Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 170650643
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170650643 solute carrier family 22, member 23 isoform a
[Homo sapiens]
(686 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 1403 0.0
gi|48526516 solute carrier family 22, member 23 isoform b [Homo ... 816 0.0
gi|21361834 solute carrier family 22, member 17 isoform a [Homo ... 261 2e-69
gi|63999576 solute carrier family 22, member 17 isoform b [Homo ... 261 2e-69
gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1... 260 3e-69
gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6... 248 1e-65
gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo sap... 153 6e-37
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 135 1e-31
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 132 8e-31
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 132 1e-30
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 130 4e-30
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 130 4e-30
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 127 4e-29
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 124 4e-28
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 121 2e-27
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 120 5e-27
gi|42542386 solute carrier family 22 (organic anion/cation trans... 119 7e-27
gi|157426885 organic cation transporter like 4 [Homo sapiens] 115 1e-25
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 115 2e-25
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 113 5e-25
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 112 1e-24
gi|166064021 solute carrier family 22 (organic anion transporter... 112 1e-24
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 110 4e-24
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 110 4e-24
gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 108 1e-23
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 108 2e-23
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 107 4e-23
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 99 1e-20
gi|153791484 putative UST1-like organic anion transporter [Homo ... 99 2e-20
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 87 4e-17
>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
sapiens]
Length = 686
Score = 1403 bits (3632), Expect = 0.0
Identities = 686/686 (100%), Positives = 686/686 (100%)
Query: 1 MAIDRRREAAGGGPGRQPAPAEENGSLPPGDAAASAPLGGRAGPGGGAEIQPLPPLHPGG 60
MAIDRRREAAGGGPGRQPAPAEENGSLPPGDAAASAPLGGRAGPGGGAEIQPLPPLHPGG
Sbjct: 1 MAIDRRREAAGGGPGRQPAPAEENGSLPPGDAAASAPLGGRAGPGGGAEIQPLPPLHPGG 60
Query: 61 GPHPSCCSAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFL 120
GPHPSCCSAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFL
Sbjct: 61 GPHPSCCSAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFL 120
Query: 121 LDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGG 180
LDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGG
Sbjct: 121 LDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGG 180
Query: 181 DTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGL 240
DTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGL
Sbjct: 181 DTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGL 240
Query: 241 IFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILT 300
IFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILT
Sbjct: 241 IFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILT 300
Query: 301 LYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYW 360
LYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYW
Sbjct: 301 LYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYW 360
Query: 361 SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVK 420
SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVK
Sbjct: 361 SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVK 420
Query: 421 VVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSC 480
VVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSC
Sbjct: 421 VVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSC 480
Query: 481 LAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAF 540
LAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAF
Sbjct: 481 LAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAF 540
Query: 541 SIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLH 600
SIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLH
Sbjct: 541 SIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLH 600
Query: 601 HIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQPLLLTNAELKD 660
HIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQPLLLTNAELKD
Sbjct: 601 HIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQPLLLTNAELKD 660
Query: 661 YSGLHDAAAAGDTLPEGATANGMKAM 686
YSGLHDAAAAGDTLPEGATANGMKAM
Sbjct: 661 YSGLHDAAAAGDTLPEGATANGMKAM 686
>gi|48526516 solute carrier family 22, member 23 isoform b [Homo
sapiens]
Length = 405
Score = 816 bits (2109), Expect = 0.0
Identities = 405/405 (100%), Positives = 405/405 (100%)
Query: 282 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 341
MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD
Sbjct: 1 MFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRD 60
Query: 342 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 401
WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV
Sbjct: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGV 120
Query: 402 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL 461
IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL
Sbjct: 121 IPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPL 180
Query: 462 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS 521
LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS
Sbjct: 181 LENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYS 240
Query: 522 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF 581
QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF
Sbjct: 241 QHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGF 300
Query: 582 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL 641
GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL
Sbjct: 301 GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPL 360
Query: 642 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM 686
LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM
Sbjct: 361 LPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM 405
>gi|21361834 solute carrier family 22, member 17 isoform a [Homo
sapiens]
Length = 538
Score = 261 bits (667), Expect = 2e-69
Identities = 165/491 (33%), Positives = 249/491 (50%), Gaps = 43/491 (8%)
Query: 187 SPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLI 246
+PPD N + WDY L N + +WDLVCD W+V + + ++G GYL
Sbjct: 63 APPD-----FNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
Query: 247 TGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRI 306
G AD GRR ++L ++ + G+ A + + T LRF GF LAG+ L +Y +R+
Sbjct: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
Query: 307 ELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY-W-SIFP 364
ELC P +R + + V + G FL GLA + +DW+ LQ +I P +L L Y W +F
Sbjct: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
Query: 365 ESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVC------- 417
ES RWL+ +Q E A+ ++ ++NR P G + G E +E + + C
Sbjct: 238 ESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG---EEAQEALQDLENTCPLPATSS 292
Query: 418 --IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASI 475
++ RN+WKN+++L + + I HC+ G +FY +
Sbjct: 293 FSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSP-----SDFYLCSLLASGT 347
Query: 476 ALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHP--------DSG 527
A ++C+ + V V GRRG LLL M LT +ASL+ LGL + +HP
Sbjct: 348 AALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWD-----CEHPIFPTVWAQQGN 402
Query: 528 MSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAP 587
+ + + FS++G+F+S A LS AE+ PT +R GLGL++A G L+ P
Sbjct: 403 PNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGP 462
Query: 588 IIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLL----P 643
LH G FL H++ A C L+CI+ I+LLPE++ + LPE + +GE R LL P
Sbjct: 463 AQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPP 522
Query: 644 HKKGEQPLLLT 654
+ PLL T
Sbjct: 523 TRCDHVPLLAT 533
>gi|63999576 solute carrier family 22, member 17 isoform b [Homo
sapiens]
Length = 520
Score = 261 bits (666), Expect = 2e-69
Identities = 164/483 (33%), Positives = 245/483 (50%), Gaps = 45/483 (9%)
Query: 187 SPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLI 246
+PPD N + WDY L N + +WDLVCD W+V + + ++G GYL
Sbjct: 63 APPD-----FNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
Query: 247 TGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRI 306
G AD GRR ++L ++ + G+ A + + T LRF GF LAG+ L +Y +R+
Sbjct: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
Query: 307 ELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY-W-SIFP 364
ELC P +R + + V + G FL GLA + +DW+ LQ +I P +L L Y W +F
Sbjct: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
Query: 365 ESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVC------- 417
ES RWL+ +Q E A+ ++ ++NR P G + G E +E + + C
Sbjct: 238 ESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG---EEAQEALQDLENTCPLPATSS 292
Query: 418 --IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASI 475
++ RN+WKN+++L + + I HC+ G +FY +
Sbjct: 293 FSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSP-----SDFYLCSLLASGT 347
Query: 476 ALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDK 535
A ++C+ + V V GRRG LLL M LT +ASL+ LGL D + +
Sbjct: 348 AALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLW---------------DYLNEA 392
Query: 536 FSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQK 595
FS++G+F+S A LS AE+ PT +R GLGL++A G L+ P LH
Sbjct: 393 AITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGH 452
Query: 596 GYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLL----PHKKGEQPL 651
G FL H++ A C L+CI+ I+LLPE++ + LPE + +GE R LL P + PL
Sbjct: 453 GAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPL 512
Query: 652 LLT 654
L T
Sbjct: 513 LAT 515
>gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1
[Homo sapiens]
Length = 558
Score = 260 bits (664), Expect = 3e-69
Identities = 186/575 (32%), Positives = 282/575 (49%), Gaps = 54/575 (9%)
Query: 78 LDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTEL 137
++ + VL GG G ++ L +W+P + +G S+ L QP CR T L
Sbjct: 1 MEQEARVLRAAGGFGRA-RRLLASASWVPCIVLGLVLSSEELLTAQPAPHCRP--DPTLL 57
Query: 138 AGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASN 197
RG + + ++P AP EA G S S A PL P AS
Sbjct: 58 PPALRALRGPALLD-AAIPRLGPTRAPAEALGVLSPSYLA------PLTRAPRPSSWAS- 109
Query: 198 CDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRR 257
C G AG W+LVC + WKV + + S L+G + G +I G D GRR
Sbjct: 110 CS------GAAAG------PTWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRR 157
Query: 258 PVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMI 317
V + S++ G + AL+ + LR G LAG +L LY R+ELC P R
Sbjct: 158 AVFVASLVLTTGLGASEALAASFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAF 217
Query: 318 TMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYW---SIFPESLRWLMATQ 374
+M A ++ G L+PGLAAL +DW++LQ L L+LL+W ++FPES WL+AT
Sbjct: 218 SMGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATG 277
Query: 375 QFESAKRLILHFTQKNRMNP-----EGDIKGVIPELEKELSR--RPKKVCIVKVVGTRNL 427
Q A++++ F + + + P E + EL +R +P+ + ++ TR
Sbjct: 278 QVARARKILWRFAEASGVGPGDSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVT 337
Query: 428 WKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVV 487
W+N ++L +SL G GI F RS+ P + FY Y+ A + + + + +
Sbjct: 338 WRNGLILGFSSLVGGGIRASFRRSL------APQVPTFYLPYFLEAGLEAAALVFLLLTA 391
Query: 488 RFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFA 547
GRR LLL ++T LASLL L + ++ + S++G+ A
Sbjct: 392 DCCGRRPVLLLGTMVTGLASLLLLAGAQYLPGWT---------------VLFLSVLGLLA 436
Query: 548 SHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACC 607
S AV +LS F AE+ PTVIR GLGLVL + G P+ LH ++G+FL ++FA
Sbjct: 437 SRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVVFASL 496
Query: 608 TLICIICILLLPESRDQNLPENISNGEHYTRQPLL 642
++ ++C+LLLPESR + LP+++ + + R PLL
Sbjct: 497 AVLALLCVLLLPESRSRGLPQSLQDADRLRRSPLL 531
>gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6
[Homo sapiens]
Length = 560
Score = 248 bits (634), Expect = 1e-65
Identities = 183/576 (31%), Positives = 278/576 (48%), Gaps = 54/576 (9%)
Query: 78 LDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTEL 137
++ + VL GG G ++ L +W+P + +G S+ L QP CR T L
Sbjct: 1 MEQEARVLRAAGGFGRA-RRLLASASWVPCIVLGLVLSSEELLTAQPAPHCRP--DPTLL 57
Query: 138 AGVTTTGRGGDMGNWTSLPTTPF-ATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNAS 196
RG + + P A +P G S S A PL P AS
Sbjct: 58 PPALRALRGPALLDAAIPRLGPTRAASPCLPLGVLSPSYLA------PLTRAPRPSSWAS 111
Query: 197 NCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGR 256
C G AG W+LVC + WKV + + S L+G + G +I G D GR
Sbjct: 112 -CS------GAAAG------PTWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGR 158
Query: 257 RPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFM 316
R V + S++ G + AL+ + LR G LAG +L LY R+ELC P R
Sbjct: 159 RAVFVASLVLTTGLGASEALAASFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLA 218
Query: 317 ITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYW---SIFPESLRWLMAT 373
+M A ++ G L+PGLAAL +DW++LQ L L+LL+W ++FPES WL+AT
Sbjct: 219 FSMGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLAT 278
Query: 374 QQFESAKRLILHFTQKNRMNP-----EGDIKGVIPELEKELSR--RPKKVCIVKVVGTRN 426
Q A++++ F + + + P E + EL +R +P+ + ++ TR
Sbjct: 279 GQVARARKILWRFAEASGVGPGDSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRV 338
Query: 427 LWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVV 486
W+N ++L +SL G GI F RS+ P + FY Y+ A + + + + +
Sbjct: 339 TWRNGLILGFSSLVGGGIRASFRRSL------APQVPTFYLPYFLEAGLEAAALVFLLLT 392
Query: 487 VRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMF 546
GRR LLL ++T LASLL L + ++ + S++G+
Sbjct: 393 ADCCGRRPVLLLGTMVTGLASLLLLAGAQYLPGWT---------------VLFLSVLGLL 437
Query: 547 ASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFAC 606
AS AV +LS F AE+ PTVIR GLGLVL + G + LH ++G+FL ++FA
Sbjct: 438 ASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGLLDTLHGRQGFFLQQVVFAS 497
Query: 607 CTLICIICILLLPESRDQNLPENISNGEHYTRQPLL 642
++ ++C+LLLPESR + LP+++ + + R PLL
Sbjct: 498 LAVLALLCVLLLPESRSRGLPQSLQDADRLRRSPLL 533
>gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo
sapiens]
Length = 495
Score = 153 bits (386), Expect = 6e-37
Identities = 143/486 (29%), Positives = 217/486 (44%), Gaps = 57/486 (11%)
Query: 78 LDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTEL 137
++ + VL GG G ++ L +W+P + +G S+ L QP CR T L
Sbjct: 1 MEQEARVLRAAGGFGRA-RRLLASASWVPCIVLGLVLSSEELLTAQPAPHCRP--DPTLL 57
Query: 138 AGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASN 197
RG + + ++P AP EA G S S A PL P AS
Sbjct: 58 PPALRALRGPALLD-AAIPRLGPTRAPAEALGVLSPSYLA------PLTRAPRPSSWAS- 109
Query: 198 CDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRR 257
C G AG W+LVC + WKV + + S L+G + G +I G D GRR
Sbjct: 110 CS------GAAAG------PTWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRR 157
Query: 258 PVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMI 317
V + S++ G + AL+ + LR G LAG +L LY R+ELC P R
Sbjct: 158 AVFVASLVLTTGLGASEALAASFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAF 217
Query: 318 TMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYW---SIFPESLRWLMATQ 374
+M A ++ G L+PGLAAL +DW++LQ L L+LL+W ++FPES WL+AT
Sbjct: 218 SMGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATG 277
Query: 375 QFESAKRLILHFTQKNRMNP-----EGDIKGVIPELEKELSR--RPKKVCIVKVVGTRNL 427
Q A++++ F + + + P E + EL +R +P+ + ++ TR
Sbjct: 278 QVARARKILWRFAEASGVGPGDSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVT 337
Query: 428 WKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVV 487
W+N ++L +SL G GI ++ G V + A +A +L + V+
Sbjct: 338 WRNGLILGFSSLVGGGIR----ANLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVI 393
Query: 488 R-----------FLGRRGGLL--------LFMILTALASLLQLGLLNLIGKYSQHPDSGM 528
R FLG+ GLL F+ ASL L LL ++ + G+
Sbjct: 394 RGAGLGLVLGAGFLGQAAGLLDTLHGRQGFFLQQVVFASLAVLALLCVL-LLPESRSRGL 452
Query: 529 SDSVKD 534
S++D
Sbjct: 453 PQSLQD 458
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/134 (37%), Positives = 79/134 (58%), Gaps = 7/134 (5%)
Query: 509 LQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIR 568
L LG +L+G G+ ++ + S++G+ AS AV +LS F AE+ PTVIR
Sbjct: 342 LILGFSSLVG-------GGIRANLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIR 394
Query: 569 CGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPE 628
GLGLVL + G + LH ++G+FL ++FA ++ ++C+LLLPESR + LP+
Sbjct: 395 GAGLGLVLGAGFLGQAAGLLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQ 454
Query: 629 NISNGEHYTRQPLL 642
++ + + R PLL
Sbjct: 455 SLQDADRLRRSPLL 468
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 135 bits (341), Expect = 1e-31
Identities = 118/474 (24%), Positives = 212/474 (44%), Gaps = 38/474 (8%)
Query: 183 PPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIF 242
PP S P+ A W Y ++V++WDLVC++ +A+ + G++
Sbjct: 79 PPNASLPNDTQRAMEPCLDGWVYN---STKDSIVTEWDLVCNSNKLKEMAQSIFMAGILI 135
Query: 243 GYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLY 302
G L+ G ++D GRRP+L S + + G A S ++ RF GF ++GI L+
Sbjct: 136 GGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTV 195
Query: 303 ALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLL--YW 360
L +E P R +++ + GQF++PGLA W+ LQ + PF + L +W
Sbjct: 196 ILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWW 255
Query: 361 SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD---IKGVIPELEKELSRRPKKVC 417
+ PES+RWL+ + + A +++ N EG+ ++ + L+KE+S K
Sbjct: 256 T--PESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYT 313
Query: 418 IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHE---VKVPLLENFYADYYTTAS 474
+ L + + C+ SL + + MG E V + +L+ + A
Sbjct: 314 ASDLFRIPMLRR--MTFCL-SLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAK 370
Query: 475 IALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKD 534
+ L+ +LGR ++L A L L + Q + ++ K
Sbjct: 371 FITILSLS------YLGRHTTQAAALLLAGGAIL----ALTFVPLDLQTVRTVLAVFGKG 420
Query: 535 KFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQ 594
S +FS + ++ S E+ PTVIR G+G+ G + +P++++ +
Sbjct: 421 CLSSSFSCLFLYTS------------ELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGE 468
Query: 595 KGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGE 648
F+ +II+ L+ L LPE+ +Q LPE I + E+++ + P ++ E
Sbjct: 469 VQPFIPNIIYGITALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPE 522
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 132 bits (333), Expect = 8e-31
Identities = 138/556 (24%), Positives = 238/556 (42%), Gaps = 51/556 (9%)
Query: 93 GGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPN-FWCRG--AGKGTELAGVTTTGRGGDM 149
G +Q+ + LL + + F FL QP+ +WCRG A E G +
Sbjct: 15 GRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAERCGWSPEEEWNRT 74
Query: 150 GNWTSLPTTPFATAPWEA----AGNRSNSSGADGGDTPPLPSPPDKGDNASNCDCRA-WD 204
+ P P + A N S S+ + PL + P++ +A CR W
Sbjct: 75 APASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNR--SAPLVPCRGGWR 132
Query: 205 YGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSI 264
Y A +VS++DLVC NAW + + + L +G + G G AD GR + L S
Sbjct: 133 Y---AQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSC 189
Query: 265 IFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFV 324
+ + + G+ VA + N +F RF +G G +T Y + E+ +R ++ +V
Sbjct: 190 LGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMF 249
Query: 325 AMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLIL 384
G ++PG+A +WQ +Q I P L LLY+ + PES RWL+ ++ + A +++
Sbjct: 250 FTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILR 309
Query: 385 HFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGI 444
+ N + I ++E+S + +V T + K ++L T +
Sbjct: 310 RIAKCNGKYLSSNY-SEITVTDEEVS----NPSFLDLVRTPQMRKCTLILMFAWFTSAVV 364
Query: 445 HHCFARSMMGHEVKVPLL-ENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILT 503
+ G +++ ++ N Y D++ + + L L + + + LGRR L
Sbjct: 365 Y-------QGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRR--------LP 409
Query: 504 ALASLLQLGLLNLIGKYSQHPDSGMSDSV----KDKFSIAFSIVGMFASHAVGSLSVFFC 559
AS + G+ L+ + + + +V + ++AF IV + S
Sbjct: 410 FAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNS----------- 458
Query: 560 AEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYF-LHHIIFACCTLICIICILLL 618
E+ PT +R G+ L FG + AP + + L IIF IC ++LL
Sbjct: 459 -ELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLL 517
Query: 619 PESRDQNLPENISNGE 634
PE++ LPE + + E
Sbjct: 518 PETKGIALPETVDDVE 533
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 132 bits (331), Expect = 1e-30
Identities = 108/488 (22%), Positives = 212/488 (43%), Gaps = 32/488 (6%)
Query: 183 PPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIF 242
P L G A+ W Y + +V++WDLVC + +A+ +VG++
Sbjct: 89 PFLNGTEANGTGATEPCTDGWIYD-NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 243 GYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLY 302
G ++ G +AD +GRR VL+ + + + G A + N ++ R G LAGI L
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 303 ALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSI 362
L +E P R + + +V GQFL+ G+A W+ LQ L+ PF +Y
Sbjct: 208 TLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWF 267
Query: 363 FPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DIKGVIPELEKELSRRPKKVCIV 419
F ES RW ++ + + R + + N EG ++ + L+KEL+ + +
Sbjct: 268 FIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAM 327
Query: 420 KVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIA 476
+++ L + LC++ L T + ++ + G V + L++ + ++
Sbjct: 328 ELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGFGVSIYLIQVIF------GAVD 378
Query: 477 LVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKF 536
L + L +V+ LGRR + ++L + LL +G+ +
Sbjct: 379 LPAKLVGFLVINSLGRRPAQMAALLLAGICILL----------------NGVIPQDQSIV 422
Query: 537 SIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKG 596
+ +++G A + + E+ PT+IR G+G+ A G + +P++ + +
Sbjct: 423 RTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELY 482
Query: 597 YFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQPLLLTNA 656
+ I+ + +LLPE+ Q LP+ + + E + ++ ++ ++ A
Sbjct: 483 PSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVPLQA 542
Query: 657 ELKDYSGL 664
++ +GL
Sbjct: 543 SAQEKNGL 550
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 130 bits (327), Expect = 4e-30
Identities = 105/458 (22%), Positives = 199/458 (43%), Gaps = 32/458 (6%)
Query: 183 PPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIF 242
P L G A+ W Y + +V++WDLVC + +A+ +VG++
Sbjct: 89 PFLNGTEANGTGATEPCTDGWIYD-NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 243 GYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLY 302
G ++ G +AD +GRR VL+ + + + G A + N ++ R G LAGI L
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 303 ALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSI 362
L +E P R + + +V GQFL+ G+A W+ LQ L+ PF +Y
Sbjct: 208 TLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWF 267
Query: 363 FPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DIKGVIPELEKELSRRPKKVCIV 419
F ES RW ++ + + R + + N EG ++ + L+KEL+ + +
Sbjct: 268 FIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAM 327
Query: 420 KVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIA 476
+++ L + LC++ L T + ++ + G V + L++ + ++
Sbjct: 328 ELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGFGVSIYLIQVIF------GAVD 378
Query: 477 LVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKF 536
L + L +V+ LGRR + ++L + LL +G+ +
Sbjct: 379 LPAKLVGFLVINSLGRRPAQMAALLLAGICILL----------------NGVIPQDQSIV 422
Query: 537 SIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKG 596
+ +++G A + + E+ PT+IR G+G+ A G + +P++ + +
Sbjct: 423 RTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELY 482
Query: 597 YFLHHIIFACCTLICIICILLLPESRDQNLPENISNGE 634
+ I+ + +LLPE+ Q LP+ + + E
Sbjct: 483 PSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 130 bits (327), Expect = 4e-30
Identities = 113/429 (26%), Positives = 197/429 (45%), Gaps = 35/429 (8%)
Query: 215 VVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTV 274
+V+KWDLVCD + +F LL G++ G +I G ++D GRR +L + ++ + I
Sbjct: 131 IVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCLLQLAITDTCA 190
Query: 275 ALSVNVTMFSTLRFFEGFCLAGIILTLYALRI-ELCPPGKRFMITMVASFVAMAGQFLMP 333
A + ++ LRF GF + II++ +L I E P + ++ +++S GQ ++
Sbjct: 191 AFAPTFPVYCVLRFLAGFS-SMIIISNNSLPITEWIRPNSKALVVILSSGALSIGQIILG 249
Query: 334 GLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRM- 392
GLA + RDWQ L + PF + L ES RWL+ T + + + + + N +
Sbjct: 250 GLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNGIK 309
Query: 393 NPEG--DIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLC----VNSLTGYGIHH 446
N E +I+ V +++EL K + + ++ K I +L N++ YG
Sbjct: 310 NAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRFANTIPFYGT-- 367
Query: 447 CFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALA 506
++ + LL+ Y A +V CLA+ + + +GRR +LFM L L+
Sbjct: 368 --MVNLQHVGSNIFLLQVLYG-----AVALIVRCLAL-LTLNHMGRRISQILFMFLVGLS 419
Query: 507 SLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTV 566
L + K Q +A + +G+ S A S E+ PTV
Sbjct: 420 ILAN----TFVPKEMQ------------TLRVALACLGIGCSAATFSSVAVHFIELIPTV 463
Query: 567 IRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNL 626
+R G+ L ++ G AP++ L II+ +I + + LLPE+++ L
Sbjct: 464 LRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWIIYGIFPIIGGLIVFLLPETKNLPL 523
Query: 627 PENISNGEH 635
P+ I + E+
Sbjct: 524 PDTIKDVEN 532
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 127 bits (318), Expect = 4e-29
Identities = 132/563 (23%), Positives = 228/563 (40%), Gaps = 48/563 (8%)
Query: 84 VLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGVTTT 143
+L LG +G +Q L +P + F +F P CRG TE +
Sbjct: 6 LLDALGSMGR-FQLNHTALLLLPCGLLACHNFLQNFTAAVPPHHCRGPANHTEAST---- 60
Query: 144 GRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPP---LPSPPDKGDNASNCDC 200
D G W AT P + G T P L SP A+ C
Sbjct: 61 ---NDSGAWLR------ATIPLDQLGAPEPCRRF----TKPQWALLSPNSSIPGAATEGC 107
Query: 201 R-AWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPV 259
+ W Y R+ +V +WDLVC+ +A+ + G++ G + G +AD +G +
Sbjct: 108 KDGWVYN-RSVFPSTIVMEWDLVCEARTLRDLAQSVYMAGVLVGAAVFGSLADRLGCKGP 166
Query: 260 LLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITM 319
L++S + + G A + + + RF G +GIIL +L +E P R + +
Sbjct: 167 LVWSYLQLAASGAATAYFSSFSAYCVFRFLMGMTFSGIILNSVSLVVEWMPTRGRTVAGI 226
Query: 320 VASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESA 379
+ + GQ ++ G+A L R W+ LQ I PFL+ LY PES RWL+ + + A
Sbjct: 227 LLGYSFTLGQLILAGVAYLIRPWRCLQFAISAPFLIFFLYSWWLPESSRWLLLHGKSQLA 286
Query: 380 KRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSL 439
+ + N EG+ L KE+ + V + ++ + +
Sbjct: 287 VQNLQKVAAMNGRKEEGE------RLTKEVMSSYIQSEFASVCTSNSILDLFRTPAIRKV 340
Query: 440 TGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVR---FLGRRGGL 496
T + F+ S+ + + + L + + Y A +++ AM V ++GRR +
Sbjct: 341 TCCLMVIWFSNSVAYYGLAMDLQKFGLSLYLVQALFGIINTPAMLVATATMIYVGRRATV 400
Query: 497 LLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSV 556
F+IL L + + + + +Q + + K + +F V +F
Sbjct: 401 ASFLILAGLMVIANM----FVPEGTQILCTAQAALGKGCLASSFICVYLFT--------- 447
Query: 557 FFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICIL 616
E+ PT IR G+G A G LTAP++ + L + F ++ + +
Sbjct: 448 ---GELYPTEIRQMGMGFASVHARLGGLTAPLVTTLGEYSTILPPVSFGATAILAGLAVC 504
Query: 617 LLPESRDQNLPENISNGEHYTRQ 639
+L E+R+ L E I+ E ++
Sbjct: 505 VLTETRNMPLVETIAAMERRVKE 527
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 124 bits (310), Expect = 4e-28
Identities = 119/453 (26%), Positives = 193/453 (42%), Gaps = 43/453 (9%)
Query: 193 DNASNCDC-RAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIA 251
D + C + W+Y + + ++WDLVC+ A G++ G + G ++
Sbjct: 106 DEPATVPCSQGWEYD-HSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLS 164
Query: 252 DWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPP 311
D GRR +LL + + L+ GL A SV+ MF+ R G LAG + + L +E
Sbjct: 165 DRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDV 224
Query: 312 GKRFMITMVASFVAMAGQFLMPGLAALCRDWQ--VLQALIICPFLLMLLYWSIFPESLRW 369
R + +++S G L+ + L RDW+ +L + C ++ L+W PES RW
Sbjct: 225 EHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWW--VPESARW 282
Query: 370 LMATQQFESAKRLILHFTQKN-------RMNPEGDIKGVIPELEKELSRRPKKVCIVKVV 422
L+ + A R +LH + N + E K E + RRP + + +
Sbjct: 283 LLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGE---RVVRRPSYLDLFRTP 339
Query: 423 GTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLE-NFYADYYTTASIALVSCL 481
R +I + CV + +G++ S G + V L N Y ++ L S L
Sbjct: 340 RLR----HISLCCV--VVWFGVNF----SYYGLSLDVSGLGLNVYQTQLLFGAVELPSKL 389
Query: 482 AMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFS 541
+ + VR+ GRR L T L + L G L+ S +S +
Sbjct: 390 LVYLSVRYAGRR----LTQAGTLLGTALAFGTRLLV------------SSDMKSWSTVLA 433
Query: 542 IVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHH 601
++G S A + + F +E+ PTV+R G+GL G AP+ L + L
Sbjct: 434 VMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPK 493
Query: 602 IIFACCTLICIICILLLPESRDQNLPENISNGE 634
+ + L+ LLLPE+R LPE I + E
Sbjct: 494 LTYGGIALLAAGTALLLPETRQAQLPETIQDVE 526
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 121 bits (304), Expect = 2e-27
Identities = 116/428 (27%), Positives = 184/428 (42%), Gaps = 41/428 (9%)
Query: 217 SKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVAL 276
S+WDLVC+ A G++ G + G ++D GRR +LL + + L+ GL A
Sbjct: 132 SQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAA 191
Query: 277 SVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLA 336
SV+ MF+ R G LAG + + L +E R + +++S G L+ +
Sbjct: 192 SVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVG 251
Query: 337 ALCRDWQ--VLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKN---- 390
L RDW+ +L + C ++ L+W PES RWL+ + A R +LH + N
Sbjct: 252 YLIRDWRWLLLAVTLPCAPGILSLWW--VPESARWLLTQGHVKEAHRYLLHCARLNGRPV 309
Query: 391 ---RMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHC 447
+ E K E + RRP + + + R +I + CV + +G++
Sbjct: 310 CEDSFSQEAVSKVAAGE---RVVRRPSYLDLFRTPRLR----HISLCCV--VVWFGVNF- 359
Query: 448 FARSMMGHEVKVPLLE-NFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALA 506
S G + V L N Y ++ L S L + + VR+ GRR L T L
Sbjct: 360 ---SYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRR----LTQAGTLLG 412
Query: 507 SLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTV 566
+ L G L+ S +S +++G S A + + F +E+ PTV
Sbjct: 413 TALAFGTRLLV------------SSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTV 460
Query: 567 IRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNL 626
+R G+GL G AP+ L + L + + L+ LLLPE+R L
Sbjct: 461 LRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQL 520
Query: 627 PENISNGE 634
PE I + E
Sbjct: 521 PETIQDVE 528
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 120 bits (300), Expect = 5e-27
Identities = 137/568 (24%), Positives = 231/568 (40%), Gaps = 67/568 (11%)
Query: 79 DYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELA 138
DYD V+ FLG G +Q+ + L + GF+ S FL P CR + A
Sbjct: 3 DYD-EVIAFLGEWGP-FQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVP----DAA 56
Query: 139 GVTTTGRGGDMG-NWTSLPTTPFATAPWEAA--GNRSNSSGADGGDTPPLPSPPDKGDNA 195
+++ R + P + + + A N S G D D G
Sbjct: 57 NLSSAWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDV-------DLGQLE 109
Query: 196 SNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVG 255
W++ L VV++W+LVC++ WKV + VG++ G ++G ++D G
Sbjct: 110 QESCLDGWEFSQDVYL-STVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFG 168
Query: 256 RRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRF 315
R+ VL ++ F S++ MF+ L G + + L E+ R
Sbjct: 169 RKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRI 228
Query: 316 MITM--VASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMAT 373
+ + V +F A+ G L+P A RDW++L + P +L + W PES RWL++
Sbjct: 229 IFSTLGVCTFFAV-GYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQ 287
Query: 374 QQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNL-WKNIV 432
++F A+ +I + N + I + EL + +K I+ + TRN+ I+
Sbjct: 288 RRFREAEDIIQKAAKMNNIAVPAVIFDSVEELN---PLKQQKAFILDLFRTRNIAIMTIM 344
Query: 433 VLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGR 492
L + LT G FA S+ L + Y + + +A I + + + +++R L R
Sbjct: 345 SLLLWMLTSVGY---FALSLDAPN----LHGDAYLNCFLSALIEIPAYITAWLLLRTLPR 397
Query: 493 R----------GGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSI 542
R GG+LLF+ L + SI +
Sbjct: 398 RYIIAAVLFWGGGVLLFIQLVPVDYYF--------------------------LSIGLVM 431
Query: 543 VGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHI 602
+G F + S+ F AE+ PT++R +G+ ++ G + AP L +I
Sbjct: 432 LGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYI 491
Query: 603 IFACCTLICIICILLLPESRDQNLPENI 630
+ T++ I L PES LPE +
Sbjct: 492 VMGSLTVLIGILTLFFPESLGMTLPETL 519
>gi|42542386 solute carrier family 22 (organic anion/cation
transporter), member 9 [Homo sapiens]
Length = 553
Score = 119 bits (299), Expect = 7e-27
Identities = 114/479 (23%), Positives = 201/479 (41%), Gaps = 61/479 (12%)
Query: 194 NASNCDCR----AWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGC 249
N S+ D W Y R +V++WDLVCD+ +AKF + G++ G ++ G
Sbjct: 107 NTSDADMEPCVDGWVYD-RISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGH 165
Query: 250 IADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIE-- 307
++D GRR VL + + + I G AL+ ++ +LRF G +I L E
Sbjct: 166 LSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWA 225
Query: 308 ------------LCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLL 355
+CP G FM + GLA RDW +LQ ++ P+ +
Sbjct: 226 THRFQAMGITLGMCPSGIAFMT--------------LAGLAFAIRDWHILQLVVSVPYFV 271
Query: 356 MLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD---IKGVIPELEKEL-SR 411
+ L S ES RWL+ + E + + ++ M D ++ + ++KEL +
Sbjct: 272 IFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAA 331
Query: 412 RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYT 471
+ KK + +++ N+ K I +L + + + V LL+ +
Sbjct: 332 QKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFG---- 387
Query: 472 TASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDS 531
A I L +C+A + +++ RR +L M L A+ L + + + +
Sbjct: 388 -AVILLANCVAPWAL-KYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLRE--------- 436
Query: 532 VKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIEL 591
+ +G+ AS +L+ E+ PT+IR +G+ A AP++ +
Sbjct: 437 -------VLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMI 489
Query: 592 HNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQP 650
+ L II+ I LLLPE+R++ L + I + ++ + P P K E P
Sbjct: 490 LSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNERKDPREP--KQEDP 546
>gi|157426885 organic cation transporter like 4 [Homo sapiens]
Length = 594
Score = 115 bits (288), Expect = 1e-25
Identities = 145/559 (25%), Positives = 238/559 (42%), Gaps = 67/559 (11%)
Query: 93 GGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGA---GKGTELAGVTTTGRGGDM 149
G +Q+ LV LT+IP++ F F+D F+ +C + G L+
Sbjct: 63 GTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLSKAEQLNLTIPQ 122
Query: 150 G-NWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASNCDCRAWDYGIR 208
N + L + PW L S G N ++ W Y
Sbjct: 123 APNGSFLTCFMYLPVPWN------------------LDSIIQFGLNDTDTCQDGWIYP-- 162
Query: 209 AGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFIL 268
+++++++DLVC K A+ + GL G LI I D +GR P +L S++ ++
Sbjct: 163 DAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLI 222
Query: 269 IFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAG 328
IFG A + ++ RF + G ++ +L E R ++ G
Sbjct: 223 IFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHCFFAVG 282
Query: 329 QFLMPGLAALCRDWQVL---QALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILH 385
L+ G+A WQ+L +++ PF + Y I PES RWLM + + AK+++ +
Sbjct: 283 AVLLTGIAYSLPHWQLLFLVGGILVIPF---ISYIWILPESPRWLMMKGKVKEAKQVLCY 339
Query: 386 FTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVG---TRNLWK-NIVVLCVNSLTG 441
N+ K + L EL KKV V+ R L K +V+ CV
Sbjct: 340 AASVNK-------KTIPSNLLDELQLPRKKVTRASVLDFCKNRQLCKVTLVMSCVWFTVS 392
Query: 442 YGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCV-VVRFLGRRGGLLLFM 500
Y F S+ E+ V + +F + SI V C+ +++ +GR+ L + +
Sbjct: 393 YTY---FTLSLRMRELGVSV--HF---RHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTL 444
Query: 501 ILTALASLLQL----GLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSV 556
+ + LL L G L K+ + P + + +I ++ F+ A ++
Sbjct: 445 LQAIIWCLLLLFLPEGEDGLRLKWPRCPATELK-----SMTILVLMLREFSLAATVTVFF 499
Query: 557 FFCAEITPTVIRCGGLGLV-LASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICI 615
+ AE+ PTV+R GLGLV LAS +L+ II +Q L IF CC L +
Sbjct: 500 LYTAELLPTVLRATGLGLVSLASVAGAILSLTII---SQTPSLLP--IFLCCVLAIVAFS 554
Query: 616 L--LLPESRDQNLPENISN 632
L LLPE+RDQ L E++++
Sbjct: 555 LSSLLPETRDQPLSESLNH 573
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 115 bits (287), Expect = 2e-25
Identities = 102/427 (23%), Positives = 180/427 (42%), Gaps = 26/427 (6%)
Query: 214 NVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLT 273
++V++++LVC ++WK+ + + L G +FG L G AD GR+ LL +++ + G+
Sbjct: 133 SIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVL 192
Query: 274 VALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMP 333
+A S N R +G G + Y L E G R + ++ G +
Sbjct: 193 MAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALT 252
Query: 334 GLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMN 393
GLA W+ LQ + P L LLY+ PES RWL++ ++ A +++ H QKN
Sbjct: 253 GLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKL 312
Query: 394 PEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMM 453
P D+K + LE++++ + + T L K +L T ++ M
Sbjct: 313 PPADLK--MLSLEEDVTEK-LSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMG 369
Query: 454 GHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGL 513
N Y D+ +A + + + + +GR + + +L A L+ + +
Sbjct: 370 ATS------GNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFI 423
Query: 514 LNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLG 573
PD +I VG + AE+ PT +R G+
Sbjct: 424 ---------SPDLHW-------LNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVM 467
Query: 574 LVLASAGFGMLTAPIIELHNQKGY-FLHHIIFACCTLICIICILLLPESRDQNLPENISN 632
+ + G + P I ++ + L I+FA L+ LLLPE++ LPE + +
Sbjct: 468 VCSSLCDIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKD 527
Query: 633 GEHYTRQ 639
E+ R+
Sbjct: 528 AENLGRK 534
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 113 bits (283), Expect = 5e-25
Identities = 132/557 (23%), Positives = 232/557 (41%), Gaps = 43/557 (7%)
Query: 79 DYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELA 138
DYD V FLG G +Q+ + L + GF+ S FL+ P CR + A
Sbjct: 3 DYD-EVTAFLGEWGP-FQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVP----DAA 56
Query: 139 GVTTTGRGGDMG-NWTSLPTTPFATAPWEAA--GNRSNSSGADGGDTPPLPSPPDKGDNA 195
+++ R + P + + A N S G D D G
Sbjct: 57 NLSSAWRNHTVPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDV-------DLGQLE 109
Query: 196 SNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVG 255
W++ L +V++W+LVC++ WK + VG++ G I+G ++D G
Sbjct: 110 QESCLDGWEFSQDVYL-STIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFG 168
Query: 256 RRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRF 315
R+ VL ++ F S N MF L G + + L E+ R
Sbjct: 169 RKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRI 228
Query: 316 MITMVASFVAMA-GQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQ 374
+ + + + A G ++P A RDW++L + P +L + W PES RWL++
Sbjct: 229 IFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQG 288
Query: 375 QFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVL 434
+FE A+ +I + N + I EL+ S++ + I+ ++ T W NI ++
Sbjct: 289 RFEEAEVIIRKAAKANGIVVPSTIFDP-SELQDLSSKKQQSHNILDLLRT---W-NIRMV 343
Query: 435 CVNSLTGYGIHHCFARSMMGHEVKVPLLE-NFYADYYTTASIALVSCLAMCVVVRFLGRR 493
+ S+ + + G + P L + + + + +A + + + + +++++L RR
Sbjct: 344 TIMSIM---LWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRR 400
Query: 494 GGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGS 553
++A+ L LG L+ PD +V +VG F A S
Sbjct: 401 ---------YSMATALFLGGSVLLFMQLVPPDLYYLATV-------LVMVGKFGVTAAFS 444
Query: 554 LSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICII 613
+ + AE+ PTV+R G+G+ ++ G + +P FL +I+ T++ I
Sbjct: 445 MVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI 504
Query: 614 CILLLPESRDQNLPENI 630
L LPES LP+ I
Sbjct: 505 LTLFLPESFGTPLPDTI 521
>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
Length = 553
Score = 112 bits (279), Expect = 1e-24
Identities = 103/440 (23%), Positives = 191/440 (43%), Gaps = 40/440 (9%)
Query: 203 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 262
W Y R+ +V+KW+LVCD+ +A+ L G++ G G +D GRR VL +
Sbjct: 120 WVYD-RSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTW 178
Query: 263 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVAS 322
S + + + G A + ++ RF F +AG+++ L +E R ++ + S
Sbjct: 179 SYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNS 238
Query: 323 FVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRL 382
G L +A RDW +LQ ++ PF L LY ES RWL+ T + +
Sbjct: 239 LGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWG--- 295
Query: 383 ILHFTQKNRMNPEGDIKGVI-PEL-------EKELSRRPKKV-CIVKVVGTRNLWKNIVV 433
+ + +N +G ++ + PE+ E + + P + ++++ G R
Sbjct: 296 LQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLR------FR 349
Query: 434 LCVNSLTGYGIHHCFARSMMGHEVKVPLL-ENFYADYYTTASIALVSCLAMCVVVRFLGR 492
C+++L + F + G + + L N + + + + + +++ LGR
Sbjct: 350 TCISTLCWF----AFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGR 405
Query: 493 RGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVG 552
R T ASLL GL L H + A +++G+ A
Sbjct: 406 RP--------TLAASLLLAGLCILANTLVPHEMGALRS--------ALAVLGLGGVGAAF 449
Query: 553 SLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICI 612
+ + +E+ PTV+R +GL +A G + P++ L G +L +++ ++
Sbjct: 450 TCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSG 509
Query: 613 ICILLLPESRDQNLPENISN 632
+ LLLPE++ LP+ I +
Sbjct: 510 LAALLLPETQSLPLPDTIQD 529
>gi|166064021 solute carrier family 22 (organic anion transporter),
member 13 [Homo sapiens]
Length = 551
Score = 112 bits (279), Expect = 1e-24
Identities = 110/465 (23%), Positives = 201/465 (43%), Gaps = 59/465 (12%)
Query: 198 CDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRR 257
CD W+Y + ++ ++++LVCD + + GL+ G L+ G + D +GR+
Sbjct: 109 CDM-GWEYP--ENRLPSLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRK 165
Query: 258 PVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMI 317
+L ++ + GL A + ++ LRF +AG+ + L E P R
Sbjct: 166 ATILAQLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQA 225
Query: 318 TMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFE 377
++A GQ ++ GLA R+W++LQ P LL+ Y+ PES RWL+ + +
Sbjct: 226 VVLAQCNFSLGQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMD 285
Query: 378 SAKRLILHFTQKNR--MNPEGDIKGVIPEL------EKELSRRPKKVCIVKVVGTRNLWK 429
A +LI NR ++PE + ++PE +L R P+ + ++
Sbjct: 286 EAIQLIQKAASVNRRKLSPE-LMNQLVPEKTGPSGNALDLFRHPQLRKVTLII------- 337
Query: 430 NIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASI-----ALVSCLAMC 484
V V+SL YG+ S+ + +F D Y T I C ++
Sbjct: 338 -FCVWFVDSLGYYGL------SLQ--------VGDFGLDVYLTQLIFGAVEVPARCSSIF 382
Query: 485 VVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVG 544
++ RF GR+ L ++L L ++ + + + ++VG
Sbjct: 383 MMQRF-GRKWSQLGTLVLGGLMCIIIIFI----------------PADLPVVVTMLAVVG 425
Query: 545 MFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIF 604
A+ A ++S + AE+ PT++R G+GLV + G + P++ L + L +I+
Sbjct: 426 KMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIY 485
Query: 605 ACCTLICIICILLLPESRDQNLPENISN---GEHYTRQPLLPHKK 646
++ + LLPE+ Q L + + + G H +P +K
Sbjct: 486 GSLPIVAGLLCTLLPETHGQGLKDTLQDLELGPHPRSPKSVPSEK 530
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 110 bits (275), Expect = 4e-24
Identities = 83/333 (24%), Positives = 150/333 (45%), Gaps = 16/333 (4%)
Query: 183 PPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIF 242
P L G A+ W Y + +V++WDLVC + +A+ +VG++
Sbjct: 89 PFLNGTEANGTGATEPCTDGWIYD-NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 243 GYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLY 302
G ++ G +AD +GRR VL+ + + + G A + N ++ R G LAGI L
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 303 ALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSI 362
L +E P R + + +V GQFL+ G+A W+ LQ L+ PF +Y
Sbjct: 208 TLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWF 267
Query: 363 FPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DIKGVIPELEKELSRRPKKVCIV 419
F ES RW ++ + + R + + N EG ++ + L+KEL+ + +
Sbjct: 268 FIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAM 327
Query: 420 KVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIA 476
+++ L + LC++ L T + ++ + G V + L++ + ++
Sbjct: 328 ELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGFGVSIYLIQVIF------GAVD 378
Query: 477 LVSCLAMCVVVRFLGRRGGLLLFMILTALASLL 509
L + L +V+ LGRR + ++L + LL
Sbjct: 379 LPAKLVGFLVINSLGRRPAQMAALLLAGICILL 411
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 110 bits (275), Expect = 4e-24
Identities = 83/333 (24%), Positives = 150/333 (45%), Gaps = 16/333 (4%)
Query: 183 PPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIF 242
P L G A+ W Y + +V++WDLVC + +A+ +VG++
Sbjct: 89 PFLNGTEANGTGATEPCTDGWIYD-NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 243 GYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLY 302
G ++ G +AD +GRR VL+ + + + G A + N ++ R G LAGI L
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 303 ALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSI 362
L +E P R + + +V GQFL+ G+A W+ LQ L+ PF +Y
Sbjct: 208 TLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWF 267
Query: 363 FPESLRWLMATQQFESAKRLILHFTQKNRMNPEG---DIKGVIPELEKELSRRPKKVCIV 419
F ES RW ++ + + R + + N EG ++ + L+KEL+ + +
Sbjct: 268 FIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAM 327
Query: 420 KVVGTRNLWKNIVVLCVNSL---TGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIA 476
+++ L + LC++ L T + ++ + G V + L++ + ++
Sbjct: 328 ELLRCPTL--RHLFLCLSMLWFATSFA-YYGLVMDLQGFGVSIYLIQVIF------GAVD 378
Query: 477 LVSCLAMCVVVRFLGRRGGLLLFMILTALASLL 509
L + L +V+ LGRR + ++L + LL
Sbjct: 379 LPAKLVGFLVINSLGRRPAQMAALLLAGICILL 411
>gi|211059435 solute carrier family 22, member 24 [Homo sapiens]
Length = 551
Score = 108 bits (271), Expect = 1e-23
Identities = 103/440 (23%), Positives = 173/440 (39%), Gaps = 34/440 (7%)
Query: 203 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 262
W Y R+ + +V++WDLVC++ + + + G + G LI G ++D VGR+ +
Sbjct: 120 WVYD-RSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKL 178
Query: 263 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVAS 322
+ + I A + ++ LRF GF I+ + L +E P R M MV
Sbjct: 179 CFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLL 238
Query: 323 FVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAK-- 380
GQ L+ GLA +DW +LQ + P +++ L ES RWL+ Q +
Sbjct: 239 CSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKE 298
Query: 381 -RLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSL 439
R + H K + V ++KEL K I + L + LC
Sbjct: 299 LRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLC---- 354
Query: 440 TGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLF 499
F R + VP + ++++L L C V F R LL
Sbjct: 355 --------FVR----FAITVPFYGLILNLQHLGSNVSLFQIL--CGAVTFTARCVSLLTL 400
Query: 500 ----MILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLS 555
++ + +GL L+ + + + +G+ + A + +
Sbjct: 401 NHMGRRISQILFTFPVGLFILVNTFLPQE--------MQILRVVLATLGIGSVSAASNSA 452
Query: 556 VFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICI 615
E+ PT++R G+ S G AP++ L I + ++ + I
Sbjct: 453 SVHHNELVPTILRSTVAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILAVPVI 512
Query: 616 LLLPESRDQNLPENISNGEH 635
LLLPE+RD LP I + E+
Sbjct: 513 LLLPETRDLPLPNTIQDVEN 532
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 108 bits (269), Expect = 2e-23
Identities = 106/446 (23%), Positives = 189/446 (42%), Gaps = 40/446 (8%)
Query: 214 NVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLT 273
++V++++LVC N+W + + + S+ VG G + G IAD GR+ LL +++ G+
Sbjct: 134 SIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVL 193
Query: 274 VALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMA---GQF 330
+A+S T R +G L Y L E G+R+ T V F +A G
Sbjct: 194 MAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFV--GRRYRRT-VGIFYQVAYTVGLL 250
Query: 331 LMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKN 390
++ G+A W+ LQ + P LLY+ PES RWL++ + A R+I H +KN
Sbjct: 251 VLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKN 310
Query: 391 RMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFAR 450
+ ++ + LE+E ++ + +V T + K+ ++L N T ++
Sbjct: 311 GKSLPASLQRL--RLEEETGKKLNP-SFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIM 367
Query: 451 SM--MGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASL 508
M G +N Y D++ +A + + + + + +GRR ++ A L
Sbjct: 368 HMGLAG--------DNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACL 419
Query: 509 LQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIR 568
+ + + I S +G + AE+ PT IR
Sbjct: 420 ASVFIPGDL----------------QWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIR 463
Query: 569 CGGLGLVLASAGFGMLTAPIIELHNQKGYF-LHHIIFACCTLICIICILLLPESRDQNLP 627
G+ + + G + P + + L ++F L+ +LLLPE++ + LP
Sbjct: 464 NLGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALP 523
Query: 628 ENISNGEHYTRQPLLPHKKGEQPLLL 653
E I E+ R P K E+ + L
Sbjct: 524 ETIEEAENMQR----PRKNKEKMIYL 545
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 107 bits (267), Expect = 4e-23
Identities = 106/447 (23%), Positives = 194/447 (43%), Gaps = 50/447 (11%)
Query: 203 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 262
W Y R+ +V+KWDLVC + +++ + G++ G I G ++ GR+P+L +
Sbjct: 117 WVYD-RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSW 175
Query: 263 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVAS 322
+ + + G + + ++ LRF F +AGI L+ L +E +R + V
Sbjct: 176 CCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVG 235
Query: 323 FVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLM-------ATQQ 375
AGQ + GLA RDW+ LQ PF + L PES RWL+ A Q+
Sbjct: 236 CAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQE 295
Query: 376 FESAKRLILHFTQKNRMNPEGDIKGVIPELEKEL--SRRPKKVCIVKVVGTRNLWKNIVV 433
R+ H KN I+ ++ +++E+ ++ P+ V + V W++ +
Sbjct: 296 LRKVARINGHKEAKNL-----TIEVLMSSVKEEVASAKEPRSVLDLFCVPVLR-WRSCAM 349
Query: 434 LCVN---SLTGYGIHHCFARSMMGHEVKVPLLENFY--ADYYTTASIALVSCLAMCVVVR 488
L VN ++ YG+ F +G ++ LL+ + D+ A+ AL ++
Sbjct: 350 LVVNFSLLISYYGL--VFDLQSLGRDIF--LLQALFGAVDFLGRATTAL--------LLS 397
Query: 489 FLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFAS 548
FLGRR + LA L + L+ + Q + F+++G
Sbjct: 398 FLGRRTIQAGSQAMAGLAILANM----LVPQDLQ------------TLRVVFAVLGKGCF 441
Query: 549 HAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCT 608
+ + AE+ PT +R G++ G + P+I + Q L +++ +
Sbjct: 442 GISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVIS 501
Query: 609 LI-CIICILLLPESRDQNLPENISNGE 634
+ ++ + LPE++ LP+ I + E
Sbjct: 502 IASSLVVLFFLPETQGLPLPDTIQDLE 528
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 99.0 bits (245), Expect = 1e-20
Identities = 73/298 (24%), Positives = 131/298 (43%), Gaps = 9/298 (3%)
Query: 214 NVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLT 273
++V++++LVC ++WK+ + + L G +FG L G AD GR+ LL +++ + G+
Sbjct: 133 SIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVL 192
Query: 274 VALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMP 333
+A S N R +G G + Y L E G R + ++ G +
Sbjct: 193 MAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALT 252
Query: 334 GLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMN 393
GLA W+ LQ + P L LLY+ PES RWL++ ++ A +++ H QKN
Sbjct: 253 GLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKL 312
Query: 394 PEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMM 453
P D+K + LE++++ + + T L K +L T ++ M
Sbjct: 313 PPADLK--MLSLEEDVTEK-LSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMG 369
Query: 454 GHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQL 511
N Y D+ +A + + + + +GR + + +L A L+ +
Sbjct: 370 ATS------GNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMI 421
>gi|153791484 putative UST1-like organic anion transporter [Homo
sapiens]
Length = 547
Score = 98.6 bits (244), Expect = 2e-20
Identities = 102/445 (22%), Positives = 192/445 (43%), Gaps = 44/445 (9%)
Query: 203 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 262
W Y ++ +V+KWDLVC++ +AKF + G++ G + G ++D GR+ VL +
Sbjct: 120 WVYD-QSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLRW 178
Query: 263 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVAS 322
S + + I G A + + ++ +LRF G II+ L +E M +
Sbjct: 179 SYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLTL 238
Query: 323 FVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRL 382
A G + LA + RD +LQ ++ P + L+ ES RWL+ + E +
Sbjct: 239 CAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKE 298
Query: 383 ILHFTQKNRMNPEGDI---KGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLC---- 435
+ +N M DI + + +++EL KK + +++ N+ K I L
Sbjct: 299 LRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSFVRF 358
Query: 436 VNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCV---VVRFLGR 492
+++ +G+ +G+ V LL+ + V+ LA CV + + R
Sbjct: 359 ASTIPFWGL--TLHLQHLGNNVF--LLQTLF---------GAVTLLANCVAPWALNHMSR 405
Query: 493 RGG--LLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHA 550
R LL+F++ T L +++ + + +G+ A+
Sbjct: 406 RLSQMLLMFLLATCLLAII------------------FVPQEMQTLRVVLATLGVGAASL 447
Query: 551 VGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLI 610
+ S E+ P++IR G+ A G A ++ + + L II+ ++
Sbjct: 448 GITCSTAQENELIPSIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFAIL 507
Query: 611 CIICILLLPESRDQNLPENISNGEH 635
+ +LLLPE+R+Q L ++I + E+
Sbjct: 508 SGLVVLLLPETRNQPLLDSIQDVEN 532
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 87.4 bits (215), Expect = 4e-17
Identities = 104/448 (23%), Positives = 183/448 (40%), Gaps = 40/448 (8%)
Query: 214 NVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLT 273
++ S+W L+ + ++KV A G+ G + G ++D GR+ V L ++F +
Sbjct: 96 SIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIA 155
Query: 274 VALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMP 333
S + F+ RF G G+ L + L E + + G
Sbjct: 156 NGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYA 215
Query: 334 GLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMN 393
L R W+ L L+ ++ L PES RWL + + A+ + ++NR
Sbjct: 216 LLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNR-- 273
Query: 394 PEGDIKGVIPELEKELSRRPKKV-CIVKVVGTRNLWKNIVVLC----VNSLTGYGIHHCF 448
+K L +R ++ + + R L + ++L V SL YG+
Sbjct: 274 ---KLKCTF-SLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGL--TL 327
Query: 449 ARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVV---RFLGRRGGLLLFMILTAL 505
+ +G + YA+ + I + S +C+ + ++ GR+ L F+ L L
Sbjct: 328 SAGDLGGSI--------YANLALSGLIEIPS-YPLCIYLINQKWFGRKRTLSAFLCLGGL 378
Query: 506 ASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPT 565
A L+ + L + D+G+ V S + S++G A ++ + +E+ PT
Sbjct: 379 ACLIVMFL-------PEKKDTGVFAVVN---SHSLSLLGKLTISAAFNIVYIYTSELYPT 428
Query: 566 VIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQN 625
VIR GLG + G + AP I + L I+F L + LLLPE+ +
Sbjct: 429 VIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSP 488
Query: 626 LPENISNGEHYTRQPLLPHKKGEQPLLL 653
L E S+ + Y+ + L GE+ L L
Sbjct: 489 LLETFSDLQVYSYRRL-----GEEALSL 511
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.141 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,394,028
Number of Sequences: 37866
Number of extensions: 1590263
Number of successful extensions: 9880
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 282
Number of HSP's that attempted gapping in prelim test: 8507
Number of HSP's gapped (non-prelim): 1643
length of query: 686
length of database: 18,247,518
effective HSP length: 109
effective length of query: 577
effective length of database: 14,120,124
effective search space: 8147311548
effective search space used: 8147311548
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.