct: 5509 SYVPTGAITQASRTEISSSRTSISDLDRPTIAPDIS 5544



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 110/519 (21%), Positives = 189/519 (36%), Gaps = 28/519 (5%)

Query: 315   DPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEP-VTDNRDVEDMEL 373
             D   S V SP +D  S   + +    + G  +   T  +  ++T  P +T +    +   
Sbjct: 11601 DTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTA 11660

Query: 374   SDVEDDGSKI-IVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKP 432
             S     G++       +  P+ +     S  T P +  +  S  T    + + + P   P
Sbjct: 11661 SSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTS---SFSHSSPDATP 11717

Query: 433   VNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVS-PASRPSPGTPTSPSNLTS 491
             V  + SP    +   L  +       + S +TS    T  + P    SPG P      T+
Sbjct: 11718 VMAT-SPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPE-----TT 11771

Query: 492   GLKTPAPATTTSHN-PLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQS-VTGN 549
              L +  P T TS   P + +  +V  T  S L+     +T +A   Q  SSL    VTG 
Sbjct: 11772 ALLSTHPRTETSKTFPASTVFPQVSETTAS-LTIRPGAETSTALPTQTTSSLFTLLVTGT 11830

Query: 550   P-VPASEAASQSTSA--SPANTTVSTIKGRNLPSSAQPF-IPKSFNYSPNSSTSEVSSTS 605
               V  S  AS   SA  +P +T   T     +P+S     + ++      SS++E S+++
Sbjct: 11831 SRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTST 11890

Query: 606   ASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTS 665
              +        GL S +          +    TSP+     VT     E S+    +  T 
Sbjct: 11891 LTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPS-----VTSVGPPEFSRTVTGTTMTL 11945

Query: 666   PSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPV 725
                EM          G S   +    +    + A + S P+  +   T  ++     TP+
Sbjct: 11946 IPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGSLFTPL 12005

Query: 726   RDERSGTPTQDEMMDKPTSSSVDTMSLLS----KIISPGSSTPSSTRSPPPGRDESYPRE 781
                   T   + +  + + +    +S  S    +  +P +STP ++   P     S P  
Sbjct: 12006 TTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTSTFSPGISTSSIPSS 12065

Query: 782   LSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEK 820
              + +V    PF L       Q  + M  P S   ++ E+
Sbjct: 12066 TAATVPFMVPFTLNFTITNLQYEEDMRHPGSRKFNATER 12104



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 201/981 (20%), Positives = 329/981 (33%), Gaps = 157/981 (16%)

Query: 446  PNLANVDLAKISSILSSLTSVMKN--------TGVSPASRPSPGTPTS----------PS 487
            P  A       S+ LSS  SV+ N        +G S  S  SPG P +          P 
Sbjct: 270  PGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNSAIPF 329

Query: 488  NLT-SGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSV 546
            ++T S  +T A    ++ + L       + T E+IL+  +  +T   P+     +L    
Sbjct: 330  SMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEW 389

Query: 547  TGNP-VPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTS 605
             G+P      + S  T+ SP+ T VS     +  +S +              TS     S
Sbjct: 390  LGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEES 449

Query: 606  ASKASIGQSPGLPSTTFKLPSNS-------------LGFTATHNTSPAAPPTEVTICQSS 652
               A++  + G  +   K+ S S              G T+   +S  A      I +++
Sbjct: 450  EMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRAT 509

Query: 653  EVSKPKLE---SESTSPSLEMKIH-NFLKGNPGF------SGLNLNIPILSSLGS----- 697
              S  K     SEST+       H  +++ +P        +  ++  PI +S+ S     
Sbjct: 510  TSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGF 569

Query: 698  --------------SAPSESHPSDFQRGPTS------TSIDNIDGTPVRDERSGTPTQDE 737
                             +++   +   GPT+      T I    G+  R  +  T     
Sbjct: 570  TTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTT----H 625

Query: 738  MMDKPTSSSVDTMSL------LSKIISPGSSTPSSTRSPPPGRDESY-------PRELSN 784
            ++ + T+SS  +  L      +   +SP  S  ++  SPP G   SY       P   S 
Sbjct: 626  LLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSL 685

Query: 785  SVSTYRP------FGLGSESPYKQP---SDGMERPSS---LMDSS---QEKFYPDTSFQE 829
              S +R         L +  P+  P   S G  + S+   L+ S+   ++K    ++F  
Sbjct: 686  QSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSH 745

Query: 830  DEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSD-TTEYQPILSSYSHRAQEFGVKSA 888
             +         P     ++ + KP+ ++L S  LS+  T  + + ++ S           
Sbjct: 746  HKATSSITTGTPE----ISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEE 801

Query: 889  FPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRS-PSPSKNDSFFTPD--SNHN 945
               SV  L  S+E  D  +  P   G  +   +E  S  S PS S   + F+    S H 
Sbjct: 802  TAGSVLTLSTSAETTDSPNIHP--TGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHL 859

Query: 946  SLSQSTTGHLSLPQKQYPDS--------------PHPV-------PHRSLFSPQNTLAAP 984
              S   T   S P    P++              P PV       P RS     + L + 
Sbjct: 860  FTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSE 919

Query: 985  TGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNL 1044
                 ++ V     S +   S +     +   +R   +D     AP   T  +       
Sbjct: 920  LRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFND---SAAPQSTTWPETSPRFKT 976

Query: 1045 TQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQ 1104
              PS T T          +   V  S    P ++  +   I        +    +G    
Sbjct: 977  GLPSATTTVSTSATS---LSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSM 1033

Query: 1105 TVESIRVP-GKGNRGHGR-EASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGF 1162
             V S  +P GKG    GR + S +     ++S +S D   +  S   S+    S    G 
Sbjct: 1034 AVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGS 1093

Query: 1163 KTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKD 1222
             T     R  QF   V +F  + ++ T      P     GT     P   ++ PP P   
Sbjct: 1094 ST---PGRTSQF---VDTFSDDVYHLTSREITIP---RDGTSSALTPQMTATHPPSPDPG 1144

Query: 1223 HG-----GIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPG 1277
                   GI S    +  P V +S+ F+ +                 +P         P 
Sbjct: 1145 SARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPS 1204

Query: 1278 EHSSSGGSG----VPFSTPPP 1294
               +SG  G    VP  TP P
Sbjct: 1205 NIPTSGAIGKSTLVPLDTPSP 1225



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 145/680 (21%), Positives = 242/680 (35%), Gaps = 105/680 (15%)

Query: 312  TLPDPEESP----VPSPSMDAPSPTGSESP--------------------FQGMGGEESQ 347
            T P  EE+     + SPSM +PSP  S SP                       + G  S 
Sbjct: 5621 TTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSP 5680

Query: 348  SPTMESE---KSATPEPVTDNRDVEDMEL--------SDVEDDGSKII-VEDRKEKPAEK 395
             P   S     S T E +T  +D    E         + V + G+ I   E +   PA+ 
Sbjct: 5681 EPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADS 5740

Query: 396  SAVSTSVPTKPTENISKASSCTPVPV----------TMTATPPL-----PKPVNTSLSPS 440
                 + P   T  +   S  T  P           T +  P L      + +NT    S
Sbjct: 5741 HTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETS 5800

Query: 441  PALA-LPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPA 499
              L+ +P     ++++   I SS T++        +   S  T T  S       +   A
Sbjct: 5801 TVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMA 5860

Query: 500  TTTSHNPLANILSKVEITPESILSA----LSKTQTQSAPALQGLSSLLQSVTG----NPV 551
             T    P+  I S+  +T ++  +A         TQ  P  +  +++ +S  G    +P 
Sbjct: 5861 ITNQTGPIGTI-SQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPP 5919

Query: 552  PASEAASQSTSAS-PANTTVSTIKGRNLPSSAQPFIP-KSFNYSPNSSTSEVSSTSASKA 609
               E +S S+    PA T+ S++      SS    +P  S   S    T ++  T +   
Sbjct: 5920 SVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSE-- 5977

Query: 610  SIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSL- 668
                       T  LPS S  F+    TS A+  TE TI  S   ++  + + ++   L 
Sbjct: 5978 ---------LVTSSLPSAS-SFSGEILTSEASTNTE-TIHFSENTAETNMGTTNSMHKLH 6026

Query: 669  -EMKIHNFLKGN--PGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNI--DGT 723
              + IH+   G+  P  +G  +   I+S   +S P      +  R  TS     +  D T
Sbjct: 6027 SSVSIHSQPSGHTPPKVTGSMMEDAIVS---TSTPGSPETKNVDRDSTSPLTPELKEDST 6083

Query: 724  PV---RDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSP--PPGRDESY 778
             +       S T      +D  T  S   ++       P S+   ST+SP   P    S+
Sbjct: 6084 ALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASA--QSTKSPDISPEASSSH 6141

Query: 779  PRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEY 838
                  ++ST++       +    PS         +D+S       T     +D+ D E 
Sbjct: 6142 SNSPPLTISTHKTI-----ATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSET 6196

Query: 839  SGPPPSAMMNLEK------KPAKSILKSSKLSDTTEYQPILSSYSHRAQE--FGVKSAFP 890
            +    + + ++ K      + A S+   + L  TT   P+ S+    +      V S   
Sbjct: 6197 TSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPT 6256

Query: 891  PSVRALLDSSENCDRLSSSP 910
            P++  + D   N + ++ SP
Sbjct: 6257 PTLAKITDMDTNLEPVTRSP 6276



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 81/397 (20%), Positives = 142/397 (35%), Gaps = 52/397 (13%)

Query: 430  PKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNL 489
            P  V  + SPS  + LP + +      SS+ S+++           S P+   P + S L
Sbjct: 5918 PPSVEETSSPSSPVPLPAITSH-----SSLYSAVSG----------SSPTSALPVT-SLL 5961

Query: 490  TSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGN 549
            TSG +       T    + + L         IL++ + T T++    +  +      T +
Sbjct: 5962 TSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNS 6021

Query: 550  PVPASEAAS---QSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNY-----SPNSSTSEV 601
                  + S   Q +  +P   T S ++   + S++ P  P++ N      SP +   + 
Sbjct: 6022 MHKLHSSVSIHSQPSGHTPPKVTGSMMEDA-IVSTSTPGSPETKNVDRDSTSPLTPELKE 6080

Query: 602  SSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLES 661
             ST+    S  +S  + S+     +  +         P   P      +S ++S     S
Sbjct: 6081 DSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSS 6140

Query: 662  ESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPS----DFQRGPTSTSI 717
             S SP L +  H  +    G SG+     +     + A S   PS    DF    T++ +
Sbjct: 6141 HSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVM 6200

Query: 718  DN-------------------IDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSL----LS 754
            +N                       P+    S +P    + +  TSS V   S+    L+
Sbjct: 6201 NNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLA 6260

Query: 755  KIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRP 791
            KI    ++    TRSP   R+     E +    T  P
Sbjct: 6261 KITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHP 6297



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 91/404 (22%), Positives = 157/404 (38%), Gaps = 62/404 (15%)

Query: 319   SPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVED 378
             SP  S ++    P+ S S    +     ++    +E   +  P      VE +  S+V  
Sbjct: 10032 SPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTT 10091

Query: 379   DGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKP---VNT 435
             D  KI        P+   AV+    T     +  + S    P    AT P+  P     T
Sbjct: 10092 DTEKI-------HPSSSMAVTNVGTTSSGHELYSSVSIHSEP--SKATYPVGTPSSMAET 10142

Query: 436   SLSPS-PA-LALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPS-PGTP----TSPSN 488
             S+S S PA            + ++S        +  + V+P + PS PG+     +S ++
Sbjct: 10143 SISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTD 10202

Query: 489   LTSGLKTPAPA-------------TTTSHNPLANILSKVEIT--PES-----ILSALSKT 528
              TS  KT +P                T  N   +I     IT  PES     +  +    
Sbjct: 10203 FTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTHHL 10262

Query: 529   QTQSAPALQ---------GLSSLLQSVTGNPVPASEAASQS----TSASPANTTVSTIKG 575
              T   P+ +          LS  + S     VP + + S S    T + P + T+STI  
Sbjct: 10263 STDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTI-A 10321

Query: 576   RNLPSSAQ-PFIPKSFNYSPNS---STSEVSSTSASKASIGQSPGLPSTTFK---LPSNS 628
              +LPSS   PF   +F  + +S   +  E++S+SA+   +  S G  S+T +   +  ++
Sbjct: 10322 ESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVST 10381

Query: 629   LGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKI 672
             L  ++    + ++P  +  + +S E+    + S    PSL  ++
Sbjct: 10382 LDTSSQPGRTSSSPILDTRMTESVELG--TVTSAYQVPSLSTRL 10423



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 194/1010 (19%), Positives = 337/1010 (33%), Gaps = 138/1010 (13%)

Query: 239  FSKEFEEASSKLEEFVNGLDKQVKNGP---SLTEALENAGIFYEAQYKEVKVVANAYKTF 295
            F  E    SS+    V  L   V   P   S +  +  + +   +  K    V  + +T 
Sbjct: 4738 FQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETV 4797

Query: 296  ANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAP----SPTGS--ESPFQGMGGEESQSP 349
             +   ++   LD +  T     +     PS++        TGS  ES        E    
Sbjct: 4798 TSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAYPEPSKV 4857

Query: 350  TMESEKSATPEPVTDNRDV-EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTS----VPT 404
            T  +  ++T E  T +R + +  + +  E + +  +    +E    +   S++    VP 
Sbjct: 4858 TSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSSTETSTVPY 4917

Query: 405  KP----------TENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLA 454
            K           T+  S +S+  P P   T +  +    NT LS SP             
Sbjct: 4918 KELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSP------------- 4964

Query: 455  KISSILSSLTSVMKNTGVSPASRPSPGTPT-SPSNLTSGLKTPAPATTTSHNPLANILSK 513
                I++    +   T   P    S  T T  PSN T             H+ + +  S+
Sbjct: 4965 ----IMTESAEITITTQTGPHGATSQDTFTMDPSNTT--------PQAGIHSAMTHGFSQ 5012

Query: 514  VEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTI 573
            +++T  +++S + +  + ++P               P     ++  S  +SPA TT S I
Sbjct: 5013 LDVT--TLMSRIPQDVSWTSP---------------PSVDKTSSPSSFLSSPAMTTPSLI 5055

Query: 574  KGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTA 633
                LP         S   S     +++  T     +    P   ST+ K+ + S     
Sbjct: 5056 SS-TLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVT-SSLPNFSSTSDKILATSKDSKD 5113

Query: 634  THNTSPAAPPTEVTICQSS---EVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIP 690
            T    P+    E  +  ++   E   P L    T  +    +     G+P  S    ++P
Sbjct: 5114 TKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAPS---TSMP 5170

Query: 691  ILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTM 750
            +  S        S  ++ +R PT      +  T    E S       ++ K  + ++  +
Sbjct: 5171 VHGS--------SETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEV 5222

Query: 751  SLLSKIISPGSSTPSSTRS--PPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGME 808
            S      S   STP   +S  PP       PR  ++S+ T       + +    P +   
Sbjct: 5223 SSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKT--KSAEMTITTQASPPESAS 5280

Query: 809  RPSSLMDSSQEKFYPDTSFQEDEDYRDFEYS---GPPPSAMMNLEKKPAKSILKSSKLSD 865
              +  +D+S       T     + +   E +   G  P  +  +   P +     S L  
Sbjct: 5281 HSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMS 5340

Query: 866  T---TEYQPILSSYSHRAQEFGVK-SAFPPSVRA----LLDSSENCDRLSSSPGLFGAFS 917
            +   T   P+ S+         +  +A P SV      +L ++      SS P L    S
Sbjct: 5341 SPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNL---SS 5397

Query: 918  VRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSP 977
            +    P + +  + ++     + ++   ++  S +GH S  Q              L S 
Sbjct: 5398 ITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKS--QSSVLADSETSKATPLMST 5455

Query: 978  QNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSD 1037
             +TL   +    T  + +   + I T  T      L    R+ S  +         T   
Sbjct: 5456 TSTLGDTSVSTSTPNISQ--TNQIQTEPTASLSPRL----RESSTSEKTSSTTETNTAFS 5509

Query: 1038 GVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRR 1097
             V    +TQ S                T +SSS   + D      AP  + G  +    R
Sbjct: 5510 YVPTGAITQAS---------------RTEISSSRTSISDLDRPTIAPDISTGMIT----R 5550

Query: 1098 MSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSA-------SELAS 1150
            +   PI T  +           G  A+  G     TS + F  G  S        SE+ +
Sbjct: 5551 LFTSPIMTKSAEMTVTTQTTTPG--ATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITT 5608

Query: 1151 LGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNS-FNSTFEHHLPPSPL 1199
            L     G ++   T P +E +  F     S  S S  +ST    +P SPL
Sbjct: 5609 LRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPL 5658



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 105/483 (21%), Positives = 176/483 (36%), Gaps = 89/483 (18%)

Query: 312  TLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDM 371
            +LP  EE+   S S+ +P+ T +           S   T+    S++P PVT    +  +
Sbjct: 8551 SLPSVEEASSVSSSLSSPAMTST-----------SFFSTLPESISSSPHPVTALLTLGPV 8599

Query: 372  ELSDVEDDGSKIIVEDRKEKPAEKSAVS-----TSVPTKPTENISKASSCTPVPVTMTAT 426
            + +D+    S    E     P   S+ S     TS  TK  E I  +S+ TPV    T  
Sbjct: 8600 KTTDMLRTSS----EPETSSPPNLSSTSAEILATSEVTKDREKIHPSSN-TPVVNVGTV- 8653

Query: 427  PPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSP 486
                  +   LSPS                 S+L+ L +                 PTSP
Sbjct: 8654 ------IYKHLSPS-----------------SVLADLVTTK---------------PTSP 8675

Query: 487  SNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSV 546
               TS L   + +T+T   P   +          +    +  +T SA       S + + 
Sbjct: 8676 MATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTG 8735

Query: 547  TGNPVPASEAAS--QSTSASPANTTVS------TIKGRNLP----SSAQPFIPKSFNYSP 594
                V  +EA S  ++++  PA +T+S      TI   + P     SA+  I     +S 
Sbjct: 8736 ATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSG 8795

Query: 595  NSSTSEVSSTSASKASIGQSPGLPS-TTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSE 653
             SS    +  ++S+AS    PG  S  T + P + +    +      + P+  ++ ++S 
Sbjct: 8796 ASSQGTFTLDTSSRAS---WPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSP 8852

Query: 654  VSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
             S     S  TSPS        L   P  S  +  + + S         +   D    P 
Sbjct: 8853 PSSLVSLSAVTSPSP-------LYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPV 8905

Query: 714  STSIDNIDGTPVRDERSGTPTQD----EMMDKPTSSSVDTMSLLSKIIS--PGSSTPSST 767
            +TS  +++ T      +   T +    ++ +    + + T+S   +  S  PG   PS  
Sbjct: 8906 TTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKV 8965

Query: 768  RSP 770
             SP
Sbjct: 8966 TSP 8968



 Score = 38.1 bits (87), Expect = 0.063
 Identities = 55/235 (23%), Positives = 99/235 (42%), Gaps = 15/235 (6%)

Query: 406  PTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPN-LANVDLAKISS----IL 460
            P   I+   S TP  V+   TPP+ +  +     SP++  P+ +++     I S    + 
Sbjct: 5602 PHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPVT 5661

Query: 461  SSLTSVM-KNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATT---TSHNPLANILSKVEI 516
            + LTSV+   T V   + P P T +SP NL+S   T    TT   T+H    +       
Sbjct: 5662 ALLTSVLVTTTNVLGTTSPEPVT-SSPPNLSS--PTQERLTTYKDTAHTEAMHASMHTNT 5718

Query: 517  TPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGR 576
               ++ +++S  ++QS+      +S   S  G      + +  +++ +   T + T    
Sbjct: 5719 AVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTS 5778

Query: 577  NL-PSSAQPFIPKSFNYSPNSST--SEVSSTSASKASIGQSPGLPSTTFKLPSNS 628
            +L P        +  N    +ST  SEV +T+ ++ S  +      TT   P +S
Sbjct: 5779 SLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDHS 5833


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 183/810 (22%), Positives = 283/810 (34%), Gaps = 107/810 (13%)

Query: 393  AEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPA-LALPNLANV 451
            +E S    S P  PT  +S AS  T + V   +T    +P +T  + SPA    P L+  
Sbjct: 728  SEASTTFYSSPRSPTTTLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 786

Query: 452  DLAKISSIL----------SSLTSVMKNTGVSPASRPSPGTPT--SPSNLTSGLKTPA-- 497
                 SS            S+ TSV      +  SRP+    T  +  + TSGL   +  
Sbjct: 787  STTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 846

Query: 498  ----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPA 553
                PA+T +  P     + +     +  S+   T T+ +PA    S L+   T + +  
Sbjct: 847  FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSP 906

Query: 554  SEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQ 613
            S   + +   SP   ++S        S   P    S   + +S  SE SSTS S+     
Sbjct: 907  SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 966

Query: 614  SPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIH 673
            +   P +T      S   T +H++  +   TE T+   S  +    +  +T  S      
Sbjct: 967  TTAFPDST-TTSDLSQEPTTSHSSQGS---TEATLSPGSTTASSLGQQSTTFHSSPGDTE 1022

Query: 674  -NFLKGNPGFSGL-NLNIPILSSLGS-----------SAPSESHPSDFQRGPTSTSIDNI 720
               L  +   SGL   + P  SS GS           SA  +   + FQ  P+S+     
Sbjct: 1023 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS----- 1077

Query: 721  DGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES--Y 778
            D TP     +  P +         SS  T    +   + G S  S+T    PG   +  +
Sbjct: 1078 DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALF 1137

Query: 779  PRELSNSV----STYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYR 834
            P   + SV     T  P   GS      P  G    + L + S       T+F       
Sbjct: 1138 PTRSATSVLVGEPTTSPISSGSTETTALP--GSTTTAGLSEKS-------TTF------- 1181

Query: 835  DFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVR 894
               YS P         + P  ++  +S  S     +   S+ SH        +AFP S  
Sbjct: 1182 ---YSSP---------RSPDTTLSPASTTSSGVSEE---STTSHSRPGSTHTTAFPGST- 1225

Query: 895  ALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGH 954
             +   S+      SSPG        G+   S   P  +   S  +P S   +L    T  
Sbjct: 1226 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS--SPGSTETTLLPDNTTA 1283

Query: 955  LSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTIST--------TST 1006
              L +   P       H S  SP  TL +P G     G      S  S+        T+T
Sbjct: 1284 SGLLEASTP------VHSSTGSPHTTL-SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTT 1336

Query: 1007 IEFKNMLKNASRKPSD--DKHFGQA--------PSKGTPSDGVSLSNLTQPSLTATDQQQ 1056
              F  +   +   PS     HF  +         S    S  V+ +    P+ + T    
Sbjct: 1337 SAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 1396

Query: 1057 QEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGN 1116
            +E      +  S+  +  P+S+   G   E+   HS++   +S  P  T   +  P   +
Sbjct: 1397 EESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH 1456

Query: 1117 RGHGREASRVGWFDLSTSGSSFDNGPSSAS 1146
               G  A+       +TSG S ++  S +S
Sbjct: 1457 SSPGSIATTHFPESSTTSGRSEESTASHSS 1486



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 164/708 (23%), Positives = 264/708 (37%), Gaps = 100/708 (14%)

Query: 311  STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVED 370
            +TLP    SP  +PS+   S T   SP      + + SP   +    + E  T +     
Sbjct: 912  TTLPG---SPT-TPSLSEKSTTFYTSP---RSPDATLSPATTTSSGVSEESSTSHSQPGS 964

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPP-- 428
               +   D  +     D  ++P    +   S     +   + ASS      T  ++P   
Sbjct: 965  THTTAFPDSTT---TSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT 1021

Query: 429  ----LPKPVNTS---LSPSPALALPNLANVDLAKISSILSSL---TSVMKNTGVSPASRP 478
                LP    TS    + +P  +     +  L   SS  + L   ++  ++   S  + P
Sbjct: 1022 ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP 1081

Query: 479  SP-GTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQ 537
            SP GT  +P  +++   +   +T T+H   ++          ++ S+   T T   P   
Sbjct: 1082 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS 1141

Query: 538  GLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSS 597
              S L+   T +P+    + S  T+A P +TT + +  ++    + P  P +   SP S+
Sbjct: 1142 ATSVLVGEPTTSPI---SSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT-TLSPAST 1197

Query: 598  TS----EVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSE 653
            TS    E S+TS S+     +   P +T  +P  S   TA+H+ SP +  T+ T+   S 
Sbjct: 1198 TSSGVSEESTTSHSRPGSTHTTAFPGST-TMPGVSQESTASHS-SPGS--TDTTLSPGST 1253

Query: 654  VSKPKLESESTS--PSLEMKIHNFLKGNPGFSGL-NLNIPILSSLGSSAPSESHPSDFQR 710
             +   L  EST+   S        L  N   SGL   + P+ SS GS   + S      R
Sbjct: 1254 TAS-SLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR 1312

Query: 711  GPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPS---ST 767
               ST+            +S   ++D M   PT++S       +   SP SSTP+   S 
Sbjct: 1313 QGESTTF-----------QSWPSSKDTMPAPPTTTSAFVELSTTSHGSP-SSTPTTHFSA 1360

Query: 768  RSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSS----QEKFYP 823
             S   GR E      S+ V+T       + SP +  + G+   S+   SS    Q   +P
Sbjct: 1361 SSTTLGRSEESTTVHSSPVATAT-----TPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 1415

Query: 824  DTSFQE--DEDYRDFEYS-----GPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSY 876
            ++S      E+ R    S       PPS    L ++P      SS  S  T + P  S+ 
Sbjct: 1416 ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTS--YHSSPGSIATTHFPESSTT 1473

Query: 877  SHRAQEFGVKSAFPP----------------------------SVRALLDSSENCDRLSS 908
            S R++E     + P                             S+   L S+     LS+
Sbjct: 1474 SGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSA 1533

Query: 909  SPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLS 956
               +     + G       SPSP+    F    S      +STT H S
Sbjct: 1534 KSTILYTSDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTS 1581



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 232/1003 (23%), Positives = 350/1003 (34%), Gaps = 173/1003 (17%)

Query: 393  AEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPAL----ALPNL 448
            +E+S  S S P      +  A S TP  +   +TP    P+++    + AL      P L
Sbjct: 64   SEESKASHSSPDAMATTVLPAGS-TPSVLVGDSTP---SPISSGSMETTALPGSTTKPGL 119

Query: 449  ANVDLAKISSILSS----LTSVMKNTGVSPASRPSPGTPTSP-------SNLTSGLKTPA 497
            +       SS  S     L + M ++GVS  S  S   P S        S    GL   +
Sbjct: 120  SEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQES 179

Query: 498  PATTTSHNPLANILSKVEITPESI-------LSALSKTQTQSAPALQGLSSLLQSVTGNP 550
             A+ +S  P    LS    T  S+        S    T+T   P     S LL++    P
Sbjct: 180  TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA--SMP 237

Query: 551  VPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKAS 610
            V +S   S  T+ SPA +T      R   S+     P S +  P   T+  +    S  S
Sbjct: 238  VHSS-TRSPHTTLSPAGSTT-----RQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 291

Query: 611  IGQSPGLPSTTFKLPSNSLGF---TATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS 667
             G    +P+T     S + G    + T+++SP +  T+      S+ +  + E  +TS S
Sbjct: 292  HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGS--TQTMHFPESDTTSGRGEESTTSHS 349

Query: 668  LEMKIHNFLKGNPGFSGLNLNIPIL--SSLGSSAPSESHPSDFQRG-----PTSTSIDNI 720
                  + +   P  +   +  P    SS GS+A +    S    G       S S  + 
Sbjct: 350  ---STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 406

Query: 721  DGTPVRDERSGTPT-QDEMMDKPTSS-SVDTMSLLSKIISPGSSTPSSTRSPPPGRDESY 778
             GT V   RS T     E    P SS S++T +L     +PG S  S+T    P      
Sbjct: 407  TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP------ 460

Query: 779  PRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEY 838
                 +  +T  P    S    ++ +    RP S   ++    +PD++            
Sbjct: 461  ----RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTA----FPDSTTTPGLSRHSTTS 512

Query: 839  SGPPPSAMMNLEKKPAKSILKSSKLSDTTEY------QPILSSYSHRAQEFGVKSA---- 888
               P S    L   PA +         TT +         LS  S  A  FG +S     
Sbjct: 513  HSSPGSTDTTL--LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHS 570

Query: 889  ---------FPPSVRA--------LLDSSENCDRL------SSSPGLFGAFSVRGNEPGS 925
                     FP S  +         + SS    R       S+SPGL G  +     P S
Sbjct: 571  NPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 630

Query: 926  DR-SPSPSKNDSFFTPDSNHNSLSQSTTGHL---SLPQKQYPDSPHPVPH---RSLF--S 976
               +PSP        P +    + +STT H    S P   +P S     H    ++F  S
Sbjct: 631  THTTPSP--------PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 682

Query: 977  PQNTLAAP-TGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTP 1035
            P  +   P + H  TSG  +   S IS  ST E   +  + +     +       S  +P
Sbjct: 683  PDASGTTPSSAHSTTSGRGESTTSRISPGST-EITTLPGSTTTPGLSEASTTFYSSPRSP 741

Query: 1036 SDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEE--------KGAPIET 1087
            +  +S +++T   +       + +     + VS +    P  +EE        +G+   T
Sbjct: 742  TTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETT 801

Query: 1088 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLST----SGSSFDNGPS 1143
            +  HS +      EP  T    R           +++  G  + ST    S +S   G  
Sbjct: 802  VFPHSTTTSVHGEEP--TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 859

Query: 1144 SASELASLGG-----GGSGGLTGFKTAPYKERAPQF-QESVGSFRSNSFNSTFEHHLPPS 1197
            +    A LG        S G TG K +P +        ES  S  S S  ST    LP S
Sbjct: 860  ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS--STETTTLPGS 917

Query: 1198 PL-----EHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAH 1252
            P      E  T F   P  P +                  T  P+   S+  ++E++ +H
Sbjct: 918  PTTPSLSEKSTTFYTSPRSPDA------------------TLSPATTTSSGVSEESSTSH 959

Query: 1253 AAPPPPPGEHSGIPFP-----TPPPPPPPGEHSSSGGSGVPFS 1290
            +     PG      FP     +     P   HSS G +    S
Sbjct: 960  S----QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 998



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 86/398 (21%), Positives = 146/398 (36%), Gaps = 35/398 (8%)

Query: 323  SPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSK 382
            S +M   S   + S       + + SP   +  S  PE  T +      E + + D+ + 
Sbjct: 1224 STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA 1283

Query: 383  IIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTS-----L 437
              + +    P   S  S      P  + ++    T      ++   +P P  T+     L
Sbjct: 1284 SGLLEAST-PVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVEL 1342

Query: 438  SPSPALALPNLANVDLAKISSIL--SSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKT 495
            S +   +  +      +  S+ L  S  ++ + ++ V+ A+ PSP   T     TSGL  
Sbjct: 1343 STTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST-----TSGLVE 1397

Query: 496  PAPA-------TTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTG 548
             + A       T T H P ++  S    + ES  S  S T T S+P     S+L++    
Sbjct: 1398 ESTAYHSSPGSTQTMHFPESSTASGR--SEESRTSHSSTTHTISSPP-STTSALVEE--- 1451

Query: 549  NPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASK 608
               P S  +S  + A+      ST  GR+  S+A    P +   +P  +    S   A  
Sbjct: 1452 ---PTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAES 1508

Query: 609  ASIGQSPGLPSTTFKLPSNSLGFTA----THNTSPAAPPTEVTICQSSEVSKPKLESEST 664
             +   SPG   TT    + + G +A     + +     PT   I  S   +     S ST
Sbjct: 1509 TTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLFPASSST 1568

Query: 665  SPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE 702
            S   E         +P F+   ++   L +L    P +
Sbjct: 1569 SGLTEES--TTFHTSPSFTSTIVSTESLETLAPETPEK 1604


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 111/504 (22%), Positives = 167/504 (33%), Gaps = 103/504 (20%)

Query: 314 PDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMEL 373
           P P     P+P+   P+PT  + P       +  +PT   E    P P T          
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPKE----PAPTTP--------- 369

Query: 374 SDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCT---PVPVTMTATPPLP 430
                         ++  P      S + P +P    +K++  T   P P T  + P  P
Sbjct: 370 --------------KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415

Query: 431 KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLT 490
           K  + + +  PA   P                     K    +   +P+P TP  P+  T
Sbjct: 416 KEPSPTTTKEPAPTTP---------------------KEPAPTTPKKPAPTTPKEPAPTT 454

Query: 491 SGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP 550
              K PAP TT    P          TP+       K  T + P       L  +    P
Sbjct: 455 P--KEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP-----EKLAPTTPEKP 506

Query: 551 VPAS---------EAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEV 601
            P +         E  + +T   PA TT       N P    P  PK     P  +T + 
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA-APNTPKEPAPTTPKE----PAPTTPKE 561

Query: 602 SSTSASKASIGQSP-GLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE 660
            + +  K +   +P G   TT K P+ +   T          PT      S+   KP   
Sbjct: 562 PAPTTPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPT 618

Query: 661 S-ESTSPSLEMKIHNFLKGNP------GFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
           + + T+P+   +        P      G +   L  P  ++    AP E  P+   +GPT
Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPT 677

Query: 714 STSIDNIDGTPVRDERSGTPTQDEMMDK------------PTSSSVDTMSLLSKII---- 757
           ST+ D    T  ++    TP +                  PT+S V T +   +      
Sbjct: 678 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 737

Query: 758 SPGSSTPSSTRSPPPGRDESYPRE 781
           SP  STP  +  P P   E+ P+E
Sbjct: 738 SPDESTPELSAEPTPKALENSPKE 761



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 75/360 (20%), Positives = 132/360 (36%), Gaps = 38/360 (10%)

Query: 310 KSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPV-TDNRDV 368
           K+  P+  + P P+   + P+PT  + P      E + +    +  +   EP  T  +  
Sbjct: 536 KAAAPNTPKEPAPTTPKE-PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594

Query: 369 EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPP 428
              EL+      +K       +KPA  +   T+ PT P E  +  +   P P T   T P
Sbjct: 595 APKELAPTT---TKEPTSTTCDKPAPTTPKGTA-PTTPKEP-APTTPKEPAPTTPKGTAP 649

Query: 429 LP----------KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRP 478
                       KP    L+P+     P     D    ++   +  +  K    +   +P
Sbjct: 650 TTLKEPAPTTPKKPAPKELAPTTTKG-PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708

Query: 479 SPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQG 538
           +P TP +P   TS + TP    TT+  P     S  E TPE       K   +++P   G
Sbjct: 709 APTTPETPPPTTSEVSTP----TTTKEPTTIHKSPDESTPELSAEPTPKA-LENSPKEPG 763

Query: 539 LSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSST 598
           + +        P   + A  ++T      T  +T     +         K+      ++T
Sbjct: 764 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823

Query: 599 SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPK 658
           ++V+ST+             +T FK+ +       T   +P    T+ TI  +  ++KP+
Sbjct: 824 TQVTSTTTQ----------DTTPFKITT-----LKTTTLAPKVTTTKKTITTTEIMNKPE 868



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 80/380 (21%), Positives = 134/380 (35%), Gaps = 57/380 (15%)

Query: 322 PSPSMDAPSPTGSESPFQGMGGE---ESQSPTMESEKSATP--EPVTDNRDVEDMELSDV 376
           P PS+   S T  E+    +  E   E++  T  +++++T   E  T  ++ + +E +  
Sbjct: 126 PRPSLPPNSDTSKETSLT-VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 184

Query: 377 ED--DGSKIIVED----------------RKEKPAEKSAVSTSVPTKPTENISKASSCTP 418
           +D    SK++ +                 ++  P      +++ P +PT    K++  TP
Sbjct: 185 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 244

Query: 419 ---VPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAK--ISSILSSLTSVMKNTGVS 473
               P T  + P  PK    + +  PA   P        K    +   S  +  K    +
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304

Query: 474 PASRPSPGTPTSPSNLTSGLKTPA-----------PATTTSHNPLANILSKVEITPESIL 522
              +P+P TP  P+  T    TP            PA TT   P      K    P    
Sbjct: 305 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK----PAPTT 360

Query: 523 SALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSA 582
                  T   PA         +    P P +  ++ +T+  PA TT  T      P   
Sbjct: 361 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT--TKSAPTTPKEP 418

Query: 583 QPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPS-TTFKLPSNSLGFTATHNTSPAA 641
            P   K     P  +T +  + +  K     +P  P+ TT K P+     T T   +P  
Sbjct: 419 SPTTTK----EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP----TTTKKPAPTT 470

Query: 642 P--PTEVTICQSSEVSKPKL 659
           P  P   T  +++  +  KL
Sbjct: 471 PKEPAPTTPKETAPTTPKKL 490



 Score = 35.0 bits (79), Expect = 0.53
 Identities = 42/164 (25%), Positives = 59/164 (35%), Gaps = 17/164 (10%)

Query: 1142 PSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSP--L 1199
            P++  E A     G+   T  + AP   + P  +E   +      ++T +   P +P   
Sbjct: 564  PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623

Query: 1200 EHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPP-- 1257
               TP +  P  P    P  PK         APT L     + P  K+ A    AP    
Sbjct: 624  APTTPKEPAPTTPKEPAPTTPKG-------TAPTTLKEPAPTTP--KKPAPKELAPTTTK 674

Query: 1258 -PPGEHSGIPFPTPP---PPPPPGEHSSSGGSGVPFSTPPPPPP 1297
             P    S  P PT P    P  P E + +       +TP  PPP
Sbjct: 675  GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718



 Score = 34.7 bits (78), Expect = 0.69
 Identities = 73/344 (21%), Positives = 108/344 (31%), Gaps = 63/344 (18%)

Query: 963  PDSPHPVPHRSLFSPQNTLAAPTGH----PPTSGVEKVLASTISTTSTIEFKNMLKNASR 1018
            PD+     ++   SP+ T A P       PP S   K  + T++  +T+E K       +
Sbjct: 102  PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 161

Query: 1019 KPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDST 1078
              +D K         +  +  S+   +   L  T +   +   + ET      L  P   
Sbjct: 162  TSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE- 215

Query: 1079 EEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSF 1138
                 P  T     AS       P  T++S     K                   + ++ 
Sbjct: 216  -----PTPTTPKEPASTTPKEPTPT-TIKSAPTTPK-----------------EPAPTTT 252

Query: 1139 DNGPSSASELASLGGGGSGGLTGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPP 1196
             + P++  E A          T  + AP   KE AP   +      + S  +T +   P 
Sbjct: 253  KSAPTTPKEPAPT--------TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304

Query: 1197 SPLEHG--TPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            +P +    TP +  P  P    P  PK+        APT            KE A    A
Sbjct: 305  TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT----------PKEPA--PTA 352

Query: 1255 PPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPP 1298
            P  P       P PT P  P P           P  T P  P P
Sbjct: 353  PKKPAPTTPKEPAPTTPKEPAPTTTKE------PSPTTPKEPAP 390



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 147/774 (18%), Positives = 248/774 (32%), Gaps = 132/774 (17%)

Query: 554  SEAASQSTSASPANTTVSTIKGR-NLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIG 612
            S       S SP  TT   I  R +LP ++      S   +  ++     +T+ +K +  
Sbjct: 105  STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-- 162

Query: 613  QSPGLPSTTFKLPSNSLGFTATHNTSPAAP------PTEVTICQSSEVSKPKLESESTSP 666
             + G   TT    + S+  T+  + +P +       P   T  +   ++ PK E   T+P
Sbjct: 163  STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK-EPTPTTP 221

Query: 667  SLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTS-------TSIDN 719
                         P  +      P       + P E  P+  +  PT+       T+ + 
Sbjct: 222  K-----------EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 270

Query: 720  IDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDE--- 776
               TP    +   PT  +     T+ S  T        +P    P++ + P P   +   
Sbjct: 271  APTTP----KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 326

Query: 777  -SYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRD 835
             + P+E + +     P      +P          P     ++ ++  P T+ +E      
Sbjct: 327  PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT-KEPSPTTP 385

Query: 836  FEYSGPPPSAMMNLEKKPAKSILKSSKL-----SDTTEYQPILSSYSHRAQEFGVKSA-F 889
             E +     +     K+PA +  KS+       S TT  +P  ++    A     K A  
Sbjct: 386  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445

Query: 890  PPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQ 949
             P   A     E     +  P            P + + P+P+      T  +    L+ 
Sbjct: 446  TPKEPAPTTPKEPAPTTTKKPA-----------PTTPKEPAPTTPKE--TAPTTPKKLTP 492

Query: 950  STTGHLS--LPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLA-STISTTST 1006
            +T   L+   P+K  P +P  +   +   P  T    T   P     K  A +T    + 
Sbjct: 493  TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT----TPEEPAPTTPKAAAPNTPKEPAP 548

Query: 1007 IEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETR 1066
               K       ++P+       AP+  TP  G + + L +P+ T   +   +E     T+
Sbjct: 549  TTPKEPAPTTPKEPAPTTPKETAPT--TPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTK 605

Query: 1067 V-SSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASR 1125
              +S+  D P  T  KG    T             EP                       
Sbjct: 606  EPTSTTCDKPAPTTPKGTAPTT-----------PKEP----------------------- 631

Query: 1126 VGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNS 1185
                            P++  E A     G+   T  + AP   + P  +E   +     
Sbjct: 632  ---------------APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676

Query: 1186 FNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNP-F 1244
             ++T +   P +P E      +EP     AP  P K          PT   + ++S P  
Sbjct: 677  TSTTSDKPAPTTPKETAPTTPKEP-----APTTPKKPAPTTPETPPPT---TSEVSTPTT 728

Query: 1245 TKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPP 1298
            TKE    H +P     E S         P P    +S    GVP +  P    P
Sbjct: 729  TKEPTTIHKSPDESTPELSA-------EPTPKALENSPKEPGVPTTKTPAATKP 775



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 33/146 (22%), Positives = 46/146 (31%), Gaps = 20/146 (13%)

Query: 1168 KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVP--PKDHGG 1225
            KE AP  +E   +       +  +   P +P E      +EP   ++  P P  PK+   
Sbjct: 331  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390

Query: 1226 IFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGS 1285
              ++ APT         P       A   P  P    +  P PT P  P P         
Sbjct: 391  TTTKSAPT-----TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--------- 436

Query: 1286 GVPFSTPPPPPPPVDHSGVVPFPAPP 1311
                +TP  P P          P  P
Sbjct: 437  ----TTPKKPAPTTPKEPAPTTPKEP 458



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 6/124 (4%)

Query: 1195 PPSPLEHGTPFQREPVGPS-SAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHA 1253
            P +P E  +   +EP   +  + P  PK+     ++ APT     + +   TKE A    
Sbjct: 218  PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT--TPKEPAPTTTKEPAPTTP 275

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPP--PVDHSGVVP-FPAP 1310
              P P       P  T   P  P E + +       +TP  P P  P + +   P  PAP
Sbjct: 276  KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 335

Query: 1311 PLAE 1314
               E
Sbjct: 336  TTKE 339



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 40/173 (23%), Positives = 55/173 (31%), Gaps = 22/173 (12%)

Query: 1160 TGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHG--TPFQREPVGPSSA 1215
            T  K+AP   KE AP   +S  +       +T +   P +P E    TP +  P  P   
Sbjct: 391  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450

Query: 1216 PPVPPKDHGGIFSRD-----------------APTHLPSVDLSNPFTKEAALAHAAPPPP 1258
             P  PK+     ++                  APT    +  + P  K A      P P 
Sbjct: 451  APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPT 509

Query: 1259 PGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
              E      P  P P  P E + +       +TP  P P          P  P
Sbjct: 510  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 111/504 (22%), Positives = 167/504 (33%), Gaps = 103/504 (20%)

Query: 314 PDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMEL 373
           P P     P+P+   P+PT  + P       +  +PT   E    P P T          
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPKE----PAPTTP--------- 410

Query: 374 SDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCT---PVPVTMTATPPLP 430
                         ++  P      S + P +P    +K++  T   P P T  + P  P
Sbjct: 411 --------------KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456

Query: 431 KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLT 490
           K  + + +  PA   P                     K    +   +P+P TP  P+  T
Sbjct: 457 KEPSPTTTKEPAPTTP---------------------KEPAPTTPKKPAPTTPKEPAPTT 495

Query: 491 SGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP 550
              K PAP TT    P          TP+       K  T + P       L  +    P
Sbjct: 496 P--KEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP-----EKLAPTTPEKP 547

Query: 551 VPAS---------EAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEV 601
            P +         E  + +T   PA TT       N P    P  PK     P  +T + 
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA-APNTPKEPAPTTPKE----PAPTTPKE 602

Query: 602 SSTSASKASIGQSP-GLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE 660
            + +  K +   +P G   TT K P+ +   T          PT      S+   KP   
Sbjct: 603 PAPTTPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPT 659

Query: 661 S-ESTSPSLEMKIHNFLKGNP------GFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
           + + T+P+   +        P      G +   L  P  ++    AP E  P+   +GPT
Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPT 718

Query: 714 STSIDNIDGTPVRDERSGTPTQDEMMDK------------PTSSSVDTMSLLSKII---- 757
           ST+ D    T  ++    TP +                  PT+S V T +   +      
Sbjct: 719 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 778

Query: 758 SPGSSTPSSTRSPPPGRDESYPRE 781
           SP  STP  +  P P   E+ P+E
Sbjct: 779 SPDESTPELSAEPTPKALENSPKE 802



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 75/360 (20%), Positives = 132/360 (36%), Gaps = 38/360 (10%)

Query: 310 KSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPV-TDNRDV 368
           K+  P+  + P P+   + P+PT  + P      E + +    +  +   EP  T  +  
Sbjct: 577 KAAAPNTPKEPAPTTPKE-PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635

Query: 369 EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPP 428
              EL+      +K       +KPA  +   T+ PT P E  +  +   P P T   T P
Sbjct: 636 APKELAPTT---TKEPTSTTCDKPAPTTPKGTA-PTTPKEP-APTTPKEPAPTTPKGTAP 690

Query: 429 LP----------KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRP 478
                       KP    L+P+     P     D    ++   +  +  K    +   +P
Sbjct: 691 TTLKEPAPTTPKKPAPKELAPTTTKG-PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749

Query: 479 SPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQG 538
           +P TP +P   TS + TP    TT+  P     S  E TPE       K   +++P   G
Sbjct: 750 APTTPETPPPTTSEVSTP----TTTKEPTTIHKSPDESTPELSAEPTPKA-LENSPKEPG 804

Query: 539 LSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSST 598
           + +        P   + A  ++T      T  +T     +         K+      ++T
Sbjct: 805 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864

Query: 599 SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPK 658
           ++V+ST+             +T FK+ +       T   +P    T+ TI  +  ++KP+
Sbjct: 865 TQVTSTTTQ----------DTTPFKITT-----LKTTTLAPKVTTTKKTITTTEIMNKPE 909



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 80/380 (21%), Positives = 134/380 (35%), Gaps = 57/380 (15%)

Query: 322 PSPSMDAPSPTGSESPFQGMGGE---ESQSPTMESEKSATP--EPVTDNRDVEDMELSDV 376
           P PS+   S T  E+    +  E   E++  T  +++++T   E  T  ++ + +E +  
Sbjct: 167 PRPSLPPNSDTSKETSLT-VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 225

Query: 377 ED--DGSKIIVED----------------RKEKPAEKSAVSTSVPTKPTENISKASSCTP 418
           +D    SK++ +                 ++  P      +++ P +PT    K++  TP
Sbjct: 226 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 285

Query: 419 ---VPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAK--ISSILSSLTSVMKNTGVS 473
               P T  + P  PK    + +  PA   P        K    +   S  +  K    +
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345

Query: 474 PASRPSPGTPTSPSNLTSGLKTPA-----------PATTTSHNPLANILSKVEITPESIL 522
              +P+P TP  P+  T    TP            PA TT   P      K    P    
Sbjct: 346 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK----PAPTT 401

Query: 523 SALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSA 582
                  T   PA         +    P P +  ++ +T+  PA TT  T      P   
Sbjct: 402 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT--TKSAPTTPKEP 459

Query: 583 QPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPS-TTFKLPSNSLGFTATHNTSPAA 641
            P   K     P  +T +  + +  K     +P  P+ TT K P+     T T   +P  
Sbjct: 460 SPTTTK----EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP----TTTKKPAPTT 511

Query: 642 P--PTEVTICQSSEVSKPKL 659
           P  P   T  +++  +  KL
Sbjct: 512 PKEPAPTTPKETAPTTPKKL 531



 Score = 35.0 bits (79), Expect = 0.53
 Identities = 42/164 (25%), Positives = 59/164 (35%), Gaps = 17/164 (10%)

Query: 1142 PSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSP--L 1199
            P++  E A     G+   T  + AP   + P  +E   +      ++T +   P +P   
Sbjct: 605  PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664

Query: 1200 EHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPP-- 1257
               TP +  P  P    P  PK         APT L     + P  K+ A    AP    
Sbjct: 665  APTTPKEPAPTTPKEPAPTTPKG-------TAPTTLKEPAPTTP--KKPAPKELAPTTTK 715

Query: 1258 -PPGEHSGIPFPTPP---PPPPPGEHSSSGGSGVPFSTPPPPPP 1297
             P    S  P PT P    P  P E + +       +TP  PPP
Sbjct: 716  GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759



 Score = 34.7 bits (78), Expect = 0.69
 Identities = 73/344 (21%), Positives = 108/344 (31%), Gaps = 63/344 (18%)

Query: 963  PDSPHPVPHRSLFSPQNTLAAPTGH----PPTSGVEKVLASTISTTSTIEFKNMLKNASR 1018
            PD+     ++   SP+ T A P       PP S   K  + T++  +T+E K       +
Sbjct: 143  PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 202

Query: 1019 KPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDST 1078
              +D K         +  +  S+   +   L  T +   +   + ET      L  P   
Sbjct: 203  TSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE- 256

Query: 1079 EEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSF 1138
                 P  T     AS       P  T++S     K                   + ++ 
Sbjct: 257  -----PTPTTPKEPASTTPKEPTPT-TIKSAPTTPK-----------------EPAPTTT 293

Query: 1139 DNGPSSASELASLGGGGSGGLTGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPP 1196
             + P++  E A          T  + AP   KE AP   +      + S  +T +   P 
Sbjct: 294  KSAPTTPKEPAPT--------TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345

Query: 1197 SPLEHG--TPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            +P +    TP +  P  P    P  PK+        APT            KE A    A
Sbjct: 346  TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT----------PKEPA--PTA 393

Query: 1255 PPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPP 1298
            P  P       P PT P  P P           P  T P  P P
Sbjct: 394  PKKPAPTTPKEPAPTTPKEPAPTTTKE------PSPTTPKEPAP 431



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 147/774 (18%), Positives = 248/774 (32%), Gaps = 132/774 (17%)

Query: 554  SEAASQSTSASPANTTVSTIKGR-NLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIG 612
            S       S SP  TT   I  R +LP ++      S   +  ++     +T+ +K +  
Sbjct: 146  STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-- 203

Query: 613  QSPGLPSTTFKLPSNSLGFTATHNTSPAAP------PTEVTICQSSEVSKPKLESESTSP 666
             + G   TT    + S+  T+  + +P +       P   T  +   ++ PK E   T+P
Sbjct: 204  STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK-EPTPTTP 262

Query: 667  SLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTS-------TSIDN 719
                         P  +      P       + P E  P+  +  PT+       T+ + 
Sbjct: 263  K-----------EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 311

Query: 720  IDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDE--- 776
               TP    +   PT  +     T+ S  T        +P    P++ + P P   +   
Sbjct: 312  APTTP----KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 367

Query: 777  -SYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRD 835
             + P+E + +     P      +P          P     ++ ++  P T+ +E      
Sbjct: 368  PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT-KEPSPTTP 426

Query: 836  FEYSGPPPSAMMNLEKKPAKSILKSSKL-----SDTTEYQPILSSYSHRAQEFGVKSA-F 889
             E +     +     K+PA +  KS+       S TT  +P  ++    A     K A  
Sbjct: 427  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486

Query: 890  PPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQ 949
             P   A     E     +  P            P + + P+P+      T  +    L+ 
Sbjct: 487  TPKEPAPTTPKEPAPTTTKKPA-----------PTTPKEPAPTTPKE--TAPTTPKKLTP 533

Query: 950  STTGHLS--LPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLA-STISTTST 1006
            +T   L+   P+K  P +P  +   +   P  T    T   P     K  A +T    + 
Sbjct: 534  TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT----TPEEPAPTTPKAAAPNTPKEPAP 589

Query: 1007 IEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETR 1066
               K       ++P+       AP+  TP  G + + L +P+ T   +   +E     T+
Sbjct: 590  TTPKEPAPTTPKEPAPTTPKETAPT--TPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTK 646

Query: 1067 V-SSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASR 1125
              +S+  D P  T  KG    T             EP                       
Sbjct: 647  EPTSTTCDKPAPTTPKGTAPTT-----------PKEP----------------------- 672

Query: 1126 VGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNS 1185
                            P++  E A     G+   T  + AP   + P  +E   +     
Sbjct: 673  ---------------APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717

Query: 1186 FNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNP-F 1244
             ++T +   P +P E      +EP     AP  P K          PT   + ++S P  
Sbjct: 718  TSTTSDKPAPTTPKETAPTTPKEP-----APTTPKKPAPTTPETPPPT---TSEVSTPTT 769

Query: 1245 TKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPP 1298
            TKE    H +P     E S         P P    +S    GVP +  P    P
Sbjct: 770  TKEPTTIHKSPDESTPELSA-------EPTPKALENSPKEPGVPTTKTPAATKP 816



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 33/146 (22%), Positives = 46/146 (31%), Gaps = 20/146 (13%)

Query: 1168 KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVP--PKDHGG 1225
            KE AP  +E   +       +  +   P +P E      +EP   ++  P P  PK+   
Sbjct: 372  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431

Query: 1226 IFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGS 1285
              ++ APT         P       A   P  P    +  P PT P  P P         
Sbjct: 432  TTTKSAPT-----TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--------- 477

Query: 1286 GVPFSTPPPPPPPVDHSGVVPFPAPP 1311
                +TP  P P          P  P
Sbjct: 478  ----TTPKKPAPTTPKEPAPTTPKEP 499



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 6/124 (4%)

Query: 1195 PPSPLEHGTPFQREPVGPS-SAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHA 1253
            P +P E  +   +EP   +  + P  PK+     ++ APT     + +   TKE A    
Sbjct: 259  PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT--TPKEPAPTTTKEPAPTTP 316

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPP--PVDHSGVVP-FPAP 1310
              P P       P  T   P  P E + +       +TP  P P  P + +   P  PAP
Sbjct: 317  KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 376

Query: 1311 PLAE 1314
               E
Sbjct: 377  TTKE 380



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 40/173 (23%), Positives = 55/173 (31%), Gaps = 22/173 (12%)

Query: 1160 TGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHG--TPFQREPVGPSSA 1215
            T  K+AP   KE AP   +S  +       +T +   P +P E    TP +  P  P   
Sbjct: 432  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491

Query: 1216 PPVPPKDHGGIFSRD-----------------APTHLPSVDLSNPFTKEAALAHAAPPPP 1258
             P  PK+     ++                  APT    +  + P  K A      P P 
Sbjct: 492  APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPT 550

Query: 1259 PGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
              E      P  P P  P E + +       +TP  P P          P  P
Sbjct: 551  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 111/504 (22%), Positives = 167/504 (33%), Gaps = 103/504 (20%)

Query: 314 PDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMEL 373
           P P     P+P+   P+PT  + P       +  +PT   E    P P T          
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPKE----PAPTTP--------- 462

Query: 374 SDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCT---PVPVTMTATPPLP 430
                         ++  P      S + P +P    +K++  T   P P T  + P  P
Sbjct: 463 --------------KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508

Query: 431 KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLT 490
           K  + + +  PA   P                     K    +   +P+P TP  P+  T
Sbjct: 509 KEPSPTTTKEPAPTTP---------------------KEPAPTTPKKPAPTTPKEPAPTT 547

Query: 491 SGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP 550
              K PAP TT    P          TP+       K  T + P       L  +    P
Sbjct: 548 P--KEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP-----EKLAPTTPEKP 599

Query: 551 VPAS---------EAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEV 601
            P +         E  + +T   PA TT       N P    P  PK     P  +T + 
Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA-APNTPKEPAPTTPKE----PAPTTPKE 654

Query: 602 SSTSASKASIGQSP-GLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE 660
            + +  K +   +P G   TT K P+ +   T          PT      S+   KP   
Sbjct: 655 PAPTTPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPT 711

Query: 661 S-ESTSPSLEMKIHNFLKGNP------GFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
           + + T+P+   +        P      G +   L  P  ++    AP E  P+   +GPT
Sbjct: 712 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPT 770

Query: 714 STSIDNIDGTPVRDERSGTPTQDEMMDK------------PTSSSVDTMSLLSKII---- 757
           ST+ D    T  ++    TP +                  PT+S V T +   +      
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 830

Query: 758 SPGSSTPSSTRSPPPGRDESYPRE 781
           SP  STP  +  P P   E+ P+E
Sbjct: 831 SPDESTPELSAEPTPKALENSPKE 854



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 161/840 (19%), Positives = 269/840 (32%), Gaps = 138/840 (16%)

Query: 279  EAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPF 338
            +AQ K+       Y++F   V+N        K+  P      + S +  +P P   +   
Sbjct: 46   DAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTK 105

Query: 339  QGMGGEE-----SQSPTMESEKSATPEPVTDN-RDVEDMELSDVEDD-GSKIIVEDR--- 388
            + +  EE     S S   ES  S++    +   R ++  + S    +   K+ V+D    
Sbjct: 106  KVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKN 165

Query: 389  --KEKPAEKSAV-------------STSVPTKPTENISKASSCTPVPVTMTATPPLPKPV 433
              K+KP  K  V               + P   T   +K S+   +       P    P 
Sbjct: 166  RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 225

Query: 434  NTSLSPSPALALPNLANV-----------------------------------DLAKISS 458
            N+  S   +L +     V                                   DLA  S 
Sbjct: 226  NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 285

Query: 459  ILSSLTSVMKNTGVSPA-SRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEIT 517
            +L+  T   + T   PA + P   TPT+P           PA+TT   P    +     T
Sbjct: 286  VLAKPTPKAETTTKGPALTTPKEPTPTTPKE---------PASTTPKEPTPTTIKSAPTT 336

Query: 518  PESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPAS-EAASQSTSASPANTTVSTIKGR 576
            P+      + T T+SAP          + T  P P + +  + +T+  PA TT  T    
Sbjct: 337  PKE----PAPTTTKSAPTTP--KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT--TKSAP 388

Query: 577  NLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHN 636
              P    P  PK     P  +T +  + +  K     +P  P+ T K P+     T    
Sbjct: 389  TTPKEPAPTTPK----KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP----TTPKE 440

Query: 637  TSPAAPPTEV-TICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSL 695
             +P AP     T  +    + PK  + +T+              P  +      P  +  
Sbjct: 441  PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK------------EPSPTTPKEPAPTTTKS 488

Query: 696  GSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSK 755
              +   E  P+  +  PT+      + +P   +     T  E           T      
Sbjct: 489  APTTTKEPAPTTTKSAPTTPK----EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544

Query: 756  IISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMD 815
              +P    P++T+ P P   +          +   P  L   +P K      E+P+    
Sbjct: 545  PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA---P 601

Query: 816  SSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSS 875
            ++ E+  P T  +      +      P +A  N  K+PA +  K    + TT  +P  ++
Sbjct: 602  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTT 659

Query: 876  YSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKND 935
                A          P   A     E        P               + +P+ +K  
Sbjct: 660  PKETAPT-------TPKGTAPTTLKEPAPTTPKKPA------------PKELAPTTTKEP 700

Query: 936  SFFTPDSNHNSLSQSTTGHLSLPQKQYPDSP-HPVPHRSLFSPQNTLAAPTGHPPTSGVE 994
            +  T D    +  + T    + P++  P +P  P P     +   TL  P    P     
Sbjct: 701  TSTTCDKPAPTTPKGTAP--TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758

Query: 995  KVLASTIS---TTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTA 1051
            K LA T +   T++T +           P+  K     P+  TP      +  T P  T+
Sbjct: 759  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKPAPTTPETPPPTTS 814



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 109/530 (20%), Positives = 182/530 (34%), Gaps = 74/530 (13%)

Query: 169 KSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLK 228
           KS T  +PK   K K      S+ + EE   +  SE+Q        S+      S+ T++
Sbjct: 89  KSTTKRSPKPPNKKKTKKVIESEEITEE---HSVSENQESSSSSSSSS------SSSTIR 139

Query: 229 CLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVV 288
            +K      K S    E   KL+   N  ++  K        ++ AG   +    + KV 
Sbjct: 140 KIKSS----KNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG--DFKVT 193

Query: 289 ANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQS 348
                T  +   +   K+   K   P P   P    S +       E+        E++ 
Sbjct: 194 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV------ETKE 247

Query: 349 PTMESEKSATP--EPVTDNRDVEDMELSDVED--DGSKIIVED----------------R 388
            T  +++++T   E  T  ++ + +E +  +D    SK++ +                 +
Sbjct: 248 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 307

Query: 389 KEKPAEKSAVSTSVPTKPTENISKASSCTP---VPVTMTATPPLPKPVNTSLSPSPALAL 445
           +  P      +++ P +PT    K++  TP    P T  + P  PK    + +  PA   
Sbjct: 308 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367

Query: 446 PNLANVDLAK--ISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPA------ 497
           P        K    +   S  +  K    +   +P+P TP  P+  T    TP       
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427

Query: 498 -----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVP 552
                PA TT   P      K    P           T   PA         +    P P
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKK----PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483

Query: 553 ASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIG 612
            +  ++ +T+  PA TT  T      P    P   K     P  +T +  + +  K    
Sbjct: 484 TTTKSAPTTTKEPAPTT--TKSAPTTPKEPSPTTTK----EPAPTTPKEPAPTTPKKPAP 537

Query: 613 QSPGLPS-TTFKLPSNSLGFTATHNTSPAAP--PTEVTICQSSEVSKPKL 659
            +P  P+ TT K P+     T T   +P  P  P   T  +++  +  KL
Sbjct: 538 TTPKEPAPTTPKEPAP----TTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 75/360 (20%), Positives = 132/360 (36%), Gaps = 38/360 (10%)

Query: 310 KSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPV-TDNRDV 368
           K+  P+  + P P+   + P+PT  + P      E + +    +  +   EP  T  +  
Sbjct: 629 KAAAPNTPKEPAPTTPKE-PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687

Query: 369 EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPP 428
              EL+      +K       +KPA  +   T+ PT P E  +  +   P P T   T P
Sbjct: 688 APKELAPTT---TKEPTSTTCDKPAPTTPKGTA-PTTPKEP-APTTPKEPAPTTPKGTAP 742

Query: 429 LP----------KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRP 478
                       KP    L+P+     P     D    ++   +  +  K    +   +P
Sbjct: 743 TTLKEPAPTTPKKPAPKELAPTTTKG-PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801

Query: 479 SPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQG 538
           +P TP +P   TS + TP    TT+  P     S  E TPE       K   +++P   G
Sbjct: 802 APTTPETPPPTTSEVSTP----TTTKEPTTIHKSPDESTPELSAEPTPKA-LENSPKEPG 856

Query: 539 LSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSST 598
           + +        P   + A  ++T      T  +T     +         K+      ++T
Sbjct: 857 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916

Query: 599 SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPK 658
           ++V+ST+             +T FK+ +       T   +P    T+ TI  +  ++KP+
Sbjct: 917 TQVTSTTTQ----------DTTPFKITT-----LKTTTLAPKVTTTKKTITTTEIMNKPE 961



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 165/855 (19%), Positives = 269/855 (31%), Gaps = 141/855 (16%)

Query: 473  SPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQS 532
            +P S PS      PS  +  +K+    T  S  P     +K  I  E I    S ++ Q 
Sbjct: 68   NPTSPPSSKKAPPPSGASQTIKS---TTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124

Query: 533  APALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNY 592
            + +    SS   ++       + AA++              + +  P+   P + ++ + 
Sbjct: 125  SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184

Query: 593  SPNS----STSEVSSTSASKAS----------IGQSPGLPSTTFKLPSNSLGFTATHNTS 638
              N     +T + S+T  +K S          I   P LP  +      SL  T    T+
Sbjct: 185  LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL--TVNKETT 242

Query: 639  PAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSS 698
                 T  T  Q+S   K K  S   + S+E                           +S
Sbjct: 243  VETKETTTTNKQTSTDGKEKTTSAKETQSIEK--------------------------TS 276

Query: 699  APSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIIS 758
            A   +  S     PT  +     G  +   +  TPT  +   +P S++            
Sbjct: 277  AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK---EPASTT------------ 321

Query: 759  PGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQ 818
            P   TP++ +S P    E  P    ++ +T +       +P          P     ++ 
Sbjct: 322  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-----EPAPTTTKEPAPTTPKEPAPTTT 376

Query: 819  EKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSH 878
            ++  P T+       ++     P P+      KKPA +  K    + TT  +P  ++   
Sbjct: 377  KEPAPTTTKSAPTTPKE-----PAPTT----PKKPAPTTPKEP--APTTPKEPTPTTPKE 425

Query: 879  RAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPS--KNDS 936
             A      +   P   A     +        P            P + + P+P+  K  S
Sbjct: 426  PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA-----------PTTPKEPAPTTTKEPS 474

Query: 937  FFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLA-APTG--HPPTSGV 993
              TP     + ++S       P      S    P     SP  T   APT    P  +  
Sbjct: 475  PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTP 532

Query: 994  EKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPS---KGTPSDGVSLSNLTQPSLT 1050
            +K   +T    +    K      ++KP+       AP+   +  P+    L+  T   L 
Sbjct: 533  KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 592

Query: 1051 ATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIR 1110
             T  ++       E   ++     P + EE   P  T    +A N      P    E   
Sbjct: 593  PTTPEKPAPTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPAPTTPKEPAP 649

Query: 1111 VPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKER 1170
               K                        +  P++  E A     G+   T  + AP   +
Sbjct: 650  TTPK------------------------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685

Query: 1171 APQFQESVGSFRSNSFNSTFEHHLPPSP--LEHGTPFQREPVGPSSAPPVPPKDHGGIFS 1228
             P  +E   +      ++T +   P +P      TP +  P  P    P  PK       
Sbjct: 686  KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------ 739

Query: 1229 RDAPTHLPSVDLSNPFTKEAALAHAAPPP---PPGEHSGIPFPTPP---PPPPPGEHSSS 1282
              APT L     + P  K+ A    AP     P    S  P PT P    P  P E + +
Sbjct: 740  -TAPTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 796

Query: 1283 GGSGVPFSTPPPPPP 1297
                   +TP  PPP
Sbjct: 797  TPKKPAPTTPETPPP 811



 Score = 34.7 bits (78), Expect = 0.69
 Identities = 73/344 (21%), Positives = 108/344 (31%), Gaps = 63/344 (18%)

Query: 963  PDSPHPVPHRSLFSPQNTLAAPTGH----PPTSGVEKVLASTISTTSTIEFKNMLKNASR 1018
            PD+     ++   SP+ T A P       PP S   K  + T++  +T+E K       +
Sbjct: 195  PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 254

Query: 1019 KPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDST 1078
              +D K         +  +  S+   +   L  T +   +   + ET      L  P   
Sbjct: 255  TSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE- 308

Query: 1079 EEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSF 1138
                 P  T     AS       P  T++S     K                   + ++ 
Sbjct: 309  -----PTPTTPKEPASTTPKEPTPT-TIKSAPTTPK-----------------EPAPTTT 345

Query: 1139 DNGPSSASELASLGGGGSGGLTGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPP 1196
             + P++  E A          T  + AP   KE AP   +      + S  +T +   P 
Sbjct: 346  KSAPTTPKEPAPT--------TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397

Query: 1197 SPLEHG--TPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            +P +    TP +  P  P    P  PK+        APT            KE A    A
Sbjct: 398  TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT----------PKEPA--PTA 445

Query: 1255 PPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPP 1298
            P  P       P PT P  P P           P  T P  P P
Sbjct: 446  PKKPAPTTPKEPAPTTPKEPAPTTTKE------PSPTTPKEPAP 483



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 33/146 (22%), Positives = 46/146 (31%), Gaps = 20/146 (13%)

Query: 1168 KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVP--PKDHGG 1225
            KE AP  +E   +       +  +   P +P E      +EP   ++  P P  PK+   
Sbjct: 424  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483

Query: 1226 IFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGS 1285
              ++ APT         P       A   P  P    +  P PT P  P P         
Sbjct: 484  TTTKSAPT-----TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--------- 529

Query: 1286 GVPFSTPPPPPPPVDHSGVVPFPAPP 1311
                +TP  P P          P  P
Sbjct: 530  ----TTPKKPAPTTPKEPAPTTPKEP 551



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 6/124 (4%)

Query: 1195 PPSPLEHGTPFQREPVGPS-SAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHA 1253
            P +P E  +   +EP   +  + P  PK+     ++ APT     + +   TKE A    
Sbjct: 311  PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT--TPKEPAPTTTKEPAPTTP 368

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPP--PVDHSGVVP-FPAP 1310
              P P       P  T   P  P E + +       +TP  P P  P + +   P  PAP
Sbjct: 369  KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 428

Query: 1311 PLAE 1314
               E
Sbjct: 429  TTKE 432



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 40/173 (23%), Positives = 55/173 (31%), Gaps = 22/173 (12%)

Query: 1160 TGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHG--TPFQREPVGPSSA 1215
            T  K+AP   KE AP   +S  +       +T +   P +P E    TP +  P  P   
Sbjct: 484  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543

Query: 1216 PPVPPKDHGGIFSRD-----------------APTHLPSVDLSNPFTKEAALAHAAPPPP 1258
             P  PK+     ++                  APT    +  + P  K A      P P 
Sbjct: 544  APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPT 602

Query: 1259 PGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
              E      P  P P  P E + +       +TP  P P          P  P
Sbjct: 603  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 111/504 (22%), Positives = 167/504 (33%), Gaps = 103/504 (20%)

Query: 314 PDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMEL 373
           P P     P+P+   P+PT  + P       +  +PT   E    P P T          
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPKE----PAPTTP--------- 503

Query: 374 SDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCT---PVPVTMTATPPLP 430
                         ++  P      S + P +P    +K++  T   P P T  + P  P
Sbjct: 504 --------------KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549

Query: 431 KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLT 490
           K  + + +  PA   P                     K    +   +P+P TP  P+  T
Sbjct: 550 KEPSPTTTKEPAPTTP---------------------KEPAPTTPKKPAPTTPKEPAPTT 588

Query: 491 SGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP 550
              K PAP TT    P          TP+       K  T + P       L  +    P
Sbjct: 589 P--KEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTP-----EKLAPTTPEKP 640

Query: 551 VPAS---------EAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEV 601
            P +         E  + +T   PA TT       N P    P  PK     P  +T + 
Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAA-APNTPKEPAPTTPKE----PAPTTPKE 695

Query: 602 SSTSASKASIGQSP-GLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLE 660
            + +  K +   +P G   TT K P+ +   T          PT      S+   KP   
Sbjct: 696 PAPTTPKETAPTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPT 752

Query: 661 S-ESTSPSLEMKIHNFLKGNP------GFSGLNLNIPILSSLGSSAPSESHPSDFQRGPT 713
           + + T+P+   +        P      G +   L  P  ++    AP E  P+   +GPT
Sbjct: 753 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPT 811

Query: 714 STSIDNIDGTPVRDERSGTPTQDEMMDK------------PTSSSVDTMSLLSKII---- 757
           ST+ D    T  ++    TP +                  PT+S V T +   +      
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 871

Query: 758 SPGSSTPSSTRSPPPGRDESYPRE 781
           SP  STP  +  P P   E+ P+E
Sbjct: 872 SPDESTPELSAEPTPKALENSPKE 895



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 161/840 (19%), Positives = 269/840 (32%), Gaps = 138/840 (16%)

Query: 279  EAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPF 338
            +AQ K+       Y++F   V+N        K+  P      + S +  +P P   +   
Sbjct: 87   DAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTK 146

Query: 339  QGMGGEE-----SQSPTMESEKSATPEPVTDN-RDVEDMELSDVEDD-GSKIIVEDR--- 388
            + +  EE     S S   ES  S++    +   R ++  + S    +   K+ V+D    
Sbjct: 147  KVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKN 206

Query: 389  --KEKPAEKSAV-------------STSVPTKPTENISKASSCTPVPVTMTATPPLPKPV 433
              K+KP  K  V               + P   T   +K S+   +       P    P 
Sbjct: 207  RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 266

Query: 434  NTSLSPSPALALPNLANV-----------------------------------DLAKISS 458
            N+  S   +L +     V                                   DLA  S 
Sbjct: 267  NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 326

Query: 459  ILSSLTSVMKNTGVSPA-SRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEIT 517
            +L+  T   + T   PA + P   TPT+P           PA+TT   P    +     T
Sbjct: 327  VLAKPTPKAETTTKGPALTTPKEPTPTTPKE---------PASTTPKEPTPTTIKSAPTT 377

Query: 518  PESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPAS-EAASQSTSASPANTTVSTIKGR 576
            P+      + T T+SAP          + T  P P + +  + +T+  PA TT  T    
Sbjct: 378  PKE----PAPTTTKSAPTTP--KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT--TKSAP 429

Query: 577  NLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHN 636
              P    P  PK     P  +T +  + +  K     +P  P+ T K P+     T    
Sbjct: 430  TTPKEPAPTTPK----KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP----TTPKE 481

Query: 637  TSPAAPPTEV-TICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSL 695
             +P AP     T  +    + PK  + +T+              P  +      P  +  
Sbjct: 482  PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK------------EPSPTTPKEPAPTTTKS 529

Query: 696  GSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSK 755
              +   E  P+  +  PT+      + +P   +     T  E           T      
Sbjct: 530  APTTTKEPAPTTTKSAPTTPK----EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585

Query: 756  IISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMD 815
              +P    P++T+ P P   +          +   P  L   +P K      E+P+    
Sbjct: 586  PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA---P 642

Query: 816  SSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSS 875
            ++ E+  P T  +      +      P +A  N  K+PA +  K    + TT  +P  ++
Sbjct: 643  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTT 700

Query: 876  YSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKND 935
                A          P   A     E        P               + +P+ +K  
Sbjct: 701  PKETAPT-------TPKGTAPTTLKEPAPTTPKKPA------------PKELAPTTTKEP 741

Query: 936  SFFTPDSNHNSLSQSTTGHLSLPQKQYPDSP-HPVPHRSLFSPQNTLAAPTGHPPTSGVE 994
            +  T D    +  + T    + P++  P +P  P P     +   TL  P    P     
Sbjct: 742  TSTTCDKPAPTTPKGTAP--TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799

Query: 995  KVLASTIS---TTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTA 1051
            K LA T +   T++T +           P+  K     P+  TP      +  T P  T+
Sbjct: 800  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE----PAPTTPKKPAPTTPETPPPTTS 855



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 109/530 (20%), Positives = 182/530 (34%), Gaps = 74/530 (13%)

Query: 169 KSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLK 228
           KS T  +PK   K K      S+ + EE   +  SE+Q        S+      S+ T++
Sbjct: 130 KSTTKRSPKPPNKKKTKKVIESEEITEE---HSVSENQESSSSSSSSS------SSSTIR 180

Query: 229 CLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVV 288
            +K      K S    E   KL+   N  ++  K        ++ AG   +    + KV 
Sbjct: 181 KIKSS----KNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG--DFKVT 234

Query: 289 ANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQS 348
                T  +   +   K+   K   P P   P    S +       E+        E++ 
Sbjct: 235 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV------ETKE 288

Query: 349 PTMESEKSATP--EPVTDNRDVEDMELSDVED--DGSKIIVED----------------R 388
            T  +++++T   E  T  ++ + +E +  +D    SK++ +                 +
Sbjct: 289 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 348

Query: 389 KEKPAEKSAVSTSVPTKPTENISKASSCTP---VPVTMTATPPLPKPVNTSLSPSPALAL 445
           +  P      +++ P +PT    K++  TP    P T  + P  PK    + +  PA   
Sbjct: 349 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408

Query: 446 PNLANVDLAK--ISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPA------ 497
           P        K    +   S  +  K    +   +P+P TP  P+  T    TP       
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468

Query: 498 -----PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVP 552
                PA TT   P      K    P           T   PA         +    P P
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKK----PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524

Query: 553 ASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIG 612
            +  ++ +T+  PA TT  T      P    P   K     P  +T +  + +  K    
Sbjct: 525 TTTKSAPTTTKEPAPTT--TKSAPTTPKEPSPTTTK----EPAPTTPKEPAPTTPKKPAP 578

Query: 613 QSPGLPS-TTFKLPSNSLGFTATHNTSPAAP--PTEVTICQSSEVSKPKL 659
            +P  P+ TT K P+     T T   +P  P  P   T  +++  +  KL
Sbjct: 579 TTPKEPAPTTPKEPAP----TTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 75/360 (20%), Positives = 132/360 (36%), Gaps = 38/360 (10%)

Query: 310  KSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPV-TDNRDV 368
            K+  P+  + P P+   + P+PT  + P      E + +    +  +   EP  T  +  
Sbjct: 670  KAAAPNTPKEPAPTTPKE-PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728

Query: 369  EDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPP 428
               EL+      +K       +KPA  +   T+ PT P E  +  +   P P T   T P
Sbjct: 729  APKELAPTT---TKEPTSTTCDKPAPTTPKGTA-PTTPKEP-APTTPKEPAPTTPKGTAP 783

Query: 429  LP----------KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRP 478
                        KP    L+P+     P     D    ++   +  +  K    +   +P
Sbjct: 784  TTLKEPAPTTPKKPAPKELAPTTTKG-PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 842

Query: 479  SPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQG 538
            +P TP +P   TS + TP    TT+  P     S  E TPE       K   +++P   G
Sbjct: 843  APTTPETPPPTTSEVSTP----TTTKEPTTIHKSPDESTPELSAEPTPKA-LENSPKEPG 897

Query: 539  LSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSST 598
            + +        P   + A  ++T      T  +T     +         K+      ++T
Sbjct: 898  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957

Query: 599  SEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPK 658
            ++V+ST+             +T FK+ +       T   +P    T+ TI  +  ++KP+
Sbjct: 958  TQVTSTTTQ----------DTTPFKITT-----LKTTTLAPKVTTTKKTITTTEIMNKPE 1002



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 165/855 (19%), Positives = 269/855 (31%), Gaps = 141/855 (16%)

Query: 473  SPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQS 532
            +P S PS      PS  +  +K+    T  S  P     +K  I  E I    S ++ Q 
Sbjct: 109  NPTSPPSSKKAPPPSGASQTIKS---TTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165

Query: 533  APALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNY 592
            + +    SS   ++       + AA++              + +  P+   P + ++ + 
Sbjct: 166  SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225

Query: 593  SPNS----STSEVSSTSASKAS----------IGQSPGLPSTTFKLPSNSLGFTATHNTS 638
              N     +T + S+T  +K S          I   P LP  +      SL  T    T+
Sbjct: 226  LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL--TVNKETT 283

Query: 639  PAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSS 698
                 T  T  Q+S   K K  S   + S+E                           +S
Sbjct: 284  VETKETTTTNKQTSTDGKEKTTSAKETQSIEK--------------------------TS 317

Query: 699  APSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIIS 758
            A   +  S     PT  +     G  +   +  TPT  +   +P S++            
Sbjct: 318  AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK---EPASTT------------ 362

Query: 759  PGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQ 818
            P   TP++ +S P    E  P    ++ +T +       +P          P     ++ 
Sbjct: 363  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-----EPAPTTTKEPAPTTPKEPAPTTT 417

Query: 819  EKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSH 878
            ++  P T+       ++     P P+      KKPA +  K    + TT  +P  ++   
Sbjct: 418  KEPAPTTTKSAPTTPKE-----PAPTT----PKKPAPTTPKEP--APTTPKEPTPTTPKE 466

Query: 879  RAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPS--KNDS 936
             A      +   P   A     +        P            P + + P+P+  K  S
Sbjct: 467  PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA-----------PTTPKEPAPTTTKEPS 515

Query: 937  FFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLA-APTG--HPPTSGV 993
              TP     + ++S       P      S    P     SP  T   APT    P  +  
Sbjct: 516  PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTP 573

Query: 994  EKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPS---KGTPSDGVSLSNLTQPSLT 1050
            +K   +T    +    K      ++KP+       AP+   +  P+    L+  T   L 
Sbjct: 574  KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 633

Query: 1051 ATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIR 1110
             T  ++       E   ++     P + EE   P  T    +A N      P    E   
Sbjct: 634  PTTPEKPAPTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPAPTTPKEPAP 690

Query: 1111 VPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKER 1170
               K                        +  P++  E A     G+   T  + AP   +
Sbjct: 691  TTPK------------------------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726

Query: 1171 APQFQESVGSFRSNSFNSTFEHHLPPSP--LEHGTPFQREPVGPSSAPPVPPKDHGGIFS 1228
             P  +E   +      ++T +   P +P      TP +  P  P    P  PK       
Sbjct: 727  KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG------ 780

Query: 1229 RDAPTHLPSVDLSNPFTKEAALAHAAPPP---PPGEHSGIPFPTPP---PPPPPGEHSSS 1282
              APT L     + P  K+ A    AP     P    S  P PT P    P  P E + +
Sbjct: 781  -TAPTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 837

Query: 1283 GGSGVPFSTPPPPPP 1297
                   +TP  PPP
Sbjct: 838  TPKKPAPTTPETPPP 852



 Score = 34.7 bits (78), Expect = 0.69
 Identities = 73/344 (21%), Positives = 108/344 (31%), Gaps = 63/344 (18%)

Query: 963  PDSPHPVPHRSLFSPQNTLAAPTGH----PPTSGVEKVLASTISTTSTIEFKNMLKNASR 1018
            PD+     ++   SP+ T A P       PP S   K  + T++  +T+E K       +
Sbjct: 236  PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 295

Query: 1019 KPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDST 1078
              +D K         +  +  S+   +   L  T +   +   + ET      L  P   
Sbjct: 296  TSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE- 349

Query: 1079 EEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSF 1138
                 P  T     AS       P  T++S     K                   + ++ 
Sbjct: 350  -----PTPTTPKEPASTTPKEPTPT-TIKSAPTTPK-----------------EPAPTTT 386

Query: 1139 DNGPSSASELASLGGGGSGGLTGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPP 1196
             + P++  E A          T  + AP   KE AP   +      + S  +T +   P 
Sbjct: 387  KSAPTTPKEPAPT--------TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438

Query: 1197 SPLEHG--TPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            +P +    TP +  P  P    P  PK+        APT            KE A    A
Sbjct: 439  TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT----------PKEPA--PTA 486

Query: 1255 PPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPP 1298
            P  P       P PT P  P P           P  T P  P P
Sbjct: 487  PKKPAPTTPKEPAPTTPKEPAPTTTKE------PSPTTPKEPAP 524



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 33/146 (22%), Positives = 46/146 (31%), Gaps = 20/146 (13%)

Query: 1168 KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVP--PKDHGG 1225
            KE AP  +E   +       +  +   P +P E      +EP   ++  P P  PK+   
Sbjct: 465  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524

Query: 1226 IFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGS 1285
              ++ APT         P       A   P  P    +  P PT P  P P         
Sbjct: 525  TTTKSAPT-----TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--------- 570

Query: 1286 GVPFSTPPPPPPPVDHSGVVPFPAPP 1311
                +TP  P P          P  P
Sbjct: 571  ----TTPKKPAPTTPKEPAPTTPKEP 592



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 6/124 (4%)

Query: 1195 PPSPLEHGTPFQREPVGPS-SAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHA 1253
            P +P E  +   +EP   +  + P  PK+     ++ APT     + +   TKE A    
Sbjct: 352  PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT--TPKEPAPTTTKEPAPTTP 409

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPP--PVDHSGVVP-FPAP 1310
              P P       P  T   P  P E + +       +TP  P P  P + +   P  PAP
Sbjct: 410  KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP 469

Query: 1311 PLAE 1314
               E
Sbjct: 470  TTKE 473



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 40/173 (23%), Positives = 55/173 (31%), Gaps = 22/173 (12%)

Query: 1160 TGFKTAPY--KERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHG--TPFQREPVGPSSA 1215
            T  K+AP   KE AP   +S  +       +T +   P +P E    TP +  P  P   
Sbjct: 525  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584

Query: 1216 PPVPPKDHGGIFSRD-----------------APTHLPSVDLSNPFTKEAALAHAAPPPP 1258
             P  PK+     ++                  APT    +  + P  K A      P P 
Sbjct: 585  APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPT 643

Query: 1259 PGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPP 1311
              E      P  P P  P E + +       +TP  P P          P  P
Sbjct: 644  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 138/669 (20%), Positives = 234/669 (34%), Gaps = 114/669 (17%)

Query: 391  KPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLAN 450
            +P   +  +T  PT      +   + TP P +  +T P P    T+++P+P         
Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP--------- 1349

Query: 451  VDLAKISSILSSLTSVMKNTGVSPASRPS-PGTPTSPSNLTSGLKTPAPATTTSHNPLAN 509
                   +   + T +   T V+P   P+   TPT+    T+   TP P  T +  P + 
Sbjct: 1350 ---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTS- 1405

Query: 510  ILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTT 569
                   TP +  + ++ T T +       + +  + T  P P        T    A TT
Sbjct: 1406 -------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPT--AITT 1456

Query: 570  VSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSL 629
             ST+     P+  Q     +   +P ++T+ V+ T             P+ T        
Sbjct: 1457 TSTVTPTPTPTGTQ-----TPTTTPITTTTTVTPT-------------PTPTGTQTPTPT 1498

Query: 630  GFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNI 689
              T T   +P   PT       +  S P   + + +P+            P  +G     
Sbjct: 1499 AITTTTTVTPTPTPTGT----QTPTSTPITTTTTVTPT------------PTPTGTQTPT 1542

Query: 690  PILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDT 749
            P   S  ++      P+  Q  PT+T I            +GT T   ++   T++   T
Sbjct: 1543 PTPISTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPT 1601

Query: 750  ---MSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDG 806
                S  S  ++P ++T + T +P P   ++ P  +  S +T       + +P   P+ G
Sbjct: 1602 PTPTSTKSTTVTPITTTTTVTATPTPTGTQT-PTMIPISTTT-------TVTPTPTPTTG 1653

Query: 807  MERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDT 866
               P +   ++                 +   S PPP +       P  S   SS L+++
Sbjct: 1654 STGPPTHTSTA--------------PIAELTTSNPPPES-----STPQTSRSTSSPLTES 1694

Query: 867  TEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGA---FSVRGNEP 923
            T    +LS+     +   + S  PPS      ++     LS  P    +      RG   
Sbjct: 1695 T---TLLSTLPPAIE---MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT 1748

Query: 924  GSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFS--PQNTL 981
            GS  +P+PS      T  +   S    T   LS P         P P   L      +T 
Sbjct: 1749 GSSSAPTPS------TVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTY 1802

Query: 982  AAPTGHPPTSGV--EKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGV 1039
             AP G    +G   +       S + T+EF N    ++  P+        PSK TP+   
Sbjct: 1803 YAP-GEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT------PTPSKSTPTPSK 1855

Query: 1040 SLSNLTQPS 1048
              S  ++P+
Sbjct: 1856 PSSTPSKPT 1864



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 102/488 (20%), Positives = 168/488 (34%), Gaps = 65/488 (13%)

Query: 318  ESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVE 377
            E+P P+P     + T               +PT  S +S TP P+T    V         
Sbjct: 1309 ENPTPTPITTTTTVT--------------PTPTPTSTQSTTPTPITTTTTVTPTPTP--- 1351

Query: 378  DDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSL 437
                       +         +T+V   PT   ++  + TP+  T T T P P P  T  
Sbjct: 1352 --------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQT 1402

Query: 438  SPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGT--PTSPSNLTSGLKT 495
              S  +              +   + T +   T V+P   P+ GT  PT  +  T+   T
Sbjct: 1403 PTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQAPTPTAITTTSTVT 1461

Query: 496  PAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASE 555
            P P  T +  P          TP +  + ++ T T +       +++  + T  P P + 
Sbjct: 1462 PTPTPTGTQTPTT--------TPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTP-TP 1512

Query: 556  AASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSP 615
              +Q+ +++P  TT +T+     P+  Q   P     +P S+T+ V+ T     +  Q+P
Sbjct: 1513 TGTQTPTSTPI-TTTTTVTPTPTPTGTQTPTP-----TPISTTTTVTPTPTPTGT--QTP 1564

Query: 616  GLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNF 675
                TT  + + +        T    P T +    ++    P   S  ++    +     
Sbjct: 1565 ----TTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTT 1620

Query: 676  LKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGP---TSTSIDNIDGTPVRDERSGT 732
            +   P  +G      I  S  ++      P+    GP   TST+      T      S T
Sbjct: 1621 VTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST 1680

Query: 733  PTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSS------------TRSPPPGRDESYPR 780
            P        P + S   +S L   I   S+ P S            T SPPP    S P 
Sbjct: 1681 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 1740

Query: 781  ELSNSVST 788
              +   +T
Sbjct: 1741 TPTRGTTT 1748



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 72/353 (20%), Positives = 123/353 (34%), Gaps = 39/353 (11%)

Query: 314  PDPEESPVPSPSMDAPSPTGSESPFQG---MGGEESQSPTMESEKSATPEPVTDNRDVED 370
            P P      S     P+PTG+++P           + +PT    ++ TP  +T    V  
Sbjct: 1449 PTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTP 1508

Query: 371  MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVP------VTMT 424
                                +    + ++T+    PT   +   + TP P      VT T
Sbjct: 1509 TPTPT-------------GTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555

Query: 425  ATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPT 484
             TP   +   T+   +     P          +++L + T+ M  T    +++ +  TP 
Sbjct: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615

Query: 485  SPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQ 544
            + +   +   TP    T +  P++   +       +  S    T T +AP       + +
Sbjct: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAP-------IAE 1668

Query: 545  SVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSST 604
              T NP P S     S S S   T  +T     L S+  P I  +    P++ T+  +++
Sbjct: 1669 LTTSNPPPESSTPQTSRSTSSPLTESTT-----LLSTLPPAIEMTSTAPPSTPTAPTTTS 1723

Query: 605  SASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKP 657
                 S       PSTT   P      T T ++S   P T  T   S+    P
Sbjct: 1724 GGHTLS-----PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTP 1771


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 124/597 (20%), Positives = 213/597 (35%), Gaps = 80/597 (13%)

Query: 415  SCTPVPVTMTATPPLPKPVNTSLSP-------------SPALALPNLANVDLAKI---SS 458
            S +P P+    +P + +P+ +S +P              P   +P+     + +    S 
Sbjct: 2121 SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSR 2180

Query: 459  ILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITP 518
            I  +LT++   T   P S  + G     S + +    P P  +    P AN+ S++   P
Sbjct: 2181 IALALTAISLGTARPPPSMSAAGLAARMSQVPA----PVPLMSLRTAPAANLASRI---P 2233

Query: 519  ESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASP-----ANTTVSTI 573
             +  +A++    ++ PA+    +L  S T     A   AS  T+ +P     A+    T 
Sbjct: 2234 AASAAAMNLASART-PAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTA 2292

Query: 574  KGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTA 633
               NL  +  P    + + + + +      T+A+  S  ++P  P++     +N +G  +
Sbjct: 2293 PAVNLAGARTPAALAALSLTGSGTPP----TAANYPSSSRTPQAPAS-----ANLVGPRS 2343

Query: 634  THNTSP---AAPPTEVTICQSSEVSK---PKLESES-TSPSLEMKIHNFLKGN---PGFS 683
             H T+P   A   T   +  +S  S    P L   + TSP + +  +  + G    P   
Sbjct: 2344 AHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLD 2403

Query: 684  GLNLNIPILSSLGSSAPSESHPSDFQR---GPTSTSIDNIDGTPVRDERSGTPTQDEMMD 740
                  P  +   S   SE  PS   R    P+ + +      P     S    Q   + 
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463

Query: 741  KPTSSSVDTMSLLSKIISPGSSTPSSTRS----PPPGRDESYPRELSNSVSTYRPFGLGS 796
              T+    + SL S  ++  +S+          P PG   S   E   S    +P  L +
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523

Query: 797  ESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKS 856
              P K+        SS   SS       +S        D E S  P    + L++ P+ +
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583

Query: 857  ILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAF 916
                  + +    +P                   P+ R    SS +    SSS       
Sbjct: 2584 PAPKEAVREGRPPEPT------------------PAKRKRRSSSSSSSSSSSS------- 2618

Query: 917  SVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRS 973
            S   +   S  S S S + S  +  S+ +S S +  G  +LP+   P  P P   RS
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 109/464 (23%), Positives = 178/464 (38%), Gaps = 57/464 (12%)

Query: 401  SVPTKPTENISK---ASSCTPVPVTMTATPPLPKPVNTSLSPSPALALP-NLANVDLAKI 456
            S+ T P  N++    A+S   + +    TP +P  VN + S +PA A   NLA+   A  
Sbjct: 2219 SLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVA 2278

Query: 457  SSILS------------SLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTP-APATTTS 503
             S ++            +L        ++  S    GTP + +N  S  +TP APA+   
Sbjct: 2279 PSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANL 2338

Query: 504  HNPL-ANILSKVEITPESILSAL---SKTQTQSAPALQGLS--------SLLQSVTGNPV 551
              P  A+  + V I      +AL   S T  + APAL G +        S  + V+G   
Sbjct: 2339 VGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTS 2398

Query: 552  PA--SEAASQSTSASPANTTVSTIKGRNL--------------PSSAQPFIPKSFNYSPN 595
            P     A S++  ++P+ + +++ +  +               P+  QP  P    +S +
Sbjct: 2399 PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFS-D 2457

Query: 596  SSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATH-----NTSPAAPPTEVTICQ 650
             S   ++ T+    S   S G  +TT     +  G  +       ++    PP      Q
Sbjct: 2458 QSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQ 2517

Query: 651  SSEVS--KPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDF 708
             S ++  +P  E  S+S S      +    +   S  +       S GSS P +   +  
Sbjct: 2518 PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA-L 2576

Query: 709  QRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTR 768
            +R P+ T         VR+ R   PT  +   + +SSS  + S  S   S  SS+ SS+ 
Sbjct: 2577 KRVPSPTPAPK---EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633

Query: 769  SPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSS 812
            S       S     S S +   P  L   +  K+P  G  R  S
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS 2677



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 136/617 (22%), Positives = 212/617 (34%), Gaps = 103/617 (16%)

Query: 403  PTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLAN---------VDL 453
            P+     ++   S  P PV + +    P     S  P+ + A  NLA+         V+L
Sbjct: 2197 PSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNL 2256

Query: 454  A--KISSILSSLTSVMKNTGVSPA--SRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLAN 509
            A  +  +  +++      T V+P+  +   P TPT+P+   +G +TPA         LA 
Sbjct: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPA--------ALAA 2308

Query: 510  ILSKVEITPESILSALSKTQTQSAPALQGL-------SSLLQSVTGNPVPASEAASQSTS 562
            +      TP +  +  S ++T  APA   L       ++   ++ G+   A+ A +  TS
Sbjct: 2309 LSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTS 2368

Query: 563  ASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPG---LPS 619
            A  A      + G NL S   P +P S     +  TS      A   +   +P    + S
Sbjct: 2369 ARMA----PALSGANLTS---PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS 2421

Query: 620  TTFKLPSNSLGFTATHNTSPAA-----PPTEVTICQSSEVSKPKLESESTSPSLEMKIHN 674
                 PS+ +G   + +  P A      P        S     +    + S SL      
Sbjct: 2422 ERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481

Query: 675  FLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDG----TPVRDERS 730
                + G     L++P        AP   H SD    P ST            P ++ RS
Sbjct: 2482 TTTSSAGDHNGMLSVP--------APGVPH-SDVGEPPASTGAQQPSALAALQPAKERRS 2532

Query: 731  GTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYR 790
             + +        +SSS  + S  S   S GSS+  S  S  P + E   + + +     +
Sbjct: 2533 SSSSSSS-----SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587

Query: 791  PFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLE 850
                    P   P+    R SS   SS                     S    S+  +  
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSS-------------------SSSSSSSSSSSS 2628

Query: 851  KKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPP-------SVRALLDSSENC 903
               + S   SS  S ++   P  +    +A         PP       S R  +DS  + 
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688

Query: 904  DRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLP---QK 960
              LS SP       V    P    SP PS  D      S+     +   G    P   ++
Sbjct: 2689 RSLSYSP-------VERRRP----SPQPSPRDQ--QSSSSERGSRRGQRGDSRSPSHKRR 2735

Query: 961  QYPDSPHPVPHRSLFSP 977
            +   SP P+ HRS  SP
Sbjct: 2736 RETPSPRPMRHRSSRSP 2752



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 161/714 (22%), Positives = 259/714 (36%), Gaps = 157/714 (21%)

Query: 322  PSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPE--------PVTDNRDVEDMEL 373
            P    D  SP   +S         S+SP+++S+   +P+        PVT+      +  
Sbjct: 1065 PDHRSDTSSPEVRQS--------HSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQ 1116

Query: 374  SDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENI----------SKASSCTPVPVTM 423
               E   S ++      + +   + S+S PT  + ++          SK     P     
Sbjct: 1117 DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176

Query: 424  TATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTP 483
            TA+PP  K      SP P    P              SSL  V K+T  +P  R   G  
Sbjct: 1177 TASPPRQKD---KFSPFPVQDRPE-------------SSL--VFKDTLRTPP-RERSGAG 1217

Query: 484  TSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLL 543
            +SP         P    T+S +             E ++  + K++  +   L  LSS L
Sbjct: 1218 SSPETKEQNSALP----TSSQD-------------EELMEVVEKSEEPAGQILSHLSSEL 1260

Query: 544  QSVTGNPVPASEAASQSTSAS---PANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSE 600
            + ++ +   +S    +  + S     + + ++++   +PS A  +    F          
Sbjct: 1261 KEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHF---------- 1310

Query: 601  VSSTSASKASIGQSPGLPSTTFKLPSNSLGFTAT-HNTSPAAPPTEVTICQSSEVSK--- 656
                S     +  SP        L  NS G      N+ P    TE+    SSEV +   
Sbjct: 1311 ----SPEHKELSNSP--------LRENSFGSPLEFRNSGPLG--TEMNTGFSSEVKEDLN 1356

Query: 657  -PKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTST 715
             P L    T PSL+MK  +    + G S   L+   +   G S+          +  +S 
Sbjct: 1357 GPFLNQLETDPSLDMKEQS--TRSSGHSSSELSPDAVEKAGMSS---------NQSISSP 1405

Query: 716  SIDNIDGTPVRDERSGTPTQDEMMDK-PTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGR 774
             +D +  TP R ERS + +  EM D  P + S  + S  S  +  GS TPS         
Sbjct: 1406 VLDAVPRTPSR-ERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSR-------- 1456

Query: 775  DESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYR 834
                     +S+S   P   G +   + PS G     S   S + K  P T         
Sbjct: 1457 ---------HSLSGSSP---GMKDIPRTPSRGRSECDS---SPEPKALPQTPRPR----- 1496

Query: 835  DFEYSGPPPSAMMN---LEKKPAKSILKSSKLSDTTEYQPI-LSSYSHRAQEFGVKSAFP 890
                S  P S  +N   L  +  +S  +SS    T    P+   S S  +QE  VK +  
Sbjct: 1497 ----SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552

Query: 891  PSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPD--SNHNSLS 948
            P  R+  DSS +    + +P    + S    E  S    SP ++ S  +P+      +  
Sbjct: 1553 PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP 1612

Query: 949  QSTTGHLSLPQKQYPDSPHPVPHRSLF---------SPQNTLAAPTG--HPPTS 991
            ++ +G  S P+ + P +P  +P RS           SP+ + +  +   HPP S
Sbjct: 1613 RAQSGSDSSPEPKAP-APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 150/733 (20%), Positives = 253/733 (34%), Gaps = 131/733 (17%)

Query: 310  KSTLPDPEE--SPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD 367
            KS  P  +   S  P P + + +P    S       E+S +P   S   ++P+P      
Sbjct: 826  KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP------ 879

Query: 368  VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVP-----TKPTENISKASSCTPVPVT 422
                              E +   P+  S   +S P     T P ++ S++SS  P P  
Sbjct: 880  ------------------ELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS--PQPKV 919

Query: 423  MTATPPLPKPVNTSLSPSPALALPNLA---NVDLAKISSILSSLTSVMKNTG-VSPASRP 478
                 P  +  + S SPSP+          +  ++  S++ S L     ++G  SP ++ 
Sbjct: 920  KAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV 979

Query: 479  SPGTP--------TSPSNLTSGLKTPAPATTTSHNPLANILSK---VEITPESI-LSALS 526
             P TP         SP         P P+ + S +P     SK   V+  P S+ L A  
Sbjct: 980  KPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGV 1039

Query: 527  KTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFI 586
            K+ T    +  G+SSL         P   + + S     +++   +++ ++  S      
Sbjct: 1040 KSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTS------ 1093

Query: 587  PKSFNYSPNSSTSEVSSTSASKASIGQ---SP----GLPSTTFKLPSNSLGFTATHNTSP 639
            PK      +S  +E++S S  +   G+   SP    G+     +  S+S  +    + S 
Sbjct: 1094 PKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSL 1153

Query: 640  AAPPTEVTICQSSEVSKPKLESESTSPSLEM-KIHNFLKGNPGFSGL----NLNIPILSS 694
                   T     +++ P  E  + SP  +  K   F   +   S L     L  P    
Sbjct: 1154 LGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER 1213

Query: 695  LGSSAPSESHPSDFQRGPTST------------------------------SIDNIDGTP 724
             G+ +  E+   +    PTS+                              S  N + +P
Sbjct: 1214 SGAGSSPETKEQN-SALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP 1272

Query: 725  VRDERSGTP-TQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESY--PRE 781
              +ER     T D+   + +  +V+  S+ S    P  S      S  P R+ S+  P E
Sbjct: 1273 EVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLE 1332

Query: 782  LSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGP 841
              NS         G  S  K+  +G                P  +  E +   D +    
Sbjct: 1333 FRNSGPLGTEMNTGFSSEVKEDLNG----------------PFLNQLETDPSLDMKEQST 1376

Query: 842  PPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVR-ALLDSS 900
              S   + E  P  ++ K+   S+ +   P+L +           SA  P ++  L  + 
Sbjct: 1377 RSSGHSSSELSP-DAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435

Query: 901  ENCDRLSSSPGLF------GAFSVRGNEPGSDRSP-SPSKNDSFFTPDSNHNSLSQSTTG 953
                R  SSPGL          S+ G+ PG    P +PS+  S         +L Q+   
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR- 1494

Query: 954  HLSLPQKQYPDSP 966
                P+ + P SP
Sbjct: 1495 ----PRSRSPSSP 1503



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 247/1225 (20%), Positives = 395/1225 (32%), Gaps = 193/1225 (15%)

Query: 315  DPEESPVPSPSMDAPSPTGSESPFQGMGGEESQS----PTMESEKSAT-PEPVTDNRDVE 369
            +P  +    PS    +     SP++    ++ +     P+   E+S+T PEP      + 
Sbjct: 312  EPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLA 371

Query: 370  DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPL 429
            +      +   +  + ++    P+E S      P K  E + ++SS         ++PP 
Sbjct: 372  ERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSE-------SSPPS 424

Query: 430  PKPVNTS--LSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPT--- 484
            P+P   S   S SP    P  A     +ISS   S TS  ++ G +   +    TP+   
Sbjct: 425  PQPTKVSRHASSSPESPKPAPAPGSHREISS---SPTSKNRSHGRAKRDKSHSHTPSRRM 481

Query: 485  ----SPSNLTSGLKTPAPATTTSHN---------------------PLANILSKVEITPE 519
                SP+    G       T   H+                     P     S+    P 
Sbjct: 482  GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPG 541

Query: 520  SILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLP 579
               S  ++ + +S  A +G S        +  PA+   S+S + +    + S    R   
Sbjct: 542  WSRSRNTQRRGRSRSARRGRSH-------SRSPATRGRSRSRTPARRGRSRSRTPARRRS 594

Query: 580  SSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFT-----AT 634
             S  P   +S + +P       S T A + S  +SP    +  + P+   G +     A 
Sbjct: 595  RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654

Query: 635  HNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFL--KGNPGFSGL------- 685
               S +  P      +S   ++    S S +P+   +  +    +G      L       
Sbjct: 655  RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714

Query: 686  NLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSS 745
            +         GSS+  ++     QR   S S   +  + +   RS +      +  P S 
Sbjct: 715  SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS------LSSPRSK 768

Query: 746  SVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRE-LSNSVSTYRPFGLGSESPYKQPS 804
            +   +SL  + +S  S  P      PP R  S   +  + S +  R     S  P KQ S
Sbjct: 769  AKSRLSL-RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS 827

Query: 805  DGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLS 864
                R S    S   K    T               PP    +   +   +S+    +  
Sbjct: 828  KTPSRQSHSSSSPHPKVKSGT---------------PPRQGSITSPQANEQSVTPQRRSC 872

Query: 865  DTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSS-SPGLFGAFSVRGNEP 923
              +   P L S +          + PP V++     ++  R SS  P +    S R    
Sbjct: 873  FESSPDPELKSRT--PSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH 930

Query: 924  GSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQ-----------KQYPDSPHPVPHR 972
                SPSPS+  S  TP  + +    S      LP+           K  P++P    H 
Sbjct: 931  SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHS 990

Query: 973  SLFSPQNTLAAPTGHPPT-SGVEKVLASTISTTSTIE-----FKNMLKNASRKPSDDKHF 1026
               SP   + A T   P+ SG +       S  S ++             S  P  + +F
Sbjct: 991  GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYF 1050

Query: 1027 GQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRI-ETRVSSSCLDLPDSTEEKGAPI 1085
                       GVS   L   S T+ D +       + ++   S  L     T  KG   
Sbjct: 1051 -----------GVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG--- 1096

Query: 1086 ETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSA 1145
                      R  S  P+  + S R P + +RG    AS +    +S   S F    S +
Sbjct: 1097 ---------GRSRSSSPVTELAS-RSPIRQDRGE-FSASPMLKSGMSPEQSRFQ---SDS 1142

Query: 1146 SELASLGGGGSGGLTGFKTAPYKER--APQFQESVGSFRSNSFNSTFEHHLPPSPLEHGT 1203
            S   ++      G +  +TA  KE+   P  +++  S              PP   +  +
Sbjct: 1143 SSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS--------------PPRQKDKFS 1188

Query: 1204 PFQREPVGPSSAPPVPPKDHGGIFSRD---APTHLPSVDLSNPFTKEAALAHAAPPPPPG 1260
            PF           PV  +    +  +D    P    S   S+P TKE   A     P   
Sbjct: 1189 PF-----------PVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA----LPTSS 1233

Query: 1261 EHSGIPFPTPPPPPPPGE---HSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGV 1317
            +   +         P G+   H SS    +  S      P V+    V            
Sbjct: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEMSTSN-FESSPEVEERPAVSLTLDQSQSQAS 1292

Query: 1318 AGAVAV-----------FPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVR 1366
              AV V           F  +H  L    L E+    P    + GP   ++N    S V+
Sbjct: 1293 LEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVK 1352

Query: 1367 ESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGI----ILRSPRPDFR 1422
            E L  P   L  L           S  SSG        D + ++G+     + SP  D  
Sbjct: 1353 EDLNGP--FLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV 1410

Query: 1423 PREPFLSRDPFHSLKRPRPPFARGP 1447
            PR P   R    S    +    R P
Sbjct: 1411 PRTPSRERSSSASSPEMKDGLPRTP 1435



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 84/362 (23%), Positives = 108/362 (29%), Gaps = 24/362 (6%)

Query: 1094 SNRRMSGEPIQTVESIRVPGKGNRGH-GREASRVGWFDLSTSGSSFDNGPSSASELASLG 1152
            S R+   +  +   S     K  R H    A      D S S S      +  + LA   
Sbjct: 236  SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRS 295

Query: 1153 GGGSGGLTGFKTAPYKE------RAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQ 1206
               + G  G   AP+ E      + P   E+     S+ +    +     S        +
Sbjct: 296  PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPE 355

Query: 1207 REPVGPSSAPPVP--PKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSG 1264
            R   GP    P P   + HGG     A T L S +  NP ++ +     +PP  P +   
Sbjct: 356  RSSTGPEPPAPTPLLAERHGGSPQPLATTPL-SQEPVNPPSEASPTRDRSPPKSPEKLPQ 414

Query: 1265 IPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVF 1324
                   PP P     S   S  P S P P P P  H  +   P      HG A      
Sbjct: 415  SSSSESSPPSPQPTKVSRHASSSPES-PKPAPAPGSHREISSSPTSKNRSHGRAKR---- 469

Query: 1325 PKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHG 1384
             K HS      +       P     G    R     G SR R      S S +  G    
Sbjct: 470  DKSHSHTPSRRMGRSRS--PATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527

Query: 1385 GGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFA 1444
                G S S   P  G S      R G    + R     R P           R R P  
Sbjct: 528  PQRRGRSRSPQRP--GWSRSRNTQRRGRSRSARRGRSHSRSP-----ATRGRSRSRTPAR 580

Query: 1445 RG 1446
            RG
Sbjct: 581  RG 582



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 80/390 (20%), Positives = 136/390 (34%), Gaps = 50/390 (12%)

Query: 286  KVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEE 345
            +V  +AY+  + R +     LD+ +S  P    S     S  APSP+        MG   
Sbjct: 2384 RVPLSAYERVSGRTS--PPLLDRARSRTPPSAPSQSRMTSERAPSPSSR------MGQAP 2435

Query: 346  SQS---PTMESEKSATPEPVTDNRD---VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVS 399
            SQS   P  +  +S  P   +D       +   ++  +   S  +             +S
Sbjct: 2436 SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS 2495

Query: 400  TSVPTKPTENISK--ASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKIS 457
               P  P  ++ +  AS+    P  + A  P  +  ++S S S + +            S
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS------------S 2543

Query: 458  SILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEIT 517
            S  SS +S   ++G S +       P  P      + +P PA   +           E T
Sbjct: 2544 SSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA----VREGRPPEPT 2599

Query: 518  PESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRN 577
            P       S + + S+ +    SS   S + +   +S ++S S+S+S ++ + +    + 
Sbjct: 2600 PAK-RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658

Query: 578  LPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNT 637
            LP  A P  P        S    + S   S+ S+  SP                      
Sbjct: 2659 LPKPASPKKPPPGERRSRSPRKPIDSLRDSR-SLSYSP----------------VERRRP 2701

Query: 638  SPAAPPTEVTICQSSEVSKPKLESESTSPS 667
            SP   P +     S   S+     +S SPS
Sbjct: 2702 SPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 176/861 (20%), Positives = 300/861 (34%), Gaps = 161/861 (18%)

Query: 388  RKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTM----TATPPLPKPVNTSLSP--SP 441
            R+   +  S VS       T  +++  S +  P T     + TPP+ +  + S +P  + 
Sbjct: 1908 RRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTR 1967

Query: 442  ALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATT 501
              +    + +   +  S  S +T     +  SP +R    + TSP           PA  
Sbjct: 1968 RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIR 2027

Query: 502  TSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQST 561
                    +L +      S L+   ++++++    +G  SL +S      PA    S S 
Sbjct: 2028 RRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRS-----PPAIRRRSASG 2082

Query: 562  SASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVS------------------S 603
            S+S  + + +    RN   S  P  P + N S  S  S  S                   
Sbjct: 2083 SSSDRSRSATPPATRNHSGSRTP--PVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLG 2140

Query: 604  TSASKASI----------GQSPGLPS-TTFKLPSN------SLGFTATHNTSPAAPPTEV 646
            +S +  S+          G  P +P      +P N      +L  TA  +   A PP  +
Sbjct: 2141 SSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAI-SLGTARPPPSM 2199

Query: 647  T----ICQSSEVSKP-KLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPS 701
            +      + S+V  P  L S  T+P+      N     P  S   +N  + S+   + P+
Sbjct: 2200 SAAGLAARMSQVPAPVPLMSLRTAPAA-----NLASRIPAASAAAMN--LASARTPAIPT 2252

Query: 702  ESHPSDFQRGPTSTSIDNI---------DGTPVRDERSGTPTQDEMMDKPTSSSVDTMSL 752
              + +D  R P + +  N+             + D R+ T     +    T +++  +SL
Sbjct: 2253 AVNLAD-SRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSL 2311

Query: 753  LSKIISP-GSSTPSSTRSP--PPGRDESYPREL----------SNSVSTYRPFGLGS--- 796
                  P  ++ PSS+R+P  P   +   PR            S + +   P  L S   
Sbjct: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM 2371

Query: 797  ---------ESPYKQPSDGMERPSS-----LMDSSQEKFYPDTSFQEDEDYRDFEYSGPP 842
                      SP + P    ER S      L+D ++ +  P    Q     R      P 
Sbjct: 2372 APALSGANLTSP-RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS----RMTSERAPS 2426

Query: 843  PSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQ--------EFGVKSAFPPSVR 894
            PS+ M   + P++S+L  ++        P+ S++S +++          G +S    +V 
Sbjct: 2427 PSSRMG--QAPSQSLLPPAQ---DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481

Query: 895  ALLDSSENCDRLSSSPGLFGAFSVRGNEPGSD-----------------RSPSPSKNDSF 937
                S+ + + + S P      S  G  P S                  RS S S + S 
Sbjct: 2482 TTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541

Query: 938  FTPDSNHNSLSQSTTGHLS----------LPQKQYPDSPHPVPHRSLFSPQNTLAAPTGH 987
             +  S+ +S S S++G  S           P+      P P P     +P+   A   G 
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP-----APKE--AVREGR 2594

Query: 988  PPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQP 1047
            PP     K    + S++S+    +   ++S   S       + S  + S   S  +  +P
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654

Query: 1048 SLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPI---- 1103
               A  +    +      R S S     DS  +      +L Y     RR S +P     
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS----RSLSYSPVERRRPSPQPSPRDQ 2710

Query: 1104 QTVESIRVPGKGNRGHGREAS 1124
            Q+  S R   +G RG  R  S
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPS 2731



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 207/1020 (20%), Positives = 336/1020 (32%), Gaps = 169/1020 (16%)

Query: 200  YKRSEDQIELKEKQLSTMRVDVCSTET-----LKCLKDKTGGKKFSKEFEEASSKLEEF- 253
            YK  E+   L+   +     D+   E      L+CL+ +   ++   E ++   K+  F 
Sbjct: 36   YKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFR 95

Query: 254  VNGLDKQVKNG---------PSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVN-NLK 303
            +  L+K V  G         P++TE  + A +  E + + ++       ++ +  + + +
Sbjct: 96   LMLLEKDVNPGGKEETPGQRPAVTETHQLAEL-NEKKNERLRAAFGISDSYVDGSSFDPQ 154

Query: 304  KKLDQLKSTLPDPEESPVP------SPSMDAPSPTGSESPFQGMGGE--ESQSPTMESEK 355
            ++  + K   P+P   P P      S S  +P+P   +   +   G   ES SP  E +K
Sbjct: 155  RRAREAKQPAPEP---PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK 211

Query: 356  SATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPT-----KPTENI 410
            S+  +      + +  +         +      K+K  ++S  +T  P      + T   
Sbjct: 212  SSKKKKHRSESESKKRKHRSPTPKSKR----KSKDKKRKRSRSTTPAPKSRRAHRSTSAD 267

Query: 411  SKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNT 470
            S +SS T    + +A            SPSPA       +   ++  +  +   S  +  
Sbjct: 268  SASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETA 327

Query: 471  GVSPAS---------------RPSPGTPTSPSNLTSGLKTPAPATTT------SHNPLAN 509
               P+S               RPSP    SP   ++G + PAP          S  PLA 
Sbjct: 328  TKQPSSPYEDKDKDKKEKSATRPSP----SPERSSTGPEPPAPTPLLAERHGGSPQPLAT 383

Query: 510  I-LSKVEITPESILSALSKTQTQSAP-ALQGLSSLLQSVTGNPVPASEAASQSTSASPAN 567
              LS+  + P    S  S T+ +S P + + L     S +  P P     S+  S+SP +
Sbjct: 384  TPLSQEPVNPP---SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440

Query: 568  TTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSN 627
               +   G +   S+    P S N S   +  + S +      +G+S   P+T  +  S 
Sbjct: 441  PKPAPAPGSHREISSS---PTSKNRSHGRAKRDKSHSHTPSRRMGRSRS-PATAKRGRSR 496

Query: 628  SLGFTATHNTSPAAPP--TEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGL 685
            S   T   ++   +P      +  +      P+    S SP             PG+S  
Sbjct: 497  SRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ-----------RPGWS-R 544

Query: 686  NLNIPILSSLGSSAPSESHPSD--------------------------FQRGPTSTSIDN 719
            + N        S+    SH                               R  T T   +
Sbjct: 545  SRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRS 604

Query: 720  IDGTPVR--DERSGTP------TQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPP 771
               TP R    RS TP      T+  +  +  S S    S  S+  +P     S +R+P 
Sbjct: 605  RSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA 664

Query: 772  -PGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQED 830
              GR  S      +  S  R       S  + P  G  R  SL+   +            
Sbjct: 665  RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGR------------ 712

Query: 831  EDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFP 890
               R  +  G   S+     K         S  S   +   I S  S        K+   
Sbjct: 713  SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 891  PSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQS 950
             S+R  L  S  C +  S      + S         R+P P ++ S  +P     S + S
Sbjct: 773  LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP-PRRSRSSSSPPPKQKSKTPS 831

Query: 951  TTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFK 1010
               H S        SPHP         Q ++ +P  +     V     S   ++   E K
Sbjct: 832  RQSHSS-------SSPHPKVKSGTPPRQGSITSPQAN--EQSVTPQRRSCFESSPDPELK 882

Query: 1011 NMLKNASRKPSDDKHFGQAP----SKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETR 1066
                  SR PS     G +P    S   P    S S+  QP + A    +Q  H      
Sbjct: 883  ------SRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH------ 930

Query: 1067 VSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRV 1126
             S S    P     +  P           R  S  P   VES  +P   + G     ++V
Sbjct: 931  -SGSSSPSPSRVTSRTTP----------RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV 979



 Score = 38.5 bits (88), Expect = 0.048
 Identities = 91/409 (22%), Positives = 132/409 (32%), Gaps = 71/409 (17%)

Query: 909  SPGLFGAFSVRG--------NEPGSDRSPSPSKNDSFFTPDSNH-----NSLSQSTTGHL 955
            +P    A S+ G        N P S R+P    + +   P S H     N     T   L
Sbjct: 2302 TPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAAL 2361

Query: 956  SLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEK--VLASTISTTSTIEFKNML 1013
            +            +   +L SP+  L+A   +   SG     +L    S T         
Sbjct: 2362 APASLTSARMAPALSGANLTSPRVPLSA---YERVSGRTSPPLLDRARSRTPPSAPSQSR 2418

Query: 1014 KNASRKPSDDKHFGQAPSKG------------TPSDGVSLSNLTQPSLTATDQQQQEEHY 1061
              + R PS     GQAPS+              PS     S       T     Q     
Sbjct: 2419 MTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSG 2478

Query: 1062 RIETRVSSS-----CLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGN 1116
             + T  SS+      L +P      G P   +G   AS        +  ++    P K  
Sbjct: 2479 AVATTTSSAGDHNGMLSVP----APGVPHSDVGEPPASTGAQQPSALAALQ----PAKER 2530

Query: 1117 RGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSG----GLTGFKTAPYKERAP 1172
            R     +S       S+S SS  +  SS+S  +S    GS          K  P    AP
Sbjct: 2531 RSSSSSSSSSS----SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586

Query: 1173 QFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAP 1232
            +  E+V   R            PP P    TP +R+    SS+            S  + 
Sbjct: 2587 K--EAVREGR------------PPEP----TPAKRKRRSSSSSSSSSSSSSSS--SSSSS 2626

Query: 1233 THLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSS 1281
            +   S   S+  +  ++ + ++P P       +P P  P  PPPGE  S
Sbjct: 2627 SSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675



 Score = 30.8 bits (68), Expect = 10.0
 Identities = 36/168 (21%), Positives = 59/168 (35%), Gaps = 15/168 (8%)

Query: 314  PDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMEL 373
            P  +     SP   AP+P       +     + + P+ E   S    P       E    
Sbjct: 1612 PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSP-------EHPPK 1664

Query: 374  SDVEDDGSKIIVEDRKEK---PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
            S     GS+   E + +    P  +S+ S+   T+      ++ S +  P T + TPP  
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724

Query: 431  KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRP 478
            +   +  SP PA       +    +  S  S  T      G SP+ +P
Sbjct: 1725 RRSPSVSSPEPA-----EKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 243/1228 (19%), Positives = 404/1228 (32%), Gaps = 288/1228 (23%)

Query: 227  LKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVK 286
            + C K  TG    +++ ++    LE+ ++ LDK   +    T +  N+G    +Q K+  
Sbjct: 166  INCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSG---NSQTKQKS 222

Query: 287  VVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEES 346
                   +F  ++    K   +   T   PEES                         E 
Sbjct: 223  T------SFPEKITAASKTTYKTTGT---PEESEKT----------------------ED 251

Query: 347  QSPTMESEKSATPEPVTDNRDVEDMELS----DVEDDGSKIIVEDRKEKPAEKSAV---- 398
               T+ S+K  T         +   EL+    +  + G +   E+    PAE +      
Sbjct: 252  SRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERT 311

Query: 399  ----STSVPTKPTENISKASS--CTPVPVTMTATPPLPKPVNTSLSPS-PALALPNLANV 451
                +T  P +P EN  + ++    P P   T    +    NT+L P+ P       AN 
Sbjct: 312  ANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTAN- 370

Query: 452  DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANIL 511
                            +NT  SPA     G  T+  N T     P+PA  T H       
Sbjct: 371  ----------------ENTTPSPAEPTEHGERTANENTT-----PSPAEPTEHG------ 403

Query: 512  SKVEITPESILSALSKTQTQSAPALQ-GLSSLLQSVTGNPVPAS------EAASQSTSAS 564
               E TP     A  KT + SA + + G  + L +    P PA         A+++T+ S
Sbjct: 404  ---ERTP----FANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPS 456

Query: 565  PANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKL 624
            PA  T +     N  ++  P  P     + N  T+    T+ S A   ++          
Sbjct: 457  PAGPTENRETTANEKTTLSPVEP-----TENRETTANEKTTPSPAEPTEN---------- 501

Query: 625  PSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSG 684
                  F     TS +A PTE          +  L +E+T+PS      N  +       
Sbjct: 502  -GQRTPFANEKTTSSSAEPTE-------HGERTPLANENTTPSPAEPTENRER------- 546

Query: 685  LNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTS 744
                    ++   + PS + P++           N D TP+ +E++ TP+  E    PT 
Sbjct: 547  --------TANEKTTPSPAEPTE-----------NGDRTPLANEKT-TPSLAE----PTE 582

Query: 745  SSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPS 804
            +   T     K         +S+ + P   +E  P  L+N  +T  P          +P+
Sbjct: 583  NGQRTPFANEKT--------TSSSAEPTEHEERTP--LANENTTPSP---------AEPT 623

Query: 805  DGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLS 864
            +  ER      ++ E   P  +             GP  +  M   +K      + ++  
Sbjct: 624  ENRER------TANENTTPSPA-------------GPTENREMTANEKTTLFPAEPTENR 664

Query: 865  DTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPG 924
            + T  +   SS +   +  G ++ F         ++E     S+ P   G  +   NE  
Sbjct: 665  ERTANEKTTSSPAEPTEN-GQRTPF---------ANEKTTSSSAEPTEHGERTPLANENT 714

Query: 925  SDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAP 984
            +     P++N           + ++ TT          P    P  +R   + +NT  +P
Sbjct: 715  TLSPAEPTEN--------RERTANEKTT----------PFPAEPTENRERTANENTTPSP 756

Query: 985  TGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNL 1044
               P  +G    LA+  +T S  E     +N  R P  ++      S   P++    + L
Sbjct: 757  A-QPTENGDRTPLANEKTTPSLAE---PTENGKRTPFANEK--TTSSSAEPTEHAERTPL 810

Query: 1045 TQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGA----------PIETLGYHSAS 1094
               + T++  +  E   R     ++     P    E  A          P E   + +  
Sbjct: 811  ANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANE 870

Query: 1095 NRRMS-GEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGG 1153
            N  +S  EP +  E   +  +       E +  G        + F N  ++ S       
Sbjct: 871  NTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENG------ERTPFTNEKTTPSSAEPTEH 924

Query: 1154 GGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPS 1213
            G    L    T P +    +  E + + ++           P  P EHG     E   PS
Sbjct: 925  GERTPLANEITTPSRAEPTEHGERIANEKATPS--------PAKPTEHGETTVNEDTTPS 976

Query: 1214 SAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPP 1273
            SA P    +                    P   E            GE +     TP P 
Sbjct: 977  SAEPTENGER------------------TPLANENTTTSPTESTEHGERTANEKTTPSPA 1018

Query: 1274 PPP--GEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKDHSSL 1331
             P   GE + S        T P P  P +H  + P      + +       V P +H   
Sbjct: 1019 EPTEHGERTPSANE----KTIPSPAKPTEHEEMTP------SANENTTPSPVKPTEHGE- 1067

Query: 1332 LQGTLA-EHFGVLP-GPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGGGG 1389
             + TLA E   + P GP +HG  T          ++  SL  P+   E    P+      
Sbjct: 1068 -KTTLANEKITLSPEGPTEHGAKTT-----SANEKITPSLAKPTEHGERTTSPN------ 1115

Query: 1390 GSNSSSGPPLGPSHRDTISRSGIILRSP 1417
                +S       HRD  + + +I  +P
Sbjct: 1116 -DKITSSAAESTEHRDRATSANVITPAP 1142


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 131/564 (23%), Positives = 206/564 (36%), Gaps = 81/564 (14%)

Query: 314 PDPEESPVP----SPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVE 369
           PD   SP+     S   ++PS   + S        E+   + +  K     P+  N+   
Sbjct: 41  PDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPLKSNKRQR 97

Query: 370 DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPL 429
           +   SD E+        DR      K+    S P  P+E   ++S    V    ++ P  
Sbjct: 98  EKVASDTEE-------ADRTSSKKTKTQ-EISRPNSPSEGEGESSDSRSVNDEGSSDPKD 149

Query: 430 PKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKN-TGVSPA-SRPSPGTPTSPS 487
               N S SPS      N ++ D +    +L +    ++  TGV+PA S   PGTP  P 
Sbjct: 150 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP- 208

Query: 488 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT 547
             T G    A A     +P A   S+    P++  + +  T  Q APAL           
Sbjct: 209 --TPGPTPSATAVPPQGSPTA---SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 263

Query: 548 GNPVP------ASEAASQSTSASPANTTVSTIKGRNLPSSAQ-------PFIPKSFNYSP 594
            +P P       + +A Q ++ S A   +   +G   P S Q       P  P+ F   P
Sbjct: 264 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-QGPPGPHSLQAGPLLQHPGPPQPFGLPP 322

Query: 595 NSSTSEVSSTSASKASIGQSPGL--PSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSS 652
            +S  +        A +G SP    P T+ +LP++     +        PP E  +   +
Sbjct: 323 QASQGQ--------APLGTSPAAAYPHTSLQLPASQSALQSQQ------PPREQPL-PPA 367

Query: 653 EVSKPKLESESTSPSLEMKIHNFLKGNPGFSG-----LNLNIPI------LSSLGSSAPS 701
            ++ P ++   T+P  ++      K  P  SG     +N N+P       LSSL +  P 
Sbjct: 368 PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 427

Query: 702 ESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGS 761
            +HP   Q  P S  + +    P         TQ + +  P +S   T         P +
Sbjct: 428 SAHPPPLQLMPQSQPLPSSPAQP------PGLTQSQNLPPPPASHPPTGLHQVAPQPPFA 481

Query: 762 STPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKF 821
             P     PPP    + P     S ST  P G G+ +  + P  G       +       
Sbjct: 482 QHPFVPGGPPPITPPTCP-----STST-PPAGPGTSA--QPPCSGAAASGGSIAGGSSCP 533

Query: 822 YPDTSFQED--EDYRDFEYSGPPP 843
            P    +E+  +D  + E   PPP
Sbjct: 534 LPTVQIKEEALDDAEEPESPPPPP 557



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 60/312 (19%)

Query: 1196 PSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTH--LPSVDLSNPFTKEAALAHA 1253
            PS    GTP    P    SA  VPP+  G   +  AP     P+  + +   ++A   H 
Sbjct: 197  PSSAPPGTPQLPTPGPTPSATAVPPQ--GSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 254

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPP-----PPPPPVDHSGVV--- 1305
              PP P      P P+P PP  P   S+   S    + PP     PP P    +G +   
Sbjct: 255  QRPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 311

Query: 1306 -----PFPAPPLAEHGVA----GAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRD 1356
                 PF  PP A  G A       A +P  H+SL              PR+   P    
Sbjct: 312  PGPPQPFGLPPQASQGQAPLGTSPAAAYP--HTSLQLPASQSALQSQQPPREQPLPPAP- 368

Query: 1357 LNGPGLSRVRESLTLPSHSLE----HLGPPHGGGGGGGSNSSSGPP---------LGPSH 1403
                 +  ++   T P   L     H  PPH  G    S +++ PP         L   H
Sbjct: 369  ---LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 425

Query: 1404 RDTISRSGIILR---SPRPDFRPREPFLSRDP-------------FHSLKRPRPPFARGP 1447
              +     + L     P P    + P L++                H +  P+PPFA+ P
Sbjct: 426  PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVA-PQPPFAQHP 484

Query: 1448 PFFAPKRPFFPP 1459
                   P  PP
Sbjct: 485  FVPGGPPPITPP 496



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 111/532 (20%), Positives = 161/532 (30%), Gaps = 99/532 (18%)

Query: 830  DEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAF 889
            +ED R    + P  ++  + + K A+++ KS+K        P+ S+   R +        
Sbjct: 49   NEDIRSSGRNSPSAASTSSNDSK-AETVKKSAKKVKEEASSPLKSNKRQREK-------- 99

Query: 890  PPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGS---DRSPSPSKNDSFFTPDSNHNS 946
                  +   +E  DR SS        S R N P     + S S S ND   +   + + 
Sbjct: 100  ------VASDTEEADRTSSKKTKTQEIS-RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ 152

Query: 947  LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTS-----GVEKVLASTI 1001
             ++ST+  +  PQ    DS      + L +    L APTG  P       G  ++     
Sbjct: 153  DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 212

Query: 1002 STTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHY 1061
            + ++T         AS+ P+      QAP+   P   +  +    P      Q+    H 
Sbjct: 213  TPSATAVPPQGSPTASQAPNQP----QAPTAPVPHTHIQQAPALHP------QRPPSPHP 262

Query: 1062 RIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGR 1121
                        L  S  +  AP      H+       G P                   
Sbjct: 263  PPHPSPHPPLQPLTGSAGQPSAPS-----HAQPPLHGQGPP------------------- 298

Query: 1122 EASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSF 1181
                 G   L         GP     L      G   L     A Y   + Q   S  + 
Sbjct: 299  -----GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 353

Query: 1182 RSNSFNSTFEHHLPPSPLE--HGTPFQREPVGPSSAPPV---PPKDHG-GIFSRDAPTHL 1235
            +S       E  LPP+PL   H  P    P+    AP     PP   G   FS +A    
Sbjct: 354  QSQQ--PPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 411

Query: 1236 PSV--DLSNPFTKEAALAHAAP--------------------------PPPPGEHSGIPF 1267
            P     LS+  T     AH  P                          PPPP  H     
Sbjct: 412  PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGL 471

Query: 1268 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAG 1319
                P PP  +H    G   P + P  P      +G      PP +    +G
Sbjct: 472  HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523



 Score = 37.7 bits (86), Expect = 0.082
 Identities = 111/536 (20%), Positives = 178/536 (33%), Gaps = 98/536 (18%)

Query: 460 LSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPE 519
           +S+L S  K    SP  R SP    +    +SG  +P+ A+T+S++  A          E
Sbjct: 27  MSTLRSGRKKQPASPDGRTSP---INEDIRSSGRNSPSAASTSSNDSKA----------E 73

Query: 520 SILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLP 579
           ++  +  K + +++  L+      + V  +   A   +S+ T     +   S  +G    
Sbjct: 74  TVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGES 133

Query: 580 SSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPS-TTFKLPSNSLGFTATHNTS 638
           S +     +S N   +S   ++   + S      SP +PS    +  S+S          
Sbjct: 134 SDS-----RSVNDEGSSDPKDIDQDNRS-----TSPSIPSPQDNESDSDSSAQQQMLQAQ 183

Query: 639 PAA--PPTEVTICQSS-EVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSL 695
           P A   PT VT   SS     P+L +   +PS                     +P     
Sbjct: 184 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATA------------------VP----- 220

Query: 696 GSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSK 755
              +P+ S   +  + PT+     +  T ++   +  P +      P   S         
Sbjct: 221 PQGSPTASQAPNQPQAPTAP----VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT 276

Query: 756 IISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMD 815
             +   S PS  + P  G+    P  L        P   G   P+  P    +  + L  
Sbjct: 277 GSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP---GPPQPFGLPPQASQGQAPL-G 332

Query: 816 SSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSS 875
           +S    YP TS Q        +   PP    +     PA   +   K   TT    + + 
Sbjct: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAP 388

Query: 876 YSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKND 935
            +H+          PP +              S P     FS+  N P     P P+   
Sbjct: 389 QAHK---------HPPHL--------------SGP---SPFSMNANLP-----PPPALKP 417

Query: 936 SFFTPDSNHNSLSQSTTGHLSLPQKQ-YPDSPHPVPHRSLFSPQNTLAAPTGHPPT 990
              +  S H+  S        +PQ Q  P SP   P   L   QN    P  HPPT
Sbjct: 418 --LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPPT 469



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 118/595 (19%), Positives = 187/595 (31%), Gaps = 108/595 (18%)

Query: 741  KPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPY 800
            +P S    T  +   I S G ++PS+  +          ++ +  V       L S    
Sbjct: 37   QPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQ 96

Query: 801  KQP----SDGMERPSSLMDSSQEKFYPDTSFQ---EDEDYRDFEYSGPPPSAMMNLEKKP 853
            ++     ++  +R SS    +QE   P++  +   E  D R     G      ++ + + 
Sbjct: 97   REKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRS 156

Query: 854  AKSILKSSKL----SDTTEYQPILSSYSHRAQE-FGVK---SAFPPSVRALLDSSENCDR 905
                + S +     SD++  Q +L +     Q   GV    S+ PP    L         
Sbjct: 157  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA 216

Query: 906  LSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDS 965
             +  P      S   N+P +  +P P            H  + Q+   H   PQ+  P S
Sbjct: 217  TAVPPQGSPTASQAPNQPQAPTAPVP------------HTHIQQAPALH---PQR--PPS 259

Query: 966  PHPVPHRSLFSPQNTLAAPTGHP--PTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDD 1023
            PHP PH S   P   L    G P  P+     +         +++   +L++    P   
Sbjct: 260  PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH----PGPP 315

Query: 1024 KHFGQAP--SKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEK 1081
            + FG  P  S+G    G             T       H  ++   S S L       E+
Sbjct: 316  QPFGLPPQASQGQAPLG-------------TSPAAAYPHTSLQLPASQSALQSQQPPREQ 362

Query: 1082 GAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNG 1141
              P   L            +P  T    ++P      H    S    F ++ +       
Sbjct: 363  PLPPAPLAMPHI-------KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP---- 411

Query: 1142 PSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEH 1201
            P +   L+SL    S         P  +  PQ Q  + S  +     T   +LPP P  H
Sbjct: 412  PPALKPLSSL----STHHPPSAHPPPLQLMPQSQP-LPSSPAQPPGLTQSQNLPPPPASH 466

Query: 1202 GT----------PFQREPVGPSSAPPVPPKD------------------------HGGIF 1227
                        PF + P  P   PP+ P                           GG  
Sbjct: 467  PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI 526

Query: 1228 SRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSS 1282
            +  +   LP+V +      +A    + PPPP       P P P     P   S S
Sbjct: 527  AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS-----PSPEPTVVDTPSHASQS 576



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 45/163 (27%), Positives = 53/163 (32%), Gaps = 51/163 (31%)

Query: 1188 STFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKE 1247
            S+   H PPS   H  P Q  P   S   P  P    G+       +LP    S+P T  
Sbjct: 419  SSLSTHHPPSA--HPPPLQLMP--QSQPLPSSPAQPPGLTQSQ---NLPPPPASHPPT-- 469

Query: 1248 AALAHAAPPPPPGEHSGIPFPTPP-----------PPPPPGEH-------------SSSG 1283
              L   AP PP  +H  +P   PP           PP  PG               S +G
Sbjct: 470  -GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAG 528

Query: 1284 GSGVPFST-----------------PPPPPPPVDHSGVVPFPA 1309
            GS  P  T                 PPPP  P     VV  P+
Sbjct: 529  GSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 571



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 52/178 (29%), Positives = 62/178 (34%), Gaps = 43/178 (24%)

Query: 1182 RSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLS 1241
            R   FN T  HH       H    Q++P+   SA PV P                   L 
Sbjct: 862  RLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP-------------------LV 902

Query: 1242 NPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDH 1301
            +P T    LA    P PPG       P P    PP EH         F TP P   P   
Sbjct: 903  DPLTAGPHLARF--PYPPG-----TLPNPLLGQPPHEHEML--RHPVFGTPYPRDLP--- 950

Query: 1302 SGVVPFPAPPL-AEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGG--PTQRD 1356
             G +P   PP+ A H +    A      S+ LQ    E   +   P  HGG  P+Q D
Sbjct: 951  -GAIP---PPMSAAHQLQAMHA-----QSAELQRLAMEQQWLHGHPHMHGGHLPSQED 999


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 131/564 (23%), Positives = 206/564 (36%), Gaps = 81/564 (14%)

Query: 314  PDPEESPVP----SPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVE 369
            PD   SP+     S   ++PS   + S        E+   + +  K     P+  N+   
Sbjct: 595  PDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPLKSNKRQR 651

Query: 370  DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPL 429
            +   SD E+        DR      K+    S P  P+E   ++S    V    ++ P  
Sbjct: 652  EKVASDTEE-------ADRTSSKKTKTQ-EISRPNSPSEGEGESSDSRSVNDEGSSDPKD 703

Query: 430  PKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKN-TGVSPA-SRPSPGTPTSPS 487
                N S SPS      N ++ D +    +L +    ++  TGV+PA S   PGTP  P 
Sbjct: 704  IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP- 762

Query: 488  NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT 547
              T G    A A     +P A   S+    P++  + +  T  Q APAL           
Sbjct: 763  --TPGPTPSATAVPPQGSPTA---SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817

Query: 548  GNPVP------ASEAASQSTSASPANTTVSTIKGRNLPSSAQ-------PFIPKSFNYSP 594
             +P P       + +A Q ++ S A   +   +G   P S Q       P  P+ F   P
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-QGPPGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 595  NSSTSEVSSTSASKASIGQSPGL--PSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSS 652
             +S  +        A +G SP    P T+ +LP++     +        PP E  +   +
Sbjct: 877  QASQGQ--------APLGTSPAAAYPHTSLQLPASQSALQSQQ------PPREQPL-PPA 921

Query: 653  EVSKPKLESESTSPSLEMKIHNFLKGNPGFSG-----LNLNIPI------LSSLGSSAPS 701
             ++ P ++   T+P  ++      K  P  SG     +N N+P       LSSL +  P 
Sbjct: 922  PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 981

Query: 702  ESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGS 761
             +HP   Q  P S  + +    P         TQ + +  P +S   T         P +
Sbjct: 982  SAHPPPLQLMPQSQPLPSSPAQP------PGLTQSQNLPPPPASHPPTGLHQVAPQPPFA 1035

Query: 762  STPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKF 821
              P     PPP    + P     S ST  P G G+ +  + P  G       +       
Sbjct: 1036 QHPFVPGGPPPITPPTCP-----STST-PPAGPGTSA--QPPCSGAAASGGSIAGGSSCP 1087

Query: 822  YPDTSFQED--EDYRDFEYSGPPP 843
             P    +E+  +D  + E   PPP
Sbjct: 1088 LPTVQIKEEALDDAEEPESPPPPP 1111



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 60/312 (19%)

Query: 1196 PSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTH--LPSVDLSNPFTKEAALAHA 1253
            PS    GTP    P    SA  VPP+  G   +  AP     P+  + +   ++A   H 
Sbjct: 751  PSSAPPGTPQLPTPGPTPSATAVPPQ--GSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPP-----PPPPPVDHSGVV--- 1305
              PP P      P P+P PP  P   S+   S    + PP     PP P    +G +   
Sbjct: 809  QRPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 865

Query: 1306 -----PFPAPPLAEHGVA----GAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRD 1356
                 PF  PP A  G A       A +P  H+SL              PR+   P    
Sbjct: 866  PGPPQPFGLPPQASQGQAPLGTSPAAAYP--HTSLQLPASQSALQSQQPPREQPLPPAP- 922

Query: 1357 LNGPGLSRVRESLTLPSHSLE----HLGPPHGGGGGGGSNSSSGPP---------LGPSH 1403
                 +  ++   T P   L     H  PPH  G    S +++ PP         L   H
Sbjct: 923  ---LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 979

Query: 1404 RDTISRSGIILR---SPRPDFRPREPFLSRDP-------------FHSLKRPRPPFARGP 1447
              +     + L     P P    + P L++                H +  P+PPFA+ P
Sbjct: 980  PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVA-PQPPFAQHP 1038

Query: 1448 PFFAPKRPFFPP 1459
                   P  PP
Sbjct: 1039 FVPGGPPPITPP 1050



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 120/594 (20%), Positives = 196/594 (32%), Gaps = 105/594 (17%)

Query: 408  ENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALP------NLANVDLAKISSILS 461
            ENI   + C          PP+ KPV+    P P +  P       L+     +      
Sbjct: 524  ENILLCTDCRIHFKKYGELPPIEKPVD----PPPFMFKPVKEEDDGLSGKHSMRTRRSRG 579

Query: 462  SLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESI 521
            S++++       PAS     +P +    +SG  +P+ A+T+S++  A          E++
Sbjct: 580  SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKA----------ETV 629

Query: 522  LSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSS 581
              +  K + +++  L+      + V  +   A   +S+ T     +   S  +G    S 
Sbjct: 630  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 582  AQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPS-TTFKLPSNSLGFTATHNTSPA 640
            +     +S N   +S   ++   + S      SP +PS    +  S+S          P 
Sbjct: 690  S-----RSVNDEGSSDPKDIDQDNRS-----TSPSIPSPQDNESDSDSSAQQQMLQAQPP 739

Query: 641  A--PPTEVTICQSS-EVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGS 697
            A   PT VT   SS     P+L +   +PS                     +P       
Sbjct: 740  ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATA------------------VP-----PQ 776

Query: 698  SAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKII 757
             +P+ S   +  + PT+     +  T ++   +  P +      P   S           
Sbjct: 777  GSPTASQAPNQPQAPTAP----VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGS 832

Query: 758  SPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSS 817
            +   S PS  + P  G+    P  L        P   G   P+  P    +  + L  +S
Sbjct: 833  AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP---GPPQPFGLPPQASQGQAPL-GTS 888

Query: 818  QEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYS 877
                YP TS Q        +   PP    +     PA   +   K   TT    + +  +
Sbjct: 889  PAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQA 944

Query: 878  HRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSF 937
            H+          PP +              S P     FS+  N P     P P+     
Sbjct: 945  HK---------HPPHL--------------SGP---SPFSMNANLP-----PPPALKP-- 971

Query: 938  FTPDSNHNSLSQSTTGHLSLPQKQ-YPDSPHPVPHRSLFSPQNTLAAPTGHPPT 990
             +  S H+  S        +PQ Q  P SP   P   L   QN    P  HPPT
Sbjct: 972  LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPPT 1023



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 111/532 (20%), Positives = 161/532 (30%), Gaps = 99/532 (18%)

Query: 830  DEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAF 889
            +ED R    + P  ++  + + K A+++ KS+K        P+ S+   R +        
Sbjct: 603  NEDIRSSGRNSPSAASTSSNDSK-AETVKKSAKKVKEEASSPLKSNKRQREK-------- 653

Query: 890  PPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGS---DRSPSPSKNDSFFTPDSNHNS 946
                  +   +E  DR SS        S R N P     + S S S ND   +   + + 
Sbjct: 654  ------VASDTEEADRTSSKKTKTQEIS-RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ 706

Query: 947  LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTS-----GVEKVLASTI 1001
             ++ST+  +  PQ    DS      + L +    L APTG  P       G  ++     
Sbjct: 707  DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766

Query: 1002 STTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHY 1061
            + ++T         AS+ P+      QAP+   P   +  +    P      Q+    H 
Sbjct: 767  TPSATAVPPQGSPTASQAPNQP----QAPTAPVPHTHIQQAPALHP------QRPPSPHP 816

Query: 1062 RIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGR 1121
                        L  S  +  AP      H+       G P                   
Sbjct: 817  PPHPSPHPPLQPLTGSAGQPSAPS-----HAQPPLHGQGPP------------------- 852

Query: 1122 EASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSF 1181
                 G   L         GP     L      G   L     A Y   + Q   S  + 
Sbjct: 853  -----GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 907

Query: 1182 RSNSFNSTFEHHLPPSPLE--HGTPFQREPVGPSSAPPV---PPKDHG-GIFSRDAPTHL 1235
            +S       E  LPP+PL   H  P    P+    AP     PP   G   FS +A    
Sbjct: 908  QSQQ--PPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 965

Query: 1236 PSV--DLSNPFTKEAALAHAAP--------------------------PPPPGEHSGIPF 1267
            P     LS+  T     AH  P                          PPPP  H     
Sbjct: 966  PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGL 1025

Query: 1268 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAG 1319
                P PP  +H    G   P + P  P      +G      PP +    +G
Sbjct: 1026 HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077



 Score = 38.1 bits (87), Expect = 0.063
 Identities = 125/635 (19%), Positives = 197/635 (31%), Gaps = 112/635 (17%)

Query: 705  PSDFQRGPTSTSIDNIDGTPV----RDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPG 760
            P  F   P     D + G       R   S +  +     +P S    T  +   I S G
Sbjct: 551  PPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 761  SSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQP----SDGMERPSSLMDS 816
             ++PS+  +          ++ +  V       L S    ++     ++  +R SS    
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 817  SQEKFYPDTSFQ---EDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKL----SDTTEY 869
            +QE   P++  +   E  D R     G      ++ + +     + S +     SD++  
Sbjct: 671  TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQ 730

Query: 870  QPILSSYSHRAQE-FGVK---SAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGS 925
            Q +L +     Q   GV    S+ PP    L          +  P      S   N+P +
Sbjct: 731  QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790

Query: 926  DRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPT 985
              +P P            H  + Q+   H   PQ+  P SPHP PH S   P   L    
Sbjct: 791  PTAPVP------------HTHIQQAPALH---PQR--PPSPHPPPHPSPHPPLQPLTGSA 833

Query: 986  GHP--PTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAP--SKGTPSDGVSL 1041
            G P  P+     +         +++   +L++    P   + FG  P  S+G    G   
Sbjct: 834  GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH----PGPPQPFGLPPQASQGQAPLG--- 886

Query: 1042 SNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGE 1101
                      T       H  ++   S S L       E+  P   L            +
Sbjct: 887  ----------TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI-------K 929

Query: 1102 PIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTG 1161
            P  T    ++P      H    S    F ++ +       P +   L+SL    S     
Sbjct: 930  PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP----PPALKPLSSL----STHHPP 981

Query: 1162 FKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGT----------PFQREPVG 1211
                P  +  PQ Q  + S  +     T   +LPP P  H            PF + P  
Sbjct: 982  SAHPPPLQLMPQSQP-LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040

Query: 1212 PSSAPPVPPKD------------------------HGGIFSRDAPTHLPSVDLSNPFTKE 1247
            P   PP+ P                           GG  +  +   LP+V +      +
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 1100

Query: 1248 AALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSS 1282
            A    + PPPP       P P P     P   S S
Sbjct: 1101 AEEPESPPPPPRS-----PSPEPTVVDTPSHASQS 1130



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 45/163 (27%), Positives = 53/163 (32%), Gaps = 51/163 (31%)

Query: 1188 STFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKE 1247
            S+   H PPS   H  P Q  P   S   P  P    G+       +LP    S+P T  
Sbjct: 973  SSLSTHHPPSA--HPPPLQLMP--QSQPLPSSPAQPPGLTQSQ---NLPPPPASHPPT-- 1023

Query: 1248 AALAHAAPPPPPGEHSGIPFPTPP-----------PPPPPGEH-------------SSSG 1283
              L   AP PP  +H  +P   PP           PP  PG               S +G
Sbjct: 1024 -GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAG 1082

Query: 1284 GSGVPFST-----------------PPPPPPPVDHSGVVPFPA 1309
            GS  P  T                 PPPP  P     VV  P+
Sbjct: 1083 GSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 52/178 (29%), Positives = 62/178 (34%), Gaps = 43/178 (24%)

Query: 1182 RSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLS 1241
            R   FN T  HH       H    Q++P+   SA PV P                   L 
Sbjct: 1416 RLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP-------------------LV 1456

Query: 1242 NPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDH 1301
            +P T    LA    P PPG       P P    PP EH         F TP P   P   
Sbjct: 1457 DPLTAGPHLARF--PYPPG-----TLPNPLLGQPPHEHEML--RHPVFGTPYPRDLP--- 1504

Query: 1302 SGVVPFPAPPL-AEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGG--PTQRD 1356
             G +P   PP+ A H +    A      S+ LQ    E   +   P  HGG  P+Q D
Sbjct: 1505 -GAIP---PPMSAAHQLQAMHA-----QSAELQRLAMEQQWLHGHPHMHGGHLPSQED 1553


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 131/564 (23%), Positives = 206/564 (36%), Gaps = 81/564 (14%)

Query: 314  PDPEESPVP----SPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVE 369
            PD   SP+     S   ++PS   + S        E+   + +  K     P+  N+   
Sbjct: 595  PDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPLKSNKRQR 651

Query: 370  DMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPL 429
            +   SD E+        DR      K+    S P  P+E   ++S    V    ++ P  
Sbjct: 652  EKVASDTEE-------ADRTSSKKTKTQ-EISRPNSPSEGEGESSDSRSVNDEGSSDPKD 703

Query: 430  PKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKN-TGVSPA-SRPSPGTPTSPS 487
                N S SPS      N ++ D +    +L +    ++  TGV+PA S   PGTP  P 
Sbjct: 704  IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP- 762

Query: 488  NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT 547
              T G    A A     +P A   S+    P++  + +  T  Q APAL           
Sbjct: 763  --TPGPTPSATAVPPQGSPTA---SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817

Query: 548  GNPVP------ASEAASQSTSASPANTTVSTIKGRNLPSSAQ-------PFIPKSFNYSP 594
             +P P       + +A Q ++ S A   +   +G   P S Q       P  P+ F   P
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-QGPPGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 595  NSSTSEVSSTSASKASIGQSPGL--PSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSS 652
             +S  +        A +G SP    P T+ +LP++     +        PP E  +   +
Sbjct: 877  QASQGQ--------APLGTSPAAAYPHTSLQLPASQSALQSQQ------PPREQPL-PPA 921

Query: 653  EVSKPKLESESTSPSLEMKIHNFLKGNPGFSG-----LNLNIPI------LSSLGSSAPS 701
             ++ P ++   T+P  ++      K  P  SG     +N N+P       LSSL +  P 
Sbjct: 922  PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPP 981

Query: 702  ESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGS 761
             +HP   Q  P S  + +    P         TQ + +  P +S   T         P +
Sbjct: 982  SAHPPPLQLMPQSQPLPSSPAQP------PGLTQSQNLPPPPASHPPTGLHQVAPQPPFA 1035

Query: 762  STPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKF 821
              P     PPP    + P     S ST  P G G+ +  + P  G       +       
Sbjct: 1036 QHPFVPGGPPPITPPTCP-----STST-PPAGPGTSA--QPPCSGAAASGGSIAGGSSCP 1087

Query: 822  YPDTSFQED--EDYRDFEYSGPPP 843
             P    +E+  +D  + E   PPP
Sbjct: 1088 LPTVQIKEEALDDAEEPESPPPPP 1111



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 60/312 (19%)

Query: 1196 PSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTH--LPSVDLSNPFTKEAALAHA 1253
            PS    GTP    P    SA  VPP+  G   +  AP     P+  + +   ++A   H 
Sbjct: 751  PSSAPPGTPQLPTPGPTPSATAVPPQ--GSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808

Query: 1254 APPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPP-----PPPPPVDHSGVV--- 1305
              PP P      P P+P PP  P   S+   S    + PP     PP P    +G +   
Sbjct: 809  QRPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 865

Query: 1306 -----PFPAPPLAEHGVA----GAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRD 1356
                 PF  PP A  G A       A +P  H+SL              PR+   P    
Sbjct: 866  PGPPQPFGLPPQASQGQAPLGTSPAAAYP--HTSLQLPASQSALQSQQPPREQPLPPAP- 922

Query: 1357 LNGPGLSRVRESLTLPSHSLE----HLGPPHGGGGGGGSNSSSGPP---------LGPSH 1403
                 +  ++   T P   L     H  PPH  G    S +++ PP         L   H
Sbjct: 923  ---LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 979

Query: 1404 RDTISRSGIILR---SPRPDFRPREPFLSRDP-------------FHSLKRPRPPFARGP 1447
              +     + L     P P    + P L++                H +  P+PPFA+ P
Sbjct: 980  PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVA-PQPPFAQHP 1038

Query: 1448 PFFAPKRPFFPP 1459
                   P  PP
Sbjct: 1039 FVPGGPPPITPP 1050



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 120/594 (20%), Positives = 196/594 (32%), Gaps = 105/594 (17%)

Query: 408  ENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALP------NLANVDLAKISSILS 461
            ENI   + C          PP+ KPV+    P P +  P       L+     +      
Sbjct: 524  ENILLCTDCRIHFKKYGELPPIEKPVD----PPPFMFKPVKEEDDGLSGKHSMRTRRSRG 579

Query: 462  SLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESI 521
            S++++       PAS     +P +    +SG  +P+ A+T+S++  A          E++
Sbjct: 580  SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKA----------ETV 629

Query: 522  LSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSS 581
              +  K + +++  L+      + V  +   A   +S+ T     +   S  +G    S 
Sbjct: 630  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 582  AQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPS-TTFKLPSNSLGFTATHNTSPA 640
            +     +S N   +S   ++   + S      SP +PS    +  S+S          P 
Sbjct: 690  S-----RSVNDEGSSDPKDIDQDNRS-----TSPSIPSPQDNESDSDSSAQQQMLQAQPP 739

Query: 641  A--PPTEVTICQSS-EVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGS 697
            A   PT VT   SS     P+L +   +PS                     +P       
Sbjct: 740  ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATA------------------VP-----PQ 776

Query: 698  SAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKII 757
             +P+ S   +  + PT+     +  T ++   +  P +      P   S           
Sbjct: 777  GSPTASQAPNQPQAPTAP----VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGS 832

Query: 758  SPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSS 817
            +   S PS  + P  G+    P  L        P   G   P+  P    +  + L  +S
Sbjct: 833  AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP---GPPQPFGLPPQASQGQAPL-GTS 888

Query: 818  QEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYS 877
                YP TS Q        +   PP    +     PA   +   K   TT    + +  +
Sbjct: 889  PAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQA 944

Query: 878  HRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSF 937
            H+          PP +              S P     FS+  N P     P P+     
Sbjct: 945  HK---------HPPHL--------------SGP---SPFSMNANLP-----PPPALKP-- 971

Query: 938  FTPDSNHNSLSQSTTGHLSLPQKQ-YPDSPHPVPHRSLFSPQNTLAAPTGHPPT 990
             +  S H+  S        +PQ Q  P SP   P   L   QN    P  HPPT
Sbjct: 972  LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPPT 1023



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 111/532 (20%), Positives = 161/532 (30%), Gaps = 99/532 (18%)

Query: 830  DEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAF 889
            +ED R    + P  ++  + + K A+++ KS+K        P+ S+   R +        
Sbjct: 603  NEDIRSSGRNSPSAASTSSNDSK-AETVKKSAKKVKEEASSPLKSNKRQREK-------- 653

Query: 890  PPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGS---DRSPSPSKNDSFFTPDSNHNS 946
                  +   +E  DR SS        S R N P     + S S S ND   +   + + 
Sbjct: 654  ------VASDTEEADRTSSKKTKTQEIS-RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ 706

Query: 947  LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTS-----GVEKVLASTI 1001
             ++ST+  +  PQ    DS      + L +    L APTG  P       G  ++     
Sbjct: 707  DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766

Query: 1002 STTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHY 1061
            + ++T         AS+ P+      QAP+   P   +  +    P      Q+    H 
Sbjct: 767  TPSATAVPPQGSPTASQAPNQP----QAPTAPVPHTHIQQAPALHP------QRPPSPHP 816

Query: 1062 RIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGR 1121
                        L  S  +  AP      H+       G P                   
Sbjct: 817  PPHPSPHPPLQPLTGSAGQPSAPS-----HAQPPLHGQGPP------------------- 852

Query: 1122 EASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSF 1181
                 G   L         GP     L      G   L     A Y   + Q   S  + 
Sbjct: 853  -----GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL 907

Query: 1182 RSNSFNSTFEHHLPPSPLE--HGTPFQREPVGPSSAPPV---PPKDHG-GIFSRDAPTHL 1235
            +S       E  LPP+PL   H  P    P+    AP     PP   G   FS +A    
Sbjct: 908  QSQQ--PPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP 965

Query: 1236 PSV--DLSNPFTKEAALAHAAP--------------------------PPPPGEHSGIPF 1267
            P     LS+  T     AH  P                          PPPP  H     
Sbjct: 966  PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGL 1025

Query: 1268 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAG 1319
                P PP  +H    G   P + P  P      +G      PP +    +G
Sbjct: 1026 HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077



 Score = 38.1 bits (87), Expect = 0.063
 Identities = 125/635 (19%), Positives = 197/635 (31%), Gaps = 112/635 (17%)

Query: 705  PSDFQRGPTSTSIDNIDGTPV----RDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPG 760
            P  F   P     D + G       R   S +  +     +P S    T  +   I S G
Sbjct: 551  PPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 761  SSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQP----SDGMERPSSLMDS 816
             ++PS+  +          ++ +  V       L S    ++     ++  +R SS    
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 817  SQEKFYPDTSFQ---EDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKL----SDTTEY 869
            +QE   P++  +   E  D R     G      ++ + +     + S +     SD++  
Sbjct: 671  TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQ 730

Query: 870  QPILSSYSHRAQE-FGVK---SAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGS 925
            Q +L +     Q   GV    S+ PP    L          +  P      S   N+P +
Sbjct: 731  QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790

Query: 926  DRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPT 985
              +P P            H  + Q+   H   PQ+  P SPHP PH S   P   L    
Sbjct: 791  PTAPVP------------HTHIQQAPALH---PQR--PPSPHPPPHPSPHPPLQPLTGSA 833

Query: 986  GHP--PTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAP--SKGTPSDGVSL 1041
            G P  P+     +         +++   +L++    P   + FG  P  S+G    G   
Sbjct: 834  GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH----PGPPQPFGLPPQASQGQAPLG--- 886

Query: 1042 SNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGE 1101
                      T       H  ++   S S L       E+  P   L            +
Sbjct: 887  ----------TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI-------K 929

Query: 1102 PIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTG 1161
            P  T    ++P      H    S    F ++ +       P +   L+SL    S     
Sbjct: 930  PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP----PPALKPLSSL----STHHPP 981

Query: 1162 FKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGT----------PFQREPVG 1211
                P  +  PQ Q  + S  +     T   +LPP P  H            PF + P  
Sbjct: 982  SAHPPPLQLMPQSQP-LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040

Query: 1212 PSSAPPVPPKD------------------------HGGIFSRDAPTHLPSVDLSNPFTKE 1247
            P   PP+ P                           GG  +  +   LP+V +      +
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 1100

Query: 1248 AALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSS 1282
            A    + PPPP       P P P     P   S S
Sbjct: 1101 AEEPESPPPPPRS-----PSPEPTVVDTPSHASQS 1130



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 45/163 (27%), Positives = 53/163 (32%), Gaps = 51/163 (31%)

Query: 1188 STFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKE 1247
            S+   H PPS   H  P Q  P   S   P  P    G+       +LP    S+P T  
Sbjct: 973  SSLSTHHPPSA--HPPPLQLMP--QSQPLPSSPAQPPGLTQSQ---NLPPPPASHPPT-- 1023

Query: 1248 AALAHAAPPPPPGEHSGIPFPTPP-----------PPPPPGEH-------------SSSG 1283
              L   AP PP  +H  +P   PP           PP  PG               S +G
Sbjct: 1024 -GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAG 1082

Query: 1284 GSGVPFST-----------------PPPPPPPVDHSGVVPFPA 1309
            GS  P  T                 PPPP  P     VV  P+
Sbjct: 1083 GSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS 1125



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 52/178 (29%), Positives = 62/178 (34%), Gaps = 43/178 (24%)

Query: 1182 RSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLS 1241
            R   FN T  HH       H    Q++P+   SA PV P                   L 
Sbjct: 1416 RLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP-------------------LV 1456

Query: 1242 NPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDH 1301
            +P T    LA    P PPG       P P    PP EH         F TP P   P   
Sbjct: 1457 DPLTAGPHLARF--PYPPG-----TLPNPLLGQPPHEHEML--RHPVFGTPYPRDLP--- 1504

Query: 1302 SGVVPFPAPPL-AEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGG--PTQRD 1356
             G +P   PP+ A H +    A      S+ LQ    E   +   P  HGG  P+Q D
Sbjct: 1505 -GAIP---PPMSAAHQLQAMHA-----QSAELQRLAMEQQWLHGHPHMHGGHLPSQED 1553


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
           [Homo sapiens]
          Length = 909

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 118/507 (23%), Positives = 186/507 (36%), Gaps = 64/507 (12%)

Query: 318 ESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVE 377
           E+P  S      S T +E+P        S   T E+   +TP   +  R  E    S   
Sbjct: 90  ETPSHSTPSYTTSITTTETPSHSTPSFTSSITTTETTSHSTPSFTSSIRTTETTSYSTPS 149

Query: 378 DDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSL 437
              S  I E             T+  T  +   S +SS T    T  +TP     + T+ 
Sbjct: 150 FTSSNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTE 209

Query: 438 SPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPA 497
           + S +      +       S    S TS      ++ +  PS  TP+S S +T+      
Sbjct: 210 TTSHSTPSFTSSITTTETTSHDTPSFTS-----SITTSETPSHSTPSSTSLITT------ 258

Query: 498 PATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT--------GN 549
              TTSH+           TP S  S+++ T+T S  A    SS+  + T         +
Sbjct: 259 -TKTTSHS-----------TP-SFTSSITTTETTSHSAHSFTSSITTTETTSHNTRSFTS 305

Query: 550 PVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKA 609
            +  +E  S ST++  ++ T +     + PS +               TSE + T     
Sbjct: 306 SITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTPVT 365

Query: 610 SIGQSPGLPSTTFK-LPSNSLGFTATHNTSPAAP--PTEVTICQSSEVSKPKLESESTSP 666
               S  +P+T+ + L  +S+G + +  T+   P  PT+++   +      +    S+SP
Sbjct: 366 PSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPT------RTHIISSSP 419

Query: 667 SLEMKIHNFLKG--NPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTP 724
           S++    + L G  +P  S + + + I  +   S+ S S        PT T        P
Sbjct: 420 SIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVV-IPETPTQT-------PP 471

Query: 725 VRDERSGT---PTQDEMMDKPTSSSVDTM------SLLSKIIS----PGSSTPSSTRSPP 771
           V    +GT   P    +    T SS  T+      + LS I+S    P  ST SST    
Sbjct: 472 VLTSATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTT 531

Query: 772 PGRDESYPRELSNSVSTYRPFGLGSES 798
           P          S S  T   F  GS S
Sbjct: 532 PSTPSLQTSLTSTSEFTTESFTRGSTS 558



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 103/414 (24%), Positives = 165/414 (39%), Gaps = 66/414 (15%)

Query: 392 PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTAT-PPLPKPVNTS------LSPSPALA 444
           P   S++ST +PT     ++ +S  T   +T T   P +P  ++T       +S SP++ 
Sbjct: 363 PVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQ 422

Query: 445 LPNLANVDLAKISSILSSLTSVMKNTGVSPASRPS------PGTPT-SPSNLTSGLKT-- 495
               +++ +   S  +S++   ++ T  +P S  S      P TPT +P  LTS   T  
Sbjct: 423 STETSSL-VGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQT 481

Query: 496 -PAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP---- 550
            PAP T T  +  ++  +   +TP + LS +  T     P+    SS LQ+    P    
Sbjct: 482 SPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTH--SSTLQTTPSTPSLQT 539

Query: 551 --VPASEAASQS-----TSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSS 603
                SE  ++S     TS +   T+ STI   + P+      P S + +P  ST+  S 
Sbjct: 540 SLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSV 599

Query: 604 TSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESES 663
            S+      ++ G  S T     +S   T+T +TS +       I   S +S P     S
Sbjct: 600 PSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLP-----S 654

Query: 664 TSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGT 723
           T+P             PG     + I I+ +  +    E  PS     P +T +      
Sbjct: 655 TTPC------------PG----TITITIVPASPTDPCVEMDPSTEATSPPTTPL------ 692

Query: 724 PVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES 777
                 +  P   EM+  PTS S+ T   L+  +   S  P S  S  P    S
Sbjct: 693 ------TVFPFTTEMVTCPTSISIQT--TLTTYMDTSSMMPESESSISPNASSS 738



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 102/462 (22%), Positives = 177/462 (38%), Gaps = 46/462 (9%)

Query: 332 TGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEK 391
           T SE+P        S   T E+  S+TP   +     E    S      S    E     
Sbjct: 2   TTSETPSHRTPSFTSSITTTETPSSSTPSFTSSITTTETTSHSTPSFTSSISTTETTSHS 61

Query: 392 PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANV 451
               +++ T   T      S  +S T       +TP     + T+ +PS +      +  
Sbjct: 62  TPSFTSLITITETTSHSTPSYTTSITTTETPSHSTPSYTTSITTTETPSHSTPSFTSSIT 121

Query: 452 DLAKISSILSSLTSVMKNTGVSPASRPS---------PGTPTSPSNLTSGLKTPAPATTT 502
                S    S TS ++ T  +  S PS           + ++PS +TS   T  P+++T
Sbjct: 122 TTETTSHSTPSFTSSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSST 181

Query: 503 SHNPLANILSKVEITPES---ILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQ 559
                ++ ++  E T  S     S+++ T+T S       SS+  + T +    S  +S 
Sbjct: 182 P--SFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSI 239

Query: 560 STSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPS 619
           +TS +P+++T S        S++     K+ ++S  S TS +++T  +  S        +
Sbjct: 240 TTSETPSHSTPS--------STSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSIT 291

Query: 620 TTFKLPSNSLGFTA------THNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIH 673
           TT     N+  FT+      T++ S  +  + +T  +++  S P   S  T+        
Sbjct: 292 TTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXX 351

Query: 674 NFLKGNPGF------SGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTP-VR 726
                          S L+ +IP  +SL +  PS           TSTS+      P + 
Sbjct: 352 XXTSETAVTPTPVTPSSLSTDIP-TTSLRTLTPSSV--------GTSTSLTTTTDFPSIP 402

Query: 727 DERSGTPTQDEMM-DKPTSSSVDTMSLLSKIISPGSSTPSST 767
            + S  PT+  ++   P+  S +T SL+    SP  ST   T
Sbjct: 403 TDISTLPTRTHIISSSPSIQSTETSSLVG-TTSPTMSTVRMT 443



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 36/407 (8%)

Query: 396 SAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPAL----ALPNLANV 451
           S  +T  P+  T + +  SS T    T  +TP     ++T+ + S +     +L  +   
Sbjct: 17  SITTTETPSSSTPSFT--SSITTTETTSHSTPSFTSSISTTETTSHSTPSFTSLITITET 74

Query: 452 DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANIL 511
                 S  +S+T+    +  +P+   S  T  +PS+ T    +    T T+ +   +  
Sbjct: 75  TSHSTPSYTTSITTTETPSHSTPSYTTSITTTETPSHSTPSFTSSITTTETTSHSTPSFT 134

Query: 512 SKVEITPESILSALSKTQTQSAPALQGLS--SLLQSVTGNPVPASEAASQSTSASPANTT 569
           S +  T  +  S  S T + +       S  S + S+T    P+S   S S+S +   TT
Sbjct: 135 SSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTETT 194

Query: 570 -------VSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTF 622
                   S+I      S + P    S   +  +S    S TS+   S   S   PS+T 
Sbjct: 195 SHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSITTSETPSHSTPSSTS 254

Query: 623 KLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGF 682
            +       T T  TS + P    +I  +   S       S+  + E   HN        
Sbjct: 255 LI-------TTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTETTSHNTRSFTSSI 307

Query: 683 SGLNLNIPILSSLGSS---APSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMM 739
           +    N    +S  SS     + SH +       +T+           E + TPT     
Sbjct: 308 TTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTP---- 363

Query: 740 DKPTSSSVDTMSLLSKIISP---GSSTPSSTRSPPPGRDESYPRELS 783
             P+S S D  +   + ++P   G+ST  +T +  P    S P ++S
Sbjct: 364 VTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFP----SIPTDIS 406



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 42/196 (21%), Positives = 76/196 (38%), Gaps = 21/196 (10%)

Query: 392 PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANV 451
           P   +   T VP  PT+       C  +  +  AT P   P+      +  +  P   ++
Sbjct: 657 PCPGTITITIVPASPTD------PCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISI 710

Query: 452 DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSN-LTSGLKTPAPATTTSHNPLANI 510
                + + +S       + +SP +  S GT T P+N + +  + P   T  S++ +  +
Sbjct: 711 QTTLTTYMDTSSMMPESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPL 770

Query: 511 ----LSKVEIT--PESILSALSKTQTQS---APALQGLSSLLQSVTGNPVP-----ASEA 556
               +S + +T  P S L  + +T ++S   +P     S    + T  P        +  
Sbjct: 771 PLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRI 830

Query: 557 ASQSTSASPANTTVST 572
            SQ T+ S   TT  T
Sbjct: 831 TSQMTTQSTLTTTAGT 846


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 103/414 (24%), Positives = 165/414 (39%), Gaps = 66/414 (15%)

Query: 392  PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTAT-PPLPKPVNTS------LSPSPALA 444
            P   S++ST +PT     ++ +S  T   +T T   P +P  ++T       +S SP++ 
Sbjct: 637  PVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQ 696

Query: 445  LPNLANVDLAKISSILSSLTSVMKNTGVSPASRPS------PGTPT-SPSNLTSGLKT-- 495
                +++ +   S  +S++   ++ T  +P S  S      P TPT +P  LTS   T  
Sbjct: 697  STETSSL-VGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQT 755

Query: 496  -PAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNP---- 550
             PAP T T  +  ++  +   +TP + LS +  T     P+    SS LQ+    P    
Sbjct: 756  SPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTH--SSTLQTTPSTPSLQT 813

Query: 551  --VPASEAASQS-----TSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSS 603
                 SE  ++S     TS +   T+ STI   + P+      P S + +P  ST+  S 
Sbjct: 814  SLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSV 873

Query: 604  TSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESES 663
             S+      ++ G  S T     +S   T+T +TS +       I   S +S P     S
Sbjct: 874  PSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLP-----S 928

Query: 664  TSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGT 723
            T+P             PG     + I I+ +  +    E  PS     P +T +      
Sbjct: 929  TTPC------------PG----TITITIVPASPTDPCVEMDPSTEATSPPTTPL------ 966

Query: 724  PVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES 777
                  +  P   EM+  PTS S+ T   L+  +   S  P S  S  P    S
Sbjct: 967  ------TVFPFTTEMVTCPTSISIQT--TLTTYMDTSSMMPESESSISPNASSS 1012



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 152/712 (21%), Positives = 282/712 (39%), Gaps = 113/712 (15%)

Query: 396  SAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAK 455
            S  ST V  KP   ++   S T      +A    P       +P   +   +++  D   
Sbjct: 156  SYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSVSATD--- 212

Query: 456  ISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVE 515
             ++  ++++S  + T  +P    S  T TSP+ + + LKT      TS +P+ +      
Sbjct: 213  -TTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKT----AVTSTSPITS-----S 262

Query: 516  ITPESILSALSKTQTQSAPALQGLSSLLQSV-TGNPVPASEAASQS-TSASPANTTVSTI 573
            IT  + +++++ T +Q   A   LSS  +++ +  PV ++E  +   T+ +P +T V+T 
Sbjct: 263  ITSTNTVTSMTTTASQPT-ATNTLSSPTRTILSSTPVLSTETITSGITNTTPLSTLVTT- 320

Query: 574  KGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTA 633
                LP++     P S    P S TS V+ ++   A                  S   T 
Sbjct: 321  ----LPTTISRSTPTSETTYPTSPTSTVTDSTTKIA-----------------YSTSMTG 359

Query: 634  THNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILS 693
            T +T  + PPT  ++  +   + P     +T  + E+  H+     P FS         S
Sbjct: 360  TLSTETSLPPTSSSLPTTETATTPMTNLVTT--TTEISSHS----TPSFSS--------S 405

Query: 694  SLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLL 753
            ++ S+  S S P  F    T+T   +   TP R   S T T+      P+ +     SL+
Sbjct: 406  TIYSTVTSHSTPR-FTSSITTTETPS-HSTP-RFTSSFTNTKTTSHRSPSFT-----SLI 457

Query: 754  SKIISPGSSTPSSTRSPPPGRDESY-PRELSNSVSTYRPFGLGSESPYKQPSDGMERPSS 812
            +   +   STPS T S       S+  R  ++S++T            +  S      +S
Sbjct: 458  TTTETTSHSTPSFTSSITTTETTSHSARSFTSSITT-----------TETTSHNTRSFTS 506

Query: 813  LMDSSQEKFYPDTSFQED-EDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQP 871
             + +++   +  TSF           +S P  S+ +   + P  S    +    TT+   
Sbjct: 507  SITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTK--- 563

Query: 872  ILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSP 931
                           S   P + + + ++E      S+PG     S+   E  S+ +PS 
Sbjct: 564  -------------TTSHITPGLTSSITTTETTSH--STPGF--TSSITTTETTSESTPSL 606

Query: 932  SKNDSFFTPDSNHNSL-SQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPT 990
            S +  + T  ++  ++ S  TT   ++       +P PV   SL +   T +  T  P +
Sbjct: 607  SSSTIYSTVSTSTTAITSHFTTSETAV-------TPTPVTPSSLSTDIPTTSLRTLTPSS 659

Query: 991  SGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLT 1050
             G      ++ S T+T +F ++  + S  P+       +PS  + ++  SL   T P+++
Sbjct: 660  VG------TSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQS-TETSSLVGTTSPTMS 712

Query: 1051 ATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEP 1102
                  +       +  S+S + +P+ T  +  P+ T    SA+  + S  P
Sbjct: 713  TVRMTLRITENTPISSFSTSIVVIPE-TPTQTPPVLT----SATGTQTSPAP 759



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 94/400 (23%), Positives = 166/400 (41%), Gaps = 59/400 (14%)

Query: 395 KSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLA 454
           K A STS+    +   S   + + +P T TAT P+   V T+   S + + P+ ++   +
Sbjct: 350 KIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEIS-SHSTPSFSS---S 405

Query: 455 KISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHN--PLANILS 512
            I S ++S ++    + ++    PS  TP   S+ T+         TTSH      ++++
Sbjct: 406 TIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTN-------TKTTSHRSPSFTSLIT 458

Query: 513 KVEITPE---SILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTT 569
             E T     S  S+++ T+T S  A    SS+  + T +    S  +S +T+ + +++T
Sbjct: 459 TTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHST 518

Query: 570 VSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPS-------TTF 622
            S         +           + +S+ S  SS + ++  +  +PGL S       T+ 
Sbjct: 519 TSFTSSITTTET-----------TSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSH 567

Query: 623 KLPSNSLGFTATHNTSPAAP--PTEVTICQSSEVSKPKLES----ESTSPSLEMKIHNFL 676
             P  +   T T  TS + P   + +T  +++  S P L S     + S S      +F 
Sbjct: 568 ITPGLTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFT 627

Query: 677 KGNPGF-------SGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTP-VRDE 728
                        S L+ +IP  +SL +  PS           TSTS+      P +  +
Sbjct: 628 TSETAVTPTPVTPSSLSTDIP-TTSLRTLTPSSV--------GTSTSLTTTTDFPSIPTD 678

Query: 729 RSGTPTQDEMM-DKPTSSSVDTMSLLSKIISPGSSTPSST 767
            S  PT+  ++   P+  S +T SL+    SP  ST   T
Sbjct: 679 ISTLPTRTHIISSSPSIQSTETSSLVG-TTSPTMSTVRMT 717



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 42/196 (21%), Positives = 76/196 (38%), Gaps = 21/196 (10%)

Query: 392  PAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANV 451
            P   +   T VP  PT+       C  +  +  AT P   P+      +  +  P   ++
Sbjct: 931  PCPGTITITIVPASPTD------PCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISI 984

Query: 452  DLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSN-LTSGLKTPAPATTTSHNPLANI 510
                 + + +S       + +SP +  S GT T P+N + +  + P   T  S++ +  +
Sbjct: 985  QTTLTTYMDTSSMMPESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPL 1044

Query: 511  ----LSKVEIT--PESILSALSKTQTQS---APALQGLSSLLQSVTGNPVP-----ASEA 556
                +S + +T  P S L  + +T ++S   +P     S    + T  P        +  
Sbjct: 1045 PLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRI 1104

Query: 557  ASQSTSASPANTTVST 572
             SQ T+ S   TT  T
Sbjct: 1105 TSQMTTQSTLTTTAGT 1120



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 112/561 (19%), Positives = 185/561 (32%), Gaps = 70/561 (12%)

Query: 531  QSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTV-----------STIKG--RN 577
            +++P   G  S   S++  P P +EAAS   S SP +  +           S   G   N
Sbjct: 14   KASPWATGTLSTATSISQVPFPRAEAASAVLSNSPHSRDLAGWPLGVPQLASPAPGHREN 73

Query: 578  LP-----SSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPG----LPSTTFKLPSNS 628
             P     S     I ++   SP SS +  + TS     +  +P       +TT  +   S
Sbjct: 74   APMTLTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTS 133

Query: 629  LGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGF-SGLNL 687
               T +H TS     T+V    SS  S P  +   T+ +    +    KG     S  + 
Sbjct: 134  FIITISHPTSICVTTTQVAF-TSSYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPST 192

Query: 688  NIPILSSLGSSAPSESHPSDFQRGPT-STSIDNIDGTP-----VRDERSGTPTQDEMMDK 741
                 + + +  PS    +D     T S++    + TP     +    S TP    +   
Sbjct: 193  TTARETPIVTVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKTA 252

Query: 742  PTSSS------VDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLG 795
             TS+S        T ++ S   +    T ++T S P     S    LS    T    G+ 
Sbjct: 253  VTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETIT---SGIT 309

Query: 796  SESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAK 855
            + +P       +    S    + E  YP +                P S + +   K A 
Sbjct: 310  NTTPLSTLVTTLPTTISRSTPTSETTYPTS----------------PTSTVTDSTTKIAY 353

Query: 856  SILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGA 915
            S   +  LS  T   P  SS          ++A  P    +  ++E     + S      
Sbjct: 354  STSMTGTLSTETSLPPTSSSLP------TTETATTPMTNLVTTTTEISSHSTPSFSSSTI 407

Query: 916  FS--VRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRS 973
            +S     + P    S + ++  S  TP    +  +  TT H S        +     H +
Sbjct: 408  YSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHST 467

Query: 974  -LFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHF------ 1026
              F+   T    T H   S    +  +  ++ +T  F + +            F      
Sbjct: 468  PSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITT 527

Query: 1027 GQAPSKGTPSDGVSLSNLTQP 1047
             +  S  TPS   S++    P
Sbjct: 528  TETTSHSTPSFSSSITTTETP 548


>gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo
           sapiens]
          Length = 514

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 112/487 (22%), Positives = 197/487 (40%), Gaps = 60/487 (12%)

Query: 310 KSTLPDPEESPVP-----SPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTD 364
           + +L  P  S  P     +P+    S T   SP        + S    S  S+T  P TD
Sbjct: 39  RESLMTPMTSTTPITSAITPTNTVTSMTTMTSPPTTTNSNSTLSSLTSSILSSTLVPSTD 98

Query: 365 NRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMT 424
                   L+      + +     +  P  +    T+ PT PT  +  +++      +MT
Sbjct: 99  MITSHTTNLTRSSPLLATLPTTITRSTPTSE----TTYPTSPTSTVKGSTTSIRYSTSMT 154

Query: 425 ATPPLP---KPVNTSLSPSPALALP--NLANVDLAKISSILSSLTSVMKNTGVSPASRPS 479
            T  +     P ++SL  +     P  NL   ++    S  S  +S + +T  +P +  S
Sbjct: 155 GTLSMETSLPPTSSSLPTTETATTPTTNLVTTEITS-HSTPSFSSSTIHSTVSTPTTVIS 213

Query: 480 PGTPTS----------PSNLTSGLKTPAPATTTSHN--PLANILSKVEITPE---SILSA 524
            G PTS          PS+L++ +    P T T H+     ++L+  ++T     S  SA
Sbjct: 214 SGPPTSGTIVTSITVTPSSLSTDIPLTTPTTITHHSVGSTESLLTATDLTSTFTVSSSSA 273

Query: 525 LSKTQTQSAPALQGL-SSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQ 583
           +S +   S+P++Q   +S L S+T   +P+      ST  +  ++ ++T  G    SS+ 
Sbjct: 274 MSTSDIPSSPSIQNTETSSLVSMTSATIPSVRPTFTSTHNTLTSSLLTTFPGTYSFSSSM 333

Query: 584 PFIPKSFNYSPN-----SSTSEVSSTSAS-KASIGQSPGLPSTTFKLPSNSLGFTATHNT 637
                   ++       +STS + +T+ S  A    +    STT + PS+S+  T+T  T
Sbjct: 334 SASSDGTTHTETITSLPASTSTLHTTAESTTAHTTTTSFTTSTTMESPSSSVATTSTGQT 393

Query: 638 ---SPAAPPTE-VTICQSSEVSKPKLESESTS-PSLEMKI------------HNFLKGNP 680
              S  A  TE  T+  +++ S+  L +  TS P +   I             ++     
Sbjct: 394 TFSSSTATFTETTTLTPTTDFSEETLTTAMTSTPPITSSITPTNTVTSMTTMTSWPTATN 453

Query: 681 GFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMD 740
             S L  NI   + + S+  + SH ++    P ST +  +  T  R     TPT +    
Sbjct: 454 TLSSLTTNILSSTPVPSTERTTSHTTNI--NPVSTLVTTLPTTITR----STPTAETTYP 507

Query: 741 KPTSSSV 747
             ++S+V
Sbjct: 508 ISSTSTV 514



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 104/427 (24%), Positives = 166/427 (38%), Gaps = 64/427 (14%)

Query: 399 STSVPTKPTENISKASSCTPVPVTMTATP-----------PLPK---------PVNTSLS 438
           S+SV    T   +  SS    P T+T TP           P+           P NT  S
Sbjct: 5   SSSVAATDTGQTTFTSSTATFPETITLTPNTNMSRESLMTPMTSTTPITSAITPTNTVTS 64

Query: 439 PSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPA-----------SRPSPGTPTSPS 487
            +   + P   N      +S LSSLTS + ++ + P+           +R SP   T P+
Sbjct: 65  MTTMTSPPTTTN-----SNSTLSSLTSSILSSTLVPSTDMITSHTTNLTRSSPLLATLPT 119

Query: 488 NLTSGLKTPAPATTTSHNPLANIL-SKVEITPESILSALSKTQTQSAPALQGLSSLLQSV 546
            +T    TP   TT   +P + +  S   I   + ++     +T   P    L +   + 
Sbjct: 120 TITR--STPTSETTYPTSPTSTVKGSTTSIRYSTSMTGTLSMETSLPPTSSSLPTTETAT 177

Query: 547 TGNP-VPASEAASQSTSASPANTTVSTIKGRNLPSSAQP----FIPKSFNYSPNSSTSEV 601
           T    +  +E  S ST +  ++T  ST+       S+ P     I  S   +P+S ++++
Sbjct: 178 TPTTNLVTTEITSHSTPSFSSSTIHSTVSTPTTVISSGPPTSGTIVTSITVTPSSLSTDI 237

Query: 602 ---SSTSASKASIGQSPGL-----PSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSE 653
              + T+ +  S+G +  L      ++TF + S+S   T+   +SP+   TE     SS 
Sbjct: 238 PLTTPTTITHHSVGSTESLLTATDLTSTFTVSSSSAMSTSDIPSSPSIQNTET----SSL 293

Query: 654 VSKPKLESESTSPSLEMKIHNFLKGN--PGFSGLNLNIPILSSLGSSAPSESHPSDFQRG 711
           VS       S  P+     HN L  +    F G        SS+ +S+   +H       
Sbjct: 294 VSMTSATIPSVRPTF-TSTHNTLTSSLLTTFPG---TYSFSSSMSASSDGTTHTETITSL 349

Query: 712 PTSTSIDNIDGTPVRDERSGTP-TQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSP 770
           P STS  +          + T  T    M+ P SSSV T S      S  ++T + T + 
Sbjct: 350 PASTSTLHTTAESTTAHTTTTSFTTSTTMESP-SSSVATTSTGQTTFSSSTATFTETTTL 408

Query: 771 PPGRDES 777
            P  D S
Sbjct: 409 TPTTDFS 415


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens]
          Length = 505

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 47/121 (38%), Positives = 49/121 (40%), Gaps = 25/121 (20%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            PP P   G P    P   +S PP PP        R AP   PS               AA
Sbjct: 278  PPPPPSRGGPPPPPPPPHNSGPPPPPAR-----GRGAPPPPPS-----------RAPTAA 321

Query: 1255 PPPPPGEHSGIPFPTPPP----PPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAP 1310
            PPPPP     +  P PPP    PPPP    SS  SG     PPPPPP V   G V  P P
Sbjct: 322  PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSG-----PPPPPPSVLGVGPVAPPPP 376

Query: 1311 P 1311
            P
Sbjct: 377  P 377



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 52/164 (31%), Positives = 59/164 (35%), Gaps = 27/164 (16%)

Query: 1215 APPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTP---- 1270
            APP PP   GG      P H                 ++ PPPPP    G P P P    
Sbjct: 276  APPPPPPSRGGPPPPPPPPH-----------------NSGPPPPPARGRGAPPPPPSRAP 318

Query: 1271 ---PPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD 1327
               PPPPPP   S +     P    PPPPP +  S     P PP +  GV G VA  P  
Sbjct: 319  TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV-GPVAPPPPP 377

Query: 1328 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTL 1371
                  G        LP   DH  PT        L ++RE   L
Sbjct: 378  PPPPPPGPPPP--PGLPSDGDHQVPTTAGNKAALLDQIREGAQL 419



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 30/68 (44%), Positives = 30/68 (44%), Gaps = 7/68 (10%)

Query: 1250 LAHAAPPPPPGEHSGIPFPTPPP----PPPPGEHSSSGGSGVPFSTP---PPPPPPVDHS 1302
            L   APPPPP    G P P PPP    PPPP           P   P   PPPPPP   S
Sbjct: 272  LRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS 331

Query: 1303 GVVPFPAP 1310
              VP P P
Sbjct: 332  VAVPPPPP 339



 Score = 38.5 bits (88), Expect = 0.048
 Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 3/80 (3%)

Query: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
            PPS      P    P  PS A P PP +         P  LPS   S P     ++    
Sbjct: 313  PPSRAPTAAPPPPPPSRPSVAVPPPPPNR---MYPPPPPALPSSAPSGPPPPPPSVLGVG 369

Query: 1255 PPPPPGEHSGIPFPTPPPPP 1274
            P  PP      P P PPPPP
Sbjct: 370  PVAPPPPPPPPPPPGPPPPP 389



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 52/257 (20%), Positives = 83/257 (32%), Gaps = 41/257 (15%)

Query: 207 IELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS----SKLEEF--------- 253
           +++K  +++T R        +   K+K  GK   K   +A     S  +           
Sbjct: 162 VDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNT 221

Query: 254 ---VNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLK 310
              +N LD ++KN        +  GI  EAQ K+ +     Y  F  +   ++   ++L+
Sbjct: 222 GFDLNNLDPELKN------LFDMCGIS-EAQLKDRETSKVIYD-FIEKTGGVEAVKNELR 273

Query: 311 STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVED 370
              P P       P    P P  S  P     G  +  P      +A P P   +R    
Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVA 333

Query: 371 MELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLP 430
           +                 +  P    A+ +S P+ P           PV       PP P
Sbjct: 334 VPPP-----------PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPV------APPPP 376

Query: 431 KPVNTSLSPSPALALPN 447
            P      P P   LP+
Sbjct: 377 PPPPPPPGPPPPPGLPS 393


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 673

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 175/800 (21%), Positives = 278/800 (34%), Gaps = 155/800 (19%)

Query: 518  PESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRN 577
            P    S  S T+T S  +L G  S   S+TG P  AS   + S ++       +++KG  
Sbjct: 4    PTRTPSRASPTRTPSTASLTGTPSRA-SLTGTPSTASLMGTPSRASLTGTPPRASLKGTT 62

Query: 578  LPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSL---GFTAT 634
              S A   +  S        +S + + + S AS+ + P   S T  LP  SL     TA+
Sbjct: 63   --SMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTAS 120

Query: 635  HNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSS 694
               SP+         ++S  + P   S S +PS               +   L +P  +S
Sbjct: 121  LTRSPS---------RASLTTTPSRASLSMTPS---------------TAAALTMPSRAS 156

Query: 695  LGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSV---DTMS 751
            L  + P  S        P++ S+     TP R   +G P++      P+++S+   D+ +
Sbjct: 157  LTRTPPRAS----LTMTPSTASLTR---TPPRASPTGMPSRTSPTGMPSTASLTKMDSTA 209

Query: 752  LLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPS 811
             +++ +S  S T +  R+ P G   S PR    S+S      L   +P +    GM   +
Sbjct: 210  SITRTLSRASPTGTPPRASPTG---SPPRA---SLSMMPSTALLIRTPPRASPTGMLSRT 263

Query: 812  SL--MDSS----QEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKS----S 861
            SL  MDS+    +    P T+       R      P  +++M +  + + + + S    +
Sbjct: 264  SLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLT 323

Query: 862  KLSDT-----TEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAF 916
            K+  T     T  +  ++    RA   G  S   P+      S       +S  GL    
Sbjct: 324  KMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTA 383

Query: 917  SVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLS---LPQKQYPDSPHPVPHRS 973
            S  G  P +  + +PS      T          S TG LS   + +     SP   P R+
Sbjct: 384  SPTGTPPRASPTGTPS------TASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRA 437

Query: 974  LFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKG 1033
              +     A+PTG P         AS   T ST        + +  PS     G +PS  
Sbjct: 438  SPTGTPPRASPTGTPSR-------ASPTGTQSTA-------SPTGSPSTASPTG-SPSTA 482

Query: 1034 TPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSA 1093
            +P+   S ++LT+    A+  + +       T   +S    P +    G+P   L   S 
Sbjct: 483  SPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSP 542

Query: 1094 SNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGG 1153
            S   ++  P                               S +S    PS AS       
Sbjct: 543  SRAALTRTP-------------------------------SRASLTRTPSRAS------- 564

Query: 1154 GGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPS 1213
                      T P +    +   +V   R           +PPS    G P +  P G  
Sbjct: 565  ---------LTTPSRASLTRTPSTVLLTR-----------MPPSASPTGMPSRTSPTGMP 604

Query: 1214 SAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPP 1273
            S+  +   D     +R  P   P        T+    A     PP    +G    TPP  
Sbjct: 605  SSALLTKMDSTASITRTPPRASP--------TETPPRASPTGTPPRASPTG----TPPRA 652

Query: 1274 PPPGEHSSSGGSGVPFSTPP 1293
             P G    +  +G P    P
Sbjct: 653  SPTGTPPRASPTGTPSRASP 672



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 110/456 (24%), Positives = 177/456 (38%), Gaps = 59/456 (12%)

Query: 392 PAEKSAVSTSVPTKPTENISKASSC-TPVPVTMTATPPLPKPVNTSLSPSPALALPNLAN 450
           P+  S   T      T   S AS   TP   ++T TPP      T+ S +  +  P+ A+
Sbjct: 17  PSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTT-SMASLMVSPSRAS 75

Query: 451 VDLAKISSILSSLTSVMKNTGVSPA-------------------------SRPSPGTPTS 485
           +   + SS+L+   S+     + P                          SR S  T  S
Sbjct: 76  LTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTTPS 135

Query: 486 PSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQS 545
            ++L+    T A  T  S   L     +  +T     ++L++T  +++P   G+ S   S
Sbjct: 136 RASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPT--GMPSRT-S 192

Query: 546 VTGNPVPASEAASQSTS--------ASPANTTVSTIKGRNLPSSAQPFIPKS---FNYSP 594
            TG P  AS     ST+        ASP  T        + P ++   +P +       P
Sbjct: 193 PTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPP 252

Query: 595 NSS-TSEVSSTSASK----ASIGQSPGLPSTTFKLPSNS-LGFTATHNTS------PAAP 642
            +S T  +S TS +K    ASI ++P  PST     + S    + T +T+      P A 
Sbjct: 253 RASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRAS 312

Query: 643 PTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSE 702
           PT + + ++S        S S +P          + +P  +G         +   ++P+ 
Sbjct: 313 PTGM-LSRTSLTKMDSTASISRTPPRASITRTPSRASP--TGKPSTASPTGTPSRASPTG 369

Query: 703 SHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSS 762
           S  +    G +ST+     GTP R   +GTP+   +  KP  +S  T  L    I+   S
Sbjct: 370 SPSTASLTGLSSTASPT--GTPPRASPTGTPSTASLTRKPPRAS-PTGMLSRTSITKMDS 426

Query: 763 TPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSES 798
           T S TR+PP       P   S + +  R    G++S
Sbjct: 427 TASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQS 462



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 159/695 (22%), Positives = 247/695 (35%), Gaps = 133/695 (19%)

Query: 474  PASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSA 533
            P   PS  +PT   +  S   TP+ A+ T     A+++     TP    S  S T T   
Sbjct: 4    PTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASLMG----TP----SRASLTGTPPR 55

Query: 534  PALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIK--------GRNLPSSAQPF 585
             +L+G +S + S+  +P  AS    QS+S      +++++K         R LP ++   
Sbjct: 56   ASLKGTTS-MASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMR 114

Query: 586  IPK--SFNYSPN----------SSTSEVSSTSA-----SKASIGQSPGLPSTTFKLPSNS 628
             P   S   SP+          +S S   ST+A     S+AS+ ++P   S T    + S
Sbjct: 115  RPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTAS 174

Query: 629  LGFTATH--------NTSPAAPPTEVTIC----------------------QSSEVSKPK 658
            L  T            TSP   P+  ++                       ++S    P 
Sbjct: 175  LTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPP 234

Query: 659  LESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSID 718
              S S  PS  + I    + +P  +G+ L+   L+ + S+A          R P+  S  
Sbjct: 235  RASLSMMPSTALLIRTPPRASP--TGM-LSRTSLTKMDSTA-------SITRTPSRPSTA 284

Query: 719  NIDGTPVRDERSGTPTQDEMMDK-PTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDES 777
            +  GTP R   S TP+   +M   P +S    +S  S  ++   ST S +R+PP      
Sbjct: 285  SPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTS--LTKMDSTASISRTPPRASITR 342

Query: 778  YPRELS--NSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRD 835
             P   S     ST  P G    +P +    G    +SL   S       T  +       
Sbjct: 343  TPSRASPTGKPSTASPTG----TPSRASPTGSPSTASLTGLSSTASPTGTPPRASP---- 394

Query: 836  FEYSGPPPSAMMNLEKKPAK----------SILKSSKLSDTTEYQPILSSYSHRAQEFGV 885
               +G P +A  +L +KP +          SI K    +  T   P       RA   G 
Sbjct: 395  ---TGTPSTA--SLTRKPPRASPTGMLSRTSITKMDSTASPTRTPP-------RASPTGT 442

Query: 886  KSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHN 945
                 P+      S       +S  G     S  G+   +  + SPS+     TP     
Sbjct: 443  PPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASL 502

Query: 946  SLSQSTTGHLSLPQKQYPD------SPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKV--- 996
            +  +ST      P +  P       SP   P  +L     + AA T  P  + + +    
Sbjct: 503  TKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSR 562

Query: 997  -------LASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSL 1049
                    AS   T ST+    M  +AS  P+        PS+ +P+   S + LT+   
Sbjct: 563  ASLTTPSRASLTRTPSTVLLTRMPPSAS--PTG------MPSRTSPTGMPSSALLTKMDS 614

Query: 1050 TATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAP 1084
            TA+  +        ET   +S    P      G P
Sbjct: 615  TASITRTPPRASPTETPPRASPTGTPPRASPTGTP 649



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 92/364 (25%), Positives = 127/364 (34%), Gaps = 58/364 (15%)

Query: 319 SPVPSPSMDAP-------SPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDM 371
           SP   PS  +P       SPTGS S     G   + SPT       TP   +        
Sbjct: 348 SPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPT------GTPPRASPTGTPSTA 401

Query: 372 ELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSC-TPVPVTMTATPPLP 430
            L+                KP   S       T  T+  S AS   TP   + T TPP  
Sbjct: 402 SLT---------------RKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRA 446

Query: 431 KPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLT 490
            P  T    SP               +   S+ +     +  SP   PS  +PT   +  
Sbjct: 447 SPTGTPSRASP---------------TGTQSTASPTGSPSTASPTGSPSTASPTGSPSRA 491

Query: 491 SGLKTPAPATTTSHNPLANIL-SKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGN 549
           S  +TP+ A+ T     A+I  +    +P    S  S T + S     G S    ++T  
Sbjct: 492 SLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMG-SPSRAALTRT 550

Query: 550 PVPA------SEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSS 603
           P  A      S A+  + S +    T ST+    +P SA P    S        +S + +
Sbjct: 551 PSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLT 610

Query: 604 TSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESES 663
              S ASI ++P   S T   P  S        T P A PT  T  ++S    P   S +
Sbjct: 611 KMDSTASITRTPPRASPTETPPRAS-----PTGTPPRASPTG-TPPRASPTGTPPRASPT 664

Query: 664 TSPS 667
            +PS
Sbjct: 665 GTPS 668



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 151/684 (22%), Positives = 240/684 (35%), Gaps = 112/684 (16%)

Query: 699  APSESHPSDFQRGPTST-SIDNIDGTPVRDERSGTPTQDEMMDKPTSSSV---------- 747
            AP    PS  +  PT T S  ++ GTP R   +GTP+   +M  P+ +S+          
Sbjct: 2    APPTRTPS--RASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLK 59

Query: 748  DTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGM 807
             T S+ S ++SP  +              S  R  S+S+ T  P    S +  K+     
Sbjct: 60   GTTSMASLMVSPSRA--------------SLTRMQSSSLLTRTP----SMASLKRMPPRA 101

Query: 808  ERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDT- 866
             R  +L  +S  +  P T+       R    +  P  A +++    A ++   S+ S T 
Sbjct: 102  SRTRTLPRASLMR-RPSTASLTRSPSR-ASLTTTPSRASLSMTPSTAAALTMPSRASLTR 159

Query: 867  ---------TEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFS 917
                     T     L+    RA   G+ S   P+      S    D  +S        S
Sbjct: 160  TPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRAS 219

Query: 918  VRGNEPGSDRSPSPSKNDSFFTPDS----------------NHNSLSQ--STTGHLSLPQ 959
              G  P +  + SP +      P +                +  SL++  ST      P 
Sbjct: 220  PTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPS 279

Query: 960  KQYPDSPHPVPHRSLFSPQNTL---------AAPTGHPPTSGVEKVLASTISTTSTIEFK 1010
            +    SP   P R+  S   +          A+PTG    + + K + ST S + T    
Sbjct: 280  RPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTK-MDSTASISRTPPRA 338

Query: 1011 NMLKNASR-----KPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIET 1065
            ++ +  SR     KPS     G  PS+ +P+   S ++LT  S TA+            T
Sbjct: 339  SITRTPSRASPTGKPSTASPTG-TPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGT 397

Query: 1066 RVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNR----GHGR 1121
              ++S    P     + +P   L   S +    +  P +T       G   R    G   
Sbjct: 398  PSTASLTRKP----PRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPS 453

Query: 1122 EASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSF 1181
             AS  G    + S +S    PS+AS     G   +   TG  +     R P  + S+   
Sbjct: 454  RASPTG----TQSTASPTGSPSTAS---PTGSPSTASPTGSPSRASLTRTPS-RASLTKM 505

Query: 1182 RSNSFNSTFEHHLPPSPLEHGTPFQREPVG-PSSAPPVPPKDHGGIF---SRDAPTHLPS 1237
             S +  +       P+     TP    P G PS+A  +       +    SR + T  PS
Sbjct: 506  ESTASITRTPSRASPT----WTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPS 561

Query: 1238 -VDLSNP----FTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPG------EHSSSGGSG 1286
               L+ P     T+  +       PP    +G+P  T P   P        + ++S    
Sbjct: 562  RASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRT 621

Query: 1287 VPFSTPPPPPPPVDHSGVVPFPAP 1310
             P ++P   PP    +G  P  +P
Sbjct: 622  PPRASPTETPPRASPTGTPPRASP 645


>gi|239508973 PREDICTED: similar to Mucin-3A [Homo sapiens]
          Length = 596

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 88/376 (23%), Positives = 155/376 (41%), Gaps = 32/376 (8%)

Query: 396 SAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAK 455
           S  ST V  KP   ++   S T      +A    P       +P   +   +++  D   
Sbjct: 156 SYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSVSATD--- 212

Query: 456 ISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVE 515
            ++  ++++S  + T  +P    S  T TSP+ + + LKT      TS +P+ +      
Sbjct: 213 -TTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKT----AVTSTSPITS-----S 262

Query: 516 ITPESILSALSKTQTQSAPALQGLSSLLQSV-TGNPVPASEAASQS-TSASPANTTVSTI 573
           IT  + +++++ T +Q   A   LSS  +++ +  PV ++E  +   T+ +P +T V+T 
Sbjct: 263 ITSTNTVTSMTTTASQPT-ATNTLSSPTRTILSSTPVLSTETITSGITNTTPLSTLVTT- 320

Query: 574 KGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTA 633
               LP++     P S    P S TS V+ ++   A      G  ST   LP  S   ++
Sbjct: 321 ----LPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTS---SS 373

Query: 634 THNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILS 693
              T  A  P    +  ++E+S     S ST       I++ +  +   S   +     +
Sbjct: 374 LPTTETATTPMTNLVTTTTEIS-----SHSTPSFSSSTIYSTVTSHISTSTTAITSHFTT 428

Query: 694 SLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLL 753
           S  +  P+   PS       +TS+  +  + V    S T T D     PT   + T+   
Sbjct: 429 SETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTD-FPSIPT--DISTLPTR 485

Query: 754 SKIISPGSSTPSSTRS 769
           + IIS   S  S+  S
Sbjct: 486 THIISSSPSIQSTETS 501



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 79/361 (21%), Positives = 144/361 (39%), Gaps = 45/361 (12%)

Query: 471 GVSPASRPSPG-TPTSPSNLTSG----------LKTPAPATTTSHNPLANILSKVEITPE 519
           GV   + P+PG    +P  LT+           L +P  ++ TS  P +    KVE TP 
Sbjct: 59  GVPQLASPAPGHRENAPMTLTTSPHDTLISETLLNSPV-SSNTSTTPTSKFAFKVETTPP 117

Query: 520 SILSALSKTQ---------TQSAPALQGLS----SLLQSVTGNPVPASEAASQSTSASPA 566
           ++L   + T+         T S P    ++    +   S T  PV      + +++ S  
Sbjct: 118 TVLVYSATTECVYPTSFIITISHPTSICVTTTQVAFTSSYTSTPVTQKPVTTVTSTYSMT 177

Query: 567 NTTVSTIKGRNLPSSA----QPFI---PKSFNYSPNSSTSEVSSTSASKASIGQSPG-LP 618
            T   T    + PS+      P +   P S + +  +  + +SST+ +        G + 
Sbjct: 178 TTEKGTSAMTSSPSTTTARETPIVTVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIH 237

Query: 619 STTFKLPSNSLGFTATHNTSP---AAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNF 675
           +TT   P  +   TA  +TSP   +   T      ++  S+P   +  +SP+  +     
Sbjct: 238 TTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTP 297

Query: 676 LKGNPGFSGLNLNIPILSSLGSSAP---SESHPSD---FQRGPTSTSIDNIDGTPVRDER 729
           +      +    N   LS+L ++ P   S S P+    +   PTST  D+          
Sbjct: 298 VLSTETITSGITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSM 357

Query: 730 SGTPTQDEMMDKPTSSSVDTMSLLSKIIS--PGSSTPSSTRSPPPGRDESYPRELSNSVS 787
           +GT + +  +  PTSSS+ T    +  ++    ++T  S+ S P     +    +++ +S
Sbjct: 358 TGTLSTETSL-PPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHIS 416

Query: 788 T 788
           T
Sbjct: 417 T 417



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 5/190 (2%)

Query: 389 KEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALP-- 446
           +  P  ++   TS  +  T++ +K +  T +  T++    LP P ++SL  +     P  
Sbjct: 327 RSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLP-PTSSSLPTTETATTPMT 385

Query: 447 NLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNP 506
           NL        S    S +S    + V+     S    TS    +    TP P T +S + 
Sbjct: 386 NLVTTTTEISSHSTPSFSSSTIYSTVTSHISTSTTAITSHFTTSETAVTPTPVTPSSLST 445

Query: 507 LANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTG--NPVPASEAASQSTSAS 564
                S   +TP S+ ++ S T T   P++    S L + T   +  P+ ++   S+   
Sbjct: 446 DIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVG 505

Query: 565 PANTTVSTIK 574
             + T+ST++
Sbjct: 506 TTSPTMSTVR 515



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 48/185 (25%), Positives = 82/185 (44%), Gaps = 13/185 (7%)

Query: 395 KSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPS----PALALPNLAN 450
           K A STS+    +   S   + + +P T TAT P+   V T+   S    P+ +   + +
Sbjct: 350 KIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYS 409

Query: 451 VDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSN--LTSGLKTPAPATTTSHNPLA 508
              + IS+  +++TS    T    A  P+P TP+S S    T+ L+T  P++  +   L 
Sbjct: 410 TVTSHISTSTTAITSHF--TTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLT 467

Query: 509 NILSKVEITPESILSALSKTQ-TQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPAN 567
                  I P  I +  ++T    S+P++Q  S+   S+ G   P      + T     N
Sbjct: 468 TTTDFPSI-PTDISTLPTRTHIISSSPSIQ--STETSSLVGTTSPTMSTV-RMTLRITEN 523

Query: 568 TTVST 572
           T +S+
Sbjct: 524 TPISS 528


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 198/857 (23%), Positives = 310/857 (36%), Gaps = 151/857 (17%)

Query: 315  DPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELS 374
            +P+ SP+ S SM+  +  GS +      G   +S T  S   +            D  LS
Sbjct: 107  EPKTSPITSASMETTALPGSTT----TAGLSEKSTTFYSSPRS-----------PDRTLS 151

Query: 375  DVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTM--TATPPLPKP 432
                  S +         +EKS  S S P  PT  I+   S T   V+   TA+  +P  
Sbjct: 152  PARTTSSGV---------SEKSTTSHSRP-GPTHTIAFPDSTTMPGVSQESTASHSIPGS 201

Query: 433  VNTSLSP---SPALALPNLANV-------------DLAKISSILSSLTSVMKNTG----- 471
             +T+LSP   +P+   P                  D    S +L + T V  +TG     
Sbjct: 202  TDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTT 261

Query: 472  VSPASRPS-PGTPTSPSNLTSGLKT-PAPATTTSHNPLANILSKVEITPESILSALSKTQ 529
            +SP+S  +  G PT+  +  S   T PAP+ TTS         K+  T  S  S+   T 
Sbjct: 262  LSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTS------AFVKLSTTYHSSPSSTPTTH 315

Query: 530  TQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKS 589
              ++    G S     V  +PV  +     + SA+  +   ST   R+  S+     P+S
Sbjct: 316  FSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPES 375

Query: 590  FNYSPNSSTSEV--SSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVT 647
               S +S  S     ST+ +K+S       PSTT      +L  T+ H++  +   T   
Sbjct: 376  STTSGHSEESATFHGSTTHTKSS------TPSTT-----AALAHTSYHSSLGSTETTHFR 424

Query: 648  ICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSD 707
               SS +S    ES+++  S +      L                 S  S    +S PS 
Sbjct: 425  --DSSTISGRSEESKASHSSPDAMATTVLPA--------------GSTPSVLVGDSTPSP 468

Query: 708  FQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTS-----SSVDTMSLLSKIISPGSS 762
               G   T+              G+ T+  + +K T+      S DT  L +++ S G S
Sbjct: 469  ISSGSMETT-----------ALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPARMTSSGVS 517

Query: 763  TPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQ----PSDGMERPSSLMDSSQ 818
              S+T    PG   +     +   ST  P GL  ES        P+D    P S   SS 
Sbjct: 518  EESTTSHSRPGSTHT----TAFPGSTTMP-GLSQESTASHSSPGPTDTTLSPGSTTASSL 572

Query: 819  EKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSH 878
               Y  T+F       +        +A   LE   A + + SS  S  T   P  +  + 
Sbjct: 573  GPEY--TTFHSSPGSTETTLLPDNTTASGLLE---ASTPVHSSTRSPHTTLSP--AGSTT 625

Query: 879  RAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFF 938
            R  E     ++P S           D   + P    AF     EP +    SPS      
Sbjct: 626  RQGESTTFHSWPSSK----------DTRPAPPTTTSAFV----EPSTTSHGSPS------ 665

Query: 939  TPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPT---SGVEK 995
            +  + H S ++STT  L      Y  SP     +++  P++   +  G   T   S    
Sbjct: 666  SIPTTHIS-ARSTTSGLVEESTTYHSSPGST--QTMHFPESDTTSGRGEESTTSHSSTTH 722

Query: 996  VLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPS-----LT 1050
             ++S  STTS +  +    ++S   +   HF  + +    S+  + S+ +Q +     L 
Sbjct: 723  TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 782

Query: 1051 ATDQQQQEEHYRIETRVSSSCLD---LPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVE 1107
            A             + +SS  ++   LP ST   G    +  +HS+     +     +  
Sbjct: 783  ARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 842

Query: 1108 SIRVPGKGNRGHGREAS 1124
            S  V  +    H R  S
Sbjct: 843  SSGVSEESTTSHSRPGS 859



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 166/789 (21%), Positives = 273/789 (34%), Gaps = 141/789 (17%)

Query: 464  TSVMKNTGVSPASRPSPGTP-TSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESIL 522
            TS+  NT  + AS PS   P T+ S+    +     +T T H   ++  S          
Sbjct: 27   TSIGGNT--TSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSH 84

Query: 523  SALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSA 582
            S    T T   P+    S  +     +P+ +   AS  T+A P +TT + +  ++    +
Sbjct: 85   SGPGATGTTLFPSHSATSVFVGEPKTSPITS---ASMETTALPGSTTTAGLSEKSTTFYS 141

Query: 583  QPFIPKSFNYSP----NSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTS 638
             P  P     SP    +S  SE S+TS S+     +   P +T  +P  S   TA+H+  
Sbjct: 142  SPRSPDR-TLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDST-TMPGVSQESTASHSI- 198

Query: 639  PAAPPTEVTICQSSEVSKPKLESEST----SPSLEMKIHNFLKGNPGFSGL-NLNIPILS 693
               P +  T       +   L  EST    SP         L  N   SGL   + P+ S
Sbjct: 199  ---PGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR--LPDNTTTSGLLEASTPVHS 253

Query: 694  SLGS---------SAPSESHPSDFQRGPTSTSIDNI-DGTPVRDERSGTPTQDEMMDKPT 743
            S GS         S   E  P+ FQ  P+S        GT     +  T         PT
Sbjct: 254  STGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPT 313

Query: 744  S--SSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYK 801
            +  S+  T    S+  +P  S+P +T + PP    +    +  S + +R  G        
Sbjct: 314  THFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPG-------- 365

Query: 802  QPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPP-------PSAMMNLEKKPA 854
                          S+Q   +P++S           + G         PS    L     
Sbjct: 366  --------------STQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSY 411

Query: 855  KSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRL---SSSPG 911
             S L S+   +TT ++   S+ S R++E     + P ++   +  + +   +    S+P 
Sbjct: 412  HSSLGST---ETTHFRDS-STISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPS 467

Query: 912  LFGAFSVRGNE-PGSDRSPSPSKNDSFF-----TPDSNH--------NSLSQSTTGHL-- 955
               + S+     PGS   P  S+  + F     +PD+ H            +STT H   
Sbjct: 468  PISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPARMTSSGVSEESTTSHSRP 527

Query: 956  ---------------SLPQKQYPDSPHPVPHRSLFSPQNTLAAPTG-------HPPTSGV 993
                            L Q+       P P  +  SP +T A+  G         P S  
Sbjct: 528  GSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSSPGSTE 587

Query: 994  EKVLASTISTTSTIEFKNMLKNASRKP---------------SDDKHFGQAPSKGTPSDG 1038
              +L    + +  +E    + +++R P               S   H   +     P+  
Sbjct: 588  TTLLPDNTTASGLLEASTPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPP 647

Query: 1039 VSLSNLTQPSLTATDQQQQEEHYRIETRVSSS-----------------CLDLPDSTEEK 1081
             + S   +PS T+           I  R ++S                  +  P+S    
Sbjct: 648  TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 707

Query: 1082 GAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNG 1141
            G   E+   HS++   +S  P  T   +  P   +   G  A+       +TSG S ++ 
Sbjct: 708  GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 767

Query: 1142 PSSASELAS 1150
             S +S+ A+
Sbjct: 768  ASHSSQDAT 776



 Score = 35.4 bits (80), Expect = 0.41
 Identities = 82/409 (20%), Positives = 140/409 (34%), Gaps = 68/409 (16%)

Query: 907  SSSPGLFGAFSVRGNEPGS-DRSPSP-SKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYP- 963
            ++ PG+    +   + PGS D + SP +   S   P+S     S   T    LP      
Sbjct: 183  TTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTS 242

Query: 964  ---DSPHPVPHRSLFSPQNTLAAPT-----GHPPT----SGVEKVLASTISTTSTIEFKN 1011
               ++  PV H S  SP  TL+  +     G P T       +    +   TTS     +
Sbjct: 243  GLLEASTPV-HSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLS 301

Query: 1012 MLKNASRKPSDDKHFGQAPS------KGTP--SDGVSLSNLTQPSLTATDQQQQEEHYRI 1063
               ++S   +   HF  + +      + TP  S  V+ +    P+ +AT    +E     
Sbjct: 302  TTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYH 361

Query: 1064 ETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVP-----GKGNRG 1118
             +  S+  +  P+S+   G   E+  +H ++    S  P  T            G     
Sbjct: 362  RSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETT 421

Query: 1119 HGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESV 1178
            H R++S +     S    +  + P + +      G     L G  T              
Sbjct: 422  HFRDSSTIS--GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDST-------------- 465

Query: 1179 GSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAP--THLP 1236
                             PSP+  G+       G ++ P +  K      S  +P  THLP
Sbjct: 466  -----------------PSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLP 508

Query: 1237 SVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGS 1285
            +   S+  ++E+  +H+     PG      FP     P   + S++  S
Sbjct: 509  ARMTSSGVSEESTTSHSR----PGSTHTTAFPGSTTMPGLSQESTASHS 553


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.126    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,324,501
Number of Sequences: 37866
Number of extensions: 4731644
Number of successful extensions: 59947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 516
Number of HSP's successfully gapped in prelim test: 1872
Number of HSP's that attempted gapping in prelim test: 26831
Number of HSP's gapped (non-prelim): 18353
length of query: 1461
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1346
effective length of database: 13,892,928
effective search space: 18699881088
effective search space used: 18699881088
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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