Search of human proteins with 170671732

Search of human proteins with 170671732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170671732 melanocortin 3 receptor [Homo sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170671732 melanocortin 3 receptor [Homo sapiens]                   654   0.0  
gi|5174535 melanocortin 5 receptor [Homo sapiens]                     393   e-109
gi|119508433 melanocortin 4 receptor [Homo sapiens]                   382   e-106
gi|193083134 melanocortin 1 receptor [Homo sapiens]                   286   2e-77
gi|4505127 melanocortin 2 receptor [Homo sapiens]                     279   2e-75
gi|134244587 endothelial differentiation, sphingolipid G-protein...   127   1e-29
gi|4885295 G protein-coupled receptor 12 [Homo sapiens]               123   2e-28
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]           122   3e-28
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]           122   3e-28
gi|4885325 G protein-coupled receptor 3 [Homo sapiens]                112   4e-25
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]         111   8e-25
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]         105   5e-23
gi|5921992 adenosine A2a receptor [Homo sapiens]                      105   7e-23
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]            105   7e-23
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]            103   2e-22
gi|4885341 G protein-coupled receptor 6 [Homo sapiens]                 98   1e-20
gi|13540517 endothelial differentiation, sphingolipid G-protein-...    96   3e-20
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]           94   2e-19
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]           94   2e-19
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]           94   2e-19
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]           94   2e-19
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]            94   2e-19
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]           94   2e-19
gi|115305569 adenosine A1 receptor [Homo sapiens]                      93   4e-19
gi|4501947 adenosine A1 receptor [Homo sapiens]                        93   4e-19
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]              85   1e-16
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]       84   2e-16
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]            84   2e-16
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]             84   2e-16
gi|150170722 G protein-coupled receptor 50 [Homo sapiens]              84   2e-16

>gi|170671732 melanocortin 3 receptor [Homo sapiens]
          Length = 323

 Score =  654 bits (1686), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI 60
           MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI
Sbjct: 1   MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI 60

Query: 61  LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF 120
           LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF
Sbjct: 61  LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF 120

Query: 121 DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI 180
           DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI
Sbjct: 121 DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI 180

Query: 181 VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG 240
           VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG
Sbjct: 181 VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG 240

Query: 241 AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA 300
           AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
Sbjct: 241 AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA 300

Query: 301 FRSLELRNTFREILCGCNGMNLG 323
           FRSLELRNTFREILCGCNGMNLG
Sbjct: 301 FRSLELRNTFREILCGCNGMNLG 323


>gi|5174535 melanocortin 5 receptor [Homo sapiens]
          Length = 325

 Score =  393 bits (1009), Expect = e-109
 Identities = 197/322 (61%), Positives = 250/322 (77%), Gaps = 5/322 (1%)

Query: 1   MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI 60
           MN+S  L  +   L     +L  P   N+SS   CE + I  EVFL+LG++SLLENILVI
Sbjct: 1   MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSP--CEDMGIAVEVFLTLGVISLLENILVI 58

Query: 61  LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF 120
            A+V+N NLHSPMYFF+CSLAVADMLVS+S+A ETI I ++++ +L   D F++H+DN+F
Sbjct: 59  GAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVF 118

Query: 121 DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI 180
           DSMICIS+VAS+C+LLAIAVDRYVTIFYALRYH IMT R++  +I  IW  C  CG+VFI
Sbjct: 119 DSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFI 178

Query: 181 VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG 240
           +YSES  VI+CLI+MFFAM+ L+ +LY+HMFL AR HVKRIAALP A   + +Q + M+G
Sbjct: 179 LYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGAS--SARQRTSMQG 236

Query: 241 AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA 300
           AVT+T+LLGVF  CWAPFFLHL L+++CP N YC  + +HFN YL+LIMCNSV+DPLIYA
Sbjct: 237 AVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYA 296

Query: 301 FRSLELRNTFREILCGCNGMNL 322
           FRS E+R TF+EI+C C G  +
Sbjct: 297 FRSQEMRKTFKEIIC-CRGFRI 317


>gi|119508433 melanocortin 4 receptor [Homo sapiens]
          Length = 332

 Score =  382 bits (980), Expect = e-106
 Identities = 184/300 (61%), Positives = 235/300 (78%), Gaps = 7/300 (2%)

Query: 16  NGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYF 75
           N SE L   +    S     EQ+F+ PEVF++LG++SLLENILVI+A+ +N NLHSPMYF
Sbjct: 26  NASESLGKGY----SDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYF 81

Query: 76  FLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNL 135
           F+CSLAVADMLVSVSN  ETI+I +++S   T    F  ++DN+ DS+IC SL+ASIC+L
Sbjct: 82  FICSLAVADMLVSVSNGSETIVITLLNSTD-TDAQSFTVNIDNVIDSVICSSLLASICSL 140

Query: 136 LAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITM 195
           L+IAVDRY TIFYAL+YH+IMTV++   +I  IW  C V G++FI+YS+S  VI+CLITM
Sbjct: 141 LSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITM 200

Query: 196 FFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCW 255
           FF M+ LM +LYVHMFL ARLH+KRIA LP    +  +Q + MKGA+T+TIL+GVF+ CW
Sbjct: 201 FFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAI--RQGANMKGAITLTILIGVFVVCW 258

Query: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
           APFFLHL+  I+CP NPYC+C+ +HFN YL+LIMCNS+IDPLIYA RS ELR TF+EI+C
Sbjct: 259 APFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIIC 318


>gi|193083134 melanocortin 1 receptor [Homo sapiens]
          Length = 317

 Score =  286 bits (732), Expect = 2e-77
 Identities = 142/284 (50%), Positives = 192/284 (67%), Gaps = 1/284 (0%)

Query: 31  SSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVS 90
           + A C +V I   +FLSLG+VSL+EN LV+  + +N NLHSPMY F+C LA++D+LVS S
Sbjct: 31  TGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGS 90

Query: 91  NALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYAL 150
           N LET +I ++ +  L      +Q +DN+ D + C S+++S+C L AIAVDRY++IFYAL
Sbjct: 91  NVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYAL 150

Query: 151 RYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHM 210
           RYHSI+T+ +A   + AIWV   V   +FI Y +   V++CL+  F AM++LM  LYVHM
Sbjct: 151 RYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHM 210

Query: 211 FLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT 270
              A  H + IA L        Q    +KGAVT+TILLG+F  CW PFFLHL LI+ CP 
Sbjct: 211 LARACQHAQGIARLHKRQRPVHQGFG-LKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPE 269

Query: 271 NPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREIL 314
           +P C C   +FN +L LI+CN++IDPLIYAF S ELR T +E+L
Sbjct: 270 HPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVL 313


>gi|4505127 melanocortin 2 receptor [Homo sapiens]
          Length = 297

 Score =  279 bits (714), Expect = 2e-75
 Identities = 133/280 (47%), Positives = 193/280 (68%), Gaps = 9/280 (3%)

Query: 35  CEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALE 94
           C +V +  E+F ++ IV +LEN++V+LAV +N NL +PMYFF+CSLA++DML S+   LE
Sbjct: 21  CPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILE 80

Query: 95  TIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHS 154
            I+I + +  YL     F    D+I DS+  +SL+ SI +L  IA DRY+TIF+ALRYHS
Sbjct: 81  NILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHS 140

Query: 155 IMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFA 214
           I+T+R+ + ++  IW  C   G+  +++S     ++   ++F  M++ +  LYVHMFL A
Sbjct: 141 IVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLA 200

Query: 215 RLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYC 274
           R H ++I+ LP A+         MKGA+T+TILLGVFIFCWAPF LH++L+  CP+NPYC
Sbjct: 201 RSHTRKISTLPRAN---------MKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYC 251

Query: 275 ICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREIL 314
            CY + F    +LIMCN+VIDP IYAFRS ELR+ F++++
Sbjct: 252 ACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMI 291


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score =  127 bits (320), Expect = 1e-29
 Identities = 103/304 (33%), Positives = 153/304 (50%), Gaps = 51/304 (16%)

Query: 27  SNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADML 86
           S Q +SAF         V L   IV  +EN+LV++AV RN   HS MY FL +LA +D+L
Sbjct: 32  SRQVASAFI--------VILCCAIV--VENLLVLIAVARNSKFHSAMYLFLGNLAASDLL 81

Query: 87  VSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTI 146
             V+    T++   V +  LT    F +      +    I+L AS+ +LLAIA++R+V I
Sbjct: 82  AGVAFVANTLLSGSV-TLRLTPVQWFAR------EGSAFITLSASVFSLLAIAIERHVAI 134

Query: 147 FYALRYHSIMTVRKALT-------------LIVAIWVCCG---VCGVVFIVYSESKMVIV 190
                Y S  + R  L              L +  W C G    C  V  +Y  +K  ++
Sbjct: 135 AKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLY--AKHYVL 192

Query: 191 CLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGV 250
           C++T+F  ++L +  LYV ++   R           AD  APQ  + +K   T+TI+LGV
Sbjct: 193 CVVTIFSIILLAIVALYVRIYCVVR--------SSHADMAAPQTLALLK---TVTIVLGV 241

Query: 251 FIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTF 310
           FI CW P F  L+L   CP +   I Y AH+  +  +   NS+++P+IY +RS +LR   
Sbjct: 242 FIVCWLPAFSILLLDYACPVHSCPILYKAHY--FFAVSTLNSLLNPVIYTWRSRDLR--- 296

Query: 311 REIL 314
           RE+L
Sbjct: 297 REVL 300


>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
          Length = 334

 Score =  123 bits (309), Expect = 2e-28
 Identities = 94/326 (28%), Positives = 148/326 (45%), Gaps = 48/326 (14%)

Query: 19  EHLQAPFFSNQSSSAFCEQVFIKPE----------VFLSLGIVSLLENILVILAVVRNGN 68
           ++L A    N S++       ++PE          V  + G +   EN +V+L +  N +
Sbjct: 15  DYLDAAAAENISAAVSSRVPAVEPEPELVVNPWDIVLCTSGTLISCENAIVVLIIFHNPS 74

Query: 69  LHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISL 128
           L +PM+  + SLA+AD+L  +      +   ++ S+              +   +I  S 
Sbjct: 75  LRAPMFLLIGSLALADLLAGIGLITNFVFAYLLQSEATKL----------VTIGLIVASF 124

Query: 129 VASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIW---VCCGVCGVV------- 178
            AS+C+LLAI VDRY++++YAL YHS  TV     ++V +W   +C G+  V+       
Sbjct: 125 SASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVMGWNCLRD 184

Query: 179 ----FIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQ 234
                +V   +K     L   F  M  LM  LY+ +      H  +I AL          
Sbjct: 185 ESTCSVVRPLTKNNAAILSVSFLFMFALMLQLYIQICKIVMRHAHQI-ALQHHFLATSHY 243

Query: 235 HSCMKGAVTITILLGVFIFCWAPFFLH-LVLIITCPTNPYCICYTAHFNTYLVLIMC--N 291
            +  KG  T+ I+LG F  CW PF L+ L+   T P+            TY  L+    N
Sbjct: 244 VTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPS----------IYTYATLLPATYN 293

Query: 292 SVIDPLIYAFRSLELRNTFREILCGC 317
           S+I+P+IYAFR+ E++     I CGC
Sbjct: 294 SIINPVIYAFRNQEIQKALCLICCGC 319


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  122 bits (307), Expect = 3e-28
 Identities = 88/312 (28%), Positives = 152/312 (48%), Gaps = 37/312 (11%)

Query: 25  FFSNQSSSAFCEQVFIKPEVFLSLGIVS----LLENILVILAVVRNGNLHSPMYFFLCSL 80
           FF N+S      +     ++ + LGI      +L N+LV++A+  N   H P+Y+ + +L
Sbjct: 32  FFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANL 91

Query: 81  AVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAV 140
           A AD    ++     +     ++  LT     ++        +I  SL AS+ NLLAIA+
Sbjct: 92  AAADFFAGLAY-FYLMFNTGPNTRRLTVSTWLLRQ------GLIDTSLTASVANLLAIAI 144

Query: 141 DRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIV-----------------YS 183
           +R++T+F  ++ H+ M+ R+ + +IV IW    V G +  V                 YS
Sbjct: 145 ERHITVF-RMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYS 203

Query: 184 ESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVT 243
           +S +V   +  +     ++M  LY H+F + R    R++    + G    + + M    T
Sbjct: 204 DSYLVFWAIFNL--VTFVVMVVLYAHIFGYVRQRTMRMSR--HSSGPRRNRDTMMSLLKT 259

Query: 244 ITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRS 303
           + I+LG FI CW P  + L+L + CP         A+   +L+L   NS ++P+IY++R 
Sbjct: 260 VVIVLGAFIICWTPGLVLLLLDVCCPQCDVL----AYEKFFLLLAEFNSAMNPIIYSYRD 315

Query: 304 LELRNTFREILC 315
            E+  TFR+ILC
Sbjct: 316 KEMSATFRQILC 327


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  122 bits (307), Expect = 3e-28
 Identities = 88/312 (28%), Positives = 152/312 (48%), Gaps = 37/312 (11%)

Query: 25  FFSNQSSSAFCEQVFIKPEVFLSLGIVS----LLENILVILAVVRNGNLHSPMYFFLCSL 80
           FF N+S      +     ++ + LGI      +L N+LV++A+  N   H P+Y+ + +L
Sbjct: 32  FFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANL 91

Query: 81  AVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAV 140
           A AD    ++     +     ++  LT     ++        +I  SL AS+ NLLAIA+
Sbjct: 92  AAADFFAGLAY-FYLMFNTGPNTRRLTVSTWLLRQ------GLIDTSLTASVANLLAIAI 144

Query: 141 DRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIV-----------------YS 183
           +R++T+F  ++ H+ M+ R+ + +IV IW    V G +  V                 YS
Sbjct: 145 ERHITVF-RMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYS 203

Query: 184 ESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVT 243
           +S +V   +  +     ++M  LY H+F + R    R++    + G    + + M    T
Sbjct: 204 DSYLVFWAIFNL--VTFVVMVVLYAHIFGYVRQRTMRMSR--HSSGPRRNRDTMMSLLKT 259

Query: 244 ITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRS 303
           + I+LG FI CW P  + L+L + CP         A+   +L+L   NS ++P+IY++R 
Sbjct: 260 VVIVLGAFIICWTPGLVLLLLDVCCPQCDVL----AYEKFFLLLAEFNSAMNPIIYSYRD 315

Query: 304 LELRNTFREILC 315
            E+  TFR+ILC
Sbjct: 316 KEMSATFRQILC 327


>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
          Length = 330

 Score =  112 bits (280), Expect = 4e-25
 Identities = 85/297 (28%), Positives = 134/297 (45%), Gaps = 50/297 (16%)

Query: 49  GIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTF 108
           G +   EN LV+  +V      +PM+  + SLAVAD+L  +   L    +  + S     
Sbjct: 51  GTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGS----- 105

Query: 109 EDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLI--- 165
                  M  +   ++ ++  ASI +LLAI VDRY++++ AL Y+S  TV +   ++   
Sbjct: 106 -----AEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALV 160

Query: 166 -----------VAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFA 214
                      V  W C        +VY  SK  +V L   FF +  +M  LY  +    
Sbjct: 161 WGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIV 220

Query: 215 RLHVKRIA----ALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT 270
             H ++IA     LP +  VA +     KG  T+ ++LG F  CW PF +          
Sbjct: 221 CRHAQQIALQRHLLPASHYVATR-----KGIATLAVVLGAFAACWLPFTV---------- 265

Query: 271 NPYCICYTAH---FNTYLVLIMC--NSVIDPLIYAFRSLELRNTFREILCGCNGMNL 322
             YC+   AH     TYL L+    NS+I+P+IYAFR+ +++     + C C+   +
Sbjct: 266 --YCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCCSSSKI 320


>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
          Length = 382

 Score =  111 bits (278), Expect = 8e-25
 Identities = 79/291 (27%), Positives = 139/291 (47%), Gaps = 29/291 (9%)

Query: 44  VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHS 103
           VF+ +    +LENI V+L + +    H PMY+F+ +LA++D+L  V+     ++++   +
Sbjct: 51  VFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYT-ANLLLSGATT 109

Query: 104 DYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALT 163
             LT    F++      +  + ++L AS+ +LLAIA++RY+T+   ++ H+     +   
Sbjct: 110 YKLTPAQWFLR------EGSMFVALSASVFSLLAIAIERYITML-KMKLHNGSNNFRLFL 162

Query: 164 LIVAIWV-----------------CCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTL 206
           LI A WV                     C  V  +Y   K  I+   T+F  ++L +  L
Sbjct: 163 LISACWVISLILGGLPIMGWNCISALSSCSTVLPLY--HKHYILFCTTVFTLLLLSIVIL 220

Query: 207 YVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLII 266
           Y  ++   R   +R+         +      +    T+ I+L VFI CWAP F+ L+L +
Sbjct: 221 YCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV 280

Query: 267 TCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGC 317
            C      I + A +  +LVL + NS  +P+IY   + E+R  F  I+  C
Sbjct: 281 GCKVKTCDILFRAEY--FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCC 329


>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
          Length = 378

 Score =  105 bits (262), Expect = 5e-23
 Identities = 73/289 (25%), Positives = 140/289 (48%), Gaps = 32/289 (11%)

Query: 44  VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHS 103
           +FL +    +LEN++V++A+ +N   H+ MYFF+ +LA+ D+L  ++  +  +M     S
Sbjct: 45  LFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILM-----S 99

Query: 104 DYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALT 163
              TF       +  + +  + ++L AS C+LLAIA++R++T+   +R +      +   
Sbjct: 100 GKKTF--SLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMI-KMRPYDANKRHRVFL 156

Query: 164 LIVAIWVCCGVCGVV---------------FIVYSESKMVIVCLITMFFAMMLLMGTLYV 208
           LI   W+     G +                I+   SK  I   I++F A+++ +  LY 
Sbjct: 157 LIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYA 216

Query: 209 HMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITC 268
            ++   +   +++A               M    T+ I++ VFI CW+P F+  ++ + C
Sbjct: 217 RIYFLVKSSSRKVAN-------HNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVAC 269

Query: 269 PTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGC 317
                 I + A +  ++VL + NS ++P+IY   S E+R  F  ++C C
Sbjct: 270 RVQACPILFKAQW--FIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNC 316


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score =  105 bits (261), Expect = 7e-23
 Identities = 89/308 (28%), Positives = 144/308 (46%), Gaps = 53/308 (17%)

Query: 44  VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHS 103
           V L++ ++++L N+LV  AV  N NL +   +F+ SLA AD+ V V        +AI  +
Sbjct: 12  VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV--------LAIPFA 63

Query: 104 DYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALT 163
             ++       H        + +   +SI +LLAIA+DRY+ I   LRY+ ++T  +A  
Sbjct: 64  ITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKG 123

Query: 164 LIVAIWVC---------------------------CGVCGVVFIVYSESKMVIVCLITMF 196
           +I   WV                            CG  G V  ++ +   +   +   F
Sbjct: 124 IIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGE-GQVACLFEDVVPMNYMVYFNF 182

Query: 197 FAM----MLLMGTLYVHMFLFARLHVKRIAALP-PADGVAPQQHSCMKGAVTITILLGVF 251
           FA     +LLM  +Y+ +FL AR  +K++ + P P +         +  A ++ I++G+F
Sbjct: 183 FACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLF 242

Query: 252 IFCWAPFFLHLVLIIT-----CPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLEL 306
             CW P  LH++   T     C   P  + Y A     +VL   NSV++P IYA+R  E 
Sbjct: 243 ALCWLP--LHIINCFTFFCPDCSHAPLWLMYLA-----IVLSHTNSVVNPFIYAYRIREF 295

Query: 307 RNTFREIL 314
           R TFR+I+
Sbjct: 296 RQTFRKII 303


>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
          Length = 351

 Score =  105 bits (261), Expect = 7e-23
 Identities = 88/314 (28%), Positives = 148/314 (47%), Gaps = 40/314 (12%)

Query: 25  FFSNQSSSAFCEQVFIKPEVFLSLG----IVSLLENILVILAVVRNGNLHSPMYFFLCSL 80
           FF N S          K  V ++LG    ++ LL N+LVI A+  N   H P+Y+ L +L
Sbjct: 15  FFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNL 74

Query: 81  AVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAV 140
           A AD+   V+  L  +      +  L+ E  F++        ++  SL AS+  LLAIAV
Sbjct: 75  AAADLFAGVA-YLFLMFHTGPRTARLSLEGWFLR------QGLLDTSLTASVATLLAIAV 127

Query: 141 DRYVTIFYALRYHSIMTVRKALTLIVAIWVC---------------CGV--CGVVFIVYS 183
           +R+ ++  A++ HS +   + + LIV +WV                C +  C  +  + S
Sbjct: 128 ERHRSVM-AVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLS 186

Query: 184 ESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVT 243
            S + +  L ++   + LLM  +Y  +F + R  V+R+A           + + +    T
Sbjct: 187 RSYLAVWALSSLL--VFLLMVAVYTRIFFYVRRRVQRMAEHVSCH--PRYRETTLSLVKT 242

Query: 244 ITILLGVFIFCWAPFFLHLVLI-ITCPTNPYCICYTAHFNTY-LVLIMCNSVIDPLIYAF 301
           + I+LG F+ CW P  + L+L  + C +     C       Y L+L   NS+++  +Y+ 
Sbjct: 243 VVIILGAFVVCWTPGQVVLLLDGLGCES-----CNVLAVEKYFLLLAEANSLVNAAVYSC 297

Query: 302 RSLELRNTFREILC 315
           R  E+R TFR +LC
Sbjct: 298 RDAEMRRTFRRLLC 311


>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
          Length = 353

 Score =  103 bits (257), Expect = 2e-22
 Identities = 76/279 (27%), Positives = 136/279 (48%), Gaps = 36/279 (12%)

Query: 56  NILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQH 115
           N LVI AV++N   H P Y+ L +LA AD    ++          V S  LT    F++ 
Sbjct: 48  NSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPV-SKTLTVNRWFLR- 105

Query: 116 MDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV----- 170
              + DS    SL AS+ NLL IAV+R+++I   +R HS +T ++   LI+ +W      
Sbjct: 106 -QGLLDS----SLTASLTNLLVIAVERHMSIM-RMRVHSNLTKKRVTLLILLVWAIAIFM 159

Query: 171 ----------CCGV--CGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHV 218
                      C +  C  +  +YS S +V   +  +     L+M  +Y+ ++++ +   
Sbjct: 160 GAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLM--AFLIMVVVYLRIYVYVKRKT 217

Query: 219 KRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLI-ITCPTNPYCICY 277
             ++  P   G   ++ + MK   T+  +LG F+ CW P  + L+L  + C       C 
Sbjct: 218 NVLS--PHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQ-----CG 270

Query: 278 TAHFNT-YLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
             H    +L+L + NSV++P+IY+++  ++  T ++++C
Sbjct: 271 VQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMIC 309


>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
          Length = 362

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 78/283 (27%), Positives = 124/283 (43%), Gaps = 32/283 (11%)

Query: 49  GIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTF 108
           G V   EN LV+  +     L +PM+  + SLA AD+L      L  +   +V S+ ++ 
Sbjct: 83  GTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSL 142

Query: 109 EDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAI 168
                     +    +  S  AS+ +LLAI VDRY++++ AL Y+S  T+     L+ A 
Sbjct: 143 ----------LTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAAT 192

Query: 169 WV--------------CCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFA 214
           W               C        +V   ++  +  L   FF +  +M  LYV +    
Sbjct: 193 WTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVV 252

Query: 215 RLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYC 274
             H  +I AL       P   +  KG  T+ ++LG F   W PF ++ V  +    +P  
Sbjct: 253 WRHAHQI-ALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCV--VGSHEDPAV 309

Query: 275 ICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGC 317
             Y       L+    NS+I+P+IYAFR+ E++     +LCGC
Sbjct: 310 YTYAT-----LLPATYNSMINPIIYAFRNQEIQRALWLLLCGC 347


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 76/295 (25%), Positives = 145/295 (49%), Gaps = 37/295 (12%)

Query: 44  VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIM---IAI 100
           V L++    +LEN+ V+L + R+   H+PM+  L SL ++D+L   + A   ++   + +
Sbjct: 42  VCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTL 101

Query: 101 VHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIF------YALRYHS 154
             S  L F            +  + ++L AS+ +LLAIA++R +T+        + R  +
Sbjct: 102 KLSPALWFAR----------EGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRT 151

Query: 155 IMTVRKA------LTLIVAI-WVCCG---VCGVVFIVYSESKMVIVCLITMFFAMMLLMG 204
           +     A      L L+ A+ W C G    C  V  +Y+++  V+ C++  F  ++  + 
Sbjct: 152 LAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKA-YVLFCVLA-FVGILAAIC 209

Query: 205 TLYVHMFLFARLHVKRIAALPPADGV----APQQHSCMKGAVTITILLGVFIFCWAPFFL 260
            LY  ++   R + +R+ A P   G     A ++   +    T++++L  F+ CW P FL
Sbjct: 210 ALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFL 269

Query: 261 HLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
            L+L + CP     +   A  + +L L M NS+++P+IY   + +LR+    ++C
Sbjct: 270 LLLLDVACPARTCPVLLQA--DPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVC 322


>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)

Query: 46  LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104
           L+LG  ++LEN+LV+  ++ + +L   P Y F+ SLAVAD+L SV      I   + H  
Sbjct: 124 LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 183

Query: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164
                + F+  +  +       S  AS+ +L   A+DRY++I   L Y  I+T  KA+  
Sbjct: 184 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211
              +W    V  V+ ++ ++  K+  VC            MF+     +LL+  +Y +M+
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255
           +  + H   +  +      +   H+   G V +T                ++L V I CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
            P    +V  +    N       A  +   +L + NS ++P+IYA RS +LR+ FR +  
Sbjct: 357 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 316 GCNG 319
            C G
Sbjct: 414 SCEG 417


>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)

Query: 46  LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104
           L+LG  ++LEN+LV+  ++ + +L   P Y F+ SLAVAD+L SV      I   + H  
Sbjct: 124 LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 183

Query: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164
                + F+  +  +       S  AS+ +L   A+DRY++I   L Y  I+T  KA+  
Sbjct: 184 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211
              +W    V  V+ ++ ++  K+  VC            MF+     +LL+  +Y +M+
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255
           +  + H   +  +      +   H+   G V +T                ++L V I CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
            P    +V  +    N       A  +   +L + NS ++P+IYA RS +LR+ FR +  
Sbjct: 357 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 316 GCNG 319
            C G
Sbjct: 414 SCEG 417


>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)

Query: 46  LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104
           L+LG  ++LEN+LV+  ++ + +L   P Y F+ SLAVAD+L SV      I   + H  
Sbjct: 124 LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 183

Query: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164
                + F+  +  +       S  AS+ +L   A+DRY++I   L Y  I+T  KA+  
Sbjct: 184 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211
              +W    V  V+ ++ ++  K+  VC            MF+     +LL+  +Y +M+
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255
           +  + H   +  +      +   H+   G V +T                ++L V I CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
            P    +V  +    N       A  +   +L + NS ++P+IYA RS +LR+ FR +  
Sbjct: 357 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 316 GCNG 319
            C G
Sbjct: 414 SCEG 417


>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)

Query: 46  LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104
           L+LG  ++LEN+LV+  ++ + +L   P Y F+ SLAVAD+L SV      I   + H  
Sbjct: 124 LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 183

Query: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164
                + F+  +  +       S  AS+ +L   A+DRY++I   L Y  I+T  KA+  
Sbjct: 184 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211
              +W    V  V+ ++ ++  K+  VC            MF+     +LL+  +Y +M+
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255
           +  + H   +  +      +   H+   G V +T                ++L V I CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
            P    +V  +    N       A  +   +L + NS ++P+IYA RS +LR+ FR +  
Sbjct: 357 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 316 GCNG 319
            C G
Sbjct: 414 SCEG 417


>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)

Query: 46  LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104
           L+LG  ++LEN+LV+  ++ + +L   P Y F+ SLAVAD+L SV      I   + H  
Sbjct: 124 LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 183

Query: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164
                + F+  +  +       S  AS+ +L   A+DRY++I   L Y  I+T  KA+  
Sbjct: 184 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211
              +W    V  V+ ++ ++  K+  VC            MF+     +LL+  +Y +M+
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255
           +  + H   +  +      +   H+   G V +T                ++L V I CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
            P    +V  +    N       A  +   +L + NS ++P+IYA RS +LR+ FR +  
Sbjct: 357 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 316 GCNG 319
            C G
Sbjct: 414 SCEG 417


>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
          Length = 439

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)

Query: 46  LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104
           L+LG  ++LEN+LV+  ++ + +L   P Y F+ SLAVAD+L SV      I   + H  
Sbjct: 91  LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 150

Query: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164
                + F+  +  +       S  AS+ +L   A+DRY++I   L Y  I+T  KA+  
Sbjct: 151 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 203

Query: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211
              +W    V  V+ ++ ++  K+  VC            MF+     +LL+  +Y +M+
Sbjct: 204 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 263

Query: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255
           +  + H   +  +      +   H+   G V +T                ++L V I CW
Sbjct: 264 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 323

Query: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
            P    +V  +    N       A  +   +L + NS ++P+IYA RS +LR+ FR +  
Sbjct: 324 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 380

Query: 316 GCNG 319
            C G
Sbjct: 381 SCEG 384


>gi|115305569 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 88/318 (27%), Positives = 138/318 (43%), Gaps = 53/318 (16%)

Query: 30  SSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSV 89
           S SAF +  +I  EV ++L  VS+  N+LVI AV  N  L    + F+ SLAVAD+ V  
Sbjct: 4   SISAF-QAAYIGIEVLIAL--VSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60

Query: 90  SNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYA 149
                 I+I I    Y         H   +    + I   +SI  LLAIAVDRY+ +   
Sbjct: 61  LVIPLAILINIGPQTYF--------HTCLMVACPVLILTQSSILALLAIAVDRYLRVKIP 112

Query: 150 LRYHSIMTVRKALTLIVAIWVCCGVCGVVFI----------------------------- 180
           LRY  ++T R+A   I   W+   V G+  +                             
Sbjct: 113 LRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFE 172

Query: 181 -VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQH--SC 237
            V S   MV           +LLM  +Y+ +F   R  + +  +    D   PQ++    
Sbjct: 173 KVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGD---PQKYYGKE 229

Query: 238 MKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMC--NSVID 295
           +K A ++ ++L +F   W P  +   + + CP+     C+     TY+ + +   NS ++
Sbjct: 230 LKIAKSLALILFLFALSWLPLHILNCITLFCPS-----CHKPSILTYIAIFLTHGNSAMN 284

Query: 296 PLIYAFRSLELRNTFREI 313
           P++YAFR  + R TF +I
Sbjct: 285 PIVYAFRIQKFRVTFLKI 302


>gi|4501947 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 88/318 (27%), Positives = 138/318 (43%), Gaps = 53/318 (16%)

Query: 30  SSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSV 89
           S SAF +  +I  EV ++L  VS+  N+LVI AV  N  L    + F+ SLAVAD+ V  
Sbjct: 4   SISAF-QAAYIGIEVLIAL--VSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 60

Query: 90  SNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYA 149
                 I+I I    Y         H   +    + I   +SI  LLAIAVDRY+ +   
Sbjct: 61  LVIPLAILINIGPQTYF--------HTCLMVACPVLILTQSSILALLAIAVDRYLRVKIP 112

Query: 150 LRYHSIMTVRKALTLIVAIWVCCGVCGVVFI----------------------------- 180
           LRY  ++T R+A   I   W+   V G+  +                             
Sbjct: 113 LRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFE 172

Query: 181 -VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQH--SC 237
            V S   MV           +LLM  +Y+ +F   R  + +  +    D   PQ++    
Sbjct: 173 KVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGD---PQKYYGKE 229

Query: 238 MKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMC--NSVID 295
           +K A ++ ++L +F   W P  +   + + CP+     C+     TY+ + +   NS ++
Sbjct: 230 LKIAKSLALILFLFALSWLPLHILNCITLFCPS-----CHKPSILTYIAIFLTHGNSAMN 284

Query: 296 PLIYAFRSLELRNTFREI 313
           P++YAFR  + R TF +I
Sbjct: 285 PIVYAFRIQKFRVTFLKI 302


>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
          Length = 318

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 80/325 (24%), Positives = 144/325 (44%), Gaps = 61/325 (18%)

Query: 27  SNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADML 86
           +N ++ +     +I  E+F+  G+ +++ N+LVI  V  N +L +  ++F+ SLA+AD+ 
Sbjct: 3   NNSTALSLANVTYITMEIFI--GLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60

Query: 87  VSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLV---ASICNLLAIAVDRY 143
           V V      + +AIV S  +T     I     +F  M C+ L+   ASI +LLAIAVDRY
Sbjct: 61  VGVL----VMPLAIVVSLGIT-----IHFYSCLF--MTCLLLIFTHASIMSLLAIAVDRY 109

Query: 144 VTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI----------------------- 180
           + +   +RY  + T R+       IW+  G+C +V                         
Sbjct: 110 LRVKLTVRYKRVTTHRR-------IWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVT 162

Query: 181 --------VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAP 232
                   V     MV    +T  F  +++M  +Y+ +F   R  +    +     G   
Sbjct: 163 FLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFY 222

Query: 233 QQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNS 292
            +    K A ++ ++L +F   W P  +   +I      P  + Y       ++L   NS
Sbjct: 223 GRE--FKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMG-----ILLSHANS 275

Query: 293 VIDPLIYAFRSLELRNTFREILCGC 317
           +++P++YA++  + + T+  IL  C
Sbjct: 276 MMNPIVYAYKIKKFKETYLLILKAC 300


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 90/351 (25%), Positives = 154/351 (43%), Gaps = 66/351 (18%)

Query: 16  NGSEHLQAPFFSNQSSSAFCEQVFIKPEVFL-SLGIVSLL-------ENILVILAVVRNG 67
           NGS  L AP  S+       +Q   + EV++  +GIV  L        N+LVI A+ +  
Sbjct: 6   NGSAFLLAPNRSHAPDHDVTQQ---RDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFE 62

Query: 68  NLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICIS 127
            L +   +F+ SLA AD+++ +  A+     A +     TF + + +   +I   ++C++
Sbjct: 63  RLQTVTNYFITSLACADLVMGL--AVVPFGAAHILMKMWTFGNFWCEFWTSI--DVLCVT 118

Query: 128 LVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI------- 180
             ASI  L  IAVDRY  I    +Y S++T  KA  +I+ +W+  G+   + I       
Sbjct: 119 --ASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRA 176

Query: 181 ----------------VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFA---------- 214
                            ++     I   I  F+  +++M  +Y  +F  A          
Sbjct: 177 THQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKS 236

Query: 215 --RLHVKRIAALP----PADGVAPQQHSCM---KGAVTITILLGVFIFCWAPFFL-HLVL 264
             R HV+ ++ +        G+      C+   K   T+ I++G F  CW PFF+ ++V 
Sbjct: 237 EGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVH 296

Query: 265 IITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
           +I        +    ++  Y+     NS  +PLIY  RS + R  F+E+LC
Sbjct: 297 VIQDNLIRKEVYILLNWIGYV-----NSGFNPLIYC-RSPDFRIAFQELLC 341


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 78/313 (24%), Positives = 138/313 (44%), Gaps = 37/313 (11%)

Query: 28  NQSSSAFC-EQVFIKPEVFLSLGIVSLLE---NILVILAVVRNGNLHSPMYFFLCSLAVA 83
           N ++S+FC +    K  + + L ++ L+    N++V LAV  N  L +    F+ SLA+ 
Sbjct: 4   NGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAIT 63

Query: 84  DMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRY 143
           D+L+ +      +++       L+ +  F +   NI+ S+  +   ASI NL  I++DRY
Sbjct: 64  DLLLGL------LVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRY 117

Query: 144 VTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI---------------VYSESKMV 188
             +   LRY  ++T  +    +V IWV       + I                 S+ K+ 
Sbjct: 118 CAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQ 177

Query: 189 I------VCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAV 242
           +      V  +  F+  +L+M   Y  +F  AR   KRI  +        ++H   K  V
Sbjct: 178 VNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREH---KATV 234

Query: 243 TITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFR 302
           T+  ++G FI CW P+F   V       +       A     L L   NS ++P++YA  
Sbjct: 235 TLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEA---IVLWLGYANSALNPILYAAL 291

Query: 303 SLELRNTFREILC 315
           + + R  ++++ C
Sbjct: 292 NRDFRTGYQQLFC 304


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 78/313 (24%), Positives = 138/313 (44%), Gaps = 37/313 (11%)

Query: 28  NQSSSAFC-EQVFIKPEVFLSLGIVSLLE---NILVILAVVRNGNLHSPMYFFLCSLAVA 83
           N ++S+FC +    K  + + L ++ L+    N++V LAV  N  L +    F+ SLA+ 
Sbjct: 4   NGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAIT 63

Query: 84  DMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRY 143
           D+L+ +      +++       L+ +  F +   NI+ S+  +   ASI NL  I++DRY
Sbjct: 64  DLLLGL------LVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRY 117

Query: 144 VTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI---------------VYSESKMV 188
             +   LRY  ++T  +    +V IWV       + I                 S+ K+ 
Sbjct: 118 CAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQ 177

Query: 189 I------VCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAV 242
           +      V  +  F+  +L+M   Y  +F  AR   KRI  +        ++H   K  V
Sbjct: 178 VNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREH---KATV 234

Query: 243 TITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFR 302
           T+  ++G FI CW P+F   V       +       A     L L   NS ++P++YA  
Sbjct: 235 TLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEA---IVLWLGYANSALNPILYAAL 291

Query: 303 SLELRNTFREILC 315
           + + R  ++++ C
Sbjct: 292 NRDFRTGYQQLFC 304


>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
          Length = 617

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 72/283 (25%), Positives = 127/283 (44%), Gaps = 39/283 (13%)

Query: 50  IVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSV-SNALETIMIAIVHSDYLTF 108
           +V L+ N +VILAV +N  L +    F+ SL+VADMLV++    L    ++I   D    
Sbjct: 40  VVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQL 99

Query: 109 EDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAI 168
           + Q +  +  +       S+V SI N++AIA++RY  I ++L+Y  I +VR     +V  
Sbjct: 100 QCQMVGFITGL-------SVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVIT 152

Query: 169 WVCCGVC-------GVV---------FIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFL 212
           W+   +        G +            Y  + +  V ++ + F + LL     +  F 
Sbjct: 153 WIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLL-----IVGFC 207

Query: 213 FARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTN- 271
           + R+  K +AA  PA      Q + ++  +T+ ++  +F  CW P  +  VL+   P   
Sbjct: 208 YVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEM 267

Query: 272 ----PYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTF 310
               P  +   A+F  Y      NS ++ +IY   +   R  +
Sbjct: 268 AGKIPNWLYLAAYFIAYF-----NSCLNAVIYGLLNENFRREY 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.334    0.143    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,052,156
Number of Sequences: 37866
Number of extensions: 432818
Number of successful extensions: 3556
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 589
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 1782
Number of HSP's gapped (non-prelim): 1054
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.