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Search of human proteins with 182507165
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|182507165 thymus expressed gene 3-like [Homo sapiens]
(629 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 1266 0.0
gi|118498364 dapper 1 isoform 2 [Homo sapiens] 124 3e-28
gi|24158478 dapper 1 isoform 1 [Homo sapiens] 124 3e-28
gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo... 84 5e-16
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 82 2e-15
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 75 2e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 73 7e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 72 2e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 3e-12
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 71 3e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni... 70 8e-12
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 69 1e-11
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 67 6e-11
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 67 6e-11
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 67 6e-11
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 66 8e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 66 1e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens] 65 1e-10
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 65 2e-10
gi|48762934 alpha 2 type I collagen [Homo sapiens] 65 2e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 64 3e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 63 9e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 63 9e-10
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 63 9e-10
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 63 9e-10
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 62 1e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 62 2e-09
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 62 2e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 61 3e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 61 3e-09
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 1266 bits (3276), Expect = 0.0
Identities = 629/629 (100%), Positives = 629/629 (100%)
Query: 1 MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDE 60
MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDE
Sbjct: 1 MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDE 60
Query: 61 EDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQESGRSSGFYED 120
EDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQESGRSSGFYED
Sbjct: 61 EDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQESGRSSGFYED 120
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR
Sbjct: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
Query: 181 AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSP 240
AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSP
Sbjct: 181 AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSP 240
Query: 241 DAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSAR 300
DAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSAR
Sbjct: 241 DAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSAR 300
Query: 301 PAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYI 360
PAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYI
Sbjct: 301 PAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYI 360
Query: 361 PGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARK 420
PGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARK
Sbjct: 361 PGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARK 420
Query: 421 ASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA 480
ASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA
Sbjct: 421 ASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA 480
Query: 481 EIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGG 540
EIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGG
Sbjct: 481 EIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGG 540
Query: 541 VGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAK 600
VGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAK
Sbjct: 541 VGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAK 600
Query: 601 VFVKIKASHALKKKILRFRSGSLKVMTTV 629
VFVKIKASHALKKKILRFRSGSLKVMTTV
Sbjct: 601 VFVKIKASHALKKKILRFRSGSLKVMTTV 629
>gi|118498364 dapper 1 isoform 2 [Homo sapiens]
Length = 799
Score = 124 bits (310), Expect = 3e-28
Identities = 164/579 (28%), Positives = 220/579 (37%), Gaps = 82/579 (14%)
Query: 93 LGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGP- 151
LG D+ GG E ++ ++ PSS P S+ D G+ S + P
Sbjct: 261 LGNHASDIC---GGSELDAVKTDSSLPSPSSLWSASHPSSSKKMD-GYILSLVQKKTHPV 316
Query: 152 --SEPRGIYASERPKSL---GDASPSAPEVV--GARAAVPRSFSAPYPTAG------GSA 198
++PR ++ K L G AP V G + S A P+ G G+
Sbjct: 317 RTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTF 376
Query: 199 GPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLR 258
P S E +A A + R P P G P +G D L +
Sbjct: 377 SPPKQWSKESKAE----------QAESKRVPLPEGCP---------SGAASDLQSKHLPK 417
Query: 259 RRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERV-------- 310
+ R S G P+ + P SPS G A P ++ +
Sbjct: 418 TAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNS 477
Query: 311 --GGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATR 368
G P +P LS A+ PA + S E LVKAQ+IPG Q + R
Sbjct: 478 LQGVPPATPPLLSTAFP------VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVR 531
Query: 369 --------GLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARK 420
G+ ++ + P +G RE+ RA ++ R + + + +K
Sbjct: 532 LHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDT--NKKLKK 589
Query: 421 ASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA 480
AS S+ S G + VP P R R R RRW+S+A
Sbjct: 590 AS-SKGRKSGGGPEAGVPGRPAG--GGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSA 646
Query: 481 EIDAADGRRVRPRAPAARV---PGPGPSPSAPQRRLLYGCAGSDSECSA-------GRLG 530
EI + R R V P P P P A Y SDSE SA +
Sbjct: 647 EISYEEALRRARRGRRENVGLYPAPVPLPYASP----YAYVASDSEYSAECESLFHSTVV 702
Query: 531 PLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGA 590
+ +G+SESS SEGE S+ +SDS+ SGGL+W Q T
Sbjct: 703 DTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLIWSQ--FVQTLPIQTVT 760
Query: 591 GAGAPAGPAKVFVKIKASHALKKKILRFRSGSLKVMTTV 629
PAK FVKIKASH LKKKILRFRSGSLK+MTTV
Sbjct: 761 APDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 799
Score = 60.1 bits (144), Expect = 6e-09
Identities = 121/509 (23%), Positives = 175/509 (34%), Gaps = 115/509 (22%)
Query: 12 ERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGA------------EAED 59
ER R R E +LAGL EL +LR+RQE V+ ALR G GGA EA
Sbjct: 40 ERQRTRERQEATLAGLAELEYLRQRQELLVRGALR----GAGGAGAAAPRAGELLGEAAQ 95
Query: 60 EEDADE---DEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLE-----SGGLEQES 111
+E +E+ R+ L + L + +L +Q+ DL L+ LE +S
Sbjct: 96 RSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDS 155
Query: 112 GRSSGFYE--DPSSTGGPDSPPSTF--CGDSGFSGSSSYGRLGPSEPRGIYASERPKSLG 167
SSGFYE D +S +S S F C S S + L E SL
Sbjct: 156 RPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPL-----------EATLSLS 204
Query: 168 DASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMR 227
D P + +V P+ + + PSPLHAVA++
Sbjct: 205 DGCPKSADV----------------------NPKYQCDLVSKNGNDVYRYPSPLHAVAVQ 242
Query: 228 SPR----------------------PCGRPPTD---------------SPDAGGAGRPLD 250
SP CG D S + + +D
Sbjct: 243 SPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMD 302
Query: 251 GYISALLRRRRRR-GAGQPRTSPGG-ADGGPRRQNSVRQRPPDASPSPGSA--RPAREPS 306
GYI +L++++ +PRTS G R SV R P S + +++
Sbjct: 303 GYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQAC 362
Query: 307 LERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAA 366
L G + S W E+ E A P P P+ A +
Sbjct: 363 LPSGGIPSLNNGTFSP--PKQWSKESKAEQAESKRVPLPEGCPSGA----ASDLQSKHLP 416
Query: 367 TRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQS 426
P + + G S P+E + +G + + + G P+ K +
Sbjct: 417 KTAKPASQEHARCSAIGTGES-----PKESAQLSGASPKESPSRG-PAPPQENKVVQPLK 470
Query: 427 ETSLLGRASAV-PSGPPKYPTAEREEPRP 454
+ S V P+ PP TA E RP
Sbjct: 471 KMSQKNSLQGVPPATPPLLSTAFPVEERP 499
>gi|24158478 dapper 1 isoform 1 [Homo sapiens]
Length = 836
Score = 124 bits (310), Expect = 3e-28
Identities = 164/579 (28%), Positives = 220/579 (37%), Gaps = 82/579 (14%)
Query: 93 LGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGP- 151
LG D+ GG E ++ ++ PSS P S+ D G+ S + P
Sbjct: 298 LGNHASDIC---GGSELDAVKTDSSLPSPSSLWSASHPSSSKKMD-GYILSLVQKKTHPV 353
Query: 152 --SEPRGIYASERPKSL---GDASPSAPEVV--GARAAVPRSFSAPYPTAG------GSA 198
++PR ++ K L G AP V G + S A P+ G G+
Sbjct: 354 RTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTF 413
Query: 199 GPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLR 258
P S E +A A + R P P G P +G D L +
Sbjct: 414 SPPKQWSKESKAE----------QAESKRVPLPEGCP---------SGAASDLQSKHLPK 454
Query: 259 RRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERV-------- 310
+ R S G P+ + P SPS G A P ++ +
Sbjct: 455 TAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNS 514
Query: 311 --GGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATR 368
G P +P LS A+ PA + S E LVKAQ+IPG Q + R
Sbjct: 515 LQGVPPATPPLLSTAFP------VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVR 568
Query: 369 --------GLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARK 420
G+ ++ + P +G RE+ RA ++ R + + + +K
Sbjct: 569 LHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDT--NKKLKK 626
Query: 421 ASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA 480
AS S+ S G + VP P R R R RRW+S+A
Sbjct: 627 AS-SKGRKSGGGPEAGVPGRPAG--GGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSA 683
Query: 481 EIDAADGRRVRPRAPAARV---PGPGPSPSAPQRRLLYGCAGSDSECSA-------GRLG 530
EI + R R V P P P P A Y SDSE SA +
Sbjct: 684 EISYEEALRRARRGRRENVGLYPAPVPLPYASP----YAYVASDSEYSAECESLFHSTVV 739
Query: 531 PLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGA 590
+ +G+SESS SEGE S+ +SDS+ SGGL+W Q T
Sbjct: 740 DTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLIWSQ--FVQTLPIQTVT 797
Query: 591 GAGAPAGPAKVFVKIKASHALKKKILRFRSGSLKVMTTV 629
PAK FVKIKASH LKKKILRFRSGSLK+MTTV
Sbjct: 798 APDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
Score = 68.6 bits (166), Expect = 2e-11
Identities = 128/524 (24%), Positives = 185/524 (35%), Gaps = 108/524 (20%)
Query: 12 ERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGA------------EAED 59
ER R R E +LAGL EL +LR+RQE V+ ALR G GGA EA
Sbjct: 40 ERQRTRERQEATLAGLAELEYLRQRQELLVRGALR----GAGGAGAAAPRAGELLGEAAQ 95
Query: 60 EEDADE---DEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLE-----SGGLEQES 111
+E +E+ R+ L + L + +L +Q+ DL L+ LE +S
Sbjct: 96 RSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDS 155
Query: 112 GRSSGFYE--DPSSTGGPDSPPSTF--CGDSGFSGSSSYGRLGPSEPRGIYASERPKSLG 167
SSGFYE D +S +S S F C S S + L E SL
Sbjct: 156 RPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPL-----------EATLSLS 204
Query: 168 DASPSAPEVVG------------ARAAVPRSFSAPYPTA---GGSAGPEACSSAERRARA 212
D P + +++G A AV RS S P + P+ +
Sbjct: 205 DGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQFNSLDVIADVNPKYQCDLVSKNGN 264
Query: 213 GPFLTPSPLHAVAMRSPR----------------------PCGRPPTD------------ 238
+ PSPLHAVA++SP CG D
Sbjct: 265 DVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPS 324
Query: 239 ---SPDAGGAGRPLDGYISALLRRRRRR-GAGQPRTSPGG-ADGGPRRQNSVRQRPPDAS 293
S + + +DGYI +L++++ +PRTS G R SV R P
Sbjct: 325 SLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGV 384
Query: 294 PSPGSA--RPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAE 351
S + +++ L G + S W E+ E A P P P+
Sbjct: 385 SQGNSVNLKNSKQACLPSGGIPSLNNGTFSP--PKQWSKESKAEQAESKRVPLPEGCPSG 442
Query: 352 GRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASG 411
A + P + + G S P+E + +G + + + G
Sbjct: 443 A----ASDLQSKHLPKTAKPASQEHARCSAIGTGES-----PKESAQLSGASPKESPSRG 493
Query: 412 RRGSPRARKASRSQSETSLLGRASAV-PSGPPKYPTAEREEPRP 454
P+ K + + S V P+ PP TA E RP
Sbjct: 494 -PAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERP 536
>gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo
sapiens]
Length = 774
Score = 83.6 bits (205), Expect = 5e-16
Identities = 205/794 (25%), Positives = 270/794 (34%), Gaps = 209/794 (26%)
Query: 12 ERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAA 71
+R RL L + AGL EL LR Q+ RV+ AL L P A ++ A
Sbjct: 14 DRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPEQQLEA 73
Query: 72 ARRAAAALEEQLEALP----GLVWDLGQ---QLGDLSLESG-----GLEQESGRSSGFYE 119
A AAL+EQL L GL L Q Q+ L L+ G L+ +S SSGFYE
Sbjct: 74 A---LAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSDSRPSSGFYE 130
Query: 120 DPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGP----SEPRGIYASERPKSLGDAS----- 170
S GG S ++ S S G L P + R RP+S+ + +
Sbjct: 131 --MSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDETTVPAWR 188
Query: 171 PSAPEVVGAR-------AAVPRSFSAPYPTAGGSAG---------PEACSSAE------- 207
P A E GAR A P P P + G +A + AE
Sbjct: 189 PQATEE-GARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQ 247
Query: 208 ------------------RRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPL 249
+ + PSPLHAVA++SP T P GG P
Sbjct: 248 GVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKET--PQRGGPSFPR 305
Query: 250 DGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSV---------RQRPPDASPSP-GSA 299
+ R G +T P + GP R + R+ P S G
Sbjct: 306 ES-------PRGPAGLNTIQTGPV-LEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357
Query: 300 RPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE--------------------PAAP 339
R A PS +R GG T +A E E P P
Sbjct: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQS 417
Query: 340 PAAPSPPDSPAEGRLV-----------KAQYIPGAQAATRG---LPGRAARRKP------ 379
+ P P+ ++ KAQ P AQ RG P R + P
Sbjct: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477
Query: 380 -------------PPLTRGRSVEQSPPRERPRAAGR------RGRMAEASGR-------- 412
PP ++ +++SP + R A + R A A+ +
Sbjct: 478 FAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPA 537
Query: 413 -----RGSPRARKA------SRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGP 461
RG + R A RS SE++L VP A +E R P
Sbjct: 538 HWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLA-----VAPQESHRTSAQALFP 592
Query: 462 --APTLAAQAAGSCRRWRSTAEIDA------ADGRRVRPRAPAARVPGPGPSPSAPQRRL 513
A L + A RRW+ST EI A + P P AR G + P
Sbjct: 593 FEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVR 652
Query: 514 LYGCAGSDSECSAGRLG---------PLGRRGPAGG-VGGGYGESESSASEGESPAFSSA 563
SDSE S P G + +G+ ESS+S+ E A
Sbjct: 653 QDAYTRSDSEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGA---Q 709
Query: 564 SSDSD--------GSGGLVWPQQLVAATAASGGGAGAGAPAGPAKVFVKIKASHALKKKI 615
S D D G L W Q+ ++ G P +IKAS ALKKKI
Sbjct: 710 SRDCDLALGYVAAGHAELAWTQEAPVSS---------GPLLSPVPKLCRIKASKALKKKI 760
Query: 616 LRFRSGSLKVMTTV 629
RF+ +LKVMT V
Sbjct: 761 RRFQPTALKVMTMV 774
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 81.6 bits (200), Expect = 2e-15
Identities = 152/565 (26%), Positives = 189/565 (33%), Gaps = 93/565 (16%)
Query: 106 GLEQESGRS-----SGFYEDPSSTGGPDSP-PSTFCGDSGFSGS-SSYGRLGPSEPRGIY 158
GL E GR +G + +TG P P+ G GF G+ + G GP PRG
Sbjct: 305 GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG-- 362
Query: 159 ASERPKSL-GDASPSAPEVVGARAAVPRSFSAP----------------YPTAGGSAGPE 201
SE P+ + G+ P P A P + P +P A G +GP+
Sbjct: 363 -SEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ 421
Query: 202 ACSSAER-RARAG-PFLTPSPLHAVAMRSPRPCG--RPPTDSPDAGGAGRPLDGYISALL 257
+ +G P S A P P G PP + + G G + + L
Sbjct: 422 GPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP 481
Query: 258 RRRRRRGAGQPRTSPGGADG--GPRRQNSVRQRPPDASP--SPGSA-RPARE--PSLERV 310
RG R PG ADG GP+ R P A P SPG A RP P + +
Sbjct: 482 GPPGERGGPGSRGFPG-ADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL 540
Query: 311 GGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGL 370
G P SP + P PA P PP P PG + A G
Sbjct: 541 TGSPGSPGPDGKT--------GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA-GE 591
Query: 371 PGRAARRKPP-------PLTR-GRSVEQSPPRERPRAAGRRGRMAEAS--------GRRG 414
PG+A R P P + G + Q PP AG RG A G G
Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG-PAGERGEQGPAGSPGFQGLPGPAG 650
Query: 415 SPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCR 474
P Q LG + + ER PP GPA A A
Sbjct: 651 PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP----GPAGPRGANGAPGND 706
Query: 475 RWRSTAEIDAADGRRVRP-------RAPAARVPGP-------GP-----SPSAPQRRLLY 515
+ A A G + P AA +PGP GP SP R L
Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766
Query: 516 GCAGSDSECSA-GRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLV 574
G G A G G G GPAG G + PA + +DG G
Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG-- 824
Query: 575 WPQQLVAATAASGGGAGAGAPAGPA 599
+ A + G AG PAGPA
Sbjct: 825 --AKGEPGDAGAKGDAGPPGPAGPA 847
Score = 77.4 bits (189), Expect = 4e-14
Identities = 146/522 (27%), Positives = 176/522 (33%), Gaps = 89/522 (17%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSY-GRLGPSEPRGIY-ASERPKSLGDA-SPSAPEVV 177
P G P PS G+ GF G G GP+ PRG A + GDA +P AP
Sbjct: 664 PGDLGAPG--PSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721
Query: 178 GARA--AVPRSFSA---PYPTAG-GSAGPEACSSAER----RARAGPFLTPSPLHAVAMR 227
GA +P A P P G AGP+ + R GP P P A +
Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK 781
Query: 228 SPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPR--TSPGGADGGPRRQNSV 285
P + G G P D R G P P GADG P
Sbjct: 782 GE---SGPSGPAGPTGARGAPGD---------RGEPGPPGPAGFAGPPGADGQP----GA 825
Query: 286 RQRPPDASPS-----PGSARPAREPS-LERVG--------GHPTSPAALSRAWASSWESE 331
+ P DA PG A PA P + VG G P A A+
Sbjct: 826 KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885
Query: 332 AAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQS 391
P A P P P G+ + + P + G PG P P S
Sbjct: 886 PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG-----PPGPAGEKGSPGAD 940
Query: 392 PPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPP--KYPTAER 449
P P G +G +G+RG + L G PSG P + P+
Sbjct: 941 GPAGAPGTPGPQG----IAGQRGVVGLPGQRGERGFPGLPG-----PSGEPGKQGPSGAS 991
Query: 450 EEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAAR----VPGPGPS 505
E PP P GP P LA S R AE + GR P A R GP +
Sbjct: 992 GERGPPGPM-GP-PGLAGPPGESGREGAPGAE--GSPGRDGSPGAKGDRGETGPAGPPGA 1047
Query: 506 PSAPQRRLLYGCAGSDSECS-------AGRLGPLGRRGPAG--GVGGGYGESESSASEGE 556
P AP G AG + AG +GP+G RGPAG G G GE+ G
Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRG- 1106
Query: 557 SPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGP 598
G GL P + G +GA PAGP
Sbjct: 1107 -------IKGHRGFSGLQGPPG-PPGSPGEQGPSGASGPAGP 1140
Score = 72.0 bits (175), Expect = 2e-12
Identities = 146/600 (24%), Positives = 181/600 (30%), Gaps = 153/600 (25%)
Query: 106 GLEQESGRSSGFYEDPSSTGGPDSP--PSTFCGDSGFSGSSSYGRLGPSEPRGIYASERP 163
G E + + + E P GP P P+ G G G G GP P G
Sbjct: 98 GSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQP--GLPGPPGPPG------- 148
Query: 164 KSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPL-- 221
P P +G A S+ + GG + P + R GP P P
Sbjct: 149 -------PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201
Query: 222 ----------HAVAMRSPRPCGRPPTDSPDAGGAGRP----------------------- 248
A PR PP + D G AG+P
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261
Query: 249 --LDGY--ISALLRRRRRRGAGQPRTSPG-----GADG--GPRRQNSVRQRPPDASPSPG 297
+ G+ S L + G P+ PG GA G GPR R RP +P P
Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP--GAPGPA 319
Query: 298 SAR-------PAREPSLERVGGHPTSPAALS----------RAWASSWESEAAPEPAAPP 340
AR A P G P P A+ R P P P
Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379
Query: 341 AAPSPPDSP-AEGRLVKAQYIPGAQAAT-----RGLPGRAARRKP--------PPLTRGR 386
A P +P A+G+ PGA+ A G PG R P PP +G
Sbjct: 380 GAAGPAGNPGADGQ-------PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN 432
Query: 387 SVEQSPPRER-----------------PRAAGRRGRMAE-----ASGRRGSPRARKASRS 424
S E P + P AG G+ +G G P R S
Sbjct: 433 SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492
Query: 425 QSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAG--SCRRWRSTAEI 482
+ G A PK P ER P P P+ P AG + +
Sbjct: 493 RGFPGADGVAG------PKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGS 546
Query: 483 DAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSA----GRLGPLGRRGPA 538
DG + P PA + PGP P P R G G A G+ G G GP
Sbjct: 547 PGPDG-KTGPPGPAGQDGRPGP-PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604
Query: 539 GGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGP 598
G VG + E+ A PA + G G S G G PAGP
Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAG-------------SPGFQGLPGPAGP 651
Score = 71.2 bits (173), Expect = 3e-12
Identities = 151/581 (25%), Positives = 180/581 (30%), Gaps = 129/581 (22%)
Query: 51 GMGGAEAEDEEDADEDEDAAAARRAAAAL-----EEQLEALPGLVWDLGQQLGDLSLESG 105
G GA D D A + A L E LPG D G + S
Sbjct: 698 GANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSP 757
Query: 106 GLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKS 165
G + G + P GP P GD G SG S GP+ P G A P
Sbjct: 758 GKDGVRGLTG-----PIGPPGPAGAP----GDKGESGPS-----GPAGPTG--ARGAPGD 801
Query: 166 LGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPE-------ACSSAERRARAGPFLTP 218
G+ P P F+ P P A G G + A A AGP P
Sbjct: 802 RGEPGPPGPA----------GFAGP-PGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850
Query: 219 SPLHAVAM---RSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRT-SPGG 274
P+ V + R PP + G AGR S AG P P G
Sbjct: 851 GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG--------NAGPPGPPGPAG 902
Query: 275 ADGG--PRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEA 332
+GG PR + RP + P PG PA E S
Sbjct: 903 KEGGKGPRGETGPAGRPGEVGP-PGPPGPAGEKG-----------------------SPG 938
Query: 333 APEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLT--RGRSVEQ 390
A PA P P P + +V +PG Q RG PG P G S E+
Sbjct: 939 ADGPAGAPGTPGPQGIAGQRGVVG---LPG-QRGERGFPGLPGPSGEPGKQGPSGASGER 994
Query: 391 SPPRER--PRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLG-RASAVPSGPPKYPTA 447
PP P AG G SGR G+P A + G R P+GPP P A
Sbjct: 995 GPPGPMGPPGLAGPPGE----SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050
Query: 448 EREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPS-P 506
P P A +G D + P P V GP+ P
Sbjct: 1051 PG----------APGPVGPAGKSG-----------DRGETGPAGPAGPVGPVGARGPAGP 1089
Query: 507 SAPQRRLLYGCAGSDSECS-------AGRLGPLGRRGPAGGVGGGYGESESSASEGESPA 559
P+ G G E G G G GP G G S + P
Sbjct: 1090 QGPR-----GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPP 1144
Query: 560 FSSASSDSDGSGGLVWPQQLVAATAASG--GGAGAGAPAGP 598
S+ + DG GL P + G G AG P GP
Sbjct: 1145 GSAGAPGKDGLNGLPGP---IGPPGPRGRTGDAGPVGPPGP 1182
Score = 45.1 bits (105), Expect = 2e-04
Identities = 74/276 (26%), Positives = 92/276 (33%), Gaps = 35/276 (12%)
Query: 119 EDPSSTGGPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASE-RPKSLGDASPSAPEV 176
+ PS G PP G G +G GR G G + P + GD + P
Sbjct: 985 QGPSGASGERGPPGPM-GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGP-- 1041
Query: 177 VGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPP 236
A P + AP A G GP S R GP P+ V R P P
Sbjct: 1042 ----AGPPGAPGAP--GAPGPVGPAGKSGD--RGETGPAGPAGPVGPVGARGPAGPQGPR 1093
Query: 237 TDSPDAGGAG-RPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQN-SVRQRPPDASP 294
D + G G R + G+ RG + P G G P Q S P
Sbjct: 1094 GDKGETGEQGDRGIKGH----------RGFSGLQ-GPPGPPGSPGEQGPSGASGPAGPRG 1142
Query: 295 SPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE-PAAPPAAPSPPDSPAEGR 353
PGSA + L + G P R +A P P PP P PP P+ G
Sbjct: 1143 PPGSAGAPGKDGLNGLPGPIGPPGPRGRT------GDAGPVGPPGPPGPPGPPGPPSAGF 1196
Query: 354 LVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVE 389
P + A G GR R + R R +E
Sbjct: 1197 DFSFLPQPPQEKAHDG--GRYYRADDANVVRDRDLE 1230
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 74.7 bits (182), Expect = 2e-13
Identities = 138/568 (24%), Positives = 198/568 (34%), Gaps = 139/568 (24%)
Query: 56 EAEDEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQESGRSS 115
E E+EE+ +E+ED EE+ E L Q + +S G+ ++ S
Sbjct: 271 EEEEEEEEEEEED-----------EEEEEGL-------SQSISRISETLAGIYDDNSLSQ 312
Query: 116 GFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPE 175
F D S PD+ P+ G R + R ++
Sbjct: 313 DFPGDESPR--PDAQPTQPTPAPGTPPQVDSTRADGAMRRRVF----------------- 353
Query: 176 VVGARAAVPRS--FSAPYPTAGGSA-GPEACSSAERRARAGPFLTPSPLHAVAMRSPRPC 232
VVG A R S TAGG+A P + G + P +A+ RP
Sbjct: 354 VVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPG 413
Query: 233 GRP--PTDSPDAGGAGRPL-----------DGYISALLRRRRRRGA-----GQPRTSPGG 274
GR PT + A +PL D ++S L GA G+P +P
Sbjct: 414 GRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLS-LHAESDGEGALQVDLGEPAPAPPA 472
Query: 275 AD---GG--------PRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRA 323
AD GG +R+ RQR P +P+P A A G PT +
Sbjct: 473 ADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAA---------GPPTRKKSRRER 523
Query: 324 WASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQ-YIPGAQAATRGLPGRAARRKPPPL 382
S EAA + AP P SP + + +++ PG+ A++ +ARR+
Sbjct: 524 KRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASS------SARRRSRSR 577
Query: 383 TRGRSV-EQSPPRERPRAAGRRGRMAEASGRR---------------------------- 413
+R RS +S +R R RR R E RR
Sbjct: 578 SRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDG 637
Query: 414 -GSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAP----TLAAQ 468
GS + +K SRS+ E G S P P+ RRG P L
Sbjct: 638 GGSKKKKKRSRSRGE-KRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDH 696
Query: 469 AAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSP-SAPQRRLLYGCAGSDSECSAG 527
+ +R + +D +D R GP P+P S+P+R +LY G E G
Sbjct: 697 DLFAIKRTITVGRLDKSDPR------------GPSPAPASSPKREVLYDSEGLSGEERGG 744
Query: 528 RLGPLGRRGPAGGVGGGYGESESSASEG 555
+ RR G S SS +G
Sbjct: 745 KSSQKDRRR-----SGAASSSSSSREKG 767
Score = 43.9 bits (102), Expect = 4e-04
Identities = 79/359 (22%), Positives = 126/359 (35%), Gaps = 74/359 (20%)
Query: 138 SGFSGSSSYGRLGPSEPRGIYASERPKSLG---DASPSAPEVVGARAAVPRSFSAPYPT- 193
SG + SSS R S + + +R + D S+ + + + P S P P
Sbjct: 754 SGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPV 813
Query: 194 ---AGGSAGPEACSSAERRARAGPFL---------TPSPLHAVA--------------MR 227
+G S+ +CSS + + ++ + TP+ A A R
Sbjct: 814 SSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESR 873
Query: 228 SP--RPCGRPPTDSPDAG-GAGRPLDGYISALLRRRRRRGAGQPRTSP---------GGA 275
SP +P R PT+ A G+ +P + A ++ +G + +T P GG
Sbjct: 874 SPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGT-KGKTKPSKTRKKVRSGGG 932
Query: 276 DGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE 335
GG Q S+++ D+ + A E S W S E AA
Sbjct: 933 SGGSGGQVSLKKSKADSCSQAAGTKGAEETS-----------------W--SGEERAAKV 973
Query: 336 PAAPP--AAPSPPDSPAEGRLV-------KAQYIPGAQAATRGLPGRAARRKPPPLTRGR 386
P+ PP AAP PP + + V + ++P G+ G A +
Sbjct: 974 PSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEE---EEEE 1030
Query: 387 SVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYP 445
E+ E+ A A A+ A S +E R S +P+ PP P
Sbjct: 1031 EEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLPTLPPPMP 1089
Score = 41.6 bits (96), Expect = 0.002
Identities = 102/443 (23%), Positives = 151/443 (34%), Gaps = 106/443 (23%)
Query: 162 RPKSLGDASPSAPEV-VGARAAVPRSFSAPYPT-----AGGSAGPEACSSAERRAR---- 211
RP D EV +G R +P + P G + P++ SS AR
Sbjct: 118 RPGESEDMLELVAEVRIGDRDPIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTL 177
Query: 212 ----AGPFLTPSPLHAVAMRSPRPCGR-------PPTDSPDAGGAGR--------PLDGY 252
GP P+P A + SP P PP +P A A R P D
Sbjct: 178 GTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEA 237
Query: 253 ISALLRRRRRRGAGQPR-TSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVG 311
S ++ +P ++P + G P P+ E E
Sbjct: 238 YSPPPAPEQKYDPFEPTGSNPSSSAGTP---------SPEEEEEEEEEEEEEEEDEEEEE 288
Query: 312 GHPTSPAALSRAWASSWE---------SEAAPEPAAPPAAPSP-PDSP-------AEGRL 354
G S + +S A ++ + +P P A P P+P P +P A+G +
Sbjct: 289 GLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAM 348
Query: 355 VKAQYIPGAQA--------ATRGLPGRAARRKPPPLTRGRS-VEQS---PPRERPRAA-- 400
+ ++ G +A + + A PP L G S +E+ P E PR A
Sbjct: 349 RRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALS 408
Query: 401 -----GRRGRMAEASG---------RRGSPRARKA-------SRSQSETSL---LGRASA 436
GR R A+ + +PRA + + S E +L LG +
Sbjct: 409 LFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAP 468
Query: 437 VPSGPP----------KYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAAD 486
P K T RE R P PAP AA AAG R +S E +
Sbjct: 469 APPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAA-AAGPPTRKKSRRERKRSG 527
Query: 487 GRRVRPRAPAARVPGPGPSPSAP 509
+ + + P P P+P++P
Sbjct: 528 EAKEAASSSSGTQPAP-PAPASP 549
Score = 31.6 bits (70), Expect = 2.3
Identities = 87/381 (22%), Positives = 134/381 (35%), Gaps = 46/381 (12%)
Query: 103 ESGGLEQESGRSSGFYEDPSSTGG-----PDSPPS--TFCGDSGFSGSSSYGRLGPS--- 152
+ GG +++ RS E S G P PPS T CGD S G + PS
Sbjct: 636 DGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRD---SRRRGAVPPSIQD 692
Query: 153 -EPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAER-RA 210
++A +R ++G S P A Y + G S S+++ R
Sbjct: 693 LTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRR 752
Query: 211 RAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRT 270
R+G + S R + D G R D R R + A P+
Sbjct: 753 RSGAASSSSSSREKGSRRK---------ALDGGDRDRDRDRDRD---RDRSSKKARPPKE 800
Query: 271 SPGGADGGPRRQNSVRQRPPDASPSPGSAR---PAREPSLERVGGHPTSPAALSRAWASS 327
S + P+ S +S S S + ++ L R G T+PA + AS+
Sbjct: 801 SAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPA---KDAASA 857
Query: 328 WESEAAPEPAAPPAAPSP---PDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTR 384
+ + + SP PD A + KA PG+ + A K T+
Sbjct: 858 GLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAA--PGSTKPKKTKVKAKAGAKKTKGTK 915
Query: 385 GRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKY 444
G++ + S R++ R+ G SG G + K S++ S + G A +
Sbjct: 916 GKT-KPSKTRKKVRSGG-------GSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGE 967
Query: 445 PTAEREEPRPPRPRRGPAPTL 465
A + PP P P L
Sbjct: 968 ERAAKVPSTPPPKAAPPPPAL 988
Score = 29.6 bits (65), Expect = 8.8
Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 2/55 (3%)
Query: 53 GGAEAEDEEDADEDEDAAAARR--AAAALEEQLEALPGLVWDLGQQLGDLSLESG 105
GGAE E+EE+ +E+E+ + A A P G GD E G
Sbjct: 1019 GGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDG 1073
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 73.2 bits (178), Expect = 7e-13
Identities = 132/515 (25%), Positives = 177/515 (34%), Gaps = 104/515 (20%)
Query: 151 PSEPRGIYASERPKSLGDASPSAPEVVGARA--AVPRSFSAPYPTAGGSAGP-------E 201
P P E P S+ P AP + + +P +P T A P +
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 202 ACSSAERRARAGPFLTPSPL--HAVAMR------SPRPCGRPPTDSPDAGGAGRPLDGYI 253
A S P TPSP +A+A+ SP P PP +P + A P+
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPSA 689
Query: 254 SALLRRRRRRGAGQ---PRTSPGGADGGPRRQNSVRQRPPDASP--------------SP 296
+ + A P + P P + PP A+P SP
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749
Query: 297 GSARPAREPSL---ERVGGHPTSPAALSRAWASSWESEAAPEPAAPP--AAPSPPDS-PA 350
+ P R P L + P+ PA+L + + +A P A PP A PSPP S P
Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809
Query: 351 EGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTR-GRSVEQSPPRERPRAAGRRGRMAEA 409
+ + +P + AT P +A PL + S SP + PR G
Sbjct: 810 QAPFSPSASLPMSPLATP--PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867
Query: 410 SGRRGS---------PRARKASRSQSETSLLGRASAVPSGPPKY---------------- 444
SG R + P +R S + S L G +S+ S P +
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927
Query: 445 PTAEREEPRPPRPRRGPAPTLAAQAA-GSCRRWRSTAEIDAADGR---------RVRPRA 494
P AE P RGPAP LA + A G+ W +ADG A
Sbjct: 928 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987
Query: 495 PAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLG--PLG------------------- 533
P A PGP P S + G S RLG PLG
Sbjct: 988 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA 1047
Query: 534 RRGPAGGVGGGYGESESSASEGESPAFSSASSDSD 568
G AGG GGG G +E G + A A SD++
Sbjct: 1048 AEGAAGGSGGGPGGAEGGGVTGGARA---ALSDAE 1079
Score = 59.3 bits (142), Expect = 1e-08
Identities = 92/363 (25%), Positives = 121/363 (33%), Gaps = 76/363 (20%)
Query: 163 PKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLH 222
P+ +P+A V+GA AV R P A + G + E RAGP
Sbjct: 33 PRPPPPVTPAALRVLGAAGAVGRK-----PLAERAGGIGGATIPESAPRAGP-------- 79
Query: 223 AVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQ 282
RS R P P A G G R TSPG R
Sbjct: 80 ---TRSAGTSSRNPASRPPASGRGE---------------RAPPAKNTSPGPVSSPGRAS 121
Query: 283 NSVRQRPPDASPSPGSARPAREPSLERVG-GHPTSPAALSRAWASSWESEAAPEPAAPPA 341
+ R P P + R + E V G T S A + + P P P
Sbjct: 122 GTTR-------PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-- 172
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRG--RSVEQSPPRERPRA 399
SPA R +A G + GLP A +P P T G +SV +
Sbjct: 173 ------SPAMARRSRAA---GTEV---GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
Query: 400 AGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEP------- 452
+ R A G P +R S S + S R+ G P+ P A +P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP-AHPSQPKPKGLQA 279
Query: 453 -RPPR---PRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPA--ARVPGPGPSP 506
RPP+ PR+ AP L ++ S + G + RP P A P P P
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSS-------SPLATPSPSGTKARPVPPPDNAATPLPATLP 332
Query: 507 SAP 509
+P
Sbjct: 333 PSP 335
Score = 51.6 bits (122), Expect = 2e-06
Identities = 83/335 (24%), Positives = 105/335 (31%), Gaps = 36/335 (10%)
Query: 136 GDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAG 195
G G + S R GP+ G +S P S AS A+ P S+P A
Sbjct: 64 GIGGATIPESAPRAGPTRSAGT-SSRNPASRPPASGRGERAPPAKNTSPGPVSSP-GRAS 121
Query: 196 GSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISA 255
G+ P R A + RS G S G P A
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP------A 175
Query: 256 LLRRRRRRGA--GQPRTSPGGADG----GPRRQNSVRQRPPDASPSPGSAR-PAREPSLE 308
+ RR R G G PR +P GPR+ S PSP + R P+ L+
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 309 RVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATR 368
R P S + S A S + + P P AP+ P P P A R
Sbjct: 236 R----PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK----------PKGLQALR 281
Query: 369 GLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSET 428
R+ P S S P P +G + R +P S
Sbjct: 282 PPQVTPPRKDAAPALGPLS---SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
Query: 429 SLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAP 463
+ L A PS PP T P PP AP
Sbjct: 339 TPLPLAPPSPSAPPSLQTL----PSPPATPPSQAP 369
Score = 40.8 bits (94), Expect = 0.004
Identities = 91/390 (23%), Positives = 128/390 (32%), Gaps = 89/390 (22%)
Query: 132 STFCGDSGFSGSSSYGRLGPSEPRGIYAS-ERPKSLGDASPSAPEVVGARAAVPRSFSAP 190
+T G + S+ + P + + S RP S SP + A+ P S
Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
Query: 191 YPTAGGSAGP------EACSSAERRARAGPF--LTPSPLHAVAMRSPRPCGRPPTDSPDA 242
P + P +A SS + P L PL + +P P +P A
Sbjct: 475 -PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP-----PSLQTPPA 528
Query: 243 GGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPA 302
PL+ S L + A P T+P + PP +P P A P+
Sbjct: 529 SLTTPPLENLPS--LAPPPLQTASAPLTTPH------------LETPPCPAPCPLQAPPS 574
Query: 303 REPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPG 362
+ P +P+++ A P P APPA SPP
Sbjct: 575 PLTTPP-----PETPSSI-----------ATPPPQAPPALASPP---------------- 602
Query: 363 AQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKAS 422
+GLP PPL S +PP + P A S P + A+
Sbjct: 603 ----LQGLPS-------PPL----SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647
Query: 423 RS-QSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAE 481
S Q+ +L P PP P + P P P+ T +QA S
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL-------- 699
Query: 482 IDAADGRRVRPRAPAA--RVPGPGPSPSAP 509
AA +V P PA+ P P P AP
Sbjct: 700 --AAPPLQVPPSPPASPPMSPSATPPPQAP 727
Score = 38.9 bits (89), Expect = 0.014
Identities = 76/281 (27%), Positives = 94/281 (33%), Gaps = 48/281 (17%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
PS+ GG P S S + SS R GPS A P++ A PS P+ G +
Sbjct: 228 PSAGGGLQRPASRSLSSSA-TPLSSPARSGPS------ARGTPRA--PAHPSQPKPKGLQ 278
Query: 181 AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRP---PT 237
A P + P A + GP + S P TPSP A P P P
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSS---------PLATPSPSGTKARPVPPPDNAATPLPA 329
Query: 238 DSPDAGGAGRPLD-GYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSP 296
P + PL S + P T P A P Q PP P
Sbjct: 330 TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP--PSMTTPPMQAPPSLQTIP 387
Query: 297 GSARP--AREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRL 354
P PSL+ P SP ALS A++ + SP L
Sbjct: 388 PIQVPHSLTSPSLQA----PPSPLALSSLQATT-------------SLGSPTLQATHSFL 430
Query: 355 VKAQYIPGAQAATRGLPGRAARRKP--PPLTRGRSVEQSPP 393
+ P A+ P R A P PPL S+ SPP
Sbjct: 431 TMS---PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 72.0 bits (175), Expect = 2e-12
Identities = 131/521 (25%), Positives = 173/521 (33%), Gaps = 116/521 (22%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
P +T P +PPS S S L PS P P S S +P +
Sbjct: 294 PLATPSPSAPPSP-------SAPPSLQTL-PSPPA------TPPSQATTSLGSPTLQATH 339
Query: 181 AAVPRSFSAPYPTAGGSAGP-------EACSSAERRARAGPFLTPSPL--HAVAMR---- 227
+ +P +P T A P +A S P TPSP +A+A+
Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 399
Query: 228 --SPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSV 285
SP P PP +P + A P+ + + A + P P
Sbjct: 400 PFSPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS---- 453
Query: 286 RQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPS- 344
P A+P P + P P L+ P +P AL+ + S A P P +PS
Sbjct: 454 ----PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 345 ----------PPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPR 394
PP +P Q P A+ P A R+PP P
Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS----PTLQAPRRPP-----------TPG 554
Query: 395 ERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKY---------- 444
+G R +A A G P +R S + S L G +S+ S P +
Sbjct: 555 PDTSVSGPRLTLALAPG-PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613
Query: 445 ------PTAEREEPRPPRPRRGPAPTLAAQAA-GSCRRWRSTAEIDAAD---------GR 488
P AE P RGPAP LA + A G+ W +AD G
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673
Query: 489 RVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLG--PLG------------- 533
AP A PGP P S + G S RLG PLG
Sbjct: 674 ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSR 733
Query: 534 ------RRGPAGGVGGGYGESESSASEGESPAFSSASSDSD 568
G AGG GGG G +E G + A A SD++
Sbjct: 734 TLLLAAAEGAAGGSGGGPGGAEGGGVTGGARA---ALSDAE 771
Score = 54.3 bits (129), Expect = 3e-07
Identities = 89/326 (27%), Positives = 111/326 (34%), Gaps = 61/326 (18%)
Query: 210 ARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDA----GGAG----RPLD---GYISALLR 258
ARA LTP P SPRP PP +P A G AG +PL G I
Sbjct: 19 ARAPGLLTPRP-----PGSPRP---PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 259 RRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPS-LERVGGHPTSP 317
AG RTS A G R + P SPG A P L + G ++
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 318 AALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATR-GLPGRAAR 376
++R A+ EA A A P G A A T GLP A
Sbjct: 131 ETVARGKAT----EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 186
Query: 377 RKPPPLTRG--RSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRA 434
+P P T G +SV + + R A G P +R S S + S R+
Sbjct: 187 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246
Query: 435 SAVPSGPPKYPTAEREEP--------RPPR---PRRGPAPTLAAQAAGSCRRWRSTAEID 483
G P+ P A +P RPP+ PR+ AP L ++
Sbjct: 247 GPSARGTPRAP-AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL---------- 295
Query: 484 AADGRRVRPRAPAARVPGPGPSPSAP 509
A P PSPSAP
Sbjct: 296 ------------ATPSPSAPPSPSAP 309
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 71.2 bits (173), Expect = 3e-12
Identities = 124/506 (24%), Positives = 163/506 (32%), Gaps = 108/506 (21%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
PS P S +T G + S+ P P L P AP +
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-----------LATPPPQAPPAL--- 400
Query: 181 AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSP 240
A+P + P P A P A S + L +P SP P PP +P
Sbjct: 401 -ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF------SPPPS--PPVQAP 451
Query: 241 DAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSAR 300
+ A P+ + + A + P P P A+P P +
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS--------PSATPPPQAPP 503
Query: 301 PAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPS-----------PPDSP 349
P P L+ P +P AL+ + S A P P +PS PP +P
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563
Query: 350 AEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEA 409
Q P A+ P A R+PP P +G R +A A
Sbjct: 564 PVLAAPLLQVPPSPPAS----PTLQAPRRPP-----------TPGPDTSVSGPRLTLALA 608
Query: 410 SGRRGSPRARKASRSQSETSLLGRASAVPSGPPKY----------------PTAEREEPR 453
G P +R S + S L G +S+ S P + P AE
Sbjct: 609 PG-PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667
Query: 454 PPRPRRGPAPTLAAQAA-GSCRRWRSTAEIDAAD---------GRRVRPRAPAARVPGPG 503
P RGPAP LA + A G+ W +AD G AP A PGP
Sbjct: 668 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 727
Query: 504 PSPSAPQRRLLYGCAGSDSECSAGRLG--PLG-------------------RRGPAGGVG 542
P S + G S RLG PLG G AGG G
Sbjct: 728 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 787
Query: 543 GGYGESESSASEGESPAFSSASSDSD 568
GG G +E G + A A SD++
Sbjct: 788 GGPGGAEGGGVTGGARA---ALSDAE 810
Score = 62.8 bits (151), Expect = 9e-10
Identities = 114/442 (25%), Positives = 148/442 (33%), Gaps = 87/442 (19%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSG---SSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVV 177
P+S G +PP+ S +S R GP +G+ S + AP+
Sbjct: 95 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 154
Query: 178 GARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPT 237
A R S P P G+ P + RR+RA P A + R RPPT
Sbjct: 155 ALSAGARRDTSGPTP---GTPSP----AMARRSRAAGTEVGLPRPAPSARP-----RPPT 202
Query: 238 DSP--DAGGAGRPLDGYISALLRRRRRRGAG-----------------QPRTSPGGADGG 278
+ P A S RRR G G P S A G
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 279 PRRQNSVRQ---------RPPDASPSPGSARPAREPSLERVGGHPTSPAAL--------- 320
PR Q RPP +P A PA P P+ AAL
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
Query: 321 SRAWASSWESEAA-------PEPAAPPA---APSPPDSPAEGRLVKAQYIPGAQAATRGL 370
+ +SS + A P P+APP+ PSPP +P + + P QA L
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFL 381
Query: 371 PGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRS-QSETS 429
P PPL S +PP + P A A S P + A+ S Q+ +
Sbjct: 382 PS-------PPL----SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430
Query: 430 LLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRR 489
L P PP P + P P P+ T +QA S AA +
Sbjct: 431 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL----------AAPPLQ 480
Query: 490 VRPRAPAA--RVPGPGPSPSAP 509
V P PA+ P P P AP
Sbjct: 481 VPPSPPASPPMSPSATPPPQAP 502
Score = 58.2 bits (139), Expect = 2e-08
Identities = 95/373 (25%), Positives = 124/373 (33%), Gaps = 83/373 (22%)
Query: 163 PKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLH 222
P+ +P+A V+GA AV R P A + G + E RAGP
Sbjct: 33 PRPPPPVTPAALRVLGAAGAVGRK-----PLAERAGGIGGATIPESAPRAGP-------- 79
Query: 223 AVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQ 282
RS R P P A G G R TSPG R
Sbjct: 80 ---TRSAGTSSRNPASRPPASGRGE---------------RAPPAKNTSPGPVSSPGRAS 121
Query: 283 NSVRQRPPDASPSPGSARPAREPSLERVG-GHPTSPAALSRAWASSWESEAAPEPAAPPA 341
+ R P P + R + E V G T S A + + P P P
Sbjct: 122 GTTR-------PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-- 172
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRG--RSVEQSPPRERPRA 399
SPA R +A G + GLP A +P P T G +SV +
Sbjct: 173 ------SPAMARRSRAA---GTEV---GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
Query: 400 AGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEP------- 452
+ R A G P +R S S + S R+ G P+ P A +P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP-AHPSQPKPKGLQA 279
Query: 453 -RPPR---PRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAP------------A 496
RPP+ PR+ AP L ++ +T AA + P P A
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPL----ATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335
Query: 497 ARVPGPGPSPSAP 509
+P PSPSAP
Sbjct: 336 TPLPLAPPSPSAP 348
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 70.9 bits (172), Expect = 3e-12
Identities = 108/422 (25%), Positives = 147/422 (34%), Gaps = 103/422 (24%)
Query: 119 EDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVG 178
++ TG S S SG SG S R G S R RP S + P P
Sbjct: 284 DEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS-AHSPPDKPSSPS 342
Query: 179 ARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTD 238
R + +AP P A G P S+ + R G
Sbjct: 343 PRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRA----------------------- 379
Query: 239 SPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGS 298
AGGAGR RRRRRR + R+S PRR+ R RP +P GS
Sbjct: 380 ---AGGAGR----------RRRRRRRRRRSRSSASA----PRRRGRRRPRP---APPRGS 419
Query: 299 ARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPS--------PPDSPA 350
+R SL R +R+ + S AP P P + + P
Sbjct: 420 SR-----SLSR-----------ARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPP 463
Query: 351 EGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRR------- 403
R PGA G G+++ R P P R S +SP + R R+A +R
Sbjct: 464 RARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRS 523
Query: 404 -------GRMAEASGR-----RGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREE 451
R + GR + RAR+ SRS S R S P + +A +
Sbjct: 524 PSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKR- 582
Query: 452 PRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDA-----------ADGRRVRPRAPAARVP 500
P P P+P+ ++ S RS + + + G R R R+P +R P
Sbjct: 583 ---PIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP-SRTP 638
Query: 501 GP 502
P
Sbjct: 639 SP 640
Score = 66.2 bits (160), Expect = 8e-11
Identities = 95/353 (26%), Positives = 124/353 (35%), Gaps = 71/353 (20%)
Query: 234 RPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRR--QNSVRQRPPD 291
RP T+SP S L R SP D G + Q S R P
Sbjct: 242 RPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPS 301
Query: 292 ASPSPGSARPAREP-SLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPA 350
S G P R S +R G H P + A SPPD P+
Sbjct: 302 PSGGSGWGSPQRNGGSGQRSGAHGGRPGS----------------------AHSPPDKPS 339
Query: 351 EGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEAS 410
+ + + +AA P P RG+ E PR P + GR GR A +
Sbjct: 340 --------------SPSPRVRDKAAAAAPTPPARGK--ESPSPRSAPSSQGRGGRAAGGA 383
Query: 411 GRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPR-PRRGPAPTLAAQA 469
GRR R R+ R +S +S ASA P+ R P PPR R + ++
Sbjct: 384 GRR---RRRRRRRRRSRSS----ASA-----PRRRGRRRPRPAPPRGSSRSLSRARSSSD 431
Query: 470 AGSCRRWRSTAEIDAAD------GRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSE 523
+GS R ++ G+R + R P AR PSP A RR G + +
Sbjct: 432 SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR-----GGPEGK 486
Query: 524 CSAGRLGPLGR-----RGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSG 571
S+ GP R R P+ + S S SP S D DG G
Sbjct: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK-KPLSRDKDGEG 538
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 69.7 bits (169), Expect = 8e-12
Identities = 101/432 (23%), Positives = 147/432 (34%), Gaps = 70/432 (16%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
PS GG +PP G+ + P P+G A+ PK + P
Sbjct: 1111 PSPKGGLATPPH--------KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162
Query: 181 AAVPRSFSAPYPTAGGSAGPEA--CSSAERRARAGPFLTP-SPLHAVAMRSPRPCGRPPT 237
A P AP A P+ + + + A P TP SP +A SP+ P
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222
Query: 238 DSPDAGGAGRPLDGYISALLRRRRRRGAGQ-PRTSPGGADGGPRRQNSVRQRPPDASPSP 296
+P + G L +GA P +P GGP PP +P+P
Sbjct: 1223 ATPPSPKGG----------LATPSPKGAPTTPAATPPSPKGGPATP------PPKGAPTP 1266
Query: 297 GSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDS-------- 348
+A P PSL+ P A + A + + P + P AP+PP +
Sbjct: 1267 PAATP---PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Query: 349 ----PAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRG 404
P +G P + T LP K P T +PP P G
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383
Query: 405 RMAEASGRRG----SPRARKAS--------RSQSETSLLGRASAVPS-----GPPKYPTA 447
M S +RG SP+ S + T + +A PS P P +
Sbjct: 1384 -MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 448 EREEPRPPRPRRGPA-------PTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPA--AR 498
++ P P+ GPA PTL A S + + ++ + + P PA
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 499 VPGPGPSPSAPQ 510
P PS+P+
Sbjct: 1503 PTLPAVIPSSPK 1514
Score = 59.3 bits (142), Expect = 1e-08
Identities = 100/426 (23%), Positives = 143/426 (33%), Gaps = 54/426 (12%)
Query: 101 SLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGS-SSYGRL-----GPSEP 154
SL G + + G + SP DSG S + SS G L PS P
Sbjct: 738 SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS-P 796
Query: 155 RGIYASER----PKSLGDASPSAP--EVVGARAAVPRSFSAPYPTAGGSAGPEACSSAER 208
G+ S + P G A P P + + V SF P + ++ ++
Sbjct: 797 LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASF-LPENSLSFQGSKDSPATTHS 855
Query: 209 RARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQP 268
P P+P AV SP+ PP ++P P A ++
Sbjct: 856 PTPPSPKGAPTP-SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
Query: 269 RTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSW 328
+SP A P + P +P+P +A P PS + GG PA S WA +
Sbjct: 915 SSSPKKARATPAPKGIPASPSPKGAPTPPAATP---PSPK--GG----PATPSPKWAPTP 965
Query: 329 ESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSV 388
+ P P PA PSP +P P + P PP +T
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAAT-----PPSPKGGPATPSPKGAPTPPAVT----- 1015
Query: 389 EQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAE 448
PP + A ++ +P + K S + A+ +P G P P A
Sbjct: 1016 ---PPSPKGSPAATPFPKGASTPPAATPPSPKGSPA---------ATPLPKGAPTTPAAT 1063
Query: 449 REEPR--PPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSP 506
P+ P P APT A S + +T A P PAA P P
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA------PMPPAATPPSPKGGL 1117
Query: 507 SAPQRR 512
+ P +
Sbjct: 1118 ATPPHK 1123
Score = 50.8 bits (120), Expect = 4e-06
Identities = 95/417 (22%), Positives = 145/417 (34%), Gaps = 54/417 (12%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
PSS GGP +P S + S G + P P GD P++P V+
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD--PTSPAVIPLS 1411
Query: 181 AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSP 240
P+ A T G+A P LTP + V+++ P T +P
Sbjct: 1412 ---PKKAPATPVTREGAATPSKGD-----------LTPPAVTPVSLKKA-----PATSAP 1452
Query: 241 DAGGA-----GRPLDGYISALLRR-----RRRRGAGQPRTSPG--GADGGPRRQNSVRQR 288
G A G P ++ + ++ + P+ +P G P +
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
Query: 289 PPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDS 348
P + +P S R P+ + +PA L+ A + P P PA P+P ++
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLS--KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570
Query: 349 PAEGRLVKAQYIPGAQAAT-RGLPGRAARRKPPPLTRGRSVE-QSPPRERPRAAGRRGRM 406
PA +A P +T +G P PP +T E +PP P + +
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 407 AEASGRRGSPRARKASRSQSETS----LLGRASAVP---SGPP--KYPTAEREEPRPPRP 457
G SP +S S TS + VP G P K PTA +E P P
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690
Query: 458 RRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLL 514
P T + ++ +T+ D P+A+ GP + LL
Sbjct: 1691 ESTPIITAPTRKGPQTKKSSATSPPICPD--------PSAKNGSKGPLSTVAPAPLL 1739
Score = 40.0 bits (92), Expect = 0.006
Identities = 84/418 (20%), Positives = 135/418 (32%), Gaps = 50/418 (11%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
P P + PS F +SS P P A+ KSLG+ P
Sbjct: 561 PLVQAAPKNSPS-------FQSTSS----SPEIPLSPEATLAKKSLGEPLPIGKPASSMT 609
Query: 181 AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSP 240
+ + + SA AGP++ + + P + PL S P G PT +
Sbjct: 610 SPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLE-----SADPAGVAPTTAK 664
Query: 241 DAGG----AGRPLDGYISALLRRRRRRGAGQPRTSP---GGADGGPRRQNSVRQRPPDAS 293
A L+G +S L + G T P ++ P + P A+
Sbjct: 665 GTSTYTTTASPFLEGTVS-LAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723
Query: 294 P--SPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAE 351
+P + PSL G +P + S S AP ++P P+ +
Sbjct: 724 LVLAPEIPKSVPSPSLPPAG----TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASA 779
Query: 352 GRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSP------PRERPRAAGRRGR 405
K A + + + + K PP +G + +P P A+
Sbjct: 780 TASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN 839
Query: 406 MAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRP----------- 454
G + SP + S ++ P P +E P P
Sbjct: 840 SLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 455 ---PRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAP 509
P P++ PA ++ + + R + I A+ + P PAA P P P+ P
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 69.3 bits (168), Expect = 1e-11
Identities = 144/578 (24%), Positives = 184/578 (31%), Gaps = 97/578 (16%)
Query: 50 PGMGGAEAE-DEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLE 108
PG+ G + D+ D E A E L LPG G +G + +
Sbjct: 1391 PGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGP-VGPPGKKGEKGD 1449
Query: 109 QESGRSSGFYEDPSSTG--GPDSPPSTFC--GDSGFSG----SSSYGRLGPSEPRGIYA- 159
E G + G P S G GP PP GD GF G + G GP P G
Sbjct: 1450 SEDG-APGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508
Query: 160 ---SERPKSLGDASPSAPEV----------VGARAAVPRSFSAPYPTAG--GSAGPEACS 204
+ RP + G P P G A V + + P G G AGP +
Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGAT 1568
Query: 205 SAERRARAGPFLTPS------------PLHAVAMRSPRPCGRPPTDSPDAGGAGRP---- 248
+ + P P+ P PP + D G G P
Sbjct: 1569 GVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVG 1628
Query: 249 ---LDGYISALLRRRRRRGAGQPRTSPG--------GADGGPRRQNSVRQRPPDASP--- 294
DG + +G P PG G G P + V ++ P
Sbjct: 1629 PRGRDGEVG-------EKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGED 1681
Query: 295 ----SPGSARPAREPSLERVGGHP-----TSPAALSRAWASSWESEAAPEPAAPPAAPSP 345
SPGS+ P + G P T P A + E P P P
Sbjct: 1682 GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEG---PRGPKGDPGL 1738
Query: 346 PDSPAEGRLVKAQYIPGAQA--ATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRR 403
P +P E + + PG Q RG G R PP L GRS +P AAG
Sbjct: 1739 PGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLD-GRSGLDG----KPGAAGPS 1793
Query: 404 GRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAP 463
G A+G+ G P + E L G PSGPP P E+ +P + P
Sbjct: 1794 GPNG-AAGKAGDPGRDGLPGLRGEQGLPG-----PSGPPGLPGKPGEDGKPGLNGKNGEP 1847
Query: 464 TLAAQAAGSCRRWRSTAE-IDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDS 522
+ + S A + DG + AP + GP P P G G
Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG--ILGPQGPPGLPGP---VGPPGQGF 1902
Query: 523 ECSAGRLGPLGRRGPAGGVG--GGYGESESSASEGESP 558
G GP G RG G G G GE G P
Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVP 1940
Score = 52.0 bits (123), Expect = 2e-06
Identities = 116/488 (23%), Positives = 145/488 (29%), Gaps = 72/488 (14%)
Query: 120 DPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASER-----PKSLGDASPSAP 174
DP G P P + GD G G G GP E GI E P S G P P
Sbjct: 1384 DPGPRGPPGLPGTAMKGDKGDRGER--GPPGPGEG-GIAPGEPGLPGLPGSPGPQGPVGP 1440
Query: 175 EVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGR 234
+ P GS G + GP P A+ + R
Sbjct: 1441 PGKKGEKGDSEDGAPGLPGQPGSPGEQ-----------GP---RGPPGAIGPKGDRGFPG 1486
Query: 235 PPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASP 294
P ++ + G G P L R GA P PG G + + RP D
Sbjct: 1487 PLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPT--GRQGEKGEPGRPGD--- 1541
Query: 295 SPGSARPA-REPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGR 353
P PA P E+ P P A+ + E P P P P P +
Sbjct: 1542 -PAVVGPAVAGPKGEKGDVGPAGPRG-----ATGVQGERGPPGLVLPGDPGPKGDPGDRG 1595
Query: 354 LV--KAQYIPGAQAATRGLPGRAARRKPP----PLTRGRSVEQSPPRERPRAAGRRGRMA 407
+ + P + G G R PP P R V + P G G+
Sbjct: 1596 PIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAG 1655
Query: 408 EASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAA 467
E G RG+P R + + G S P +R EP PP GP L
Sbjct: 1656 ER-GLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP----GPPGRLVD 1710
Query: 468 QAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAG 527
G+ + + D + PR P PG P AP G
Sbjct: 1711 TGPGAREKG------EPGDRGQEGPRGPKG---DPG-LPGAP-----------------G 1743
Query: 528 RLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASG 587
G G RGP G G + P S DG G P A +G
Sbjct: 1744 ERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAG 1803
Query: 588 GGAGAGAP 595
G P
Sbjct: 1804 DPGRDGLP 1811
Score = 52.0 bits (123), Expect = 2e-06
Identities = 149/617 (24%), Positives = 183/617 (29%), Gaps = 111/617 (17%)
Query: 50 PGMGGAEAEDEEDADEDEDAAAARRAAAAL-----EEQLEALPGLVWDLGQQLGDLSLES 104
PG+ G E + D ED ++ E PG + D G + E
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKG-EP 1721
Query: 105 GGLEQESGRSSGFYEDPSSTGGPDS--------PPSTFCGDSGFSGSSSYGRLGPSEPRG 156
G QE R G DP G P PP GD G G + G G P G
Sbjct: 1722 GDRGQEGPR--GPKGDPGLPGAPGERGIEGFRGPPGPQ-GDPGVRGPA--GEKGDRGPPG 1776
Query: 157 IYA-SERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPF 215
+ S G A PS P +A P P G G + +GP
Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLP-----GLRGEQGLPGP-----SGPP 1826
Query: 216 LTPSPLHAVAMRSPRPCGRPPTDSP-----DAGGAGRPLDGYISALLRRRRRRGAGQPRT 270
P P G+P + D G GR + S R R G R
Sbjct: 1827 GLPG--------KPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERG 1878
Query: 271 SPG--GADGGPRRQNSVRQRPPDASPSPGSARPARE------------PSLERVGGHPTS 316
+PG G G P V PG P + P + G P S
Sbjct: 1879 APGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGS 1938
Query: 317 -------------PAALSRAWASSWESEAA---PEPA------------APPAAPSPPDS 348
A+ R +W+ + P P PP P
Sbjct: 1939 VPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGF 1998
Query: 349 PAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAE 408
P E L + PG Q G PG A + PP G + E P P GR G + E
Sbjct: 1999 PGERGLKGDRGDPGPQ----GPPGLALGERGPPGPSGLAGEPGKPGI-PGLPGRAGGVGE 2053
Query: 409 AS-----GRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRP-RRGPA 462
A G RG R L G P GPP P +EP P +GP
Sbjct: 2054 AGRPGERGERGEKGERGEQGRDGPPGLPGTPG--PPGPPG-PKVSVDEPGPGLSGEQGPP 2110
Query: 463 PTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDS 522
A+ + G + P R G +P P R G AG +
Sbjct: 2111 GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPR--GQDGNPGLPGER---GMAGPE- 2164
Query: 523 ECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAA 582
G+ G G RGP G VGG A PA S G G P
Sbjct: 2165 ----GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG--RG 2218
Query: 583 TAASGGGAGAGAPAGPA 599
G G P GP+
Sbjct: 2219 LTGPTGAVGLPGPPGPS 2235
Score = 49.7 bits (117), Expect = 8e-06
Identities = 137/561 (24%), Positives = 163/561 (29%), Gaps = 120/561 (21%)
Query: 50 PGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQ 109
PG G E + D A A+AL E +E WD SG
Sbjct: 1927 PGERGLRGEPGSVPNVDRLLETAGIKASALREIVET-----WDES---------SGSFLP 1972
Query: 110 ESGRSSGFYEDPSSTGGPDSP-PSTFCGDSGFSGSSSYGRLGPSEPRGIYASER----PK 164
R G D G P P F G+ G G G GP P G+ ER P
Sbjct: 1973 VPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDR--GDPGPQGPPGLALGERGPPGPS 2030
Query: 165 SLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAV 224
L P P + G A P G G + + R GP P
Sbjct: 2031 GLA-GEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKG--ERGEQGRDGPPGLPG----- 2082
Query: 225 AMRSPRPCGRP-PTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGG-ADGGPRRQ 282
+P P G P P S D G G L + G + PG D GP+
Sbjct: 2083 ---TPGPPGPPGPKVSVDEPGPG---------LSGEQGPPGLKGAKGEPGSNGDQGPKGD 2130
Query: 283 NSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAA 342
V PG EP G+P P A PE
Sbjct: 2131 RGV----------PGIKGDRGEPGPRGQDGNPGLPGE---------RGMAGPEGKPGLQG 2171
Query: 343 PSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGR 402
P P P G PG A GL G A + P L +G E PP G
Sbjct: 2172 PRGPPGPVGGH-----GDPGPPGAP-GLAGPAGPQGPSGL-KGEPGETGPP-----GRGL 2219
Query: 403 RGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPA 462
G A G G P + L+G P G P P E +P P R A
Sbjct: 2220 TGPTG-AVGLPGPP---------GPSGLVG-----PQGSPGLPGQVGETGKPGAPGRDGA 2264
Query: 463 PTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAAR-VPGPGPSPSAPQRRLLYGCAGSD 521
DG R P P + +PGP P G G+
Sbjct: 2265 --------------------SGKDGDRGSPGVPGSPGLPGPVGPKGEP------GPTGAP 2298
Query: 522 SECSAGRLGPLGRRGPAGGVGGG-YGESESSASEG-ESPAFSSASSDSDGSGGLVWPQQL 579
+ G G G +G GG+ G GE + G P + G G
Sbjct: 2299 GQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQ 2358
Query: 580 VAATAASG--GGAGAGAPAGP 598
A G G G G P P
Sbjct: 2359 KGAPGPKGFKGDPGVGVPGSP 2379
Score = 48.9 bits (115), Expect = 1e-05
Identities = 78/288 (27%), Positives = 91/288 (31%), Gaps = 36/288 (12%)
Query: 335 EPAAP--PAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSP 392
+P P AP P P + PGA G PG R P ++ SP
Sbjct: 1273 DPGLPGRTGAPGPQGPPGSATAKGERGFPGAD----GRPGSPGRAGNPGTPGAPGLKGSP 1328
Query: 393 PRERPRA-AGRRGRMAEASGRRGSPRARKASRSQSETSLLGR-ASAVPSGPPKYPTAERE 450
PR G RG G +G P A L GR PSGPP P
Sbjct: 1329 GLPGPRGDPGERG----PRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPG-PRGPLG 1383
Query: 451 EPRPPRPRRGPAPTLAAQAAGSCRRWR-STAEIDAADGRRVRPRAPAARVPGPGPSPSAP 509
+P P P P + R E A G P P + PGP P
Sbjct: 1384 DPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGS--PGPQGPVGPP 1441
Query: 510 QRRLLYGCAGSDSECSA-------GRLGPLGRRGPAGGVG--------GGYGESESSASE 554
++ G DSE A G G G RGP G +G G GE+
Sbjct: 1442 GKKGEKG----DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGER 1497
Query: 555 GE-SPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAKV 601
G PA S G G P+ T G G P PA V
Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545
Score = 44.7 bits (104), Expect = 3e-04
Identities = 133/582 (22%), Positives = 168/582 (28%), Gaps = 127/582 (21%)
Query: 116 GFYEDPSSTG-----GPDSP--PSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSL-- 166
G + DP G GP P PS G+ G +G G GP+ G+ P L
Sbjct: 2180 GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVG 2239
Query: 167 GDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAM 226
SP P VG P A G G +S + R P + SP +
Sbjct: 2240 PQGSPGLPGQVGETGK---------PGAPGRDG----ASGKDGDRGSPGVPGSP----GL 2282
Query: 227 RSP-RPCGRP-PTDSPDAGGAGRP-----------LDGYISALLRRRRRRGAGQPRTSPG 273
P P G P PT +P G P L G + + RG PR G
Sbjct: 2283 PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKG 2342
Query: 274 -----GADGGPRRQNSVRQRPPDASPS------PGSARPAREPSLERVGGHPTSPAALS- 321
G G P P PGS P P ++ G P P A
Sbjct: 2343 EAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGV 2402
Query: 322 ---------------------RAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYI 360
R A E P P PP P P L +
Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462
Query: 361 PGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPR-------------------AAG 401
PG GLPG R P + R + P +E PR +AG
Sbjct: 2463 PGV-----GLPGPRGERGEPGI---RGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAG 2514
Query: 402 RRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGP 461
+G +++ G P R A E G K P + +P + P
Sbjct: 2515 LKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDG------DKGPRGDNGDPGDKGSKGEP 2568
Query: 462 APTLAAQAAG-----SCRRWRSTAEIDAADGRRVRPRAPAAR-----VPGPGPSPSAPQR 511
+A G + A I G + P R V GP +R
Sbjct: 2569 GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGER 2628
Query: 512 RLLYGCAGSDSECSAGRLGPLGRRGPAG-----GVGGGYGESESSASEGESPAFSSASSD 566
+ C + G GP GR G AG G G G+S + EG D
Sbjct: 2629 GVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFD 2688
Query: 567 -------SDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAKV 601
G G + SG AG P P V
Sbjct: 2689 GQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSV 2730
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 66.6 bits (161), Expect = 6e-11
Identities = 132/532 (24%), Positives = 168/532 (31%), Gaps = 101/532 (18%)
Query: 126 GPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDASPSAPE-VVGARAAV 183
GP PP G G +G G+ G G + PK G+ P+ P+ G
Sbjct: 435 GPRGPP----GPQGATGPLGPKGQTGEPGIAGFKGEQGPK--GEPGPAGPQGAPGPAGEE 488
Query: 184 PRSFSAPYPTAGGSAGPEACSSAE-RRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDA 242
+ + P G GP A R G P A R P P + D
Sbjct: 489 GKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 548
Query: 243 GGAGRPLDGYISALLRRRRRRGAG-QPRTSPGGADG-----GPRRQNSVRQRP------- 289
G G P G A R AG Q + P GA G GP R +P
Sbjct: 549 GRPGEP--GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 606
Query: 290 -PDASPSPGSARPAREPSLERVGGHPTSPAALSRAW-------ASSWESEAAPEPAAPPA 341
A+ PG A P + G P A A + AP P+
Sbjct: 607 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 666
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAA--------TRGLPGRAARRKPPPLTRGRSVEQSPP 393
P PP P EG Q +PG A RG PG L R + +P
Sbjct: 667 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726
Query: 394 RERPRAA-------------------GRRGR--MAEASGRRGSPRARKASRSQSETSLLG 432
+ P+ A G RG +A G RG + + + G
Sbjct: 727 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--G 784
Query: 433 RASAVPSGPPKYPTA--EREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRV 490
R P GPP A E+ E PP GPA + A+ A +
Sbjct: 785 RGLTGPIGPPGPAGANGEKGEVGPP----GPAGSAGARGA-------------PGERGET 827
Query: 491 RPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSA-GRLGPLGRRGPAG--GVGGGYGE 547
P PA GP + P + G AG + A G GP G GP G GV G G
Sbjct: 828 GPPGPAG-FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA 886
Query: 548 SESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPA 599
+ G ++ G+ G V P S G G P GP+
Sbjct: 887 RGAQGPPG--------ATGFPGAAGRVGP-------PGSNGNPGPPGPPGPS 923
Score = 63.5 bits (153), Expect = 5e-10
Identities = 147/544 (27%), Positives = 173/544 (31%), Gaps = 108/544 (19%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDAS-----PSAP 174
P GP PP GD G +G G GP P+G L P
Sbjct: 238 PMGPRGPPGPPGK-PGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD 296
Query: 175 EVVGARAAVPRSFSAPYPTAGGSAGPEACSSAE-RRARAGPFLTPSPLHAVAMR----SP 229
G A + P GS GP R R G P A R P
Sbjct: 297 GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG------PAGAAGARGNDGQP 350
Query: 230 RPCGRPPTDSPDAGGAGRPLDGYISAL-----LRRRRRRGAGQPRTSPG----------- 273
P G PP AGG G P G A R GA PR PG
Sbjct: 351 GPAG-PPGPVGPAGGPGFP--GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 407
Query: 274 ---GADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWES 330
G DG P + S P + +PG P P + G + ++
Sbjct: 408 GNPGTDGIPGAKGSA--GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 465
Query: 331 EAAPEPAAPPAAPSPPDSPA--EGRL--------VKAQYIPGAQAA--TRGLPGR--AAR 376
E P+ PA P PA EG+ V PG + A RG PG+ A
Sbjct: 466 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 525
Query: 377 RKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASA 436
K P RG S P A G GR G G P AR + + G+
Sbjct: 526 PKGAPGERGPSGLAGP----KGANGDPGR----PGEPGLPGARGLTGRPGDAGPQGKVG- 576
Query: 437 VPSGPPKYPTAEREEPRPPRPR--RG-------PAPTLAAQAAGSCRRWRSTAEIDAADG 487
PSG P E P PP P+ RG P P A G G
Sbjct: 577 -PSGAP----GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA-------------G 618
Query: 488 RRVRPRAPAAR-VPG----------PGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRG 536
+ P AP R +PG PGP+ A +R S + G GP G G
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 678
Query: 537 PAG--GVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGA 594
G GV G G GE S G+ GL P+ L T + G GA
Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERG--FPGERGSPGAQGLQGPRGL-PGTPGTDGPKGASG 735
Query: 595 PAGP 598
PAGP
Sbjct: 736 PAGP 739
Score = 62.4 bits (150), Expect = 1e-09
Identities = 133/531 (25%), Positives = 162/531 (30%), Gaps = 104/531 (19%)
Query: 119 EDPSSTGGPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDASPSAPEVV 177
+ P GP PP G G G G G + P+G GD PE
Sbjct: 728 DGPKGASGPAGPPGAQ-GPPGLQGMPGERGAAGIAGPKG--------DRGDVGEKGPEGA 778
Query: 178 GARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPT 237
+ R + P G GP + + GP P P + R P R T
Sbjct: 779 PGKDG-GRGLTGPI----GPPGPAGANG--EKGEVGP---PGPAGSAGARGA-PGERGET 827
Query: 238 DSPD-AGGAGRP-LDGYISALLRRR---RRRGAGQPRTS-PGGADG--------GPRRQN 283
P AG AG P DG A + ++ AG P P GA G GP+
Sbjct: 828 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887
Query: 284 SVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE-------- 335
Q PP A+ PG+A P G P P + ++ P
Sbjct: 888 GA-QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 946
Query: 336 --PAAPPAAPSPP--DSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPP--PLTRGRSVE 389
PA PP P D P+ Q GLPG+ R P P G +
Sbjct: 947 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 1006
Query: 390 QSPP-----RERPRAAGRRGRMAEAS--GRRGSPRA---------RKASRSQSETSLLGR 433
Q P R P G G A GR GSP A + ET +G
Sbjct: 1007 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 1066
Query: 434 ASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPR 493
A GPP P P P ++G AQ I G PR
Sbjct: 1067 PGA--PGPPGSPG-----PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG----PR 1115
Query: 494 APAARVPGPGPSPSAPQRRL--LYGCAG----SDSECSAGRLGPLGRRGPAGGVGGGYGE 547
PG R L G G S + ++G GP G RGP G VG
Sbjct: 1116 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVG----- 1170
Query: 548 SESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGP 598
S DG+ G+ P SG AG P P
Sbjct: 1171 ----------------PSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP 1205
Score = 58.9 bits (141), Expect = 1e-08
Identities = 111/425 (26%), Positives = 133/425 (31%), Gaps = 104/425 (24%)
Query: 193 TAGGSAGPEACSS--AERRARAGPFLTPSPLHAVAMRSPR-------------PCGRP-- 235
TA G GP+ + + GP P P + PR P GR
Sbjct: 95 TASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 154
Query: 236 PTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPS 295
P + G G P L + AG GGA G V Q P
Sbjct: 155 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG------VMQGPMGPMGP 208
Query: 296 PGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLV 355
G PA P + G+P P P P P PP P +
Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPG-----------EPGVSGPMGPRGPPGPPGKPGDD--- 254
Query: 356 KAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGR--MAEASGRR 413
G PG+A R PP R +P P G RG + A G
Sbjct: 255 ----------GEAGKPGKAGERGPPGPQGARGFPGTPGL--PGVKGHRGYPGLDGAKGEA 302
Query: 414 GSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSC 473
G+P + S S E G P GP P R R GPA AA A G+
Sbjct: 303 GAPGVKGESGSPGENGSPG-----PMGPRGLPGE--------RGRTGPAG--AAGARGN- 346
Query: 474 RRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLG 533
D G P P GPG P AP + G GP G
Sbjct: 347 ---------DGQPGP-AGPPGPVGPAGGPG-FPGAPGAK--------------GEAGPTG 381
Query: 534 RRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAG 593
RGP G G GE + S G PA +S + +DG G A ++G AG
Sbjct: 382 ARGPE-GAQGPRGEPGTPGSPG--PAGASGNPGTDGIPG---------AKGSAGAPGIAG 429
Query: 594 APAGP 598
AP P
Sbjct: 430 APGFP 434
Score = 36.2 bits (82), Expect = 0.094
Identities = 84/337 (24%), Positives = 105/337 (31%), Gaps = 54/337 (16%)
Query: 119 EDPSSTGGPDSPPST-----FCGDSGFSGSSSY-GRLGPSEPRGIYASERPKSLGDASPS 172
+ PS GP P G G G + G GPS G + P + GD P
Sbjct: 962 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA--PGASGDRGPP 1019
Query: 173 APEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAV-AMRSPRP 231
P VG P + P G P A R AG AV A +P P
Sbjct: 1020 GP--VG-----PPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072
Query: 232 CGRPPTDSP-----DAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVR 286
G P P D G AG S R +G PR G A G P +
Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA-GEPGERGLKG 1131
Query: 287 QR----------PPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE- 335
R PP S G++ PA PS R P P+ + A+ P
Sbjct: 1132 HRGFTGLQGLPGPPGPSGDQGASGPAG-PSGPRGPPGPVGPSG--KDGANGIPGPIGPPG 1188
Query: 336 ---------PAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGR 386
PA PP P PP P PG G R K P +
Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGP---------PGPGIDMSAFAGLGPREKGPDPLQYM 1239
Query: 387 SVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASR 423
+Q+ R A + + + S R+ + SR
Sbjct: 1240 RADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSR 1276
Score = 31.2 bits (69), Expect = 3.0
Identities = 48/184 (26%), Positives = 56/184 (30%), Gaps = 27/184 (14%)
Query: 436 AVPSGPPKYPTAEREEPRP------PRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRR 489
A SG P P ++ EP P+ GP Q R + GR
Sbjct: 94 ATASGQPG-PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152
Query: 490 VRPRAPAARVPGPGPSPSAPQRRLLYG-------------CAGSDSECSAGRLGPLGRRG 536
P P PGP P P L G G+ G +GP+G RG
Sbjct: 153 GEPGTPGN--PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG 210
Query: 537 PAG--GVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGA 594
P G G G G + GE P S G P A G AG
Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGE-PGVSGPMGPRGPPGPPGKPGD--DGEAGKPGKAGERG 267
Query: 595 PAGP 598
P GP
Sbjct: 268 PPGP 271
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 66.6 bits (161), Expect = 6e-11
Identities = 132/532 (24%), Positives = 168/532 (31%), Gaps = 101/532 (18%)
Query: 126 GPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDASPSAPE-VVGARAAV 183
GP PP G G +G G+ G G + PK G+ P+ P+ G
Sbjct: 366 GPRGPP----GPQGATGPLGPKGQTGEPGIAGFKGEQGPK--GEPGPAGPQGAPGPAGEE 419
Query: 184 PRSFSAPYPTAGGSAGPEACSSAE-RRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDA 242
+ + P G GP A R G P A R P P + D
Sbjct: 420 GKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 479
Query: 243 GGAGRPLDGYISALLRRRRRRGAG-QPRTSPGGADG-----GPRRQNSVRQRP------- 289
G G P G A R AG Q + P GA G GP R +P
Sbjct: 480 GRPGEP--GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 537
Query: 290 -PDASPSPGSARPAREPSLERVGGHPTSPAALSRAW-------ASSWESEAAPEPAAPPA 341
A+ PG A P + G P A A + AP P+
Sbjct: 538 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 597
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAA--------TRGLPGRAARRKPPPLTRGRSVEQSPP 393
P PP P EG Q +PG A RG PG L R + +P
Sbjct: 598 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657
Query: 394 RERPRAA-------------------GRRGR--MAEASGRRGSPRARKASRSQSETSLLG 432
+ P+ A G RG +A G RG + + + G
Sbjct: 658 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG--G 715
Query: 433 RASAVPSGPPKYPTA--EREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRV 490
R P GPP A E+ E PP GPA + A+ A +
Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPP----GPAGSAGARGA-------------PGERGET 758
Query: 491 RPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSA-GRLGPLGRRGPAG--GVGGGYGE 547
P PA GP + P + G AG + A G GP G GP G GV G G
Sbjct: 759 GPPGPAG-FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA 817
Query: 548 SESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPA 599
+ G ++ G+ G V P S G G P GP+
Sbjct: 818 RGAQGPPG--------ATGFPGAAGRVGP-------PGSNGNPGPPGPPGPS 854
Score = 63.5 bits (153), Expect = 5e-10
Identities = 147/544 (27%), Positives = 173/544 (31%), Gaps = 108/544 (19%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDAS-----PSAP 174
P GP PP GD G +G G GP P+G L P
Sbjct: 169 PMGPRGPPGPPGK-PGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD 227
Query: 175 EVVGARAAVPRSFSAPYPTAGGSAGPEACSSAE-RRARAGPFLTPSPLHAVAMR----SP 229
G A + P GS GP R R G P A R P
Sbjct: 228 GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG------PAGAAGARGNDGQP 281
Query: 230 RPCGRPPTDSPDAGGAGRPLDGYISAL-----LRRRRRRGAGQPRTSPG----------- 273
P G PP AGG G P G A R GA PR PG
Sbjct: 282 GPAG-PPGPVGPAGGPGFP--GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 338
Query: 274 ---GADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWES 330
G DG P + S P + +PG P P + G + ++
Sbjct: 339 GNPGTDGIPGAKGSA--GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 396
Query: 331 EAAPEPAAPPAAPSPPDSPA--EGRL--------VKAQYIPGAQAA--TRGLPGR--AAR 376
E P+ PA P PA EG+ V PG + A RG PG+ A
Sbjct: 397 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 456
Query: 377 RKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASA 436
K P RG S P A G GR G G P AR + + G+
Sbjct: 457 PKGAPGERGPSGLAGP----KGANGDPGR----PGEPGLPGARGLTGRPGDAGPQGKVG- 507
Query: 437 VPSGPPKYPTAEREEPRPPRPR--RG-------PAPTLAAQAAGSCRRWRSTAEIDAADG 487
PSG P E P PP P+ RG P P A G G
Sbjct: 508 -PSGAP----GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA-------------G 549
Query: 488 RRVRPRAPAAR-VPG----------PGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRG 536
+ P AP R +PG PGP+ A +R S + G GP G G
Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 609
Query: 537 PAG--GVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGA 594
G GV G G GE S G+ GL P+ L T + G GA
Sbjct: 610 KPGDQGVPGEAGAPGLVGPRGERG--FPGERGSPGAQGLQGPRGL-PGTPGTDGPKGASG 666
Query: 595 PAGP 598
PAGP
Sbjct: 667 PAGP 670
Score = 62.4 bits (150), Expect = 1e-09
Identities = 133/531 (25%), Positives = 162/531 (30%), Gaps = 104/531 (19%)
Query: 119 EDPSSTGGPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDASPSAPEVV 177
+ P GP PP G G G G G + P+G GD PE
Sbjct: 659 DGPKGASGPAGPPGAQ-GPPGLQGMPGERGAAGIAGPKG--------DRGDVGEKGPEGA 709
Query: 178 GARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPT 237
+ R + P G GP + + GP P P + R P R T
Sbjct: 710 PGKDG-GRGLTGPI----GPPGPAGANG--EKGEVGP---PGPAGSAGARGA-PGERGET 758
Query: 238 DSPD-AGGAGRP-LDGYISALLRRR---RRRGAGQPRTS-PGGADG--------GPRRQN 283
P AG AG P DG A + ++ AG P P GA G GP+
Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818
Query: 284 SVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE-------- 335
Q PP A+ PG+A P G P P + ++ P
Sbjct: 819 GA-QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 877
Query: 336 --PAAPPAAPSPP--DSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPP--PLTRGRSVE 389
PA PP P D P+ Q GLPG+ R P P G +
Sbjct: 878 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 937
Query: 390 QSPP-----RERPRAAGRRGRMAEAS--GRRGSPRA---------RKASRSQSETSLLGR 433
Q P R P G G A GR GSP A + ET +G
Sbjct: 938 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 997
Query: 434 ASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPR 493
A GPP P P P ++G AQ I G PR
Sbjct: 998 PGA--PGPPGSPG-----PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG----PR 1046
Query: 494 APAARVPGPGPSPSAPQRRL--LYGCAG----SDSECSAGRLGPLGRRGPAGGVGGGYGE 547
PG R L G G S + ++G GP G RGP G VG
Sbjct: 1047 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVG----- 1101
Query: 548 SESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGP 598
S DG+ G+ P SG AG P P
Sbjct: 1102 ----------------PSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP 1136
Score = 58.5 bits (140), Expect = 2e-08
Identities = 87/319 (27%), Positives = 103/319 (32%), Gaps = 81/319 (25%)
Query: 282 QNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPA 341
Q V Q P G PA P + G+P P P P
Sbjct: 126 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG-----------EPGVSGPMGPRG 174
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAG 401
P PP P + G PG+A R PP R +P P G
Sbjct: 175 PPGPPGKPGDD-------------GEAGKPGKAGERGPPGPQGARGFPGTPGL--PGVKG 219
Query: 402 RRGR--MAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRR 459
RG + A G G+P + S S E G P GP P R R
Sbjct: 220 HRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG-----PMGPRGLPGE--------RGRT 266
Query: 460 GPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAG 519
GPA AA A G+ D G P P GPG P AP +
Sbjct: 267 GPAG--AAGARGN----------DGQPGP-AGPPGPVGPAGGPG-FPGAPGAK------- 305
Query: 520 SDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQL 579
G GP G RGP G G GE + S G PA +S + +DG G
Sbjct: 306 -------GEAGPTGARGPE-GAQGPRGEPGTPGSPG--PAGASGNPGTDGIPG------- 348
Query: 580 VAATAASGGGAGAGAPAGP 598
A ++G AGAP P
Sbjct: 349 --AKGSAGAPGIAGAPGFP 365
Score = 36.2 bits (82), Expect = 0.094
Identities = 84/337 (24%), Positives = 105/337 (31%), Gaps = 54/337 (16%)
Query: 119 EDPSSTGGPDSPPST-----FCGDSGFSGSSSY-GRLGPSEPRGIYASERPKSLGDASPS 172
+ PS GP P G G G + G GPS G + P + GD P
Sbjct: 893 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA--PGASGDRGPP 950
Query: 173 APEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAV-AMRSPRP 231
P VG P + P G P A R AG AV A +P P
Sbjct: 951 GP--VG-----PPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1003
Query: 232 CGRPPTDSP-----DAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVR 286
G P P D G AG S R +G PR G A G P +
Sbjct: 1004 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA-GEPGERGLKG 1062
Query: 287 QR----------PPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE- 335
R PP S G++ PA PS R P P+ + A+ P
Sbjct: 1063 HRGFTGLQGLPGPPGPSGDQGASGPAG-PSGPRGPPGPVGPSG--KDGANGIPGPIGPPG 1119
Query: 336 ---------PAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGR 386
PA PP P PP P PG G R K P +
Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGP---------PGPGIDMSAFAGLGPREKGPDPLQYM 1170
Query: 387 SVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASR 423
+Q+ R A + + + S R+ + SR
Sbjct: 1171 RADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSR 1207
Score = 30.0 bits (66), Expect = 6.7
Identities = 39/157 (24%), Positives = 48/157 (30%), Gaps = 13/157 (8%)
Query: 452 PRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQR 511
P+ P +GPA + + + DG P P P P P
Sbjct: 49 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGG 108
Query: 512 RLLYGCAGSDSECSAGR--------LGPLGRRGPAG--GVGGGYGESESSASEGESPAFS 561
AG E + G +GP+G RGP G G G G + GE P S
Sbjct: 109 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGE-PGVS 167
Query: 562 SASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGP 598
G P A G AG P GP
Sbjct: 168 GPMGPRGPPGPPGKPGD--DGEAGKPGKAGERGPPGP 202
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 66.6 bits (161), Expect = 6e-11
Identities = 87/327 (26%), Positives = 112/327 (34%), Gaps = 80/327 (24%)
Query: 268 PRTSPGGADGGPRRQNSVRQRPPDA-SPSPGSARPAREPSLERVGGHPTSPAALSRAWAS 326
PR + + GP R ++ P++ P+P PA E SLER P A +S S
Sbjct: 1041 PRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERA---PAPSAVVS----S 1093
Query: 327 SWESEAAPEPAAP---------------PAAPSPPDSPAEGRL---VKAQYIPGAQAATR 368
E AP P P P P +P GRL + G A
Sbjct: 1094 RNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPG 1153
Query: 369 GLPGRAARRK-----------------PPPLTRGRSVEQSPPRERPRAAGRRGRMAEASG 411
G PG K PPP + R +E +PPR RP A G
Sbjct: 1154 GGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVA--------PEG 1205
Query: 412 RRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAG 471
G+P SR+ +T+L G G P P ER+ P PR P
Sbjct: 1206 EPGAP----DSRAGGDTALSG------DGDP--PKPERKGPEMPRLFLDLGPPQG----- 1248
Query: 472 SCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGP 531
++ +I A R P P PGP P P G+D+ + G G
Sbjct: 1249 ------NSEQIKARLSRLSLALPPLTLTPFPGPGPRRPP------WEGADAGAAGGEAGG 1296
Query: 532 LGRRGPAGGVGGGYGESESSASEGESP 558
G GPA G E E E +P
Sbjct: 1297 AGAPGPAEEDGEDEDEDEEEDEEAAAP 1323
Score = 43.1 bits (100), Expect = 8e-04
Identities = 122/548 (22%), Positives = 166/548 (30%), Gaps = 109/548 (19%)
Query: 119 EDPSSTGGPDS---PPSTFCGDSG------FSGSSSYGRLGPSEPRGIYASERPKSLGDA 169
+ PS+ P S P GDSG FS ++ G +E G+ P D
Sbjct: 800 DPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPD- 858
Query: 170 SPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSP 229
P AP +P PT E + R L A P
Sbjct: 859 -PGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATA-RETGP 916
Query: 230 RPCGRPPTDSPDAGGAGR----------------PLDGYISALLRRRRRRGAGQPRTSPG 273
R GR P + G R P++G ++ L +R + + +
Sbjct: 917 RKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNG-VTVLENGDQRAPGIEEKAAEN 975
Query: 274 GADGGPRRQNSVRQ-------------------RPPDASP----SPGSARPAREPSLERV 310
GA G P R+ V + R P+A + G P E +
Sbjct: 976 GALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSEN 1035
Query: 311 GG----HPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAA 366
GG T + W + E PE P AP+ + E L +A P A +
Sbjct: 1036 GGLRFPRNTERPPETGPWRAPGPWEKTPESWGP--APTIGEPAPETSLERAP-APSAVVS 1092
Query: 367 TRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQS 426
+R P PL P+ G R E G +P A +
Sbjct: 1093 SRN----GGETAPGPLGPA-------PKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSG 1141
Query: 427 ETSLLGRASAVPSGP-----PKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAE 481
+ +G +A GP K + P+PP P P P
Sbjct: 1142 GRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPE----------------- 1184
Query: 482 IDAADGRRVRPRAPAARVP-GPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLG-RRGPAG 539
A RR+ P P AR P P AP R AG D+ S P R+GP
Sbjct: 1185 ---AQPRRLEPAPPRARPEVAPEGEPGAPDSR-----AGGDTALSGDGDPPKPERKGPEM 1236
Query: 540 -------GVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGA 592
G G E + S A + G P A A+GG AG
Sbjct: 1237 PRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGG 1296
Query: 593 GAPAGPAK 600
GPA+
Sbjct: 1297 AGAPGPAE 1304
Score = 40.8 bits (94), Expect = 0.004
Identities = 61/246 (24%), Positives = 82/246 (33%), Gaps = 47/246 (19%)
Query: 148 RLGPSEPRGIYASERPKSLGDASPSAPEV-VGARAAVPRSFSAPYPTAGG--------SA 198
RL P+ PR RP+ + P AP+ G A+ P P G
Sbjct: 1189 RLEPAPPRA-----RPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDL 1243
Query: 199 GPEACSSAERRARAGPF-LTPSPLHAVAMRSPRPCGRPPTDSPDAG-------GAGRP-- 248
GP +S + +AR L PL P P RPP + DAG GAG P
Sbjct: 1244 GPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGP-RRPPWEGADAGAAGGEAGGAGAPGP 1302
Query: 249 -------------LDGYISALLRRRRRRGAGQPRTSP-----GGADGGPRRQNSVRQRPP 290
D +A RG G+ R +P AD R + P
Sbjct: 1303 AEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSP 1362
Query: 291 DASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE----PAAPPAAPSPP 346
+ P + R+ + G T + +A PE P+ PPA P+PP
Sbjct: 1363 RGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPP 1422
Query: 347 DSPAEG 352
G
Sbjct: 1423 HPATPG 1428
Score = 37.0 bits (84), Expect = 0.055
Identities = 99/389 (25%), Positives = 122/389 (31%), Gaps = 76/389 (19%)
Query: 151 PSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAP--YPTAGGSAGPEACSSAER 208
P +P G+ A + P+ A P++V A P F AP +P ++G S +
Sbjct: 588 PLDP-GVPAPQAPQ----APSEVPQLVSETWASPL-FPAPRPFPAQSSASGSFLLSGWDP 641
Query: 209 RAR-AGPFLTPSPLHAVAMRSPRPC----------GRPPTDSPDAGGAGR-------PL- 249
R AG L P + R P P DS GG PL
Sbjct: 642 EGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLC 701
Query: 250 --DGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSL 307
+G S L R AG G P +S+R + P A PA P
Sbjct: 702 SREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLP-MAPPASAP-- 758
Query: 308 ERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAAT 367
P L A A + P APP P PP +PA+ A P + A+
Sbjct: 759 ------PEFLDPLMGAAAPQYPGRGPPP--APPPPPPPPRAPAD---PAASPDPPSAVAS 807
Query: 368 RGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSE 427
G + P P E P P A G AE G PR R
Sbjct: 808 PG----SGLSSPGPKPGDSGYETETPFS-PEGAFPGGGAAE---EEGVPRPR-------- 851
Query: 428 TSLLGRASAVPSGPPKYPTAEREEPRP-PRPRRGP--APTLAAQAAGS----CRRWRSTA 480
P PP P A R P P P P GP PT Q + R T
Sbjct: 852 ---------APPEPPD-PGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTR 901
Query: 481 EIDAADGRRVRPRAPAARVPGPGPSPSAP 509
+ G R P GPG P
Sbjct: 902 NLLGEKGATARETGPRKAGRGPGNREKVP 930
Score = 32.7 bits (73), Expect = 1.0
Identities = 85/352 (24%), Positives = 118/352 (33%), Gaps = 59/352 (16%)
Query: 35 ERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAAARRAAAALEEQL-EALPGLVWDL 93
E Q R++ A A+P + D+ D A + E+ +P L DL
Sbjct: 1184 EAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDL 1243
Query: 94 GQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSS--YGRLGP 151
G G+ L + S P GP PP D+G +G + G GP
Sbjct: 1244 GPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGA-DAGAAGGEAGGAGAPGP 1302
Query: 152 SEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRAR 211
+E G E + D +AP R+ +AP P SA +A
Sbjct: 1303 AEEDGEDEDEDEEE--DEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAA-------- 1352
Query: 212 AGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTS 271
PL + ++SPR GA P D S L R+R+ T
Sbjct: 1353 -------RPLRGL-LKSPR-------------GADEPED---SELERKRKMVSFHGDVTV 1388
Query: 272 PGGADGGPRRQNSVRQRPP--DASPSPGSARPAREPSLERVGGHPTSPAAL--SRAWASS 327
P + SV Q PP D PS A P G P++ + S WA
Sbjct: 1389 YLFDQETPTNELSV-QAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAED 1447
Query: 328 WESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKP 379
+ P PP P PP L +++ T G P RA +P
Sbjct: 1448 F-------PLLPP--PGPP-------LCFSRFSVSPALETPGPPARAPDARP 1483
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 66.2 bits (160), Expect = 8e-11
Identities = 136/571 (23%), Positives = 189/571 (33%), Gaps = 73/571 (12%)
Query: 50 PGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQ 109
PG+ G E ++ + E R A + +PG + G+ + GL
Sbjct: 425 PGLRGGAGEPGKNGAKGEPGPRGERGEAGIP----GVPGAKGEDGKDGSPGEPGANGLPG 480
Query: 110 ESG-RSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGD 168
+G R + + P+ GP+ P G+ G +G G GP+ PRG A+ P D
Sbjct: 481 AAGERGAPGFRGPA---GPNGIP----GEKGPAGER--GAPGPAGPRG--AAGEPGR--D 527
Query: 169 ASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPL-HAVAMR 227
P P + G +P S P G P S R GP P M
Sbjct: 528 GVPGGPGMRG----MPGSPGGP----GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMG 579
Query: 228 SPRPCGRP--PTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGG--ADGGPRRQN 283
P P G P + + GG G P +G P T PGG D GP
Sbjct: 580 FPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP-TGPGGDKGDTGPPGPQ 638
Query: 284 SVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAA---------- 333
++ P P + +P EP + G P +P A A
Sbjct: 639 GLQGLPGTGGPPGENGKPG-EPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697
Query: 334 ---PEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQ 390
P P A PP P Q +PG + G PG + P G +
Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL-GSPGPKGDKGEPG---GPGADG 753
Query: 391 SPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAERE 450
P ++ PR G G + G G P + + + G P G P ER
Sbjct: 754 VPGKDGPR--GPTGPIGPP-GPAGQPGDKGEGGAPGLPGIAG-----PRGSP----GERG 801
Query: 451 EPRPPRPRRGP-APTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAP 509
E PP P P AP + G R A G + P P G P+ P
Sbjct: 802 ETGPPGPAGFPGAPGQNGEPGGKGER--------GAPGEKGEGGPPGVAGPPGGSGPAGP 853
Query: 510 QR-RLLYGCAGSDS-ECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDS 567
+ + G GS +AG G G GP G G S + + P + ++ +
Sbjct: 854 PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA 913
Query: 568 DGSGGLVWPQQLVAATAASGGGAGAGAPAGP 598
GS G+ P+ G G P P
Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP 944
Score = 66.2 bits (160), Expect = 8e-11
Identities = 142/541 (26%), Positives = 171/541 (31%), Gaps = 99/541 (18%)
Query: 119 EDPSSTGGPDSPPSTFCGDSGFSGS----SSYGRLGPS----EPRGIYASERPKSLGDAS 170
E GP PP G G G G GP EP G A P G
Sbjct: 704 EGGKGAAGPPGPPGA-AGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRG 762
Query: 171 PSAPEVVGARAAVPRSFS-APYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSP 229
P+ P A P P G AGP S R GP P+ ++
Sbjct: 763 PTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRG--SPGERGETGP-PGPAGFPGAPGQNG 819
Query: 230 RPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPG--------GADGGPRR 281
P G+ +P G G P G G P PG G+ GGP
Sbjct: 820 EPGGKGERGAPGEKGEGGP-PGVAGP-------PGGSGPAGPPGPQGVKGERGSPGGPGA 871
Query: 282 QNSVRQR----PPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAA-PEP 336
R PP ++ +PG P+ P + G + A S + +A P
Sbjct: 872 AGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGE 931
Query: 337 AAPPAAPSPPDSPAEGRLVKAQYIPGAQ--AATRGLPGRAARRKPP--------PLTRGR 386
P A PP +P + I GA+ A G+PG P P G
Sbjct: 932 KGSPGAQGPPGAPGPLGIAG---ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGL 988
Query: 387 SVEQSPPRER--PRAAGRRGRMAEAS--------GRRGSPRARKASRSQSETSLLGRASA 436
S E+ PP + P AG G GR GSP K R ++ + A
Sbjct: 989 SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG-KGDRGENGSPGAPGAPG 1047
Query: 437 VPSGP----PKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRS---TAEIDAAD--G 487
P P P + +R E P P P P + A G T E AA G
Sbjct: 1048 HPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKG 1107
Query: 488 RRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVG----- 542
R P P A PG P P+ Q G GS GP G RGP G G
Sbjct: 1108 HRGFPGNPGA--PG-SPGPAGQQ-----GAIGSP--------GPAGPRGPVGPSGPPGKD 1151
Query: 543 ------GGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPA 596
G G + GE S S G G P A GG GA A A
Sbjct: 1152 GTSGHPGPIGPPGPRGNRGE-----RGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIA 1206
Query: 597 G 597
G
Sbjct: 1207 G 1207
Score = 62.0 bits (149), Expect = 2e-09
Identities = 143/539 (26%), Positives = 169/539 (31%), Gaps = 86/539 (15%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDA-SPSAPEVVGA 179
P G PP G G G G GP G PK GDA +P AP G
Sbjct: 625 PGGDKGDTGPP----GPQGLQGLPGTG--GPPGENGKPGEPGPK--GDAGAPGAPGGKGD 676
Query: 180 RAAV-----PRSFSAPYPTAG-GSAGPEACSSAERR-----ARAGPFLTPSPLHAVAMRS 228
A P AP G G GPE A A P L P + S
Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736
Query: 229 PRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGA-DGGPRRQNSVRQ 287
P P G D + GG G DG + RG P PG A G + +
Sbjct: 737 PGPKG----DKGEPGGPGA--DGVPG----KDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786
Query: 288 RPPDASP--SPGSARPAREPSLERVGGHPTS---PAALSRAWASSWESEAAPEPAAPPAA 342
P A P SPG P G P P A + E P A P
Sbjct: 787 LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG 846
Query: 343 PSPPDSPAEGRLVKAQY-IPGAQAAT-----RGLPGRAARR--KPPPLTRGRSVEQSPPR 394
S P P + VK + PG A RGLPG PP G + PP
Sbjct: 847 GSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPG 906
Query: 395 ER-----PRAAGRRGRMAEAS--GRRGSPRARKASRSQSETSLLGRASAVP-SGPPKYPT 446
P + G G +A G +GSP A+ + + G A +GPP P
Sbjct: 907 PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMP- 965
Query: 447 AEREEPRPPRPR--------------RGPA-----PTLAAQAAGSCRRWRSTAEIDAADG 487
R P P + RGP P LA A R + D G
Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS--DGLPG 1023
Query: 488 RRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGE 547
R P R G SP AP G G AG+ G G GPAG G
Sbjct: 1024 RDGSPGGKGDR--GENGSPGAPGAPGHPGPPGPVGP--AGKSGDRGESGPAGPAGAPGPA 1079
Query: 548 SESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASG--------GGAGAGAPAGP 598
A + P + G+ G+ + A G G G+ PAGP
Sbjct: 1080 GSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP 1138
Score = 60.8 bits (146), Expect = 4e-09
Identities = 122/445 (27%), Positives = 144/445 (32%), Gaps = 82/445 (18%)
Query: 223 AVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQ 282
AV + P RPP G G P I R GQP + G+ G P
Sbjct: 86 AVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPG--RNGDPGIPGQPGSP--GSPGPPGIC 141
Query: 283 NSVRQRPPDASPS------------------PGSARPAREPSLERVGGHPTSPAALSRAW 324
S P + SP PG A P P GHP SP +
Sbjct: 142 ESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG 201
Query: 325 ASSWESEAAPE-PAAPPAAPSP------------PDSPAEGRLVKAQYIPGAQAATRGLP 371
+A P P PP A P P P E L I G A G P
Sbjct: 202 PPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKG-PAGIPGFP 260
Query: 372 GRAARR--------KPPPLTRGRSVEQSPPRER-------PRAA-GRRGR--MAEASGRR 413
G R K G E P E PR A G RGR + A+G R
Sbjct: 261 GMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGAR 320
Query: 414 GSPRARKASRSQSETSLLGRA----------SAVPSGPPKYPTA--EREEPRPP--RPRR 459
G+ AR + G A P+G P A +R EP P +
Sbjct: 321 GNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQ 380
Query: 460 GPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAG 519
GP + + A I A G + R P PGP + AP R G AG
Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGAPG-LMGARGP----PGPAGANGAPGLR---GGAG 432
Query: 520 SDSECSA-GRLGPLGRRGPAG--GVGGGYGESESSASEGESPAFS-SASSDSDGSGGLVW 575
+ A G GP G RG AG GV G GE S GE A ++ G+ G
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRG 492
Query: 576 P--QQLVAATAASGGGAGAGAPAGP 598
P + G GA PAGP
Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGP 517
Score = 59.3 bits (142), Expect = 1e-08
Identities = 141/604 (23%), Positives = 187/604 (30%), Gaps = 84/604 (13%)
Query: 50 PGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEA--------------LPGLVWDLGQ 95
PGM G D + ++ E A + L + A PGL G
Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319
Query: 96 QLGDLSLESGGLEQESGR--SSGFYEDPSSTG--GPDSPPST--FCGDSGFSGSSSY-GR 148
+ D + S G G ++GF P + G GP P + G G G + G
Sbjct: 320 RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGA 379
Query: 149 LGPSEPRGIYASERPKS-LGDAS-PSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSA 206
GP P GI S K +G A P AP ++GAR P AG + P A
Sbjct: 380 QGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG--------PPGPAGANGAPGLRGGA 431
Query: 207 ERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAG 266
+ G P P R P + G G P + + L RGA
Sbjct: 432 GEPGKNGAKGEPGPR---GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP 488
Query: 267 QPRTSPGGADGGPRRQNSVRQR--PPDASPSPGSARPARE-----PSLERVGGHPTSPAA 319
R P G +G P + +R P A P + P R+ P + + G P P +
Sbjct: 489 GFR-GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547
Query: 320 LSRAWASSWESEAA----PEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAA 375
+ + E+ P P+ P P P K + RG PG
Sbjct: 548 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGP----KGNDGAPGKNGERGGPGGPG 603
Query: 376 RRKPPPLTRGRSVEQSPPRER-----------PRAAGRRGRMAEA-----SGRRGSPRAR 419
+ PP G + Q PP P G +G +G+ G P +
Sbjct: 604 PQGPPG-KNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662
Query: 420 KASRSQSETSLLGRASAVPS-GPPKYPTAE--REEPRPPRPRRGPAPTLAAQAAGSCRRW 476
+ + G A A GPP A R PP P G G+
Sbjct: 663 GDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA--- 719
Query: 477 RSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRG 536
T + G R PGP P G G D G GP G G
Sbjct: 720 -GTPGLQGMPGER-----GGLGSPGPKGDKGEPGGPGADGVPGKD-----GPRGPTGPIG 768
Query: 537 PAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPA 596
P G G + E A A S G G P A +G G G
Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828
Query: 597 GPAK 600
P +
Sbjct: 829 APGE 832
Score = 54.7 bits (130), Expect = 3e-07
Identities = 120/477 (25%), Positives = 145/477 (30%), Gaps = 112/477 (23%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDASPSAPE-VVG 178
P G P +P G+ G G + G G P G+ P G A P P+ V G
Sbjct: 806 PGPAGFPGAPGQN--GEPGGKGERGAPGEKGEGGPPGVAGP--PGGSGPAGPPGPQGVKG 861
Query: 179 ARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTD 238
R + +A +P A G GP + P P P P G P D
Sbjct: 862 ERGSPGGPGAAGFPGARGLPGPPGSNG-----------NPGP--------PGPSGSPGKD 902
Query: 239 SPD--AGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSP 296
P AG G P G P S D G P SP
Sbjct: 903 GPPGPAGNTGAP-----------------GSPGVSGPKGDAGQ----------PGEKGSP 935
Query: 297 GSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVK 356
G+ P P +P L A + A A PP P P SP +
Sbjct: 936 GAQGP------------PGAPGPLGIAGITG-----ARGLAGPPGMPGPRGSPGPQGVKG 978
Query: 357 AQYIPGAQAAT--------RGLPGRAARRKPPPLTRGRSVEQSPPRE-RPRAAGRRGRMA 407
PGA + +GLPG A P + P R+ P G RG
Sbjct: 979 ESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG 1038
Query: 408 E-----ASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPA 462
A G G P + + G A P+G P P R P P PR
Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG--PAGAPG-PAGSRGAPGPQGPRGDKG 1095
Query: 463 PTLAAQAAGSCRRWRSTAEIDAADGRR--------------VRPRAPAARVPGPG----- 503
T AAG + R A G PR P PG
Sbjct: 1096 ETGERGAAG-IKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTS 1154
Query: 504 --PSPSAPQR-RLLYGCAGSD-SECSAGRLGPLGRRGPAGGVGGGYGESESSASEGE 556
P P P R G GS+ S G+ GP G G G GG G + + GE
Sbjct: 1155 GHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGE 1211
Score = 30.8 bits (68), Expect = 3.9
Identities = 42/154 (27%), Positives = 52/154 (33%), Gaps = 30/154 (19%)
Query: 432 GRASAVPSGPPKYPT---------AEREEPRPPR-PRRGPAPTLAAQAA--------GSC 473
G AV PP PT + +P PP P R P + Q G C
Sbjct: 82 GECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGIC 141
Query: 474 RRWRS-----TAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGR 528
+ + + D+ D + A PGP P P G GS S G
Sbjct: 142 ESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG--SPGY 199
Query: 529 LGPLGRRGPAG-----GVGGGYGESESSASEGES 557
GP G G AG G G G S + +GES
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGES 233
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 65.9 bits (159), Expect = 1e-10
Identities = 90/342 (26%), Positives = 118/342 (34%), Gaps = 85/342 (24%)
Query: 242 AGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPP----DASPSPG 297
AGG P G R R G+PR + GG G R + R R + PG
Sbjct: 5 AGGGSCPGPG-------SARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPG 57
Query: 298 SARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPS----PPDSPAEGR 353
A P + +L R+ G L R WA PS P + ++G
Sbjct: 58 GAEPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGE 117
Query: 354 LVKAQY---------IPGA-QAATRGLPGRAARRK-------PPPLTRGRSVEQSPPRER 396
+ ++ P + ++A R GRA R + P P R V +PP+
Sbjct: 118 SDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTP 177
Query: 397 PRAAGRRG--RMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRP 454
R G G RM +A T LL RA A P+ P + EP
Sbjct: 178 ARKRGEEGTERMVQAL-----------------TELLRRAQA-----PQAPRSRACEPST 215
Query: 455 PRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVP------------GP 502
PR RG P + AG CRR + + A +P P VP GP
Sbjct: 216 PRRSRGRPP---GRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGP 272
Query: 503 GPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGG 544
GP P P+R G+ GR G G GGG
Sbjct: 273 GPGPGTPRR--------------GGQSSRGGRGGRGRGRGGG 300
Score = 48.5 bits (114), Expect = 2e-05
Identities = 127/524 (24%), Positives = 164/524 (31%), Gaps = 120/524 (22%)
Query: 108 EQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLG 167
E+E+ R+ P T P PST G GP E A + L
Sbjct: 481 EREAARAG-----PEGTSPPTPTPSTATG-------------GPPEDSPTVAPKSTTFLK 522
Query: 168 DASPSAPEVVGARAA----VPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHA 223
+ VV AR++ PR F P E P +T SP
Sbjct: 523 NIRQFIMPVVSARSSRVIKTPRRFM--------DEDPPKPPKVEVSPVLRPPITTSP--- 571
Query: 224 VAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQN 283
+ P P PP +P PL ++LR R R P P
Sbjct: 572 PVPQEPAPVPSPPR-APTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPP--- 627
Query: 284 SVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAP 343
PP SP P A +R P L R S A L +ES P P P AP
Sbjct: 628 -----PPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK-----IYESVLTPPPLGAPEAP 677
Query: 344 SP-----PDSPAE------GRL---------------VKAQYIP-GAQAATRGLPGRAAR 376
P DSPAE GR VKA+ P GA A + G +A
Sbjct: 678 EPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL 737
Query: 377 RKP-----------------PPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRAR 419
+P P L S +Q PP E+ R AG G + +
Sbjct: 738 LQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAG-VGSLPLSGVEEKMFSLL 796
Query: 420 KASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRST 479
K ++ Q + V + P P + EE +A R
Sbjct: 797 KRAKVQLFKIDQQQQQKVAASMPLSPGGQMEE-------------VAGAVKQISDRGPVR 843
Query: 480 AEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAG 539
+E ++ + +R RP P + V GP + G A + RL L R
Sbjct: 844 SEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQD 903
Query: 540 GVGGGYGESESSASEGES-----------PAFSSASSDSDGSGG 572
E SSASE ES A S+ GSGG
Sbjct: 904 LA----TEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGG 943
Score = 45.8 bits (107), Expect = 1e-04
Identities = 70/266 (26%), Positives = 87/266 (32%), Gaps = 64/266 (24%)
Query: 289 PPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDS 348
PP P+P P PS P P P P +PP PSPP
Sbjct: 404 PPLTPPAPSPPPPLPPPSTS-----PPPPLC-----------PPPPPPVSPPPLPSPPPP 447
Query: 349 PAEGRLVKA--QYIPGAQAATRGLP---------GRAARRKP----PPLTRGRSVEQSPP 393
PA+ ++ +P + RG P AAR P PP + PP
Sbjct: 448 PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPP 507
Query: 394 RERPRAAG---------RRGRMAEASGRRGSPRARKASR----------SQSETSLLGRA 434
+ P A R+ M S R S R K R + E S + R
Sbjct: 508 EDSPTVAPKSTTFLKNIRQFIMPVVSAR--SSRVIKTPRRFMDEDPPKPPKVEVSPVLRP 565
Query: 435 SAVPSGP-PKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCR----RWRS-TAEIDAADGR 488
S P P+ P PR P P P P L + R RW S T E+
Sbjct: 566 PITTSPPVPQEPAPVPSPPRAPTPPSTPVP-LPEKRRSILREPTFRWTSLTRELPPPP-- 622
Query: 489 RVRPRAPAARVPGPGPSPSAPQRRLL 514
P P P P P+P+ RR L
Sbjct: 623 ---PAPPPPPAPSPPPAPATSSRRPL 645
Score = 38.9 bits (89), Expect = 0.014
Identities = 49/204 (24%), Positives = 67/204 (32%), Gaps = 29/204 (14%)
Query: 260 RRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAA 319
+RR G+GQ GG+ +++ + + + E ER PAA
Sbjct: 341 QRRVGSGQ-----GGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKE-ERAVAEEMMPAA 394
Query: 320 LSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKP 379
E++ P P PPA PP P P P P
Sbjct: 395 EKE------EAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPP----LPSP 444
Query: 380 PPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPS 439
PP E+SPP P A S +RG P + R++ E + RA +
Sbjct: 445 PPPPAQEEQEESPPPVVP---------ATCSRKRGRPPLTPSQRAEREAA---RAGPEGT 492
Query: 440 GPPKYPTAEREEPRPPRPRRGPAP 463
PP PT PP AP
Sbjct: 493 SPPT-PTPSTATGGPPEDSPTVAP 515
Score = 36.2 bits (82), Expect = 0.094
Identities = 94/374 (25%), Positives = 118/374 (31%), Gaps = 60/374 (16%)
Query: 162 RPKSLGDASPSAPEVV-GARAAVPRSFSAPYPTAGGSAGP-EACSSAERRARAGPFLTPS 219
RP S G A P AP GAR VP + P G S GP + S P +
Sbjct: 1846 RPDS-GSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDP 1904
Query: 220 PLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGP 279
A RS RP P P + A PL + + Q R P +
Sbjct: 1905 DFPAPPRRSRRPSPLAPR-PPPSRWASPPL-------------KTSPQLRVPPPTSVVTA 1950
Query: 280 RRQNSVRQRPPDASPSPGSARPARE--PSLERVGGHPTSPA--ALSRAWASSWESEAAPE 335
S PP +PSP +E V G + A S ++ E
Sbjct: 1951 LTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAA 2010
Query: 336 PAAPPAAPSPPDSPAEGRLVKAQYI---------PG-AQAATRGLP----------GRAA 375
A + P DS E ++YI PG A +AT G P G +
Sbjct: 2011 GAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDS 2070
Query: 376 RRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRAS 435
+ RG+ S P R G + A R P + LG
Sbjct: 2071 EAEAVQQPRGQGTPPSGP-----GVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLG--- 2122
Query: 436 AVPSGPPKYPTAEREEPRPPRPRRG----PAPTLAAQAAGSCRRWRSTAEIDAADGRRVR 491
GP REE PP P P+ L A A R + A + A G RV
Sbjct: 2123 ----GPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTF---AWLPGAPGVRVL 2175
Query: 492 PRAPAARVPGPGPS 505
PA P P S
Sbjct: 2176 SLGPAPEPPKPATS 2189
Score = 32.0 bits (71), Expect = 1.8
Identities = 58/234 (24%), Positives = 78/234 (33%), Gaps = 39/234 (16%)
Query: 223 AVAMRSPRPCGRPPTDSP--------DAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGG 274
A A++ PR G PP+ AG RP + S ++ + G PG
Sbjct: 2072 AEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGG-----PGD 2126
Query: 275 ADGGPRRQNSVRQRPPDAS---PSPGSARPAREPS-------------LERVGGHP---- 314
GPR + S+ PP A+ PS G +P+ + +G P
Sbjct: 2127 GGAGPREE-SLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPK 2185
Query: 315 --TSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYI--PGAQAATRGL 370
TS L + A PP PP P + PG +
Sbjct: 2186 PATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPV 2245
Query: 371 PGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRR-GSPRARKASR 423
G PPP V S P PR A R R++ SGR +P KA R
Sbjct: 2246 VGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPR 2299
Score = 29.6 bits (65), Expect = 8.8
Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 12/71 (16%)
Query: 530 GPLGRRGPAGGVGGGYG-------ESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAA 582
GP +RG G G G+G E ESS E + F SD D V P L +A
Sbjct: 86 GPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDED-----VAPSSLRSA 140
Query: 583 TAASGGGAGAG 593
+ G A G
Sbjct: 141 LRSQRGRAPRG 151
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 65.5 bits (158), Expect = 1e-10
Identities = 125/488 (25%), Positives = 162/488 (33%), Gaps = 81/488 (16%)
Query: 54 GAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGG------L 107
G++ DE + + D +LE QL A L + ++ + G +
Sbjct: 4 GSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVV 63
Query: 108 EQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIY--------- 158
++G + G P + P G R GP PR
Sbjct: 64 SGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123
Query: 159 ASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTP 218
A RP G A AP V A AAV + P P G A P A ARAGP P
Sbjct: 124 AKLRPPPEGSAGSCAP--VPAAAAVA---AGPEPAPAGPAKP--AGPAALAARAGP--GP 174
Query: 219 SPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGG 278
P P P P P GA + L+G +ALL A P S
Sbjct: 175 GP-------GPGPGPGPGPGKPAGPGAAQTLNGS-AALLNSHH---AAAPAVS------- 216
Query: 279 PRRQNSVRQRPPDASPSPGSARPAREPSLERVGGH--PTSPAALSRAWASSWESEAAPEP 336
V P P P A P G P +PAA S AAP P
Sbjct: 217 -----LVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS--------PPAAPAP 263
Query: 337 AAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRER 396
AAP AAP PP PA L + PG A G P A PP + + P
Sbjct: 264 AAPAAAP-PPPPPAPATLARP---PGHPA---GPPTAAPAVPPPAAAQNGGSAGAAPAPA 316
Query: 397 PRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRA-----SAVPSGPPKY------- 444
P A G G + + +++S ++ A + SGP
Sbjct: 317 PAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376
Query: 445 PTAEREEPRP---PRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRR--VRPRAPAARV 499
PT + P P P P G L AAG+ + S G R + P A R+
Sbjct: 377 PTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRL 436
Query: 500 PGPGPSPS 507
P P +P+
Sbjct: 437 PQPPQNPT 444
Score = 46.6 bits (109), Expect = 7e-05
Identities = 85/333 (25%), Positives = 108/333 (32%), Gaps = 58/333 (17%)
Query: 264 GAGQPRTSPGGADGGPRRQNSVRQRPPDASPS-PGSARPAREPSLERVGGHPTSPAALSR 322
GAG + G P + R RP P PG P R V P PAA R
Sbjct: 72 GAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRP----LVPAGPAPPAAKLR 127
Query: 323 AWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPL 382
AP PAA A P +PA A+ A A R PG P P
Sbjct: 128 PPPEGSAGSCAPVPAAAAVAAGPEPAPAG----PAKPAGPAALAARAGPGPGPGPGPGP- 182
Query: 383 TRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPP 442
P +P G + ++ S A + S G A+ +P P
Sbjct: 183 --------GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNN---GPAALLPLPKP 231
Query: 443 KYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGP 502
P + P PAP + A P APAA P P
Sbjct: 232 AAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA------------------PAAPAAAPPPP 273
Query: 503 GPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSS 562
P+P+ R + AG + +A + P PA GG S G +PA +
Sbjct: 274 PPAPATLARPPGHP-AGPPT--AAPAVPP-----PAAAQNGG--------SAGAAPAPAP 317
Query: 563 ASSDSDGSGGLVWPQQLVAATAASGGGAGAGAP 595
A+ G G P AA AA G A +P
Sbjct: 318 AAGGPAGVSGQPGPG---AAAAAPAPGVKAESP 347
Score = 39.3 bits (90), Expect = 0.011
Identities = 74/300 (24%), Positives = 100/300 (33%), Gaps = 49/300 (16%)
Query: 310 VGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRG 369
+G H S + A A AAP AP AAP PP A R
Sbjct: 58 LGNHVVSGSPAGAAGAGP----AAPAEGAPGAAPEPPP------------------AGRA 95
Query: 370 LPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETS 429
PG ++P P + R + + P P AA R ++G A A + E +
Sbjct: 96 RPGGGGPQRPGPPSPRRPLVPAGPA--PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA 153
Query: 430 LLGRASAVPSGPPKYPTAEREEPRP-PRPRRGPAPTLAAQAAGSCRRWRSTAEI-----D 483
G A P+GP P P P P GP P A G+ + +A +
Sbjct: 154 PAGPAK--PAGPAALAARAGPGPGPGPGPGPGPGPGKPA-GPGAAQTLNGSAALLNSHHA 210
Query: 484 AADGRRVRPRAPAARVPGPGPSPSAP----QRRLLYGCAGSDSECSAGRLGPLGRRGPAG 539
AA + PAA +P P P+AP Q G A + + P PA
Sbjct: 211 AAPAVSLVNNGPAALLPLP--KPAAPGTVIQTPPFVGAAAPPAPAAPS---PPAAPAPAA 265
Query: 540 GVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPA 599
+ A+ P + + P A A +GG AGA PA
Sbjct: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAA-------PAVPPPAAAQNGGSAGAAPAPAPA 318
Score = 34.7 bits (78), Expect = 0.27
Identities = 55/221 (24%), Positives = 67/221 (30%), Gaps = 91/221 (41%)
Query: 393 PRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPP----KYPTAE 448
P R AAG G + G+ A A+ ++ G A P PP +
Sbjct: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAE------GAPGAAPEPPPAGRARPGGGG 101
Query: 449 REEPRPPRPRR-----GPAPTLAAQ------AAGSCRRWRSTAEIDAADGRRVRPRAPAA 497
+ P PP PRR GPAP A +AGSC A + AA AA
Sbjct: 102 PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSC------APVPAA----------AA 145
Query: 498 RVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGES 557
GP P+P+ P + AG R GP G G G
Sbjct: 146 VAAGPEPAPAGPAK-------------PAGPAALAARAGPGPGPGPG------------- 179
Query: 558 PAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGP 598
G G G G PAGP
Sbjct: 180 ----------------------------PGPGPGPGKPAGP 192
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 65.1 bits (157), Expect = 2e-10
Identities = 127/480 (26%), Positives = 172/480 (35%), Gaps = 64/480 (13%)
Query: 160 SERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTP- 218
S SL + PS P V R P P P G + P ++ E R P
Sbjct: 1580 SSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPR 1639
Query: 219 --SPLHAVAMRSPRPC---GRPPTDSPDAG--GAGRPLDGYISALLRRRRRRGAGQPRTS 271
P+ + R PR RP S + G AG + ++ R + GA T
Sbjct: 1640 RRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTW 1699
Query: 272 PGGADGGPRRQNSVRQRPPD--ASPSPGSA-RPAREPSLERVGGHPTSPAALSRAWASSW 328
A R +S + S GS +P + + G S + A+S
Sbjct: 1700 LHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASV 1759
Query: 329 ESEAAPEPAAPPAAP-----SPPDSPA--EGRLVKAQYIPGAQAATRGLPG-RAARRK-- 378
++ +P A P P + P PA GR V P +A +G PG RA RK
Sbjct: 1760 KTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVA 1819
Query: 379 PPPLTRGRSVEQ--SPPRERPRAAGRRGRMAEAS-----GRRGSPRARKASRSQSETSLL 431
PP L + + + SP ++R R+ R + +E + R +P AR A S +S
Sbjct: 1820 PPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQT 1879
Query: 432 GRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQA--AGSCRRWRSTAEIDAADGRR 489
AS P K P + P P P P A+ A + RS I
Sbjct: 1880 SPAS--QPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPA 1937
Query: 490 VRPRAPAAR-VPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGES 548
R P AR VP PGP G AG+++ A R G LG A + G S
Sbjct: 1938 RRGPPPLARAVPEPGPR----------GRAGTEAGPGA-RGGRLGLVRVASALSSG---S 1983
Query: 549 ESSASEG---------ESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPA 599
ESS G ESP S+ + AA+A G G PA PA
Sbjct: 1984 ESSDRSGFRRQLTFIKESPGLRRRRSELSSAES--------AASAPQGASPRRGRPALPA 2035
Score = 58.2 bits (139), Expect = 2e-08
Identities = 134/541 (24%), Positives = 183/541 (33%), Gaps = 113/541 (20%)
Query: 67 EDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQES----------GRSSG 116
++A A +AA A P L+ D LS + L + GR
Sbjct: 1546 KEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPA 1605
Query: 117 FYEDPSSTGGPDSPPSTFCGDSGFSG--SSSYGRLGP-------SEPRGIYASERP---- 163
+DP GG DS PS + SS+ R P +PR ERP
Sbjct: 1606 VTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGS 1665
Query: 164 -----KSLGDASPSAPEVV-------GARAAVPRSFSAPYPTAGGSAGPEACSSAERRAR 211
++ G S + V GA + V A T S+ ++ S
Sbjct: 1666 RERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGLS 1725
Query: 212 AGPFLTPSPLHAVAMRSPRPCG-------------------RPPTDSPDAGGAGRPLDGY 252
G L P P H ++ G R P G + G
Sbjct: 1726 VGSTLQP-PKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPG- 1783
Query: 253 ISALLRRRR--RRGAGQPRTSPGGADGGPRRQNSV------RQRPPDASPSPGSA----- 299
+ A+LR R + PR P G G V + P PSPG
Sbjct: 1784 VPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSL 1843
Query: 300 -RPAREPSLERVGGHP---TSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRL- 354
RPA+ L + P T PA L++ +SS S+ +P + P PP + A G L
Sbjct: 1844 HRPAKTSELATLSQPPRSATPPARLAKTPSSS-SSQTSP-ASQPLPRKRPPVTQAAGALP 1901
Query: 355 ---------VKAQYIPGAQAATRGLP------GRAARRKPPPLTRGRSVEQSPPRERPRA 399
A+ + Q T+ P R ARR PPPL R+V + PR R
Sbjct: 1902 GPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPL--ARAVPEPGPRGR--- 1956
Query: 400 AGRRGRMAEASGRRGSPRARKASRSQSETS----------LLGRASAVPSGPPKYPTAE- 448
AG GR G R A S SE+S + + + + +AE
Sbjct: 1957 AGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAES 2016
Query: 449 -REEPRPPRPRRG-PAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSP 506
P+ PRRG PA + C R+ A R+ R PAAR P PG P
Sbjct: 2017 AASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQ---RPPAAR-PSPGERP 2072
Query: 507 S 507
+
Sbjct: 2073 A 2073
Score = 49.7 bits (117), Expect = 8e-06
Identities = 106/420 (25%), Positives = 134/420 (31%), Gaps = 96/420 (22%)
Query: 174 PEVVGARAAVPRSFSAPYPTAGGSA----------GPEACSSAERRARAGPFLTPSPLHA 223
P V A A+P ++P P P +R AR GP P A
Sbjct: 1891 PPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGP-----PPLA 1945
Query: 224 VAMRSPRPCGRPPTDS-PDAGGAGRPLDGYISALL-------RRRRRRGAGQPRTSPGGA 275
A+ P P GR T++ P A G L SAL R RR + SPG
Sbjct: 1946 RAVPEPGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPG-- 2003
Query: 276 DGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE 335
RR+ S A+ +P A P R G P PA + + E AAP
Sbjct: 2004 ---LRRRRSELSSAESAASAPQGASPRR--------GRPALPAVFLCS-SRCEELRAAPR 2051
Query: 336 PAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRE 395
PA PP AAR P R+ +SP R
Sbjct: 2052 QGPAPARQRPP---------------------------AARPSPGERPARRTTSESPSRL 2084
Query: 396 RPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRAS-AVPSGPPKYPTAEREEPRP 454
RA R P K S S+ R AVP+ P A R
Sbjct: 2085 PVRAPAAR------------PETVKRYASLPHISVARRPDGAVPAAPASADAARRSSDGE 2132
Query: 455 PRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVP----GPGPSPSAPQ 510
PR P P +AA WR + D +R PA +P P +P+ P
Sbjct: 2133 PR----PLPRVAAPGT----TWRRIRDEDVP--HILRSTLPATALPLRGSTPEDAPAGPP 2182
Query: 511 RRLLYGCAGSDSECSAGRLG-----PLGRRGPAGGVGGGYGESESSASEGESPAFSSASS 565
R E +A + L R P G GG S +G S A + S+
Sbjct: 2183 PRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAGGQLSLLGSDVDGPSLAKAPISA 2242
Score = 45.8 bits (107), Expect = 1e-04
Identities = 129/513 (25%), Positives = 174/513 (33%), Gaps = 146/513 (28%)
Query: 106 GLEQESGRSSGFYED---PSS------TGGPDSPP--STFCGDSGFSGSSSYGRLGPSEP 154
GL Q+ SG ++D PSS TG P SP S F G S F + R P+
Sbjct: 766 GLAQDYASDSGCFDDDDAPSSLAAAAATGEPASPAALSLFLG-SPFLQGQALARTPPTR- 823
Query: 155 RGIYASERPKSLGDASPSAPEVVGARAAVPR-------------SFSAPYPTAGGSAGPE 201
RG +E+ S G+A+ +A AV R S + + G G E
Sbjct: 824 RGGKEAEKDTS-GEAAVAAKAKAKLALAVARIDQLVEDISALHTSSDDSFSLSSGDPGQE 882
Query: 202 A--------CSSA--------ERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGA 245
A CS E +RA P L HA S D+ +
Sbjct: 883 APREGRAQSCSPCRGPEGGRREAGSRAHPLLRLKAAHASL-------------SNDSLNS 929
Query: 246 GRPLDGY----------ISALLRRRRRRGAGQPRTS------PGGADGGPRRQNS---VR 286
G DGY ++AL RR GQPR S PG P R+ + R
Sbjct: 930 GSASDGYCPREHMLPCPLAALASRREDPRCGQPRPSRLDLDLPGCQAEPPAREATSADAR 989
Query: 287 QRPPDASPS-------PGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAP 339
R SP+ G++R EP + G SP A +AW + PE A
Sbjct: 990 VRTIKLSPTYQHVPLLEGASRAGAEP----LAGPGISPGARKQAWLPADHLSKVPEKLA- 1044
Query: 340 PAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRG---------RSVEQ 390
AAP S A +L AQ P + + L ++ +P P G +E+
Sbjct: 1045 -AAPLSVASKALQKLA-AQEGPLSLSRCSSLSSLSSAGRPGPSEGGDLDDSDSSLEGLEE 1102
Query: 391 SPPRERP-----RAAG-----------RRGRMAEASGRRGSPRARKASRSQSETSLLGR- 433
+ P E RA G RR R +P + + Q +L R
Sbjct: 1103 AGPSEAELDSTWRAPGATSLPVAIPAPRRNRGRGLGVEDATPSSSSENYVQETPLVLSRC 1162
Query: 434 --------------ASAVPSGP--------------PKYPTAEREEPRPPRPRRGPAPTL 465
AS++PS P P P R P PAP
Sbjct: 1163 SSVSSLGSFESPSIASSIPSEPCSGQGSGTISPSELPDSPGQTMPPSRSKTPPLAPAPQG 1222
Query: 466 AAQAAGSCRRWRSTAE--IDAADGRRVRPRAPA 496
+A +W S + +D AD R R R P+
Sbjct: 1223 PPEATQFSLQWESYVKRFLDIADCRE-RCRLPS 1254
Score = 44.3 bits (103), Expect = 3e-04
Identities = 87/383 (22%), Positives = 132/383 (34%), Gaps = 81/383 (21%)
Query: 119 EDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVG 178
ED S T + P F + S + G +P G +RP SA + +G
Sbjct: 1385 EDDSCTDSAEGTPVNFSSAASLSDETLQGP-PRDQPGGPAGRQRPTG---RPTSARQAMG 1440
Query: 179 ARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTD 238
R AGG+ S + RAG L P GRPP+
Sbjct: 1441 HRHK-----------AGGAGRSAEQSRGAGKNRAGLEL--------------PLGRPPSA 1475
Query: 239 SPDAGGAGRPLDGYISALLRRRRRRGAGQPR----TSPGGADGGPRRQNSVRQRPPDASP 294
D G+ + R RG G + T+P N + PP A+P
Sbjct: 1476 PADKDGS------------KPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAAAP 1523
Query: 295 SPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRL 354
+P R + P A +R + AP AAP A PP + + L
Sbjct: 1524 TPTHRRTS------------AIPRAFTRERPQGRKEAPAPSKAAPAA---PPPARTQPSL 1568
Query: 355 VKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRG 414
+ + P ++ ++ +P P PP PR GR + + G G
Sbjct: 1569 IADETPPCYSLSS----SASSLSEPEP--------SEPPAVHPR--GREPAVTKDPGPGG 1614
Query: 415 SPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAP---TLAAQAAG 471
+ + R+ E +SA+P P R +PR R PA +AAG
Sbjct: 1615 GRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAG 1674
Query: 472 SCRRWRSTAEIDAADGRRVRPRA 494
S R +++D+ + R ++ A
Sbjct: 1675 SDR----ASDLDSVEWRAIQEGA 1693
Score = 30.8 bits (68), Expect = 3.9
Identities = 69/240 (28%), Positives = 93/240 (38%), Gaps = 40/240 (16%)
Query: 148 RLGPSE-PRGIYASERPKSLGDASPSA-PEVVGARAAVPRSFSAPYPTAGGSAGPEACSS 205
R P E P SE P L +P+A PE V A++P A P A P A +
Sbjct: 2065 RPSPGERPARRTTSESPSRLPVRAPAARPETVKRYASLPHISVARRPDGAVPAAP-ASAD 2123
Query: 206 AERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGA 265
A RR+ G P PL VA +P R R D + +LR A
Sbjct: 2124 AARRSSDG---EPRPLPRVA--APGTTWR------------RIRDEDVPHILRSTLPATA 2166
Query: 266 GQPR-TSPGGADGGP---RRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALS 321
R ++P A GP + ++V Q A+P S + PSLE P +PA
Sbjct: 2167 LPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNS---STSPSLE-TREPPGAPAGGQ 2222
Query: 322 RAWASSWESEAAPEPAAPPAAPSPPDSP--AEGRLVKAQYIPGAQAATRGLPGRAARRKP 379
+ S + P A +P +P EG V + G A+ G P R+AR P
Sbjct: 2223 LSLLGS-------DVDGPSLAKAPISAPFVHEGLGVA---VGGFPASRHGSPSRSARVPP 2272
Score = 30.4 bits (67), Expect = 5.1
Identities = 31/115 (26%), Positives = 44/115 (38%), Gaps = 16/115 (13%)
Query: 305 PSLERVGGHPTSPA----ALSRAWASS---WESEAAPEPAAPPAAPSPPDSPAEGRLVKA 357
P+ E P P L++ +AS ++ + AP A AA P SPA L
Sbjct: 748 PAAEAATKKPLPPLRHLDGLAQDYASDSGCFDDDDAPSSLAAAAATGEPASPAALSLFLG 807
Query: 358 QYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGR 412
L G+A R PP G+ E+ E AA + ++A A R
Sbjct: 808 SPF---------LQGQALARTPPTRRGGKEAEKDTSGEAAVAAKAKAKLALAVAR 853
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 64.7 bits (156), Expect = 2e-10
Identities = 131/529 (24%), Positives = 166/529 (31%), Gaps = 78/529 (14%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSL--GDASPSAPEVV 177
P + GP PP G+ G G + G GPS P G+ + G P +
Sbjct: 605 PIGSRGPSGPPGPD-GNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLR 663
Query: 178 GARAAVPRSFSAPYPTAGGSAGPEACSSAERRA-RAGPFLTPSPLHAVAMRSPRPCGRPP 236
G R + P A G+ GP + A AGP P + R P
Sbjct: 664 GEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPN 723
Query: 237 TDSPDAGGAGRPLDGYISALLRRRRRRGAGQPR--------TSPGGADG-----GPRRQN 283
+ AG AG+P + RGA P+ T P GA G GP
Sbjct: 724 GFAGPAGAAGQP---------GAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPA 774
Query: 284 SVRQR--PPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE------ 335
R PP + PG+A P + G P P + + P
Sbjct: 775 GSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEV 834
Query: 336 -------------PAAPPAAPSPPDSPAEGRLVKAQYIPGAQAAT--RGLPGRA-ARRKP 379
P+ PP +P L+ A I G + RGLPG A A +P
Sbjct: 835 GAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEP 894
Query: 380 PPL-TRGRSVEQSPP--------RERPRAAGRRGRMAEAS--GRRGSPRARKASRSQSET 428
PL G + PP P AGR G GR G P +
Sbjct: 895 GPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNI 954
Query: 429 SLLGRASAV-PSGP--PKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAA 485
+G A A P GP P R E P P GPA + + + R
Sbjct: 955 GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPV-GPAGAVGPRGPSGPQGIRGDKGEPGE 1013
Query: 486 DGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSA-GRLGPLGRRGPAGGVGGG 544
G R P + G P G AG + A G +GP G RGPAG G
Sbjct: 1014 KGPRGLPG-----LKGHNGLQGLP------GIAGHHGDQGAPGSVGPAGPRGPAGPSGPA 1062
Query: 545 YGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAG 593
+ + PA G G P SGGG G
Sbjct: 1063 GKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFG 1111
Score = 64.3 bits (155), Expect = 3e-10
Identities = 140/546 (25%), Positives = 188/546 (34%), Gaps = 79/546 (14%)
Query: 106 GLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKS 165
GL+ + G + G +P + G +P T G G G GR+G P G S+ S
Sbjct: 187 GLKGQPG-APGVKGEPGAPGENGTPGQT--GARGLPGER--GRVGAPGPAGARGSDG--S 239
Query: 166 LGDASPSAPEVVGARAAVPRSFSAPYPT----AGGSAGPEACSSAERRAR----AGPFLT 217
+G P+ P +G+ A P AP P A G+AGP + +GP
Sbjct: 240 VGPVGPAGP--IGS-AGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGP 296
Query: 218 PSPLHAVAMRSPRPCGRPPTDSPDAGGAG-RPLDGYISALLRRRRRRGAGQPRTSPGGAD 276
P A + + P + G G R + G + A R G+P P G+
Sbjct: 297 PGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEP--GPAGSK 354
Query: 277 GGPRRQNSVRQRPPDASPSP-------------GSARPAREPSLERVGGHPTSPAALSRA 323
G + P P P GSA P P L G P A RA
Sbjct: 355 GESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRA 414
Query: 324 WASSWE-SEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGA--------QAATRGLPGRA 374
S A PA P E L+ + +PG+ + GLPG
Sbjct: 415 GVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGID 474
Query: 375 ARRKP--PPLTRGR--SVEQSPPRERPRAAGRRGRMAEA--SGRRGSPRARKASRSQSET 428
R P P RG ++ P+ G+ G A +G RG+P + +Q
Sbjct: 475 GRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP 534
Query: 429 SLLG----RASAVPSGPPKY-----PTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRST 479
G + P GPP + P+ E P RG R R
Sbjct: 535 GPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPG-ERGLHGEFGLPGPAGPRGERGP 593
Query: 480 AEIDAADGRR--VRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGP 537
A G + R P+ PGP + P + G G+ AG GP G G
Sbjct: 594 PGESGAAGPTGPIGSRGPSGP-PGPDGNKGEPG---VVGAVGT-----AGPSGPSGLPGE 644
Query: 538 AG--GVGGGYGESESSASEGE--SPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAG 593
G G+ GG GE GE +P A + G+ G P A G AGA
Sbjct: 645 RGAAGIPGGKGEKGEPGLRGEIGNPGRDGARG-APGAVGAPGP----AGATGDRGEAGAA 699
Query: 594 APAGPA 599
PAGPA
Sbjct: 700 GPAGPA 705
Score = 53.5 bits (127), Expect = 6e-07
Identities = 74/285 (25%), Positives = 91/285 (31%), Gaps = 52/285 (18%)
Query: 336 PAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRE 395
P PP P PP P G AQY G+ P P+ PR
Sbjct: 58 PTGPPGPPGPPGPPGLGGNFAAQY-----------DGKGVGLGPGPM------GLMGPRG 100
Query: 396 RPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASA-VPSGPPKYPTAEREEPRP 454
P AAG G G G P E G A A P+GPP + +P
Sbjct: 101 PPGAAGAPGPQG-FQGPAGEP---------GEPGQTGPAGARGPAGPPGKAGEDGHPGKP 150
Query: 455 PRPRR----GPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAAR----VPGPGPSP 506
RP GP ++ + DG + +P AP + PG +P
Sbjct: 151 GRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTP 210
Query: 507 SAPQRRLL------------YGCAGSDSECS-AGRLGPLGRRGPAG--GVGGGYGESESS 551
R L G GSD G GP+G GP G G G GE +
Sbjct: 211 GQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAV 270
Query: 552 ASEGES-PAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAP 595
+ G + PA G G V P A +G AG P
Sbjct: 271 GNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLP 315
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 64.3 bits (155), Expect = 3e-10
Identities = 70/268 (26%), Positives = 95/268 (35%), Gaps = 56/268 (20%)
Query: 258 RRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSP 317
RR+ R + + R+SP + S R R SPSP + + P L P
Sbjct: 174 RRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEP 233
Query: 318 AALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARR 377
+ S PEP P PSP + + + + TR P +R
Sbjct: 234 SVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK---------EKEKTR--PRSRSRS 282
Query: 378 KPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAV 437
K TR RS + PR R R+ R + + RR SPR R +
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSR----SYSPRRRPSPRRRPS---------------- 322
Query: 438 PSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADG------RRVR 491
P+ T R P PPR RR +P RR RS+A + + R
Sbjct: 323 ----PRRRTPPRRMPPPPRHRRSRSPVR--------RRRRSSASLSGSSSSSSSSRSRSP 370
Query: 492 PRAPAARVPGP-------GPSPSAPQRR 512
P+ P R P PS S P+RR
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRR 398
Score = 57.0 bits (136), Expect = 5e-08
Identities = 100/429 (23%), Positives = 143/429 (33%), Gaps = 48/429 (11%)
Query: 138 SGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGS 197
S S SSS R P +P S P+ SPSA R P + P P S
Sbjct: 358 SSSSSSSSRSRSPPKKPPK-RTSSPPRKTRRLSPSASPP--RRRHRPSPPATPPPKTRHS 414
Query: 198 AGPEACSSAER-RARAGPFLTPSPLH----AVAMRSPRPCGRP-----PTDSPDAGGAGR 247
P+ + + R P T + SP P +P D GG
Sbjct: 415 PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474
Query: 248 PLDGYISALLRRRRRRGAGQPRTSPGGA-----DGGPRRQNSV-------RQRPPD--AS 293
D ++ +RR+ R Q +S G+ D P+R + R+ P AS
Sbjct: 475 AAD----SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530
Query: 294 PSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGR 353
PSP + P R P R+ + + P PP +P P
Sbjct: 531 PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS 590
Query: 354 LVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRR 413
+Y P Q P R PP R SPP + RR + +R
Sbjct: 591 PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK------RRVSHSPPPKQR 644
Query: 414 GSPRARKASRSQSETSLLGRASAVPSGPPKYPTAERE---EPRPPRPRRGPAPTLAAQAA 470
SP ++ S S S G + + + + P + PRP P+ +P + A
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
Query: 471 GSCRRWRSTAEIDAADGRRV-RPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRL 529
S + R + RRV R P PSP + +R S S +G
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-------VSSSRSVSGSP 757
Query: 530 GPLGRRGPA 538
P ++ PA
Sbjct: 758 EPAAKKPPA 766
Score = 54.3 bits (129), Expect = 3e-07
Identities = 75/307 (24%), Positives = 95/307 (30%), Gaps = 53/307 (17%)
Query: 233 GRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQP----RTSPGGADGGPRRQNSVRQR 288
GR SP + P R RRRR P R SP A PRR+ +
Sbjct: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPP-PRRRRTPTPP 576
Query: 289 PPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPP---AAPSP 345
P +PSP R R PS R SP R S P PP A+PSP
Sbjct: 577 PRRRTPSPPPRR--RSPSPRRY-----SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP 629
Query: 346 PD---------------------SPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTR 384
P SP+ + P P R P P R
Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689
Query: 385 GRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKY 444
SPP R A+ R S + R+ SR+ + AS P +
Sbjct: 690 APQTSSSPPPVRRGASSSPQRRQSPSP--STRPIRRVSRTPEPKKIKKAASPSPQSVRRV 747
Query: 445 PTAEREEPRP-PRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPG 503
++ P P ++ PAP Q+ W P P + P
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWS--------------PAVPVKKAKSPT 793
Query: 504 PSPSAPQ 510
PSPS P+
Sbjct: 794 PSPSPPR 800
Score = 51.2 bits (121), Expect = 3e-06
Identities = 95/405 (23%), Positives = 136/405 (33%), Gaps = 78/405 (19%)
Query: 109 QESGRSSGFYEDPSSTGGPDSPPSTFC---GDSGFSGSSSYGRLGPSEPRGIYASERPKS 165
Q+S SG SS+ D P G+ G S R PR P+
Sbjct: 490 QQSSSDSG-----SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG 544
Query: 166 LGDASPSAPEVVGARAAVP------RSFSAPYPTAGGSAGPEACSSAERRARAGPFL--- 216
SPS P R+ P R P P + P S R + P
Sbjct: 545 RRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY 604
Query: 217 --TPSPLHAVAMRSPRPCGR-----PP----TDSPDAGGAGRPLDGYISALLRRRRRRGA 265
+P P A P P R PP + SP P+ S L + R+G+
Sbjct: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS 664
Query: 266 GQPRTSPGGADGGPRRQNSVRQRP--PDASPSP------GSARPAREPS-------LERV 310
R++ P +++S RP P S SP S+ P R S + RV
Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRV 724
Query: 311 GGHP--------TSPAALS-RAWASSWESEAAPEPAA--PPAAPSPPDSPAEGRLVKAQY 359
P SP+ S R +SS +PEPAA PPA PSP S +
Sbjct: 725 SRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS--------- 775
Query: 360 IPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRAR 419
+T P ++ P + SPPR + G + + + + +
Sbjct: 776 -----PSTNWSPAVPVKKAKSP-----TPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKH 825
Query: 420 KASRSQSETSLLGRASAVPSGPPKY----PTAEREEP-RPPRPRR 459
K + + + A+A P T +EEP P P++
Sbjct: 826 KKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKK 870
Score = 32.3 bits (72), Expect = 1.4
Identities = 21/61 (34%), Positives = 27/61 (44%)
Query: 394 RERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPR 453
RER R+ RR + + RR SP R+ RS S + S PS P+ E P
Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE 225
Query: 454 P 454
P
Sbjct: 226 P 226
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.8 bits (151), Expect = 9e-10
Identities = 104/413 (25%), Positives = 142/413 (34%), Gaps = 83/413 (20%)
Query: 125 GGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLG------DASPSAPEVV- 177
GG F G G G S+G GP G++ + PK D+ S P ++
Sbjct: 71 GGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLP 130
Query: 178 -GARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPP 236
G R+ + FS P +GP G F PSP H P+ R P
Sbjct: 131 PGGRSTSAKPFSPP-------SGP------------GRFPVPSPGHRSGPPEPQR-NRMP 170
Query: 237 TDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSP 296
PD G + + + R + + R SP GGPR Q S PP P P
Sbjct: 171 PPRPDVGSKPDSIPPPVPST--PRPIQSSPHNRGSPP-VPGGPR-QPSPGPTPP---PFP 223
Query: 297 GSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAA----PSPPDSPAEG 352
G+ A +GG + LS +SS S P P P A P PP P
Sbjct: 224 GNRGTA-------LGGGSIRQSPLS---SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGN 273
Query: 353 RLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGR 412
R P R A PPP V +P RP A+ + R
Sbjct: 274 R-------PSIH--------REAVPPPPPQNNKPPVPSTP---RPSASSQAPPPPPPPSR 315
Query: 413 RGSPRARKASRSQSETSLLGRAS-AVPSGPPKYPTAEREEPRPPRPRRGPAPTL------ 465
G P +S ET L + + ++ S P P+ R P PP P P P +
Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGR 375
Query: 466 ---------AAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAP 509
++ + R +T ++ + G P +P PS AP
Sbjct: 376 SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.8 bits (151), Expect = 9e-10
Identities = 104/413 (25%), Positives = 142/413 (34%), Gaps = 83/413 (20%)
Query: 125 GGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLG------DASPSAPEVV- 177
GG F G G G S+G GP G++ + PK D+ S P ++
Sbjct: 71 GGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLP 130
Query: 178 -GARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPP 236
G R+ + FS P +GP G F PSP H P+ R P
Sbjct: 131 PGGRSTSAKPFSPP-------SGP------------GRFPVPSPGHRSGPPEPQR-NRMP 170
Query: 237 TDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSP 296
PD G + + + R + + R SP GGPR Q S PP P P
Sbjct: 171 PPRPDVGSKPDSIPPPVPST--PRPIQSSPHNRGSPP-VPGGPR-QPSPGPTPP---PFP 223
Query: 297 GSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAA----PSPPDSPAEG 352
G+ A +GG + LS +SS S P P P A P PP P
Sbjct: 224 GNRGTA-------LGGGSIRQSPLS---SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGN 273
Query: 353 RLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGR 412
R P R A PPP V +P RP A+ + R
Sbjct: 274 R-------PSIH--------REAVPPPPPQNNKPPVPSTP---RPSASSQAPPPPPPPSR 315
Query: 413 RGSPRARKASRSQSETSLLGRAS-AVPSGPPKYPTAEREEPRPPRPRRGPAPTL------ 465
G P +S ET L + + ++ S P P+ R P PP P P P +
Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGR 375
Query: 466 ---------AAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAP 509
++ + R +T ++ + G P +P PS AP
Sbjct: 376 SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP 428
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 62.8 bits (151), Expect = 9e-10
Identities = 130/520 (25%), Positives = 166/520 (31%), Gaps = 98/520 (18%)
Query: 101 SLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYAS 160
S ES G S P +GG SPP + P G +
Sbjct: 615 SQESIGARSRGSGHSQEQPAPQPSGGDPSPPQE-----------------RNLPEG---T 654
Query: 161 ERPKSLGDASPSA--PEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTP 218
ERP L + P P V S AP P G P A S AGP TP
Sbjct: 655 ERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA---PWAFSYL-----AGPPATP 706
Query: 219 SPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAG-----QPRTSPG 273
RS PT+ G A P+ + + RR G P +P
Sbjct: 707 PDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT 766
Query: 274 GADGGPRRQNSV----RQRPPDASP---SPGSARPAREPSLERVGGHPTSPAALSRAWAS 326
A G PR Q+ R+ PP P S S P L+ G R S
Sbjct: 767 PARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLS 826
Query: 327 SWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLP-----GRAARRKPPP 381
E EP PPA P E P ++ GLP +++P P
Sbjct: 827 --EPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKP 884
Query: 382 LTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAV--PS 439
PPRE P G + E+ + P+ R+ Q+ G ASA P+
Sbjct: 885 AG-------PPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPA 937
Query: 440 GPPKYPTAEREEPRPPRPRRGP------------APTLAAQ-----------AAGSCRRW 476
P PT P P+ P AP+ A Q + + RW
Sbjct: 938 APLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRW 997
Query: 477 RSTAEIDAADGRRVRPRAPAA--RVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPL-- 532
+G P APAA +VPG G +P P A S + A RLGP
Sbjct: 998 ---------NGETEPPAAPAALLKVPGAGTAPK-PVSVACTQLAFSGPKL-APRLGPRPV 1046
Query: 533 --GRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGS 570
R G VG G + + A A+ S G+
Sbjct: 1047 PPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGT 1086
Score = 58.5 bits (140), Expect = 2e-08
Identities = 125/501 (24%), Positives = 160/501 (31%), Gaps = 121/501 (24%)
Query: 201 EACSSAERRARAGPFL--------TPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGY 252
E + E A AGP L +P A+A P P PP SP G
Sbjct: 567 EGLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIG------ 620
Query: 253 ISALLRRRRRRGAG----QPRTSPGGADGGPRRQNSV---RQRPPD-ASPSPGSARPARE 304
R RG+G QP P G D P ++ ++ +RPP S PG P
Sbjct: 621 -------ARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYV 673
Query: 305 PSLERVGGHPTSPA---ALSRAWASSWESEAAPEPAAPP---------AAPSPPDSPAEG 352
+ G P+SPA WA S+ + P PP + P P + AEG
Sbjct: 674 FMYPQ--GSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEG 731
Query: 353 RLV-KAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRA------AGRRG- 404
G+ A PGR+A + P SV +P R PR+ A R+G
Sbjct: 732 EAEGPVGSTLGSYATLTRRPGRSALVRTSP-----SVTPTPARGTPRSQSFALRARRKGP 786
Query: 405 ------RMAEASGRRGSPRARKASRSQSE--TSLLGRASAVPSGPPKYP----------T 446
R++ SG P S E T R + P+GP + P
Sbjct: 787 PPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASD 846
Query: 447 AEREEPRP--------------------------------PRPRRGPAP---------TL 465
E EEP P P PR P P +
Sbjct: 847 TEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESD 906
Query: 466 AAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGS-DSEC 524
+ CR A G PAA +P P P S P L S ++
Sbjct: 907 TVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQG 966
Query: 525 SAGRLGPLGRRGPAGGVGGGYGESESSAS----EGESPAFSSASSDSDGSGGLVWPQQLV 580
L P P G G S+AS E E PA +A G+G P V
Sbjct: 967 VPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVS-V 1025
Query: 581 AATAASGGGAGAGAPAGPAKV 601
A T + G GP V
Sbjct: 1026 ACTQLAFSGPKLAPRLGPRPV 1046
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 62.8 bits (151), Expect = 9e-10
Identities = 130/520 (25%), Positives = 166/520 (31%), Gaps = 98/520 (18%)
Query: 101 SLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYAS 160
S ES G S P +GG SPP + P G +
Sbjct: 697 SQESIGARSRGSGHSQEQPAPQPSGGDPSPPQE-----------------RNLPEG---T 736
Query: 161 ERPKSLGDASPSA--PEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTP 218
ERP L + P P V S AP P G P A S AGP TP
Sbjct: 737 ERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA---PWAFSYL-----AGPPATP 788
Query: 219 SPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAG-----QPRTSPG 273
RS PT+ G A P+ + + RR G P +P
Sbjct: 789 PDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT 848
Query: 274 GADGGPRRQNSV----RQRPPDASP---SPGSARPAREPSLERVGGHPTSPAALSRAWAS 326
A G PR Q+ R+ PP P S S P L+ G R S
Sbjct: 849 PARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLS 908
Query: 327 SWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLP-----GRAARRKPPP 381
E EP PPA P E P ++ GLP +++P P
Sbjct: 909 --EPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKP 966
Query: 382 LTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAV--PS 439
PPRE P G + E+ + P+ R+ Q+ G ASA P+
Sbjct: 967 AG-------PPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPA 1019
Query: 440 GPPKYPTAEREEPRPPRPRRGP------------APTLAAQ-----------AAGSCRRW 476
P PT P P+ P AP+ A Q + + RW
Sbjct: 1020 APLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRW 1079
Query: 477 RSTAEIDAADGRRVRPRAPAA--RVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPL-- 532
+G P APAA +VPG G +P P A S + A RLGP
Sbjct: 1080 ---------NGETEPPAAPAALLKVPGAGTAPK-PVSVACTQLAFSGPKL-APRLGPRPV 1128
Query: 533 --GRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGS 570
R G VG G + + A A+ S G+
Sbjct: 1129 PPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGT 1168
Score = 58.5 bits (140), Expect = 2e-08
Identities = 125/501 (24%), Positives = 160/501 (31%), Gaps = 121/501 (24%)
Query: 201 EACSSAERRARAGPFL--------TPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGY 252
E + E A AGP L +P A+A P P PP SP G
Sbjct: 649 EGLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIG------ 702
Query: 253 ISALLRRRRRRGAG----QPRTSPGGADGGPRRQNSV---RQRPPD-ASPSPGSARPARE 304
R RG+G QP P G D P ++ ++ +RPP S PG P
Sbjct: 703 -------ARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYV 755
Query: 305 PSLERVGGHPTSPA---ALSRAWASSWESEAAPEPAAPP---------AAPSPPDSPAEG 352
+ G P+SPA WA S+ + P PP + P P + AEG
Sbjct: 756 FMYPQ--GSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEG 813
Query: 353 RLV-KAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRA------AGRRG- 404
G+ A PGR+A + P SV +P R PR+ A R+G
Sbjct: 814 EAEGPVGSTLGSYATLTRRPGRSALVRTSP-----SVTPTPARGTPRSQSFALRARRKGP 868
Query: 405 ------RMAEASGRRGSPRARKASRSQSE--TSLLGRASAVPSGPPKYP----------T 446
R++ SG P S E T R + P+GP + P
Sbjct: 869 PPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASD 928
Query: 447 AEREEPRP--------------------------------PRPRRGPAP---------TL 465
E EEP P P PR P P +
Sbjct: 929 TEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESD 988
Query: 466 AAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGS-DSEC 524
+ CR A G PAA +P P P S P L S ++
Sbjct: 989 TVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQG 1048
Query: 525 SAGRLGPLGRRGPAGGVGGGYGESESSAS----EGESPAFSSASSDSDGSGGLVWPQQLV 580
L P P G G S+AS E E PA +A G+G P V
Sbjct: 1049 VPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVS-V 1107
Query: 581 AATAASGGGAGAGAPAGPAKV 601
A T + G GP V
Sbjct: 1108 ACTQLAFSGPKLAPRLGPRPV 1128
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 62.4 bits (150), Expect = 1e-09
Identities = 135/515 (26%), Positives = 165/515 (32%), Gaps = 95/515 (18%)
Query: 119 EDPSSTGGPDSPPSTFCGDSGFSGSSS-YGRLGPSEPRGIYASERPKSLG--------DA 169
+ P G + PP G+ G G G +G PRG+ ++ + L D
Sbjct: 759 DGPPGHPGKEGPP----GEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDG 814
Query: 170 SPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRS- 228
P +G + R P P G GPE + R GP P PL +
Sbjct: 815 FPGFKGDMGIKG--DRGEIGP-PGPRGEDGPEG-----PKGRGGPNGDPGPLGPPGEKGK 866
Query: 229 ---PRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADG--GPRRQN 283
P G P P G G P G+ A + R G+P P G G GPR +
Sbjct: 867 LGVPGLPGYPGRQGPK-GSIGFP--GFPGANGEKGGRGTPGKP--GPRGQRGPTGPRGER 921
Query: 284 SVR--QRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPA 341
R P + G PA P ER P P P P PP
Sbjct: 922 GPRGITGKPGPKGNSGGDGPAGPPG-ERGPNGPQGPTGF-------------PGPKGPPG 967
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLT--RGRSVEQSPPRER--- 396
P P PG + T G G+ PP + +G + E P ER
Sbjct: 968 PPGKDGLPGH---------PGQRGET-GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHP 1017
Query: 397 --PRAAGRRGR--MAEASGRRGSPRARKASRSQSETSLLG----RASAVPSGPPKYPTAE 448
P G +G +A G +G P L G R P G E
Sbjct: 1018 GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077
Query: 449 REEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSA 508
P PP P P A AAG I G P+ P PGP A
Sbjct: 1078 GP-PGPPGPAGSPGERGPAGAAGPIG-------IPGRPG----PQGP----PGPAGEKGA 1121
Query: 509 PQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGE-SPAFSSASSDS 567
P + G AG D G GP+G GPAG VG GE GE S
Sbjct: 1122 PGEKGPQGPAGRD-----GLQGPVGLPGPAGPVGPP-GEDGDKGEIGEPGQKGSKGDKGE 1175
Query: 568 DGSGGLVWPQQLVAATAASGGGAGAGAPAGPAKVF 602
G G PQ + SG G P G +F
Sbjct: 1176 QGPPGPTGPQGPIGQPGPSGAD-GEPGPRGQQGLF 1209
Score = 57.0 bits (136), Expect = 5e-08
Identities = 105/414 (25%), Positives = 135/414 (32%), Gaps = 76/414 (18%)
Query: 116 GFYEDPSSTG--GPDSPPSTFCGDSGFSGS-SSYGRLGPSEPRGIYASERPKSLGDASPS 172
GF P G G PP G+ G +G G GP PRG S P + G P
Sbjct: 1219 GFPGPPGPVGLQGLPGPP----GEKGETGDVGQMGPPGPPGPRG--PSGAPGADGPQGPP 1272
Query: 173 A----PEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRS 228
P VG + + P GG GP+ + +GP P
Sbjct: 1273 GGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG--ERGEKGESGPSGAAGP-------- 1322
Query: 229 PRPCGRPPTDSPDA--GGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVR 286
P P G P D P G G P D G+P P G DG P +
Sbjct: 1323 PGPKGPPGDDGPKGSPGPVGFPGDP-----------GPPGEP--GPAGQDGPPGDKGDDG 1369
Query: 287 QRPPDASPSP-GSARPAREPSLERVGGHPTSPAALSRAWASSWES--EAAPEPAAPPAAP 343
+ SP P G P+ P G P P + E+ E P P
Sbjct: 1370 EPGQTGSPGPTGEPGPSGPPGKRGPPG-PAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428
Query: 344 SPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPP-----PLTRGRSVEQSPPRER-- 396
P P L + IPG +GLPG PP P G + P E+
Sbjct: 1429 GAPGKPGPDGL---RGIPGP-VGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGH 1484
Query: 397 PRAAGRRGRMAEAS--GRRGSPRARKASRSQSETSLLGRASAV-PSGPPKYP-------- 445
P G G E G RG P + +S + E + G + + P GPP P
Sbjct: 1485 PGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGA 1544
Query: 446 ---------TAEREEPRPPRPRRGPAPT---LAAQAAGSCRRWRSTAEIDAADG 487
E P PP P P L QA+ + R ++ +D +G
Sbjct: 1545 KGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDDGNG 1598
Score = 54.3 bits (129), Expect = 3e-07
Identities = 129/524 (24%), Positives = 152/524 (29%), Gaps = 121/524 (23%)
Query: 106 GLEQESGRSSGFYEDPSSTG--GPDSPPST--FCGDSGFSGSSSY----GRLGPSEPRGI 157
GL +G+ G DP G G D PP F GD G G G GP P G
Sbjct: 1027 GLPGLAGKE-GTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGP 1085
Query: 158 YASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAG--GSAGPEACSSAERRARAGPF 215
S P G A + P + R P+ P G G GP+ A R GP
Sbjct: 1086 AGS--PGERGPAGAAGPIGIPGRPG-PQGPPGPAGEKGAPGEKGPQG--PAGRDGLQGPV 1140
Query: 216 LTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPR-----T 270
P P V PP + D G G P + G P+
Sbjct: 1141 GLPGPAGPVG---------PPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQP 1191
Query: 271 SPGGADG--GPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSW 328
P GADG GPR Q + + D P G P P
Sbjct: 1192 GPSGADGEPGPRGQQGLFGQKGDEGPR----------------GFPGPPG---------- 1225
Query: 329 ESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSV 388
P P PP E G PG R P G
Sbjct: 1226 -------PVGLQGLPGPPGEKGET----------GDVGQMGPPGPPGPRGPSGAP-GADG 1267
Query: 389 EQSPPRE--RPRAAGRRGRMAEAS-----GRRGSPRARKASRSQSETSLLGRASAV-PSG 440
Q PP P A G +G EA G G P + + E+ G A P G
Sbjct: 1268 PQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG 1327
Query: 441 PPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAAR-V 499
PP + P P P P AG D G + P
Sbjct: 1328 PPG-DDGPKGSPGPVGFPGDPGPPGEPGPAGQ----------DGPPGDKGDDGEPGQTGS 1376
Query: 500 PGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVG--GGYGESESSASEG-E 556
PGP P G GP G+RGP G G G GE + G E
Sbjct: 1377 PGPTGEP--------------------GPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLE 1416
Query: 557 SPAFSSASSDSDGSGGLVWPQQL--VAATAASGGGAGAGAPAGP 598
P + G+ G P L + G G+ P GP
Sbjct: 1417 GPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460
Score = 43.1 bits (100), Expect = 8e-04
Identities = 126/544 (23%), Positives = 170/544 (31%), Gaps = 140/544 (25%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGAR 180
P G PP T G +G G G GP G+ + D P P G
Sbjct: 473 PEGPAGLPGPPGTM-GPTGQVGDP--GERGPPGRPGLPGA-------DGLPGPP---GTM 519
Query: 181 AAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRP----CGRP- 235
+P F GG AG + + + ++A L + L A+R P GRP
Sbjct: 520 LMLPFRFGG-----GGDAGSKGPMVSAQESQAQAILQQARL---ALRGPAGPMGLTGRPG 571
Query: 236 PTDSPDAGGA-GRPLDGYISALLRRRRRRGAGQPR--TSPGGADGGPRRQNSVRQRPPDA 292
P P +GG G P D G PR P G G P R+ R A
Sbjct: 572 PVGPPGSGGLKGEPGDV------------GPQGPRGVQGPPGPAGKPGRRG--RAGSDGA 617
Query: 293 SPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEG 352
PG P + + + G P P P+ PP P +
Sbjct: 618 RGMPGQTGPKGDRGFDGLAGLPGEKG-----------HRGDPGPSGPPGPPGDDGERGDD 666
Query: 353 RLVKAQYIPGAQAATRGLPGRAARRKPP--PLTRGRSVEQSP-----PRERPRAAGRRGR 405
V + +PG + RGL G PP P G + P P+ P G++G
Sbjct: 667 GEVGPRGLPG-EPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGN 725
Query: 406 MAEASGRRGSPRARKASRSQSETSLLGRAS--AVPS--GPPKYPTAE--------REEPR 453
G +G P + A E LG+ +P GPP +P E + P
Sbjct: 726 ----PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPG 781
Query: 454 PPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADG-----------------------RRV 490
P P P P + A R + T DG
Sbjct: 782 PQGPIGYPGPR-GVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGED 840
Query: 491 RPRAPAAR--------------------VPG-PG-PSPSAPQRRLLY-GCAGSDSECSA- 526
P P R VPG PG P P+ + + G G++ E
Sbjct: 841 GPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGR 900
Query: 527 ------------GRLGPLGRRGPAGGVGGGYGESESSASEGES-PAFSSASSDSDGSGGL 573
G GP G RGP G+ G G +S +G + P + G G
Sbjct: 901 GTPGKPGPRGQRGPTGPRGERGPR-GITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959
Query: 574 VWPQ 577
P+
Sbjct: 960 PGPK 963
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 61.6 bits (148), Expect = 2e-09
Identities = 127/509 (24%), Positives = 179/509 (35%), Gaps = 57/509 (11%)
Query: 55 AEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQESGRS 114
A ++ ++D D+ A R + + P + D +L SG + +
Sbjct: 1551 ASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV--DSKSRLSPRRSRSGSSPEVKDKP 1608
Query: 115 SGFYEDPS---STGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASER-----PKS- 165
S S+ P +P SGSSS GR GPS P G ++E PKS
Sbjct: 1609 RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR-GPS-PEGSSSTESSPEHPPKSR 1666
Query: 166 -LGDASPSAPEVVGARAAVPR---SFSAPYPTA---------GGSAGPEACSSAERRARA 212
S S+PE PR S S+P T S+ PE S R R
Sbjct: 1667 TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR 1726
Query: 213 GPFLTPSPLHAVAMRSPRPC--------------GRPPTDSPDAGGAGRPLDGYISALLR 258
P ++ SP A RS R GR P+ P R
Sbjct: 1727 SPSVS-SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTT 1785
Query: 259 RRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDA--SPSPGSARPAREPSLERVGGHPTS 316
RRR R TS R + + R+R S SP +R S R G T
Sbjct: 1786 RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP 1845
Query: 317 PAALSRA--------WASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATR 368
P + R+ W S S A+P + +P S R + +
Sbjct: 1846 PTSRKRSRSRTSPAPWKRS-RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT 1904
Query: 369 GLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSET 428
+ R +R + P++R RS ++PP R R+ R S R P R+ SRS++
Sbjct: 1905 SVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPP 1964
Query: 429 SLLGRASAVPSGPPKYPTAEREEP---RPPRPRRGPAPTLAAQAAGS-CRRWRSTAEIDA 484
R+ + S + + R P R R R P +++ S R RS +
Sbjct: 1965 VTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPP 2024
Query: 485 ADGRRVRPRAP-AARVPGPGPSPSAPQRR 512
A RR R R P R SP A +RR
Sbjct: 2025 AIRRRSRSRTPLLPRKRSRSRSPLAIRRR 2053
Score = 60.1 bits (144), Expect = 6e-09
Identities = 114/456 (25%), Positives = 161/456 (35%), Gaps = 88/456 (19%)
Query: 138 SGFSGSSSYGRLGP-----SEPRGIYASERPKSLGDAS--PSAPEVVGARAAVPRSFSAP 190
+G S S + GR G SEP G +++RP S A+ PS+P + +S + P
Sbjct: 292 AGRSPSPASGRRGEGDAPFSEP-GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP 350
Query: 191 YPTAG-GSAGPEACSS----AERRARAGPFLTPSPLHAVAMRSPRPCG----RPPTDSPD 241
P+ S GPE + AER + L +PL + P R P SP+
Sbjct: 351 SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPE 410
Query: 242 -----AGGAGRPLDGYISALLRRRR--------------RRGAGQPRTSPGGADGGPRRQ 282
+ P + + R R TS + G +R
Sbjct: 411 KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRD 470
Query: 283 NSVRQRPP---DASPSPGSARPAREPS---LERVGGHPTSPAALSRAWASSWESEAAPEP 336
S P S SP +A+ R S +R SP A W +P+
Sbjct: 471 KSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR 530
Query: 337 AAPPAAPSPPD---SPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPP 393
+P P S R +++ ++ +R R R P RGRS ++P
Sbjct: 531 RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPA 590
Query: 394 RERPRAAG--RRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREE 451
R R R+ RR + RRG R+R +R +S T + P R
Sbjct: 591 RRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRT--------------RSPVRRRSR 636
Query: 452 PRPPRPRRG------PAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPA------ARV 499
R P R G PA +++ RR RS + A R R R PA +R
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696
Query: 500 PGPGPSPS------------APQRRLLYGCAGSDSE 523
P G S S PQRR G +GS SE
Sbjct: 697 PRRGRSRSRSLVRRGRSHSRTPQRR---GRSGSSSE 729
Score = 58.5 bits (140), Expect = 2e-08
Identities = 98/425 (23%), Positives = 145/425 (34%), Gaps = 72/425 (16%)
Query: 121 PSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRG--IYASERPKSLGDASPSAPEVVG 178
PSS+ P +P S + G S P G A+ P SL A AP + G
Sbjct: 2324 PSSSRTPQAPAS-----ANLVGPRSAHATAPVNIAGSRTAAALAPASLTSAR-MAPALSG 2377
Query: 179 ARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPC---GRP 235
A PR + Y G P A R P PS + R+P P G+
Sbjct: 2378 ANLTSPRVPLSAYERVSGRTSPPLLDRARSRT---PPSAPSQSRMTSERAPSPSSRMGQA 2434
Query: 236 PTDSPDAGGAGRPLDGYISALLRRRR---------------RRGAGQPRTSPGGADGGPR 280
P+ S +P SA + R GA TS G G
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGML 2494
Query: 281 R-------QNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAA 333
+ V + P SA A +P+ ER +S ++ S + +SS S ++
Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554
Query: 334 PEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPP-------LTRGR 386
++ S +EG + Q P A +R P P + GR
Sbjct: 2555 SSGSS--------SSDSEGSSLPVQ------------PEVALKRVPSPTPAPKEAVREGR 2594
Query: 387 SVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPT 446
E +P + + R++ + +S S + +S S S +S +S+ S P
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654
Query: 447 AEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDA-ADGRRVRPRAPAARVPGPGPS 505
+ P+P P++ P G R ID+ D R + R P P PS
Sbjct: 2655 GPQALPKPASPKKPP--------PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706
Query: 506 PSAPQ 510
P Q
Sbjct: 2707 PRDQQ 2711
Score = 55.1 bits (131), Expect = 2e-07
Identities = 91/364 (25%), Positives = 128/364 (35%), Gaps = 64/364 (17%)
Query: 204 SSAERRARAGPFLTP---SPLHAVAMRSPRPCGRPPTD-SPDA-GGAGRPLDGYISA--- 255
SS + GPFL P + +S R G ++ SPDA AG + IS+
Sbjct: 1348 SSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVL 1407
Query: 256 -LLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHP 314
+ R R +SP DG PR + + GS P+R G
Sbjct: 1408 DAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMK 1467
Query: 315 TSPAALSRAWASSWESEAAPEPAAPPAAPSPPD-SPAEGRLVKAQYIPGAQAATRGLPGR 373
P SR + E +++PEP A P P P SP+ L P + +
Sbjct: 1468 DIPRTPSRGRS---ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSE---- 1520
Query: 374 AARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGR 433
SV+Q P G+R R + P A RS+S++S
Sbjct: 1521 ------------SSVDQKTVARTP--LGQRSRSGSSQELDVKPSASPQERSESDSS---- 1562
Query: 434 ASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPR 493
P K T R+ R R G +P + +++ S RR RS + + D R PR
Sbjct: 1563 ----PDSKAKTRTPLRQ-----RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
Query: 494 APAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSAS 553
A + P P AP+ L RR +G G G S +S
Sbjct: 1614 AQSGSDSSPEPKAPAPR--------------------ALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 554 EGES 557
ES
Sbjct: 1654 STES 1657
Score = 53.9 bits (128), Expect = 4e-07
Identities = 126/520 (24%), Positives = 181/520 (34%), Gaps = 80/520 (15%)
Query: 112 GRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPK-----SL 166
GR S+ P+ PP + G S + PR + P+ L
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 167 GDASPSAPEVVGARAAVPR------SFSAPYPTAGG-------SAGPEACSSAERRARAG 213
S SA R+ P S S+P P SA + RR R+
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRS- 1762
Query: 214 PFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLD-----GYISALLRRRRRRGAGQP 268
P P L RS R R T D G+ + + + RRRR G+G
Sbjct: 1763 PSPKPRGLQRSRSRSRREKTRT-TRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH 1821
Query: 269 RTSPGGADGG---PRRQNSVRQRPPDA--------SPSP-----GSARPA-------REP 305
SP + RR+ + PP + SP+P A PA R P
Sbjct: 1822 SRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881
Query: 306 SLERVGGHP-TSPAALSRAWASSW------ESEAAPEPAAPPAAPSPPDSPAEGRLVKAQ 358
+ R TSP + R+ + + S A+P + +PP + R
Sbjct: 1882 LISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPT 1941
Query: 359 YIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGR-RGSPR 417
+++ T + R +R + PP+TR RS ++ P R R+ R + R R SP
Sbjct: 1942 TRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPV 2001
Query: 418 ARKASRSQSETSLLGRASAVPSGPPKYPTAEREE-PRPPRPRRGPAPTLAAQAAGSCRRW 476
R+ RS+S TS + R + PP R P PR R LA + R
Sbjct: 2002 TRR--RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059
Query: 477 RSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRG 536
R+ A G+R R SP A +RR +GS S+ S P R
Sbjct: 2060 RT------ARGKRSLTR-----------SPPAIRRR---SASGSSSDRSRSATPP-ATRN 2098
Query: 537 PAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWP 576
+G + S S P+ S D S G++ P
Sbjct: 2099 HSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEP 2138
Score = 48.1 bits (113), Expect = 2e-05
Identities = 91/394 (23%), Positives = 134/394 (34%), Gaps = 51/394 (12%)
Query: 155 RGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACS---------- 204
RG S P G + +P+ +R+A S G S P+
Sbjct: 492 RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRR 551
Query: 205 SAERRARAGPFLTPSPLHAVAMRSPRPC--GRPPTDSPDAGGAGRPLDGYISALLRRRRR 262
R AR G + SP RS P GR + +P + + R R
Sbjct: 552 GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR 611
Query: 263 RGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSR 322
RG + RT A R ++ VR+R SP+ S R R +PA R
Sbjct: 612 RGRSRSRTP---ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668
Query: 323 AWASSWESEAAPEPAAPPA--APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPP 380
+ + + + + PA S +P GR + +R L R
Sbjct: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR-----------SRSRSLVRRGRSHSRT 717
Query: 381 PLTRGRSVEQSPPRERPRAAGRRGR--------MAEASGRR----GSPRARKASRSQSET 428
P RGRS S + + R + RR R + S RR SPR++ SR
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 429 SLLGRASAVP----SGPPKYPTAEREEPR------PPRPRRGPAPTLAAQAAGSCRRWRS 478
SL G +S P PP+ + +P+ P R R +P ++ R+ S
Sbjct: 778 SLSG-SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHS 836
Query: 479 TAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRR 512
++ PR + P PQRR
Sbjct: 837 SSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Score = 47.8 bits (112), Expect = 3e-05
Identities = 75/342 (21%), Positives = 118/342 (34%), Gaps = 61/342 (17%)
Query: 98 GDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGI 157
G SL SG + + S+G + S P P S +G+ L +P
Sbjct: 2471 GSQSLSSGAVATTTS-SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQP--- 2526
Query: 158 YASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLT 217
A ER S +S S+ + ++ S S+ ++ S G E + P T
Sbjct: 2527 -AKERRSSSSSSSSSSSS--SSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 218 PSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADG 277
P+P AV GRPP +P +R+RR + +S +
Sbjct: 2584 PAPKEAVRE------GRPPEPTP----------------AKRKRRSSSSSSSSSSSSSSS 2621
Query: 278 GPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPA 337
+S +S S S+ + PS P P +A P+PA
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPS-------PAKPGP-----------QALPKPA 2663
Query: 338 APPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLP-GRAARRKPPPLTRGRSVEQSPPRER 396
+P P P E R + + +R L RR+P P Q PR++
Sbjct: 2664 SPKKPP-----PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP--------QPSPRDQ 2710
Query: 397 PRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVP 438
++ RG G SP ++ + S + R+S P
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 47.0 bits (110), Expect = 5e-05
Identities = 111/507 (21%), Positives = 160/507 (31%), Gaps = 75/507 (14%)
Query: 122 SSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGARA 181
+S P P + DS +++ L + PR A +P+AP V A A
Sbjct: 2243 ASARTPAIPTAVNLADSRTPAAAAAMNL--ASPRTAVAPSAVNLADPRTPTAPAVNLAGA 2300
Query: 182 AVPRSFSAPYPTAGGSAGPEACSSAERRARAGP----FLTPSPLHAVAMRSPRPCGRPPT 237
P + +A T G+ A + R P + P HA A +
Sbjct: 2301 RTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA 2360
Query: 238 DSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPG 297
+P + + R A L R + R S P + R R P ++PS
Sbjct: 2361 LAPASLTSARMAPALSGANLTSPRVPLSAYERVS---GRTSPPLLDRARSRTPPSAPSQS 2417
Query: 298 SARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKA 357
R PS G S + L P P +P P + R + A
Sbjct: 2418 RMTSERAPSPSSRMGQAPSQSLL-------------PPAQDQPRSPVPSAFSDQSRCLIA 2464
Query: 358 QYIP---------GAQAATRGLPG--RAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRM 406
Q P GA A T G P P V + P + +
Sbjct: 2465 QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAAL 2524
Query: 407 AEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRP--RRGPAPT 464
A RR S + +S S S +S +S+ SG + P P +R P+PT
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSS-SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 465 LAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSEC 524
A + A VR P P P+P+ +RR + S S
Sbjct: 2584 PAPKEA-------------------VREGRP------PEPTPAKRKRRSSSSSSSSSSSS 2618
Query: 525 SAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATA 584
S+ S SS+S S + SS+SS S S PQ L +
Sbjct: 2619 SSS--------------SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664
Query: 585 ASGGGAGAGAPAGPAKVFVKIKASHAL 611
G P K ++ S +L
Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSL 2691
Score = 39.7 bits (91), Expect = 0.008
Identities = 42/146 (28%), Positives = 65/146 (44%), Gaps = 23/146 (15%)
Query: 378 KPPPLTRGRSVEQSP-PRERPRAAGR-RGRMAEASGRRGSPRA---RKASRSQSETSLLG 432
KP L R S +SP P+++ + + RGR +E+S R + +K RS+SE+
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228
Query: 433 RASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA--EIDAADGRRV 490
S P K +R+ R P A S R RST+ ++D R
Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTP-----------APKSRRAHRSTSADSASSSDTSRS 277
Query: 491 RPRAPAAR-----VPGPGPSPSAPQR 511
R R+ AA+ + G PSP++ +R
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRR 303
Score = 38.5 bits (88), Expect = 0.019
Identities = 58/232 (25%), Positives = 84/232 (36%), Gaps = 27/232 (11%)
Query: 377 RKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSE--------T 428
R P P ++ +S ++ R R + R A S S + SRS+S T
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289
Query: 429 SLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGR 488
+L GR+ + SG A EP +R +P A + S + D +
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP---YEDKDKDKKEKS 346
Query: 489 RVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGES 548
RP +P+ GP P AP L GS + L P S
Sbjct: 347 ATRP-SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP----------S 395
Query: 549 ESSASEGESPAFS----SASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPA 596
E+S + SP S SS S+ S P + V+ A+S + APA
Sbjct: 396 EASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK-VSRHASSSPESPKPAPA 446
Score = 36.6 bits (83), Expect = 0.072
Identities = 58/273 (21%), Positives = 103/273 (37%), Gaps = 25/273 (9%)
Query: 250 DGYI--SALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSL 307
D Y+ S+ +RR R A QP P P+ + VR+ SP+P + ++
Sbjct: 143 DSYVDGSSFDPQRRAREAKQPAPEP------PKPYSLVRESSSSRSPTPKQKKKKKKK-- 194
Query: 308 ERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAAT 367
+R +S R +S + + + SP +P R K + +++ T
Sbjct: 195 DRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSP--TPKSKRKSKDKKRKRSRSTT 252
Query: 368 RGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSE 427
P +RR + + R R R+A + +GR SP + + +
Sbjct: 253 ---PAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAP 309
Query: 428 TSLLGRASAV-PSGP------PKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA 480
S G S PS P P P ++++ + + P+P+ + G T
Sbjct: 310 FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP-EPPAPTP 368
Query: 481 EIDAADGRRVRPRA--PAARVPGPGPSPSAPQR 511
+ G +P A P ++ P PS ++P R
Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTR 401
Score = 35.8 bits (81), Expect = 0.12
Identities = 69/341 (20%), Positives = 109/341 (31%), Gaps = 47/341 (13%)
Query: 148 RLGPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAE 207
R G S+P+ + +S +SP + + S S+P+P P
Sbjct: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP------- 850
Query: 208 RRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQ 267
R G +P R C SPD R + + R + +
Sbjct: 851 ---RQGSITSPQANEQSVTPQRRSCFE---SSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
Query: 268 PRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASS 327
PR SP + + ++ SP S + PS RV T + S + S+
Sbjct: 905 PRQSPSRSSSPQPKVKAI------ISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 328 WESEAAPE-----PAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPL 382
ES P ++P P P + P +A T P + + P P
Sbjct: 959 VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ 1018
Query: 383 TRGR-SVEQSPPRERPRAAG------------------RRGRMAEASGRRGSPRARKASR 423
+ + S+ QS P AG +G+ + R + + +
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQ 1078
Query: 424 SQSET-SLLGRASAVPSG---PPKYPTAEREEPRPPRPRRG 460
S SE+ SL ++ P G P E P R RG
Sbjct: 1079 SHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRG 1119
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 61.6 bits (148), Expect = 2e-09
Identities = 129/510 (25%), Positives = 172/510 (33%), Gaps = 69/510 (13%)
Query: 122 SSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGARA 181
SS G SP G + R+ P+ P P S + P + G
Sbjct: 124 SSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGG 183
Query: 182 AVPRSFSAPYPTAGGSAGPEACSSAERRARAGP------FLTPSPLHAVAMRS---PRPC 232
P + P P+ GGS+ P + A P PS A+RS P
Sbjct: 184 LFPPRLADPVPS-GGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDL 242
Query: 233 GRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDA 292
G PP + P + S L P P N++ P A
Sbjct: 243 GSPPAPHASSSPPSDPPLFHCSDALT--------PPPLPPS---------NNLPAHPGPA 285
Query: 293 SPSPGSARPAREPS-LERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAE 351
S P S+ P L +GG PT + + +S AA + PP PP S +
Sbjct: 286 SQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPL---PPPSTLQ 342
Query: 352 GRLVKAQYIPGAQAATRGLPGRAARRKPPPLTR---GRSVEQSPPRERPRAAG------- 401
GR +AQ P A ++ P + R+PP + R GR Q+P R RPRA
Sbjct: 343 GRRPRAQ-APSASHSSSLRPSQRRPRRPPTVFRLLEGRG-PQTPRRSRPRAPAPVPQPFS 400
Query: 402 ----RRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRP 457
+ + G P S S +LLG + +P PP PT PP+P
Sbjct: 401 LPEPSQPILPSVLSLLGLP-TPGPSHSDGSFNLLGSDAHLP--PP--PTL--SSGSPPQP 453
Query: 458 RRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVP----GPGPSPSAPQRRL 513
R P+L +GS AA V P +P + P G G P+ P L
Sbjct: 454 RHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVP-SPVLQSPSEGLGMGAGPACPLPPL 512
Query: 514 LYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAF----SSASSDSDG 569
G A G L G G G G S G+ P S G
Sbjct: 513 AGGEAFPFPSPEQG----LALSG--AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTG 566
Query: 570 SGGLVWPQQLVAATAASGGGAGAGAPAGPA 599
GG P+ L+ G G P GP+
Sbjct: 567 GGGQPPPEPLLPPPGGPGPPLAPGEPEGPS 596
Score = 38.5 bits (88), Expect = 0.019
Identities = 56/199 (28%), Positives = 73/199 (36%), Gaps = 41/199 (20%)
Query: 163 PKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLH 222
P +L SP P + ++P + S + G+ P A S A P L SP
Sbjct: 442 PPTLSSGSPPQPRHP-IQPSLPGTTSGSLSSVPGAPAPPAASKAP--VVPSPVLQ-SPSE 497
Query: 223 AVAMRSPRPCGRPPT--------DSPDAG----GAGRPLDGYISALLRRRRRRGAGQPRT 270
+ M + C PP SP+ G GAG P G + AL GQP
Sbjct: 498 GLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFP--GMLGAL---PLPLSLGQPPP 552
Query: 271 SP-------GGADGGPRRQNSVRQRPPDAS-PSPGSARPAREPSLERVGGHPTSPAALSR 322
SP G GG Q PP+ P PG P P G P P+ L
Sbjct: 553 SPLLNHSLFGVLTGGGG------QPPPEPLLPPPGGPGPPLAP------GEPEGPSLLVA 600
Query: 323 AWASSWESEAAPEPAAPPA 341
+ S+ P P+APP+
Sbjct: 601 SLLPPPPSDLLPPPSAPPS 619
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 61.2 bits (147), Expect = 3e-09
Identities = 66/289 (22%), Positives = 105/289 (36%), Gaps = 23/289 (7%)
Query: 229 PRPCGRP---PTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSV 285
P G+P PT +P A PL +R A +P+T G + S+
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPL------------QRDASRPQTKQADIVRGESVKPSL 298
Query: 286 RQ--RPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESE--AAPEPAAPPA 341
+PP P+PG PA++P E+ P P A + P PP
Sbjct: 299 PSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAG 401
PP P AQ G++ + PG A +PP + + + + P + + G
Sbjct: 358 TTKPPAQPLGPAKPPAQQT-GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416
Query: 402 RRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGP 461
+A+ G + +A +++ + G+ A +GP K + +PP GP
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476
Query: 462 APTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPG-PSPSAP 509
A Q G + ++ P + PGP PSP P
Sbjct: 477 AKP-PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
Score = 45.1 bits (105), Expect = 2e-04
Identities = 68/314 (21%), Positives = 102/314 (32%), Gaps = 59/314 (18%)
Query: 150 GPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERR 209
GP++P +P L P V P + P G + P + +E+
Sbjct: 327 GPAKPPA-----QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 210 ARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPR 269
+ P A+ P G+ P P G +P + ++ G P
Sbjct: 382 SSEQP-------GPKALAQPPGVGKTPAQQP---GPAKPPTQQVGTPKPLAQQPGLQSPA 431
Query: 270 TSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWE 329
+PG + P P PG PA++ + T P
Sbjct: 432 KAPGPT------------KTPVQQPGPGKI-PAQQAGPGKTSAQQTGPTK---------P 469
Query: 330 SEAAPEPAAPP-----AAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTR 384
P PA PP A PP P + Q PG+ PG A KP P
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ--PGSTKPPPQQPGPA---KPSPQQP 524
Query: 385 GRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKY 444
G + PP ++P + A+ S ++ SP A +S S G S P PP
Sbjct: 525 GST---KPPSQQPGS-------AKPSAQQPSPAKPSAQQSTKPVSQTG--SGKPLQPPTV 572
Query: 445 PTAEREEPRPPRPR 458
+ ++ P P+
Sbjct: 573 SPSAKQPPSQGLPK 586
Score = 40.8 bits (94), Expect = 0.004
Identities = 91/440 (20%), Positives = 147/440 (33%), Gaps = 91/440 (20%)
Query: 109 QESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGD 168
Q SG + + P + P PP T LGP++P + G
Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTT--------KPPAQPLGPAKPPA-------QQTGS 378
Query: 169 ASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPL-HAVAMR 227
PS+ + P++ + P P G + + + + G TP PL ++
Sbjct: 379 EKPSSEQ------PGPKALAQP-PGVGKTPAQQPGPAKPPTQQVG---TPKPLAQQPGLQ 428
Query: 228 SPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQ 287
SP P T +P +P G I A + AG +TS GP + S Q
Sbjct: 429 SPAKAPGP-TKTP----VQQPGPGKIPA-------QQAGPGKTS--AQQTGPTKPPS--Q 472
Query: 288 RPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPD 347
P A P P PA+ P + P S S A P P P + P
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 348 SPAEGRLVKAQ---YIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPR------ 398
P + Q P AQ +T+ + + + P T S +Q P + P+
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592
Query: 399 -----------------AAGRRGRMAEASGRRGSPRARKAS-----RSQSETSLLGRASA 436
+ + G +P + Q + +L G +
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652
Query: 437 VPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPA 496
VPS P P+ + P T +A + S + +++ + DAA P+
Sbjct: 653 VPSSP------------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA------PKQDL 694
Query: 497 ARVPGPGPSPSAPQRRLLYG 516
++ P P P ++ L+G
Sbjct: 695 SKAPEPKKPPPLVKQPTLHG 714
Score = 36.6 bits (83), Expect = 0.072
Identities = 69/321 (21%), Positives = 123/321 (38%), Gaps = 50/321 (15%)
Query: 269 RTSPGGADGGPRRQNSVRQRPPDASPSPGSARP---AREPSLERVGGHPTSPAALSRAWA 325
++SP P++ + +Q D S +P +P ++P+L G P++ A A
Sbjct: 674 KSSPQPQQTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTLH---GSPSAKAKQPPE-A 726
Query: 326 SSWESEAAP-EPAAPPA---APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPP 381
S A P EP+ P AP D P + ++VK T L ++ P
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP---------TTDLVSSSSATTKPD 777
Query: 382 LTRGRSVEQSPPRERPRAAGRRGRMAEA---SGRRGSPRARKA-SRSQSETSLL---GRA 434
+ + Q+ + P + +++ +G + SP KA R S++ ++ G +
Sbjct: 778 IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS 837
Query: 435 SAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCR--RWRSTA-EIDAADGRRVR 491
S P ++EEP+ + + P P GS R TA + + +
Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK 897
Query: 492 PRAPAAR--------VPGPGPSPSAPQRRL---LYG------CAGSDSECSAGRLGPLGR 534
P+ + R P P+ PQ + L+G S+ +AG+ GP +
Sbjct: 898 PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ 957
Query: 535 RGPAGGVGGGYGESESSASEG 555
GP + S+ S+G
Sbjct: 958 SGPGAPMKQAPAPSQPPTSQG 978
Score = 33.9 bits (76), Expect = 0.47
Identities = 49/216 (22%), Positives = 74/216 (34%), Gaps = 20/216 (9%)
Query: 266 GQPRTSPGGADGGPRRQNSVRQRPPDASPSP-GSARP--AREPSLERVGGHPTSPAALSR 322
GQ + P P++ + PDA P P GS P R + + V SP +
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
Query: 323 AWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQA----ATRGLP------G 372
+ S + + AP + P+ P G+L +QA +T G P G
Sbjct: 902 SRRFSLNLGSITD--APKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959
Query: 373 RAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLG 432
A K P Q PP+ +A + +P A K + +
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 433 RASAVPSGPP----KYPTAEREEP-RPPRPRRGPAP 463
R PP K TAE ++ P + + P P
Sbjct: 1020 RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP 1055
Score = 32.3 bits (72), Expect = 1.4
Identities = 95/433 (21%), Positives = 148/433 (34%), Gaps = 67/433 (15%)
Query: 98 GDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGI 157
G + + G + S + +G + PS GP PP G + PS+ G
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG- 505
Query: 158 YASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLT 217
P+ G A PS P+ G+ + P GSA P SA++ + A P
Sbjct: 506 STKPPPQQPGPAKPS-PQQPGS--------TKPPSQQPGSAKP----SAQQPSPAKPSAQ 552
Query: 218 PSPLHAVAMRSPRPCGRPPTDSPDAGGAGR--------PLDGYISALLRRRRRRG----- 264
S S +P +PPT SP A PL LL +
Sbjct: 553 QSTKPVSQTGSGKPL-QPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 265 -AGQPRTSPGGADGGPRRQ--------NSVRQRPPDASPSPGSARPAREPSLERVGGHPT 315
S G + P N +R +P + P +P L+ T
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTTT 669
Query: 316 SPAALS--RAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGR 373
S + S + +S + +AAP+ AP P P LVK Q G P
Sbjct: 670 SAVSKSSPQPQQTSPKKDAAPKQDL-SKAPEPKKPPP---LVK-------QPTLHGSP-- 716
Query: 374 AARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGR 433
+A+ K PP S+ + P + P + + A + P+ K + +S
Sbjct: 717 SAKAKQPP--EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 434 ASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRV-RP 492
+PS K + E+ PP P+ + G ++ D + + RP
Sbjct: 775 KPDIPSS--KVQSQAEEKTTPPLKTDSAKPSQSFPPTGE--------KVSPFDSKAIPRP 824
Query: 493 RAPAARVPGPGPS 505
+ + + PGPS
Sbjct: 825 ASDSKIISHPGPS 837
Score = 31.6 bits (70), Expect = 2.3
Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 296 PGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSP 349
P S P+ PS+ + P P R+ + ++ P P PP P PP P
Sbjct: 2372 PASQLPSGSPSVSSL---PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Score = 30.8 bits (68), Expect = 3.9
Identities = 47/193 (24%), Positives = 71/193 (36%), Gaps = 23/193 (11%)
Query: 220 PLHAVAMRSPRPCGRP-PTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSP--GGAD 276
P A SP+P +P P SP G RP G ++ + R S G
Sbjct: 855 PKKAQTKMSPKPDAKPMPKGSPTPPGP-RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 277 GGPRRQNSVRQRPPDASPSP-GSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE 335
P+ Q + Q G++ ++ +L G P P + S A + AP
Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP-GPHSQSGPGAPM---KQAPA 969
Query: 336 PAAPPAAPSPPDSPAEGRLVKAQYIP-----GAQAATRGLP---------GRAARRKPPP 381
P+ PP + PP S + A+ IP A AA + P +KPPP
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Query: 382 LTRGRSVEQSPPR 394
+ +S+ P +
Sbjct: 1030 IKDSKSLTAEPQK 1042
Score = 30.0 bits (66), Expect = 6.7
Identities = 13/24 (54%), Positives = 17/24 (70%)
Query: 576 PQQLVAATAASGGGAGAGAPAGPA 599
P+ L AA AA GG +GAG+P+ A
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTA 36
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 61.2 bits (147), Expect = 3e-09
Identities = 66/289 (22%), Positives = 105/289 (36%), Gaps = 23/289 (7%)
Query: 229 PRPCGRP---PTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSV 285
P G+P PT +P A PL +R A +P+T G + S+
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPL------------QRDASRPQTKQADIVRGESVKPSL 298
Query: 286 RQ--RPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESE--AAPEPAAPPA 341
+PP P+PG PA++P E+ P P A + P PP
Sbjct: 299 PSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357
Query: 342 APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAG 401
PP P AQ G++ + PG A +PP + + + + P + + G
Sbjct: 358 TTKPPAQPLGPAKPPAQQT-GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416
Query: 402 RRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGP 461
+A+ G + +A +++ + G+ A +GP K + +PP GP
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476
Query: 462 APTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPG-PSPSAP 509
A Q G + ++ P + PGP PSP P
Sbjct: 477 AKP-PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
Score = 45.1 bits (105), Expect = 2e-04
Identities = 68/314 (21%), Positives = 102/314 (32%), Gaps = 59/314 (18%)
Query: 150 GPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERR 209
GP++P +P L P V P + P G + P + +E+
Sbjct: 327 GPAKPPA-----QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 210 ARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPR 269
+ P A+ P G+ P P G +P + ++ G P
Sbjct: 382 SSEQP-------GPKALAQPPGVGKTPAQQP---GPAKPPTQQVGTPKPLAQQPGLQSPA 431
Query: 270 TSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWE 329
+PG + P P PG PA++ + T P
Sbjct: 432 KAPGPT------------KTPVQQPGPGKI-PAQQAGPGKTSAQQTGPTK---------P 469
Query: 330 SEAAPEPAAPP-----AAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTR 384
P PA PP A PP P + Q PG+ PG A KP P
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ--PGSTKPPPQQPGPA---KPSPQQP 524
Query: 385 GRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKY 444
G + PP ++P + A+ S ++ SP A +S S G S P PP
Sbjct: 525 GST---KPPSQQPGS-------AKPSAQQPSPAKPSAQQSTKPVSQTG--SGKPLQPPTV 572
Query: 445 PTAEREEPRPPRPR 458
+ ++ P P+
Sbjct: 573 SPSAKQPPSQGLPK 586
Score = 40.8 bits (94), Expect = 0.004
Identities = 91/440 (20%), Positives = 147/440 (33%), Gaps = 91/440 (20%)
Query: 109 QESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGD 168
Q SG + + P + P PP T LGP++P + G
Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTT--------KPPAQPLGPAKPPA-------QQTGS 378
Query: 169 ASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPL-HAVAMR 227
PS+ + P++ + P P G + + + + G TP PL ++
Sbjct: 379 EKPSSEQ------PGPKALAQP-PGVGKTPAQQPGPAKPPTQQVG---TPKPLAQQPGLQ 428
Query: 228 SPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQ 287
SP P T +P +P G I A + AG +TS GP + S Q
Sbjct: 429 SPAKAPGP-TKTP----VQQPGPGKIPA-------QQAGPGKTS--AQQTGPTKPPS--Q 472
Query: 288 RPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPD 347
P A P P PA+ P + P S S A P P P + P
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 348 SPAEGRLVKAQ---YIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPR------ 398
P + Q P AQ +T+ + + + P T S +Q P + P+
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592
Query: 399 -----------------AAGRRGRMAEASGRRGSPRARKAS-----RSQSETSLLGRASA 436
+ + G +P + Q + +L G +
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652
Query: 437 VPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPA 496
VPS P P+ + P T +A + S + +++ + DAA P+
Sbjct: 653 VPSSP------------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA------PKQDL 694
Query: 497 ARVPGPGPSPSAPQRRLLYG 516
++ P P P ++ L+G
Sbjct: 695 SKAPEPKKPPPLVKQPTLHG 714
Score = 36.6 bits (83), Expect = 0.072
Identities = 69/321 (21%), Positives = 123/321 (38%), Gaps = 50/321 (15%)
Query: 269 RTSPGGADGGPRRQNSVRQRPPDASPSPGSARP---AREPSLERVGGHPTSPAALSRAWA 325
++SP P++ + +Q D S +P +P ++P+L G P++ A A
Sbjct: 674 KSSPQPQQTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTLH---GSPSAKAKQPPE-A 726
Query: 326 SSWESEAAP-EPAAPPA---APSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPP 381
S A P EP+ P AP D P + ++VK T L ++ P
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP---------TTDLVSSSSATTKPD 777
Query: 382 LTRGRSVEQSPPRERPRAAGRRGRMAEA---SGRRGSPRARKA-SRSQSETSLL---GRA 434
+ + Q+ + P + +++ +G + SP KA R S++ ++ G +
Sbjct: 778 IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS 837
Query: 435 SAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCR--RWRSTA-EIDAADGRRVR 491
S P ++EEP+ + + P P GS R TA + + +
Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK 897
Query: 492 PRAPAAR--------VPGPGPSPSAPQRRL---LYG------CAGSDSECSAGRLGPLGR 534
P+ + R P P+ PQ + L+G S+ +AG+ GP +
Sbjct: 898 PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ 957
Query: 535 RGPAGGVGGGYGESESSASEG 555
GP + S+ S+G
Sbjct: 958 SGPGAPMKQAPAPSQPPTSQG 978
Score = 33.9 bits (76), Expect = 0.47
Identities = 49/216 (22%), Positives = 74/216 (34%), Gaps = 20/216 (9%)
Query: 266 GQPRTSPGGADGGPRRQNSVRQRPPDASPSP-GSARP--AREPSLERVGGHPTSPAALSR 322
GQ + P P++ + PDA P P GS P R + + V SP +
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
Query: 323 AWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQA----ATRGLP------G 372
+ S + + AP + P+ P G+L +QA +T G P G
Sbjct: 902 SRRFSLNLGSITD--APKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959
Query: 373 RAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLG 432
A K P Q PP+ +A + +P A K + +
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 433 RASAVPSGPP----KYPTAEREEP-RPPRPRRGPAP 463
R PP K TAE ++ P + + P P
Sbjct: 1020 RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP 1055
Score = 32.3 bits (72), Expect = 1.4
Identities = 95/433 (21%), Positives = 148/433 (34%), Gaps = 67/433 (15%)
Query: 98 GDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGI 157
G + + G + S + +G + PS GP PP G + PS+ G
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG- 505
Query: 158 YASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLT 217
P+ G A PS P+ G+ + P GSA P SA++ + A P
Sbjct: 506 STKPPPQQPGPAKPS-PQQPGS--------TKPPSQQPGSAKP----SAQQPSPAKPSAQ 552
Query: 218 PSPLHAVAMRSPRPCGRPPTDSPDAGGAGR--------PLDGYISALLRRRRRRG----- 264
S S +P +PPT SP A PL LL +
Sbjct: 553 QSTKPVSQTGSGKPL-QPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 265 -AGQPRTSPGGADGGPRRQ--------NSVRQRPPDASPSPGSARPAREPSLERVGGHPT 315
S G + P N +R +P + P +P L+ T
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTTT 669
Query: 316 SPAALS--RAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGR 373
S + S + +S + +AAP+ AP P P LVK Q G P
Sbjct: 670 SAVSKSSPQPQQTSPKKDAAPKQDL-SKAPEPKKPPP---LVK-------QPTLHGSP-- 716
Query: 374 AARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGR 433
+A+ K PP S+ + P + P + + A + P+ K + +S
Sbjct: 717 SAKAKQPP--EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 434 ASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRV-RP 492
+PS K + E+ PP P+ + G ++ D + + RP
Sbjct: 775 KPDIPSS--KVQSQAEEKTTPPLKTDSAKPSQSFPPTGE--------KVSPFDSKAIPRP 824
Query: 493 RAPAARVPGPGPS 505
+ + + PGPS
Sbjct: 825 ASDSKIISHPGPS 837
Score = 31.6 bits (70), Expect = 2.3
Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 296 PGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSP 349
P S P+ PS+ + P P R+ + ++ P P PP P PP P
Sbjct: 2372 PASQLPSGSPSVSSL---PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Score = 30.8 bits (68), Expect = 3.9
Identities = 47/193 (24%), Positives = 71/193 (36%), Gaps = 23/193 (11%)
Query: 220 PLHAVAMRSPRPCGRP-PTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSP--GGAD 276
P A SP+P +P P SP G RP G ++ + R S G
Sbjct: 855 PKKAQTKMSPKPDAKPMPKGSPTPPGP-RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 277 GGPRRQNSVRQRPPDASPSP-GSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE 335
P+ Q + Q G++ ++ +L G P P + S A + AP
Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP-GPHSQSGPGAPM---KQAPA 969
Query: 336 PAAPPAAPSPPDSPAEGRLVKAQYIP-----GAQAATRGLP---------GRAARRKPPP 381
P+ PP + PP S + A+ IP A AA + P +KPPP
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Query: 382 LTRGRSVEQSPPR 394
+ +S+ P +
Sbjct: 1030 IKDSKSLTAEPQK 1042
Score = 30.0 bits (66), Expect = 6.7
Identities = 13/24 (54%), Positives = 17/24 (70%)
Query: 576 PQQLVAATAASGGGAGAGAPAGPA 599
P+ L AA AA GG +GAG+P+ A
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTA 36
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,158,273
Number of Sequences: 37866
Number of extensions: 2361077
Number of successful extensions: 28918
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 300
Number of HSP's successfully gapped in prelim test: 2471
Number of HSP's that attempted gapping in prelim test: 16072
Number of HSP's gapped (non-prelim): 10782
length of query: 629
length of database: 18,247,518
effective HSP length: 108
effective length of query: 521
effective length of database: 14,157,990
effective search space: 7376312790
effective search space used: 7376312790
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.