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Search of human proteins with 16950636
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
(364 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens] 733 0.0
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens] 733 0.0
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens] 371 e-103
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens] 368 e-102
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens] 241 1e-63
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens] 224 9e-59
gi|134244587 endothelial differentiation, sphingolipid G-protein... 198 7e-51
gi|13540517 endothelial differentiation, sphingolipid G-protein-... 195 5e-50
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 169 4e-42
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens] 133 3e-31
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens] 133 3e-31
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens] 133 3e-31
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens] 133 3e-31
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens] 133 3e-31
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens] 133 3e-31
gi|119508433 melanocortin 4 receptor [Homo sapiens] 129 3e-30
gi|5174535 melanocortin 5 receptor [Homo sapiens] 129 5e-30
gi|170671732 melanocortin 3 receptor [Homo sapiens] 122 4e-28
gi|4885325 G protein-coupled receptor 3 [Homo sapiens] 122 4e-28
gi|4885295 G protein-coupled receptor 12 [Homo sapiens] 120 2e-27
gi|115305569 adenosine A1 receptor [Homo sapiens] 106 3e-23
gi|4501947 adenosine A1 receptor [Homo sapiens] 106 3e-23
gi|4885341 G protein-coupled receptor 6 [Homo sapiens] 106 3e-23
gi|4505127 melanocortin 2 receptor [Homo sapiens] 106 4e-23
gi|5921992 adenosine A2a receptor [Homo sapiens] 104 1e-22
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens] 103 2e-22
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 90 4e-18
gi|193083134 melanocortin 1 receptor [Homo sapiens] 89 5e-18
gi|4501951 adenosine A2b receptor [Homo sapiens] 89 6e-18
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 81 2e-15
>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 733 bits (1892), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 1 MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC 60
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
Sbjct: 1 MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC 60
Query: 61 IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST 120
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
Sbjct: 61 IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST 120
Query: 121 WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA 180
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
Sbjct: 121 WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA 180
Query: 181 IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS 240
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
Sbjct: 181 IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS 240
Query: 241 RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA 300
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
Sbjct: 241 RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA 300
Query: 301 EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND 360
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
Sbjct: 301 EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND 360
Query: 361 HSVV 364
HSVV
Sbjct: 361 HSVV 364
>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 733 bits (1892), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 1 MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC 60
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
Sbjct: 1 MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC 60
Query: 61 IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST 120
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
Sbjct: 61 IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST 120
Query: 121 WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA 180
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
Sbjct: 121 WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA 180
Query: 181 IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS 240
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
Sbjct: 181 IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS 240
Query: 241 RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA 300
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
Sbjct: 241 RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA 300
Query: 301 EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND 360
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
Sbjct: 301 EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND 360
Query: 361 HSVV 364
HSVV
Sbjct: 361 HSVV 364
>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
Length = 351
Score = 371 bits (953), Expect = e-103
Identities = 176/307 (57%), Positives = 232/307 (75%), Gaps = 1/307 (0%)
Query: 23 QCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHF 82
QC+YNE+I FFYN SGK L++ W +V+ LG+TV + ++L NLLV+ AI NRRFH
Sbjct: 6 QCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQ 65
Query: 83 PIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAI 142
PIYYL+ NLAAAD FAG+AY +LMF+TGP T RL++ W LRQGL+DTSLTASVA LLAI
Sbjct: 66 PIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAI 125
Query: 143 AIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLY 202
A+ERH +V +QLH+R+ RVV++IV +W A+ +G +P+ W+C+C ++ CS MAPL
Sbjct: 126 AVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLL 185
Query: 203 SDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVI 262
S SYL WA+ +L+ F++MV +Y IF YVR+R RM+ H S R R+T +SL+KTVVI
Sbjct: 186 SRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVI 245
Query: 263 VLGAFIICWTPGLVLLLLD-VCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSAT 321
+LGAF++CWTPG V+LLLD + C C+VLA EK+FLLLAE NS +N +YS RD EM T
Sbjct: 246 ILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRT 305
Query: 322 FRQILCC 328
FR++LCC
Sbjct: 306 FRRLLCC 312
>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
Length = 353
Score = 368 bits (944), Expect = e-102
Identities = 173/338 (51%), Positives = 250/338 (73%), Gaps = 11/338 (3%)
Query: 19 MNEPQCFYNESIAFFYNRSGKHLATEWN-TVSKLVMGLGITVCIFIMLANLLVMVAIYVN 77
MNE C Y++ + FFYNRS +W T +V+ +G C+FI +N LV+ A+ N
Sbjct: 1 MNE--CHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKN 58
Query: 78 RRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVA 137
R+FHFP YYL+ANLAAADFFAG+AY +LMFNTGP ++ LTV+ W LRQGL+D+SLTAS+
Sbjct: 59 RKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLT 118
Query: 138 NLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSN 197
NLL IA+ERH+++ RM++H+ ++ +RV ++I+++W +AI MGA+P++GWNC+C+I CS+
Sbjct: 119 NLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSS 178
Query: 198 MAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLL 257
+AP+YS SYLVFW + NL+ F++MVV+Y I+ YV+++T +S H+SG R T M L+
Sbjct: 179 LAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLM 238
Query: 258 KTVVIVLGAFIICWTPGLVLLLLD-VCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDK 316
KTV+ VLGAF++CWTPGLV+LLLD + C QC V +++FLLLA NS +NPIIYSY+D+
Sbjct: 239 KTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDE 298
Query: 317 EMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILA 354
+M T ++++CC ENP +R S + T+L+
Sbjct: 299 DMYGTMKKMICCFSQENP-------ERRPSRIPSTVLS 329
>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
Length = 382
Score = 241 bits (614), Expect = 1e-63
Identities = 132/357 (36%), Positives = 215/357 (60%), Gaps = 18/357 (5%)
Query: 6 TSIPVISQPQFTAMNEPQCFYN-ESIAFFYNRSGK-HLATEWNTVSKLVMGLGITVCIFI 63
TS+P++ + + + + N + I YN +GK +++ + KL + I +C FI
Sbjct: 4 TSVPLVKAHRSSVSD----YVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFI 59
Query: 64 MLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLL 123
+L N+ V++ I+ ++FH P+YY + NLA +D AG+AY + +G T +LT + W L
Sbjct: 60 ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL 119
Query: 124 RQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPS 183
R+G + +L+ASV +LLAIAIER+IT+ +M+LH +N R+ ++I W +++++G +P
Sbjct: 120 REGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPI 179
Query: 184 VGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS--R 241
+GWNCI + +CS + PLY Y++F + + +V+LY I+ VR R+ R++ +
Sbjct: 180 MGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRK 239
Query: 242 HSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCC--PQCDVLAYEKFFLLL 299
+ S R+ + ++LLKTV+IVL FI CW P +LLLLDV C CD+L ++FL+L
Sbjct: 240 NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVL 299
Query: 300 AEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGV 356
A NS NPIIY+ +KEM F +I+ C + P+G SA I+AG+
Sbjct: 300 AVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKC--PSGD------SAGKFKRPIIAGM 348
>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
Length = 378
Score = 224 bits (571), Expect = 9e-59
Identities = 116/305 (38%), Positives = 183/305 (60%), Gaps = 9/305 (2%)
Query: 27 NESIAFFYNRSGKHLAT--EWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPI 84
NE++ Y GK E + S L L + +C FI+L NL+V++AI+ N +FH +
Sbjct: 15 NETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRM 74
Query: 85 YYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAI 144
Y+ + NLA D AG+AY + +G T L+ + W LR+G + +L AS +LLAIAI
Sbjct: 75 YFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAI 134
Query: 145 ERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSD 204
ERH+T+ +M+ + RV ++I + W +A +GA+P +GWNC+ ++ +CS + PLYS
Sbjct: 135 ERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSK 194
Query: 205 SYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVL 264
Y+ F V +V+LYA I+ V+ + +++ H+ N + M+LL+TVVIV+
Sbjct: 195 KYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHN-----NSERSMALLRTVVIVV 249
Query: 265 GAFIICWTPGLVLLLLDVCC--PQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATF 322
FI CW+P +L L+DV C C +L ++F++LA NSAMNP+IY+ KEM F
Sbjct: 250 SVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAF 309
Query: 323 RQILC 327
+++C
Sbjct: 310 FRLVC 314
>gi|134244587 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 5 [Homo sapiens]
Length = 353
Score = 198 bits (503), Expect = 7e-51
Identities = 107/321 (33%), Positives = 179/321 (55%), Gaps = 14/321 (4%)
Query: 34 YNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAA 93
YN + + L T+ T ++ + +C I++ NLLV++A+ N +FH +Y + NLAA
Sbjct: 18 YNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAA 77
Query: 94 ADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRM 153
+D AG+A+ +G T RLT W R+G +L+ASV +LLAIAIERH+ + ++
Sbjct: 78 SDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKV 137
Query: 154 QLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIF 213
+L+ + R++++I W +++V+G +P +GWNC+ +E CS + PLY+ Y++
Sbjct: 138 KLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTI 197
Query: 214 NLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTP 273
+ + +V LY I+ VR M+ + ++LLKTV IVLG FI+CW P
Sbjct: 198 FSIILLAIVALYVRIYCVVRSSHADMAAPQT---------LALLKTVTIVLGVFIVCWLP 248
Query: 274 GLVLLLLDVCCP--QCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRS 331
+LLLD CP C +L +F ++ NS +NP+IY++R +++ + L C R
Sbjct: 249 AFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWR- 307
Query: 332 ENPTGPTEGSDRSASSLNHTI 352
P +G R + +H +
Sbjct: 308 --PGVGVQGRRRGGTPGHHLL 326
>gi|13540517 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 8 [Homo sapiens]
Length = 398
Score = 195 bits (496), Expect = 5e-50
Identities = 113/331 (34%), Positives = 185/331 (55%), Gaps = 11/331 (3%)
Query: 27 NESIAFFYNRSGKHLATEWNTVSKLVMG--LGITVCIFIMLANLLVMVAIYVNRRFHFPI 84
+E I YN +GK + + L + + VC FI+L NL V++ + + RFH P+
Sbjct: 12 SEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPM 71
Query: 85 YYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAI 144
+ L+ +L +D AG AY + +GP T +L+ + W R+G + +LTASV +LLAIA+
Sbjct: 72 FLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIAL 131
Query: 145 ERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSD 204
ER +T+ R S R + + W +++++G +P++GWNC+ ++ CS + PLY+
Sbjct: 132 ERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAK 191
Query: 205 SYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRH------SSGPRRNRDTMMSLLK 258
+Y++F + + + LYA I+ VR R+ +S R + ++LL+
Sbjct: 192 AYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLR 251
Query: 259 TVVIVLGAFIICWTPGLVLLLLDVCCPQ--CDVLAYEKFFLLLAEFNSAMNPIIYSYRDK 316
T+ +VL AF+ CW P +LLLLDV CP C VL FL LA NS +NPIIY+ ++
Sbjct: 252 TLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNR 311
Query: 317 EMSATFRQILCCQRSENPTGPTEGSDRSASS 347
++ +++CC R P+ GS +SAS+
Sbjct: 312 DLRHALLRLVCCGRHSCGRDPS-GSQQSASA 341
>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
Length = 384
Score = 169 bits (428), Expect = 4e-42
Identities = 104/309 (33%), Positives = 157/309 (50%), Gaps = 11/309 (3%)
Query: 26 YNESIAFFYNRSGKHLATEWNTVSKL--VMGLGITVCIFIMLANLLVMVAIYVNRRFHFP 83
++ I YN SG+ L + GL + ++L NLLV+ AI + R
Sbjct: 21 HSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRW 80
Query: 84 IYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIA 143
+YY + N+ +D G AY + +G T RL + W LR+GL+ T+L AS +LL A
Sbjct: 81 VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTA 140
Query: 144 IERHITVFRMQLHT-RMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLY 202
ER T+ R + RV I + W +A ++G +P +GWNC+C + CS++ PLY
Sbjct: 141 GERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLY 200
Query: 203 SDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVI 262
S Y++F + ++ LY IF V+ + R ++ + R LLKTV++
Sbjct: 201 SKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARR-----LLKTVLM 255
Query: 263 VLGAFIICWTPGLVLLLLDVCCPQCDVLAYEK---FFLLLAEFNSAMNPIIYSYRDKEMS 319
+L AF++CW P LLL DV Y + + L LA NSA+NPIIYS+R +E+
Sbjct: 256 ILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVC 315
Query: 320 ATFRQILCC 328
LCC
Sbjct: 316 RAVLSFLCC 324
>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 133 bits (334), Expect = 3e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 59 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 118
Query: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 119 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 179 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 238
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 418
Query: 332 ENPTGPTEG 340
P + G
Sbjct: 419 AQPLDNSMG 427
>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 133 bits (334), Expect = 3e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 59 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 118
Query: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 119 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 179 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 238
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 418
Query: 332 ENPTGPTEG 340
P + G
Sbjct: 419 AQPLDNSMG 427
>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 133 bits (334), Expect = 3e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 59 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 118
Query: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 119 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 179 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 238
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 418
Query: 332 ENPTGPTEG 340
P + G
Sbjct: 419 AQPLDNSMG 427
>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 133 bits (334), Expect = 3e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 59 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 118
Query: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 119 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 179 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 238
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 418
Query: 332 ENPTGPTEG 340
P + G
Sbjct: 419 AQPLDNSMG 427
>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 133 bits (334), Expect = 3e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 59 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 118
Query: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 119 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 179 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 238
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 418
Query: 332 ENPTGPTEG 340
P + G
Sbjct: 419 AQPLDNSMG 427
>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
Length = 439
Score = 133 bits (334), Expect = 3e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 26 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 85
Query: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 86 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 145
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 146 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 205
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 206 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 265
Query: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325
Query: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 326 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 385
Query: 332 ENPTGPTEG 340
P + G
Sbjct: 386 AQPLDNSMG 394
>gi|119508433 melanocortin 4 receptor [Homo sapiens]
Length = 332
Score = 129 bits (325), Expect = 3e-30
Identities = 82/286 (28%), Positives = 147/286 (51%), Gaps = 32/286 (11%)
Query: 57 ITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLA------YFYLMFNTG 110
+T+ + +L N+LV+VAI N+ H P+Y+ + +LA AD ++ L+ +T
Sbjct: 52 VTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTD 111
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVF-RMQLHTRMSNRRVVVVIV 169
+ + TV+ + +I +SL AS+ +LL+IA++R+ T+F +Q H M+ +RV ++I
Sbjct: 112 TDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIIS 171
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNL--VTFVVMVVLYAH 227
IW V G + +YSDS V + + +M LY H
Sbjct: 172 CIWAACTVSGI-----------------LFIIYSDSSAVIICLITMFFTMLALMASLYVH 214
Query: 228 IFGYVRQRTMRMS-RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQ 286
+F R R++ +G R M + T+ I++G F++CW P + L+ + CPQ
Sbjct: 215 MFLMARLHIKRIAVLPGTGAIRQGANMKGAI-TLTILIGVFVVCWAPFFLHLIFYISCPQ 273
Query: 287 ----CDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCC 328
+++ +L+L NS ++P+IY+ R +E+ TF++I+CC
Sbjct: 274 NPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICC 319
>gi|5174535 melanocortin 5 receptor [Homo sapiens]
Length = 325
Score = 129 bits (323), Expect = 5e-30
Identities = 84/292 (28%), Positives = 145/292 (49%), Gaps = 41/292 (14%)
Query: 57 ITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAY------FYLMFNTG 110
+T+ + +L N+LV+ AI N+ H P+Y+ + +LA AD ++ YL+
Sbjct: 44 LTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLL---- 99
Query: 111 PNTRRLTVSTWLLRQ------GLIDTSLTASVANLLAIAIERHITVF-RMQLHTRMSNRR 163
N + L ++ +R +I S+ AS+ +LLAIA++R++T+F ++ H M+ RR
Sbjct: 100 -NNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARR 158
Query: 164 VVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNL--VTFVVM 221
+I IW C + LYS+S V + ++ ++
Sbjct: 159 SGAIIAGIWAFCT-----------------GCGIVFILYSESTYVILCLISMFFAMLFLL 201
Query: 222 VVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLD 281
V LY H+F R R++ + T M TV ++LG F +CW P + L L
Sbjct: 202 VSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLM 261
Query: 282 VCCPQ---CD-VLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQ 329
+ CPQ C +++ +L+L NS M+P+IY++R +EM TF++I+CC+
Sbjct: 262 LSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCR 313
>gi|170671732 melanocortin 3 receptor [Homo sapiens]
Length = 323
Score = 122 bits (307), Expect = 4e-28
Identities = 88/312 (28%), Positives = 152/312 (48%), Gaps = 37/312 (11%)
Query: 32 FFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANL 91
FF N+S + ++ + LGI +L N+LV++A+ N H P+Y+ + +L
Sbjct: 25 FFSNQSSSAFCEQVFIKPEVFLSLGIVS----LLENILVILAVVRNGNLHSPMYFFLCSL 80
Query: 92 AAADFFAGLAY-FYLMFNTGPNTRRLTVSTWLLRQ------GLIDTSLTASVANLLAIAI 144
A AD ++ + ++ LT ++ +I SL AS+ NLLAIA+
Sbjct: 81 AVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAV 140
Query: 145 ERHITVF-RMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYS 203
+R++T+F ++ H+ M+ R+ + +IV IW V G + V YS
Sbjct: 141 DRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIV-----------------YS 183
Query: 204 DSYLVFWAIFNL--VTFVVMVVLYAHIFGYVRQRTMRMSR--HSSGPRRNRDTMMSLLKT 259
+S +V + + ++M LY H+F + R R++ + G + + M T
Sbjct: 184 ESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVT 243
Query: 260 VVIVLGAFIICWTPGLVLLLLDVCCPQCDVL----AYEKFFLLLAEFNSAMNPIIYSYRD 315
+ I+LG FI CW P + L+L + CP A+ +L+L NS ++P+IY++R
Sbjct: 244 ITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRS 303
Query: 316 KEMSATFRQILC 327
E+ TFR+ILC
Sbjct: 304 LELRNTFREILC 315
>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
Length = 330
Score = 122 bits (307), Expect = 4e-28
Identities = 84/282 (29%), Positives = 144/282 (51%), Gaps = 22/282 (7%)
Query: 57 ITVCI---FIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLA---YFYLMFNTG 110
+ +CI + N LV+ I F P++ L+ +LA AD AGL +F +F G
Sbjct: 45 VVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIG 104
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMSNRRVVVVIV 169
+ L+ G++ + TAS+ +LLAI ++R+++++ + ++ + R V++
Sbjct: 105 ------SAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLA 158
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
++W A+ +G +P + WNC+ + C + PL S ++LV AI + F +M+ LYA I
Sbjct: 159 LVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQIC 217
Query: 230 GYV--RQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLL-DVCCPQ 286
V + + + RH P + + T+ +VLGAF CW P V LL D P
Sbjct: 218 RIVCRHAQQIALQRHLL-PASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPP 276
Query: 287 CDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCC 328
Y LL A +NS +NPIIY++R++++ + CC
Sbjct: 277 ----LYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
Length = 334
Score = 120 bits (300), Expect = 2e-27
Identities = 84/283 (29%), Positives = 145/283 (51%), Gaps = 18/283 (6%)
Query: 63 IMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWL 122
I N +V++ I+ N P++ L+ +LA AD AG+ L+ N + +T L
Sbjct: 58 ISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIG---LITNFVFAYLLQSEATKL 114
Query: 123 LRQGLIDTSLTASVANLLAIAIERHITVF-RMQLHTRMSNRRVVVVIVVIWTMAIVMGAI 181
+ GLI S +ASV +LLAI ++R+++++ + H+ + V++V++W +I +G +
Sbjct: 115 VTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLL 174
Query: 182 PSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS- 240
P +GWNC+ D CS + PL ++ + F L F +M+ LY I V + +++
Sbjct: 175 PVMGWNCLRDESTCSVVRPLTKNNAAILSVSF-LFMFALMLQLYIQICKIVMRHAHQIAL 233
Query: 241 RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTP-GLVLLLLDVCCPQCDVLAYEKFFLLL 299
+H + T + T+ I+LG F CW P L L+ D P Y LL
Sbjct: 234 QHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPS----IYTYATLLP 289
Query: 300 AEFNSAMNPIIYSYRDKEMSATFRQILC-------CQRSENPT 335
A +NS +NP+IY++R++E+ I C QR+ +P+
Sbjct: 290 ATYNSIINPVIYAFRNQEIQKALCLICCGCIPSSLAQRARSPS 332
>gi|115305569 adenosine A1 receptor [Homo sapiens]
Length = 326
Score = 106 bits (265), Expect = 3e-23
Identities = 80/296 (27%), Positives = 142/296 (47%), Gaps = 29/296 (9%)
Query: 53 MGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYL--MFNTG 110
+G+ + + + + N+LV+ A+ VN+ + + +LA AD G L + N G
Sbjct: 13 IGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIG 72
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRM--SNRRVVVVI 168
P T T L+ + +S+ LLAIA++R++ V ++ L +M + RR V I
Sbjct: 73 PQTY---FHTCLMVACPVLILTQSSILALLAIAVDRYLRV-KIPLRYKMVVTPRRAAVAI 128
Query: 169 VVIWTMAIVMGAIPSVGWNCICDIENC-------------SNMAPLYSDSYLVFWAIFNL 215
W ++ V+G P GWN + +E + S Y+V++ F
Sbjct: 129 AGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVW 188
Query: 216 VT--FVVMVVLYAHIFGYVR-QRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWT 272
V ++MV++Y +F +R Q ++S S P++ + + K++ ++L F + W
Sbjct: 189 VLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWL 248
Query: 273 PGLVLLLLDVCCPQC---DVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQI 325
P +L + + CP C +L Y F L NSAMNPI+Y++R ++ TF +I
Sbjct: 249 PLHILNCITLFCPSCHKPSILTYIAIF--LTHGNSAMNPIVYAFRIQKFRVTFLKI 302
>gi|4501947 adenosine A1 receptor [Homo sapiens]
Length = 326
Score = 106 bits (265), Expect = 3e-23
Identities = 80/296 (27%), Positives = 142/296 (47%), Gaps = 29/296 (9%)
Query: 53 MGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYL--MFNTG 110
+G+ + + + + N+LV+ A+ VN+ + + +LA AD G L + N G
Sbjct: 13 IGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIG 72
Query: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRM--SNRRVVVVI 168
P T T L+ + +S+ LLAIA++R++ V ++ L +M + RR V I
Sbjct: 73 PQTY---FHTCLMVACPVLILTQSSILALLAIAVDRYLRV-KIPLRYKMVVTPRRAAVAI 128
Query: 169 VVIWTMAIVMGAIPSVGWNCICDIENC-------------SNMAPLYSDSYLVFWAIFNL 215
W ++ V+G P GWN + +E + S Y+V++ F
Sbjct: 129 AGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVW 188
Query: 216 VT--FVVMVVLYAHIFGYVR-QRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWT 272
V ++MV++Y +F +R Q ++S S P++ + + K++ ++L F + W
Sbjct: 189 VLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWL 248
Query: 273 PGLVLLLLDVCCPQC---DVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQI 325
P +L + + CP C +L Y F L NSAMNPI+Y++R ++ TF +I
Sbjct: 249 PLHILNCITLFCPSCHKPSILTYIAIF--LTHGNSAMNPIVYAFRIQKFRVTFLKI 302
>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
Length = 362
Score = 106 bits (265), Expect = 3e-23
Identities = 78/275 (28%), Positives = 135/275 (49%), Gaps = 18/275 (6%)
Query: 67 NLLVMVAIYVNRRFHFPIYYLMANLAAADFFAG---LAYFYLMFNTGPNTRRLTVSTWLL 123
N LV+ I P++ L+ +LA AD AG + +F + T LL
Sbjct: 90 NALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSET------VSLL 143
Query: 124 RQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMSNRRVVVVIVVIWTMAIVMGAIP 182
G + S ASV++LLAI ++R+++++ + ++R + V +++ WT+++ +G +P
Sbjct: 144 TVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLP 203
Query: 183 SVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYV--RQRTMRMS 240
+GWNC+ + CS + PL + A F +V F +M+ LY I V + +
Sbjct: 204 VLGWNCLAERAACSVVRPLARSHVALLSAAFFMV-FGIMLHLYVRICQVVWRHAHQIALQ 262
Query: 241 RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA 300
+H P T + T+ +VLG F W P + ++ D Y LL A
Sbjct: 263 QHCLAPPHLAATRKG-VGTLAVVLGTFGASWLPFAIYCVVG---SHEDPAVYTYATLLPA 318
Query: 301 EFNSAMNPIIYSYRDKEMSATFRQILC-CQRSENP 334
+NS +NPIIY++R++E+ +LC C +S+ P
Sbjct: 319 TYNSMINPIIYAFRNQEIQRALWLLLCGCFQSKVP 353
>gi|4505127 melanocortin 2 receptor [Homo sapiens]
Length = 297
Score = 106 bits (264), Expect = 4e-23
Identities = 83/285 (29%), Positives = 140/285 (49%), Gaps = 34/285 (11%)
Query: 58 TVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGL-----AYFYLMFNTGPN 112
T+ I +L NL+V++A++ N+ P+Y+ + +LA +D L ++ N G
Sbjct: 33 TISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYL 92
Query: 113 TRRLTVSTWL--LRQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMSNRRVVVVIV 169
R + T + L SL S+ +L IA +R+IT+F ++ H+ ++ RR VVV+
Sbjct: 93 KPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLT 152
Query: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
VIWT G + S+ P + + F ++F L+ V ++ LY H+F
Sbjct: 153 VIWTFCTGTGITMVI----------FSHHVP----TVITFTSLFPLM-LVFILCLYVHMF 197
Query: 230 GYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDV 289
R T ++ S+ PR N M T+ I+LG FI CW P ++ +LL CP
Sbjct: 198 LLARSHTRKI---STLPRAN----MKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPY 250
Query: 290 LA-YEKFFL---LLAEFNSAMNPIIYSYRDKEMSATFRQILCCQR 330
A Y F +L N+ ++P IY++R E+ F++++ C R
Sbjct: 251 CACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSR 295
>gi|5921992 adenosine A2a receptor [Homo sapiens]
Length = 412
Score = 104 bits (259), Expect = 1e-22
Identities = 79/304 (25%), Positives = 147/304 (48%), Gaps = 32/304 (10%)
Query: 49 SKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAY--FYLM 106
S + + + + + + +L N+LV A+++N Y + +LAAAD G+ F +
Sbjct: 6 SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAIT 65
Query: 107 FNTGPNTRR---LTVSTWLLRQGLIDTSLTASVANLLAIAIERHITV-FRMQLHTRMSNR 162
+TG L ++ ++L +S+ +LLAIAI+R+I + ++ + ++
Sbjct: 66 ISTGFCAACHGCLFIACFVL------VLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT 119
Query: 163 RVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSN---------MAPLYSD----SYLVF 209
R +I + W ++ +G P +GWN + N +A L+ D +Y+V+
Sbjct: 120 RAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVY 179
Query: 210 WAIFN--LVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLL---KTVVIVL 264
+ F LV ++M+ +Y IF R++ +M R R T+ + K++ I++
Sbjct: 180 FNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIV 239
Query: 265 GAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFL--LLAEFNSAMNPIIYSYRDKEMSATF 322
G F +CW P ++ CP C +L +L+ NS +NP IY+YR +E TF
Sbjct: 240 GLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTF 299
Query: 323 RQIL 326
R+I+
Sbjct: 300 RKII 303
>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
Length = 360
Score = 103 bits (258), Expect = 2e-22
Identities = 74/269 (27%), Positives = 127/269 (47%), Gaps = 10/269 (3%)
Query: 65 LANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLL 123
L N+ V+ I + + P Y + +LA ADF A + + N + + +LL
Sbjct: 49 LENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLL 108
Query: 124 RQGLIDTSLTASVANLLAIAIERHITV-FRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIP 182
+ G + + TASV +LL AI+R++ + + ++ R +V + ++W ++ ++ +P
Sbjct: 109 KIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLP 168
Query: 183 SVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRH 242
+GW C C CS + PL + YL+ W +F F ++ Y H+ Q +S H
Sbjct: 169 LMGWTC-CP-RPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGH 226
Query: 243 SS----GPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCD-VLAYEKFFL 297
G R R + L KT+ +VL +ICW P L L+ + D V F
Sbjct: 227 QDRQVPGMARMR-LDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCS 285
Query: 298 LLAEFNSAMNPIIYSYRDKEMSATFRQIL 326
+L NS +NP+IY+ R E+ ++ L
Sbjct: 286 MLCLINSMVNPVIYALRSGEIRSSAHHCL 314
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 89.7 bits (221), Expect = 4e-18
Identities = 87/335 (25%), Positives = 142/335 (42%), Gaps = 74/335 (22%)
Query: 51 LVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTG 110
LV+G I +F ++ N+LV++++ NR P Y + NLA AD L F
Sbjct: 50 LVLGAFI---LFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLL-------LSFTVL 99
Query: 111 PNTRRLTV-STWLLRQGLID-------TSLTASVANLLAIAIERHITV-FRMQLHTRMSN 161
P + L V W+L + D TAS+ +L AI+I+R+I V + +Q T ++
Sbjct: 100 PFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTR 159
Query: 162 RRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFN-----LV 216
R+ ++ ++ +W ++ V+ P +GW E N + F+A+F+ +
Sbjct: 160 RKAILALLSVWVLSTVISIGPLLGWK-----EPAPNDDKECGVTEEPFYALFSSLGSFYI 214
Query: 217 TFVVMVVLYAHIFGYVRQRTMRMS----RHSSGPRR----------NRDTMMS------- 255
V++V+Y ++ ++ T + + S + + DT+ S
Sbjct: 215 PLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHN 274
Query: 256 -----------------LLKTVVIVLGAFIICWTPGLVLL----LLDVCCPQCDVLAYEK 294
KT+ IV+G FI+CW P + L L P V K
Sbjct: 275 PRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVF---K 331
Query: 295 FFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQ 329
L FNS +NPIIY KE F +IL CQ
Sbjct: 332 VVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQ 366
>gi|193083134 melanocortin 1 receptor [Homo sapiens]
Length = 317
Score = 89.4 bits (220), Expect = 5e-18
Identities = 73/291 (25%), Positives = 136/291 (46%), Gaps = 34/291 (11%)
Query: 54 GLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFY-----LMFN 108
GL +++ + ++ N LV+ I NR H P+Y + LA +D + L+
Sbjct: 43 GLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLE 102
Query: 109 TGPNTRRLTVSTWLLRQGLID----TSLTASVANLLAIAIERHITVF-RMQLHTRMSNRR 163
G R V L +ID +S+ +S+ L AIA++R+I++F ++ H+ ++ R
Sbjct: 103 AGALVARAAVLQQL--DNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPR 160
Query: 164 VVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVV 223
+ IW ++V + ++ + + L+ +F L V+M V
Sbjct: 161 ARRAVAAIWVASVVFSTLFIAYYDHV---------------AVLLCLVVFFLAMLVLMAV 205
Query: 224 LYAHIFGYVRQRTMRMSR-HSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDV 282
LY H+ Q ++R H ++ + T+ I+LG F +CW P + L L V
Sbjct: 206 LYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIV 265
Query: 283 CCPQ---CDVLAYEKF--FLLLAEFNSAMNPIIYSYRDKEMSATFRQILCC 328
CP+ C + ++ F FL L N+ ++P+IY++ +E+ T +++L C
Sbjct: 266 LCPEHPTCGCI-FKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTC 315
>gi|4501951 adenosine A2b receptor [Homo sapiens]
Length = 332
Score = 89.0 bits (219), Expect = 6e-18
Identities = 76/307 (24%), Positives = 138/307 (44%), Gaps = 33/307 (10%)
Query: 47 TVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLM 106
T L + L + + + N+LV A+ P Y + +LAAAD GL F +
Sbjct: 5 TQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGL--FAIP 62
Query: 107 FNTGPNTRRLTVSTWLLRQGLIDTSLT-ASVANLLAIAIERHITV-FRMQLHTRMSNRRV 164
F + T L LT +S+ +LLA+A++R++ + ++ + ++ R
Sbjct: 63 FAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRA 122
Query: 165 VVVIVVIWTMAIVMGAIPSVGWNC------------------ICDIENC--SNMAPLYSD 204
VI V+W +A +G P +GWN C + C N+ P+
Sbjct: 123 RGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPM--- 179
Query: 205 SYLVFWAIFNLVT--FVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVI 262
SY+V++ F V ++M+V+Y IF V R ++ + R + K++ +
Sbjct: 180 SYMVYFNFFGCVLPPLLIMLVIYIKIF-LVACRQLQRTELMDHSRTTLQREIHAAKSLAM 238
Query: 263 VLGAFIICWTPGLVLLLLDVCCPQCDVLAYE---KFFLLLAEFNSAMNPIIYSYRDKEMS 319
++G F +CW P + + + P + +LL+ NS +NPI+Y+YR+++
Sbjct: 239 IVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFR 298
Query: 320 ATFRQIL 326
TF +I+
Sbjct: 299 YTFHKII 305
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 80.9 bits (198), Expect = 2e-15
Identities = 77/323 (23%), Positives = 146/323 (45%), Gaps = 53/323 (16%)
Query: 52 VMGLGITVCIFIM---LANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFN 108
V+G+GI + + ++ N+LV+ AI R Y + +LA AD GLA + F
Sbjct: 33 VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV--VPFG 90
Query: 109 TGPNTRRLTV--STWLLRQGLIDT-SLTASVANLLAIAIERHITVFR-MQLHTRMSNRRV 164
++ + W ID +TAS+ L IA++R+ + + + ++ +
Sbjct: 91 AAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKA 150
Query: 165 VVVIVVIWTMAIVMGAIP-SVGW---------NCICDIENC---SNMAPLYSDSYLVFWA 211
V+I+++W ++ + +P + W NC + C +N A + S + F+
Sbjct: 151 RVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFY- 209
Query: 212 IFNLVTFVVMVVLYAHIFGYVRQRTMRMS------------------RHSSGPRRNRDTM 253
V V+MV +Y+ +F +++ ++ R G RR+
Sbjct: 210 ----VPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFC 265
Query: 254 MS---LLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLL--LAEFNSAMNP 308
+ LKT+ I++G F +CW P ++ ++ V Q +++ E + LL + NS NP
Sbjct: 266 LKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI--QDNLIRKEVYILLNWIGYVNSGFNP 323
Query: 309 IIYSYRDKEMSATFRQILCCQRS 331
+IY R + F+++LC +RS
Sbjct: 324 LIYC-RSPDFRIAFQELLCLRRS 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,898,420
Number of Sequences: 37866
Number of extensions: 443560
Number of successful extensions: 2799
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 360
Number of HSP's successfully gapped in prelim test: 282
Number of HSP's that attempted gapping in prelim test: 1683
Number of HSP's gapped (non-prelim): 846
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.